Sample records for optical clearing solution

  1. Optical clearing: impact of optical and dielectric properties of clearing solutions on pulmonary tissue mechanics.

    PubMed

    Schwenninger, David; Priebe, Hans-Joachim; Schneider, Matthias; Runck, Hanna; Guttmann, Josef

    2017-07-01

    Optical clearing allows tissue visualization under preservation of organ integrity. Optical clearing of organs with a physiological change in three-dimensional geometry (such as the lung) would additionally allow visualization of macroscopic and microscopic tissue geometry. A prerequisite, however, is the preservation of the native tissue mechanics of the optically cleared lung tissue. We investigated the impact of optical and dielectric properties of clearing solutions on biomechanics and clearing potency in porcine tissue strips of healthy lungs. After fixation, bleaching, and rehydration, four methods of optical clearing were investigated using eight different protocols. The mechanical and optical properties of the cleared lung tissue strips were investigated by uniaxial tensile testing and by analyzing optical transparency and translucency for red, green, and blue light before, during, and after the biochemical optical clearing process. Fresh tissue strips were used as controls. Best balance between efficient clearing and preserved mechanics was found for clearing with a 1:1 mixture of dimethyl sulfoxide (DMSO) and aniline. Our findings show that 1 ) the degree of tissue transparency and translucency correlated with the refractive index of the clearing solution index ( r = 0.976, P = 0.0004; and r = 0.91, P = 0.0046, respectively), 2 ) tissue mechanics were affected by dehydration and the type of clearing solution, and 3 ) tissue biomechanics and geometry correlated with the dielectric constant of the clearing solution ( r = -0.98, P < 0.00001; and r = 0.69, P = 0.013, respectively). We show that the lower the dielectric constant of the clearing solutions, the larger the effect on tissue stiffness. This suggests that the dielectric constant is an important measure in determining the effect of a clearing solution on lung tissue biomechanics. Optimal tissue transparency requires complete tissue dehydration and a refractive index of 1.55 of the clearing solution. NEW & NOTEWORTHY Investigating optical clearing in porcine lung tissue strips, we found that refractive index and dielectric constant of the clearing solution affected tissue clearing and biomechanics. By documenting the impact of the composition of the clearing solution on clearing potency and preservation of tissue mechanics, our results help to compose optimal clearing solutions. In addition, the results allow conclusions on the molecular interaction of solvents with collagen fibers in tissue, thereby consolidating existing theories about the functionality of collagen. Copyright © 2017 the American Physiological Society.

  2. Laser speckle contrast imaging of cerebral blood flow of newborn mice at optical clearing

    NASA Astrophysics Data System (ADS)

    Timoshina, Polina A.; Zinchenko, Ekaterina M.; Tuchina, Daria K.; Sagatova, Madina M.; Semyachkina-Glushkovskaya, Oxana V.; Tuchin, Valery V.

    2017-03-01

    In this work, we consider the use of optical clearing agents to improve imaging quality of the cerebral blood flow of newborn mice. Aqueous 60%-glycerol solution, aqueous 70%-OmnipaqueTM(300) solution and OmnipaqueTM (300) solution in water/DMSO(25%/5%) were selected as the optical clearing agents. Laser speckle contrast imaging (LSCI) was used for imaging of cerebral blood flow in newborn mice brain during topical optical clearing of tissuesin the area of the fontanelle. These results demonstrate the effectiveness of glycerol and Omnipaque solutions as optical clearing agents for investigation of cerebral blood flow in newborn mice without scalp removing and skull thinning.

  3. In vivo comparison of the optical clearing efficacy of optical clearing agents in human skin by quantifying permeability using optical coherence tomography.

    PubMed

    Guo, Xiao; Guo, Zhouyi; Wei, Huajiang; Yang, Hongqin; He, Yonghong; Xie, Shusen; Wu, Guoyong; Deng, Xiaoyuan; Zhao, Qingliang; Li, Lanquan

    2011-01-01

    The objective of this work is to quantify and compare the optical clearing efficacy of glucose, propylene glycol, glycerol solutions through the human skin tissue in vivo by calculating permeability coefficient of three solutions. Currently, the permeability coefficient of agent in tissues was extracted from optical coherence tomography (OCT) amplitude data mainly through the OCT signal slope and the OCT amplitude methods. In this study, we report the OCT attenuation coefficient method which is a relatively novel and rarely reported methodology to measure the permeability coefficient during the optical skin clearing procedure. The permeability coefficients for 40% propylene glycol, glucose and glycerol were (2.74 ± 0.05) × 10(-6) cm s(-1), (1.78 ± 0.04) × 10(-6) cm s(-1) and (1.67 ± 0.04) × 10(-6) cm s(-1), respectively. It could be clearly seen that the permeability coefficient of the 40% propylene glycol solution is higher than that of 40% glucose solution, and the permeability coefficient of the 40% glucose solution is higher than that of the 40% glycerol solution. These indicate 40% propylene glycol solution is more effective than others in the human skin in vivo. We then compare and prove consistency of optical clearing efficacy figured out by three different methods. © 2011 The Authors. Photochemistry and Photobiology © 2011 The American Society of Photobiology.

  4. Recent progress in tissue optical clearing

    PubMed Central

    Zhu, Dan; Larin, Kirill V; Luo, Qingming; Tuchin, Valery V

    2013-01-01

    Tissue optical clearing technique provides a prospective solution for the application of advanced optical methods in life sciences. This paper gives a review of recent developments in tissue optical clearing techniques. The physical, molecular and physiological mechanisms of tissue optical clearing are overviewed and discussed. Various methods for enhancing penetration of optical-clearing agents into tissue, such as physical methods, chemical-penetration enhancers and combination of physical and chemical methods are introduced. Combining the tissue optical clearing technique with advanced microscopy image or labeling technique, applications for 3D microstructure of whole tissues such as brain and central nervous system with unprecedented resolution are demonstrated. Moreover, the difference in diffusion and/or clearing ability of selected agents in healthy versus pathological tissues can provide a highly sensitive indicator of the tissue health/pathology condition. Finally, recent advances in optical clearing of soft or hard tissue for in vivo imaging and phototherapy are introduced. PMID:24348874

  5. Optical clearing of articular cartilage: a comparison of clearing agents

    NASA Astrophysics Data System (ADS)

    Bykov, Alexander; Hautala, Tapio; Kinnunen, Matti; Popov, Alexey; Karhula, Sakari; Saarakkala, Simo; Nieminen, Miika T.; Tuchin, Valery

    2015-07-01

    Optical clearing technique was applied to the problem of OCT imaging of articular cartilage and subchondral bone. We show that optical clearing significantly enhances visualization of articular cartilage and cartilage-bone interface. The effect of different clearing agents was analyzed. For the clearing, iohexol solution and propylene glycol (PG) were used. Clearing was performed in vitro at room temperature by immersion method. Cylindrical osteochondral samples (d=4.8mm) were drilled from bovine lateral femur and stored in phosphate-buffered saline at -20°C until clearing. Monitoring of clearing process was performed using high-speed spectral-domain OCT system providing axial resolution of 5.8μm at 930nm. Total duration of experiment was 90-100min to ensure saturation of clearing. We have shown that iohexol solution and PG are capable to optically clear articular cartilage enabling reliable characterization of cartilagebone interface with OCT. Being a low osmolarity agent, iohexol provides minimal changes to the thickness of cartilage sample. Clearing saturation time for the cartilage sample with the thickness of 0.9 mm measured with OCT is of 50 min. However, less than 15 min is enough to reliably detect the rear cartilage boundary. Alternatively, PG significantly (60%) reduces the cartilage thickness enabling better visualization of subchondral bone. It was observed that PG has higher clearing rate. The clearing saturation time is of 30 min, however less than 5 min is enough to detect cartilage-bone interface. We conclude that iohexol solution is superior for OCT imaging of cartilage and cartilage-bone interface, while PG suits better for subhondral bone visualization.

  6. Quantitative assessment of hyaline cartilage elasticity during optical clearing using optical coherence elastography

    NASA Astrophysics Data System (ADS)

    Liu, Chih-Hao; Singh, Manmohan; Li, Jiasong; Han, Zhaolong; Wu, Chen; Wang, Shang; Idugboe, Rita; Raghunathan, Raksha; Zakharov, Valery P.; Sobol, Emil N.; Tuchin, Valery V.; Twa, Michael; Larin, Kirill V.

    2015-03-01

    We report the first study on using optical coherence elastography (OCE) to quantitatively monitor the elasticity change of the hyaline cartilage during the optical clearing administrated by glucose solution. The measurement of the elasticity is verified using uniaxial compression test, demonstrating the feasibility of using OCE to quantify the Young's modulus of the cartilage tissue. As the results, we found that the stiffness of the hyaline cartilage increases during the optical clearing of the tissue. This study might be potentially useful for the early detection of osteoarthritis disease.

  7. Study on application of optical clearing technique in skin diseases

    NASA Astrophysics Data System (ADS)

    Shan, Hao; Liang, Yanmei; Wang, Jingyi; Li, Yan

    2012-11-01

    So far, the study of the optical clearing is almost always about healthy tissue. However, the ultimate goal is to detect diseases for clinical application. Optical clearing on diseased skins is explored. The effect is evaluated by applying a combined liquid paraffin and glycerol mixed solution on several kinds of diseased skins in vitro. Scanning experiments from optical coherence tomography show that it has different effects among fibroma, pigmented nevus, and seborrheic keratosis. Based on the results, we conclude that different skin diseases have different compositions and structures, and their optical parameters and biological characteristics should be different, which implies that the optical clearing technique may have selectivity and may not be suitable for all kinds of skin diseases.

  8. Assessment of laser-induced acceleration effects in optical clearing of in vivo human skin by optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Zhan, Zhigang; Wei, Huajiang; Jin, Ying

    2015-02-01

    Laser irradiation is considered to be a promising innovative technology which has been developed in an attempt to increase transdermal drug delivery. In this study, a near-infrared CW diode laser (785 nm) was applied to increase permeability of glycerol solutions in human skin in vivo and improve the optical clearing efficacy. Results show that for both 15%v/v and 30%v/v glycerol, the permeability coefficient increased significantly if the detected area of the skin tissue was treated with laser irradiation before optical clearing agents (OCAs) were applied. This study based on optical coherence tomography imaging technique and optical clearing effect finds laser irradiation a new approach for enhancing the penetration of OCAs and accelerating the rate of transdermal drug delivery.

  9. Optically pumped lasing and electroluminescence of formamidinium perovskite semiconductors prepared by the cast-capping method

    NASA Astrophysics Data System (ADS)

    Sasaki, Fumio; Nguyen, Van-Cao; Yanagi, Hisao

    2018-03-01

    Optically pumped lasing and electroluminescence (EL) have been observed in solution-processed perovskite semiconducting materials of formamidinium lead bromide, CH(NH2)2PbBr3. Microcavities with flat surfaces and sharp edges have been easily obtained by the simple solution process called the “cast-capping method”. The crystals show clear multimode lasing of Fabry-Pérot cavities. The mode intervals are well explained by the optical constants with large dispersions of the materials. We have also fabricated EL devices and obtained clear EL in a single layer of the materials, but the EL intensity has been quenched rapidly.

  10. Optical clearing of skin using flash lamp-induced enhancement of epidermal permeability.

    PubMed

    Tuchin, V V; Altshuler, G B; Gavrilova, A A; Pravdin, A B; Tabatadze, D; Childs, J; Yaroslavsky, I V

    2006-10-01

    Strong light scattering in skin prevents precise targeting of optical energy in therapeutic and diagnostic applications. Optical immersion based on matching refractive index of scattering centers with that of surrounding matter through introduction of an exogenous index-matching agent can alleviate the problem. However, slow diffusion of the index-matching agent through skin barrier makes practical implementation of this approach difficult. We propose a method of accelerating penetration of the index-matching compounds by enhancing skin permeability through creating a lattice of micro-zones (islets) of limited thermal damage in the stratum corneum (SC). A flash lamp (intense pulsed light) system and an island mask with a pattern of absorbing centers (center size approximately 75-120 microm, lattice pitch approximately 450-500 microm) were used to create the lattice of islets of damage (LID). Index-matching agents, such as glucose solution, propylene glycol solution, and glycerol solution, were applied. Experimental results of optical clearing ex vivo rat and pig skin, and ex vivo and in vivo human skin are presented. Optical transmission spectra of the skin samples with LID were measured during some 2 hours after application of index-matching chemical agents. In order to assess and compare the clearing rate under different treatment and clearing agents we calculated the quantity that we call "relative transmittance": T(rel) = I(t)(lambda)/I(0)(lambda), were I(t)(lambda) is the intensity measured at elapsed time t. The dynamics of relative transmittance of skin samples at 470 and 650 nm shows that the implementation of limited thermal damage technique leads to a 3-10-fold increase of optical clearing (rise of transmittance) rate compared to the results obtained when the samples were treated with high-intensity light pulses but without the use of island damage mask (IDM). It was observed from the plotted spectra of relative transmittance that the maximum increase of transmitted light intensity has been obtained with glucose solution as a clearing agent. Noteworthy is the difference in the trend of spectral curves: relative transmittance spectrum for glycerol reveals, on the whole, a greater slope which may be indicative of higher extent of index matching between the scattering centers and base material for this index-matching agent. Under the transillumination of the skin sample by the wide flat beam the more effective clearing (the increase of transmitted intensity) is attained within the hemoglobin absorption bands; with the narrow quasi-collimated beam the higher relative transmittance was observed over the intervals of minimum absorption. The use of specially designed island mask combined with non-laser intensive pulse irradiation produces a lattice of islands of limited thermal damage in SC that substantially enhances the penetration rate of topically applied index-matching agents. The suggested technique gave comparable magnitudes of clearing dynamics enhancement for glucose solution, glycerol solution, and propylene glycol solution applied to mammalian skin.

  11. Recent progress in tissue optical clearing for spectroscopic application

    NASA Astrophysics Data System (ADS)

    Sdobnov, A. Yu.; Darvin, M. E.; Genina, E. A.; Bashkatov, A. N.; Lademann, J.; Tuchin, V. V.

    2018-05-01

    This paper aims to review recent progress in optical clearing of the skin and over naturally turbid biological tissues and blood using this technique in vivo and in vitro with multiphoton microscopy, confocal Raman microscopy, confocal microscopy, NIR spectroscopy, optical coherence tomography, and laser speckle contrast imaging. Basic principles of the technique, its safety, advantages and limitations are discussed. The application of optical clearing agent on a tissue allows for controlling the optical properties of tissue. Optical clearing-induced reduction of tissue scattering significantly facilitates the observation of deep-located tissue regions, at the same time improving the resolution and image contrast for a variety of optical imaging methods suitable for clinical applications, such as diagnostics and laser treatment of skin diseases, mucosal tumor imaging, laser disruption of pathological abnormalities, etc. Structural images of different skin layers obtained ex vivo for porcine ear skin samples at application of Omnipaque™ and glycerol solutions during 60 min. Red color corresponds to TPEAF signal channel. Green color corresponds to SHG signal channel.

  12. Molecular effective coverage surface area of optical clearing agents for predicting optical clearing potential

    NASA Astrophysics Data System (ADS)

    Feng, Wei; Ma, Ning; Zhu, Dan

    2015-03-01

    The improvement of methods for optical clearing agent prediction exerts an important impact on tissue optical clearing technique. The molecular dynamic simulation is one of the most convincing and simplest approaches to predict the optical clearing potential of agents by analyzing the hydrogen bonds, hydrogen bridges and hydrogen bridges type forming between agents and collagen. However, the above analysis methods still suffer from some problem such as analysis of cyclic molecule by reason of molecular conformation. In this study, a molecular effective coverage surface area based on the molecular dynamic simulation was proposed to predict the potential of optical clearing agents. Several typical cyclic molecules, fructose, glucose and chain molecules, sorbitol, xylitol were analyzed by calculating their molecular effective coverage surface area, hydrogen bonds, hydrogen bridges and hydrogen bridges type, respectively. In order to verify this analysis methods, in vitro skin samples optical clearing efficacy were measured after 25 min immersing in the solutions, fructose, glucose, sorbitol and xylitol at concentration of 3.5 M using 1951 USAF resolution test target. The experimental results show accordance with prediction of molecular effective coverage surface area. Further to compare molecular effective coverage surface area with other parameters, it can show that molecular effective coverage surface area has a better performance in predicting OCP of agents.

  13. Enhanced in vivo visualization of the microcirculation by topical application of fructose solution confirmed with correlation mapping optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Enfield, Joey; McGrath, James; Daly, Susan M.; Leahy, Martin

    2016-08-01

    Changes within the microcirculation can provide an early indication of the onset of a plethora of ailments. Various techniques have thus been developed that enable the study of microcirculatory irregularities. Correlation mapping optical coherence tomography (cmOCT) is a recently proposed technique, which enables mapping of vasculature networks at the capillary level in a noninvasive and noncontact manner. This technique is an extension of conventional optical coherence tomography (OCT) and is therefore likewise limited in the penetration depth of ballistic photons in biological media. Optical clearing has previously been demonstrated to enhance the penetration depth and the imaging capabilities of OCT. In order to enhance the achievable maximum imaging depth, we propose the use of optical clearing in conjunction with the cmOCT technique. We demonstrate in vivo a 13% increase in OCT penetration depth by topical application of a high-concentration fructose solution, thereby enabling the visualization of vessel features at deeper depths within the tissue.

  14. Molecular modeling of the process of reversible dissolution of the collagen protein under the action of tissue-clearing agents

    NASA Astrophysics Data System (ADS)

    Dvoretsky, K. N.; Berezin, K. V.; Chernavina, M. L.; Likhter, A. M.; Shagautdinova, I. T.; Antonova, E. M.; Rybakov, A. V.; Grechukhina, O. N.; Tuchin, V. V.

    2018-04-01

    The interaction of glycerol immersion agent with collagen mimetic peptide ((GPH)9)3 and a fragment of the microfibril 5((GPH)12)3 was studied by the classical molecular dynamics method using the GROMACS software. The change in geometric parameters of collagen α-chains at various concentrations of an aqueous solution of glycerol is analyzed. It is shown that these changes nonlinearly depend on the concentration and are limited to a certain level, which correlates with the experimental data on optical clearing efficiency of human skin. A hypothesis on the cause of the decreased efficiency of optical skin clearing at high immersion agent concentrations is put forward. The molecular mechanism of immersion optical clearing of biological tissues is discussed.

  15. Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods

    PubMed Central

    Smolyanskaya, O. A.; Schelkanova, I. J.; Kulya, M. S.; Odlyanitskiy, E. L.; Goryachev, I. S.; Tcypkin, A. N.; Grachev, Ya. V.; Toropova, Ya. G.; Tuchin, V. V.

    2018-01-01

    The optical clearing method has been widely used for different spectral ranges where it provides tissue transparency. In this work, we observed the enhanced penetration of the terahertz waves inside biological samples (skin, kidney, and cornea) treated with glycerol solutions inducing changes of optical and dielectric properties. It was supported by the observed trend of free-to-bound water ratio measured by the nuclear magnetic resonance (NMR) method. The terahertz clearing efficiency was found to be less for diabetic samples than for normal ones. Results of the numerical simulation proved that pulse deformation is due to bigger penetration depth caused by the reduction of absorption and refraction at optical clearing. PMID:29541513

  16. Decalcification using ethylenediaminetetraacetic acid for clear microstructure imaging of cochlea through optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Lee, Jaeyul; Kim, Kanghae; Wijesinghe, Ruchire Eranga; Jeon, Doekmin; Lee, Sang Heun; Jeon, Mansik; Jang, Jeong Hun

    2016-08-01

    The aim of this study was to analyze the effectiveness of decalcification using ethylenediaminetetraacetic acid (EDTA) as an optical clearing method to enhance the depth visibility of internal soft tissues of cochlea. Ex vivo mouse and guinea pig cochlea samples were soaked in EDTA solutions for decalcification, and swept source optical coherence tomography (OCT) was used as imaging modality to monitor the decalcified samples consecutively. The monitored noninvasive cross-sectional images showed that the mouse and guinea pig cochlea samples had to be decalcified for subsequent 7 and 14 days, respectively, to obtain the optimal optical clearing results. Using this method, difficulties in imaging of internal cochlea microstructures of mice could be evaded. The obtained results verified that the depth visibility of the decalcified ex vivo samples was enhanced.

  17. Contrast enhancing solution for use in confocal microscopy

    DOEpatents

    Tannous, Zeina; Torres, Abel; Gonzalez, Salvador

    2006-10-31

    A method of optically detecting a tumor during surgery. The method includes imaging at least one test point defined on the tumor using a first optical imaging system to provide a first tumor image. The method further includes excising a first predetermined layer of the tumor for forming an in-vivo defect area. A predetermined contrast enhancing solution is disposed on the in-vivo defect area, which is adapted to interact with at least one cell anomaly, such as basal cell carcinoma, located on the in-vivo defect area for optically enhancing the cell anomaly. Thereafter the defect area can be optically imaged to provide a clear and bright representation of the cell anomaly to aid a surgeon while surgically removing the cell anomaly.

  18. Thermoinduced laser-assisted deposition of molybdenum from aqueous solutions

    NASA Astrophysics Data System (ADS)

    Kochemirovsky, Vladimir V.; Logunov, Lev S.; Zhigley, Elvira S.; Baranauskaite, Valeriia

    2015-05-01

    Local molybdenum deposit obtainment is promising for micro thermocouples creation on dielectric surfaces. This paper is dedicated to development of method of laser-induced molybdenum deposition from water-based solution of inorganic salt on Sitall st-50 and glass dielectric substrates, as well as research of solution composition, pH and substrate optical properties influence on result of laser-induced molybdenum deposition from solution. It was shown that depending on dielectric substrate type, as a result of laser-induced deposition metallic molybdenum or molybdenum dioxide deposit forms: molybdenum dioxide deposits in case of optically clear substrate and metallic molybdenum deposits in case of opaque glass-ceramics. While modelling interim case via using clouded glass, mixture of molybdenum and its oxide was successfully obtained.

  19. Confocal Raman microscopy supported by optical clearing treatment of the skin—influence on collagen hydration

    NASA Astrophysics Data System (ADS)

    Sdobnov, Anton Yu; Tuchin, Valery V.; Lademann, Juergen; E Darvin, Maxim

    2017-07-01

    Confocal Raman microscopy (CRM) is employed to study the skin physiology, drug permeation and skin disease monitoring. In order to increase the depth of investigations, the effect of optical clearing was observed on porcine ear skin ex vivo. The optical clearing agents (OCAs) glycerol and iohexol (Omnipaque™) were applied to the porcine ear skin and investigated by CRM after 30 and 60 min of treatment. The extent of optical clearing by utilizing concentrations of 70% glycerol and 100% Omnipaque™ was evaluated. The intensity of the skin-related Raman peaks significantly increased starting from the depth 160 µm for Omnipaque™ and 40 µm for glycerol (p  ⩽  0.05) after 60 min of treatment. The OCAs’ influence on the collagen hydration in the deep-located dermis was investigated. Both OCAs induce skin dehydration, but the effect of glycerol treatment (30 min and 60 min) is stronger. The obtained results demonstrate that with increasing the treatment time, both glycerol and Omnipaque™ solutions improve the optical clearing of porcine skin making the deep-located dermal regions able for investigations. At the used concentrations and time intervals, glycerol is more effective than Omnipaque™. However, Omnipaque™ is more promising than glycerol for future in vivo applications as it is an already approved pharmaceutic substance without any known impact on the skin structure.

  20. Light propagation in tissues with controlled optical properties

    NASA Astrophysics Data System (ADS)

    Tuchin, Valery V.; Maksimova, Irina L.; Zimnyakov, Dmitry A.; Kon, Irina L.; Mavlyutov, Albert H.; Mishin, Alexey A.

    1997-10-01

    Theoretical and computer modeling approaches, such as Mie theory, radiative transfer theory, diffusion wave correlation spectroscopy, and Monte Carlo simulation were used to analyze tissue optics during a process of optical clearing due to refractive index matching. Continuous wave transmittance and forward scattering measurement as well as intensity correlation experiments were used to monitor tissue structural and optical properties. As a control, tissue samples of the human sclera were taken. Osmotically active solutions, such as Trazograph, glucose, and polyethylene glycol, were used as chemicals. A characteristic time response of human scleral optical clearing the range 3 to 10 min was determined. The diffusion coefficients describing the permeability of the scleral samples to Trazograph were experimentally estimated; the average value was DT approximately equals (0.9 +/- 0.5) X 10-5 cm2/s. The results are general and can be used to describe many other fibrous tissues.

  1. On-chip clearing of arrays of 3-D cell cultures and micro-tissues.

    PubMed

    Grist, S M; Nasseri, S S; Poon, T; Roskelley, C; Cheung, K C

    2016-07-01

    Three-dimensional (3-D) cell cultures are beneficial models for mimicking the complexities of in vivo tissues, especially in tumour studies where transport limitations can complicate response to cancer drugs. 3-D optical microscopy techniques are less involved than traditional embedding and sectioning, but are impeded by optical scattering properties of the tissues. Confocal and even two-photon microscopy limit sample imaging to approximately 100-200 μm depth, which is insufficient to image hypoxic spheroid cores. Optical clearing methods have permitted high-depth imaging of tissues without physical sectioning, but they are difficult to implement for smaller 3-D cultures due to sample loss in solution exchange. In this work, we demonstrate a microfluidic platform for high-throughput on-chip optical clearing of breast cancer spheroids using the SeeDB, Clear(T2), and ScaleSQ clearing methods. Although all three methods are able to effectively clear the spheroids, we find that SeeDB and ScaleSQ more effectively clear the sample than Clear(T2); however, SeeDB induces green autofluorescence while ScaleS causes sample expansion. Our unique on-chip implementation permits clearing arrays of 3-D cultures using perfusion while monitoring the 3-D cultures throughout the process, enabling visualization of the clearing endpoint as well as monitoring of transient changes that could induce image artefacts. Our microfluidic device is compatible with on-chip 3-D cell culture, permitting the use of on-chip clearing at the endpoint after monitoring the same spheroids during their culture. This on-chip method has the potential to improve readout from 3-D cultures, facilitating their use in cell-based assays for high-content drug screening and other applications.

  2. In vitro study of the effects of ultrasound-mediated glycerol on optical attenuation of human normal and cancerous esophageal tissues with optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Zhang, Y. Q.; Wei, H. J.; Yang, H. Q.; Guo, Z. Y.; Xie, S. S.; Gu, H. M.; Guo, X.; Zhu, Z. G.

    2013-06-01

    Previous studies from our group have demonstrated that glucose solution can induce optical clearing enhancement of esophageal tissues with optical coherence tomography (OCT). The aims of this study were to evaluate the optical clearing effects of ultrasound-mediated optical clearing agents (OCAs) and to find more effective methods to distinguish human normal esophageal tissues (NE) and cancerous esophageal tissues (CE). Here we used the OCT technique to investigate the optical attenuation of NE and CE in vitro after treatment with 30% glycerol alone and glycerol combined with ultrasound, respectively. Experimental results showed that the averaged attenuation coefficient of CE was significantly larger than that of NE. The maximal decreases of averaged attenuation coefficients of NE and CE were approximately 48.7% and 36.2% after treatment with 30% glycerol alone, and they were significantly lower than those treated with 30% glycerol and ultrasound (57.5% in NE and 44.8% in CE). Moreover, after treatment with 30% glycerol alone, the averaged attenuation coefficients of NE and CE reached their minima in about 80 min and 65 min, respectively. The times were much shorter in NE and CE after treatment with glycerol with ultrasound, being about 62 min and 50 min, respectively. The results suggest that there is a significant difference in the optical properties of NE and CE, and that OCT with an ultrasound-OCAs combination has the ability to distinguish CE from NE.

  3. Secretory glands and microvascular systems imaged in aqueous solution by atmospheric scanning electron microscopy (ASEM).

    PubMed

    Yamazawa, Toshiko; Nakamura, Naotoshi; Sato, Mari; Sato, Chikara

    2016-12-01

    Exocrine glands, e.g., salivary and pancreatic glands, play an important role in digestive enzyme secretion, while endocrine glands, e.g., pancreatic islets, secrete hormones that regulate blood glucose levels. The dysfunction of these secretory organs immediately leads to various diseases, such as diabetes or Sjögren's syndrome, by poorly understood mechanisms. Gland-related diseases have been studied by optical microscopy (OM), and at higher resolution by transmission electron microscopy (TEM) of Epon embedded samples, which necessitates hydrophobic sample pretreatment. Here, we report the direct observation of tissue in aqueous solution by atmospheric scanning electron microscopy (ASEM). Salivary glands, lacrimal glands, and pancreas were fixed, sectioned into slabs, stained with phosphotungstic acid (PTA), and inspected in radical scavenger d-glucose solution from below by an inverted scanning electron microscopy (SEM), guided by optical microscopy from above to target the tissue substructures. A 2- to 3-µm specimen thickness was visualized by the SEM. In secretory cells, cytoplasmic vesicles and other organelles were clearly imaged at high resolution, and the former could be classified according to the degree of PTA staining. In islets of Langerhans, the microvascular system used as an outlet by the secretory cells was also clearly observed. Microvascular system is also critically involved in the onset of diabetic complications and was clearly visible in subcutaneous tissue imaged by ASEM. The results suggest the use of in-solution ASEM for histology and to study vesicle secretion systems. Further, the high-throughput of ASEM makes it a potential tool for the diagnosis of exocrine and endocrine-related diseases. © 2016 Wiley Periodicals, Inc.

  4. A sealed optical cell for the study of lithium-electrode|electrolyte interfaces

    NASA Astrophysics Data System (ADS)

    Howlett, P. C.; MacFarlane, D. R.; Hollenkamp, A. F.

    A sealed, symmetrical, lithium optical cell, which enables optical images of lithium surface deposits and in situ Raman spectra to be obtained simply and conveniently during charge-discharge cycling of lithium metal electrodes, has been designed and tested. A conventional aprotic liquid, 1 M lithium hexafluorophosphate in propylene carbonate, and an experimental ionic liquid, 20 mol% lithium bis(trifluoromethanesulfonyl)amide in 1-ethyl 3-methyl imidazolium bis(trifluoromethanesulfonyl)amide, are investigated as electrolyte solutions. Images obtained from the cell with the former electrolyte solution demonstrate the problems associated with cycling lithium metal electrodes. Images obtained with the latter electrolyte solution provide clear evidence that continued investigation of ionic liquids for use with lithium metal electrodes is warranted. Operation of the cell with the conventional electrolyte yields Raman spectra of good quality. The spectra display vibrational modes which arise from the electrolyte, as well as several additional modes which are associated with the deposits formed during cycling.

  5. Solution of reduced graphene oxide synthesized from coconut shells and its optical properties

    NASA Astrophysics Data System (ADS)

    Mas'udah, Kusuma Wardhani; Nugraha, I. Made Ananta; Abidin, Saiful; Mufid, Ali; Astuti, Fahmi; Darminto

    2016-04-01

    Reduced graphene oxide (r-GO)powder has been prepared from coconut shells by carbonization process at 400°C for 3, 4 and 5 hours.Theresulted sample mass was reduced to be 60% relativelycompared to the starting material. The longer heating duration has also led to the rGO with reduced crystalinity according to the X-ray diffractometry data and TEM. The rGO solution was prepared by adding powders of 5, 10 and 15 grams into 50 ml destiled water and then centrifused at 6000 rpm for 30 minutes.The resulted solutions were seen to be varied form clear transparant, light and dark yellow to black. Measurement using particle size analyser shows that the individual rGO particles tends to be agglomerating each others to form bigger size clustering, manifested by the observed bigger size particles for the increasing amount of soluted rGO powders in water.The varying UV-visible spectra of these rGO solutions together with their optical bandgaps will also be discussed in this study.

  6. Silver nanoparticles as optical clearing agent enhancers to improve caries diagnostic by optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Carneiro, Vanda S. M.; Mota, Cláudia C. B. O.; Souza, Alex F.; da Silva, Evair J.; da Silva, Andrea F.; Gerbi, Marleny E. M. M.; Gomes, Anderson S. L.

    2018-02-01

    The use of silver nanoparticles as optical clearing agent (OCA) enhancers to improve caries diagnostic by optical coherence tomography (OCT) is demonstrated here. Five molars with no evident cavitation were selected. The OCAs were based on aqueous solution of silver nanoparticles (AgNP, 1.18x 1014 particles/mL, ø ≈ 10nm) and its dilution at 10% in glycerol. Teeth were placed on a platform with a micrometric screw, and after applying the OCAs, they were scanned with a Callisto SD-OCT system operating ate 930nm central wavelength. The occlusal surfaces were scanned by OCT, capturing crosssectional images with 8 mm transversal scanning, generating numerical matrices (2000x512). The OCT images had their transverse dimension preserved. AgNP-OCAs promoted image stretching due to the modification in the light optical path caused by AgNP-OCAs refractive indices close to that of the enamel. AgNP-OCAs evidenced the enamel birefringence and highlighted initial demineralization areas, that presented defined margins with higher contrast between sound and demineralized regions, with higher OCT signal intensity in those areas.

  7. Optical clearing of skin enhanced with hyaluronic acid for increased contrast of optoacoustic imaging

    NASA Astrophysics Data System (ADS)

    Liopo, Anton; Su, Richard; Tsyboulski, Dmitri A.; Oraevsky, Alexander A.

    2016-08-01

    Enhanced delivery of optical clearing agents (OCA) through skin may improve sensitivity of optical and optoacoustic (OA) methods of imaging, sensing, and monitoring. This report describes a two-step method for enhancement of light penetration through skin. Here, we demonstrate that topical application of hyaluronic acid (HA) improves skin penetration of hydrophilic and lipophilic OCA and thus enhances their performance. We examined the OC effect of 100% polyethylene and polypropylene glycols (PPGs) and their mixture after pretreatment by HA, and demonstrated significant increase in efficiency of light penetration through skin. Increased light transmission resulted in a significant increase of OA image contrast in vitro. Topical pretreatment of skin for about 30 min with 0.5% HA in aqueous solution offers effective delivery of low molecular weight OCA such as a mixture of PPG-425 and polyethylene glycol (PEG)-400. The developed approach of pretreatment by HA prior to application of clearing agents (PEG and PPG) resulted in a ˜47-fold increase in transmission of red and near-infrared light and significantly enhanced contrast of OA images.

  8. 3D imaging of cleared human skin biopsies using light-sheet microscopy: A new way to visualize in-depth skin structure.

    PubMed

    Abadie, S; Jardet, C; Colombelli, J; Chaput, B; David, A; Grolleau, J-L; Bedos, P; Lobjois, V; Descargues, P; Rouquette, J

    2018-05-01

    Human skin is composed of the superimposition of tissue layers of various thicknesses and components. Histological staining of skin sections is the benchmark approach to analyse the organization and integrity of human skin biopsies; however, this approach does not allow 3D tissue visualization. Alternatively, confocal or two-photon microscopy is an effective approach to perform fluorescent-based 3D imaging. However, owing to light scattering, these methods display limited light penetration in depth. The objectives of this study were therefore to combine optical clearing and light-sheet fluorescence microscopy (LSFM) to perform in-depth optical sectioning of 5 mm-thick human skin biopsies and generate 3D images of entire human skin biopsies. A benzyl alcohol and benzyl benzoate solution was used to successfully optically clear entire formalin fixed human skin biopsies, making them transparent. In-depth optical sectioning was performed with LSFM on the basis of tissue-autofluorescence observations. 3D image analysis of optical sections generated with LSFM was performed by using the Amira ® software. This new approach allowed us to observe in situ the different layers and compartments of human skin, such as the stratum corneum, the dermis and epidermal appendages. With this approach, we easily performed 3D reconstruction to visualise an entire human skin biopsy. Finally, we demonstrated that this method is useful to visualise and quantify histological anomalies, such as epidermal hyperplasia. The combination of optical clearing and LSFM has new applications in dermatology and dermatological research by allowing 3D visualization and analysis of whole human skin biopsies. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. Techniques for Solution- Assisted Optical Contacting

    NASA Technical Reports Server (NTRS)

    DeVine, Glenn; Ware, Brent; Wuchenich, Danielle M.; Spero, Robert E.; Klipstein, William M.; McKenzie, Kirk

    2012-01-01

    A document discusses a solution-assisted contacting technique for optical contacting. An optic of surface flatness Lambda/20 was successfully contacted with one of moderate surface quality, or Lambda/4. Optics used were both ultra-low expansion (ULE) glass (Lambda/4 and Lambda/20) and fused silica (Lambda/20). A stainless steel template of the intended interferometer layout was designed and constructed with three contact points per optic. The contact points were all on a common side of the template. The entire contacting jig was tilted at about 30 . Thus, when the isopropanol was applied, each optic slid due to gravity, resting on the contact points. All of the contacting was performed in a relatively dusty laboratory. A number of successful contacts were achieved where up to two or three visible pieces of dust could be seen. These were clearly visible due to refraction patterns between the optic and bench. On a number of optics, the final step of dropping isopropyl between the surfaces was repeated until a successful contact was achieved. The new procedures realized in this work represent a simplification for optical contacting in the laboratory. They will both save time and money spent during the contacting process, and research and development phases. The techniques outlined are suitable for laboratory experiments, research, and initial development stages.

  10. Blue-light digital communication in underwater environments utilizing orbital angular momentum

    NASA Astrophysics Data System (ADS)

    Baghdady, Joshua; Miller, Keith; Osler, Sean; Morgan, Kaitlyn; Li, Wenzhe; Johnson, Eric; Cochenour, Brandon

    2016-05-01

    Underwater optical communication has recently become the topic of much investigation as the demands for underwater data transmission have rapidly grown in recent years. The need for reliable, high-speed, secure underwater communication has turned increasingly to blue-light optical solutions. The blue-green visible wavelength window provides an attractive solution to the problem of underwater data transmission thanks to its low attenuation, where traditional RF solutions used in free-space communications collapse. Beginning with GaN laser diodes as the optical source, this work explores the encoding and transmission of digital data across underwater environments of varying turbidities. Given the challenges present in an underwater environment, such as the mechanical and optical turbulences that make proper alignment difficult to maintain, it is desirable to achieve extremely high data rates in order to allow the time window of alignment between the transmitter and receiver to be as small as possible. In this paper, work is done to increase underwater data rates through the use of orbital angular momentum. Results are shown for a range of data rates across a variety of channel types ranging in turbidity from that of a clear ocean to a dirty harbor.

  11. Backscattering from a Gaussian distributed, perfectly conducting, rough surface

    NASA Technical Reports Server (NTRS)

    Brown, G. S.

    1977-01-01

    The problem of scattering by random surfaces possessing many scales of roughness is analyzed. The approach is applicable to bistatic scattering from dielectric surfaces, however, this specific analysis is restricted to backscattering from a perfectly conducting surface in order to more clearly illustrate the method. The surface is assumed to be Gaussian distributed so that the surface height can be split into large and small scale components, relative to the electromagnetic wavelength. A first order perturbation approach is employed wherein the scattering solution for the large scale structure is perturbed by the small scale diffraction effects. The scattering from the large scale structure is treated via geometrical optics techniques. The effect of the large scale surface structure is shown to be equivalent to a convolution in k-space of the height spectrum with the following: the shadowing function, a polarization and surface slope dependent function, and a Gaussian factor resulting from the unperturbed geometrical optics solution. This solution provides a continuous transition between the near normal incidence geometrical optics and wide angle Bragg scattering results.

  12. Monitoring skin microvascular dysfunction of type 1 diabetic mice using in vivo skin optical clearing

    NASA Astrophysics Data System (ADS)

    Feng, Wei; Shi, Rui; Zhu, Dan

    2018-02-01

    To monitor skin microvascular dysfunction of alloxan-induced type 1 diabetic mice model. In this work, we used laser speckle contrast imaging and hyperspectral imaging through in vivo skin optical clearing method to simultaneously monitor the noradrenaline-induced response of microvascular blood flow and blood oxygen with the development of diabetes. The main results showed that venous and arterious blood flow steadily decreased without recovery after injecting noradrenaline (NE), furthermore the influence of NE-induced arterious blood oxygen response greatly decreased, especially for 2-weeks and 4-weeks diabetic mice. This study demonstrated that skin microvascular function was a potential research biomarker for early warning in the occurrence and development of diabetes. And it provides a feasible solution to realize visualization of cutaneous microvessels for monitoring microvascular reactivity.

  13. Fluorescence Diffusion in the Presence of Optically Clear Tissues in a Mouse Head Model.

    PubMed

    Ancora, Daniele; Zacharopoulos, Athanasios; Ripoll, Jorge; Zacharakis, Giannis

    2017-05-01

    Diffuse Optical Tomography commonly neglects or assumes as insignificant the presence of optically clear regions in biological tissues, estimating their contribution as a small perturbation to light transport. The inaccuracy introduced by this practice is examined in detail in the context of a complete, based on realistic geometry, virtual fluorescence Diffuse Optical Tomography experiment where a mouse head is imaged in the presence of cerebral spinal fluid. Despite the small thickness of such layer, we point out that an error is introduced when neglecting it from the model with possibly reduction in the accuracy of the reconstruction and localization of the fluorescence distribution within the brain. The results obtained in the extensive study presented here suggest that fluorescence diffuse neuroimaging studies can be improved in terms of quantitative and qualitative reconstruction by accurately taking into account optically transparent regions especially in the cases where the reconstruction is aided by the prior knowledge of the structural geometry of the specimen. Thus, this has only recently become an affordable choice, thanks to novel computation paradigms that allow to run Monte Carlo photon propagation on a simple graphic card, hence speeding up the process a thousand folds compared to CPU-based solutions.

  14. Solution of reduced graphene oxide synthesized from coconut shells and its optical properties

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mas’udah, Kusuma Wardhani, E-mail: masudahkusuma@ymail.com; Faculty of Mathematics and Natural Sciences, Univesitas Pesantren Tinggi Darul Ulum, PP. Darul ‘Ulum Tromol Pos 10 Peterongan Jombang 61481; Nugraha, I Made Ananta, E-mail: anantanugraha25@gmail.com

    Reduced graphene oxide (r-GO)powder has been prepared from coconut shells by carbonization process at 400°C for 3, 4 and 5 hours.Theresulted sample mass was reduced to be 60% relativelycompared to the starting material. The longer heating duration has also led to the rGO with reduced crystalinity according to the X-ray diffractometry data and TEM. The rGO solution was prepared by adding powders of 5, 10 and 15 grams into 50 ml destiled water and then centrifused at 6000 rpm for 30 minutes.The resulted solutions were seen to be varied form clear transparant, light and dark yellow to black. Measurement using particle sizemore » analyser shows that the individual rGO particles tends to be agglomerating each others to form bigger size clustering, manifested by the observed bigger size particles for the increasing amount of soluted rGO powders in water.The varying UV-visible spectra of these rGO solutions together with their optical bandgaps will also be discussed in this study.« less

  15. Optical properties of mouse brain tissue after optical clearing with FocusClear™

    NASA Astrophysics Data System (ADS)

    Moy, Austin J.; Capulong, Bernard V.; Saager, Rolf B.; Wiersma, Matthew P.; Lo, Patrick C.; Durkin, Anthony J.; Choi, Bernard

    2015-09-01

    Fluorescence microscopy is commonly used to investigate disease progression in biological tissues. Biological tissues, however, are strongly scattering in the visible wavelengths, limiting the application of fluorescence microscopy to superficial (<200 μm) regions. Optical clearing, which involves incubation of the tissue in a chemical bath, reduces the optical scattering in tissue, resulting in increased tissue transparency and optical imaging depth. The goal of this study was to determine the time- and wavelength-resolved dynamics of the optical scattering properties of rodent brain after optical clearing with FocusClear™. Light transmittance and reflectance of 1-mm mouse brain sections were measured using an integrating sphere before and after optical clearing and the inverse adding doubling algorithm used to determine tissue optical scattering. The degree of optical clearing was quantified by calculating the optical clearing potential (OCP), and the effects of differing OCP were demonstrated using the optical histology method, which combines tissue optical clearing with optical imaging to visualize the microvasculature. We observed increased tissue transparency with longer optical clearing time and an analogous increase in OCP. Furthermore, OCP did not vary substantially between 400 and 1000 nm for increasing optical clearing durations, suggesting that optical histology can improve ex vivo visualization of several fluorescent probes.

  16. FBG in PVC foils for monitoring the knee joint movement during the rehabilitation process.

    PubMed

    Rocha, R P; Silva, A F; Carmo, J P; Correia, J H

    2011-01-01

    This paper presents a sensing electronic-free wearable solution for monitoring the body kinematics. The measuring of the knee movements, flexion and extension, with the corresponding joint acting as the rotation axis is shown as working principle. The proposed sensing system is based on a single optical Fiber-Bragg Grating (FBG) with a resonance wavelength of 1547.76 nm. The optical fiber with the FBG is placed inside a new polymeric foil composed by three flexible layers which facilitates its placement in the anatomic parts under investigation while maintaining full sensing capabilities. The way the device is placed in the specific body part to be measured enables the clear detection of the movements in respect to the joint. The proposed solution was tested using a prototype that was built to evaluate the device under different condition tests and also to assess the system's consistency. The designed and fabricated system demonstrates clear advantages in medical fields like physical therapy applications as optical fiber is not affected by electromagnetic interference nor does the system needs complex and expensive electronic systems and mechanical parts. Another advantage is the possibility to measure, record and evaluate specific mechanical parameters of the limbs' motion. Patients with bone, muscular and joint related health conditions, as well as athletes, are within the most important end-user applications.

  17. Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping.

    PubMed

    Treweek, Jennifer B; Chan, Ken Y; Flytzanis, Nicholas C; Yang, Bin; Deverman, Benjamin E; Greenbaum, Alon; Lignell, Antti; Xiao, Cheng; Cai, Long; Ladinsky, Mark S; Bjorkman, Pamela J; Fowlkes, Charless C; Gradinaru, Viviana

    2015-11-01

    To facilitate fine-scale phenotyping of whole specimens, we describe here a set of tissue fixation-embedding, detergent-clearing and staining protocols that can be used to transform excised organs and whole organisms into optically transparent samples within 1-2 weeks without compromising their cellular architecture or endogenous fluorescence. PACT (passive CLARITY technique) and PARS (perfusion-assisted agent release in situ) use tissue-hydrogel hybrids to stabilize tissue biomolecules during selective lipid extraction, resulting in enhanced clearing efficiency and sample integrity. Furthermore, the macromolecule permeability of PACT- and PARS-processed tissue hybrids supports the diffusion of immunolabels throughout intact tissue, whereas RIMS (refractive index matching solution) grants high-resolution imaging at depth by further reducing light scattering in cleared and uncleared samples alike. These methods are adaptable to difficult-to-image tissues, such as bone (PACT-deCAL), and to magnified single-cell visualization (ePACT). Together, these protocols and solutions enable phenotyping of subcellular components and tracing cellular connectivity in intact biological networks.

  18. ClearSee: a rapid optical clearing reagent for whole-plant fluorescence imaging

    PubMed Central

    Kurihara, Daisuke; Mizuta, Yoko; Sato, Yoshikatsu; Higashiyama, Tetsuya

    2015-01-01

    Imaging techniques for visualizing and analyzing precise morphology and gene expression patterns are essential for understanding biological processes during development in all organisms. With the aid of chemical screening, we developed a clearing method using chemical solutions, termed ClearSee, for deep imaging of morphology and gene expression in plant tissues. ClearSee rapidly diminishes chlorophyll autofluorescence while maintaining fluorescent protein stability. By adjusting the refractive index mismatch, whole-organ and whole-plant imaging can be performed by both confocal and two-photon excitation microscopy in ClearSee-treated samples. Moreover, ClearSee is applicable to multicolor imaging of fluorescent proteins to allow structural analysis of multiple gene expression. Given that ClearSee is compatible with staining by chemical dyes, the technique is useful for deep imaging in conjunction with genetic markers and for plant species not amenable to transgenic approaches. This method is useful for whole imaging for intact morphology and will help to accelerate the discovery of new phenomena in plant biological research. PMID:26493404

  19. Optics vs copper: from the perspective of "Thunderbolt" interconnect technology

    NASA Astrophysics Data System (ADS)

    Cheng, Hengju; Krause, Christine; Ko, Jamyuen; Gao, Miaobin; Liu, Guobin; Wu, Huichin; Qi, Mike; Lam, Chun-Chit

    2013-02-01

    Interconnect technology has been progressed at a very fast pace for the past decade. The signaling rates have steadily increased from 100:Mb/s to 25Gb/s. In every generation of interconnect technology evolution, optics always seems to take over at first, however, at the end, the cost advantage of copper wins over. Because of this, optical interconnects are limited to longer distance links where the attenuation in copper cable is too large for the integrated circuits to compensate. Optical interconnect has long been viewed as the premier solution in compared with copper interconnect. With the release of Thunderbolt technology, we are entering a new era in consumer electronics that runs at 10Gb/s line rate (20Gb/s throughput per connector interface). Thunderbolt interconnect technology includes both active copper cables and active optical cables as the transmission media which have very different physical characteristics. In order for optics to succeed in consumer electronics, several technology hurdles need to be cleared. For example, the optical cable needs to handle the consumer abuses such as pinch and bend. Also, the optical engine used in the active optical cable needs to be physically very small so that we don't change the looks and feels of the cable/connector. Most importantly, the cost of optics needs to come down significantly to effectively compete with the copper solution. Two interconnect technologies are compared and discussed on the relative cost, power consumption, form factor, density, and future scalability.

  20. Femtosecond dynamics in hydrogen-bonded solvents

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Castner, E.W. Jr.; Chang, Y.J.

    1993-09-01

    We present results on the ultrafast dynamics of pure hydrogen-bonding solvents, obtained using femtosecond Fourier-transform optical-heterodyne-detected, Raman-induced Kerr effect spectroscopy. Solvent systems we have studied include the formamides, water, ethylene glycol, and acetic acid. Inertial and diffusive motions are clearly resolved. We comment on the effect that such ultrafast solvent motions have on chemical reactions in solution.

  1. Effects of optical clearing agents on noninvasive blood glucose monitoring with optical coherence tomography: a pilot study

    NASA Astrophysics Data System (ADS)

    He, Ruoyu; Wei, Huajiang; Gu, Huimin; Zhu, Zhengguo; Zhang, Yuqing; Guo, Xiao; Cai, Tiantian

    2012-10-01

    Recently, the capability of optical coherence tomography (OCT) has been demonstrated for noninvasive blood glucose monitoring. In this work, we investigate the administration of chemical agents onto human skin tissue to increase the transparency of the surface of the skin, as a means of improving the capability of OCT imaging for clinically relevant applications. Eight groups of experiments were proposed, in which different optical clearing agents (OCA) were used. The results indicate that, when properly used, some OCAs perform well in promoting the capability of OCT for noninvasive blood glucose monitoring. Among the four kinds of OCA we used, 50% v/v glycerol solute turns out to be the best enhancer. Compared with the results of the experiments in which no OCA was used, when 50% glycerol was applied onto the human skin topically, the correlation coefficient between the OCT signal slope (OCTSS) and blood glucose concentration (BGC) was improved by 7.1% on average, and the lag time between changes in the OCTSS and BGC was cut by 8 min on average. The results of 10 w/v mannitol were also good, but not as pronounced.

  2. Microstructured optical fiber Bragg grating sensor for DNA detection

    NASA Astrophysics Data System (ADS)

    Candiani, A.; Giannetti, S.; Sozzi, M.; Coscelli, E.; Poli, F.; Cucinotta, A.; Bertucci, A.; Corradini, R.; Konstantaki, M.; Margulis, W.; Pissadakis, S.; Selleri, S.

    2013-03-01

    In this work the inner surface of a microstructured optical fiber, where a Bragg grating was previously inscribed, has been functionalized using peptide nucleic acid probe targeting a DNA sequence of the cystic fibrosis disease. The solution of DNA molecules, matched with the PNA probes, has been infiltrated inside the fiber capillaries and hybridization has been realized according to the Watson - Crick Model. In order to achieve signal amplification, oligonucleotide-functionalized gold nanoparticles were then infiltrated and used to form a sandwich-like system. Experimental measurements show a clear wavelength shift of the reflected high order mode for a 100 nM DNA solution. Several experiments have been carried out on the same fiber using the identical concentration, showing the same modulation and proving a good reproducibility of the results, suggesting the possibility of the reuse of the sensor. Measurements have been also made using a 100 nM mis-matched DNA solution, containing a single nucleotide polymorphism, demonstrating the high selectivity of the sensor.

  3. Observations of the Geometry of Horizon-Based Optical Navigation

    NASA Technical Reports Server (NTRS)

    Christian, John; Robinson, Shane

    2016-01-01

    NASA's Orion Project has sparked a renewed interest in horizon-based optical navigation(OPNAV) techniques for spacecraft in the Earth-Moon system. Some approaches have begun to explore the geometry of horizon-based OPNAV and exploit the fact that it is a conic section problem. Therefore, the present paper focuses more deeply on understanding and leveraging the various geometric interpretations of horizon-based OPNAV. These results provide valuable insight into the fundamental workings of OPNAV solution methods, their convergence properties, and associated estimate covariance. Most importantly, the geometry and transformations uncovered in this paper lead to a simple and non-iterative solution to the generic horizon-based OPNAV problem. This represents a significant theoretical advancement over existing methods. Thus, we find that a clear understanding of geometric relationships is central to the prudent design, use, and operation of horizon-based OPNAV techniques.

  4. Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing.

    PubMed

    Chen, Dongsheng; Zeng, Nan; Xie, Qiaolin; He, Honghui; Tuchin, Valery V; Ma, Hui

    2017-08-01

    We investigate the polarization features corresponding to changes in the microstructure of nude mouse skin during immersion in a glycerol solution. By comparing the Mueller matrix imaging experiments and Monte Carlo simulations, we examine in detail how the Mueller matrix elements vary with the immersion time. The results indicate that the polarization features represented by Mueller matrix elements m22&m33&m44 and the absolute values of m34&m43 are sensitive to the immersion time. To gain a deeper insight on how the microstructures of the skin vary during the tissue optical clearing (TOC), we set up a sphere-cylinder birefringence model (SCBM) of the skin and carry on simulations corresponding to different TOC mechanisms. The good agreement between the experimental and simulated results confirm that Mueller matrix imaging combined with Monte Carlo simulation is potentially a powerful tool for revealing microscopic features of biological tissues.

  5. The next generation in optical transport semiconductors: IC solutions at the system level

    NASA Astrophysics Data System (ADS)

    Gomatam, Badri N.

    2005-02-01

    In this tutorial overview, we survey some of the challenging problems facing Optical Transport and their solutions using new semiconductor-based technologies. Advances in 0.13um CMOS, SiGe/HBT and InP/HBT IC process technologies and mixed-signal design strategies are the fundamental breakthroughs that have made these solutions possible. In combination with innovative packaging and transponder/transceiver architectures IC approaches have clearly demonstrated enhanced optical link budgets with simultaneously lower (perhaps the lowest to date) cost and manufacturability tradeoffs. This paper will describe: *Electronic Dispersion Compensation broadly viewed as the overcoming of dispersion based limits to OC-192 links and extending link budgets, *Error Control/Coding also known as Forward Error Correction (FEC), *Adaptive Receivers for signal quality monitoring for real-time estimation of Q/OSNR, eye-pattern, signal BER and related temporal statistics (such as jitter). We will discuss the theoretical underpinnings of these receiver and transmitter architectures, provide examples of system performance and conclude with general market trends. These Physical layer IC solutions represent a fundamental new toolbox of options for equipment designers in addressing systems level problems. With unmatched cost and yield/performance tradeoffs, it is expected that IC approaches will provide significant flexibility in turn, for carriers and service providers who must ultimately manage the network and assure acceptable quality of service under stringent cost constraints.

  6. Skin optical clearing potential of disaccharides

    NASA Astrophysics Data System (ADS)

    Feng, Wei; Shi, Rui; Ma, Ning; Tuchina, Daria K.; Tuchin, Valery V.; Zhu, Dan

    2016-08-01

    Skin optical clearing can significantly enhance the ability of biomedical optical imaging. Some alcohols and sugars have been selected to be optical clearing agents (OCAs). In this work, we paid attention to the optical clearing potential of disaccharides. Sucrose and maltose were chosen as typical disaccharides to compare with fructose, an excellent monosaccharide-OCA, by using molecular dynamics simulation and an ex vivo experiment. The experimental results indicated that the optical clearing efficacy of skin increases linearly with the concentration for each OCA. Both the theoretical predication and experimental results revealed that the two disaccharides exerted a better optical clearing potential than fructose at the same concentration, and sucrose is optimal. Since maltose has an extremely low saturation concentration, the other two OCAs with saturation concentrations were treated topically on rat skin in vivo, and optical coherence tomography imaging was applied to monitor the optical clearing process. The results demonstrated that sucrose could cause a more significant increase in imaging depth and signal intensity than fructose.

  7. Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping

    PubMed Central

    Treweek, Jennifer B; Deverman, Benjamin E; Greenbaum, Alon; Lignell, Antti; Xiao, Cheng; Cai, Long; Ladinsky, Mark S; Bjorkman, Pamela J; Fowlkes, Charless C; Gradinaru, Viviana

    2016-01-01

    To facilitate fine-scale phenotyping of whole specimens, we describe here a set of tissue fixation-embedding, detergent-clearing and staining protocols that can be used to transform excised organs and whole organisms into optically transparent samples within 1–2 weeks without compromising their cellular architecture or endogenous fluorescence. PACT (passive CLARITY technique) and PARS (perfusion-assisted agent release in situ) use tissue-hydrogel hybrids to stabilize tissue biomolecules during selective lipid extraction, resulting in enhanced clearing efficiency and sample integrity. Furthermore, the macromolecule permeability of PACT- and PARS-processed tissue hybrids supports the diffusion of immunolabels throughout intact tissue, whereas RIMS (refractive index matching solution) grants high-resolution imaging at depth by further reducing light scattering in cleared and uncleared samples alike. These methods are adaptable to difficult-to-image tissues, such as bone (PACT-deCAL), and to magnified single-cell visualization (ePACT). Together, these protocols and solutions enable phenotyping of subcellular components and tracing cellular connectivity in intact biological networks. PMID:26492141

  8. Optical interconnects for satellite payloads: overview of the state-of-the-art

    NASA Astrophysics Data System (ADS)

    Vervaeke, Michael; Debaes, Christof; Van Erps, Jürgen; Karppinen, Mikko; Tanskanen, Antti; Aalto, Timo; Harjanne, Mikko; Thienpont, Hugo

    2010-05-01

    The increased demand of broadband communication services like High Definition Television, Video On Demand, Triple Play, fuels the technologies to enhance the bandwidth of individual users towards service providers and hence the increase of aggregate bandwidths on terrestial networks. Optical solutions clearly leverage the bandwidth appetite easily whereas electrical interconnection schemes require an ever-increasing effort to counteract signal distortions at higher bitrates. Dense wavelength division multiplexing and all-optical signal regeneration and switching solve the bandwidth demands of network trunks. Fiber-to-the-home, and fiber-to-the-desk are trends towards providing individual users with greatly increased bandwidth. Operators in the satellite telecommunication sector face similar challenges fuelled by the same demands as for their terrestial counterparts. Moreover, the limited number of orbital positions for new satellites set the trend for an increase in payload datacommunication capacity using an ever-increasing number of complex multi-beam active antennas and a larger aggregate bandwidth. Only satellites with very large capacity, high computational density and flexible, transparent fully digital payload solutions achieve affordable communication prices. To keep pace with the bandwidth and flexibility requirements, designers have to come up with systems requiring a total digital througput of a few Tb/s resulting in a high power consuming satellite payload. An estimated 90 % of the total power consumption per chip is used for the off-chip communication lines. We have undertaken a study to assess the viability of optical datacommunication solutions to alleviate the demands regarding power consumption and aggregate bandwidth imposed on future satellite communication payloads. The review on optical interconnects given here is especially focussed on the demands of the satellite communication business and the particular environment in which the optics have to perform their functionality: space.

  9. Absorbance enhancement in microplate wells for improved-sensitivity biosensors.

    PubMed

    Suárez, Guillaume; Santschi, Christian; Plateel, Gregory; Martin, Olivier J F; Riediker, Michael

    2014-06-15

    A generic optical biosensing strategy was developed that relies on the absorbance enhancement phenomenon occurring in a multiple scattering matrix. Experimentally, inserts made of glass fiber membrane were placed into microplate wells in order to significantly lengthen the trajectory of the incident light through the sample and therefore increase the corresponding absorbance. Enhancement factor was calculated by comparing the absorbance values measured for a given amount of dye with and without the absorbance-enhancing inserts in the wells. Moreover, the dilution of dye in solutions with different refractive indices (RI) clearly revealed that the enhancement factor increased with the ΔRI between the membrane and the surrounding medium, reaching a maximum value (EF>25) when the membranes were dried. On this basis, two H2O2-biosensing systems were developed based on the biofunctionalization of the glass fiber inserts either with cytochrome c or horseradish peroxidase (HRP) and the analytical performances were systematically compared with the corresponding bioassay in solution. The efficiency of the absorbance-enhancement approach was particularly clear in the case of the cytochrome c-based biosensor with a sensitivity gain of 40 folds and wider dynamic range. Therefore, the developed strategy represents a promising way to convert standard colorimetric bioassays into optical biosensors with improved sensitivity. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Monitoring of itaconic acid hydrogenation in a trickle bed reactor using fiber-optic coupled near-infrared spectroscopy.

    PubMed

    Wood, Joseph; Turner, Paul H

    2003-03-01

    Near-infrared (NIR) spectroscopy has been applied to determine the conversion of itaconic acid in the effluent stream of a trickle bed reactor. Hydrogenation of itaconic to methyl succinic acid was carried out, with the trickle bed operating in recycle mode. For the first time, NIR spectra of itaconic and methyl succinic acids in aqueous solution, and aqueous mixtures withdrawn from the reactor over a range of reaction times, have been recorded using a fiberoptic sampling probe. The infrared spectra displayed a clear isolated absorption band at a wavenumber of 6186 cm(-1) (wavelength 1.617 microm) resulting from the =C-H bonds of itaconic acid, which was found to decrease in intensity with increasing reaction time. The feature could be more clearly observed from plots of the first derivatives of the spectra. A partial least-squares (PLS) model was developed from the spectra of 13 reference samples and was used successfully to calculate the concentration of the two acids in the reactor effluent solution. Itaconic acid conversions of 23-29% were calculated after 360 min of reaction time. The potential of FT-NIR with fiber-optic sampling for remote monitoring of three-phase catalytic reactors and validation of catalytic reactor models is highlighted in the paper.

  11. A very demanding spectrometer optical design for ExoMars Mission

    NASA Astrophysics Data System (ADS)

    Belenguer, T.; Fernandez-Rodriguez, M.; Colombo, M.; Diaz-Catalá, E.; Sanchez-Páramo, J.

    2017-11-01

    The objective of this report is to present the study performed for a specially demanding solution of a spectrometer [1] design based on a transmissive holographic grating especially designed to actuate as the dispersion element. The main driver of the design has been to obtain a device with a clear reduction in mass, power and mechanical envelope with respect to the previous configuration based on a prism and/or Echelle grating. This simplification is produced mainly at expense of the waveband range. This study has been carried out by Laboratorio de Instrumentación Espacial (LINES) optical designers from Instituto Nacional de Técnica Aeroespacial (INTA).

  12. Synthesis of non-hydrazine solution processed Cu2(ZnSn)S4 thin films for solar cells applications

    NASA Astrophysics Data System (ADS)

    Gupta, Indu; Gupta, Preeti; Mohanty, Bhaskar Chandra

    2017-05-01

    Solution processing provides a versatile and inexpensive means to prepare Cu2ZnSnS4 (CZTS) thin films for photovoltaic applications. Differently with the reported growth of CZTS films from hydrazine based toxic solutions, we demonstrate a simple non-toxic ethanol based solution approach to synthesize the films. Using the chemical bath deposition (CBD) method, the CZTS thin films were grown from metal salts (copper chloride, zinc chloride, and tin chloride) in ethanol and monoethanol amine (MEA) and thioacetamide in ethanol as sulfur source in a single dip followed by sulfurization. The structure, composition, morphology and optical properties of the CZTS film were studied by X-ray diffraction, scanning electron microscopy and UV-vis spectroscopy. The results revealed that a post-deposition sulfurization is necessary to the phase formation and among all, sulfurization at 450°C for 60 min yielded phase pure CZTS films having kesterite structure, relatively compact morphology and an optical band gap of ˜1.52 eV indicating its suitability for solar cell applications. The results clearly validate the CBD method as a potential scalable route of preparation of CZTS thin films.

  13. A versatile new technique to clear mouse and human brain

    NASA Astrophysics Data System (ADS)

    Costantini, Irene; Di Giovanna, Antonino Paolo; Allegra Mascaro, Anna Letizia; Silvestri, Ludovico; Müllenbroich, Marie Caroline; Sacconi, Leonardo; Pavone, Francesco S.

    2015-07-01

    Large volumes imaging with microscopic resolution is limited by light scattering. In the last few years based on refractive index matching, different clearing approaches have been developed. Organic solvents and water-based optical clearing agents have been used for optical clearing of entire mouse brain. Although these methods guarantee high transparency and preservation of the fluorescence, though present other non-negligible limitations. Tissue transformation by CLARITY allows high transparency, whole brain immunolabelling and structural and molecular preservation. This method however requires a highly expensive refractive index matching solution limiting practical applicability. In this work we investigate the effectiveness of a water-soluble clearing agent, the 2,2'-thiodiethanol (TDE) to clear mouse and human brain. TDE does not quench the fluorescence signal, is compatible with immunostaining and does not introduce any deformation at sub-cellular level. The not viscous nature of the TDE make it a suitable agent to perform brain slicing during serial two-photon (STP) tomography. In fact, by improving penetration depth it reduces tissue slicing, decreasing the acquisition time and cutting artefacts. TDE can also be used as a refractive index medium for CLARITY. The potential of this method has been explored by imaging a whole transgenic mouse brain with the light sheet microscope. Moreover we apply this technique also on blocks of dysplastic human brain tissue transformed with CLARITY and labeled with different antibody. This clearing approach significantly expands the application of single and two-photon imaging, providing a new useful method for quantitative morphological analysis of structure in mouse and human brain.

  14. Use of an UROV to develop 3-D optical models of submarine environments

    NASA Astrophysics Data System (ADS)

    Null, W. D.; Landry, B. J.

    2017-12-01

    The ability to rapidly obtain high-fidelity bathymetry is crucial for a broad range of engineering, scientific, and defense applications ranging from bridge scour, bedform morphodynamics, and coral reef health to unexploded ordnance detection and monitoring. The present work introduces the use of an Underwater Remotely Operated Vehicle (UROV) to develop 3-D optical models of submarine environments. The UROV used a Raspberry Pi camera mounted to a small servo which allowed for pitch control. Prior to video data collection, in situ camera calibration was conducted with the system. Multiple image frames were extracted from the underwater video for 3D reconstruction using Structure from Motion (SFM). This system provides a simple and cost effective solution to obtaining detailed bathymetry in optically clear submarine environments.

  15. A Semianalytical Ocean Color Inversion Algorithm with Explicit Water Column Depth and Substrate Reflectance Parameterization

    NASA Technical Reports Server (NTRS)

    Mckinna, Lachlan I. W.; Werdell, P. Jeremy; Fearns, Peter R. C.; Weeks, Scarla J.; Reichstetter, Martina; Franz, Bryan A.; Shea, Donald M.; Feldman, Gene C.

    2015-01-01

    A semianalytical ocean color inversion algorithm was developed for improving retrievals of inherent optical properties (IOPs) in optically shallow waters. In clear, geometrically shallow waters, light reflected off the seafloor can contribute to the water-leaving radiance signal. This can have a confounding effect on ocean color algorithms developed for optically deep waters, leading to an overestimation of IOPs. The algorithm described here, the Shallow Water Inversion Model (SWIM), uses pre-existing knowledge of bathymetry and benthic substrate brightness to account for optically shallow effects. SWIM was incorporated into the NASA Ocean Biology Processing Group's L2GEN code and tested in waters of the Great Barrier Reef, Australia, using the Moderate Resolution Imaging Spectroradiometer (MODIS) Aqua time series (2002-2013). SWIM-derived values of the total non-water absorption coefficient at 443 nm, at(443), the particulate backscattering coefficient at 443 nm, bbp(443), and the diffuse attenuation coefficient at 488 nm, Kd(488), were compared with values derived using the Generalized Inherent Optical Properties algorithm (GIOP) and the Quasi-Analytical Algorithm (QAA). The results indicated that in clear, optically shallow waters SWIM-derived values of at(443), bbp(443), and Kd(443) were realistically lower than values derived using GIOP and QAA, in agreement with radiative transfer modeling. This signified that the benthic reflectance correction was performing as expected. However, in more optically complex waters, SWIM had difficulty converging to a solution, a likely consequence of internal IOP parameterizations. Whilst a comprehensive study of the SWIM algorithm's behavior was conducted, further work is needed to validate the algorithm using in situ data.

  16. Optical clearing of the eye using the See Deep Brain technique.

    PubMed

    Hohberger, B; Baumgart, C; Bergua, A

    2017-10-01

    PurposeTissue clearing has been used in anatomy for the first time in Germany over a century ago. Neuronal tissue, like cortex, was investigated in mice using a water-based optical clearing method termed See Deep Brain (SeeDB). However, although the eye belongs to the central nervous system, this histological technique was not applied in the eye up to date. We applied SeeDB for the visualization of intraocular structures.Patients and methodsFour eyes of cornea donors (two male, two female: 73-84 years) obtained from the Cornea Bank of the Department of Ophthalmology Erlangen, four chicken eyes and two mices' optic nerve were used. Bulbi were fixed in 4% paraformaldehyde in phosphate-buffered saline and treated with increasing concentrations of aqueous fructose solution with 0.5% α-thioglycerol. After SeeDB, transscleral macrophotographs of the choroid were performed.ResultsComplete transparency of the sclera was obtained in enucleated human and chicken eyes after SeeDB treatment. Macroscopical anatomy of the choroid (partially transparent due to the remaining retinal pigment epithelium and melanocytes) showing vessels and other related structures was possible without preparing slides. Mice optic nerves were also transparent after SeeDB treatment.ConclusionThe SeeDB method allows visualization of intraocular structures through a completely translucent sclera. This innovative processing technique could facilitate comprehensive qualitative and quantitative topographical anatomical studies of human and animal eyes, preserving their 3D architecture. Supra- and intrachoroidal ganglionic plexus could potentially be visualized transsclerally. Finally, clinical-pathological correlations of intraocular diseases-for example, retinal tumors-will be possible in non-dissected eyes.

