Sample records for operating procedures eops

  1. Mental workload measurement for emergency operating procedures in digital nuclear power plants.

    PubMed

    Gao, Qin; Wang, Yang; Song, Fei; Li, Zhizhong; Dong, Xiaolu

    2013-01-01

    Mental workload is a major consideration for the design of emergency operation procedures (EOPs) in nuclear power plants. Continuous and objective measures are desired. This paper compares seven mental workload measurement methods (pupil size, blink rate, blink duration, heart rate variability, parasympathetic/sympathetic ratio, total power and (Goals, Operations, Methods, and Section Rules)-(Keystroke Level Model) GOMS-KLM-based workload index) with regard to sensitivity, validity and intrusiveness. Eighteen participants performed two computerised EOPs of different complexity levels, and mental workload measures were collected during the experiment. The results show that the blink rate is sensitive to both the difference in the overall task complexity and changes in peak complexity within EOPs, that the error rate is sensitive to the level of arousal and correlate to the step error rate and that blink duration increases over the task period in both low and high complexity EOPs. Cardiac measures were able to distinguish tasks with different overall complexity. The intrusiveness of the physiological instruments is acceptable. Finally, the six physiological measures were integrated using group method of data handling to predict perceived overall mental workload. The study compared seven measures for evaluating the mental workload with emergency operation procedure in nuclear power plants. An experiment with simulated procedures was carried out, and the results show that eye response measures are useful for assessing temporal changes of workload whereas cardiac measures are useful for evaluating the overall workload.

  2. Development of Procedures to Implement EOPS Cost Effectiveness Standards Model and Continued Evaluation of These Procedures by Selected Community Colleges during the 1974-75 Academic Year. EOPS Special Project 74-101.

    ERIC Educational Resources Information Center

    Aughinbaugh, Lorine A.; And Others

    Four products were developed during the second year of the Extended Opportunity Programs and Services (EOPS) cost effectiveness study for California community colleges. This project report presents: (1) a revised cost analysis form for state-level reporting of institutional program effectiveness data and per-student costs by EOPS program category…

  3. 75 FR 63209 - Indiana Michigan Power Company; Notice of Consideration of Issuance of Amendment to Facility...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... emergency operating procedures (EOP), and site survey monitoring that support modification of emergency plan... Power Company; Notice of Consideration of Issuance of Amendment to Facility Operating License, Proposed... Regulatory Commission (the Commission) is considering issuance of an amendment to Facility Operating License...

  4. Electro-Osmotic Pulse Technology: A Novel Solution to Severe Water Intrusion Problems in Earth Covered Magazines

    DTIC Science & Technology

    2006-11-01

    The situation was deemed ideal for ElectroOsmotic Pulse (EOP) technology. A Return-on-Investment (ROI) study concluded that EOP is also the most...various steps in the EOP system installation: Figure 15 shows the chipping operation for installing a ¾-inch wide mixed metal-oxide coated titanium

  5. Operative EOP activities in VNIIFTRI

    NASA Astrophysics Data System (ADS)

    Pasynok, S.; Bezmenov, I.; Kaufman, M.

    2015-08-01

    VNIIFTRI as the Russian Main Metrological Center of Time, Frequencies and Earth Rotation Service carried out the EOP activities for many years. The brief information about these activities is presented.

  6. Russian State Time and Earth Rotation Service: Observations, Eop Series, Prediction

    NASA Astrophysics Data System (ADS)

    Kaufman, M.; Pasynok, S.

    2010-01-01

    Russian State Time, Frequency and Earth Rotation Service provides the official EOP data and time for use in scientific, technical and metrological works in Russia. The observations of GLONASS and GPS on 30 stations in Russia, and also the Russian and worldwide observations data of VLBI (35 stations) and SLR (20 stations) are used now. To these three series of EOP the data calculated in two other Russian analysis centers are added: IAA (VLBI, GPS and SLR series) and MCC (SLR). Joint processing of these 7 series is carried out every day (the operational EOP data for the last day and the predicted values for 50 days). The EOP values are weekly refined and systematic errors of every individual series are corrected. The combined results become accessible on the VNIIFTRI server (ftp.imvp.ru) approximately at 6h UT daily.

  7. Adding source positions to the IVS Combination

    NASA Astrophysics Data System (ADS)

    Bachmann, S.; Thaller, D.

    2016-12-01

    Simultaneous estimation of source positions, Earth orientation parameters (EOPs) and station positions in one common adjustment is crucial for a consistent generation of celestial and terrestrial reference frame (CRF and TRF, respectively). VLBI is the only technique to guarantee this consistency. Previous publications showed that the VLBI intra-technique combination could improve the quality of the EOPs and station coordinates compared to the individual contributions. By now, the combination of EOP and station coordinates is well established within the IVS and in combination with other space geodetic techniques (e.g. inter-technique combined TRF like the ITRF). Most of the contributing IVS Analysis Centers (AC) now provide source positions as a third parameter type (besides EOP and station coordinates), which have not been used for an operational combined solution yet. A strategy for the combination of source positions has been developed and integrated into the routine IVS combination. Investigations are carried out to compare the source positions derived from different IVS ACs with the combined estimates to verify whether the source positions are improved by the combination, as it has been proven for EOP and station coordinates. Furthermore, global solutions of source positions, i.e., so-called catalogues describing a CRF, are generated consistently with the TRF similar to the IVS operational combined quarterly solution. The combined solutions of the source positions time series and the consistently generated TRF and CRF are compared internally to the individual solutions of the ACs as well as to external CRF catalogues and TRFs. Additionally, comparisons of EOPs based on different CRF solutions are presented as an outlook for consistent EOP, CRF and TRF realizations.

  8. 76 FR 23801 - North American Electric Reliability Corporation; Order Approving Reliability Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-28

    ... primary control functionality. Nonetheless, until data from drills, exercises and tests can support a... control center becomes inoperable and to conduct reviews and tests, at least annually, to ensure viability... Preparedness and Operations (EOP) Reliability Standard EOP- 008-1 (Loss of Control Center Functionality). The...

  9. Preliminary Investigation of Time Remaining Display on the Computer-based Emergency Operating Procedure

    NASA Astrophysics Data System (ADS)

    Suryono, T. J.; Gofuku, A.

    2018-02-01

    One of the important thing in the mitigation of accidents in nuclear power plant accidents is time management. The accidents should be resolved as soon as possible in order to prevent the core melting and the release of radioactive material to the environment. In this case, operators should follow the emergency operating procedure related with the accident, in step by step order and in allowable time. Nowadays, the advanced main control rooms are equipped with computer-based procedures (CBPs) which is make it easier for operators to do their tasks of monitoring and controlling the reactor. However, most of the CBPs do not include the time remaining display feature which informs operators of time available for them to execute procedure steps and warns them if the they reach the time limit. Furthermore, the feature will increase the awareness of operators about their current situation in the procedure. This paper investigates this issue. The simplified of emergency operating procedure (EOP) of steam generator tube rupture (SGTR) accident of PWR plant is applied. In addition, the sequence of actions on each step of the procedure is modelled using multilevel flow modelling (MFM) and influenced propagation rule. The prediction of action time on each step is acquired based on similar case accidents and the Support Vector Regression. The derived time will be processed and then displayed on a CBP user interface.

  10. Source positions from VLBI combined solution

    NASA Astrophysics Data System (ADS)

    Bachmann, S.; Thaller, D.; Engelhardt, G.

    2014-12-01

    The IVS Combination Center at BKG is primarily responsible for combined Earth Orientation Parameter (EOP) products and the generation of a terrestrial reference frame based on VLBI observations (VTRF). The procedure is based on the combination of normal equations provided by six IVS Analysis Centers (AC). Since more and more ACs also provide source positions in the normal equations - beside EOPs and station coordinates - an estimation of these parameters is possible and should be investigated. In the past, the International Celestial Reference Frame (ICRF) was not generated as a combined solution from several individual solutions, but was based on a single solution provided by one AC. The presentation will give an overview on the combination strategy and the possibilities for combined source position determination. This includes comparisons with existing catalogs, quality estimation and possibilities of rigorous combination of EOP, TRF and CRF in one combination process.

  11. Improvement of VLBI EOP Accuracy and Precision

    NASA Technical Reports Server (NTRS)

    MacMillan, Daniel; Ma, Chopo

    2000-01-01

    In the CORE program, EOP measurements will be made with several different networks, each operating on a different day. It is essential that systematic differences between EOP derived by the different networks be minimized. Observed biases between the simultaneous CORE-A and NEOS-A sessions are about 60-130 micro(as) for PM, UT1 and nutation parameters. After removing biases, the observed rms differences are consistent with an increase in the formal precision of the measurements by factors ranging from 1.05 to 1.4. We discuss the possible sources of unmodeled error that account for these factors and the biases and the sensitivities of the network differences to modeling errors. We also discuss differences between VLBI and GPS PM measurements.

  12. Electro-optical parameters of bond polarizability model for aluminosilicates.

    PubMed

    Smirnov, Konstantin S; Bougeard, Daniel; Tandon, Poonam

    2006-04-06

    Electro-optical parameters (EOPs) of bond polarizability model (BPM) for aluminosilicate structures were derived from quantum-chemical DFT calculations of molecular models. The tensor of molecular polarizability and the derivatives of the tensor with respect to the bond length are well reproduced with the BPM, and the EOPs obtained are in a fair agreement with available experimental data. The parameters derived were found to be transferable to larger molecules. This finding suggests that the procedure used can be applied to systems with partially ionic chemical bonds. The transferability of the parameters to periodic systems was tested in molecular dynamics simulation of the polarized Raman spectra of alpha-quartz. It appeared that the molecular Si-O bond EOPs failed to reproduce the intensity of peaks in the spectra. This limitation is due to large values of the longitudinal components of the bond polarizability and its derivative found in the molecular calculations as compared to those obtained from periodic DFT calculations of crystalline silica polymorphs by Umari et al. (Phys. Rev. B 2001, 63, 094305). It is supposed that the electric field of the solid is responsible for the difference of the parameters. Nevertheless, the EOPs obtained can be used as an initial set of parameters for calculations of polarizability related characteristics of relevant systems in the framework of BPM.

  13. IVS contribution to the next ITRF

    NASA Astrophysics Data System (ADS)

    Bachmann, Sabine; Messerschmitt, Linda; Thaller, Daniela

    2015-04-01

    Generating the contribution of the International VLBI Service (IVS) to the next ITRF (ITRF2013 or ITRF2014) was the main task of the IVS Combination Center at the Federal Agency for Cartography and Geodesy (BKG, Germany) in 2014. Starting with the ITRF2005, the IVS contribution to the ITRF is an intra-technique combined solution using multiple individual contributions from different institutions. For the upcoming ITRF ten international institutions submitted data files for a combined solution. The data files contain 24h VLBI sessions from the late 1970s until the end of 2014 in SINEX file format containing datum free normal equations with station coordinates and Earth Orientation Parameters (EOP). All contributions have to meet the IVS standards for ITRF contribution in order to guarantee a consistent combined solution. In the course of the generation of the intra-technique combined solution, station coordinate time series for each station as well as a Terrestrial Reference Frame based on the contributed VLBI data (VTRF) were generated and analyzed. Preliminary results using data until the end of 2013 show a scaling factor of -0.47 ppb resulting from a 7-parameter Helmert transformation of the VTRF w.r.t. ITRF2008, which is comparable to the scaling factor that was determined in the precedent ITRF generation. An internal comparison of the EOPs between the combined solution and the individual contributions as well as external comparisons of the EOP series were carried out in order to assure a consistent quality of the EOPs. The data analyses, the combination procedure and results of the combined solution for station coordinates and EOP will be presented.

  14. Chemical composition, immunostimulatory, cytotoxic and antiparasitic activities of the essential oil from Brazilian red propolis

    PubMed Central

    das Neves, Raquel Nascimento; de Pinho, Rodrigo Barros; Silva, Mara Thais de Oliveira; Savegnago, Lucielli; Collares, Tiago; Seixas, Fabiana; Begnini, Karine; Henriques, João Antonio Pêgas; Ely, Mariana Roesch; Rufatto, Luciane C.; Moura, Sidnei; Barcellos, Thiago; Padilha, Francine; Dellagostin, Odir; Borsuk, Sibele

    2018-01-01

    Most studies of Brazilian red propolis have explored the composition and biological properties of its ethanolic extracts. In this work, we chemically extracted and characterized the essential oil of Brazilian red propolis (EOP) and assessed its adjuvant, antiparasitic and cytotoxic activities. The chemical composition of EOP was analyzed using gas chromatography with mass spectrometry (GC-MS). EOP was tested for in vitro activity against Trichomonas vaginalis (ATCC 30236 isolate); trophozoites were treated with different concentrations of EOP (ranging from 25 to 500 μg/mL) in order to establish the MIC and IC50 values. A cytotoxicity assay was performed in CHO-K1 cells submitted to different EOP concentrations. BALB/c mice were used to test the adjuvant effect of EOP. The animals were divided in 3 groups and inoculated as follows: 0.4 ng/kg BW EOP (G1); 50 μg of rCP40 protein (G2); or a combination of 0.4 ng/kg BW EOP and 50 μg of rCP40 (G3). Total IgG, IgG1 and IgG2a levels were assessed by ELISA. The major constituent compounds of EOP were methyl eugenol (13.1%), (E)-β-farnesene (2.50%), and δ-amorphene (2.3%). Exposure to EOP inhibited the growth of T. vaginalis, with an IC50 value of 100 μg/mL of EOP. An EOP concentration of 500 μg/mL was able to kill 100% of the T. vaginalis trophozoites. The EOP kinetic growth curve showed a 36% decrease in trophozoite growth after a 12 h exposure to 500 μg/mL of EOP, while complete parasite death was induced at 24 h. With regard to CHO-K1 cells, the CC50 was 266 μg/mL, and 92% cytotoxicity was observed after exposure to 500 μg/mL of EOP. Otherwise, a concentration of 200 μg/mL of EOP was able to reduce parasite proliferation by 70% and was not cytotoxic to CHO-K1 cells. As an adjuvant, a synergistic effect was observed when EOP was combined with the rCP40 protein (G3) in comparison to the administration of each component alone (G1 and G2), resulting in higher concentrations of IgG, IgG1 and IgG2a. EOP is constituted by biologically active components with promising antiparasitic and immunostimulatory activities and can be investigated for the formulation of new vaccines or trichomonacidal drugs. PMID:29390009

  15. Chemical composition, immunostimulatory, cytotoxic and antiparasitic activities of the essential oil from Brazilian red propolis.

    PubMed

    Sena-Lopes, Ângela; Bezerra, Francisco Silvestre Brilhante; das Neves, Raquel Nascimento; de Pinho, Rodrigo Barros; Silva, Mara Thais de Oliveira; Savegnago, Lucielli; Collares, Tiago; Seixas, Fabiana; Begnini, Karine; Henriques, João Antonio Pêgas; Ely, Mariana Roesch; Rufatto, Luciane C; Moura, Sidnei; Barcellos, Thiago; Padilha, Francine; Dellagostin, Odir; Borsuk, Sibele

    2018-01-01

    Most studies of Brazilian red propolis have explored the composition and biological properties of its ethanolic extracts. In this work, we chemically extracted and characterized the essential oil of Brazilian red propolis (EOP) and assessed its adjuvant, antiparasitic and cytotoxic activities. The chemical composition of EOP was analyzed using gas chromatography with mass spectrometry (GC-MS). EOP was tested for in vitro activity against Trichomonas vaginalis (ATCC 30236 isolate); trophozoites were treated with different concentrations of EOP (ranging from 25 to 500 μg/mL) in order to establish the MIC and IC50 values. A cytotoxicity assay was performed in CHO-K1 cells submitted to different EOP concentrations. BALB/c mice were used to test the adjuvant effect of EOP. The animals were divided in 3 groups and inoculated as follows: 0.4 ng/kg BW EOP (G1); 50 μg of rCP40 protein (G2); or a combination of 0.4 ng/kg BW EOP and 50 μg of rCP40 (G3). Total IgG, IgG1 and IgG2a levels were assessed by ELISA. The major constituent compounds of EOP were methyl eugenol (13.1%), (E)-β-farnesene (2.50%), and δ-amorphene (2.3%). Exposure to EOP inhibited the growth of T. vaginalis, with an IC50 value of 100 μg/mL of EOP. An EOP concentration of 500 μg/mL was able to kill 100% of the T. vaginalis trophozoites. The EOP kinetic growth curve showed a 36% decrease in trophozoite growth after a 12 h exposure to 500 μg/mL of EOP, while complete parasite death was induced at 24 h. With regard to CHO-K1 cells, the CC50 was 266 μg/mL, and 92% cytotoxicity was observed after exposure to 500 μg/mL of EOP. Otherwise, a concentration of 200 μg/mL of EOP was able to reduce parasite proliferation by 70% and was not cytotoxic to CHO-K1 cells. As an adjuvant, a synergistic effect was observed when EOP was combined with the rCP40 protein (G3) in comparison to the administration of each component alone (G1 and G2), resulting in higher concentrations of IgG, IgG1 and IgG2a. EOP is constituted by biologically active components with promising antiparasitic and immunostimulatory activities and can be investigated for the formulation of new vaccines or trichomonacidal drugs.

  16. VLBI real-time analysis by Kalman Filtering

    NASA Astrophysics Data System (ADS)

    Karbon, M.; Nilsson, T.; Soja, B.; Heinkelmann, R.; Raposo-Pulido, V.; Schuh, H.

    2013-12-01

    Geodetic Very Long Baseline Interferometry (VLBI) is one of the primary space geodetic techniques providing the full set of Earth Orientation Parameter (EOP) and is unique for observing long term Universal Time (UT1) and precession/nutation. Accurate and continuous EOP obtained in near real-time are essential for satellite based navigation and positioning and for enabling the precise tracking of interplanetary spacecrafts. To meet this necessity the International VLBI Service for Geodesy and Astrometry (IVS) increased its efforts to reduce the time span between the VLBI observations and the availability of the final results. Currently the timeliness is about two weeks, but the goal is to reduce it to less than one day with the future VGOS (VLBI2010 Global Observing System) network. The FWF project VLBI-ART contributes to this new generation VLBI system by considerably accelerating the VLBI analysis procedure through the implementation of an elaborate Kalman filter. This true real-time Kalman filter will be embedded in the Vienna VLBI Software (VieVS) as a completely automated tool with no need of human interaction. This filter also allows the prediction and combination of EOP from various space geodetic techniques by implementing stochastic models to statistically account for unpredictable changes in EOP. Additionally, atmospheric angular momenta calculated from numerical weather prediction models are introduced to support the short-term EOP prediction. To optimize the performance of the new software various investigations with real as well as simulated data are foreseen. The results are compared to the ones obtained by conventional VLBI parameter estimation methods (e.g. least squares method) and to corresponding parameter series from other techniques, such as from the Global Navigation Satellite Systems (GNSS).

  17. UTC(SU) and EOP(SU) - the only legal reference frames of Russian Federation

    NASA Astrophysics Data System (ADS)

    Koshelyaevsky, Nikolay B.; Blinov, Igor Yu; Pasynok, Sergey L.

    2015-08-01

    There are two legal time reference frames in Russian Federation. UTC(SU) deals with atomic time and play a role of reference for legal timing through the whole country. The other one, EOP(SU), deals with Earth's orientation parameters and provides the official EOP data for scientific, technical and metrological applications in Russia.The atomic time is based on two essential hardware components: primary Cs fountain standards and ensemble of continuously operating H-masers as a time unit/time scale keeper. Basing on H-maser intercomparison system data, regular H-maser frequency calibration against Cs standards and time algorithm autonomous TA(SU) time scale is maintained by the Main Metrological Center. Since 2013 time unit in TA(SU) is the second (SU) reproduced independently by VNIIFTRI Cs primary standards in accordance to it’s definition in the SI. UTC(SU) is relied on TA(SU) and steering to UTC basing on TWSTFT/GNSS time link data. As a result TA(SU) stability level relative to TT considerably exceeds 1×10-15 for sample time one month and more, RMS[UTC-UTC(SU)] ≤ 3 ns for the period of 2013-2015. UTC(SU) is broadcasted by different national means such as specialized radio and TV stations, NTP servers and GLONASS. Signals of Russian radio stations contains DUT1 and dUT1 values at 0.1s and 0.02s resolution respectively.The definitive EOP(SU) are calculated by the Main Metrological Center basing on composition of the eight independent individual EOP data streams delivered by four Russian analysis centers: VNIIFTRI, Institute of Applied Astronomy, Information-Analytical Center of Russian Space Agency and Analysis Center of Russian Space Agency. The accuracy of ultra-rapid EOP values for 2014 is estimated ≤ 0.0006" for polar motion, ≤ 70 microseconds for UT1-UTC and ≤ 0.0003" for celestial pole offsets respectively.The other VNIIFTRI EOP activities can be grouped in three basic directions:- arrangement and carrying out GNSS and SLR observations at five institutes- processing GNSS, SLR and VLBI observation data for EOP evaluation- combination of GLONASS satellites orbit/clocks.The paper will deliver more detailed and particular information on Russian legal reference frames.

  18. Using prospective hazard analysis to assess an active shooter emergency operations plan.

    PubMed

    Card, Alan J; Harrison, Heidi; Ward, James; Clarkson, P John

    2012-01-01

    Most risk management activity in the healthcare sector is retrospective, based on learning from experience. This is feasible where the risks are routine, but emergency operations plans (EOP) guide the response to events that are both high risk and rare. Under these circumstances, it is important to get the response right the first time, but learning from experience is usually not an option. This case study presents the rationale for taking a proactive approach to improving healthcare organizations' EOP. It demonstrates how the Prospective Hazard Analysis (PHA) Toolkit can drive organizational learning and argues that this toolkit may lead to more efficient improvement than drills and exercises. © 2012 American Society for Healthcare Risk Management of the American Hospital Association.

  19. The power of simplification: Operator interface with the AP1000{sup R} during design-basis and beyond design-basis events

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, M. G.; Mouser, M. R.; Simon, J. B.

    2012-07-01

    The AP1000{sup R} plant is an 1100-MWe pressurized water reactor with passive safety features and extensive plant simplifications that enhance construction, operation, maintenance, safety and cost. The passive safety features are designed to function without safety-grade support systems such as component cooling water, service water, compressed air or HVAC. The AP1000 passive safety features achieve and maintain safe shutdown in case of a design-basis accident for 72 hours without need for operator action, meeting the expectations provided in the European Utility Requirements and the Utility Requirement Document for passive plants. Limited operator actions may be required to maintain safe conditionsmore » in the spent fuel pool (SFP) via passive means. This safety approach therefore minimizes the reliance on operator action for accident mitigation, and this paper examines the operator interaction with the Human-System Interface (HSI) as the severity of an accident increases from an anticipated transient to a design basis accident and finally, to a beyond-design-basis event. The AP1000 Control Room design provides an extremely effective environment for addressing the first 72 hours of design-basis events and transients, providing ease of information dissemination and minimal reliance upon operator actions. Symptom-based procedures including Emergency Operating Procedures (EOPs), Abnormal Operating Procedures (AOPs) and Alarm Response Procedures (ARPs) are used to mitigate design basis transients and accidents. Use of the Computerized Procedure System (CPS) aids the operators during mitigation of the event. The CPS provides cues and direction to the operators as the event progresses. If the event becomes progressively worse or lasts longer than 72 hours, and depending upon the nature of failures that may have occurred, minimal operator actions may be required outside of the control room in areas that have been designed to be accessible using components that have been designed to be reliable in these conditions. The primary goal of any such actions is to maintain or refill the passive inventory available to cool the core, containment and spent fuel pool in the safety-related and seismically qualified Passive Containment Cooling Water Storage Tank (PCCWST). The seismically-qualified, ground-mounted Passive Containment Cooling Ancillary Water Storage Tank (PCCAWST) is also available for this function as appropriate. The primary effect of these actions would be to increase the coping time for the AP1000 during design basis events, as well as events such as those described above, from 72 hours without operator intervention to 7 days with minimal operator actions. These Operator actions necessary to protect the health and safety of the public are addressed in the Post-72 Hour procedures, as well as some EOPs, AOPs, ARPs and the Severe Accident Management Guidelines (SAMGs). Should the event continue to become more severe and plant conditions degrade further with indications of inadequate core cooling, the SAMGs provide guidance for strategies to address these hypothetical severe accident conditions. The AP1000 SAMG diagnoses and actions are prioritized to first utilize the AP1000 features that are expected to retain a damaged core inside the reactor vessel. Only one strategy is undertaken at any time. This strategy will be followed and its effectiveness evaluated before other strategies are undertaken. This is a key feature of both the symptom-oriented AP1000 EOPs and the AP1000 SAMGs which maximizes the probability of retaining a damaged core inside the reactor vessel and containment while minimizing the chances for confusion and human errors during implementation. The AP1000 SAMGs are simple and straight-forward and have been developed with considerable input from human factors and plant operations experts. Most importantly, and different from severe accident management strategies for other plants, the AP1000 SAMGs do not require diagnosis of the location of the core (i.e., whether reactor vessel failure has occurred). This is a fundamental consequence of the AP1000 In-Vessel Retention approach, which allows severe accident management to be based on fundamental principles (e.g. provide coolant as close as possible to the core) that do not change during a specific event. This eliminates the need for one of the more difficult diagnostic requirements, since reactor vessel failure does not directly relate to any measurable plant parameter, and differs from other designs in that an engineered failure of the pressure vessel' (e.g. core catcher) is never required. (authors)« less

  20. The Feasibility of 3d Point Cloud Generation from Smartphones

    NASA Astrophysics Data System (ADS)

    Alsubaie, N.; El-Sheimy, N.

    2016-06-01

    This paper proposes a new technique for increasing the accuracy of direct geo-referenced image-based 3D point cloud generated from low-cost sensors in smartphones. The smartphone's motion sensors are used to directly acquire the Exterior Orientation Parameters (EOPs) of the captured images. These EOPs, along with the Interior Orientation Parameters (IOPs) of the camera/ phone, are used to reconstruct the image-based 3D point cloud. However, because smartphone motion sensors suffer from poor GPS accuracy, accumulated drift and high signal noise, inaccurate 3D mapping solutions often result. Therefore, horizontal and vertical linear features, visible in each image, are extracted and used as constraints in the bundle adjustment procedure. These constraints correct the relative position and orientation of the 3D mapping solution. Once the enhanced EOPs are estimated, the semi-global matching algorithm (SGM) is used to generate the image-based dense 3D point cloud. Statistical analysis and assessment are implemented herein, in order to demonstrate the feasibility of 3D point cloud generation from the consumer-grade sensors in smartphones.

  1. Researches on High Accuracy Prediction Methods of Earth Orientation Parameters

    NASA Astrophysics Data System (ADS)

    Xu, X. Q.

    2015-09-01

    The Earth rotation reflects the coupling process among the solid Earth, atmosphere, oceans, mantle, and core of the Earth on multiple spatial and temporal scales. The Earth rotation can be described by the Earth's orientation parameters, which are abbreviated as EOP (mainly including two polar motion components PM_X and PM_Y, and variation in the length of day ΔLOD). The EOP is crucial in the transformation between the terrestrial and celestial reference systems, and has important applications in many areas such as the deep space exploration, satellite precise orbit determination, and astrogeodynamics. However, the EOP products obtained by the space geodetic technologies generally delay by several days to two weeks. The growing demands for modern space navigation make high-accuracy EOP prediction be a worthy topic. This thesis is composed of the following three aspects, for the purpose of improving the EOP forecast accuracy. (1) We analyze the relation between the length of the basic data series and the EOP forecast accuracy, and compare the EOP prediction accuracy for the linear autoregressive (AR) model and the nonlinear artificial neural network (ANN) method by performing the least squares (LS) extrapolations. The results show that the high precision forecast of EOP can be realized by appropriate selection of the basic data series length according to the required time span of EOP prediction: for short-term prediction, the basic data series should be shorter, while for the long-term prediction, the series should be longer. The analysis also showed that the LS+AR model is more suitable for the short-term forecasts, while the LS+ANN model shows the advantages in the medium- and long-term forecasts. (2) We develop for the first time a new method which combines the autoregressive model and Kalman filter (AR+Kalman) in short-term EOP prediction. The equations of observation and state are established using the EOP series and the autoregressive coefficients respectively, which are used to improve/re-evaluate the AR model. Comparing to the single AR model, the AR+Kalman method performs better in the prediction of UT1-UTC and ΔLOD, and the improvement in the prediction of the polar motion is significant. (3) Following the successful Earth Orientation Parameter Prediction Comparison Campaign (EOP PCC), the Earth Orientation Parameter Combination of Prediction Pilot Project (EOPC PPP) was sponsored in 2010. As one of the participants from China, we update and submit the short- and medium-term (1 to 90 days) EOP predictions every day. From the current comparative statistics, our prediction accuracy is on the medium international level. We will carry out more innovative researches to improve the EOP forecast accuracy and enhance our level in EOP forecast.

  2. Staphylococcus aureus carriage at admission predicts early-onset pneumonia after burn trauma.

    PubMed

    Fournier, A; Voirol, P; Krähenbühl, M; Bonnemain, C-L; Fournier, C; Dupuis-Lozeron, E; Pantet, O; Pagani, J-L; Revelly, J-P; Sadeghipour, F; Eggimann, P; Que, Y-A

    2017-03-01

    Early-onset pneumonia (EOP) is frequent after burn trauma, increasing morbidity in the critical resuscitation phase, which may preclude early aggressive management of burn wounds. Currently, however, preemptive treatment is not recommended. The aim of this study was to identify predictive factors for EOP that may justify early empirical antibiotic treatment. Data for all burn patients requiring ≥4 h mechanical ventilation (MV) who were admitted between January 2001 and October 2012 were extracted from the hospital's computerized information system. We reviewed EOP episodes (≤7 days) among patients who underwent endotracheal aspiration (ETA) within 5 days after admission. Univariate and multivariate analyses were performed to identify independent factors associated with EOP. Logistic regression was used to identify factors predicting EOP development. During the study period, 396 burn patients were admitted. ETA was performed within 5 days in 204/290 patients receiving ≥4 h MV. One hundred and eight patients developed EOP; 47 cases were caused by Staphylococcus aureus, 37 by Haemophilus influenzae, and 23 by Streptococcus pneumoniae. Among the 33 patients showing S. aureus positivity on ETA samples, 16 (48.5 %) developed S. aureus EOP. Among the 156 S. aureus non-carriers, 16 (10.2 %) developed EOP. Staphylococcus aureus carriage independently predicted EOP (p < 0.0001). We identified S. aureus carriage as an independent and strong predictor of EOP. As rapid point-of-care testing for S. aureus is readily available, we recommend testing of all patients at admission for burn trauma and the consideration of early preemptive treatment in all positive patients. Further studies are needed to evaluate this new strategy.

  3. The effects of sildenafil citrate on urinary podocin and nephrin mRNA expression in an L-NAME model of pre-eclampsia.

    PubMed

    Baijnath, Sooraj; Murugesan, Saravanakumar; Mackraj, Irene; Gathiram, Prem; Moodley, Jagidesa

    2017-03-01

    We investigated the effects of sildenafil citrate (SC) on podocyturia in N ω -nitro-L-arginine methyl ester hydrochloride (L-NAME) model of pre-eclampsia (PE). One hundred and twenty Sprague-Dawley rats (SDR) were divided into five groups like pregnant control (PC), early-onset PE (EOPE), late-onset PE(LOPE), early and late-onset PE with SC-treated groups [EOPE (SC); LOPE (SC)]. PE was induced in SDR by oral administration of L-NAME in drinking water for 4-8 days for EOPE and 8-14 day for LOPE. The blood pressure, urine volume and total urine protein were increased in EOPE and LOPE groups when compared to PC, and all the above parameters decreased in EOPE (SC) and LOPE (SC) groups when compared to EOPE and LOPE groups, respectively. The EOPE and LOPE groups showed an increase in urinary nephrin mRNA and podocin mRNA levels compared to PC group. Increases in serum and renal soluble fms-like tyrosine kinase-1 (sFlt-1) expression levels and decreases in renal vascular endothelial growth factor (VEGF) expression and serum placenta growth factor (PlGF) levels were observed in EOPE and LOPE groups when compared to PC group. In addition, decreases in serum and renal sFlt-1 expression levels and increases in renal VEGF expression and serum PlGF levels were observed in EOPE (SC) and LOPE (SC) groups when compared to EOPE and LOPE groups, respectively. The light microscopy showed that the renal tissue of L-NAME-treated rats had extensive glomerular damage, tubular damage and infiltration by mononuclear cells when compared to PC group. Therefore, SC ameliorated podocyturia through its effects on the antiangiogenic/angiogenic status in this animal model.

  4. Evaluation of maternal serum hypoxia inducible factor-1α, progranulin and syndecan-1 levels in pregnancies with early- and late-onset preeclampsia.

    PubMed

    Alici Davutoğlu, Ebru; Akkaya Firat, Asuman; Ozel, Ayşegül; Yılmaz, Nevin; Uzun, Isil; Temel Yuksel, Ilkbal; Madazlı, Riza

    2018-08-01

    To determine the serum levels of HIF-1 α, progranulin, and syndecan-1 in preeclampsia (PE) and normal pregnancy, and to compare whether these markers demonstrate any difference between early-onset PE (EO-PE) and late-onset PE (LO-PE). This cross-sectional study was conducted on 27 women with EO-PE, 27 women with LO-PE, and 26 healthy normotensive pregnant controls matched for gestational age. Maternal levels of serum HIF-1 α, progranulin, and syndecan-1 were measured with the use of an enzyme-linked immunosorbent assay kit. Statistical analysis revealed significant differences between the control and the PE groups in progranulin (p < .001) and syndecan-1 (p <.001) levels. There were no significant differences in the serum HIF-1 α levels between these groups (p= .069). When PE patients were evaluated by considering subgroups; statistical analysis revealed significant inter-group differences in all biomarkers. Serum progranulin levels were significantly higher in LO-PE compared with the other two groups (EO-PE versus LO-PE and LO-PE versus controls p = .000). Control group presented significantly higher syndecan-1 levels, than EO and LO-PE (p < .001). HIF-1 α levels positively correlated with progranulin levels (r = .439, p= .000). Serum progranulin may have potential to be used as a biomarker for the differentiation of EO-PE and LO-PE. The co-operative action between HIF-1 α and progranulin might play a key role in the pathogenesis of LO-PE. The predominant feature of LO-PE seems to be an inflammatory process, whereas in EO-PE placentation problem seems to be the main pathology.

  5. Stacking open-capillary electroosmotic pumps in series to boost the pumping pressure to drive high-performance liquid chromatographic separations.

    PubMed

    He, Chiyang; Zhu, Zaifang; Gu, Congying; Lu, Joann; Liu, Shaorong

    2012-03-02

    Numerous micropumps have been developed, but few of them can produce adequate flow rate and pressure for high-performance liquid chromatography (HPLC) applications. We have recently developed an innovative hybrid electroosmotic pump (EOP) to solve this problem. The basic unit of a hybrid pump consists of a +EOP (the pumping element is positively charged) and a -EOP (the pumping element is negatively charged). The outlet of the +EOP is then joined with the inlet of the -EOP, forming a basic pump unit, while the anode of a positive high voltage (HV) power supply is placed at the joint. The inlet and outlet of this pump unit are electrically grounded. With this configuration, we can stack many of such pump units in series to boost the pumping power. In this work, we describe in details how an open-capillary hybrid EOP is constructed and characterize this pump systematically. We also show that a hybrid EOP with ten serially stacked pump units can deliver a maximum pressure of 21.5 MPa (∼3100 psi). We further demonstrate the feasibility of using this hybrid EOP to drive eluents for HPLC separations of proteins and peptides. Copyright © 2012 Elsevier B.V. All rights reserved.

  6. Stacking open-capillary electroosmotic pumps in series to boost the pumping pressure to drive high-performance liquid chromatographic separations

    DOE PAGES

    He, Chiyang; Zhu, Zaifang; Gu, Congying; ...

    2012-01-09

    Numerous micropumps have been developed, but few of them can produce adequate flow rate and pressure for high-performance liquid chromatography (HPLC) applications. We have recently developed an innovative hybrid electroosmotic pump (EOP) to solve this problem. The basic unit of a hybrid pump consists of a +EOP (the pumping element is positively charged) and a -EOP (the pumping element is negatively charged). The outlet of the +EOP is then joined with the inlet of the -EOP, forming a basic pump unit, while the anode of a positive high voltage (HV) power supply is placed at the joint. The inlet andmore » outlet of this pump unit are electrically grounded. With this configuration, we can stack many of such pump units in series to boost the pumping power. In this work, we describe in details how an open-capillary hybrid EOP is constructed and characterize this pump systematically. We also show that a hybrid EOP with ten serially stacked pump units can deliver a maximum pressure of 21.5 MPa (~3100 psi). Here, we further demonstrate the feasibility of using this hybrid EOP to drive eluents for HPLC separations of proteins and peptides.« less

  7. Eop1 from a Rubus strain of Erwinia amylovora functions as a host-range limiting factor.

    PubMed

    Asselin, J E; Bonasera, J M; Kim, J F; Oh, C-S; Beer, S V

    2011-08-01

    Strains of Erwinia amylovora, the bacterium causing the disease fire blight of rosaceous plants, are separated into two groups based on host range: Spiraeoideae and Rubus strains. Spiraeoideae strains have wide host ranges, infecting plants in many rosaceous genera, including apple and pear. In the field, Rubus strains infect the genus Rubus exclusively, which includes raspberry and blackberry. Based on comparisons of limited sequence data from a Rubus and a Spiraeoideae strain, the gene eop1 was identified as unusually divergent, and it was selected as a possible host specificity factor. To test this, eop1 genes from a Rubus strain and a Spiraeoideae strain were cloned and mutated. Expression of the Rubus-strain eop1 reduced the virulence of E. amylovora in immature pear fruit and in apple shoots. Sequencing the orfA-eop1 regions of several strains of E. amylovora confirmed that forms of eop1 are conserved among strains with similar host ranges. This work provides evidence that eop1 from a Rubus-specific strain can function as a determinant of host specificity in E. amylovora.

  8. Regulation of Effector Delivery by Type III Secretion Chaperone Proteins in Erwinia amylovora.

    PubMed

    Castiblanco, Luisa F; Triplett, Lindsay R; Sundin, George W

    2018-01-01

    Type III secretion (TTS) chaperones are critical for the delivery of many effector proteins from Gram-negative bacterial pathogens into host cells, functioning in the stabilization and hierarchical delivery of the effectors to the type III secretion system (TTSS). The plant pathogen Erwinia amylovora secretes at least four TTS effector proteins: DspE, Eop1, Eop3, and Eop4. DspE specifically interacts with the TTS chaperone protein DspF, which stabilizes the effector protein in the cytoplasm and promotes its efficient translocation through the TTSS. However, the role of E. amylovora chaperones in regulating the delivery of other secreted effectors is unknown. In this study, we identified functional interactions between the effector proteins DspE, Eop1, and Eop3 with the TTS chaperones DspF, Esc1 and Esc3 in yeast. Using site-directed mutagenesis, secretion, and translocation assays, we demonstrated that the three TTS chaperones have additive roles for the secretion and translocation of DspE into plant cells whereas DspF negatively affects the translocation of Eop1 and Eop3. Collectively, these results indicate that TTS chaperone proteins exhibit a cooperative behavior to orchestrate the effector secretion and translocation dynamics in E. amylovora .

  9. A Strategic Independent Geodetic VLBI Network for Europe

    NASA Astrophysics Data System (ADS)

    Dale, Denise; Combrinck, Ludwig; de Witt, Alet

    2014-12-01

    Irregularities of the rotation of the Earth in space are described by the Earth Orientation Parameters (EOPs). An independent EOP network, applying the Very Long Baseline Interferometry (VLBI) technique and using the Vienna VLBI Software (VieVS), are strategically essential for Europe to minimize its reliance on foreign global support in terms of required infrastructure for the realization of such a network. The generation of independent EOPs is already achievable by countries such as the USA, the People's Republic of China, and the Russian Federation due to their large extent of land mass that allows for long baselines in both the North-South and East-West directions and thus allows for accurate determination of all EOPs. These three countries need not rely on foreign partnerships to generate EOPs, as they all have independent geodetic VLBI networks capable of determining EOPs for precise positioning, navigation, and satellite launch/orbital purposes. They also have or are developing independent Global Navigation Satellite Systems (GNSS) constellations; so does the European Union (EU). Accurate EOPs are essential for long-term orbital maintenance of GNSS constellations, leaving the EU GALILEO GNSS vulnerable and reliant on the three superpowers. Generation of accurate EOPs by Europe is not possible due to its much smaller land mass and thus smaller achievable baselines. Even though there are many radio telescopes spread across Europe, these are separated by relatively short distances. The proposed stations that will be used to investigate this independent EOP network for Europe are the WETTZELL radio telescope in Germany, two German owned radio telescopes, TIGOCONC in Concepción, Chile, and OHIGGINS in Antarctica, as well as the HartRAO radio telescope in South Africa.

  10. Electroosmotic pumps and their applications in microfluidic systems

    PubMed Central

    Wang, Xiayan; Cheng, Chang; Wang, Shili; Liu, Shaorong

    2009-01-01

    Electroosmotic pumping is receiving increasing attention in recent years owing to the rapid development in micro total analytical systems. Compared with other micropumps, electroosmotic pumps (EOPs) offer a number of advantages such as creation of constant pulse-free flows and elimination of moving parts. The flow rates and pumping pressures of EOPs matches well with micro analysis systems. The common materials and fabrication technologies make it readily integrateable with lab-on-a-chip devices. This paper reviews the recent progress on EOP fabrications and applications in order to promote the awareness of EOPs to researchers interested in using micro- and nano-fluidic devices. The pros and cons of EOPs are also discussed, which helps these researchers in designing and constructing their micro platforms. PMID:20126306

  11. A Comparison of Five Numerical Weather Prediction Analysis Climatologies in Southern High Latitudes.

    NASA Astrophysics Data System (ADS)

    Connolley, William M.; Harangozo, Stephen A.

    2001-01-01

    In this paper, numerical weather prediction analyses from four major centers are compared-the Australian Bureau of Meteorology (ABM), the European Centre for Medium-Range Weather Forecasts (ECMWF), the U.S. National Centers for Environmental Prediction-National Center for Atmospheric Research (NCEP-NCAR), and The Met. Office (UKMO). Two of the series-ECMWF reanalysis (ERA) and NCEP-NCAR reanalysis (NNR)-are `reanalyses'; that is, the data have recently been processed through a consistent, modern analysis system. The other three-ABM, ECMWF operational (EOP), and UKMO-are archived from operational analyses.The primary focus in this paper is on the period of 1979-93, the period used for the reanalyses, and on climatology. However, ABM and NNR are also compared for the period before 1979, for which the evidence tends to favor NNR. The authors are concerned with basic variables-mean sea level pressure, height of the 500-hPa surface, and near-surface temperature-that are available from the basic analysis step, rather than more derived quantities (such as precipitation), which are available only from the forecast step.Direct comparisons against station observations, intercomparisons of the spatial pattern of the analyses, and intercomparisons of the temporal variation indicate that ERA, EOP, and UKMO are best for sea level pressure;that UKMO and EOP are best for 500-hPa height; and that none of the analyses perform well for near-surface temperature.

  12. Application of the electroosmotic effect for thrust generation

    NASA Astrophysics Data System (ADS)

    Hansen, Thomas Edward

    The present work focuses on demonstrating the capabilities of electroosmotic pumps, (EOP) to generate thrust. An underwater glider was successfully propelled by electroosmosis for the first time published - at 0.85 inches per second. Asymmetric AC voltage pulsing proved to produce higher flow rates then equivalent DC pumps for the same average voltage. Ultra-short pulsing proved 100 nanosecond rise times in EOP are possible, which surpassed published predictions by three orders of magnitude. Theories behind efficiency losses of high power EOP were investigated. Direct measurement of effective voltage at the face of a membrane is the most accurate way to determine voltage drop across the electrolyte of an EOP. Forced convection lowered efficiency of the EOP for low voltages by preventing capacitance charging, but proved to prolong pump life during high power application.

  13. Ad Hoc working group on diurnal and semi-diurnal Earth Orientation variation.

    NASA Astrophysics Data System (ADS)

    Gipson, J. M.

    2017-12-01

    Diurnal and semi-diurnal Earth orientation ("HF-EOP") variation were detected in the early 1990s in SLR and VLBI data. Beginning in 1996 a model of HF-EOP variation based on ocean-tides derived from Topex data was included in the IERS standards. This model has not been updated since then with the exception of including libration for effects for polar motion (2003 IERS conventions) and UT1 (2010 IERS conventions). The accuracy of Space Geodesy has increased remarkably over the last 20 years and the 1996 IERS HF-EOP model is no longer adequate. At the conclusion of the 2017 GGOS/IERS Unified Analysis Workshop an ad hoc working group was formed including representatives of the IDS, IGS, ILRS, and IVS. The goal of the working group is to test several models of HF-EOP in the different space geodesy techniques and to make a recommendation to the IERS for the adoption of a new HF-EOP model. In this presentation I will give a summary of work on HF-EOP done to date by various scientists which demonstrate the inadequacy of the current IERS HF-EOP model. I will then describe the goals and the progress of the working group to date, with a preview of further work.

  14. Anatomical consideration of the occipital cutaneous nerves and artery for the safe treatment of occipital neuralgia.

    PubMed

    Shin, Kang-Jae; Kim, Hong-San; O, Jehoon; Kwon, Hyun-Jin; Yang, Hun-Mu

    2018-05-12

    There is no standardized approach to the greater occipital nerve (GON) block technique for treating occipital neuralgia. The aim of the present study was to validate the previously-suggested guidelines for conventional injection techniques and to provide navigational guidelines for safe GON block. The GON, lesser occipital nerve (LON) and occipital artery (OA) were carefully dissected in the occipital region of embalmed cadavers. Using a 3D digitizer, the GON, LON, and OA were observed on the two reference lines. The distances between the landmarks were recorded and statistically analyzed. On the superior nuchal line, the mean distances between the external occipital protuberance (EOP) and the most medial branch of the GON was 33.5 mm. The mean distance between the EOP and the most medial branch of the OA was 37.4 mm. On the EOP-mastoid process (MP) line, the GON was on the medial third and the LON the lateral third of the EOP-MP line. The safe injection points on the EOP-MP line are about 3 cm from the EOP, 1 cm inferior parallel to the EOP-MP line, and about 3 cm away from the MP. This article is protected by copyright. All rights reserved. © 2018 Wiley Periodicals, Inc.

  15. The consistency of the current conventional celestial and terrestrial reference frames and the conventional EOP series

    NASA Astrophysics Data System (ADS)

    Heinkelmann, R.; Belda-Palazon, S.; Ferrándiz, J.; Schuh, H.

    2015-08-01

    For applications in Earth sciences, navigation, and astronomy the celestial (ICRF) and terrestrial (ITRF) reference frames as well as the orientation among them, the Earth orientation parameters (EOP), have to be consistent at the level of 1 mm and 0.1 mm/yr (GGOS recommendations). We assess the effect of unmodelled geophysical signals in the regularized coordinates and the sensitivity with respect to different a priori EOP and celestial reference frames. The EOP are determined using the same VLBI data but with station coordinates fixed on different TRFs. The conclusion is that within the time span of data incorporated into ITRF2008 (Altamimi, et al., 2011) the ITRF2008 and the IERS 08 C04 are consistent. This consistency involves that non-linear station motion such as unmodelled geophysical signals partly affect the IERS 08 C04 EOP. There are small but not negligible inconsistencies between the conventional celestial reference frame, ICRF2 (Fey, et al., 2009), the ITRF2008 and the conventional EOP that are quantified by comparing VTRF2008 (Böckmann, et al., 2010) and ITRF2008.

  16. Numerical Algorithms for Precise and Efficient Orbit Propagation and Positioning

    NASA Astrophysics Data System (ADS)

    Bradley, Ben K.

    Motivated by the growing space catalog and the demands for precise orbit determination with shorter latency for science and reconnaissance missions, this research improves the computational performance of orbit propagation through more efficient and precise numerical integration and frame transformation implementations. Propagation of satellite orbits is required for astrodynamics applications including mission design, orbit determination in support of operations and payload data analysis, and conjunction assessment. Each of these applications has somewhat different requirements in terms of accuracy, precision, latency, and computational load. This dissertation develops procedures to achieve various levels of accuracy while minimizing computational cost for diverse orbit determination applications. This is done by addressing two aspects of orbit determination: (1) numerical integration used for orbit propagation and (2) precise frame transformations necessary for force model evaluation and station coordinate rotations. This dissertation describes a recently developed method for numerical integration, dubbed Bandlimited Collocation Implicit Runge-Kutta (BLC-IRK), and compare its efficiency in propagating orbits to existing techniques commonly used in astrodynamics. The BLC-IRK scheme uses generalized Gaussian quadratures for bandlimited functions. It requires significantly fewer force function evaluations than explicit Runge-Kutta schemes and approaches the efficiency of the 8th-order Gauss-Jackson multistep method. Converting between the Geocentric Celestial Reference System (GCRS) and International Terrestrial Reference System (ITRS) is necessary for many applications in astrodynamics, such as orbit propagation, orbit determination, and analyzing geoscience data from satellite missions. This dissertation provides simplifications to the Celestial Intermediate Origin (CIO) transformation scheme and Earth orientation parameter (EOP) storage for use in positioning and orbit propagation, yielding savings in computation time and memory. Orbit propagation and position transformation simulations are analyzed to generate a complete set of recommendations for performing the ITRS/GCRS transformation for a wide range of needs, encompassing real-time on-board satellite operations and precise post-processing applications. In addition, a complete derivation of the ITRS/GCRS frame transformation time-derivative is detailed for use in velocity transformations between the GCRS and ITRS and is applied to orbit propagation in the rotating ITRS. EOP interpolation methods and ocean tide corrections are shown to impact the ITRS/GCRS transformation accuracy at the level of 5 cm and 20 cm on the surface of the Earth and at the Global Positioning System (GPS) altitude, respectively. The precession-nutation and EOP simplifications yield maximum propagation errors of approximately 2 cm and 1 m after 15 minutes and 6 hours in low-Earth orbit (LEO), respectively, while reducing computation time and memory usage. Finally, for orbit propagation in the ITRS, a simplified scheme is demonstrated that yields propagation errors under 5 cm after 15 minutes in LEO. This approach is beneficial for orbit determination based on GPS measurements. We conclude with a summary of recommendations on EOP usage and bias-precession-nutation implementations for achieving a wide range of transformation and propagation accuracies at several altitudes. This comprehensive set of recommendations allows satellite operators, astrodynamicists, and scientists to make informed decisions when choosing the best implementation for their application, balancing accuracy and computational complexity.

