Sonification of optical coherence tomography data and images

PubMed Central

Ahmad, Adeel; Adie, Steven G.; Wang, Morgan; Boppart, Stephen A.

2010-01-01

Sonification is the process of representing data as non-speech audio signals. In this manuscript, we describe the auditory presentation of OCT data and images. OCT acquisition rates frequently exceed our ability to visually analyze image-based data, and multi-sensory input may therefore facilitate rapid interpretation. This conversion will be especially valuable in time-sensitive surgical or diagnostic procedures. In these scenarios, auditory feedback can complement visual data without requiring the surgeon to constantly monitor the screen, or provide additional feedback in non-imaging procedures such as guided needle biopsies which use only axial-scan data. In this paper we present techniques to translate OCT data and images into sound based on the spatial and spatial frequency properties of the OCT data. Results obtained from parameter-mapped sonification of human adipose and tumor tissues are presented, indicating that audio feedback of OCT data may be useful for the interpretation of OCT images. PMID:20588846

Integrated packaging of 2D MOEMS mirrors with optical position feedback

NASA Astrophysics Data System (ADS)

Baumgart, M.; Lenzhofer, M.; Kremer, M. P.; Tortschanoff, A.

2015-02-01

Many applications of MOEMS microscanners rely on accurate position feedback. For MOEMS devices which do not have intrinsic on-chip feedback, position information can be provided with optical methods, most simply by using a reflection from the backside of a MOEMS scanner. By measuring the intensity distribution of the reflected beam across a quadrant diode, one can precisely detect the mirror's deflection angles. Previously, we have presented a position sensing device, applicable to arbitrary trajectories, which is based on the measurement of the position of the reflected laser beam with a quadrant diode. In this work, we present a novel setup, which comprises the optical position feedback functionality integrated into the device package itself. The new device's System-in-Package (SiP) design is based on a flip-folded 2.5D PCB layout and fully assembled as small as 9.2×7×4 mm³ in total. The device consists of four layers, which supply the MOEMS mirror, a spacer to provide the required optical path length, the quadrant photo-diode and a laser diode to serve as the light source. In addition to describing the mechanical setup of the novel device, we will present first experimental results and optical simulation studies. Accurate position feedback is the basis for closed-loop control of the MOEMS devices, which is crucial for some applications as image projection for example. Position feedback and the possibility of closed-loop control will significantly improve the performance of these devices.

A learning tool for optical and microwave satellite image processing and analysis

NASA Astrophysics Data System (ADS)

Dashondhi, Gaurav K.; Mohanty, Jyotirmoy; Eeti, Laxmi N.; Bhattacharya, Avik; De, Shaunak; Buddhiraju, Krishna M.

2016-04-01

This paper presents a self-learning tool, which contains a number of virtual experiments for processing and analysis of Optical/Infrared and Synthetic Aperture Radar (SAR) images. The tool is named Virtual Satellite Image Processing and Analysis Lab (v-SIPLAB) Experiments that are included in Learning Tool are related to: Optical/Infrared - Image and Edge enhancement, smoothing, PCT, vegetation indices, Mathematical Morphology, Accuracy Assessment, Supervised/Unsupervised classification etc.; Basic SAR - Parameter extraction and range spectrum estimation, Range compression, Doppler centroid estimation, Azimuth reference function generation and compression, Multilooking, image enhancement, texture analysis, edge and detection. etc.; SAR Interferometry - BaseLine Calculation, Extraction of single look SAR images, Registration, Resampling, and Interferogram generation; SAR Polarimetry - Conversion of AirSAR or Radarsat data to S2/C3/T3 matrix, Speckle Filtering, Power/Intensity image generation, Decomposition of S2/C3/T3, Classification of S2/C3/T3 using Wishart Classifier [3]. A professional quality polarimetric SAR software can be found at [8], a part of whose functionality can be found in our system. The learning tool also contains other modules, besides executable software experiments, such as aim, theory, procedure, interpretation, quizzes, link to additional reading material and user feedback. Students can have understanding of Optical and SAR remotely sensed images through discussion of basic principles and supported by structured procedure for running and interpreting the experiments. Quizzes for self-assessment and a provision for online feedback are also being provided to make this Learning tool self-contained. One can download results after performing experiments.