  17. Morphology Development in Solution-Processed Functional Organic Blend Films: An In Situ Viewpoint.

    PubMed

    Richter, Lee J; DeLongchamp, Dean M; Amassian, Aram

    2017-05-10

    Solution-processed organic films are a facile route to high-speed, low cost, large-area deposition of electrically functional components (transistors, solar cells, emitters, etc.) that can enable a diversity of emerging technologies, from Industry 4.0, to the Internet of things, to point-of-use heath care and elder care. The extreme sensitivity of the functional performance of organic films to structure and the general nonequilibrium nature of solution drying result in extreme processing-performance correlations. In this Review, we highlight insights into the fundamentals of solution-based film deposition afforded by recent state-of-the-art in situ measurements of functional film drying. Emphasis is placed on multimodal studies that combine surface-sensitive X-ray scattering (GIWAXS or GISAXS) with optical characterization to clearly define the evolution of solute structure (aggregation, crystallinity, and morphology) with film thickness.

  18. Optical clearing for luminal organ imaging with ultrahigh-resolution optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Liang, Yanmei; Yuan, Wu; Mavadia-Shukla, Jessica; Li, Xingde

    2016-08-01

    The imaging depth of optical coherence tomography (OCT) in highly scattering biological tissues (such as luminal organs) is limited, particularly for OCT operating at shorter wavelength regions (such as around 800 nm). For the first time, the optical clearing effect of the mixture of liquid paraffin and glycerol on luminal organs was explored with ultrahigh-resolution spectral domain OCT at 800 nm. Ex vivo studies were performed on pig esophagus and bronchus, and guinea pig esophagus with different volume ratios of the mixture. We found that the mixture of 40% liquid paraffin had the best optical clearing effect on esophageal tissues with a short effective time of ˜10 min, which means the clearing effect occurs about 10 min after the application of the clearing agent. In contrast, no obvious optical clearing effect was identified on bronchus tissues.

  19. Study of the inhibition effect of thiazone on muscle optical clearing

    NASA Astrophysics Data System (ADS)

    Jin, Xiaowei; Deng, Zhichao; Wang, Jin; Ye, Qing; Mei, Jianchun; Zhou, Wenyuan; Zhang, Chunping; Tian, Jianguo

    2016-10-01

    We investigated the effect of thiazone, a widely used penetration enhancer, on in vitro porcine skin and muscle tissue by single-integrating sphere technique during optical clearing (OC) treatment. The results showed that thiazone induced an increase on the total transmittance of skin which led to a reduction in that of muscle in the spectral range from 400 to 800 nm. Small particles crystalized out from the thiazone-treated muscle were observed by microscopy imaging. With the help of x-ray diffraction measurement, we ascertained that the crystal was a single-crystal of thiazone, which mainly induced an increase of the scattering. Contrast transmittance measurements carried on the mixture of water, thizaone-propylene glycol solution showed that the free water in muscle could be the main reason for the thiazone crystallization. Therefore, during OC treatment of thiazone, the remarkable effect on skin and the noticeable inhibition effect on subcutaneous muscle tissue after penetrating into the skin should be considered. The experimental results provide such a reference for the choice of penetration enhancer.

  20. Atmospheric propagation characteristics of highest importance to commercial free space optics

    NASA Astrophysics Data System (ADS)

    Korevaar, Eric J.; Kim, Isaac I.; McArthur, Bruce

    2003-04-01

    There is a certain amount of disconnect between the perception and reality of Free Space Optics (FSO), both in the marketplace and in the technical community. In the marketplace, the requirement for FSO technology has not grown to even a fraction of the levels predicted a few years ago. In the technical community, proposed solutions for the limitations of FSO continue to miss the mark. The main commercial limitation for FSO is that light does not propagate very far in dense fog, which occurs a non-negligible amount of the time. There is no known solution for this problem (other than using microwave or other modality backup systems), and therefore FSO equipment has to be priced very competitively to sell in a marketplace dominated by copper wire, fiber optic cabling and increasingly lower cost and higher bandwidth wireless microwave equipment. Expensive technologies such as adaptive optics, which could potentially increase equipment range in clear weather, do not justify the added cost when expected bad weather conditions are taken into account. In this paper we present a simple equation to fit average data for probability of exceeding different atmospheric attenuation values. This average attenuation equation is then used to compare the expected availability performance as a function of link distance for representative FSO systems of different cost.

  1. Misalignment corrections in optical interconnects

    NASA Astrophysics Data System (ADS)

    Song, Deqiang

    Optical interconnects are considered a promising solution for long distance and high bitrate data transmissions, outperforming electrical interconnects in terms of loss and dispersion. Due to the bandwidth and distance advantage of optical interconnects, longer links have been implemented with optics. Recent studies show that optical interconnects have clear advantages even at very short distances---intra system interconnects. The biggest challenge for such optical interconnects is the alignment tolerance. Many free space optical components require very precise assembly and installation, and therefore the overall cost could be increased. This thesis studied the misalignment tolerance and possible alignment correction solutions for optical interconnects at backplane or board level. First the alignment tolerance for free space couplers was simulated and the result indicated the most critical alignments occur between the VCSEL, waveguide and microlens arrays. An in-situ microlens array fabrication method was designed and experimentally demonstrated, with no observable misalignment with the waveguide array. At the receiver side, conical lens arrays were proposed to replace simple microlens arrays for a larger angular alignment tolerance. Multilayer simulation models in CodeV were built to optimized the refractive index and shape profiles of the conical lens arrays. Conical lenses fabricated with micro injection molding machine and fiber etching were characterized. Active component VCSOA was used to correct misalignment in optical connectors between the board and backplane. The alignment correction capability were characterized for both DC and AC (1GHz) optical signal. The speed and bandwidth of the VCSOA was measured and compared with a same structure VCSEL. Based on the optical inverter being studied in our lab, an all-optical flip-flop was demonstrated using a pair of VCSOAs. This memory cell with random access ability can store one bit optical signal with set or reset beam. The operating conditions were studied to generate two stable states between the VCSOA pair. The entire functionality test was implemented with free space optical components.

  2. A large, switchable optical clearing skull window for cerebrovascular imaging

    PubMed Central

    Zhang, Chao; Feng, Wei; Zhao, Yanjie; Yu, Tingting; Li, Pengcheng; Xu, Tonghui; Luo, Qingming; Zhu, Dan

    2018-01-01

    Rationale: Intravital optical imaging is a significant method for investigating cerebrovascular structure and function. However, its imaging contrast and depth are limited by the turbid skull. Tissue optical clearing has a great potential for solving this problem. Our goal was to develop a transparent skull window, without performing a craniotomy, for use in assessing cerebrovascular structure and function. Methods: Skull optical clearing agents were topically applied to the skulls of mice to create a transparent window within 15 min. The clearing efficacy, repeatability, and safety of the skull window were then investigated. Results: Imaging through the optical clearing skull window enhanced both the contrast and the depth of intravital imaging. The skull window could be used on 2-8-month-old mice and could be expanded from regional to bi-hemispheric. In addition, the window could be repeatedly established without inducing observable inflammation and metabolic toxicity. Conclusion: We successfully developed an easy-to-handle, large, switchable, and safe optical clearing skull window. Combined with various optical imaging techniques, cerebrovascular structure and function can be observed through this optical clearing skull window. Thus, it has the potential for use in basic research on the physiopathologic processes of cortical vessels. PMID:29774069

  3. Monte Carlo study of skin optical clearing to enhance light penetration in the tissue: implications for photodynamic therapy of acne vulgaris

    NASA Astrophysics Data System (ADS)

    Bashkatov, Alexey N.; Genina, Elina A.; Tuchin, Valery V.; Altshuler, Gregory B.; Yaroslavsky, Ilya V.

    2008-06-01

    Result of Monte Carlo simulations of skin optical clearing is presented. The model calculations were carried out with the aim of studying of spectral response of skin under immersion liquids action and calculation of enhancement of light penetration depth. In summary, we have shown that: 1) application of glucose, propylene glycol and glycerol produced significant decrease of light scattering in different skin layers; 2) maximal clearing effect will be obtained in case of optical clearing of skin dermis, however, absorbed light fraction in skin dermis changed insignificantly, independently on clearing agent and place it administration; 3) in contrast to it, the light absorbed fraction in skin adipose layer increased significantly in case of optical clearing of skin dermis. It is very important because it can be used for development of optical methods of obesity treatment; 4) optical clearing of superficial skin layers can be used for decreasing of power of light radiation used for treatment of acne vulgaris.

  4. Photodeposition of amorphous polydiacetylene films from monomer solutions onto transparent substrates

    NASA Technical Reports Server (NTRS)

    Paley, M. S.; Frazier, D. O.; Abdeldeyem, H.; Armstrong, S.; McManus, S. P.

    1995-01-01

    Polydiacetylenes are a very promising class of polymers for both photonic and electronic applications because of their highly conjugated structures. For these applications, high-quality thin polydiacetylene films are required. We have discovered a novel technique for obtaining such films of a polydiacetylene derivative of 2-methyl-4-nitroaniline using photodeposition from monomer solutions onto UV transparent substrates. This heretofore unreported process yields amorphous polydiacetylene films with thicknesses on the order of I micron that have optical quality superior to that of films grown by standard crystal growth techniques. Furthermore, these films exhibit good third-order nonlinear optical susceptibilities; degenerate four-wave mixing experiments give x(3) values on the order of 10(exp -8) - 10(exp -7) esu. We have conducted masking experiments which demonstrate that photodeposition occurs only where the substrate is directly irradiated, clearly indicating that the reaction occurs at the surface. Additionally, we have also been able to carry out photodeposition using lasers to form thin polymer circuits. In this work, we discuss the photodeposition of polydiacetylene thin films from solution, perform chemical characterization of these films, investigate the role of the substrate, speculate on the mechanism of the reaction, and make a preliminary determination of the third-order optical nonlinearity of the films. This simple, straightforward technique may ultimately make feasible the production of polydiacetylene thin films for technological applications.

  5. Dwell-time algorithm for polishing large optics.

    PubMed

    Wang, Chunjin; Yang, Wei; Wang, Zhenzhong; Yang, Xu; Hu, Chenlin; Zhong, Bo; Guo, Yinbiao; Xu, Qiao

    2014-07-20

    The calculation of the dwell time plays a crucial role in polishing precision large optics. Although some studies have taken place, it remains a challenge to develop a calculation algorithm which is absolutely stable, together with a high convergence ratio and fast solution speed even for extremely large mirrors. For this aim, we introduced a self-adaptive iterative algorithm to calculate the dwell time in this paper. Simulations were conducted in bonnet polishing (BP) to test the performance of this method on a real 430  mm × 430  mm fused silica part with the initial surface error PV=1741.29  nm, RMS=433.204  nm. The final surface residual error in the clear aperture after two simulation steps turned out to be PV=11.7  nm, RMS=0.5  nm. The results confirm that this method is stable and has a high convergence ratio and fast solution speed even with an ordinary computer. It is notable that the solution time is usually just a few seconds even on a 1000  mm × 1000  mm part. Hence, we believe that this method is perfectly suitable for polishing large optics. And not only can it be applied to BP, but it can also be applied to other subaperture deterministic polishing processes.

  6. Core-based intrinsic fiber-optic absorption sensor for the detection of volatile organic compounds

    NASA Astrophysics Data System (ADS)

    Klunder, Gregory L.; Russo, Richard E.

    1995-03-01

    A core-based intrinsic fiber-optic absorption sensor has been developed and tested for the detection of volatile organic compounds. The distal ends of transmitting and receiving fibers are connected by a small cylindrical section of an optically clear silicone rubber. The silicone rubber acts both as a light pipe and as a selective membrane into which the analyte molecules can diffuse. The sensor has been used to detect volatile organics (trichloroethylene, 1,1-dichloroethylene, and benzene) in both aqueous solutions and in the vapor phase or headspace. Absorption spectra obtained in the near-infrared (near-IR) provide qualitative and quantitative information about the analyte. Water, which has strong broad-band absorption in the near-IR, is excluded from the spectra because of the hydrophobic properties of the silicone rubber. The rate-limiting step is shown to be the diffusion through the Nernstian boundary layer surrounding the sensor and not the diffusion through the silicone polymer. The rate of analyte diffusion into the sensor, as measured by the t(sub 90) values (the time required for the sensor to reach 90% of the equilibrium value), is 30 min for measurements in aqueous solutions and approximately 3 min for measurements made in the headspace. The limit of detection obtained with this sensor is approximately 1.1 ppm for trichloroethylene in an aqueous solution.

  7. Seeing through Musculoskeletal Tissues: Improving In Situ Imaging of Bone and the Lacunar Canalicular System through Optical Clearing

    PubMed Central

    Berke, Ian M.; Miola, Joseph P.; David, Michael A.; Smith, Melanie K.; Price, Christopher

    2016-01-01

    In situ, cells of the musculoskeletal system reside within complex and often interconnected 3-D environments. Key to better understanding how 3-D tissue and cellular environments regulate musculoskeletal physiology, homeostasis, and health is the use of robust methodologies for directly visualizing cell-cell and cell-matrix architecture in situ. However, the use of standard optical imaging techniques is often of limited utility in deep imaging of intact musculoskeletal tissues due to the highly scattering nature of biological tissues. Drawing inspiration from recent developments in the deep-tissue imaging field, we describe the application of immersion based optical clearing techniques, which utilize the principle of refractive index (RI) matching between the clearing/mounting media and tissue under observation, to improve the deep, in situ imaging of musculoskeletal tissues. To date, few optical clearing techniques have been applied specifically to musculoskeletal tissues, and a systematic comparison of the clearing ability of optical clearing agents in musculoskeletal tissues has yet to be fully demonstrated. In this study we tested the ability of eight different aqueous and non-aqueous clearing agents, with RIs ranging from 1.45 to 1.56, to optically clear murine knee joints and cortical bone. We demonstrated and quantified the ability of these optical clearing agents to clear musculoskeletal tissues and improve both macro- and micro-scale imaging of musculoskeletal tissue across several imaging modalities (stereomicroscopy, spectroscopy, and one-, and two-photon confocal microscopy) and investigational techniques (dynamic bone labeling and en bloc tissue staining). Based upon these findings we believe that optical clearing, in combination with advanced imaging techniques, has the potential to complement classical musculoskeletal analysis techniques; opening the door for improved in situ investigation and quantification of musculoskeletal tissues. PMID:26930293

  8. Seeing through Musculoskeletal Tissues: Improving In Situ Imaging of Bone and the Lacunar Canalicular System through Optical Clearing.

    PubMed

    Berke, Ian M; Miola, Joseph P; David, Michael A; Smith, Melanie K; Price, Christopher

    2016-01-01

    In situ, cells of the musculoskeletal system reside within complex and often interconnected 3-D environments. Key to better understanding how 3-D tissue and cellular environments regulate musculoskeletal physiology, homeostasis, and health is the use of robust methodologies for directly visualizing cell-cell and cell-matrix architecture in situ. However, the use of standard optical imaging techniques is often of limited utility in deep imaging of intact musculoskeletal tissues due to the highly scattering nature of biological tissues. Drawing inspiration from recent developments in the deep-tissue imaging field, we describe the application of immersion based optical clearing techniques, which utilize the principle of refractive index (RI) matching between the clearing/mounting media and tissue under observation, to improve the deep, in situ imaging of musculoskeletal tissues. To date, few optical clearing techniques have been applied specifically to musculoskeletal tissues, and a systematic comparison of the clearing ability of optical clearing agents in musculoskeletal tissues has yet to be fully demonstrated. In this study we tested the ability of eight different aqueous and non-aqueous clearing agents, with RIs ranging from 1.45 to 1.56, to optically clear murine knee joints and cortical bone. We demonstrated and quantified the ability of these optical clearing agents to clear musculoskeletal tissues and improve both macro- and micro-scale imaging of musculoskeletal tissue across several imaging modalities (stereomicroscopy, spectroscopy, and one-, and two-photon confocal microscopy) and investigational techniques (dynamic bone labeling and en bloc tissue staining). Based upon these findings we believe that optical clearing, in combination with advanced imaging techniques, has the potential to complement classical musculoskeletal analysis techniques; opening the door for improved in situ investigation and quantification of musculoskeletal tissues.

  9. Stiffness of RBC optical confinement affected by optical clearing

    NASA Astrophysics Data System (ADS)

    Grishin, Oleg V.; Fedosov, Ivan V.; Tuchin, Valery V.

    2017-03-01

    In vivo optical trapping is a novel applied direction of an optical manipulation, which enables one to noninvasive measurement of mechanical properties of cells and tissues in living animals directly. But an application area of this direction is limited because strong scattering of many biological tissues. An optical clearing enables one to decrease the scattering and therefore increase a depth of light penetration, decrease a distortion of light beam, improve a resolution in imaging applications. Now novel methods had appeared for a measurement an optical clearing degree at a cellular level. But these methods aren't applicable in vivo. In this paper we present novel measurement method of estimate of the optical clearing, which are based on a measurement of optical trap stiffness. Our method may be applicable in vivo.

  10. The morphological changes of optically cleared cochlea using optical coherence tomography (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Lee, Jaeyul; Song, Jaewon; Jeon, Mansik; Kim, Jeehyun

    2017-02-01

    In this study, we monitored the optical clearing effects by immersing ex vivo guinea pig cochlea samples in ethylenediaminetetraacetic acid (EDTA) to study the internal microstructures in the morphology of guinea pig cochlea. The imaging limitations due to the guinea pig cochlea structures were overcome by optical clearing technique. Subsequently, the study was carried out to confirm the required approximate immersing duration of cochlea in EDTA-based optical clearing to obtain the best optimal depth visibility for guinea pig cochlea samples. Thus, we implemented a decalcification-based optical clearing effect to guinea pig cochlea samples to enhance the depth visualization of internal microstructures using swept source optical coherence tomography (OCT). The obtained nondestructive two-dimensional OCT images successfully illustrated the feasibility of the proposed method by providing clearly visible microstructures in the depth direction as a result of decalcification. The most optimal clearing outcomes for the guinea pig cochlea were obtained after 14 consecutive days. The quantitative assessment results verified the increase of the intensity as well as the thickness measurements of the internal microstructures. Following this method, difficulties in imaging of internal cochlea microstructures of guinea pigs could be avoided. The obtained results verified that the depth visibility of the decalcified ex vivo guinea pig cochlea samples was enhanced. Therefore, the proposed EDTA-based optical clearing method for guinea pig can be considered as a potential application for depth-enhanced OCT visualization.

  11. Prediction of optical communication link availability: real-time observation of cloud patterns using a ground-based thermal infrared camera

    NASA Astrophysics Data System (ADS)

    Bertin, Clément; Cros, Sylvain; Saint-Antonin, Laurent; Schmutz, Nicolas

    2015-10-01

    The growing demand for high-speed broadband communications with low orbital or geostationary satellites is a major challenge. Using an optical link at 1.55 μm is an advantageous solution which potentially can increase the satellite throughput by a factor 10. Nevertheless, cloud cover is an obstacle for this optical frequency. Such communication requires an innovative management system to optimize the optical link availability between a satellite and several Optical Ground Stations (OGS). The Saint-Exupery Technological Research Institute (France) leads the project ALBS (French acronym for BroadBand Satellite Access). This initiative involving small and medium enterprises, industrial groups and research institutions specialized in aeronautics and space industries, is currently developing various solutions to increase the telecommunication satellite bandwidth. This paper presents the development of a preliminary prediction system preventing the cloud blockage of an optical link between a satellite and a given OGS. An infrared thermal camera continuously observes (night and day) the sky vault. Cloud patterns are observed and classified several times a minute. The impact of the detected clouds on the optical beam (obstruction or not) is determined by the retrieval of the cloud optical depth at the wavelength of communication. This retrieval is based on realistic cloud-modelling on libRadtran. Then, using subsequent images, cloud speed and trajectory are estimated. Cloud blockage over an OGS can then be forecast up to 30 minutes ahead. With this information, the preparation of the new link between the satellite and another OGS under a clear sky can be prepared before the link breaks due to cloud blockage.

  12. DNA biosensors implemented on PNA-functionalized microstructured optical fibers Bragg gratings

    NASA Astrophysics Data System (ADS)

    Candiani, A.; Giannetti, S.; Cucinotta, A.; Bertucci, A.; Manicardi, A.; Konstantaki, M.; Margulis, W.; Pissadakis, S.; Corradini, R.; Selleri, S.

    2013-05-01

    A novel DNA sensing platform based on a Peptide Nucleic Acid - functionalized Microstructured Optical Fibers gratings has been demonstrated. The inner surface of different MOFs has been functionalized using PNA probes, OligoNucleotides mimic that are well suited for specific DNA target sequences detection. The hybrid sensing systems were tested for optical DNA detection of targets of relevance in biomedical application, using the cystic fibrosis gene mutation, and food-analysis, using the genomic DNA from genetic modified organism soy flour. After the solutions of DNA molecules has been infiltrated inside the fibers capillaries and hybridization has occurred, oligonucleotidefunctionalized gold nanoparticles were infiltrated and used to form a sandwich-like system to achieve signal amplification. Spectral measurements of the reflected signal reveal a clear wavelength shift of the reflected modes when the infiltrated complementary DNA matches with the PNA probes placed on the inner fiber surface. Measurements have also been made using the mismatched DNA solution for the c, containing a single nucleotide polymorphism, showing no significant changes in the reflected spectrum. Several experiments have been carried out demonstrating the reproducibility of the results and the high selectivity of the sensors, showing the simplicity and the potential of this approach.

  13. Light Extraction From Solution-Based Processable Electrophosphorescent Organic Light-Emitting Diodes

    NASA Astrophysics Data System (ADS)

    Krummacher, Benjamin C.; Mathai, Mathew; So, Franky; Choulis, Stelios; Choong, And-En, Vi

    2007-06-01

    Molecular dye dispersed solution processable blue emitting organic light-emitting devices have been fabricated and the resulting devices exhibit efficiency as high as 25 cd/A. With down-conversion phosphors, white emitting devices have been demonstrated with peak efficiency of 38 cd/A and luminous efficiency of 25 lm/W. The high efficiencies have been a product of proper tuning of carrier transport, optimization of the location of the carrier recombination zone and, hence, microcavity effect, efficient down-conversion from blue to white light, and scattering/isotropic remission due to phosphor particles. An optical model has been developed to investigate all these effects. In contrast to the common misunderstanding that light out-coupling efficiency is about 22% and independent of device architecture, our device data and optical modeling results clearly demonstrated that the light out-coupling efficiency is strongly dependent on the exact location of the recombination zone. Estimating the device internal quantum efficiencies based on external quantum efficiencies without considering the device architecture could lead to erroneous conclusions.

  14. Skull optical clearing for assessing to cerebral hemodynamics with high contrast and resolution (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Zhu, Dan

    2017-03-01

    The tissue optical clearing technique could significantly enhance the biomedical optical imaging depth, but current investigations are mainly limited to in vitro studies. In vivo tissue optical clearing method should be enough rapid, transparent and safe, which makes it more difficult, especially, for hard tissue. During the past years, we developed skull optical clearing methods for in vivo cortical imaging. This presentation will report recent progress in skull optical clearing method, including their efficacy, safety, and applications. The skull optical clearing method is proved to be effective for adult mice ages in different month and permit various imaging techniques to monitor cortical blood flow, blood oxygen, and vascular with high resolution and contrast, not only for local cortex, but also for whole cortex. The long-term and short-term observation show that there is no obvious effect on cortical vascular function when laser speckle contrast imaging and hyperspectral imaging are used to repeatedly image the cortical blood flow, blood oxygen. Finally, we will demonstrate some applications for physiological or pathological situation, including monitoring the anoxia, drug-induced cortical response, et al.

  15. A uniform geometrical optics and an extended uniform geometrical theory of diffraction for evaluating high frequency EM fields near smooth caustics and composite shadow boundaries

    NASA Technical Reports Server (NTRS)

    Constantinides, E. D.; Marhefka, R. J.

    1994-01-01

    A uniform geometrical optics (UGO) and an extended uniform geometrical theory of diffraction (EUTD) are developed for evaluating high frequency electromagnetic (EM) fields within transition regions associated with a two and three dimensional smooth caustic of reflected rays and a composite shadow boundary formed by the caustic termination or the confluence of the caustic with the reflection shadow boundary (RSB). The UGO is a uniform version of the classic geometrical optics (GO). It retains the simple ray optical expressions of classic GO and employs a new set of uniform reflection coefficients. The UGO also includes a uniform version of the complex GO ray field that exists on the dark side of the smooth caustic. The EUTD is an extension of the classic uniform geometrical theory of diffraction (UTD) and accounts for the non-ray optical behavior of the UGO reflected field near caustics by using a two-variable transition function in the expressions for the edge diffraction coefficients. It also uniformly recovers the classic UTD behavior of the edge diffracted field outside the composite shadow boundary transition region. The approach employed for constructing the UGO/EUTD solution is based on a spatial domain physical optics (PO) radiation integral representation for the fields which is then reduced using uniform asymptotic procedures. The UGO/EUTD analysis is also employed to investigate the far-zone RCS problem of plane wave scattering from two and three dimensional polynomial defined surfaces, and uniform reflection, zero-curvature, and edge diffraction coefficients are derived. Numerical results for the scattering and diffraction from cubic and fourth order polynomial strips are also shown and the UGO/EUTD solution is validated by comparison to an independent moment method (MM) solution. The UGO/EUTD solution is also compared with the classic GO/UTD solution. The failure of the classic techniques near caustics and composite shadow boundaries is clearly demonstrated and it is shown that the UGO/EUTD results remain valid and uniformly reduce to the classic results away from the transition regions. Mathematical details on the asymptotic properties and efficient numerical evaluation of the canonical functions involved in the UGO/EUTD expressions are also provided.

  16. SU-G-IeP4-08: Initial Investigations of Up-Converting Nanoparticles (UCNP) for 3D Tissue Imaging in Optical-ECT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yoon, S; Dewhirst, M; Oldham, M

    Purpose: Near-IR absorptive up-converting nanoparticles (UCNPs) is a novel contrast for optical-ECT that allows auto-fluorescence-free 3D imaging of labeled cells in a matrix of large (∼1cm{sup 3}) unsectioned normal tissue. This has the potential to image small metastases or dormant cells that is difficult with down-converting fluorescing dyes due to auto-fluorescence. The feasibility of imaging UCNP in agarose phantoms and a mouse lung is demonstrated, aided by a 3D-printed optical-ECT stage designed to excite UCNP in a mouse lung. Methods: The UCNP, NaYF{sub 4}:Yb/Er (20/2%), studied in this work up-converts 980nm light to visible light peaking sharply at ∼540nm. Tomore » characterize the UCNP emission as a function of UCNP concentration, cylindrical 2.5%wt agarose phantoms infused with UCNP at concentrations of 25µg/mL and 50µg/mL were exposed to 1.5W 980nm laser coupled to an optical fiber. The fiber was held stably at 1cm above the stage via a custom 3D-printed stage. An optically cleared lung harvested from a BALBc mice was then injected with 100µL of 1mg/mL UCNP solution ex vivo. Tomographic imaging of the UCNP emission in lung was performed. Results: The laser beam tract is visualized within the agarose phantom. A line profile of UCNP emission at 25µg/mL versus 50µg/mL shows that increasing the UCNP concentration increases emission count. UCNPs injected into a cleared mouse lung disperse throughout the respiratory tract, allowing for visualization and 3D reconstruction. Excitation before and after UCNP injection shows the tissue exhibits no auto-fluorescence at 980nm, allowing clear view of the UCNP without any obscuring features such as conventional down-converting fluorescent tags. Conclusion: We confirm that up-conversion in tissue circumvents completely tissue auto-fluorescence, which allowed background-free 3D reconstruction of the UCNP distribution. We also confirm that raising the UCNP concentration increases emission and that UCNPs are retained in agarose samples during the optical clearing process.« less

  17. TH-EF-207A-06: High-Resolution Optical-CT/ECT Imaging of Unstained Mice Femur, Brain, Spleen, and Tumor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yoon, S; Dewhirst, M; Oldham, M

    2016-06-15

    Purpose: Optical transmission and emission computed tomography (optical-CT/ECT) provides high-resolution 3D attenuation and emission maps in unsectioned large (∼1cm{sup 3}) ex vivo tissue samples at a resolution of 12.9µm{sup 3} per voxel. Here we apply optical-CT/ECT to investigate high-resolution structure and auto-fluorescence in a range of optically cleared mice organs, including, for the first time, mouse bone (femur), opening the potential for study of bone metastasis and bone-mediated immune response. Methods: Three BALBc mice containing 4T1 flank tumors were sacrificed to obtain spleen, brain, tumor, and femur. Tissues were washed in 4% PFA, fixed in EtOH solution (for 5, 10,more » 10, and 2 days respectively), and then optically cleared for 3 days in BABBs. The femur was also placed in 0.25M aqueous EDTA for 15–30 days to remove calcium. Optical-CT/ECT attenuation and emission maps at 633nm (the latter using 530nm excitation light) were obtained for all samples. Bi-telecentric optical-CT was compared side-by-side with conventional optical projection tomography (OPT) imaging to evaluate imaging capability of these two rival techniques. Results: Auto-fluorescence mapping of femurs reveals vasculatures and fluorescence heterogeneity. High signals (A.U.=10) are reported in the medullary cavity but not in the cortical bone (A.U.=1). The brain strongly and uniform auto-fluoresces (A.U.=5). Thick, optically dense organs such as the spleen and the tumor (0.12, 0.46OD/mm) are reconstructed at depth without significant loss of resolution, which we attribute to the bi-telecentric optics of optical-CT. The attenuation map of tumor reveals vasculature, attenuation heterogeneity, and possibly necrotic tissue. Conclusion: We demonstrate the feasibility of optical-CT/ECT imaging of un-sectioned mice bones (femurs) and spleen with high resolution. This result, and the characterization of unstained organs, are important steps enabling future studies involving optical-CT/ECT applied to study metastasis and immunologic responses via fluorescence staining.« less

  18. A new sol-gel processing routine without chelating agents for preparing highly transparent solutions and nanothin films: engineering the role of chemistry to design the process

    NASA Astrophysics Data System (ADS)

    Ashiri, Rouholah

    2015-01-01

    The great sensitivity of titanium alkoxides to hydrolysis makes their sol-gel transformation very fast and thus difficult to control. A method was proposed to alleviate this drawback. Preparation of highly transparent solutions and nanothin films is another objective of the present research. Employing nanoemulsion method and optimizing the processing conditions, a clear solution of well-dispersed nanosized particles was obtained. With the proposed process BaTiO3 precursor sols and nanothin films with enhanced optical transparency towards the visible were prepared. The optimal formulation of the sol consists of acetic acid, barium acetate, 2-propanol, TTIP and deionized water with 6:1:1:1:150 M ratios, respectively. It was found that the reduction of the temperature in the initial stage of mixing of precursors controls the size of the forming species and accordingly improves the stability and transparency of the sol. The results also showed that the applied modifications and optimizations significantly downsize the particles within the sol to the nanometric scale and accordingly result in a significant improvement in the optical response of the products.

  19. Hybrid scheduling mechanisms for Next-generation Passive Optical Networks based on network coding

    NASA Astrophysics Data System (ADS)

    Zhao, Jijun; Bai, Wei; Liu, Xin; Feng, Nan; Maier, Martin

    2014-10-01

    Network coding (NC) integrated into Passive Optical Networks (PONs) is regarded as a promising solution to achieve higher throughput and energy efficiency. To efficiently support multimedia traffic under this new transmission mode, novel NC-based hybrid scheduling mechanisms for Next-generation PONs (NG-PONs) including energy management, time slot management, resource allocation, and Quality-of-Service (QoS) scheduling are proposed in this paper. First, we design an energy-saving scheme that is based on Bidirectional Centric Scheduling (BCS) to reduce the energy consumption of both the Optical Line Terminal (OLT) and Optical Network Units (ONUs). Next, we propose an intra-ONU scheduling and an inter-ONU scheduling scheme, which takes NC into account to support service differentiation and QoS assurance. The presented simulation results show that BCS achieves higher energy efficiency under low traffic loads, clearly outperforming the alternative NC-based Upstream Centric Scheduling (UCS) scheme. Furthermore, BCS is shown to provide better QoS assurance.

  20. Morphology and pH changes in leached solidified/stabilized waste forms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cheng, K.Y.; Bishop, P.L.

    1996-12-31

    Leaching of cement-based waste forms in acetic acid solutions with different acidic strengths has been investigated in this work. The examination of the morphology and pH profile along the acid penetration route by an optical microscope and various pH color indicators is reported. A clear-cut leaching boundary, where the pH changes from below 6 in the leached surface layers to above 12 in the unleached waste form, was observed in every leached sample.

  1. Optical coherence tomography based imaging of dental demineralisation and cavity restoration in 840 nm and 1310 nm wavelength regions

    NASA Astrophysics Data System (ADS)

    Damodaran, Vani; Rao, Suresh Ranga; Vasa, Nilesh J.

    2016-08-01

    In this paper, a study of in-house built optical coherence tomography (OCT) system with a wavelength of 840 nm for imaging of dental caries, progress in demineralisation and cavity restoration is presented. The caries when imaged with the 840 nm OCT system showed minute demineralisation in the order of 5 μm. The OCT system was also proposed to study the growth of lesion and this was demonstrated by artificially inducing caries with a demineralisation solution of pH 4.8. The progress of carious lesion to a depth of about 50-60 μm after 60 hours of demineralisation was clearly observed with the 840 nm OCT system. The tooth samples were subjected to accelerated demineralisation condition at pH of approximately 2.3 to study the adverse effects and the onset of cavity formation was clearly observed. The restoration of cavity was also studied by employing different restorative materials (filled and unfilled). In the case of restoration without filler material (unfilled), the restoration boundaries were clearly observed. Overall, results were comparable with that of the widely used 1310 nm OCT system. In the case of restoration with filler material, the 1310 nm OCT imaging displayed better imaging capacity due to lower scattering than 840 nm imaging.

  2. Ring-Gaussian laser pulse filamentation in a self-induced diffraction waveguide

    NASA Astrophysics Data System (ADS)

    Geints, Yu E.; Zemlyanov, A. A.

    2017-10-01

    Self-action in air of a high-power femtosecond laser pulse with the spatial form of a ring-Gaussian beam (‘dressed’ beam) is studied theoretically. Pulse self-focusing and filamentation is analyzed in detail through the numerical solution of the spectral propagation equation, taking into account medium optical nonlinearity and plasma generation. Pulse propagation dynamics and energy fluxes inside the beam are visualized by means of averaged diffraction ray tracing. We clearly show that, in terms of diffraction optics, the outer ring forms a specific nonmaterial diffractive waveguide, favoring long-range self-channeling of the central part of a beam by delivering optical energy to a filament. The spatial robustness and stability of such diffractive waveguides strongly depends on the energy stored in the ring, as well as on its position relative to the beam axis. The striking advantage of such ‘dressed’ beams is their reduced angular divergence during plasma-free (post-filamentation) evolution.

  3. Room temperature three-photon pumped CH3NH3PbBr3 perovskite microlasers.

    PubMed

    Gao, Yisheng; Wang, Shuai; Huang, Can; Yi, Ningbo; Wang, Kaiyang; Xiao, Shumin; Song, Qinghai

    2017-03-28

    Hybrid lead halide perovskites have made great strides in next-generation light-harvesting and light emitting devices. Recently, they have also shown great potentials in nonlinear optical materials. Two-photon absorption and two-photon light emission have been thoroughly studied in past two years. However, the three-photon processes are rarely explored, especially for the laser emissions. Here we synthesized high quality CH 3 NH 3 PbBr 3 perovskite microstructures with solution processed precipitation method and studied their optical properties. When the microstructures are pumped with intense 1240 nm lasers, we have observed clear optical limit effect and the band-to-band photoluminescence at 540 nm. By increasing the pumping density, whispering-gallery-mode based microlasers have been achieved from CH 3 NH 3 PbBr 3 perovskite microplate and microrod for the first time. This work demonstrates the potentials of hybrid lead halide perovskites in nonlinear photonic devices.

  4. Room temperature three-photon pumped CH3NH3PbBr3 perovskite microlasers

    NASA Astrophysics Data System (ADS)

    Gao, Yisheng; Wang, Shuai; Huang, Can; Yi, Ningbo; Wang, Kaiyang; Xiao, Shumin; Song, Qinghai

    2017-03-01

    Hybrid lead halide perovskites have made great strides in next-generation light-harvesting and light emitting devices. Recently, they have also shown great potentials in nonlinear optical materials. Two-photon absorption and two-photon light emission have been thoroughly studied in past two years. However, the three-photon processes are rarely explored, especially for the laser emissions. Here we synthesized high quality CH3NH3PbBr3 perovskite microstructures with solution processed precipitation method and studied their optical properties. When the microstructures are pumped with intense 1240 nm lasers, we have observed clear optical limit effect and the band-to-band photoluminescence at 540 nm. By increasing the pumping density, whispering-gallery-mode based microlasers have been achieved from CH3NH3PbBr3 perovskite microplate and microrod for the first time. This work demonstrates the potentials of hybrid lead halide perovskites in nonlinear photonic devices.

  5. A circadian rhythm in optic nerve impulses from an isolated eye in darkness.

    NASA Technical Reports Server (NTRS)

    Jacklet, J. W.

    1971-01-01

    Study of the circadian rhythm of optic nerve potentials recorded from the isolated eye of the sea hare Aplysia. The optic nerve activity in constant conditions is found to be clearly circadian and to obey the circadian rule for diurnal animals. In addition, the period length depends on the in vitro culturing solution. In seawater it is about 22 hr, but in culture medium it is 27 hr. The rhythm can be completely phase-shifted in one trial if the phase of the LD 12:12 Zeitgeber is advanced or delayed 4 hr. The rhythm in one eye can be phase-shifted in vivo independently of the other eye and in vitro independently of the rest of the animal. Thus, in the animal, the eye oscillators are, at most, only slightly influenced by each other or by other oscillators in the animal.

  6. Advanced optical 3D scanners using DMD technology

    NASA Astrophysics Data System (ADS)

    Muenstermann, P.; Godding, R.; Hermstein, M.

    2017-02-01

    Optical 3D measurement techniques are state-of-the-art for highly precise, non-contact surface scanners - not only in industrial development, but also in near-production and even in-line configurations. The need for automated systems with very high accuracy and clear implementation of national precision standards is growing extremely due to expanding international quality guidelines, increasing production transparency and new concepts related to the demands of the fourth industrial revolution. The presentation gives an overview about the present technical concepts for optical 3D scanners and their benefit for customers and various different applications - not only in quality control, but also in design centers or in medical applications. The advantages of DMD-based systems will be discussed and compared to other approaches. Looking at today's 3D scanner market, there is a confusing amount of solutions varying from lowprice solutions to high end systems. Many of them are linked to a very special target group or to special applications. The article will clarify the differences of the approaches and will discuss some key features which are necessary to render optical measurement systems suitable for industrial environments. The paper will be completed by examples for DMDbased systems, e. g. RGB true-color systems with very high accuracy like the StereoScan neo of AICON 3D Systems. Typical applications and the benefits for customers using such systems are described.

  7. Hollow optical-fiber based infrared spectroscopy for measurement of blood glucose level by using multi-reflection prism.

    PubMed

    Kino, Saiko; Omori, Suguru; Katagiri, Takashi; Matsuura, Yuji

    2016-02-01

    A mid-infrared attenuated total reflection (ATR) spectroscopy system employing hollow optical fibers and a trapezoidal multi-reflection ATR prism has been developed to measure blood glucose levels. Using a multi-reflection prism brought about higher sensitivity, and the flat and wide contact surface of the prism resulted in higher measurement reproducibility. An analysis of in vivo measurements of human inner lip mucosa revealed clear signatures of glucose in the difference spectra between ones taken during the fasting state and ones taken after ingestion of glucose solutions. A calibration plot based on the absorption peak at 1155 cm(-1) that originates from the pyranose ring structure of glucose gave measurement errors less than 20%.

  8. In situ control of industrial processes using laser light scattering and optical rotation

    NASA Astrophysics Data System (ADS)

    Mendoza Sanchez, Patricia Judith; López Echevarria, Daniel; Huerta Ruelas, Jorge Adalberto

    2006-02-01

    We present results of optical measurements in products or processes usually found in industrial processes, which can be used to control them. Laser light scattering was employed during semiconductor epitaxial growth by molecular beam epitaxy. With this technique, it was possible to determine growth rate, roughness and critical temperatures related to substrate degradation. With the same scattering technique, oil degradation as function of temperature was monitored for different automotive lubricants. Clear differences can be studied between monograde and multigrade oils. Optical rotation measurements as function of temperature were performed in apple juice in a pasteurization process like. Average variations related to optical rotation dependence of sugars were measured and monitored during heating and cooling process, finding a reversible behavior. As opposite behavior, sugar-protein solution was measured in a similar heating and cooling process. Final result showed a non-reversible behavior related to protein denaturation. Potential applications are discussed for metal-mechanic, electronic, food, and pharmaceutical industry. Future improvements in optical systems to make them more portable and easily implemented under typical industry conditions are mentioned.

  9. Structural and optical characterization of PVA:KMnO4 based solid polymer electrolyte

    NASA Astrophysics Data System (ADS)

    Abdullah, Omed Gh.; Aziz, Shujahadeen B.; Rasheed, Mariwan A.

    Solid polymer electrolyte films of polyvinyl alcohol (PVA) doped with a different weight percent of potassium permanganate (KMnO4) were prepared by standard solution cast method. XRD and FTIR techniques were performed for structural study. Complex formation between the PVA polymer and KMnO4 salt was confirmed by Fourier transform infrared (FTIR) spectroscopy. The description of crystalline nature of the solid polymer electrolyte films has been confirmed by XRD analysis. The UV-Visible absorption spectra were analyzed in terms of absorption formula for non-crystalline materials. The fundamental optical parameters such as optical band gap energy, refractive index, optical conductivity, and dielectric constants have been investigated and showed a clear dependence on the KMnO4 concentration. The observed value of optical band gap energy for pure PVA is about 6.27 eV and decreases to a value 3.12 eV for the film sample formed with 4 wt% KMnO4 salt. The calculated values of refractive index and the dielectric constants of the polymer electrolyte films increase with increasing KMnO4 content.

  10. Study of the epidermis ablation effect on the efficiency of optical clearing of skin in vivo

    NASA Astrophysics Data System (ADS)

    Genina, E. A.; Ksenofontova, N. S.; Bashkatov, A. N.; Terentyuk, G. S.; Tuchin, V. V.

    2017-06-01

    We present the results of a comparative analysis of optical immersion clearing of skin in laboratory animals in vivo with and without preliminary ablation of epidermis. Laser ablation is implemented using a setup based on a pulsed erbium laser (λ = 2940 nm). The size of the damaged region amounted to 6 × 6 mm, the depth being smaller than 50 μm. As an optical clearing agent (OCA), use is made of polyethylene glycol (PEG-300). Based on optical coherence tomography, we use the single scattering model to estimate the scattering coefficient in the process of optical clearing in 2 regions at depths of 50-170 μm and 150-400 μm. The results show that skin surface ablation leads to the local oedema of the affected region that increases the scattering coefficient. However, the intense evaporation of water from the ablation zone facilitates the optical clearing at the expense of tissue dehydration, particularly in the upper layers. The assessment of the optical clearing efficiency shows that the efficiency exceeding 30% can be achieved at a depth from 50 to 170 μm in 120 min after ablation, as well as after the same ablation with subsequent application of PEG-300, which increases the efficiency of the immersion method by almost 1.8 times. At a depth from 150 to 400 μm, dehydration of upper layers cannot completely compensate for an increase in light scattering by dermis after epidermis ablation. The additional effect of OCA enhances the optical clearing of skin at the expense of improving the refractive index matching between dermis components, but the maximal efficiency of optical clearing in 120 min does not exceed 6%.

  11. 77 FR 34445 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Outsourcing Solutions, Inc. as an NYSE Arca ETP Holder and OTP Holder, Subject to Apex Clearing Complying With... Corporation, f/k/a Ridge Clearing and Outsourcing Solutions, Inc. (``Apex Clearing'') as an NYSE Arca ETP... Clearing & Outsourcing Solutions, Inc. Prior to the transaction, Ridge Clearing & Outsourcing Solutions...

  12. Enhanced optical clearing of skin in vivo and optical coherence tomography in-depth imaging

    NASA Astrophysics Data System (ADS)

    Wen, Xiang; Jacques, Steven L.; Tuchin, Valery V.; Zhu, Dan

    2012-06-01

    The strong optical scattering of skin tissue makes it very difficult for optical coherence tomography (OCT) to achieve deep imaging in skin. Significant optical clearing of in vivo rat skin sites was achieved within 15 min by topical application of an optical clearing agent PEG-400, a chemical enhancer (thiazone or propanediol), and physical massage. Only when all three components were applied together could a 15 min treatment achieve a three fold increase in the OCT reflectance from a 300 μm depth and 31% enhancement in image depth Zthreshold.

  13. 77 FR 34442 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Clearing and Outsourcing Solutions, Inc. as an Exchange Equities Member Organization and ATP Holder... Apex Clearing Corporation, f/k/a Ridge Clearing and Outsourcing Solutions, Inc. (``Apex Clearing'') as... to the Transaction, Apex Clearing's name was Ridge Clearing & Outsourcing Solutions, Inc. Prior to...

  14. 77 FR 34450 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Ridge Clearing and Outsourcing Solutions, Inc. as an NYSE Member Organization, Subject to Apex Clearing... order to approve Apex Clearing Corporation, f/ k/a Ridge Clearing and Outsourcing Solutions, Inc... Transaction, Apex Clearing's name was Ridge Clearing & Outsourcing Solutions, Inc. Prior to the transaction...

  15. New optical museum at Saint-Petersburg for education and training

    NASA Astrophysics Data System (ADS)

    Vasil'ev, V. N.; Stafeef, S. K.; Tomilin, M. G.

    2009-06-01

    Nowadays the educational problem of teaching optics and photonics is to attract the young generation to the wonderful and magic world of light, optical science, technology and systems. The main issue is to explain that in the course of last several hundred years optics has been representing the most clear world view for humanity. In fact, the optics itself is a multidisciplinary complex of independent scientific directions, and, moreover, it has always been a generator of new fields of knowledge. Besides, optics and photonics are the fields within which the most fundamental problems of today's reality are to be resolved. It is absolutely necessary to encourage our scholars in getting optics and photonics education as an alternative physical basis to gaining solely computer knowledge. The main obstacle is the poor connection between program of optical education and the real optical researches, disintegration of different branches of the optical science, the demographic situation, some problems with teaching mathematics and physics at schools, and the collision between traditional educational methods and the mentality of the new generation. In Russia the Saint-Petersburg State University of Information Technologies, Mechanics and Optics offers partial solution to these problems: the organization of a real place for interactive optical science in a form of a new museum of optics, intended for education and training, seems to be the most effective way. This was the main reason for establishing such a museum in Saint-Petersburg at the end of 2008.

  16. Direct Observations of Graphene Dispersed in Solution by Twilight Fluorescence Microscopy.

    PubMed

    Matsuno, Yutaka; Sato, Yu-Uya; Sato, Hikaru; Sano, Masahito

    2017-06-01

    Graphene and graphene oxide (GO) in solution were directly observed by a newly developed twilight fluorescence (TwiF) microscopy. A nanocarbon dispersion was mixed with a highly concentrated fluorescent dye solution and placed in a cell with a viewing glass at the bottom. TwiF microscopy images the nanocarbon material floating within a few hundred μm of the glass surface by utilizing two optical processes to provide a faintly illuminating backlight and visualizes GO as either a dark image by absorption and energy transfer processes or a bright image by alternation of fluorophore chemistry and autofluorescence. Individual graphene and GO sheets ranging from submicron to submillimeter widths were clearly imaged at different wavelengths, which were selectable based on the dye used. Graphene could be differentiated from GO coexisting in the same solution. Partial transparency revealed layering and network structures. Motions in tumbling flow were recognized in real time. An effect of changing the solvent and the process of adhesion on the glass surface were followed in situ.

  17. Review of Techniques to Achieve Optical Surface Cleanliness and Their Potential Application to Surgical Endoscopes

    PubMed Central

    Kreeft, Davey; Arkenbout, Ewout Aart; Henselmans, Paulus Wilhelmus Johannes; van Furth, Wouter R.; Breedveld, Paul

    2017-01-01

    A clear visualization of the operative field is of critical importance in endoscopic surgery. During surgery the endoscope lens can get fouled by body fluids (eg, blood), ground substance, rinsing fluid, bone dust, or smoke plumes, resulting in visual impairment. As a result, surgeons spend part of the procedure on intermittent cleaning of the endoscope lens. Current cleaning methods that rely on manual wiping or a lens irrigation system are still far from ideal, leading to longer procedure times, dirtying of the surgical site, and reduced visual acuity, potentially reducing patient safety. With the goal of finding a solution to these issues, a literature review was conducted to identify and categorize existing techniques capable of achieving optically clean surfaces, and to show which techniques can potentially be implemented in surgical practice. The review found that the most promising method for achieving surface cleanliness consists of a hybrid solution, namely, that of a hydrophilic or hydrophobic coating on the endoscope lens and the use of the existing lens irrigation system. PMID:28511635

  18. 77 FR 34427 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

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    ... Clearing''), f/k/a Ridge Clearing and Outsourcing Solutions, Inc. (``Ridge''), as a Member of EDGX, subject... to the Transaction, Apex Clearing's name was Ridge Clearing & Outsourcing Solutions, Inc. Prior to the transaction, Ridge Clearing & Outsourcing Solutions, Inc. contributed its outsourcing operations...

  19. 77 FR 34424 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

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    ... Clearing''), f/k/a Ridge Clearing and Outsourcing Solutions, Inc. (``Ridge''), as a Member of EDGA, subject...'').\\4\\ \\3\\ Prior to the Transaction, Apex Clearing's name was Ridge Clearing & Outsourcing Solutions, Inc. Prior to the transaction, Ridge Clearing & Outsourcing Solutions, Inc. contributed its...

  20. 77 FR 34429 - Self-Regulatory Organizations; C2 Options Exchange, Incorporated: Notice of Filing and Immediate...

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    ... Clearing and Outsourcing Solutions, Inc. (``Apex Clearing'') as a C2 Permit Holder, subject to Apex... Transaction, Apex Clearing's name was Ridge Clearing & Outsourcing Solutions, Inc. Prior to the transaction, Ridge Clearing & Outsourcing Solutions, Inc. contributed its outsourcing operations and all associated...

  1. Label-free DNA biosensor based on a peptide nucleic acid-functionalized microstructured optical fiber-Bragg grating

    NASA Astrophysics Data System (ADS)

    Candiani, Alessandro; Bertucci, Alessandro; Giannetti, Sara; Konstantaki, Maria; Manicardi, Alex; Pissadakis, Stavros; Cucinotta, Annamaria; Corradini, Roberto; Selleri, Stefano

    2013-05-01

    We describe a novel sensing approach based on a functionalized microstructured optical fiber-Bragg grating for specific DNA target sequences detection. The inner surface of a microstructured fiber, where a Bragg grating was previously inscribed, has been functionalized by covalent linking of a peptide nucleic acid probe targeting a DNA sequence bearing a single point mutation implicated in cystic fibrosis (CF) disease. A solution of an oligonucleotide (ON) corresponding to a tract of the CF gene containing the mutated DNA has been infiltrated inside the fiber capillaries and allowed to hybridize to the fiber surface according to the Watson-Crick pairing. In order to achieve signal amplification, ON-functionalized gold nanoparticles were then infiltrated and used in a sandwich-like assay. Experimental measurements show a clear shift of the reflected high order mode of a Bragg grating for a 100 nM DNA solution, and fluorescence measurements have confirmed the successful hybridization. Several experiments have been carried out on the same fiber using the identical concentration, showing the same modulation trend, suggesting the possibility of the reuse of the sensor. Measurements have also been made using a 100 nM mismatched DNA solution, containing a single nucleotide mutation and corresponding to the wild-type gene, and the results demonstrate the high selectivity of the sensor.

  2. Characterizing the localized surface plasmon resonance behaviors of Au nanorings and tracking their diffusion in bio-tissue with optical coherence tomography

    PubMed Central

    Lee, Cheng-Kuang; Tseng, Hung-Yu; Lee, Chia-Yun; Wu, Shou-Yen; Chi, Ting-Ta; Yang, Kai-Min; Chou, Han-Yi Elizabeth; Tsai, Meng-Tsan; Wang, Jyh-Yang; Kiang, Yean-Woei; Chiang, Chun-Pin; Yang, C. C.

    2010-01-01

    The characterization results of the localized surface plasmon resonance (LSPR) of Au nanorings (NRs) with optical coherence tomography (OCT) are first demonstrated. Then, the diffusion behaviors of Au NRs in mouse liver samples tracked with OCT are shown. For such research, aqueous solutions of Au NRs with two different localized surface plasmon resonance (LSPR) wavelengths are prepared and characterized. Their LSPR-induced extinction cross sections at 1310 nm are estimated with OCT scanning of solution droplets on coverslip to show reasonably consistent results with the data at individual LSPR wavelengths and at 1310 nm obtained from transmission measurements of Au NR solutions and numerical simulations. The resonant and non-resonant Au NRs are delivered into mouse liver samples for tracking Au NR diffusion in the samples through continuous OCT scanning for one hour. With resonant Au NRs, the average A-mode scan profiles of OCT scanning at different delay times clearly demonstrate the extension of strong backscattering depth with time. The calculation of speckle variance among successive OCT scanning images, which is related to the local transport speed of Au NRs, leads to the illustrations of downward propagation and spreading of major Au NR motion spot with time. PMID:21258530

  3. An electrooptic probe to determine internal electric fields in a piezoelectric transformer.

    PubMed

    Norgard, Peter; Kovaleski, Scott

    2012-02-01

    A technique using the electrooptic effect to determine the output voltage of an optically clear LiNbO(3) piezoelectric transformer was developed and explored. A brief mathematical description of the solution is provided, as well as experimental data demonstrating a linear response under ac resonant operating conditions. A technique to calibrate the diagnostic was developed and is described. Finally, a sensitivity analysis of the electrooptic response to variations in angular alignment between the LiNbO(3) transformer and the laser probe are discussed.

  4. Whole-body and Whole-Organ Clearing and Imaging Techniques with Single-Cell Resolution: Toward Organism-Level Systems Biology in Mammals.

    PubMed

    Susaki, Etsuo A; Ueda, Hiroki R

    2016-01-21

    Organism-level systems biology aims to identify, analyze, control and design cellular circuits in organisms. Many experimental and computational approaches have been developed over the years to allow us to conduct these studies. Some of the most powerful methods are based on using optical imaging in combination with fluorescent labeling, and for those one of the long-standing stumbling blocks has been tissue opacity. Recently, the solutions to this problem have started to emerge based on whole-body and whole-organ clearing techniques that employ innovative tissue-clearing chemistry. Here, we review these advancements and discuss how combining new clearing techniques with high-performing fluorescent proteins or small molecule tags, rapid volume imaging and efficient image informatics is resulting in comprehensive and quantitative organ-wide, single-cell resolution experimental data. These technologies are starting to yield information on connectivity and dynamics in cellular circuits at unprecedented resolution, and bring us closer to system-level understanding of physiology and diseases of complex mammalian systems. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Optically transparent and durable Al2O3 coatings for harsh environments by ultra short pulsed laser deposition

    NASA Astrophysics Data System (ADS)

    Korhonen, Hannu; Syväluoto, Aki; Leskinen, Jari T. T.; Lappalainen, Reijo

    2018-01-01

    Nowadays, an environmental protection is needed for a number of optical applications in conditions quickly impairing the clarity of optical surfaces. Abrasion resistant optical coatings applied onto plastics are usually based on alumina or polysiloxane technology. In many applications transparent glasses and ceramics need a combination of abrasive and chemically resistant shielding or other protective solutions like coatings. In this study, we intended to test our hypothesis that clear and pore free alumina coating can be uniformly distributed on glass prisms by ultra short pulsed laser deposition (USPLD) technique to protect the sensitive surfaces against abrasives. Abrasive wear tests were carried out by the use of SiC emery paper using specified standard procedures. After the wear tests the measured transparencies of coated prisms turned out to be close those of the prisms before coating. The coating on sensitive surfaces consistently displayed enhanced wear resistance exhibiting still high quality, even after severe wear testing. Furthermore, the coating modified the surface properties towards hydrophobic nature in contrast to untreated prisms, which became very hydrophilic especially due to wear.

  6. Using low-frequency ultrasound to improve the optical clearing of porcine skin

    NASA Astrophysics Data System (ADS)

    Zhong, Huiqing; Guo, Zhouyi; Wei, Huajiang; Zhang, Zude; Zeng, Changchun; Zhai, Juan; He, Yonghong

    2008-12-01

    The glycerol used as an enhancer for tissue optical clearing technique has been researched. However, using it and a physical way of ultrasound enhance optical clearing of tissue reported a few. We researched that the ultrasound whether can improve the optical clearing of dealt with 80% glycerol tissue. The fresh porcine skins divided into four groups. The first group was not dealt with by ultrasound and 80% glycerol, the second group was dealt with by only ultrasound, the third group was dealt with by 80% glycerol and no by ultrasound, and the fourth group was dealt with by both 80% glycerol and ultrasound. And we measured changes in optical scattering of the porcine skins under treatment with OCT. From the OCT images show that the fourth group changed very faster than the other's during the 0~15 min. And it can be clearly seen that there is a significant improvement in the light penetration depth and imaging contrast in a shorter time. It is possible that the low-frequency ultrasound can make disordering of the stratum corneum lipids of the porcine skin (because the cavitation has happened), and improve the speed of 80% glycerol through the stratum corneum of skin. These results proved that using 80% glycerol with the ultrasound can better improve the optical clearing of tissue.

  7. Comparison of seven optical clearing methods for mouse brain

    NASA Astrophysics Data System (ADS)

    Wan, Peng; Zhu, Jingtan; Yu, Tingting; Zhu, Dan

    2018-02-01

    Recently, a variety of tissue optical clearing techniques have been developed to reduce light scattering for imaging deeper and three-dimensional reconstruction of tissue structures. Combined with optical imaging techniques and diverse labeling methods, these clearing methods have significantly promoted the development of neuroscience. However, most of the protocols were proposed aiming for specific tissue type. Though there are some comparison results, the clearing methods covered are limited and the evaluation indices are lack of uniformity, which made it difficult to select a best-fit protocol for clearing in practical applications. Hence, it is necessary to systematically assess and compare these clearing methods. In this work, we evaluated the performance of seven typical clearing methods, including 3DISCO, uDISCO, SeeDB, ScaleS, ClearT2, CUBIC and PACT, on mouse brain samples. First, we compared the clearing capability on both brain slices and whole-brains by observing brain transparency. Further, we evaluated the fluorescence preservation and the increase of imaging depth. The results showed that 3DISCO, uDISCO and PACT posed excellent clearing capability on mouse brains, ScaleS and SeeDB rendered moderate transparency, while ClearT2 was the worst. Among those methods, ScaleS was the best on fluorescence preservation, and PACT achieved the highest increase of imaging depth. This study is expected to provide important reference for users in choosing most suitable brain optical clearing method.

  8. Concept of a Pitot tube able to detect blockage by ice, volcanic ash, sand and insects, and to clear the tube

    NASA Astrophysics Data System (ADS)

    Jackson, David A.

    2015-12-01

    A conceptual coaxial Pitot tube (PT) has been developed using fiber optic sensors combined with actuators to monitor and maintain its correct operation under different environmental conditions. Experiments were performed showing that the dynamic and static tubes can be cleared of ice. It was also demonstrated that the dynamic tube could be cleared of dust and sand which was not the case for the static tube in the coaxial configuration. An approach was proposed to overcome this problem involving a conventional configuration where the static tube was operated independently orthogonal to the dynamic tube, and a second set of sensors and actuators was used. Sensors and associated actuators were developed for temperature and intensity for a linear PT. The aim of this work is to propose a solution for a problem that has caused the loss of the lives of many passengers and crew of aircraft. Resources were not available to test a full implementation of a PT incorporating the proposed modifications.

  9. Structural characterization of casein micelles: shape changes during film formation.

    PubMed

    Gebhardt, R; Vendrely, C; Kulozik, U

    2011-11-09

    The objective of this study was to determine the effect of size-fractionation by centrifugation on the film structure of casein micelles. Fractionated casein micelles in solution were asymmetrically distributed with a small distribution width as measured by dynamic light scattering. Films prepared from the size-fractionated samples showed a smooth surface in optical microscopy images and a homogeneous microstructure in atomic force micrographs. The nano- and microstructure of casein films was probed by micro-beam grazing incidence small angle x-ray scattering (μGISAXS). Compared to the solution measurements, the sizes determined in the film were larger and broadly distributed. The measured GISAXS patterns clearly deviate from those simulated for a sphere and suggest a deformation of the casein micelles in the film. © 2011 IOP Publishing Ltd

  10. Advanced imaging research and development at DARPA

    NASA Astrophysics Data System (ADS)

    Dhar, Nibir K.; Dat, Ravi

    2012-06-01

    Advances in imaging technology have huge impact on our daily lives. Innovations in optics, focal plane arrays (FPA), microelectronics and computation have revolutionized camera design. As a result, new approaches to camera design and low cost manufacturing is now possible. These advances are clearly evident in visible wavelength band due to pixel scaling, improvements in silicon material and CMOS technology. CMOS cameras are available in cell phones and many other consumer products. Advances in infrared imaging technology have been slow due to market volume and many technological barriers in detector materials, optics and fundamental limits imposed by the scaling laws of optics. There is of course much room for improvements in both, visible and infrared imaging technology. This paper highlights various technology development projects at DARPA to advance the imaging technology for both, visible and infrared. Challenges and potentials solutions are highlighted in areas related to wide field-of-view camera design, small pitch pixel, broadband and multiband detectors and focal plane arrays.

  11. 77 FR 34438 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Participants in order to approve Apex Clearing Corporation, f/k/a Ridge Clearing and Outsourcing Solutions, Inc... Clearing & Outsourcing Solutions, Inc. Prior to the transaction, Ridge Clearing & Outsourcing Solutions, Inc. contributed its outsourcing operations and all associated personnel and systems to its affiliated...

  12. Collagen solubility correlates with skin optical clearing.

    PubMed

    Hirshburg, Jason; Choi, Bernard; Nelson, J Stuart; Yeh, Alvin T

    2006-01-01

    Biomedical optics and photomedicine applications are challenged by the turbidity of most biological tissue systems. Nonreactive, biocompatible chemical agents can induce a reversible reduction in optical scattering of collagenous tissues such as human skin. Herein we show that a chemical agent's tissue optical clearing potential is directly related to its collagen solubility, providing a rational design basis for effective, percutaneous formulations.

  13. Optical coherence tomography angiography offers comprehensive evaluation of skin optical clearing in vivo by quantifying optical properties and blood flow imaging simultaneously

    NASA Astrophysics Data System (ADS)

    Guo, Li; Shi, Rui; Zhang, Chao; Zhu, Dan; Ding, Zhihua; Li, Peng

    2016-08-01

    Tissue optical clearing (TOC) is helpful for reducing scattering and enhancing the penetration depth of light, and shows promising potential in optimizing optical imaging performances. A mixture of fructose with PEG-400 and thiazone (FPT) is used as an optical clearing agent in mouse dorsal skin and evaluated with OCT angiography (Angio-OCT) by quantifying optical properties and blood flow imaging simultaneously. It is observed that FPT leads to an improved imaging performance for the deeper tissues. The imaging performance improvement is most likely caused by the FPT-induced dehydration of skin, and the reduction of scattering coefficient (more than ˜40.5%) and refractive-index mismatching (more than ˜25.3%) in the superficial (epidermal, dermal, and hypodermal) layers. A high correlation (up to ˜90%) between the relative changes in refractive-index mismatching and Angio-OCT signal strength is measured. The optical clearing rate is ˜5.83×10-5 cm/s. In addition, Angio-OCT demonstrates enhanced performance in imaging cutaneous hemodynamics with satisfactory spatiotemporal resolution and contrast when combined with TOC, which exhibits a powerful practical application in studying microcirculation.

  14. Effect of annealing temperature on physical properties of solution processed nickel oxide thin films

    NASA Astrophysics Data System (ADS)

    Sahoo, Pooja; Thangavel, R.

    2018-05-01

    In this report, NiO thin films were prepared at different annealing temperatures from nickel acetate precursor by sol-gel spin coating method. These films were characterized by different analytical techniques to obtain their structural, optical morphological and electrical properties using X-ray diffractometer (XRD), Field emission scanning electron microscopy (FESEM), UV-Vis NIR double beam spectrophotometer and Keithley 2450 source meter respectively. FESEM images clearly indicates the formation of a homogenous and porous films. Due to their porosity, they can be used in sensing applications. The optical absorption spectra elucidated that the films are highly transparent and have a suitable band gap which are in similar agreement with earlier reports. The current enhancement under illumination shows the suitability of nanostructured NiO thin films in its application in photovoltaics.

  15. Effect of mixing, concentration and temperature on the formation of mesostructured solutions and their role in the nucleation of DL-valine crystals.

    PubMed

    Jawor-Baczynska, Anna; Moore, Barry D; Sefcik, Jan

    2015-01-01

    We report investigations on the formation of mesostructured solutions in DL-valine-water-2-propanol mixtures, and the crystallization of DL-valine from these solutions. Mesostructured liquid phases, similar to those previously observed in aqueous solutions of glycine and DL-alanine, were observed using Dynamic Light Scattering and Brownian microscopy, in both undersaturated and supersaturated solutions below a certain transition temperature. Careful experimentation was used to demonstrate that the optically clear mesostructured liquid phase, comprising colloidal mesoscale clusters dispersed within bulk solution, is thermodynamically stable and present in equilibrium with the solid phase at saturation conditions. Solutions prepared by slow cooling contained mesoscale clusters with a narrow size distribution and a mean hydrodynamic diameter of around 200 nm. Solutions of identical composition prepared by rapid isothermal mixing of valine aqueous solutions with 2-propanol contained mesoscale clusters which were significantly larger than those observed in slowly cooled solutions. The presence of larger mesoscale clusters was found to correspond to faster nucleation. Observed induction times were strongly dependent on the rapid initial mixing step, although solutions were left undisturbed afterwards and the induction times observed were up to two orders of magnitude longer than the initial mixing period. We propose that mesoscale clusters above a certain critical size are likely to be the location of productive nucleation events.

  16. Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol

    NASA Astrophysics Data System (ADS)

    Yu, Tingting; Qi, Yisong; Wang, Jianru; Feng, Wei; Xu, Jianyi; Zhu, Jingtan; Yao, Yingtao; Gong, Hui; Luo, Qingming; Zhu, Dan

    2016-08-01

    The developed optical clearing methods show great potential for imaging of large-volume tissues, but these methods present some nonnegligible limitations such as complexity of implementation and long incubation times. In this study, we tried to screen out rapid optical clearing agents by means of molecular dynamical simulation and experimental demonstration. According to the optical clearing potential of sugar and sugar-alcohol, we further evaluated the improvement in the optical clearing efficacy of mouse brain samples, imaging depth, fluorescence preservation, and linear deformation. The results showed that drops of sorbitol, sucrose, and fructose could quickly make the mouse brain sample transparent within 1 to 2 min, and induce about threefold enhancement in imaging depth. The former two could evidently enhance the fluorescence intensity of green fluorescent protein (GFP) and prodium iodide (PI) nuclear dye. Fructose could significantly increase the fluorescence intensity of PI, but slightly decrease the fluorescence intensity of GFP. Even though the three agents caused some shrinkage in samples, the contraction in horizontal and longitudinal directions are almost the same.

  17. Optical clearing of melanoma in vivo: characterization by diffuse reflectance spectroscopy and optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Pires, Layla; Demidov, Valentin; Vitkin, I. Alex; Bagnato, Vanderlei; Kurachi, Cristina; Wilson, Brian C.

    2016-08-01

    Melanoma is the most aggressive type of skin cancer, with significant risk of fatality. Due to its pigmentation, light-based imaging and treatment techniques are limited to near the tumor surface, which is inadequate, for example, to evaluate the microvascular density that is associated with prognosis. White-light diffuse reflectance spectroscopy (DRS) and near-infrared optical coherence tomography (OCT) were used to evaluate the effect of a topically applied optical clearing agent (OCA) in melanoma in vivo and to image the microvascular network. DRS was performed using a contact fiber optic probe in the range from 450 to 650 nm. OCT imaging was performed using a swept-source system at 1310 nm. The OCT image data were processed using speckle variance and depth-encoded algorithms. Diffuse reflectance signals decreased with clearing, dropping by ˜90% after 45 min. OCT was able to image the microvasculature in the pigmented melanoma tissue with good spatial resolution up to a depth of ˜300 μm without the use of OCA; improved contrast resolution was achieved with optical clearing to a depth of ˜750 μm in tumor. These findings are relevant to potential clinical applications in melanoma, such as assessing prognosis and treatment responses. Optical clearing may also facilitate the use of light-based treatments such as photodynamic therapy.

  18. Reconfigurable WDM-PON empowered by a low-cost 8-channel directly modulated laser module

    NASA Astrophysics Data System (ADS)

    Zhang, Yi-ming; Liu, Yu; Zhang, Zhi-ke; Zhao, Ze-ping; Tian, Ye; Zhu, Ning-hua

    2017-11-01

    A 10 Gbit/s 16-km-long reconfigurable wavelength-division-multiplexing passive optical network (WDM-PON) is presented empowered by a low-cost multi-channel directly modulated laser (DML) module. Compared with the case using discrete devices in conventional scheme, the proposed DML module provides a cost-effective solution with reduced complexity. The clear eye diagram and the bit error rate ( BER) of less than 2×10-7 with a sensitivity of -7 dBm are obtained. Due to the special packaging design, the crosstalk between channels under condition of simultaneous operation can be negligible.