  17. Consistent realization of Celestial and Terrestrial Reference Frames

    NASA Astrophysics Data System (ADS)

    Kwak, Younghee; Bloßfeld, Mathis; Schmid, Ralf; Angermann, Detlef; Gerstl, Michael; Seitz, Manuela

    2018-03-01

    The Celestial Reference System (CRS) is currently realized only by Very Long Baseline Interferometry (VLBI) because it is the space geodetic technique that enables observations in that frame. In contrast, the Terrestrial Reference System (TRS) is realized by means of the combination of four space geodetic techniques: Global Navigation Satellite System (GNSS), VLBI, Satellite Laser Ranging (SLR), and Doppler Orbitography and Radiopositioning Integrated by Satellite. The Earth orientation parameters (EOP) are the link between the two types of systems, CRS and TRS. The EOP series of the International Earth Rotation and Reference Systems Service were combined of specifically selected series from various analysis centers. Other EOP series were generated by a simultaneous estimation together with the TRF while the CRF was fixed. Those computation approaches entail inherent inconsistencies between TRF, EOP, and CRF, also because the input data sets are different. A combined normal equation (NEQ) system, which consists of all the parameters, i.e., TRF, EOP, and CRF, would overcome such an inconsistency. In this paper, we simultaneously estimate TRF, EOP, and CRF from an inter-technique combined NEQ using the latest GNSS, VLBI, and SLR data (2005-2015). The results show that the selection of local ties is most critical to the TRF. The combination of pole coordinates is beneficial for the CRF, whereas the combination of Δ UT1 results in clear rotations of the estimated CRF. However, the standard deviations of the EOP and the CRF improve by the inter-technique combination which indicates the benefits of a common estimation of all parameters. It became evident that the common determination of TRF, EOP, and CRF systematically influences future ICRF computations at the level of several μas. Moreover, the CRF is influenced by up to 50 μas if the station coordinates and EOP are dominated by the satellite techniques.

  18. Educational Opportunity Program (EOP) at a Selective Public University: Initial Findings from a Longitudinal Evaluation Study

    ERIC Educational Resources Information Center

    Winograd, Greta; Verkuilen, Jay; Weingarten, Alison; Walker, Lucy

    2018-01-01

    In this study, we examined academic outcomes among students from low-income and academically disadvantaged backgrounds who participated in the Educational Opportunity Program (EOP) at a selective four-year public comprehensive college in the Northeast. We found that provisionally admitted EOP students earned comparable first-semester grades and…

  19. EOP and scale from continuous VLBI observing: CONT campaigns to future VGOS networks

    NASA Astrophysics Data System (ADS)

    MacMillan, D. S.

    2017-07-01

    Continuous (CONT) VLBI campaigns have been carried out about every 3 years since 2002. The basic idea of these campaigns is to acquire state-of-the-art VLBI data over a continuous time period of about 2 weeks to demonstrate the highest accuracy of which the current VLBI system is capable. In addition, these campaigns support scientific studies such as investigations of high-resolution Earth rotation, reference frame stability, and daily to sub-daily site motions. The size of the CONT networks and the observing data rate have increased steadily since 1994. Performance of these networks based on reference frame scale precision and polar motion/LOD comparison with global navigation satellite system (GNSS) earth orientation parameters (EOP) has been substantially better than the weekly operational R1 and R4 series. The precisions of CONT EOP and scale have improved by more than a factor of two since 2002. Polar motion precision based on the WRMS difference between VLBI and GNSS for the most recent CONT campaigns is at the 30 μas level, which is comparable to that of GNSS. The CONT campaigns are a natural precursor to the planned future VLBI observing networks, which are expected to observe continuously. We compare the performance of the most recent CONT campaigns in 2011 and 2014 with the expected performance of the future VLBI global observing system network using simulations. These simulations indicate that the expected future precision of scale and EOP will be at least 3 times better than the current CONT precision.

  20. Ameliorating effects of ethyl acetate fraction from onion (Allium cepa L.) flesh and peel in mice following trimethyltin-induced learning and memory impairment.

    PubMed

    Park, Seon Kyeong; Jin, Dong Eun; Park, Chang Hyeon; Seung, Tae Wan; Guo, Tian Jiao; Song, Jong Wook; Kim, Jong Hwan; Kim, Dae Ok; Heo, Ho Jin

    2015-09-01

    The anti-amnesic effects of onion (Allium cepa L.) flesh (OF) 1 and peel (OP) 2 on trimethyltin (TMT) 3 -induced learning and memory dysfunction were investigated to confirm learning and memory function. The inhibitory effect against cellular acetylcholinesterase (AChE) 4 showed that the EtOAc fraction of OP (EOP 5 , IC 50 value=37.11μg/mL) was higher than the EtOAc fraction of OF (EOF 6 , IC 50 value=433.34μg/mL). The cognitive effects in ICR mice were also evaluated using Y-maze, passive avoidance, and Morris water maze tests. After the behavioral tests, AChE activity (control=100%, TMT=128%, EOF 20=108%, EOP 10=104%, and EOP 20=98%), superoxide dismutase (SOD) 7 activity, oxidized glutathione (GSSG) 8 /total glutathione (GSH) 9 and malondialdehyde (MDA) 10 production were examined. These results indicate that both EOF and EOP improved learning and memory function. The main compounds of the EOF and EOP were analyzed by Q-TOF UPLC/MS, and the results were as follows: The EOF (quercetin and quercetin-4'-glucoside) and the EOP (quercetin-4'-glucoside and isorhamnetin-4'-glucoside). Consequently, our results suggest that both EOF and EOP could be efficacious in improving cognitive function through AChE inhibition and antioxidant activity in mice brains. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Chemical composition, antinociceptive and anti-inflammatory effects in rodents of the essential oil of Peperomia serpens (Sw.) Loud.

    PubMed

    Pinheiro, B G; Silva, A S B; Souza, G E P; Figueiredo, J G; Cunha, F Q; Lahlou, S; da Silva, J K R; Maia, J G S; Sousa, P J C

    2011-11-18

    Peperomia serpens (Piperaceae), popularly known as "carrapatinho", is an epiphyte herbaceous liana grown wild on different host trees in the Amazon rainforest. Its leaves are largely used in Brazilian folk medicine to treat inflammation, pain and asthma. This study investigated the effects of essential oil of Peperomia serpens (EOPs) in standard rodent models of pain and inflammation. The antinociceptive activity was evaluated using chemical (acetic acid and formalin) and thermal (hot plate) models of nociception in mice whereas the anti-inflammatory activity was evaluated by carrageenan- and dextran-induced paw edema tests in rats croton oil-induced ear edema, as well as cell migration, rolling and adhesion induced by carrageenan in mice. Additionally, phytochemical analysis of the EOPs has been also performed. Chemical composition of the EOPs was analyzed by gas chromatography and mass spectrometry (GC/MS). Twenty-four compounds, representing 89.6% of total oil, were identified. (E)-Nerolidol (38.0%), ledol (27.1%), α-humulene (11.5%), (E)-caryophyllene (4.0%) and α-eudesmol (2.7%) were found to be the major constituents of the oil. Oral pretreatment with EOPs (62.5-500 mg/kg) significantly reduced the writhing number evoked by acetic acid injection, with an ED(50) value of 188.8 mg/kg that was used thereafter in all tests. EOPs had no significant effect on hot plate test but reduced the licking time in both phases of the formalin test, an effect that was not significantly altered by naloxone (0.4 mg/kg, s.c.). EOPs inhibited the edema formation induced by carrageenan and dextran in rats. In mice, EOPs inhibited the edema formation by croton oil as well as the leukocyte and neutrophil migration, the rolling and the adhesion of leukocytes. These data show for the first time that EOPs has a significant and peripheral antinociceptive effect that seems unrelated to interaction with the opioid system. EOPs also displays a significant anti-inflammatory effect in acute inflammation models. This effect seems to be related to components which inhibit the production of several inflammatory mediators. These results support the widespread use of Peperomia serpens in popular medicine to treat inflammation and pain. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  2. Extended output phasor representation of multi-spectral fluorescence lifetime imaging microscopy

    PubMed Central

    Campos-Delgado, Daniel U.; Navarro, O. Gutiérrez; Arce-Santana, E. R.; Jo, Javier A.

    2015-01-01

    In this paper, we investigate novel low-dimensional and model-free representations for multi-spectral fluorescence lifetime imaging microscopy (m-FLIM) data. We depart from the classical definition of the phasor in the complex plane to propose the extended output phasor (EOP) and extended phasor (EP) for multi-spectral information. The frequency domain properties of the EOP and EP are analytically studied based on a multiexponential model for the impulse response of the imaged tissue. For practical implementations, the EOP is more appealing since there is no need to perform deconvolution of the instrument response from the measured m-FLIM data, as in the case of EP. Our synthetic and experimental evaluations with m-FLIM datasets of human coronary atherosclerotic plaques show that low frequency indexes have to be employed for a distinctive representation of the EOP and EP, and to reduce noise distortion. The tissue classification of the m-FLIM datasets by EOP and EP also improves with low frequency indexes, and does not present significant differences by using either phasor. PMID:26114031

  3. The effect of exercise on prescription on physical activity and wellbeing in a multi-ethnic female population: A controlled trial.

    PubMed

    Gademan, Maaike G J; Deutekom, Marije; Hosper, Karen; Stronks, Karien

    2012-09-10

    In Western countries, individuals from multi-ethnic disadvantaged populations are less physically active than the Western population as a whole. This lack of physical activity (PA) may be one of the factors explaining disparities in health. Exercise on Prescription" (EoP), is an exercise program to which persons are referred by primary care. It has been developed to suit the needs of physically inactive women from diverse ethnic backgrounds living in deprived neighborhoods in the Netherlands. The effectiveness of this program has however, not yet been proven. A total of 514 women from diverse ethnic backgrounds were included in this study (192 EoP, 322 control group). Women in the EoP group participated in 18 sessions of supervised PA. The control group received care as usual. At baseline, 6 and 12 months the women attended an interview and a physical examination. Outcome measures were PA, BMI, weight circumference, fat percentage, oxygen uptake, mental well-being, subjective health and use of care. Of the participants 59% had a low educational level and 90% of the women were overweight or obese. Compliance was high, only 14% dropped out during the course of the program. Total PA did not change, PA during leisure time increased at 6 and at 12 months and PA during household activities increased at 12 months (PEoPvsControl < 0.05). EoP had no significant effect on the other outcome variables. EoP was successful in recruiting its target population and compliance was high. The effect of EoP on PA, health and mental well-being was limited. In this format EoP does not seem to be effective for increasing PA and the health status of non-Western migrant women. Dutch Trial register: NTR1294.

  4. A Two-Phase Space Resection Model for Accurate Topographic Reconstruction from Lunar Imagery with PushbroomScanners

    PubMed Central

    Xu, Xuemiao; Zhang, Huaidong; Han, Guoqiang; Kwan, Kin Chung; Pang, Wai-Man; Fang, Jiaming; Zhao, Gansen

    2016-01-01

    Exterior orientation parameters’ (EOP) estimation using space resection plays an important role in topographic reconstruction for push broom scanners. However, existing models of space resection are highly sensitive to errors in data. Unfortunately, for lunar imagery, the altitude data at the ground control points (GCPs) for space resection are error-prone. Thus, existing models fail to produce reliable EOPs. Motivated by a finding that for push broom scanners, angular rotations of EOPs can be estimated independent of the altitude data and only involving the geographic data at the GCPs, which are already provided, hence, we divide the modeling of space resection into two phases. Firstly, we estimate the angular rotations based on the reliable geographic data using our proposed mathematical model. Then, with the accurate angular rotations, the collinear equations for space resection are simplified into a linear problem, and the global optimal solution for the spatial position of EOPs can always be achieved. Moreover, a certainty term is integrated to penalize the unreliable altitude data for increasing the error tolerance. Experimental results evidence that our model can obtain more accurate EOPs and topographic maps not only for the simulated data, but also for the real data from Chang’E-1, compared to the existing space resection model. PMID:27077855

  5. A Two-Phase Space Resection Model for Accurate Topographic Reconstruction from Lunar Imagery with PushbroomScanners.

    PubMed

    Xu, Xuemiao; Zhang, Huaidong; Han, Guoqiang; Kwan, Kin Chung; Pang, Wai-Man; Fang, Jiaming; Zhao, Gansen

    2016-04-11

    Exterior orientation parameters' (EOP) estimation using space resection plays an important role in topographic reconstruction for push broom scanners. However, existing models of space resection are highly sensitive to errors in data. Unfortunately, for lunar imagery, the altitude data at the ground control points (GCPs) for space resection are error-prone. Thus, existing models fail to produce reliable EOPs. Motivated by a finding that for push broom scanners, angular rotations of EOPs can be estimated independent of the altitude data and only involving the geographic data at the GCPs, which are already provided, hence, we divide the modeling of space resection into two phases. Firstly, we estimate the angular rotations based on the reliable geographic data using our proposed mathematical model. Then, with the accurate angular rotations, the collinear equations for space resection are simplified into a linear problem, and the global optimal solution for the spatial position of EOPs can always be achieved. Moreover, a certainty term is integrated to penalize the unreliable altitude data for increasing the error tolerance. Experimental results evidence that our model can obtain more accurate EOPs and topographic maps not only for the simulated data, but also for the real data from Chang'E-1, compared to the existing space resection model.

  6. 76 FR 16277 - System Restoration Reliability Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... system restoration process. The Commission also approves the NERC's proposal to retire four existing EOP... prepare personnel to enable effective coordination of the system restoration process. The Commission also..., through the Reliability Standard development process, a modification to EOP-005-1 that identifies time...

  7. A comparative study of socio-demographic and substance use correlates in early onset psychosis

    PubMed Central

    Paruk, S; Jhazbhay, K; Singh, K; Sartorius, B; Burns, JK

    2016-01-01

    Background Comorbid substance use particularly cannabis among adolescents with mental illness is a major public health concern in developing countries with limited mental health resources. Better understanding of the association between cannabis use and other poly-substance use and early mental illness will provide for more targeted early interventions. Aim To examine the socio-demographic profile and cannabis use characteristics among adolescents with first episode early onset psychosis (EOP) and compare to age and gender matched adolescents with first episode non-psychotic mental illness (controls). Method Forty-five adolescents with first episode EOP and 45 controls were assessed using a clinical interview, PANSS and WHO ASSIST for substance related problems. Results There were significant socio-demographic differences among the adolescents with EOP (73% Black, 64% from low family income, 44% from rural areas) compared to controls (24% Black, 53% from low family income, 2% from rural areas). Whilst there was no difference in lifetime cannabis use, EOP adolescents differed in motivation for cannabis use, had increased current cannabis use (38%, p=0.01) and more frequent use (52%, p=0.04) compared to controls (16% current and 18% frequent use). EOP adolescents reported more hazardous use with higher ASSIST mean cannabis specific involvement scores (EOP 10,2; controls 2,3; p= 0.004). Conclusion The differences in socio-demographic variables may reflect the marked disparity in access to mental health care for rural Black youth. Psychotic youth may be more vulnerable to comorbid cannabis related problems than other mentally ill adolescents. The study highlights the need for early introduction of substance use interventions among adolescents with mental illness. PMID:27038079

  8. Associations between Prenatal and Early Childhood Fish and Processed Food Intake, Conduct Problems, and Co-Occurring Difficulties.

    PubMed

    Mesirow, Maurissa Sc; Cecil, Charlotte; Maughan, Barbara; Barker, Edward D

    2017-07-01

    Little is known about early life diet as a risk factor for early-onset persistent conduct problems (EOP CP). To investigate this, we used data from the Avon Longitudinal Study of Parents and Children, a UK-based prospective epidemiological birth cohort. 5727 mother-child pairs (49.9 % boys) monitored since pregnancy (delivery date between 1 April, 1991 and 31 December, 1992) reported intake of fish and processed foods at 32 weeks gestation and, for the child, at 3 years; EOP (n = 666) and Low conduct problem (Low CP, n = 5061) trajectories were measured from 4 to 13 years; hyperactivity and emotional difficulties were assessed in childhood (4-10 years) and early adolescence (12-13 years), in addition to potential confounding factors (family adversity, birth complications, income). Compared to Low CP, mothers of EOP children consumed less fish (p < 0.01) and more processed food (p < 0.05) prenatally, while EOP children consumed more processed food at 3 years (p < 0.05). For EOP, but not Low CP children, consuming less than two servings/week of fish (vs. two or more servings/week, p < 0.05), and one or more servings/day of processed food (vs. less than one serving/day, p < 0.01), was associated with higher emotional difficulties in early adolescence. Findings suggest that prenatal and postnatal diets high in processed food, and low in fish, associate with an EOP CP trajectory and co-occurring difficulties in early adolescence. As small effect size differences were found, further studies are needed to investigate the long-term impact of early unhealthy diet.

  9. Analysis of hepatocyte growth factor immunostaining in the placenta of HIV-infected normotensive versus preeclamptic pregnant women.

    PubMed

    Cele, S B; Odun-Ayo, F; Onyangunga, O A; Moodley, J; Naicker, T

    2018-08-01

    Hepatocyte Growth Factor (HGF) plays a role in the migration and morphogenesis of different cell types and tissues. Preeclampsia (PE) is associated with deficient trophoblast invasion and placental insufficiency; hence HGF production is expected to be compromised. This study therefore aimed to immunolocalize and morphometrically analyse placental HGF in normotensive versus PE pregnancies stratified by HIV status and gestational age. Normotensive (N; n = 40) and preeclamptic (PE; n = 80) women were stratified by HIV status (HIV- and HIV+), and gestational age i.e. early onset of PE (EOPE; <34 weeks) and late onset of PE (LOPE; ≥34 weeks). Placental tissues were stained using conventional immunohistochemistry, performed using mouse anti-human HGF antibody. Morphometric image analysis was performed using Zeiss Axio-Vision software. HGF was immuno-localized within the syncytiotrophoblast, cytotrophoblast, endothelial and fibroblast-like cell populations of both conducting and exchange villi. Based on pregnancy type, HGF immunoexpression within the conducting villi was significantly different between Nvs EOPE (p = 0.0372) and EOPE vs LOPE (p = 0.0006). Within the exchange villi, no significant difference of HGF immunostaining was noted between N vs EOPE and N vs LOPE. A down-regulation of HGF immuno-expression was observed in LOPE compared to other groups within both villi types, albeit non-significant. Based on HIV status, no significant difference in HGF immuno-expression was demonstrated between HIV- vs HIV + within the exchange and conducting villi. However, the expression of HGF in HIV- group was elevated in both villi types. Across the groups, a significant difference was found between N+ vs EOPE- (p  = 0.0207), EOPE+ vs LOPE- (p = 0.0036) and EOPE- vs LOPE- (p = 0.0016) of the conducting villi while no significant difference was found within the exchange villi. This novel study demonstrates that HGF was two-fold higher in conducting compared to exchange villi irrespective of the pregnancy type. HIV infection does not influence HGF expression within the conducting and exchange villi. The HGF/c-MET receptor complex may modulate the ligand expression within the placenta. Copyright © 2018 Elsevier B.V. All rights reserved.

  10. Far ultraviolet wide field imaging with a SPARTAN /Experiment of Opportunity/ Payload

    NASA Technical Reports Server (NTRS)

    Carruthers, G. R.; Heckathorn, H. M.; Opal, C. B.

    1982-01-01

    A wide-field electrographic Schmidt camera, sensitive in the far UV (1230-2000 A), has been developed and utilized in three sounding rocket flights. It is now being prepared for Shuttle flight as an Experiment of Opportunity Payload (EOP) (recently renamed as the SPARTAN program). In this paper, we discuss (1) design of the instrument and payload, particularly as influenced by our experience in rocket flights; (2) special problems of EOP in comparison to sounding rocket missions; (3) relationship of this experiment to, and special capabilities in comparison to, other space astronomy instruments such as Space Telescope; and (4) a tentative observing plan for an EOP mission.

  11. Integrating Analysis Goals for EOP, CRF and TRF

    NASA Technical Reports Server (NTRS)

    Ma, Chopo; MacMillan, D.; Petrov, L.; Smith, David E. (Technical Monitor)

    2001-01-01

    In a simplified, idealized way the TRF can be considered a set of positions at epoch and corresponding linear rates of change while the CRF is a set of fixed directions in space. VLBI analysis can be optimized for CRF and TRF separately while handling some of the complexity of geodetic and astrometric reality. For EOP time series both CRF and TRF should be accurate at the epoch of interest and well defined over time. The optimal integral EOP, TRF and CRF in a single VLBI solution configuration requires a detailed consideration of the data set and the possibly conflicting nature of reference frames.

  12. GGOS and the EOP - the key role of SLR for a stable estimation of highly accurate Earth orientation parameters

    NASA Astrophysics Data System (ADS)

    Bloßfeld, Mathis; Panzetta, Francesca; Müller, Horst; Gerstl, Michael

    2016-04-01

    The GGOS vision is to integrate geometric and gravimetric observation techniques to estimate consistent geodetic-geophysical parameters. In order to reach this goal, the common estimation of station coordinates, Stokes coefficients and Earth Orientation Parameters (EOP) is necessary. Satellite Laser Ranging (SLR) provides the ability to study correlations between the different parameter groups since the observed satellite orbit dynamics are sensitive to the above mentioned geodetic parameters. To decrease the correlations, SLR observations to multiple satellites have to be combined. In this paper, we compare the estimated EOP of (i) single satellite SLR solutions and (ii) multi-satellite SLR solutions. Therefore, we jointly estimate station coordinates, EOP, Stokes coefficients and orbit parameters using different satellite constellations. A special focus in this investigation is put on the de-correlation of different geodetic parameter groups due to the combination of SLR observations. Besides SLR observations to spherical satellites (commonly used), we discuss the impact of SLR observations to non-spherical satellites such as, e.g., the JASON-2 satellite. The goal of this study is to discuss the existing parameter interactions and to present a strategy how to obtain reliable estimates of station coordinates, EOP, orbit parameter and Stokes coefficients in one common adjustment. Thereby, the benefits of a multi-satellite SLR solution are evaluated.

  13. Approach for Improving the Integrated Sensor Orientation

    NASA Astrophysics Data System (ADS)

    Mitishita, E.; Ercolin Filho, L.; Graça, N.; Centeno, J.

    2016-06-01

    The direct determination of exterior orientation parameters (EOP) of aerial images via integration of the Inertial Measurement Unit (IMU) and GPS is often used in photogrammetric mapping nowadays. The accuracies of the EOP depend on the accurate parameters related to sensors mounting when the job is performed (offsets of the IMU relative to the projection centre and the angles of boresigth misalignment between the IMU and the photogrammetric coordinate system). In principle, when the EOP values do not achieve the required accuracies for the photogrammetric application, the approach, known as Integrated Sensor Orientation (ISO), is used to refine the direct EOP. ISO approach requires accurate Interior Orientation Parameters (IOP) and standard deviation of the EOP under flight condition. This paper investigates the feasibility of use the in situ camera calibration to obtain these requirements. The camera calibration uses a small sub block of images, extracted from the entire block. A digital Vexcel UltraCam XP camera connected to APPLANIX POS AVTM system was used to get two small blocks of images that were use in this study. The blocks have different flight heights and opposite flight directions. The proposed methodology improved significantly the vertical and horizontal accuracies of the 3D point intersection. Using a minimum set of control points, the horizontal and vertical accuracies achieved nearly one image pixel of resolution on the ground (GSD). The experimental results are shown and discussed.

  14. Student Learning in Student Services Extended Opportunity Program & Services

    ERIC Educational Resources Information Center

    Soltani, Parisa

    2013-01-01

    The purpose of this mixed methods study was to investigate the relationship between student learning and participation in Equal Opportunity Programs and Services (EOP&S) at Irvine Valley College (IVC). An embedded survey design was developed using William Sedlacek's non-cognitive questionnaire (NCQ), items from the Community College Survey of…

  15. EOP and SAA Undergraduates Who Left UC Davis without a Degree.

    ERIC Educational Resources Information Center

    Rasor, Marianne

    Undergraduate students enrolled in the Educational Opportunity Program (EOP) or the Student Affirmative Action (SAA) program at the University of California (UC), Davis, who withdrew before graduation were surveyed in 1981. Attention was directed to the respondents' educational experiences after leaving, their current employment, and their…

  16. New families of superintegrable systems from Hermite and Laguerre exceptional orthogonal polynomials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marquette, Ian; Quesne, Christiane

    2013-04-15

    In recent years, many exceptional orthogonal polynomials (EOP) were introduced and used to construct new families of 1D exactly solvable quantum potentials, some of which are shape invariant. In this paper, we construct from Hermite and Laguerre EOP and their related quantum systems new 2D superintegrable Hamiltonians with higher-order integrals of motion and the polynomial algebras generated by their integrals of motion. We obtain the finite-dimensional unitary representations of the polynomial algebras and the corresponding energy spectrum. We also point out a new type of degeneracies of the energy levels of these systems that is associated with holes in sequencesmore » of EOP.« less

  17. Noncognitive Variables and Student Learning in Extended Opportunity Programs and Services (EOPS)

    ERIC Educational Resources Information Center

    Soltani, Parisa; Gutierrez Keeton, Rebecca; Hoffman, John L.

    2017-01-01

    The purpose of this mixed methods study was to investigate the relationship between participation in Extended Opportunity Programs and Services (EOPS) at California Valley College (CVC) (one of the 113 California Community Colleges in California) and several measures of student learning. An embedded survey design was developed using William…

  18. Black, Asian, and White Students in the Educational Opportunity Program.

    ERIC Educational Resources Information Center

    Maykovich, Minako K.

    The Educational Opportunity Program (EOP) was established for the sake of students who might not qualify for higher education through regular channels because of their previous financial and scholastic disadvantages. The issue is whether or not EOP is successful in recruiting and developing disadvantaged but high potential students. This report…

  19. Facial emotion identification in early-onset psychosis.

    PubMed

    Barkl, Sophie J; Lah, Suncica; Starling, Jean; Hainsworth, Cassandra; Harris, Anthony W F; Williams, Leanne M

    2014-12-01

    Facial emotion identification (FEI) deficits are common in patients with chronic schizophrenia and are strongly related to impaired functioning. The objectives of this study were to determine whether FEI deficits are present and emotion specific in people experiencing early-onset psychosis (EOP), and related to current clinical symptoms and functioning. Patients with EOP (n=34, mean age=14.11, 53% female) and healthy controls (HC, n=42, mean age 13.80, 51% female) completed a task of FEI that measured accuracy, error pattern and response time. Relative to HC, patients with EOP (i) had lower accuracy for identifying facial expressions of emotions, especially fear, anger and disgust, (ii) were more likely to misattribute other emotional expressions as fear or disgust, and (iii) were slower at accurately identifying all facial expressions. FEI accuracy was not related to clinical symptoms or current functioning. Deficits in FEI (especially for fear, anger and disgust) are evident in EOP. Our findings suggest that while emotion identification deficits may reflect a trait susceptibility marker, functional deficits may represent a sequelae of illness. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Quantification of Maternal Serum Cell-Free Fetal DNA in Early-Onset Preeclampsia

    PubMed Central

    Yu, Hong; Shen, Yanting; Ge, Qinyu; He, Youji; Qiao, Dongyan; Ren, Mulan; Zhang, Jianqiong

    2013-01-01

    The aim of this study was to determine whether the increased serum cell-free fetal DNA (cffDNA) level of gravidas developed into early-onset preeclampsia (EOPE) subsequently in the early second trimesters is related to prenatal screening markers. Serum was collected from 1011 gravidas. The level of cffDNA and prenatal screening markers were analyzed in 20 cases with EOPE and 20 controls. All fetuses were male. The maternal serum cffDNA level was assessed by amplification of the Y chromosome specific gene. Correlations between the variables were examined. (Logged) cffDNA in EOPE (median, 3.08; interquartile range, 2.93–3.68) was higher than controls (median, 1.79; interquartile range, 1.46–2.53). The increased level of (logged) cffDNA was correlated significantly with the increased human chorionic gonadotropin (HCG) level (r = 0.628, p < 0.001). Significant reciprocal correlations between cffDNA and babies’ birth weight as well as gestation weeks at delivery were noted (r = −0.516, p = 0.001; r = −0.623, p < 0.001, respectively). The sensitivity and specificity of cffDNA to discriminate between the EOPE cases and the controls were 90% and 85%, respectively. CffDNA is a potential marker for EOPE, which had a significant reciprocal correlation with babies’ birth weight and gestation weeks at delivery. Moreover, it may help in indicating the underlying hypoxic condition in the placenta. PMID:23567271

  1. Screening hundreds of emerging organic pollutants (EOPs) in surface water from the Yangtze River Delta (YRD): Occurrence, distribution, ecological risk.

    PubMed

    Peng, Ying; Fang, Wendi; Krauss, Martin; Brack, Werner; Wang, Zhihao; Li, Feilong; Zhang, Xiaowei

    2018-06-04

    Increased synthetic chemical production and diversification in developing countries caused serious aquatic pollution worldwide with emerging organic pollutants (EOPs) detected in surface water rising health concerns to human and aquatic ecosystem even at low ng/L concentration with long-term exposure. The Yangtze River Delta (YRD) area serves agriculture and industry for people in eastern China. However, the current knowledge on the occurrence and ecological risk of diverse EOPs which are present in the aquatic environment is limited. This study was to investigate the complexity and diversity of EOPs in surface water from 28 sampling sites, which were selected to represent urban, industrial or agriculture areas in the YRD area. In total 484 chemicals were analyze by a target screening approach using liquid chromatography coupled to high-resolution tandem mass spectrometry (LC-HRMS/MS). 181 out of 484 EOPs were detected at least one site in the YRD area, and 44 analytes, mostly industrial chemicals and pesticides, were ubiquitous at all sampling sites. Most EOPs were industrial chemicals with 1H-benzotriazole and organophosphate flame retardants (PFRs) as the chemicals with highest concentrations. For 21 pesticides, mostly herbicides, maximum concentrations of atrazine and isoproturon were above the annual average environmental quality standards of Europe. Amantadine and DEET were the dominant pharmceuticals and personal care products (PPCPs) in the YRD area. Compared to urban areas (mostly in Qinhuai River), chemical profiles from industrial areas were more complex. Industrial activities likely have a strong impact on the composition of chemical mixtures in surface water from the YRD area. ISO E Super, 4-methylbenzylidene camphor and clotrimazole detected in this study are potentially persistent and bioaccumulative chemicals. Furthermore, results of risk assessment showed that hazard quotients of dimethyldioctadecylammonium, didecyldimethylammonium and octocrylene were higher than one and occur frequently, which indicates possibly adverse effects on fish species in the YRD area. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. Towards an Integrated Approach to Cabin Service English Curriculum Design: A Case Study of China Southern Airlines' Cabin Service English Training Course

    ERIC Educational Resources Information Center

    Xiaoqin, Liu; Wenzhong, Zhu

    2016-01-01

    This paper has reviewed the history of EOP (training) development and then illustrated the curriculum design of cabin service English training from the three perspectives of ESP, CLIL and Business Discourse. It takes the cabin crew English training of China Southern Airlines (CZ) as the case and puts forward an operational framework composed of…

  3. 78 FR 24285 - Self-Regulatory Organizations; C2 Options Exchange, Incorporated; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... opening size (``EOS'') information that is disseminated prior to the opening of the market and during trading rotations (collectively, ``EOP/EOS data'').\\6\\ \\6\\ The Exchange identified the inclusion of EOP/EOS data in the C2 BBO Data Feed in a proposed rule change filed in January 2013. See Securities...

  4. Students' Experiences with Supports Offered in Educational Opportunity Programs That Lead to Their Persistence in Postsecondary Education

    ERIC Educational Resources Information Center

    Beauchemin, Amy J.

    2017-01-01

    The purpose of this single case study was to gain a deeper understanding of the supports provided by postsecondary education institutions to students in Educational Opportunity Programs (EOPs). EOPs provide typically low-income, first generation, academically underprepared, and underserved students, who are often overlooked but show potential,…

  5. Integrating Analysis Goals for EOP, CRF and TRF

    NASA Technical Reports Server (NTRS)

    Ma, Chopo; MacMillan, Daniel; Petrov, Leonid

    2002-01-01

    In a simplified, idealized way the TRF (Terrestrial Reference Frame) can be considered a set of positions at epoch and corresponding linear rates of change while the CRF (Celestial Reference Frame) is a set of fixed directions in space. VLBI analysis can be optimized for CRF and TRF separately while handling some of the complexity of geodetic and astrometric reality. For EOP (Earth Orientation Parameter) time series both CRF and TRF should be accurate at the epoch of interest and well defined over time. The optimal integration of EOP, TRF and CRF in a single VLBI solution configuration requires a detailed consideration of the data set and the possibly conflicting nature of the reference frames. A possible approach for an integrated analysis is described.

  6. Entanglement of purification in free scalar field theories

    NASA Astrophysics Data System (ADS)

    Bhattacharyya, Arpan; Takayanagi, Tadashi; Umemoto, Koji

    2018-04-01

    We compute the entanglement of purification (EoP) in a 2d free scalar field theory with various masses. This quantity measures correlations between two subsystems and is reduced to the entanglement entropy when the total system is pure. We obtain explicit numerical values by assuming minimal gaussian wave functionals for the purified states. We find that when the distance between the subsystems is large, the EoP behaves like the mutual information. However, when the distance is small, the EoP shows a characteristic behavior which qualitatively agrees with the conjectured holographic computation and which is different from that of the mutual information. We also study behaviors of mutual information in purified spaces and violations of monogamy/strong superadditivity.

  7. Basic symptoms in the general population and in psychotic and non-psychotic psychiatric adolescents.

    PubMed

    Meng, Heiner; Schimmelmann, Benno Graf; Koch, Eginhard; Bailey, Barbara; Parzer, Peter; Günter, Michael; Mohler, Beat; Kunz, Natalia; Schulte-Markwort, Michael; Felder, Wilhelm; Zollinger, Rudolf; Bürgin, Dieter; Resch, Franz

    2009-06-01

    Cognitive-perceptive 'basic symptoms' are used complementary to ultra-high-risk criteria in order to predict onset of psychosis in the pre-psychotic phase. The aim was to investigate the prevalence of a broad selection of 'basic symptoms' in a representative general adolescent population sample (GPS; N=96) and to compare it with adolescents first admitted for early onset psychosis (EOP; N=87) or non-psychotic psychiatric disorders (NP; N=137). Subjects were assessed with the Bonn Scale for the Assessment of Basic Symptoms (BSABS). Prevalence of at least one 'basic symptom' and mean numbers were compared across the three groups. Logistic regression was used to predict group membership by BSABS subscales; risk ratios were calculated to identify 'basic symptoms' which best discriminated between groups. The prevalence of at least any one 'basic symptom' was 30.2% in GPS compared to 81% in NP and 96.5% in EOP. Correct classification of EOP when compared to GPS was high (94.0%) and lower when compared to NP (78.6%). Cognitive symptoms discriminated best between EOP and NP. Alike other prodromal- and psychotic-like experiences, 'basic symptoms' are prevalent in the general adolescent population, yet at a lower rate compared to EOP and NP. The usage of 'at least one basic symptom' as a screening criterion for youth at risk of developing a psychotic disorder is not recommended in the general population or in unselected psychiatrically ill adolescents. However, particularly cognitive 'basic symptoms' may be a valuable criteria to be included in future 'at risk' studies in adolescents.

  8. Rigorous Combination of GNSS and VLBI: How it Improves Earth Orientation and Reference Frames

    NASA Astrophysics Data System (ADS)

    Lambert, S. B.; Richard, J. Y.; Bizouard, C.; Becker, O.

    2017-12-01

    Current reference series (C04) of the International Earth Rotation and Reference Systems Service (IERS) are produced by a weighted combination of Earth orientation parameters (EOP) time series built up by combination centers of each technique (VLBI, GNSS, Laser ranging, DORIS). In the future, we plan to derive EOP from a rigorous combination of the normal equation systems of the four techniques.We present here the results of a rigorous combination of VLBI and GNSS pre-reduced, constraint-free, normal equations with the DYNAMO geodetic analysis software package developed and maintained by the French GRGS (Groupe de Recherche en GeÌodeÌsie Spatiale). The used normal equations are those produced separately by the IVS and IGS combination centers to which we apply our own minimal constraints.We address the usefulness of such a method with respect to the classical, a posteriori, combination method, and we show whether EOP determinations are improved.Especially, we implement external validations of the EOP series based on comparison with geophysical excitation and examination of the covariance matrices. Finally, we address the potential of the technique for the next generation celestial reference frames, which are currently determined by VLBI only.

  9. Ultrafast electron-optical phonon scattering and quasiparticle lifetime in CVD-grown graphene.

    PubMed

    Shang, Jingzhi; Yu, Ting; Lin, Jianyi; Gurzadyan, Gagik G

    2011-04-26

    Ultrafast quasiparticle dynamics in graphene grown by chemical vapor deposition (CVD) has been studied by UV pump/white-light probe spectroscopy. Transient differential transmission spectra of monolayer graphene are observed in the visible probe range (400-650 nm). Kinetics of the quasiparticle (i.e., low-energy single-particle excitation with renormalized energy due to electron-electron Coulomb, electron-optical phonon (e-op), and optical phonon-acoustic phonon (op-ap) interactions) was monitored with 50 fs resolution. Extending the probe range to near-infrared, we find the evolution of quasiparticle relaxation channels from monoexponential e-op scattering to double exponential decay due to e-op and op-ap scattering. Moreover, quasiparticle lifetimes of mono- and randomly stacked graphene films are obtained for the probe photon energies continuously from 1.9 to 2.3 eV. Dependence of quasiparticle decay rate on the probe energy is linear for 10-layer stacked graphene films. This is due to the dominant e-op intervalley scattering and the linear density of states in the probed electronic band. A dimensionless coupling constant W is derived, which characterizes the scattering strength of quasiparticles by lattice points in graphene.

  10. Anharmonic vibrational analysis of s-trans and s-cis conformers of acryloyl fluoride using numerical-analytic Van Vleck operator perturbation theory

    NASA Astrophysics Data System (ADS)

    Krasnoshchekov, Sergey V.; Craig, Norman C.; Koroleva, Lidiya A.; Stepanov, Nikolay F.

    2018-01-01

    A new gas-phase infrared (IR) spectrum of acryloyl fluoride (ACRF, CH2dbnd CHsbnd CFdbnd O) with a resolution of 0.1 cm- 1 in the range 4000-450 cm- 1 was measured. Theoretical ab initio molecular structures, full quartic potential energy surfaces (PES), and cubic surfaces of dipole moments and polarizability tensor components (electro-optical properties, EOP) of the s-trans and s-cis conformers of the ACRF were calculated by the second-order Møller-Plesset electronic perturbation theory with a correlation consistent Dunning triple-ζ basis set. The numerical-analytic implementation of the second-order operator canonical Van Vleck perturbation theory was employed for predicting anharmonic IR and Raman scattering (RS) spectra of ACRF. To improve the anharmonic predictions, harmonic frequencies were replaced by their counterparts evaluated with the higher-level CCSD(T)/cc-pVTZ model, to form a ;hybrid; PES. The original operator representation of the Hamiltonian is analytically reduced to a quasi-diagonal form, integrated in the harmonic oscillator basis and diagonalized to account for strong resonance couplings. Double canonical transformations of EOP expansions enabled prediction of integral intensities of both fundamental and multi-quanta transitions in IR/RS spectra. Enhanced band shape analysis reinforced the assignments. A thorough interpretation of the new IR experimental spectra and existing matrix-isolation literature data for the mixture of two conformers of ACRF was accomplished, and a number of assignments clarified.

  11. Does Diagnostic Classification of Early-Onset Psychosis Change over Follow-Up?

    ERIC Educational Resources Information Center

    Fraguas, David; de Castro, Maria J.; Medina, Oscar; Parellada, Mara; Moreno, Dolores; Graell, Montserrat; Merchan-Naranjo, Jessica; Arango, Celso

    2008-01-01

    Objective: To examine the diagnostic stability and the functional outcome of patients with early-onset psychosis (EOP) over a 2-year follow-up period. Methods: A total of 24 patients (18 males (75%) and 6 females (25%), mean age [plus or minus] SD: 15.7 [plus or minus] 1.6 years) with a first episode of EOP formed the sample. Psychotic symptoms…

  12. Testing impact of the strategy of VLBI data analysis on the estimation of Earth Orientation Parameters and station coordinates

    NASA Astrophysics Data System (ADS)

    Wielgosz, Agata; Tercjak, Monika; Brzeziński, Aleksander

    2016-06-01

    Very Long Baseline Interferometry (VLBI) is the only space geodetic technique capable to realise the Celestial Reference Frame and tie it with the Terrestrial Reference Frame. It is also the only technique, which measures all the Earth Orientation Parameters (EOP) on a regular basis, thus the role of VLBI in determination of the universal time, nutation and polar motion and station coordinates is invaluable. Although geodetic VLBI has been providing observations for more than 30 years, there are no clear guidelines how to deal with the stations or baselines having significantly bigger post-fit residuals than the other ones. In our work we compare the common weighting strategy, using squared formal errors, with strategies involving exclusion or down-weighting of stations or baselines. For that purpose we apply the Vienna VLBI Software VieVS with necessary additional procedures. In our analysis we focus on statistical indicators that might be the criterion of excluding or down-weighting the inferior stations or baselines, as well as on the influence of adopted strategy on the EOP and station coordinates estimation. Our analysis shows that in about 99% of 24-hour VLBI sessions there is no need to exclude any data as the down-weighting procedure is sufficiently efficient. Although results presented here do not clearly indicate the best algorithm, they show strengths and weaknesses of the applied methods and point some limitations of automatic analysis of VLBI data. Moreover, it is also shown that the influence of the adopted weighting strategy is not always clearly reflected in the results of analysis.

  13. Genome-wide hypermethylation coupled with promoter hypomethylation in the chorioamniotic membranes of early onset pre-eclampsia

    PubMed Central

    Ching, Travers; Song, Min-Ae; Tiirikainen, Maarit; Molnar, Janos; Berry, Marla; Towner, Dena; Garmire, Lana X.

    2014-01-01

    Pre-eclampsia is the leading cause of fetal and maternal morbidity and mortality. Early onset pre-eclampsia (EOPE) is a disorder that has severe maternal and fetal outcomes, whilst its etiology is poorly understood. We hypothesize that epigenetics plays an important role to mediate the development of EOPE and conducted a case–control study to compare the genome-wide methylome difference between chorioamniotic membranes from 30 EOPE and 17 full-term pregnancies using the Infinium Human Methylation 450 BeadChip arrays. Bioinformatics analysis tested differential methylation (DM) at CpG site level, gene level, and pathway and network level. A striking genome-wide hypermethylation pattern coupled with hypomethylation in promoters was observed. Out of 385 184 CpG sites, 9995 showed DM (2.6%). Of those DM sites, 91.9% showed hypermethylation (9186 of 9995). Over 900 genes had DM associated with promoters. Promoter-based DM analysis revealed that genes in canonical cancer-related pathways such as Rac, Ras, PI3K/Akt, NFκB and ErBB4 were enriched, and represented biological functional alterations that involve cell cycle, apoptosis, cancer signaling and inflammation. A group of genes previously found to be up-regulated in pre-eclampsia, including GRB2, ATF3, NFKB2, as well as genes in proteasome subunits (PSMA1, PMSE1, PSMD1 and PMSD8), harbored hypomethylated promoters. Contrarily, a cluster of microRNAs, including mir-519a1, mir-301a, mir-487a, mir-185, mir-329, mir-194, mir-376a1, mir-486 and mir-744 were all hypermethylated in their promoters in the EOPE samples. These findings collectively reveal new avenues of research regarding the vast epigenetic modifications in EOPE. PMID:24944161

  14. Impact of the long chain omega-acylceramides on the stratum corneum lipid nanostructure. Part 1: Thermotropic phase behaviour of CER[EOS] and CER[EOP] studied using X-ray powder diffraction and FT-Raman spectroscopy.

    PubMed

    Kessner, Doreen; Brezesinski, Gerald; Funari, Sergio S; Dobner, Bodo; Neubert, Reinhard H H

    2010-01-01

    The stratum corneum (SC), the outermost layer of the mammalian skin, is the main skin barrier. Ceramides (CERs) as the major constituent of the SC lipid matrix are of particular interest. At the moment, 11 classes of CERs are identified, but the effect of each single ceramide species is still not known. Therefore in this article, the thermotropic behaviour of the long chain omega-acylceramides CER[EOS] and CER[EOP] was studied using X-ray powder diffraction and FT-Raman spectroscopy. It was found that the omega-acylceramides CER[EOS] and CER[EOP] do not show a pronounced polymorphism which is observed for shorter chain ceramides as a significant feature. The phase behaviour of both ceramides is strongly influenced by the extremely long acyl-chain residue. The latter has a much stronger influence compared with the structure of the polar head group, which is discussed as extremely important for the appearance of a rich polymorphism. Despite the strong influence of the long chain, the additional OH-group of the phyto-sphingosine type CER[EOP] influences the lamellar repeat distance and the chain packing. The less polar sphingosine type CER[EOS] is stronger influenced by the long acyl-chain residue. Hydration is necessary for the formation of an extended hydrogen-bonding network between the polar head groups leading to the appearance of a long-periodicity phase (LPP). In contrast, the more polar CER[EOP] forms the LPP with densely packed alkyl chains already in the dry state.

  15. Assessment of state- and territorial-level preparedness capacity for serving deaf and hard-of-hearing populations in disasters.

    PubMed

    Ivey, Susan L; Tseng, Winston; Dahrouge, Donna; Engelman, Alina; Neuhauser, Linda; Huang, Debbie; Gurung, Sidhanta

    2014-01-01

    Substantial evidence exists that emergency preparedness and response efforts are not effectively reaching populations with functional and access needs, especially barriers related to literacy, language, culture, or disabilities. More than 36 million Americans are Deaf or hard of hearing (Deaf/HH). These groups experienced higher risks of injury, death, and property loss in recent disasters than the general public. We conducted a participatory research study to examine national recommendations on preparedness communication for the Deaf/HH. We assessed whether previous recommendations regarding the Deaf/HH have been incorporated into state- and territorial-level emergency operations plans (EOPs), interviewed state- and territorial-level preparedness directors about capacity to serve the Deaf/HH, and proposed strategies to benefit Deaf/HH populations during emergencies. We analyzed 55 EOPs and 50 key informant (KI) interviews with state directors. Fifty-five percent of EOPs mentioned vulnerable populations; however, only 31% specifically mentioned Deaf/HH populations in their plan. Study findings indicated significant relationships among the following factors: a state-level KI's familiarity with communication issues for the Deaf/HH, making relay calls (i.e., calls to services to relay communication between Deaf and hearing people), and whether the KI's department provides trainings about serving Deaf/HH populations in emergencies. We found significant associations between a state's percentage of Deaf/HH individuals and a KI's familiarity with Deaf/HH communication issues and provision by government of any disability services to Deaf/HH populations in emergencies. Further, we found significant relationships between KIs attending training on serving the Deaf/HH and familiarity with Deaf/HH communication issues, including how to make relay calls. This study provides new knowledge that can help emergency agencies improve their preparedness training, planning, and capacity to serve Deaf/HH populations in emergencies.

  16. Incorporating high-pressure electroosmotic pump and a nano-flow gradient generator into a miniaturized liquid chromatographic system for peptide analysis.

    PubMed

    Chen, Apeng; Lynch, Kyle B; Wang, Xiaochun; Lu, Joann J; Gu, Congying; Liu, Shaorong

    2014-09-24

    We integrate a high-pressure electroosmotic pump (EOP), a nanoflow gradient generator, and a capillary column into a miniaturized liquid chromatographic system that can be directly coupled with a mass spectrometer for proteomic analysis. We have recently developed a low-cost high-pressure EOP capable of generating pressure of tens of thousands psi, ideal for uses in miniaturized HPLC. The pump worked smoothly when it was used for isocratic elutions. When it was used for gradient elutions, generating reproducible gradient profiles was challenging; because the pump rate fluctuated when the pump was used to pump high-content organic solvents. This presents an issue for separating proteins/peptides since high-content organic solvents are often utilized. In this work, we solve this problem by incorporating our high-pressure EOP with a nano-flow gradient generator so that the EOP needs only to pump an aqueous solution. With this combination, we develop a capillary-based nano-HPLC system capable of performing nano-flow gradient elution; the pump rate is stable, and the gradient profiles are reproducible and can be conveniently tuned. To demonstrate its utility, we couple it with either a UV absorbance detector or a mass spectrometer for peptide separations. Copyright © 2014. Published by Elsevier B.V.

  17. Bupropion in the treatment of problematic online game play in patients with major depressive disorder.

    PubMed

    Han, Doug Hyun; Renshaw, Perry F

    2012-05-01

    As one of the problematic behaviors in patients with major depressive disorder (MDD), excessive online game play (EOP) has been reported in a number of recent studies. Bupropion has been evaluated as a potential treatment for MDD and substance dependence. We hypothesized that bupropion treatment would reduce the severity of EOP as well as depressive symptoms. Fifty male subjects with comorbid EOP and MDD were randomly assigned to bupropion + education for internet use (EDU) or placebo + EDU groups. The current study consisted in a 12-week, prospective, randomized, double-blind clinical trial, including an eight-week active treatment phase and a four-week post treatment follow-up period. During the active treatment period, Young Internet Addiction Scale (YIAS) scores and the mean time of online game playing in the bupropion group were greatly reduced compared with those of the placebo group. The Beck Depression Inventory (BDI) scores in the bupropion group were also greatly reduced compared with those of the placebo group. During the four-week post-treatment follow-up period, bupropion-associated reductions in online game play persisted, while depressive symptoms recurred. Conclusively, bupropion may improve depressive mood as well as reduce the severity of EOP in patients with comorbid MDD and online game addiction.