Digital adaptive optics line-scanning confocal imaging system.

PubMed

Liu, Changgeng; Kim, Myung K

2015-01-01

A digital adaptive optics line-scanning confocal imaging (DAOLCI) system is proposed by applying digital holographic adaptive optics to a digital form of line-scanning confocal imaging system. In DAOLCI, each line scan is recorded by a digital hologram, which allows access to the complex optical field from one slice of the sample through digital holography. This complex optical field contains both the information of one slice of the sample and the optical aberration of the system, thus allowing us to compensate for the effect of the optical aberration, which can be sensed by a complex guide star hologram. After numerical aberration compensation, the corrected optical fields of a sequence of line scans are stitched into the final corrected confocal image. In DAOLCI, a numerical slit is applied to realize the confocality at the sensor end. The width of this slit can be adjusted to control the image contrast and speckle noise for scattering samples. DAOLCI dispenses with the hardware pieces, such as Shack–Hartmann wavefront sensor and deformable mirror, and the closed-loop feedbacks adopted in the conventional adaptive optics confocal imaging system, thus reducing the optomechanical complexity and cost. Numerical simulations and proof-of-principle experiments are presented that demonstrate the feasibility of this idea.

Comparison of two reconfigurable N×N interconnects for a recurrent neural network

NASA Astrophysics Data System (ADS)

Berger, Christoph; Collings, Neil; Pourzand, Ali R.; Volkel, Reinnard

1996-11-01

Two different methods of pattern replication (conventional and interlaced fan-out) have been investigated and experimentally tested in a reconfigurable 5X5 optical interconnect. Similar alignment problems due to imaging errors (field curvature) were observed in both systems. We conclude that of the two methods the interlaced fan-out is better suited to avoid these imaging errors, to reduce system size and to implement an optical feedback loop.

NGC 3393: multi-component AGN feedback as seen by CHEERS

NASA Astrophysics Data System (ADS)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Raymond, John C.; Storchi-Bergmann, Thaisa; Paggi, Alessandro; Wang, Junfeng; Risaliti, Guido

2017-01-01

Due to its low density, moderate ionization, and weak kinematics, the narrow line region (NLR) of active galactic nuclei (AGN) provides poweful diagnostics for investigating AGN feedback. The CHandra Extended Emission line Region Survey (CHEERS) is the ultimate investigation into resolved feedback in the NLR. We present results from our CHEERS investigations of NGC 3393. By imaging extended X-ray line emission of NGC 3393 with Chandra and optical line emission with Hubble's narrow-band filters, we are able to map out the simultaneous impact of photoionization, jets and an AGN disk-wind. When resolved on scales of ~10s of parsecs, the NLR of NGC 3393 shows a complex multi-component medium. Diagnostic line mapping indicates a Low-ionization Emmision Line Region (LINER) cocoon surrounding the outflow-evacuated cavities (in optical) and surrounding the supports the presence of collisional plasma (in X-rays). These physically distinct constituent regions can only be resolved by the high-resolution imaging that Chandra and HST enable.

Detection of breast surgical margins with optical coherence tomography imaging: a concept evaluation study.

PubMed

Savastru, Dan; Chang, Ernest W; Miclos, Sorin; Pitman, Martha B; Patel, Ankit; Iftimia, Nicusor

2014-05-01

This study aimed to evaluate the concept of using high-resolution optical coherence tomography (OCT) imaging to rapidly assess surgical specimens and determine if cancer positive margins were left behind in the surgical bed. A mouse model of breast cancer was used in this study. Surgical specimens from 30 animals were investigated with OCT and automated interpretation of the OCT images was performed and tested against histopathology findings. Specimens from 10 animals were used to build a training set of OCT images, while the remaining 20 specimens were used for a validation set of images. The validation study showed that automated interpretation of OCT images can differentiate tissue types and detect cancer positive margins with at least 81% sensitivity and 89% specificity. The findings of this pilot study suggest that OCT imaging of surgical specimens and automated interpretation of OCT data may enable in the future real-time feedback to the surgeon about margin status in patients with breast cancer, and potentially with other types of cancers. Currently, such feedback is not provided and if positive margins are left behind, patients have to undergo another surgical procedure. Therefore, this approach can have a potentially high impact on breast surgery outcome.