  19. Automatic and adaptive heterogeneous refractive index compensation for light-sheet microscopy.

    PubMed

    Ryan, Duncan P; Gould, Elizabeth A; Seedorf, Gregory J; Masihzadeh, Omid; Abman, Steven H; Vijayaraghavan, Sukumar; Macklin, Wendy B; Restrepo, Diego; Shepherd, Douglas P

    2017-09-20

    Optical tissue clearing has revolutionized researchers' ability to perform fluorescent measurements of molecules, cells, and structures within intact tissue. One common complication to all optically cleared tissue is a spatially heterogeneous refractive index, leading to light scattering and first-order defocus. We designed C-DSLM (cleared tissue digital scanned light-sheet microscopy) as a low-cost method intended to automatically generate in-focus images of cleared tissue. We demonstrate the flexibility and power of C-DSLM by quantifying fluorescent features in tissue from multiple animal models using refractive index matched and mismatched microscope objectives. This includes a unique measurement of myelin tracks within intact tissue using an endogenous fluorescent reporter where typical clearing approaches render such structures difficult to image. For all measurements, we provide independent verification using standard serial tissue sectioning and quantification methods. Paired with advancements in volumetric image processing, C-DSLM provides a robust methodology to quantify sub-micron features within large tissue sections.Optical clearing of tissue has enabled optical imaging deeper into tissue due to significantly reduced light scattering. Here, Ryan et al. tackle first-order defocus, an artefact of a non-uniform refractive index, extending light-sheet microscopy to partially cleared samples.

  20. Potential application of Chinese traditional medicine (CTM) as enhancer for tissue optical clearing

    NASA Astrophysics Data System (ADS)

    Chen, Wei; Jiang, Jingying; Wang, Ruikang K.; Xu, Kexin

    2009-02-01

    Many biocompatible hyperosmotic agents such as dimethyl sulfoxide(DMSO) have been used as enhancers for tissue optical clearing technique. However, previous investigations showed that DMSO can induce bradycardia, respiratory problems, and alterations in blood pressure. Also, DMSO could potentially alter the chemical structure, and hence the functional properties, of cell membranes. In this talk, Borneol among natural and nontoxic CTMs was introduced as new enhancer for optical clearing of porcine skin tissue since it has been widely used as new penetration promoter in the field of trandermial drug delivery system(TDDS) and been proved to be effective. In the first, the spectral characteristics of borneol was obtained and analyzed by Fourier Transformation Infrared (FTIR) spectrophotometer. And further experimental studies were performed to probe if borneol is capable of optical clearing of porcine skin tissue in vitro with near infrared spectroscopy, double integrating-spheres system and Inverse Adding-Doubling(IAD) algorithm. Spectral results show that light penetration depth into skin tissue got the increase. Meanwhile, absorption coefficient and scattering coefficient of porcine skin treated by borneol got the decrease during the permeation of Borneol. Therefore, Borneol could be potentially used as enhancer for tissue optical clearing to improve non-invasive light-based diagnostic and imaging techniques while practically optical application and clinical safety are under consideration.

  1. Laser Light Scattering with Multiple Scattering Suppression Used to Measure Particle Sizes

    NASA Technical Reports Server (NTRS)

    Meyer, William V.; Tin, Padetha; Lock, James A.; Cannell, David S.; Smart, Anthony E.; Taylor, Thomas W.

    1999-01-01

    Laser light scattering is the technique of choice for noninvasively sizing particles in a fluid. The members of the Advanced Technology Development (ATD) project in laser light scattering at the NASA Lewis Research Center have invented, tested, and recently enhanced a simple and elegant way to extend the concentration range of this standard laboratory particle-sizing technique by several orders of magnitude. With this technique, particles from 3 nm to 3 mm can be measured in a solution. Recently, laser light scattering evolved to successfully size particles in both clear solutions and concentrated milky-white solutions. The enhanced technique uses the property of light that causes it to form tall interference patterns at right angles to the scattering plane (perpendicular to the laser beam) when it is scattered from a narrow laser beam. Such multiple-scattered light forms a broad fuzzy halo around the focused beam, which, in turn, forms short interference patterns. By placing two fiber optics on top of each other and perpendicular to the laser beam (see the drawing), and then cross-correlating the signals they produce, only the tall interference patterns formed by singly scattered light are detected. To restate this, unless the two fiber optics see the same interference pattern, the scattered light is not incorporated into the signal. With this technique, only singly scattered light is seen (multiple-scattered light is rejected) because only singly scattered light has an interference pattern tall enough to span both of the fiber-optic pickups. This technique is simple to use, easy to align, and works at any angle. Placing a vertical slit in front of the signal collection fibers enhanced this approach. The slit serves as an optical mask, and it significantly shortens the time needed to collect good data by selectively masking out much of the unwanted light before cross-correlation is applied.

  2. SLIME: scattering labeled imaging of microvasculature in excised tissues using OCT (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Liu, Yehe; Gu, Shi; Watanabe, Michiko; Rollins, Andrew M.; Jenkins, Michael W.

    2017-02-01

    Abnormal coronary development causes various health problems. However, coronary development remains one of the highly neglected areas in developmental cardiology due to limited technology. Currently, there is not a robust method available to map the microvasculature throughout the entire embryonic heart in 3D. This is a challenging task because it requires both micron level resolution over a large field of view and sufficient imaging depth. Speckle-variance optical coherence tomography (OCT) has reasonable resolution for coronary vessel mapping, but limited penetration depth and sensitivity to bulk motion made it impossible to apply this method to late-stage beating hearts. Some success has been achieved with coronary dye perfusion, but smaller vessels are not efficiently stained and penetration depth is still an issue. To address this problem, we present an OCT imaging procedure using optical clearing and a contrast agent (titanium dioxide) that enables 3D mapping of the coronary microvasculature in developing embryonic hearts. In brief, the hearts of stage 36 quail embryos were perfused with a low viscosity mixture of polyvinyl acetate (PVA) and titanium dioxide through the aorta using micropipette injection. After perfusion, the viscosity of the solution was increased by crosslinking the PVA polymer chains with borate ions. The tissue was then optically cleared. The titanium dioxide particles remaining in the coronaries provided a strong OCT signal, while the rest of the cardiac structures became relatively transparent. Using this technique, we are able to investigate coronary morphologies in different disease models.

  3. In-vitro terahertz spectroscopy of rat skin under the action of dehydrating agents

    NASA Astrophysics Data System (ADS)

    Kolesnikov, Aleksandr S.; Kolesnikova, Ekaterina A.; Tuchina, Daria K.; Terentyuk, Artem G.; Nazarov, Maxim; Skaptsov, Alexander A.; Shkurinov, Alexander P.; Tuchin, Valery V.

    2014-01-01

    In the paper we present the results of study of rat skin and rat subcutaneous tumor under the action of dehydrating agents in terahertz (THz) range (15-30 THz). Frustrated Total Internal Reflection (FTIR) spectra were obtained with infrared Fourier spectrometer Nicolet 6700 and then they were recalculated in the transmittance spectra with Omnic software. Experiments were carried out with healthy and xenografted tumor in skin tissue in vitro. As the dehydrating agents 100% glycerol, 40%-water glucose solution, PEG-600, and propylene glycol were used. To determine the effect of the optical clearing agent (OCA), the alterations of terahertz transmittance for the samples were analyzed. The results have shown that PEG-600 and 40%-glucose water solution are the most effective dehydrating agent. The transmittance of healthy skin after PEG-600 application increased approximately by 6% and the transmittance of tumor tissue after PEG- 600 and 40%-glucose water solution application increased approximately by 8%. Obtained data can be useful for further application of terahertz radiation for tumor diagnostics.

  4. Glass-to-cryogenic-liquid transitions in aqueous solutions suggested by crack healing

    PubMed Central

    Kim, Chae Un; Tate, Mark W.; Gruner, Sol M.

    2015-01-01

    Observation of theorized glass-to-liquid transitions between low-density amorphous (LDA) and high-density amorphous (HDA) water states had been stymied by rapid crystallization below the homogeneous water nucleation temperature (∼235 K at 0.1 MPa). We report optical and X-ray observations suggestive of glass-to-liquid transitions in these states. Crack healing, indicative of liquid, occurs when LDA ice transforms to cubic ice at 160 K, and when HDA ice transforms to the LDA state at temperatures as low as 120 K. X-ray diffraction study of the HDA to LDA transition clearly shows the characteristics of a first-order transition. Study of the glass-to-liquid transitions in nanoconfined aqueous solutions shows them to be independent of the solute concentrations, suggesting that they represent an intrinsic property of water. These findings support theories that LDA and HDA ice are thermodynamically distinct and that they are continuously connected to two different liquid states of water. PMID:26351671

  5. Chemical resistivity of self-assembled monolayer covalently attached to silicon substrate to hydrofluoric acid and ammonium fluoride

    NASA Astrophysics Data System (ADS)

    Saito, N.; Youda, S.; Hayashi, K.; Sugimura, H.; Takai, O.

    2003-06-01

    Self-assembled monolayers (SAMs) were prepared on hydrogen-terminated silicon substrates through chemical vapor deposition using 1-hexadecene (HD) as a precursor. The HD-SAMs prepared in an atmosphere under a reduced pressure (≈50 Pa) showed better chemical resistivities to hydrofluoric acid and ammonium fluoride (NH 4F) solutions than that of an organosilane SAM formed on oxide-covered silicon substrates. The surface covered with the HD-SAM was micro-patterned by vacuum ultraviolet photolithography and consequently divided into two areas terminated with HD-SAM or silicon dioxide. This micro-patterned sample was immersed in a 40 vol.% NH 4F aqueous solution. Surface images obtained by an optical microscopy clearly show that the micro-patterns of HD-SAM/silicon dioxide were successfully transferred into the silicon substrate.

  6. High resolution ultrasound and magnetic resonance imaging of the optic nerve and the optic nerve sheath: anatomic correlation and clinical importance.

    PubMed

    Steinborn, M; Fiegler, J; Kraus, V; Denne, C; Hapfelmeier, A; Wurzinger, L; Hahn, H

    2011-12-01

    We performed a cadaver study to evaluate the accuracy of measurements of the optic nerve and the optic nerve sheath for high resolution US (HRUS) and magnetic resonance imaging (MRI). Five Thiel-fixated cadaver specimens of the optic nerve were examined with HRUS and MRI. Measurements of the optic nerve and the ONSD were performed before and after the filling of the optic nerve sheath with saline solution. Statistical analysis included the calculation of the agreement of measurements and the evaluation of the intraobserver and interobserver variation. Overall a good correlation of measurement values between HRUS and MRI can be found (mean difference: 0.02-0.97 mm). The repeatability coefficient (RC) and concordance correlation coefficient (CCC) values were good to excellent for most acquisitions (RC 0.2-1.11 mm; CCC 0.684-0.949). The highest variation of measurement values was found for transbulbar sonography (RC 0.58-1.83 mm; CCC 0.615/0.608). If decisive anatomic structures are clearly depicted and the measuring points are set correctly, there is a good correlation between HRUS and MRI measurements of the optic nerve and the ONSD even on transbulbar sonography. As most of the standard and cut-off values that have been published for ultrasound are significantly lower than the results obtained with MRI, a reevaluation of sonographic ONSD measurement with correlation to MRI is necessary. © Georg Thieme Verlag KG Stuttgart · New York.

  7. Solid state light engines for bioanalytical instruments and biomedical devices

    NASA Astrophysics Data System (ADS)

    Jaffe, Claudia B.; Jaffe, Steven M.

    2010-02-01

    Lighting subsystems to drive 21st century bioanalysis and biomedical diagnostics face stringent requirements. Industrywide demands for speed, accuracy and portability mean illumination must be intense as well as spectrally pure, switchable, stable, durable and inexpensive. Ideally a common lighting solution could service these needs for numerous research and clinical applications. While this is a noble objective, the current technology of arc lamps, lasers, LEDs and most recently light pipes have intrinsic spectral and angular traits that make a common solution untenable. Clearly a hybrid solution is required to service the varied needs of the life sciences. Any solution begins with a critical understanding of the instrument architecture and specifications for illumination regarding power, illumination area, illumination and emission wavelengths and numerical aperture. Optimizing signal to noise requires careful optimization of these parameters within the additional constraints of instrument footprint and cost. Often the illumination design process is confined to maximizing signal to noise without the ability to adjust any of the above parameters. A hybrid solution leverages the best of the existing lighting technologies. This paper will review the design process for this highly constrained, but typical optical optimization scenario for numerous bioanalytical instruments and biomedical devices.

  8. Viscous optical clearing agent for in vivo optical imaging

    NASA Astrophysics Data System (ADS)

    Deng, Zijian; Jing, Lijia; Wu, Ning; lv, Pengyu; Jiang, Xiaoyun; Ren, Qiushi; Li, Changhui

    2014-07-01

    By allowing more photons to reach deeper tissue, the optical clearing agent (OCA) has gained increasing attention in various optical imaging modalities. However, commonly used OCAs have high fluidity, limiting their applications in in vivo studies with oblique, uneven, or moving surfaces. In this work, we reported an OCA with high viscosity. We measured the properties of this viscous OCA, and tested its successful performances in the imaging of a living animal's skin with two optical imaging modalities: photoacoustic microscopy and optical coherence tomography. Our results demonstrated that the viscous OCA has a great potential in the study of different turbid tissues using various optical imaging modalities.

  9. Monolithically integrated quantum dot optical gain modulator with semiconductor optical amplifier for 10-Gb/s photonic transmission

    NASA Astrophysics Data System (ADS)

    Yamamoto, Naokatsu; Akahane, Kouichi; Umezawa, Toshimasa; Kawanishi, Tetsuya

    2015-03-01

    Short-range interconnection and/or data center networks require high capacity and a large number of channels in order to support numerous connections. Solutions employed to meet these requirements involve the use of alternative wavebands to increase the usable optical frequency range. We recently proposed the use of the T- and O-bands (Thousand band: 1000-1260 nm, Original band: 1260-1360 nm) as alternative wavebands because large optical frequency resources (>60 THz) can be easily employed. In addition, a simple and compact Gb/s-order high-speed optical modulator is a critical photonic device for short-range communications. Therefore, to develop an optical modulator that acts as a highfunctional photonic device, we focused on the use of self-assembled quantum dots (QDs) as a three-dimensional (3D) confined structure because QD structures are highly suitable for realizing broadband optical gain media in the T+O bands. In this study, we use the high-quality broadband QD optical gain to develop a monolithically integrated QD optical gain modulator (QD-OGM) device that has a semiconductor optical amplifier (QD-SOA) for Gb/s-order highspeed optical data generation in the 1.3-μm waveband. The insertion loss of the device can be compensated through the SOA, and we obtained an optical gain change of up to ~7 dB in the OGM section. Further, we successfully demonstrate a 10-Gb/s clear eye opening using the QD-OGM/SOA device with a clock-data recovery sequence at the receiver end. These results suggest that the monolithic QD-EOM/SOA is suitable for increasing the number of wavelength channels for smart short-range communications.

  10. Optical Dating of Holocene Dune Sands in the Ferris Dune Field, Wyoming

    NASA Astrophysics Data System (ADS)

    Stokes, Stephen; Gaylord, David R.

    1993-05-01

    Optical dating of late Quaternary quartz dune sands from the Clear Creek portion of Ferris dune field, Wyoming, demonstrates the considerable potential of the technique as a chronostratigraphic tool. A sequence of radiocarbon-dated Holocene interdune strata permit optical dating of the intercalated dune sand to be tested; the concordance is good. The optical dates for the aeolian deposits not datable by radiocarbon suggest that aeolian sedimentation at Clear Creek peaked during two relatively short phases at ca. 8500 and 4000 yr B.P. The dates indicate that aeolian accumulation maxima (at least in the Clear Creek area) may not be synchronous with previously defined phases of marked aridity.

  11. Controlling morphology and chain aggregation in semiconducting conjugated polymers: the role of solvent on optical gain in MEH-PPV.

    PubMed

    Lampert, Zach E; Reynolds, C Lewis; Papanikolas, John M; Aboelfotoh, M Osama

    2012-10-25

    We report the results of a detailed investigation that addresses the influence of polymer morphology and chain aggregation, as controlled by the chemical nature of the solvent, on the optical gain properties of the conjugated polymer poly[2-methoxy-5-(2'-ethylhexyloxy)-p-phenylene vinylene] (MEH-PPV). Using the variable stripe length technique in the picosecond regime, we have extensively studied the optical gain performance of asymmetric planar waveguides formed with thin MEH-PPV films spin-cast from concentrated chlorobenzene (CB) and tetrahydrofuran (THF) solutions onto thermally oxidized silicon substrates. CB and THF solvents were chosen based on their known ability to promote and effectively limit aggregate formation, respectively. Very large net gain coefficients are demonstrated, reaching values of 330 and 365 cm(-1), respectively, when optically pumping the waveguides with a maximum energy density of 85 μJ/cm(2). Our results clearly demonstrate that polymer morphology, and hence, the chain conformation dependence of the degree of aggregation in the films as controlled by the solvent, has minimal impact on the net gain. Moreover, the waveguides exhibit low loss coefficients of 10-20 cm(-1) at the ASE wavelength. These results question the importance of polymer morphology and aggregate formation in polymer-based optical devices operating at high excitation densities in the stimulated emission regime as would be characteristic of lasers and optical amplifiers.

  12. Absorptive carbon nanotube electrodes: Consequences of optical interference loss in thin film solar cells

    NASA Astrophysics Data System (ADS)

    Tait, Jeffrey G.; de Volder, Michaël F. L.; Cheyns, David; Heremans, Paul; Rand, Barry P.

    2015-04-01

    A current bottleneck in the thin film photovoltaic field is the fabrication of low cost electrodes. We demonstrate ultrasonically spray coated multiwalled carbon nanotube (CNT) layers as opaque and absorptive metal-free electrodes deposited at low temperatures and free of post-deposition treatment. The electrodes show sheet resistance as low as 3.4 Ω □-1, comparable to evaporated metallic contacts deposited in vacuum. Organic photovoltaic devices were optically simulated, showing comparable photocurrent generation between reflective metal and absorptive CNT electrodes for photoactive layer thickness larger than 600 nm when using archetypal poly(3-hexylthiophene) (P3HT) : (6,6)-phenyl C61-butyric acid methyl ester (PCBM) cells. Fabricated devices clearly show that the absorptive CNT electrodes display comparable performance to solution processed and spray coated Ag nanoparticle devices. Additionally, other candidate absorber materials for thin film photovoltaics were simulated with absorptive contacts, elucidating device design in the absence of optical interference and reflection.A current bottleneck in the thin film photovoltaic field is the fabrication of low cost electrodes. We demonstrate ultrasonically spray coated multiwalled carbon nanotube (CNT) layers as opaque and absorptive metal-free electrodes deposited at low temperatures and free of post-deposition treatment. The electrodes show sheet resistance as low as 3.4 Ω □-1, comparable to evaporated metallic contacts deposited in vacuum. Organic photovoltaic devices were optically simulated, showing comparable photocurrent generation between reflective metal and absorptive CNT electrodes for photoactive layer thickness larger than 600 nm when using archetypal poly(3-hexylthiophene) (P3HT) : (6,6)-phenyl C61-butyric acid methyl ester (PCBM) cells. Fabricated devices clearly show that the absorptive CNT electrodes display comparable performance to solution processed and spray coated Ag nanoparticle devices. Additionally, other candidate absorber materials for thin film photovoltaics were simulated with absorptive contacts, elucidating device design in the absence of optical interference and reflection. Electronic supplementary information (ESI) available: An animation of the MWCNT spray coating process, and five figures, including: a photograph of completed devices with MWCNT electrodes, performance metrics for devices with photoactive layer thickness up to 3000 nm, contour plots of simulated devices used to build Fig. 5, simulation data for perovskite devices, and a contour plot of the simplified equation of photoactive layer thickness required to attain a specified photocurrent ratio (x-axis) and absorption coefficient (y-axis). See DOI: 10.1039/c5nr01119a

  13. Optical Eigenvector.

    DTIC Science & Technology

    1984-10-01

    it necessary and identify by blckci -. mbrr, ’At tile bneginninp, of this contract , bot], -,-j- .lc the rest of the optical community imagined * that...simple analog optical computer,, could produce satisfactory solutions to elgenproblems. Earl’ - in this contract we improved optical computing... contract both we and the rest of the optical community imagined that simple analog optical computers could produce . satisfactory solutions to

  14. Optical limiting device and method of preparation thereof

    DOEpatents

    Wang, Hsing-Lin; Xu, Su; McBranch, Duncan W.

    2003-01-01

    Optical limiting device and method of preparation thereof. The optical limiting device includes a transparent substrate and at least one homogeneous layer of an RSA material in polyvinylbutyral attached to the substrate. The device may be produced by preparing a solution of an RSA material, preferably a metallophthalocyanine complex, and a solution of polyvinylbutyral, and then mixing the two solutions together to remove air bubbles. The resulting solution is layered onto the substrate and the solvent is evaporated. The method can be used to produce a dual tandem optical limiting device.

  15. Photoacoustic detection of blood in dental pulp by using short-time Fourier transform

    NASA Astrophysics Data System (ADS)

    Yamada, Azusa; Kakino, Satoko; Matsuura, Yuji

    2016-03-01

    A method based on photoacoustic analysis is proposed to diagnose dental pulp vitality. Photoacoustic analysis enables to get signal from deeper tissues than other optical analyses and therefore, signal detection from root canal of thick dental tissues such as molar teeth is expected. As a light source for excitation of photoacoustic waves, a microchip Q-switched YAG laser with a wavelength of 1064 nm was used and owing to large penetration depth of the near infrared laser, photoacoustic signals from dental root were successfully obtained. It was found that the photoacoustic signals from the teeth containing hemoglobin solution in the pulp cavity provide vibration in high frequency region. It was also shown that the intensities of the high frequency component have correlation with the hemoglobin concentration of solution. We applied short-time Fourier transform for evaluation of photoacoustic signals and this analysis clearly showed photoacoustic signals from dental root.

  16. Laser light propagation in adipose tissue and laser effects on adipose cell membranes

    NASA Astrophysics Data System (ADS)

    Solarte, Efraín; Rebolledo, Aldo; Gutierrez, Oscar; Criollo, William; Neira, Rodrigo; Arroyave, José; Ramírez, Hugo

    2006-01-01

    Recently Neira et al. have presented a new liposuction technique that demonstrated the movement of fat from inside to outside of the cell, using a low-level laser device during a liposuction procedure with Ultrawet solution. The clinical observations, allowed this new surgical development, started a set of physical, histological and pharmacological studies aimed to determine the mechanisms involved in the observed fat mobilization concomitant to external laser application in liposuction procedures. Scanning and Transmission Electron Microscopy, studies show that the cellular arrangement of normal adipose tissue changes when laser light from a diode laser: 10 mW, 635 nm is applied. Laser exposures longer than 6 minutes cause the total destruction of the adipocyte panicles. Detailed observation of the adipose cells show that by short irradiation times (less than four minutes) the cell membrane exhibits dark zones, that collapse by longer laser exposures. Optical measurements show that effective penetration length depends on the laser intensity. Moreover, the light scattering is enhanced by diffraction and subsequent interference effects, and the tumescent solution produces a clearing of the tissue optical medium. Finally, isolate adipose cell observation show that fat release from adipocytes is a concomitant effect between the tumescent solution (adrenaline) and laser light, revealing a synergism which conduces to the aperture, and maybe the disruption, of the cell membrane. All these studies were consistent with a laser induced cellular process, which causes fat release from inside the adipocytes into the intercellular space, besides a strong modification of the cellular membranes.

  17. Optical coherence tomography of the effects of stromal hydration on clear corneal incision architecture.

    PubMed

    Calladine, Daniel; Tanner, Vaughan

    2009-08-01

    To evaluate the effects of stromal hydration on clear corneal incision (CCI) architecture immediately after surgery using anterior segment optical coherence tomography (AS-OCT). Department of Ophthalmology, Royal Berkshire Hospital, Reading, United Kingdom. Clear corneal incisions in adult eyes were examined using a Visante AS-OCT imaging system within 1 hour of surgery. Half the CCIs had stromal hydration with a balanced salt solution and half did not. Incisions were made with a 2.75 mm steel keratome. Intraocular pressure (IOP) was measured within 90 minutes after surgery. The CCI length and corneal thickness at the CCI site were measured using software built into the AS-OCT system. Thirty CCIs were evaluated. Stromal hydration significantly increased the measured CCI length (P<.05, t test); this was the result of a trend toward increased corneal thickness at the CCI site with hydration (P<.1, t test). The mean CCI length was 1.69 mm +/- 0.27 (SD) (range 1.31 to 2.32 mm) with hydration and 1.51 +/- 0.23 mm (range 1.30 to 1.95 mm) without hydration. The mean IOP was 20.9 +/- 8.18 mm Hg and 15.8 +/- 8.20 mm Hg, respectively. The IOP tended to be higher with hydration (P<.1, t test). Local detachment of Descemet membrane was more likely with stromal hydration (63%) than without (25%). Stromal hydration significantly increased CCI length and tended to leave the eye with a higher early postoperative IOP, showing the importance of taking stromal hydration into account when designing similar OCT studies of CCI architecture.

  18. X-ray study of mesomorphism of bent-core and chromonic mesogens

    NASA Astrophysics Data System (ADS)

    Joshi, Leela Pradhan

    The discovery of thermotropic biaxial nematic phase in bent-core mesogens, have engendered interest in these systems. Also, it undergoes optical switching about 100 times faster than conventional uniaxial nematic liquid crystal. Azo-substituted bent-core compounds, A131 and A103, were investigated as both offer an opportunity to observe their structures and phase transitions from the uniaxial nematic (Nu) to biaxial nematic (Nb) phase and from Nb to the underlying smectic-C (SmC) phase. Plank-like molecular systems are also expected to form Nb phase. Chromonic liquid crystals formed by aqueous solutions of plank-like dye molecules are interesting for their unique self-assembly and structural evolution. They have applications in optical element, coloring in food and textiles, and etc. Both systems were investigated with synchrotron x-ray scattering, polarizing optical microscopy, and differential scanning calorimetry. Temperature dependence of d-spacing and positional order correlations along the director clearly mark the phase boundaries where Nu-Nb transition was approximately 27° below the clearing point. Positional order correlation length of A131 increased from 1.5 in Nu to 3.3 molecular lengths in Nb phase, before it jumps by a factor of at least 5 in SmC phase. The lack of large discontinuous changes in the structural parameters and the subtle signatures in heat capacity establish the second order nature of Nu-Nb and Nb-SmC phase transitions. The chromonic system investigation results provide quantitative information of structural properties in nematic and columnar mesophases. We studied water solutions of (achiral) sunset yellow dye and (chiral and achiral) dihydrochloride salts of perylenebis-dicarboxydiimide. Positional order correlation lengths measurements, parallel and perpendicular to the aggregate axis, revealed that they increase with concentration and decrease with temperature. Temperature dependence of correlation lengths yielded the scission energy to be 1.8 (+/-0.1) x10-20J and 1.5 (+/-0.08) x10-20J in the nematic and columnar phases. The aggregates' small aspect ratio (2.5) is inconsistent with the Onsager model for the formation of an orientationally ordered phase, which strongly suggests more complicated aggregate-shape than simple cylindrical objects as postulated by Laventovich, et al.

  19. Pupil size stability of the cubic phase mask solution for presbyopia

    NASA Astrophysics Data System (ADS)

    Almaguer, Citlalli; Acosta, Eva; Arines, Justo

    2018-01-01

    Presbyopia correction involves different types of studies such as lens design, clinical study, and the development of objective metrics, such as the visual Strehl ratio. Different contact lens designs have been proposed for presbyopia correction, but performance depends on pupil diameter. We will analyze the potential use of a nonsymmetrical element, a cubic phase mask (CPM) solution, to develop a contact or intraocular lens whose performance is nearly insensitive to changes in pupil diameter. We will show the through focus optical transfer function of the proposed element for different pupil diameters ranging from 3 to 7 mm. Additionally, we will show the images obtained through computation and experiment for a group of eye charts with different visual acuities. Our results show that a CPM shaped as 7.07 μm*(Z33-Z3-3)-0.9 μm Z20 is a good solution for a range of clear vision with a visual acuity of at least 0.1 logMar from 0.4 to 6 m for pupil diameters in the 3- to 7-mm range. Our results appear to be a good starting point for further development and study of this kind of CPM solution for presbyopia.

  20. Oil-in-water emulsion impregnated electrospun poly(ethylene terephthalate) fiber mat as a novel tool for optical fiber cleaning.

    PubMed

    Devlaminck, Dries J G; Rahman, Md Mahbubor; Dash, Mamoni; Samal, Sangram Keshari; Watté, Jan; Van Vlierberghe, Sandra; Dubruel, Peter

    2018-06-15

    The complete removal of remaining polymer debris after stripping of optical fiber cables is essential for high precision connection between two fibers. It can be anticipated that electrospun porous membranes as cleaning wipes are able to trap and retain polymer debris within their pores. Impregnation of an oil-in-water emulsion as cleaning agent lowers the interfacial tension between debris and the optical fiber thereby enabling the straightforward removal of polymer debris from the optical fiber. Electrospun membranes of poly(ethylene terephthalate) (PET) and cellulose acetate (CA) were obtained with fiber diameters of 0.430 μm and 2 μm respectively. The oil-in-water emulsion was formulated with 10 wt% medium chain triglyceride (MCT) and 10 wt% Tween 80 surfactant in an aqueous phosphate buffer solution. In a scoring range from 0 to 5 for which the score 0 indicated superior cleaning and the score 5 referred to the least efficient cleaning, the electrospun fiber mats (without emulsion) scored within the range of 2-4 while emulsion impregnated electrospun fiber mats revealed the best score of 0. A drastic improvement was thus clearly evident from the obtained results when the cleaning emulsion was applied. The materials developed herein thus represent a new class of soft cleaning agents for optical fibers. Copyright © 2018 Elsevier Inc. All rights reserved.

  1. Influence of acid and alkaline sources on optical, structural and photovoltaic properties of CdSe nanoparticles precipitated from aqueous solution

    NASA Astrophysics Data System (ADS)

    Coria-Monroy, C. Selene; Sotelo-Lerma, Mérida; Hu, Hailin

    2016-06-01

    CdSe is a widely researched material for photovoltaic applications. One of the most important parameters of the synthesis is the pH value, since it determines the kinetics and the mechanism of the reaction and in consequence, the optical and morphological properties of the products. We present the synthesis of CdSe in solution with strict control of pH and the comparison of ammonia and KOH as alkaline sources and diluted HCl as acid medium. CdSe formation was monitored with photoluminescence emission spectra (main peak in 490 nm, bandgap of CdSe nanoparticles). XRD patterns indicated that CdSe nanoparticles are mainly of cubic structure for ammonia and HCl, but the hexagonal planes appear with KOH. Product yield decreases with pH and also decreases with KOH at constant pH value since ammonia has a double function, as complexing agent and alkaline source. Changes in morphology were observed in SEM images as well with the different alkaline source. The effect of alkaline sources on photovoltaic performance of hybrid organic solar cells with CdSe and poly(3-hexylthiophene) as active layers was clearly observed, indicating the importance of synthesis conditions on optoelectronic properties of promising semiconductor nanomaterials for solar cell applications.

  2. Optical pulse characteristics of sonoluminescence at low acoustic drive levels.

    PubMed

    Arakeri, V H; Giri, A

    2001-06-01

    From a nonaqueous alkali-metal salt solution, it is possible to observe sonoluminescence (SL) at low acoustic drive levels with the ratio of the acoustic pressure amplitude to the ambient pressure being about 1. In this case, the emission has a narrowband spectral content and consists of a few flashes of light from a levitated gas bubble going through an unstable motion. A systematic statistical study of the optical pulse characteristics of this form of SL is reported here. The results support our earlier findings [Phys. Rev. E 58, R2713 (1998)], but in addition we have clearly established a variation in the optical pulse duration with certain physical parameters such as the gas thermal conductivity. Quantitatively, the SL optical pulse width is observed to vary from 10 ns to 165 ns with the most probable value being 82 ns, for experiments with krypton-saturated sodium salt ethylene glycol solution. With argon, the variation is similar to that of krypton but the most probable value is reduced to 62 ns. The range is significantly smaller with helium, being from 22 ns to 65 ns with the most probable value also being reduced to 42 ns. The observed large variation, for example with krypton, under otherwise fixed controllable experimental parameters indicates that it is an inherent property of the observed SL process, which is transient in nature. It is this feature that necessitated our statistical study. Numerical simulations of the SL process using the bubble dynamics approach of Kamath, Prosperetti, and Egolfopoulos [J. Acoust. Soc. Am. 94, 248 (1993)] suggest that a key uncontrolled parameter, namely the initial bubble radius, may be responsible for the observations. In spite of the fact that certain parameters in the numerical computations have to be fixed from a best fit to one set of experimental data, the observed overall experimental trends of optical pulse characteristics are predicted reasonably well.

  3. Optical pulse characteristics of sonoluminescence at low acoustic drive levels

    NASA Astrophysics Data System (ADS)

    Arakeri, Vijay H.; Giri, Asis

    2001-06-01

    From a nonaqueous alkali-metal salt solution, it is possible to observe sonoluminescence (SL) at low acoustic drive levels with the ratio of the acoustic pressure amplitude to the ambient pressure being about 1. In this case, the emission has a narrowband spectral content and consists of a few flashes of light from a levitated gas bubble going through an unstable motion. A systematic statistical study of the optical pulse characteristics of this form of SL is reported here. The results support our earlier findings [Phys. Rev. E 58, R2713 (1998)], but in addition we have clearly established a variation in the optical pulse duration with certain physical parameters such as the gas thermal conductivity. Quantitatively, the SL optical pulse width is observed to vary from 10 ns to 165 ns with the most probable value being 82 ns, for experiments with krypton-saturated sodium salt ethylene glycol solution. With argon, the variation is similar to that of krypton but the most probable value is reduced to 62 ns. The range is significantly smaller with helium, being from 22 ns to 65 ns with the most probable value also being reduced to 42 ns. The observed large variation, for example with krypton, under otherwise fixed controllable experimental parameters indicates that it is an inherent property of the observed SL process, which is transient in nature. It is this feature that necessitated our statistical study. Numerical simulations of the SL process using the bubble dynamics approach of Kamath, Prosperetti, and Egolfopoulos [J. Acoust. Soc. Am. 94, 248 (1993)] suggest that a key uncontrolled parameter, namely the initial bubble radius, may be responsible for the observations. In spite of the fact that certain parameters in the numerical computations have to be fixed from a best fit to one set of experimental data, the observed overall experimental trends of optical pulse characteristics are predicted reasonably well.

  4. Eikonal solutions to optical model coupled-channel equations

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis A.; Khandelwal, Govind S.; Maung, Khin M.; Townsend, Lawrence W.; Wilson, John W.

    1988-01-01

    Methods of solution are presented for the Eikonal form of the nucleus-nucleus coupled-channel scattering amplitudes. Analytic solutions are obtained for the second-order optical potential for elastic scattering. A numerical comparison is made between the first and second order optical model solutions for elastic and inelastic scattering of H-1 and He-4 on C-12. The effects of bound-state excitations on total and reaction cross sections are also estimated.

  5. 77 FR 34422 - Self-Regulatory Organizations; Chicago Stock Exchange, Incorporated; Notice of Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Clearing and Outsourcing Solutions, Inc. (``Apex Clearing''), as a CHX Participant and TPH. The text of... as it pertains to the application approval process of a CHX Participant \\5\\ and TPH \\6\\ in order to...'').\\9\\ \\8\\ Prior to the Transaction, Apex Clearing's name was Ridge Clearing & Outsourcing Solutions...

  6. Motion compensation for in vivo subcellular optical microscopy.

    PubMed

    Lucotte, B; Balaban, R S

    2014-04-01

    In this review, we focus on the impact of tissue motion on attempting to conduct subcellular resolution optical microscopy, in vivo. Our position is that tissue motion is one of the major barriers in conducting these studies along with light induced damage, optical probe loading as well as absorbing and scattering effects on the excitation point spread function and collection of emitted light. Recent developments in the speed of image acquisition have reached the limit, in most cases, where the signal from a subcellular voxel limits the speed and not the scanning rate of the microscope. Different schemes for compensating for tissue displacements due to rigid body and deformation are presented from tissue restriction, gating, adaptive gating and active tissue tracking. We argue that methods that minimally impact the natural physiological motion of the tissue are desirable because the major reason to perform in vivo studies is to evaluate normal physiological functions. Towards this goal, active tracking using the optical imaging data itself to monitor tissue displacement and either prospectively or retrospectively correct for the motion without affecting physiological processes is desirable. Critical for this development was the implementation of near real time image processing in conjunction with the control of the microscope imaging parameters. Clearly, the continuing development of methods of motion compensation as well as significant technological solutions to the other barriers to tissue subcellular optical imaging in vivo, including optical aberrations and overall signal-to-noise ratio, will make major contributions to the understanding of cell biology within the body.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bourlier, Yoan; Cristini Robbe, Odile; Laboratoire de Physique des Lasers, Atomes et Molécules

    Highlights: • CuIn{sub (1−x)}Ga{sub x}S{sub 2} thin films were prepared by sol–gel process. • Evolution of lattice parameters is characteristic of a solid solution. • Optical band gap was found to be linearly dependent on the gallium rate. - Abstract: In this paper, we report the elaboration of Cu(In,Ga)S{sub 2} chalcopyrite thin films via a sol–gel process. To reach this aim, solutions containing copper, indium and gallium complexes were prepared. These solutions were thereafter spin-coated onto the soda lime glass substrates and calcined, leading to metallic oxides thin films. Expected chalcopyrite films were finally obtained by sulfurization of oxides layersmore » using a sulfur atmosphere at 500 °C. The rate of gallium incorporation was studied both at the solutions synthesis step and at the thin films sulfurization process. Elemental and X-ray diffraction (XRD) analyses have shown the efficiency of monoethanolamine used as a complexing agent for the preparation of CuIn{sub (1−x)}Ga{sub x}S{sub 2} thin layers. Moreover, the replacement of diethanolamine by monoethanolamine has permitted the substitution of indium by isovalent gallium from x = 0 to x = 0.4 and prevented the precipitation of copper derivatives. XRD analyses of sulfurized thin films CuIn{sub (1−x)}Ga{sub x}S{sub 2,} clearly indicated that the increasing rate of gallium induced a shift of XRD peaks, revealing an evolution of the lattice parameter in the chalcopyrite structure. These results were confirmed by Raman analyses. Moreover, the optical band gap was also found to be linearly dependent upon the gallium rate incorporated within the thin films: it varies from 1.47 eV for x = 0 to 1.63 eV for x = 0.4.« less

  8. Black synthetic quartz glass layer for optical fiber cross-talk reduction fabricated by VAD method

    NASA Astrophysics Data System (ADS)

    Kobayashi, Soichi; Fukuda, Kaoru; Onishi, Gen; Fujii, Yusuke

    2016-09-01

    In this report the new black-glass fiber-preform fabricated by the vapor-phase axial deposition (VAD) method to realize high-resolution optical bundle fibers is discussed with the Energy Dispersive X-ray (EDX) analysis and the transmittance spectrum measurement. The black glass consists of SiO2, GeO2, Bi2O3 and Al2O3. Firstly, the rod-shaped soot of SiO2 and GeO2 is prepared by blowing SiCl4 and GeCl4 into the oxyhydrogen burner. Then the soot is dipped into the solution of the Bi and Al compounds. After drying the soot with Bi and Al penetrated, the soot is consolidated into the glass preform by heating with the carbon heater at 1650 degrees Celsius. The diameter of the obtained preform is 10.5 mm and the black glass layer thickness is 2.6 mm located at the periphery. The Bi concentration distribution shows the content of several wt% in the black glass layer. The black glass preform is drawn into the black optical fiber being expected to make a clear image because of no light leaking from the neighboring optical fibers as compared to the conventional fiber endoscope.

  9. Collaborative effects of wavefront shaping and optical clearing agent in optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Yu, Hyeonseung; Lee, Peter; Jo, YoungJu; Lee, KyeoReh; Tuchin, Valery V.; Jeong, Yong; Park, YongKeun

    2016-12-01

    We demonstrate that simultaneous application of optical clearing agents (OCAs) and complex wavefront shaping in optical coherence tomography (OCT) can provide significant enhancement of penetration depth and imaging quality. OCA reduces optical inhomogeneity of a highly scattering sample, and the wavefront shaping of illumination light controls multiple scattering, resulting in an enhancement of the penetration depth and signal-to-noise ratio. A tissue phantom study shows that concurrent applications of OCA and wavefront shaping successfully operate in OCT imaging. The penetration depth enhancement is further demonstrated for ex vivo mouse ears, revealing hidden structures inaccessible with conventional OCT imaging.

  10. Optimized optical clearing method for imaging central nervous system

    NASA Astrophysics Data System (ADS)

    Yu, Tingting; Qi, Yisong; Gong, Hui; Luo, Qingming; Zhu, Dan

    2015-03-01

    The development of various optical clearing methods provides a great potential for imaging entire central nervous system by combining with multiple-labelling and microscopic imaging techniques. These methods had made certain clearing contributions with respective weaknesses, including tissue deformation, fluorescence quenching, execution complexity and antibody penetration limitation that makes immunostaining of tissue blocks difficult. The passive clarity technique (PACT) bypasses those problems and clears the samples with simple implementation, excellent transparency with fine fluorescence retention, but the passive tissue clearing method needs too long time. In this study, we not only accelerate the clearing speed of brain blocks but also preserve GFP fluorescence well by screening an optimal clearing temperature. The selection of proper temperature will make PACT more applicable, which evidently broaden the application range of this method.

  11. A Hybrid Solution for Simultaneous Transfer of Ultrastable Optical Frequency, RF Frequency, and UTC Time-Tags Over Optical Fiber.

    PubMed

    Krehlik, Przemyslaw; Schnatz, Harald; Sliwczynski, Lukasz

    2017-12-01

    We describe a fiber-optic solution for simultaneous distribution of all signals generated at today's most advanced time and frequency laboratories, i.e., an ultrastable optical reference frequency derived from an optical atomic clock, a radio frequency precisely linked to a realization of the SI-Second, and a realization of an atomic timescale, being the local representation of the virtual, global UTC timescale. In our solution both the phase of the optical carrier and the delay of electrical signals (10-MHz frequency reference and one-pulse-per-second time tags) are stabilized against environmental perturbations influencing the fiber link instability and accuracy. We experimentally demonstrate optical transfer stabilities of and for 100 s averaging period, for optical carrier and 10-MHz signals, respectively.

  12. Importance of molecular Rayleigh scattering in the enhancement of clear sky reflectance in the vicinity of boundary layer cumulus clouds

    NASA Astrophysics Data System (ADS)

    Wen, Guoyong; Marshak, Alexander; Cahalan, Robert F.

    2008-12-01

    Clouds increase the complexity of atmospheric radiative transfer processes, particularly for aerosol retrievals in clear regions in the vicinity of clouds. This study focuses on identifying mechanisms responsible for the enhancement of nadir reflectance in clear regions in the vicinity of cumulus clouds and quantifies the relative importance of each mechanism. Using cloud optical properties and surface albedo derived from Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) and Moderate Resolution Imaging Spectroradiometer (MODIS), we performed extensive Monte Carlo simulations of radiative transfer in two cumulus scenes in a biomass burning region in Brazil. The results show that the scattering of radiation by clouds, followed by upward Rayleigh scattering by molecules above cloud top over clear gaps, is the dominant mechanism for the enhancement of visible reflectance in clear regions in boundary layer cumulus field over dark surfaces with aerosols trapped in the boundary layer. The Rayleigh scattering contributes ˜80% and ˜50% to the total enhancement for wavelengths 0.47 μm (with aerosol optical thickness 0.2) and 0.66 μm (with aerosol optical thickness 0.1), respectively. Out of the total contribution of molecular scattering, ˜90% arises from the clear atmosphere above cloud top height. The mechanism is valid for a large range of aerosol optical thicknesses (up to 1 in this study) for 0.47 μm, and for aerosol optical thickness up to 0.2 for 0.66 μm. Our results provide a basis to develop simplifications for future aerosol remote sensing from satellite.

  13. Effect of Pre-Annealing on Thermal and Optical Properties of ZnO and Al-ZnO Thin Films

    NASA Astrophysics Data System (ADS)

    Saravanan, P.; Gnanavelbabu, A.; Pandiaraj, P.

    Zinc oxide (ZnO) nanoparticles were synthesized by a simple solution route method using zinc acetate as the precursor and ethanol as the solvent. At a temperature of 60∘C, a clear homogenous solution is heated to 100∘C for ethanol evaporation. Then the obtained precursor powder is annealed at 600∘C for the formation of ZnO nanocrystalline structure. Doped ZnO particle is also prepared by using aluminum nitrate nonahydrate to produce aluminum (Al)-doped nanoparticles using the same solution route method followed by annealing. Thin film fabrication is done by air evaporation method using the polymer polyvinyl alcohol (PVA). To analyze the optical and thermal properties for undoped and doped ZnO nanocrystalline thin film by precursor annealing, characterizations such as UV, FTIR, AFM, TGA/DTA, XRD, EDAX and Photoluminescence (PL) were also taken. It was evident that precursor annealing had great influence on thermal and optical properties of thin films while ZnO and AZO film showed low crystallinity and intensity than in the powder form. TGA/DTA suggests pre-annealing effect improves the thermal stability, which ensures that Al ZnO nanoparticle can withstand at high temperature too which is the crucial advantage in the semiconductor devices. UV spectroscopy confirmed the presence of ZnO nanoparticles in the thin film by an absorbance peak observed at 359nm with an energy bandgap of 3.4eV. A peak obtained at 301nm with an energy bandgap of 4.12eV shows a blue shift due to the presence of Al-doped ZnO nanoparticles. Both ZnO and AZO bandgap increased due to precursor annealing. In this research, PL spectrum is also studied in order to determine the optical property of the nanoparticle embedded thin film. From PL spectrum, it is observed that the intensity of the doped ZnO is much more enhanced as the dopant concentration is increased to 1wt.% and 2wt.% of Al in ZnO.

  14. Optical solitons, explicit solutions and modulation instability analysis with second-order spatio-temporal dispersion

    NASA Astrophysics Data System (ADS)

    Inc, Mustafa; Isa Aliyu, Aliyu; Yusuf, Abdullahi; Baleanu, Dumitru

    2017-12-01

    This paper obtains the dark, bright, dark-bright or combined optical and singular solitons to the nonlinear Schrödinger equation (NLSE) with group velocity dispersion coefficient and second-order spatio-temporal dispersion coefficient, which arises in photonics and waveguide optics and in optical fibers. The integration algorithm is the sine-Gordon equation method (SGEM). Furthermore, the explicit solutions of the equation are derived by considering the power series solutions (PSS) theory and the convergence of the solutions is guaranteed. Lastly, the modulation instability analysis (MI) is studied based on the standard linear-stability analysis and the MI gain spectrum is obtained.

  15. Determination of optimal glycerol concentration for optical tissue clearing

    NASA Astrophysics Data System (ADS)

    Youn, Eungjun; Son, Taeyoon; Kim, Han-Sung; Jung, Byungjo

    2012-02-01

    The laser scattering in tissue is significant in diagnostic and therapeutic purposes of laser. Many studies have been conducted to minimize laser scattering in tissue and therefore, to maximize the clinical efficacy by enhancing photon density. Optical clearing agents (OCAs) have been employed for optical tissue clearing (OTC). This study was aimed to investigate the optimal concentration of an OCA, glycerol, in topical application,, so that it can be utilized for clinical diagnosis and therapy in dermatology. Glycerol was topically applied to avoid possible edema caused by dermal injection. The effect of OTC was quantitatively evaluated as a function of the concentration of glycerol with various methods. Optical methods such as optical coherence tomography (OCT) and an integrating sphere were used to assess the enhancement of light penetration depth and refractive index matching. In addition, a non-optical method, ultrasound scanner, was utilized to evaluate quantitatively collagen dissociation. The results revealed that 70 % glycerol was the optimal concentration of OTC for topical application. This study may provide a guideline regarding to the use of glycerol for optimal diagnostic and therapeutic effects in dermatology.

  16. Tunable optical limiting optofluidic device filled with graphene oxide dispersion in ethanol

    PubMed Central

    Fang, Chaolong; Dai, Bo; Hong, Ruijin; Tao, Chunxian; Wang, Qi; Wang, Xu; Zhang, Dawei; Zhuang, Songlin

    2015-01-01

    An optofluidic device with tunable optical limiting property is proposed and demonstrated. The optofluidic device is designed for adjusting the concentration of graphene oxide (GO) in the ethanol solution and fabricated by photolithography technique. By controlling the flow rate ratio of the injection, the concentration of GO can be precisely adjusted so that the optical nonlinearity can be changed. The nonlinear optical properties and dynamic excitation relaxation of the GO/ethanol solution are investigated by using Z-scan and pump-probe measurements in the femtosecond regime within the 1.5 μm telecom band. The GO/ethanol solution presents ultrafast recovery time. Besides, the optical limiting property is in proportion to the concentration of the solution. Thus, the threshold power and the saturated power of the optical limiting property can be simply and efficiently manipulated by controlling the flow rate ratio of the injection. Furthermore, the amplitude regeneration is demonstrated by employing the proposed optofluidic device. The signal quality of intensity-impaired femtosecond pulse is significantly improved. The optofluidic device is compact and has long interaction length of optical field and nonlinear material. Heat can be dissipated in the solution and nonlinear material is isolated from other optical components, efficiently avoiding thermal damage and mechanical damage. PMID:26477662

  17. Use of an optical clearing agent to enhance the visibility of subsurface structures and lesions from tooth occlusal surfaces

    NASA Astrophysics Data System (ADS)

    Kang, Hobin; Darling, Cynthia L.; Fried, Daniel

    2016-08-01

    The purpose of this study is to show that optical clearing agents can be used to increase the visibility of deeply penetrating occlusal lesions that have reached the underlying dentin and spread laterally under the enamel. Previous studies have shown that high refractive index fluids can increase the contrast of caries lesions. Extracted teeth with natural occlusal lesions were imaged with optical coherence tomography (OCT) with and without the addition of a transparent vinyl polysiloxane impression material (VPS) currently used in vivo. The relative intensity of the reflectivity from the underlying lesion area for each sample was measured before and after application of the VPS. Lesion presence was confirmed with polarized light microscopy and microradiography. Application of VPS significantly increased (P<0.0001) the integrated reflectivity of subsurface dentinal lesions. This study shows that optical clearing agents can be used to increase the optical penetration and the visibility of subsurface lesions and the dentinal-enamel junction under sound and demineralized enamel in OCT images.

  18. The Gaia Catalogue Second Data Release and Its Implications to Optical Observations of Man-Made Earth Orbiting Objects

    NASA Technical Reports Server (NTRS)

    Frith, James M.; Buckalew, Brent A.; Cowardin, Heather M.; Lederer, Susan M.

    2018-01-01

    The Gaia catalogue second data release and its implications to optical observations of man-made Earth orbiting objects. Abstract and not the Final Paper is attached. The Gaia spacecraft was launched in December 2013 by the European Space Agency to produce a three-dimensional, dynamic map of objects within the Milky Way. Gaia's first year of data was released in September 2016. Common sources from the first data release have been combined with the Tycho-2 catalogue to provide a 5 parameter astrometric solution for approximately 2 million stars. The second Gaia data release is scheduled to come out in April 2018 and is expected to provide astrometry and photometry for more than 1 billion stars, a subset of which with a the full 6 parameter astrometric solution (adding radial velocity) and positional accuracy better than 0.002 arcsec (2 mas). In addition to precise astrometry, a unique opportunity exists with the Gaia catalogue in its production of accurate, broadband photometry using the Gaia G filter. In the past, clear filters have been used by various groups to maximize likelihood of detection of dim man-made objects but these data were very difficult to calibrate. With the second release of the Gaia catalogue, a ground based system utilizing the G band filter will have access to 1.5 billion all-sky calibration sources down to an accuracy of 0.02 magnitudes or better. In this talk, we will discuss the advantages and practicalities of implementing the Gaia filters and catalogue into data pipelines designed for optical observations of man-made objects.

  19. Scattering from a cylindrical reflector: modified theory of physical optics solution.

    PubMed

    Yalçin, Ugur

    2007-02-01

    The problem of scattering from a perfectly conducting cylindrical reflector is examined with the method of the modified theory of physical optics. In this technique the physical optics currents are modified by using a variable unit vector on the scatterer's surface. These current components are obtained for the reflector, which is fed by an offset electric line source. The scattering integral is expressed by using these currents and evaluated asymptotically with the stationary phase method. The results are compared numerically by using physical optics theory, geometrical optics diffraction theory, and the exact solution of the Helmholtz equation. It is found that the modified theory of physical optics scattering field equations agrees with the geometrical optics diffraction theory and the exact solution of the Helmholtz equation.

  20. Effect of solvent volume on the physical properties of aluminium doped nanocrystalline zinc oxide thin films deposited using a simplified spray pyrolysis technique

    NASA Astrophysics Data System (ADS)

    Jabena Begum, N.; Mohan, R.; Ravichandran, K.

    2013-01-01

    Aluminium doped zinc oxide (AZO) thin films were deposited by employing a low cost and simplified spray technique using a perfume atomizer from starting solutions having different volumes (10, 20, … , 50 mL) of solvent. The effect of solvent volume on the structural, electrical, optical, photoluminescence (PL) and surface morphological properties was studied. The electrical resistivity of the AZO films is remarkably influenced by the variation in the solvent volume. The X-ray diffraction profiles clearly showed that all the films have preferential orientation along the (0 0 2) plane irrespective of the solvent volume. The crystallite size was found to be in the nano range of 35-46 nm. The optical transmittance in the visible region is desirably high (>85%). The AFM images show columnar morphology with varying grain size. The PL studies revealed that the AZO film deposited from 50 mL of solvent volume has good quality with lesser defect density.

  1. Note on the coupled oscillator model solutions in crystalline optical activity

    NASA Astrophysics Data System (ADS)

    Vyšín, I.; Ríha, J.; Svácková, K.

    2006-06-01

    Many methods have been used in the crystalline optical activity solution, among them the traditional method of coupled oscillators. The two coupled oscillator model was first solved by Chandrasekhar, and the most general dispersion relations for the crystalline optical activity can be obtained from its next extensions. However, the Chandrasekhar solution method seems to be based on a mistake in the computations. For this reason, the solution of a more complicated model of coupled oscillators which better corresponds to the structure of real crystals using the Condon relations is presented. This solution leads to the conclusion that, although it is possible to object to the Chandrasekhar solution method, the form of his final dispersion relations is correct. On the other hand, the dispersion relations following from the solution of more complicated coupled oscillator models are more convenient for the interpretation of the crystalline optical activity experimental data, which is demonstrated in examples of crystals of tellurium and benzil.

  2. Characterization of photoacoustic sources in tissue using time domain measurements

    NASA Astrophysics Data System (ADS)

    Viator, John Andrew

    Photoacoustic phenomenon in tissue and tissue phantoms is investigated with the particular goal of discrimination of diseased and healthy tissue. Propagation of broadband photoacoustic sources in tissue phantoms is studied with emphasis on attenuation, dispersion, and diffraction. Attenuation of photoacoustic waves induced by a circular laser spot on an absorber/air interface is modeled by the on-axis approximation of the acoustic field of a baffled piston source. Dispersion is studied in a diffraction free situation, where the disk of irradiation was created by a 5 mm laser spot on a 200 cm -1 solution. The genesis of diffraction in an absorbing solution was displayed by showing the merging of a boundary wave with a plane wave from a circular laser spot on an absorbing solution. Depth profiling of absorbing tissue phantoms and stained tissue was shown using a photoacoustic method. Acrylamide gels with layers of different optical absorption and stained elastin biomaterials were irradiated with stress confined laser pulses. The resulting acoustic waves were detected with a lithium niobate wideband acoustic transducer and processed in an algorithm to determine absorption coefficient as a function of depth. Spherical photoacoustic sources were generated in optically clear and turbid tissue phantoms. Propagation time and acoustic pulse duration were used to determine location and size, respectively. The photoacoustic sources were imaged using a multiplicative backprojection scheme. Image sources from acoustic boundaries were detected and dipole sources were detected and imaged. Finally an endoscopic photoacoustic probe was designed, built, and tested for use in determining treatment depth after palliative photodynamic therapy of esophageal cancer. The probe was less than 2.5 mm in diameter and consisted of a side firing 600 mum optical fiber to deliver laser energy and a 890 mum diameter, side viewing piezoelectric detector. The sensitivity of the probe was determined. The probe was also tested on coagulated and non-coagulated liver, ex vivo and on normally perfused and underperfused human skin, in vivo.

  3. Acousto-Optic Beam Sampler, Part 2. Green’s Function Solution to Acousto-Optic Interaction Problem.

    DTIC Science & Technology

    This part of the ’ Acousto - Optic Beam Sampler,’ series lays down the formalism behind the Green’s function integral approach to solving the acousto ... optic scattering problem. The advantage of this formulation which is applicable to gases is shown through developing the solution to the scattering

  4. Non-destructive optical clearing technique enhances optical coherence tomography (OCT) for real-time, 3D histomorphometry of brain tissue (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Paul, Akshay; Chang, Theodore H.; Chou, Li-Dek; Ramalingam, Tirunelveli S.

    2016-03-01

    Evaluation of neurodegenerative disease often requires examination of brain morphology. Volumetric analysis of brain regions and structures can be used to track developmental changes, progression of disease, and the presence of transgenic phenotypes. Current standards for microscopic investigation of brain morphology are limited to detection of superficial structures at a maximum depth of 300μm. While histological techniques can provide detailed cross-sections of brain structures, they require complicated tissue preparation and the ultimate destruction of the sample. A non-invasive, label-free imaging modality known as Optical Coherence Tomography (OCT) can produce 3-dimensional reconstructions through high-speed, cross-sectional scans of biological tissue. Although OCT allows for the preservation of intact samples, the highly scattering and absorbing properties of biological tissue limit imaging depth to 1-2mm. Optical clearing agents have been utilized to increase imaging depth by index matching and lipid digestion, however, these contemporary techniques are expensive and harsh on tissues, often irreversibly denaturing proteins. Here we present an ideal optical clearing agent that offers ease-of-use and reversibility. Similar to how SeeDB has been effective for microscopy, our fructose-based, reversible optical clearing technique provides improved OCT imaging and functional immunohistochemical mapping of disease. Fructose is a natural, non-toxic sugar with excellent water solubility, capable of increasing tissue transparency and reducing light scattering. We will demonstrate the improved depth-resolving performance of OCT for enhanced whole-brain imaging of normal and diseased murine brains following a fructose clearing treatment. This technique potentially enables rapid, 3-dimensional evaluation of biological tissues at axial and lateral resolutions comparable to histopathology.

  5. Planar integrated optics, a new solution in optical instrumentation

    NASA Astrophysics Data System (ADS)

    Haguenauer, P.

    2017-11-01

    Planar integrated optics present an attractive solution for future instrumentation, both in ground and space based applications. The technologies used in the manufacturing of such components, supported by research laboratories as well as industries, are mature enough to provide complex devices.

  6. Freeform Optics: current challenges for future serial production

    NASA Astrophysics Data System (ADS)

    Schindler, C.; Köhler, T.; Roth, E.

    2017-10-01

    One of the major developments in optics industry recently is the commercial manufacturing of freeform surfaces for optical mid- and high performance systems. The loss of limitation on rotational symmetry enables completely new optical design solutions - but causes completely new challenges for the manufacturer too. Adapting the serial production from radial-symmetric to freeform optics cannot be done just by the extension of machine capabilities and software for every process step. New solutions for conventional optics productions or completely new process chains are necessary.

  7. Optically Activated Exciplex Shutter/Attenuator.

    DTIC Science & Technology

    radiation of a certain wavelength to excite a bi-molecular exciplex solution. The exciplex solution reacts to a range of radiation wavelengths whereas...optical elements prevent passage of radiation below and above the operative range of an exciplex solution such as anthracene and diethylaniline.

  8. Optical signature of nerve tissue-Exploratory ex vivo study comparing optical, histological, and molecular characteristics of different adipose and nerve tissues.

    PubMed

    Balthasar, Andrea J R; Bydlon, Torre M; Ippel, Hans; van der Voort, Marjolein; Hendriks, Benno H W; Lucassen, Gerald W; van Geffen, Geert-Jan; van Kleef, Maarten; van Dijk, Paul; Lataster, Arno

    2018-05-14

    During several anesthesiological procedures, needles are inserted through the skin of a patient to target nerves. In most cases, the needle traverses several tissues-skin, subcutaneous adipose tissue, muscles, nerves, and blood vessels-to reach the target nerve. A clear identification of the target nerve can improve the success of the nerve block and reduce the rate of complications. This may be accomplished with diffuse reflectance spectroscopy (DRS) which can provide a quantitative measure of the tissue composition. The goal of the current study was to further explore the morphological, biological, chemical, and optical characteristics of the tissues encountered during needle insertion to improve future DRS classification algorithms. To compare characteristics of nerve tissue (sciatic nerve) and adipose tissues, the following techniques were used: histology, DRS, absorption spectrophotometry, high-resolution magic-angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy, and solution 2D 13 C- 1 H heteronuclear single-quantum coherence spectroscopy. Tissues from five human freshly frozen cadavers were examined. Histology clearly highlights a higher density of cellular nuclei, collagen, and cytoplasm in fascicular nerve tissue (IFAS). IFAS showed lower absorption of light around 1200 nm and 1750 nm, higher absorption around 1500 nm and 2000 nm, and a shift in the peak observed around 1000 nm. DRS measurements showed a higher water percentage and collagen concentration in IFAS and a lower fat percentage compared to all other tissues. The scattering parameter (b) was highest in IFAS. The HR-MAS NMR data showed three extra chemical peak shifts in IFAS tissue. Collagen, water, and cellular nuclei concentration are clearly different between nerve fascicular tissue and other adipose tissue and explain some of the differences observed in the optical absorption, DRS, and HR-NMR spectra of these tissues. Some differences observed between fascicular nerve tissue and adipose tissues cannot yet be explained but may be helpful in improving the discriminatory capabilities of DRS in anesthesiology procedures. Lasers Surg. Med. 9999:1-13, 2018. © 2018 The Authors. Lasers in Surgery and Medicine Published by Wiley Periodicals, Inc. © 2018 The Authors. Lasers in Surgery and Medicine Published by Wiley Periodicals, Inc.

  9. Real-time optical laboratory solution of parabolic differential equations

    NASA Technical Reports Server (NTRS)

    Casasent, David; Jackson, James

    1988-01-01

    An optical laboratory matrix-vector processor is used to solve parabolic differential equations (the transient diffusion equation with two space variables and time) by an explicit algorithm. This includes optical matrix-vector nonbase-2 encoded laboratory data, the combination of nonbase-2 and frequency-multiplexed data on such processors, a high-accuracy optical laboratory solution of a partial differential equation, new data partitioning techniques, and a discussion of a multiprocessor optical matrix-vector architecture.

  10. Modulation stability and dispersive optical soliton solutions of higher order nonlinear Schrödinger equation and its applications in mono-mode optical fibers

    NASA Astrophysics Data System (ADS)

    Arshad, Muhammad; Seadawy, Aly R.; Lu, Dianchen

    2018-01-01

    In mono-mode optical fibers, the higher order non-linear Schrödinger equation (NLSE) describes the propagation of enormously short light pulses. We constructed optical solitons and, solitary wave solutions of higher order NLSE mono-mode optical fibers via employing modified extended mapping method which has important applications in Mathematics and physics. Furthermore, the formation conditions are also given on parameters in which optical bright and dark solitons can exist for this media. The moment of the obtained solutions are also given graphically, that helps to realize the physical phenomena's of this model. The modulation instability analysis is utilized to discuss the model stability, which verifies that all obtained solutions are exact and stable. Many other such types of models arising in applied sciences can also be solved by this reliable, powerful and effective method. The method can also be functional to other sorts of higher order nonlinear problems in contemporary areas of research.

  11. Center for Adaptive Optics | Software

    Science.gov Websites

    Center for Adaptive Optics A University of California Science and Technology Center home Adaptive Optics Software The Center for Adaptive Optics acts as a clearing house for distributing Software to Institutes it gives specialists in Adaptive Optics a place to distribute their software. All software is

  12. Spatial localization and temporal analysis of optical property fluctuations by multiplexed near-infrared photon density waves in turbid media: In vitro and in vivo studies

    NASA Astrophysics Data System (ADS)

    Filiaci, Mattia Emidio

    2001-12-01

    In recent years the application of near infrared non- invasive methods for medical diagnostics and clinical studies has grown rapidly. The ease of use, low cost and portability of these methods is a clear advantage over other techniques such as MRI. The limitations in detection of optical property inhomogeneities in tissues, such as tumors or hematomas, is due to the diffusive, highly scattering nature of near infrared light propagation. I have studied and developed methods to improve the spatial localization of these inhomogeneities in biological tissues, especially for the application of functional studies of the human brain in vivo. Recently much attention has been given to the study of the processes in the human brain that lead to the changing of the optical parameters that characterize the tissue, measured by our frequency-domain instrumentation. These processes have been divided into two main categories with different time-scales. The slower one is mostly due to the fluctuations in the absorption coefficient caused by oxy- and deoxy-hemoglobin changes in the tissue. The temporal analysis of the signal resulting from this process is studied in detail, and I also introduce a time-series data analysis technique that has not been applied to this field before but was introduced in another area very recently. The faster time-scale process has been attributed to the electrochemical excitation of the individual neurons in the brain that have been observed to cause a change in the scattering coefficient of the tissue. This is the other primary parameter that is measured by our frequency domain instrument. However, before this work it has not been clear how to go about to better localize these smaller fluctuations. I present a novel idea for improving spatial localization of macroscopic optical parameter fluctuations, and study the characteristics of this optical probe design using analytical solutions to the diffusion equation and Monte Carlo simulations that more appropriately represent the volume of excitation of the cortex neurons.

  13. The Community Cloud retrieval for CLimate (CC4CL) - Part 2: The optimal estimation approach

    NASA Astrophysics Data System (ADS)

    McGarragh, Gregory R.; Poulsen, Caroline A.; Thomas, Gareth E.; Povey, Adam C.; Sus, Oliver; Stapelberg, Stefan; Schlundt, Cornelia; Proud, Simon; Christensen, Matthew W.; Stengel, Martin; Hollmann, Rainer; Grainger, Roy G.

    2018-06-01

    The Community Cloud retrieval for Climate (CC4CL) is a cloud property retrieval system for satellite-based multispectral imagers and is an important component of the Cloud Climate Change Initiative (Cloud_cci) project. In this paper we discuss the optimal estimation retrieval of cloud optical thickness, effective radius and cloud top pressure based on the Optimal Retrieval of Aerosol and Cloud (ORAC) algorithm. Key to this method is the forward model, which includes the clear-sky model, the liquid water and ice cloud models, the surface model including a bidirectional reflectance distribution function (BRDF), and the "fast" radiative transfer solution (which includes a multiple scattering treatment). All of these components and their assumptions and limitations will be discussed in detail. The forward model provides the accuracy appropriate for our retrieval method. The errors are comparable to the instrument noise for cloud optical thicknesses greater than 10. At optical thicknesses less than 10 modeling errors become more significant. The retrieval method is then presented describing optimal estimation in general, the nonlinear inversion method employed, measurement and a priori inputs, the propagation of input uncertainties and the calculation of subsidiary quantities that are derived from the retrieval results. An evaluation of the retrieval was performed using measurements simulated with noise levels appropriate for the MODIS instrument. Results show errors less than 10 % for cloud optical thicknesses greater than 10. Results for clouds of optical thicknesses less than 10 have errors up to 20 %.

  14. Optical soliton solutions for the higher-order dispersive cubic-quintic nonlinear Schrödinger equation

    NASA Astrophysics Data System (ADS)

    Inc, Mustafa; Yusuf, Abdullahi; Aliyu, Aliyu Isa; Baleanu, Dumitru

    2017-12-01

    In this paper, we analyze new optical soliton solutions to the higher-order dispersive cubic-quintic nonlinear Schrödinger equation (NLSE) using three integration schemes. The schemes used in this paper are modified tanh-coth (MTC), extended Jacobi elliptic function expansion (EJEF), and two variable (G‧ / G , 1 / G) -expansion methods. We obtain new solutions that to the best of our knowledge do not exist previously. The obtained solutions includes bright, dark, combined bright-dark, singular as well as periodic waves solitons. The obtained solutions may be used to explain and understand the physical nature of the wave spreads in the most dispersive optical medium. Some interesting figures for the physical interpretation of the obtained solutions are also presented.

  15. Measurements of spectral responses for developing fiber-optic pH sensor

    NASA Astrophysics Data System (ADS)

    Yoo, Wook Jae; Heo, Ji Yeon; Jang, Kyoung Won; Seo, Jeong Ki; Moon, Jin Soo; Park, Jang-Yeon; Park, Byung Gi; Cho, Seunghyun; Lee, Bongsoo

    2011-01-01

    In this study, we have fabricated a fiber-optic pH sensor, which is composed of a light source, a pH-sensing probe, plastic optical fibers and a spectrometer, for determining the degree of infection by Helicobacter pylori in the stomach. As pH indicators, phenol red and m-cresol purple are used, and pH liquid solutions are prepared by mixing phenol red or m-cresol purple solutions and various kinds of pH buffer solutions. The light emitted by a light source is guided by plastic optical fibers to the pH liquid solution, and the optical characteristic of a reflected light is changed according to the color variations of the pH indicator in the pH-sensing probe. Therefore, we have measured the intensities and wavelength shifts of the reflected lights, which change according to the color variations of indicators at different pH values, by using a spectrometer for spectral analysis. Also, the relationships between the pH values of liquid solutions and the optical properties of the modulated lights are obtained on the basis of the changes of the colors of indicators.