  18. Bupropion in the treatment of problematic online game play in patients with major depressive disorder

    PubMed Central

    Han, Doug Hyun; Renshaw, Perry F

    2015-01-01

    As one of the problematic behaviors in patients with major depressive disorder (MDD), excessive online game play (EOP) has been reported in a number of recent studies. Bupropion has been evaluated as a potential treatment for MDD and substance dependence. We hypothesized that bupropion treatment would reduce the severity of EOP as well as depressive symptoms. Fifty male subjects with comorbid EOP and MDD were randomly assigned to bupropion + education for internet use (EDU) or placebo + EDU groups. The current study consisted in a 12-week, prospective, randomized, double-blind clinical trial, including an eight-week active treatment phase and a four-week post treatment follow-up period. During the active treatment period, Young Internet Addiction Scale (YIAS) scores and the mean time of online game playing in the bupropion group were greatly reduced compared with those of the placebo group. The Beck Depression Inventory (BDI) scores in the bupropion group were also greatly reduced compared with those of the placebo group. During the four-week post-treatment follow-up period, bupropion-associated reductions in online game play persisted, while depressive symptoms recurred. Conclusively, bupropion may improve depressive mood as well as reduce the severity of EOP in patients with comorbid MDD and online game addiction. PMID:21447539

  19. FSW between Al alloy and Mg Alloy: the comparative study

    NASA Astrophysics Data System (ADS)

    Jagadeesha, C. B.

    2017-04-01

    It is difficult to fusion weld Al alloy to Mg alloy, so by experimental optimization procedure (EOP) optimum parameters for FSW between Al alloy and Mg alloy were determined and experiment conducted using these parameters resulted in not only sound weld but also highest strength weld for 5 mm thickness of the alloys plates. One can arrive to optimum parameters by following the EOP in case of similar and dissimilar materials FSW, such as Al alloy and Mg alloy FSW. It has observed that tensile sample having least thickness intermetallics (IMs) layer has highest strength compared to sample with larger thickness of intermetallics layer and also it has observed that weld of lesser thickness plates have strength higher than welds of larger thickness plates. It has observed that, Vickers hardness in WN i.e. on the region containing layers of IMs is considerably higher, which leads to emerge of new type of laminated composite materials. It has observed that, it is the least thickness IMs layers in the weld are responsible for higher strength of weld not the ductility of the IMs formed owing to the insertion of intermediate material in the weld. It has found that coefficient of friction is =0.25, in case of bead on plate welding of Mg alloy.

  20. Geometric Calibration of Full Spherical Panoramic Ricoh-Theta Camera

    NASA Astrophysics Data System (ADS)

    Aghayari, S.; Saadatseresht, M.; Omidalizarandi, M.; Neumann, I.

    2017-05-01

    A novel calibration process of RICOH-THETA, full-view fisheye camera, is proposed which has numerous applications as a low cost sensor in different disciplines such as photogrammetry, robotic and machine vision and so on. Ricoh Company developed this camera in 2014 that consists of two lenses and is able to capture the whole surrounding environment in one shot. In this research, each lens is calibrated separately and interior/relative orientation parameters (IOPs and ROPs) of the camera are determined on the basis of designed calibration network on the central and side images captured by the aforementioned lenses. Accordingly, designed calibration network is considered as a free distortion grid and applied to the measured control points in the image space as correction terms by means of bilinear interpolation. By performing corresponding corrections, image coordinates are transformed to the unit sphere as an intermediate space between object space and image space in the form of spherical coordinates. Afterwards, IOPs and EOPs of each lens are determined separately through statistical bundle adjustment procedure based on collinearity condition equations. Subsequently, ROPs of two lenses is computed from both EOPs. Our experiments show that by applying 3*3 free distortion grid, image measurements residuals diminish from 1.5 to 0.25 degrees on aforementioned unit sphere.

  1. High-performance, low-voltage electroosmotic pumps with molecularly thin silicon nanomembranes

    PubMed Central

    Snyder, Jessica L.; Getpreecharsawas, Jirachai; Fang, David Z.; Gaborski, Thomas R.; Striemer, Christopher C.; Fauchet, Philippe M.; Borkholder, David A.; McGrath, James L.

    2013-01-01

    We have developed electroosmotic pumps (EOPs) fabricated from 15-nm-thick porous nanocrystalline silicon (pnc-Si) membranes. Ultrathin pnc-Si membranes enable high electroosmotic flow per unit voltage. We demonstrate that electroosmosis theory compares well with the observed pnc-Si flow rates. We attribute the high flow rates to high electrical fields present across the 15-nm span of the membrane. Surface modifications, such as plasma oxidation or silanization, can influence the electroosmotic flow rates through pnc-Si membranes by alteration of the zeta potential of the material. A prototype EOP that uses pnc-Si membranes and Ag/AgCl electrodes was shown to pump microliter per minute-range flow through a 0.5-mm-diameter capillary tubing with as low as 250 mV of applied voltage. This silicon-based platform enables straightforward integration of low-voltage, on-chip EOPs into portable microfluidic devices with low back pressures. PMID:24167263

  2. Impact of orbit, clock and EOP errors in GNSS Precise Point Positioning

    NASA Astrophysics Data System (ADS)

    Hackman, C.

    2012-12-01

    Precise point positioning (PPP; [1]) has gained ever-increasing usage in GNSS carrier-phase positioning, navigation and timing (PNT) since its inception in the late 1990s. In this technique, high-precision satellite clocks, satellite ephemerides and earth-orientation parameters (EOPs) are applied as fixed input by the user in order to estimate receiver/location-specific quantities such as antenna coordinates, troposphere delay and receiver-clock corrections. This is in contrast to "network" solutions, in which (typically) less-precise satellite clocks, satellite ephemerides and EOPs are used as input, and in which these parameters are estimated simultaneously with the receiver/location-specific parameters. The primary reason for increased PPP application is that it offers most of the benefits of a network solution with a smaller computing cost. In addition, the software required to do PPP positioning can be simpler than that required for network solutions. Finally, PPP permits high-precision positioning of single or sparsely spaced receivers that may have few or no GNSS satellites in common view. A drawback of PPP is that the accuracy of the results depend directly on the accuracy of the supplied orbits, clocks and EOPs, since these parameters are not adjusted during the processing. In this study, we will examine the impact of orbit, EOP and satellite clock estimates on PPP solutions. Our primary focus will be the impact of these errors on station coordinates; however the study may be extended to error propagation into receiver-clock corrections and/or troposphere estimates if time permits. Study motivation: the United States Naval Observatory (USNO) began testing PPP processing using its own predicted orbits, clocks and EOPs in Summer 2012 [2]. The results of such processing could be useful for real- or near-real-time applications should they meet accuracy/precision requirements. Understanding how errors in satellite clocks, satellite orbits and EOPs propagate into PPP positioning and timing results allows researchers to focus their improvement efforts in areas most in need of attention. The initial study will be conducted using the simulation capabilities of Bernese GPS Software and extended to using real data if time permits. [1] J.F. Zumberge, M.B. Heflin, D.C. Jefferson, M.M. Watkins and F.H. Webb, Precise point positioning for the efficient and robust analysis of GPS data from large networks, J. Geophys. Res., 102(B3), 5005-5017, doi:10.1029/96JB03860, 1997. [2] C. Hackman, S.M. Byram, V.J. Slabinski and J.C. Tracey, Near-real-time and other high-precision GNSS-based orbit/clock/earth-orientation/troposphere parameters available from USNO, Proc. 2012 ION Joint Navigation Conference, 15 pp., in press, 2012.

  3. Co-occurring problems of early onset persistent, childhood limited, and adolescent onset conduct problem youth.

    PubMed

    Barker, Edward D; Oliver, Bonamy R; Maughan, Barbara

    2010-11-01

    It is increasingly recognized that youth who follow early onset persistent (EOP), childhood limited (CL) and adolescent onset (AO) trajectories of conduct problems show somewhat varying patterns of risk (in childhood) and adjustment problems (in adolescence and adulthood). Little, however, is known about how other adjustment problems differentially co-develop with the EOP, CL and AO trajectories across the childhood and adolescent years. Using data from the Avon Longitudinal Study of Parents and Children, an epidemiological, longitudinal cohort of boys and girls, we estimated growth curves for parent-reported hyperactivity, emotional difficulties, peer relational problems, and prosocial behaviors conditional on trajectories of conduct problems (i.e., EOP, CL and AO) from ages 4 to 13 years. At ages 7-8 years, DSM-IV-based diagnoses of conduct disorder, oppositional-defiant disorder, attention deficit/hyperactivity disorder (ADHD), anxiety, depression were examined by conduct problems trajectory. Overall, the development of hyperactivity, emotional difficulties, peer relational problems, and prosocial behaviors mirrored the development of conduct problems, showing similar trajectories. Results indicated that the problems of EOP youth were persistent across domains, CL youth showed decreased behavior problems while increasing in prosocial behaviors, and AO youth increased in adjustment problems after 10 years of age. © 2010 The Authors. Journal of Child Psychology and Psychiatry © 2010 Association for Child and Adolescent Mental Health.

  4. Conduct problems trajectories and psychosocial outcomes: a systematic review and meta-analysis.

    PubMed

    Bevilacqua, Leonardo; Hale, Daniel; Barker, Edward D; Viner, Russell

    2017-10-06

    There is increasing evidence that youth who follow the early onset persistent (EOP), adolescent-onset (AO) and childhood-limited (CL) trajectories of conduct problems show varying patterns of health, mental health, educational, and social outcomes in adulthood. However, there has been no systematic review and meta-analysis on outcomes associated with different conduct problems trajectories. We systematically reviewed the literature of longitudinal studies considering outcomes of three conduct problems trajectories: EOP, AO, and CL compared with individuals with low levels of conduct problems (low). We performed a series of meta-analyses comparing each trajectory to the low group for eight different outcomes in early adulthood or later. Thirteen studies met our inclusion criteria. Outcomes were mental health (depression), cannabis use, alcohol use, self-reported aggression, official records of antisocial behaviour, poor general health, poor education, and poor employment. Overall, EOP individuals showed significant higher risk of poor outcome followed by AO individuals, CL individuals, and finally participants in the low group. All conduct problems trajectories showed higher risk of poor psychosocial outcomes compared to the low group, but the magnitude of risk differed across trajectories, with a general trend for the EOP to perform significantly worse, followed by the AO and CL. Early intervention is recommended across domains to maximise likelihood of desistance from antisocial behaviour and improvement on several psychosocial outcomes.

  5. Circulating promyelocytes and low levels of CD16 expression on polymorphonuclear leukocytes accompany early-onset periodontitis.

    PubMed Central

    Nemoto, E; Nakamura, M; Shoji, S; Horiuchi, H

    1997-01-01

    Early-onset periodontitis (EOP) is characterized by rapidly progressive alveolar bone loss, chemotactic defects of neutrophils, and significant familial aggregation. We found immature myeloid lineage cells, defined as promyelocytes, in the peripheral blood in patients with EOP. A hematological examination of peripheral blood cells showed normal reference values regarding cell proportions. Flow cytometry revealed significantly lower expression of CD16, a glycosylphosphatidylinositol (GPI)-anchored protein, on peripheral neutrophils in patients compared with those in age- and sex-matched healthy controls, whereas the levels of CD11a and CD11b expression were similar. The chemotactic response of neutrophils was lower toward not only formyl-methionyl-leucyl-phenylalanine but also complement fragment C5a than that of healthy controls. The expression of another GPI-anchored protein, CD14, was equally expressed by controls and patients. Therefore, the low level of CD16 expression was not due to the incomplete synthesis of the GPI anchor. GPI anchors of CD16 on neutrophils from controls and patients were both partially resistant to phosphatidylinositol-specific phospholipase C. The presence of promyelocytes in peripheral blood, low expression of CD16, and low chemotactic response of neutrophils suggest that patients with EOP have an abnormal maturation system in myeloid lineage cells in the bone marrow, which may be associated with the onset and course of EOP. PMID:9284170

  6. International VLBI Service for Geodesy and Astrometry. Delivering high-quality products and embarking on observations of the next generation

    NASA Astrophysics Data System (ADS)

    Nothnagel, A.; Artz, T.; Behrend, D.; Malkin, Z.

    2017-07-01

    The International VLBI Service for Geodesy and Astrometry (IVS) regularly produces high-quality Earth orientation parameters from observing sessions employing extensive networks or individual baselines. The master schedule is designed according to the telescope days committed by the stations and by the need for dense sampling of the Earth orientation parameters (EOP). In the pre-2011 era, the network constellations with their number of telescopes participating were limited by the playback and baseline capabilities of the hardware (Mark4) correlators. This limitation was overcome by the advent of software correlators, which can now accommodate many more playback units in a flexible configuration. In this paper, we describe the current operations of the IVS with special emphasis on the quality of the polar motion results since these are the only EOP components which can be validated against independent benchmarks. The polar motion results provided by the IVS have improved continuously over the years, now providing an agreement with IGS results at the level of 20-25 μas in a WRMS sense. At the end of the paper, an outlook is given for the realization of the VLBI Global Observing System.

  7. Progressive brain changes in children and adolescents with early-onset psychosis: A meta-analysis of longitudinal MRI studies.

    PubMed

    Fraguas, David; Díaz-Caneja, Covadonga M; Pina-Camacho, Laura; Janssen, Joost; Arango, Celso

    2016-06-01

    Studies on longitudinal brain volume changes in patients with early-onset psychosis (EOP) are particularly valuable for understanding the neurobiological basis of brain abnormalities associated with psychosis. However, findings have not been consistent across studies in this population. We aimed to conduct a meta-analysis on progressive brain volume changes in children and adolescents with EOP. A systematic literature search of magnetic resonance imaging (MRI) studies comparing longitudinal brain volume changes in children and adolescents with EOP and healthy controls was conducted. The annualized rates of relative change in brain volume by region of interest (ROI) were used as raw data for the meta-analysis. The effect of age, sex, duration of illness, and specific diagnosis on volume change was also evaluated. Five original studies with 156 EOP patients (mean age at baseline MRI in the five studies ranged from 13.3 to 16.6years, 67.31% males) and 163 age- and sex-matched healthy controls, with a mean duration of follow-up of 2.46years (range 2.02-3.40), were included. Frontal gray matter (GM) was the only region in which significant differences in volume change over time were found between patients and controls (Hedges' g -0.435, 95% confidence interval (CI): -0.678 to -0.193, p<0.001). Younger age at baseline MRI was associated with greater loss of temporal GM volume over time in patients as compared with controls (p=0.005). Within patients, a diagnosis of schizophrenia was related to greater occipital GM volume loss over time (p=0.001). Compared with healthy individuals, EOP patients show greater progressive frontal GM loss over the first few years after illness onset. Age at baseline MRI and diagnosis of schizophrenia appear to be significant moderators of particular specific brain volume changes. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Development of a bi-functional silica monolith for electro-osmotic pumping and DNA clean-up/extraction using gel-supported reagents in a microfluidic device.

    PubMed

    Oakley, Jennifer A; Shaw, Kirsty J; Docker, Peter T; Dyer, Charlotte E; Greenman, John; Greenway, Gillian M; Haswell, Stephen J

    2009-06-07

    A silica monolith used to support both electro-osmotic pumping (EOP) and the extraction/elution of DNA coupled with gel-supported reagents is described. The benefits of the combined EOP extraction/elution system were illustrated by combining DNA extraction and gene amplification using the polymerase chain reaction (PCR) process. All the reagents necessary for both processes were supported within pre-loaded gels that allow the reagents to be stored at 4 degrees C for up to four weeks in the microfluidic device. When carrying out an analysis the crude sample only needed to be hydrodynamically introduced into the device which was connected to an external computer controlled power supply via platinum wire electrodes. DNA was extracted with 65% efficiency after loading lysed cells onto a silica monolith. Ethanol contained within an agarose gel matrix was then used to wash unwanted debris away from the sample by EOP (100 V cm(-1) for 5 min). The retained DNA was subsequently eluted from the monolith by water contained in a second agarose gel, again by EOP using an electric field of 100 V cm(-1) for 5 min, and transferred into the PCR reagent containing gel. The eluted DNA in solution was successfully amplified by PCR, confirming that the concept of a complete self-contained microfluidic device could be realised for DNA sample clean up and amplification, using a simple pumping and on-chip reagent storage methodology.

  9. Flow Batteries for Microfluidic Networks – Configuring An Electroosmotic Pump for Non-Terminal Positions

    PubMed Central

    He, Chiyang; Lu, Joann J.; Jia, Zhijian; Wang, Wei; Wang, Xiayan; Dasgupta, Purnendu K.; Liu, Shaorong

    2011-01-01

    A micropump provides flow and pressure for a lab-on-chip device, just as a battery supplies current and voltage for an electronic system. Numerous micropumps have been developed, but none is as versatile as a battery. One cannot easily insert a micropump into a nonterminal position of a fluidic line without affecting the rest of the fluidic system, one cannot simply connect several micropumps in series to enhance the pressure output, etc. In this work we develop a flow battery (or pressure power supply) to address this issue. A flow battery consists of a +EOP (in which the liquid flows in the same direction as the field gradient) and a −EOP (in which the liquid flows opposite to the electric field gradient), and the outlet of the +EOP is directly connected to the inlet of the −EOP. An external high voltage is applied to this outlet-inlet joint via a short gel-filled capillary that allows ions but not bulk liquid flow, while the +EOP’s inlet and the −EOP’s outlet (the flow battery’s inlet and outlet) are grounded. This flow battery can be deployed anywhere in a fluidic network without electrically affecting the rest of the system. Several flow batteries can be connected in series to enhance the pressure output to drive HPLC separations. In a fluidic system powered by flow batteries, a hydraulic Ohm’s law can be applied to analyze system pressures and flow rates. PMID:21375230

  10. Systematic Calibration for a Backpacked Spherical Photogrammetry Imaging System

    NASA Astrophysics Data System (ADS)

    Rau, J. Y.; Su, B. W.; Hsiao, K. W.; Jhan, J. P.

    2016-06-01

    A spherical camera can observe the environment for almost 720 degrees' field of view in one shoot, which is useful for augmented reality, environment documentation, or mobile mapping applications. This paper aims to develop a spherical photogrammetry imaging system for the purpose of 3D measurement through a backpacked mobile mapping system (MMS). The used equipment contains a Ladybug-5 spherical camera, a tactical grade positioning and orientation system (POS), i.e. SPAN-CPT, and an odometer, etc. This research aims to directly apply photogrammetric space intersection technique for 3D mapping from a spherical image stereo-pair. For this purpose, several systematic calibration procedures are required, including lens distortion calibration, relative orientation calibration, boresight calibration for direct georeferencing, and spherical image calibration. The lens distortion is serious on the ladybug-5 camera's original 6 images. Meanwhile, for spherical image mosaicking from these original 6 images, we propose the use of their relative orientation and correct their lens distortion at the same time. However, the constructed spherical image still contains systematic error, which will reduce the 3D measurement accuracy. Later for direct georeferencing purpose, we need to establish a ground control field for boresight/lever-arm calibration. Then, we can apply the calibrated parameters to obtain the exterior orientation parameters (EOPs) of all spherical images. In the end, the 3D positioning accuracy after space intersection will be evaluated, including EOPs obtained by structure from motion method.

  11. First-trimester mean arterial blood pressure and the risk of preeclampsia: The Great Obstetrical Syndromes (GOS) study.

    PubMed

    Gasse, Cédric; Boutin, Amélie; Coté, Maxime; Chaillet, Nils; Bujold, Emmanuel; Demers, Suzanne

    2018-04-01

    To estimate the predictive value of first-trimester mean arterial pressure (MAP) for the hypertensive disorders of pregnancy (HDP). We performed a prospective cohort study of nulliparous women recruited at 11 0/7 -13 6/7  weeks. MAP was calculated from blood pressure measured on both arms simultaneously using an automated device taking a series of recordings until blood pressure stability was reached. MAP was reported as multiples of the median adjusted for gestational age. Participants were followed for development of gestational hypertension (GH), preeclampsia (PE), preterm PE (<37 weeks) and early-onset (EO) PE (<34 weeks). Receiver operating characteristic curves and the area under the curve (AUC) were used to estimate the predictive values of MAP. Multivariate logistic regressions were used to develop predictive models combining MAP and maternal characteristics. We obtained complete follow-up in 4700 (99%) out of 4749 eligible participants. GH without PE was observed in 250 (5.3%) participants, and PE in 241 (5.1%), including 33 (0.7%) preterm PE and 10 (0.2%) EO-PE. First-trimester MAP was associated with GH (AUC: 0.77; 95%CI: 0.74-0.80); term PE (0.73; 95%CI: 0.70-0.76), preterm PE (0.80; 95%CI: 0.73-0.87) and EO-PE (0.79; 95%CI: 0.62-0.96). At a 10% false-positive rate, first-trimester MAP could have predicted 39% of GH, 34% of term PE, 48% of preterm PE and 60% of EO-PE. The addition of maternal characteristics improved the predictive values (to 40%, 37%, 55% and 70%, respectively). First-trimester MAP is a strong predictor of GH and PE in nulliparous women. Copyright © 2017 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.

  12. Assessment of State- and Territorial-Level Preparedness Capacity for Serving Deaf and Hard-of-Hearing Populations in Disasters

    PubMed Central

    Tseng, Winston; Dahrouge, Donna; Engelman, Alina; Neuhauser, Linda; Huang, Debbie; Gurung, Sidhanta

    2014-01-01

    Objectives Substantial evidence exists that emergency preparedness and response efforts are not effectively reaching populations with functional and access needs, especially barriers related to literacy, language, culture, or disabilities. More than 36 million Americans are Deaf or hard of hearing (Deaf/HH). These groups experienced higher risks of injury, death, and property loss in recent disasters than the general public. We conducted a participatory research study to examine national recommendations on preparedness communication for the Deaf/HH. Methods We assessed whether previous recommendations regarding the Deaf/HH have been incorporated into state- and territorial-level emergency operations plans (EOPs), interviewed state- and territorial-level preparedness directors about capacity to serve the Deaf/HH, and proposed strategies to benefit Deaf/HH populations during emergencies. We analyzed 55 EOPs and 50 key informant (KI) interviews with state directors. Results Fifty-five percent of EOPs mentioned vulnerable populations; however, only 31% specifically mentioned Deaf/HH populations in their plan. Study findings indicated significant relationships among the following factors: a state-level KI's familiarity with communication issues for the Deaf/HH, making relay calls (i.e., calls to services to relay communication between Deaf and hearing people), and whether the KI's department provides trainings about serving Deaf/HH populations in emergencies. We found significant associations between a state's percentage of Deaf/HH individuals and a KI's familiarity with Deaf/HH communication issues and provision by government of any disability services to Deaf/HH populations in emergencies. Further, we found significant relationships between KIs attending training on serving the Deaf/HH and familiarity with Deaf/HH communication issues, including how to make relay calls. Conclusion This study provides new knowledge that can help emergency agencies improve their preparedness training, planning, and capacity to serve Deaf/HH populations in emergencies. PMID:24587549

  13. Testing for Stray Current Corrosion in Earth Covered Magazines with EOP

    DTIC Science & Technology

    2010-02-01

    potential for Stray Current Corrosion BUILDING STRONG® Plot of Current Measurements 0 0.2 0.4 0.6 0.8 1 1.2 0 10 20 30 40 50 60 70 80 90 100 % I to Rebar m...magnitude as more current was directed to the reinforcing steel.  Corrosion current was measured to the rebar probe placed above the location of...US Army Corps of Engineers BUILDING STRONG® Testing for Stray Current Corrosion in Earth Covered Magazines with EOP O. S. Marshall US Army

  14. Historical evolution of ideas on eclampsia/preeclampsia: A proposed optimistic view of preeclampsia.

    PubMed

    Robillard, Pierre-Yves; Dekker, Gustaaf; Chaouat, Gérard; Scioscia, Marco; Iacobelli, Silvia; Hulsey, Thomas C

    2017-09-01

    Eclampsia (together with epilepsy) being the first disease ever written down since the beginning of writings in mankind 5000 years ago, we will make a brief presentation of the different major steps in comprehension of Pre-eclampsia. 1) 1840. Rayer, description of proteinuria in eclampsia, 2) 1897 Vaquez, discovery of gestational hypertension in eclamptic women, 3) In the 1970's, description of the "double" trophoblastic invasion existing only in humans (Brosens & Pijnenborg,), 4) between the 1970's and the 1990's, description of preeclampsia being a couple disease. The "paternity problem" (and therefore irruption of immunology), 5) at the end of the 1980's, a major step forward: Preeclampsia being a global endothelial cell disease (glomeruloendotheliosis, hepatic or cerebral endotheliosis, HELLP, eclampsia), inflammation (J.Roberts.C Redman, R Taylor), 6) End of the 1990's: Consensus for a distinction between early onset preeclampsia EOP and late onset LOP (34 weeks gestation), EOP being rather a problem of implantation of the trophoblast (and the placenta), LOP being rather a pre-existing maternal problem (obesity, diabetes, coagulopathies etc…). LOP is predominant everywhere on this planet, but enormously predominant in developed countries: 90% of cases. This feature is very different in countries where women have their first child very young (88% of world births), where the fatal EOP (early onset) occurs in more than 30% of cases. 7) What could be the common factor which could explain the maternal global endotheliosis in EOP and LOP? Discussion about the inositol phospho glycans P type. Copyright © 2017. Published by Elsevier B.V.

  15. Automated and dynamic scheduling for geodetic VLBI - A simulation study for AuScope and global networks

    NASA Astrophysics Data System (ADS)

    Iles, E. J.; McCallum, L.; Lovell, J. E. J.; McCallum, J. N.

    2018-02-01

    As we move into the next era of geodetic VLBI, the scheduling process is one focus for improvement in terms of increased flexibility and the ability to react with changing conditions. A range of simulations were conducted to ascertain the impact of scheduling on geodetic results such as Earth Orientation Parameters (EOPs) and station coordinates. The potential capabilities of new automated scheduling modes were also simulated, using the so-called 'dynamic scheduling' technique. The primary aim was to improve efficiency for both cost and time without losing geodetic precision, particularly to maximise the uses of the Australian AuScope VLBI array. We show that short breaks in observation will not significantly degrade the results of a typical 24 h experiment, whereas simply shortening observing time degrades precision exponentially. We also confirm the new automated, dynamic scheduling mode is capable of producing the same standard of result as a traditional schedule, with close to real-time flexibility. Further, it is possible to use the dynamic scheduler to augment the 3 station Australian AuScope array and thereby attain EOPs of the current global precision with only intermittent contribution from 2 additional stations. We thus confirm automated, dynamic scheduling bears great potential for flexibility and automation in line with aims for future continuous VLBI operations.

  16. Determination of Exterior Orientation Parameters Through Direct Geo-Referencing in a Real-Time Aerial Monitoring System

    NASA Astrophysics Data System (ADS)

    Kim, H.; Lee, J.; Choi, K.; Lee, I.

    2012-07-01

    Rapid responses for emergency situations such as natural disasters or accidents often require geo-spatial information describing the on-going status of the affected area. Such geo-spatial information can be promptly acquired by a manned or unmanned aerial vehicle based multi-sensor system that can monitor the emergent situations in near real-time from the air using several kinds of sensors. Thus, we are in progress of developing such a real-time aerial monitoring system (RAMS) consisting of both aerial and ground segments. The aerial segment acquires the sensory data about the target areas by a low-altitude helicopter system equipped with sensors such as a digital camera and a GPS/IMU system and transmits them to the ground segment through a RF link in real-time. The ground segment, which is a deployable ground station installed on a truck, receives the sensory data and rapidly processes them to generate ortho-images, DEMs, etc. In order to generate geo-spatial information, in this system, exterior orientation parameters (EOP) of the acquired images are obtained through direct geo-referencing because it is difficult to acquire coordinates of ground points in disaster area. The main process, since the data acquisition stage until the measurement of EOP, is discussed as follows. First, at the time of data acquisition, image acquisition time synchronized by GPS time is recorded as part of image file name. Second, the acquired data are then transmitted to the ground segment in real-time. Third, by processing software for ground segment, positions/attitudes of acquired images are calculated through a linear interpolation using the GPS time of the received position/attitude data and images. Finally, the EOPs of images are obtained from position/attitude data by deriving the relationships between a camera coordinate system and a GPS/IMU coordinate system. In this study, we evaluated the accuracy of the EOP decided by direct geo-referencing in our system. To perform this, we used the precisely calculated EOP through the digital photogrammetry workstation (DPW) as reference data. The results of the evaluation indicate that the accuracy of the EOP acquired by our system is reasonable in comparison with the performance of GPS/IMU system. Also our system can acquire precise multi-sensory data to generate the geo-spatial information in emergency situations. In the near future, we plan to complete the development of the rapid generation system of the ground segment. Our system is expected to be able to acquire the ortho-image and DEM on the damaged area in near real-time. Its performance along with the accuracy of the generated geo-spatial information will also be evaluated and reported in the future work.

  17. On-Line Model-Based System For Nuclear Plant Monitoring

    NASA Astrophysics Data System (ADS)

    Tsoukalas, Lefteri H.; Lee, G. W.; Ragheb, Magdi; McDonough, T.; Niziolek, F.; Parker, M.

    1989-03-01

    A prototypical on-line model-based system, LASALLE1, developed at the University of Illinois in collaboration with the Illinois Department of Nuclear Safety (IDNS) is described. Its main purpose is to interpret about 300 signals, updated every two minutes at IDNS from the LaSalle Nuclear Power Plant, and to diagnose possible abnormal conditions. It is written in VAX/VMS OPS5 and operates on both the on-line and testing modes. In its knowledge base, operator and plant actions pertaining to the Emergency Operating Procedure(EOP) A-01, are encoded. This is a procedure driven by a reactor's coolant level and pressure signals; with the purpose of shutting down the reactor, maintaining adequate core cooling and reducing the reactor pressure and temperature to cold shutdown conditions ( about 90 to 200 °F). The monitoring of the procedure is performed from the perspective of Emergency Preparedness. Two major issues are addressed in this system. First, the management of the short-term or working memory of the system. LASALLE1 must reach its inferences, display its conclusion and update a message file every two minutes before a new set of data arrives from the plant. This was achieved by superimposing additional layers of control over the inferencing strategies inherent in OPS5, and developing special rules for the management of the used or outdated information. The second issue is the representation of information and its uncertainty. The concepts of information granularity and performance-level, which are based on a coupling of Probability Theory and the theory of Fuzzy Sets, are used for this purpose. The estimation of the performance-level incorporates a mathematical methodology which accounts for two types of uncertainty encountered in monitoring physical systems: Random uncertainty, in the form of of probability density functions generated by observations, measurements and sensors data and fuzzy uncertainty represented by membership functions based on symbolic , stochastic or numerical models estimating the "plausible", "possible" or "expected" values of the system parameters. Examples from both the on-line mode and the testing mode of the system will be discussed to illustrate the present methodology.

  18. Improving the Accuracy of Direct Geo-referencing of Smartphone-Based Mobile Mapping Systems Using Relative Orientation and Scene Geometric Constraints.

    PubMed

    Alsubaie, Naif M; Youssef, Ahmed A; El-Sheimy, Naser

    2017-09-30

    This paper introduces a new method which facilitate the use of smartphones as a handheld low-cost mobile mapping system (MMS). Smartphones are becoming more sophisticated and smarter and are quickly closing the gap between computers and portable tablet devices. The current generation of smartphones are equipped with low-cost GPS receivers, high-resolution digital cameras, and micro-electro mechanical systems (MEMS)-based navigation sensors (e.g., accelerometers, gyroscopes, magnetic compasses, and barometers). These sensors are in fact the essential components for a MMS. However, smartphone navigation sensors suffer from the poor accuracy of global navigation satellite System (GNSS), accumulated drift, and high signal noise. These issues affect the accuracy of the initial Exterior Orientation Parameters (EOPs) that are inputted into the bundle adjustment algorithm, which then produces inaccurate 3D mapping solutions. This paper proposes new methodologies for increasing the accuracy of direct geo-referencing of smartphones using relative orientation and smartphone motion sensor measurements as well as integrating geometric scene constraints into free network bundle adjustment. The new methodologies incorporate fusing the relative orientations of the captured images and their corresponding motion sensor measurements to improve the initial EOPs. Then, the geometric features (e.g., horizontal and vertical linear lines) visible in each image are extracted and used as constraints in the bundle adjustment procedure which correct the relative position and orientation of the 3D mapping solution.

  19. Improving the Accuracy of Direct Geo-referencing of Smartphone-Based Mobile Mapping Systems Using Relative Orientation and Scene Geometric Constraints

    PubMed Central

    Alsubaie, Naif M.; Youssef, Ahmed A.; El-Sheimy, Naser

    2017-01-01

    This paper introduces a new method which facilitate the use of smartphones as a handheld low-cost mobile mapping system (MMS). Smartphones are becoming more sophisticated and smarter and are quickly closing the gap between computers and portable tablet devices. The current generation of smartphones are equipped with low-cost GPS receivers, high-resolution digital cameras, and micro-electro mechanical systems (MEMS)-based navigation sensors (e.g., accelerometers, gyroscopes, magnetic compasses, and barometers). These sensors are in fact the essential components for a MMS. However, smartphone navigation sensors suffer from the poor accuracy of global navigation satellite System (GNSS), accumulated drift, and high signal noise. These issues affect the accuracy of the initial Exterior Orientation Parameters (EOPs) that are inputted into the bundle adjustment algorithm, which then produces inaccurate 3D mapping solutions. This paper proposes new methodologies for increasing the accuracy of direct geo-referencing of smartphones using relative orientation and smartphone motion sensor measurements as well as integrating geometric scene constraints into free network bundle adjustment. The new methodologies incorporate fusing the relative orientations of the captured images and their corresponding motion sensor measurements to improve the initial EOPs. Then, the geometric features (e.g., horizontal and vertical linear lines) visible in each image are extracted and used as constraints in the bundle adjustment procedure which correct the relative position and orientation of the 3D mapping solution. PMID:28973958

  20. Hazard Assessment Computer System HACS/UIM Users’ Operation Manual. Volume II.

    DTIC Science & Technology

    1981-09-01

    AMMONIUM OXALATE FAS FERROUS AMMONIUM SULFATE FCL FERRIC CHLORIDE FCP FERRIC GLYCEROPHOSPHATE FEC FERROUS CHLORIDE FFA FURFURAL FFB FERROUS FLUOROBORATE...FAL FFA FFBi FMA FNS FSA FSL FXX BAK GAT SAY SCM GCR GCS SOC SOS SPL SRF GSR STA J-2 HAC HAI HAL HEIR HCC HCL HCN HDC HE’S HDZ HFA HFX HMD HMI HPA...ENP EOEI EOP EOT EPC ETA ETC ETD ETf3 ETI FAL FFA FFB FMA FMS VSL OCR GOS GIA MAC HAI HCL Ht’Z HFA HMD HMI HPA HPdkt HPO HSS HXG IAA IAC IAL IAN IBR

  1. Protective Effects of Pinus halepensis L. Essential Oil on Aspirin-induced Acute Liver and Kidney Damage in Female Wistar Albino Rats.

    PubMed

    Bouzenna, Hafsia; Samout, Noura; Amani, Etaya; Mbarki, Sakhria; Tlili, Zied; Rjeibi, Ilhem; Elfeki, Abdelfattah; Talarmin, Hélène; Hfaiedh, Najla

    2016-08-01

    Aromatic and medicinal plants are sources of natural antioxidants thanks to their secondary metabolites. Administration of Pinus halepensis L. (Pinaceae family) in previous studies was found to alleviate deleterious effects of aspirin-induced damage on liver and kidney. The present study, carried out on female rats, evaluates the effects of P. halepensis L. essential oil (EOP) on aspirin (A)-induced damage to liver and kidney. The animals used in this study were rats (n=28) divided into 4 groups of 7 each: (1) a control group (C); (2) a group given NaCl for 56 days then treated with (A) (600 mg/kg) for 4 days (A); (3) a group fed with (EOP) for 56 days then (A) for 4 days; and a group fed with only (EOP) for 56 days and given NaCl for 4 days. Estimations of biochemical parameters in blood were determined using kit methods (Spinreact). Lipid peroxidation levels (TBARS), superoxide dismutase (SOD) and catalase (CAT), glutathione peroxidase (GPx) activities were determined. Histopathological study was done by immersing pieces of both organs in a fixative solution followed by paraffin embeddeding and hematoxylin-eosin staining. Under our experimental conditions, Aspirin at dose 600 mg/kg body weight induced an increase of serum biochemical parameters as well as an oxidative stress in both organs. An increase occurred in TBARS by 108% and 55%, a decrease in SOD by 78% and 53%, CAT by 53% and 78%, and GPx by 78% and 51% in liver and kidney, respectively, compared to control. Administration of EOP given to rats enabled correction in these parameters. It could be concluded that the treatment with P. halepensis L. essential oil inhibited aspirin-induced liver and kidney damage.

  2. El Nino, La Nina and VLBI Measured LOD

    NASA Technical Reports Server (NTRS)

    Clark, Thomas A.; Gipson, J. M.; Ma, C.

    1998-01-01

    VLBI is one of the most important techniques for measuring Earth orientation parameters (EOP), and is unique in its ability to make high accuracy measurements of UT1, and its time derivative, which is related to changes in the length of day, conventionally called LOD. These measurements of EOP give constraints on geophysical models of the solid-Earth, atmosphere and oceans. Changes in EOP are due either to external torques from gravitational forces, or to the exchange of angular momentum between the Earth, atmosphere and oceans. The effect of the external torques is strictly harmonic and nature, and is therefore easy to remove. We analyze an LOD time series derived from VLBI measurements with the goal of comparing this to predictions from AAM, and various ENSO indices. Previous work by ourselves and other investigators demonstrated a high degree of coherence between atmospheric angular momentum (AAM) and EOP. We continue to see this. As the angular momentum of the atmosphere increases, the rate of rotation of the Earth decreases, and vice versa. The signature of the ENSO is particularly strong. At the peak of the 1982-83 El Nino increased LOD by almost 1 ms. This was subsequently followed by a reduction in LOD of 0.75 ms. At its peak, in February of 1998, the 1997-98 El Nino increased LOD by 0.8 msec. As predicted at the 1998 Spring AGU, this has been followed by an abrupt decrease in LOD which is currently -0.4 ms. At this time (August, 1998) the current ENSO continues to develop in new and unexpected ways. We plan to update our analysis with all data available prior to the Fall AGU.

  3. Comparative study of clinical and neuropsychological characteristics between early-, late and very-late-onset schizophrenia-spectrum disorders.

    PubMed

    Hanssen, Manon; van der Werf, Margriet; Verkaaik, Mike; Arts, Baer; Myin-Germeys, Inez; van Os, Jim; Verhey, Frans; Köhler, Sebastian

    2015-08-01

    To compare the clinical and neurocognitive profile of early-onset (EOP, <40 years), late-onset (LOP, 40-59 years) and very-late-onset (VLOP, ≥60 years) psychosis. Cross-sectional observational study. Secondary, tertiary, and community mental health care. Patients with a DSM-IV diagnosis of non-affective psychotic disorder were included from two complementary studies (GROUP and PSITE) on genetic and environmental risk factors of psychosis in the Netherlands and Belgium. Main outcome measures were the severity of positive and negative symptoms, quality of life, and age-corrected scores on measures of general intelligence, verbal memory, attention, and executive function. One-year follow-up data were used to validate diagnoses and exclude participants with possible or probable dementia. 286 EOP (85%), 24 LOP (7%) and 28 VLOP (8%) participated. VLOP patients reported significantly more positive symptoms than EOP patients. Age-at-onset groups had similar age-corrected scores on IQ, verbal memory, attention and executive functions. A significantly better performance was found in VLOP compared with LOP on the CAMCOG total score, though scores were still within the normal range. After controlling for possible confounding, however, VLOP differed significantly on an attention accuracy task compared with LOP patients. Re-entering data for probable dementia patients (N = 4) did change the results regarding cognition outcomes. VLOP patients show more positive symptoms but do not appear to differ on neuropsychological tests from EOP and LOP when age is controlled for. This questions the idea that VLOP is the expression of underlying neurodegeneration. Copyright © 2015 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.

  4. Subdaily alias and draconitic errors in the IGS orbits

    NASA Astrophysics Data System (ADS)

    Griffiths, J.; Ray, J.

    2011-12-01

    Harmonic signals with a fundamental period near the GPS draconitic year (351.2 d) and overtones up to the 8th multiple have been observed in the power spectra of nearly all products of the International GNSS Service (IGS), including station position time series [Ray et al., 2008; Collilieux et al., 2007; Santamaría-Gómez et al., 2011], apparent geocenter motions [Hugentobler et al., 2008], and orbit jumps between successive days and midnight discontinuities in Earth orientation parameter (EOP) rates [Ray and Griffiths, 2009]. Ray et al. [2008] suggested two mechanisms for the harmonics: mismodeling of orbit dynamics and aliasing of near-sidereal local station multipath effects. King and Watson [2010] have studied the propagation of local multipath errors into draconitic position variations, but orbit-related processes have been less well examined. Here we elaborate our earlier analysis of GPS orbit jumps [Griffiths and Ray, 2009; Gendt et al., 2010] where we observed some draconitic features as well as prominent spectral bands near 29, 14, 9, and 7 d periods. Finer structures within the sub-seasonal bands fall close to the expected alias frequencies of subdaily EOP tide lines but do not coincide precisely. While once-per-rev empirical orbit parameters should strongly absorb any subdaily EOP tide errors due to near-resonance of their respective periods, the observed differences require explanation. This has been done by simulating known EOP tidal errors and checking their impact on a long series of daily GPS orbits. Indeed, simulated tidal aliases are found to be very similar to the observed orbital features in the sub-seasonal bands. Moreover and unexpectedly, some low draconitic harmonics were also stimulated, potentially a source for the widespread errors in most IGS products.

  5. S-Esters of Thiohydroximic Acid Esters - A Novel Class of Cholinesterase Reactivators.

    DTIC Science & Technology

    1981-01-05

    Hammet substituent constant ( p)63 is also linear and conforms to equation (5) pKa - (7.63 ±0.02) - 0.63 ±0.05) a (5) p These correlations provide an...of AChE reactivation and it is recognized6, 7 that the reaction proceeds as shown in equation (1) EOP + R [EOP9R] kr P EOH + ROP (1) H20 where: EOH is...conforms to equation (4) pKa (25.3 ±2.1) - (1.36 ±0.16) 6 (4) For the aroylthiohydroximates (SR 2458, 2460, and 2461) a plot (not shown) of pKa versus

  6. Automatic registration of panoramic image sequence and mobile laser scanning data using semantic features

    NASA Astrophysics Data System (ADS)

    Li, Jianping; Yang, Bisheng; Chen, Chi; Huang, Ronggang; Dong, Zhen; Xiao, Wen

    2018-02-01

    Inaccurate exterior orientation parameters (EoPs) between sensors obtained by pre-calibration leads to failure of registration between panoramic image sequence and mobile laser scanning data. To address this challenge, this paper proposes an automatic registration method based on semantic features extracted from panoramic images and point clouds. Firstly, accurate rotation parameters between the panoramic camera and the laser scanner are estimated using GPS and IMU aided structure from motion (SfM). The initial EoPs of panoramic images are obtained at the same time. Secondly, vehicles in panoramic images are extracted by the Faster-RCNN as candidate primitives to be matched with potential corresponding primitives in point clouds according to the initial EoPs. Finally, translation between the panoramic camera and the laser scanner is refined by maximizing the overlapping area of corresponding primitive pairs based on the Particle Swarm Optimization (PSO), resulting in a finer registration between panoramic image sequences and point clouds. Two challenging urban scenes were experimented to assess the proposed method, and the final registration errors of these two scenes were both less than three pixels, which demonstrates a high level of automation, robustness and accuracy.

  7. Analysis of Differences Between VLBI, GNSS and SLR Earth Orientation Series

    NASA Astrophysics Data System (ADS)

    MacMillan, D. S.; Pavlis, E. C.; Griffiths, J.

    2016-12-01

    We have compared polar motion series from VLBI, GNSS, and SLR where the reference frames were aligned to ITRF2008. Three objectives of the comparisons are 1) to determine biases between the techniques and 2) to determine the precisions of each technique via a 3-corner hat analysis after removing the relative biases, and 3) to evaluate the long-term stability of EOP series. Between VLBI and GPS or SLR, there are clear annual variations ranging from 25 to 100 µas in peak-to-peak amplitude. We investigate the possible causes of these variations. In addition, there are other apparent systematic bias and rate differences. From the point of view of VLBI, it is evident that there are VLBI network dependent effects, specifically between the operational R1 and R4 weekly 24-hour sessions. We investigate the origins of these differences including network station changes in these networks over the period from 2002-present. The EOP biases and precisions of the five IVS VLBI CONT campaigns (since 2002) are also analyzed since these sessions were each designed to provide the highest quality results that could be produced at the time. A possible source of biases between the geodetic techniques is the underlying reference frame used by each technique. We also consider the technique differences when ITRF2014 was applied instead of ITRF2008.

  8. Working towards a zero waste environment in Taiwan.

    PubMed

    Young, Chea-Yuan; Ni, Shih-Piao; Fan, Kuo-Shuh

    2010-03-01

    It is essential to the achievement of zero waste that emphasis is concentrated on front-end preventions rather than end-of-pipe (EOP) treatment. Zero waste is primarily based on cleaner production, waste management, the reduction of unnecessary consumption and the effective utilization of waste materials. The aim of this study was to briefly review the tasks undertaken and future plans for achieving zero waste in Taiwan. Waste prevention, source reduction, waste to product, waste to energy, EOP treatment, and adequate disposal are the sequential principal procedures to achieve the goal of zero waste. Six strategies have been adopted to implement the zero waste policy in Taiwan. These are regulatory amendments, consumption education, financial incentives, technical support, public awareness, and tracking and reporting. Stepwise targets have been set for 2005, 2007, 2011, and 2020 for both the municipal solid waste (MSW) and industrial waste to reach the goal of zero waste. The eventual aim is to achieve 70% MSW minimization and 85% industrial waste minimization by 2020. Although tools and measures have been established, some key programmes have higher priority. These include the establishment of a waste recycling programme, promotion of cleaner production, a green procurement programme, and promotion of public awareness. Since the implementation of the zero waste policy started in 2003, the volume of MSW for landfill and incineration has declined dramatically. The recycling and/or minimization of MSW quantity in 2007 was 37%, which is much higher than the goal of 25%. Industrial waste reached almost 76% minimization by the end of 2006, which is 1 year before the target year.

  9. Interaction Between the Celestial and the Terrestrial Reference Frames

    NASA Technical Reports Server (NTRS)

    Gordon, David; MacMillan, Dan; Bolotin, Sergei; Le Bail, Karine; Gipson, John; Ma, Chopo

    2010-01-01

    Effects of International Celestial Reference Frame (ICRF2) on the Terrestrial Reference Frames (TRF), CRF and EOP's, The ICRF2 became official on Jan. 1, 2010. It includes positions of 3414 compact radio astronomical sources observed with VLBI, a fivefold increase from the first ICRF. Numerous new VLBI models were used and the most unstable sources were treated as arc parameters to avoid distortions of the frame. The ICRF2 has a noise floor of 40 micro-arc-seconds and an axis stability of 10 micro-arc-seconds. It was aligned with the ICRS using 138 stable sources common to ICRF2 and ICRF-Ext2. Maintenance of ICRF2 is to be made using 295 defining sources chosen for their historical positional stability, minimal source structure, and sky distribution. Their stability and their more uniform sky distribution eliminate the two largest weaknesses of ICRF I. The switchover to ICRF2 has some small effects on the TRF, CRF and Earth Orientation Parameters (EOP). A CRF based on ICRF2 shows a relative rotation of 40 micro-arc-seconds, mostly about the Y-axis. Small shifts are also seen in the EOP's, the largest being 11 micro-arc-seconds in X-pole. Some small but insignificant differences are also seen in the TRF. These results will be presented and discussed.

  10. Time series of low-degree geopotential coefficients from SLR data: estimation of Earth's figure axis and LOD variations

    NASA Astrophysics Data System (ADS)

    Luceri, V.; Sciarretta, C.; Bianco, G.

    2012-12-01

    The redistribution of the mass within the earth system induces changes in the Earth's gravity field. In particular, the second-degree geopotential coefficients reflect the behaviour of the Earth's inertia tensor of order 2, describing the main mass variations of our planet impacting the EOPs. Thanks to the long record of accurate and continuous laser ranging observations to Lageos and other geodetic satellites, SLR is the only current space technique capable to monitor the long time variability of the Earth's gravity field with adequate accuracy. Time series of low-degree geopotential coefficients are estimated with our analysis of SLR data (spanning more than 25 years) from several geodetic satellites in order to detect trends and periodic variations related to tidal effects and atmospheric/oceanic mass variations. This study is focused on the variations of the second-degree Stokes coefficients related to the Earth's principal figure axis and oblateness: C21, S21 and C20. On the other hand, surface mass load variations induce excitations in the EOPs that are proportional to the same second-degree coefficients. The time series of direct estimates of low degree geopotential and those derived from the EOP excitation functions are compared and presented together with their time and frequency analysis.

  11. Direct Retrieval of Exterior Orientation Parameters Using A 2-D Projective Transformation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seedahmed, Gamal H.

    2006-09-01

    Direct solutions are very attractive because they obviate the need for initial approximations associated with non-linear solutions. The Direct Linear Transformation (DLT) establishes itself as a method of choice for direct solutions in photogrammetry and other fields. The use of the DLT with coplanar object space points leads to a rank deficient model. This rank deficient model leaves the DLT defined up to a 2-D projective transformation, which makes the direct retrieval of the exterior orientation parameters (EOPs) a non-trivial task. This paper presents a novel direct algorithm to retrieve the EOPs from the 2-D projective transformation. It is basedmore » on a direct relationship between the 2-D projective transformation and the collinearity model using homogeneous coordinates representation. This representation offers a direct matrix correspondence between the 2-D projective transformation parameters and the collinearity model parameters. This correspondence lends itself to a direct matrix factorization to retrieve the EOPs. An important step in the proposed algorithm is a normalization process that provides the actual link between the 2-D projective transformation and the collinearity model. This paper explains the theoretical basis of the proposed algorithm as well as the necessary steps for its practical implementation. In addition, numerical examples are provided to demonstrate its validity.« less

  12. Combining selection valve and mixing chamber for nanoflow gradient generation: Toward developing a liquid chromatography cartridge coupled with mass spectrometer for protein and peptide analysis.