Image-guided feedback for ophthalmic microsurgery using multimodal intraoperative swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography

NASA Astrophysics Data System (ADS)

Li, Jianwei D.; Malone, Joseph D.; El-Haddad, Mohamed T.; Arquitola, Amber M.; Joos, Karen M.; Patel, Shriji N.; Tao, Yuankai K.

2017-02-01

Surgical interventions for ocular diseases involve manipulations of semi-transparent structures in the eye, but limited visualization of these tissue layers remains a critical barrier to developing novel surgical techniques and improving clinical outcomes. We addressed limitations in image-guided ophthalmic microsurgery by using microscope-integrated multimodal intraoperative swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography (iSS-SESLO-OCT). We previously demonstrated in vivo human ophthalmic imaging using SS-SESLO-OCT, which enabled simultaneous acquisition of en face SESLO images with every OCT cross-section. Here, we integrated our new 400 kHz iSS-SESLO-OCT, which used a buffered Axsun 1060 nm swept-source, with a surgical microscope and TrueVision stereoscopic viewing system to provide image-based feedback. In vivo human imaging performance was demonstrated on a healthy volunteer, and simulated surgical maneuvers were performed in ex vivo porcine eyes. Denselysampled static volumes and volumes subsampled at 10 volumes-per-second were used to visualize tissue deformations and surgical dynamics during corneal sweeps, compressions, and dissections, and retinal sweeps, compressions, and elevations. En face SESLO images enabled orientation and co-registration with the widefield surgical microscope view while OCT imaging enabled depth-resolved visualization of surgical instrument positions relative to anatomic structures-of-interest. TrueVision heads-up display allowed for side-by-side viewing of the surgical field with SESLO and OCT previews for real-time feedback, and we demonstrated novel integrated segmentation overlays for augmented-reality surgical guidance. Integration of these complementary imaging modalities may benefit surgical outcomes by enabling real-time intraoperative visualization of surgical plans, instrument positions, tissue deformations, and image-based surrogate biomarkers correlated with completion of surgical goals.

The jet/wind outflow in Centaurus A: a local laboratory for AGN feedback

NASA Astrophysics Data System (ADS)

McKinley, B.; Tingay, S. J.; Carretti, E.; Ellis, S.; Bland-Hawthorn, J.; Morganti, R.; Line, J.; McDonald, M.; Veilleux, S.; Wahl Olsen, R.; Sidonio, M.; Ekers, R.; Offringa, A. R.; Procopio, P.; Pindor, B.; Wayth, R. B.; Hurley-Walker, N.; Bernardi, G.; Gaensler, B. M.; Haverkorn, M.; Kesteven, M.; Poppi, S.; Staveley-Smith, L.

2018-03-01

We present new radio and optical images of the nearest radio galaxy Centaurus A and its host galaxy NGC 5128. We focus our investigation on the northern transition region, where energy is transported from the ˜5 kpc (˜5 arcmin) scales of the northern inner lobe (NIL) to the ˜30 kpc (˜30 arcmin) scales of the northern middle lobe (NML). Our Murchison Widefield Array observations at 154 MHz and our Parkes radio telescope observations at 2.3 GHz show diffuse radio emission connecting the NIL to the NML, in agreement with previous Australia Telescope Compact Array observations at 1.4 GHz. Comparison of these radio data with our wide-field optical emission-line images show the relationship between the NML radio emission and the ionized filaments that extend north from the NIL, and reveal a new ionized filament to the east, possibly associated with a galactic wind. Our deep optical images show clear evidence for a bipolar outflow from the central galaxy extending to intermediate scales, despite the non-detection of a southern radio counterpart to the NML. Thus, our observational overview of Centaurus A reveals a number of features proposed to be associated with active galactic nucleus feedback mechanisms, often cited as likely to have significant effects in galaxy evolution models. As one of the closest galaxies to us, Centaurus A therefore provides a unique laboratory to examine feedback mechanisms in detail.