  16. Optical high acidity sensor

    DOEpatents

    Jorgensen, Betty S.; Nekimken, Howard L.; Carey, W. Patrick; O'Rourke, Patrick E.

    1997-01-01

    An apparatus and method for determining acid concentrations in solutions having acid concentrations of from about 0.1 Molar to about 16 Molar is disclosed. The apparatus includes a chamber for interrogation of the sample solution, a fiber optic light source for passing light transversely through the chamber, a fiber optic collector for receiving the collimated light after transmission through the chamber, a coating of an acid resistant polymeric composition upon at least one fiber end or lens, the polymeric composition in contact with the sample solution within the chamber and having a detectable response to acid concentrations within the range of from about 0.1 Molar to about 16 Molar, a measurer for the response of the polymeric composition in contact with the sample solution, and, a comparer of the measured response to predetermined standards whereby the acid molarity of the sample solution within the chamber can be determined. Preferably, a first lens is attached to the end of the fiber optic light source, the first lens adapted to collimate light from the fiber optic light source, and a second lens is attached to the end of the fiber optic collector for focusing the collimated light after transmission through the chamber.

  17. Optical high acidity sensor

    DOEpatents

    Jorgensen, B.S.; Nekimken, H.L.; Carey, W.P.; O`Rourke, P.E.

    1997-07-22

    An apparatus and method for determining acid concentrations in solutions having acid concentrations of from about 0.1 Molar to about 16 Molar is disclosed. The apparatus includes a chamber for interrogation of the sample solution, a fiber optic light source for passing light transversely through the chamber, a fiber optic collector for receiving the collimated light after transmission through the chamber, a coating of an acid resistant polymeric composition upon at least one fiber end or lens, the polymeric composition in contact with the sample solution within the chamber and having a detectable response to acid concentrations within the range of from about 0.1 Molar to about 16 Molar, a measurer for the response of the polymeric composition in contact with the sample solution, and a comparer of the measured response to predetermined standards whereby the acid molarity of the sample solution within the chamber can be determined. Preferably, a first lens is attached to the end of the fiber optic light source, the first lens adapted to collimate light from the fiber optic light source, and a second lens is attached to the end of the fiber optic collector for focusing the collimated light after transmission through the chamber. 10 figs.

  18. Use of an optical clearing agent to enhance the visibility of subsurface structures and lesions from tooth occlusal surfaces

    PubMed Central

    Kang, Hobin; Darling, Cynthia L.; Fried, Daniel

    2016-01-01

    Abstract. The purpose of this study is to show that optical clearing agents can be used to increase the visibility of deeply penetrating occlusal lesions that have reached the underlying dentin and spread laterally under the enamel. Previous studies have shown that high refractive index fluids can increase the contrast of caries lesions. Extracted teeth with natural occlusal lesions were imaged with optical coherence tomography (OCT) with and without the addition of a transparent vinyl polysiloxane impression material (VPS) currently used in vivo. The relative intensity of the reflectivity from the underlying lesion area for each sample was measured before and after application of the VPS. Lesion presence was confirmed with polarized light microscopy and microradiography. Application of VPS significantly increased (P<0.0001) the integrated reflectivity of subsurface dentinal lesions. This study shows that optical clearing agents can be used to increase the optical penetration and the visibility of subsurface lesions and the dentinal–enamel junction under sound and demineralized enamel in OCT images. PMID:27071709

  19. 77 FR 34417 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated: Notice of Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Outsourcing Solutions, Inc. (``Apex Clearing'') as a CBOE and CBSX Trading Permit Holder, subject to Apex... applicable to CBSX, including several rules in Chapter 3 of the CBOE rules related to the application process...'').\\4\\ \\3\\ Prior to the Transaction, Apex Clearing's name was Ridge Clearing & Outsourcing Solutions...

  20. Multispectral and colour analysis for ubiquinone solutions and biological samples

    NASA Astrophysics Data System (ADS)

    Timofeeva, Elvira O.; Gorbunova, Elena V.; Chertov, Aleksandr N.

    2017-02-01

    An oxidative damage in cell structures is a basis of most mechanisms that lead to health diseases and senescence of human body. The presence of antioxidant issues such as redox potential imbalance in human body is a very important question for modern clinical diagnostics. Implementation of multispectral and colour analysis of the human skin into optical diagnostics of such wide distributed in a human body antioxidant as ubiquinone can be one of the steps for development of the device with a view to clinical diagnostics of redox potential or quality control of the cosmetics. The recording of multispectral images of the hand skin with monochromatic camera and a set of coloured filters was provided in the current research. Recording data of the multispectral imaging technique was processed using principal component analysis. Also colour characteristics of the skin before and after the skin treatment with facial mask which contains ubiquinone were calculated. The results of the mask treatment were compared with the treatment using oily ubiquinone solution. Despite the fact that results did not give clear explanation about healthy skin or skin stressed by reactive oxygen species, methods which were described in this research are able to identify how skin surface is changing after the antioxidant treatment. In future it is important to provide biomedical tests during the optical tests of the human skin.

  1. Developing the OEIC solutions using two section light-emitting transistor

    NASA Astrophysics Data System (ADS)

    Liang, Shan-Fong; Hsu, Yuan-Fu; Cheng, Gong-Sheng; Wu, Chao-Hsin

    2016-02-01

    An integrated on-chip optical device composed of a multiple quantum-well light-emitter and photodetector in the lightemitting transistor (LET) platform is fabricated. The two devices are 400 μm in length and electrically isolated by dry etching with 4.9 μm gap. The two facets are formed by cleaving for optical output. In this report, we discuss the characteristics of the two-section device and demonstrate the optical detection by the heterojunction phototransistor (HPT) under different operation points (IB and VCE) and injected optical powers. The collector current of the HPT is 74.88 mA without illumination and 83.87 mA under illumination of 7.46μW at VCE = 3 V and IB = 12 mA, which exhibits 12% increment. The responsivity of the InGaP/GaAs HPT can reach to 711.74 A/W. At the electrical modulation bandwidth of phototransistor fT is enhanced from 1.4 GHz to 1.51 GHz under illumination. This is attributed to the Franz-Keldysh photon-assisted absorption at base-collector junction of light-emitting transistor, which produces additional holes and electrons to enhance the current gain. Through the analysis of small-signal equivalent circuit models, we can show the transit time by de-embedding the circuit parasitic effect. Extracting those parameters can clearly know the thermionic emission lifetime in the quantum well.

  2. Dispersive optical soliton solutions for higher order nonlinear Sasa-Satsuma equation in mono mode fibers via new auxiliary equation method

    NASA Astrophysics Data System (ADS)

    Khater, Mostafa M. A.; Seadawy, Aly R.; Lu, Dianchen

    2018-01-01

    In this research, we apply new technique for higher order nonlinear Schrödinger equation which is representing the propagation of short light pulses in the monomode optical fibers and the evolution of slowly varying packets of quasi-monochromatic waves in weakly nonlinear media that have dispersion. Nonlinear Schrödinger equation is one of the basic model in fiber optics. We apply new auxiliary equation method for nonlinear Sasa-Satsuma equation to obtain a new optical forms of solitary traveling wave solutions. Exact and solitary traveling wave solutions are obtained in different kinds like trigonometric, hyperbolic, exponential, rational functions, …, etc. These forms of solutions that we represent in this research prove the superiority of our new technique on almost thirteen powerful methods. The main merits of this method over the other methods are that it gives more general solutions with some free parameters.

  3. Noninvasively Imaging Subcutaneous Tumor Xenograft by a Handheld Raman Detector, with the Assistance of an Optical Clearing Agent.

    PubMed

    Zhang, Yunfei; Liu, Haoran; Tang, Jiali; Li, Zhuoyun; Zhou, Xingyu; Zhang, Ren; Chen, Liang; Mao, Ying; Li, Cong

    2017-05-31

    A handheld Raman detector with operational convenience, high portability, and rapid acquisition rate has been applied in clinics for diagnostic purposes. However, the inherent weakness of Raman scattering and strong scattering of the turbid tissue restricts its utilization to superficial locations. To extend the applications of a handheld Raman detector to deep tissues, a gold nanostar-based surface-enhanced Raman scattering (SERS) nanoprobe with robust colloidal stability, a fingerprint-like spectrum, and extremely high sensitivity (5.0 fM) was developed. With the assistance of FPT, a multicomponent optical clearing agent (OCA) efficiently suppressing light scattering from the turbid dermal tissues, the handheld Raman detector noninvasively visualized the subcutaneous tumor xenograft with a high target-to-background ratio after intravenous injection of the gold nanostar-based SERS nanoprobe. To the best of our knowledge, this work is the first example to introduce the optical clearing technique in assisting SERS imaging in vivo. The combination of optical clearing technology and SERS is a promising strategy for the extension of the clinical applications of the handheld Raman detector from superficial tissues to subcutaneous or even deeper lesions that are usually "concealed" by the turbid dermal tissue.

  4. Evanescent Wave Absorption Based Fiber Sensor for Measuring Glucose Solution Concentration

    NASA Astrophysics Data System (ADS)

    Marzuki, Ahmad; Candra Pratiwi, Arni; Suryanti, Venty

    2018-03-01

    An optical fiber sensor based on evanescent wave absorption designed for measuring glucose solution consentration was proposed. The sensor was made to detect absorbance of various wavelength in the glucose solution. The sensing element was fabricated by side polishing of multimode polymer optical fiber to form a D-shape. The sensing element was immersed in different concentration of glucoce solution. As light propagated through the optical fiber, the evanescent wave interacted with the glucose solution. Light was absorbed by the glucose solution. The larger concentration the glucose solution has, the more the evanescent wave was absorbed in particular wavelenght. Here in this paper, light absorbtion as function of glucose concentration was measured as function of wavelength (the color of LED). We have shown that the proposed sensor can demonstrated an increase of light absorption as function of glucose concentration.

  5. Comparison of vapor formation of water at the solid/water interface to colloidal solutions using optically excited gold nanostructures.

    PubMed

    Baral, Susil; Green, Andrew J; Livshits, Maksim Y; Govorov, Alexander O; Richardson, Hugh H

    2014-02-25

    The phase transformation properties of liquid water to vapor is characterized by optical excitation of the lithographically fabricated single gold nanowrenches and contrasted to the phase transformation properties of gold nanoparticles located and optically excited in a bulk solution system [two and three dimensions]. The 532 nm continuous wave excitation of a single gold nanowrench results in superheating of the water to the spinodal decomposition temperature of 580 ± 20 K with bubble formation below the spinodal decomposition temperature being a rare event. Between the spinodal decomposition temperature and the boiling point liquid water is trapped into a metastable state because a barrier to vapor nucleation exists that must be overcome before the thermodynamically stable state is realized. The phase transformation for an optically heated single gold nanowrench is different from the phase transformation of optically excited colloidal gold nanoparticles solution where collective heating effects dominates and leads to the boiling of the solution exactly at the boiling point. In the solution case, the optically excited ensemble of nanoparticles collectively raises the ambient temperature of water to the boiling point where liquid is converted into vapor. The striking difference in the boiling properties of the single gold nanowrench and the nanoparticle solution system can be explained in terms of the vapor-nucleation mechanism, the volume of the overheated liquid, and the collective heating effect. The interpretation of the observed regimes of heating and vaporization is consistent with our theoretical modeling. In particular, we explain with our theory why the boiling with the collective heating in a solution requires 3 orders of magnitude less intensity compared to the case of optically driven single nanowrench.

  6. Preparation of polymeric diacetylene thin films for nonlinear optical applications

    NASA Technical Reports Server (NTRS)

    Frazier, Donald O. (Inventor); Mcmanus, Samuel P. (Inventor); Paley, Mark S. (Inventor); Donovan, David N. (Inventor)

    1995-01-01

    A method for producing polymeric diacetylene thin films having desirable nonlinear optical characteristics has been achieved by producing amorphous diacetylene polymeric films by simultaneous polymerization of diacetylene monomers in solution and deposition of polymerized diacetylenes on to the surface of a transparent substrate through which ultraviolet light has been transmitted. These amorphous polydiacetylene films produced by photo-deposition from solution possess very high optical quality and exhibit large third order nonlinear optical susceptibilities, such properties being suitable for nonlinear optical devices such as waveguides and integrated optics.

  7. Scanner OPC signatures: automatic vendor-to-vendor OPE matching

    NASA Astrophysics Data System (ADS)

    Renwick, Stephen P.

    2009-03-01

    As 193nm lithography continues to be stretched and the k1 factor decreases, optical proximity correction (OPC) has become a vital part of the lithographer's tool kit. Unfortunately, as is now well known, the design variations of lithographic scanners from different vendors cause them to have slightly different optical-proximity effect (OPE) behavior, meaning that they print features through pitch in distinct ways. This in turn means that their response to OPC is not the same, and that an OPC solution designed for a scanner from Company 1 may or may not work properly on a scanner from Company 2. Since OPC is not inexpensive, that causes trouble for chipmakers using more than one brand of scanner. Clearly a scanner-matching procedure is needed to meet this challenge. Previously, automatic matching has only been reported for scanners of different tool generations from the same manufacturer. In contrast, scanners from different companies have been matched using expert tuning and adjustment techniques, frequently requiring laborious test exposures. Automatic matching between scanners from Company 1 and Company 2 has remained an unsettled problem. We have recently solved this problem and introduce a novel method to perform the automatic matching. The success in meeting this challenge required three enabling factors. First, we recognized the strongest drivers of OPE mismatch and are thereby able to reduce the information needed about a tool from another supplier to that information readily available from all modern scanners. Second, we developed a means of reliably identifying the scanners' optical signatures, minimizing dependence on process parameters that can cloud the issue. Third, we carefully employed standard statistical techniques, checking for robustness of the algorithms used and maximizing efficiency. The result is an automatic software system that can predict an OPC matching solution for scanners from different suppliers without requiring expert intervention.

  8. Solution-Grown Rubrene Crystals as Radiation Detecting Devices

    DOE PAGES

    Carman, Leslie; Martinez, H. Paul; Voss, Lars; ...

    2017-01-11

    There has been increased interest in organic semiconductors over the last decade because of their unique properties. Of these, 5, 6, 11, 12-tetraphenylnaphthacene (rubrene) has generated the most interest because of its high charge carrier mobility. In this paper, large single crystals with a volume of ~1 cm 3 were grown from solution by a temperature reduction technique. The faceted crystals had flat surfaces and cm-scale, visually defect-free areas suitable for physical characterization. X-ray diffraction analysis indicates that solvent does not incorporate into the crystals and photoluminescence spectra are consistent with pristine, high-crystallinity rubrene. Furthermore, the response curve to pulsedmore » optical illumination indicates that the solution grown crystals are of similar quality to those grown by physical vapor transport, albeit larger. The good quality of these crystals in combination with the improvement of electrical contacts by application of conductive polymer on the graphite electrodes have led to the clear observation of alpha particles with these rubrene detectors. Finally, preliminary results with a 252Cf source generate a small signal with the rubrene detector and may demonstrate that rubrene can also be used for detecting high-energy neutrons.« less

  9. Influence of the relative optical air mass on ultraviolet erythemal irradiance

    NASA Astrophysics Data System (ADS)

    Antón, M.; Serrano, A.; Cancillo, M. L.; García, J. A.

    2009-12-01

    The main objective of this article is to analyze the relationship between the transmissivity for ultraviolet erythemal irradiance (UVER) and the relative optical air mass at Badajoz (Southwestern Spain). Thus, a power expression between both variables is developed, which analyses in detail how atmospheric transmission is influenced by the total ozone column (TOC) and the atmospheric clearness. The period of analysis extends from 2001 to 2005. The experimental results indicate that clearness conditions play an important role in the relationship between UVER transmissivity and the relative optical air mass, while the effect of TOC is much smaller for this data set. In addition, the results show that UVER transmissivity is more sensitive to changes in atmospheric clearness than to TOC variability. Changes in TOC values higher than 15% cause UVER trasnmissivity to vary between 14% and 22%, while changes between cloud-free and overcast conditions produce variations in UVER transmissivity between 68% and 74% depending on the relative optical air mass.

  10. Forward multiple scattering corrections as function of detector field of view

    NASA Astrophysics Data System (ADS)

    Zardecki, A.; Deepak, A.

    1983-06-01

    The theoretical formulations are given for an approximate method based on the solution of the radiative transfer equation in the small angle approximation. The method is approximate in the sense that an approximation is made in addition to the small angle approximation. Numerical results were obtained for multiple scattering effects as functions of the detector field of view, as well as the size of the detector's aperture for three different values of the optical depth tau (=1.0, 4.0 and 10.0). Three cases of aperture size were considered--namely, equal to or smaller or larger than the laser beam diameter. The contrast between the on-axis intensity and the received power for the last three cases is clearly evident.

  11. Care System Versus Transmitted Light Wavefront Pattern of Contact Lenses.

    PubMed

    Chiericati, Stefano; Borghesi, Alessandro; Cozza, Federica; Ferraro, Lorenzo; Acciarri, Maurizio; Farris, Stefano; Tavazzi, Silvia

    2017-05-01

    This article compares the optical performance of soft contact lenses (CLs) treated with multipurpose or hydrogen peroxide care systems. The investigated care systems were (1) 3% hydrogen peroxide solution Oxysept (Abbot Medical Optics, Abbott Park, IL) and (2) multipurpose solution Regard (Vita Research, Ariccia, Italy). Three types of silicone hydrogel CLs were studied (comfilcon A, lotrafilcon B, and balafilcon A), unworn and exposed for 30 times to the solutions, which were replaced every 8 hr. The optical performance of the CLs was evaluated through the on-eye transmitted light wavefront patterns by considering new CLs as references. The surface morphology of the CLs was investigated by scanning electron microscopy. Statistically significant modifications in the range 0.1 to 0.3 μm of Zernicke coefficients and modifications of the root mean square of the wavefront aberration function were found for CLs treated with multipurpose solution, in agreement with the observed modifications of the surface morphology. Statistically significant changes were also found after exposure to the hydrogen peroxide solution, but the variation of the Zernicke coefficients was found lower than 0.1 μm, thus being negligible in CL optical performances. In addition to disinfection ability and ocular surface reactions, CL care systems are different in solution-related CL optical performance. Multipurpose solutions may affect the CL surface morphology with significant modifications of the transmitted light wavefront pattern.

  12. TH-C-19A-05: Evaluation of a New Reusable 3D Dosimeter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Juang, T; Adamovics, J; Oldham, M

    Purpose: PRESAGE is a radiochromic plastic which has demonstrated strong potential for high resolution single-use 3D dosimetry. This study evaluates a new PRESAGE formulation (Presage-RU) in which the radiochromic response is reversible (the dosimeter optically clears after irradiation), enabling the potential for reusability. Methods: Presage-RU dose response and optical-clearing rates were evaluated in both small volume dosimeters (1×1×4.5cm) and a larger cylindrical dosimeter (8cm diameter, 4.5cm length). All dosimeters were allowed to fully optically clear in dark, room temperature conditions between irradiations. Dose response was determined by irradiating small volume samples from 0–8.0Gy and measuring change in optical density. Themore » cylindrical dosimeter was irradiated with a simple 4-field box plan (parallel opposed pairs of 4cm×4cm AP-PA beams and 2cm×4cm lateral beams) to 20Gy. High resolution 3D dosimetry was achieved utilizing optical-CT readout. Readings were tracked up to 14 days to characterize optical clearing. Results: Initial irradiation yielded a response of 0.0119△OD/(Gy*cm) while two subsequent reirradiations yielded a lower but consistent response of 0.0087△OD/(Gy*cm). Strong linearity of dose response was observed for all irradiations. In the large cylindrical dosimeter, the integral dose within the high dose region exhibited an exponential decay in signal over time (halflife= 23.9 hours), with the dosimeter effectively cleared (0.04% of the initial signal) after 10 days. Subsequent irradiation resulted in 19.5% lower initial signal but demonstrated that the exponential clearing rate remained consistent. Results of additional subsequent irradiations will also be presented. Conclusion: This work introduces a new re-usable radiochromic dosimeter (Presage-RU) compatible with high resolution (sub-millimeter) 3D dosimetry. Sensitivity of the initial radiation was observed to be slightly higher than subsequent irradiations, but the clearing time remained constant, indicating the dosimeter can be re-used after 10 days. Presage-RU has potential to dramatically improve cost-effectiveness and thereby lower the barrier for implementing comprehensive, high resolution 3D dosimetry. John Adamovics is the president of Heuris Inc., which commercializes PRESAGE.« less

  13. Applications of Nano-optics.

    PubMed

    Zhou, Changhe; Fainman, Yeshaiahu; Sheng, Yunlong

    2011-11-01

    As nanoscale fabrication techniques advance, nano-optics continues to offer enabling solutions to numerous practical applications for information optics. This Applied Optics feature issue focuses on the Application of Nano-optics. © 2011 Optical Society of America

  14. Automatically high accurate and efficient photomask defects management solution for advanced lithography manufacture

    NASA Astrophysics Data System (ADS)

    Zhu, Jun; Chen, Lijun; Ma, Lantao; Li, Dejian; Jiang, Wei; Pan, Lihong; Shen, Huiting; Jia, Hongmin; Hsiang, Chingyun; Cheng, Guojie; Ling, Li; Chen, Shijie; Wang, Jun; Liao, Wenkui; Zhang, Gary

    2014-04-01

    Defect review is a time consuming job. Human error makes result inconsistent. The defects located on don't care area would not hurt the yield and no need to review them such as defects on dark area. However, critical area defects can impact yield dramatically and need more attention to review them such as defects on clear area. With decrease in integrated circuit dimensions, mask defects are always thousands detected during inspection even more. Traditional manual or simple classification approaches are unable to meet efficient and accuracy requirement. This paper focuses on automatic defect management and classification solution using image output of Lasertec inspection equipment and Anchor pattern centric image process technology. The number of mask defect found during an inspection is always in the range of thousands or even more. This system can handle large number defects with quick and accurate defect classification result. Our experiment includes Die to Die and Single Die modes. The classification accuracy can reach 87.4% and 93.3%. No critical or printable defects are missing in our test cases. The missing classification defects are 0.25% and 0.24% in Die to Die mode and Single Die mode. This kind of missing rate is encouraging and acceptable to apply on production line. The result can be output and reloaded back to inspection machine to have further review. This step helps users to validate some unsure defects with clear and magnification images when captured images can't provide enough information to make judgment. This system effectively reduces expensive inline defect review time. As a fully inline automated defect management solution, the system could be compatible with current inspection approach and integrated with optical simulation even scoring function and guide wafer level defect inspection.

  15. Controllable parabolic-cylinder optical rogue wave.

    PubMed

    Zhong, Wei-Ping; Chen, Lang; Belić, Milivoj; Petrović, Nikola

    2014-10-01

    We demonstrate controllable parabolic-cylinder optical rogue waves in certain inhomogeneous media. An analytical rogue wave solution of the generalized nonlinear Schrödinger equation with spatially modulated coefficients and an external potential in the form of modulated quadratic potential is obtained by the similarity transformation. Numerical simulations are performed for comparison with the analytical solutions and to confirm the stability of the rogue wave solution obtained. These optical rogue waves are built by the products of parabolic-cylinder functions and the basic rogue wave solution of the standard nonlinear Schrödinger equation. Such rogue waves may appear in different forms, as the hump and paw profiles.

  16. 3D imaging of optically cleared tissue using a simplified CLARITY method and on-chip microscopy

    PubMed Central

    Zhang, Yibo; Shin, Yoonjung; Sung, Kevin; Yang, Sam; Chen, Harrison; Wang, Hongda; Teng, Da; Rivenson, Yair; Kulkarni, Rajan P.; Ozcan, Aydogan

    2017-01-01

    High-throughput sectioning and optical imaging of tissue samples using traditional immunohistochemical techniques can be costly and inaccessible in resource-limited areas. We demonstrate three-dimensional (3D) imaging and phenotyping in optically transparent tissue using lens-free holographic on-chip microscopy as a low-cost, simple, and high-throughput alternative to conventional approaches. The tissue sample is passively cleared using a simplified CLARITY method and stained using 3,3′-diaminobenzidine to target cells of interest, enabling bright-field optical imaging and 3D sectioning of thick samples. The lens-free computational microscope uses pixel super-resolution and multi-height phase recovery algorithms to digitally refocus throughout the cleared tissue and obtain a 3D stack of complex-valued images of the sample, containing both phase and amplitude information. We optimized the tissue-clearing and imaging system by finding the optimal illumination wavelength, tissue thickness, sample preparation parameters, and the number of heights of the lens-free image acquisition and implemented a sparsity-based denoising algorithm to maximize the imaging volume and minimize the amount of the acquired data while also preserving the contrast-to-noise ratio of the reconstructed images. As a proof of concept, we achieved 3D imaging of neurons in a 200-μm-thick cleared mouse brain tissue over a wide field of view of 20.5 mm2. The lens-free microscope also achieved more than an order-of-magnitude reduction in raw data compared to a conventional scanning optical microscope imaging the same sample volume. Being low cost, simple, high-throughput, and data-efficient, we believe that this CLARITY-enabled computational tissue imaging technique could find numerous applications in biomedical diagnosis and research in low-resource settings. PMID:28819645

  17. Lasing eigenvalue problems: the electromagnetic modelling of microlasers

    NASA Astrophysics Data System (ADS)

    Benson, Trevor; Nosich, Alexander; Smotrova, Elena; Balaban, Mikhail; Sewell, Phillip

    2007-02-01

    Comprehensive microcavity laser models should account for several physical mechanisms, e.g. carrier transport, heating and optical confinement, coupled by non-linear effects. Nevertheless, considerable useful information can still be obtained if all non-electromagnetic effects are neglected, often within an additional effective-index reduction to an equivalent 2D problem, and the optical modes viewed as solutions of Maxwell's equations. Integral equation (IE) formulations have many advantages over numerical techniques such as FDTD for the study of such microcavity laser problems. The most notable advantages of an IE approach are computational efficiency, the correct description of cavity boundaries without stair-step errors, and the direct solution of an eigenvalue problem rather than the spectral analysis of a transient signal. Boundary IE (BIE) formulations are more economic that volume IE (VIE) ones, because of their lower dimensionality, but they are only applicable to the constant cavity refractive index case. The Muller BIE, being free of 'defect' frequencies and having smooth or integrable kernels, provides a reliable tool for the modal analysis of microcavities. Whilst such an approach can readily identify complex-valued natural frequencies and Q-factors, the lasing condition is not addressed directly. We have thus suggested using a Muller BIE approach to solve a lasing eigenvalue problem (LEP), i.e. a linear eigenvalue solution in the form of two real-valued numbers (lasing wavelength and threshold information) when macroscopic gain is introduced into the cavity material within an active region. Such an approach yields clear insight into the lasing thresholds of individual cavities with uniform and non-uniform gain, cavities coupled as photonic molecules and cavities equipped with one or more quantum dots.

  18. Dispersive optical soliton solutions for the hyperbolic and cubic-quintic nonlinear Schrödinger equations via the extended sinh-Gordon equation expansion method

    NASA Astrophysics Data System (ADS)

    Seadawy, Aly R.; Kumar, Dipankar; Chakrabarty, Anuz Kumar

    2018-05-01

    The (2+1)-dimensional hyperbolic and cubic-quintic nonlinear Schrödinger equations describe the propagation of ultra-short pulses in optical fibers of nonlinear media. By using an extended sinh-Gordon equation expansion method, some new complex hyperbolic and trigonometric functions prototype solutions for two nonlinear Schrödinger equations were derived. The acquired new complex hyperbolic and trigonometric solutions are expressed by dark, bright, combined dark-bright, singular and combined singular solitons. The obtained results are more compatible than those of other applied methods. The extended sinh-Gordon equation expansion method is a more powerful and robust mathematical tool for generating new optical solitary wave solutions for many other nonlinear evolution equations arising in the propagation of optical pulses.

  19. Application of chiral critical clusters to assymetric synthesis

    DOEpatents

    Ferrieri, Richard A.

    2002-01-01

    Disclosed is a composition, a method of making and a method of using critical clusters for asymmetric synthesis using substantially optically-pure chiral solvent molecules in a supercritical fluid. The solvent molecules are capable of forming a multipoint hydrogen bonded solvate as they encage at least one solute molecule. The encaged solute molecule is capable of reacting to form an optically active chiral center. In another aspect, there is disclosed a method of directing the position of bonding between a solute molecule and a ligand involving encaging the solute molecule and the ligand with polar solvent molecules in a supercritical fluid under conditions of temperature and pressure sufficient to change electric charge distribution in the solute molecule. In yet another aspect, disclosed is a method of making pharmaceutical compounds involving encaging a solute molecule, which is capable of forming a chiral center, and a ligand with polar solvent molecules in a supercritical fluid under conditions of temperature and pressure sufficient to change electric charge distribution of the solute molecule. The solute molecule and ligand are then reacted whereby the ligand bonds to the solute molecule forming a chiral center. Also disclosed is a method for racemic resolution using critical clusters involving encaging racemic mixtures of solute molecules with substantially optically-pure chiral solvent molecules in a supercritical fluid under conditions of temperature and pressure sufficient to form critical clusters. The solvent molecules are capable of multipoint hydrogen bonding with the solute molecules. The encaged solute molecules are then nonenzymatically reacted to enhance the optical purity of the solute molecules.

  20. Novel optical switch with a reconfigurable dielectric liquid droplet.

    PubMed

    Ren, Hongwen; Xu, Su; Ren, Daqiu; Wu, Shin-Tson

    2011-01-31

    We demonstrated a novel optical switch with a reconfigurable dielectric liquid droplet. The device consists of a clear liquid droplet (glycerol) surrounded by a black liquid (dye-doped liquid crystal). In the voltage-off state, the incident light passing through the clear liquid droplet is absorbed by the black liquid, resulting in a dark state. In the voltage-on state, the dome of the clear liquid droplet is uplifted by the dielectric force to form a light pipe which in turn transmits the incident light. Upon removing the voltage, the droplet recovers to its original shape and the switch is closed. We also demonstrated a red color light switch with ~10:1 contrast ratio and ~300 ms response time. Devices based on such an operation mechanism will find attractive applications in light shutter, tunable iris, variable optical attenuators, and displays.

  1. Tulip-form variable-curvature mirrors: interferometry and field compensation

    NASA Astrophysics Data System (ADS)

    Lemaitre, Gerard R.; Mazzanti, Silvio; Ferrari, Marc

    1998-07-01

    Active Optics methods are now capable to provide variable curvature mirrors (VCMs) having controlled sags in the focal range from f/(infinity) to f/2.5. Those development have been carried out by the authors for the optical path equalizer dedicated to each Mersenne focus of the VLTI. The basic principle is to use VCMs as cat's eye mirrors in each delay line in order to achieve field compensations at the recombined Mersenne focii. During the VLTI development phase, cycloid form VCMs controlled by air pressure have been performed with a 10(superscript -4) mirror sag resolution. The cycloid form has been selected for the VLTi delay lines. However, other analytical solutions from circular plates elasticity theory have been found. Two thickness distributions lead to tulip form VCMs controlled by a central force. One of them, using a lineic reaction at the edge is the object of this paper. Active optics design, construction features, test and experimental He-Ne interferograms obtained with 16mm boundary aperture and 10mm clear aperture are presented. The mean aspect-ratio of the tulip from VCM is d/t(subscript 0.5) approximately equals 60, providing a focal zoom range from f/(infinity) to f/2.5. The experiment is carried out form f/(infinity) to f/5.

  2. Optical assessment of tumor resection margins in the breast

    PubMed Central

    Brown, J. Quincy; Bydlon, Torre M.; Richards, Lisa M.; Yu, Bing; Kennedy, Stephanie A.; Geradts, Joseph; Wilke, Lee G.; Junker, Marlee; Gallagher, Jennifer; Barry, William; Ramanujam, Nimmi

    2011-01-01

    Breast conserving surgery, in which the breast tumor and surrounding normal tissue are removed, is the primary mode of treatment for invasive and in situ carcinomas of the breast, conditions that affect nearly 200,000 women annually. Of these nearly 200,000 patients who undergo this surgical procedure, between 20–70% of them may undergo additional surgeries to remove tumor that was left behind in the first surgery, due to the lack of intra-operative tools which can detect whether the boundaries of the excised specimens are free from residual cancer. Optical techniques have many attractive attributes which may make them useful tools for intra-operative assessment of breast tumor resection margins. In this manuscript, we discuss clinical design criteria for intra-operative breast tumor margin assessment, and review optical techniques appied to this problem. In addition, we report on the development and clinical testing of quantitative diffuse reflectance imaging (Q-DRI) as a potential solution to this clinical need. Q-DRI is a spectral imaging tool which has been applied to 56 resection margins in 48 patients at Duke University Medical Center. Clear sources of contrast between cancerous and cancer-free resection margins were identified with the device, and resulted in an overall accuracy of 75% in detecting positive margins. PMID:21544237

  3. Monitoring of interaction of low-frequency electric field with biological tissues upon optical clearing with optical coherence tomography.

    PubMed

    Peña, Adrián F; Doronin, Alexander; Tuchin, Valery V; Meglinski, Igor

    2014-08-01

    The influence of a low-frequency electric field applied to soft biological tissues ex vivo at normal conditions and upon the topical application of optical clearing agents has been studied by optical coherence tomography (OCT). The electro-kinetic response of tissues has been observed and quantitatively evaluated by the double correlation OCT approach, utilizing consistent application of an adaptive Wiener filtering and Fourier domain correlation algorithm. The results show that fluctuations, induced by the electric field within the biological tissues are exponentially increased in time. We demonstrate that in comparison to impedance measurements and the mapping of the temperature profile at the surface of the tissue samples, the double correlation OCT approach is much more sensitive to the changes associated with the tissues' electro-kinetic response. We also found that topical application of the optical clearing agent reduces the tissues' electro-kinetic response and is cooling the tissue, thus reducing the temperature induced by the electric current by a few degrees. We anticipate that dcOCT approach can find a new application in bioelectrical impedance analysis and monitoring of the electric properties of biological tissues, including the resistivity of high water content tissues and its variations.

  4. Quantitative analysis of dehydration in porcine skin for assessing mechanism of optical clearing

    NASA Astrophysics Data System (ADS)

    Yu, Tingting; Wen, Xiang; Tuchin, Valery V.; Luo, Qingming; Zhu, Dan

    2011-09-01

    Dehydration induced by optical clearing agents (OCAs) can improve tissue optical transmittance; however, current studies merely gave some qualitative descriptions. We develop a model to quantitatively evaluate water content with partial least-squares method based on the measurements of near-infrared reflectance spectroscopy and weight of porcine skin. Furthermore, a commercial spectrometer with an integrating sphere is used to measure the transmittance and reflectance of skin after treatment with different OCAs, and then the water content and optical properties of sample are calculated, respectively. The results show that both the reduced scattering coefficient and dehydration of skin decrease with prolongation of action of OCAs, but the relative change in former is larger than that in latter after a 60-min treatment. The absorption coefficient at 1450 nm decreases completely coincident with dehydration of skin. Further analysis illustrates that the correlation coefficient between the relative changes in the reduced scattering coefficient and dehydration is ~1 during the 60-min treatment of agents, but there is an extremely significant difference between the two parameters for some OCAs with more hydroxyl groups, especially, glycerol or D-sorbitol, which means that the dehydration is a main mechanism of skin optical clearing, but not the only mechanism.

  5. On the influence of lipid-induced optical anisotropy for the bioimaging of exo- or endocytosis with interference microscopic imaging.

    PubMed

    Marques, D; Miranda, A; Silva, A G; Munro, P R T; DE Beule, P A A

    2018-05-01

    Some implementations of interference microscopy imaging use digital holographic measurements of complex scattered fields to reconstruct three-dimensional refractive index maps of weakly scattering, semi-transparent objects, frequently encountered in biological investigations. Reconstruction occurs through application of the object scattering potential which assumes an isotropic refractive index throughout the object. Here, we demonstrate that this assumption can in some circumstances be invalid for biological imaging due to the presence of lipid-induced optical anisotropy. We show that the nanoscale organization of lipids in the observation of cellular endocytosis with polarized light induces a significant change in far-field scattering. We obtain this result by presenting a general solution to Maxwell's equations describing light scattering of core-shell particles near an isotropic substrate covered with an anisotropic thin film. This solution is based on an extension of the Bobbert-Vlieger solution for particle scattering near a substrate delivering an exact solution to the scattering problem in the near field as well as far field. By applying this solution to study light scattering by a lipid vesicle near a lipid bilayer, whereby the lipids are represented through a biaxial optical model, we conclude through ellipsometry concepts that effective amounts of lipid-induced optical anisotropy significantly alter far-field optical scattering in respect to an equivalent optical model that neglects the presence of optical anisotropy. © 2018 The Authors Journal of Microscopy © 2018 Royal Microscopical Society.

  6. The lymphatic mechanisms of brain cleaning: application of optical coherence tomography and fluorescence microscopy

    NASA Astrophysics Data System (ADS)

    Glushkovskaya-Semyachkina, O.; Abdurashitov, A.; Fedosov, I.; Namykin, A.; Pavlov, A.; Shirokov, A.; Shushunova, N.; Sindeeva, O.; Khorovodov, A.; Ulanova, M.; Sagatova, V.; Agranovich, I.; Bodrova, A.; Kurths, J.

    2018-04-01

    Here we studied the role of cerebral lymphatic system in the brain clearing using intraparenchymal injection of Evans Blue and gold nanorods assessed by optical coherent tomography and fluorescence microscopy. Our data clearly show that the cerebral lymphatic system plays an important role in the brain cleaning via meningeal lymphatic vessels but not cerebral veins. Meningeal lymphatic vessels transport fluid from the brain into the deep cervical node, which is the first anatomical "station" for lymph outflow from the brain. The lymphatic processes underlying brain clearing are more slowly vs. peripheral lymphatics. These results shed light on the lymphatic mechanisms responsible for brain clearing as well as interaction between the intra- and extracranial lymphatic compartment.

  7. Nonlinear tunneling of optical soliton in 3 coupled NLS equation with symbolic computation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mani Rajan, M.S., E-mail: senthilmanirajanofc@gmail.com; Mahalingam, A.; Uthayakumar, A.

    We investigated the soliton solution for N coupled nonlinear Schrödinger (CNLS) equations. These equations are coupled due to the cross-phase-modulation (CPM). Lax pair of this system is obtained via the Ablowitz–Kaup–Newell–Segur (AKNS) scheme and the corresponding Darboux transformation is constructed to derive the soliton solution. One and two soliton solutions are generated. Using two soliton solutions of 3 CNLS equation, nonlinear tunneling of soliton for both with and without exponential background has been discussed. Finally cascade compression of optical soliton through multi-nonlinear barrier has been discussed. The obtained results may have promising applications in all-optical devices based on optical solitons,more » study of soliton propagation in birefringence fiber systems and optical soliton with distributed dispersion and nonlinearity management. -- Highlights: •We consider the nonlinear tunneling of soliton in birefringence fiber. •3-coupled NLS (CNLS) equation with variable coefficients is considered. •Two soliton solutions are obtained via Darboux transformation using constructed Lax pair. •Soliton tunneling through dispersion barrier and well are investigated. •Finally, cascade compression of soliton has been achieved.« less

  8. An Analytical Model for the Evolution of the Protoplanetary Disks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khajenabi, Fazeleh; Kazrani, Kimia; Shadmehri, Mohsen, E-mail: f.khajenabi@gu.ac.ir

    We obtain a new set of analytical solutions for the evolution of a self-gravitating accretion disk by holding the Toomre parameter close to its threshold and obtaining the stress parameter from the cooling rate. In agreement with the previous numerical solutions, furthermore, the accretion rate is assumed to be independent of the disk radius. Extreme situations where the entire disk is either optically thick or optically thin are studied independently, and the obtained solutions can be used for exploring the early or the final phases of a protoplanetary disk evolution. Our solutions exhibit decay of the accretion rate as amore » power-law function of the age of the system, with exponents −0.75 and −1.04 for optically thick and thin cases, respectively. Our calculations permit us to explore the evolution of the snow line analytically. The location of the snow line in the optically thick regime evolves as a power-law function of time with the exponent −0.16; however, when the disk is optically thin, the location of the snow line as a function of time with the exponent −0.7 has a stronger dependence on time. This means that in an optically thin disk inward migration of the snow line is faster than an optically thick disk.« less

  9. Intraoral scanning systems - a current overview.

    PubMed

    Zimmermann, M; Mehl, A; Mörmann, W H; Reich, S

    2015-01-01

    There is no doubt today about the possibilities and potential of digital impression-taking with the aid of intraoral optical impression systems, and the past few years have seen a considerable increase in the range of optical intraoral scanners available on the market. On the strength of numerous innovations and a wider range of indications in orthodontics and implantology, intraoral scanning systems appear to be a highly promising development for the future. Digital impression-taking with intraoral scanners has already shown itself in some respects to be clearly superior to conventional impression- taking. Particularly worthy of mention is the versatile integration of digital impressions into diagnostic and treatment concepts to provide a customizable healthcare solution for the patient. It remains exciting to look forward to future developments that will allow us to observe digital impression-taking--as with other digital applications already established in everyday life--becoming firmly established in the routine of dentistry and dental technology. This article presents an overview of the benefits and limitations of digital impression-taking using intraoral scanning systems, and includes a summary of all the relevant intraoral scanners available on the market at present.

  10. Quantifying glucose permeability and enhanced light penetration in ex vivo human normal and cancerous esophagus tissues with optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Zhao, Q. L.; Si, J. L.; Guo, Z. Y.; Wei, H. J.; Yang, H. Q.; Wu, G. Y.; Xie, S. S.; Li, X. Y.; Guo, X.; Zhong, H. Q.; Li, L. Q.

    2011-01-01

    We report our pilot results on quantification of glucose (G) diffusion permeability in human normal esophagus and ESCC tissues in vitro by using OCT technique. The permeability coefficient of 40% aqueous solution of G was found to be (1.74±0.04)×10-5 cm/s in normal esophagus and (2.45±0.06)×10-5 cm/s in ESCC tissues. The results from this study indicate that ESCC tissues had a higher permeability coefficient compared to normal esophageal tissues, and the light penetration depths gradually increase with the increase of applied topically with G time for the normal esophageal and ESCC tissues. The results indicate that the permeability coefficient of G in cancer tissues was 1.41-fold than that in normal tissues, and the light penetration depth for the ESCC tissues is significantly smaller than that of normal esophagus tissues in the same time range. These results demonstrate that the optical clearing of normal and cancer esophagus tissues are improved after application of G.

  11. Perturbed dark and singular optical solitons in polarization preserving fibers by modified simple equation method

    NASA Astrophysics Data System (ADS)

    Yaşar, Emrullah; Yıldırım, Yakup; Zhou, Qin; Moshokoa, Seithuti P.; Ullah, Malik Zaka; Triki, Houria; Biswas, Anjan; Belic, Milivoj

    2017-11-01

    This paper obtains optical soliton solution to perturbed nonlinear Schrödinger's equation by modified simple equation method. There are four types of nonlinear fibers studied in this paper. They are Anti-cubic law, Quadratic-cubic law, Cubic-quintic-septic law and Triple-power law. Dark and singular soliton solutions are derived. Additional solutions such as singular periodic solutions also fall out of the integration scheme.

  12. Antibacterial and tribological behavior of self-assembled monolayer on optical lens

    NASA Astrophysics Data System (ADS)

    Horng, J. H.; Jeng, Y. R.; Wei, C. C.; Tasi, Y. T.

    2010-10-01

    This paper studies the effects of the antibacterial and anti-adhesion properties of self-assembled monolayers (SAMs) on optical parts. Therefore, the experiments in this study prepared several kinds of SAMs, including alkyl and biphenyl spacer chains with different surface terminal groups (-CH3,-COOH) and head groups (-SH). This study reports the growth of eight self-assembled monolayers on optical parts: OTS, ODS, OTS with antibacterial solution, ODS with antibacterial solution, and pure antibacterial solution, with bio-compatibility. Experimental results regarding the contact angle of five self-assembled monolayers show that ODS with antibacterial illustrated the maximum contact angle 103° 12 hours after reaction. The solutions of OTS, ODS with antibacterial, OTS with antibacterial, and pure anti-bacterial showed contact angles of 102°, 99°, 101°, and 59° respectively. These results indicate that the antibacterial solution has negligible effects on anti-adhesion property of optical lenses. The results of digital optical microscope system analysis show that in the antibacterial experiment of eight kinds of selfassembled monolayers, the OTSanti50% effect cultured for 24 hours achieved the best results, with a growth rate of 12%. The descending order of antibacterial effect is antibacterial 10%>ODS>OTS> antibacterial 50%>ODSanti50%>OTSanti10%>ODSanti10%. In summary, the surface treatment of optical lenses involving OTSanti 50% is the most capable of effectively increasing antifouling and antibacterial functions.

  13. Spatiotemporal optical dark X solitary waves.

    PubMed

    Baronio, Fabio; Chen, Shihua; Onorato, Miguel; Trillo, Stefano; Wabnitz, Stefan; Kodama, Yuji

    2016-12-01

    We introduce spatiotemporal optical dark X solitary waves of the (2+1)D hyperbolic nonlinear Schrödinger equation (NLSE), which rules wave propagation in a self-focusing and normally dispersive medium. These analytical solutions are derived by exploiting the connection between the NLSE and a well-known equation of hydrodynamics, namely the type II Kadomtsev-Petviashvili (KP-II) equation. As a result, families of shallow water X soliton solutions of the KP-II equation are mapped into optical dark X solitary wave solutions of the NLSE. Numerical simulations show that optical dark X solitary waves may propagate for long distances (tens of nonlinear lengths) before they eventually break up, owing to the modulation instability of the continuous wave background. This finding opens a novel path for the excitation and control of X solitary waves in nonlinear optics.

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patil, Vidya, E-mail: vidya.patil@ruparel.edu; Patki, Mugdha, E-mail: mugdha.patki@ruparel.edu

    Many nonlinear optical (NLO) crystals have been identified as potential candidates in optical and electro-optical devices. Use of NLO organic crystals is expected in photonic applications. Hence organic nonlinear optical materials have been intensely investigated due to their potentially high nonlinearities, and rapid response in electro-optic effect compared to inorganic NLO materials. There are many methods to grow organic crystals such as vapor growth method, melt growth method and solution growth method. Out of these methods, solution growth method is useful in providing constraint free crystal. Single crystals of Dopamine have been grown by evaporating the solvents from aqueous solution.more » Crystals obtained were of the size of orders of mm. The crystal structure of dopamine was determined using XRD technique. Images of crystals were obtained using FEG SEM Quanta Series under high vacuum and low KV.« less

  15. Propagation characteristics of optical fiber structures with arbitrary shape and index variation

    NASA Technical Reports Server (NTRS)

    Manshadi, F.

    1990-01-01

    The application of the scalar wave-fast Fourier transform (SW-FFT) technique to the computation of the propagation characteristics of some complex optical fiber structures is presented. The SW-FFT technique is based on the numerical solution of the scalar wave equation by a forward-marching fast Fourier transform method. This solution yields the spatial configuration of the fields as well as its modal characteristics in and around the guiding structure. The following are treated by the SW-FFT method: analysis of coupled optical fibers and computation of their odd and even modes and coupling length; the solution of tapered optical waveguides (transitions) and the study of the effect of the slope of the taper on mode conversion; and the analysis of branching optical fibers and demonstration of their mode-filtering and/or power-dividing properties.

  16. Early opacification and subsequent in vivo clearing of a silicone intraocular lens.

    PubMed

    Nikrooyan, Idean; Anderson, Justin E

    2011-09-01

    To report a case of early opacification and spontaneous in vivo clearing of a silicone intraocular lens (IOL). A 79-year-old women underwent uncomplicated cataract extraction and subsequent implantation of a +21.5 D AMO Z9002 (Abbott Medical Optics, Santa Ana, CA) silicone lens. On postoperative day 1, the patient presented with a translucent, milky white appearing, diffuse IOL opacification. On postoperative day 8, the IOL periphery had cleared, but a full thickness haze persisted in the central portion of the optic. By postoperative day 14, the IOL had cleared. To date, the lens has remained clear. One possible mechanism might be exposure to industrial chemicals; however, the manufacturer reports no other similar lens opacities from this manufacturing batch of IOLs. We recommend that surgeons who implant or have implanted an AMO Z9002 silicone IOL and observe similar findings follow the patient closely for resolution of the haze.

  17. Changes in morphology and optical properties of sclera and choroidal layers due to hyperosmotic agent.

    PubMed

    Zaman, Raiyan T; Rajaram, Narasimhan; Nichols, Brandon S; Rylander, Henry G; Wang, Tianyi; Tunnell, James W; Welch, Ashley J

    2011-07-01

    Light scattering in the normally white sclera prevents diagnostic imaging or delivery of a focused laser beam to a target in the underlying choroid layer. In this study, we examine optical clearing of the sclera and changes in blood flow resulting from the application of glycerol to the sclera of rabbits. Recovery dynamics are monitored after the application of saline. The speed of clearing for injection delivery is compared to the direct application of glycerol through an incision in the conjunctiva. Although, the same volume of glycerol was applied, the sclera cleared much faster (5 to 10 s) with the topical application of glycerol compared to the injection method (3 min). In addition, the direct topical application of glycerol spreads over a larger area in the sclera than the latter method. A diffuse optical spectroscopy system provided spectral analysis of the remitted light every two minutes during clearing and rehydration. Comparison of measurements to those obtained from phantoms with various absorption and scattering properties provided estimates of the absorption coefficient and reduced scattering coefficient of rabbit eye tissue.

  18. An underwater optical wireless communication network

    NASA Astrophysics Data System (ADS)

    Arnon, Shlomi

    2009-08-01

    The growing need for underwater observation and sub-sea monitoring systems has stimulated considerable interest in advancing the enabling technologies of underwater wireless communication and underwater sensor networks. This communication technology is expected to play an important role in investigating climate change, in monitoring biological, bio-geochemical, evolutionary and ecological changes in the sea, ocean and lake environments and in helping to control and maintain oil production facilities and harbors using unmanned underwater vehicles (UUVs), submarines, ships, buoys, and divers. However, the present technology of underwater acoustic communication cannot provide the high data rate required to investigate and monitor these environments and facilities. Optical wireless communication has been proposed as the best alternative to meet this challenge. We present models of three kinds of optical wireless communication links a) a line-of-sight link, b) a modulating retro-reflector link and c) a reflective link, all of which can provide the required data rate. We analyze the link performance based on these models. From the analysis, it is clear that as the water absorption increases, the communication performance decreases dramatically for the three link types. However, by using the scattered lighted it was possible to mitigate this decrease in some cases. We conclude from the analysis that a high data rate underwater optical wireless network is a feasible solution for emerging applications such as UUV to UUV links and networks of sensors, and extended ranges in these applications could be achieved by applying a multi-hop concept.

  19. Underwater optical wireless communication network

    NASA Astrophysics Data System (ADS)

    Arnon, Shlomi

    2010-01-01

    The growing need for underwater observation and subsea monitoring systems has stimulated considerable interest in advancing the enabling technologies of underwater wireless communication and underwater sensor networks. This communication technology is expected to play an important role in investigating climate change, in monitoring biological, biogeochemical, evolutionary, and ecological changes in the sea, ocean, and lake environments, and in helping to control and maintain oil production facilities and harbors using unmanned underwater vehicles (UUVs), submarines, ships, buoys, and divers. However, the present technology of underwater acoustic communication cannot provide the high data rate required to investigate and monitor these environments and facilities. Optical wireless communication has been proposed as the best alternative to meet this challenge. Models are presented for three kinds of optical wireless communication links: (a) a line-of-sight link, (b) a modulating retroreflector link, and (c) a reflective link, all of which can provide the required data rate. We analyze the link performance based on these models. From the analysis, it is clear that as the water absorption increases, the communication performance decreases dramatically for the three link types. However, by using the scattered light it was possible to mitigate this decrease in some cases. It is concluded from the analysis that a high-data-rate underwater optical wireless network is a feasible solution for emerging applications such as UUV-to-UUV links and networks of sensors, and extended ranges in these applications could be achieved by applying a multi-hop concept.

  20. Atmospheric Visibility Monitoring for planetary optical communications

    NASA Technical Reports Server (NTRS)

    Cowles, Kelly

    1991-01-01

    The Atmospheric Visibility Monitoring project endeavors to improve current atmospheric models and generate visibility statistics relevant to prospective earth-satellite optical communications systems. Three autonomous observatories are being used to measure atmospheric conditions on the basis of observed starlight; these data will yield clear-sky and transmission statistics for three sites with high clear-sky probabilities. Ground-based data will be compared with satellite imagery to determine the correlation between satellite data and ground-based observations.

  1. Optical design of the National Ignition Facility main laser and switchyard/target area beam transport systems

    NASA Astrophysics Data System (ADS)

    Miller, John L.; English, R. Edward, Jr.; Korniski, Ronald J.; Rodgers, J. Michael

    1999-07-01

    The optical design of the main laser and transport mirror sections of the National Ignition Facility are described. For the main laser the configuration, layout constraints, multiple beam arrangement, pinhole layout and beam paths, clear aperture budget, ray trace models, alignment constraints, lens designs, wavefront performance, and pupil aberrations are discussed. For the transport mirror system the layout, alignment controls and clear aperture budget are described.

  2. Liquid-crystal-based switchable polarizers for sensor protection.

    PubMed

    Wu, C S; Wu, S T

    1995-11-01

    Linear polarizers are generally employed in conjunction with advanced liquid-crystal filters for the protection of human eyes and optical sensors. For detection sensitivity under a no-threat condition to be maximized, the polarizer should remain in a clear state with a minimum insertion loss. When threats are present, it should be quickly switched to function as a linear polarizer with a high extinction ratio. Two types of switchable polarizer for sensor protection are demonstrated. The polarization conversion type exhibits a high optical efficiency in its clear state, a high extinction ratio in the linear polarizer state, and a fast switching speed, except that its field of view is limited to approximately ±10°. In contrast, an improved switchable dichroic polarizer functions effectively over a much wider field of view. However, its extinction ratio and optical efficiency in its clear state are lower than those of the polarization conversion type.

  3. Liquid-crystal-based switchable polarizers for sensor protection

    NASA Astrophysics Data System (ADS)

    Wu, Chiung-Sheng; Wu, Shin-Tson

    1995-11-01

    Linear polarizers are generally employed in conjunction with advanced liquid-crystal filters for the protection of human eyes and optical sensors. For detection sensitivity under a no-threat condition to be maximized, the polarizer should remain in a clear state with a minimum insertion loss. When threats are present, it should be quickly switched to function as a linear polarizer with a high extinction ratio. Two types of switchable polarizer for sensor protection are demonstrated. The polarization conversion type exhibits a high optical efficiency in its clear state, a high extinction ratio in the linear polarizer state, and a fast switching speed, except that its field of view is limited to approximately +/-10 deg In contrast, an improved switchable dichroic polarizer functions effectively over a much wider field of view. However, its extinction ratio and optical efficiency in its clear state are lower than those of the polarization conversion type.

  4. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: Characterisation of optically cleared paper by optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Fabritius, T.; Alarousu, E.; Prykäri, T.; Hast, J.; Myllylä, Risto

    2006-02-01

    Due to the highly light scattering nature of paper, the imaging depth of optical methods such as optical coherence tomography (OCT) is limited. In this work, we study the effect of refractive index matching on improving the imaging depth of OCT in paper. To this end, four different refractive index matching liquids (ethanol, 1-pentanol, glycerol and benzyl alcohol) with a refraction index between 1.359 and 1.538 were used in experiments. Low coherent light transmission was studied in commercial copy paper sheets, and the results indicate that benzyl alcohol offers the best improvement in imaging depth, while also being sufficiently stable for the intended purpose. Constructed cross-sectional images demonstrate visually that the imaging depth of OCT is considerably improved by optical clearing. Both surfaces of paper sheets can be detected along with information about the sheet's inner structure.

  5. Preparation of optically active (2RS,3SR)-2-amino-3-hydroxy-3-phenylpropanoic acid (threo-beta-phenylserine) via optical resolutions by replacing and preferential crystallization.

    PubMed

    Shiraiwa, Tadashi; Kawashima, Yuka; Ikaritani, Atsushi; Suganuma, Yumiko; Saijoh, Reiichi

    2006-08-01

    To obtain optically active threo-2-amino-3-hydroxy-3-phenylpropanoic acid (1) via optical resolutions by replacing and preferential crystallization, the racemic structure of (2RS,3SR)-1 hydrochloride [(2RS,3SR)-1.HCl] was examined based on the melting point, solubility, and infrared spectrum. (2RS,3SR)-1.HCl was indicated to exist as a conglomerate at room temperature, although it forms a racemic compound at the melting point. When, in optical resolution by replacing crystallization, L-phenylalanine methyl ester hydrochloride (L-2) was used as the optically active co-solute, (2R,3S)-1.HCl was preferentially crystallized from the supersaturated racemic solution; the use of D-2 as the co-solute afforded (2S,3R)-1.HCl with an optical purity of 95%. In addition, optical resolution by preferential crystallization was successfully achieved to give successively (2R,3S)- and (2S,3R)-1.HCl with optical purities of 90-92%. The (2R,3S)- and (2S,3R)-1.HCl purified by recrystallization from 1-propanol were treated with triethylamine in methanol to give optically pure (2R,3S)- and (2S,3R)-1.

  6. Population-based metaheuristic optimization in neutron optics and shielding design

    NASA Astrophysics Data System (ADS)

    DiJulio, D. D.; Björgvinsdóttir, H.; Zendler, C.; Bentley, P. M.

    2016-11-01

    Population-based metaheuristic algorithms are powerful tools in the design of neutron scattering instruments and the use of these types of algorithms for this purpose is becoming more and more commonplace. Today there exists a wide range of algorithms to choose from when designing an instrument and it is not always initially clear which may provide the best performance. Furthermore, due to the nature of these types of algorithms, the final solution found for a specific design scenario cannot always be guaranteed to be the global optimum. Therefore, to explore the potential benefits and differences between the varieties of these algorithms available, when applied to such design scenarios, we have carried out a detailed study of some commonly used algorithms. For this purpose, we have developed a new general optimization software package which combines a number of common metaheuristic algorithms within a single user interface and is designed specifically with neutronic calculations in mind. The algorithms included in the software are implementations of Particle-Swarm Optimization (PSO), Differential Evolution (DE), Artificial Bee Colony (ABC), and a Genetic Algorithm (GA). The software has been used to optimize the design of several problems in neutron optics and shielding, coupled with Monte-Carlo simulations, in order to evaluate the performance of the various algorithms. Generally, the performance of the algorithms depended on the specific scenarios, however it was found that DE provided the best average solutions in all scenarios investigated in this work.

  7. A wide variety of injection molding technologies is now applicable to small series and mass production

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bloß, P., E-mail: bloss@kuz-leipzig.de, E-mail: juettner@kuz-leipzig.de, E-mail: jacob@kuz-leipzig.de, E-mail: loeser@kuz-leipzig.de, E-mail: michaelis@kuz-leipzig.de, E-mail: krajewsky@kuz-leipzig.de; Jüttner, G., E-mail: bloss@kuz-leipzig.de, E-mail: juettner@kuz-leipzig.de, E-mail: jacob@kuz-leipzig.de, E-mail: loeser@kuz-leipzig.de, E-mail: michaelis@kuz-leipzig.de, E-mail: krajewsky@kuz-leipzig.de; Jacob, S., E-mail: bloss@kuz-leipzig.de, E-mail: juettner@kuz-leipzig.de, E-mail: jacob@kuz-leipzig.de, E-mail: loeser@kuz-leipzig.de, E-mail: michaelis@kuz-leipzig.de, E-mail: krajewsky@kuz-leipzig.de

    2014-05-15

    Micro plastic parts open new fields for application, e. g., to electronics, sensor technologies, optics, and medical engineering. Before micro parts can go to mass production, there is a strong need of having the possibility for testing different designs and materials including material combinations. Hence, flexible individual technical and technological solutions for processing are necessary. To manufacture high quality micro parts, a micro injection moulding machine named formicaPlast based on a two-step plunger injection technology was developed. Resulting from its design, the residence time and the accuracy problems for managing small shot volumes with reproducible high accuracy are uncompromisingly solved.more » Due to their simple geometry possessing smooth transitions and non adherent inner surfaces, the plunger units allow to process 'all' thermoplastics from polyolefines to high performance polymers, optical clear polymers, thermally sensitive bioresorbables, highly filled systems (the so-called powder injection molding PIM), and liquid silicon rubber (LSR, here with a special kit). The applied platform strategy in the 1K and 2K version allows integrating automation for assembling, handling and packaging. A perpendicular arrangement allows encapsulation of inserts, also partially, and integration of this machine into process chains. Considering a wide variety of different parts consisting of different materials, the high potential of the technology is demonstrated. Based on challenging industrial parts from electronic applications (2K micro MID and bump mat, where both are highly structured parts), the technological solutions are presented in more detail.« less

  8. Growth evolution and phase transition from chalcocite to digenite in nanocrystalline copper sulfide: Morphological, optical and electrical properties

    PubMed Central

    Quintana-Ramirez, Priscilla Vasthi; Santos-Cruz, José; Vega-González, Marina; Martínez-Alvarez, Omar; Castaño-Meneses, Víctor Manuel; Acosta-Torres, Laura Susana; de la Fuente-Hernández, Javier

    2014-01-01

    Summary Copper sulfide is a promising p-type inorganic semiconductor for optoelectronic devices such as solar cells, due its small band gap energy and its electrical properties. In this work nanocrystalline copper sulfide (CuxS), with two stoichiometric ratios (x = 2, 1.8) was obtained by one-pot synthesis at 220, 230, 240 and 260 °C in an organic solvent and amorphous CuxS was obtained in aqueous solution. Nanoparticle-like nucleation centers are formed at lower temperatures (220 °C), mixtures of morphologies (nanorods, nanodisks and nanoprisms) are seen at 230 and 240 °C, in which the nanodisks are predominant, while big hexagonal/prismatic crystals are obtained at 260 °C according to TEM results. A mixture of chalcocite and digenite phases was found at 230 and 240 °C, while a clear transition to a pure digenite phase was seen at 260 °C. The evolution of morphology and transition of phases is consistent to the electrical, optical, and morphological properties of the copper sulfide. In fact, digenite Cu1.8S is less resistive (346 Ω/sq) and has a lower energy band gap (1.6 eV) than chalcocite Cu2S (5.72 × 105 Ω/sq, 1.87 eV). Low resistivity was also obtained in CuxS synthesized in aqueous solution, despite its amorphous structure. All CuxS products could be promising for optoelectronic applications. PMID:25247136

  9. Growth evolution and phase transition from chalcocite to digenite in nanocrystalline copper sulfide: Morphological, optical and electrical properties.

    PubMed

    Quintana-Ramirez, Priscilla Vasthi; Arenas-Arrocena, Ma Concepción; Santos-Cruz, José; Vega-González, Marina; Martínez-Alvarez, Omar; Castaño-Meneses, Víctor Manuel; Acosta-Torres, Laura Susana; de la Fuente-Hernández, Javier

    2014-01-01

    Copper sulfide is a promising p-type inorganic semiconductor for optoelectronic devices such as solar cells, due its small band gap energy and its electrical properties. In this work nanocrystalline copper sulfide (Cu x S), with two stoichiometric ratios (x = 2, 1.8) was obtained by one-pot synthesis at 220, 230, 240 and 260 °C in an organic solvent and amorphous Cu x S was obtained in aqueous solution. Nanoparticle-like nucleation centers are formed at lower temperatures (220 °C), mixtures of morphologies (nanorods, nanodisks and nanoprisms) are seen at 230 and 240 °C, in which the nanodisks are predominant, while big hexagonal/prismatic crystals are obtained at 260 °C according to TEM results. A mixture of chalcocite and digenite phases was found at 230 and 240 °C, while a clear transition to a pure digenite phase was seen at 260 °C. The evolution of morphology and transition of phases is consistent to the electrical, optical, and morphological properties of the copper sulfide. In fact, digenite Cu1.8S is less resistive (346 Ω/sq) and has a lower energy band gap (1.6 eV) than chalcocite Cu2S (5.72 × 10(5) Ω/sq, 1.87 eV). Low resistivity was also obtained in Cu x S synthesized in aqueous solution, despite its amorphous structure. All Cu x S products could be promising for optoelectronic applications.

  10. Optical solitons, complexitons, Gaussian soliton and power series solutions of a generalized Hirota equation

    NASA Astrophysics Data System (ADS)

    Mao, Jin-Jin; Tian, Shou-Fu; Zou, Li; Zhang, Tian-Tian

    2018-05-01

    In this paper, we consider a generalized Hirota equation with a bounded potential, which can be used to describe the propagation properties of optical soliton solutions. By employing the hypothetical method and the sub-equation method, we construct the bright soliton, dark soliton, complexitons and Gaussian soliton solutions of the Hirota equation. Moreover, we explicitly derive the power series solutions with their convergence analysis. Finally, we provide the graphical analysis of such soliton solutions in order to better understand their dynamical behavior.

  11. Optical fiber nanoprobe preparation for near-field optical microscopy by chemical etching under surface tension and capillary action.

    PubMed

    Mondal, Samir K; Mitra, Anupam; Singh, Nahar; Sarkar, S N; Kapur, Pawan

    2009-10-26

    We propose a technique of chemical etching for fabrication of near perfect optical fiber nanoprobe (NNP). It uses photosensitive single mode optical fiber to etch in hydro fluoric (HF) acid solution. The difference in etching rate for cladding and photosensitive core in HF acid solution creates capillary ring along core-cladding boundary under a given condition. The capillary ring is filled with acid solution due to surface tension and capillary action. Finally it creates near perfect symmetric tip at the apex of the fiber as the height of the acid level in capillary ring decreases while width of the ring increases with continuous etching. Typical tip features are short taper length (approximately 4 microm), large cone angle (approximately 38 degrees ), and small probe tip dimension (<100 nm). A finite difference time domain (FDTD) analysis is also presented to compare near field optics of the NNP with conventional nanoprobe (CNP). The probe may be ideal for near field optical imaging and sensor applications.

  12. AIRBORNE INVESTIGATIONS OF CLEAR AIR TURBULENCE WITH OPTICAL RADAR.

    DTIC Science & Technology

    relevant meteorlogical data. The design of this equipment and the development of the flight programs was predicated on theoretical considerations of optical scattering from particulate matter. (Author)

  13. Highly specific and reversible fluoride sensor based on an organic semiconductor.

    PubMed

    Aboubakr, Hecham; Brisset, Hugues; Siri, Olivier; Raimundo, Jean-Manuel

    2013-10-15

    A novel sulfonamide-conjugated benzo-[2,1-b:3,4-b']bithiophene semiconductor has been designed and synthetized in order to develop a probe for specific detection of anions both in the homogeneous (solution) and heterogeneous phase. Its photophysical and electrochemical data were reported in this study. On the basis of the optical and NMR titrations analysis, the chelator was found to be highly selective for fluoride compared to others anions (Ka = 1.6 × 10(4) M(-1) in dimethyl sulfoxide (DMSO)). In addition, from an intricate sample, the novel chelator shows exceptional specificity toward fluoride and reveals a complete reversibility after addition of trifluoroacetic acid (TFA). Sensing films were obtained by electrochemical polymerization of the probe on an electrode surface, which clearly show effective detection of fluoride.

  14. Three-dimensional computation of laser cavity eigenmodes by the use of finite element analysis (FEA)

    NASA Astrophysics Data System (ADS)

    Altmann, Konrad; Pflaum, Christoph; Seider, David

    2004-06-01

    A new method for computing eigenmodes of a laser resonator by the use of finite element analysis (FEA) is presented. For this purpose, the scalar wave equation [Δ + k2]E(x,y,z) = 0 is transformed into a solvable 3D eigenvalue problem by separating out the propagation factor exp(-ikz) from the phasor amplitude E(x,y,z) of the time-harmonic electrical field. For standing wave resonators, the beam inside the cavity is represented by a two-wave ansatz. For cavities with parabolic optical elements the new approach has successfully been verified by the use of the Gaussian mode algorithm. For a DPSSL with a thermally lensing crystal inside the cavity the expected deviation between Gaussian approximation and numerical solution could be demonstrated clearly.

  15. Optimization of multicast optical networks with genetic algorithm

    NASA Astrophysics Data System (ADS)

    Lv, Bo; Mao, Xiangqiao; Zhang, Feng; Qin, Xi; Lu, Dan; Chen, Ming; Chen, Yong; Cao, Jihong; Jian, Shuisheng

    2007-11-01

    In this letter, aiming to obtain the best multicast performance of optical network in which the video conference information is carried by specified wavelength, we extend the solutions of matrix games with the network coding theory and devise a new method to solve the complex problems of multicast network switching. In addition, an experimental optical network has been testified with best switching strategies by employing the novel numerical solution designed with an effective way of genetic algorithm. The result shows that optimal solutions with genetic algorithm are accordance with the ones with the traditional fictitious play method.

  16. Research on optimal path planning algorithm of task-oriented optical remote sensing satellites

    NASA Astrophysics Data System (ADS)

    Liu, Yunhe; Xu, Shengli; Liu, Fengjing; Yuan, Jingpeng

    2015-08-01

    GEO task-oriented optical remote sensing satellite, is very suitable for long-term continuous monitoring and quick access to imaging. With the development of high resolution optical payload technology and satellite attitude control technology, GEO optical remote sensing satellites will become an important developing trend for aerospace remote sensing satellite in the near future. In the paper, we focused on GEO optical remote sensing satellite plane array stare imaging characteristics and real-time leading mission of earth observation mode, targeted on satisfying needs of the user with the minimum cost of maneuver, and put forward the optimal path planning algorithm centered on transformation from geographic coordinate space to Field of plane, and finally reduced the burden of the control system. In this algorithm, bounded irregular closed area on the ground would be transformed based on coordinate transformation relations in to the reference plane for field of the satellite payload, and then using the branch and bound method to search for feasible solutions, cutting off the non-feasible solution in the solution space based on pruning strategy; and finally trimming some suboptimal feasible solutions based on the optimization index until a feasible solution for the global optimum. Simulation and visualization presentation software testing results verified the feasibility and effectiveness of the strategy.