    PubMed

    Chen, Apeng; Lu, Joann J; Gu, Congying; Zhang, Min; Lynch, Kyle B; Liu, Shaorong

    2015-08-05

    Toward developing a micro HPLC cartridge, we have recently built a high-pressure electroosmotic pump (EOP). However, we do not recommend people to use this pump to deliver an organic solvent directly, because it often makes the pump rate unstable. We have experimented several approaches to address this issue, but none of them are satisfactory. Here, we develop an innovative approach to address this issue. We first create an abruption (a dead-volume) within a fluid conduit. We then utilize an EOP to withdraw, via a selection valve, a train of eluent solutions having decreasing eluting power into the fluid conduit. When these solutions are further aspirated through the dead-volume, these solutions are partially mixed, smoothening concentration transitions between two adjacent eluent solutions. As these solutions are pushed back, through the dead-volume again, a smooth gradient profile is formed. In this work, we characterize this scheme for gradient formation, and we incorporate this approach with a high-pressure EOP, a nanoliter injection valve, and a capillary column, yielding a micro HPLC system. We then couple this micro HPLC with an electrospray ionization - mass spectrometer for peptide and protein separations and identifications. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. A Toolkit For CryoSat Investigations By The ESRIN EOP-SER Altimetry Team

    NASA Astrophysics Data System (ADS)

    Dinardo, Salvatore; Bruno, Lucas; Benveniste, Jerome

    2013-12-01

    The scope of this work is to feature the new tool for the exploitation of the CryoSat data, designed and developed entirely by the Altimetry Team at ESRIN EOP-SER (Earth Observation - Exploitation, Research and Development). The tool framework is composed of two separate components: the first one handles the data collection and management, the second one is the processing toolkit. The CryoSat FBR (Full Bit Rate) data is downlinked uncompressed from the satellite, containing un-averaged individual echoes. This data is made available in the Kiruna CalVal server in a 10 day rolling archive. Daily at ESRIN all the CryoSat FBR data, in SAR and SARin Mode, are downloaded (around 30 Gigabytes) catalogued and archived in local ESRIN EOP-SER workstations. As of March 2013, the total amount of FBR data is over 9 Terabytes, with CryoSat acquisition dates spanning January 2011 to February 2013 (with some gaps). This archive was built by merging partial datasets available at ESTEC and NOAA, that have been kindly made available for EOP-SER team. The on-demand access to this low level data is restricted to expert users with validated ESA P.I. credentials. Currently the main users of the archiving functionality are the team members of the Project CP4O (STSE- CryoSat Plus for Ocean), CNES and NOAA. The second component of the service is the processing toolkit. On the EOP-SER workstations there is internally and independently developed software that is able to process the FBR data in SAR/SARin mode to generate multi-looked echoes (Level 1B) and subsequently able to re-track them in SAR and SARin mode (Level 2) over open ocean, exploiting the SAMOSA model and other internally developed models. The processing segment is used for research & development scopes, supporting the development contracts awarded confronting the deliverables to ESA, on site demonstrations/training to selected users, cross- comparison against third part products (CLS/CNES CPP Products for instance), preparation to Sentinel-3 mission, publications, etc. Samples of these experimental SAR/SARin L1b/L2 Products can be provided to the scientific community for comparison with self-processed data, on-request. So far, the processing has been designed and optimized for open ocean studies and is fully functional only over this kind of surface but there are plans to augment this processing capacity over coastal zones, inland waters and over land in sight of maximizing the exploitation of the upcoming Sentinel-3 Topographic mission over all surfaces. There are also plans to make the toolkit fully accessible through software “gridification” to run in the ESRin GPod (Grid Processing on Demand) Service and to extend the tool's functionalities to support Sentinel-3 Mission (both Simulated and Real Data). Graphs and statistics about the spatial coverage and amount of FBR data actually archived on the EOP-SER workstations and some scientific results will be shown in this paper along with the tests that have been designed and performed to validate the products (tests against CryoSat Kiruna PDGS Products and against transponder data).

  14. Global and regional kinematics with VLBI

    NASA Technical Reports Server (NTRS)

    Ma, Chopo

    1994-01-01

    Since a VLBI station cannot operate in isolation and since simultaneous operation of the entire VLBI network is impractical, it is necessary to design observing programs with periodic observing sessions using networks of 3-7 stations that, when treated together, will have the necessary interstation data and network overlaps to determine the desired rates of change. Thus, there has been a mix of global, intercontinental, transcontinental, and regional networks to make measurements ranging from plate motions to deformation over a few hundred km. Over time, even networks focusing on regional deformation using mobile VLBI included large stations removed by several thousand km to increase sensitivity, determine EOP more accurately, and provide better ties to the terrestrial reference frame (TRF). Analysis products have also evolved, beginning with baseline components, and then to full three-dimensional site velocities in a global TRF.

  15. 5 CFR 1312.10 - Systematic review guidelines.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., DOWNGRADING, DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Classification and Declassification of National Security Information § 1312.10 Systematic review guidelines. The EOP Security Officer...

  16. Automatic digital surface model (DSM) generation from aerial imagery data

    NASA Astrophysics Data System (ADS)

    Zhou, Nan; Cao, Shixiang; He, Hongyan; Xing, Kun; Yue, Chunyu

    2018-04-01

    Aerial sensors are widely used to acquire imagery for photogrammetric and remote sensing application. In general, the images have large overlapped region, which provide a lot of redundant geometry and radiation information for matching. This paper presents a POS supported dense matching procedure for automatic DSM generation from aerial imagery data. The method uses a coarse-to-fine hierarchical strategy with an effective combination of several image matching algorithms: image radiation pre-processing, image pyramid generation, feature point extraction and grid point generation, multi-image geometrically constraint cross-correlation (MIG3C), global relaxation optimization, multi-image geometrically constrained least squares matching (MIGCLSM), TIN generation and point cloud filtering. The image radiation pre-processing is used in order to reduce the effects of the inherent radiometric problems and optimize the images. The presented approach essentially consists of 3 components: feature point extraction and matching procedure, grid point matching procedure and relational matching procedure. The MIGCLSM method is used to achieve potentially sub-pixel accuracy matches and identify some inaccurate and possibly false matches. The feasibility of the method has been tested on different aerial scale images with different landcover types. The accuracy evaluation is based on the comparison between the automatic extracted DSMs derived from the precise exterior orientation parameters (EOPs) and the POS.

  17. Monitoring of Earth Rotation by VLBI

    NASA Technical Reports Server (NTRS)

    Ma., Chopo; Macmillan, D. S.

    2000-01-01

    Monitoring Earth rotation with Very Long Baseline Interferometry (VLBI) has unique potential because of direct access to the Celestial Reference System (CRF and Terrestrial Reference System (TRF) and the feasibility of re-analyzing the entire data set. While formal precision of better than 0.045 mas for pole and 0.002 ms for UT 1 has been seen in the best 24-hr data, the accuracy of the Earth Orientation Parameter (EOP) time series as a whole is subject to logistical, operational, analytical and conceptual constraints. The current issues related to the VLBI data set and the CORE program for greater time resolution such as analysis consistency, network jitter and reference frame stability will be discussed.

  18. Host exopolysaccharide quantity and composition impact Erwinia amylovora bacteriophage pathogenesis.

    PubMed

    Roach, Dwayne R; Sjaarda, David R; Castle, Alan J; Svircev, Antonet M

    2013-05-01

    Erwinia amylovora bacteriophages (phages) belonging to the Myoviridae and Podoviridae families demonstrated a preference for either high-exopolysaccharide-producing (HEP) or low-exopolysaccharide-producing (LEP) bacterial hosts when grown on artificial medium without or with sugar supplementation. Myoviridae phages produced clear plaques on LEP hosts and turbid plaques on HEP hosts. The reverse preference was demonstrated by most Podoviridae phages, where clear plaques were seen on HEP hosts. Efficiency of plating (EOP) was determined by comparing phage growth on the original isolation host to the that on the LEP or HEP host. Nine of 10 Myoviridae phages showed highest EOPs on LEP hosts, and 8 of 11 Podoviridae phages had highest EOPs on HEP hosts. Increasing the production of EPS on sugar-supplemented medium or decreasing production by knocking out the synthesis of amylovoran or levan, the two EPSs produced by E. amylovora, indicated that these components play crucial roles in phage infection. Amylovoran was virtually essential for proliferation of most Podoviridae phages when phage population growth was compared to the wild type. Decreased levan production resulted in a significant reduction of progeny from phages in the Myoviridae family. Thus, Podoviridae phages are adapted to hosts that produce high levels of exopolysaccharides and are dependent on host-produced amylovoran for pathogenesis. Myoviridae phages are adapted to hosts that produce lower levels of exopolysaccharides and host-produced levan.

  19. Host Exopolysaccharide Quantity and Composition Impact Erwinia amylovora Bacteriophage Pathogenesis

    PubMed Central

    Roach, Dwayne R.; Sjaarda, David R.; Svircev, Antonet M.

    2013-01-01

    Erwinia amylovora bacteriophages (phages) belonging to the Myoviridae and Podoviridae families demonstrated a preference for either high-exopolysaccharide-producing (HEP) or low-exopolysaccharide-producing (LEP) bacterial hosts when grown on artificial medium without or with sugar supplementation. Myoviridae phages produced clear plaques on LEP hosts and turbid plaques on HEP hosts. The reverse preference was demonstrated by most Podoviridae phages, where clear plaques were seen on HEP hosts. Efficiency of plating (EOP) was determined by comparing phage growth on the original isolation host to the that on the LEP or HEP host. Nine of 10 Myoviridae phages showed highest EOPs on LEP hosts, and 8 of 11 Podoviridae phages had highest EOPs on HEP hosts. Increasing the production of EPS on sugar-supplemented medium or decreasing production by knocking out the synthesis of amylovoran or levan, the two EPSs produced by E. amylovora, indicated that these components play crucial roles in phage infection. Amylovoran was virtually essential for proliferation of most Podoviridae phages when phage population growth was compared to the wild type. Decreased levan production resulted in a significant reduction of progeny from phages in the Myoviridae family. Thus, Podoviridae phages are adapted to hosts that produce high levels of exopolysaccharides and are dependent on host-produced amylovoran for pathogenesis. Myoviridae phages are adapted to hosts that produce lower levels of exopolysaccharides and host-produced levan. PMID:23503310

  20. Earth Orientation and Its Excitations by Atmosphere, Oceans, and Geomagnetic Jerks

    NASA Astrophysics Data System (ADS)

    Vondrák, J.; Ron, C.

    2015-12-01

    In addition to torques exerted by the Moon, Sun, and planets, changes of the Earth orientation parameters (EOP) are known to be caused also by excitations by the atmosphere and oceans. Recently appeared studies, hinting that geomagnetic jerks (GMJ, rapid changes of geomagnetic field) might be associated with sudden changes of phase and amplitude of EOP (Holme and de Viron 2005, 2013, Gibert and Le Mouël 2008, Malkin 2013). We (Ron et al. 2015) used additional excitations applied at the epochs of GMJ to derive its influence on motion of the spin axis of the Earth in space (precession-nutation). We demonstrated that this effect, if combined with the influence of the atmosphere and oceans, improves substantially the agreement with celestial pole offsets observed by Very Long-Baseline Interferometry. Here we concentrate our efforts to study possible influence of GMJ on temporal changes of all five Earth orientation parameters defining the complete Earth orientation in space. Numerical integration of Brzeziński's broad-band Liouville equations (Brzeziński 1994) with atmospheric and oceanic excitations, combined with expected GMJ effects, is used to derive EOP and compare them with their observed values. We demonstrate that the agreement between all five Earth orientation parameters integrated by this method and those observed by space geodesy is improved substantially if the influence of additional excitations at GMJ epochs is added to excitations by the atmosphere and oceans.

  1. External factors impacting hospital evacuations caused by Hurricane Rita: the role of situational awareness.

    PubMed

    Downey, Erin L; Andress, Knox; Schultz, Carl H

    2013-06-01

    The 2005 Gulf Coast hurricane season was one of the most costly and deadly in US history. Hurricane Rita stressed hospitals and led to multiple, simultaneous evacuations. This study systematically identified community factors associated with patient movement out of seven hospitals evacuated during Hurricane Rita. This study represents the second of two systematic, observational, and retrospective investigations of seven acute care hospitals that reported off-site evacuations due to Hurricane Rita. Participants from each hospital included decision makers that comprised the Incident Management Team (IMT). Investigators applied a standardized interview process designed to assess evacuation factors related to external situational awareness of community activities during facility evacuation due to hurricanes. The measured outcomes were responses to 95 questions within six sections of the survey instrument. Investigators identified two factors that significantly impacted hospital IMT decision making: (1) incident characteristics affecting a facility's internal resources and challenges; and (2) incident characteristics affecting a facility's external evacuation activities. This article summarizes the latter and reports the following critical decision making points: (1) Emergency Operations Plans (EOP) were activated an average of 85 hours (3 days, 13 hours) prior to Hurricane Rita's landfall; (2) the decision to evacuate the hospital was made an average of 30 hours (1 day, 6 hours) from activation of the EOP; and (3) the implementation of the evacuation process took an average of 22 hours. Coordination of patient evacuations was most complicated by transportation deficits (the most significant of the 11 identified problem areas) and a lack of situational awareness of community response activities. All evacuation activities and subsequent evacuation times were negatively impacted by an overall lack of understanding on the part of hospital staff and the IMT regarding how to identify and coordinate with community resources. Hospital evacuation requires coordinated processes and resources, including situational awareness that reflects the condition of the community as a result of the incident. Successful hospital evacuation decision making is influenced by community-wide situational awareness and transportation deficits. Planning with the community to create realistic EOPs that accurately reflect available resources and protocols is critical to informing hospital decision making during a crisis. Knowledge of these factors could improve decision making and evacuation practices, potentially reducing evacuation times in future hurricanes.

  2. 4-station ultra-rapid EOP experiment with e-VLBI technique and automated correlation/analysis

    NASA Astrophysics Data System (ADS)

    Kurihara, S.; Nozawa, K.; Haas, R.; Lovell, J.; McCallum, J.; Quick, J.; Hobiger, T.

    2013-08-01

    Since 2007, the Geospatial Information Authority of Japan (GSI) and the Onsala Space Observatory (OSO) have performed the ultra-rapid dUT1 experiments, which can provide us with near real-time dUT1 value. Its technical knowledge has already been adopted for the regular series of the Tsukuba-Wettzell intensive session. Now we tried some 4-station ultra-rapid EOP experiments in association with Hobart and HartRAO so that we can estimate not only dUT1 but also the two polar motion parameters. In this experiment a new analysis software c5++ developed by the National Institute of Information and Communications Technology (NICT) was used. We describe past developments and an overview of the experiment, and conclude with its results in this report.

  3. Investigation of 1 : 1,000 Scale Map Generation by Stereo Plotting Using Uav Images

    NASA Astrophysics Data System (ADS)

    Rhee, S.; Kim, T.

    2017-08-01

    Large scale maps and image mosaics are representative geospatial data that can be extracted from UAV images. Map drawing using UAV images can be performed either by creating orthoimages and digitizing them, or by stereo plotting. While maps generated by digitization may serve the need for geospatial data, many institutions and organizations require map drawing using stereoscopic vision on stereo plotting systems. However, there are several aspects to be checked for UAV images to be utilized for stereo plotting. The first aspect is the accuracy of exterior orientation parameters (EOPs) generated through automated bundle adjustment processes. It is well known that GPS and IMU sensors mounted on a UAV are not very accurate. It is necessary to adjust initial EOPs accurately using tie points. For this purpose, we have developed a photogrammetric incremental bundle adjustment procedure. The second aspect is unstable shooting conditions compared to aerial photographing. Unstable image acquisition may bring uneven stereo coverage, which will result in accuracy loss eventually. Oblique stereo pairs will create eye fatigue. The third aspect is small coverage of UAV images. This aspect will raise efficiency issue for stereo plotting of UAV images. More importantly, this aspect will make contour generation from UAV images very difficult. This paper will discuss effects relate to these three aspects. In this study, we tried to generate 1 : 1,000 scale map from the dataset using EOPs generated from software developed in-house. We evaluated Y-disparity of the tie points extracted automatically through the photogrammetric incremental bundle adjustment process. We could confirm that stereoscopic viewing is possible. Stereoscopic plotting work was carried out by a professional photogrammetrist. In order to analyse the accuracy of the map drawing using stereoscopic vision, we compared the horizontal and vertical position difference between adjacent models after drawing a specific model. The results of analysis showed that the errors were within the specification of 1 : 1,000 map. Although the Y-parallax can be eliminated, it is still necessary to improve the accuracy of absolute ground position error in order to apply this technique to the actual work. There are a few models in which the difference in height between adjacent models is about 40 cm. We analysed the stability of UAV images by checking angle differences between adjacent images. We also analysed the average area covered by one stereo model and discussed the possible difficulty associated with this narrow coverage. In the future we consider how to reduce position errors and improve map drawing performances from UAVs.

  4. Monitoring global climate change using SLR data from LARES and other geodetic satellites

    NASA Astrophysics Data System (ADS)

    Paolozzi, Antonio; Paris, Claudio; Pavlis, Erricos C.; Sindoni, Giampiero; Ciufolini, Ignazio

    2016-04-01

    The Earth Orientation Parameters (EOP), i.e. the spin axis of the Earth, is influenced by the mass redistribution inside and on the surface of the Earth. On the Earth surface, global ice melting, sea level change and atmospheric circulation are the prime contributors. Recent studies have unraveled the majority of the mysteries behind the Chandler wobble, the annual motion and the secular motion of the pole. The differences from the motion of a pole for a rigid Earth is indeed due to the mass redistribution and transfer of angular momentum among the atmosphere, the oceans and solid Earth. The technique of laser ranging and the use of laser ranged satellites such as LARES along with other techniques such Very Long Baseline Interferometry (VLBI) allow to measure the EOP with accuracies at the level of ~200 μas which correspond to few millimeters at the Earth's surface, while the use of Global Navigation Satellite System (GNSS) data can reach an accuracy even below 100 μas. At these unprecedented high levels of accuracy, even tiny anomalous behavior in EOP can be observed and thus correlated to global environmental changes such as ice melting on Greenland and the polar caps, and extreme events that involve strong ocean-atmosphere coupling interactions such as the El Niño. The contribution of Satellite Laser Ranging (SLR) data such as from the LARES mission and similar satellites to this area is outlined in this paper.

  5. Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes.

    PubMed

    Tsuzuki, Hirofumi; Arinobu, Yojiro; Miyawaki, Kohta; Takaki, Ayako; Ota, Shun-Ichiro; Ota, Yuri; Mitoma, Hiroki; Akahoshi, Mitsuteru; Mori, Yasuo; Iwasaki, Hiromi; Niiro, Hiroaki; Tsukamoto, Hiroshi; Akashi, Koichi

    2017-01-01

    Interleukin-33 (IL-33) induces T helper type 2 (Th2) cytokine production and eosinophilia independently of acquired immunity, leading to innate immunity-mediated allergic inflammation. Allergy-related innate myeloid cells such as eosinophils, basophils and mast cells express the IL-33 receptor (IL-33R), but it is still unknown how IL-33 regulates allergic inflammation involving these cells and their progenitors. Here, we revealed that the functional IL-33R was expressed on eosinophil progenitors (EoPs), basophil progenitors (BaPs) and mast cell progenitors (MCPs). In the presence of IL-33, these progenitors did not expand, but produced a high amount of Th2 and pro-inflammatory cytokines such as IL-9, IL-13, IL-1β and IL-6. The amount of cytokines produced by these progenitors was greater than that by mature cells. In vivo, IL-33 stimulated the expansion of EoPs, but it was dependent upon the elevated serum IL-5 that is presumably derived from type 2 innate lymphoid cells that express functional IL-33R. These data collectively suggest that EoPs, BaPs and MCPs are not only the sources of allergy-related granulocytes, but can also be sources of allergy-related cytokines in IL-33-induced inflammation. Because such progenitors can differentiate into mature granulocytes at the site of inflammation, they are potential therapeutic targets in IL-33-related allergic diseases. © 2016 John Wiley & Sons Ltd.

  6. [Early onset pneumonia after successful resuscitation : Incidence after mild invasive hypothermia therapy].

    PubMed

    Erath, J W; Hodrius, J; Bushoven, P; Fichtlscherer, S; Zeiher, A M; Seeger, F H; Honold, J

    2017-09-01

    Targeted temperature management (TTM) represents an effective therapy to improve neurologic outcome in patients who survive an out-of-hospital cardiac arrest (OHCA). First publications about this therapy reported a higher incidence of infections in patients who underwent TTM induced by external cooling devices. Whether intravascular cooling devices are also associated with an increased infection rate has not been investigated so far. In a single center retrospective study, the incidence of early onset pneumonia (EOP) in OHCA patients with or without intravascular TTM at 33 °C target temperature for 24 h who survived at least 24 h after admission was analyzed. A total of 68 OHCA survivors (mean age 65 ± 15 years) were included in this analysis. The most common causes of OHCA were myocardial infarction (35 %), primary ventricular fibrillation (24 %), asystole (15 %), and pulmonary embolism (7 %). Of those, 32 patients (48 %) received TTM. The overall incidence of EOP was 38 %. Incidence of EOP did not differ significantly between groups, was more frequent in the group without TTM (42 % vs. 34 %, p = 0.57) and had no impact on mortality (hazard ratio = 1.02; 95 % confidence interval 0.25-4.16; p = 0.97). Intravascular TTM at 33 °C with a cooling catheter is not associated with more infective complications in OHCA patients. This finding underscores the safety of TTM.

  7. Improving Polar Motion Predictions Using AAM χ1 and χ2 Forecasts

    NASA Astrophysics Data System (ADS)

    Ratcliff, J. T.; Gross, R. S.

    2017-12-01

    The uncertainty in our knowledge of the Earth's changing orientation in space is a majorsource of error in tracking and navigating interplanetary spacecraft. Because the Earth'sorientation changes rapidly and unpredictably, measurements must be acquired frequentlyand processed rapidly in order to meet the near-real-time Earth orientation requirements ofthe interplanetary spacecraft navigation teams. The Kalman Earth Orientation Filter (KEOF)is used to combine GPS polar motion and LOD measurements, Very Long Baseline Interferometry(VLBI) polar motion and UT measurements, along with other publicly available Earth orientationmeasurements including proxy measurements such as atmospheric angular momentum (AAM),in order to generate and deliver the required polar motion and UT1 Earth orientation parametersto the spacecraft navigation teams. Short-term predictions of the EOPs are produced in order toprovide the navigation teams with an uninterrupted series of Earth orientation parameters. WhileAAM 𝜒3 forecasts are used as a proxy LOD forecast to improve UT1 predictions, Polar Motionpredictions had not been similarly treated. In order to evaluate the effectiveness off AAM 𝜒1 and 𝜒2forecasts on improving Polar Motion predictions we reprocessed one year (Jan.-Dec. 2015) of EOP measurementsto include the 𝜒1 and 𝜒2 components of National Centers for Environmental Prediction (NCEP)AAM daily 5-day forecasts. Inclusion of AAM 𝜒1 and 𝜒2 forecasts into EOP predictions was foundto improve the accuracy of the Polar Motion 5-day predictions by 33% in the X-component and 34% in the Y-component.

  8. 5 CFR 1312.11 - Challenges to classifications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., DOWNGRADING, DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Classification and Declassification of National Security Information § 1312.11 Challenges to classifications. OMB employees are... anonymous, in which case the question may be directed to the EOP Security Officer. ...

  9. Volunteering in the Elementary Outreach Program Could Make You Happier | Poster

    Cancer.gov

    By Marsha Nelson-Duncan, Guest Writer, and Nancy Parrish, Staff Writer Did you know that volunteers in the Elementary Outreach Program (EOP) just might be happier than their coworkers who don’t volunteer?

  10. 5 CFR 1312.11 - Challenges to classifications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., DOWNGRADING, DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Classification and Declassification of National Security Information § 1312.11 Challenges to classifications. OMB employees are... anonymous, in which case the question may be directed to the EOP Security Officer. ...

  11. Building a Future for Technological Innovation

    DTIC Science & Technology

    2010-08-17

    breakthroughs in health IT • Address scientific “grand challenges” Promote Competitive Markets that Spur Productive Entrepreneurship • Promote... entrepreneurship • Improve public sector innovation and support community innovation Source: http://www.whitehouse.gov/administration/eop/nec/reports

  12. Long-Term Variations of the EOP and ICRF2

    NASA Technical Reports Server (NTRS)

    Zharov, Vladimir; Sazhin, Mikhail; Sementsov, Valerian; Sazhina, Olga

    2010-01-01

    We analyzed the time series of the coordinates of the ICRF radio sources. We show that part of the radio sources, including the defining sources, shows a significant apparent motion. The stability of the celestial reference frame is provided by a no-net-rotation condition applied to the defining sources. In our case this condition leads to a rotation of the frame axes with time. We calculated the effect of this rotation on the Earth orientation parameters (EOP). In order to improve the stability of the celestial reference frame we suggest a new method for the selection of the defining sources. The method consists of two criteria: the first one we call cosmological and the second one kinematical. It is shown that a subset of the ICRF sources selected according to cosmological criteria provides the most stable reference frame for the next decade.

  13. Long-term mass variations from SLR, VLBI and GPS data

    NASA Astrophysics Data System (ADS)

    Luceri, Vincenza; Sciarretta, Cecilia; Bianco, Giuseppe

    2013-04-01

    The second-degree geopotential coefficients reflect the behaviour of the Earth's inertia tensor of order 2 which describes the main mass variations of our planet impacting polar motion and length of day (EOP). SLR, VLBI and GPS allow the estimation of those variations, either directly in the case of SLR through its dynamics, and indirectly, for all the three geodetic techniques, by deriving excitation functions from the EOP estimations. The geodetic estimates include the influence of the Earth's atmosphere and oceans, both from their mass and motion components, which can be modelled using the atmospheric and oceanic angular momenta variations. The different C21, S21 and C20 geodetic time series are compared in order to evaluate their coherence and their response to the mass variations after the removal of the motion terms. Moreover, the residual signal contents of the geodetic values, deprived by the atmospheric and oceanic mass and motion components, will be investigated.

  14. Reference Frames in Earth Rotation Theories

    NASA Astrophysics Data System (ADS)

    Ferrándiz, José M.; Belda, Santiago; Heinkelmann, Robert; Getino, Juan; Schuh, Harald; Escapa, Alberto

    2015-04-01

    Nowadays the determination of the Earth Orientation Parameters (EOP) and the different Terrestrial Reference Frames (TRF) are not independent. The available theories of Earth rotation aims at providing the orientation of a certain reference system linked somehow to the Earth with respect to a given celestial system, considered as inertial. In the past years a considerable effort has been dedicated to the improvement of the TRF realizations, following the lines set up in the 1980's. However, the reference systems used in the derivation of the theories have been rather considered as something fully established, not deserving a special attention. In this contribution we review the definitions of the frames used in the main theoretical approaches, focusing on those used in the construction of IAU2000, and the extent to which their underlying hypotheses hold. The results are useful to determine the level of consistency of the predicted and determined EOP.

  15. 5 CFR 1312.22 - Responsibilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... computer systems meeting the appropriate security criteria. (a) EOP Security Officer. In cooperation with..., DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Control and Accountability of Classified... duty by employees will do much to ensure the adequate security of classified information in the...

  16. 5 CFR 1312.22 - Responsibilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... computer systems meeting the appropriate security criteria. (a) EOP Security Officer. In cooperation with..., DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Control and Accountability of Classified... duty by employees will do much to ensure the adequate security of classified information in the...

  17. 5 CFR 1312.22 - Responsibilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... computer systems meeting the appropriate security criteria. (a) EOP Security Officer. In cooperation with..., DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Control and Accountability of Classified... duty by employees will do much to ensure the adequate security of classified information in the...

  18. 5 CFR 1312.22 - Responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... computer systems meeting the appropriate security criteria. (a) EOP Security Officer. In cooperation with..., DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Control and Accountability of Classified... duty by employees will do much to ensure the adequate security of classified information in the...

  19. 5 CFR 1312.22 - Responsibilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... computer systems meeting the appropriate security criteria. (a) EOP Security Officer. In cooperation with..., DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Control and Accountability of Classified... duty by employees will do much to ensure the adequate security of classified information in the...

  20. 75 FR 50033 - Generalized System of Preferences (GSP): Notice Extending Deadline for Submission of Petitions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... announced in the Federal Register at a later date. FOR FURTHER INFORMATION CONTACT: Tameka Cooper, GSP... is Tameka_Cooper@ustr.eop.gov . Public versions of the petitions submitted will be available for...

  1. CPO Prediction: Accuracy Assessment and Impact on UT1 Intensive Results

    NASA Technical Reports Server (NTRS)

    Malkin, Zinovy

    2010-01-01

    The UT1 Intensive results heavily depend on the celestial pole offset (CPO) model used during data processing. Since accurate CPO values are available with a delay of two to four weeks, CPO predictions are necessarily applied to the UT1 Intensive data analysis, and errors in the predictions can influence the operational UT1 accuracy. In this paper we assess the real accuracy of CPO prediction using the actual IERS and PUL predictions made in 2007-2009. Also, results of operational processing were analyzed to investigate the actual impact of EOP prediction errors on the rapid UT1 results. It was found that the impact of CPO prediction errors is at a level of several microseconds, whereas the impact of the inaccuracy in the polar motion prediction may be about one order of magnitude larger for ultra-rapid UT1 results. The situation can be amended if the IERS Rapid solution will be updated more frequently.

  2. The International Celestial Reference Frame (ICRF) and the Relationship Between Frames

    NASA Technical Reports Server (NTRS)

    Ma, Chopo

    2000-01-01

    The International Celestial Reference Frame (ICRF), a catalog of VLBI source positions, is now the basis for astrometry and geodesy. Its construction and extension/maintenance will be discussed as well as the relationship of the ICRF, ITRF, and EOP/nutation.

  3. 75 FR 54939 - Generalized System of Preferences (GSP): Notice Changing the Date of the Country Practices Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ....m. FOR FURTHER INFORMATION CONTACT: Tameka Cooper, GSP Program, Office of the United States Trade... fax number is (202) 395-2961, and the e-mail address is Tameka_Cooper@ustr.eop.gov . Elena Bryan...

  4. Precise Orbital and Geodetic Parameter Estimation using SLR Observations for ILRS AAC

    NASA Astrophysics Data System (ADS)

    Kim, Young-Rok; Park, Eunseo; Oh, Hyungjik Jay; Park, Sang-Young; Lim, Hyung-Chul; Park, Chandeok

    2013-12-01

    In this study, we present results of precise orbital geodetic parameter estimation using satellite laser ranging (SLR) observations for the International Laser Ranging Service (ILRS) associate analysis center (AAC). Using normal point observations of LAGEOS-1, LAGEOS-2, ETALON-1, and ETALON-2 in SLR consolidated laser ranging data format, the NASA/ GSFC GEODYN II and SOLVE software programs were utilized for precise orbit determination (POD) and finding solutions of a terrestrial reference frame (TRF) and Earth orientation parameters (EOPs). For POD, a weekly-based orbit determination strategy was employed to process SLR observations taken from 20 weeks in 2013. For solutions of TRF and EOPs, loosely constrained scheme was used to integrate POD results of four geodetic SLR satellites. The coordinates of 11 ILRS core sites were determined and daily polar motion and polar motion rates were estimated. The root mean square (RMS) value of post-fit residuals was used for orbit quality assessment, and both the stability of TRF and the precision of EOPs by external comparison were analyzed for verification of our solutions. Results of post-fit residuals show that the RMS of the orbits of LAGEOS-1 and LAGEOS-2 are 1.20 and 1.12 cm, and those of ETALON-1 and ETALON-2 are 1.02 and 1.11 cm, respectively. The stability analysis of TRF shows that the mean value of 3D stability of the coordinates of 11 ILRS core sites is 7.0 mm. An external comparison, with respect to International Earth rotation and Reference systems Service (IERS) 08 C04 results, shows that standard deviations of polar motion XP and YP are 0.754 milliarcseconds (mas) and 0.576 mas, respectively. Our results of precise orbital and geodetic parameter estimation are reasonable and help advance research at ILRS AAC.

  5. Win–Win strategies to promote air pollutant control policies and non-fossil energy target regulation in China

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Lining; Patel, Pralit L.; Yu, Sha

    The rapid growth of energy consumption in China has led to increased emissions of air pollutants. As a response, in its 12th Five Year Plan the Chinese government proposed mitigation targets for SO2 and NOx emissions. Herein we have investigated mitigation measures taken in different sectors and their corresponding impacts on the energy system. Additionally, as non-fossil energy development has gained traction in addressing energy and environmental challenges in China, we further investigated the impact of non-fossil energy development on air pollutant emissions, and then explored interactions and co-benefits between these two types of policies. An extended Global Change Assessmentmore » Model (GCAM) was used in this study, which includes an additional air pollutant emissions control module coupling multiple end-of-pipe (EOP) control technologies with energy technologies, as well as more detailed end-use sectors in China. We find that implementing EOP control technologies would reduce air pollution in the near future, but with little room left to implement these EOP technologies, other cleaner and more efficient technologies are also effective. These technologies would reduce final energy consumption, increase electricity’s share in final energy, and increase the share of non-fossil fuels in primary energy and electricity consumption. Increasing non-fossil energy usage at China’s proposed adoption rate would in turn also reduce SO2 and NOx emissions, however, the reductions from this policy alone still lag behind the targeted requirements of air pollutant reduction. Fortunately, a combination of air pollutant controls and non-fossil energy development could synergistically help realize the respective individual targets, and would result in lower costs than would addressing these issues separately.« less

  6. Isolation of Phages for Phage Therapy: A Comparison of Spot Tests and Efficiency of Plating Analyses for Determination of Host Range and Efficacy

    PubMed Central

    Khan Mirzaei, Mohammadali; Nilsson, Anders S.

    2015-01-01

    Phage therapy, treating bacterial infections with bacteriophages, could be a future alternative to antibiotic treatment of bacterial infections. There are, however, several problems to be solved, mainly associated to the biology of phages, the interaction between phages and their bacterial hosts, but also to the vast variation of pathogenic bacteria which implies that large numbers of different phages are going to be needed. All of these phages must under present regulation of medical products undergo extensive clinical testing before they can be applied. It will consequently be of great economic importance that effective and versatile phages are selected and collected into phage libraries, i.e., the selection must be carried out in a way that it results in highly virulent phages with broad host ranges. We have isolated phages using the Escherichia coli reference (ECOR) collection and compared two methods, spot testing and efficiency of plating (EOP), which are frequently used to identify phages suitable for phage therapy. The analyses of the differences between the two methods show that spot tests often overestimate both the overall virulence and the host range and that the results are not correlated to the results of EOP assays. The conclusion is that single dilution spot tests cannot be used for identification and selection of phages to a phage library and should be replaced by EOP assays. The difference between the two methods can be caused by many factors. We have analysed if the differences and lack of correlation could be caused by lysis from without, bacteriocins in the phage lysate, or by the presence of prophages harbouring genes coding for phage resistance systems in the genomes of the bacteria in the ECOR collection. PMID:25761060

  7. Lymphatic vascular endothelial hyaluronan receptor-1 immunoexpression in placenta of HIV infected pre-eclamptic women.

    PubMed

    Onyangunga, Onankoy A; Moodley, Jagidesa; Merhar, Vesselina; Ofusori, David A; Naicker, Thajasvarie

    2016-09-01

    Lymphangiogenesis is the formation of new vessels from pre-existing lymphatic vessels. Data on lymphangiogenesis in the placenta of HIV-infected pre-eclamptics are sparse and the findings are conflicting. The aim of this novel study was to evaluate LYVE-1 immunoexpression in the placenta of HIV infected normotensive versus pre-eclamptic women. Placental tissue was obtained from normotensive and pre-eclamptic women stratified according to their HIV status. The pre-eclamptic group was divided into early (<34 weeks) and late (>34 weeks) onset. Immunohistochemistry utilized mouse anti-human LYVE-1 antibody and was morphometrically evaluated. LYVE-1 immunostaining was localized within endothelium of the arterial supply and venous drainage of both conducting and exchange villi as well as within medial cells of arteries. LYVE-1 immunostained macrophage-like cells were observed within the fetal and maternal circulation. LYVE-1 immunoexpression was higher (p=0.0001) in HIV positive cohort, regardless of pregnancy and villous type. Irrespective of HIV status and pregnancy type, LYVE-1 immunoexpression was significantly elevated in the conducting compared to the exchange villi (p=0.01). LYVE-1 immunoexpression was higher in N and LOPE compared to EOPE groups for both conducting and exchange villi types respectively (p=0.0001 and p=0.006). There is a decrease of LYVE-1 expression in EOPE+ (conducting villi) and EOPE- (exchange villi) compared to N and LOPE subgroups. This study provides a novel insight into an up-regulation of LYVE-1 expression in the fetal circulation of conducting and exchange villi of HIV-infected pre-eclamptics. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  8. Matching Aerial Images to 3D Building Models Using Context-Based Geometric Hashing

    PubMed Central

    Jung, Jaewook; Sohn, Gunho; Bang, Kiin; Wichmann, Andreas; Armenakis, Costas; Kada, Martin

    2016-01-01

    A city is a dynamic entity, which environment is continuously changing over time. Accordingly, its virtual city models also need to be regularly updated to support accurate model-based decisions for various applications, including urban planning, emergency response and autonomous navigation. A concept of continuous city modeling is to progressively reconstruct city models by accommodating their changes recognized in spatio-temporal domain, while preserving unchanged structures. A first critical step for continuous city modeling is to coherently register remotely sensed data taken at different epochs with existing building models. This paper presents a new model-to-image registration method using a context-based geometric hashing (CGH) method to align a single image with existing 3D building models. This model-to-image registration process consists of three steps: (1) feature extraction; (2) similarity measure; and matching, and (3) estimating exterior orientation parameters (EOPs) of a single image. For feature extraction, we propose two types of matching cues: edged corner features representing the saliency of building corner points with associated edges, and contextual relations among the edged corner features within an individual roof. A set of matched corners are found with given proximity measure through geometric hashing, and optimal matches are then finally determined by maximizing the matching cost encoding contextual similarity between matching candidates. Final matched corners are used for adjusting EOPs of the single airborne image by the least square method based on collinearity equations. The result shows that acceptable accuracy of EOPs of a single image can be achievable using the proposed registration approach as an alternative to a labor-intensive manual registration process. PMID:27338410

  9. UT/CSR analysis of earth rotation from Lageos SLR data

    NASA Technical Reports Server (NTRS)

    Tapley, B. D.; Eanes, R. J.; Schutz, B. E.

    1986-01-01

    The 1983-1984 data collected by NASA and stations participating in the Crustal Dynamics Project from satellite laser ranging (SLR) systems are used to generate solutions for the earth polar motion. Solutions obtained using the MERIT Lageos standard data set are compared to operational results based on quick-look data and generated in near real-time, and the capability of Lageos SLR for the determination of earth orientation parameters (EOP) with high temporal resolution is investigated. Finally, the sensitivity of the MERIT campaign results to the number of tracking stations and to changes in the MERIT standard model is evaluated. It is concluded that the departures from the IAU/IUGG MERIT standards do not significantly change the solution and that solutions accurate at the 2 milliarcsec level can be maintained with a network of fewer than 10 appropriately selected stations.

  10. 75 FR 48585 - Revision of Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... Service Center and Reading Room; electronic FOIA requests; access to records published or released under... Disclosure Reading Room at: http://www.whitehouse.gov/administration/eop/ceq/foia/readingroom . In general... resources, particularly its Proactive Disclosure Reading Room, should be used to advance NEPA's goals of...

  11. 5 CFR 1312.10 - Systematic review guidelines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Systematic review guidelines. 1312.10... Declassification of National Security Information § 1312.10 Systematic review guidelines. The EOP Security Officer will prepare and keep current such guidelines as are required by Executive Order 12958 for the...

  12. Erwinia amylovora effector protein Eop1 suppresses PAMP-triggered immunity in Malus

    USDA-ARS?s Scientific Manuscript database

    Erwinia amylovora (Ea) utilizes a type three secretion system (T3SS) to deliver effector proteins into plant host cells. Several Ea effectors have been identified based on their sequence similarity to plant and animal bacterial pathogen effectors; however, the function of the majority of Ea effecto...

  13. 32 CFR 2402.2 - Delegation of authority and responsibilities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... 2402.2 Section 2402.2 National Defense Other Regulations Relating to National Defense OFFICE OF SCIENCE... authority and responsibilities. (a) The Director of the Office of Science and Technology Policy designates...://www.whitehouse.gov/administration/eop/ostp) and may re-delegate the FOIA Public Liaison's authority at...

  14. 76 FR 34745 - Notice of Submission of Proposed Information Collection to OMB, Emergency Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ...-mail: oir submission @omb.eop.gov; fax: 202- 395-3086. FOR FURTHER INFORMATION CONTACT: Reports... of available documents submitted to OMB may be obtained from the Reports Management Officer.../Update Report (``HUD Applicant Recipient Disclosure Report'' on Grants.gov ). (e) Form SF-LLL--Disclosure...

  15. 7 CFR 1980.445 - Periodic financial statements and audits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... accordance with approriate Office of Management and Budget (OMB) circulars and any Agency requirements... receivable for collateral will normally be audited, regardless of the size of the loan. Nothing in this... the Office of Management and Budget, EOP Publications Office, 725 17th Street, NW., Room 2200, New...

  16. 7 CFR 1980.445 - Periodic financial statements and audits.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... accordance with approriate Office of Management and Budget (OMB) circulars and any Agency requirements... receivable for collateral will normally be audited, regardless of the size of the loan. Nothing in this... the Office of Management and Budget, EOP Publications Office, 725 17th Street, NW., Room 2200, New...

  17. 7 CFR 1980.445 - Periodic financial statements and audits.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... accordance with approriate Office of Management and Budget (OMB) circulars and any Agency requirements... receivable for collateral will normally be audited, regardless of the size of the loan. Nothing in this... the Office of Management and Budget, EOP Publications Office, 725 17th Street, NW., Room 2200, New...

  18. 7 CFR 1980.445 - Periodic financial statements and audits.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... accordance with approriate Office of Management and Budget (OMB) circulars and any Agency requirements... receivable for collateral will normally be audited, regardless of the size of the loan. Nothing in this... the Office of Management and Budget, EOP Publications Office, 725 17th Street, NW., Room 2200, New...

  19. 7 CFR 1980.445 - Periodic financial statements and audits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... accordance with approriate Office of Management and Budget (OMB) circulars and any Agency requirements... receivable for collateral will normally be audited, regardless of the size of the loan. Nothing in this... the Office of Management and Budget, EOP Publications Office, 725 17th Street, NW., Room 2200, New...

  20. 5 CFR 1312.27 - Top secret control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Top secret control. 1312.27 Section 1312... Classified Information § 1312.27 Top secret control. The EOP Security Officer serves as the Top Secret... Top Secret material. The ATSCOs will be responsible for the accountability and custodianship of Top...

  1. 5 CFR 1312.27 - Top secret control.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Top secret control. 1312.27 Section 1312... Classified Information § 1312.27 Top secret control. The EOP Security Officer serves as the Top Secret... Top Secret material. The ATSCOs will be responsible for the accountability and custodianship of Top...

  2. 5 CFR 1312.27 - Top secret control.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Top secret control. 1312.27 Section 1312... Classified Information § 1312.27 Top secret control. The EOP Security Officer serves as the Top Secret... Top Secret material. The ATSCOs will be responsible for the accountability and custodianship of Top...

  3. 5 CFR 1312.27 - Top secret control.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Top secret control. 1312.27 Section 1312... Classified Information § 1312.27 Top secret control. The EOP Security Officer serves as the Top Secret... Top Secret material. The ATSCOs will be responsible for the accountability and custodianship of Top...

  4. 5 CFR 1312.27 - Top secret control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Top secret control. 1312.27 Section 1312... Classified Information § 1312.27 Top secret control. The EOP Security Officer serves as the Top Secret... Top Secret material. The ATSCOs will be responsible for the accountability and custodianship of Top...

  5. 5 CFR 1312.25 - Storage.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Storage. 1312.25 Section 1312.25... Information § 1312.25 Storage. All classified material in the possession of OMB will be stored in a GSA-approved container or in vault-type rooms approved for Top Secret storage. Under the direction of the EOP...

  6. 5 CFR 1312.25 - Storage.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Storage. 1312.25 Section 1312.25... Information § 1312.25 Storage. All classified material in the possession of OMB will be stored in a GSA-approved container or in vault-type rooms approved for Top Secret storage. Under the direction of the EOP...

  7. 5 CFR 1312.25 - Storage.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Storage. 1312.25 Section 1312.25... Information § 1312.25 Storage. All classified material in the possession of OMB will be stored in a GSA-approved container or in vault-type rooms approved for Top Secret storage. Under the direction of the EOP...

  8. 5 CFR 1312.25 - Storage.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Storage. 1312.25 Section 1312.25... Information § 1312.25 Storage. All classified material in the possession of OMB will be stored in a GSA-approved container or in vault-type rooms approved for Top Secret storage. Under the direction of the EOP...

  9. 5 CFR 1312.25 - Storage.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Storage. 1312.25 Section 1312.25... Information § 1312.25 Storage. All classified material in the possession of OMB will be stored in a GSA-approved container or in vault-type rooms approved for Top Secret storage. Under the direction of the EOP...

  10. Pulkovo IVS Analysis Center (PUL) 2012 Annual Report

    NASA Technical Reports Server (NTRS)

    Malkin, Zinovy; Sokolova, Julia

    2013-01-01

    This report briefly presents the PUL IVS Analysis Center activities during 2012 and plans for the coming year. The main topics of the investigations of PUL staff in that period were ICRF related studies, computation and analysis of EOP series, celestial pole offset (CPO) modeling, and VLBI2010 related issues.

  11. Partnering with IT to Help Disadvantaged Students Achieve Academic Success

    ERIC Educational Resources Information Center

    Clarke, Janet H.

    2012-01-01

    This case study will describe how the Stony Brook University Libraries instruction program partnered with another student support service (student computing office) to nurture a relationship with the Educational Opportunities Program (EOP) over several years to provide their students with the library research and computer skills needed to succeed…

  12. Air Pollutant Emissions Projections for the Cement and Steel Industry in China and the Impact of Emissions Control Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hasanbeigi, Ali; Khanna, Nina; Price, Lynn

    China’s cement and steel industry accounts for approximately half of the world’s total cement and steel production. These two industries are two of the most energy-intensive and highest carbon dioxide (CO 2)-emitting industries and two of the key industrial contributors to air pollution in China. For example, the cement industry is the largest source of particulate matter (PM) emissions in China, accounting for 40 percent of its industrial PM emissions and 27 percent of its total national PM emissions. The Chinese steel industry contributed to approximately 20 percent of sulfur dioxide (SO 2) emissions and 27 percent of PM emissionsmore » for all key manufacturing industries in China in 2013. In this study, we analyzed and projected the total PM and SO2 emissions from the Chinese cement and steel industry from 2010–2050 under three different scenarios: a Base Case scenario, an Advanced scenario, and an Advanced EOP (end-of-pipe) scenario. We used bottom-up emissions control technologies data and assumptions to project the emissions. In addition, we conducted an economic analysis to estimate the cost for PM emissions reductions in the Chinese cement industry using EOP control technologies, energy efficiency measures, and product change measures. The results of the emissions projection showed that there is not a substantial difference in PM emissions between the Base Case and Advanced scenarios, for both the cement and steel industries. This is mainly because PM emissions in the cement industry caused mainly by production process and not the fuel use. Since our forecast for the cement production in the Base Case and Advanced scenarios are not too different from each other, this results in only a slight difference in PM emissions forecast for these two scenarios. Also, we assumed a similar share and penetration rate of control technologies from 2010 up to 2050 for these two scenarios for the cement and steel industry. However, the Advanced EOP scenario showed significantly lower PM emissions for the cement industry, reaching to 1.7 million tons of PM in 2050, which is less than half of that in the other two scenarios. The Advanced EOP scenario also has the lowest SO2 emissions for the cement industry in China, reaching to 212,000 tons of SO2 in 2050, which is equal to 40 percent of the SO2 emissions in the Advanced scenario and 30 percent of the emissions in the Base Case scenario. The SO2 emission is mainly caused by fuel (coal) burning in cement kiln or steel processes. For the steel industry, the SO2 emissions of the Advanced EOP scenario are significantly lower than the other scenarios, with emissions declining to 323,000 tons in 2050, which is equal to 21 percent and 17 percent of the emissions of Advanced and Base Case scenarios in 2050, respectively. Results of the economic analysis show that for the Chinese cement industry, end-of-pipe PM control technologies have the lowest abatement cost per ton of PM reduced, followed by product change measures and energy efficiency measures, respectively. In summary, in order to meet Chinese national and regional air quality standards, best practice end-of-pipe emissions control technologies must be installed in both cement and steel industry and it must be supplemented by implementation of energy efficiency technologies and reduction of cement and steel production through structural change in industry.« less

  13. Co-Occurring Problems of Early Onset Persistent, Childhood Limited, and Adolescent Onset Conduct Problem Youth

    ERIC Educational Resources Information Center

    Barker, Edward D.; Oliver, Bonamy R.; Maughan, Barbara

    2010-01-01

    Background: It is increasingly recognized that youth who follow early onset persistent (EOP), childhood limited (CL) and adolescent onset (AO) trajectories of conduct problems show somewhat varying patterns of risk (in childhood) and adjustment problems (in adolescence and adulthood). Little, however, is known about how other adjustment problems…

  14. 75 FR 30024 - Notice of Public Information Collection Being Reviewed by the Federal Communications Commission...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-28

    ....eop.gov and to the Federal Communications Commission via email to [email protected] and Cathy.Williams@fcc.gov . FOR FURTHER INFORMATION CONTACT: For additional information, contact Cathy Williams on (202) 418-2918. SUPPLEMENTARY INFORMATION: OMB Number: 3060-0180. Title: Section 73.1610, Equipment Tests. Form...

  15. 77 FR 30318 - Agency Information Collection Activities: 30-Day Notice of Intention To Request Clearance of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ....eop.gov or fax at 202-395-5806; and identify your submission as 1024-0018, Nomination of Properties... properties have significance to the history of communities, states, or the Nation. The National Historic..., and to establish criteria and guidelines for including properties on the National Register. National...

  16. 78 FR 42064 - Before Commissioners: Jon Wellinghoff, Chairman; Philip D. Moeller, John R. Norris, Cheryl A...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-15

    ... reporting is ``an ex post activity'' that provides only prospective benefits to system reliability.\\14... Section 215, and those obligations that do not, such as administrative record-keeping and ex- post... EOP-004-2 becomes effective. Finally, we approve the proposed violation risk factors and violation...