Real-time optical fiber digital speckle pattern interferometry for industrial applications

NASA Astrophysics Data System (ADS)

Chan, Robert K.; Cheung, Y. M.; Lo, C. H.; Tam, T. K.

1997-03-01

There is current interest, especially in the industrial sector, to use the digital speckle pattern interferometry (DSPI) technique to measure surface stress. Indeed, many publications in the subject are evident of the growing interests in the field. However, to bring the technology to industrial use requires the integration of several emerging technologies, viz. optics, feedback control, electronics, imaging processing and digital signal processing. Due to the highly interdisciplinary nature of the technique, successful implementation and development require expertise in all of the fields. At Baptist University, under the funding of a major industrial grant, we are developing the technology for the industrial sector. Our system fully exploits optical fibers and diode lasers in the design to enable practical and rugged systems suited for industrial applications. Besides the development in optics, we have broken away from the reliance of a microcomputer PC platform for both image capture and processing, and have developed a digital signal processing array system that can handle simultaneous and independent image capture/processing with feedback control. The system, named CASPA for 'cascadable architecture signal processing array,' is a third generation development system that utilizes up to 7 digital signal processors has proved to be a very powerful system. With our CASPA we are now in a better position to developing novel optical measurement systems for industrial application that may require different measurement systems to operate concurrently and requiring information exchange between the systems. Applications in mind such as simultaneous in-plane and out-of-plane DSPI image capture/process, vibrational analysis with interactive DSPI and phase shifting control of optical systems are a few good examples of the potentials.

Computational adaptive optics for broadband interferometric tomography of tissues and cells

NASA Astrophysics Data System (ADS)

Adie, Steven G.; Mulligan, Jeffrey A.

2016-03-01

Adaptive optics (AO) can shape aberrated optical wavefronts to physically restore the constructive interference needed for high-resolution imaging. With access to the complex optical field, however, many functions of optical hardware can be achieved computationally, including focusing and the compensation of optical aberrations to restore the constructive interference required for diffraction-limited imaging performance. Holography, which employs interferometric detection of the complex optical field, was developed based on this connection between hardware and computational image formation, although this link has only recently been exploited for 3D tomographic imaging in scattering biological tissues. This talk will present the underlying imaging science behind computational image formation with optical coherence tomography (OCT) -- a beam-scanned version of broadband digital holography. Analogous to hardware AO (HAO), we demonstrate computational adaptive optics (CAO) and optimization of the computed pupil correction in 'sensorless mode' (Zernike polynomial corrections with feedback from image metrics) or with the use of 'guide-stars' in the sample. We discuss the concept of an 'isotomic volume' as the volumetric extension of the 'isoplanatic patch' introduced in astronomical AO. Recent CAO results and ongoing work is highlighted to point to the potential biomedical impact of computed broadband interferometric tomography. We also discuss the advantages and disadvantages of HAO vs. CAO for the effective shaping of optical wavefronts, and highlight opportunities for hybrid approaches that synergistically combine the unique advantages of hardware and computational methods for rapid volumetric tomography with cellular resolution.

Feedback mechanism for smart nozzles and nebulizers

DOEpatents

Montaser, Akbar [Potomac, MD; Jorabchi, Kaveh [Arlington, VA; Kahen, Kaveh [Kleinburg, CA

2009-01-27

Nozzles and nebulizers able to produce aerosol with optimum and reproducible quality based on feedback information obtained using laser imaging techniques. Two laser-based imaging techniques based on particle image velocimetry (PTV) and optical patternation map and contrast size and velocity distributions for indirect and direct pneumatic nebulizations in plasma spectrometry. Two pulses from thin laser sheet with known time difference illuminate droplets flow field. Charge coupled device (CCL)) captures scattering of laser light from droplets, providing two instantaneous particle images. Pointwise cross-correlation of corresponding images yields two-dimensional velocity map of aerosol velocity field. For droplet size distribution studies, solution is doped with fluorescent dye and both laser induced florescence (LIF) and Mie scattering images are captured simultaneously by two CCDs with the same field of view. Ratio of LIF/Mie images provides relative droplet size information, then scaled by point calibration method via phase Doppler particle analyzer.