  17. Low cost fiber optic sensing of sugar solution

    NASA Astrophysics Data System (ADS)

    Muthuraju, M. E.; Patlolla, Anurag Reddy; Vadakkapattu Canthadai, Badrinath; Pachava, Vengalrao

    2015-03-01

    The demand for highly sensitive and reliable sensors to assess the refractive index of liquid get many applications in chemical and biomedical areas. Indeed, the physical parameters such as concentration, pressure and density, etc., can be found using the refractive index of liquid. In contrast to the conventional refractometer for measurement, optical fiber sensor has several advantages like remote sensing, small in size, low cost, immune to EMI etc., In this paper we have discussed determination of refractive index of sugar solution using optical fiber. An intensity modulated low cost plastic fiber optic refractive index sensor has been designed for the study. The sensor is based on principle of change in angle of reflected light caused by refractive index change of the medium surrounding the fiber. The experimental results obtained for the sugar solution of different refractive indices prove that the fiber optic sensor is cable of measuring the refractive indices as well as the concentrations.

  18. Optical wireless link between a nanoscale antenna and a transducing rectenna.

    PubMed

    Dasgupta, Arindam; Mennemanteuil, Marie-Maxime; Buret, Mickaël; Cazier, Nicolas; Colas-des-Francs, Gérard; Bouhelier, Alexandre

    2018-05-18

    Initiated as a cable-replacement solution, short-range wireless power transfer has rapidly become ubiquitous in the development of modern high-data throughput networking in centimeter to meter accessibility range. Wireless technology is now penetrating a higher level of system integration for chip-to-chip and on-chip radiofrequency interconnects. However, standard CMOS integrated millimeter-wave antennas have typical size commensurable with the operating wavelength, and are thus an unrealistic solution for downsizing transmitters and receivers to the micrometer and nanometer scale. Herein, we demonstrate a light-in and electrical signal-out, on-chip wireless near-infrared link between a 220 nm optical antenna and a sub-nanometer rectifying antenna converting the transmitted optical energy into direct electrical current. The co-integration of subwavelength optical functional devices with electronic transduction offers a disruptive solution to interface photons and electrons at the nanoscale for on-chip wireless optical interconnects.

  19. Monitoring of tissue modification with optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Zhang, Wei; Luo, Qingming; Yao, Lei; Cheng, Haiying; Zeng, Shaoqun

    2002-04-01

    An experimental monitoring of tissue modification of in vitro and in vivo rabbit dura mater with administration of osmotical agents, 40% glucose solution and glycerol, using optical coherence tomography was presented. The preliminary results of experimental study of influence of osmotical liquids (glucose solutions, glycerol) of rabbit dura mater were reported. The significant decreasing of the light from surface and increasing of the light from the deep of dura mater under action of osmotical solutions and the increasing of OCT imaging depth were demonstrated. Experiments showed that administration of osmolytes to dura mater allowed for effective and temporary control of its optical characteristics, which made dura mater more transparent, increased the ability of light penetrating the tissue, and consequently improved the optical imaging depth. It is a significant study, which can improve penetration of optical imaging of cerebral function and acquire more information of the deep brain tissue.

  20. Control of rabbit dura mater optical properties with osmotical liquids

    NASA Astrophysics Data System (ADS)

    Yao, Lei; Cheng, Haiying; Luo, Qingming; Zhang, Wei; Zeng, Shaoqun; Tuchin, Valery V.

    2002-04-01

    An experimental study of controlling the optical properties of in vitro and in vivo rabbit dura mater with administration of osmotical agents, 40% glucose solution and glycerol, using video camera and spectrometer was presented. The preliminary results of experimental study of influence of osmotical liquids (glucose solutions, glycerol) on transmittance (in vitro) and reflectance (in vivo) spectra of rabbit dura mater were reported. The significant decreasing of the reflectance and increasing of the transmittance of dura mater under action of osmotical solutions were demonstrated. Experiments showed that administration of osmolytes to dura mater allowed for effective and temporary control of its optical characteristics, which made dura mater more transparent, increased the ability of light penetrating the tissue, and consequently improved the optical imaging depth. It is a significant study, which can improve penetration of optical imaging of cerebral function and acquire more information of the deep brain tissue.

  1. Optically Clear and Resilient Free-Form µ-Optics 3D-Printed via Ultrafast Laser Lithography.

    PubMed

    Jonušauskas, Linas; Gailevičius, Darius; Mikoliūnaitė, Lina; Sakalauskas, Danas; Šakirzanovas, Simas; Juodkazis, Saulius; Malinauskas, Mangirdas

    2017-01-02

    We introduce optically clear and resilient free-form micro-optical components of pure (non-photosensitized) organic-inorganic SZ2080 material made by femtosecond 3D laser lithography (3DLL). This is advantageous for rapid printing of 3D micro-/nano-optics, including their integration directly onto optical fibers. A systematic study of the fabrication peculiarities and quality of resultant structures is performed. Comparison of microlens resiliency to continuous wave (CW) and femtosecond pulsed exposure is determined. Experimental results prove that pure SZ2080 is ∼20 fold more resistant to high irradiance as compared with standard lithographic material (SU8) and can sustain up to 1.91 GW/cm² intensity. 3DLL is a promising manufacturing approach for high-intensity micro-optics for emerging fields in astro-photonics and atto-second pulse generation. Additionally, pyrolysis is employed to homogeneously shrink structures up to 40% by removing organic SZ2080 constituents. This opens a promising route towards downscaling photonic lattices and the creation of mechanically robust glass-ceramic microstructures.

  2. Optically Clear and Resilient Free-Form μ-Optics 3D-Printed via Ultrafast Laser Lithography

    PubMed Central

    Jonušauskas, Linas; Gailevičius, Darius; Mikoliūnaitė, Lina; Sakalauskas, Danas; Šakirzanovas, Simas; Juodkazis, Saulius; Malinauskas, Mangirdas

    2017-01-01

    We introduce optically clear and resilient free-form micro-optical components of pure (non-photosensitized) organic-inorganic SZ2080 material made by femtosecond 3D laser lithography (3DLL). This is advantageous for rapid printing of 3D micro-/nano-optics, including their integration directly onto optical fibers. A systematic study of the fabrication peculiarities and quality of resultant structures is performed. Comparison of microlens resiliency to continuous wave (CW) and femtosecond pulsed exposure is determined. Experimental results prove that pure SZ2080 is ∼20 fold more resistant to high irradiance as compared with standard lithographic material (SU8) and can sustain up to 1.91 GW/cm2 intensity. 3DLL is a promising manufacturing approach for high-intensity micro-optics for emerging fields in astro-photonics and atto-second pulse generation. Additionally, pyrolysis is employed to homogeneously shrink structures up to 40% by removing organic SZ2080 constituents. This opens a promising route towards downscaling photonic lattices and the creation of mechanically robust glass-ceramic microstructures. PMID:28772389

  3. Fiber optic interconnect and optoelectronic packaging challenges for future generation avionics

    NASA Astrophysics Data System (ADS)

    Beranek, Mark W.

    2007-02-01

    Forecasting avionics industry fiber optic interconnect and optoelectronic packaging challenges that lie ahead first requires an assumption that military avionics architectures will evolve from today's centralized/unified concept based on gigabit laser, optical-to-electrical-to-optical switching and optical backplane technology, to a future federated/distributed or centralized/unified concept based on gigabit tunable laser, electro-optical switch and add-drop wavelength division multiplexing (WDM) technology. The requirement to incorporate avionics optical built-in test (BIT) in military avionics fiber optic systems is also assumed to be correct. Taking these assumptions further indicates that future avionics systems engineering will use WDM technology combined with photonic circuit integration and advanced packaging to form the technical basis of the next generation military avionics onboard local area network (LAN). Following this theme, fiber optic cable plants will evolve from today's multimode interconnect solution to a single mode interconnect solution that is highly installable, maintainable, reliable and supportable. Ultimately optical BIT for fiber optic fault detection and isolation will be incorporated as an integral part of a total WDM-based avionics LAN solution. Cost-efficient single mode active and passive photonic component integration and packaging integration is needed to enable reliable operation in the harsh military avionics application environment. Rugged multimode fiber-based transmitters and receivers (transceivers) with in-package optical BIT capability are also needed to enable fully BIT capable single-wavelength fiber optic links on both legacy and future aerospace platforms.

  4. Research and Development on Ultra-Lightweight Low-Loss Optical Fiber Communication Cable.

    DTIC Science & Technology

    FIBER OPTICS TRANSMISSION LINES, LIGHTWEIGHT), GLASS , FIBERS , ORGANIC COATINGS, POLYURETHANE RESINS, SOLUTIONS(GENERAL), POWDERS, ELECTROSTATICS...EXTRUSION, RUGGEDIZED EQUIPMENT, BROADBAND, OPTICAL COMMUNICATIONS, TACTICAL COMMUNICATIONS, FIBER OPTICS, LOSSES.

  5. Origin of poor doping efficiency in solution processed organic semiconductors.

    PubMed

    Jha, Ajay; Duan, Hong-Guang; Tiwari, Vandana; Thorwart, Michael; Miller, R J Dwayne

    2018-05-21

    Doping is an extremely important process where intentional insertion of impurities in semiconductors controls their electronic properties. In organic semiconductors, one of the convenient, but inefficient, ways of doping is the spin casting of a precursor mixture of components in solution, followed by solvent evaporation. Active control over this process holds the key to significant improvements over current poor doping efficiencies. Yet, an optimized control can only come from a detailed understanding of electronic interactions responsible for the low doping efficiencies. Here, we use two-dimensional nonlinear optical spectroscopy to examine these interactions in the course of the doping process by probing the solution mixture of doped organic semiconductors. A dopant accepts an electron from the semiconductor and the two ions form a duplex of interacting charges known as ion-pair complexes. Well-resolved off-diagonal peaks in the two-dimensional spectra clearly demonstrate the electronic connectivity among the ions in solution. This electronic interaction represents a well resolved electrostatically bound state, as opposed to a random distribution of ions. We developed a theoretical model to recover the experimental data, which reveals an unexpectedly strong electronic coupling of ∼250 cm -1 with an intermolecular distance of ∼4.5 Å between ions in solution, which is approximately the expected distance in processed films. The fact that this relationship persists from solution to the processed film gives direct evidence that Coulomb interactions are retained from the precursor solution to the processed films. This memory effect renders the charge carriers equally bound also in the film and, hence, results in poor doping efficiencies. This new insight will help pave the way towards rational tailoring of the electronic interactions to improve doping efficiencies in processed organic semiconductor thin films.

  6. Corrosion of orthodontic brackets in different spices: in vitro study.

    PubMed

    Chaturvedi, T P

    2014-01-01

    Moist environment in the mouth varies and causes variable amounts of corrosion of dental materials. This is of concern particularly when metallic implants, metallic fillings, orthodontic appliances are placed in the hostile electrolytic environment in the human mouth. Components of diet rich in salt and spices are important factors influencing the corrosion of metallic appliances placed in the oral cavity. To study in vitro corrosion of orthodontic metallic brackets immersed in solutions of salt and spices in artificial saliva. Orthodontic brackets were used for corrosion studies in artificial saliva, salt, and spices using electrochemical technique and surface analysis. Electrochemical studies using different parameters were done in solutions of artificial saliva containing salt and spices. Photomicrographs from the optical microscope were also obtained. RESULTS of corrosion studies have clearly demonstrated that certain spices such as turmeric and coriander are effective in reducing corrosion, whereas salt and red chili have been found to enhance it. Surface analysis of small pits present on the surface of the as-received bracket will initiate corrosion which leads to more pitting.

  7. Stochastic interactions of two Brownian hard spheres in the presence of depletants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Karzar-Jeddi, Mehdi; Fan, Tai-Hsi, E-mail: thfan@engr.uconn.edu; Tuinier, Remco

    2014-06-07

    A quantitative analysis is presented for the stochastic interactions of a pair of Brownian hard spheres in non-adsorbing polymer solutions. The hard spheres are hypothetically trapped by optical tweezers and allowed for random motion near the trapped positions. The investigation focuses on the long-time correlated Brownian motion. The mobility tensor altered by the polymer depletion effect is computed by the boundary integral method, and the corresponding random displacement is determined by the fluctuation-dissipation theorem. From our computations it follows that the presence of depletion layers around the hard spheres has a significant effect on the hydrodynamic interactions and particle dynamicsmore » as compared to pure solvent and uniform polymer solution cases. The probability distribution functions of random walks of the two interacting hard spheres that are trapped clearly shift due to the polymer depletion effect. The results show that the reduction of the viscosity in the depletion layers around the spheres and the entropic force due to the overlapping of depletion zones have a significant influence on the correlated Brownian interactions.« less

  8. Solvothermal synthesis of well-dispersed MF2 (M = Ca,Sr,Ba) nanocrystals and their optical properties

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaoming; Quan, Zewei; Yang, Jun; Yang, Piaoping; Lian, Hongzhou; Lin, Jun

    2008-02-01

    MF2 (M = Ca,Sr,Ba) nanocrystals (NCs) were synthesized via a solvothermal process in the presence of oleic acid and characterized by x-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared (FT-IR) spectra, UV/vis absorption spectra, photoluminescence (PL) excitation and emission spectra, and lifetimes, respectively. In the synthetic process, oleic acid as a surfactant played a crucial role in confining the growth and solubility of the MF2 NCs. The as-prepared CaF2, SrF2 and BaF2 NCs present morphologies of truncated octahedron, cube and sheet in a narrow distribution, respectively. Possible growth mechanisms were proposed to explain these results. The as-prepared NCs are highly crystalline and can be well dispersed in cyclohexane to form stable and clear colloidal solutions, which demonstrate strong emission bands centred at 400 nm in photoluminescence (PL) spectra compared with the cyclohexane solvent. The PL properties of the colloidal solutions of the as-prepared NCs can be ascribed to the trap states of surface defects.

  9. Soliton, rational, and periodic solutions for the infinite hierarchy of defocusing nonlinear Schrödinger equations.

    PubMed

    Ankiewicz, Adrian

    2016-07-01

    Analysis of short-pulse propagation in positive dispersion media, e.g., in optical fibers and in shallow water, requires assorted high-order derivative terms. We present an infinite-order "dark" hierarchy of equations, starting from the basic defocusing nonlinear Schrödinger equation. We present generalized soliton solutions, plane-wave solutions, and periodic solutions of all orders. We find that "even"-order equations in the set affect phase and "stretching factors" in the solutions, while "odd"-order equations affect the velocities. Hence odd-order equation solutions can be real functions, while even-order equation solutions are complex. There are various applications in optics and water waves.

  10. The Optics Institute of Southern California: organizing and implementing outreach effort

    NASA Astrophysics Data System (ADS)

    Silberman, Donn M.

    2003-10-01

    The Optics Institute of Southern California is organizing the local educational outreach effort. Working with local optics businesses, society chapters, science discovery centers, K-12, community college and university educators, and others from the global optics education and training community, the OISC is becoming a one-stop clearing house for a wide range of educational outreach activities.

  11. All-optical switching based on optical fibre long period gratings modified bacteriorhodopsin

    NASA Astrophysics Data System (ADS)

    Korposh, S.; James, S.; Partridge, M.; Sichka, M.; Tatam, R.

    2018-05-01

    All-optical switching using an optical fibre long-period gating (LPG) modified with bacteriorhodopsin (bR) is demonstrated. The switching process is based on the photo-induced RI change of bR, which in turn changes the phase matching conditions of the mode coupling by the LPG, leading to modulation of the propagating light. The effect was studied with an LPG immersed into a bR solution and with LPGs coated with the bR films, deposited onto the LPGs using the layer-by-layer electrostatic self-assembly (LbL) method. The dependence of the all-optical switching efficiency upon the concentration of the bR solution and on the grating period of the LPG was also studied. In addition, an in-fibre Mach-Zehnder interferometer (MZI) composed of a cascaded LPG pair separated by 30 mm and modified with bR was used to enhance the wavelength range of all-optical switching. The switching wavelength is determined by the grating period of the LPG. Switching efficiencies of 16% and 35% were observed when an LPG and an MZI were immersed into bR solutions, respectively. The switching time for devices coated with bR-films was within 1 s, 10 times faster than that observed for devices immersed into bR solution.

  12. Assessment of the Atmospheric Channel for Short (Ka-Band and Optical) Wavelengths

    NASA Technical Reports Server (NTRS)

    Piazzolla, Sabino

    2007-01-01

    Atmospheric turbulence under clear sky conditions is an impairment of the atmospheric channel that greatly affects propagation of optical signal in the troposphere. The turbulence manifests itself in a number of forms within the optical domain, from the twinkling of a star in a clear night, to resolution degradation in a large aperture telescope. Therefore, a body of analytical, numerical, and experimental tools has been developed in optics to study, simulate, and control effects of atmospheric turbulence on an optical signal. Incidentally, there has been an increasing demand for high data rate returns from NASA missions which has led to envision utilizing a carrier signal in the Ka-Band range. The impact of atmospheric turbulence effects must be evaluated and considered for this frequency domain. The purpose of this work is to show that when the turbulence strength from the optical case to the KaBand ease is properly scaled, one can apply the same mathematical simulation developed for optical to predict turbulence effects within the Ka-Band domain. As a demonstration of this principle, we present how the scintillations of a Ka-Band downlink return of a deep space signal was successfully reproduced through wave-optics simulation.

  13. Evaluation and quantification of reprocessing modification in single-use devices in interventional cardiology

    NASA Astrophysics Data System (ADS)

    Tessarolo, Francesco; Ferrari, Paolo; Silvia, Bortoluzzi; Motta, Antonella; Migliaresi, Claudio; Zennaro, Lucio; Rigo, Adelio; Guarrera, Giovanni Maria; Nollo, Giandomenico

    2004-11-01

    The increasing demand in interventional cardiology urges for reprocessing of single-use-labelled medical devices. To fulfil this aim, accurate and validated regeneration protocols are mandatory to guarantee sterility, functionality and safeness. The reprocessing protocol was realized by decontamination with chloro-donors, cleaning with enzymatic solutions and hydrogen peroxide gas plasma sterilization. Reprocessing effects on ablation and electrophysiology catheters were evaluated by assessing physical-chemical changes on surfaces and bulks, as a function of the reprocessing cycles number. Conventional optical microscopy and environmental scanning electron microscopy (ESEM) underlined the presence of micro-scratches on the polyurethane shaft surface. A clear correlation was found between surface damages and number of reprocessing cycles. Atomic force microscopy (AFM) confirmed the occurrence of physical-chemical etching of the polyurethane shaft caused by the hydrogen peroxide plasma sterilization, with increasing of nano-roughness at increasing number of the reprocessing cycles. UV-Vis spectra performed on the incubation solution of polymeric shaft sample, showed an absorbance increase at about 208 nm. This fact could be attributed to the water elution from the polymer of low molecular weight oligomers. The presence of hydrolysis products of the polymeric shaft after incubation demands both the characterization of the products released in the solution and the chemical characterization of the water exposed surface.

  14. Noninvasive measurement of glucose concentration on human fingertip by optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Chen, Tseng-Lin; Lo, Yu-Lung; Liao, Chia-Chi; Phan, Quoc-Hung

    2018-04-01

    A method is proposed for determining the glucose concentration on the human fingertip by extracting two optical parameters, namely the optical rotation angle and the depolarization index, using a Mueller optical coherence tomography technique and a genetic algorithm. The feasibility of the proposed method is demonstrated by measuring the optical rotation angle and depolarization index of aqueous glucose solutions with low and high scattering, respectively. It is shown that for both solutions, the optical rotation angle and depolarization index vary approximately linearly with the glucose concentration. As a result, the ability of the proposed method to obtain the glucose concentration by means of just two optical parameters is confirmed. The practical applicability of the proposed technique is demonstrated by measuring the optical rotation angle and depolarization index on the human fingertip of healthy volunteers under various glucose conditions.

  15. Introducing Optical Concepts in Electrical Engineering.

    ERIC Educational Resources Information Center

    Daneshvar, K.; Coleman, R.

    The expansion in the fields of optical engineering and optoelectronics has made it essential to introduce optical engineering concepts into undergraduate courses and curricula. Because of limits on the number of course requirements for the BS degree, it is not clear how these topics should be introduced without replacing some of the traditional…

  16. In-situ growth of AuNPs on WS2@U-bent optical fiber for evanescent wave absorption sensor

    NASA Astrophysics Data System (ADS)

    Zhang, Suzhen; Zhao, Yuefeng; Zhang, Chao; Jiang, Shouzhen; Yang, Cheng; Xiu, Xianwu; Li, Chonghui; Li, Zhen; Zhao, Xiaofei; Man, Baoyuan

    2018-05-01

    The sensitivity of the evanescent wave absorption sensor is always a hot topic which has been attracted researchers' discussion. It is still a challenge for developing the effective sensor to sensitively detect some biochemical molecules solution in a simple and low-cost way. In this paper, an evanescent wave absorption (EWA) sensor has been presented based on the U-bent multimode fiber coated with tungsten disulfide (WS2) film and in-situ growth of gold nanoparticles (AuNPs) for the detection of ethanol solution and sodium chloride (NaCl) solution. Benefitted from the effective light coupling produced between U-bent probe and AuNPs, we attained the optimal size of the AuNPs by changing the reaction time between WS2 and tetrachloroauric acid (HAuCl4). With the AuNPs/WS2@U-bent optical fiber, we discussed the behaviors of EWA sensor, such as sensitivity, reproducibility, fast response-recovery time and stability. The sensitivity (△A/△C) of the proposed AuNPs/WS2@U-bent optical fiber EWA sensor is 0.65 for the detection of the ethanol solution. Besides, the AuNPs/WS2@U-bent optical fiber EWA sensor exhibits high sensitivity in detection of the sodium chloride (NaCl), which can reach 1.5 when the proposed sensor was immersed into NaCl solution. Our work demonstrates that the U-bent optical fiber EWA sensor may have promising applications in testing the solution of concentration.

  17. Optical solitons to the resonance nonlinear Schrödinger equation by Sine-Gordon equation method

    NASA Astrophysics Data System (ADS)

    Inc, Mustafa; Aliyu, Aliyu Isa; Yusuf, Abdullahi; Baleanu, Dumitru

    2018-01-01

    In this paper, we examined the optical solitons to the resonant nonlinear Schrödinger equation (R-NLSE) which describes the propagation of solitons through optical fibers. Three types of nonlinear media fibers are studied. They are; quadratic-cubic law, Kerr law and parabolic law. Dark, bright, dark-bright or combined optical and singular soliton solutions are derived using the sine-Gordon equation method (SGEM). The constraint conditions that naturally fall out of the solution structure which guarantee the existence of these solitons are also reported.

  18. Tri-functional cannula for retinal endovascular surgery

    DOEpatents

    Weiss, Jonathan D [Albuquerque, NM

    2010-07-27

    A tri-functional cannula combines the functions of tissue Plasminogen Activator (tPA) solution delivery, illumination and venous pressure measurement. The cannula utilizes a tapered hollow-core optical fiber having an inlet for tPA solution, an attached fiber optic splitter configured to receive illumination light from an optical source such and a LED. A window in the cannula transmits the light to and from a central retinal vein. The return light is coupled to an optical detector to measure the pressure within the vein and determine whether an occlusion has been removed.

  19. 3D on-chip microscopy of optically cleared tissue

    NASA Astrophysics Data System (ADS)

    Zhang, Yibo; Shin, Yoonjung; Sung, Kevin; Yang, Sam; Chen, Harrison; Wang, Hongda; Teng, Da; Rivenson, Yair; Kulkarni, Rajan P.; Ozcan, Aydogan

    2018-02-01

    Traditional pathology relies on tissue biopsy, micro-sectioning, immunohistochemistry and microscopic imaging, which are relatively expensive and labor-intensive, and therefore are less accessible in resource-limited areas. Low-cost tissue clearing techniques, such as the simplified CLARITY method (SCM), are promising to potentially reduce the cost of disease diagnosis by providing 3D imaging and phenotyping of thicker tissue samples with simpler preparation steps. However, the mainstream imaging approach for cleared tissue, fluorescence microscopy, suffers from high-cost, photobleaching and signal fading. As an alternative approach to fluorescence, here we demonstrate 3D imaging of SCMcleared tissue using on-chip holography, which is based on pixel-super-resolution and multi-height phase recovery algorithms to digitally compute the sample's amplitude and phase images at various z-slices/depths through the sample. The tissue clearing procedures and the lens-free imaging system were jointly optimized to find the best illumination wavelength, tissue thickness, staining solution pH, and the number of hologram heights to maximize the imaged tissue volume, minimize the amount of acquired data, while maintaining a high contrast-to-noise ratio for the imaged cells. After this optimization, we achieved 3D imaging of a 200-μm thick cleared mouse brain tissue over a field-of-view of <20mm2 , and the resulting 3D z-stack agrees well with the images acquired with a scanning lens-based microscope (20× 0.75NA). Moreover, the lens-free microscope achieves an order-of-magnitude better data efficiency compared to its lens-based counterparts for volumetric imaging of samples. The presented low-cost and high-throughput lens-free tissue imaging technique enabled by CLARITY can be used in various biomedical applications in low-resource-settings.

  20. Controlled core removal from a D-shaped optical fiber.

    PubMed

    Markos, Douglas J; Ipson, Benjamin L; Smith, Kevin H; Schultz, Stephen M; Selfridge, Richard H; Monte, Thomas D; Dyott, Richard B; Miller, Gregory

    2003-12-20

    The partial removal of a section of the core from a continuous D-shaped optical fiber is presented. In the core removal process, selective chemical etching is used with hydrofluoric (HF) acid. A 25% HF acid solution removes the cladding material above the core, and a 5% HF acid solution removes the core. A red laser with a wavelength of 670 nm is transmitted through the optical fiber during the etching. The power transmitted through the optical fiber is correlated to the etch depth by scanning electron microscope imaging. The developed process provides a repeatable method to produce an optical fiber with a specific etch depth.

  1. Optical systolic solutions of linear algebraic equations

    NASA Technical Reports Server (NTRS)

    Neuman, C. P.; Casasent, D.

    1984-01-01

    The philosophy and data encoding possible in systolic array optical processor (SAOP) were reviewed. The multitude of linear algebraic operations achievable on this architecture is examined. These operations include such linear algebraic algorithms as: matrix-decomposition, direct and indirect solutions, implicit and explicit methods for partial differential equations, eigenvalue and eigenvector calculations, and singular value decomposition. This architecture can be utilized to realize general techniques for solving matrix linear and nonlinear algebraic equations, least mean square error solutions, FIR filters, and nested-loop algorithms for control engineering applications. The data flow and pipelining of operations, design of parallel algorithms and flexible architectures, application of these architectures to computationally intensive physical problems, error source modeling of optical processors, and matching of the computational needs of practical engineering problems to the capabilities of optical processors are emphasized.

  2. Applications of the ETEM for obtaining optical soliton solutions for the Lakshmanan-Porsezian-Daniel model

    NASA Astrophysics Data System (ADS)

    Manafian, Jalil; Foroutan, Mohammadreza; Guzali, Aref

    2017-11-01

    This paper examines the effectiveness of an integration scheme which is called the extended trial equation method (ETEM) for solving a well-known nonlinear equation of partial differential equations (PDEs). In this respect, the Lakshmanan-Porsezian-Daniel (LPD) equation with Kerr and power laws of nonlinearity which describes higher-order dispersion, full nonlinearity and spatiotemporal dispersion is considered, and as an achievement, a series of exact travelling-wave solutions for the aforementioned equation is formally extracted. Explicit new exact solutions are derived in different form such as dark solitons, bright solitons, solitary wave, periodic solitary wave, rational function, and elliptic function solutions of LPD equation. The movement of obtained solutions is shown graphically, which helps to understand the physical phenomena of this optical soliton equation. Many other such types of nonlinear equations arising in basic fabric of communications network technology and nonlinear optics can also be solved by this method.

  3. A Solution-Processed Ultrafast Optical Switch Based on a Nanostructured Epsilon-Near-Zero Medium.

    PubMed

    Guo, Qiangbing; Cui, Yudong; Yao, Yunhua; Ye, Yuting; Yang, Yue; Liu, Xueming; Zhang, Shian; Liu, Xiaofeng; Qiu, Jianrong; Hosono, Hideo

    2017-07-01

    All the optical properties of materials are derived from dielectric function. In spectral region where the dielectric permittivity approaches zero, known as epsilon-near-zero (ENZ) region, the propagating light within the material attains a very high phase velocity, and meanwhile the material exhibits strong optical nonlinearity. The interplay between the linear and nonlinear optical response in these materials thus offers unprecedented pathways for all-optical control and device design. Here the authors demonstrate ultrafast all-optical modulation based on a typical ENZ material of indium tin oxide (ITO) nanocrystals (NCs), accessed by a wet-chemistry route. In the ENZ region, the authors find that the optical response in these ITO NCs is associated with a strong nonlinear character, exhibiting sub-picosecond response time (corresponding to frequencies over 2 THz) and modulation depth up to ≈160%. This large optical nonlinearity benefits from the highly confined geometry in addition to the ENZ enhancement effect of the ITO NCs. Based on these ENZ NCs, the authors successfully demonstrate a fiber optical switch that allows switching of continuous laser wave into femtosecond laser pulses. Combined with facile processibility and tunable optical properties, these solution-processed ENZ NCs may offer a scalable and printable material solution for dynamic photonic and optoelectronic devices. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Optical clearing of vaginal tissues in cadavers

    NASA Astrophysics Data System (ADS)

    Chang, Chun-Hung; Hardy, Luke A.; Peters, Michael G.; Bastawros, Dina A.; Myers, Erinn M.; Kennelly, Michael J.; Fried, Nathaniel M.

    2018-02-01

    A nonsurgical laser procedure is being developed for treatment of female stress urinary incontinence (SUI). Previous studies in porcine vaginal tissues, ex vivo, as well as computer simulations, showed the feasibility of using near-infrared laser energy delivered through a transvaginal contact cooling probe to thermally remodel endopelvic fascia, while preserving the vaginal wall from thermal damage. This study explores optical properties of vaginal tissue in cadavers as an intermediate step towards future pre-clinical and clinical studies. Optical clearing of tissue using glycerol resulted in a 15-17% increase in optical transmission after 11 min at room temperature (and a calculated 32.5% increase at body temperature). Subsurface thermal lesions were created using power of 4.6 - 6.4 W, 5.2-mm spot, and 30 s irradiation time, resulting in partial preservation of vaginal wall to 0.8 - 1.1 mm depth.

  5. Optical clearing of human skin for the enhancement of optical imaging of proximal interphalangeal joints

    NASA Astrophysics Data System (ADS)

    Kolesnikova, Ekaterina A.; Kolesnikov, Aleksandr S.; Zabarylo, Urszula; Minet, Olaf; Genina, Elina A.; Bashkatov, Alexey N.; Tuchin, Valery V.

    2014-01-01

    We are proposing a new method for enhancement of optical imaging of proximal interphalangeal (PIP) joints in humans at skin using optical clearing technique. A set of illuminating laser diodes with the wavelengths 670, 820, and 904 nm were used as a light source. The laser diodes, monochromatic digital CCD camera and specific software allowed for detection of the finger joint image in a transillumination mode. The experiments were carried out in vivo with human fingers. Dehydrated glycerol and hand cream with urea (5%) were used as optical clearing agents (OCAs). The contrast of the obtained images was analyzed to determine the effect of the OCA. It was found that glycerol application to the human skin during 60 min caused the decrease of contrast in 1.4 folds for 670 nm and the increase of contrast in 1.5 and 1.7 folds for 820 nm and 904 nm, respectively. At the same time, the hand cream application to the human skin during 60 min caused the decrease of contrast in 1.1 folds for 670 nm and the increase of contrast in 1.3 and 1.1 folds for 820 nm and 904 nm, respectively. The results have shown that glycerol and the hand cream with 5% urea allow for obtaining of more distinct image of finger joint in the NIR. Obtained data can be used for development of optical diagnostic methods of rheumatoid arthritis.

  6. Characterization of a Hybrid Optical Microscopy/Laser Ablation Liquid Vortex Capture/Electrospray Ionization System for Mass Spectrometry Imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cahill, John F.; Kertesz, Vilmos; Van Berkel, Gary J.

    Herein, a commercial optical microscope, laser microdissection instrument was coupled with an electrospray ionization mass spectrometer via a low profile liquid vortex capture probe to yield a hybrid optical microscopy/mass spectrometry imaging system. The instrument has bright-field and fluorescence microscopy capabilities in addition to a highly focused UV laser beam that is utilized for laser ablation of samples. With this system, material laser ablated from a sample using the microscope was caught by a liquid vortex capture probe and transported in solution for analysis by electrospray ionization mass spectrometry. Both lane scanning and spot sampling mass spectral imaging modes weremore » used. The smallest area the system was able to ablate was ~0.544 μm × ~0.544 μm, achieved by oversampling of the smallest laser ablation spot size that could be obtained (~1.9 μm). With use of a model photoresist surface, known features as small as ~1.5 μm were resolved. The capabilities of the system with real world samples were demonstrated first with a blended polymer thin film containing poly(2-vinylpyridine) and poly(N-vinylcarbazole). Using spot sampling imaging, sub-micrometer sized features (0.62, 0.86, and 0.98 μm) visible by optical microscopy were clearly distinguished in the mass spectral images. A second real world example showed the imaging of trace amounts of cocaine in mouse brain thin tissue sections. Lastly, with use of a lane scanning mode with ~6 μm × ~6 μm data pixels, features in the tissue as small as 15 μm in size could be distinguished in both the mass spectral and optical images.« less

  7. Characterization of a Hybrid Optical Microscopy/Laser Ablation Liquid Vortex Capture/Electrospray Ionization System for Mass Spectrometry Imaging

    DOE PAGES

    Cahill, John F.; Kertesz, Vilmos; Van Berkel, Gary J.

    2015-10-22

    Herein, a commercial optical microscope, laser microdissection instrument was coupled with an electrospray ionization mass spectrometer via a low profile liquid vortex capture probe to yield a hybrid optical microscopy/mass spectrometry imaging system. The instrument has bright-field and fluorescence microscopy capabilities in addition to a highly focused UV laser beam that is utilized for laser ablation of samples. With this system, material laser ablated from a sample using the microscope was caught by a liquid vortex capture probe and transported in solution for analysis by electrospray ionization mass spectrometry. Both lane scanning and spot sampling mass spectral imaging modes weremore » used. The smallest area the system was able to ablate was ~0.544 μm × ~0.544 μm, achieved by oversampling of the smallest laser ablation spot size that could be obtained (~1.9 μm). With use of a model photoresist surface, known features as small as ~1.5 μm were resolved. The capabilities of the system with real world samples were demonstrated first with a blended polymer thin film containing poly(2-vinylpyridine) and poly(N-vinylcarbazole). Using spot sampling imaging, sub-micrometer sized features (0.62, 0.86, and 0.98 μm) visible by optical microscopy were clearly distinguished in the mass spectral images. A second real world example showed the imaging of trace amounts of cocaine in mouse brain thin tissue sections. Lastly, with use of a lane scanning mode with ~6 μm × ~6 μm data pixels, features in the tissue as small as 15 μm in size could be distinguished in both the mass spectral and optical images.« less

  8. Optical limiting properties of optically active phthalocyanine derivatives

    NASA Astrophysics Data System (ADS)

    Wang, Peng; Zhang, Shuang; Wu, Peiji; Ye, Cheng; Liu, Hongwei; Xi, Fu

    2001-06-01

    The optical limiting properties of four optically active phthalocyanine derivatives in chloroform solutions and epoxy resin thin plates were measured at 532 nm with 10 ns pulses. The excited state absorption cross-section σex and refractive-index cross-section σr were determined with the Z-scan technique. These chromophores possess larger σex than the ground state absorption cross-section σ0, indicating that they are the potential materials for reverse saturable absorption (RSA). The negative σr values of these chromophores add to the thermal contribution, producing a larger defocusing effect, which may be helpful in further enhancing their optical limiting performance. The optical limiting responses of the thin plate samples are stronger than those of the chloroform solutions.

  9. Photodeposition of Thin Polydiacetylene Films from Solution that Exhibit Large Third-Order Optical Nonlinearities

    NASA Technical Reports Server (NTRS)

    Paley, M. S.; Frazier, D. O.; Abdeldayem, H.; McManus, S. P.

    1994-01-01

    One promising class of organic compounds for applications in the field of nonlinear optics (NLO) are polydiacetylenes, which are of interest because they are highly conjugated polymers capable of exhibiting very large optical nonlinearities with fast response times. During the course of crystal growth studies in anticipation of a space experiment, we discovered a novel, simple method for the formation of polydiacetylene thin films by photodeposition from monomer solutions onto quartz or glass substrates. Characterization of these PDAMNA films is not trivial; they are not soluble in common organic solvents, which makes the standard solution-based methods of polymer analysis useless.

  10. Development Of Fiber Optics For Passenger Car Applications

    NASA Astrophysics Data System (ADS)

    Steele, R. E.; Schmitt, H. J.

    1987-12-01

    The benefits of fiber optics for telecommunications and Local Area Networks (LANs) are well documented. The benefits to passenger car applications are not as clearly defined. This paper examines the differences between Telecommunications, LAN, and automotive point to point and network applications. Current production automotive applications of optics and fiber optics, automotive data communications trends, and both functional and non-functional requirements and constraints will be described.

  11. Base-Level Management of Laser Radiation Protection Program

    DTIC Science & Technology

    1992-02-01

    safety eyewear . special considerations for medical lasers and optical fibers, and summary evaluations of common Air Force laser systems... optical density of 2. Laser safety eyewear should have the optical density clearly marked for ail wavelengths for which the eyewear provides protection. c...density of protective eyewear . The optical density required for laser safety eyewear is dependent on the irradiance or radiant exposure-of the

  12. The effect of ionic Co presence on the structural, optical and photocatalytic properties of modified cobalt-titanate nanotubes.

    PubMed

    Barrocas, B; Silvestre, A J; Rolo, A G; Monteiro, O C

    2016-07-21

    With the aim of producing materials with enhanced optical and photocatalytic properties, titanate nanotubes (TNTs) modified by cobalt doping (Co-TNT) and by Na(+)→ Co ion-exchange (TNT/Co) were successfully prepared by a hydrothermal method. The influence of the doping level and of the cobalt position in the TNT crystalline structure was studied. Although no perceptible influence of the cobalt ion position on the morphology of the prepared titanate nanotubes was observed, the optical behaviour of the cobalt modified samples is clearly dependent on the cobalt ions either substituting the Ti(4+) ions in the TiO6 octahedra building blocks of the TNT structure (doped samples) or replacing the Na(+) ions between the TiO6 interlayers (ion-exchange samples). The catalytic ability of these materials on pollutant photodegradation was investigated. First, the evaluation of hydroxyl radical formation using the terephthalic acid as a probe was performed. Afterwards, phenol, naphthol yellow S and brilliant green were used as model pollutants. Anticipating real world situations, photocatalytic experiments were performed using solutions combining these pollutants. The results show that the Co modified TNT materials (Co-TNT and TNT/Co) are good catalysts, the photocatalytic performance being dependent on the Co/Ti ratio and on the structural metal location. The Co(1%)-TNT doped sample was the best photocatalyst for all the degradation processes studied.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dodson-Robinson, Sarah E.; Salyk, Colette, E-mail: sdr@astro.as.utexas.edu

    Although there has yet been no undisputed discovery of a still-forming planet embedded in a gaseous protoplanetary disk, the cleared inner holes of transitional disks may be signposts of young planets. Here, we show that the subset of accreting transitional disks with wide, optically thin inner holes of 15 AU or more can only be sculpted by multiple planets orbiting inside each hole. Multiplanet systems provide two key ingredients for explaining the origins of transitional disks. First, multiple planets can clear wide inner holes where single planets open only narrow gaps. Second, the confined, non-axisymmetric accretion flows produced by multiplemore » planets provide a way for an arbitrary amount of mass transfer to occur through an apparently optically thin hole without overproducing infrared excess flux. Rather than assuming that the gas and dust in the hole are evenly and axisymmetrically distributed, one can construct an inner hole with apparently optically thin infrared fluxes by covering a macroscopic fraction of the hole's surface area with locally optically thick tidal tails. We also establish that other clearing mechanisms, such as photoevaporation, cannot explain our subset of accreting transitional disks with wide holes. Transitional disks are therefore high-value targets for observational searches for young planetary systems.« less

  14. Magneto-optical contrast in liquid-state optically detected NMR spectroscopy

    PubMed Central

    Pagliero, Daniela; Meriles, Carlos A.

    2011-01-01

    We use optical Faraday rotation (OFR) to probe nuclear spins in real time at high-magnetic field in a range of diamagnetic sample fluids. Comparison of OFR-detected NMR spectra reveals a correlation between the relative signal amplitude and the fluid Verdet constant, which we interpret as a manifestation of the variable detuning between the probe beam and the sample optical transitions. The analysis of chemical-shift-resolved, optically detected spectra allows us to set constraints on the relative amplitudes of hyperfine coupling constants, both for protons at chemically distinct sites and other lower-gyromagnetic-ratio nuclei including carbon, fluorine, and phosphorous. By considering a model binary mixture we observe a complex dependence of the optical response on the relative concentration, suggesting that the present approach is sensitive to the solvent-solute dynamics in ways complementary to those known in inductive NMR. Extension of these experiments may find application in solvent suppression protocols, sensitivity-enhanced NMR of metalloproteins in solution, the investigation of solvent-solute interactions, or the characterization of molecular orbitals in diamagnetic systems. PMID:22100736

  15. 77 FR 34448 - Self-Regulatory Organizations; National Stock Exchange, Inc.; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Rules and Procedures in Order To Approve Apex Clearing Corporation, f/k/a Ridge Clearing and Outsourcing... Clearing Corporation, f/k/a Ridge Clearing and Outsourcing Solutions, Inc. (``Apex Clearing'') as an NSX... regarding the application process for ETP Holders in order to immediately approve Apex Clearing as an NSX...

  16. Optics education in an optometric setting

    NASA Astrophysics Data System (ADS)

    Putnam, Nicole M.

    2017-08-01

    The first year optics curriculum at the Arizona College of Optometry aims to provide students with an understanding of geometrical, physical, and visual optics principals that will be the foundation of their clinical understanding of the optics of the eye and its correction in advanced courses such as ophthalmic optics and contact lenses. Although the optics of the eye are a fantastic model to use in optics education, the clinical applications may not become apparent until later in the course of study. Successful strategies are needed to engage students and facilitate the understanding of optical principals and the growth of process skills including problem solving, analysis, and critical thinking that will help in their future as health care providers. These include the implementation of ophthalmic applications as early as possible, encouragement of group work including open office hours, and the use of video problem set solutions to supplement traditional static solutions.

  17. eLISA Telescope In-field Pointing and Scattered Light Study

    NASA Astrophysics Data System (ADS)

    Livas, J.; Sankar, S.; West, G.; Seals, L.; Howard, J.; Fitzsimons, E.

    2017-05-01

    The orbital motion of the three spacecraft that make up the eLISA Observatory constellation causes long-arm line of sight variations of approximately ± one degree over the course of a year. The baseline solution is to package the telescope, the optical bench, and the gravitational reference sensor (GRS) into an optical assembly at each end of the measurement arm, and then to articulate the assembly. An optical phase reference is exchanged between the moving optical benches with a single mode optical fiber (“backlink” fiber). An alternative solution, referred to as in-field pointing, embeds a steering mirror into the optical design, fixing the optical benches and eliminating the backlink fiber, but requiring the additional complication of a two-stage optical design for the telescope. We examine the impact of an in-field pointing design on the scattered light performance.

  18. Sedimentation Velocity Analysis of Large Oligomeric Chromatin Complexes Using Interference Detection.

    PubMed

    Rogge, Ryan A; Hansen, Jeffrey C

    2015-01-01

    Sedimentation velocity experiments measure the transport of molecules in solution under centrifugal force. Here, we describe a method for monitoring the sedimentation of very large biological molecular assemblies using the interference optical systems of the analytical ultracentrifuge. The mass, partial-specific volume, and shape of macromolecules in solution affect their sedimentation rates as reflected in the sedimentation coefficient. The sedimentation coefficient is obtained by measuring the solute concentration as a function of radial distance during centrifugation. Monitoring the concentration can be accomplished using interference optics, absorbance optics, or the fluorescence detection system, each with inherent advantages. The interference optical system captures data much faster than these other optical systems, allowing for sedimentation velocity analysis of extremely large macromolecular complexes that sediment rapidly at very low rotor speeds. Supramolecular oligomeric complexes produced by self-association of 12-mer chromatin fibers are used to illustrate the advantages of the interference optics. Using interference optics, we show that chromatin fibers self-associate at physiological divalent salt concentrations to form structures that sediment between 10,000 and 350,000S. The method for characterizing chromatin oligomers described in this chapter will be generally useful for characterization of any biological structures that are too large to be studied by the absorbance optical system. © 2015 Elsevier Inc. All rights reserved.

  19. Optical soliton solutions, periodic wave solutions and complexitons of the cubic Schrödinger equation with a bounded potential

    NASA Astrophysics Data System (ADS)

    Yan, Xue-Wei; Tian, Shou-Fu; Dong, Min-Jie; Zou, Li

    2018-01-01

    In this paper, we consider the cubic Schrödinger equation with a bounded potential, which describes the propagation properties of optical soliton solutions. By employing an ansatz method, we precisely derive the bright and dark soliton solutions of the equation. Moreover, we obtain three classes of analytic periodic wave solutions expressed in terms of the Jacobi's elliptic functions including cn ,sn and dn functions. Finally, by using a tanh function method, its complexitons solutions are derived in a very natural way. It is hoped that our results can enrich the nonlinear dynamical behaviors of the cubic Schrödinger equation with a bounded potential.

  20. Color correction strategies in optical design

    NASA Astrophysics Data System (ADS)

    Pfisterer, Richard N.; Vorndran, Shelby D.

    2014-12-01

    An overview of color correction strategies is presented. Starting with basic first-order aberration theory, we identify known color corrected solutions for doublets and triplets. Reviewing the modern approaches of Robb-Mercado, Rayces-Aguilar, and C. de Albuquerque et al, we find that they confirm the existence of glass combinations for doublets and triplets that yield color corrected solutions that we already know exist. Finally we explore the use of the y, ӯ diagram in conjunction with aberration theory to identify the solution space of glasses capable of leading to color corrected solutions in arbitrary optical systems.

  1. Optical clearing of the dura mater using glycerol: a reversible process to aid the post-mortem investigation of infant head injury.

    PubMed

    Cheshire, Emma C; Malcomson, Roger D G; Joseph, Shiju; Biggs, Mike J B; Adlam, David; Rutty, Guy N

    2015-09-01

    In cases of suspected abusive head trauma, a thorough and systematic study of the cranium and its contents is essential, preferably using the best available methods for observing the brain and its coverings. Building upon recent developments in skull bone removal techniques in infant autopsies, we have assessed the use of two optical clearing agents (OCAs), glycerol and mannitol, on pediatric dura mater in an attempt to increase the transparency of this tissue and thereby enhance the post-mortem assessment of infant head injuries, particularly subdural hematomas. Extracorporeal testing revealed glycerol to be the more effective OCA. Therefore, in situ investigations were commenced using glycerol during 33 pediatric post-mortem examinations. An increase in the transparency of the dura was observed in 32 of the 33 cases, within 1 min of application of the OCA. In a 2 year old with cerebral palsy, only partial optical clearance of the dura was seen, most likely due to a significantly atrophic brain, prominent gelatinous leptomeninges, and abnormally thickened dura. This technique allowed for detection of minimal amounts of subdural bleeding over the convexities, before dissection of the dura, avoiding post-mortem blood spillage from artifactually disrupted bridging veins. Optical clearing of the dura aided in the evaluation of patterns of subdural hemorrhage in three cases of non-accidental head injury, three cases of peri-natal head injury and one case of overlaying, apparently resulting in minor crush injury to the head. We have demonstrated that glycerol is an effective and easy-to-use OCA to effect the readily reversible optical clearing of human infant calvarial dura at autopsy.

  2. Label-free volumetric optical imaging of intact murine brains

    NASA Astrophysics Data System (ADS)

    Ren, Jian; Choi, Heejin; Chung, Kwanghun; Bouma, Brett E.

    2017-04-01

    A central effort of today’s neuroscience is to study the brain’s ’wiring diagram’. The nervous system is believed to be a network of neurons interacting with each other through synaptic connection between axons and dendrites, therefore the neuronal connectivity map not only depicts the underlying anatomy, but also has important behavioral implications. Different approaches have been utilized to decipher neuronal circuits, including electron microscopy (EM) and light microscopy (LM). However, these approaches typically demand extensive sectioning and reconstruction for a brain sample. Recently, tissue clearing methods have enabled the investigation of a fully assembled biological system with greatly improved light penetration. Yet, most of these implementations, still require either genetic or exogenous contrast labeling for light microscopy. Here we demonstrate a high-speed approach, termed as Clearing Assisted Scattering Tomography (CAST), where intact brains can be imaged at optical resolution without labeling by leveraging tissue clearing and the scattering contrast of optical frequency domain imaging (OFDI).

  3. Penetration kinetics of dimethyl sulphoxide and glycerol in dynamic optical clearing of porcine skin tissue in vitro studied by Fourier transform infrared spectroscopic imaging.

    PubMed

    Jiang, Jingying; Boese, Matthias; Turner, Paul; Wang, Ruikang K

    2008-01-01

    By use of a Fourier transform infrared (FTIR) spectroscopic imaging technique, we examine the dynamic optical clearing processes occurring in hyperosmotically biocompatible agents penetrating into skin tissue in vitro. The sequential collection of images in a time series provides an opportunity to assess penetration kinetics of dimethyl sulphoxide (DMSO) and glycerol beneath the surface of skin tissue over time. From 2-D IR spectroscopic images and 3-D false color diagrams, we show that glycerol takes at least 30 min to finally penetrate the layer of epidermis, while DMSO can be detected in epidermis after only 4 min of being topically applied over stratum corneum sides of porcine skin. The results demonstrate the potential of a FTIR spectroscopic imaging technique as an analytical tool for the study of dynamic optical clearing effects when the bio-tissue is impregnated by hyperosmotically biocompatible agents such as glycerol and DMSO.

  4. Advanced Secure Optical Image Processing for Communications

    NASA Astrophysics Data System (ADS)

    Al Falou, Ayman

    2018-04-01

    New image processing tools and data-processing network systems have considerably increased the volume of transmitted information such as 2D and 3D images with high resolution. Thus, more complex networks and long processing times become necessary, and high image quality and transmission speeds are requested for an increasing number of applications. To satisfy these two requests, several either numerical or optical solutions were offered separately. This book explores both alternatives and describes research works that are converging towards optical/numerical hybrid solutions for high volume signal and image processing and transmission. Without being limited to hybrid approaches, the latter are particularly investigated in this book in the purpose of combining the advantages of both techniques. Additionally, pure numerical or optical solutions are also considered since they emphasize the advantages of one of the two approaches separately.

  5. Managing Radiation Therapy Side Effects: What to Do When You Have Loose Stools (Diarrhea)

    MedlinePlus

    ... Drink lots of clear liquids, such as water, ginger ale, and clear soup. n Most people who ... beef Drinks (clear liquids) • Clear soda, such as ginger ale • Cranberry or grape juice • Oral rehydration solution ...

  6. New Treatments for Nonarteritic Anterior Ischemic Optic Neuropathy.

    PubMed

    Foroozan, Rod

    2017-02-01

    Despite increasing knowledge about the risk factors and clinical findings of nonarteritic anterior ischemic optic neuropathy (NAION), the treatment of this optic neuropathy has remained limited and without clear evidence-based benefit. Historical treatments of NAION are reviewed, beginning with the Ischemic Optic Neuropathy Decompression Trial. More recent treatments are placed within the historical context and illustrate the need for evidence-based therapy for ischemic optic neuropathy. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Multiscale solutions of radiative heat transfer by the discrete unified gas kinetic scheme

    NASA Astrophysics Data System (ADS)

    Luo, Xiao-Ping; Wang, Cun-Hai; Zhang, Yong; Yi, Hong-Liang; Tan, He-Ping

    2018-06-01

    The radiative transfer equation (RTE) has two asymptotic regimes characterized by the optical thickness, namely, optically thin and optically thick regimes. In the optically thin regime, a ballistic or kinetic transport is dominant. In the optically thick regime, energy transport is totally dominated by multiple collisions between photons; that is, the photons propagate by means of diffusion. To obtain convergent solutions to the RTE, conventional numerical schemes have a strong dependence on the number of spatial grids, which leads to a serious computational inefficiency in the regime where the diffusion is predominant. In this work, a discrete unified gas kinetic scheme (DUGKS) is developed to predict radiative heat transfer in participating media. Numerical performances of the DUGKS are compared in detail with conventional methods through three cases including one-dimensional transient radiative heat transfer, two-dimensional steady radiative heat transfer, and three-dimensional multiscale radiative heat transfer. Due to the asymptotic preserving property, the present method with relatively coarse grids gives accurate and reliable numerical solutions for large, small, and in-between values of optical thickness, and, especially in the optically thick regime, the DUGKS demonstrates a pronounced computational efficiency advantage over the conventional numerical models. In addition, the DUGKS has a promising potential in the study of multiscale radiative heat transfer inside the participating medium with a transition from optically thin to optically thick regimes.

  8. A Small U-Shaped Bending-Induced Interference Optical Fiber Sensor for the Measurement of Glucose Solutions.

    PubMed

    Fang, Yu-Lin; Wang, Chen-Tung; Chiang, Chia-Chin

    2016-09-09

    The study proposes a small U-shaped bending-induced interference optical fiber sensor; this novel sensor is a probe-type sensor manufactured using a mechanical device, a heat source, optical fiber and a packaging module. This probe-type sensor overcomes the shortcomings of conventional optical fibers, including being difficult to repair and a tendency to be influenced by external forces. We manufactured three types of sensors with different curvature radiuses. Specifically, sensors with three radiuses (1.5 mm, 2.0 mm, and 3.0 mm) were used to measure common water and glucose solutions with concentrations of between 6% and 30% (the interval between concentrations was 4%). The results show that the maximal sensitivity was 0.85 dB/% and that the linearly-dependent coefficient was 0.925. The results further show that not only can the small U-shaped bending-induced interference optical fiber sensor achieve high sensitivity in the measurement of glucose solutions, but that it can also achieve great stability and repeatability.

  9. Ternary liquid scintillator for optical fiber applications

    DOEpatents

    Franks, Larry A.; Lutz, Stephen S.

    1982-01-01

    A multicomponent liquid scintillator solution for use as a radiation-to-light converter in conjunction with a fiber optic transmission system. The scintillator includes a quantity of 5-amino-9-diethylaminobenz (a) phenoxazonium nitrate (Nile Blue Nitrate) as a solute in a fluor solvent such as benzyl alcohol. The use of PPD as an additional solute is also disclosed. The system is controllable by addition of a suitable quenching agent, such as phenol.

  10. Controllable optical rogue waves via nonlinearity management.

    PubMed

    Yang, Zhengping; Zhong, Wei-Ping; Belić, Milivoj; Zhang, Yiqi

    2018-03-19

    Using a similarity transformation, we obtain analytical solutions to a class of nonlinear Schrödinger (NLS) equations with variable coefficients in inhomogeneous Kerr media, which are related to the optical rogue waves of the standard NLS equation. We discuss the dynamics of such optical rogue waves via nonlinearity management, i.e., by selecting the appropriate nonlinearity coefficients and integration constants, and presenting the solutions. In addition, we investigate higher-order rogue waves by suitably adjusting the nonlinearity coefficient and the rogue wave parameters, which could help in realizing complex but controllable optical rogue waves in properly engineered fibers and other photonic materials.

  11. Investigation of Chemical Durability Mechanisms and Structure of Fluoride Glasses.

    DTIC Science & Technology

    1988-03-01

    coatings on fluoride glasses , it is possible to state the following conclusions: ()Coatings are necessary for both bulk and fiber optics to avoid major...interest for fiber optics applications.’ The chemicalSp . b g rdurability behavior of fluoride glasses not containing zirconium will be reported in later... fiber optics glass containing the base ZBL composition with where X = ppm in solution. V = solution volume (mL), S = additives of Al, Li, and Pb (Fig. 2

  12. Visual performance assessment through clear and sunscreen-treated windows.

    DOT National Transportation Integrated Search

    1978-09-01

    Reflective sunscreen filters are frequently bonded to vehicle windows to reduce interior heat and brightness. The present study was conducted to investigate the optical properties of and visual preformance through clear and sunscreen-treated glass pa...

  13. Chitin Nanofibers Extracted from Crab Shells in Broadband Visible Antireflection Coatings with Controlling Layer-by-Layer Deposition and the Application for Durable Antifog Surfaces.

    PubMed

    Manabe, Kengo; Tanaka, Chie; Moriyama, Yukari; Tenjimbayashi, Mizuki; Nakamura, Chiaki; Tokura, Yuki; Matsubayashi, Takeshi; Kyung, Kyu-Hong; Shiratori, Seimei

    2016-11-23

    Reflection from various surfaces of many optical systems, such as photovoltaics and displays, is a critical issue for their performance, and antireflection coatings play a pivotal role in a wide variety of optical technologies, reducing light reflectance loss and hence maximizing light transmission. With the current movement toward optically transparent polymeric media and coatings for antireflection technology, the need for economical and environmentally friendly materials and methods without dependence on shape or size has clearly been apparent. Herein, we demonstrate novel antireflection coatings composed of chitin nanofibers (CHINFs), extracted from crab shell as a biomass material through an aqueous-based layer-by-layer self-assembly process to control the porosity. Increasing the number of air spaces inside the membrane led low refractive index, and precise control of refractive index derived from the stacking of the CHINFs achieved the highest transmittance with investigating the surface structure and the refractive index depending on the solution pH. At a wavelength of 550 nm, the transmittance of the coatings was 96.4%, which was 4.8% higher than that of a glass substrate, and their refractive index was 1.30. Further critical properties of the films were the durability and the antifogging performance derived from the mechanical stability and hydrophilicity of CHINFs, respectively. The present study may contribute to a development of systematically designed nanofibrous films which are suitable for optical applications operating at a broadband visible wavelength with durability and antifog surfaces.

  14. Investigations on photoelectrochemical performance of boron doped ZnO nanorods synthesized by facile hydrothermal technique

    NASA Astrophysics Data System (ADS)

    Sharma, Akash; Chakraborty, Mohua; Thangavel, R.

    2018-05-01

    Undoped and 10% Boron (B)-doped Zinc Oxide nanorods (ZnO NRs) on Tin doped Indium Oxide (ITO) coated glass substrates were synthesized using facile sol-gel, spin coating and hydrothermal method. The impact of adding Boron on the structural, optical properties, surface morphology and photoelectrochemical (PEC) performances of the ZnO NRs have been investigated. The XRD pattern confirmed the formation of pure hexagonal phase with space group P63mc (186). The same can also be clearly observed form the FESEM images. The UV-Vis study shows the narrowing in band gap from 3.22 eV to 3.19 eV with incorporation of Boron in ZnO matrix. The B-doped ZnO NRs sample shows an enhanced photocurrent density of 1.31 mA/cm2 at 0.5 V (vs. Ag/AgCl), which is more than 171% enhancement compared to bare ZnO NRs (0.483 mA/cm2) in 0.1 M Na2SO4 aqueous solution. The results clearly indicates that the boron doped ZnO NRs can be used as an efficient photoelectrode material for photoelectrochemical cell.

  15. Optimization Study of Pulsed DC Nitrogen-Hydrogen Plasma in the Presence of an Active Screen Cage

    NASA Astrophysics Data System (ADS)

    Saeed, A.; W. Khan, A.; F., Jan; U. Shah, H.; Abrar, M.; Zaka-Ul-Islam, M.; Khalid, M.; Zakaullah, M.

    2014-05-01

    A glow discharge plasma nitriding reactor in the presence of an active screen cage is optimized in terms of current density, filling pressure and hydrogen concentrations using optical emission spectroscopy (OES). The samples of AISI 304 are nitrided for different treatment times under optimum conditions. The treated samples were analyzed by X-ray diffraction (XRD) to explore the changes induced in the crystallographic structure. The XRD pattern confirmed the formation of iron and chromium nitrides arising from incorporation of nitrogen as an interstitial solid solution in the iron lattice. A Vickers microhardness tester was used to evaluate the surface hardness as a function of treatment time (h). The results showed clear evidence of improved surface hardness and a substantial amount of decrease in the treatment time compared with the previous work.

  16. Effects of topical diquafosol pretreatment on intraoperative corneal wetting.

    PubMed

    Miyake, Goichiro; Ota, Ichiro; Miyake, Kensaku; Zako, Masahiro; Iwaki, Masayoshi

    2014-10-01

    To examine the effects of pretreatment with diquafosol 3.0% ophthalmic solution on corneal surface wetting during cataract surgery with intraocular lens (IOL) implantation in cases of senile cataract. Shohzankai Medical Foundation, Miyake Eye Hospital, Nagoya, Japan. Prospective randomized single-masked comparative study. Phacoemulsification and IOL implantation were performed in eyes with senile cataract. After a 2-week washout period, patients were randomly assigned to receive 1 drop of diquafosol 3.0% ophthalmic solution or artificial tears 6 times daily for 4 weeks before surgery. The main outcome measure, termed the corneal wetting property, was the time between when a clear image of the operating microscope light source appeared just after the corneal surface was irrigated with a balanced salt solution and the time at which that image began to blur. The study enrolled 51 patients (76 eyes). The mean time to corneal wetting was 50.1 seconds ± 10.8 (SD) in the diquafosol group and 45.3 ± 9.2 seconds in the artificial tears group. The difference between the 2 groups was statistically significant (P<.029). Four-week pretreatment with diquafosol 3.0% ophthalmic solution in patients with senile cataract scheduled for cataract surgery with IOL implantation was effective in enhancing the intraoperative corneal surface wetting property, which suggests improved optical clarity during surgery. No author has a financial or proprietary interest in any material or method mentioned. Copyright © 2014 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  17. Determination of refraction nonlinear index, for effect thermal, of solutions with nanoparticles of gold

    NASA Astrophysics Data System (ADS)

    Olivares-Vargas, A.; Trejo-Durán, M.; Alvarado-Méndez, E.; Cornejo-Monroy, D.; Mata-Chávez, R. I.; Estudillo-Ayala, J. M.; Castaño-Meneses, V.

    2013-09-01

    Research of nonlinear optical properties of materials for manufacturing opto-electronic devices, had a great growth in the last years. The solutions with nanoparticle metals present nonlinear optical properties. In this work we present the results of characterizing, analyzing and determining the magnitude and sign of the nonlinear refractive index, using the z-scan technique in solutions with nanoparticles of gold, lipoic acid and sodium chloride. We used a continuous Argon laser at 514 nm with variable power, an 18 cms lens, and a chopper. We determined the nonlinear refractive index in the order of 10-9. These materials have potential applications mainly as optical limiters.

  18. Use of a fiber optic probe for organic species determination

    DOEpatents

    Ekechukwu, A.A.

    1996-12-10

    A fiber optic probe is described for remotely detecting the presence and concentration organic species in aqueous solutions. The probe includes a cylindrical housing with an organic species indicator, preferably diaminonaphthyl sulfonic acid adsorbed in a silica gel (DANS-modified gel), contained in the probe`s distal end. The probe admits aqueous solutions to the probe interior for mixing within the DANS-modified gel. An optical fiber transmits light through the DANS-modified gel while the indicator reacts with organic species present in the solution, thereby shifting the location of the fluorescent peak. The altered light is reflected to a receiving fiber that carries the light to a spectrophotometer or other analysis device. 5 figs.

  19. Use of a fiber optic probe for organic species determination

    DOEpatents

    Ekechukwu, Amy A.

    1996-01-01

    A fiber optic probe for remotely detecting the presence and concentration organic species in aqueous solutions. The probe includes a cylindrical housing with an organic species indicator, preferably diaminonaphthyl sulfonic acid adsorbed in a silica gel (DANS-modified gel), contained in the probe's distal end. The probe admits aqueous solutions to the probe interior for mixing within the DANS-modified gel. An optical fiber transmits light through the DANS-modified gel while the indicator reacts with organic species present in the solution, thereby shifting the location of the fluorescent peak. The altered light is reflected to a receiving fiber that carries the light to a spectrophotometer or other analysis device.

  20. Exact solitary wave solution for higher order nonlinear Schrodinger equation using He's variational iteration method

    NASA Astrophysics Data System (ADS)

    Rani, Monika; Bhatti, Harbax S.; Singh, Vikramjeet

    2017-11-01

    In optical communication, the behavior of the ultrashort pulses of optical solitons can be described through nonlinear Schrodinger equation. This partial differential equation is widely used to contemplate a number of physically important phenomena, including optical shock waves, laser and plasma physics, quantum mechanics, elastic media, etc. The exact analytical solution of (1+n)-dimensional higher order nonlinear Schrodinger equation by He's variational iteration method has been presented. Our proposed solutions are very helpful in studying the solitary wave phenomena and ensure rapid convergent series and avoid round off errors. Different examples with graphical representations have been given to justify the capability of the method.

  1. Way for LEEPL technology to succeed in memory device application

    NASA Astrophysics Data System (ADS)

    Kim, In-Sung; Woo, Sang-Gyun; Cho, Han-Ku; Han, Woo-Sung; Moon, Joo-Tae

    2004-05-01

    Lithography for 65nm-node device is drawing a lot of attentions these days especially because lithography solution for this node is not clear and even tool makers tend to wait for the consensus in lithography roadmap to avoid the risk of erroneous amount of investment. Recently proposed concept of low energy electron-beam proximity-projection lithography (LEEPL)1,2 technology has already released its first production machine in 2003, which is being expected to cover the design rule down to 65nm-node and even smaller3. Although production of semiconductor device has been pursuing optical lithography, without any optical technology that is proved as a convincing solution for 65nm node and below, we need to take account of all the candidates. So we made an investigation on LEEPL technology and evaluated beta and first production tool to see the feasibility of printing sub-70nm resolution and of optic-first mix-and-match overlay from a chip maker"s point of view. Two different kinds of stencil masks were fabricated for the evaluation, which are fabricated in SiC and Si membrane. The former mask is for sparse contact holes(C/H) and the latter for dense C/Hs. Beta-tool showed a good resolving power of sub-70nm sparse C/Hs of SRAM with negligibly small proximity effect. It implies that LEEPL does not require much effort for proximity correction comparing to that required in optical lithography, which is one of the biggest issues in low-k1. LEEPL also showed a good capability of optic-first mix-and-match overlay correction and this is the most stringent and important functionality for optic-first mix-and-match application. However random intra-membrane image placement(IP) error that is a little bit larger than the requirement for sub-70nm node was observed, which is interpreted to come from the larger stress of 100MPa in 3X3mm2 dry-etched SiC unit membrane. For dense C/Hs, we failed, to the contrary, to obtain any good quality of stencil masks for DRAM cell patterns because of e-beam proximity effect which is unavoidable in the reversed order of front-side forward direct writing and back-side later membrane formation. Pros and cons of LEEPL technology are discussed based on the evaluation results and estimation from the memory device standpoint. We also propose a novel concept of stencil mask that can be helpful in memory device application.

  2. Investigation on structural, thermal, optical and sensing properties of meta-stable hexagonal MoO(3) nanocrystals of one dimensional structure.

    PubMed

    Chithambararaj, Angamuthuraj; Bose, Arumugam Chandra

    2011-01-01

    Hexagonal molybdenum oxide (h-MoO(3)) was synthesized by a solution based chemical precipitation technique. Analysis by X-ray diffraction (XRD) confirmed that the as-synthesized powder had a metastable hexagonal structure. The characteristic vibrational band of Mo-O was identified from Fourier transform infrared spectroscopy (FT-IR). Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images clearly depicted the morphology and size of h-MoO(3.) The morphology study showed that the product comprises one-dimensional (1D) hexagonal rods. From the electron energy loss spectroscopy (EELS) measurement, the elemental composition was investigated and confirmed from the characteristic peaks of molybdenum and oxygen. Thermogravimetric (TG) analysis on metastable MoO(3) revealed that the hexagonal phase was stable up to 430 °C and above this temperature complete transformation into a highly stable orthorhombic phase was achieved. The optical band gap energy was estimated from the Kubelka-Munk (K-M) function and was found to be 2.99 eV. Finally, the ethanol vapor-sensing behavior was investigated and the sensing response was found to vary linearly as a function of ethanol concentration in the parts per million (ppm) range.

  3. Electrolysis-induced protonation of VO2 thin film transistor for the metal-insulator phase modulation

    NASA Astrophysics Data System (ADS)

    Katase, Takayoshi; Endo, Kenji; Ohta, Hiromichi

    2016-02-01

    Compared to state-of-the-art modulation techniques, protonation is the most ideal to control the electrical and optical properties of transition metal oxides (TMOs) due to its intrinsic non-volatile operation. However, the protonation of TMOs is not typically utilized for solid-state devices because of imperative high-temperature annealing treatment in hydrogen source. Although one solution for room temperature (RT) protonation of TMOs is liquid-phase electrochemistry, it is unsuited for practical purposes due to liquid-leakage problem. Herein we demonstrate solid-state RT-protonation of vanadium dioxide (VO2), which is a well-known thermochromic TMO. We fabricated the three terminal thin-film-transistor structure on an insulating VO2 film using a water-infiltrated nanoporous glass, which serves as a solid electrolyte. For gate voltage application, water electrolysis and protonation/deprotonation of VO2 film surface occurred, leading to reversible metal-insulator phase conversion of ~11-nm-thick VO2 layer. The protonation was clearly accompanied by the structural change from an insulating monoclinic to a metallic tetragonal phase. Present results offer a new route for the development of electro-optically active solid-state devices with TMO materials by engineering RT protonation.