  17. 76 FR 58803 - Commission Information Collection Activities (FERC-725A); Comment Request; Submitted for OMB Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ... in Docket No. RD11-4-000 under the requirements of FERC-725A, ``Mandatory Reliability Standards for the Bulk-Power System'' (OMB No. 1902-0244), is required by Commission-approved Reliability Standard EOP-008-1 (Loss of Control Center Functionality) that requires reliability coordinators, transmission...

  18. 78 FR 58295 - Commission Information Collection Activities (FERC-725A); Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... submitting the information collection FERC-725A, Mandatory Reliability Standards for the Bulk Power System... collection analysis associated with its approval of Reliability Standard EOP-004-2, in an order published in... solicitation and is making this notation in its submission to OMB. \\1\\ North American Electric Reliability Corp...

  19. When K Through 12 Is Not Enough: Preparing At-Risk Highschoolers for College.

    ERIC Educational Resources Information Center

    Sedlak Valerie, F.

    A college-high school-business partnership was developed in Maryland between Morgan State University (an historically black institution), Lake Clifton/Eastern high school (a predominantly black high school), and local businessmen representing the Educational Opportunity Program (EOP) in an effort to begin preparing high school ninth graders for…

  20. Extended Opportunity Programs and Services (EOPS): A Quantitative Study of Latino Students' Goal Completion

    ERIC Educational Resources Information Center

    Barraza, Bertha

    2012-01-01

    A problem exists with consistency in measuring and tracking students' academic goals in California Community Colleges [CCC]. Effective measurements in CCC that embody academic goals below the associate degree and four-year college articulation agreements, call for attention to determine student academic interests and completion rates. Specific…

  1. The Determination of Earth Orientation by VLBI and GNSS: Principles and Results

    NASA Astrophysics Data System (ADS)

    Capitaine, Nicole

    2017-10-01

    The Earth Orientation Parameters (EOP) connect the International Terrestrial Reference System (ITRS) to the Geocentric Celestial Reference System (GCRS). These parameters, i.e., Universal Time, UT1, and pole coordinates in the ITRS and in the GCRS, describe the irregularities of the Earth's rotation. They are mainly determined by two modern astro-geodetic techniques, VLBI (Very Long Baseline Radio Interferometry) on extragalactic radio sources, which is used to realize and maintain the International Celestial Reference System (ICRS), and Global Navigation Satellite System (GNSS), especially GPS (Global Positioning System), which has an important contribution to the realization of the ITRS. The aim of this presentation is twofold: to present the modern bases for the consider- ation of Earth orientation and to discuss how the principles of VLBI and GPS give access to the measure of different components of the EOP variations, especially UT1. The accuracy that can be achieved is based on the improved concepts, definitions, and models that have been adopted by IAU/IUGG resolutions on reference systems and Earth's rotation, as well as on the refined strategy of the observations.

  2. Combinación de Valores de Longitud del Día (LOD) según ventanas de frecuencia

    NASA Astrophysics Data System (ADS)

    Fernández, L. I.; Arias, E. F.; Gambis, D.

    El concepto de solución combinada se sustenta en el hecho de que las diferentes series temporales de datos derivadas a partir de distintas técnicas de la Geodesia Espacial son muy disimiles entre si. Las principales diferencias, fácilmente detectables, entre las distintas series son: diferente intervalo de muestreo, extensión temporal y calidad. Los datos cubren un período reciente de 27 meses (julio 96-oct. 98). Se utilizaron estimaciones de la longitud del día (LOD) originadas en 10 centros operativos del IERS (International Earth Rotation Service) a partir de las técnicas GPS (Global Positioning System) y SLR (Satellite Laser Ranging). La serie temporal combinada así obtenida se comparó con la solución EOP (Parámetros de la Orientación Terrestre) combinada multi-técnica derivada por el IERS (C04). El comportamiento del ruido en LOD para todas las técnicas mostró ser dependiente de la frecuencia (Vondrak, 1998). Por esto, las series dato se dividieron en ventanas de frecuencia, luego de haberles removido bies y tendencias. Luego, se asignaron diferentes factores de peso a cada ventana discriminando por técnicas. Finalmente estas soluciones parcialmente combinadas se mezclaron para obtener la solución combinada final. Sabemos que la mejor solución combinada tendrá una precisión menor que la precisión de las series temporales de datos que la originaron. Aun así, la importancia de una serie combinada confiable de EOP, esto es, de una precisión aceptable y libre de sistematismos evidentes, radica en la necesidad de una base de datos EOP de referencia para el estudio de fenómenos geofísicos que motivan variaciones en la rotación terrestre.

  3. A Study of Educational Opportunity Program (EOP) Students Within Health Science Career Preparation Programs.

    ERIC Educational Resources Information Center

    James, William H.; And Others

    Participation of minority students within health science career preparation programs is investigated in this study from the University of Washington. The history of minority admissions to medical and nursing schools throughout the country is reviewed. Health sciences programs for minorities at the university are discussed and the impact of the…

  4. Language Learning Strategies of English for Specific Purposes Students at a Public University in Malaysia

    ERIC Educational Resources Information Center

    Shah, Mohamed Ismail Ahamad; Ismail, Yusof; Esa, Zaleha; Muhamad, Ainon Jariah

    2013-01-01

    Studies on strategy research have shown the usefulness and importance of language learning strategies (LLS) for ESL and EFL learners. However, research on content-based learners in relation to English for Academic Purposes (EAP) and English for Occupational Purposes (EOP) has yet to be undertaken. This study, therefore, investigated the learning…

  5. VLBI-based Products - Naval Oceanography Portal

    Science.gov Websites

    section Advanced Search... Sections Home Time Earth Orientation Astronomy Meteorology Oceanography Ice You are here: Home › USNO › Earth Orientation › VLBI-based Products USNO Logo USNO Navigation Earth determine Earth Orientation Parameters (EOP) is Very Long Baseline Interferometry (VLBI). USNO provides both

  6. OBE EAP-EOP Model: A Proposed Instructional Design in English for Specific Purposes

    ERIC Educational Resources Information Center

    Hernandez, Hjalmar Punla

    2016-01-01

    Outcome-Based Education (OBE) demands innovative Instructional Designs (ID) in the 21st century. Being a descriptive-qualitative research, this paper aimed to (1) identify the ID used in the English language curricula of a private tertiary level institution in the Southern Luzon, Philippines, (2) determined the elements that the ID of the English…

  7. Going Back to School: An Interview with Mike Rose

    ERIC Educational Resources Information Center

    Adams, Peter

    2017-01-01

    Mike Rose is a professor in the UCLA Graduate School of Education and Information Studies. He has taught in a wide range of educational settings - from elementary school to adult literacy and job training programs--and has directed an Educational Opportunity (EOP) tutorial center. He is an author and member of the National Academy of Education and…

  8. 78 FR 26782 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ...: Administration for Community Living, HHS. ACTION: Notice. SUMMARY: The Administration for Community Living (ACL....eop.gov , Attn: OMB Desk Officer for ACL. FOR FURTHER INFORMATION CONTACT: Elena Fazio at 202-357-3583 or email: [email protected]acl.hhs.gov . SUPPLEMENTARY INFORMATION: In compliance with 44 U.S.C. 3507, ACL...

  9. Study of the 1978 Summer STEP. The Summer "Bridge" Program at the Learning Skills Center, University of California, Davis.

    ERIC Educational Resources Information Center

    Suhr, Jeanne

    The summer "bridge" part of the Special Transitional Enrichment Program (STEP) at the University of California (UC), Davis, was evaluated with attention to first-year academic performance and retention. STEP, part of the Educational Opportunity Program (EOP), is an orientation and academic program to help low-income and minority students…

  10. HOPX1 Ea (Eop3) in Erwinia Amylovora functions as an avirulence gene in apple and is regulated by HRPL

    USDA-ARS?s Scientific Manuscript database

    Fire blight is a devastating disease of rosaceous plants caused by the Gram-negative bacterium E. amylovora. This pathogen delivers virulence proteins into host cells utilizing the Type-Three Secretion System (T3SS). Expression of the T3SS and associated substrates are activated by the alternative s...

  11. The Experiences of Low-Income Latino/a Students in the California Community College System at a Time of Education Budget Cuts

    ERIC Educational Resources Information Center

    Chacon, Justin Akers

    2013-01-01

    Budget cuts have reduced courses and student services within California community colleges. This coincides with the growth of low-income Latino male (Latinos) and Latina female (Latinas) student enrollment. Budget cuts have been implemented throughout the system, including in the Extended Opportunity Programs and Services (EOPS), which…

  12. ERP Estimation using a Kalman Filter in VLBI

    NASA Astrophysics Data System (ADS)

    Karbon, M.; Soja, B.; Nilsson, T.; Heinkelmann, R.; Liu, L.; Lu, C.; Mora-Diaz, J. A.; Raposo-Pulido, V.; Xu, M.; Schuh, H.

    2014-12-01

    Geodetic Very Long Baseline Interferometry (VLBI) is one of the primary space geodetic techniques, providing the full set of Earth Orientation Parameters (EOP), and it is unique for observing long term Universal Time (UT1). For applications such as satellite-based navigation and positioning, accurate and continuous ERP obtained in near real-time are essential. They also allow the precise tracking of interplanetary spacecraft. One of the goals of VGOS (VLBI Global Observing System) is to provide such near real-time ERP. With the launch of this next generation VLBI system, the International VLBI Service for Geodesy and Astrometry (IVS) increased its efforts not only to reach 1 mm accuracy on a global scale but also to reduce the time span between the collection of VLBI observations and the availability of the final results substantially. Project VLBI-ART contributes to these objectives by implementing an elaborate Kalman filter, which represents a perfect tool for analyzing VLBI data in quasi real-time. The goal is to implement it in the GFZ version of the Vienna VLBI Software (VieVS) as a completely automated tool, i.e., with no need for human interaction. Here we present the methodology and first results of Kalman filtered EOP from VLBI data.

  13. Estimating the Earth's geometry, rotation and gravity field using a multi-satellite SLR solution

    NASA Astrophysics Data System (ADS)

    Stefka, V.; Blossfeld, M.; Mueller, H.; Gerstl, M.; Panafidina, N.

    2012-12-01

    Satellite Laser Ranging (SLR) is the unique technique to determine station coordinates, Earth Orientation Parameter (EOP) and Stokes coefficients of the Earth's gravity field in one common adjustment. These parameters form the so called "three pillars" (Plag & Pearlman, 2009) of the Global Geodetic Observing System (GGOS). In its function as official analysis center of the International Laser Ranging Service (ILRS), DGFI is developing and maintaining software to process SLR observations called "DGFI Orbit and Geodetic parameter estimation Software" (DOGS). The software is used to analyze SLR observations and to compute multi-satellite solutions. To take benefit of different orbit performances (e.g. inclination and altitude), a solution using ten different spherical satellites (ETALON1/2, LAGEOS1/2, STELLA, STARLETTE, AJISAI, LARETS, LARES, BLITS) covering the period of 12 years of observations is computed. The satellites are relatively weighted using a variance component estimation (VCE). The obtained weights are analyzed w.r.t. the potential of the satellite to monitor changes in the Earths geometry, rotation and gravity field. The estimated parameters (station coordinates and EOP) are validated w.r.t. official time series of the IERS. The Stokes coefficients are compared to recent gravity field solutions.

  14. Estimating the Earth's gravity field using a multi-satellite SLR solution

    NASA Astrophysics Data System (ADS)

    Bloßfeld, Mathis; Stefka, Vojtech; Müller, Horst; Gerstl, Michael

    2013-04-01

    Satellite Laser Ranging (SLR) is the unique technique to determine station coordinates, Earth Orientation Parameter (EOP) and Stokes coefficients of the Earth's gravity field in one common adjustment. These parameters form the so called "three pillars" (Plag & Pearlman, 2009) of the Global Geodetic Observing System (GGOS). In its function as official analysis center of the International Laser Ranging Service (ILRS), DGFI is developing and maintaining software to process SLR observations called "DGFI Orbit and Geodetic parameter estimation Software" (DOGS). The software is used to analyze SLR observations and to compute multi-satellite solutions. To take benefit of different orbit performances (e.g. inclination and altitude), a solution using ten different spherical satellites (ETALON1/2, LAGEOS1/2, STELLA, STARLETTE, AJISAI, LARETS, LARES, BLITS) covering 12 years of observations is computed. The satellites are relatively weighted using a variance component estimation (VCE). The obtained weights are analyzed w.r.t. the potential of the satellite to monitor changes in the Earths geometry, rotation and gravity field. The estimated parameters (station coordinates and EOP) are validated w.r.t. official time series of the IERS. The obtained Stokes coefficients are compared to recent gravity field solutions and discussed in detail.

  15. 75 FR 38523 - Notice of Public Information Collection(s) Being Submitted for Review and Approval to the Office...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... small business concerns with fewer than 25 employees. The FCC may not conduct or sponsor a collection of... advise the FCC contact listed below as soon as possible. ADDRESSES: Direct all PRA comments to Nicholas A....eop.gov and to the Federal Communications Commission via email to [email protected]fcc.gov and [email protected]fcc...

  16. The Effectiveness of an Undecided Decision-Making, Goal-Setting Workshop on the Academic Success of College Students Who Have Not Declared a Major

    ERIC Educational Resources Information Center

    Mushegyan, Anaid

    2010-01-01

    The problem: The purpose of this study was to determine the efficacy of an Undecided Decision-Making, Goal-Setting Workshop through an examination of changes in grade point averages (GPAs) among participating community college students. The method: To investigate this problem, 98 EOPS undecided students were asked to attend an Undecided…

  17. English for Specific Purposes: The State of the Art (An Online Interview with Ann M. Johns)

    ERIC Educational Resources Information Center

    Johns, Ann M.; Salmani Nodoushan, M. A.

    2015-01-01

    This forum paper is based on a friendly and informative interview conducted with Professor Ann M. Johns. In providing answers to the interview questions, Professor Johns suggests that all good teaching is ESP, and also distinguishes between EOP and ESP in that the former entails much more "just in time" learning while the latter may be…

  18. Is This Your Year to Inspire a Child? | Poster

    Cancer.gov

    By Julie Hartman, Guest Writer The Elementary Outreach Program (EOP) is looking for volunteers for the 2013–2014 school year. This program is designed to bring science into the classrooms of Frederick County students in grades 1 through 5. You’ll have a chance to work with small groups of children, presenting hands-on lessons that are coordinated with the school curriculum.

  19. [Contribution of hemodynamic disturbances in magistral vessels to optic neuropathy progression and ocular tension changes in endocrine ophthalmopathy].

    PubMed

    Likhvantseva, V G; Kharlap, S I; Korosteleva, E V; Solomatina, M V; Mel'nikova, M V; Budanova, S V; Regeb, A Ben; Vygodin, V A

    2015-01-01

    to investigate the contribution of various hemodynamic disturbances in magistral vessels to optic neuropathy (ON) progression and ocular tension changes in endocrine ophthalmopathy (EOP). A total of 39 patients (78 eyes) with subclinical EOP (clinical activity score, CAS ≤ 2) associated with Graves' disease (n = 32, 64 eyes) or autoimmune thyroiditis (n = 7, 14 eyes) were examined. Orbit echography was performed in all patients. Blood flow was assessed with a Voluson 730 PRO ultrasound diagnostic system ("Kretz", Austria) in triplex mode (B-scan, color Doppler flow mapping in combination with pulse-wave Doppler). Thus obtained hemodynamic parameters in ophthalmic artery, central retinal artery (CRA), central retinal vein (CRV), short posterior ciliary arteries (SPCA), and long posterior ciliary arteries (LPCA) were analyzed. To reveal the role of hemodynamic disturbances in the above mentioned vessels in ON progression and eye pressure maintenance, the patients were divided into 7 groups. Only those eyes, whose peripheral indices were increased by more than 25% of normal values and diastolic blood flow decreased by not less than 25%, were selected for further study. Intraocular pressure changes were evaluated by group mean (Mmean = M ± m mmHg), optic neuropathy progression--by the difference in group mean depth (dB) and number of scotomas between the first and the last visit (6 months of observation). In almost all types of perfusion disturbances, the resultant chronic ocular ischemia causes a decrease in IOP. The only exception, as shown, is simultaneous involvement of CRA, SPCA, and LPCA. The level of blood flow disturbance determines the severity of qualitative and quantitative changes in eyes with EOP-associated ON. The rate of ON progression directly correlates with baseline IOP values on day zero. Long-lasting chronic impairment of blood supply of the eyeball leads to reduction in ocular tension and progression of optic neuropathy. Combined perfusion disturbances in CRA and LPCA as well as in CRA, LPCA, and SPCA can be considered a high-risk factor, while SPCA and/or LPCA involvement--a moderate-risk factor.

  20. Tuning metal-to-metal charge transfer of mixed-valence complexes containing ferrocenylpyridine and rutheniumammines via solvent donicity and substituent effects.

    PubMed

    Chen, Y J; Kao, C H; Lin, S J; Tai, C C; Kwan, K S

    2000-01-24

    A homogeneous series of heterobimetallic complexes of [R-Fc(4-py)Ru(NH3)5](PF6)2 (R = H, Et, Br, acetyl; Fc(4-py) = 4-ferrocenylpyridine) have been prepared and characterized. The mixed-valence species generated in situ using ferrocenium hexafluorophosphate as the oxidant show class II behavior, and the oxidized sites are ruthenium centered. deltaE(1/2), E(1/2)(Fe(III)/Fe(II)) - E(1/2)(Ru(III)/Ru(II)), an upper limit for deltaGo that is an energetic difference between the donor and acceptor sites, changes sharply and linearly with Gutmann solvent donor number (DN) and Hammett substituent constants (sigma). The solvent-dependent and substituent-dependent intervalence transfer bands were found to vary almost exclusively with deltaE(1/2). The activation energy for the optical electron transfer versus deltaE(1/2) plot yields a common nuclear reorganization energy (lambda) of 0.74 +/- 0.04 eV for this series. The equation that allows one to incorporate the effect of both solvent donicity and substituents on optical electron transfer is Eop = lambda + deltaGo, where deltaGo = (deltaGo)intrinsic + (deltaGo)solvent donicity + (deltaGo)substituent effect (deltaGo )intinnsic with a numerical value of 0.083 +/- 0.045 eV was obtained from the intercept of the deltaE(1/2) of [H-Fc(4-py)Ru(NH3)5]2+,3+,4+ versus DN plot. (deltaGo)solvent donicity was obtained from the average slopes of the deltaE(1/2) of [R-Fc-(4-py)Ru(NH3)5]2+,3+,4+ versus DN plot, and (deltaGo)substituent effect was obtained from the average slopes of the corresponding deltaE(1/2) versus sigma plot. The empirical equation allows one to finely tune Eop of this series to Eop = 0.82 + 0.019(DN) + 0.44sigma eV at 298 K, and the discrepancy between the calculated and experimental data is less than 6%.

  1. Parametric symmetries in exactly solvable real and PT symmetric complex potentials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yadav, Rajesh Kumar, E-mail: rajeshastrophysics@gmail.com; Khare, Avinash, E-mail: khare@physics.unipune.ac.in; Bagchi, Bijan, E-mail: bbagchi123@gmail.com

    In this paper, we discuss the parametric symmetries in different exactly solvable systems characterized by real or complex PT symmetric potentials. We focus our attention on the conventional potentials such as the generalized Pöschl Teller (GPT), Scarf-I, and PT symmetric Scarf-II which are invariant under certain parametric transformations. The resulting set of potentials is shown to yield a completely different behavior of the bound state solutions. Further, the supersymmetric partner potentials acquire different forms under such parametric transformations leading to new sets of exactly solvable real and PT symmetric complex potentials. These potentials are also observed to be shape invariantmore » (SI) in nature. We subsequently take up a study of the newly discovered rationally extended SI potentials, corresponding to the above mentioned conventional potentials, whose bound state solutions are associated with the exceptional orthogonal polynomials (EOPs). We discuss the transformations of the corresponding Casimir operator employing the properties of the so(2, 1) algebra.« less

  2. Laboratory Testing of Electro-Osmotic Pulse Technology to Reduce and Maintain Low Moisture Content in Concrete

    DTIC Science & Technology

    2009-02-01

    technology minimizes harmful effects to concrete and rebar and prevents over drying, pore blocking and electrode polarization. Principles of EOP...LABORATORY TESTING OF ELECTRO-OSMOTIC PULSE TECHNOLOGY TO REDUCE AND MAINTAIN LOW MOISTURE CONTENT IN CONCRETE Orange S. Marshall, Vincent F...Laboratory 2009 Army Corrosion Summit Clearwater Beach, FL 6 January 2009 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting

  3. Inoculation of Malus genotypes with a set of Erwinia amylovora strains indicates a gene-for-gene relationship between the effector gene eop1 and both Malus floribunda 821 and Malus 'Evereste'

    USDA-ARS?s Scientific Manuscript database

    The Gram-negative bacterium Erwinia amylovora (Burrill) Winslow. et al., causal agent of fire blight disease in pome fruit trees, encodes a type three secretion system (T3SS) that functions to translocate effector proteins into plant cells that collectively function to suppress host defenses and ena...

  4. Development of a real-world direct interface for integrated DNA extraction and amplification in a microfluidic device.

    PubMed

    Shaw, Kirsty J; Joyce, Domino A; Docker, Peter T; Dyer, Charlotte E; Greenway, Gillian M; Greenman, John; Haswell, Stephen J

    2011-02-07

    Integrated DNA extraction and amplification have been carried out in a microfluidic device using electro-osmotic pumping (EOP) for fluidic control. All the necessary reagents for performing both DNA extraction and polymerase chain reaction (PCR) amplification were pre-loaded into the microfluidic device following encapsulation in agarose gel. Buccal cells were collected using OmniSwabs [Whatman™, UK] and manually added to a chaotropic binding/lysis solution pre-loaded into the microfluidic device. The released DNA was then adsorbed onto a silica monolith contained within the DNA extraction chamber and the microfluidic device sealed using polymer electrodes. The washing and elution steps for DNA extraction were carried out using EOP, resulting in transfer of the eluted DNA into the PCR chamber. Thermal cycling, achieved using a Peltier element, resulted in amplification of the Amelogenin locus as confirmed using conventional capillary gel electrophoresis. It was demonstrated that the PCR reagents could be stored in the microfluidic device for at least 8 weeks at 4 °C with no significant loss of activity. Such methodology lends itself to the production of 'ready-to-use' microfluidic devices containing all the necessary reagents for sample processing, with many obvious applications in forensics and clinical medicine.

  5. Results of monitoring of the high orbits with ISON optical network

    NASA Astrophysics Data System (ADS)

    Molotov, Igor; Schildknecht, Thomas; Zalles, Rodolfo; Rumyantsev, Vasilij; Voropaev, Viktor; Zolotov, Vladimir; Kokina, Tatiana; Montojo, Francisco Javier; Namkhai, Tungalag

    2016-07-01

    International Scientific Optical Network (ISON) represents one of largest systems specializing in observation of space objects. ISON provides permanent monitoring of the whole GEO region, regular surveying of Molniya type orbits, and tracking of objects at GEO, GTO, HEO and LEO. ISON project is continuously developing and is joining now the 37 observation facilities in 15 countries with 79 telescopes of different class (aperture from 12.5 cm to 2.6 m). 15.4 millions measurements in 2.1 millions of tracklets for about 4100 objects are collected by KIAM in 2015. 339 new space objects have been discovered, 307 previously lost objects have been rediscovered. Telescopes of two European observatories (AIUB Zimmerwald and TFRM Barcelona) and two Latin American observatories (Bolivian Tarija and Mexican UAS Cosala) have joined to the ISON survey subsystem. New subsystem of 7 telescopes for extended GEO surveys is created (it allows KIAM to determine more precise GEO orbits for conjunction analysis). Also deployment of Roscosmos subsystem of six dedicated mini-observatories EOP-1/EOP-2 has been completed. ISON encompasses five groups of telescopes and three scheduling centers to better serve user's requests. Obtained measurements are processing at KIAM ballistic center to be used for scientific and applied goals, including collision risks analysis and space situation analysis. Achieved parameters of the above mentioned telescopes and plans of ISON network development will be presented and discussed.

  6. Navigation Architecture For A Space Mobile Network

    NASA Technical Reports Server (NTRS)

    Valdez, Jennifer E.; Ashman, Benjamin; Gramling, Cheryl; Heckler, Gregory W.; Carpenter, Russell

    2016-01-01

    The Tracking and Data Relay Satellite System (TDRSS) Augmentation Service for Satellites (TASS) is a proposed beacon service to provide a global, space-based GPS augmentation service based on the NASA Global Differential GPS (GDGPS) System. The TASS signal will be tied to the GPS time system and usable as an additional ranging and Doppler radiometric source. Additionally, it will provide data vital to autonomous navigation in the near Earth regime, including space weather information, TDRS ephemerides, Earth Orientation Parameters (EOP), and forward commanding capability. TASS benefits include enhancing situational awareness, enabling increased autonomy, and providing near real-time command access for user platforms. As NASA Headquarters Space Communication and Navigation Office (SCaN) begins to move away from a centralized network architecture and towards a Space Mobile Network (SMN) that allows for user initiated services, autonomous navigation will be a key part of such a system. This paper explores how a TASS beacon service enables the Space Mobile Networking paradigm, what a typical user platform would require, and provides an in-depth analysis of several navigation scenarios and operations concepts.

  7. An Overview of Major Terrestrial, Celestial, and Temporal Coordinate Systems for Target Tracking

    DTIC Science & Technology

    2016-08-10

    interp and Subroutines) http://hpiers.obspm.fr/eop-pc/index.php?index=models General Software for Astronomy and Time Conversions The IAU’s Standards...of Fundamental Astronomy Software [146] http://www.iausofa.org Software for Optimal 2D Assignment An overview of 2D assignment algorithms; the... Astronomy (SOFA) library were used to change the epoch of the data. The points in red are at the epoch of the Hipparcos catalog (1994.25 TT), and 20

  8. The Complexity of Parallel Algorithms,

    DTIC Science & Technology

    1985-11-01

    programns have been written for se(luiential coiipn ters. Many p~eop~le want coimp ~ilers dihal. will c(nimpile t he, code for parallel machines, to avoid...between two vertices. We also rely on parallel algorithms for maintaining data structures and manipulating graphs. We do not go into the details of these...Jpatlis and maintain connected coimp ~onents. The routine is: - 35 .- ExtendPath(r, Q, V) begin P +-0; s 4- while there is a path in V - P from s to a vertex

  9. Current Trends in Satellite Laser Ranging

    NASA Technical Reports Server (NTRS)

    Pearlman, M. R.; Appleby, G. M.; Kirchner, G.; McGarry, J.; Murphy, T.; Noll, C. E.; Pavlis, E. C.; Pierron, F.

    2010-01-01

    Satellite Laser Ranging (SLR) techniques are used to accurately measure the distance from ground stations to retroreflectors on satellites and the moon. SLR is one of the fundamental techniques that define the international Terrestrial Reference Frame (iTRF), which is the basis upon which we measure many aspects of global change over space, time, and evolving technology. It is one of the fundamental techniques that define at a level of precision of a few mm the origin and scale of the ITRF. Laser Ranging provides precision orbit determination and instrument calibration/validation for satellite-borne altimeters for the better understanding of sea level change, ocean dynamics, ice budget, and terrestrial topography. Laser ranging is also a tool to study the dynamics of the Moon and fundamental constants. Many of the GNSS satellites now carry retro-reflectors for improved orbit determination, harmonization of reference frames, and in-orbit co-location and system performance validation. The GNSS Constellations will be the means of making the reference frame available to worldwide users. Data and products from these measurements support key aspects of the GEOSS 10-Year implementation Plan adopted on February 16, 2005, The ITRF has been identified as a key contribution of the JAG to GEOSS and the ILRS makes a major contribution for its development since its foundation. The ILRS delivers weekly additional realizations that are accumulated sequentially to extend the ITRF and the Earth Orientation Parameter (EOP) series with a daily resolution. Additional products are currently under development such as precise orbits of satellites, EOP with daily availability, low-degree gravitational harmonics for studies of Earth dynamics and kinematics, etc. SLR technology continues to evolve toward the next generation laser ranging systems as programmatic requirements become more stringent. Ranging accuracy is improving as higher repetition rate, narrower pulse lasers and faster detectors are implemented. Automation and pass interleaving at some stations is already expanding temporal coverage. Web-based safety keys are allowing the SLR network stations to range to optically vulnerable satellites. Some stations are experimenting with two-wavelength operation as a means of better understanding the atmospheric refraction and with very low power laser to improve eye-safety conditions. New retroreflector designs are improving the signal link and enable daylight ranging. Dramatic improvements have also been made with lunar ranging with the new APOLLO Site in New ?Mexico, USA and the upgraded lunar station "MEO" in Grasse,

  10. Connecting kinematic and dynamic reference frames by D-VLBI

    NASA Astrophysics Data System (ADS)

    Schuh, Harald; Plank, Lucia; Madzak, Matthias; Böhm, Johannes

    2012-08-01

    In geodetic and astrometric practice, terrestrial station coordinates are usually provided in the kinematic International Terrestrial Reference Frame (ITRF) and radio source coordinates in the International Celestial Reference Frame (ICRF), whereas measurements of space probes such as satellites and spacecrafts, or planetary ephemerides rest upon dynamical theories. To avoid inconsistencies and errors during measurement and calculation procedures, exact frame ties between quasi - inertial, kinematic and dynamic reference frames have to be secured. While the Earth Orientation Parameters (EOP), e.g. measured by VLBI, link the ITRF to the ICRF, the ties with the dynamic frames can be established with the differential Very Long Baseline Interferometry (D - VLBI) method. By observing space probes alternately t o radio sources, the relative position of the targets to each other on the sky can be determined with high accuracy. While D - VLBI is a common technique in astrophysics (source imaging) and deep space navigation, just recently there have been several effort s to use it for geodetic purposes. We present investigations concerning possible VLBI observations to satellites. This includes the potential usage of available GNNS satellites as well as specifically designed missions, as e.g. the GRASP mission proposed b y JPL/NASA and an international consortium, where the aspect of co - location in space of various techniques (VLBI, SLR, GNSS, DORIS) is the main focus.

  11. Monitoring of emerging pollutants in Guadiamar River basin (South of Spain): analytical method, spatial distribution and environmental risk assessment.

    PubMed

    Garrido, Eva; Camacho-Muñoz, Dolores; Martín, Julia; Santos, Antonio; Santos, Juan Luis; Aparicio, Irene; Alonso, Esteban

    2016-12-01

    Guadiamar River is located in the southwest of the Iberian Peninsula and connects two protected areas in the South of Spain: Sierra Morena and Doñana National Park. It is sited in an area affected by urban, industrial and agriculture sewage pollution and with tradition on intensive mining activities. Most of the studies performed in this area have been mainly focused on the presence of heavy metals and, until now, little is known about the occurrence of other contaminants such as emerging organic pollutants (EOPs). In this work, an analytical method has been optimized and validated for monitoring of forty-seven EOPs in surface water. The analytical method has been applied to study the distribution and environmental risk of these pollutants in Guadiamar River basin. The analytical method was based on solid-phase extraction and determination by liquid chromatography-triple quadrupole-tandem mass spectrometry. The 60 % of the target compounds were found in the analyzed samples. The highest concentrations were found for two plasticizers (bisphenol A and di(2-ethyhexyl)phthalate, mean concentration up to 930 ng/L) and two pharmaceutical compounds (caffeine (up to 623 ng/L) and salicylic acid (up to 318 ng/L)). This study allowed to evaluate the potential sources (industrial or urban) of the studied compounds and the spatial distribution of their concentrations along the river. Environmental risk assessment showed a major risk on the south of the river, mainly due to discharges of wastewater effluents.

  12. Long-term Bond Strength between Layering Indirect Composite Material and Zirconia Coated with Silicabased Ceramics.

    PubMed

    Fushiki, Ryosuke; Komine, Futoshi; Honda, Junichi; Kamio, Shingo; Blatz, Markus B; Matsumura, Hideo

    2015-06-01

    This study evaluated the long-term shear bond strength between an indirect composite material and a zirconia framework coated with silica-based ceramics, taking the effect of different primers into account. A total of 165 airborne-particle abraded zirconia disks were subjected to one of three pretreatments: no pretreatment (ZR-AB), airborne-particle abrasion of zirconia coated with feldspathic porcelain (ZR-PO-AB), and 9.5% hydrofluoric acid etching of zirconia coated with feldspathic porcelain (ZR-PO-HF). An indirect composite material (Estenia C&B) was then bonded to the zirconia disks after they were treated with one of the following primers: Clearfil Photo Bond (CPB), Clearfil Photo Bond with Clearfil Porcelain Bond Activator (CPB + Activator), Estenia Opaque Primer (EOP), Porcelain Liner M Liquid B (PLB), or no priming (CON, control group). Shear bond strength was tested after 100,000 thermocycles, and the data were analyzed using the Steel-Dwass U-test (α = 0.05). For ZR-PO-AB and ZR-PO-HF specimens, bond strength was highest in the CPB+Activator group (25.8 MPa and 22.4 MPa, respectively). Bond strengths were significantly lower for ZR-AB specimens in the CON and PLB groups and for ZR-PO-AB specimens in the CON, CPB, and EOP groups. Combined application of a hydrophobic phosphate monomer (MDP) and silane coupling agent enhanced the long-term bond strength of indirect composite material to a zirconia coated with silica-based ceramics.

  13. OS087. Maternal characteristics, mean arterial pressure and PLGF in early prediction of preeclampsia.

    PubMed

    Kuc, S; Koster, M P; Franx, A; Schielen, P C; Visser, G H

    2012-07-01

    In a previous study, we described the predictive value of first-trimester pregnancy-associated plasma protein-A (PAPP-A), free beta-subunit of human chorionic gonadotrophin (fb-hCG), Placental Growth Factor (PlGF) and A Desintegrin And Metalloproteinase 12 (ADAM12) for early onset preeclampsia (delivery <34 weeks) [1]. The objective of the current study was to obtain the predictive value of these serum makers, for both early onset PE (EOPE) and late onset PE (LOPE), combined with maternal characteristics and first-trimester maternal mean arterial blood pressure (MAP). This was a nested case-control study, using stored first-trimester maternal serum from 167 women who subsequently developed PE, and 500 uncomplicated singleton pregnancies which resulted in a live birth =>37 weeks. Maternal characteristics (i.e. medical records, parity, weight, length) MAP and pregnancy outcome (i.e. gestational age at delivery, birthweight, fetal sex) were collected for each individual and used to calculate prior risks for PE in a multiple logistic regression model. MAP values and marker levels of PAPP-A, fb-hCG, PlGF and ADAM12 were expressed as multiples of the gestation-specific normal median (MoMs). Subsequently, MoMs were log-transformed and compared between PE and controls using Student's t-tests. Posterior risks were calculated using different combinations of variables;(1) maternal characteristics, serum markers, and MAP separately (2) maternal characteristics combined with serum markers or MAP (3) maternal characteristics combined with serum markers and MAP. The model-predicted detection rates (DR) for fixed 10% false-positive rates were obtained for EOPE and LOPE with or without intra-uterine growth restriction (IUGR,birth weight <10th centile). The maternal characteristics: maternal age, weight, length, smoking status and nulliparity were discriminative between PE and control groups and therefore incorporated in the multiple logistic regression model. MoM MAP was significantly elevated (1.10 p<0.001; 1.07 p<0.001) and MoM PlGF was significantly reduced (0.95 p=0.016; 0.90 p=0.029) in the EOPE and LOPE group, respectively. The differences in markers for IUGR groups were larger. The estimated DRs of the three different models are presented in the table. This study demonstrates that first-trimester MAP and PlGF combined with maternal characteristics are promising markers in risk assessment for PE. Combination of markers proved especially useful for risk assessment for term PE. Detection rates were higher in the presence of IUGR. Copyright © 2012. Published by Elsevier B.V.

  14. Simple practical approach for sample loading prior to DNA extraction using a silica monolith in a microfluidic device.

    PubMed

    Shaw, Kirsty J; Joyce, Domino A; Docker, Peter T; Dyer, Charlotte E; Greenman, John; Greenway, Gillian M; Haswell, Stephen J

    2009-12-07

    A novel DNA loading methodology is presented for performing DNA extraction on a microfluidic system. DNA in a chaotropic salt solution was manually loaded onto a silica monolith orthogonal to the subsequent flow of wash and elution solutions. DNA was successfully extracted from buccal swabs using electro-osmotic pumping (EOP) coupled with in situ reagents contained within a 1.5% agarose gel matrix. The extracted DNA was of sufficient quantity and purity for polymerase chain reaction (PCR) amplification.

  15. Sterling Software: An NLToolset-based System for MUC-6

    DTIC Science & Technology

    1995-11-01

    COCA - COLA ADVERTISING *PERIOD* ) ("’OOUBLEQUOTE"’ *EO-P"’ *SO-P"’ "’CAP* ABBREV _MR *CAP...34 Coca - Cola ". Since we weren’t using the parser, the part-of- speech obtained by a lexical lookup was of interest mainly if it was something like city-name...any contextual clues (such as "White House", "Fannie Mae", "Big Board", " Coca - cola " and "Coke", "Macy’s", "Exxon", etc). 252 SUB 6 0 0

  16. IVS: Current Status and Future Plans

    NASA Astrophysics Data System (ADS)

    Behrend, D.; Nothnagel, A.; Petrachenko, W. T.; Tuccari, G.

    2016-12-01

    The International VLBI Service for Geodesy and Astrometry (IVS) is a globally operating service that coordinates and performs Very Long Baseline Interferometry (VLBI) activities through its constituent components. The VLBI activities are associated with the creation, provision, dissemination, and archiving of relevant VLBI data and products. The products mostly pertain to the determination of the celestial and terrestrial reference frames, the Earth orientation parameters (EOP), atmospheric parameters as well as other ancillary parameters. The IVS observational network currently consists of about 40 radio telescopes worldwide. Subsets of these telescopes (8-12 stations) participate in 24-hour observing sessions that are run several times per week and in 1-hour intensive sessions for UT1 determination every day. The current VLBI network was developed mainly in the 1970s and 1980s. A number of factors, including aging infrastructure and demanding new scientific requirements, started to challenge its future sustainability and relevance. In response, the IVS and other groups developed and started implementing the next generation VLBI system, called VGOS (VLBI Global Observing System), at existing and new sites. The VGOS network is expected to reach maturity in the early 2020s. We describe the current status, progress, and anticipated prospects of geodetic/astrometric VLBI and the IVS.

  17. An Improved Empirical Harmonic Model of the Celestial Intermediate Pole Offsets from a Global VLBI Solution

    NASA Astrophysics Data System (ADS)

    Belda, Santiago; Heinkelmann, Robert; Ferrándiz, José M.; Karbon, Maria; Nilsson, Tobias; Schuh, Harald

    2017-10-01

    Very Long Baseline Interferometry (VLBI) is the only space geodetic technique capable of measuring all the Earth orientation parameters (EOP) accurately and simultaneously. Modeling the Earth's rotational motion in space within the stringent consistency goals of the Global Geodetic Observing System (GGOS) makes VLBI observations essential for constraining the rotation theories. However, the inaccuracy of early VLBI data and the outdated products could cause non-compliance with these goals. In this paper, we perform a global VLBI analysis of sessions with different processing settings to determine a new set of empirical corrections to the precession offsets and rates, and to the amplitudes of a wide set of terms included in the IAU 2006/2000A precession-nutation theory. We discuss the results in terms of consistency, systematic errors, and physics of the Earth. We find that the largest improvements w.r.t. the values from IAU 2006/2000A precession-nutation theory are associated with the longest periods (e.g., 18.6-yr nutation). A statistical analysis of the residuals shows that the provided corrections attain an error reduction at the level of 15 μas. Additionally, including a Free Core Nutation (FCN) model into a priori Celestial Pole Offsets (CPOs) provides the lowest Weighted Root Mean Square (WRMS) of residuals. We show that the CPO estimates are quite insensitive to TRF choice, but slightly sensitive to the a priori EOP and the inclusion of different VLBI sessions. Finally, the remaining residuals reveal two apparent retrograde signals with periods of nearly 2069 and 1034 days.

  18. The C lostridium difficile cell wall protein CwpV confers phase‐variable phage resistance

    PubMed Central

    Sekulovic, Ognjen; Ospina Bedoya, Maicol; Fivian‐Hughes, Amanda S.; Fairweather, Neil F.

    2015-01-01

    Summary Bacteriophages are present in virtually all ecosystems, and bacteria have developed multiple antiphage strategies to counter their attacks. C lostridium difficile is an important pathogen causing severe intestinal infections in humans and animals. Here we show that the conserved cell‐surface protein CwpV provides antiphage protection in C . difficile. This protein, for which the expression is phase‐variable, is classified into five types, each differing in their repeat‐containing C‐terminal domain. When expressed constitutively from a plasmid or the chromosome of locked ‘ON’ cells of C . difficile  R20291, CwpV conferred antiphage protection. Differences in the level of phage protection were observed depending on the phage morphological group, siphophages being the most sensitive with efficiency of plaquing (EOP) values of < 5 × 10−7 for phages ϕCD38‐2, ϕCD111 and ϕCD146. Protection against the myophages ϕMMP01 and ϕCD52 was weaker, with EOP values between 9.0 × 10−3 and 1.1 × 10−1. The C‐terminal domain of CwpV carries the antiphage activity and its deletion, or part of it, significantly reduced the antiphage protection. CwpV does not affect phage adsorption, but phage DNA replication is prevented, suggesting a mechanism reminiscent of superinfection exclusion systems normally encoded on prophages. CwpV thus represents a novel ubiquitous host‐encoded and phase‐variable antiphage system in C . difficile. PMID:26179020

  19. A noninterventional study evaluating the effectiveness of rotigotine and levodopa combination therapy in younger versus older patients with Parkinson's disease.

    PubMed

    Woitalla, Dirk; Dunac, Antoine; Safavi, Ali; Ceravolo, Maria-Gabriella; Gomez Esteban, Juan Carlos; Pavese, Nicola; Asgharnejad, Mahnaz; Joeres, Lars; Schuller, Jan-Christof; Chaudhuri, K Ray

    2018-06-19

    PD0013 was a 6-month noninterventional study in clinical practice comparing effectiveness/tolerability of rotigotine+levodopa in younger (<70 years) vs. older (≥70 years) Parkinson's disease (PD) patients. Patients previously received levodopa for ≥6 months as monotherapy/in combination with another dopamine-agonist (DA). Primary variable: Unified PD Rating Scale (UPDRS) Part-II change from baseline to end-of-observation-period (EOP). 91 younger/99 older patients started rotigotine; 68 younger/62 older patients completed the study. Most switched from levodopa+another DA. Addition of rotigotine as first DA was more common in older patients (20.2% vs.15.4%). Mean ± SD rotigotine-exposure: 6.1 ± 3.4 mg/24h younger vs. 4.9 ± 2.4 mg/24h older. Eleven patients changed levodopa dose. At EOP, improvement in mean UPDRS-II was greater in younger patients (p = 0.0289). UPDRS-II responder-rate (≥20% decrease in UPDRS-II score) was higher in younger patients (42.3% vs. 25.9%). Improvement across age groups was similar on PD Sleep Scale-2 and Clinical Global Impressions-Improvement Scale. Adverse drug reactions (ADRs), and discontinuations because of ADRs, were more common among older patients. There were no new safety signals. Despite low rotigotine doses, when added to levodopa/switched from levodopa+another DA, rotigotine led to greater improvement in UPDRS-II in younger patients (<70 years). Individual patient data revealed clinically meaningful improvements in UPDRS-II in both groups.

  20. Effects of the 2011 Tohoku Earthquake on VLBI Geode- tic Measurements

    NASA Astrophysics Data System (ADS)

    MacMillan, D.; Behrend, D.; Kurihara, S.

    2012-12-01

    The VLBI antenna TSUKUB32 at Tsukuba, Japan observes in 24-hour observing sessions once per week with the R1 operational network and on additional days with other networks on a more irregular basis. Further, the antenna is an endpoint of the single-baseline, 1-hr Intensive Int2 sessions observed on the weekends for the determination of UT1. TSUKUB32 returned to normal operational observing one month after the earthquake. The antenna is 160 km west and 240 km south of the epicenter of the Tohoku earthquake. We looked at the transient behavior of the TSUKUB32 position time series following the earthquake and found that significant deformation is continuing. The eastward rate relative to the long-term rate prior to the earthquake was about 20 cm/yr four months after the earthquake and 9 cm/yr after one year. The VLBI series agrees closely with the corresponding JPL (Jet Propulsion Laboratory) GPS series measured by the co-located GPS antenna TSUK. The co-seismic UEN displacement at Tsukuba as determined by VLBI was (-90 mm, 640 mm, 44 mm). We examined the effect of the variation of the TSUKUB32 position on EOP estimates and then used the GPS data to correct its position for the estimation of UT1 in the Tsukuba-Wettzell Int2 Intensive experiments. For this purpose and to provide operational UT1, the IVS scheduled a series of weekend Intensive sessions observing on the Kokee-Wettzell baseline immediately before each of the two Tsukuba-Wettzell Intensive sessions. Comparisons between the UT1 estimates from these weekend sessions and the USNO (United States Naval Observatory) combination series were used to validate the GPS correction to the TSUKUB32 position.

  1. Combinations of Earth Orientation Observations: SPACE94, COMB94, and POLE94

    NASA Technical Reports Server (NTRS)

    Gross, R. S.

    1995-01-01

    A Kalman filter has been used to combine all publicly available, independently determined measurements of the Earth's orientation taken by the modern, space-geodetic techniques of very long baseline interferometry, satellite laser ranging, lunar laser ranging, and the global positioning system. Prior to combining the data, tidal terms were removed from the UT1 measurements, outlying data points were deleted, series-specific corrections were applied for bias and rate, and the stated uncertainties of the measurements were adjusted by multiplying them by series-specific scale factors. Values for these bias- rate corrections and uncertainty scale factors were determined by an iterative, round-robin procedure wherein each data set is compared, in turn, to a combination of all other data sets. When applied to the measurements, the bias-rate corrections thus determined make the data sets agree with each other in bias and rate, and the uncertainty scale factors thus determined make the residual of each series (when differenced with a combination of all others) have a reduced chi-square of one. The corrected and adjusted series are then placed within an IERS reference frame by aligning them with the IERS Earth orientation series EOP (IERS)90C04. The result of combining these corrected, adjusted and aligned series is designated SPCE94 and spans October 6.0, 1976 to January 27.0, 1995 at daily intervals.

  2. New observational project for revealing natural and anthropogenic threats at the near-Earth space

    NASA Astrophysics Data System (ADS)

    Harutyunian, Haik A.; Nikoghosyan, Elena H.; Melikian, Norayr D.; Azatyan, Naira M.; Abrahamyan, Hayk V.; Paronyan, Gurgen M.; Andreasyan, Hasmik R.; Ohanian, Gabriel A.; Gevorgyan, Mkrtich H.; Mikayelyan, Gor A.

    2017-12-01

    In 2014, a new monitoring project started at the observational base Saravand of the Byurakan astrophysical observatory. This project initiated for revealing natural and artificial objects at the near-Earth space. This is a kind of continuation of earlier observational projects implemented at the observatory prior the collapse of Soviet Union. This time, near-Earth space monitoring is carried out at the request of the Russian agency ROSKOSMOS. For observations, the EOP-1 module is used, which includes small telescopes with a mirror diameter of 40cm, 25cm and 19cm.

  3. The Second International Celestial Reference Frame (ICRF2)

    NASA Technical Reports Server (NTRS)

    Ma, Chopo

    2010-01-01

    The ICRF2 catalog was constructed by the IERS/IVS Working Group with oversight by the IAU Working Group. Derived using data from August 1979 through March 2009, it is a great improvement over the original ICRF with 3414 extragalactic radio source positions, a noise floor of 40 microarcsec, and axis stability of 10 microarcsec. Significant refinements were made in the selection of defining sources, modeling, and the integration of CRF, TRF, and EOP. The adoption of the ICRF2 was approved by the IAU in Resolution B3 at the XXVII IAU General Assembly and became effective 1 January 2010.

  4. Stereotactic topography of the greater and third occipital nerves and its clinical implication.

    PubMed

    Kim, Hong-San; Shin, Kang-Jae; O, Jehoon; Kwon, Hyun-Jin; Lee, Minho; Yang, Hun-Mu

    2018-01-17

    This study aimed to provide topographic information of the greater occipital (GON) and third occipital (3ON) nerves, with the three-dimensional locations of their emerging points on the back muscles (60 sides, 30 cadavers) and their spatial relationship with muscle layers, using a 3D digitizer (Microscribe G2X, Immersion Corp, San Jose CA, USA). With reference to the external occipital protuberance (EOP), GON pierced the trapezius at a point 22.6 ± 7.4 mm lateral and 16.3 ± 5.9 mm inferior and the semispinalis capitis (SSC) at a point 13.1 ± 6.0 mm lateral and 27.7 ± 9.9 mm inferior. With the same reference, 3ON pierced, the trapezius at a point 12.9 ± 9.3 mm lateral and 44.2 ± 21.4 mm inferior, the splenius capitis at a point 10.0 ± 5.3 mm lateral and 59.2 ± 19.8 mm inferior, and SSC at a point 11.5 ± 9.9 mm lateral and 61.4 ± 15.3 mm inferior. Additionally, GON arose, winding up the obliquus capitis inferior, with the winding point located 52.3 ± 11.7 mm inferior to EOP and 30.2 ± 8.9 mm lateral to the midsagittal line. Knowing the course of GON and 3ON, from their emergence between vertebrae to the subcutaneous layer, is necessary for reliable nerve detection and precise analgesic injections. Moreover, stereotactic measurement using the 3D digitizer seems useful and accurate for neurovascular structure study.

  5. The effect of different surface treatments on the bond strength of a gingiva-colored indirect composite veneering material to three implant framework materials.