Fast terahertz imaging using a quantum cascade amplifier

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ren, Yuan, E-mail: yr235@cam.ac.uk; Wallis, Robert; Jessop, David Stephen

2015-07-06

A terahertz (THz) imaging scheme based on the effect of self-mixing in a 2.9 THz quantum cascade (QC) amplifier has been demonstrated. By coupling an antireflective-coated silicon lens to the facet of a QC laser, with no external optical feedback, the laser mirror losses are enhanced to fully suppress lasing action, creating a THz QC amplifier. The addition of reflection from an external target to the amplifier creates enough optical feedback to initiate lasing action and the resulting emission enhances photon-assisted transport, which in turn reduces the voltage across the device. At the peak gain point, the maximum photon densitymore » coupled back leads to a prominent self-mixing effect in the QC amplifier, leading to a high sensitivity, with a signal to noise ratio up to 55 dB, along with a fast data acquisition speed of 20 000 points per second.« less

Near-infrared image-guided laser ablation of artificial caries lesions.

PubMed

Tao, You-Chen; Fan, Kenneth; Fried, Daniel

2007-01-01

Laser removal of dental hard tissue can be combined with optical, spectral or acoustic feedback systems to selectively ablate dental caries and restorative materials. Near-infrared (NIR) imaging has considerable potential for the optical discrimination of sound and demineralized tissue. The objective of this study was to test the hypothesis that two-dimensional NIR images of demineralized tooth surfaces can be used to guide CO(2) laser ablation for the selective removal of artificial caries lesions. Highly patterned artificial lesions were produced by submerging 5 × 5 mm(2) bovine enamel samples in demineralized solution for a 9-day period while sound areas were protected with acid resistant varnish. NIR imaging and polarization sensitive optical coherence tomography (PS-OCT) were used to acquire depth-resolved images at a wavelength of 1310-nm. An imaging processing module was developed to analyze the NIR images and to generate optical maps. The optical maps were used to control a CO(2) laser for the selective removal of the lesions at a uniform depth. This experiment showed that the patterned artificial lesions were removed selectively using the optical maps with minimal damage to sound enamel areas. Post-ablation NIR and PS-OCT imaging confirmed that demineralized areas were removed while sound enamel was conserved. This study successfully demonstrated that near-IR imaging can be integrated with a CO(2) laser ablation system for the selective removal of dental caries.

Near-infrared image-guided laser ablation of artificial caries lesions

PubMed Central

Tao, You-Chen; Fan, Kenneth; Fried, Daniel

2012-01-01

Laser removal of dental hard tissue can be combined with optical, spectral or acoustic feedback systems to selectively ablate dental caries and restorative materials. Near-infrared (NIR) imaging has considerable potential for the optical discrimination of sound and demineralized tissue. The objective of this study was to test the hypothesis that two–dimensional NIR images of demineralized tooth surfaces can be used to guide CO2 laser ablation for the selective removal of artificial caries lesions. Highly patterned artificial lesions were produced by submerging 5 × 5 mm2 bovine enamel samples in demineralized solution for a 9-day period while sound areas were protected with acid resistant varnish. NIR imaging and polarization sensitive optical coherence tomography (PS-OCT) were used to acquire depth-resolved images at a wavelength of 1310-nm. An imaging processing module was developed to analyze the NIR images and to generate optical maps. The optical maps were used to control a CO2 laser for the selective removal of the lesions at a uniform depth. This experiment showed that the patterned artificial lesions were removed selectively using the optical maps with minimal damage to sound enamel areas. Post-ablation NIR and PS-OCT imaging confirmed that demineralized areas were removed while sound enamel was conserved. This study successfully demonstrated that near-IR imaging can be integrated with a CO2 laser ablation system for the selective removal of dental caries. PMID:22866210