  4. Efficient color mixing through étendue conservation using freeform optics

    NASA Astrophysics Data System (ADS)

    Sorgato, Simone; Mohedano, Rubén.; Chaves, Julio; Cvetkovic, Aleksandra; Hernández, Maikel; Benitez, Pablo; Miñano, Juan C.; Thienpont, Hugo; Duerr, Fabian

    2015-08-01

    Today's SSL illumination market shows a clear trend to high flux packages with higher efficiency and higher CRI, realized by means of multiple color chips and phosphors. Such light sources require the optics to provide both near- and far-field color mixing. This design problem is particularly challenging for collimated luminaries, since traditional diffusers cannot be employed without enlarging the exit aperture and reducing brightness. Furthermore, diffusers compromise the light output ratio (efficiency) of the lamps to which they are applied. A solution, based on Köhler integration, consisting of a spherical cap comprising spherical microlenses on both its interior and exterior sides was presented in 2012. The diameter of this so-called Shell-Mixer was 3 times that of the chip array footprint. A new version of the Shell-Mixer, based on the Edge Ray Principle and conservation of etendue, where neither the outer shape of the cap nor the surfaces of the lenses are constrained to spheres or 2D Cartesian ovals will be shown in this work. The new shell is freeform, only twice as large as the original chip-array and equals the original model in terms of color uniformity, brightness and efficiency.

  5. Microplasma array patterning of reactive oxygen and nitrogen species onto polystyrene

    NASA Astrophysics Data System (ADS)

    Szili, Endre J.; Dedrick, James; Oh, Jun-Seok; Bradley, James W.; Boswell, Roderick W.; Charles, Christine; Short, Robert D.; Al-Bataineh, Sameer A.

    2017-02-01

    We investigate an approach for the patterning of reactive oxygen and nitrogen species (RONS) onto polystyrene using atmospheric-pressure microplasma arrays. The spectrally integrated and time-resolved optical emission from the array is characterised with respect to the applied voltage, applied-voltage frequency and pressure; and the array is used to achieve spatially resolved modification of polystyrene at three pressures: 500 Torr, 760 Torr and 1000 Torr. As determined by time-of-flight secondary ion mass spectrometry (ToF-SIMS), regions over which surface modification occurs are clearly restricted to areas that are exposed to individual microplasma cavities. Analysis of the negative-ion ToF-SIMS mass spectra from the centre of the modified microspots shows that the level of oxidation is dependent on the operating pressure, and closely correlated with the spatial distribution of the optical emission. The functional groups that are generated by the microplasma array on the polystyrene surface are shown to readily participate in an oxidative reaction in phosphate buffered saline solution (pH 7.4). Patterns of oxidised and chemically reactive functionalities could potentially be applied to the future development of biomaterial surfaces, where spatial control over biomolecule or cell function is needed.

  6. A laser-optical system to re-enter or lower low Earth orbit space debris

    NASA Astrophysics Data System (ADS)

    Phipps, Claude R.

    2014-01-01

    Collisions among existing Low Earth Orbit (LEO) debris are now a main source of new debris, threatening future use of LEO space. Due to their greater number, small (1-10 cm) debris are the main threat, while large (>10 cm) objects are the main source of new debris. Flying up and interacting with each large object is inefficient due to the energy cost of orbit plane changes, and quite expensive per object removed. Strategically, it is imperative to remove both small and large debris. Laser-Orbital-Debris-Removal (LODR), is the only solution that can address both large and small debris. In this paper, we briefly review ground-based LODR, and discuss how a polar location can dramatically increase its effectiveness for the important class of sun-synchronous orbit (SSO) objects. With 20% clear weather, a laser-optical system at either pole could lower the 8-ton ENVISAT by 40 km in about 8 weeks, reducing the hazard it represents by a factor of four. We also discuss the advantages and disadvantages of a space-based LODR system. We estimate cost per object removed for these systems. International cooperation is essential for designing, building and operating any such system.

  7. Measurement of diffusion coefficient of propylene glycol in skin tissue

    NASA Astrophysics Data System (ADS)

    Genin, Vadim D.; Bashkatov, Alexey N.; Genina, Elina A.; Tuchin, Valery V.

    2015-03-01

    Optical clearing of the rat skin under the action of propylene glycol was studied ex vivo. It was found that collimated transmittance of skin samples increased, whereas weight and thickness of the samples decreased during propylene glycol penetration in skin tissue. A mechanism of the optical clearing under the action of propylene glycol is discussed. Diffusion coefficient of propylene glycol in skin tissue ex vivo has been estimated as (1.35±0.95)×10-7 cm2/s with the taking into account of kinetics of both weight and thickness of skin samples. The presented results can be useful for enhancement of many methods of laser therapy and optical diagnostics of skin diseases and localization of subcutaneous neoplasms.

  8. The response characteristics of tetrazolium violet solutions to gamma irradiation

    NASA Astrophysics Data System (ADS)

    Emi-Reynolds, G.; Kovács, András; Fletcher, J. J.

    2007-08-01

    The dosimetry characteristics of various solutions of tetrazolium violet, TV, (2,5-diphenyl-3-(1-naphthyl)-2H-tetrazolium chloride) to gamma irradiation are reported. The optical absorption spectra of these solutions show peaks between 400 and 600 nm with a shoulder at around 550 nm. The dose response of the optical absorbance values of aqueous and aqueous-alcoholic solutions containing different concentrations of TV was measured in the 250 Gy up to 75 kGy dose range. The formation of formazan product was observed due to radiolytic reduction in both solutions. Its formation was found more pronounced in N 2-saturated as well as in alkaline solutions. The results indicate that the 1 mM TV solution can be used for food irradiation and medical sterilization dosimetry at gamma irradiation facilities.

  9. Liquid scintillators for optical fiber applications

    DOEpatents

    Franks, Larry A.; Lutz, Stephen S.

    1982-01-01

    A multicomponent liquid scintillator solution for use as a radiation-to-light converter in conjunction with a fiber optic transmission system. The scintillator includes a quantity of 1, 2, 4, 5, 3H, 6H, 1 OH, tetrahydro-8-trifluoromethyl (1) benzopyrano (9, 9a, 1-gh) quinolizin-10-one (Coumarin) as a solute in a fluor solvent such as benzyl alcohol or pseudo-cumene. The use of BIBUQ as an additional or primary solute is also disclosed.

  10. Are There Optical Solitary Wave Solutions in Linear Media with Group Velocity Dispersion?

    NASA Technical Reports Server (NTRS)

    Li, Zhonghao; Zhou, Guosheng

    1996-01-01

    A generalized exact optical bright solitary wave solution in a three dimensional dispersive linear medium is presented. The most interesting property of the solution is that it can exist in the normal group-velocity-dispersion (GVD) region. In addition, another peculiar feature is that it may achieve a condition of 'zero-dispersion' to the media so that a solitary wave of arbitrarily small amplitude may be propagated with no dependence on is pulse width.

  11. The CLEAR[TM] Problem-Solving Model: Discovering Strengths and Solutions

    ERIC Educational Resources Information Center

    Koehler, Nancy; Seger, Vikki

    2011-01-01

    This article introduces a unique team approach to planning and positive behavior support. The young person becomes a key participant in solving problems and setting goals for growth. The CLEAR Team Problem Solving model shifts the focus from deficits to strengths and solutions. The goal is to identify how a child's private logic and interpersonal…

  12. Tracking Systems for Virtual Rehabilitation: Objective Performance vs. Subjective Experience. A Practical Scenario

    PubMed Central

    Lloréns, Roberto; Noé, Enrique; Naranjo, Valery; Borrego, Adrián; Latorre, Jorge; Alcañiz, Mariano

    2015-01-01

    Motion tracking systems are commonly used in virtual reality-based interventions to detect movements in the real world and transfer them to the virtual environment. There are different tracking solutions based on different physical principles, which mainly define their performance parameters. However, special requirements have to be considered for rehabilitation purposes. This paper studies and compares the accuracy and jitter of three tracking solutions (optical, electromagnetic, and skeleton tracking) in a practical scenario and analyzes the subjective perceptions of 19 healthy subjects, 22 stroke survivors, and 14 physical therapists. The optical tracking system provided the best accuracy (1.074 ± 0.417 cm) while the electromagnetic device provided the most inaccurate results (11.027 ± 2.364 cm). However, this tracking solution provided the best jitter values (0.324 ± 0.093 cm), in contrast to the skeleton tracking, which had the worst results (1.522 ± 0.858 cm). Healthy individuals and professionals preferred the skeleton tracking solution rather than the optical and electromagnetic solution (in that order). Individuals with stroke chose the optical solution over the other options. Our results show that subjective perceptions and preferences are far from being constant among different populations, thus suggesting that these considerations, together with the performance parameters, should be also taken into account when designing a rehabilitation system. PMID:25808765

  13. Optical response of bowtie antennas

    NASA Astrophysics Data System (ADS)

    Guo, Ying-Nan; Pan, Shi; Li, Xu-Feng; Wang, Shuo; Wang, Qiao

    2010-10-01

    Optical properties of bowtie antennas are investigated using a numerical method of finite-difference time-domain (FDTD). The optical response in the antenna feed gap is simulated as functions of its geometry parameters (flare angle, arm length, apex width, thickness, gap dimension, as well as the index of substrate), which provide a clear guideline to exploit such antenna structures in practice.

  14. Hybrid accretion disks in active galactic nuclei. I - Structure and spectra

    NASA Technical Reports Server (NTRS)

    Wandel, Amri; Liang, Edison P.

    1991-01-01

    A unified treatment is presented of the two distinct states of vertically thin AGN accretion disks: a cool (about 10 to the 6th K) optically thick solution, and a hot (about 10 to the 9th K) optically thin solution. A generalized formalism and a new radiative cooling equation valid in both regimes are introduced. A new luminosity limit is found at which the hot and cool alpha solutions merge into a single solution of intermediate optical depth. Analytic solutions for the disk structure are given, and output spectra are computed numerically. This is used to demonstrate the prospect of fitting AGN broadband spectra containing both the UV bump as well as the hard X-ray and gamma-ray tail, using a single accretion disk model. Such models are found to make definite predictions about the observed spectrum, such as the relation between the hard X-ray spectral index, the UV-to-X-ray luminosity ratio, and a feature of about 1 MeV.

  15. The N+CPT resonance

    NASA Astrophysics Data System (ADS)

    Crescimanno, Michael; Hohensee, Michael; Hancox, Cindy; Phillips, David; Walsworth, Ron

    2007-06-01

    Of relevance to compact atomic frequency standards, we investigate a model of the N+CPT joint optical resonance. We compare analytical solutions of a 4-state theory, as well as numerical solutions of the optical Bloch equations, to experimental investigations of N+CPT resonances in 87Rb. Our results inform the optimization of N+CPT based frequency standards.

  16. An Inexpensive High Pressure Optical Absorption Cell for IR-VIS-UV Studies.

    ERIC Educational Resources Information Center

    Rodgers, V. E.; Angell, C. A.

    1983-01-01

    Describes an optical cell, suitable for high-pressure studies between at least -130 and +150 degrees Celsius, which may be assembled for about $50. Discusses experimental demonstration of principles involved when using the apparatus, including effects of pressure on coordination of ions in solution and on reaction rates in solution. (JN)

  17. MULTIPLICITY OF NOVA ENVELOPE SOLUTIONS AND OCCURRENCE OF OPTICALLY THICK WINDS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kato, Mariko; Hachisu, Izumi

    2009-07-10

    We revisit the occurrence condition of optically thick winds reported by Kato in 1985 and Kato and Hachisu in 1989 who mathematically examined nova envelope solutions with an old opacity and found that optically thick winds are accelerated only in massive white dwarfs (WDs) of {approx}>0.9 M{sub sun}. With the OPAL opacity we find that the optically thick wind occurs for {approx}>0.6 M{sub sun} WDs and that the occurrence of winds depends not only on the WD mass but also on the ignition mass. When the ignition mass is larger than a critical value, winds are suppressed by a density-inversionmore » layer. Such a static solution can be realized in WDs of mass {approx}0.6-0.7 M{sub sun}. We propose that sequences consisting only of static solutions correspond to slow evolutions in symbiotic novae like PU Vul because PU Vul shows no indication of strong winds in a long-lasted flat peak followed by a very slow decline in its light curve.« less

  18. Fluoride-selective optical sensor based on the dipyrrolyl-tetrathiafulvalene chromophore.

    PubMed

    Rivadehi, Shadi; Reid, Ellen F; Hogan, Conor F; Bhosale, Sheshanath V; Langford, Steven J

    2012-01-28

    A chemosensor bearing dipyrrolyl motifs as recognition sites and a tetrathiafulvalene redox tag has been evaluated as an optical and redox sensor for a series of anions (F(-), Cl(-), Br(-), HSO(4)(-), CH(3)COO(-), and H(2)PO(4)(-)) in DCM solution. The receptor shows specific optical signaling for fluoride but little electrochemical effect in solution. The solid-state performance of the sensor leads to measurable changes in water. Design implications towards better systems based on these results and other examples are discussed.

  19. pH Optrode Instrumentation

    NASA Technical Reports Server (NTRS)

    Tabacco, Mary Beth; Zhou, Quan

    1995-01-01

    pH-sensitive chromophoric reagents immobilized in porous optical fibers. Optoelectronic instrumentation system measures acidity or alkalinity of aqueous nutrient solution. Includes one or more optrodes, which are optical-fiber chemical sensors, in sense, analogous to electrodes but not subject to some of spurious effects distorting readings taken by pH electrodes. Concept of optrodes also described in "Ethylene-Vapor Optrodes" (KSC-11579). pH optrode sensor head, with lead-in and lead-out optical fibers, convenient for monitoring solutions located away from supporting electronic equipment.

  20. Planar dielectric waveguides in rotation are optical fibers: comparison with the classical model.

    PubMed

    Peña García, Antonio; Pérez-Ocón, Francisco; Jiménez, José Ramón

    2008-01-21

    A novel and simpler method to calculate the main parameters in fiber optics is presented. This method is based in a planar dielectric waveguide in rotation and, as an example, it is applied to calculate the turning points and the inner caustic in an optical fiber with a parabolic refractive index. It is shown that the solution found using this method agrees with the standard (and more complex) method, whose solutions for these points are also summarized in this paper.

  1. A fiber-optic sensor based on no-core fiber and Faraday rotator mirror structure

    NASA Astrophysics Data System (ADS)

    Lu, Heng; Wang, Xu; Zhang, Songling; Wang, Fang; Liu, Yufang

    2018-05-01

    An optical fiber sensor based on the single-mode/no-core/single-mode (SNS) core-offset technology along with a Faraday rotator mirror structure has been proposed and experimentally demonstrated. A transverse optical field distribution of self-imaging has been simulated and experimental parameters have been selected under theoretical guidance. Results of the experiments demonstrate that the temperature sensitivity of the sensor is 0.0551 nm/°C for temperatures between 25 and 80 °C, and the correlation coefficient is 0.99582. The concentration sensitivity of the device for sucrose and glucose solutions was found to be as high as 12.5416 and 6.02248 nm/(g/ml), respectively. Curves demonstrating a linear fit between wavelength shift and solution concentration for three different heavy metal solutions have also been derived on the basis of experimental results. The proposed fiber-optic sensor design provides valuable guidance for the measurement of concentration and temperature.

  2. Near-to-eye electroholography via guided-wave acousto-optics for augmented reality

    NASA Astrophysics Data System (ADS)

    Jolly, Sundeep; Savidis, Nickolaos; Datta, Bianca; Smalley, Daniel; Bove, V. Michael

    2017-03-01

    Near-to-eye holographic displays act to directly project wavefronts into a viewer's eye in order to recreate 3-D scenes for augmented or virtual reality applications. Recently, several solutions for near-to-eye electroholography have been proposed based on digital spatial light modulators in conjunction with supporting optics, such as holographic waveguides for light delivery; however, such schemes are limited by the inherent low space-bandwidth product available with current digital SLMs. In this paper, we depict a fully monolithic, integrated optical platform for transparent near-to-eye holographic display requiring no supporting optics. Our solution employs a guided-wave acousto-optic spatial light modulator implemented in lithium niobate in conjunction with an integrated Bragg-regime reflection volume hologram.

  3. Optical registration of spaceborne low light remote sensing camera

    NASA Astrophysics Data System (ADS)

    Li, Chong-yang; Hao, Yan-hui; Xu, Peng-mei; Wang, Dong-jie; Ma, Li-na; Zhao, Ying-long

    2018-02-01

    For the high precision requirement of spaceborne low light remote sensing camera optical registration, optical registration of dual channel for CCD and EMCCD is achieved by the high magnification optical registration system. System integration optical registration and accuracy of optical registration scheme for spaceborne low light remote sensing camera with short focal depth and wide field of view is proposed in this paper. It also includes analysis of parallel misalignment of CCD and accuracy of optical registration. Actual registration results show that imaging clearly, MTF and accuracy of optical registration meet requirements, it provide important guarantee to get high quality image data in orbit.

  4. RF/optical shared aperture for high availability wideband communication RF/FSO links

    DOEpatents

    Ruggiero, Anthony J; Pao, Hsueh-yuan; Sargis, Paul

    2014-04-29

    An RF/Optical shared aperture is capable of transmitting and receiving optical signals and RF signals simultaneously. This technology enables compact wide bandwidth communications systems with 100% availability in clear air turbulence, rain and fog. The functions of an optical telescope and an RF reflector antenna are combined into a single compact package by installing an RF feed at either of the focal points of a modified Gregorian telescope.

  5. RF/optical shared aperture for high availability wideband communication RF/FSO links

    DOEpatents

    Ruggiero, Anthony J; Pao, Hsueh-yuan; Sargis, Paul

    2015-03-24

    An RF/Optical shared aperture is capable of transmitting and receiving optical signals and RF signals simultaneously. This technology enables compact wide bandwidth communications systems with 100% availability in clear air turbulence, rain and fog. The functions of an optical telescope and an RF reflector antenna are combined into a single compact package by installing an RF feed at either of the focal points of a modified Gregorian telescope.

  6. Limitations and Tolerances in Optical Devices

    NASA Astrophysics Data System (ADS)

    Jackman, Neil Allan

    The performance of optical systems is limited by the imperfections of their components. Many of the devices in optical systems including optical fiber amplifiers, multimode transmission lines and multilayered media such as mirrors, windows and filters, are modeled by coupled line equations. This investigation includes: (i) a study of the limitations imposed on a wavelength multiplexed unidirectional ring by the non-uniformities of the gain spectra of Erbium-doped optical fiber amplifiers. We find numerical solutions for non-linear coupled power differential equations and use these solutions to compare the signal -to-noise ratios and signal levels at different nodes. (ii) An analytical study of the tolerances of imperfect multimode media which support forward traveling modes. The complex mode amplitudes are related by linear coupled differential equations. We use analytical methods to derive extended equations for the expected mode powers and give heuristic limits for their regions of validity. These results compare favorably to exact solutions found for a special case. (iii) A study of the tolerances of multilayered media in the presence of optical thickness imperfections. We use analytical methods including Kronecker producers, to calculate the reflection and transmission statistics of the media. Monte Carlo simulations compare well to our analytical method.

  7. Knotted optical vortices in exact solutions to Maxwell's equations

    NASA Astrophysics Data System (ADS)

    de Klerk, Albertus J. J. M.; van der Veen, Roland I.; Dalhuisen, Jan Willem; Bouwmeester, Dirk

    2017-05-01

    We construct a family of exact solutions to Maxwell's equations in which the points of zero intensity form knotted lines topologically equivalent to a given but arbitrary algebraic link. These lines of zero intensity, more commonly referred to as optical vortices, and their topology are preserved as time evolves and the fields have finite energy. To derive explicit expressions for these new electromagnetic fields that satisfy the nullness property, we make use of the Bateman variables for the Hopf field as well as complex polynomials in two variables whose zero sets give rise to algebraic links. The class of algebraic links includes not only all torus knots and links thereof, but also more intricate cable knots. While the unknot has been considered before, the solutions presented here show that more general knotted structures can also arise as optical vortices in exact solutions to Maxwell's equations.

  8. Optical Quasi-Soliton Solutions for the Cubic-Quintic Nonlinear SCHRÖDINGER Equation with Variable Coefficients

    NASA Astrophysics Data System (ADS)

    Yang, Qin; Zhang, Jie-Fang

    Optical quasi-soliton solutions for the cubic-quintic nonlinear Schrödinger equation (CQNLSE) with variable coefficients are considered. Based on the extended tanh-function method, we not only successfully obtained bright and dark quasi-soliton solutions, but also obtained the kink quasi-soliton solutions under certain parametric conditions. We conclude that the quasi-solitons induced by the combined effects of the group velocity dispersion (GVD) distribution, the nonlinearity distribution, higher-order nonlinearity distribution, and the amplification or absorption coefficient are quite different from those of the solitons induced only by the combined effects of the GVD, the nonlinearity distribution, and the amplification or absorption coefficient without considering the higher-order nonlinearity distribution (i.e. α(z)=0). Furthermore, we choose appropriate optical fiber parameters D(z) and R(z) to control the velocity of quasi-soliton and time shift, and discuss the evolution behavior of the special quasi-soliton.

  9. Resonant optical pulses on a continuous-wave background in two-level active media

    NASA Astrophysics Data System (ADS)

    Li, Sitai; Biondini, Gino; Kovačič, Gregor; Gabitov, Ildar

    2018-01-01

    We present exact N-soliton optical pulses riding on a continuous-wave (c.w.) beam that propagate through and interact with a two-level active optical medium. Their representation is derived via an appropriate generalization of the inverse scattering transform for the corresponding Maxwell-Bloch equations. We describe the single-soliton solutions in detail and classify them into several distinct families. In addition to the analogues of traveling-wave soliton pulses that arise in the absence of a c.w. beam, we obtain breather-like structures, periodic pulse-trains and rogue-wave-type (i.e., rational) pulses, whose existence is directly due to the presence of the c.w. beam. These soliton solutions are the analogues for Maxwell-Bloch systems of the four classical solution types of the focusing nonlinear Schrödinger equation with non-zero background, although the physical behavior of the corresponding solutions is quite different.

  10. Chirped femtosecond pulses in the higher-order nonlinear Schrödinger equation with non-Kerr nonlinear terms and cubic-quintic-septic nonlinearities

    NASA Astrophysics Data System (ADS)

    Triki, Houria; Biswas, Anjan; Milović, Daniela; Belić, Milivoj

    2016-05-01

    We consider a high-order nonlinear Schrödinger equation with competing cubic-quintic-septic nonlinearities, non-Kerr quintic nonlinearity, self-steepening, and self-frequency shift. The model describes the propagation of ultrashort (femtosecond) optical pulses in highly nonlinear optical fibers. A new ansatz is adopted to obtain nonlinear chirp associated with the propagating femtosecond soliton pulses. It is shown that the resultant elliptic equation of the problem is of high order, contains several new terms and is more general than the earlier reported results, thus providing a systematic way to find exact chirped soliton solutions of the septic model. Novel soliton solutions, including chirped bright, dark, kink and fractional-transform soliton solutions are obtained for special choices of parameters. Furthermore, we present the parameter domains in which these optical solitons exist. The nonlinear chirp associated with each of the solitonic solutions is also determined. It is shown that the chirping is proportional to the intensity of the wave and depends on higher-order nonlinearities. Of special interest is the soliton solution of the bright and dark type, determined for the general case when all coefficients in the equation have nonzero values. These results can be useful for possible chirped-soliton-based applications of highly nonlinear optical fiber systems.

  11. Analog signal processing for optical coherence imaging systems

    NASA Astrophysics Data System (ADS)

    Xu, Wei

    Optical coherence tomography (OCT) and optical coherence microscopy (OCM) are non-invasive optical coherence imaging techniques, which enable micron-scale resolution, depth resolved imaging capability. Both OCT and OCM are based on Michelson interferometer theory. They are widely used in ophthalmology, gastroenterology and dermatology, because of their high resolution, safety and low cost. OCT creates cross sectional images whereas OCM obtains en face images. In this dissertation, the design and development of three increasingly complicated analog signal processing (ASP) solutions for optical coherence imaging are presented. The first ASP solution was implemented for a time domain OCT system with a Rapid Scanning Optical Delay line (RSOD)-based optical signal modulation and logarithmic amplifier (Log amp) based demodulation. This OCT system can acquire up to 1600 A-scans per second. The measured dynamic range is 106dB at 200A-scan per second. This OCT signal processing electronics includes an off-the-shelf filter box with a Log amp circuit implemented on a PCB board. The second ASP solution was developed for an OCM system with synchronized modulation and demodulation and compensation for interferometer phase drift. This OCM acquired micron-scale resolution, high dynamic range images at acquisition speeds up to 45,000 pixels/second. This OCM ASP solution is fully custom designed on a perforated circuit board. The third ASP solution was implemented on a single 2.2 mm x 2.2 mm complementary metal oxide semiconductor (CMOS) chip. This design is expandable to a multiple channel OCT system. A single on-chip CMOS photodetector and ASP channel was used for coherent demodulation in a time domain OCT system. Cross-sectional images were acquired with a dynamic range of 76dB (limited by photodetector responsivity). When incorporated with a bump-bonded InGaAs photodiode with higher responsivity, the expected dynamic range is close to 100dB.

  12. Electrical and optical evaluation aspects of public lighting systems

    NASA Astrophysics Data System (ADS)

    Tulbure, Adrian; Marc, Gheorghe; Kurt, Ünal

    2016-12-01

    This paper briefs a few issues regarding the technical validation of public lighting solutions. The novelty of the work is justified by the fact that it combines technical legislation in force [1], with practical analysis procedures [2]. Thus, in order to select the optimal solution, the paper describes a case study of measurement procedure which confirms the high electrical and optical characteristics [3] of the proposed solutions. At the end of the contribution, comparative design purposes for the two versions of modern street lighting are presented.

  13. Large-area graphene films by simple solution casting of edge-selectively functionalized graphite.

    PubMed

    Bae, Seo-Yoon; Jeon, In-Yup; Yang, Jieun; Park, Noejung; Shin, Hyeon Suk; Park, Sungjin; Ruoff, Rodney S; Dai, Liming; Baek, Jong-Beom

    2011-06-28

    We report edge-selective functionalization of graphite (EFG) for the production of large-area uniform graphene films by simply solution-casting EFG dispersions in dichloromethane on silicon oxide substrates, followed by annealing. The resultant graphene films show ambipolar transport properties with sheet resistances of 0.52-3.11 kΩ/sq at 63-90% optical transmittance. EFG allows solution processing methods for the scalable production of electrically conductive, optically transparent, and mechanically robust flexible graphene films for use in practice.

  14. Whole blood clot optical clearing for nondestructive 3D imaging and quantitative analysis

    PubMed Central

    Höök, Peter; Brito-Robinson, Teresa; Kim, Oleg; Narciso, Cody; Goodson, Holly V.; Weisel, John W.; Alber, Mark S.; Zartman, Jeremiah J.

    2017-01-01

    A technological revolution in both light and electron microscopy imaging now allows unprecedented views of clotting, especially in animal models of hemostasis and thrombosis. However, our understanding of three-dimensional high-resolution clot structure remains incomplete since most of our recent knowledge has come from studies of relatively small clots or thrombi, due to the optical impenetrability of clots beyond a few cell layers in depth. Here, we developed an optimized optical clearing method termed cCLOT that renders large whole blood clots transparent and allows confocal imaging as deep as one millimeter inside the clot. We have tested this method by investigating the 3D structure of clots made from reconstituted pre-labeled blood components yielding new information about the effects of clot contraction on erythrocytes. Although it has been shown recently that erythrocytes are compressed to form polyhedrocytes during clot contraction, observations of this phenomenon have been impeded by the inability to easily image inside clots. As an efficient and non-destructive method, cCLOT represents a powerful research tool in studying blood clot structure and mechanisms controlling clot morphology. Additionally, cCLOT optical clearing has the potential to facilitate imaging of ex vivo clots and thrombi derived from healthy or pathological conditions. PMID:28856043

  15. Effects of brash removal after clear felling on soil and soil-solution chemistry and field-layer biomass in an experimental nitrogen gradient.

    PubMed

    Ring, E; Högbom, L; Nohrstedt, H O

    2001-10-12

    Biofuels, such as brash from forest fellings, have been proposed as an alternative energy source. Brash removal may affect the sustainability of forest production, e.g., through a change in the availability of cations and N in the soil. We report initial effects of brash removal on inorganic N content in humus and mineral soil, soil-solution chemistry, and field-layer biomass after clear felling an N-fertilisation experiment in central Sweden. The experiment comprised six different fertiliser levels, ranging from 0 to 600 kg N ha(-1). Urea was given every 5th year during 1967 to 1982 to replicated plots, giving total doses of 0 to 2400 kg N ha(-1). Clear felling took place in 1995, 13 years after the last fertilisation. The removal of brash decreased the NO3- content in the humus layer after clear felling. A decrease in the NO3- concentration of the soil solution was indicated during most of the study period as well. No effect of the previous N fertilisation was found in the humus layer, but in the mineral soil there was an increase in NO3- content for the highest N dose after clear felling ( p = 0.06). The soil-solution chemistry and the field-layer biomass showed an irregular pattern with no consistent effects of brash removal or previous fertilisation.

  16. Changes in optical spectra of silver nanoparticles doped europium ions

    NASA Astrophysics Data System (ADS)

    Rasmagin, S. I.; Krasovskii, V. I.; Novikov, I. K.; Kryshtob, V. I.; Kazaryan, M. A.

    2018-04-01

    Colloidal solutions of Ag silver nanoparticles were studied in the presence of Eu3+ ions and in the absence of their. Silver nanoparticles were created by the method of green synthesis using an aqueous solution of mint. Optical and electronic spectroscopy have been used to explore the interaction of these ions with silver nanoparticles.

  17. Chemical micro-sensor

    DOEpatents

    Ruggiero, Anthony J.

    2005-05-03

    An integrated optical capillary electrophoresis system for analyzing an analyte. A modulated optical pump beam impinges on an capillary containing the analyte/buffer solution which is separated by electrophoresis. The thermally-induced change in the index of refraction of light in said electrophoresis capillary is monitored using an integrated micro-interferometer. The interferometer includes a first interferometer arm intersecting the electrophoresis capillary proximate the excitation beam and a second, reference interferometer arm. Changes in index of refraction in the analyte measured by interrogating the interferometer state using white light interferometry and a phase-generated carrier demodulation technique. Background thermo-optical activity in the buffer solution is cancelled by splitting the pump beam and exciting pure buffer solution in a second section of capillary where it crosses the reference arm of the interferometer.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prakash, S. Arun; Malathi, V.; Mani Rajan, M. S., E-mail: senthilmanirajanofc@gmail.com

    We obtain the bright similariton solutions for generalized inhomogeneous nonlinear Schrödinger equation (GINLSE) which governs the pulse propagation in a tapered graded index diffraction decreasing waveguide (DDW). The exact solutions have been worked out by employing similarity transformations which involve the mapping of the GINLSE to standard NLSE for the certain conditions of the parameters. By making use of the exact analytical solutions, we have investigated the dynamical behavior of optical similariton pairs and have suggested the methods to control them as they propagate through DDW. Moreover, pulse width of similariton is controlled through various profiles. These results are helpfulmore » to understand the similaritons in DDW and can be potentially useful for future experiments in optical communications which involve optical amplifiers and long-haul telecommunication networks.« less

  19. Use of fractional laser microablation of skin for improvement of its immersion clearing

    NASA Astrophysics Data System (ADS)

    Kolesnikova, Ekaterina A.; Kolesnikov, Aleksandr S.; Genina, Elina A.; Dolotov, Leonid E.; Tuchina, Darya K.; Bashkatov, Alexey N.; Tuchin, Valery V.

    2013-02-01

    We are proposing a new method for enhancement of optical clearing agent delivery into the skin using fractional laser microablation of the skin surface. The Palomar Lux2940 erbium laser with the wavelength 2940 nm and pulse duration of 5 ms was used as a light source. Two regimes of laser action were used in the experiments: the first one realized microablation of skin upper layer and the second one created microchannels in skin. As optical clearing agents mineral oil and PEG-300 were used. In vivo studies were carried out with white outbred rats. Both parameters: the permeability coefficient of the agents in the tissue and the optical probing depth were measured using the OCT system at a wavelength of 930 nm. The following values of the permeability coefficient of the skin with microablation were obtained: (3.41+/-0.46)×10-5 cm/s and (2.35+/-0.30)×10-5 cm/s for mineral oil and PEG-300, respectively, at the use of the surface microablation and (3.32+/-0.09)×10-5 cm/s and (3.61+/-0.34)×10-5 cm/s for mineral oil and PEG-300, respectively, at the use of the microporation. The results have shown that the joint application of mineral oil with microablation in the first regime promotes maximal (nearly 2-folds) increasing of optical probing depth in 30 min. Obtained data can be used for development of optical diagnostic methods of skin diseases.

  20. Conformal self-assembled thin films for optical pH sensors

    NASA Astrophysics Data System (ADS)

    Topasna, Daniela M.; Topasna, Gregory A.; Liu, Minghanbo; Tseng, Ching-Hung

    2016-04-01

    Simple, reliable, lightweight, and inexpensive thin films based sensors are still in intense development and high demand in many applications such as biomedical, industrial, environmental, military, and consumer products. One important class of sensors is the optical pH sensor. In addition, conformal thin film based sensors extend the range of application for pH optical sensors. We present the results on the fabrication and characterization of optical pH sensing coatings made through ionic self-assembled technique. These thin films are based on the combination of a polyelectrolyte and water-soluble organic dye molecule Direct Yellow 4. A series of films was fabricated and characterized in order to determine the optimized parameters of the polymer and of the organic dye solutions. The optical pH responses of these films were also studied. The transparent films were immersed in solutions at various temperature and pH values. The films are stable when immersed in solutions with pH below 9.0 and temperatures below 90 °C and they maintain their performance after longer immersion times. We also demonstrate the functionality of these coatings as conformal films.

  1. A Study on the Plasmonic Properties of Silver Core Gold Shell Nanoparticles: Optical Assessment of the Particle Structure

    NASA Astrophysics Data System (ADS)

    Mott, Derrick; Lee, JaeDong; Thi Bich Thuy, Nguyen; Aoki, Yoshiya; Singh, Prerna; Maenosono, Shinya

    2011-06-01

    This paper reports a qualitative comparison between the optical properties of a set of silver core, gold shell nanoparticles with varying composition and structure to those calculated using the Mie solution. To achieve this, silver nanoparticles were synthesized in aqueous phase from a silver hydroxide precursor with sodium acrylate as dual reducing-capping agent. The particles were then coated with a layer of gold with controllable thickness through a reduction-deposition process. The resulting nanoparticles reveal well defined optical properties that make them suitable for comparison to ideal calculated results using the Mie solution. The discussion focuses on the correlation between the synthesized core shell nanoparticles with varying Au shell thickness and the Mie solution results in terms of the optical properties. The results give insight in how to design and synthesize silver core, gold shell nanoparticles with controllable optical properties (e.g., SPR band in terms of intensity and position), and has implications in creating nanoparticle materials to be used as biological probes and sensing elements.

  2. Optical bio-sniffer for ethanol vapor using an oxygen-sensitive optical fiber.

    PubMed

    Mitsubayashi, Kohji; Kon, Takuo; Hashimoto, Yuki

    2003-11-30

    An optical bio-sniffer for ethanol was constructed by immobilizing alcohol oxidase (AOD) onto a tip of a fiber optic oxygen sensor with a tube-ring, using an oxygen sensitive ruthenium organic complex (excitation, 470 nm; fluorescent, 600 nm). A reaction unit for circulating buffer solution was applied to the tip of the device. After the experiment in the liquid phase, the sniffer-device was applied for gas analysis using a gas flow measurement system with a gas generator. The optical device was applied to detect the oxygen consumption induced by AOD enzymatic reaction with alcohol application. The sensor in the liquid phase was used to measure ethanol solution from 0.50 to 9.09 mmol/l. Then, the bio-sniffer was calibrated against ethanol vapor from 0.71 to 51.49 ppm with good gas-selectivity based on the AOD substrate specificity. The bio-sniffer with the reaction unit was also used to monitor the concentration change of gaseous ethanol by rinsing and cleaning the fiber tip and the enzyme membrane with buffer solution.

  3. Raman intensity as a probe of concentration near a crystal growing in solution

    NASA Technical Reports Server (NTRS)

    Wilkinson, R. Allen

    1989-01-01

    The feasibility of using Raman spectral scattering signals for measurements of concentration profiles near a crystal interface during growth or dissolution is discussed. With KH2PO4 (KDP) as a test material, optical multichannel analyzer (OMA) detection of a solute Raman vibrational band provided direct quantification of solute concentration with band intensity. The intersection of incident laser and Raman collection optics provided 3-D selective point measurements of the solution concentration field. Unlike many other techniques, the Raman band intensity is not sensitive to the typical temperature variations. Precision calibration of Raman intensity versus KDP concentration with less than 1 pct standard deviation error levels was demonstrated. A fiber optic, which sampled incident laser intensity and coupled it to the OMA, provided a fully synchronized monitor of fluctuations in laser power to correlate with observed Raman signals. With 1 W of laser power at the sample, good data statistics required eight repeated data collections at approximately 2.5 min collection. The accumulated time represents the concentration measurement time at one spatial location. Photomicroscopy documented a 30 micrometer diameter by 200 micrometer of laser Raman scattering region in the solution near the crystal surface. The laser beam was able to approach up to 25 micrometer from the crystal surface. However, a crystal surface reflected intensity contribution was weakly detectable. Nucleated microcrystals were seen in the crystal-growing solution. These microcrystals convect right up to the crystal surface and indicate no quiet diffusion region under normal gravity conditions. Translation of the solution cell with respect to the optics caused systematic intensity errors.

  4. Long-term effects of rainforest disturbance on the nutrient composition of throughfall, organic layer percolate and soil solution at Mt. Kilimanjaro.

    PubMed

    Schrumpf, Marion; Axmacher, Jan C; Zech, Wolfgang; Lehmann, Johannes; Lyaruu, Herbert V C

    2007-04-15

    At the lower parts of the forest belt at Mt. Kilimanjaro, selective logging has led to a mosaic of mature forest, old secondary forests ( approximately 60 years), and old clearings ( approximately 10 years) covered by shrub vegetation. These variations in the vegetation are reflected by differences in nutrient leaching from the canopy and in both amount and quality of litter reaching the ground, thereby also influencing mineralization rates and the composition of seepage water in litter percolate and soil solution. The aim of this study was to investigate how above- and belowground nutrient dynamics vary between regeneration stages, and if forest regeneration at the clearings is hampered by a deterioration of abiotic site conditions. K, Mg, Ca, Na and N compounds were analysed in rainfall, throughfall, organic layer percolate and the soil solution to a depth of 1.00 m at three clearings, three secondary forest and four mature forest sites. Element fluxes via throughfall showed only small variations among regeneration stages except for K and NO(3)-N. With 57-83 kg ha(-1) a(-1)and 2.6-4.1 kg ha(-1) a(-1) respectively, K and NO(3)-N fluxes via throughfall were significantly higher at the clearings than at the mature forest sites (32-37 and 0.7-1.0 kg ha(-1) a(-1) for K and NO(3)-N). In organic layer percolate and in soil solution at 0.15-m soil depth, concentrations of K, Mg, Ca and N were highest at the clearings. In the organic layer percolate, median K concentrations were e.g. 7.4 mg l(-1) for the clearings but only 1.4 mg l(-1) for the mature forests, and for NO(3)-N, median concentrations were 3.1 mg l(-1) for the clearings but only 0.92 mg l(-1) for the mature forest sites. Still, differences in annual means between clearings and mature forests were not always significant due to a high variability within the clearings. With the exception of NO(3)-N, belowground nutrient concentrations in secondary forests ranged between concentrations in mature forests and clearings. Vegetation type-specific differences decreased with increasing soil depths in the soil solution. Overall, the opening of the forest led to a higher spatial and seasonal variation of nutrient concentrations in the seepage water. These results suggest differences in both mineralization rates and in nutrient budgeting at different regeneration stages. Since nutrient availability was highest at the clearings and no compaction of the soil was observed, deterioration of soil properties did not seem to be the main reason for the impeded regeneration on the clearings.

  5. An optical clearing technique for plant tissues allowing deep imaging and compatible with fluorescence microscopy.

    PubMed

    Warner, Cherish A; Biedrzycki, Meredith L; Jacobs, Samuel S; Wisser, Randall J; Caplan, Jeffrey L; Sherrier, D Janine

    2014-12-01

    We report on a nondestructive clearing technique that enhances transmission of light through specimens from diverse plant species, opening unique opportunities for microscope-enabled plant research. After clearing, plant organs and thick tissue sections are amenable to deep imaging. The clearing method is compatible with immunocytochemistry techniques and can be used in concert with common fluorescent probes, including widely adopted protein tags such as GFP, which has fluorescence that is preserved during the clearing process. © 2014 American Society of Plant Biologists. All Rights Reserved.

  6. The Advent of WDM and the All-Optical Network: A Reality Check.

    ERIC Educational Resources Information Center

    Lutkowitz, Mark

    1998-01-01

    Discussion of the telecommunications industry focuses on WDM (wavelength division multiplexing) as a solution for dealing with capacity constraints. Highlights include fiber optic technology; cross-connecting and switching wavelengths; SONET (Synchronous Optical Network) and wavelength networking; and optical TDM (Time Division Multiplexing). (LRW)

  7. Optical Design of the LSST Camera

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olivier, S S; Seppala, L; Gilmore, K

    2008-07-16

    The Large Synoptic Survey Telescope (LSST) uses a novel, three-mirror, modified Paul-Baker design, with an 8.4-meter primary mirror, a 3.4-m secondary, and a 5.0-m tertiary feeding a camera system that includes a set of broad-band filters and refractive corrector lenses to produce a flat focal plane with a field of view of 9.6 square degrees. Optical design of the camera lenses and filters is integrated with optical design of telescope mirrors to optimize performance, resulting in excellent image quality over the entire field from ultra-violet to near infra-red wavelengths. The LSST camera optics design consists of three refractive lenses withmore » clear aperture diameters of 1.55 m, 1.10 m and 0.69 m and six interchangeable, broad-band, filters with clear aperture diameters of 0.75 m. We describe the methodology for fabricating, coating, mounting and testing these lenses and filters, and we present the results of detailed tolerance analyses, demonstrating that the camera optics will perform to the specifications required to meet their performance goals.« less

  8. Comparison of optical projection tomography and optical coherence tomography for assessment of murine embryonic development

    NASA Astrophysics Data System (ADS)

    Singh, Manmohan; Nair, Achuth; Vadakkan, Tegy; Piazza, Victor; Udan, Ryan; Frazier, Michael V.; Janecek, Trevor; Dickinson, Mary E.; Larin, Kirill V.

    2015-03-01

    The murine model is a common model for studying developmental diseases. In this study, we compare the performance of the relatively new method of Optical Projection Tomography (OPT) to the well-established technique of Optical Coherence Tomography (OCT) to assess murine embryonic development at three stages, 9.5, 11.5, and 13.5 days post conception. While both methods can provide spatial resolution at the micrometer scale, OPT can provide superior imaging depth compared to OCT. However, OPT requires samples to be fixed, placed in an immobilization media such as agar, and cleared before imaging. Because OCT does not require fixing, it can be used to image embryos in vivo and in utero. In this study, we compare the efficacy of OPT and OCT for imaging murine embryonic development. The data demonstrate the superior capability of OPT for imaging fine structures with high resolution in optically-cleared embryos while only OCT can provide structural and functional imaging of live embryos ex vivo and in utero with micrometer scale resolution.

  9. How Well Can Infrared Sounders Observe the Atmosphere and Surface Through Clouds?

    NASA Technical Reports Server (NTRS)

    Zhou, Daniel K.; Larar, Allen M.; Liu, Xu; Smith, William L.; Strow, L. Larrabee; Yang, Ping

    2010-01-01

    Infrared sounders, such as the Atmospheric Infrared Sounder (AIRS), the Infrared Atmospheric Sounding Interferometer (IASI), and the Cross-track Infrared sounder (CrIS), have a cloud-impenetrable disadvantage in observing the atmosphere and surface under opaque cloudy conditions. However, recent studies indicate that hyperspectral, infrared sounders have the ability to detect cloud effective-optical and microphysical properties and to penetrate optically thin clouds in observing the atmosphere and surface to a certain degree. We have developed a retrieval scheme dealing with atmospheric conditions with cloud presence. This scheme can be used to analyze the retrieval accuracy of atmospheric and surface parameters under clear and cloudy conditions. In this paper, we present the surface emissivity results derived from IASI global measurements under both clear and cloudy conditions. The accuracy of surface emissivity derived under cloudy conditions is statistically estimated in comparison with those derived under clear sky conditions. The retrieval error caused by the clouds is shown as a function of cloud optical depth, which helps us to understand how well infrared sounders can observe the atmosphere and surface through clouds.

  10. Large core plastic planar optical splitter fabricated by 3D printing technology

    NASA Astrophysics Data System (ADS)

    Prajzler, Václav; Kulha, Pavel; Knietel, Marian; Enser, Herbert

    2017-10-01

    We report on the design, fabrication and optical properties of large core multimode optical polymer splitter fabricated using fill up core polymer in substrate that was made by 3D printing technology. The splitter was designed by the beam propagation method intended for assembling large core waveguide fibers with 735 μm diameter. Waveguide core layers were made of optically clear liquid adhesive, and Veroclear polymer was used as substrate and cover layers. Measurement of optical losses proved that the insertion optical loss was lower than 6.8 dB in the visible spectrum.

  11. Quantitative color measurement of pH indicator paper using trichromatic LEDs and TCS230 color sensor

    NASA Astrophysics Data System (ADS)

    Ghorude, T. N.; Chaudhari, A. L.; Shaligram, A. D.

    2008-11-01

    Quantitative analysis of pH indicator paper color is needed in the various fields. An indigenously developed Tristimulus colorimeter is used in this work for pH Indicator paper color measurement. The colorimeter uses Trichromatic RGB LEDs and a programmable color light to frequency converter (TCS230), combining configurable silicon photodiodes and a current to frequency converter on a single monolithic CMOS integrated circuit. The output is a square wave (50% duty cycle) with frequency directly proportional to light intensity. Digital input and digital output allow directly to a microcontroller. The light to frequency converter reads an 8*8 array of photodiodes. Sixteen photodiodes have red filters, 16 photodiodes have green filters, 16 photodiodes have blue filters, and 16 photodiodes are clear with no filters. All 16 photodiodes of the same colors are connected in parallel and type of photodiode the device uses during operation is pin selectable. Solutions having different standard pH were prepared and indicator paper was dipped in solution, it shows change in color. Using the developed RGB colorimeter chromaticity coordinates were measured and compared with the chromaticity coordinates measured using Ocean Optics HR-4000 high resolution spectrophotometer.

  12. Optical Brain Imaging: A Powerful Tool for Neuroscience.

    PubMed

    Zhu, Xinpei; Xia, Yanfang; Wang, Xuecen; Si, Ke; Gong, Wei

    2017-02-01

    As the control center of organisms, the brain remains little understood due to its complexity. Taking advantage of imaging methods, scientists have found an accessible approach to unraveling the mystery of neuroscience. Among these methods, optical imaging techniques are widely used due to their high molecular specificity and single-molecule sensitivity. Here, we overview several optical imaging techniques in neuroscience of recent years, including brain clearing, the micro-optical sectioning tomography system, and deep tissue imaging.

  13. High quality adaptive optics zoom with adaptive lenses

    NASA Astrophysics Data System (ADS)

    Quintavalla, M.; Santiago, F.; Bonora, S.; Restaino, S.

    2018-02-01

    We present the combined use of large aperture adaptive lens with large optical power modulation with a multi actuator adaptive lens. The Multi-actuator Adaptive Lens (M-AL) can correct up to the 4th radial order of Zernike polynomials, without any obstructions (electrodes and actuators) placed inside its clear aperture. We demonstrated that the use of both lenses together can lead to better image quality and to the correction of aberrations of adaptive optics optical systems.

  14. Optical Peregrine rogue waves of self-induced transparency in a resonant erbium-doped fiber.

    PubMed

    Chen, Shihua; Ye, Yanlin; Baronio, Fabio; Liu, Yi; Cai, Xian-Ming; Grelu, Philippe

    2017-11-27

    The resonant interaction of an optical field with two-level doping ions in a cryogenic optical fiber is investigated within the framework of nonlinear Schrödinger and Maxwell-Bloch equations. We present explicit fundamental rational rogue wave solutions in the context of self-induced transparency for the coupled optical and matter waves. It is exhibited that the optical wave component always features a typical Peregrine-like structure, while the matter waves involve more complicated yet spatiotemporally balanced amplitude distribution. The existence and stability of these rogue waves is then confirmed by numerical simulations, and they are shown to be excited amid the onset of modulation instability. These solutions can also be extended, using the same analytical framework, to include higher-order dispersive and nonlinear effects, highlighting their universality.

  15. Phase shift of TE and TM modes in an optical fiber due to axial strain (exact solution)

    NASA Technical Reports Server (NTRS)

    Egalon, Claudio O.; Rogowski, Robert S.

    1992-01-01

    Axial strain may be determined by monitoring the phase shift of modes of a variety of optical fiber sensors. In this paper, the exact solution of a circular optical fiber is used to calculate the phase shift of the TE and TM modes. Whenever an optical fiber is stressed, the optical path length, the index of refraction, and the propagation constants of each fiber mode change. In consequence, the modal phase term, beta(ln)z, of the fields is shifted by an amount Delta phi. In certain cases, it is desirable to control the phase shift term in order to make the fiber either more or less sensitive to certain kinds of strain. It is shown that it can be accomplished by choosing appropriate fiber parameters.

  16. Quantum noise of a Bose-Einstein condensate in an optical cavity, correlations, and entanglement

    NASA Astrophysics Data System (ADS)

    Szirmai, G.; Nagy, D.; Domokos, P.

    2010-04-01

    A Bose-Einstein condensate of ultracold atoms inside the field of a laser-driven optical cavity exhibits dispersive optical bistability. We describe this system by using mean-field approximation and by analyzing the correlation functions of the linearized quantum fluctuations around the mean-field solution. The entanglement and the statistics of the atom-field quadratures are given in the stationary state. It is shown that the mean-field solution, that is, the Bose-Einstein condensate, is robust against entanglement generation for most of the phase diagram.

  17. Exact optical solitons in (n + 1)-dimensions with anti-cubic nonlinearity

    NASA Astrophysics Data System (ADS)

    Younis, Muhammad; Shahid, Iram; Anbreen, Sumaira; Rizvi, Syed Tahir Raza

    2018-02-01

    The paper studies the propagation of optical solitons in (n + 1)-dimensions under anti-cubic law of nonlinearity. The bright, dark and singular optical solitons are extracted using the extended trial equation method. The constraint conditions, for the existence of these solitons, are also listed. Additionally, a couple of other solutions known as singular periodic and Jacobi elliptic solutions, fall out as a by-product of this scheme. The obtained results are new and reported first time in (n + 1)-dimensions with anti-cubic law of nonlinearity.

  18. Z-scan and optical limiting properties of Hibiscus Sabdariffa dye

    NASA Astrophysics Data System (ADS)

    Diallo, A.; Zongo, S.; Mthunzi, P.; Rehman, S.; Alqaradawi, S. Y.; Soboyejo, W.; Maaza, M.

    2014-12-01

    The intensity-dependent refractive index n 2 and the nonlinear susceptibility χ (3) of Hibiscus Sabdariffa dye solutions in the nanosecond regime at 532 nm are reported. More presicely, the variation of n 2, β, and real and imaginary parts of χ (3) versus the natural dye extract concentration has been carried out by z-scan and optical limiting techniques. The third-order nonlinearity of the Hibiscus Sabdariffa dye solutions was found to be dominated by nonlinear refraction, which leads to strong optical limiting of laser.

  19. Development of Extinction Imagers for the Determination of Atmospheric Optical Extinction

    DTIC Science & Technology

    2014-08-01

    system resulting from the effects of both the optics and the camera system (including the electronics). The MSI sensor includes a fiber optic taper...small dots in Fig. 7-1 are due to the fiber optic taper in the system. The brighter region near the center is due to the lens optics. To apply the...a black target wliich was a hollow black box. Clearly it would be a major advantage if we could use "targets of opportunity" from a ship, and in

  20. Methods for globally treating silica optics to reduce optical damage

    DOEpatents

    Miller, Philip Edward; Suratwala, Tayyab Ishaq; Bude, Jeffrey Devin; Shen, Nan; Steele, William Augustus; Laurence, Ted Alfred; Feit, Michael Dennis; Wong, Lana Louie

    2012-11-20

    A method for preventing damage caused by high intensity light sources to optical components includes annealing the optical component for a predetermined period. Another method includes etching the optical component in an etchant including fluoride and bi-fluoride ions. The method also includes ultrasonically agitating the etching solution during the process followed by rinsing of the optical component in a rinse bath.

  1. An economic analysis on optical Ethernet in the access network

    NASA Astrophysics Data System (ADS)

    Kim, Sung Hwi; Nam, Dohyun; Yoo, Gunil; Kim, WoonHa

    2004-04-01

    Nowadays, Broadband service subscribers have increased exponentially and have almost saturated in Korea. Several types of solutions for broadband service applied to the field. Among several types of broadband services, most of subscribers provided xDSL service like ADSL or VDSL. Usually, they who live in an apartment provided Internet service by Ntopia network as FTTC structure that is a dormant network in economical view at KT. Under competitive telecom environment for new services like video, we faced with needing to expand or rebuild portions of our access networks, are looking for ways to provide any service that competitors might offer presently or in the near future. In order to look for new business model like FTTH service, we consider deploying optical access network. In spite of numerous benefits of PON until now, we cannot believe that PON is the best solution in Korea. Because we already deployed optical access network of ring type feeder cable and have densely population of subscribers that mainly distributed inside 6km from central office. So we try to utilize an existing Ntopia network for FTTH service under optical access environment. Despite of such situations, we try to deploy PON solution in the field as FTTC or FTTH architecture. Therefore we analyze PON structure in comparison with AON structure in order to look for optimized structure in Korea. At first, we describe the existing optical access networks and network architecture briefly. Secondly we investigate the cost of building optical access networks by modeling cost functions on AON and PON structure which based on Ethernet protocol, and analyze two different network architectures according to different deployment scenarios: Urban, small town, rural. Finally we suggest the economic and best solution with PON structure to optimize to optical access environment of KT.

  2. An asymptotic preserving unified gas kinetic scheme for gray radiative transfer equations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, Wenjun, E-mail: sun_wenjun@iapcm.ac.cn; Jiang, Song, E-mail: jiang@iapcm.ac.cn; Xu, Kun, E-mail: makxu@ust.hk

    The solutions of radiative transport equations can cover both optical thin and optical thick regimes due to the large variation of photon's mean-free path and its interaction with the material. In the small mean free path limit, the nonlinear time-dependent radiative transfer equations can converge to an equilibrium diffusion equation due to the intensive interaction between radiation and material. In the optical thin limit, the photon free transport mechanism will emerge. In this paper, we are going to develop an accurate and robust asymptotic preserving unified gas kinetic scheme (AP-UGKS) for the gray radiative transfer equations, where the radiation transportmore » equation is coupled with the material thermal energy equation. The current work is based on the UGKS framework for the rarefied gas dynamics [14], and is an extension of a recent work [12] from a one-dimensional linear radiation transport equation to a nonlinear two-dimensional gray radiative system. The newly developed scheme has the asymptotic preserving (AP) property in the optically thick regime in the capturing of diffusive solution without using a cell size being smaller than the photon's mean free path and time step being less than the photon collision time. Besides the diffusion limit, the scheme can capture the exact solution in the optical thin regime as well. The current scheme is a finite volume method. Due to the direct modeling for the time evolution solution of the interface radiative intensity, a smooth transition of the transport physics from optical thin to optical thick can be accurately recovered. Many numerical examples are included to validate the current approach.« less

  3. Fiber optic sensor for monitoring a density of road traffic

    NASA Astrophysics Data System (ADS)

    Nedoma, Jan; Fajkus, Marcel; Martinek, Radek; Mec, Pavel; Novak, Martin; Jargus, Jan; Vasinek, Vladimir

    2017-10-01

    Authors of this article have focused on the use of fiber-optic technology in the car traffic. The article describes the use of fiber-optic interferometer for the purpose of the dynamic calculation of traffic density and inclusion the vehicle into the traffic lane. The objective is to increase safety and traffic flow. Presented solution is characterized by the non-destructive character to the road - sensor no need built into the roadway. The sensor works with standard telecommunications fibers of the G.652 standard. Other hallmarks are immunity to electromagnetic interference (EMI) and passivity of concerning the power supply. The massive expansion of optical cables within telecommunication needs along roads offers the possibility of connecting to the existing telecommunications fiber-optic network without a converter. Information can be transmitted at distances of several km up to tens km by this fiber-optic network. Set of experimental measurements in real traffic flow verified the functionality of presented solution.

  4. Electronic structure and optical properties of CdSxSe1-x solid solution nanostructures from X-ray absorption near edge structure, X-ray excited optical luminescence, and density functional theory investigations

    NASA Astrophysics Data System (ADS)

    Murphy, M. W.; Yiu, Y. M.; Ward, M. J.; Liu, L.; Hu, Y.; Zapien, J. A.; Liu, Yingkai; Sham, T. K.

    2014-11-01

    The electronic structure and optical properties of a series of iso-electronic and iso-structural CdSxSe1-x solid solution nanostructures have been investigated using X-ray absorption near edge structure, extended X-ray absorption fine structure, and X-ray excited optical luminescence at various absorption edges of Cd, S, and Se. It is found that the system exhibits compositions, with variable local structure in-between that of CdS and CdSe accompanied by tunable optical band gap between that of CdS and CdSe. Theoretical calculation using density functional theory has been carried out to elucidate the observations. It is also found that luminescence induced by X-ray excitation shows new optical channels not observed previously with laser excitation. The implications of these observations are discussed.

  5. The light transmission and distribution in an optical fiber coated with TiO2 particles.

    PubMed

    Wang, Wen; Ku, Young

    2003-03-01

    The light delivery and distribution phenomena along the optical fiber coated with the P-25 TiO(2) particles by dipping was investigated. The surface properties (coverage, roughness and thickness) of the TiO(2) layer coated on the optical fiber were characterized by SEM micrographs. For TiO(2) layer prepared from solutions containing less than 20 wt.% of TiO(2) slurry, the thickness of layer was increased linearly with the TiO(2) slurry content in solutions. The UV light intensity transmitted along a TiO(2)-coated optical fiber decreased more rapidly than that transmitted along a non-coated fiber. Based on the experimental results, the light intensity distribution around a coated optical fiber was modeled to determine the optimum configuration for the design of optical fiber reactors under various operational conditions. Copyright 2002 Elsevier Science Ltd.

  6. Heterostructure of ferromagnetic and ferroelectric materials with magneto-optic and electro-optic effects

    NASA Technical Reports Server (NTRS)

    Zou, Yingyin Kevin (Inventor); Jiang, Hua (Inventor); Li, Kewen Kevin (Inventor); Guo, Xiaomei (Inventor)

    2012-01-01

    A heterostructure of multiferroics or magnetoelectrics (ME) was disclosed. The film has both ferromagnetic and ferroelectric properties, as well as magneto-optic (MO) and electro-optic (EO) properties. Oxide buffer layers were employed to allow grown a cracking-free heterostructure a solution coating method.

  7. Resolution study of imaging in nanoparticle optical phantoms

    NASA Astrophysics Data System (ADS)

    Ortiz-Rascón, E.; Bruce, N. C.; Flores-Flores, J. O.; Sato-Berru, R.

    2011-08-01

    We present results of resolution and optical characterization studies of silicon dioxide nanoparticle solutions. These phantoms consist of spherical particles with a mean controlled diameter of 168 and 429 nm. The importance of this work lies in using these solutions to develop phantoms with optical properties that closely match those of human breast tissue at near-IR wavelengths, and also to compare different resolution criteria for imaging studies at these wavelengths. Characterization involves illuminating the solution with a laser beam transmitted through a recipient of known width containing the solution. Resulting intensity profiles from the light spot are measured as function of the detector position. Measured intensity profiles were fitted to the calculated profiles obtained from diffusion theory, using the method of images. Fitting results give us the absorption and transport scattering coefficients. These coefficients can be modified by changing the particle concentration of the solution. We found that these coefficients are the same order of magnitude as those of human tissue reported in published studies. The resolution study involves measuring the edge response function (ERF) for a mask embedded on the nanoparticle solutions and fitting it to the calculated ERF, obtaining the resolution for the Hebden, Sparrow and Bentzen criteria.

  8. Optical Kerr Spatiotemporal Dark-Lump Dynamics of Hydrodynamic Origin

    NASA Astrophysics Data System (ADS)

    Baronio, Fabio; Wabnitz, Stefan; Kodama, Yuji

    2016-04-01

    There is considerable fundamental and applicative interest in obtaining nondiffractive and nondispersive spatiotemporal localized wave packets propagating in optical cubic nonlinear or Kerr media. Here, we analytically predict the existence of a novel family of spatiotemporal dark lump solitary wave solutions of the (2 +1 )D nonlinear Schrödinger equation. Dark lumps represent multidimensional holes of light on a continuous wave background. We analytically derive the dark lumps from the hydrodynamic exact soliton solutions of the (2 +1 )D shallow water Kadomtsev-Petviashvili model, inheriting their complex interaction properties. This finding opens a novel path for the excitation and control of optical spatiotemporal waveforms of hydrodynamic footprint and multidimensional optical extreme wave phenomena.

  9. Multiscale free-space optical interconnects for intrachip global communication: motivation, analysis, and experimental validation.

    PubMed

    McFadden, Michael J; Iqbal, Muzammil; Dillon, Thomas; Nair, Rohit; Gu, Tian; Prather, Dennis W; Haney, Michael W

    2006-09-01

    The use of optical interconnects for communication between points on a microchip is motivated by system-level interconnect modeling showing the saturation of metal wire capacity at the global layer. Free-space optical solutions are analyzed for intrachip communication at the global layer. A multiscale solution comprising microlenses, etched compound slope microprisms, and a curved mirror is shown to outperform a single-scale alternative. Microprisms are designed and fabricated and inserted into an optical setup apparatus to experimentally validate the concept. The multiscale free-space system is shown to have the potential to provide the bandwidth density and configuration flexibility required for global communication in future generations of microchips.

  10. Optical Kerr Spatiotemporal Dark-Lump Dynamics of Hydrodynamic Origin.

    PubMed

    Baronio, Fabio; Wabnitz, Stefan; Kodama, Yuji

    2016-04-29

    There is considerable fundamental and applicative interest in obtaining nondiffractive and nondispersive spatiotemporal localized wave packets propagating in optical cubic nonlinear or Kerr media. Here, we analytically predict the existence of a novel family of spatiotemporal dark lump solitary wave solutions of the (2+1)D nonlinear Schrödinger equation. Dark lumps represent multidimensional holes of light on a continuous wave background. We analytically derive the dark lumps from the hydrodynamic exact soliton solutions of the (2+1)D shallow water Kadomtsev-Petviashvili model, inheriting their complex interaction properties. This finding opens a novel path for the excitation and control of optical spatiotemporal waveforms of hydrodynamic footprint and multidimensional optical extreme wave phenomena.

  11. Ultra high-definition video: convergence toward 100Gbps and beyond for digital A/V connectivity with fiber optics

    NASA Astrophysics Data System (ADS)

    Parekh, Devang; Nguyen, Nguyen X.

    2018-02-01

    The recent advent of Ultra-high-definition television (also known as Ultra HD television, Ultra HD, UHDTV, UHD and Super Hi-Vision) has accelerated a demand for a Fiber-in-the-Premises video communication (VCOM) solution that converges toward 100Gbps and Beyond. Hybrid Active-Optical-Cables (AOC) is a holistic connectivity platform well suited for this "The Last Yard" connectivity; as it combines both copper and fiber optics to deliver a high data-rate and power transmission needed. While technically feasible yet challenging to manufacture, hybrid-AOC could be a holygrail fiber-optics solution that dwarfs the volume of both telecom and datacom connection in the foreseeable future.

  12. Front and pulse solutions for the complex Ginzburg-Landau equation with higher-order terms.

    PubMed

    Tian, Huiping; Li, Zhonghao; Tian, Jinping; Zhou, Guosheng

    2002-12-01

    We investigate one-dimensional complex Ginzburg-Landau equation with higher-order terms and discuss their influences on the multiplicity of solutions. An exact analytic front solution is presented. By stability analysis for the original partial differential equation, we derive its necessary stability condition for amplitude perturbations. This condition together with the exact front solution determine the region of parameter space where the uniformly translating front solution can exist. In addition, stable pulses, chaotic pulses, and attenuation pulses appear generally if the parameters are out of the range. Finally, applying these analysis into the optical transmission system numerically we find that the stable transmission of optical pulses can be achieved if the parameters are appropriately chosen.

  13. Freeform étendue-preserving optics for light and color mixing

    NASA Astrophysics Data System (ADS)

    Sorgato, Simone; Mohedano, Rubén.; Chaves, Julio; Cvetkovic, Aleksandra; Hernández, Maikel; Benítez, Pablo; Miñano, Juan C.; Thienpont, Hugo; Duerr, Fabian

    2015-09-01

    Today's SSL illumination market shows a clear trend towards high flux packages with higher efficiency and higher CRI, realized by means of multiple color chips and phosphors. Such light sources require the optics to provide both near- and far-field color mixing. This design problem is particularly challenging for collimated luminaries, since traditional diffusers cannot be employed without enlarging the exit aperture and reducing brightness (so increasing étendue). Furthermore, diffusers compromise the light output ratio (efficiency) of the lamps to which they are applied. A solution, based on Köhler integration, consisting of a spherical cap comprising spherical microlenses on both its interior and exterior sides was presented in 2012. When placed on top of an inhomogeneous multichip Lambertian LED, this so-called Shell-Mixer creates a homogeneous (both spatially and angularly) virtual source, also Lambertian, where the images of the chips merge. The virtual source is located at the same position with essentially the same size of the original source. The diameter of this optics was 3 times that of the chip-array footprint. In this work, we present a new version of the Shell-Mixer, based on the Edge Ray Principle, where neither the overall shape of the cap nor the surfaces of the lenses are constrained to spheres or rotational Cartesian ovals. This new Shell- Mixer is freeform, only twice as large as the original chip-array and equals the original model in terms of brightness, color uniformity and efficiency.

  14. Optical absorption and thermal stability study of Cu doped NiO nanoparticles

    NASA Astrophysics Data System (ADS)

    Varunkumar, K.; Ethiraj, Anita Sagadevan; Kechiantz, Ara

    2018-05-01

    This work reports variation of Cu doping concentration in NiO nanoparticles (NiO:Cu NPs) synthesized via chemical co-precipitation from solution by using NiCl2.6H2O as precursor, CuSO4.5H2O as dopant and NaOH as surfactant. We studied optical and thermal stability of prepared NiO:Cu NPs by UV-Vis absorbance, Diffuse Reflectance Spectroscopy (DRS), Atomic Absorption Spectroscopy (AAS), and Thermo Gravimetric/Differential Scanning Calorimetry (TGA/DSC) analyses. Optical absorption data of NiO:Cu NPs indicated strong absorption peaks shifted towards blue with respect to the peak of undoped NiO NPs due to quantum confinement effect. The bandgap estimated via Tauc plot first increased from 3.32eV (undoped NiO NPs) to 3.37 eV (8 at % of Cu in NiO NPs) and further increase of Cu doping to 10 at% reduced the bandgap to 3.35 eV. Such behavior of the bandgap clearly indicates that the size of NiO NPs first reduces with Cu doping up to 8 at % and then increases with further Cu doping to 10 at %. This behavior of reduction in particle size with increased doping can be attributed to the dislocation density and microstrain developed in NiO:Cu NPs. Thermal stability analysis demonstrated that in addition undoped NiO NPs, all NiO:Cu nanoparticle samples exhibited good thermal stability.

  15. In vivo microcirculation imaging of the sub surface fingertip using correlation mapping optical coherence tomography (cmOCT)

    NASA Astrophysics Data System (ADS)

    Dsouza, Roshan I.; Zam, Azhar; Subhash, Hrebesh M.; Larin, Kirill V.; Leahy, Martin

    2013-02-01

    We describe a novel application of correlation mapping optical coherence tomography (cmOCT) for sub-surface fingerprint biometric identification. Fingerprint biometrics including automated fingerprint identification systems, are commonly used to recognise the fingerprint, since they constitute simple, effective and valuable physical evidence. Spoofing of biometric fingerprint devices can be easily done because of the limited information obtained from the surface topography. In order to overcome this limitation a potentially more secure source of information is required for biometric identification applications. In this study, we retrieve the microcirculation map of the subsurface fingertip by use of the cmOCT technique. To increase probing depth of the sub surface microcirculation, an optical clearing agent composed of 75% glycerol in aqueous solution was applied topically and kept in contact for 15 min. OCT intensity images were acquired from commercial research grade swept source OCT system (model OCT1300SS, Thorlabs Inc. USA). A 3D OCT scan of the fingertip was acquired over an area of 5x5 mm using 1024x1024 A-scans in approximately 70 s. The resulting volume was then processed using the cmOCT technique with a 7x7 kernel to provide a microcirculation map. We believe these results will demonstrate an enhanced security level over artificial fingertips. To the best of our knowledge, this is the first demonstration of imaging microcirculation map of the subsurface fingertip.

  16. Longterm and spatial variability of Aerosol optical properties measured by sky radiometer in Japan sites

    NASA Astrophysics Data System (ADS)

    Aoki, K.

    2016-12-01

    Aerosols and cloud play an important role in the climate change. We started the long-term monitoring of aerosol and cloud optical properties since 1990's by using sky radiometer (POM-01, 02; Prede Co. Ltd., Japan). We provide the information, in this presentation, on the aerosol optical properties with respect to their temporal and spatial variability in Japan site (ex. Sapporo, Toyama, Kasuga and etc). The global distributions of aerosols have been derived from earth observation satellite and have been simulated in numerical models, which assume optical parameters. However, these distributions are difficult to derive because of variability in time and space. Therefore, Aerosol optical properties were investigated using the measurements from ground-based and ship-borne sky radiometer. The sky radiometer is an automatic instrument that takes observations only in daytime under the clear sky conditions. Observation of diffuse solar intensity interval was made every ten or five minutes by once. The aerosol optical properties were computed using the SKYRAD.pack version 4.2. The obtained Aerosol optical properties (Aerosol optical thickness, Ångström exponent, Single scattering albedo, and etc.) and size distribution volume clearly showed spatial and temporal variability in Japan area. In this study, we present the temporal and spatial variability of Aerosol optical properties at several Japan sites, applied to validation of satellite and numerical models. This project is validation satellite of GCOM-C, JAXA. The GCOM-C satellite scheduled to be launched in early 2017.