    PubMed

    Koizuka, Mai; Komine, Futoshi; Blatz, Markus B; Fushiki, Ryosuke; Taguchi, Kohei; Matsumura, Hideo

    2013-09-01

    To evaluate and compare the shear-bond strength of a gingiva-colored indirect composite material to three different implant framework materials (zirconia ceramics, gold alloy, and titanium), and to investigate the effect of surface pretreatment by air-particle abrasion and four priming agents. A gingiva-colored indirect composite (Ceramage) was bonded to three framework materials (n = 80): commercially pure titanium (CP- Ti ), ADA (American Dental Association)-type 4 casting gold alloy (Type IV), and zirconia ceramics (Zirconia) with or without airborne-particle abrasion. Before bonding, the surface of the specimens was treated using no (control) or one of four priming agents: Alloy Primer (ALP), Estenia Opaque Primer (EOP), Metal Link Primer (MLP), and V-Primer (VPR). Shear-bond strength was determined after 24-h wet storage. Data were analyzed using Steel-Dwass for multiple comparisons, and Mann-Whitney U-test (P = 0.05). For both CP- Ti and Zirconia substrates, three groups, ALP, EOP, and MLP, showed significantly higher bond strengths (P < 0.05) than the other groups with or without airborne-particle abrasion. For Type IV substrates, significantly higher bond strengths were obtained in ALP and MLP groups (P < 0.01) compared with the other groups with airborne-particle abrasion. Application of priming agents containing specific phosphoric ester groups significantly enhances the bond strength of a gingiva-colored composite material to commercially pure titanium and zirconia frameworks. Combined use of a thione monomer with a phosphoric monomer enhances the bond strengths to airborne-particle abraded type IV gold alloy. © 2012 John Wiley & Sons A/S.

  6. Obtaining accreditation by the pharmacy compounding accreditation board, part 2: developing essential standard operating procedures.

    PubMed

    Cabaleiro, Joe

    2007-01-01

    A key component of qualifying for accreditation with the Pharmacy Compounding Accreditation Board is having a set of comprehensive standard operating procedures that are being used by the pharmacy staff. The three criteria in standard operating procedures for which the Pharmacy Compounding Accreditation Board looks are: (1)written standard operating procedures; (2)standard operating procedures that reflect what the organization actualy does; and (3) whether the written standard operating procedures are implemented. Following specified steps in the preparation of standard operating procedures will result in procedures that meet Pharmacy Compounding Accreditation Board Requirements, thereby placing pharmacies one step closer to qualifying for accreditation.

  7. 40 CFR 792.81 - Standard operating procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false Standard operating procedures. 792.81... operating procedures. (a) A testing facility shall have standard operating procedures in writing, setting... data generated in the course of a study. All deviations in a study from standard operating procedures...

  8. 40 CFR 792.81 - Standard operating procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 33 2012-07-01 2012-07-01 false Standard operating procedures. 792.81... operating procedures. (a) A testing facility shall have standard operating procedures in writing, setting... data generated in the course of a study. All deviations in a study from standard operating procedures...

  9. 40 CFR 792.81 - Standard operating procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 32 2014-07-01 2014-07-01 false Standard operating procedures. 792.81... operating procedures. (a) A testing facility shall have standard operating procedures in writing, setting... data generated in the course of a study. All deviations in a study from standard operating procedures...

  10. U.S. Naval Observatory VLBI Analysis Center

    NASA Technical Reports Server (NTRS)

    Boboltz, David A.; Fey, Alan L.; Geiger, Nicole; Dieck, Chris; Hall, David M.

    2013-01-01

    This report summarizes the activities of the VLBI Analysis Center at the United States Naval Observatory for the 2012 calendar year. Over the course of the year, Analysis Center personnel continued analysis and timely submission of IVS-R4 databases for distribution to the IVS. During the 2012 calendar year, the USNO VLBI Analysis Center produced two VLBI global solutions designated as usn2012a and usn2012b. Earth orientation parameters (EOP) based on this solution and updated by the latest diurnal (IVS-R1 and IVS-R4) experiments were routinely submitted to the IVS. Sinex files based upon the bi-weekly 24-hour experiments were also submitted to the IVS. During the 2012 calendar year, Analysis Center personnel continued a program to use the Very Long Baseline Array (VLBA) operated by the NRAO for the purpose of measuring UT1-UTC. Routine daily 1-hour duration Intensive observations were initiated using the VLBA antennas at Pie Town, NM and Mauna Kea, HI. High-speed network connections to these two antennas are now routinely used for electronic transfer of VLBI data over the Internet to a USNO point of presence. A total of 270 VLBA Intensive experiments were observed and electronically transferred to and processed at USNO in 2012.

  11. 8 CFR 1003.40 - Local operating procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Local operating procedures. 1003.40 Section... PROVISIONS EXECUTIVE OFFICE FOR IMMIGRATION REVIEW Immigration Court-Rules of Procedure § 1003.40 Local... establish local operating procedures, provided that: (a) Such operating procedure(s) shall not be...

  12. 8 CFR 1003.40 - Local operating procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Local operating procedures. 1003.40 Section... PROVISIONS EXECUTIVE OFFICE FOR IMMIGRATION REVIEW Immigration Court-Rules of Procedure § 1003.40 Local... establish local operating procedures, provided that: (a) Such operating procedure(s) shall not be...

  13. NAME Modeling and Climate Process Team

    NASA Astrophysics Data System (ADS)

    Schemm, J. E.; Williams, L. N.; Gutzler, D. S.

    2007-05-01

    NAME Climate Process and Modeling Team (CPT) has been established to address the need of linking climate process research to model development and testing activities for warm season climate prediction. The project builds on two existing NAME-related modeling efforts. One major component of this project is the organization and implementation of a second phase of NAMAP, based on the 2004 season. NAMAP2 will re-examine the metrics proposed by NAMAP, extend the NAMAP analysis to transient variability, exploit the extensive observational database provided by NAME 2004 to analyze simulation targets of special interest, and expand participation. Vertical column analysis will bring local NAME observations and model outputs together in a context where key physical processes in the models can be evaluated and improved. The second component builds on the current NAME-related modeling effort focused on the diurnal cycle of precipitation in several global models, including those implemented at NCEP, NASA and GFDL. Our activities will focus on the ability of the operational NCEP Global Forecast System (GFS) to simulate the diurnal and seasonal evolution of warm season precipitation during the NAME 2004 EOP, and on changes to the treatment of deep convection in the complicated terrain of the NAMS domain that are necessary to improve the simulations, and ultimately predictions of warm season precipitation These activities will be strongly tied to NAMAP2 to ensure technology transfer from research to operations. Results based on experiments conducted with the NCEP CFS GCM will be reported at the conference with emphasis on the impact of horizontal resolution in predicting warm season precipitation over North America.

  14. 49 CFR 193.2503 - Operating procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...: FEDERAL SAFETY STANDARDS Operations § 193.2503 Operating procedures. Each operator shall follow one or more manuals of written procedures to provide safety in normal operation and in responding to an... 49 Transportation 3 2013-10-01 2013-10-01 false Operating procedures. 193.2503 Section 193.2503...

  15. 49 CFR 193.2503 - Operating procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...: FEDERAL SAFETY STANDARDS Operations § 193.2503 Operating procedures. Each operator shall follow one or more manuals of written procedures to provide safety in normal operation and in responding to an... 49 Transportation 3 2011-10-01 2011-10-01 false Operating procedures. 193.2503 Section 193.2503...

  16. 49 CFR 193.2503 - Operating procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...: FEDERAL SAFETY STANDARDS Operations § 193.2503 Operating procedures. Each operator shall follow one or more manuals of written procedures to provide safety in normal operation and in responding to an... 49 Transportation 3 2014-10-01 2014-10-01 false Operating procedures. 193.2503 Section 193.2503...

  17. 49 CFR 193.2503 - Operating procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...: FEDERAL SAFETY STANDARDS Operations § 193.2503 Operating procedures. Each operator shall follow one or more manuals of written procedures to provide safety in normal operation and in responding to an... 49 Transportation 3 2012-10-01 2012-10-01 false Operating procedures. 193.2503 Section 193.2503...

  18. Onsala Space Observatory: IVS Network Station

    NASA Technical Reports Server (NTRS)

    Haas, Ruediger; Elgered, Gunnar; Loefgren, Johan; Ning, Tong; Scherneck, Hans-Georg

    2013-01-01

    During 2012 we participated in 40 IVS sessions. As in the previous four years, we used the majority of the sessions that involved both Onsala and Tsukuba to do ultra-rapid dUT1 observations together with our colleagues in Tsukuba. We observed one four-station ultra-rapid EOP session together with Tsukuba, Hobart, and HartRAO. We also observed the RadioAstron satellite and several GLONASS satellites using the Onsala 25-m telescope. The highlight in 2012 was that our proposal to the Knut and Alice Wallenberg Foundation to establish a twin-telescope system at Onsala in accordance with the VLBI2010 recommendations was accepted.

  19. 40 CFR 160.81 - Standard operating procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Standard operating procedures. 160.81... GOOD LABORATORY PRACTICE STANDARDS Testing Facilities Operation § 160.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting forth study...

  20. 40 CFR 160.81 - Standard operating procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Standard operating procedures. 160.81... GOOD LABORATORY PRACTICE STANDARDS Testing Facilities Operation § 160.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting forth study...

  1. 40 CFR 160.81 - Standard operating procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Standard operating procedures. 160.81... GOOD LABORATORY PRACTICE STANDARDS Testing Facilities Operation § 160.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting forth study...

  2. Representing operations procedures using temporal dependency networks

    NASA Technical Reports Server (NTRS)

    Fayyad, Kristina E.; Cooper, Lynne P.

    1993-01-01

    DSN Link Monitor & Control (LMC) operations consist primarily of executing procedures to configure, calibrate, test, and operate a communications link between an interplanetary spacecraft and its mission control center. Currently the LMC operators are responsible for integrating procedures into an end-to-end series of steps. The research presented in this paper is investigating new ways of specifying operations procedures that incorporate the insight of operations, engineering, and science personnel to improve mission operations. The paper describes the rationale for using Temporal Dependency Networks (TDN's) to represent the procedures, a description of how the data is acquired, and the knowledge engineering effort required to represent operations procedures. Results of operational tests of this concept, as implemented in the LMC Operator Assistant Prototype (LMCOA), are also presented.

  3. The procedure execution manager and its application to Advanced Photon Source operation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Borland, M.

    1997-06-01

    The Procedure Execution Manager (PEM) combines a complete scripting environment for coding accelerator operation procedures with a manager application for executing and monitoring the procedures. PEM is based on Tcl/Tk, a supporting widget library, and the dp-tcl extension for distributed processing. The scripting environment provides support for distributed, parallel execution of procedures along with join and abort operations. Nesting of procedures is supported, permitting the same code to run as a top-level procedure under operator control or as a subroutine under control of another procedure. The manager application allows an operator to execute one or more procedures in automatic, semi-automatic,more » or manual modes. It also provides a standard way for operators to interact with procedures. A number of successful applications of PEM to accelerator operations have been made to date. These include start-up, shutdown, and other control of the positron accumulator ring (PAR), low-energy transport (LET) lines, and the booster rf systems. The PAR/LET procedures make nested use of PEM`s ability to run parallel procedures. There are also a number of procedures to guide and assist tune-up operations, to make accelerator physics measurements, and to diagnose equipment. Because of the success of the existing procedures, expanded use of PEM is planned.« less

  4. 34 CFR 602.23 - Operating procedures all agencies must have.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false Operating procedures all agencies must have. 602.23... Criteria for Recognition Required Operating Policies and Procedures § 602.23 Operating procedures all... that is related to the agency's standards or procedures. The agency may not complete its review and...

  5. 34 CFR 602.23 - Operating procedures all agencies must have.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false Operating procedures all agencies must have. 602.23... Criteria for Recognition Required Operating Policies and Procedures § 602.23 Operating procedures all... that is related to the agency's standards or procedures. The agency may not complete its review and...

  6. 34 CFR 602.23 - Operating procedures all agencies must have.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false Operating procedures all agencies must have. 602.23... Criteria for Recognition Required Operating Policies and Procedures § 602.23 Operating procedures all... that is related to the agency's standards or procedures. The agency may not complete its review and...

  7. 34 CFR 602.23 - Operating procedures all agencies must have.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Operating procedures all agencies must have. 602.23... Criteria for Recognition Required Operating Policies and Procedures § 602.23 Operating procedures all... that is related to the agency's standards or procedures. The agency may not complete its review and...

  8. D0 Central Tracking Solenoid Energization, Controls, Interlocks and Quench Protection Operating Procedures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hance, R.; /Fermilab

    1998-08-26

    This procedure is used when it is necessary to operate the solenoid energization, controls, interlocks and quench detection system. Note that a separate procedure exists for operating the solenoid 'cryogenic' systems. Only D0 Control Room Operators or the Project Electrical Engineer are qualified to execute these procedures or operate the solenoid system. This procedure assumes that the operator is familiar with using the Distributed Manufacturing Automation and Control Software (DMACS).

  9. Formalizing procedures for operations automation, operator training and spacecraft autonomy

    NASA Technical Reports Server (NTRS)

    Lecouat, Francois; Desaintvincent, Arnaud

    1994-01-01

    The generation and validation of operations procedures is a key task of mission preparation that is quite complex and costly. This has motivated the development of software applications providing support for procedures preparation. Several applications have been developed at MATRA MARCONI SPACE (MMS) over the last five years. They are presented in the first section of this paper. The main idea is that if procedures are represented in a formal language, they can be managed more easily with a computer tool and some automatic verifications can be performed. One difficulty is to define a formal language that is easy to use for operators and operations engineers. From the experience of the various procedures management tools developed in the last five years (including the POM, EOA, and CSS projects), MMS has derived OPSMAKER, a generic tool for procedure elaboration and validation. It has been applied to quite different types of missions, ranging from crew procedures (PREVISE system), ground control centers management procedures (PROCSU system), and - most relevant to the present paper - satellite operation procedures (PROCSAT developed for CNES, to support the preparation and verification of SPOT 4 operation procedures, and OPSAT for MMS telecom satellites operation procedures).

  10. The influence of the in situ camera calibration for direct georeferencing of aerial imagery

    NASA Astrophysics Data System (ADS)

    Mitishita, E.; Barrios, R.; Centeno, J.

    2014-11-01

    The direct determination of exterior orientation parameters (EOPs) of aerial images via GNSS/INS technologies is an essential prerequisite in photogrammetric mapping nowadays. Although direct sensor orientation technologies provide a high degree of automation in the process due to the GNSS/INS technologies, the accuracies of the obtained results depend on the quality of a group of parameters that models accurately the conditions of the system at the moment the job is performed. One sub-group of parameters (lever arm offsets and boresight misalignments) models the position and orientation of the sensors with respect to the IMU body frame due to the impossibility of having all sensors on the same position and orientation in the airborne platform. Another sub-group of parameters models the internal characteristics of the sensor (IOP). A system calibration procedure has been recommended by worldwide studies to obtain accurate parameters (mounting and sensor characteristics) for applications of the direct sensor orientation. Commonly, mounting and sensor characteristics are not stable; they can vary in different flight conditions. The system calibration requires a geometric arrangement of the flight and/or control points to decouple correlated parameters, which are not available in the conventional photogrammetric flight. Considering this difficulty, this study investigates the feasibility of the in situ camera calibration to improve the accuracy of the direct georeferencing of aerial images. The camera calibration uses a minimum image block, extracted from the conventional photogrammetric flight, and control point arrangement. A digital Vexcel UltraCam XP camera connected to POS AV TM system was used to get two photogrammetric image blocks. The blocks have different flight directions and opposite flight line. In situ calibration procedures to compute different sets of IOPs are performed and their results are analyzed and used in photogrammetric experiments. The IOPs from the in situ camera calibration improve significantly the accuracies of the direct georeferencing. The obtained results from the experiments are shown and discussed.

  11. 40 CFR 63.7733 - What procedures must I use to establish operating limits?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Foundries Initial Compliance Requirements § 63.7733 What procedures must I use to establish operating limits... site-specific operating limits in your operation and maintenance plan according to the procedures in... site-specific operating limit according to the procedures specified in paragraphs (c)(1) and (2) of...

  12. 40 CFR 63.7733 - What procedures must I use to establish operating limits?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Initial Compliance Requirements § 63.7733 What procedures must I use to establish operating limits? (a...-specific operating limits in your operation and maintenance plan according to the procedures in paragraphs... site-specific operating limit according to the procedures specified in paragraphs (c)(1) and (2) of...

  13. 40 CFR 63.7733 - What procedures must I use to establish operating limits?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Foundries Initial Compliance Requirements § 63.7733 What procedures must I use to establish operating limits... site-specific operating limits in your operation and maintenance plan according to the procedures in... site-specific operating limit according to the procedures specified in paragraphs (c)(1) and (2) of...

  14. 40 CFR 63.7733 - What procedures must I use to establish operating limits?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Foundries Initial Compliance Requirements § 63.7733 What procedures must I use to establish operating limits... site-specific operating limits in your operation and maintenance plan according to the procedures in... site-specific operating limit according to the procedures specified in paragraphs (c)(1) and (2) of...

  15. Representing Operations Procedures Using Temporal Dependency Algorithms

    NASA Technical Reports Server (NTRS)

    Fayyad, K.; Cooper, L.

    1992-01-01

    The research presented in this paper is investigating new ways of specifying operations procedures that incorporate the insight of operations, engineering, and science personnel to improve mission operations. The paper describes the rationale for using Temporal Dependency Networks to represent the procedures, a description of how the data is acquired, and the knowledge engineering effort required to represent operations procedures.

  16. Orbital operations study. Appendix B: Operational procedures

    NASA Technical Reports Server (NTRS)

    Galvin, D. M.; Mattson, H. L.; True, D. M.; Anderson, N. R.; Mehrbach, E.; Gianformaggio, A.; Steinwachs, W. L.; Turkel, S. H.

    1972-01-01

    Operational procedures for each alternate approach for each interfacing activity of the orbital operations study are presented. The applicability of the procedures to interfacing element pairs is identified.

  17. Test Operations Procedure (TOP) 03-2-827 Test Procedures for Video Target Scoring Using Calibration Lights

    DTIC Science & Technology

    2016-04-04

    Final 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Test Operations Procedure (TOP) 03-2-827 Test Procedures for Video Target Scoring Using...ABSTRACT This Test Operations Procedure (TOP) describes typical equipment and procedures to setup and operate a Video Target Scoring System (VTSS) to...lights. 15. SUBJECT TERMS Video Target Scoring System, VTSS, witness screens, camera, target screen, light pole 16. SECURITY

  18. In-office vs. operating room procedures for recurrent respiratory papillomatosis.

    PubMed

    Miller, Anya J; Gardner, Glendon M

    2017-01-01

    We conducted a study to analyze hospital and patient costs, outcomes, and patient satisfaction among adults undergoing in-office and operating room procedures for the treatment of recurrent respiratory papillomatosis. Our final study population was made up of 17 patients-1 man and 16 women, aged 30 to 86 years (mean: 62). The mean number of in-office laser procedures per patient was 4.2, and the mean interval between procedures was 5.4 months (although 10 patients underwent only 1 office procedure); the mean number of operating room procedures was 13.5, and the mean interval between procedures was 14.3 months. An equal number of patients reported complications or adverse events with the two types of procedures-5 each. The difference in cost between the office procedure (mean: $3,413.00) and the operating room procedure (mean: $12,382.59) was almost $9,000, but these savings were offset by the fact that the office procedures needed to be performed three times as often. Patients reported slightly more anxiety and discomfort during the office procedures and, overall, they appeared to prefer the operating room procedure. We conclude that office procedures are significantly more cost-effective than operating room procedures, but their use may be limited by patient tolerance and the increased frequency of the procedure.

  19. Fast neutron irradiation induced changes in the optical and thermal properties of modified polyvinyl chloride

    NASA Astrophysics Data System (ADS)

    Abou Taleb, W. M.; Madi, N. K.; Kassem, M. E.; El-Khatib, A. M.

    1996-05-01

    The effect of both dopant and neutron radiation on the optical and thermal properties of polyvinyl chloride (PVC) has been studied. The doped samples with Pb and Cd were irradiated with a 14 MeV-neutron fluence in the range 7-28.8 × 10 9 n/cm 2. The optical energy gap Eop exhibits a significant dependence on the type of additive and the neutron irradiation fluence. The specific heat at constant pressure Cp showed a nonmonotonical change with radiation fluence. The results of this study show that PVC:Pb behaves as a crystalline structure which is only slightly affected by neutron irradiation, while PVC:Cd is highly affected.

  20. Comparison of Realizations of the Terrestrial Reference Frame

    NASA Technical Reports Server (NTRS)

    Ma, C.; Macmillan, D.; Bolotin, S.; Le Bail, K.; Gordon, D.; Gipson, J.

    2015-01-01

    IGN and DGFI both generated realizations of the terrestrial reference frame under the auspices of the IERS from combination of the same space geodetic data. We compared the IGN and DGFI TRFs with a GSFC CALC/SOLVE TRF. WRMS position and velocity differences for the 40 most frequently observed sites were 2-3 mm and 0.3-0.4 mm/year. There was a scale difference of 0.39/0.09 ppb between the IGN/DGFI realizations and the GSFC solution. When we fixed positions and velocities to either the IGN or DGFI values in CALC/SOLVE solutions, the resulting EOP estimates were not significantly different from the estimates from a standard TRF solution.

  1. 76 FR 80261 - National Emission Standards for Hazardous Air Pollutants: Area Source Standards for Prepared...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... specifications and operating instructions, if available, or standard operating procedures must be developed by... manufacturer's specifications and operating instructions, if available, or standard operating procedures must... operating specifications or standard operating procedures developed by the prepared feeds manufacturer be...

  2. Pediatric Drowning: A Standard Operating Procedure to Aid the Prehospital Management of Pediatric Cardiac Arrest Resulting From Submersion.

    PubMed

    Best, Rebecca R; Harris, Benjamin H L; Walsh, Jason L; Manfield, Timothy

    2017-05-08

    Drowning is one of the leading causes of death in children. Resuscitating a child following submersion is a high-pressure situation, and standard operating procedures can reduce error. Currently, the Resuscitation Council UK guidance does not include a standard operating procedure on pediatric drowning. The objective of this project was to design a standard operating procedure to improve outcomes of drowned children. A literature review on the management of pediatric drowning was conducted. Relevant publications were used to develop a standard operating procedure for management of pediatric drowning. A concise standard operating procedure was developed for resuscitation following pediatric submersion. Specific recommendations include the following: the Heimlich maneuver should not be used in this context; however, prolonged resuscitation and therapeutic hypothermia are recommended. This standard operating procedure is a potentially useful adjunct to the Resuscitation Council UK guidance and should be considered for incorporation into its next iteration.

  3. 21 CFR 821.25 - Device tracking system and content requirements: manufacturer requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... accordance with its standard operating procedure of the information identified in paragraphs (a)(1), (a)(2... shall establish a written standard operating procedure for the collection, maintenance, and auditing of... standard operating procedure: (1) Data collection and recording procedures, which shall include a procedure...

  4. 40 CFR 160.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    .... (b) The written standard operating procedures required under § 160.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  5. 40 CFR 160.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... (b) The written standard operating procedures required under § 160.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  6. 40 CFR 160.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... (b) The written standard operating procedures required under § 160.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  7. 40 CFR 160.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... (b) The written standard operating procedures required under § 160.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  8. 40 CFR 160.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... (b) The written standard operating procedures required under § 160.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  9. Philosophy, policies, and procedures - The three P's of flight-deck operations

    NASA Technical Reports Server (NTRS)

    Degani, Asaf; Wiener, Earl L.

    1991-01-01

    Standard operating procedures are drafted and provided to flightcrews to dictate the manner in which tasks are carried out. Failure to conform to Standard Operating Procedures (SOP) is frequently listed as the cause of violations, incidents, and accidents. However, procedures are often designed piecemeal, rather than being based on a sound philosophy of operations and policies that follow from such a philosophy. A framework of philosophy, policies, and procedures is proposed.

  10. 40 CFR 63.7323 - What procedures must I use to establish operating limits?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... operating limit according to the procedures in paragraphs (c)(1), (2), or (3) of this section. (1) If you... establish a site-specific operating limit for pressure drop according to the procedures in paragraphs (d)(1... § 63.7290(a). (3) Establish revised operating limits according to the applicable procedures in...

  11. 40 CFR 63.7323 - What procedures must I use to establish operating limits?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... operating limit according to the procedures in paragraphs (c)(1), (2), or (3) of this section. (1) If you... establish a site-specific operating limit for pressure drop according to the procedures in paragraphs (d)(1... § 63.7290(a). (3) Establish revised operating limits according to the applicable procedures in...

  12. 40 CFR 63.7323 - What procedures must I use to establish operating limits?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... to the procedures in paragraphs (c)(1), (2), or (3) of this section. (1) If you elect the operating...-specific operating limit for pressure drop according to the procedures in paragraphs (d)(1) and (2) of this... § 63.7290(a). (3) Establish revised operating limits according to the applicable procedures in...

  13. 40 CFR 63.7323 - What procedures must I use to establish operating limits?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... operating limit according to the procedures in paragraphs (c)(1), (2), or (3) of this section. (1) If you... establish a site-specific operating limit for pressure drop according to the procedures in paragraphs (d)(1... § 63.7290(a). (3) Establish revised operating limits according to the applicable procedures in...

  14. 40 CFR 63.7323 - What procedures must I use to establish operating limits?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... operating limit according to the procedures in paragraphs (c)(1), (2), or (3) of this section. (1) If you... establish a site-specific operating limit for pressure drop according to the procedures in paragraphs (d)(1... § 63.7290(a). (3) Establish revised operating limits according to the applicable procedures in...

  15. 40 CFR 792.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... standardized. (b) The written standard operating procedures required under § 792.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  16. 40 CFR 792.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... standardized. (b) The written standard operating procedures required under § 792.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  17. 21 CFR 58.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... standardized. (b) The written standard operating procedures required under § 58.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  18. 40 CFR 792.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... standardized. (b) The written standard operating procedures required under § 792.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  19. 21 CFR 58.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... standardized. (b) The written standard operating procedures required under § 58.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  20. 21 CFR 58.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... standardized. (b) The written standard operating procedures required under § 58.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  1. 21 CFR 58.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... standardized. (b) The written standard operating procedures required under § 58.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  2. 40 CFR 792.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... standardized. (b) The written standard operating procedures required under § 792.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  3. 40 CFR 792.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... standardized. (b) The written standard operating procedures required under § 792.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  4. 21 CFR 58.63 - Maintenance and calibration of equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... standardized. (b) The written standard operating procedures required under § 58.81(b)(11) shall set forth in... maintenance operations were routine and followed the written standard operating procedures. Written records... operating procedures shall designate the person responsible for the performance of each operation. (c...

  5. 40 CFR 68.54 - Training.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... covered process have been trained or tested competent in the operating procedures provided in § 68.52 that... safely carry out the duties and responsibilities as provided in the operating procedures. (b) Refresher... operating procedures of the process. The owner or operator, in consultation with the employees operating the...

  6. 40 CFR 68.54 - Training.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... covered process have been trained or tested competent in the operating procedures provided in § 68.52 that... safely carry out the duties and responsibilities as provided in the operating procedures. (b) Refresher... operating procedures of the process. The owner or operator, in consultation with the employees operating the...

  7. 40 CFR 68.54 - Training.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... covered process have been trained or tested competent in the operating procedures provided in § 68.52 that... safely carry out the duties and responsibilities as provided in the operating procedures. (b) Refresher... operating procedures of the process. The owner or operator, in consultation with the employees operating the...

  8. 40 CFR 68.54 - Training.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... covered process have been trained or tested competent in the operating procedures provided in § 68.52 that... safely carry out the duties and responsibilities as provided in the operating procedures. (b) Refresher... operating procedures of the process. The owner or operator, in consultation with the employees operating the...

  9. 40 CFR 68.54 - Training.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... covered process have been trained or tested competent in the operating procedures provided in § 68.52 that... safely carry out the duties and responsibilities as provided in the operating procedures. (b) Refresher... operating procedures of the process. The owner or operator, in consultation with the employees operating the...

  10. 40 CFR 63.1547 - Monitoring requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... standard operating procedures manual that describes in detail the procedures for inspection, maintenance...) The standard operating procedures manual for baghouses required by paragraph (a) of this section shall... specified in the standard operating procedures manual for inspections and routine maintenance shall, at a...

  11. 40 CFR 63.1547 - Monitoring requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... standard operating procedures manual that describes in detail the procedures for inspection, maintenance...) The standard operating procedures manual for baghouses required by paragraph (a) of this section shall... specified in the standard operating procedures manual for inspections and routine maintenance shall, at a...

  12. Automated procedure execution for space vehicle autonomous control

    NASA Technical Reports Server (NTRS)

    Broten, Thomas A.; Brown, David A.

    1990-01-01

    Increased operational autonomy and reduced operating costs have become critical design objectives in next-generation NASA and DoD space programs. The objective is to develop a semi-automated system for intelligent spacecraft operations support. The Spacecraft Operations and Anomaly Resolution System (SOARS) is presented as a standardized, model-based architecture for performing High-Level Tasking, Status Monitoring and automated Procedure Execution Control for a variety of spacecraft. The particular focus is on the Procedure Execution Control module. A hierarchical procedure network is proposed as the fundamental means for specifying and representing arbitrary operational procedures. A separate procedure interpreter controls automatic execution of the procedure, taking into account the current status of the spacecraft as maintained in an object-oriented spacecraft model.

  13. 29 CFR 1915.508 - Training.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... responsibilities at all times; (2) Keep written standard operating procedures that address anticipated emergency... the employer's standard operating procedures; (5) Train new fire response employees before they engage in emergency operations; (6) At least quarterly, provide training on the written operating procedures...

  14. 29 CFR 1915.508 - Training.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... responsibilities at all times; (2) Keep written standard operating procedures that address anticipated emergency... the employer's standard operating procedures; (5) Train new fire response employees before they engage in emergency operations; (6) At least quarterly, provide training on the written operating procedures...

  15. 29 CFR 1915.508 - Training.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... responsibilities at all times; (2) Keep written standard operating procedures that address anticipated emergency... the employer's standard operating procedures; (5) Train new fire response employees before they engage in emergency operations; (6) At least quarterly, provide training on the written operating procedures...

  16. 29 CFR 1915.508 - Training.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... responsibilities at all times; (2) Keep written standard operating procedures that address anticipated emergency... the employer's standard operating procedures; (5) Train new fire response employees before they engage in emergency operations; (6) At least quarterly, provide training on the written operating procedures...

  17. 29 CFR 1915.508 - Training.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... responsibilities at all times; (2) Keep written standard operating procedures that address anticipated emergency... the employer's standard operating procedures; (5) Train new fire response employees before they engage in emergency operations; (6) At least quarterly, provide training on the written operating procedures...

  18. 21 CFR 58.81 - Standard operating procedures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Testing Facilities Operation § 58.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting... following: (1) Animal room preparation. (2) Animal care. (3) Receipt, identification, storage, handling...

  19. 21 CFR 58.81 - Standard operating procedures.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Testing Facilities Operation § 58.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting... following: (1) Animal room preparation. (2) Animal care. (3) Receipt, identification, storage, handling...

  20. 21 CFR 58.81 - Standard operating procedures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Testing Facilities Operation § 58.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting... following: (1) Animal room preparation. (2) Animal care. (3) Receipt, identification, storage, handling...

  1. 21 CFR 58.81 - Standard operating procedures.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Testing Facilities Operation § 58.81 Standard operating procedures. (a) A testing facility shall have standard operating procedures in writing setting... following: (1) Animal room preparation. (2) Animal care. (3) Receipt, identification, storage, handling...

  2. Characterizing diurnal and seasonal cycles in monsoon systems from TRMM and CEOP observations

    NASA Technical Reports Server (NTRS)

    Lau, William K. M.

    2006-01-01

    The CEOP Inter-Monsoon Study (CIMS) is one of the two main science drivers of CEOP that aims to (a) provide better understanding of fundamental physical processes in monsoon regions around the world, and (b) demonstrate the synergy and utility of CEOP data in providing a pathway for model physics evaluation and improvement. As the data collection phase for EOP-3 and EOP-4 is being completed, two full annual cycles (2003-2004) of research-quality data sets from satellites, reference sites, and model output location time series (MOLTS) have been processed and made available for data analyses and model validation studies. This article presents preliminary results of a CIMS study aimed at the characterization and intercomparison of all major monsoon systems. The CEOP reference site data proved its value in such exercises by being a powerful tool to cross-validate the TRMM data, and to intercompare with multi-model results in ongoing work. We use 6 years (1998-2003) of pentad CEOP/TRMM data with 2deg x 2.5deg latitude-longitude grid, over the domain of interests to define the monsoon climatological diurnal and annual cycles for the East Asian Monsoon (EAM), the South Asian Monsoon (SAM), the West Africa Monsoon (WAM), the North America/Mexican Monsoon (NAM), the South American Summer Monsoon (SASM) and the Australian Monsoon (AUM). As noted, the TRMM data used in the study were cross-validated using CEOP reference site data, where applicable. Results show that the observed diurnal cycle of rain peaked around late afternoon over monsoon land, and early morning over the oceans. The diurnal cycles in models tend to peak 2-3 hours earlier than observed. The seasonal cycles of the EAM and SAM show the strongest continentality, i.e, strong control by continental processes away from the ITCZ. The WAM, and the AUM shows the less continentality, i.e, strong control by the oceanic ITCZ.

  3. Characterizing Diurnal and Seasonal Cycles in Monsoon Systems from TRMM and CEOP Observations

    NASA Technical Reports Server (NTRS)

    Lau, William K. M.

    2007-01-01

    The CEOP Inter-Monsoon Study (CIMS) is one of the two main science drivers of CEOP that aims to (a) provide better understanding of fundamental physical processes in monsoon regions around the world, and (b) demonstrate the synergy and utility of CEOP data in providing a pathway for model physics evaluation and improvement. As the data collection phase for EOP-3 and EOP-4 is being completed, two full annual cycles (2003-2004) of research-quality data sets from satellites, reference sites, and model output location time series (MOLTS) have been processed and made available for data analyses and model validation studies. This article presents preliminary results of a CIMS study aimed at the characterization and intercomparison of all major monsoon systems. The CEOP reference site data proved its value in such exercises by being a powerful tool to cross-validate the TRMM data, and to intercompare with multi-model results in ongoing work. We use 6 years (1998-2003) of pentad CEOP/TRMM data with 2 deg x 2.5 deg. latitude-longitude grid, over the domain of interests to define the monsoon climatological diurnal and annual cycles for the East Asian Monsoon (EAM), the South Asian Monsoon (SAM), the West Africa Monsoon (WAM), the North America/Mexican Monsoon (NAM), the South American Summer Monsoon (SASM) and the Australian Monsoon (AUM). As noted, the TRMM data used in the study were cross-validated using CEOP reference site data, where applicable. Results show that the observed diurnal cycle of rain peaked around late afternoon over monsoon land, and early morning over the oceans. The diurnal cycles in models tend to peak 2-3 hours earlier than observed. The seasonal cycles of the EAM and SAM show the strongest continentality, i.e, strong control by continental processes away from the ITCZ. The WAM, and the AUM shows the less continentality, i.e, strong control by the oceanic ITCZ.

  4. IGS preparations for the next reprocessing and ITRF

    NASA Astrophysics Data System (ADS)

    Griffiths, J.; Rebischung, P.; Garayt, B.; Ray, J.

    2012-04-01

    The International GNSS Service (IGS) is preparing for a second reanalysis of the full history of data collected by the global network using the latest models and methodologies. This effort is designed to obtain improved, consistent satellite orbits, station and satellite clocks, Earth orientation parameters (EOPs) and terrestrial frame products using the current IGS framework, IGS08/igs08.atx. It follows a successful first reprocessing campaign, which provided the IGS input to ITRF2008. Likewise, this second campaign (repro2) should provide the IGS contribution to the next ITRF. We will discuss the analysis standards adopted for repro2, including treatment of and mitigation against non-tidal loading effects, and improvements expected with respect to the first reprocessing campaign. International Earth Rotation and Reference Systems Service (IERS) Conventions of 2010 are expected to be implemented. Though, no improvements in the diurnal and semidiurnal EOP tide models will be made, so associated errors will remain. Adoption of new orbital force models and consistent handling of satellite attitude changes are expected to improve IGS clock and orbit products. A priori Earth-reflected radiation pressure models should nearly eliminate the ~2.5 cm orbit radial bias previously observed using laser ranging methods. Also, a priori modeling of radiation forces exerted in signal transmission should improve the orbit products. And use of consistent satellite attitude models should help with satellite clock estimation during Earth and Moon eclipses. Improvements of the terrestrial frame products are expected from, for example, the inclusion of second order ionospheric corrections and also the a priori modeling of Earth-reflected radiation pressure. Because of remaining unmodeled orbital forces, systematic errors will however likely continue to affect the origin of the repro2 frames and prevent a contribution of GNSS to the origin of the next ITRF. On the other hand, the planned inclusion of satellite phase center offsets in the long-term stacking of the repro2 frames could help in defining the scale rate of the next ITRF.

  5. High Frequency Variations in Earth Orientation Derived From GNSS Observations

    NASA Astrophysics Data System (ADS)

    Weber, R.; Englich, S.; Snajdrova, K.; Boehm, J.

    2006-12-01

    Current observations gained by the space geodetic techniques, especially VLBI, GPS and SLR, allow for the determination of Earth Orientation Parameters (EOPs - polar motion, UT1/LOD, nutation offsets) with unprecedented accuracy and temporal resolution. This presentation focuses on contributions to the EOP recovery provided by satellite navigation systems (primarily GPS). The IGS (International GNSS Service), for example, currently provides daily polar motion with an accuracy of less than 0.1mas and LOD estimates with an accuracy of a few microseconds. To study more rapid variations in polar motion and LOD we established in a first step a high resolution (hourly resolution) ERP-time series from GPS observation data of the IGS network covering the period from begin of 2005 till March 2006. The calculations were carried out by means of the Bernese GPS Software V5.0 considering observations from a subset of 79 fairly stable stations out of the IGb00 reference frame sites. From these ERP time series the amplitudes of the major diurnal and semidiurnal variations caused by ocean tides are estimated. After correcting the series for ocean tides the remaining geodetic observed excitation is compared with variations of atmospheric excitation (AAM). To study the sensitivity of the estimates with respect to the applied mapping function we applied both the widely used NMF (Niell Mapping Function) and the VMF1 (Vienna Mapping Function 1). In addition, based on computations covering two months in 2005, the potential improvement due to the use of additional GLONASS data will be discussed. Finally, satellite techniques are also able to provide nutation offset rates with respect to the most recent nutation model. Based on GPS observations from 2005 we established nutation rate time series and subsequently derived the amplitudes of several nutation waves with periods less than 30 days. The results are compared to VLBI estimates processed by means of the OCCAM 6.1 software.

  6. 76 FR 80314 - National Emission Standards for Hazardous Air Pollutants: Area Source Standards for Prepared...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... operating instructions, if available, or standard operating procedures must be developed by the facility... operating instructions, if available, or standard operating procedures must be developed by the facility... standard operating procedures developed by the prepared feeds manufacturer be required as part of the...

  7. 40 CFR 63.1547 - Monitoring requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... according to, a standard operating procedures manual that describes in detail the procedures for inspection...) The standard operating procedures manual for baghouses required by paragraph (a) of this section must... specified in the standard operating procedures manual for inspections and routine maintenance must, at a...

  8. 40 CFR 63.1547 - Monitoring requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... according to, a standard operating procedures manual that describes in detail the procedures for inspection...) The standard operating procedures manual for baghouses required by paragraph (a) of this section must... specified in the standard operating procedures manual for inspections and routine maintenance must, at a...

  9. 40 CFR 63.1547 - Monitoring requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... according to, a standard operating procedures manual that describes in detail the procedures for inspection...) The standard operating procedures manual for baghouses required by paragraph (a) of this section must... specified in the standard operating procedures manual for inspections and routine maintenance must, at a...

  10. Apollo Operations Handbook Lunar Module (LM 11 and Subsequent) Vol. 2 Operational Procedures

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The Apollo Operations Handbook (AOH) is the primary means of documenting LM descriptions and procedures. The AOH is published in two separately bound volumes. This information is useful in support of program management, engineering, test, flight simulation, and real time flight support efforts. This volume contains crew operational procedures: normal, backup, abort, malfunction, and emergency. These procedures define the sequence of actions necessary for safe and efficient subsystem operation.

  11. 47 CFR 36.412 - Apportionment procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROCEDURES; STANDARD PROCEDURES FOR SEPARATING TELECOMMUNICATIONS PROPERTY COSTS, REVENUES, EXPENSES, TAXES AND RESERVES FOR TELECOMMUNICATIONS COMPANIES 1 Operating Expenses and Taxes Operating Taxes § 36.412... groups as follows: (1) Operating Federal, State and local income taxes and (2) all other operating taxes...

  12. Procedures in complex systems: the airline cockpit.

    PubMed

    Degani, A; Wiener, E L

    1997-05-01

    In complex human-machine systems, successful operations depend on an elaborate set of procedures which are specified by the operational management of the organization. These procedures indicate to the human operator (in this case the pilot) the manner in which operational management intends to have various tasks done. The intent is to provide guidance to the pilots and to ensure a safe, logical, efficient, and predictable (standardized) means of carrying out the objectives of the job. However, procedures can become a hodge-podge. Inconsistent or illogical procedures may lead to noncompliance by operators. Based on a field study with three major airlines, the authors propose a model for procedure development called the "Four P's": philosophy, policies, procedures, and practices. Using this model as a framework, the authors discuss the intricate issue of designing flight-deck procedures, and propose a conceptual approach for designing any set of procedures. The various factors, both external and internal to the cockpit, that must be considered for procedure design are presented. In particular, the paper addresses the development of procedures for automated cockpits--a decade-long, and highly controversial issue in commercial aviation. Although this paper is based on airline operations, we assume that the principles discussed here are also applicable to other high-risk supervisory control systems, such as space flight, manufacturing process control, nuclear power production, and military operations.

  13. 40 CFR 63.548 - Monitoring requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) You must prepare, and at all times operate according to, a standard operating procedures manual that...) You must submit the standard operating procedures manual for baghouses required by paragraph (a) of... that you specify in the standard operating procedures manual for inspections and routine maintenance...

  14. 40 CFR 63.548 - Monitoring requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) You must prepare, and at all times operate according to, a standard operating procedures manual that...) You must submit the standard operating procedures manual for baghouses required by paragraph (a) of... that you specify in the standard operating procedures manual for inspections and routine maintenance...

  15. 40 CFR 63.548 - Monitoring requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) You must prepare, and at all times operate according to, a standard operating procedures manual that...) You must submit the standard operating procedures manual for baghouses required by paragraph (a) of... that you specify in the standard operating procedures manual for inspections and routine maintenance...

  16. 40 CFR 63.1549 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... recordkeeping required as part of the practices described in the standard operating procedures manual for... as part of the practices described in the standard operating procedures manual for baghouses required... procedures outlined in the standard operating procedures manual required by § 63.1544(a) were not followed...

  17. 40 CFR 63.1549 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... recordkeeping required as part of the practices described in the standard operating procedures manual for... as part of the practices described in the standard operating procedures manual for baghouses required... procedures outlined in the standard operating procedures manual required by § 63.1544(a) were not followed...

  18. 40 CFR 63.1549 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... recordkeeping required as part of the practices described in the standard operating procedures manual for... as part of the practices described in the standard operating procedures manual for baghouses required... procedures outlined in the standard operating procedures manual required by § 63.1544(a) were not followed...

  19. 49 CFR 193.2713 - Training: operations and maintenance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... maintenance activities; and (iii) To carry out aspects of the operating and maintenance procedures under... instructions on the facility operations, including controls, functions, and operating procedures; and (ii) To understand the LNG transfer procedures provided under § 193.2513. (b) A written plan of continuing...

  20. 49 CFR 193.2713 - Training: operations and maintenance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... maintenance activities; and (iii) To carry out aspects of the operating and maintenance procedures under... instructions on the facility operations, including controls, functions, and operating procedures; and (ii) To understand the LNG transfer procedures provided under § 193.2513. (b) A written plan of continuing...

  1. 49 CFR 193.2713 - Training: operations and maintenance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... maintenance activities; and (iii) To carry out aspects of the operating and maintenance procedures under... instructions on the facility operations, including controls, functions, and operating procedures; and (ii) To understand the LNG transfer procedures provided under § 193.2513. (b) A written plan of continuing...

  2. 49 CFR 193.2713 - Training: operations and maintenance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... maintenance activities; and (iii) To carry out aspects of the operating and maintenance procedures under... instructions on the facility operations, including controls, functions, and operating procedures; and (ii) To understand the LNG transfer procedures provided under § 193.2513. (b) A written plan of continuing...

  3. 49 CFR 193.2713 - Training: operations and maintenance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... maintenance activities; and (iii) To carry out aspects of the operating and maintenance procedures under... instructions on the facility operations, including controls, functions, and operating procedures; and (ii) To understand the LNG transfer procedures provided under § 193.2513. (b) A written plan of continuing...

  4. 49 CFR 325.39 - Measurement procedure; highway operations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false Measurement procedure; highway operations. 325.39... MOTOR CARRIER NOISE EMISSION STANDARDS Measurement of Noise Emissions; Highway Operations § 325.39 Measurement procedure; highway operations. (a) In accordance with the rules in this subpart, a measurement...

  5. 49 CFR 325.39 - Measurement procedure; highway operations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 5 2012-10-01 2012-10-01 false Measurement procedure; highway operations. 325.39... MOTOR CARRIER NOISE EMISSION STANDARDS Measurement of Noise Emissions; Highway Operations § 325.39 Measurement procedure; highway operations. (a) In accordance with the rules in this subpart, a measurement...

  6. 49 CFR 325.39 - Measurement procedure; highway operations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Measurement procedure; highway operations. 325.39... MOTOR CARRIER NOISE EMISSION STANDARDS Measurement of Noise Emissions; Highway Operations § 325.39 Measurement procedure; highway operations. (a) In accordance with the rules in this subpart, a measurement...

  7. Operational Control Procedures for the Activated Sludge Process, Part III-A: Calculation Procedures.

    ERIC Educational Resources Information Center

    West, Alfred W.

    This is the second in a series of documents developed by the National Training and Operational Technology Center describing operational control procedures for the activated sludge process used in wastewater treatment. This document deals exclusively with the calculation procedures, including simplified mixing formulas, aeration tank…

  8. 46 CFR 130.480 - Test procedure and operations manual.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Test procedure and operations manual. 130.480 Section... VESSEL CONTROL, AND MISCELLANEOUS EQUIPMENT AND SYSTEMS Automation of Unattended Machinery Spaces § 130.480 Test procedure and operations manual. (a) A procedure for tests to be conducted on automated...

  9. NHEXAS PHASE I MARYLAND STUDY--STANDARD OPERATING PROCEDURE FOR PREPARATION OF STANDARD OPERATING PROCEDURES (G01)

    EPA Science Inventory

    The purpose of this SOP is to develop a consistent method and style for all Emory University/Harvard University/Johns Hopkins University standard operating procedures. SOPs are necessary to document all procedures, methods, and techniques used in the NHEXAS investigations. Deve...

  10. Operative record using intraoperative digital data in neurosurgery.

    PubMed

    Houkin, K; Kuroda, S; Abe, H

    2000-01-01

    The purpose of this study was to develop a new method for more efficient and accurate operative records using intra-operative digital data in neurosurgery, including macroscopic procedures and microscopic procedures under an operating microscope. Macroscopic procedures were recorded using a digital camera and microscopic procedures were also recorded using a microdigital camera attached to an operating microscope. Operative records were then recorded digitally and filed in a computer using image retouch software and database base software. The time necessary for editing of the digital data and completing the record was less than 30 minutes. Once these operative records are digitally filed, they are easily transferred and used as database. Using digital operative records along with digital photography, neurosurgeons can document their procedures more accurately and efficiently than by the conventional method (handwriting). A complete digital operative record is not only accurate but also time saving. Construction of a database, data transfer and desktop publishing can be achieved using the intra-operative data, including intra-operative photographs.

  11. Nothing Fails Like Success: The Search for an Intelligent Paradigm for Studying Intelligence.

    DTIC Science & Technology

    1980-10-01

    n’ first, the chicken or the 0g(1. Fctor scores can h( rr on COIp nWent N -.ors,_ ; co:,ion(,nt , iees can to r’grOl :.’ed on f, ’,r ,, r, What e...OP-S " 7I Washingtcn, DC 2袆 1 Dr. Alfred F. -Xico TrLining PAn ;ysis & Evluaticn Grcup (TAFG) Dept. cf the Navy Orlando, FL � 1 W. Gitry...Director Attn: PFRT-nKF i Army F’ s,-;rch Irast.i .utc ~. i. sAFB. AZ 5 Th?’ SDO1~ Fir,icwer !venu-2 Alex-n fri , , VA 2??V S M)T~f/T~ tcp ~ :;~ r.~~iAFB

  12. VLBI-SLR Combination Solution Using GEODYN

    NASA Technical Reports Server (NTRS)

    MacMillan, Dan; Pavlis, Despina; Lemoine, Frank; Chinn, Douglas; Rowlands, David

    2010-01-01

    We would like to generate a multi-technique solution combining all of the geodetic techniques (VLBI, SLR, GPS, and DORIS) using the same software and using the same a priori models. Here we use GEODYN software and consider only the VLBI-SLR combination. Here we report initial results of our work on the combination. We first performed solutions with GEODYN using only VLBI data and found that VLBI EOP solution results produced with GEODYN agree with results using CALC/SOLVE at the 1-sigma level. We then combined the VLBI normal equations in GEODYN with weekly SLR normal equations for the period 2007-2008. Agreement of estimated Earth orientation parameters with IERS C04 were not significantly different for the VLBI-only, SLR-only, and VLBI+SLR solutions

  13. A Guide for Developing Standard Operating Job Procedures for the Pump Station Process Wastewater Treatment Facility. SOJP No. 3.

    ERIC Educational Resources Information Center

    Perley, Gordon F.

    This is a guide for standard operating job procedures for the pump station process of wastewater treatment plants. Step-by-step instructions are given for pre-start up inspection, start-up procedures, continuous routine operation procedures, and shut-down procedures. A general description of the equipment used in the process is given. Two…

  14. On the design of flight-deck procedures

    DOT National Transportation Integrated Search

    1994-06-01

    In complex human-machine systems, operations, training, and standardization depend on an elaborate set of procedures which are specified and mandated by the operational management of the organization. These procedures indicate to the human operator (...

  15. 14 CFR 61.87 - Solo requirements for student pilots.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... flight preparation procedures, including preflight planning and preparation, powerplant operation, and...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...