Near-infrared image-guided laser ablation of artificial caries lesions

NASA Astrophysics Data System (ADS)

Tao, You-Chen; Fan, Kenneth; Fried, Daniel

2007-02-01

Laser removal of dental hard tissue can be combined with optical, spectral or acoustic feedback systems to selectively ablate dental caries and restorative materials. Near-infrared (NIR) imaging has considerable potential for the optical discrimination of sound and demineralized tissue. The objective of this study was to test the hypothesis that two-dimensional NIR images of demineralized tooth surfaces can be used to guide CO II laser ablation for the selective removal of artificial caries lesions. Highly patterned artificial lesions were produced by submerging 5 x 5 mm2 bovine enamel samples in demineralized solution for a 9-day period while sound areas were protected with acid resistant varnish. NIR imaging and polarization sensitive optical coherence tomography (PS-OCT) were used to acquire depth-resolved images at a wavelength of 1310-nm. An imaging processing module was developed to analyze the NIR images and to generate optical maps. The optical maps were used to control a CO II laser for the selective removal of the lesions at a uniform depth. This experiment showed that the patterned artificial lesions were removed selectively using the optical maps with minimal damage to sound enamel areas. Post-ablation NIR and PS-OCT imaging confirmed that demineralized areas were removed while sound enamel was conserved. This study successfully demonstrated that near-IR imaging can be integrated with a CO II laser ablation system for the selective removal of dental caries.

In-situ high-resolution visualization of laser-induced periodic nanostructures driven by optical feedback.

PubMed

Aguilar, Alberto; Mauclair, Cyril; Faure, Nicolas; Colombier, Jean-Philippe; Stoian, Razvan

2017-11-28

Optical feedback is often evoked in laser-induced periodic nanostructures. Visualizing the coupling between surfaces and light requires highly-resolved imaging methods. We propose in-situ structured-illumination-microscopy to observe ultrafast-laser-induced nanostructures during fabrication on metallic glass surfaces. This resolves the pulse-to-pulse development of periodic structures on a single irradiation site and indicates the optical feedback on surface topographies. Firstly, the quasi-constancy of the ripples pattern and the reinforcement of the surface relief with the same spatial positioning indicates a phase-locking mechanism that stabilizes and amplifies the ordered corrugation. Secondly, on sites with uncorrelated initial corrugation, we observe ripple patterns spatially in-phase. These feedback aspects rely on the electromagnetic interplay between the laser pulse and the surface relief, stabilizing the pattern in period and position. They are critically dependent on the space-time coherence of the exciting pulse. This suggests a modulation of energy according to the topography of the surface with a pattern phase imposed by the driving pulse. A scattering and interference model for ripple formation on surfaces supports the experimental observations. This relies on self-phase-stabilized far-field interaction between surface scattered wavelets and the incoming pulse front.

A Surface-Coupled Optical Trap with 1-bp Precision via Active Stabilization

PubMed Central

Okoniewski, Stephen R.; Carter, Ashley R.; Perkins, Thomas T.

2017-01-01

Optical traps can measure bead motions with Å-scale precision. However, using this level of precision to infer 1-bp motion of molecular motors along DNA is difficult, since a variety of noise sources degrade instrumental stability. In this chapter, we detail how to improve instrumental stability by (i) minimizing laser pointing, mode, polarization, and intensity noise using an acousto-optical-modulator mediated feedback loop and (ii) minimizing sample motion relative to the optical trap using a 3-axis piezo-electric-stage mediated feedback loop. These active techniques play a critical role in achieving a surface stability of 1 Å in 3D over tens of seconds and a 1-bp stability and precision in a surface-coupled optical trap over a broad bandwidth (Δf = 0.03–2 Hz) at low force (6 pN). These active stabilization techniques can also aid other biophysical assays that would benefit from improved laser stability and/or Å-scale sample stability, such as atomic force microscopy and super-resolution imaging. PMID:27844426