  17. Computer modeling of electromagnetic problems using the geometrical theory of diffraction

    NASA Technical Reports Server (NTRS)

    Burnside, W. D.

    1976-01-01

    Some applications of the geometrical theory of diffraction (GTD), a high frequency ray optical solution to electromagnetic problems, are presented. GTD extends geometric optics, which does not take into account the diffractions occurring at edges, vertices, and various other discontinuities. Diffraction solutions, analysis of basic structures, construction of more complex structures, and coupling using GTD are discussed.

  18. Modifying Optical Properties of ZnO Films by Forming Zn[subscript 1-x] Co[subscript x]O Solid Solutions via Spray Pyrolysis

    ERIC Educational Resources Information Center

    Bentley, Anne K.; Weaver, Gabriela C.; Russell, Cianan B.; Fornes, William L.; Choi, Kyoung-Shin; Shih, Susan M.

    2007-01-01

    A simple and cost-effective experiment for the development and characterization of semiconductors using Uv-vis spectroscopy is described. The study shows that the optical properties of ZnO films can be easily modified by forming Zn[subscript 1-x] Co[subscript x]O solid solutions via spray pyrolysis.

  19. Improved Optics For Quasi-Elastic Light Scattering

    NASA Technical Reports Server (NTRS)

    Cheung, Harry Michael

    1995-01-01

    Improved optical train devised for use in light-scattering measurements of quasi-elastic light scattering (QELS) and laser spectroscopy. Measurements performed on solutions, microemulsions, micellular solutions, and colloidal dispersions. Simultaneous measurements of total intensity and fluctuations in total intensity of light scattered from sample at various angles provides data used, in conjunction with diffusion coefficients, to compute sizes of particles in sample.

  20. Spatial-spectral flexible optical networking: enabling switching solutions for a simplified and efficient SDM network platform

    NASA Astrophysics Data System (ADS)

    Tomkos, I.; Zakynthinos, P.; Klonidis, D.; Marom, D.; Sygletos, S.; Ellis, A.; Salvadori, E.; Siracusa, D.; Angelou, M.; Papastergiou, G.; Psaila, N.; Ferran, J. F.; Ben-Ezra, S.; Jimenez, F.; Fernández-Palacios, J. P.

    2013-12-01

    The traffic carried by core optical networks grows at a steady but remarkable pace of 30-40% year-over-year. Optical transmissions and networking advancements continue to satisfy the traffic requirements by delivering the content over the network infrastructure in a cost and energy efficient manner. Such core optical networks serve the information traffic demands in a dynamic way, in response to requirements for shifting of traffics demands, both temporally (day/night) and spatially (business district/residential). However as we are approaching fundamental spectral efficiency limits of singlemode fibers, the scientific community is pursuing recently the development of an innovative, all-optical network architecture introducing the spatial degree of freedom when designing/operating future transport networks. Spacedivision- multiplexing through the use of bundled single mode fibers, and/or multi-core fibers and/or few-mode fibers can offer up to 100-fold capacity increase in future optical networks. The EU INSPACE project is working on the development of a complete spatial-spectral flexible optical networking solution, offering the network ultra-high capacity, flexibility and energy efficiency required to meet the challenges of delivering exponentially growing traffic demands in the internet over the next twenty years. In this paper we will present the motivation and main research activities of the INSPACE consortium towards the realization of the overall project solution.

  1. Potency of sensor displacement detection of cholesterol concentration using flat mirror as media for learning waves and optics

    NASA Astrophysics Data System (ADS)

    Budiyanto, M.; Suhariningsih; Yasin, M.

    2018-04-01

    The use of instructional media needs to be implemented in one of the courses such as wave and optics to cover up the contents of material. To bring this advantage, one of the alternatives that can be used is to use fiber optic sensors for detecting cholesterol concentration. This device brings about the concepts of how the wave and optics behaves and operates. In doing so, the variation concentration of cholesterol solution is 0 ppm, 50 ppm, 100 ppm, 150 ppm, 200 ppm, 250 ppm, and 300 ppm. The work mechanism of cholesterol concentration detection is laser propagation of He-Ne wavelength 632.5 nm through fiber optic in cholesterol solution and reflected back by flat mirror then ray reflected through fiber optic bundle so detected by SL-818 silicon detector in the form of voltage Output. The detection results showed that the maximum output voltage showed a linear decrease in the concentration of cholesterol solution with a sensitivity of 0.21 mV/ppm and linearity of more than 95%. In terms of developed learning media, the use of optical fiber sensor learning media is compatible with optical wave learning in terms of basic competence of lectures, learning indicators, learning materials, student worksheets and science process skills. From the assessment of validation of learning media obtained an assessment of more than 95%. The results of this study indicate the parameters and performance of sensors that have accurate potential as a medium for learning wave and optics.

  2. Naturally inspired SERS substrates fabricated by photocatalytically depositing silver nanoparticles on cicada wings

    PubMed Central

    2014-01-01

    Densely stacked Ag nanoparticles with an average diameter of 199 nm were effectively deposited on TiO2-coated cicada wings (Ag/TiO2-coated wings) from a water-ethanol solution of AgNO3 using ultraviolet light irradiation at room temperature. It was seen that the surfaces of bare cicada wings contained nanopillar array structures. In the optical absorption spectra of the Ag/TiO2-coated wings, the absorption peak due to the localized surface plasmon resonance (LSPR) of Ag nanoparticles was observed at 440 nm. Strong Surface-enhanced Raman scattering (SERS) signals of Rhodamine 6G adsorbed on the Ag/TiO2-coated wings were clearly observed using the 514.5-nm line of an Ar+ laser. The Ag/TiO2-coated wings can be a promising candidate for naturally inspired SERS substrates. PMID:24959110

  3. Naturally inspired SERS substrates fabricated by photocatalytically depositing silver nanoparticles on cicada wings

    NASA Astrophysics Data System (ADS)

    Tanahashi, Ichiro; Harada, Yoshiyuki

    2014-06-01

    Densely stacked Ag nanoparticles with an average diameter of 199 nm were effectively deposited on TiO2-coated cicada wings (Ag/TiO2-coated wings) from a water-ethanol solution of AgNO3 using ultraviolet light irradiation at room temperature. It was seen that the surfaces of bare cicada wings contained nanopillar array structures. In the optical absorption spectra of the Ag/TiO2-coated wings, the absorption peak due to the localized surface plasmon resonance (LSPR) of Ag nanoparticles was observed at 440 nm. Strong Surface-enhanced Raman scattering (SERS) signals of Rhodamine 6G adsorbed on the Ag/TiO2-coated wings were clearly observed using the 514.5-nm line of an Ar+ laser. The Ag/TiO2-coated wings can be a promising candidate for naturally inspired SERS substrates.

  4. Design and testing of an endoscopic photoacoustic probe for determination of treatment depth after photodynamic therapy

    NASA Astrophysics Data System (ADS)

    Viator, John A.; Paltauf, Guenther; Jacques, Steven L.; Prahl, Scott A.

    2001-06-01

    An endoscopic photoacoustic probe is designed and tested for use in PDT treatment of esophageal cancer. The probe, measuring less than 2.5 mm in diameter, was designed to fit within the lumen of an endoscope that will be inserted into an esophagus after PDT. PDT treatment results in a blanched, necrotic layer of cancerous tissue over a healthy, deeper layer of perfused tissue. The photoacoustic probe was designed to use acoustic propagation time to determine the thickness of the blanched surface of the esophagus, which corresponds to treatment depth. A side-firing 600 micrometers fiber delivered 532 nm laser light to induce acoustic waves in the perfused layer of the esophagus beneath the blanched (treated) layer. A PVDF transducer detected the induced acoustic waves and transmitted the signal to an oscilloscope. The probe was tested on clear and turbid tissue phantom layers over an optically absorbing dye solution.

  5. Enhancement of porous silicon photoluminescence property by lithium chloride treatment

    NASA Astrophysics Data System (ADS)

    Azaiez, Khawla; Zaghouani, Rabia Benabderrahmane; Khamlich, Saleh; Meddeb, Hosny; Dimassi, Wissem

    2018-05-01

    Porous silicon (PS) decorated by several nanostructured metal elements has still aroused interests as promising composites in many industrial applications. With the focus mainly on the synthesis, the aspect of stability against optical irradiation of such materials has so far not been thoroughly addressed. This work focuses primarily on the influence of lithium chloride solution (LiCl) treatment on the physical properties of PS. Variations in the structural and optoelectronic properties of PS were observed after immersion in (LiCl), as revealed by the obtained analyses. Moreover, enhanced photoluminescence (PL) property of the PS after passivation by lithium particles was clearly shown, and their presence on the surface of the microporous silicon was confirmed by FTIR spectroscopy and atomic force microscopy. An improvement of the minority carrier lifetime was also obtained, which was attributed to the decrease of the surface recombination velocity after LiCl treatment.

  6. Nanoemulsion-based delivery systems for polyunsaturated (ω-3) oils: formation using a spontaneous emulsification method.

    PubMed

    Gulotta, Alessandro; Saberi, Amir Hossein; Nicoli, Maria Cristina; McClements, David Julian

    2014-02-19

    Nanoemulsion-based delivery systems are finding increasing utilization to encapsulate lipophilic bioactive components in food, personal care, cosmetic, and pharmaceutical applications. In this study, a spontaneous emulsification method was used to fabricate nanoemulsions from polyunsaturated (ω-3) oils, that is, fish oil. This low-energy method relies on formation of fine oil droplets when an oil/surfactant mixture is added to an aqueous solution. The influence of surfactant-to-oil ratio (SOR), oil composition (lemon oil and MCT), and cosolvent composition (glycerol, ethanol, propylene glycol, and water) on the formation and stability of the systems was determined. Optically transparent nanoemulsions could be formed by controlling SOR, oil composition, and aqueous phase composition. The spontaneous emulsification method therefore has considerable potential for fabricating nanoemulsion-based delivery systems for incorporating polyunsatured oils into clear food, personal care, and pharmaceutical products.

  7. Surface Stabilized InP/GaP/ZnS Quantum Dots with Mg Ions for WLED Application.

    PubMed

    Park, Joong Pill; Kim, Sang-Wook

    2016-05-01

    One of the most highlighted cadmium-free quantum dots (QDs), InP-based QDs, have improved their optical properties. However, InP-based QDs have some practical drawbacks, for example, stability, compared with CdSe-based QDs. Poor stability of InP-based QDs yields critical problems, such as agglomeration and photoluminescence quenching in light emitting diode (LED). It has to be solved for applications and most research has focused on thick outer shells as an effective solution. We introduced magnesium cations for improving stability of InP-based QDs. We applied very small amounts of Mg cations as surface stabilizers, as a result, stability of QDs is clearly improved. Then, QD based LED chips also yield improved values including RA of 84.4, CCT of 3799 K, and luminous efficiency of 129.57 Im/W, which are highly improved data compared with our previous results.

  8. Graphene-based carbon-layered electrode array technology for neural imaging and optogenetic applications

    PubMed Central

    Park, Dong-Wook; Schendel, Amelia A.; Mikael, Solomon; Brodnick, Sarah K.; Richner, Thomas J.; Ness, Jared P.; Hayat, Mohammed R.; Atry, Farid; Frye, Seth T.; Pashaie, Ramin; Thongpang, Sanitta; Ma, Zhenqiang; Williams, Justin C.

    2014-01-01

    Neural micro-electrode arrays that are transparent over a broad wavelength spectrum from ultraviolet to infrared could allow for simultaneous electrophysiology and optical imaging, as well as optogenetic modulation of the underlying brain tissue. The long-term biocompatibility and reliability of neural micro-electrodes also require their mechanical flexibility and compliance with soft tissues. Here we present a graphene-based, carbon-layered electrode array (CLEAR) device, which can be implanted on the brain surface in rodents for high-resolution neurophysiological recording. We characterize optical transparency of the device at >90% transmission over the ultraviolet to infrared spectrum and demonstrate its utility through optical interface experiments that use this broad spectrum transparency. These include optogenetic activation of focal cortical areas directly beneath electrodes, in vivo imaging of the cortical vasculature via fluorescence microscopy and 3D optical coherence tomography. This study demonstrates an array of interfacing abilities of the CLEAR device and its utility for neural applications. PMID:25327513

  9. Particle image velocimetry measurements in an anatomical vascular model fabricated using inkjet 3D printing

    NASA Astrophysics Data System (ADS)

    Aycock, Kenneth I.; Hariharan, Prasanna; Craven, Brent A.

    2017-11-01

    For decades, the study of biomedical fluid dynamics using optical flow visualization and measurement techniques has been limited by the inability to fabricate transparent physical models that realistically replicate the complex morphology of biological lumens. In this study, we present an approach for producing optically transparent anatomical models that are suitable for particle image velocimetry (PIV) using a common 3D inkjet printing process (PolyJet) and stock resin (VeroClear). By matching the index of refraction of the VeroClear material using a room-temperature mixture of water, sodium iodide, and glycerol, and by printing the part in an orientation such that the flat, optical surfaces are at an approximately 45° angle to the build plane, we overcome the challenges associated with using this 3D printing technique for PIV. Here, we summarize our methodology and demonstrate the process and the resultant PIV measurements of flow in an optically transparent anatomical model of the human inferior vena cava.

  10. Optical properties of MgF2 nano-composite films dispersed with noble metal nanoparticles synthesized by sol-gel method

    NASA Astrophysics Data System (ADS)

    Wakaki, Moriaki; Soujima, Nobuaki; Shibuya, Takehisa

    2015-03-01

    Porous MgF2 films synthesized by a sol-gel method exhibit the lowest refractive index among the dielectric optical materials and are the most useful materials for the anti-reflection coatings. On the other hand, surface plasmon resonance (SPR) absorptions of noble metal nanoparticles in various solid matrices have been extensively studied. New functional materials like a SERS (Surface Enhanced Raman Spectroscopy) tips are expected by synthesizing composite materials between porous MgF2 films featured by the network of MgF2 nanoparticles and noble metal nanoparticles introduced within the network. In this study, fundamental physical properties including morphology and optical properties are characterized for these materials to make clear the potential of the composite system. Composite materials of MgF2 films dispersed with noble metal (Ag, Au) nanoparticles were prepared using the sol-gel technique with various annealing temperatures and densities of noble metal nanoparticles. The structural morphology was analyzed by an X-ray diffractometer (XRD) and a scanning electron microscope (SEM). The size and shape distributions of the metal nanoparticles were observed using a transmission electron microscope (TEM). The optical properties of fabricated composite films were characterized by UV-Vis-NIR and FT-IR spectrophotometers. The absorption spectra due to the surface plasmon resonance (SPR) of the metal nanoparticles were analyzed using the dielectric function considering the effective medium approximation, typically Maxwell-Garnett model. The Raman scattering spectra were also studied to check the enhancement effect of specimen dropped on the MgF2: Ag nano-composite films deposited on Si substrate. Enhancement of the Raman intensity of pyridine solution specimen was observed.

  11. Evaluation of structural and optical properties of Ce3+ ions doped (PVA/PVP) composite films for new organic semiconductors

    NASA Astrophysics Data System (ADS)

    Ali, F. M.; Kershi, R. M.; Sayed, M. A.; AbouDeif, Y. M.

    2018-06-01

    Polymer blend films based on Polyvinyl alcohol (PVA)/Poly(vinylpyrrolidone) (PVP) doped with different concentration of cerium ions [(PVA/PVP)-x wt.% Ce3+] (x = 3%, 5%, 10% and 15%) were prepared by the conventional solution casting technique. The characteristics of the prepared polymer composite films were studied using X-ray diffraction (XRD), FT-IR and UV-Vis. spectroscopy. The XRD patterns of the investigated samples revealed a clear reduction on the structural parameters such as crystallinity degree and cluster size D of the doped PVA/PVP blend films compared with the virgin one whereas there is no big difference in the d spacing of the product composite films. Significant changes in FT-IR spectra are observed which reveal an interactions between the cerium ions and PVA/PVP blends. The absorption spectra in the ultraviolet-visible region showed a wide red shift in the fundamental absorption edge of (PVA/PVP)-x wt. % Ce3+ composites. The optical gap Eg gradually decreased from 4.54 eV for the undoped PVA/PVP film to 3.10 eV by increasing Ce3+ ions content. The optical dispersion parameters have been analyzed according to Wemple-Didomenico single oscillator model. The dispersion energy Ed, the single oscillator energy Eo, the average inter-band oscillator wavelength λo and the static refractive index no are strongly affected by cerium ions doping. Cerium ions incorporation in PVA/PVP blend films leads to a significant increase in the refractive index and decrease in the optical gap. These results are likely of great important in varieties of applications including polymer waveguides, organic semiconductors, polymer solar cells and optoelectronics devices.

  12. Propagation of evanescent waves in multimode chalcogenide fiber immersed in an aqueous acetone solution: theory and experiment

    NASA Astrophysics Data System (ADS)

    Korsakova, S. V.; Romanova, E. A.; Velmuzhov, A. P.; Kotereva, T. V.; Sukhanov, M. V.; Shiryaev, V. S.

    2017-04-01

    Chalcogenide fibers are considered as a base for creation of a fiber-optical platform for the mid-IR evanescent wave spectroscopy. In this work, transmittance of a multimode fiber made of Ge26As17Se25Te32 glass, immersed into an aqueous acetone solution was measured in the range of wavelengths 5 - 9 microns at various concentrations of the solution. A theoretical approach based on electromagnetic theory of optical fibers has been applied for analysis of evanescent modes propagation in the fiber. Attenuation coefficients calculated for each HE1m evanescent mode increase with the mode radial order m. This effect can be used for optimisation of the fiber-optic sensing elements for the mid-IR spectroscopy.

  13. Optical and Piezoelectric Study of KNN Solid Solutions Co-Doped with La-Mn and Eu-Fe.

    PubMed

    Peña-Jiménez, Jesús-Alejandro; González, Federico; López-Juárez, Rigoberto; Hernández-Alcántara, José-Manuel; Camarillo, Enrique; Murrieta-Sánchez, Héctor; Pardo, Lorena; Villafuerte-Castrejón, María-Elena

    2016-09-28

    The solid-state method was used to synthesize single phase potassium-sodium niobate (KNN) co-doped with the La 3+ -Mn 4+ and Eu 3+ -Fe 3+ ion pairs. Structural determination of all studied solid solutions was accomplished by XRD and Rietveld refinement method. Electron paramagnetic resonance (EPR) studies were performed to determine the oxidation state of paramagnetic centers. Optical spectroscopy measurements, excitation, emission and decay lifetime were carried out for each solid solution. The present study reveals that doping KNN with La 3+ -Mn 4+ and Eu 3+ -Fe 3+ at concentrations of 0.5 mol % and 1 mol %, respectively, improves the ferroelectric and piezoelectric behavior and induce the generation of optical properties in the material for potential applications.

  14. Optical and Piezoelectric Study of KNN Solid Solutions Co-Doped with La-Mn and Eu-Fe

    PubMed Central

    Peña-Jiménez, Jesús-Alejandro; González, Federico; López-Juárez, Rigoberto; Hernández-Alcántara, José-Manuel; Camarillo, Enrique; Murrieta-Sánchez, Héctor; Pardo, Lorena; Villafuerte-Castrejón, María-Elena

    2016-01-01

    The solid-state method was used to synthesize single phase potassium-sodium niobate (KNN) co-doped with the La3+–Mn4+ and Eu3+–Fe3+ ion pairs. Structural determination of all studied solid solutions was accomplished by XRD and Rietveld refinement method. Electron paramagnetic resonance (EPR) studies were performed to determine the oxidation state of paramagnetic centers. Optical spectroscopy measurements, excitation, emission and decay lifetime were carried out for each solid solution. The present study reveals that doping KNN with La3+–Mn4+ and Eu3+–Fe3+ at concentrations of 0.5 mol % and 1 mol %, respectively, improves the ferroelectric and piezoelectric behavior and induce the generation of optical properties in the material for potential applications. PMID:28773925

  15. Investigations of dark, bright, combined dark-bright optical and other soliton solutions in the complex cubic nonlinear Schrödinger equation with δ-potential

    NASA Astrophysics Data System (ADS)

    Baskonus, Haci Mehmet; Sulaiman, Tukur Abdulkadir; Bulut, Hasan; Aktürk, Tolga

    2018-03-01

    In this study, using the extended sinh-Gordon equation expansion method, we construct the dark, bright, combined dark-bright optical, singular, combined singular solitons and singular periodic waves solutions to the complex cubic nonlinear Schrödinger equation with δ-potential. The conditions for the existence of the obtained solutions are given. To present the physical feature of the acquired result, the 2D and 3D graphs are plotted under the choice of suitable values of the parameters.

  16. Optical quasi-soliton solutions for higher-order nonlinear Schrödinger equation with variable coefficients

    NASA Astrophysics Data System (ADS)

    Zhang, Jiefang; Yang, Qin; Dai, Chaoqing

    2005-04-01

    Optical quasi-soliton solutions for higher-order nonlinear Schrödinger equation (HNLS) with variable coefficients are considered. Based on the extended tanh-function method, we successfully obtained bright and dark quasi-soliton solutions under certain parametric conditions. We conclude that the parameter k(z) is unnecessary to be zero compared with [R. Yang et al., Opt. Commun. 242 (2004) 285]. Furthermore, we choose appropriate optical fiber parameters D2(z) and D3(z) to control the velocity of quasi-soliton and time shift, and discuss the evolution behavior of the special quasi-soliton. For D3(z) = α(z) = f(z) = 0, that is to say, under the absence of the higher order terms, we give same results as early reported in [R.Y. Hao, L. Li, Z.H. Li, W.R. Xue, G.S. Zhou, Opt. Commun. 236 (2004) 79]. As discussed examples, we also analyze three optical systems with real physical significance and obtain results which can be recovered in earlier papers.

  17. High Spectral Resolution Lidar Data

    DOE Data Explorer

    Eloranta, Ed

    2004-12-01

    The HSRL provided calibrated vertical profiles of optical depth, backscatter cross section and depoloarization at a wavelength of 532 nm. Profiles were acquired at 2.5 second intervals with 7.5 meter resolution. Profiles extended from an altitude of 100 m to 30 km in clear air. The lidar penetrated to a maximum optical depth of ~ 4 under cloudy conditions. Our data contributed directly to the aims of the M-PACE experiment, providing calibrated optical depth and optical backscatter measurements which were not available from any other instrument.

  18. Monitoring flood extent and area through multi-sensor, multi-temporal remote sensing: the Strymonas (Greece) river flood

    NASA Astrophysics Data System (ADS)

    Refice, Alberto; Tijani, Khalid; Lovergine, Francesco P.; D'Addabbo, Annarita; Nutricato, Raffaele; Morea, Alberto

    2017-04-01

    Satellite monitoring of flood events at high spatial and temporal resolution is considered a difficult problem, mainly due to the lack of data with sufficient acquisition frequency and timeliness. The problem is worsened by the typically cloudy weather conditions associated to floods, which obstacle the propagation of e.m. waves in the optical spectral range, forbidding acquisitions by optical sensors. This problem is not present for longer wavelengths, so that radar imaging sensors are recognized as viable solutions for long-term flood monitoring. In selected cases, however, weather conditions may remain clear for sufficient amounts of time, enabling monitoring of the evolution of flood events through long time series of satellite images, both optical and radar. In this contribution, we present a case study of long-term integrated monitoring of a flood event which affected part of the Strymonas river basin, a transboundary river with source in Bulgaria, which flows then through Greece up to the Aegean Sea. The event, which affected the floodplain close to the river mouth, started at the beginning of April 2015, due to heavy rain, and lasted for several months, with some water pools still present at the beginning of September. Due to the arid climate characterizing the area, weather conditions were cloud-free for most of the period covering the event. We collected one high-resolution, X-band, COSMO-SkyMed, 5 C-band, Sentinel-1 SAR images, and 11 optical Landsat-8 images of the area. SAR images were calibrated, speckle-filtered and precisely geocoded; optical images were radiometrically corrected to obtain ground reflectance values from which NDVI maps were derived. The images were then thresholded to obtain binary flood maps for each day. Threshold values for microwave and optical data were calibrated by comparing one SAR and one optical image acquired on the same date. Results allow to draw a multi-temporal map of the flood evolution with high temporal resolution. The extension of flooded area can also be tracked in time, allowing to envisage testing of evapotranspiration/absorption models.

  19. A Classroom Demonstration of Rayleigh Light Scattering in Optically Active and Inactive Systems.

    ERIC Educational Resources Information Center

    Pecina, Monica Avalos; Smith, Charles A.

    1999-01-01

    Argues that the concept of optical activity is vague to students because it is difficult for instructors to demonstrate the phenomenon in the classroom. Presents a demonstration that allows students to observe and manipulate the optical path of polarized light through optically inactive and active solutions. (CCM)

  20. Influence of optical activity on rogue waves propagating in chiral optical fibers.

    PubMed

    Temgoua, D D Estelle; Kofane, T C

    2016-06-01

    We derive the nonlinear Schrödinger (NLS) equation in chiral optical fiber with right- and left-hand nonlinear polarization. We use the similarity transformation to reduce the generalized chiral NLS equation to the higher-order integrable Hirota equation. We present the first- and second-order rational solutions of the chiral NLS equation with variable and constant coefficients, based on the modified Darboux transformation method. For some specific set of parameters, the features of chiral optical rogue waves are analyzed from analytical results, showing the influence of optical activity on waves. We also generate the exact solutions of the two-component coupled nonlinear Schrödinger equations, which describe optical activity effects on the propagation of rogue waves, and their properties in linear and nonlinear coupling cases are investigated. The condition of modulation instability of the background reveals the existence of vector rogue waves and the number of stable and unstable branches. Controllability of chiral optical rogue waves is examined by numerical simulations and may bring potential applications in optical fibers and in many other physical systems.

  1. Light fidelity (Li-Fi): towards all-optical networking

    NASA Astrophysics Data System (ADS)

    Tsonev, Dobroslav; Videv, Stefan; Haas, Harald

    2013-12-01

    Motivated by the looming radio frequency (RF) spectrum crisis, this paper aims at demonstrating that optical wireless communication (OWC) has now reached a state where it can demonstrate that it is a viable and matured solution to this fundamental problem. In particular, for indoor communications where most mobile data traffic is consumed, light fidelity (Li-Fi) which is related to visible light communication (VLC) offers many key advantages, and effective solutions to the issues that have been posed in the last decade. This paper discusses all key component technologies required to realize optical cellular communication systems referred to here as optical attocell networks. Optical attocells are the next step in the progression towards ever smaller cells, a progression which is known to be the most significant contributor to the improvements in network spectral efficiencies in RF wireless networks.

  2. Aplanatic telescopes based on Schwarzschild optical configuration: from grazing incidence Wolter-like x-ray optics to Cherenkov two-mirror normal incidence telescopes

    NASA Astrophysics Data System (ADS)

    Sironi, Giorgia

    2017-09-01

    At the beginning of XX century Karl Schwarzschild defined a method to design large-field aplanatic telescopes based on the use of two aspheric mirrors. The approach was then refined by Couder (1926) who, in order to correct for the astigmatic aberration, introduced a curvature of the focal plane. By the way, the realization of normal-incidence telescopes implementing the Schwarzschild aplanatic configuration has been historically limited by the lack of technological solutions to manufacture and test aspheric mirrors. On the other hand, the Schwarzschild solution was recovered for the realization of coma-free X-ray grazing incidence optics. Wolter-like grazing incidence systems are indeed free of spherical aberration, but still suffer from coma and higher order aberrations degrading the imaging capability for off-axis sources. The application of the Schwarzschild's solution to X-ray optics allowed Wolter to define an optical system that exactly obeys the Abbe sine condition, eliminating coma completely. Therefore these systems are named Wolter-Schwarzschild telescopes and have been used to implement wide-field X-ray telescopes like the ROSAT WFC and the SOHO X-ray telescope. Starting from this approach, a new class of X-ray optical system was proposed by Burrows, Burg and Giacconi assuming polynomials numerically optimized to get a flat field of view response and applied by Conconi to the wide field x-ray telescope (WFXT) design. The Schwarzschild-Couder solution has been recently re-discovered for the application to normal-incidence Cherenkov telescopes, thanks to the suggestion by Vassiliev and collaborators. The Italian Institute for Astrophysics (INAF) realized the first Cherenkov telescope based on the polynomial variation of the Schwarzschild configuration (the so-called ASTRI telescope). Its optical qualification was successfully completed in 2016, demonstrating the suitability of the Schwarzschild-like configuration for the Cherenkov astronomy requirements. Moreover, other Cherenkov telescopes based on Schwarzschild-Couder solutions are currently being completed at Fred Lawrence Whipple Observatory in southern Arizona, USA and at the Observatoire de Paris-Meudon. In this paper we will review the Karl Schwarzschild solution and its application to grazing incidence and Cherenkov telescopes, discussing on future applications in the field of high-energy astronomy.

  3. Nanodiamond in Colloidal Suspension: Electrophoresis; Other Observations

    NASA Technical Reports Server (NTRS)

    Meshik, A. P.; Pravdivtseva, O. V.; Hohenberg, C. M.

    2002-01-01

    Selective laser extraction has demonstrated that meteoritic diamonds may consist of subpopulations with different optical absorption properties, but it is not clear what makes them optically different. More work is needed to understand the mechanism for selective laser extraction. Additional information is contained in the original extended abstract.

  4. Aerosol optical depth under "clear" sky conditions derived from sea surface reflection of lidar signals.

    PubMed

    He, Min; Hu, Yongxiang; Huang, Jian Ping; Stamnes, Knut

    2016-12-26

    There are considerable demands for accurate atmospheric correction of satellite observations of the sea surface or subsurface signal. Surface and sub-surface reflection under "clear" atmospheric conditions can be used to study atmospheric correction for the simplest possible situation. Here "clear" sky means a cloud-free atmosphere with sufficiently small aerosol particles. The "clear" aerosol concept is defined according to the spectral dependence of the scattering cross section on particle size. A 5-year combined CALIPSO and AMSR-E data set was used to derive the aerosol optical depth (AOD) from the lidar signal reflected from the sea surface. Compared with the traditional lidar-retrieved AOD, which relies on lidar backscattering measurements and an assumed lidar ratio, the AOD retrieved through the surface reflectance method depends on both scattering and absorption because it is based on two-way attenuation of the lidar signal transmitted to and then reflected from the surface. The results show that the clear sky AOD derived from the surface signal agrees with the clear sky AOD available in the CALIPSO level 2 database in the westerly wind belt located in the southern hemisphere, but yields significantly higher aerosol loadings in the tropics and in the northern hemisphere.

  5. Approximate Solution Methods for Spectral Radiative Transfer in High Refractive Index Layers

    NASA Technical Reports Server (NTRS)

    Siegel, R.; Spuckler, C. M.

    1994-01-01

    Some ceramic materials for high temperature applications are partially transparent for radiative transfer. The refractive indices of these materials can be substantially greater than one which influences internal radiative emission and reflections. Heat transfer behavior of single and laminated layers has been obtained in the literature by numerical solutions of the radiative transfer equations coupled with heat conduction and heating at the boundaries by convection and radiation. Two-flux and diffusion methods are investigated here to obtain approximate solutions using a simpler formulation than required for exact numerical solutions. Isotropic scattering is included. The two-flux method for a single layer yields excellent results for gray and two band spectral calculations. The diffusion method yields a good approximation for spectral behavior in laminated multiple layers if the overall optical thickness is larger than about ten. A hybrid spectral model is developed using the two-flux method in the optically thin bands, and radiative diffusion in bands that are optically thick.

  6. Visualization of ex vivo human ciliated epithelium and induced flow using optical coherence tomography (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Ling, Yuye; Gamm, Uta A.; Yao, Xinwen; Arteaga-Solis, Emilio; Emala, Charles W.; Choma, Michael A.; Hendon, Christine P.

    2017-04-01

    The ciliated epithelium is important to the human respiratory system because it clears mucus that contains harmful microorganisms and particulate matter. We report the ex vivo visualization of human trachea/bronchi ciliated epithelium and induced flow characterized by using spectral-domain optical coherence tomography (SD-OCT). A total number of 17 samples from 7 patients were imaged. Samples were obtained from Columbia University Department of Anesthesiology's tissue bank. After excision, the samples were placed in Gibco Medium 199 solution with oxygen at 4°C until imaging. The samples were maintained at 36.7°C throughout the experiment. The imaging protocol included obtaining 3D volumes and 200 consecutive B-scans parallel to the head-to-feet direction (superior-inferior axis) of the airway, using Thorlabs Telesto system at 1300 nm at 28 kHz A-line rate and a custom built high resolution SDOCT system at 800nm at 32 kHz A-line rate. After imaging, samples were processed with H and E histology. Speckle variance of the time resolved datasets demonstrate significant contrast at the ciliated epithelium sites. Flow images were also obtained after injecting 10μm polyester beads into the solution, which shows beads traveling trajectories near the ciliated epithelium areas. In contrary, flow images taken in the orthogonal plane show no beads traveling trajectories. This observation is in line with our expectation that cilia drive flow predominantly along the superior-inferior axis. We also observed the protective function of the mucus, shielding the epithelium from the invasion of foreign objects such as microspheres. Further studies will be focused on the cilia's physiological response to environmental changes such as drug administration and physical injury.

  7. Three-dimensional (3D) evaluation of liquid distribution in shake flask using an optical fluorescence technique.

    PubMed

    Azizan, Amizon; Büchs, Jochen

    2017-01-01

    Biotechnological development in shake flask necessitates vital engineering parameters e.g. volumetric power input, mixing time, gas liquid mass transfer coefficient, hydromechanical stress and effective shear rate. Determination and optimization of these parameters through experiments are labor-intensive and time-consuming. Computational Fluid Dynamics (CFD) provides the ability to predict and validate these parameters in bioprocess engineering. This work provides ample experimental data which are easily accessible for future validations to represent the hydrodynamics of the fluid flow in the shake flask. A non-invasive measuring technique using an optical fluorescence method was developed for shake flasks containing a fluorescent solution with a waterlike viscosity at varying filling volume (V L  = 15 to 40 mL) and shaking frequency ( n  = 150 to 450 rpm) at a constant shaking diameter (d o  = 25 mm). The method detected the leading edge (LB) and tail of the rotating bulk liquid (TB) relative to the direction of the centrifugal acceleration at varying circumferential heights from the base of the shake flask. The determined LB and TB points were translated into three-dimensional (3D) circumferential liquid distribution plots. The maximum liquid height (H max ) of the bulk liquid increased with increasing filling volume and shaking frequency of the shaking flask, as expected. The toroidal shapes of LB and TB are clearly asymmetrical and the measured TB differed by the elongation of the liquid particularly towards the torus part of the shake flask. The 3D liquid distribution data collected at varying filling volume and shaking frequency, comprising of LB and TB values relative to the direction of the centrifugal acceleration are essential for validating future numerical solutions using CFD to predict vital engineering parameters in shake flask.

  8. Second harmonic generation imaging of skeletal muscle tissue and myofibrils

    NASA Astrophysics Data System (ADS)

    Campagnola, Paul J.; Mohler, William H.; Plotnikov, Sergey; Millard, Andrew C.

    2006-02-01

    Second Harmonic Generation (SHG) imaging microscopy is used to examine the morphology and structural properties of intact muscle tissue. Using biochemical and optical analysis, we characterize the molecular structure underlying SHG from the complex muscle sarcomere. We find that SHG from isolated myofibrils is abolished by extraction of myosin, but is unaffected by removal or addition of actin filaments. We thus determined that the SHG emission arises from domains of the sarcomere containing thick filaments. By fitting the SHG polarization anisotropy to theoretical response curves, we find an orientation for the harmonophore that corresponds well to the pitch angle of the myosin rod α-helix with respect to the thick filament axis. Taken together, these data indicate that myosin rod domains are the key structures giving rise to SHG from striated muscle. Using SHG imaging microscopy, we have also examined the effect of optical clearing with glycerol to achieve greater penetration into specimens of skeletal muscle tissue. We find that treatment with 50% glycerol results in a 2.5 fold increase in achievable SHG imaging depth. Fast Fourier Transform (FFT) analysis shows quantitatively that the periodicity of the sarcomere structure is unaltered by the clearing process. Also, comparison of the SHG angular polarization dependence shows no change in the supramolecular organization of acto-myosin complexes. We suggest that the primary mechanism of optical clearing in muscle with glycerol treatment results from the reduction of cytoplasmic protein concentration and concomitant decrease in the secondary inner filter effect on the SHG signal. The pronounced lack of dependence of glycerol concentration on the imaging depth indicates that refractive index matching plays only a minor role in the optical clearing of muscle.

  9. An entropy maximization problem related to optical communication

    NASA Technical Reports Server (NTRS)

    Mceliece, R. J.; Rodemich, E. R.; Swanson, L.

    1986-01-01

    In relation to a problem in optical communication, the paper considers the general problem of maximizing the entropy of a stationary radom process that is subject to an average transition cost constraint. By using a recent result of Justesen and Hoholdt, an exact solution to the problem is presented and a class of finite state encoders that give a good approximation to the exact solution is suggested.

  10. Study of large nonlinear change phase in Hibiscus Sabdariffa

    NASA Astrophysics Data System (ADS)

    Trejo-Durán, M.; Alvarado-Méndez, E.; Andrade-Lucio, J. A.; Rojas-Laguna, R.; Vázquez-Guevara, M. A.

    2015-09-01

    High intensities electromagnetic energy interacting with organic media gives rise to nonlinear optical effects. Hibiscus Sabdariffa is a flower whose concentrated solution presents interesting nonlinear optical properties. This organic material shows an important self-phase modulation with changes bigger than 2π. We present a diffraction ring patterns study of the Hibiscus Sabdariffa solution. Numerical results of transmittance, with refraction and simultaneous absorption, are shown.

  11. Fabrication and performance analysis of a high-coupling-efficiency and convenient-integration optical transceiver

    NASA Astrophysics Data System (ADS)

    He, Hui-min; Liu, Feng-man; Xue, Hai-yun; Wu, Peng; Song, Man-gu; Sun, Yu; Cao, Li-qiang

    2017-07-01

    An optical transceiver with a novel optical subassembly structure is proposed in this paper, which achieves high coupling efficiency and low assembly difficulty. The proposed optical transceiver consumes 0.9 W power and retains a small size of 28 mm×16 mm×3 mm. The fabrication process of the silicon substrate and the assembly process of the optical transceiver are demonstrated in details. Moreover, the optical transceiver is measured in order to verify its transmission performance. The clear eye diagrams and the low bit error rate ( BER) less than 10-13 at 10 Gbit/s per channel show good transmission characteristics of the designed optical transceiver.

  12. OCT analysis of microneedle and Er:YAG surface ablation for enhanced transdermal delivery of hyperosmotic agents for optical skin clearing

    NASA Astrophysics Data System (ADS)

    Stumpp, Oliver F.; Welch, A. J.; Gill, Harvinder S.; Prausnitz, Mark R.

    2004-07-01

    The purpose of this study is to investigate the feasibility of using microneedles in comparison to Er:YAG skin surface laser ablation as a means to modify the epidermis of in-vitro hamster skin to facilitate delivery of topically applied hyper-osmotics such as glycerol into the skin to achieve optical skin clearing. This allows to temporarily reduce scattering of light in otherwise turbid tissues with potential applications pertaining to non-invasive optical imaging techniques such as optical coherence tomography (OCT) or therapeutic applications like laser blood vessel coagulation to treat port wine stains in skin. A portable, battery powered Er:YAG laser (Lasette) manufactured by Cell Robotics Inc. was used to produce holes in the stratum corneum and epidermis using individual 400 μs pulses causing localized ablation. Following each laser pulse the tissue was mechanically translated by 1 mm before another pulse was delivered. As an alternative method to the use of an expensive laser source requiring some kind of light scanning mechanism to treat larger skin areas efficiently, microneedles were investigated. They do not require an energy supply, are also pain-free and can be manufactured into arrays allowing treatment of larger skin areas. A single application forms micron scale holes in the stratum corneum through which topically applied skin clearing agents such as glycerol can penetrate into the tissue. In this feasibility study individual microneedles were used to manually induce holes in the skin each spaced approximately 1 mm apart from the other. Upon such epidermal modification by either technique, glycerol was then applied to the tissue surface and amplitude OCT measurements monitored changes of the optical properties of the tissue over time. Due to the geometry of the microneedle used in this study the cross sectional area of each hole in the epidermis was about 68% smaller than the comparable ablation site caused by an individual laser pulse. Results indicate enhanced skin clearing rates due to the induced holes in the stratum corneum in both cases by a factor of 5 to 8. Due to the larger area of laser ablation in comparison to the holes caused by microneedles, overall skin clearing rates are higher with the laser. However, localized data analysis near holes produced by either technique yields comparable results which show an increase in the clearing rate of up to 10 to 13 times over intact skin without any holes.

  13. Catheter for Cleaning Surgical Optics During Surgical Procedures: A Possible Solution for Residue Buildup and Fogging in Video Surgery.

    PubMed

    de Abreu, Igor Renato Louro Bruno; Abrão, Fernando Conrado; Silva, Alessandra Rodrigues; Corrêa, Larissa Teresa Cirera; Younes, Riad Nain

    2015-05-01

    Currently, there is a tendency to perform surgical procedures via laparoscopic or thoracoscopic access. However, even with the impressive technological advancement in surgical materials, such as improvement in quality of monitors, light sources, and optical fibers, surgeons have to face simple problems that can greatly hinder surgery by video. One is the formation of "fog" or residue buildup on the lens, causing decreased visibility. Intracavitary techniques for cleaning surgical optics and preventing fog formation have been described; however, some of these techniques employ the use of expensive and complex devices designed solely for this purpose. Moreover, these techniques allow the cleaning of surgical optics when they becomes dirty, which does not prevent the accumulation of residue in the optics. To solve this problem we have designed a device that allows cleaning the optics with no surgical stops and prevents the fogging and residue accumulation. The objective of this study is to evaluate through experimental testing the effectiveness of a simple device that prevents the accumulation of residue and fogging of optics used in surgical procedures performed through thoracoscopic or laparoscopic access. Ex-vivo experiments were performed simulating the conditions of residue presence in surgical optics during a video surgery. The experiment consists in immersing the optics and catheter set connected to the IV line with crystalloid solution in three types of materials: blood, blood plus fat solution, and 200 mL of distilled water and 1 vial of methylene blue. The optics coupled to the device were immersed in 200 mL of each type of residue, repeating each immersion 10 times for each distinct residue for both thirty and zero degrees optics, totaling 420 experiments. A success rate of 98.1% was observed after the experiments, in these cases the device was able to clean and prevent the residue accumulation in the optics.

  14. A noble refractive optical scanner with linear response

    NASA Astrophysics Data System (ADS)

    Mega, Yair J.; Lai, Zhenhua; DiMarzio, Charles A.

    2013-03-01

    Many applications in various fields of science and engineering use steered optical beam systems. Currently, many methods utilize mirrors in order to steer the beam. However, this approach is an off-axis solution, which normally increases the total size of the system as well as its error and complexity. Other methods use a "Risely Prisms" based solution, which is on-axis solution, however it poses some difficulties from an engineering standpoint, and therefore isn't widely used. We present here a novel technique for steering a beam on its optical axis with a linear deflection response. We derived the formulation for the profile required of the refractive optical component necessary for preforming the beam steering. The functionality of the device was simulated analytically using Matlab, as well as using a ray-tracing software, Zemax, and showed agreement with the analytical model. An optical element was manufactured based on the proposed design and the device was tested. The results show agreement with our hypothesis. We also present some proposed geometries of the several other devices, all based on the same concept, which can be used for higher performance applications such as two-dimensional scanner, video rate scanner etc.

  15. Preliminary analyses of WL experiment No. 701, space environment effects on operating fiber optic systems

    NASA Technical Reports Server (NTRS)

    Taylor, E. W.; Berry, J. N.; Sanchez, A. D.; Padden, R. J.; Chapman, S. P.

    1992-01-01

    A brief overview of the analyses performed to date on WL Experiment-701 is presented. Four active digital fiber optic links were directly exposed to the space environment for a period of 2114 days. The links were situated aboard the Long Duration Exposure Facility (LDEF) with the cabled, single fiber windings atop an experimental tray containing instrumentation for exercising the experiment in orbit. Despite the unplanned and prolonged exposure to trapped and galactic radiation, wide temperature extremes, atomic oxygen interactions, and micro-meteorite and debris impacts, in most instances the optical data links performed well within the experimental limits. Analysis of the recorded orbital data clearly indicates that fiber optic applications in space will meet with success. Ongoing tests and analysis of the experiment at the Phillips Laboratory's Optoelectronics Laboratory will expand this premise, and establish the first known and extensive database of active fiber optic link performance during prolonged space exposure. WL Exp-701 was designed as a feasibility demonstration for fiber optic technology in space applications, and to study the performance of operating fiber systems exposed to space environmental factors such as galactic radiation, and wide temperature cycling. WL Exp-701 is widely acknowledged as a benchmark accomplishment that clearly demonstrates, for the first time, that fiber optic technology can be successfully used in a variety of space applications.

  16. Polymer optical fiber grating as water activity sensor

    NASA Astrophysics Data System (ADS)

    Zhang, Wei; Webb, David J.

    2014-05-01

    Controlling the water content within a product has long been required in the chemical processing, agriculture, food storage, paper manufacturing, semiconductor, pharmaceutical and fuel industries. The limitations of water content measurement as an indicator of safety and quality are attributed to differences in the strength with which water associates with other components in the product. Water activity indicates how tightly water is "bound," structurally or chemically, in products. Water absorption introduces changes in the volume and refractive index of poly(methyl methacrylate) PMMA. Therefore for a grating made in PMMA based optical fiber, its wavelength is an indicator of water absorption and PMMA thus can be used as a water activity sensor. In this work we have investigated the performance of a PMMA based optical fiber grating as a water activity sensor in sugar solution, saline solution and Jet A-1 aviation fuel. Samples of sugar solution with sugar concentration from 0 to 8%, saline solution with concentration from 0 to 22%, and dried (10ppm), ambient (39ppm) and wet (68ppm) aviation fuels were used in experiments. The corresponding water activities are measured as 1.0 to 0.99 for sugar solution, 1.0 to 0.86 for saline solution, and 0.15, 0.57 and 1.0 for the aviation fuel samples. The water content in the measured samples ranges from 100% (pure water) to 10 ppm (dried aviation fuel). The PMMA based optical fiber grating exhibits good sensitivity and consistent response, and Bragg wavelength shifts as large as 3.4 nm when the sensor is transferred from dry fuel to wet fuel.

  17. Optical clearing of vaginal tissues

    NASA Astrophysics Data System (ADS)

    Chang, Chun-Hung; Myers, Erinn M.; Kennelly, Michael J.; Fried, Nathaniel M.

    2017-02-01

    Near-IR laser energy in conjunction with applied tissue cooling is being investigated for thermal remodeling of endopelvic fascia during minimally invasive treatment of female stress urinary incontinence. Previous simulations of light transport, heat transfer, and tissue thermal damage have shown that a transvaginal approach is more feasible than a transurethral approach. However, undesirable thermal insult to vaginal wall was predicted. This study explores whether an optical clearing agent (OCA) can improve optical penetration depth and completely preserve vaginal wall during subsurface treatment of endopelvic fascia. Several OCA mixtures were tested, and 100% glycerol was found to be optimal. Optical transmission studies, optical coherence tomography, reflection spectroscopy, and computer simulations of thermal damage to tissue using glycerol were performed. The OCA produced a 61% increase in optical transmission through porcine vaginal wall at 37 °C after 30 min. Monte Carlo (MC) light transport, heat transfer, and Arrhenius integral thermal damage simulations were performed. MC model showed improved energy deposition in endopelvic fascia using OCA. Without OCA, 62, 37, and 1% of energy was deposited in vaginal wall, endopelvic fascia, and urethral wall, compared with 50, 49, and 1% with OCA. Use of OCA also yielded 0.5 mm increase in treatment depth, allowing potential thermal tissue remodeling at 3 mm depth.

  18. Long arc orbit determination for Mariner 9 using combined radio and optical data types

    NASA Technical Reports Server (NTRS)

    Born, G. H.; Mohan, S. N.

    1974-01-01

    Results of postflight orbit determination for the Mariner 9 trajectory (Mariner-Mars 1971 mission) using Doppler data combined with optical data in the form of TV photographs of the natural satellites and Mars' surface features. It is shown that the combined data yield a solution which is a factor of 3 to 5 better than that obtained from Doppler-only solutions for the node of the orbit relative to the plane perpendicular to the Earth-Mars line. Consequently, these optical data types have a demonstrated potential to significantly improve planetary orbiter navigation accuracies.

  19. Study of nonlinear refraction of organic dye by Z-scan technique using He-Ne laser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Medhekar, S.; Kumar, R.; Mukherjee, S.

    2013-02-05

    Laser induced third-order nonlinear optical responses of Brilliant Green solution has been investigated by utilizing single beam Z-scan technique with a continuous-wave He-Ne laser radiation at 632.8 nm. It was observed that the material exhibits self-defocusing type optical nonlinearity. The measurements of nonlinear refraction were carried out at different dye concentrations and found that the increase in solution concentration leads to the linear increase of the nonlinear refractive index. The experimental results confirm great potential of the Brilliant Green for the application in nonlinear optical devices.

  20. Exhaustive Strategy for Optical Survey of Geosynchronous Region using TAROT Telescopes

    NASA Astrophysics Data System (ADS)

    Richard, P.; Yanez, C.; Morand, V.; Verzeni, A.; Boer, M.; Klotz, A.

    CNES and CNRS has been working on Optical Space Surveillance and Tracking for many years using the TAROT telescopes network. The goal of the study presented here is to propose an exhaustive strategy for optical survey of geosynchronous region. First, constraints will be defined on perigee and apogee of the orbits for which we are looking for exhaustiveness and then solutions will be explored making the survey in one or several nights using one or several telescopes. The last part of the study proposes solutions to help maintaining exhaustiveness if some observations failed.

  1. A general solution for the registration of optical multispectral scanners

    NASA Technical Reports Server (NTRS)

    Rader, M. L.

    1974-01-01

    The paper documents a general theory for registration (mapping) of data sets gathered by optical scanners such as the ERTS satellite MSS and the Skylab S-192 MSS. This solution is generally applicable to scanners which have rotating optics. Navigation data and ground control points are used in a statistically weighted adjustment based on a mathematical model of the dynamics of the spacecraft and the scanner system. This adjustment is very similar to the well known photogrammetric adjustments used in aerial mapping. Actual tests have been completed on NASA aircraft 24 channel MSS data, and the results are very encouraging.

  2. Development of carbon dioxide laser doppler instrumentation detection of clear air turbulence

    NASA Technical Reports Server (NTRS)

    Sonnenschein, C.; Jelalian, A.; Keene, W.

    1970-01-01

    The analytical, experimental, and developmental aspects of an airborne, pulsed, carbon dioxide laser-optical radar system are described. The laser detects clear air turbulence and performs Doppler measurements of this air-motion phenomenon. Conclusions and recommendations arising from the development of the laser system are presented.

  3. Plant Histology: Clearing and the Optical Section.

    ERIC Educational Resources Information Center

    Freeman, H. E.

    1985-01-01

    Clearing is a simple and rapid technique in which 75 percent lactic acid is used to remove pigments and cytoplasmic contents of fresh leaves, enabling microscopic view of various internal leaf layers. Procedures for using the technique (which helps students gain a more thorough understanding of plant anatomy) are given. (DH)

  4. Generation of higher-order rogue waves from multibreathers by double degeneracy in an optical fiber.

    PubMed

    Wang, Lihong; He, Jingsong; Xu, Hui; Wang, Ji; Porsezian, Kuppuswamy

    2017-04-01

    In this paper, we construct a special kind of breather solution of the nonlinear Schrödinger (NLS) equation, the so-called breather-positon (b-positon for short), which can be obtained by taking the limit λ_{j}→λ_{1} of the Lax pair eigenvalues in the order-n periodic solution, which is generated by the n-fold Darboux transformation from a special "seed" solution-plane wave. Further, an order-n b-positon gives an order-n rogue wave under a limit λ_{1}→λ_{0}. Here, λ_{0} is a special eigenvalue in a breather of the NLS equation such that its period goes to infinity. Several analytical plots of order-2 breather confirm visually this double degeneration. The last limit in this double degeneration can be realized approximately in an optical fiber governed by the NLS equation, in which an injected initial ideal pulse is created by a frequency comb system and a programable optical filter (wave shaper) according to the profile of an analytical form of the b-positon at a certain position z_{0}. We also suggest a new way to observe higher-order rogue waves generation in an optical fiber, namely, measure the patterns at the central region of the higher-order b-positon generated by above ideal initial pulses when λ_{1} is very close to the λ_{0}. The excellent agreement between the numerical solutions generated from initial ideal inputs with a low signal-to-noise ratio and analytical solutions of order-2 b-positon supports strongly this way in a realistic optical fiber system. Our results also show the validity of the generating mechanism of a higher-order rogue waves from a multibreathers through the double degeneration.

  5. Assessing the Penetrating Abilities of Experimental Preparation with Dental Infiltrant Features Using Optical Microscope: Preliminary Study.

    PubMed

    Skucha-Nowak, Małgorzata; Machorowska-Pieniążek, Agnieszka; Tanasiewicz, Marta

    2016-01-01

    The aim of the infiltration technique is to penetrate demineralized enamel with a low viscosity resin. Icon® (DMG) is the first ever and so far the only dental infiltrant. Bacteriostaticity is one of the properties that should be inherent in dental infiltrants, but Icon lacks this feature. The aim of the preliminary study was to properly choose a dye which would allow us to assess the penetrating abilities of our own, experimental preparation with features of a dental infiltrant with bacteriostatic properties and to compare using an optical microscope the depth of infiltration of the designed experimental preparation with the infiltrant available on the market. The preparation is supposed to infiltrate decalcified human enamel and be assessed with an optical microscope. Eosin, neutral fuchsine and methylene blue were added to experimental preparation with dental infiltrant features and to Icon® (DMG) in order to assess the depth of penetration of the experimental solution into the decalcified layers of enamel. The experimental solution mixes well with eosin, neutral fuchsine, and methylene blue. During the preliminary study, the authors concluded that the experimental solution mixes well with methylene blue, neutral fuchsine, and eosin. An addition of eosin to a preparation which infiltrates inner, demineralized enamel layers, facilitates the assessment of such a preparation with an optical microscope. A designed experimental solution with the main ingredients, i.e., 2-hydroxyethyl methacrylate (HEMA) and tetraethylene glycol dimethacrylate (TEGDMA) with a ratio of 75% to 25% penetrates the demineralized (decalcified) inner parts of the enamel and polymerizes when exposed to light. In order to assess the infiltration of the experimental solution into the demineralized enamel layers, it is required to improve the measurement techniques that utilize optical microscopy.

  6. The high squareness Sm-Co magnet having Hcb=10.6 kOe at 150°C

    NASA Astrophysics Data System (ADS)

    Machida, Hiroaki; Fujiwara, Teruhiko; Kamada, Risako; Morimoto, Yuji; Takezawa, Masaaki

    2017-05-01

    The relationship between magnetic properties and magnetic domain structures of Sm(Fe, Cu, Zr, Co)7.5 magnet was investigated. The developed Sm-Co magnet, which is conducted homogenization heat treatment at ingot state, high temperature short time sintering and long time solid solution heat treatment showed the maximum energy product, [BH]m of 34.0 MGOe and the coercivity, Hcb of 11.3 kOe at 20°C respectively. Moreover, Hcb of 10.6 kOe at 150°C was achieved. Heat treated ingot has clear 1-7 phase in mother phase from optical microscope observation. Kerr effect microscope with magnetic field applied was used to investigate magnetic domain structure. Reverse magnetic domains were generated evenly but generation of them from inside grain were not observed. Cell structure was observed by scanning transmission electron microscope and composition analysis was conducted by energy dispersive X-ray spectroscopy. Cell size was approximately 150 ˜ 300 nm, Fe and Cu were clearly separated and concentrated to 2-17 phase and 1-5 phase respectively. Moreover, Cu concentration went up to 40 at% in 1-5 phase. That means the gap of domain wall energy between 1-5 phase and 2-17 phase was increased due to microstructure control by conducting heat treatment for compositional homogeneity.

  7. Arsenic sulfide layers for dielectric reflection mirrors prepared from solution

    NASA Astrophysics Data System (ADS)

    Matějec, Vlastimil; Pedlikova, Jitka; BartoÅ, Ivo; Podrazký, Ondřej

    2017-12-01

    Chalcogenide materials due to high refractive indices, transparency in the mid-IR spectral region, nonlinear refractive indices, etc, have been employed as fibers and films in different photonic devices such as light amplifiers, optical regenerators, broadband radiation sources. Chalcogenide films can be prepared by physical methods as well as by solution-based techniques in which solutions of chalcogenides in amines are used. This paper presents results on the solution-based fabrication and optical characterization of single arsenic sulfide layers and multilayer stacks containing As2S3 layers together with porous silica layers coated on planar and fiber-optic substrates. Input As2S3 solutions for the layer fabrications were prepared by dissolving As2S3 powder in n-propylamine in a concentration of 0.50 mol/l. These solutions were applied on glass slides by dip-coating method and obtained layers were thermally treated in vacuum at temperatures up to 180 °C. Similar procedure was used for As2S3 layers in multilayer stacks. Such stacks were fabricated by repeating the application of one porous silica layer prepared by the sol-gel method and one As2S3 layer onto glass slides or silica fibers (a diameter of 0.3 mm) by using the dip-coating method. It has been found that the curing process of the applied layers has to be carefully controlled in order to obtain stacks with three pairs of such layers. Single arsenic and porous silica layers were characterized by optical microscopy, and by measuring their transmission spectra in a range of 200-2500 nm. Thicknesses and refractive indices were estimated from the spectra. Transmission spectra of planar multilayer stacks were measured, too. Interference bands have been determined from optical measurements on the multilayer stacks with a minimum transmittance of about 50% which indicates the possibility of using such stacks as reflecting mirrors.

  8. Third-order nonlinear optical properties of phthalocyanines in solution and in polystyrene films

    NASA Astrophysics Data System (ADS)

    Reeves, Roger J.; Powell, Richard C.; Chang, Young H.; Ford, Warren T.; Zhu, Weiming

    1996-01-01

    Degenerate four-wave mixing (DFWM) measurements of third-order nonlinear optical (NLO) coefficients of metal-free, Cu, Pt, Pb and Bi octa(2-ethylhexyloxy) phthalocyanines (MPc's) were done with 20 ps duration laser pulses under resonant conditions at 532 nm in polystyrene films and under nonresonant conditions at 1064 nm in chloroform solutions. The NLO coefficients ξxxxx(3) show saturation with increasing incident intensity and no strong dependence on the central metal atom of the MPc below the saturation intensity. Optical delays of the probe-pulse up to 3 ns show an acoustic phonon response in both the polystyrene films and the chloroform solutions. An intensity-dependent absorption coefficient was measured by a pump/probe experiment and used in a simple model to qualitatively account for the saturation of ξ(3) measured by DFWM.

  9. Birefringence control of solution-cast film of cellulose triacetate

    NASA Astrophysics Data System (ADS)

    Kiyama, Ayumi; Nobukawa, Shogo; Yamaguchi, Masayuki

    2017-10-01

    We controlled the optical anisotropy of a solution-cast film composed of cellulose triacetate (CTA) by adding ferrocene. Owing to the molecular orientation in the film plane of solution-cast films, which results from the normal stress applied during the solvent evaporation process, the average refractive index is usually higher in the plane of the film than in the thickness direction. We found that the addition of ferrocene, which is miscible with CTA, reduced the optical anisotropy by nematic interaction; i.e., ferrocene molecules are forcibly embedded into the film plane accompanying the CTA chains. Because the direction of anisotropic polarizability of ferrocene is perpendicular to the long axis of the molecule, the refractive index in the thickness direction is reduced. Furthermore, the stress-optical coefficient in the glassy state is reduced by the addition of ferrocene.

  10. The effect of endodontic materials on the optical density of dyes used in marginal leakage studies.

    PubMed

    Kubo, Claudio Hideki; Valera, Marcia Carneiro; Gomes, Ana Paula Martins; Mancini, Maria Nadir Gasparoto; Camargo, Carlos Henrique Ribeiro

    2008-01-01

    The aim of this study was to determine the effect of the exposure of different endodontic materials to different dye solutions by evaluating the optical density of the dye solutions. Seventy-five plastic tubes were filled with one of the following materials: AH Plus, Sealapex, Portland cement, MTA (Angelus and Pro Root) and fifteen control plastic tubes were not. Each specimen of material and control was immersed in a container with 1 ml of each dye solution. A 0.1 ml-dye solution aliquote was removed before immersion and after 12, 24, 48 and 72 hours of each specimen immersion to record its optical density (OD) in a spectrophotometer. Statistical analysis was performed with ANOVA and Tukey tests (5%). No significant difference was found among any of the solution OD values for AH Plus cement. Portland cement promoted different OD values after 12 hours of immersion. MTA-Angelus cement presented different OD values only for 2% rhodamine B and the MTA-Pro Root cement presented different OD values in all 2% rhodamine B samples. Sealapex cement promoted a reduction in the India Ink OD values. Dye evaluation through OD seems to be an interesting method to select the best dye solution to use in a given marginal leakage study.

  11. PbS nanosculptured thin film for phase retarder, anti-reflective, excellent absorber, polarizer and sensor applications

    NASA Astrophysics Data System (ADS)

    Chaudhary, Ashok; Klebanov, Matvey; Abdulhalim, Ibrahim

    2015-11-01

    Lead-sulphide (PbS) nanosculptured thin film (nSTF) is prepared using a glancing angle deposition (GLAD) technique and the physical vapour deposition (PVD) process. The morphology of the GLAD films clearly shows that an anisotropic structure is obtained and is composed of micro-sheets with sharp top edges (a few tens of nanometres tip width). Due to this anisotropy, optical birefringence is induced in the nSTF as well as linear dichroism. The structural and optical properties of the PbS nSTF have been characterized by scanning electron microscopy, atomic force microscopy, Raman spectroscopy and transmission measurements. The Raman spectra of PbS nSTF exhibit sharp peaks representative of vibrations in nano-crystalline PbS. Due to the absorption of PbS the nSTF is found to act as a linear polarizer with good extinction and contrast in the near infra-red range. Due to its porosity this nSTF also has the ability to sense fluids, which we demonstrate using ethanol-water solution at different concentrations. The combination of these effects in PbS nSTF is believed to constitute a prime candidate for many desirable device applications in different aspects with the low cost of production in large areas.

  12. Photoabsorption of acridine yellow and proflavin bound to human serum albumin studied by means of quantum mechanics/molecular dynamics.

    PubMed

    Aidas, Kęstutis; Olsen, Jógvan Magnus H; Kongsted, Jacob; Ågren, Hans

    2013-02-21

    Attempting to unravel mechanisms in optical probing of proteins, we have performed pilot calculations of two cationic chromophores-acridine yellow and proflavin-located at different binding sites within human serum albumin, including the two primary drug binding sites as well as a heme binding site. The computational scheme adopted involves classical molecular dynamics simulations of the ligands bound to the protein and subsequent linear response polarizable embedding density functional theory calculations of the excitation energies. A polarizable embedding potential consisting of point charges fitted to reproduce the electrostatic potential and isotropic atomic polarizabilities computed individually for every residue of the protein was used in the linear response calculations. Comparing the calculated aqueous solution-to-protein shifts of maximum absorption energies to available experimental data, we concluded that the cationic proflavin chromophore is likely not to bind albumin at its drug binding site 1 nor at its heme binding site. Although agreement with experimental data could only be obtained in qualitative terms, our results clearly indicate that the difference in optical response of the two probes is due to deprotonation, and not, as earlier suggested, to different binding sites. The ramifications of this finding for design of molecular probes targeting albumin or other proteins is briefly discussed.

  13. Bioanalytical system for detection of cancer cells with photoluminescent ZnO nanorods

    NASA Astrophysics Data System (ADS)

    Viter, R.; Jekabsons, K.; Kalnina, Z.; Poletaev, N.; Hsu, S. H.; Riekstina, U.

    2016-11-01

    Using photoluminescent ZnO nanorods and carbohydrate marker SSEA-4, a novel cancer cell recognition system was developed. Immobilization of SSEA-4 antibodies (αSSEA-4) on ZnO nanorods was performed in buffer solution (pH = 7.1) over 2 h. The cancer cell line probes were fixed on the glass slide. One hundred microliters of ZnO-αSSEA-4 conjugates were deposited on the cell probe and exposed for 30 min. After washing photoluminescence spectra were recorded. Based on the developed methodology, ZnO-αSSEA-4 probes were tested on patient-derived breast and colorectal carcinoma cells. Our data clearly show that the carbohydrate SSEA-4 molecule is expressed on cancer cell lines and patient-derived cancer cells. Moreover, SSEA-4 targeted ZnO nanorods bind to the patient-derived cancer cells with high selectivity and the photoluminescence signal increased tremendously compared to the signal from the control samples. Furthermore, the photoluminescence intensity increase correlated with the extent of malignancy in the target cell population. A novel portable bioanalytical system, based on optical ZnO nanorods and fiber optic detection system was developed. We propose that carbohydrate SSEA-4 specific ZnO nanorods could be used for the development of cancer diagnostic biosensors and for targeted therapy.

  14. Simultaneous observation solutions for NASA-MOTS and SPEOPT station positions on the North American datum

    NASA Technical Reports Server (NTRS)

    Reece, J. S.; Marsh, J.

    1973-01-01

    Simultaneous observations of the GEOS-I and II flashing lamps by the NASA MOTS and SPEOPT cameras on the North American Datum (NAD) were analyzed using geometrical techniques to provide an adjustment of the station coordinates. Two separate adjustments were obtained. An optical data only solution was computed in which the solution scale was provided by the Rosman-Mojave distance obtained from a dynamic station solution. In a second adjustment, scaling was provided by processing simultaneous laser ranging data from Greenbelt and Wallops Island in a combined optical-laser solution. Comparisons of these results with previous GSFC dynamical solutions indicate an rms agreement on the order of 4 meters or better in each coordinate. Comparison with a detailed gravimetric geoid of North America yields agreement of 3 meters or better for mainland U.S. stations and 7 and 3 meters, respectively, for Bermuda and Puerto Rico.

  15. Breather management in the derivative nonlinear Schrödinger equation with variable coefficients

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhong, Wei-Ping, E-mail: zhongwp6@126.com; Texas A&M University at Qatar, P.O. Box 23874 Doha; Belić, Milivoj

    2015-04-15

    We investigate breather solutions of the generalized derivative nonlinear Schrödinger (DNLS) equation with variable coefficients, which is used in the description of femtosecond optical pulses in inhomogeneous media. The solutions are constructed by means of the similarity transformation, which reduces a particular form of the generalized DNLS equation into the standard one, with constant coefficients. Examples of bright and dark breathers of different orders, that ride on finite backgrounds and may be related to rogue waves, are presented. - Highlights: • Exact solutions of a generalized derivative NLS equation are obtained. • The solutions are produced by means of amore » transformation to the usual integrable equation. • The validity of the solutions is verified by comparing them to numerical counterparts. • Stability of the solutions is checked by means of direct simulations. • The model applies to the propagation of ultrashort pulses in optical media.« less

  16. Theory and Experiment Analysis of Two-Dimensional Acousto-Optic Interaction.

    DTIC Science & Technology

    1995-01-03

    The universal coupled wave equation of two dimensional acousto optic effect has been deduced and the solution of normal Raman-Hath acousto optic diffraction...was derived from it. The theory was compared with the experimental results of a two dimensional acousto optic device consisting of two one dimensional modulators. The experiment results agree with the theory. (AN)

  17. Coupling between magnetic and optical properties of stable Au-Fe solid solution nanoparticles

    NASA Astrophysics Data System (ADS)

    de Julián Fernández, C.; Mattei, G.; Paz, E.; Novak, R. L.; Cavigli, L.; Bogani, L.; Palomares, F. J.; Mazzoldi, P.; Caneschi, A.

    2010-04-01

    Au-Fe nanoparticles constitute one of the simplest prototypes of a multifunctional nanomaterial that can exhibit both magnetic and optical (plasmonic) properties. This solid solution, not feasible in the bulk phase diagram in thermal equilibrium, can be formed as a nanostructure by out-of-equilibrium processes. Here, the novel magnetic, optical and magneto-optical properties of ion-implanted Au-Fe solid solution nanoparticles dispersed in a SiO2 matrix are investigated and correlated. The surface plasmon resonance of the Au-Fe nanoparticles with almost equicomposition is strongly damped when compared to pure Au and to Au-rich Au-Fe nanoparticles. In all cases, the Au atoms are magnetically polarized, as measured by x-ray magnetic circular dichroism, and ferromagnetically coupled with Fe atoms. Although the chemical stability of Au-Fe nanoparticles is larger than that of Fe nanoparticles, both the magnetic moment per Fe atom and the order temperature are smaller. These results suggest that electronic and magnetic properties are more influenced by the hybridization of the electronic bands in the Au-Fe solid solution than by size effects. On the other hand, the magneto-optical transitions allowed in the vis-nIR spectral regions are very similar. In addition, we also observe, after studying the properties of thermally treated samples, that the Au-Fe alloy is stabilized, not by surface effects, but by the combination of the out-of-equilibrium nature of the ion implantation technique and by changes in the properties due to size effects.