  16. 14 CFR 61.87 - Solo requirements for student pilots.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... flight preparation procedures, including preflight planning and preparation, powerplant operation, and...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...

  17. 14 CFR 61.87 - Solo requirements for student pilots.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... flight preparation procedures, including preflight planning and preparation, powerplant operation, and...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...

  18. 14 CFR 61.87 - Solo requirements for student pilots.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... flight preparation procedures, including preflight planning and preparation, powerplant operation, and...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...

  19. 14 CFR 61.87 - Solo requirements for student pilots.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... flight preparation procedures, including preflight planning and preparation, powerplant operation, and...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...) Proper flight preparation procedures, including preflight planning and preparation, powerplant operation...

  20. 47 CFR 80.116 - Radiotelephone operating procedures for ship stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Radiotelephone operating procedures for ship... Procedures-Ship Stations § 80.116 Radiotelephone operating procedures for ship stations. (a) Calling coast stations. (1) Use by ship stations of the frequency 2182 kHz for calling coast stations and for replying to...

  1. 47 CFR 80.116 - Radiotelephone operating procedures for ship stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Radiotelephone operating procedures for ship... Procedures-Ship Stations § 80.116 Radiotelephone operating procedures for ship stations. (a) Calling coast stations. (1) Use by ship stations of the frequency 2182 kHz for calling coast stations and for replying to...

  2. 47 CFR 80.116 - Radiotelephone operating procedures for ship stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Radiotelephone operating procedures for ship... Procedures-Ship Stations § 80.116 Radiotelephone operating procedures for ship stations. (a) Calling coast stations. (1) Use by ship stations of the frequency 2182 kHz for calling coast stations and for replying to...

  3. 47 CFR 80.116 - Radiotelephone operating procedures for ship stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Radiotelephone operating procedures for ship... Procedures-Ship Stations § 80.116 Radiotelephone operating procedures for ship stations. (a) Calling coast stations. (1) Use by ship stations of the frequency 2182 kHz for calling coast stations and for replying to...

  4. 47 CFR 80.116 - Radiotelephone operating procedures for ship stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Radiotelephone operating procedures for ship... Procedures-Ship Stations § 80.116 Radiotelephone operating procedures for ship stations. (a) Calling coast stations. (1) Use by ship stations of the frequency 2182 kHz for calling coast stations and for replying to...

  5. Basics of compounding: considerations for implementing United States pharmacopeia chapter 797 pharmaceutical compounding-sterile preparations, part 16: suggested standard operating procedures.

    PubMed

    Okeke, Claudia C; Allen, Loyd V

    2009-01-01

    The standard operating procedures suggested in this article are presented to compounding pharmacies to ensure the quality of the environment in which a CSP is prepared. Since United States Pharmacopeia Chapter 797 provides minimum standards, each facility should aim for best practice gold standard. The standard operating procedures should be tailored to meet the expectations and design of each facility. Compounding personnel are expected to know and understand each standard operating procedure to allow for complete execution of the procedures.

  6. Test Operations Procedure (TOP) 08-2-188 Chemical Point Detector Vapor Testing

    DTIC Science & Technology

    2018-04-27

    Evaluation Command 6617 Aberdeen Boulevard Aberdeen Proving Ground, MD 21005-5001 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S...AND EVALUATION COMMAND TEST OPERATIONS PROCEDURE *Test Operations Procedure 08-2-188 27 April 2018 DTIC AD No. CHEMICAL POINT DETECTOR VAPOR...188 27 April 2018 2 1. SCOPE. This Test Operations Procedure (TOP), which has been endorsed by the Test and Evaluation Capabilities and

  7. Designing Flight-Deck Procedures

    NASA Technical Reports Server (NTRS)

    Degani, Asaf; Wiener, L.; Shafto, Mike (Technical Monitor)

    1995-01-01

    A complex human-machine system consists of more than merely one or more human operators and a collection of hardware components. In order to operate a complex system successfully, the human-machine system must be supported by an organizational infrastructure of operating concepts, rules, guidelines, and documents. The coherency of such operating concepts, in terms of consistency and logic, is vitally important for the efficiency and safety of any complex system. In high-risk endeavors such as aircraft operations, space flight, nuclear power production, manufacturing process control, and military operations, it is essential that such support be flawless, as the price of operational error can be high. When operating rules are not adhered to, or the rules are inadequate for the task at hand, not only will the system's goals be thwarted, but there may also be tragic human and material consequences. To ensure safe and predictable operations, support to the operators, in this case flight crews, often comes in the form of standard operating procedures. These provide the crew with step-by-step guidance for carrying out their operations. Standard procedures do indeed promote uniformity, but they do so at the risk of reducing the role of human operators to a lower level. Management, however, must recognize the danger of over-procedurization, which fails to exploit one of the most valuable assets in the system, the intelligent operator who is "on the scene." The alert system designer and operations manager recognize that there cannot be a procedure for everything, and the time will come in which the operators of a complex system will face a situation for which there is no written procedure. Procedures, whether executed by humans or machines, have their place, but so does human cognition.

  8. Apollo-Soyuz test project. Operations handbook command/service/docking modules (CSM 119/DM 1): Operational procedures reference issue

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Operational and configuration checks for the Apollo-Soyuz Test Project are presented. The checks include: backup crew prelaunch, prime crew prelaunch, boost and insertion, G and C reference data, G and N reference modes, rendezvous, navigation, Apollo-Soyuz operations, abort procedures, and emergency procedures.

  9. Future of operating rooms.

    PubMed

    Reijnen, Michel M P J; Zeebregts, Clark J; Meijerink, Wilhelmus J H J

    2005-01-01

    Operating-room design has not changed significantly since the modern era of surgery began. Minimal invasive, endoscopic, procedures, and evolution of technology will affect operating-room design in the near future. Poor ergonomics has always been one of the major drawbacks of endoscopic surgery. Use of retractable arms and monitors will improve ergonomics of the operating team. Developments in telecommunication will allow surgeons to communicate with colleagues and experts during the procedure in virtually any location around the world, which increases teaching possibilities and procedural safety. Introduction and further development of intraoperative imaging, including real-time, three-dimensional (3-D) reconstructions of patient, and computer-aided surgery offer surgeons the opportunity to train the planned surgical procedure. Moreover, they will improve control and supervision of the procedure in learning situations. The last decade's robotics have made their introduction into the operating rooms. They improve control over the operating-room environment and will facilitate the performance of more complex procedures. However, high costs and lack of force feedback remain its major drawbacks. Improvements of robotic techniques and its implementation into the operating rooms will further guide their design into highly specialized operating units.

  10. 40 CFR 68.52 - Operating procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 2 Prevention Program § 68.52 Operating procedures. (a) The... for safely conducting activities associated with each covered process consistent with the safety information for that process. Operating procedures or instructions provided by equipment manufacturers or...

  11. Outcomes of PCI in Relation to Procedural Characteristics and Operator Volumes in the United States.

    PubMed

    Fanaroff, Alexander C; Zakroysky, Pearl; Dai, David; Wojdyla, Daniel; Sherwood, Matthew W; Roe, Matthew T; Wang, Tracy Y; Peterson, Eric D; Gurm, Hitinder S; Cohen, Mauricio G; Messenger, John C; Rao, Sunil V

    2017-06-20

    Professional guidelines have reduced the recommended minimum number to an average of 50 percutaneous coronary intervention (PCI) procedures performed annually by each operator. Operator volume patterns and associated outcomes since this change are unknown. The authors describe herein PCI operator procedure volumes; characteristics of low-, intermediate-, and high-volume operators; and the relationship between operator volume and clinical outcomes in a large, contemporary, nationwide sample. Using data from the National Cardiovascular Data Registry collected between July 1, 2009, and March 31, 2015, we examined operator annual PCI volume. We divided operators into low- (<50 PCIs per year), intermediate- (50 to 100 PCIs per year), and high- (>100 PCIs per year) volume groups, and determined the adjusted association between annual PCI volume and in-hospital outcomes, including mortality. The median annual number of procedures performed per operator was 59; 44% of operators performed <50 PCI procedures per year. Low-volume operators more frequently performed emergency and primary PCI procedures and practiced at hospitals with lower annual PCI volumes. Unadjusted in-hospital mortality was 1.86% for low-volume operators, 1.73% for intermediate-volume operators, and 1.48% for high-volume operators. The adjusted risk of in-hospital mortality was higher for PCI procedures performed by low- and intermediate-volume operators compared with those performed by high-volume operators (adjusted odds ratio: 1.16 for low versus high; adjusted odds ratio: 1.05 for intermediate vs. high volume) as was the risk for new dialysis post PCI. No volume relationship was observed for post-PCI bleeding. Many PCI operators in the United States are performing fewer than the recommended number of PCI procedures annually. Although absolute risk differences are small and may be partially explained by unmeasured differences in case mix between operators, there remains an inverse relationship between PCI operator volume and in-hospital mortality that persisted in risk-adjusted analyses. Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  12. Learning curve in transradial cardiac catheterization: procedure-related parameters stratified by operators' transradial volume.

    PubMed

    Kasasbeh, Ehab S; Parvez, Babar; Huang, Robert L; Hasselblad, Michele Marie; Glazer, Mark D; Salloum, Joseph G; Cleator, John H; Zhao, David X

    2012-11-01

    To determine whether radial artery access is associated with a reduction in fluoroscopy time, procedure time, and other procedural variables over a 27-month period during which the radial artery approach was incorporated in a single academic Medical Center. Although previous studies have demonstrated a relationship between increased volume and decreased procedural time, no studies have looked at the integration of radial access over time. Data were collected from consecutive patients who presented to the Vanderbilt University Medical Center cardiac catheterization laboratory from January 1, 2009 to April 1, 2011. Patients who underwent radial access diagnostic catheterization with and without percutaneous coronary intervention were included in this study. A total of 1112 diagnostic cardiac catheterizations through the radial access site were analyzed. High-volume, intermediate-volume, and low-volume operators were grouped based on the percentage of procedures performed through a radial approach. From 2009 to 2011, there was a significant decrease in fluoroscopy time in all operator groups for diagnostic catheterization (P=.035). The high-volume operator group had 1.88 and 3.66 minute reductions in fluoroscopy time compared to the intermediate- and low-volume operator groups, respectively (both P<.001). Likewise, the intermediate-volume operator group had a 1.77 minute improvement compared to the low-volume operator group, but this did not reach statistical significance (P=.102). The improvement in fluoroscopy time and other procedure-related parameters was seen after approximately 25 cases with further improvement after 75 cases. The incorporation of the radial access approach in the cardiac catheterization laboratory led to a decrease in fluoroscopy time for each operator and operator group over the last 3 years. Our data demonstrated that higher-volume radial operators have better procedure, room, and fluoroscopy times when compared to intermediate- and low-volume operators. However, lower-volume operators have a reduction in procedure-related parameters with increased radial cases. Number of procedures needed to become sufficient was demonstrated in the current study.

  13. 14 CFR 125.287 - Initial and recurrent pilot testing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... TRANSPORTATION (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS... air navigation aids appropriate to the operation of pilot authorization, including, when applicable, instrument approach facilities and procedures; (5) Air traffic control procedures, including IFR procedures...

  14. 7 CFR 610.23 - State Technical Committee meetings.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Technical Committee member. (b) NRCS will establish and maintain national standard operating procedures... standard operating procedures will outline items such as: The best practice approach to establishing... standard operating procedures established under paragraph (b) of this section, the State Conservationist...

  15. 7 CFR 610.23 - State Technical Committee meetings.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Technical Committee member. (b) NRCS will establish and maintain national standard operating procedures... standard operating procedures will outline items such as: The best practice approach to establishing... standard operating procedures established under paragraph (b) of this section, the State Conservationist...

  16. 7 CFR 610.23 - State Technical Committee meetings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Technical Committee member. (b) NRCS will establish and maintain national standard operating procedures... standard operating procedures will outline items such as: The best practice approach to establishing... standard operating procedures established under paragraph (b) of this section, the State Conservationist...

  17. 7 CFR 610.23 - State Technical Committee meetings.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Technical Committee member. (b) NRCS will establish and maintain national standard operating procedures... standard operating procedures will outline items such as: The best practice approach to establishing... standard operating procedures established under paragraph (b) of this section, the State Conservationist...

  18. 7 CFR 610.23 - State Technical Committee meetings.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Technical Committee member. (b) NRCS will establish and maintain national standard operating procedures... standard operating procedures will outline items such as: The best practice approach to establishing... standard operating procedures established under paragraph (b) of this section, the State Conservationist...

  19. Computerized procedures system

    DOEpatents

    Lipner, Melvin H.; Mundy, Roger A.; Franusich, Michael D.

    2010-10-12

    An online data driven computerized procedures system that guides an operator through a complex process facility's operating procedures. The system monitors plant data, processes the data and then, based upon this processing, presents the status of the current procedure step and/or substep to the operator. The system supports multiple users and a single procedure definition supports several interface formats that can be tailored to the individual user. Layered security controls access privileges and revisions are version controlled. The procedures run on a server that is platform independent of the user workstations that the server interfaces with and the user interface supports diverse procedural views.

  20. IDS contribution to ITRF2008

    NASA Astrophysics Data System (ADS)

    Valette, Jean-Jacques; Lemoine, Frank G.; Ferrage, Pascale; Yaya, Philippe; Altamimi, Zuheir; Willis, Pascal; Soudarin, Laurent

    2010-12-01

    For the first time, the International DORIS Service (IDS) has produced a technique level combination based on the contributions of seven analysis centers (ACs), including the European Space Operations Center (ESOC), Geodetic Observatory Pecny (GOP), Geoscience Australia (GAU), the NASA Goddard Space Flight Center (GSFC), the Institut Géographique National (IGN), the Institute of Astronomy, Russian Academy of Sciences (INASAN, named as INA), and CNES/CLS (named as LCA). The ACs used five different software packages to process the DORIS data from 1992 to 2008, including NAPEOS (ESA), Bernese (GOP), GEODYN (GAU, GSC), GIPSY/OASIS (INA), and GINS (LCA). The data from seven DORIS satellites, TOPEX/Poseidon, SPOT-2, SPOT-3, SPOT-4, SPOT-5, Envisat and Jason-1 were processed and all the analysis centers produced weekly SINEX files in either variance-covariance or normal equation format. The processing by the analysis centers used the latest GRACE-derived gravity models, forward modelling of atmospheric gravity, updates to the radiation pressure modelling to improve the DORIS geocenter solutions, denser parameterization of empirically determined drag coefficients to improve station and EOP solutions, especially near the solar maximum in 2001-2002, updated troposphere mapping functions, and an ITRF2005-derived station set for orbit determination, DPOD2005. The CATREF software was used to process the weekly AC solutions, and produce three iterations of an IDS global weekly combination. Between the development of the initial solution IDS-1, and the final solution, IDS-3, the ACs improved their analysis strategies and submitted updated solutions to eliminate troposphere-derived biases in the solution scale, to reduce drag-related degradations in station positioning, and to refine the estimation strategy to improve the combination geocenter solution. An analysis of the frequency content of the individual AC geocenter and scale solutions was used as the basis to define the scale and geocenter of the IDS-3 combination. The final IDS-3 combination has an internal position consistency (WRMS) that is 15 to 20 mm before 2002 and 8 to 10 mm after 2002, when 4 or 5 satellites contribute to the weekly solutions. The final IDS-3 combination includes solutions for 130 DORIS stations on 67 different sites of which 35 have occupations over 16 years (1993.0-2009.0). The EOPs from the IDS-3 combination were compared with the IERS 05 C04 time series and the RMS agreement was 0.24 mas and 0.35 mas for the X and Y components of polar motion. The comparison to ITRF2005 in station position shows an agreement of 6 to 8 mm RMS in horizontal and 10.3 mm in height. The RMS comparison to ITRF2005 in station velocity is at 1.8 mm/year on the East component, to 1.2 mm/year in North component and 1.6 mm/year in height.

  1. A prospective outcomes analysis of palliative procedures performed for malignant intestinal obstruction due to recurrent ovarian cancer.

    PubMed

    Chi, Dennis S; Phaëton, Rebecca; Miner, Thomas J; Kardos, Steven V; Diaz, John P; Leitao, Mario M; Gardner, Ginger; Huh, Jae; Tew, William P; Konner, Jason A; Sonoda, Yukio; Abu-Rustum, Nadeem R; Barakat, Richard R; Jaques, David P

    2009-08-01

    To obtain prospective outcomes data on patients (pts) undergoing palliative operative or endoscopic procedures for malignant bowel obstruction due to recurrent ovarian cancer. An institutional study was conducted from July 2002 to July 2003 to prospectively identify pts who underwent an operative or endoscopic procedure to palliate the symptoms of advanced cancer. This report focuses on pts with malignant bowel obstruction due to recurrent ovarian cancer. Procedures performed with an upper or lower gastrointestinal (GI) endoscope were considered "endoscopic." All other cases were classified as "operative." Following the procedure, the presence or absence of symptoms was determined and followed over time. All pts were followed until death. Palliative interventions were performed on 74 gynecologic oncology pts during the study period, of which 26 (35%) were for malignant GI obstruction due to recurrent ovarian cancer. The site of obstruction was small bowel in 14 (54%) cases and large bowel in 12 (46%) cases. Palliative procedures were operative in 14 (54%) pts and endoscopic in the other 12 (46%). Overall, symptomatic improvement or resolution within 30 days was achieved in 23 (88%) of 26 patients, with 1 (4%) postprocedure mortality. At 60 days, 10 (71%) of 14 pts who underwent operative procedures and 6 (50%) of 12 pts who had endoscopic procedures had symptom control. Median survival from the time of the palliative procedure was 191 days (range, 33-902) for those undergoing an operative procedure and 78 days (range, 18-284) for those undergoing an endoscopic procedure. Patients with malignant bowel obstructions due to recurrent ovarian cancer have a high likelihood of experiencing relief of symptoms with palliative procedures. Although recurrence of symptoms is common, durable palliation and extended survival are possible, especially in those patients selected for operative intervention.

  2. 40 CFR 63.9622 - What test methods and other procedures must I use to establish and demonstrate initial compliance...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...-specific operating limits according to the procedures in paragraphs (a)(1) through (3) of this section. (1... establish site-specific operating limits according to the procedures in paragraphs (b)(1) and (2) of this... site-specific operating limit according to the procedures in paragraphs (c)(1) or (2) of this section...

  3. 40 CFR 63.9622 - What test methods and other procedures must I use to establish and demonstrate initial compliance...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...-specific operating limits according to the procedures in paragraphs (a)(1) through (3) of this section. (1... establish site-specific operating limits according to the procedures in paragraphs (b)(1) and (2) of this... site-specific operating limit according to the procedures in paragraphs (c)(1) or (2) of this section...

  4. 40 CFR 63.9622 - What test methods and other procedures must I use to establish and demonstrate initial compliance...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...-specific operating limits according to the procedures in paragraphs (a)(1) through (3) of this section. (1... establish site-specific operating limits according to the procedures in paragraphs (b)(1) and (2) of this... site-specific operating limit according to the procedures in paragraphs (c)(1) or (2) of this section...

  5. 40 CFR 63.9622 - What test methods and other procedures must I use to establish and demonstrate initial compliance...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...-specific operating limits according to the procedures in paragraphs (a)(1) through (3) of this section. (1... establish site-specific operating limits according to the procedures in paragraphs (b)(1) and (2) of this... site-specific operating limit according to the procedures in paragraphs (c)(1) or (2) of this section...

  6. 40 CFR 63.9622 - What test methods and other procedures must I use to establish and demonstrate initial compliance...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-specific operating limits according to the procedures in paragraphs (a)(1) through (3) of this section. (1... establish site-specific operating limits according to the procedures in paragraphs (b)(1) and (2) of this... site-specific operating limit according to the procedures in paragraphs (c)(1) or (2) of this section...

  7. 21 CFR 680.1 - Allergenic Products.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Mold manufacturers shall maintain written standard operating procedures, developed by a qualified... representative species of mold subject to the standard operating procedures. The tests shall be performed at each manufacturing step during and subsequent to harvest, as specified in the standard operating procedures. Before...

  8. 21 CFR 680.1 - Allergenic Products.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Mold manufacturers shall maintain written standard operating procedures, developed by a qualified... representative species of mold subject to the standard operating procedures. The tests shall be performed at each manufacturing step during and subsequent to harvest, as specified in the standard operating procedures. Before...

  9. 21 CFR 680.1 - Allergenic Products.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Mold manufacturers shall maintain written standard operating procedures, developed by a qualified... representative species of mold subject to the standard operating procedures. The tests shall be performed at each manufacturing step during and subsequent to harvest, as specified in the standard operating procedures. Before...

  10. 21 CFR 680.1 - Allergenic Products.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Mold manufacturers shall maintain written standard operating procedures, developed by a qualified... representative species of mold subject to the standard operating procedures. The tests shall be performed at each manufacturing step during and subsequent to harvest, as specified in the standard operating procedures. Before...

  11. 14 CFR 23.1585 - Operating procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Operating procedures. 23.1585 Section 23.1585 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... Information Airplane Flight Manual and Approved Manual Material § 23.1585 Operating procedures. (a) For all...

  12. 10 CFR 455.62 - Contents of a technical assistance program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... and document energy conservation maintenance and operating procedure changes and energy conservation... operating procedure changes, if any, and energy conservation measures selected in accordance with the State... conservation maintenance and operating procedure change and an estimate of the costs of adopting such energy...

  13. 10 CFR 455.62 - Contents of a technical assistance program.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... and document energy conservation maintenance and operating procedure changes and energy conservation... operating procedure changes, if any, and energy conservation measures selected in accordance with the State... conservation maintenance and operating procedure change and an estimate of the costs of adopting such energy...

  14. 10 CFR 455.62 - Contents of a technical assistance program.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... and document energy conservation maintenance and operating procedure changes and energy conservation... operating procedure changes, if any, and energy conservation measures selected in accordance with the State... conservation maintenance and operating procedure change and an estimate of the costs of adopting such energy...

  15. 10 CFR 455.62 - Contents of a technical assistance program.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... and document energy conservation maintenance and operating procedure changes and energy conservation... operating procedure changes, if any, and energy conservation measures selected in accordance with the State... conservation maintenance and operating procedure change and an estimate of the costs of adopting such energy...

  16. 40 CFR 63.550 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... recordkeeping required as part of the practices described in the standard operating procedures manual for... part of the practices described in the standard operating procedures manual for baghouses required... period, including an explanation of the periods when the procedures outlined in the standard operating...

  17. 40 CFR 63.550 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... recordkeeping required as part of the practices described in the standard operating procedures manual for... part of the practices described in the standard operating procedures manual for baghouses required... period, including an explanation of the periods when the procedures outlined in the standard operating...

  18. 10 CFR 455.62 - Contents of a technical assistance program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... and document energy conservation maintenance and operating procedure changes and energy conservation... operating procedure changes, if any, and energy conservation measures selected in accordance with the State... conservation maintenance and operating procedure change and an estimate of the costs of adopting such energy...

  19. Technical Operating Procedures for Resource Documentation Under the Oil Pollution Act of 1990

    DOT National Transportation Integrated Search

    1996-06-01

    Technical Operating Procedures (TOPs) for Resource Documentation under the Oil Pollution Act of 1990 (P.L.101-380) have been developed to provide guidance to users operating as, or in support of, the Federal On-Scene Coordinator(FOSC). The procedures...

  20. 47 CFR 1.957 - Procedure with respect to amateur radio operator license.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Procedure with respect to amateur radio... AND PROCEDURE Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.957 Procedure with respect to amateur radio operator license. Each candidate for an amateur...

  1. 47 CFR 1.957 - Procedure with respect to amateur radio operator license.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... AND PROCEDURE Grants by Random Selection Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.957 Procedure with respect to amateur radio operator license. Each... 47 Telecommunication 1 2013-10-01 2013-10-01 false Procedure with respect to amateur radio...

  2. 47 CFR 1.957 - Procedure with respect to amateur radio operator license.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... AND PROCEDURE Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.957 Procedure with respect to amateur radio operator license. Each candidate for an amateur... 47 Telecommunication 1 2011-10-01 2011-10-01 false Procedure with respect to amateur radio...

  3. 47 CFR 1.957 - Procedure with respect to amateur radio operator license.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... AND PROCEDURE Grants by Random Selection Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.957 Procedure with respect to amateur radio operator license. Each... 47 Telecommunication 1 2014-10-01 2014-10-01 false Procedure with respect to amateur radio...

  4. 47 CFR 1.957 - Procedure with respect to amateur radio operator license.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... AND PROCEDURE Grants by Random Selection Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.957 Procedure with respect to amateur radio operator license. Each... 47 Telecommunication 1 2012-10-01 2012-10-01 false Procedure with respect to amateur radio...

  5. Operational Control Procedures for the Activated Sludge Process, Part III-B: Calculation Procedures for Step-Feed Process Responses and Addendum No. 1.

    ERIC Educational Resources Information Center

    West, Alfred W.

    This is the third in a series of documents developed by the National Training and Operational Technology Center describing operational control procedures for the activated sludge process used in wastewater treatment. This document deals with the calculation procedures associated with a step-feed process. Illustrations and examples are included to…

  6. Impact of operator experience and training strategy on procedural outcomes with leadless pacing: Insights from the Micra Transcatheter Pacing Study.

    PubMed

    El-Chami, Mikhael; Kowal, Robert C; Soejima, Kyoko; Ritter, Philippe; Duray, Gabor Z; Neuzil, Petr; Mont, Lluis; Kypta, Alexander; Sagi, Venkata; Hudnall, John Harrison; Stromberg, Kurt; Reynolds, Dwight

    2017-07-01

    Leadless pacemaker systems have been designed to avoid the need for a pocket and transvenous lead. However, delivery of this therapy requires a new catheter-based procedure. This study evaluates the role of operator experience and different training strategies on procedural outcomes. A total of 726 patients underwent implant attempt with the Micra transcatheter pacing system (TPS; Medtronic, Minneapolis, MN, USA) by 94 operators trained in a teaching laboratory using a simulator, cadaver, and large animal models (lab training) or locally at the hospital with simulator/demo model and proctorship (hospital training). Procedure success, procedure duration, fluoroscopy time, and safety outcomes were compared between training methods and experience (implant case number). The Micra TPS procedure was successful in 99.2% of attempts and did not differ between the 55 operators trained in the lab setting and the 39 operators trained locally at the hospital (P = 0.189). Implant case number was also not a determinant of procedural success (P = 0.456). Each operator performed between one and 55 procedures. Procedure time and fluoroscopy duration decreased by 2.0% (P = 0.002) and 3.2% (P < 0.001) compared to the previous case. Major complication rate and pericardial effusion rate were not associated with case number (P = 0.755 and P = 0.620, respectively). There were no differences in the safety outcomes by training method. Among a large group of operators, implantation success was high regardless of experience. While procedure duration and fluoroscopy times decreased with implant number, complications were low and not associated with case number. Procedure and safety outcomes were similar between distinct training methodologies. © 2017 Wiley Periodicals, Inc.

  7. 10 CFR 26.127 - Procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., implement, and maintain written standard operating procedures for each assay performed for drug and specimen... facility shall develop, implement, and maintain written standard operating procedures for each test. The...; (2) Preparation of reagents, standards, and controls; (3) Calibration procedures; (4) Derivation of...

  8. 10 CFR 26.127 - Procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., implement, and maintain written standard operating procedures for each assay performed for drug and specimen... facility shall develop, implement, and maintain written standard operating procedures for each test. The...; (2) Preparation of reagents, standards, and controls; (3) Calibration procedures; (4) Derivation of...

  9. 10 CFR 26.127 - Procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., implement, and maintain written standard operating procedures for each assay performed for drug and specimen... facility shall develop, implement, and maintain written standard operating procedures for each test. The...; (2) Preparation of reagents, standards, and controls; (3) Calibration procedures; (4) Derivation of...

  10. Imaging System for Vaginal Surgery.

    PubMed

    Taylor, G Bernard; Myers, Erinn M

    2015-12-01

    The vaginal surgeon is challenged with performing complex procedures within a surgical field of limited light and exposure. The video telescopic operating microscope is an illumination and imaging system that provides visualization during open surgical procedures with a limited field of view. The imaging system is positioned within the surgical field and then secured to the operating room table with a maneuverable holding arm. A high-definition camera and Xenon light source allow transmission of the magnified image to a high-definition monitor in the operating room. The monitor screen is positioned above the patient for the surgeon and assistants to view real time throughout the operation. The video telescopic operating microscope system was used to provide surgical illumination and magnification during total vaginal hysterectomy and salpingectomy, midurethral sling, and release of vaginal scar procedures. All procedures were completed without complications. The video telescopic operating microscope provided illumination of the vaginal operative field and display of the magnified image onto high-definition monitors in the operating room for the surgeon and staff to simultaneously view the procedures. The video telescopic operating microscope provides high-definition display, magnification, and illumination during vaginal surgery.

  11. Navigation Architecture for a Space Mobile Network

    NASA Technical Reports Server (NTRS)

    Valdez, Jennifer E.; Ashman, Benjamin; Gramling, Cheryl; Heckler, Gregory W.; Carpenter, Russell

    2016-01-01

    The Tracking and Data Relay Satellite System (TDRSS) Augmentation Service for Satellites (TASS) is a proposed beacon service to provide a global, space based GPS augmentation service based on the NASA Global Differential GPS (GDGPS) System. The TASS signal will be tied to the GPS time system and usable as an additional ranging and Doppler radiometric source. Additionally, it will provide data vital to autonomous navigation in the near Earth regime, including space weather information, TDRS ephemerides, Earth Orientation Parameters (EOP), and forward commanding capability. TASS benefits include enhancing situational awareness, enabling increased autonomy, and providing near real-time command access for user platforms. As NASA Headquarters' Space Communication and Navigation Office (SCaN) begins to move away from a centralized network architecture and towards a Space Mobile Network (SMN) that allows for user initiated services, autonomous navigation will be a key part of such a system. This paper explores how a TASS beacon service enables the Space Mobile Networking paradigm, what a typical user platform would require, and provides an in-depth analysis of several navigation scenarios and operations concepts. This paper provides an overview of the TASS beacon and its role within the SMN and user community. Supporting navigation analysis is presented for two user mission scenarios: an Earth observing spacecraft in low earth orbit (LEO), and a highly elliptical spacecraft in a lunar resonance orbit. These diverse flight scenarios indicate the breadth of applicability of the TASS beacon for upcoming users within the current network architecture and in the SMN.

  12. 49 CFR 192.605 - Procedural manual for operations, maintenance, and emergencies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... operations and maintenance activities are conducted. (b) Maintenance and normal operations. The manual... personnel to determine the effectiveness, and adequacy of the procedures used in normal operation and... or flow rate outside normal operating limits; (iii) Loss of communications; (iv) Operation of any...

  13. Medium- and Long-term Prediction of LOD Change with the Leap-step Autoregressive Model

    NASA Astrophysics Data System (ADS)

    Liu, Q. B.; Wang, Q. J.; Lei, M. F.

    2015-09-01

    It is known that the accuracies of medium- and long-term prediction of changes of length of day (LOD) based on the combined least-square and autoregressive (LS+AR) decrease gradually. The leap-step autoregressive (LSAR) model is more accurate and stable in medium- and long-term prediction, therefore it is used to forecast the LOD changes in this work. Then the LOD series from EOP 08 C04 provided by IERS (International Earth Rotation and Reference Systems Service) is used to compare the effectiveness of the LSAR and traditional AR methods. The predicted series resulted from the two models show that the prediction accuracy with the LSAR model is better than that from AR model in medium- and long-term prediction.

  14. The Prediction of Length-of-day Variations Based on Gaussian Processes

    NASA Astrophysics Data System (ADS)

    Lei, Y.; Zhao, D. N.; Gao, Y. P.; Cai, H. B.

    2015-01-01

    Due to the complicated time-varying characteristics of the length-of-day (LOD) variations, the accuracies of traditional strategies for the prediction of the LOD variations such as the least squares extrapolation model, the time-series analysis model, and so on, have not met the requirements for real-time and high-precision applications. In this paper, a new machine learning algorithm --- the Gaussian process (GP) model is employed to forecast the LOD variations. Its prediction precisions are analyzed and compared with those of the back propagation neural networks (BPNN), general regression neural networks (GRNN) models, and the Earth Orientation Parameters Prediction Comparison Campaign (EOP PCC). The results demonstrate that the application of the GP model to the prediction of the LOD variations is efficient and feasible.

  15. 21 CFR 821.25 - Device tracking system and content requirements: manufacturer requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... manufacturer of a tracked device shall keep current records in accordance with its standard operating procedure... this section. A manufacturer shall make this standard operating procedure available to FDA upon request. A manufacturer shall incorporate the following into the standard operating procedure: (1) Data...

  16. 40 CFR 63.1549 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the practices described in the standard operating procedures manual required under § 63.1544(a) for... described in the standard operating procedures manual for baghouses required under § 63.1547(a). (6) If an... in the standard operating procedures manual for baghouses required under § 63.1547(a), including an...

  17. 40 CFR 63.545 - Standards for fugitive dust sources.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... according to a standard operating procedures manual that describes in detail the measures that will be put... standard operating procedures manual shall be submitted to the Administrator or delegated authority for review and approval. (c) The controls specified in the standard operating procedures manual shall at a...

  18. 40 CFR 63.545 - Standards for fugitive dust sources.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... according to a standard operating procedures manual that describes in detail the measures that will be put... standard operating procedures manual shall be submitted to the Administrator or delegated authority for review and approval. (c) The controls specified in the standard operating procedures manual shall at a...

  19. 40 CFR 63.1549 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the practices described in the standard operating procedures manual required under § 63.1544(a) for... described in the standard operating procedures manual for baghouses required under § 63.1547(a). (6) If an... in the standard operating procedures manual for baghouses required under § 63.1547(a), including an...

  20. 21 CFR 821.25 - Device tracking system and content requirements: manufacturer requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... manufacturer of a tracked device shall keep current records in accordance with its standard operating procedure... this section. A manufacturer shall make this standard operating procedure available to FDA upon request. A manufacturer shall incorporate the following into the standard operating procedure: (1) Data...

  1. 40 CFR 63.550 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., corrective action, report, or record, according to § 63.10(b)(1). (b) The standard operating procedures... standard operating procedures manual for baghouses required under § 63.548(a). (4) Electronic records of... required as part of the practices described in the standard operating procedures manual required under § 63...

  2. 21 CFR 821.25 - Device tracking system and content requirements: manufacturer requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... manufacturer of a tracked device shall keep current records in accordance with its standard operating procedure... this section. A manufacturer shall make this standard operating procedure available to FDA upon request. A manufacturer shall incorporate the following into the standard operating procedure: (1) Data...

  3. 40 CFR 63.550 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., corrective action, report, or record, according to § 63.10(b)(1). (b) The standard operating procedures... standard operating procedures manual for baghouses required under § 63.548(a). (4) Electronic records of... required as part of the practices described in the standard operating procedures manual required under § 63...

  4. 21 CFR 821.25 - Device tracking system and content requirements: manufacturer requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... manufacturer of a tracked device shall keep current records in accordance with its standard operating procedure... this section. A manufacturer shall make this standard operating procedure available to FDA upon request. A manufacturer shall incorporate the following into the standard operating procedure: (1) Data...

  5. 40 CFR 63.550 - Recordkeeping and reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., corrective action, report, or record, according to § 63.10(b)(1). (b) The standard operating procedures... standard operating procedures manual for baghouses required under § 63.548(a). (4) Electronic records of... required as part of the practices described in the standard operating procedures manual required under § 63...

  6. 76 FR 54528 - Standard Operating Procedures (SOP) of the Aircraft Certification Service (AIR) Process for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ...) of the Aircraft Certification Service (AIR) Process for the Sequencing of Certification and... on the Aircraft Certification Service (AIR) standard operating procedure (SOP) describing the process... comments on the SOP : AIR-100-001; Standard Operating Procedure--Aircraft Certification Service Project...

  7. 42 CFR 35.15 - Consent to operative procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Consent to operative procedures. 35.15 Section 35.15 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICAL CARE AND EXAMINATIONS HOSPITAL AND STATION MANAGEMENT General § 35.15 Consent to operative procedures. Except in...

  8. 42 CFR 35.15 - Consent to operative procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Consent to operative procedures. 35.15 Section 35.15 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICAL CARE AND EXAMINATIONS HOSPITAL AND STATION MANAGEMENT General § 35.15 Consent to operative procedures. Except in...

  9. 42 CFR 35.15 - Consent to operative procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Consent to operative procedures. 35.15 Section 35.15 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICAL CARE AND EXAMINATIONS HOSPITAL AND STATION MANAGEMENT General § 35.15 Consent to operative procedures. Except in...

  10. 42 CFR 35.15 - Consent to operative procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Consent to operative procedures. 35.15 Section 35.15 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICAL CARE AND EXAMINATIONS HOSPITAL AND STATION MANAGEMENT General § 35.15 Consent to operative procedures. Except in...

  11. 42 CFR 35.15 - Consent to operative procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Consent to operative procedures. 35.15 Section 35.15 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICAL CARE AND EXAMINATIONS HOSPITAL AND STATION MANAGEMENT General § 35.15 Consent to operative procedures. Except in...

  12. "Knife to skin" time is a poor marker of operating room utilization and efficiency in cardiac surgery.

    PubMed

    Luthra, Suvitesh; Ramady, Omar; Monge, Mary; Fitzsimons, Michael G; Kaleta, Terry R; Sundt, Thoralf M

    2015-06-01

    Markers of operation room (OR) efficiency in cardiac surgery are focused on "knife to skin" and "start time tardiness." These do not evaluate the middle and later parts of the cardiac surgical pathway. The purpose of this analysis was to evaluate knife to skin time as an efficiency marker in cardiac surgery. We looked at knife to skin time, procedure time, and transfer times in the cardiac operational pathway for their correlation with predefined indices of operational efficiency (Index of Operation Efficiency - InOE, Surgical Index of Operational Efficiency - sInOE). A regression analysis was performed to test the goodness of fit of the regression curves estimated for InOE relative to the times on the operational pathway. The mean knife to skin time was 90.6 ± 13 minutes (23% of total OR time). The mean procedure time was 282 ± 123 minutes (71% of total OR time). Utilization efficiencies were highest for aortic valve replacement and coronary artery bypass grafting and least for complex aortic procedures. There were no significant procedure-specific or team-specific differences for standard procedures. Procedure times correlated the strongest with InOE (r = -0.98, p < 0.01). Compared to procedure times, knife to skin is not as strong an indicator of efficiency. A statistically significant linear dependence on InOE was observed with "procedure times" only. Procedure times are a better marker of OR efficiency than knife to skin in cardiac cases. Strategies to increase OR utilization and efficiency should address procedure times in addition to knife to skin times. © 2015 Wiley Periodicals, Inc.

  13. Comparable operative times with and without surgery resident participation.

    PubMed

    Uecker, John; Luftman, Kevin; Ali, Sadia; Brown, Carlos

    2013-01-01

    Both physicians and patients may perceive that having surgical residents participate in operative procedures may prolong operations and worsen outcomes. We hypothesized that resident participation would prolong operative times and potentially adversely affect postoperative outcomes. To evaluate the effect of general surgery resident participation in surgical procedures on operative times and postoperative patient outcomes. Retrospective study of general surgery procedures performed during two 1-year time periods, 2007 without residents and 2011 with residents. Procedures included laparoscopic appendectomy and cholecystectomy, thyroidectomy, breast procedure, hernia repair, lower extremity amputation, tunneled venous catheter, and percutaneous endoscopic gastrostomy. The primary outcome was operative time and secondary outcomes included length of stay (LOS) and mortality. Academic general surgery residency program. There were 2280 operative procedures performed during the 2 periods: 1150 with resident involvement (RES group) and 1130 without residents (NORES group). The RES and NORES groups were similar for patient age (42 vs 41, p = 0.14) and male gender (46% vs 45%, p = 0.68), and there was no difference in overall operative time (68min vs 66min, p = 0.58). More specifically there was no difference in operative time (minutes) for specific procedures including laparoscopic appendectomy (67 vs 71, p = 0.8), thyroidectomy (125 vs 109, p = 0.16), breast procedure (38 vs 26, p = 0.79), hernia repair (61 vs 60, p = 0.74), lower extremity amputation (65 vs 77, p = 0.16), tunneled venous catheter (49 vs 47, p = 0.75), and percutaneous endoscopic gastrostomy (49 vs 46, p = 0.76). However, laparoscopic cholecystectomy took slightly longer in the RES group (71 vs 66, p = 0.02). LOS was shorter during the year with resident involvement (2.6 days vs 3.7 days, p = 0.0004) and there was no difference in mortality (0.17% vs 0.35%, p = 0.45). There is no difference in operative time for common general surgery procedures with or without resident involvement. In addition, resident involvement is associated with a decrease in LOS. This information should be used to change physician and patient negative perceptions regarding resident involvement while performing surgical procedures. © 2013 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  14. 47 CFR 36.374 - Telephone operator services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... JURISDICTIONAL SEPARATIONS PROCEDURES; STANDARD PROCEDURES FOR SEPARATING TELECOMMUNICATIONS PROPERTY COSTS... Customer Operations Expenses § 36.374 Telephone operator services. (a) Expenses in this classification include costs incurred for operators in call completion service and number services. This includes...

  15. 46 CFR 272.14 - Survey procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Survey procedures. 272.14 Section 272.14 Shipping... OPERATORS REQUIREMENTS AND PROCEDURES FOR CONDUCTING CONDITION SURVEYS AND ADMINISTERING MAINTENANCE AND... Survey procedures. (a) Prior to survey. Unless otherwise directed by MARAD, the Operator of a vessel...

  16. 46 CFR 272.14 - Survey procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Survey procedures. 272.14 Section 272.14 Shipping... OPERATORS REQUIREMENTS AND PROCEDURES FOR CONDUCTING CONDITION SURVEYS AND ADMINISTERING MAINTENANCE AND... Survey procedures. (a) Prior to survey. Unless otherwise directed by MARAD, the Operator of a vessel...

  17. 46 CFR 272.14 - Survey procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Survey procedures. 272.14 Section 272.14 Shipping... OPERATORS REQUIREMENTS AND PROCEDURES FOR CONDUCTING CONDITION SURVEYS AND ADMINISTERING MAINTENANCE AND... Survey procedures. (a) Prior to survey. Unless otherwise directed by MARAD, the Operator of a vessel...

  18. 46 CFR 272.14 - Survey procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Survey procedures. 272.14 Section 272.14 Shipping... OPERATORS REQUIREMENTS AND PROCEDURES FOR CONDUCTING CONDITION SURVEYS AND ADMINISTERING MAINTENANCE AND... Survey procedures. (a) Prior to survey. Unless otherwise directed by MARAD, the Operator of a vessel...

  19. 46 CFR 272.14 - Survey procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Survey procedures. 272.14 Section 272.14 Shipping... OPERATORS REQUIREMENTS AND PROCEDURES FOR CONDUCTING CONDITION SURVEYS AND ADMINISTERING MAINTENANCE AND... Survey procedures. (a) Prior to survey. Unless otherwise directed by MARAD, the Operator of a vessel...

  20. 14 CFR 93.309 - General operating procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false General operating procedures. 93.309... Vicinity of Grand Canyon National Park, AZ § 93.309 General operating procedures. Except in an emergency... authorized in writing by the Flight Standards District Office: (1) Northbound. 11,500 or 13,500 feet MSL. (2...

  1. 14 CFR 93.309 - General operating procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false General operating procedures. 93.309... Vicinity of Grand Canyon National Park, AZ § 93.309 General operating procedures. Except in an emergency... authorized in writing by the Flight Standards District Office: (1) Northbound. 11,500 or 13,500 feet MSL. (2...

  2. 14 CFR 93.309 - General operating procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false General operating procedures. 93.309... Vicinity of Grand Canyon National Park, AZ § 93.309 General operating procedures. Except in an emergency... authorized in writing by the Flight Standards District Office: (1) Northbound. 11,500 or 13,500 feet MSL. (2...

  3. 14 CFR 93.309 - General operating procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false General operating procedures. 93.309... Vicinity of Grand Canyon National Park, AZ § 93.309 General operating procedures. Except in an emergency... authorized in writing by the Flight Standards District Office: (1) Northbound. 11,500 or 13,500 feet MSL. (2...

  4. 14 CFR 93.309 - General operating procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false General operating procedures. 93.309... Vicinity of Grand Canyon National Park, AZ § 93.309 General operating procedures. Except in an emergency... authorized in writing by the Flight Standards District Office: (1) Northbound. 11,500 or 13,500 feet MSL. (2...

  5. NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR CALIBRATION, MAINTENANCE AND OPERATION OF ELECTRONIC BALANCES (BCO-L-23.0)

    EPA Science Inventory

    The purpose of this SOP is to describe the general procedures to be followed for the operation, calibration and maintenance of electronic balances. This procedure was followed to ensure consistent data retrieval during the Arizona NHEXAS project and the "Border" study. Keywords: ...

  6. 5 CFR 9701.406 - Setting and communicating performance expectations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... apply to all employees, such as standard operating procedures, handbooks, or other operating... organizational level; (2) Organizational, occupational, or other work requirements, such as standard operating procedures, operating instructions, administrative manuals, internal rules and directives, and/or other...

  7. 5 CFR 9701.406 - Setting and communicating performance expectations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... apply to all employees, such as standard operating procedures, handbooks, or other operating... organizational level; (2) Organizational, occupational, or other work requirements, such as standard operating procedures, operating instructions, administrative manuals, internal rules and directives, and/or other...

  8. 5 CFR 9701.406 - Setting and communicating performance expectations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... apply to all employees, such as standard operating procedures, handbooks, or other operating... organizational level; (2) Organizational, occupational, or other work requirements, such as standard operating procedures, operating instructions, administrative manuals, internal rules and directives, and/or other...

  9. 5 CFR 9701.406 - Setting and communicating performance expectations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... apply to all employees, such as standard operating procedures, handbooks, or other operating... organizational level; (2) Organizational, occupational, or other work requirements, such as standard operating procedures, operating instructions, administrative manuals, internal rules and directives, and/or other...

  10. 40 CFR 240.200-3 - Recommended procedures: Operations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-3 Recommended procedures: Operations. (a) Storage areas for special wastes should be... acceptance of Special Wastes. ...

  11. 40 CFR 240.200-3 - Recommended procedures: Operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.200-3 Recommended procedures: Operations. (a) Storage areas for special wastes should be... acceptance of Special Wastes. ...

  12. What is the safety of nonemergent operative procedures performed at night? A study of 10,426 operations at an academic tertiary care hospital using the American College of Surgeons national surgical quality program improvement database.

    PubMed

    Turrentine, Florence E; Wang, Hongkun; Young, Jeffrey S; Calland, James Forrest

    2010-08-01

    Ever-increasing numbers of in-house acute care surgeons and competition for operating room time during normal daytime business hours have led to an increased frequency of nonemergent general and vascular surgery procedures occurring at night when there are fewer residents, consultants, nurses, and support staff available for assistance. This investigation tests the hypothesis that patients undergoing such procedures after hours are at increased risk for postoperative morbidity and mortality. Clinical data for 10,426 operative procedures performed over a 5-year period at a single academic tertiary care hospital were obtained from the American College of Surgeons National Surgical Quality Improvement Program Database. The prevalence of preoperative comorbid conditions, postoperative length of stay, morbidity, and mortality was compared between two cohorts of patients: one who underwent nonemergent operative procedures at night and other who underwent similar procedures during the day. Subsequent statistical comparisons utilized chi tests for comparisons of categorical variables and F-tests for continuous variables. Patients undergoing procedures at night had a greater prevalence of serious preoperative comorbid conditions. Procedure complexity as measured by relative value unit did not differ between groups, but length of stay was longer after night procedures (7.8 days vs. 4.3 days, p < 0.0001). Patients undergoing nonemergent general and vascular surgery procedures at night in an academic medical center do not seem to be at increased risk for postoperative morbidity or mortality. Performing nonemergent procedures at night seems to be a safe solution for daytime overcrowding of operating rooms.

  13. Decreased glutathione levels predict loss of brain volume in children and adolescents with first-episode psychosis in a two-year longitudinal study.

    PubMed

    Fraguas, David; Gonzalez-Pinto, Ana; Micó, Juan Antonio; Reig, Santiago; Parellada, Mara; Martínez-Cengotitabengoa, Mónica; Castro-Fornieles, Josefina; Rapado-Castro, Marta; Baeza, Immaculada; Janssen, Joost; Desco, Manuel; Leza, Juan Carlos; Arango, Celso

    2012-05-01

    Progressive loss of cortical gray matter (GM), as measured by magnetic resonance imaging, has been described early in the course of first-episode psychosis. This study aims to assess the relationship between oxidative balance and progression of cortical GM changes in a multicenter sample of first-episode early-onset psychosis (EOP) patients from baseline to two-year follow-up. A total of 48 patients (13 females, mean age 15.9±1.5 years) and 56 age- and gender-matched healthy controls (19 females, 15.3±1.5 years) were assessed. Magnetic resonance imaging (MRI) scans performed both at the time of the first psychotic episode and 2 years later were used for volumetric measurements of left and right gray matter regions (frontal, parietal, and temporal lobes) and total sulcal cerebrospinal fluid (CSF). Total glutathione (GSH) blood levels were determined at baseline. In patients, after controlling for possible confounding variables, lower baseline GSH levels were significantly associated with greater volume decrease in left frontal (B=0.034, 95% confidence interval (CI): 0.011 to 0.056, r=0.620, p=0.006), parietal (B=0.039, 95% CI: 0.020 to 0.059, r=0.739, p=0.001), temporal (B=0.026, 95% CI: 0.016 to 0.036, r=0.779, p<0.001), and total (B=0.022, 95% CI: 0.014 to 0.031, r=0.803, p<0.001) gray matter, and with greater increase in total CSF (B=-0.560, 95% CI: -0.270 to -0.850, r=-0.722, p=0.001). Controls did not show significant associations between brain volume changes and GSH levels. GSH deficit during the first psychotic episode was related to greater loss of cortical GM two years later in patients with first-episode EOP, suggesting that oxidative damage may contribute to the progressive loss of cortical GM found in patients with first-episode psychosis. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. Towards a Refined Realisation of the Terrestrial Reference System

    NASA Astrophysics Data System (ADS)

    Angermann, D.; Drewes, H.; Meisel, B.; Kruegel, M.; Tesmer, V.