  18. Coupling between magnetic and optical properties of stable Au-Fe solid solution nanoparticles.

    PubMed

    de Julián Fernández, C; Mattei, G; Paz, E; Novak, R L; Cavigli, L; Bogani, L; Palomares, F J; Mazzoldi, P; Caneschi, A

    2010-04-23

    Au-Fe nanoparticles constitute one of the simplest prototypes of a multifunctional nanomaterial that can exhibit both magnetic and optical (plasmonic) properties. This solid solution, not feasible in the bulk phase diagram in thermal equilibrium, can be formed as a nanostructure by out-of-equilibrium processes. Here, the novel magnetic, optical and magneto-optical properties of ion-implanted Au-Fe solid solution nanoparticles dispersed in a SiO(2) matrix are investigated and correlated. The surface plasmon resonance of the Au-Fe nanoparticles with almost equicomposition is strongly damped when compared to pure Au and to Au-rich Au-Fe nanoparticles. In all cases, the Au atoms are magnetically polarized, as measured by x-ray magnetic circular dichroism, and ferromagnetically coupled with Fe atoms. Although the chemical stability of Au-Fe nanoparticles is larger than that of Fe nanoparticles, both the magnetic moment per Fe atom and the order temperature are smaller. These results suggest that electronic and magnetic properties are more influenced by the hybridization of the electronic bands in the Au-Fe solid solution than by size effects. On the other hand, the magneto-optical transitions allowed in the vis-nIR spectral regions are very similar. In addition, we also observe, after studying the properties of thermally treated samples, that the Au-Fe alloy is stabilized, not by surface effects, but by the combination of the out-of-equilibrium nature of the ion implantation technique and by changes in the properties due to size effects.

  19. Quantitative optical imaging and sensing by joint design of point spread functions and estimation algorithms

    NASA Astrophysics Data System (ADS)

    Quirin, Sean Albert

    The joint application of tailored optical Point Spread Functions (PSF) and estimation methods is an important tool for designing quantitative imaging and sensing solutions. By enhancing the information transfer encoded by the optical waves into an image, matched post-processing algorithms are able to complete tasks with improved performance relative to conventional designs. In this thesis, new engineered PSF solutions with image processing algorithms are introduced and demonstrated for quantitative imaging using information-efficient signal processing tools and/or optical-efficient experimental implementations. The use of a 3D engineered PSF, the Double-Helix (DH-PSF), is applied as one solution for three-dimensional, super-resolution fluorescence microscopy. The DH-PSF is a tailored PSF which was engineered to have enhanced information transfer for the task of localizing point sources in three dimensions. Both an information- and optical-efficient implementation of the DH-PSF microscope are demonstrated here for the first time. This microscope is applied to image single-molecules and micro-tubules located within a biological sample. A joint imaging/axial-ranging modality is demonstrated for application to quantifying sources of extended transverse and axial extent. The proposed implementation has improved optical-efficiency relative to prior designs due to the use of serialized cycling through select engineered PSFs. This system is demonstrated for passive-ranging, extended Depth-of-Field imaging and digital refocusing of random objects under broadband illumination. Although the serialized engineered PSF solution is an improvement over prior designs for the joint imaging/passive-ranging modality, it requires the use of multiple PSFs---a potentially significant constraint. Therefore an alternative design is proposed, the Single-Helix PSF, where only one engineered PSF is necessary and the chromatic behavior of objects under broadband illumination provides the necessary information transfer. The matched estimation algorithms are introduced along with an optically-efficient experimental system to image and passively estimate the distance to a test object. An engineered PSF solution is proposed for improving the sensitivity of optical wave-front sensing using a Shack-Hartmann Wave-front Sensor (SHWFS). The performance limits of the classical SHWFS design are evaluated and the engineered PSF system design is demonstrated to enhance performance. This system is fabricated and the mechanism for additional information transfer is identified.

  20. Mobile Bay turbidity plume study

    NASA Technical Reports Server (NTRS)

    Crozier, G. F.

    1976-01-01

    Laboratory and field transmissometer studies on the effect of suspended particulate material upon the appearance of water are reported. Quantitative correlations were developed between remotely sensed image density, optical sea truth data, and actual sediment load. Evaluation of satellite image sea truth data for an offshore plume projects contours of transmissivity for two different tidal phases. Data clearly demonstrate the speed of change and movement of the optical plume for water patterns associated with the mouth of Mobile bay in which relatively clear Gulf of Mexico water enters the bay on the eastern side. Data show that wind stress in excess of 15 knots has a marked impact in producing suspended sediment loads.

  1. The Role of Optical Radiations in Skin Cancer

    PubMed Central

    Palla, Marco; Di Trolio, Rossella; Mozzillo, Nicola; Ascierto, Paolo A.

    2013-01-01

    Purpose. Electromagnetic radiation with wavelength in the range 100 nm to 1 mm is known as optical radiation and includes ultraviolet radiation, the visible spectrum, and infrared radiation. The deleterious short- and long-term biological effects of ultraviolet radiation, including melanoma and other skin cancers, are well recognized. Infrared radiation may also have damaging biological effects. Methods. The objective of this review was to assess the literature over the last 15 years and to summarize correlations between exposure to optical radiation and the risk of melanoma and other cancers. Results. There is a clear correlation between exposure to UV radiation and the development of skin cancer. Most importantly, a strong association between artificial UV radiation exposure, for example, tanning devices, and the risk of melanoma and squamous cell carcinoma has been clearly demonstrated. There is no clear evidence that exposure to IR and laser radiation may increase the risk of skin cancer, although negative health effects have been observed. Conclusions. Preventative strategies that involve provision of public information highlighting the risks associated with exposure to sunlight remain important. In addition, precautionary measures that discourage exposure to tanning appliances are required, as is legislation to prevent their use during childhood. PMID:23710365

  2. Optical neural net for classifying imaging spectrometer data

    NASA Technical Reports Server (NTRS)

    Barnard, Etienne; Casasent, David P.

    1989-01-01

    The problem of determining the composition of an unknown input mixture from its measured spectrum, given the spectra of a number of elements, is studied. The Hopfield minimization procedure was used to express the determination of the compositions as a problem suitable for solution by neural nets. A mathematical description of the problem was developed and used as a basis for a neural network solution and an optical implementation.

  3. Laser inhibited diffusion in rhodamine-ethanol solutions

    NASA Technical Reports Server (NTRS)

    Lawandy, N. M.; Fuhr, P. L.; Robinson, D. W.

    1981-01-01

    The diffusion of rhodamine-6G dye in ethanol is observed to be inhibited by optical pumping by a cadmium laser. The diffusion process is observed as a function of the solution temperature. The relative difference in diffusion coefficients with and without optical pumping is calculated. The effect is interpreted as being due to a stronger solvent-dye interaction in the first excited singlet state of rhodamine-6G.

  4. Image reconstruction

    NASA Astrophysics Data System (ADS)

    Vasilenko, Georgii Ivanovich; Taratorin, Aleksandr Markovich

    Linear, nonlinear, and iterative image-reconstruction (IR) algorithms are reviewed. Theoretical results are presented concerning controllable linear filters, the solution of ill-posed functional minimization problems, and the regularization of iterative IR algorithms. Attention is also given to the problem of superresolution and analytical spectrum continuation, the solution of the phase problem, and the reconstruction of images distorted by turbulence. IR in optical and optical-digital systems is discussed with emphasis on holographic techniques.

  5. Effect of solvents on optical band gap of silicon-doped graphene oxide

    NASA Astrophysics Data System (ADS)

    Tul Ain, Qura; Al-Modlej, Abeer; Alshammari, Abeer; Naeem Anjum, Muhammad

    2018-03-01

    The objective of this study was to determine the influence on the optical band gap when the same amount of silicon-doped graphene oxide was dissolved in three different solvents namely, distilled water, benzene, and dichloroethane. Ultraviolet-visible spectroscopy was used to analyse the optical properties of the solutions. Among all these solutions distilled water containing silicon-doped graphene oxide has the smallest optical band gap of 2.9 eV and is considered a semiconductor. Other solutions are not considered as semiconductors as they have optical band gaps greater than 4 eV. It was observed that there is an increase in the value of optical band gap of distilled water, benzene, and dichloroethane solutions indicating a rise in the insulating behaviour. In this experiment, graphene oxide was synthesised from graphite powder by modified Hummer’s method and was then doped with silicon. Synthesis and doping of graphene oxide were confirmed by various characterization techniques. Fourier transmission infrared spectroscopy was used for identification of surface functional groups. X-ray diffraction was carried out to confirm the formation of crystalline graphene oxide and silicon doped graphene oxide. In x-ray diffraction pattern, shifting of intensity peak from a 2θ value of 26.5° to 10° confirmed the synthesis of graphene oxide and various intensity peaks at different values of 2θ confirmed doping of graphene oxide with silicon. Scanning electron microscopy images indicated that graphene oxide sheets were decorated with spherical silicon nanoparticles. Energy dispersive x-ray spectroscopy showed that silicon doped graphene oxide powder contained 63.36% carbon, 34.05% oxygen, and 2.6% silicon.

  6. Single-image-based solution for optics temperature-dependent nonuniformity correction in an uncooled long-wave infrared camera.

    PubMed

    Cao, Yanpeng; Tisse, Christel-Loic

    2014-02-01

    In this Letter, we propose an efficient and accurate solution to remove temperature-dependent nonuniformity effects introduced by the imaging optics. This single-image-based approach computes optics-related fixed pattern noise (FPN) by fitting the derivatives of correction model to the gradient components, locally computed on an infrared image. A modified bilateral filtering algorithm is applied to local pixel output variations, so that the refined gradients are most likely caused by the nonuniformity associated with optics. The estimated bias field is subtracted from the raw infrared imagery to compensate the intensity variations caused by optics. The proposed method is fundamentally different from the existing nonuniformity correction (NUC) techniques developed for focal plane arrays (FPAs) and provides an essential image processing functionality to achieve completely shutterless NUC for uncooled long-wave infrared (LWIR) imaging systems.

  7. Optical characterization of synthetic faceted gem materials grown from hydrothermal solutions

    NASA Astrophysics Data System (ADS)

    Lu, Taijin; Shigley, James E.

    1998-10-01

    Various non-destructive optical characterization techniques have been used to characterize and identify synthetic gem materials grown from hydrothermal solutions, to include ruby, sapphire, emerald, amethyst and ametrine (amethyst-citrine), from their natural counterparts. The ability to observe internal features, such as inclusions, dislocations, twins, color bands, and growth zoning in gem materials is strongly dependent on the observation techniques and conditions, since faceted gemstones have many polished surfaces which can reflect and scatter light in various directions which can make observation difficult. However, diagnostic gemological properties of these faceted synthetic gem materials can be obtained by choosing effective optical characterization methods, and by modifying optical instruments. Examples of some of the distinctive features of synthetic amethyst, ametrine, pink quartz, ruby and emerald are presented to illustrate means of optical characterization of gemstones. The ability to observe defects by light scattering techniques is discussed.

  8. Infrared optical constants of H2O ice, amorphous nitric acid solutions, and nitric acid hydrates

    NASA Technical Reports Server (NTRS)

    Toon, Owen B.; Koehler, Birgit G.; Middlebrook, Ann M.; Tolbert, Margaret A.; Jordon, Joseph

    1994-01-01

    We determined the infrared optical constants of nitric acid trihydrate, nitric acid dihydrate, nitric acid monohydrate, and solid amorphous nitric acid solutions which crystallize to form these hydrates. We have also found the infrared optical constants of H2O ice. We measured the transmission of infrared light throught thin films of varying thickness over the frequency range from about 7000 to 500/cm at temperatures below 200 K. We developed a theory for the transmission of light through a substrate that has thin films on both sides. We used an iterative Kramers-Kronig technique to determine the optical constants which gave the best match between measured transmission spectra and those calculated for a variety of films of different thickness. These optical constants should be useful for calculations of the infrared spectrum of polar stratospheric clouds.

  9. EEG Dynamics Reflect the Distinct Cognitive Process of Optic Problem Solving

    PubMed Central

    She, Hsiao-Ching; Jung, Tzyy-Ping; Chou, Wen-Chi; Huang, Li-Yu; Wang, Chia-Yu; Lin, Guan-Yu

    2012-01-01

    This study explores the changes in electroencephalographic (EEG) activity associated with the performance of solving an optics maze problem. College students (N = 37) were instructed to construct three solutions to the optical maze in a Web-based learning environment, which required some knowledge of physics. The subjects put forth their best effort to minimize the number of convexes and mirrors needed to guide the image of an object from the entrance to the exit of the maze. This study examines EEG changes in different frequency bands accompanying varying demands on the cognitive process of providing solutions. Results showed that the mean power of θ, α1, α2, and β1 significantly increased as the number of convexes and mirrors used by the students decreased from solution 1 to 3. Moreover, the mean power of θ and α1 significantly increased when the participants constructed their personal optimal solution (the least total number of mirrors and lens used by students) compared to their non-personal optimal solution. In conclusion, the spectral power of frontal, frontal midline and posterior theta, posterior alpha, and temporal beta increased predominantly as the task demands and task performance increased. PMID:22815800

  10. From space qualified fiber optic gyroscope to generic fiber optic solutions available for space application

    NASA Astrophysics Data System (ADS)

    Buret, Thomas; Ramecourt, David; Napolitano, Fabien

    2017-11-01

    The aim of this article is to present how the qualification of the Fiber Optic Gyroscope technology from IXSEA has been achieved through the qualification of a large range of optical devices and related manufacturing processes. These qualified optical devices and processes, that are now fully mastered by IXSEA through vertical integration of the technology, can be used for other space optical sensors. The example of the SWARM project will be discussed.

  11. Optical smart card using semipassive communication.

    PubMed

    Glaser, I; Green, Shlomo; Dimkov, Ilan

    2006-03-15

    An optical secure short-range communication system is presented. The mobile unit (optical smart card) of this system utilizes a retroreflector with an optical modulator, using light from the stationary unit; this mobile unit has very low power consumption and can be as small as a credit card. Such optical smart cards offer better security than RF-based solutions, yet do not require physical contact. Results from a feasibility study model are included.

  12. Optical smart card using semipassive communication

    NASA Astrophysics Data System (ADS)

    Glaser, I.; Green, Shlomo; Dimkov, Ilan

    2006-03-01

    An optical secure short-range communication system is presented. The mobile unit (optical smart card) of this system utilizes a retroreflector with an optical modulator, using light from the stationary unit; this mobile unit has very low power consumption and can be as small as a credit card. Such optical smart cards offer better security than RF-based solutions, yet do not require physical contact. Results from a feasibility study model are included.

  13. Broadband optical limiting and nonlinear optical absorption properties of a novel hyperbranched conjugated polymer

    NASA Astrophysics Data System (ADS)

    Li, Chao; Liu, Chunling; Li, Quanshui; Gong, Qihuang

    2004-12-01

    The nonlinear transmittance of a novel hyperbranched conjugated polymer named DMA-HPV has been measured in CHCl 3 solution using a nanosecond optical parametric oscillator. DMA-HPV shows excellent optical limiting performance in the visible region from 490 to 610 nm. An explanation based on the combination of two-photon absorption and reverse saturable absorption was proposed for its huge and broadband nonlinear optical absorption.

  14. Biochemical component identification by plasmonic improved whispering gallery mode optical resonance based sensor

    NASA Astrophysics Data System (ADS)

    Saetchnikov, Vladimir A.; Tcherniavskaia, Elina A.; Saetchnikov, Anton V.; Schweiger, Gustav; Ostendorf, Andreas

    2014-05-01

    Experimental data on detection and identification of variety of biochemical agents, such as proteins, microelements, antibiotic of different generation etc. in both single and multi component solutions under varied in wide range concentration analyzed on the light scattering parameters of whispering gallery mode optical resonance based sensor are represented. Multiplexing on parameters and components has been realized using developed fluidic sensor cell with fixed in adhesive layer dielectric microspheres and data processing. Biochemical component identification has been performed by developed network analysis techniques. Developed approach is demonstrated to be applicable both for single agent and for multi component biochemical analysis. Novel technique based on optical resonance on microring structures, plasmon resonance and identification tools has been developed. To improve a sensitivity of microring structures microspheres fixed by adhesive had been treated previously by gold nanoparticle solution. Another technique used thin film gold layers deposited on the substrate below adhesive. Both biomolecule and nanoparticle injections caused considerable changes of optical resonance spectra. Plasmonic gold layers under optimized thickness also improve parameters of optical resonance spectra. Biochemical component identification has been also performed by developed network analysis techniques both for single and for multi component solution. So advantages of plasmon enhancing optical microcavity resonance with multiparameter identification tools is used for development of a new platform for ultra sensitive label-free biomedical sensor.

  15. Materials Development for Next Generation Optical Fiber

    PubMed Central

    Ballato, John; Dragic, Peter

    2014-01-01

    Optical fibers, the enablers of the Internet, are being used in an ever more diverse array of applications. Many of the rapidly growing deployments of fibers are in high-power and, particularly, high power-per-unit-bandwidth systems where well-known optical nonlinearities have historically not been especially consequential in limiting overall performance. Today, however, nominally weak effects, most notably stimulated Brillouin scattering (SBS) and stimulated Raman scattering (SRS) are among the principal phenomena restricting continued scaling to higher optical power levels. In order to address these limitations, the optical fiber community has focused dominantly on geometry-related solutions such as large mode area (LMA) designs. Since such scattering, and all other linear and nonlinear optical phenomena including higher order mode instability (HOMI), are fundamentally materials-based in origin, this paper unapologetically advocates material solutions to present and future performance limitations. As such, this paper represents a ‘call to arms’ for material scientists and engineers to engage in this opportunity to drive the future development of optical fibers that address many of the grand engineering challenges of our day. PMID:28788683

  16. Synthesis of Compositionally Defined Single-Crystalline Eu 3+ -Activated Molybdate–Tungstate Solid-Solution Composite Nanowires and Observation of Charge Transfer in a Novel Class of 1D CaMoO 4 –CaWO 4 :Eu 3+ –0D CdS/CdSe QD Nanoscale Heterostructures

    DOE PAGES

    Han, Jinkyu; McBean, Coray; Wang, Lei; ...

    2015-02-10

    As a first step, we have synthesized and optically characterized a systematic series of one-dimensional (1D) single-crystalline Eu³⁺-activated alkaline-earth metal tungstate/molybdate solid solution composite CaW₁₋ xMo xO₄ (0 ≤ ‘x’ ≤ 1) nanowires of controllable chemical composition using a modified template-directed methodology under ambient room-temperature conditions. Extensive characterization of the resulting nanowires has been performed using X-ray diffraction, electron microscopy, and optical spectroscopy. The crystallite size and single crystallinity of as-prepared 1D CaW₁₋ xMo xO₄: Eu³⁺ (0 ≤ ‘x’ ≤ 1) solid solution composite nanowires increase with increasing Mo component (‘x’). We note a clear dependence of luminescence output uponmore » nanowire chemical composition with our 1D CaW₁₋ xMo xO₄: Eu³⁺ (0 ≤ ‘x’ ≤ 1) evincing the highest photoluminescence (PL) output at ‘x’ = 0.8, amongst samples tested. Subsequently, coupled with either zero-dimensional (0D) CdS or CdSe quantum dots (QDs), we successfully synthesized and observed charge transfer processes in 1D CaW1-xMoxO4: Eu3+ (‘x’ = 0.8) – 0D QD composite nanoscale heterostructures. Our results show that CaW₁₋ xMo xO₄: Eu³⁺ (‘x’ = 0.8) nanowires give rise to PL quenching when CdSe QDs and CdS QDs are anchored onto the surfaces of 1D CaW₁₋ xMo xO₄: Eu³⁺ nanowires. The observed PL quenching is especially pronounced in CaW₁₋ xMo xO₄: Eu³⁺ (‘x’ = 0.8) – 0D CdSe QD heterostructures. Conversely, the PL output and lifetimes of CdSe and CdS QDs within these heterostructures are not noticeably altered as compared with unbound CdSe and CdS QDs. The difference in optical behavior between 1D Eu³⁺ activated tungstate and molybdate solid solution nanowires and the semiconducting 0D QDs within our heterostructures can be correlated with the relative positions of their conduction and valence energy band levels. We propose that the PL quenching can be attributed to a photo-induced electron transfer process from CaW₁₋ xMo xO₄: Eu³⁺ (‘x’ = 0.8) to both CdSe and CdS QDs, an assertion supported by complementary NEXAFS measurements.« less

  17. Entertaining Chemistry--Two Colorful Reactions.

    ERIC Educational Resources Information Center

    Elsworth, John F.

    2000-01-01

    Describes two related color-change reactions that are relatively easy and safe to demonstrate. In the "Sunday School Reaction", a black and a white solution are mixed to form a white solution. In the "South Africa Reaction", a series of black, brown, red, and white solutions are mixed to form a clear, colorless solution. (WRM)

  18. Can we model solute transfer in heterogeneous soils with MIM model?

    NASA Astrophysics Data System (ADS)

    Ben Slimene, Erij; Lassabatere, Laurent; Winiarski, Thierry; Gourdon, Remy

    2017-04-01

    The fate of pollutants in the vadose zone must be understood, in particular, underneath infiltration basins for an optimum management of these plants. Stormwaters carry pollutants (heavy metals, organics, emerging pollutant like nanoparticles, etc.) and thus constitute a risk for groundwater and soil quality. Most infiltration basins are settled over highly permeable soils that exhibit a strong lithological heterogeneity. The impact of such lithological heterogeneity on flow and solute transfer has already been questioned. Previous studies have already proved that lithological heterogeneity was prone to the establishment of preferential flows. In more details, the concomitance of several materials with contrasting hydraulic properties induces funneled flow at the interfaces between less permeable and more permeable lithofacies. Solutes are then carried by water fluxes quickly along preferential flow pathways and have restricted access to zones far from these pathways. It can clearly be imagined that such pattern could be modeled by a MIM model postulating water fraction into two fractions, one mobile and the other immobile, with solute transport by convection and dispersion in mobile water fraction and solute diffusion at the interface between mobile and immobile water fractions. The application of MIM approach to the case of solute transport in strongly heterogeneous soils may be quite advantageous: simplification of the problem, fewer parameters, ease of modeling, numerical computation, gain in computation time, etc. However, such consistency has never been investigated in details. In this paper, we focus on the possibility to model solute transport in a strongly heterogeneous deposit using MIM model. The deposit has been the subject of intensive campaigns of characterization of its lithology and the hydraulic and hydrodispersive properties of its lithofacies. Numerical computations were performed for a section of deposit 13.5 m wide and 2.5 m deep. Numerical results clearly showed the establishment of preferential flows with funneling mostly under unsaturated conditions. Solute elution at 2.5 m depth was characterized and discussed as a function of solute reactivity. Solutes breakthrough curves show clear evidence of MIM like pattern. In this paper, we clearly demonstrate that MIM model accurately reproduces solute elution at 2.5m depths but also at different depths. MIM approach accuracy is ensured provided that related parameters are optimized as a function of depth, hydric and hydraulic conditions and the contrast in hydraulic parameters of the lithofacies that constitute the deposit.

  19. Hyperspectrally-Resolved Surface Emissivity Derived Under Optically Thin Clouds

    NASA Technical Reports Server (NTRS)

    Zhou, Daniel K.; Larar, Allen M.; Liu, Xu; Smith, William L.; Strow, L. Larrabee; Yang, Ping

    2010-01-01

    Surface spectral emissivity derived from current and future satellites can and will reveal critical information about the Earth s ecosystem and land surface type properties, which can be utilized as a means of long-term monitoring of global environment and climate change. Hyperspectrally-resolved surface emissivities are derived with an algorithm utilizes a combined fast radiative transfer model (RTM) with a molecular RTM and a cloud RTM accounting for both atmospheric absorption and cloud absorption/scattering. Clouds are automatically detected and cloud microphysical parameters are retrieved; and emissivity is retrieved under clear and optically thin cloud conditions. This technique separates surface emissivity from skin temperature by representing the emissivity spectrum with eigenvectors derived from a laboratory measured emissivity database; in other words, using the constraint as a means for the emissivity to vary smoothly across atmospheric absorption lines. Here we present the emissivity derived under optically thin clouds in comparison with that under clear conditions.

  20. Transparent 'solution' of ultrathin magnesium hydroxide nanocrystals for flexible and transparent nanocomposite films.

    PubMed

    Wang, Jie-Xin; Sun, Qian; Chen, Bo; Wu, Xi; Zeng, Xiao-Fei; Zhang, Cong; Zou, Hai-Kui; Chen, Jian-Feng

    2015-05-15

    Transparent solutions of nanocrystals exhibit many unique properties, and are thus attractive materials for numerous applications. However, the synthesis of transparent nanocrystal solutions of magnesium hydroxide (MH) with wide applications is yet to be realized. Here, we report a facile two-step process, which includes a direct reactive precipitation in alcohol phase instead of aqueous phase combined with a successive surface modification, to prepare transparent alcohol solutions containing lamellar MH nanocrystals with an average size of 52 nm and an ultrathin thickness of 1-2 nm, which is the thinnest MH nanoplatelet reported in the literatures. Further, highly flexible and transparent nanocomposite films are fabricated with a solution mixing method by adding the transparent MH nanocrystal solutions into PVB solution. Considering the simplicity of the fabrication process, high transparency and good flexibility, this MH/polymer nanocomposite film is promising for flame-resistant applications in plastic electronics and optical devices with high transparency, such as flexible displays, optical filters, and flexible solar cells.

  1. Exact solution for four-order acousto-optic Bragg diffraction with arbitrary initial conditions.

    PubMed

    Pieper, Ron; Koslover, Deborah; Poon, Ting-Chung

    2009-03-01

    An exact solution to the four-order acousto-optic (AO) Bragg diffraction problem with arbitrary initial conditions compatible with exact Bragg angle incident light is developed. The solution, obtained by solving a 4th-order differential equation, is formalized into a transition matrix operator predicting diffracted light orders at the exit of the AO cell in terms of the same diffracted light orders at the entrance. It is shown that the transition matrix is unitary and that this unitary matrix condition is sufficient to guarantee energy conservation. A comparison of analytical solutions with numerical predictions validates the formalism. Although not directly related to the approach used to obtain the solution, it was discovered that all four generated eigenvalues from the four-order AO differential matrix operator are expressed simply in terms of Euclid's Divine Proportion.

  2. Conjugated foldamers with unusually high space-charge-limited current hole mobilities.

    PubMed

    Li, Yong; Dutta, Tanmoy; Gerasimchuk, Nikolay; Wu, Shijie; Shetye, Kuldeep; Jin, Lu; Wang, Ruixin; Zhu, Da-Ming; Peng, Zhonghua

    2015-05-13

    Charge carrier mobility and its optimization play a critical role in the development of cutting-edge organic electronic and optoelectronic devices. Even though space-charge-limited current (SCLC) hole mobilities as high as 1.4 cm(2) V(-1) s(-1) have been reported for microscopically sized highly ordered liquid-crystalline conjugated small molecules, the SCLC hole mobility of device-sized thin films of conjugated polymers is still much lower, ranging from 10(-6) to 10(-3) cm(2) V(-1) s(-1). Herein, we report the synthesis, characterizations, and thin-film SCLC mobility of three discotic conjugated polymers, INDT-TT, INDT-BT, and INDT-NDT. Optical studies indicate that polymer INDT-NDT adopts a folded conformation in solutions of good or poor solvents, whereas polymer INDT-TT stays as random monomeric chains in good solvents and interchain aggregates in poor solvents. INDT-BT polymer chains, however, stay as foldamers in dilute solutions of good solvents but interchain aggregates in concentrated solutions or poor solvents. Circular dichroism spectroscopy provides clear evidence for the helical folding of INDT-NDT in solutions. Thin films spin-coated from 1,2-dichlorobenzene solutions of the polymers show SCLC hole mobility of 2.20 × 10(-6), 8.79 × 10(-5), and 2.77 × 10(-2) cm(2) V(-1) s(-1) for INDT-TT, INDT-BT, and INDT-NDT, respectively. HRTEM and powder XRD measurements show that INDT-NDT pristine thin films contain nanocrystalline domains, whereas the INDT-TT and INDT-BT films are amorphous. Thin films of INDT-NDT:PC71BM blends show increased crystallinity and further improved SCLC hole mobility up to 1.29 × 10(-1) cm(2) V(-1) s(-1), one of the highest SCLC mobility values ever recorded on solution-processed organic semiconducting thin films. The persistent folding conformation of INDT-NDT is believed to be responsible for the high crystallinity of its thin films and its high SCLC mobilities.

  3. Towards efficient next generation light sources: combined solution processed and evaporated layers for OLEDs

    NASA Astrophysics Data System (ADS)

    Hartmann, D.; Sarfert, W.; Meier, S.; Bolink, H.; García Santamaría, S.; Wecker, J.

    2010-05-01

    Typically high efficient OLED device structures are based on a multitude of stacked thin organic layers prepared by thermal evaporation. For lighting applications these efficient device stacks have to be up-scaled to large areas which is clearly challenging in terms of high through-put processing at low-cost. One promising approach to meet cost-efficiency, high through-put and high light output is the combination of solution and evaporation processing. Moreover, the objective is to substitute as many thermally evaporated layers as possible by solution processing without sacrificing the device performance. Hence, starting from the anode side, evaporated layers of an efficient white light emitting OLED stack are stepwise replaced by solution processable polymer and small molecule layers. In doing so different solutionprocessable hole injection layers (= polymer HILs) are integrated into small molecule devices and evaluated with regard to their electro-optical performance as well as to their planarizing properties, meaning the ability to cover ITO spikes, defects and dust particles. Thereby two approaches are followed whereas in case of the "single HIL" approach only one polymer HIL is coated and in case of the "combined HIL" concept the coated polymer HIL is combined with a thin evaporated HIL. These HIL architectures are studied in unipolar as well as bipolar devices. As a result the combined HIL approach facilitates a better control over the hole current, an improved device stability as well as an improved current and power efficiency compared to a single HIL as well as pure small molecule based OLED stacks. Furthermore, emitting layers based on guest/host small molecules are fabricated from solution and integrated into a white hybrid stack (WHS). Up to three evaporated layers were successfully replaced by solution-processing showing comparable white light emission spectra like an evaporated small molecule reference stack and lifetime values of several 100 h.

  4. Intracanalicular Optic Nerve Swelling and Signal Change in Fulminant Untreated Idiopathic Intracranial Hypertension.

    PubMed

    Moodley, Anand A; Dlwati, Mahlubonke S; Durand, Miranda

    2017-04-01

    The role of the optic canal in the pathogenesis of papilloedema has been under scrutiny recently. Whether a larger canal precedes more severe papilloedema or is the result of bone remodelling from chronically raised pressure across a pressure gradient is not clear. The authors present the magnetic resonance imaging findings of a 29-year-old female with fulminant and untreated idiopathic intracranial hypertension. Imaging showed focal expansion and intrinsic signal changes of the intracanalicular optic nerve. The authors discuss the possibility of either fluid accumulation within the optic nerves from a water hammer effect across blocked optic canals resulting from the steep pressure gradient or opticomalacia (optic nerve softening) from chronic ischaemia.

  5. Application of the Kano-Hamilton multiangle inversion method in clear atmospheres

    Treesearch

    Mariana Adam; Vladimir A. Kovalev; Cyle Wold; Jenny Newton; Markus Pahlow; Wei M. Hao; Marc B. Parlange

    2007-01-01

    An improved measurement methodology and a data-processing technique for multiangle data obtained with an elastic scanning lidar in clear atmospheres are introduced. Azimuthal and slope scans are combined to reduce the atmospheric heterogeneity. Vertical profiles of optical depth and intercept (proportional to the logarithm of the backscatter coefficient) are determined...

  6. Third-order nonlinear optical properties of acid green 25 dye by Z-scan method

    NASA Astrophysics Data System (ADS)

    Jeyaram, S.; Geethakrishnan, T.

    2017-03-01

    Third-order nonlinear optical (NLO) properties of aqueous solutions of an anthraquinone dye (Acid green 25 dye, color index: 61570) have been studied by Z-scan method with a 5 mW continuous wave (CW) diode laser operating at 635 nm. The nonlinear refractive index (n2) and the absorption coefficient (β) have been evaluated respectively from the closed and open aperture Z-scan data and the values of these parameters are found to increase with increase in concentration of the dye solution. The negative sign of the observed nonlinear refractive index (n2) indicates that the aqueous solution of acid green 25 dye exhibits self-defocusing type optical nonlinearity. The mechanism of the observed nonlinear absorption (NLA) and nonlinear refraction (NLR) is attributed respectively to reverse saturable absorption (RSA) and thermal nonlinear effects. The magnitudes of n2 and β are found to be of the order of 10-7 cm2/W and 10-3 cm/W respectively. With these experimental results, the authors suggest that acid green 25 dye may have potential applications in nonlinear optics.

  7. Optical microwell assay of membrane transport kinetics.

    PubMed

    Kiskin, Nikolai I; Siebrasse, Jan P; Peters, Reiner

    2003-10-01

    In optical single transporter recording, membranes are firmly attached to flat solid substrates containing small wells or test compartments (TC). Transport of fluorescent molecules through TC-spanning membrane patches is induced by solution change and recorded by confocal microscopy. Previously, track-etched membrane filters were used to create solid substrates containing populations of randomly distributed TCs. In this study the possibilities offered by orderly TC arrays as created by laser microdrilling were explored. A theoretical framework was developed taking the convolution of membrane transport, solution change, and diffusion into account. The optical properties of orderly TC arrays were studied and the kinetics of solution change measured. Export and import through the nuclear pore complex (NPC) was analyzed in isolated envelopes of Xenopus oocyte nuclei. In accordance with previous reports nuclear transport receptor NTF2, which binds directly to NPC proteins, was found to be translocated much faster than "inert" molecules of similar size. Unexpectedly, NXT1, a homolog of NTF2 reportedly unable to bind to NPC proteins directly, was translocated as fast as NTF2. Thus, microstructured TC arrays were shown to provide optical single transporter recording with a new basis.

  8. A new method for multi-bit and qudit transfer based on commensurate waveguide arrays

    NASA Astrophysics Data System (ADS)

    Petrovic, J.; Veerman, J. J. P.

    2018-05-01

    The faithful state transfer is an important requirement in the construction of classical and quantum computers. While the high-speed transfer is realized by optical-fibre interconnects, its implementation in integrated optical circuits is affected by cross-talk. The cross-talk between densely packed optical waveguides limits the transfer fidelity and distorts the signal in each channel, thus severely impeding the parallel transfer of states such as classical registers, multiple qubits and qudits. Here, we leverage on the suitably engineered cross-talk between waveguides to achieve the parallel transfer on optical chip. Waveguide coupling coefficients are designed to yield commensurate eigenvalues of the array and hence, periodic revivals of the input state. While, in general, polynomially complex, the inverse eigenvalue problem permits analytic solutions for small number of waveguides. We present exact solutions for arrays of up to nine waveguides and use them to design realistic buses for multi-(qu)bit and qudit transfer. Advantages and limitations of the proposed solution are discussed in the context of available fabrication techniques.

  9. Study on structural and optical properties of α-(AlxCr1-x)2O3 (0 ≤ x ≤ 1) solid solutions

    NASA Astrophysics Data System (ADS)

    Jangir, Ravindra; Kumar, Dharmendra; Srihari, Velaga; Ganguli, Tapas

    2018-04-01

    We report on structural and optical properties for ternary α-(AlxCr1-x)2O3 (0 ≤ x ≤ 1) solid solutions synthesized by using solid sate reaction method. Single R-3c phase was obtained for the Aluminum composition of 0 ≤ x ≤ 1. Due to difference in the ionic radia of Al3+ and Cr3+, in plane lattice parameter showed deviation from the vegard's law. Optical absorption spectra for the solid solutions showed a blue shift of ˜ 0.5 eV in the optical gap. It has also been observed that Cr 3d level shifted towards the O 2p level in the valance band which indicates the enhancement of hybridization in the d and p levels, which is related to the delocalization of hole states, responsible for p-type conduction in wide band gap semiconductors. The results suggests that ternary α-(AlxCr1-x)2O3 (0 ≤ x ≤ 1) can be useful in the field of UV transparent electronics and UV photodetectors.

  10. Investigation of manifestation of optical properties of butterfly wings with nanoscale zinc oxide incorporation

    NASA Astrophysics Data System (ADS)

    Aideo, Swati N.; Mohanta, Dambarudhar

    2016-10-01

    In this work, microstructural and optical characteristics nanoparticles of wings of Tailed Jay (Graphium Agamemnon) butterfly were studied before and after treating it in a precursor solution of zinc acetate and ethanol. We speculate that the butterfly scales are infiltrated with ZnO nanoparticles owing to reduction of Zinc hydroxide under ambient condition. The ZnO butterfly scales so produced were characterised using optical microscopy, UV-Vis reflectance spectroscopy, and electron microscopy etc. From the reflectance spectra, we could see that after treating it in the solution, optical properties vary. We anticipate that this change may be due to the formation of ZnO nanoparticles as well as the loss in periodicity due to the chemical treatments, which could be assessed from the SEM micrographs.

  11. Effect of pH on the chemical modification of quercetin and structurally related flavonoids characterized by optical (UV-visible and Raman) spectroscopy.

    PubMed

    Jurasekova, Z; Domingo, C; Garcia-Ramos, J V; Sanchez-Cortes, S

    2014-07-07

    In this work we report the study of the chemical modifications undergone by flavonoids, especially by quercetin (QUC), under alkaline conditions by UV-visible absorption, Raman and surface-enhanced Raman scattering (SERS) spectroscopy, the study was performed in aqueous solution and also on Ag nanoparticles (AgNPs). Several processes are involved in the effect of alkaline pH both in solution and on AgNPs: autoxidation affecting mainly the C-ring of the molecule and giving rise to the molecular fragmentation leading to simpler molecular products, and/or the dimerization and further polymerization leading to species with a higher molecular weight. In addition, there exists a clear structure-instability correlation concerning mainly particular groups in the molecule: the C3-OH group in the C-ring, the catechol moiety in the B-ring and the C2=C3 bond also existing in the C-ring. QUC possesses all these groups and exhibits high instability in alkaline solution. The SERS spectra registered at different pH revealed a change in the dimerization protocol of QUC going from the A- and C-rings-like-condensation to B-ring-like-condensation. Increasing the knowledge of the chemical properties of these compounds and determining the structure-activity relationship under specific environmental factors allow us to improve their beneficial properties for health as well as the preservation of Cultural Heritage objects, for example, by preventing their degradation.

  12. Solution processable and optically switchable 1D photonic structures.

    PubMed

    Paternò, Giuseppe M; Iseppon, Chiara; D'Altri, Alessia; Fasanotti, Carlo; Merati, Giulia; Randi, Mattia; Desii, Andrea; Pogna, Eva A A; Viola, Daniele; Cerullo, Giulio; Scotognella, Francesco; Kriegel, Ilka

    2018-02-23

    We report the first demonstration of a solution processable, optically switchable 1D photonic crystal which incorporates phototunable doped metal oxide nanocrystals. The resulting device structure shows a dual optical response with the photonic bandgap covering the visible spectral range and the plasmon resonance of the doped metal oxide the near infrared. By means of a facile photodoping process, we tuned the plasmonic response and switched effectively the optical properties of the photonic crystal, translating the effect from the near infrared to the visible. The ultrafast bandgap pumping induces a signal change in the region of the photonic stopband, with recovery times of several picoseconds, providing a step toward the ultrafast optical switching. Optical modeling uncovers the importance of a complete modeling of the variations of the dielectric function of the photodoped material, including the high frequency region of the Drude response which is responsible for the strong switching in the visible after photodoping. Our device configuration offers unprecedented tunability due to flexibility in device design, covering a wavelength range from the visible to the near infrared. Our findings indicate a new protocol to modify the optical response of photonic devices by optical triggers only.

  13. Observation of the spectrally invariant properties of clouds in cloudy-to-clear transition zones during the MAGIC field campaign

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Weidong; Marshak, Alexander; McBride, Patrick J.

    2016-12-01

    We use the spectrally invariant method to study the variability of cloud optical thickness τ and droplet effective radius reff in transition zones (between the cloudy and clear sky columns) observed from Solar Spectral Flux Radiometer (SSFR) and Shortwave Array Spectroradiometer-Zenith (SASZe) during the Marine ARM GPCI Investigation of Clouds (MAGIC) field campaign. The measurements from the SSFR and the SASZe are different, however inter-instrument differences of self-normalized measurements (divided by their own spectra at a fixed time) are small. The spectrally invariant method approximates the spectra in the cloud transition zone as a linear combination of definitely clear andmore » cloudy spectra, where the coefficients, slope and intercept, character-ize the spectrally invariant properties of the transition zone. Simulation results from the SBDART (Santa Barbara DISORT Atmospheric Radiative Transfer) model demonstrate that (1) the slope of the visible band is positively correlated with the cloud optical thickness τ while the intercept of the near-infrared band has high negative cor-relation with the cloud drop effective radius reff even without the exact knowledge of τ; (2) the above relations hold for all Solar Zenith Angle (SZA) and for cloud-contaminated skies. In observations using redundant measure-ments from SSFR and SASZe, we find that during cloudy-to-clear transitions, (a) the slopes of the visible band de-crease, and (b) the intercepts of the near-infrared band remain almost constant near cloud edges. The findings in simulations and observations suggest that, while the optical thickness decreases during the cloudy-to-clear transition, the cloud drop effective radius does not change when cloud edges are approached. These results sup-port the hypothesis that inhomogeneous mixing dominates near cloud edges in the studied cases.« less

  14. Developing 3D microscopy with CLARITY on human brain tissue: Towards a tool for informing and validating MRI-based histology.

    PubMed

    Morawski, Markus; Kirilina, Evgeniya; Scherf, Nico; Jäger, Carsten; Reimann, Katja; Trampel, Robert; Gavriilidis, Filippos; Geyer, Stefan; Biedermann, Bernd; Arendt, Thomas; Weiskopf, Nikolaus

    2017-11-28

    Recent breakthroughs in magnetic resonance imaging (MRI) enabled quantitative relaxometry and diffusion-weighted imaging with sub-millimeter resolution. Combined with biophysical models of MR contrast the emerging methods promise in vivo mapping of cyto- and myelo-architectonics, i.e., in vivo histology using MRI (hMRI) in humans. The hMRI methods require histological reference data for model building and validation. This is currently provided by MRI on post mortem human brain tissue in combination with classical histology on sections. However, this well established approach is limited to qualitative 2D information, while a systematic validation of hMRI requires quantitative 3D information on macroscopic voxels. We present a promising histological method based on optical 3D imaging combined with a tissue clearing method, Clear Lipid-exchanged Acrylamide-hybridized Rigid Imaging compatible Tissue hYdrogel (CLARITY), adapted for hMRI validation. Adapting CLARITY to the needs of hMRI is challenging due to poor antibody penetration into large sample volumes and high opacity of aged post mortem human brain tissue. In a pilot experiment we achieved transparency of up to 8 mm-thick and immunohistochemical staining of up to 5 mm-thick post mortem brain tissue by a combination of active and passive clearing, prolonged clearing and staining times. We combined 3D optical imaging of the cleared samples with tailored image processing methods. We demonstrated the feasibility for quantification of neuron density, fiber orientation distribution and cell type classification within a volume with size similar to a typical MRI voxel. The presented combination of MRI, 3D optical microscopy and image processing is a promising tool for validation of MRI-based microstructure estimates. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  15. Observation of the Spectrally Invariant Properties of Clouds in Cloudy-to-Clear Transition Zones During the MAGIC Field Campaign

    NASA Technical Reports Server (NTRS)

    Yang, Weidong; Marshak, Alexander; McBride, Patrick; Chiu, J. Christine; Knyazikhin, Yuri; Schmidt, K. Sebastian; Flynn, Connor; Lewis, Ernie R.; Eloranta, Edwin W.

    2016-01-01

    We use the spectrally invariant method to study the variability of cloud optical thickness tau and droplet effective radius r(sub eff) in transition zones (between the cloudy and clear sky columns) observed from Solar Spectral Flux Radiometer (SSFR) and Shortwave Array Spectroradiometer-Zenith (SASZe) during the Marine ARM GPCI Investigation of Clouds (MAGIC) field campaign. The measurements from the SSFR and the SASZe are different, however inter-instrument differences of self-normalized measurements (divided by their own spectra at a fixed time) are small. The spectrally invariant method approximates the spectra in the cloud transition zone as a linear combination of definitely clear and cloudy spectra, where the coefficients, slope and intercept, characterize the spectrally invariant properties of the transition zone. Simulation results from the SBDART (Santa Barbara DISORT Atmospheric Radiative Transfer) model demonstrate that (1) the slope of the visible band is positively correlated with the cloud optical thickness t while the intercept of the near-infrared band has high negative correlation with the cloud drop effective radius r(sub eff)even without the exact knowledge of tau; (2) the above relations hold for all Solar Zenith Angle (SZA) and for cloud-contaminated skies. In observations using redundant measurements from SSFR and SASZe, we find that during cloudy-to-clear transitions, (a) the slopes of the visible band decrease, and (b) the intercepts of the near-infrared band remain almost constant near cloud edges. The findings in simulations and observations suggest that, while the optical thickness decreases during the cloudy-to-clear transition, the cloud drop effective radius does not change when cloud edges are approached. These results support the hypothesis that inhomogeneous mixing dominates near cloud edges in the studied cases.

  16. Optical Characterization of Wide Field-of-View Night Vision Devices

    DTIC Science & Technology

    1999-01-01

    This paper has been cleared by ASC 99-2354 Optical Characterization of Wide Field-Of-View Night Vision Devices Peter L. Marasco and H. Lee Task Air...the SAFE SocietyÕs 36th Annual Symposium. Task, H.L., Hartman, R., Marasco , P.L., Zobel, A, (1993) Methods for measuring characteristics of night

  17. Arsenic complexes optical signatures in As-doped HgCdTe

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gemain, F.; Robin, I. C.; Brochen, S.

    2013-04-08

    In this paper, the optical signatures of arsenic complexes in As-doped HgCdTe samples grown by molecular beam epitaxy are clearly identified using comparison between photoluminescence spectra, Extended X-Ray Absorption Fine Structure, and Hall measurements. The ionization energies of the different complexes are measured both by photoluminescence and Hall measurements.

  18. Highly sensitive evanescent wave combination tapered fiber optic fluorosensor for protein detection

    NASA Astrophysics Data System (ADS)

    Nardone, Vincent; Kapoor, Rakesh

    2008-02-01

    In this paper we are reporting the development of a highly sensitive evanescent wave combination tapered fiber optic fluorosensor. We have demonstrated detection of 5 pM Bovine Serum Albumin (BSA) protein using these fiber optic sensors. The sensor can be easily adopted for detection of other proteins. Six identical probes were prepared and affinity pure Goat anti-BSA antibodies were immobilized on the probe surface. We could detect signal from all the probes kept in 5 pM to 1 nM BSA solution while no signal was detected from the probes kept in 20 nM labeled ESA solution.

  19. Freezing optical rogue waves by Zeno dynamics

    NASA Astrophysics Data System (ADS)

    Bayındır, Cihan; Ozaydin, Fatih

    2018-04-01

    We investigate the Zeno dynamics of the optical rogue waves. Considering their usage in modeling rogue wave dynamics, we analyze the Zeno dynamics of the Akhmediev breathers, Peregrine and Akhmediev-Peregrine soliton solutions of the nonlinear Schrödinger equation. We show that frequent measurements of the wave inhibits its movement in the observation domain for each of these solutions. We analyze the spectra of the rogue waves under Zeno dynamics. We also analyze the effect of observation frequency on the rogue wave profile and on the probability of lingering of the wave in the observation domain. Our results can find potential applications in optics including nonlinear phenomena.

  20. Enhanced optical rotation and diminished depolarization in diffusive scattering from a chiral liquid

    NASA Astrophysics Data System (ADS)

    Silverman, M. P.; Strange, Wayne; Badoz, J.; Vitkin, I. A.

    1996-02-01

    Optical rotation and degree of polarization of linearly polarized light were observed by forward, lateral, and back scattering from solutions of D-glucose containing a dispersion of micron-size polystyrene spheres. Rotations increased linearly with glucose concentration at a rate determined by the microsphere concentration and were large even at optical thicknesses sufficiently great to extinguish transmission of the incident beam. Depolarization of light with increasing microsphere concentration occurred at a much slower rate in chiral glucose solution than in pure water. These experiments suggest new possibilities for studying turbid chiral media for which light transmission and specular reflection techniques are inappropriate.

  1. Effect of Phosphine-Free Selenium Precursor Reactivity on The Optical and Vibrational properties of Colloidal CdSe Nanocrystals

    NASA Astrophysics Data System (ADS)

    Thi, L. A.; Lieu, N. T. T.; Hoa, N. M.; Tran, N.; Binh, N. T.; Quang, V. X.; Nghia, N. X.

    2018-03-01

    Phosphine-free selenium precursor solutions have been prepared by heating at temperatures ranging from 160 °C to 240 °C and studied by means of infrared absorption spectroscopy. The colloidal CdSe nanocrystals (NCs) synthesized from all those solutions by the wet chemical method. The influence of heating temperature on the chemical reactivity of selenium precursor and its role on the optical and vibrational properties of CdSe NCs are discussed in details. Their morphology, particle size, structural, optical and vibrational properties were investigated using transmission electron microscopy, X-ray diffraction, UV-Vis, fluorescence and Raman spectroscopy, respectively.

  2. Elucidation of the mechanisms of optical clearing in collagen tissue with multiphoton imaging

    NASA Astrophysics Data System (ADS)

    Hovhannisyan, Vladimir; Hu, Po-Sheng; Chen, Shean-Jen; Kim, Chang-Seok; Dong, Chen-Yuan

    2013-04-01

    Optical clearing (OC) is a promising method to overcome limitations in biomedical depth-resolved optical studies. Mechanisms of OC in purified bovine Achilles tendon, chicken skin, and chicken tendon were studied using time-lapsed, three-dimensional second harmonic generation (SHG) and two-photon fluorescence microscopic imaging. Quantified nonlinear optical measurements allowed temporal separation of two processes in collagen OC with glycerol. The first one is a fast process of tissue dehydration accompanied with collagen shrinkage and the second relatively slow process is glycerol penetration into the interfibrillar space of collagen alongside with CF swelling. The use of 50% glycerol induced less-expressed OC via partial substitution of water molecules with glycerol molecules. We also found that phosphate-buffered saline- and glycerol-treatments were reversible, and fiber morphology and SHG signal intensity were recovered after the removal of immersion agents. It was shown that tissue OC was a dynamic process and elucidation of its physical mechanisms may help choose optimal diagnostic, treatment, and modification regimes for collagen-based as well as other types of biomaterials.

  3. Comparison of optics and performance of a distal sensor high definition cystoscope, a distal sensor standard definition cystoscope, and a fiberoptic cystoscope.

    PubMed

    Lusch, Achim; Liss, Michael A; Greene, Peter; Abdelshehid, Corollos; Menhadji, Ashleigh; Bucur, Philip; Alipanah, Reza; McDougall, Elspeth; Landman, Jaime

    2013-12-01

    To evaluate performance characteristics and optics of a new generation high-definition distal sensor (HD-DS) flexible cystoscope, a standard-definition distal sensor (SD-DS) cystoscope, and a standard fiberoptic (FO) cystoscope. Three new cystoscopes (HD-DS, SD-DS, and FO) were compared for active deflection, irrigation flow, and optical characteristics. Each cystoscope was evaluated with an empty working channel and with various accessories. Optical characteristics (resolution, grayscale imaging, color representation, depth of field, and image brightness) were measured using United States Air Force (USAF)/Edmund Optics test targets and illumination meter. We digitally recorded a porcine cystoscopy in both clear and blood fields, with subsequent video analysis by 8 surgeons via questionnaire. The HD-DS had a higher resolution than the SD-DS and the FO at both 20 mm (6.35 vs 4.00 vs 2.24 line pairs/mm) and 10 mm (14.3 vs 7.13 vs 4.00 line pairs/mm) evaluations, respectively (P <.001 and P <.001). Color representation and depth of field (P = .001 and P <.001) were better in the HD-DS. When compared to the FO, the HD-DS and SD-DS demonstrated superior deflection up and irrigant flow with and without accessory present in the working channel, whereas image brightness was superior in the FO (P <.001, P = .001, and P <.001, respectively). Observers deemed the HD-DS cystoscope superior in visualization in clear and bloody fields, as well as for illumination. The new HD-DS provided significantly improved visualization in a clear and a bloody field, resolution, color representation, and depth of field compared to SD-DS and FO. Clinical correlation of these findings is pending. Copyright © 2013 Elsevier Inc. All rights reserved.

  4. Optical Sensors and Methods for Underwater 3D Reconstruction

    PubMed Central

    Massot-Campos, Miquel; Oliver-Codina, Gabriel

    2015-01-01

    This paper presents a survey on optical sensors and methods for 3D reconstruction in underwater environments. The techniques to obtain range data have been listed and explained, together with the different sensor hardware that makes them possible. The literature has been reviewed, and a classification has been proposed for the existing solutions. New developments, commercial solutions and previous reviews in this topic have also been gathered and considered. PMID:26694389

  5. Experimental demonstration of bandwidth on demand (BoD) provisioning based on time scheduling in software-defined multi-domain optical networks

    NASA Astrophysics Data System (ADS)

    Zhao, Yongli; Li, Yajie; Wang, Xinbo; Chen, Bowen; Zhang, Jie

    2016-09-01

    A hierarchical software-defined networking (SDN) control architecture is designed for multi-domain optical networks with the Open Daylight (ODL) controller. The OpenFlow-based Control Virtual Network Interface (CVNI) protocol is deployed between the network orchestrator and the domain controllers. Then, a dynamic bandwidth on demand (BoD) provisioning solution is proposed based on time scheduling in software-defined multi-domain optical networks (SD-MDON). Shared Risk Link Groups (SRLG)-disjoint routing schemes are adopted to separate each tenant for reliability. The SD-MDON testbed is built based on the proposed hierarchical control architecture. Then the proposed time scheduling-based BoD (Ts-BoD) solution is experimentally demonstrated on the testbed. The performance of the Ts-BoD solution is evaluated with respect to blocking probability, resource utilization, and lightpath setup latency.

  6. Optical analogue of relativistic Dirac solitons in binary waveguide arrays

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tran, Truong X., E-mail: truong.tran@mpl.mpg.de; Max Planck Institute for the Science of Light, Günther-Scharowsky str. 1, 91058 Erlangen; Longhi, Stefano

    2014-01-15

    We study analytically and numerically an optical analogue of Dirac solitons in binary waveguide arrays in the presence of Kerr nonlinearity. Pseudo-relativistic soliton solutions of the coupled-mode equations describing dynamics in the array are analytically derived. We demonstrate that with the found soliton solutions, the coupled mode equations can be converted into the nonlinear relativistic 1D Dirac equation. This paves the way for using binary waveguide arrays as a classical simulator of quantum nonlinear effects arising from the Dirac equation, something that is thought to be impossible to achieve in conventional (i.e. linear) quantum field theory. -- Highlights: •An opticalmore » analogue of Dirac solitons in nonlinear binary waveguide arrays is suggested. •Analytical solutions to pseudo-relativistic solitons are presented. •A correspondence of optical coupled-mode equations with the nonlinear relativistic Dirac equation is established.« less

  7. Optoacoustic response from graphene-based solutions embedded in optical phantoms by using 905-nm high-power diode-laser assemblies

    NASA Astrophysics Data System (ADS)

    Leggio, Luca; Gallego, Daniel C.; Gawali, Sandeep Babu; Dadrasnia, Ehsan; Sánchez, Miguel; Rodríguez, Sergio; González, Marta; Carpintero, Guillermo; Osiński, Marek; Lamela, Horacio

    2016-03-01

    During the last two decades, optoacoustic imaging has been developed as a novel biomedical imaging technique based on the generation of ultrasound waves by means of laser light. In this work, we investigate the optoacoustic response from graphene-based solutions by using a compact and cost-effective system based on an assembly of several 905-nm pulsed high-power diode lasers coupled to a bundle of 200-μm diameter- core optical fibers. The coupled light is conveyed into a lens system and focused on an absorber consisting of graphene-based nanomaterials (graphene oxide, reduced graphene oxide, and reduced graphene-oxide/gold-nanoparticle hybrid, respectively) diluted in ethanol and hosted in slightly scattering optical phantoms. The high absorption of these graphene-based solutions suggests their potential future use in optoacoustic applications as contrast agents.

  8. Mobile free-space optical communications: a feasibility study of various battlefield scenarios

    NASA Astrophysics Data System (ADS)

    Harris, Alan; Al-Akkoumi, Mouhammad K.; Sluss, James J., Jr.

    2012-06-01

    Free Space Optics (FSO) technology was originally envisioned to be a viable solution for the provision of high bandwidth optical connectivity in the last mile of today's telecommunications infrastructure. Due to atmospheric limitations inherent to FSO technology, FSO is now widely envisioned as a solution for the provision of high bandwidth, temporary mobile communications links. The need for FSO communications links will increase as mobility is introduced to this technology. In this paper, a theoretical solution for adding mobility to FSO communication links is introduced. Three-dimensional power estimation studies are presented to represent mobile FSO transmission under various weather conditions. Three wavelengths, 0.85, 1.55 and 10 um, are tested and compared to illustrate the pros and cons of each source wavelength used for transmission, depending on prevalent weather conditions and atmospheric turbulence conditions. A simulation analysis of the transmission properties of the source wavelengths used in the study is shown.

  9. Acoustooptic linear algebra processors - Architectures, algorithms, and applications

    NASA Technical Reports Server (NTRS)

    Casasent, D.

    1984-01-01

    Architectures, algorithms, and applications for systolic processors are described with attention to the realization of parallel algorithms on various optical systolic array processors. Systolic processors for matrices with special structure and matrices of general structure, and the realization of matrix-vector, matrix-matrix, and triple-matrix products and such architectures are described. Parallel algorithms for direct and indirect solutions to systems of linear algebraic equations and their implementation on optical systolic processors are detailed with attention to the pipelining and flow of data and operations. Parallel algorithms and their optical realization for LU and QR matrix decomposition are specifically detailed. These represent the fundamental operations necessary in the implementation of least squares, eigenvalue, and SVD solutions. Specific applications (e.g., the solution of partial differential equations, adaptive noise cancellation, and optimal control) are described to typify the use of matrix processors in modern advanced signal processing.

  10. Method and system for suppression of stimulated Raman scattering in laser materials

    DOEpatents

    Caird, John A; Bayramian, Andrew J; Ebbers, Christopher A

    2013-11-19

    A composition of matter is provided having the general chemical formula K(H,D).sub.2P(.sup.16O.sub.x,.sup.18O.sub.y).sub.4, where x<0.998 or y>0.002, and x+y.apprxeq.1. Additionally, a method of fabricating an optical material by growth from solution is provided. The method includes providing a solution including a predetermined percentage of (H,D).sub.2.sup.16O and a predetermined percentage of (H,D).sub.2.sup.18O, providing a seed crystal, and supporting the seed crystal on a platform. The method also includes immersing the seed crystal in the solution and forming the optical material. The optical material has the general chemical formula K(H,D).sub.2P(.sup.16O.sub.x,.sup.18O.sub.y).sub.4, where x<0.998 or y>0.002, and x+y.apprxeq.1.

  11. Method and system for suppression of stimulated Raman scattering in laser materials

    DOEpatents

    Caird, John A.; Bayramian, Andrew J.; Ebbers, Christopher A.

    2015-07-14

    A composition of matter is provided having the general chemical formula K(H,D).sub.2P(.sup.16O.sub.x,.sup.18O.sub.y).sub.4, where x<0.998 or y>0.002, and x+y.apprxeq.1. Additionally, a method of fabricating an optical material by growth from solution is provided. The method includes providing a solution including a predetermined percentage of (H,D).sub.2.sup.16O and a predetermined percentage of (H,D).sub.2.sup.18O, providing a seed crystal, and supporting the seed crystal on a platform. The method also includes immersing the seed crystal in the solution and forming the optical material. The optical material has the general chemical formula K(H,D).sub.2P(.sup.16O.sub.x,.sup.18O.sub.y).sub.4, where x<0.998 or y>0.002, and x+y.apprxeq.1.

  12. Innovative hybrid optics: combining the thermal stability of glass with low manufacturing cost of polymers

    NASA Astrophysics Data System (ADS)

    Doushkina, Valentina

    2010-08-01

    Innovative hybrid glass-polymer optical solutions on a component, module, or system level offer thermal stability of glass with low manufacturing cost of polymers reducing component weight, enhancing the safety and appeal of the products. Narrow choice of polymer materials is compensated by utilizing sophisticated optical surfaces such as refractive, reflective, and diffractive substrates with spherical, aspherical, cylindrical, and freeform prescriptions. Current advancements in polymer technology and injection molding capabilities placed polymer optics in the heart of many high tech devices and applications including Automotive Industry, Defense & Aerospace; Medical/Bio Science; Projection Displays, Sensors, Information Technology, Commercial and Industrial. This paper is about integration of polymer and glass optics for enhanced optical performance with reduced number of components, thermal stability, and low manufacturing cost. The listed advantages are not achievable when polymers or glass optics are used as stand-alone. The author demonstrates that integration of polymer and glass on component or optical system level on one hand offers high resolution and diffraction limited image quality, similar to the glass optics with stable refractive index and stable thermal performance when design is athermalized within the temperature range. On the other hand, the integrated hybrid solution significantly reduces cost, weight, and complexity, just like the polymer optics. The author will describe the design and analyzes process of combining glass and polymer optics for variety of challenging applications such as fast optics with low F/#, wide field of view lenses or systems, free form optics, etc.

  13. High-Temperature Optical Window Design

    NASA Technical Reports Server (NTRS)

    Roeloffs, Norman; Taranto, Nick

    1995-01-01

    A high-temperature optical window is essential to the optical diagnostics of high-temperature combustion rigs. Laser Doppler velocimetry, schlieren photography, light sheet visualization, and laser-induced fluorescence spectroscopy are a few of the tests that require optically clear access to the combustor flow stream. A design was developed for a high-temperature window that could withstand the severe environment of the NASA Lewis 3200 F Lean Premixed Prevaporized (LPP) Flame Tube Test Rig. The development of this design was both time consuming and costly. This report documents the design process and the lessons learned, in an effort to reduce the cost of developing future designs for high-temperature optical windows.

  14. The role of cerebral spinal fluid in light propagation through the mouse head: improving fluorescence tomography with Monte Carlo modeling

    NASA Astrophysics Data System (ADS)

    Ancora, Daniele; Zacharopoulos, Athanasios; Ripoll, Jorge; Zacharakis, Giannis

    2016-03-01

    Optical Neuroimaging is a highly dynamical field of research owing to the combination of many advanced imaging techniques and computational tools that uncovered unexplored paths through the functioning of the brain. Light propagation modelling through such complicated structures has always played a crucial role as the basis for a high resolution and quantitative imaging where even the slightest improvement could lead to significant results. Fluorescence Diffuse Optical Tomography (fDOT), a widely used technique for three dimensional imaging of small animals and tissues, has been proved to be inaccurate for neuroimaging the mouse head without the knowledge of a-priori anatomical information of the subject. Commonly a normalized Born approximation model is used in fDOT reconstruction based on forward photon propagation using Diffusive Equation (DE) which has strong limitations in the optically clear regime. The presence of the Cerebral Spinal Fluid (CSF) instead, a thin optically clear layer surrounding the brain, can be more accurately taken into account using Monte Carlo approaches which nowadays is becoming more usable thanks to parallelized GPU algorithms. In this work we discuss the results of a synthetic experimental comparison, resulting to the increase of the accuracy for the Born approximation by introducing the CSF layer in a realistic mouse head structure with respect to the current model. We point out the importance of such clear layer for complex geometrical models, while for simple slab phantoms neglecting it does not introduce a significant error.

  15. Modules and methods for all photonic computing

    DOEpatents

    Schultz, David R.; Ma, Chao Hung

    2001-01-01

    A method for all photonic computing, comprising the steps of: encoding a first optical/electro-optical element with a two dimensional mathematical function representing input data; illuminating the first optical/electro-optical element with a collimated beam of light; illuminating a second optical/electro-optical element with light from the first optical/electro-optical element, the second optical/electro-optical element having a characteristic response corresponding to an iterative algorithm useful for solving a partial differential equation; iteratively recirculating the signal through the second optical/electro-optical element with light from the second optical/electro-optical element for a predetermined number of iterations; and, after the predetermined number of iterations, optically and/or electro-optically collecting output data representing an iterative optical solution from the second optical/electro-optical element.

  16. New analytical methodology for analysing S(IV) species at low pH solutions by one stage titration method (bichromatometry) with a clear colour change. Could potentially replace the state-of-art-method iodometry at low pH analysis due higher accuracy

    PubMed Central

    Galfi, Istvan; Virtanen, Jorma; Gasik, Michael M.

    2017-01-01

    A new, faster and more reliable analytical methodology for S(IV) species analysis at low pH solutions by bichromatometry is proposed. For decades the state of the art methodology has been iodometry that is still well justified method for neutral solutions, thus at low pH media possess various side reactions increasing inaccuracy. In contrast, the new methodology has no side reactions at low pH media, requires only one titration step and provides a clear color change if S(IV) species are present in the solution. The method is validated using model solutions with known concentrations and applied to analyses of gaseous SO2 from purged solution in low pH media samples. The results indicate that bichromatometry can accurately analyze SO2 from liquid samples having pH even below 0 relevant to metallurgical industrial processes. PMID:29145479

  17. Synthesis, structural and optical properties of ZnO spindle/reduced graphene oxide composites with enhanced photocatalytic activity under visible light irradiation

    NASA Astrophysics Data System (ADS)

    Prabhu, S.; Pudukudy, M.; Sohila, S.; Harish, S.; Navaneethan, M.; Navaneethan, D.; Ramesh, R.; Hayakawa, Y.

    2018-05-01

    In the present work, spindle-shaped ZnO and reduced graphene oxide sheets were successfully synthesized by a hydrothermal method and then ZnO/r-GO composite was prepared by a direct solution mixing method. Various characterization results confirmed the interior and surface decoration of spindle-shaped ZnO on the reduced graphene oxide sheets. The phase formation, crystalline structure, morphology, surface states and optical properties were characterized using Powder X-ray diffraction (XRD), Field emission scanning electron microscopy (FESEM), Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Fourier Transform Infrared Spectroscopy (FTIR) and UV-Vis spectroscopy. The X-ray diffraction analysis showed the formation of the hexagonal wurtzite crystalline structure of ZnO with high crystalline quality. The band gap of the ZnO/r-GO composite was found to be low (3.03eV) compared to the band gap of spindle shaped ZnO (3.13 eV), as calculated from optical studies. The spindle-like morphology of the single crystalline ZnO was clearly shown in the electron microscopic images. The chemical bonding and surface states of the samples were studied using XPS measurement. Moreover, a possible growth mechanism for the ZnO spindle was proposed. The catalytic activity of the as-synthesized samples was evaluated for the photodegradation of methylene blue under visible light irradiation. Among the synthesized samples, the ZnO/r-GO composite showed higher degradation efficiency of 93% and successfully reused for four consecutive run without any activity loss.

  18. Advanced integrated WDM system for POF communication

    NASA Astrophysics Data System (ADS)

    Haupt, M.; Fischer, U. H. P.

    2009-01-01

    Polymer Optical Fibres (POFs) show clear advantages compared to copper and glass fibres. In essence, POFs are inexpensive, space-saving and not susceptible to electromagnetic interference. Thus, the usage of POFs have become a reasonable alternative in short distance data communication. Today, POFs are applied in a wide number of applications due to these specific advantages. These applications include automotive communication systems and in-house-networks. State-of-the-art is to transmit data with only one channel over POF, this limits the bandwidth. To solve this problem, an integrated MUX/DEMUX-element for WDM over POF is designed and developed to use multiple channels. This integration leads to low costs, therefore this component is suitable for mass market applications. The fundamental idea is to separate the chromatic parts of the light in its monochromatic components by means of a grating based on an aspheric mirror. Due to the high NA of the POF the setup has to be designed in a 3D-approach. Therefore this setup cannot be compared with the planar solutions available on market, they would result high losses in the 3rd dimension. To achieve a fast and optimized design an optical simulation program is used. Particular attention has to be paid to the design of the POF as a light source in the simulation program and the optimisation of the grating. The following realization of the demultiplexer is planed to be done with injection molding. This technology offers easy and very economical processing. These advantages make this technology first choice for optical components in the low-cost array.

  19. Cloud and aerosol optical depths

    NASA Technical Reports Server (NTRS)

    Pueschel, R. F.; Russell, P. B.; Ackerman, Thomas P.; Colburn, D. C.; Wrigley, R. C.; Spanner, M. A.; Livingston, J. M.

    1988-01-01

    An airborne Sun photometer was used to measure optical depths in clear atmospheres between the appearances of broken stratus clouds, and the optical depths in the vicinity of smokes. Results show that (human) activities can alter the chemical and optical properties of background atmospheres to affect their spectral optical depths. Effects of water vapor adsorption on aerosol optical depths are apparent, based on data of the water vapor absorption band centered around 940 nm. Smoke optical depths show increases above the background atmosphere by up to two orders of magnitude. When the total optical depths measured through clouds were corrected for molecular scattering and gaseous absorption by subtracting the total optical depths measured through the background atmosphere, the resultant values are lower than those of the background aerosol at short wavelengths. The spectral dependence of these cloud optical depths is neutral, however, in contrast to that of the background aerosol or the molecular atmosphere.

  20. Evaluation of insertion characteristics of less invasive Si optoneural probe with embedded optical fiber

    NASA Astrophysics Data System (ADS)

    Morikawa, Takumi; Harashima, Takuya; Kino, Hisashi; Fukushima, Takafumi; Tanaka, Tetsu

    2017-04-01

    A less invasive Si optoneural probe with an embedded optical fiber was proposed and successfully fabricated. The diameter of the optical fiber was completely controlled by hydrogen fluoride etching, and the thinned optical fiber can propagate light without any leakage. This optical fiber was embedded in a trench formed inside a probe shank, which causes less damage to tissues. In addition, it was confirmed that the optical fiber embedded in the probe shank successfully irradiated light to optically stimulate gene transfected neurons. The electrochemical impedance of the probe did not change despite the light irradiation. Furthermore, probe insertion characteristics were evaluated in detail and less invasive insertion was clearly indicated for the Si optoneural probe with the embedded optical fiber compared with conventional optical neural probes. This neural probe with the embedded optical fiber can be used as a simple and easy tool for optogenetics and brain science.

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