    2004-12-01

    Global reference frames provide the framework for scientific investigations of the Earth's system (e.g. plate tectonics, sea level change, seasonal and secular loading signals, atmosphere dynamics, Earth orientation excitation), as well as for many practical applications (e.g. surveying and navigation). Today, space geodetic techniques allow to determine geodetic parameters (e.g. station positions, Earth rotation) with a precision of a few millimeters (or even better). However, this high accuracy is not reflected by current realisations of the terrestrial reference system. To fully exploit the potential of the space geodetic observations for investigations of various global and regional, short-term, seasonal and secular phenomena of the Earth's system, the reference frame must be realised with the highest accuracy, spatial and temporal consistency and stability over decades. Furthermore, future progress in Earth sciences will fundamentally depend on understanding the Earth as a system, into which the three areas of geodetic research (geometry/deformation, Earth rotation, gravity) are to be integrated. The presentation focusses on various aspects that must be considered for a refined realisation of the terrestrial reference system, such as the development of suitable methods for the combination of the contributing space geodetic observations, the realisation of the TRF datum and the parameterisation of site motions. For this purpose we investigated time series of station positions and datum parameters obtained from VLBI, SLR, GPS and DORIS solutions, and compared the results at co-location sites and with other studies. Furthermore, we present results obtained from a TRS realisation based on epoch (weekly/daily) normal equations with station positions and daily Earth Orientation Parameters (EOP) using five years (1999-2004) of VLBI, SLR, GPS and DORIS data. This refined approach has major advantages compared to past TRF realisations based on multi-year solutions with station positions at a given epoch and constant velocities, as for instance non-linear effects of site positions and datum parameters can be considered, and consistency between TRF and EOPs can be achieved. First results of this new approach are promising.

  15. Commentary: 'Unhealthy diet,' nutrient status, and ADHD symptoms: a confounding role for environmental nitrous oxide exposure - reflections on Rijlaarsdam et al. (2016).

    PubMed

    Fluegge, Keith

    2017-01-01

    Rijlaarsdam et al. (2016) recently published their findings utilizing a longitudinal design showing that prenatal 'unhealthy diet' was positively associated with IGF2 DNA methylation at birth across both youth cohorts. However, only in the EOP youth was prenatal 'unhealthy diet' positively associated with ADHD symptoms presumably through IGF2 DNA hypermethylation. Rijlaarsdam et al.'s () choice to assess high fat and sugar diet with the Food Frequency Questionnaire (FFQ) may offer some indication as to prenatal nutrient status, as the foods identified by the FFQ in their study are relatively low in free choline. It has been shown that gestational choline deficiency in rats leads to hypermethylation of IGF2. Consistent with the literature describing an association between air pollution and cognitive neurodevelopmental impairment, the author of this commentary has previously proposed through empirical investigation that chronic environmental exposure to the trace levels of the pervasive air pollutant, nitrous oxide (N 2 O), may facilitate core features of neurodevelopmental disorders, like ADHD. Impaired acetylcholine synthesis in rats exposed to N 2 O has been shown, with a 53% reduction in [1-2H2,2-2H2] choline. Low-dose N 2 O exposure is also thought to stimulate central release of opioid peptides, like dynorphin, which play a role in significantly increasing food intake behavior and/or modulating sucrose intake. Taken altogether, these studies present a strong confounder to the interpretation made by Rijlaarsdam et al. () that prenatal 'unhealthy diet' may play a role in the onset of ADHD symptoms in youth with EOP conduct problems through induction of IGF2 DNA hypermethylation. While the 'unhealthy diet' may represent possible maternal nutrient deficiencies during gestation, it is also possible that exposure to air pollutants, particularly N 2 O, may not only directly reduce fetal cholinergic status thereby enhancing IGF2 DNA hypermethylation but may also significantly modulate maternal food intake behaviors (i.e. sucrose). © 2016 Association for Child and Adolescent Mental Health.

  16. Kernel and System Procedures in Flex.

    DTIC Science & Technology

    1983-08-01

    System procedures on which the operating system for the Flex computer is based. These are the low level rOCedures Whbich are used to implement the compilers, file-store* coummand interpreters etc on Flex. 168 ... System procedures on which the operating system for the Flex computer is based. These are the low level procedures which are used to implement the...privileged mode. They form the interface between the user and a particular operating system written on top of the Kernel.

  17. 12 CFR 1271.33 - Book-entry procedure for Financing Corporation obligations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Book-entry procedure for Financing Corporation... MISCELLANEOUS FEDERAL HOME LOAN BANK OPERATIONS AND AUTHORITIES Financing Corporation Operations § 1271.33 Book... have authority to apply book-entry procedure to Financing Corporation obligations. (b) Procedure. The...

  18. U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION AND INITIALIZATION OF THE MAGELLAN GPS SATELLITE NAVIGATOR (UA-F-22.1)

    EPA Science Inventory

    The purpose of this SOP is to describe the general procedures for the operation and initialization of the Magellan Global Positioning System (GPS) Satellite Navigator. This procedure was followed to ensure consistent data retrieval during the Arizona NHEXAS project and the Borde...

  19. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  20. 76 FR 49286 - Third Party Testing for Certain Children's Products; Notice of Requirements for Accreditation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... tested in accordance with CPSC-CH-C1001-09.3, Standard Operating Procedure for Determination of...-C1001-09.3, Standard Operating Procedure for Determination of Phthalates, issued on April 1, 2010...-C1001-09.3, Standard Operating Procedure for Determination of Phthalates, and GB/T 22048-2008, Toys and...

  1. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  2. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  3. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  4. 9 CFR 354.210 - Minimum standards for sanitation, facilities, and operating procedures in official plants.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Minimum standards for sanitation, facilities, and operating procedures in official plants. 354.210 Section 354.210 Animals and Animal Products... sanitation, facilities, and operating procedures in official plants. The provisions of §§ 354.210 to 354.247...

  5. NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION, CALIBRATION AND MAINTENANCE OF FIXED AND ADJUSTABLE VOLUME PIPETTE GUNS (BCO-L-9.0)

    EPA Science Inventory

    The purpose of this SOP is to describe the general procedures for the operation, calibration, and maintenance of fixed- and adjustable-volume pipette guns. This procedure was followed to ensure consistent data retrieval during the Arizona NHEXAS project and the "Border" study. Ke...

  6. NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION AND INITIALIZATION OF THE MAGELLAN GPS SATELLITE NAVIGATOR (UA-F-22.1)

    EPA Science Inventory

    The purpose of this SOP is to describe the general procedures for the operation and initialization of the Magellan Global Positioning System (GPS) Satellite Navigator. This procedure was followed to ensure consistent data retrieval during the Arizona NHEXAS project and the "Bord...

  7. OCCUPATIONAL RADIATION DOSES TO OPERATORS PERFORMING FLUOROSCOPICALLY-GUIDED PROCEDURES

    PubMed Central

    Kim, Kwang Pyo; Miller, Donald L.; de Gonzalez, Amy Berrington; Balter, Stephen; Kleinerman, Ruth A.; Ostroumova, Evgenia; Simon, Steven L.; Linet, Martha S.

    2012-01-01

    In the past 30 years, the numbers and types of fluoroscopically-guided (FG) procedures have increased dramatically. The objective of the present study is to provide estimated radiation doses to physician specialists, other than cardiologists, who perform FG procedures. We searched Medline to identify English-language journal articles reporting radiation exposures to these physicians. We then identified several primarily therapeutic FG procedures that met specific criteria: well-defined procedures for which there were at least five published reports of estimated radiation doses to the operator, procedures performed frequently in current medical practice, and inclusion of physicians from multiple medical specialties. These procedures were percutaneous nephrolithotomy (PCNL), vertebroplasty, orthopedic extremity nailing for treatment of fractures, biliary tract procedures, transjugular intrahepatic portosystemic shunt creation (TIPS), head/neck endovascular therapeutic procedures, and endoscopic retrograde cholangiopancreatography (ERCP). We abstracted radiation doses and other associated data, and estimated effective dose to operators. Operators received estimated doses per patient procedure equivalent to doses received by interventional cardiologists. The estimated effective dose per case ranged from 1.7 – 56μSv for PCNL, 0.1 – 101 μSv for vertebroplasty, 2.5 – 88μSv for orthopedic extremity nailing, 2.0 – 46μSv for biliary tract procedures, 2.5 – 74μSv for TIPS, 1.8 – 53μSv for head/neck endovascular therapeutic procedures, and 0.2 – 49μSv for ERCP. Overall, mean operator radiation dose per case measured over personal protective devices at different anatomic sites on the head and body ranged from 19 – 800 (median = 113) μSv at eye level, 6 – 1180 (median = 75)μSv at the neck, and 2 – 1600 (median = 302) μSv at the trunk. Operators’ hands often received greater doses than the eyes, neck or trunk. Large variations in operator doses suggest that optimizing procedure protocols and proper use of protective devices and shields might reduce occupational radiation dose substantially. PMID:22647920

  8. Surgeon specialization and operative mortality in United States: retrospective analysis

    PubMed Central

    Dalton, Maurice; Cutler, David M; Birkmeyer, John D; Chandra, Amitabh

    2016-01-01

    Objective To measure the association between a surgeon’s degree of specialization in a specific procedure and patient mortality. Design Retrospective analysis of Medicare data. Setting US patients aged 66 or older enrolled in traditional fee for service Medicare. Participants 25 152 US surgeons who performed one of eight procedures (carotid endarterectomy, coronary artery bypass grafting, valve replacement, abdominal aortic aneurysm repair, lung resection, cystectomy, pancreatic resection, or esophagectomy) on 695 987 patients in 2008-13. Main outcome measure Relative risk reduction in risk adjusted and volume adjusted 30 day operative mortality between surgeons in the bottom quarter and top quarter of surgeon specialization (defined as the number of times the surgeon performed the specific procedure divided by his/her total operative volume across all procedures). Results For all four cardiovascular procedures and two out of four cancer resections, a surgeon’s degree of specialization was a significant predictor of operative mortality independent of the number of times he or she performed that procedure: carotid endarterectomy (relative risk reduction between bottom and top quarter of surgeons 28%, 95% confidence interval 0% to 48%); coronary artery bypass grafting (15%, 4% to 25%); valve replacement (46%, 37% to 53%); abdominal aortic aneurysm repair (42%, 29% to 53%); lung resection (28%, 5% to 46%); and cystectomy (41%, 8% to 63%). In five procedures (carotid endarterectomy, valve replacement, lung resection, cystectomy, and esophagectomy), the relative risk reduction from surgeon specialization was greater than that from surgeon volume for that specific procedure. Furthermore, surgeon specialization accounted for 9% (coronary artery bypass grafting) to 100% (cystectomy) of the relative risk reduction otherwise attributable to volume in that specific procedure. Conclusion For several common procedures, surgeon specialization was an important predictor of operative mortality independent of volume in that specific procedure. When selecting a surgeon, patients, referring physicians, and administrators assigning operative workload may want to consider a surgeon’s procedure specific volume as well as the degree to which a surgeon specializes in that procedure. PMID:27444190

  9. Impact of the 80-hour work week on resident emergency operative experience.

    PubMed

    Feanny, Mark A; Scott, Bradford G; Mattox, Kenneth L; Hirshberg, Asher

    2005-12-01

    The goal of this study was to analyze the impact of the 80-hour work week on the emergency operative experience of surgical residents. A 2-year retrospective comparison of the operative experience in emergency abdominal procedures of postgraduate year 4 and 5 residents in a city hospital before (group 1) and after (group 2) duty hour restriction. There was no difference between groups in the mean number of procedures performed as the primary surgeon, but group 2 showed a 40% decrease in technically advanced procedures with a 44% increase in basic procedures. The study also demonstrated a 54% decrease in the operative volume as first assistant. Operative continuity of care by residents decreased from 60% to 26% of cases. The ACGME regulatory environment is adversely affecting the emergency operative experience of surgical residents. Our findings underscore the need to develop alternative methods to augment the residents' operative experience.

  10. Operative experience of residents in US general surgery programs: a gap between expectation and experience.

    PubMed

    Bell, Richard H; Biester, Thomas W; Tabuenca, Arnold; Rhodes, Robert S; Cofer, Joseph B; Britt, L D; Lewis, Frank R

    2009-05-01

    The purpose of the study was to identify a group of operations which general surgery residency program directors believed residents should be competent to perform by the end of 5 years of training and then ascertain actual resident experience with these procedures during their training. There is concern about the adequacy of training of general surgeons in the United States. The American Board of Surgery and the Association of Program Directors in Surgery undertook a study to determine what operative procedures residency program directors consider to be essential to the practice of general surgery and then we measured the actual operative experience of graduating residents in those procedures, as reported to the Residency Review Committee for Surgery (RRC). An electronic survey was sent to residency program directors at the 254 general surgery programs in the US accredited by the RRC as of spring 2006. The program directors were presented with a list of 300 types of operations. Program directors graded the 300 procedures "A," "B," or "C" using the following criteria: A--graduating general surgery residents should be competent to perform the procedure independently; B--graduating residents should be familiar with the procedure, but not necessarily competent to perform it; and C--graduating residents neither need to be familiar with nor competent to perform the procedure. After ballots were tallied, the actual resident operative experience reported to the RRC by all residents finishing general surgery training in June 2005 was reviewed. One hundred twenty-one of the 300 operations were considered A level procedures by a majority of program directors (PDs). Graduating 2005 US residents (n = 1022) performed only 18 of the 121 A procedures, an average of more than 10 times during residency; 83 of 121 procedures were performed on an average less than 5 times and 31 procedures less than once. For 63 of the 121 procedures, the mode (most commonly reported) experience was 0. In addition, there was significant variation between residents in operative experience for specific procedures. In virtually all cases, the mean reported experience exceeded the mode, suggesting that the mean is a poor measure of typical experience. These data pose important problems for surgical educators. Methods will have to be developed to allow surgeons to reach a basic level of competence in procedures which they are likely to experience only rarely during residency. Even for more commonly performed procedures, the numbers of repetitions are not very robust, stressing the need to determine objectively whether residents are actually achieving basic competency in these operations. Finally, the large variations in experience between individuals in our residency system need to be explored, understood, and remedied.

  11. Towards Verification of Operational Procedures Using Auto-Generated Diagnostic Trees

    NASA Technical Reports Server (NTRS)

    Kurtoglu, Tolga; Lutz, Robyn; Patterson-Hine, Ann

    2009-01-01

    The design, development, and operation of complex space, lunar and planetary exploration systems require the development of general procedures that describe a detailed set of instructions capturing how mission tasks are performed. For both crewed and uncrewed NASA systems, mission safety and the accomplishment of the scientific mission objectives are highly dependent on the correctness of procedures. In this paper, we describe how to use the auto-generated diagnostic trees from existing diagnostic models to improve the verification of standard operating procedures. Specifically, we introduce a systematic method, namely the Diagnostic Tree for Verification (DTV), developed with the goal of leveraging the information contained within auto-generated diagnostic trees in order to check the correctness of procedures, to streamline the procedures in terms of reducing the number of steps or use of resources in them, and to propose alternative procedural steps adaptive to changing operational conditions. The application of the DTV method to a spacecraft electrical power system shows the feasibility of the approach and its range of capabilities

  12. Human factors research plan for instrument procedures : FY12 version 1.1

    DOT National Transportation Integrated Search

    2012-06-19

    This research will support the development of instrument procedures for performance-based navigation (PBN) operations. These procedures include, but are not limited to, area navigation (RNAV) and required navigation performance (RNP) operations. The ...

  13. U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION, CALIBRATION AND MAINTENANCE OF FIXED AND ADJUSTABLE VOLUME PIPETTE GUNS (BCO-L-9.0)

    EPA Science Inventory

    The purpose of this SOP is to describe the general procedures for the operation, calibration, and maintenance of fixed- and adjustable-volume pipette guns. This procedure was followed to ensure consistent data retrieval during the Arizona NHEXAS project and the Border study. Keyw...

  14. A Guide for Developing Standard Operating Job Procedures for the Tertiary Chemical Treatment - Lime Precipitation Process Wastewater Treatment Facility. SOJP No. 6.

    ERIC Educational Resources Information Center

    Petrasek, Al, Jr.

    This guide describes the standard operating job procedures for the tertiary chemical treatment - lime precipitation process of wastewater treatment plants. Step-by-step instructions are given for pre-start up, start-up, continuous operation, and shut-down procedures. In addition, some theoretical material is presented along with some relevant…

  15. A Guide for Developing Standard Operating Job Procedures for the Grit Removal Process Wastewater Treatment Facility. SOJP No. 2.

    ERIC Educational Resources Information Center

    Deal, Gerald A.; Montgomery, James A.

    This guide describes standard operating job procedures for the grit removal process of wastewater treatment plants. Step-by-step instructions are given for pre-start up inspection, start-up, continuous operation, and shut-down procedures. A description of the equipment used in the process is given. Some theoretical material is presented. (BB)

  16. NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION, CALIBRATION AND ROUTINE USE OF THE SPECTRACE 9000 FIELD PORTABLE X-RAY FLUORESCENCE ANALYZER (UA-L-10.1)

    EPA Science Inventory

    The purpose of this SOP is to describe the procedures for operating and calibrating the Spectrace 9000 field portable X-ray fluorescence analyzer. This procedure applies to the determination of metal concentrations in samples during the Arizona NHEXAS project and the "Border" st...

  17. NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION, CALIBRATION AND MAINTENANCE OF THE PERKIN-ELMER 1100B ATOMIC ABSORPTION SPECTROMETER (BCO-L-5.1)

    EPA Science Inventory

    The purpose of this SOP is to outline the start-up, calibration, operation, and maintenance procedures for the Perkin-Elmer 5100 PC Atomic Absorption Spectrophotometer (PE 5100). These procedures are used for the determination of the target trace metal, as in soil, house dust, f...

  18. [A project to improve the validity rate for nursing staff operating single door autoclave sterilizers].

    PubMed

    Chen, Chun-Hung; Li, Cheng-Chang; Chou, Chuan-Yu; Chen, Shu-Hwa

    2009-08-01

    This project was designed to improve the low validity rate for nurses responsible to operate single door autoclave sterilizers in the operating room. By investigating the current status, we found that the nursing staff validity rate of cognition on the autoclave sterilizer was 85%, and the practice operating check validity rate was only 80%. Such was due to a lack of in-service education. Problems with operation included: 1. Unsafe behaviors - not following standard procedure, lacking relevant operating knowledge and absence of a check form; 2. Unsafe environment - the conveying steam piping was typically not covered and lacked operation marks. Recommended improvement measures included: 1. holding in-service education; 2. generating an operation procedure flow chart; 3. implementing obstacle eliminating procedures; 4. covering piping to prevent fire and burns; 5. performing regular checks to ensure all procedures are followed. Following intervention, nursing staff cognition rose from 85% to 100%, while the operation validity rate rose from 80% to 100%. These changes ensure a safer operating room environment, and helps facilities move toward a zero accident rate in the healthcare environment.

  19. Ultra-rapid EOP determination with VLBI

    NASA Astrophysics Data System (ADS)

    Haas, Rüdiger; Kurihara, Shinobu; Nozawa, Kentaro; Hobiger, Thomas; Lovell, Jim; McCallum, Jamie; Quick, Jonathan

    2013-04-01

    In 2007 the Geospatial information Authority of Japan (GSI) and the Onsala Space Observatory (OSO) started a project aiming at determining the earth rotation angle, usually expressed as dUT1, in near real-time. In the beginning of this project dedicated one hour long one-baseline experiments were observed periodically using the VLBI stations Onsala (Sweden) and Tsukuba (Japan). The strategy is that the observed VLBI-data are sent in real-time via the international optical fibre backbone to the VLBI-correlator at Tsukuba where the data are correlated and analyzed in near-real time, producing ultra-rapid dUT1 results. An offline version of this strategy has been adopted in 2009 for the regular VLBI intensive series INT-2 involving Wettzell (Germany) and Tsukuba. Since March 2010 the INT-2 is using real-time e-transfer, too, and since June 2010 also automated analysis. Starting in 2009 the ultra-rapid approach was applied to regular 24 hour long VLBI-sessions that involve Tsukuba and Onsala, so that ultra-rapid dUT1 results can be produced already during ongoing VLBI-sessions. This strategy was successfully operated during the 15 days long CONT11 campaign. In 2011 the ultra-rapid strategy was extended to involve a network of VLBI-stations, so that not only dUT1 but also the polar motion components can be determined in near real-time. Initially, in November 2011 a dedicated three-station session was observed involving Onsala, Tsukuba and Hobart (Tasmania, Australia). In 2012 several regular 24 hour long IVS-sessions that involved Onsala, Tsukuba and HartRAO (South Africa) were operated with the ultra-rapid strategy, and in several cases also Hobart was added as a fourth station. For this project we use the new analysis software c5++ developed by the National Institute of Information and Communications Technology (NICT). In this presentation we give an overview of the UREOP-project, describe the recent developments, and discuss the obtained results.

  20. 40 CFR 264.1201 - Design and operating standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Design and operating standards. 264... FACILITIES Hazardous Waste Munitions and Explosives Storage § 264.1201 Design and operating standards. (a... Operating Procedure specifying procedures to ensure safety, security, and environmental protection. If these...

  1. 40 CFR 264.1201 - Design and operating standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Design and operating standards. 264... FACILITIES Hazardous Waste Munitions and Explosives Storage § 264.1201 Design and operating standards. (a... Operating Procedure specifying procedures to ensure safety, security, and environmental protection. If these...

  2. 40 CFR 264.1201 - Design and operating standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Design and operating standards. 264... FACILITIES Hazardous Waste Munitions and Explosives Storage § 264.1201 Design and operating standards. (a... Operating Procedure specifying procedures to ensure safety, security, and environmental protection. If these...

  3. 40 CFR 265.1201 - Design and operating standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... be stored in accordance with a Standard Operating Procedure specifying procedures to ensure safety... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Design and operating standards. 265... operating standards. (a) Hazardous waste munitions and explosives storage units must be designed and...

  4. 40 CFR 265.1201 - Design and operating standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... be stored in accordance with a Standard Operating Procedure specifying procedures to ensure safety... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Design and operating standards. 265... operating standards. (a) Hazardous waste munitions and explosives storage units must be designed and...

  5. 40 CFR 265.1201 - Design and operating standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... be stored in accordance with a Standard Operating Procedure specifying procedures to ensure safety... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Design and operating standards. 265... operating standards. (a) Hazardous waste munitions and explosives storage units must be designed and...

  6. 40 CFR 265.1201 - Design and operating standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... be stored in accordance with a Standard Operating Procedure specifying procedures to ensure safety... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Design and operating standards. 265... operating standards. (a) Hazardous waste munitions and explosives storage units must be designed and...

  7. 40 CFR 264.1201 - Design and operating standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Design and operating standards. 264... FACILITIES Hazardous Waste Munitions and Explosives Storage § 264.1201 Design and operating standards. (a... Operating Procedure specifying procedures to ensure safety, security, and environmental protection. If these...

  8. Situation awareness and trust in computer-based procedures in nuclear power plant operations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Throneburg, E. B.; Jones, J. M.

    2006-07-01

    Situation awareness and trust are two issues that need to be addressed in the design of computer-based procedures for nuclear power plants. Situation awareness, in relation to computer-based procedures, concerns the operators' knowledge of the plant's state while following the procedures. Trust concerns the amount of faith that the operators put into the automated procedures, which can affect situation awareness. This paper first discusses the advantages and disadvantages of computer-based procedures. It then discusses the known aspects of situation awareness and trust as applied to computer-based procedures in nuclear power plants. An outline of a proposed experiment is then presentedmore » that includes methods of measuring situation awareness and trust so that these aspects can be analyzed for further study. (authors)« less

  9. Ultrashort-Pulse Laser System: Theory of Operation and Operating Procedures

    DTIC Science & Technology

    1992-07-01

    Nov 89 - Jul 92 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS Ultrashort-Pulse Laser System : Theory of Operation and C - F33615-88-C-0631 Operating...i ’IR~A&, D2;" T.&B [E] al uicod [] j 0 Avhi lp.bilty C: oded’ Avail i Qiv ULTRASHORT-PULSE LASER SYSTEM : THEORY OF OPERATION AND OPERATING PROCEDURES

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ryan, E. Ronan, E-mail: ronan@ronanryan.com; Thornton, Raymond; Sofocleous, Constantinos T.

    PurposeTo quantify radiation exposure to the primary operator and staff during PET/CT-guided interventional procedures.MethodsIn this prospective study, 12 patients underwent PET/CT-guided interventions over a 6 month period. Radiation exposure was measured for the primary operator, the radiology technologist, and the nurse anesthetist by means of optically stimulated luminescence dosimeters. Radiation exposure was correlated with the procedure time and the use of in-room image guidance (CT fluoroscopy or ultrasound).ResultsThe median effective dose was 0.02 (range 0-0.13) mSv for the primary operator, 0.01 (range 0-0.05) mSv for the nurse anesthetist, and 0.02 (range 0-0.05) mSv for the radiology technologist. The median extremitymore » dose equivalent for the operator was 0.05 (range 0-0.62) mSv. Radiation exposure correlated with procedure duration and with the use of in-room image guidance. The median operator effective dose for the procedure was 0.015 mSv when conventional biopsy mode CT was used, compared to 0.06 mSv for in-room image guidance, although this did not achieve statistical significance as a result of the small sample size (p = 0.06).ConclusionThe operator dose from PET/CT-guided procedures is not significantly different than typical doses from fluoroscopically guided procedures. The major determinant of radiation exposure to the operator from PET/CT-guided interventional procedures is time spent in close proximity to the patient.« less

  11. Economics of BAQ (Basic Allowance for Quarters)/Rent-Plus versus Government Leasing (USAREUR Family Housing)

    DTIC Science & Technology

    1985-05-01

    o> \\T\\ -a* PH CM *• • • » mm m ^ ?. en s 00 «H *J ■■* vO *M « «H CM lA CM 3ii X sg« ■X* g > • u C %• • S3 55 O m «m ’ 6...125,063 146,080 271,143 55 4,930 04-05 6 W4 11,656 5,312 16,968 2 8,484 Goepplngen EI-B3** 0 0 0 0 0 E4-E6 531,860 466,360 998,220 178 5,608 E7-E9...prograaa would ba dapraaaad by aa epelalsele individual rnatal forecast. (ESC). d. Chare 19: VCSA seated ehae eh« eop; Una la ooe eh« Mr« qolc «aajie,M but

  12. New image-processing and noise-reduction software reduces radiation dose during complex endovascular procedures.

    PubMed

    Kirkwood, Melissa L; Guild, Jeffrey B; Arbique, Gary M; Tsai, Shirling; Modrall, J Gregory; Anderson, Jon A; Rectenwald, John; Timaran, Carlos

    2016-11-01

    A new proprietary image-processing system known as AlluraClarity, developed by Philips Healthcare (Best, The Netherlands) for radiation-based interventional procedures, claims to lower radiation dose while preserving image quality using noise-reduction algorithms. This study determined whether the surgeon and patient radiation dose during complex endovascular procedures (CEPs) is decreased after the implementation of this new operating system. Radiation dose to operators, procedure type, reference air kerma, kerma area product, and patient body mass index were recorded during CEPs on two Philips Allura FD 20 fluoroscopy systems with and without Clarity. Operator dose during CEPs was measured using optically stimulable, luminescent nanoDot (Landauer Inc, Glenwood, Ill) detectors placed outside the lead apron at the left upper chest position. nanoDots were read using a microStar ii (Landauer Inc) medical dosimetry system. For the CEPs in the Clarity group, the radiation dose to surgeons was also measured by the DoseAware (Philips Healthcare) personal dosimetry system. Side-by-side measurements of DoseAware and nanoDots allowed for cross-calibration between systems. Operator effective dose was determined using a modified Niklason algorithm. To control for patient size and case complexity, the average fluoroscopy dose rate and the dose per radiographic frame were adjusted for body mass index differences and then compared between the groups with and without Clarity by procedure. Additional factors, for example, physician practice patterns, that may have affected operator dose were inferred by comparing the ratio of the operator dose to procedural kerma area product with and without Clarity. A one-sided Wilcoxon rank sum test was used to compare groups for radiation doses, reference air kermas, and operating practices for each procedure type. The analysis included 234 CEPs; 95 performed without Clarity and 139 with Clarity. Practice patterns of operators during procedures with and without Clarity were not significantly different. For all cases, procedure radiation dose to the patient and the primary and assistant operators were significantly decreased in the Clarity group by 60% compared with the non-Clarity group. By procedure type, fluorography dose rates decreased from 44% for fenestrated endovascular repair and up to 70% with lower extremity interventions. Fluoroscopy dose rates also significantly decreased, from about 37% to 47%, depending on procedure type. The AlluraClarity system reduces the patient and primary operator's radiation dose by more than half during CEPs. This feature appears to be an effective tool in lowering the radiation dose while maintaining image quality. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

  13. Lageos assembly operation plan

    NASA Technical Reports Server (NTRS)

    Brueger, J.

    1975-01-01

    Guidelines and constraints procedures for LAGEOS assembly, operation, and design performance are given. Special attention was given to thermal, optical, and dynamic analysis and testing. The operation procedures illustrate the interrelation and sequence of tasks in a flow diagram. The diagram also includes quality assurance functions for verification of operation tasks.

  14. Use of National Burden to Define Operative Emergency General Surgery.

    PubMed

    Scott, John W; Olufajo, Olubode A; Brat, Gabriel A; Rose, John A; Zogg, Cheryl K; Haider, Adil H; Salim, Ali; Havens, Joaquim M

    2016-06-15

    Emergency general surgery (EGS) represents 11% of surgical admissions and 50% of surgical mortality in the United States. However, there is currently no established definition of the EGS procedures. To define a set of procedures accounting for at least 80% of the national burden of operative EGS. A retrospective review was conducted using data from the 2008-2011 National Inpatient Sample. Adults (age, ≥18 years) with primary EGS diagnoses consistent with the American Association for the Surgery of Trauma definition, admitted urgently or emergently, who underwent an operative procedure within 2 days of admission were included in the analyses. Procedures were ranked to account for national mortality and complication burden. Among ranked procedures, contributions to total EGS frequency, mortality, and hospital costs were assessed. The data query and analysis were performed between November 15, 2015, and February 16, 2016. Overall procedure frequency, in-hospital mortality, major complications, and inpatient costs calculated per 3-digit International Classification of Diseases, Ninth Revision, Clinical Modification procedure codes. The study identified 421 476 patient encounters associated with operative EGS, weighted to represent 2.1 million nationally over the 4-year study period. The overall mortality rate was 1.23% (95% CI, 1.18%-1.28%), the complication rate was 15.0% (95% CI, 14.6%-15.3%), and mean cost per admission was $13 241 (95% CI, $12 957-$13 525). After ranking the 35 procedure groups by contribution to EGS mortality and morbidity burden, a final set of 7 operative EGS procedures were identified, which collectively accounted for 80.0% of procedures, 80.3% of deaths, 78.9% of complications, and 80.2% of inpatient costs nationwide. These 7 procedures included partial colectomy, small-bowel resection, cholecystectomy, operative management of peptic ulcer disease, lysis of peritoneal adhesions, appendectomy, and laparotomy. Only 7 procedures account for most admissions, deaths, complications, and inpatient costs attributable to the 512 079 EGS procedures performed in the United States each year. National quality benchmarks and cost reduction efforts should focus on these common, complicated, and costly EGS procedures.

  15. U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION, CALIBRATION, AND ROUTINE USE OF THE SPECTRACE 9000 FIELD PORTABLE X-RAY FLUORESCENCE ANALYZER (UA-L-10.1)

    EPA Science Inventory

    The purpose of this SOP is to describe the procedures for operating and calibrating the Spectrace 9000 field portable X-ray fluorescence analyzer. This procedure applies to the determination of metal concentrations in samples during the Arizona NHEXAS project and the Border stud...

  16. U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION AND MAINTENANCE OF THE ECOCHEM REAL-TIME AMBIENT AIR PAH MONITOR (UA-F-24.0)

    EPA Science Inventory

    The purpose of this SOP is to describe the general procedures to be followed for the operation and maintenance of the EcoChem real-time ambient air PAH monitor. This procedure was followed to ensure consistent data retrieval of PAH measurements during the Arizona NHEXAS project ...

  17. U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION, CALIBRATION, AND MAINTENANCE OF THE PERKIN-ELMER 5100 PC ATOMIC ABSORPTION SPECTROMETER (BCO-L-5.1)

    EPA Science Inventory

    The purpose of this SOP is to outline the start-up, calibration, operation, and maintenance procedures for the Perkin-Elmer 5100 PC Atomic Absorption Spectrophotometer (PE 5100). These procedures are used for the determination of the target trace metal, as in soil, house dust, f...

  18. Operational procedures for ground station operation: ATS-3 Hawaii-Ames satellite link experiment

    NASA Technical Reports Server (NTRS)

    Nishioka, K.; Gross, E. H.

    1979-01-01

    Hardware description and operational procedures for the ATS-3 Hawaii-Ames satellite computer link are presented in basic step-by-step instructions. Transmit and receive channels and frequencies are given. Details such as switch settings for activating the station to the sequence of turning switches on are provided. Methods and procedures for troubleshooting common problems encountered with communication stations are also provided.

  19. 40 CFR 60.4244 - What test methods and other procedures must I use if I am an owner or operator of a stationary SI...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false What test methods and other procedures... Internal Combustion Engines Testing Requirements for Owners and Operators § 60.4244 What test methods and...? Owners and operators of stationary SI ICE who conduct performance tests must follow the procedures in...

  20. 40 CFR 60.4244 - What test methods and other procedures must I use if I am an owner or operator of a stationary SI...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What test methods and other procedures... Internal Combustion Engines Testing Requirements for Owners and Operators § 60.4244 What test methods and...? Owners and operators of stationary SI ICE who conduct performance tests must follow the procedures in...

  1. 40 CFR 60.4244 - What test methods and other procedures must I use if I am an owner or operator of a stationary SI...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false What test methods and other procedures... Internal Combustion Engines Testing Requirements for Owners and Operators § 60.4244 What test methods and...? Owners and operators of stationary SI ICE who conduct performance tests must follow the procedures in...

  2. 40 CFR 60.4244 - What test methods and other procedures must I use if I am an owner or operator of a stationary SI...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false What test methods and other procedures... Internal Combustion Engines Testing Requirements for Owners and Operators § 60.4244 What test methods and...? Owners and operators of stationary SI ICE who conduct performance tests must follow the procedures in...

  3. 40 CFR 60.4244 - What test methods and other procedures must I use if I am an owner or operator of a stationary SI...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false What test methods and other procedures... Internal Combustion Engines Testing Requirements for Owners and Operators § 60.4244 What test methods and...? Owners and operators of stationary SI ICE who conduct performance tests must follow the procedures in...

  4. SATS HVO Concept Validation Experiment

    NASA Technical Reports Server (NTRS)

    Consiglio, Maria; Williams, Daniel; Murdoch, Jennifer; Adams, Catherine

    2005-01-01

    A human-in-the-loop simulation experiment was conducted at the NASA Langley Research Center s (LaRC) Air Traffic Operations Lab (ATOL) in an effort to comprehensively validate tools and procedures intended to enable the Small Aircraft Transportation System, Higher Volume Operations (SATS HVO) concept of operations. The SATS HVO procedures were developed to increase the rate of operations at non-towered, non-radar airports in near all-weather conditions. A key element of the design is the establishment of a volume of airspace around designated airports where pilots accept responsibility for self-separation. Flights operating at these airports, are given approach sequencing information computed by a ground based automated system. The SATS HVO validation experiment was conducted in the ATOL during the spring of 2004 in order to determine if a pilot can safely and proficiently fly an airplane while performing SATS HVO procedures. Comparative measures of flight path error, perceived workload and situation awareness were obtained for two types of scenarios. Baseline scenarios were representative of today s system utilizing procedure separation, where air traffic control grants one approach or departure clearance at a time. SATS HVO scenarios represented approaches and departure procedures as described in the SATS HVO concept of operations. Results from the experiment indicate that low time pilots were able to fly SATS HVO procedures and maintain self-separation as safely and proficiently as flying today's procedures.

  5. 47 CFR 36.391 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROCEDURES; STANDARD PROCEDURES FOR SEPARATING TELECOMMUNICATIONS PROPERTY COSTS, REVENUES, EXPENSES, TAXES AND RESERVES FOR TELECOMMUNICATIONS COMPANIES 1 Operating Expenses and Taxes Corporate Operations Expense § 36.391 General. Corporate Operations Expenses are included in the following account: General and...

  6. 47 CFR 1.83 - Applications for radio operator licenses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Applications for radio operator licenses. 1.83... Rules of Practice and Procedure Miscellaneous Proceedings § 1.83 Applications for radio operator licenses. (a) Application filing procedures for amateur radio operator licenses are set forth in part 97 of...

  7. 18 CFR 376.209 - Procedures during periods of emergency requiring activation of the Continuity of Operations Plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... periods of emergency requiring activation of the Continuity of Operations Plan. 376.209 Section 376.209... GENERAL RULES ORGANIZATION, MISSION, AND FUNCTIONS; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.209 Procedures during periods of emergency requiring activation...

  8. 14 CFR 93.71 - General operating procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of Niagara Falls, New York § 93.71 General operating procedures. (a) Flight restrictions are in effect below 3,500 feet MSL in the airspace above Niagara Falls, New York, west of a line from latitude..., aircraft operating on an ATC-approved IFR flight plan, aircraft operating the Scenic Falls Route pursuant...

  9. 14 CFR 93.71 - General operating procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... of Niagara Falls, New York § 93.71 General operating procedures. (a) Flight restrictions are in effect below 3,500 feet MSL in the airspace above Niagara Falls, New York, west of a line from latitude..., aircraft operating on an ATC-approved IFR flight plan, aircraft operating the Scenic Falls Route pursuant...

  10. 14 CFR 93.71 - General operating procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... of Niagara Falls, New York § 93.71 General operating procedures. (a) Flight restrictions are in effect below 3,500 feet MSL in the airspace above Niagara Falls, New York, west of a line from latitude..., aircraft operating on an ATC-approved IFR flight plan, aircraft operating the Scenic Falls Route pursuant...

  11. Improving the safety and quality of nursing care through standardized operating procedures in Bosnia and Herzegovina.

    PubMed

    Ausserhofer, Dietmar; Rakic, Severin; Novo, Ahmed; Dropic, Emira; Fisekovic, Eldin; Sredic, Ana; Van Malderen, Greet

    2016-06-01

    We explored how selected 'positive deviant' healthcare facilities in Bosnia and Herzegovina approach the continuous development, adaptation, implementation, monitoring and evaluation of nursing-related standard operating procedures. Standardized nursing care is internationally recognized as a critical element of safe, high-quality health care; yet very little research has examined one of its key instruments: nursing-related standard operating procedures. Despite variability in Bosnia and Herzegovina's healthcare and nursing care quality, we assumed that some healthcare facilities would have developed effective strategies to elevate nursing quality and safety through the use of standard operating procedures. Guided by the 'positive deviance' approach, we used a multiple-case study design to examine a criterion sample of four facilities (two primary healthcare centres and two hospitals), collecting data via focus groups and individual interviews. In each studied facility, certification/accreditation processes were crucial to the initiation of continuous development, adaptation, implementation, monitoring and evaluation of nursing-related SOPs. In one hospital and one primary healthcare centre, nurses working in advanced roles (i.e. quality coordinators) were responsible for developing and implementing nursing-related standard operating procedures. Across the four studied institutions, we identified a consistent approach to standard operating procedures-related processes. The certification/accreditation process is enabling necessary changes in institutions' organizational cultures, empowering nurses to take on advanced roles in improving the safety and quality of nursing care. Standardizing nursing procedures is key to improve the safety and quality of nursing care. Nursing and Health Policy are needed in Bosnia and Herzegovina to establish a functioning institutional framework, including regulatory bodies, educational systems for developing nurses' capacities or the inclusion of nursing-related standard operating procedures in certification/accreditation standards. © 2016 International Council of Nurses.

  12. Laparoscopic versus robotic-assisted Roux-en-Y gastric bypass: a retrospective, single-center study of early perioperative outcomes at a community hospital.

    PubMed

    Ahmad, Arif; Carleton, Jared D; Ahmad, Zoha F; Agarwala, Ashish

    2016-09-01

    The purpose of this study was to compare the operative and early perioperative outcomes of laparoscopic versus robotic-assisted Roux-en-Y gastric bypass procedures performed in a community hospital setting. The study was a chart review and analysis of the early perioperative outcomes of a total of 345 Roux-en-Y gastric bypass procedures performed by a single surgeon in a community hospital setting from January 2011 to October 2014. Of these, 173 procedures were performed laparoscopically and 172 were performed with robotic assistance utilizing the daVinci(®) surgical platform. Factors such as baseline patient characteristics, operative time, estimated blood loss (EBL), conversions to open procedure, complication rates, adverse events, length of stay (LOS), and return to the operating room for the two groups were retrospectively analyzed from a prospectively maintained database. Student's t test with unequal variances was used for statistical analysis, and a p value <0.05 was used for significance. There were no statistically significant differences in complication rates, EBL, or LOS between the two groups. There was a significant difference between the total operative times (135.30 ± 37.60 min for the laparoscopic procedure versus 154.84 ± 38.44 min for the robotic procedure, p < 0.05). There were no adverse intraoperative events, conversions to open procedures, leaks, strictures, returns to the operating room within 30 days, or mortalities in either group. Our study, which is the first of its kind to analyze the operative and early perioperative outcomes between laparoscopic and robotic-assisted Roux-en-Y gastric bypass procedures in the US community hospital setting, indicates that both are comparable in terms of safety, efficacy, and operative and early perioperative outcomes.

  13. Review and meta-analysis of prospective randomized controlled trials (RCTs) comparing laparo-endoscopic single site and multiport laparoscopy in gynecologic operative procedures.

    PubMed

    Pontis, Alessandro; Sedda, Federica; Mereu, Liliana; Podda, Mauro; Melis, Gian Benedetto; Pisanu, Adolfo; Angioni, Stefano

    2016-09-01

    To critically appraise published randomized controlled trials (RCTs) comparing laparo-endoscopic single site (LESS) and multi-port laparoscopic (MPL) in gynecologic operative surgery; the aim was to assess feasibility, safety, and potential benefits of LESS in comparison to MPL. A systematic review and meta-analysis of eleven RCTs. Women undergoing operative LESS and MPL gynecologic procedure (hysterectomy, cystectomy, salpingectomy, salpingo-oophorectomy, myomectomy). Outcomes evaluated were as follows: postoperative overall morbidity, postoperative pain evaluation at 6, 12, 24 and 48 h, cosmetic patient satisfaction, conversion rate, body mass index (BMI), operative time, blood loss, hemoglobin drop, postoperative hospital stay. Eleven RCTs comprising 956 women with gynecologic surgical disease randomized to either LESS (477) or MPL procedures (479) were analyzed systematically. The LESS approach is a surgical procedure with longer operative and better cosmetic results time than MPL but without statistical significance. Operative outcomes, postoperative recovery, postoperative morbidity and patient satisfaction are similar in LESS and MPL. LESS may be considered an alternative to MPL with comparable feasibility and safety in gynecologic operative procedures. However, it does not offer the expected advantages in terms of postoperative pain and cosmetic satisfaction.

  14. Evaluation of noise pollution level in the operating rooms of hospitals: A study in Iran.

    PubMed

    Giv, Masoumeh Dorri; Sani, Karim Ghazikhanlou; Alizadeh, Majid; Valinejadi, Ali; Majdabadi, Hesamedin Askari

    2017-06-01

    Noise pollution in the operating rooms is one of the remaining challenges. Both patients and physicians are exposed to different sound levels during the operative cases, many of which can last for hours. This study aims to evaluate the noise pollution in the operating rooms during different surgical procedures. In this cross-sectional study, sound level in the operating rooms of Hamadan University-affiliated hospitals (totally 10) in Iran during different surgical procedures was measured using B&K sound meter. The gathered data were compared with national and international standards. Statistical analysis was performed using descriptive statistics and one-way ANOVA, t -test, and Pearson's correlation test. Noise pollution level at majority of surgical procedures is higher than national and international documented standards. The highest level of noise pollution is related to orthopedic procedures, and the lowest one related to laparoscopic and heart surgery procedures. The highest and lowest registered sound level during the operation was 93 and 55 dB, respectively. Sound level generated by equipments (69 ± 4.1 dB), trolley movement (66 ± 2.3 dB), and personnel conversations (64 ± 3.9 dB) are the main sources of noise. The noise pollution of operating rooms are higher than available standards. The procedure needs to be corrected for achieving the proper conditions.

  15. 42 CFR 422.202 - Participation procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... procedures. (a) Notice and appeal rights. An MA organization that operates a coordinated care plan or network... of groups of physicians, through reasonable procedures that include the following: (1) Written notice... guidelines. (c) Subcontracted groups. An MA organization that operates an MA plan through subcontracted...

  16. Procedural Portfolio Planning in Plastic Surgery, Part 2: Collaboration Between Surgeons and Hospital Administrators to Develop a Funds Flow Model for Procedures Performed at an Academic Medical Center.

    PubMed

    Hultman, Charles Scott

    2016-06-01

    Although plastic surgeons make important contributions to the clinical, educational, and research missions of academic medical centers (AMCs), determining the financial value of a plastic surgery service can be difficult, due to complex cost accounting systems. We analyzed the financial impact of plastic surgery on an AMC, by examining the contribution margins and operating income of surgical procedures. We collaborated with hospital administrators to implement 3 types of strategic changes: (1) growth of areas with high contribution margin, (2) curtailment of high-risk procedures with negative contribution margin, (3) improved efficiency of mission-critical services with high resource consumption. Outcome measures included: facility charges, hospital collections, contribution margin, operating margin, and operating room times. We also studied the top 50 Current Procedural Terminology codes (total case number × charge/case), ranking procedures for profitability, as determined by operating margin. During the 2-year study period, we had no turnover in faculty; did not pursue any formal marketing; did not change our surgical fees, billing system, or payer mix; and maintained our commitment to indigent care. After rebalancing our case mix, through procedural portfolio planning, average hospital operating income/procedure increased from $-79 to $+816. Volume and diversity of cases increased, with no change in payer mix. Although charges/case decreased, both contribution margin and operating margin increased, due to improved throughput and decreased operating room times. The 5 most profitable procedures for the hospital were hernia repair, mandibular osteotomy, hand skin graft, free fibula flap, and head and neck flap, whereas the 5 least profitable were latissimus breast reconstruction, craniosynostosis repair, free-flap breast reconstruction, trunk skin graft, and cutaneous free flap. Total operating income for the hospital, from plastic surgery procedures, increased from $-115,103 to $+1,277,040, of which $350,000 (25%) was returned to the practice plan as enterprise funds to support program development. Through focused strategic initiatives, plastic surgeons and hospital administrators can work together to unlock the latent value of a plastic surgery service to an AMC. Specific financial benefits to the hospital include increased contribution margin and operating income, the latter of which can be reinvested in the plastic surgery service through a gain-sharing model.

  17. Improving Small Signal Stability through Operating Point Adjustment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Zhenyu; Zhou, Ning; Tuffner, Francis K.

    2010-09-30

    ModeMeter techniques for real-time small signal stability monitoring continue to mature, and more and more phasor measurements are available in power systems. It has come to the stage to bring modal information into real-time power system operation. This paper proposes to establish a procedure for Modal Analysis for Grid Operations (MANGO). Complementary to PSS’s and other traditional modulation-based control, MANGO aims to provide suggestions such as increasing generation or decreasing load for operators to mitigate low-frequency oscillations. Different from modulation-based control, the MANGO procedure proactively maintains adequate damping for all time, instead of reacting to disturbances when they occur. Effectmore » of operating points on small signal stability is presented in this paper. Implementation with existing operating procedures is discussed. Several approaches for modal sensitivity estimation are investigated to associate modal damping and operating parameters. The effectiveness of the MANGO procedure is confirmed through simulation studies of several test systems.« less

  18. 47 CFR 36.373 - Services-Account 6620.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROCEDURES; STANDARD PROCEDURES FOR SEPARATING TELECOMMUNICATIONS PROPERTY COSTS, REVENUES, EXPENSES, TAXES AND RESERVES FOR TELECOMMUNICATIONS COMPANIES 1 Operating Expenses and Taxes Customer Operations... among the operations for groups of exchanges. A group of exchanges may include all exchanges in the...

  19. Effective and efficient learning in the operating theater with intraoperative video-enhanced surgical procedure training.

    PubMed

    van Det, M J; Meijerink, W J H J; Hoff, C; Middel, B; Pierie, J P E N

    2013-08-01

    INtraoperative Video Enhanced Surgical procedure Training (INVEST) is a new training method designed to improve the transition from basic skills training in a skills lab to procedural training in the operating theater. Traditionally, the master-apprentice model (MAM) is used for procedural training in the operating theater, but this model lacks uniformity and efficiency at the beginning of the learning curve. This study was designed to investigate the effectiveness and efficiency of INVEST compared to MAM. Ten surgical residents with no laparoscopic experience were recruited for a laparoscopic cholecystectomy training curriculum either by the MAM or with INVEST. After a uniform course in basic laparoscopic skills, each trainee performed six cholecystectomies that were digitally recorded. For 14 steps of the procedure, an observer who was blinded for the type of training determined whether the step was performed entirely by the trainee (2 points), partially by the trainee (1 point), or by the supervisor (0 points). Time measurements revealed the total procedure time and the amount of effective procedure time during which the trainee acted as the operating surgeon. Results were compared between both groups. Trainees in the INVEST group were awarded statistically significant more points (115.8 vs. 70.2; p < 0.001) and performed more steps without the interference of the supervisor (46.6 vs. 18.8; p < 0.001). Total procedure time was not lengthened by INVEST, and the part performed by trainees was significantly larger (69.9 vs. 54.1 %; p = 0.004). INVEST enhances effectiveness and training efficiency for procedural training inside the operating theater without compromising operating theater time efficiency.

  20. 47 CFR 36.376 - All other.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROCEDURES; STANDARD PROCEDURES FOR SEPARATING TELECOMMUNICATIONS PROPERTY COSTS, REVENUES, EXPENSES, TAXES AND RESERVES FOR TELECOMMUNICATIONS COMPANIES 1 Operating Expenses and Taxes Customer Operations...

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