Adaptive optics using a MEMS deformable mirror for a segmented mirror telescope

NASA Astrophysics Data System (ADS)

Miyamura, Norihide

2017-09-01

For small satellite remote sensing missions, a large aperture telescope more than 400mm is required to realize less than 1m GSD observations. However, it is difficult or expensive to realize the large aperture telescope using a monolithic primary mirror with high surface accuracy. A segmented mirror telescope should be studied especially for small satellite missions. Generally, not only high accuracy of optical surface but also high accuracy of optical alignment is required for large aperture telescopes. For segmented mirror telescopes, the alignment is more difficult and more important. For conventional systems, the optical alignment is adjusted before launch to achieve desired imaging performance. However, it is difficult to adjust the alignment for large sized optics in high accuracy. Furthermore, thermal environment in orbit and vibration in a launch vehicle cause the misalignments of the optics. We are developing an adaptive optics system using a MEMS deformable mirror for an earth observing remote sensing sensor. An image based adaptive optics system compensates the misalignments and wavefront aberrations of optical elements using the deformable mirror by feedback of observed images. We propose the control algorithm of the deformable mirror for a segmented mirror telescope by using of observed image. The numerical simulation results and experimental results show that misalignment and wavefront aberration of the segmented mirror telescope are corrected and image quality is improved.

Photoacoustics with coherent light

PubMed Central

Bossy, Emmanuel; Gigan, Sylvain

2016-01-01

Since its introduction in the mid-nineties, photoacoustic imaging of biological tissue has been one of the fastest growing biomedical imaging modality, and its basic principles are now considered as well established. In particular, light propagation in photoacoustic imaging is generally considered from the perspective of transport theory. However, recent breakthroughs in optics have shown that coherent light propagating through optically scattering medium could be manipulated towards novel imaging approaches. In this article, we first provide an introduction to the relevant concepts in the field, and then review the recent works showing that it is possible to exploit the coherence of light in conjunction with photoacoustics. We illustrate how the photoacoustic effect can be used as a powerful feedback mechanism for optical wavefront shaping in complex media, and conversely show how the coherence of light can be exploited to enhance photoacoustic imaging, for instance in terms of spatial resolution or for designing minimally invasive endoscopic devices. Finally, we discuss the current challenges and perspectives down the road towards practical applications in the field of photoacoustic imaging. PMID:27069874

OSM-Classic : An optical imaging technique for accurately determining strain

NASA Astrophysics Data System (ADS)

Aldrich, Daniel R.; Ayranci, Cagri; Nobes, David S.

OSM-Classic is a program designed in MATLAB® to provide a method of accurately determining strain in a test sample using an optical imaging technique. Measuring strain for the mechanical characterization of materials is most commonly performed with extensometers, LVDT (linear variable differential transistors), and strain gauges; however, these strain measurement methods suffer from their fragile nature and it is not particularly easy to attach these devices to the material for testing. To alleviate these potential problems, an optical approach that does not require contact with the specimen can be implemented to measure the strain. OSM-Classic is a software that interrogates a series of images to determine elongation in a test sample and hence, strain of the specimen. It was designed to provide a graphical user interface that includes image processing with a dynamic region of interest. Additionally, the stain is calculated directly while providing active feedback during the processing.

Deep Chandra , HST-COS, and megacam observations of the Phoenix cluster: Extreme star formation and AGN feedback on hundred kiloparsec scales

DOE PAGES

McDonald, Michael; McNamara, Brian R.; Perimeter Institute for Theoretical Physics, Waterloo; ...

2015-09-28

In this study, we present new ultraviolet, optical, and X-ray data on the Phoenix galaxy cluster (SPT-CLJ2344-4243). Deep optical imaging reveals previously undetected filaments of star formation, extending to radii of ~50–100 kpc in multiple directions. Combined UV-optical spectroscopy of the central galaxy reveals a massive (2 × 10 9 M ⊙), young (~4.5 Myr) population of stars, consistent with a time-averaged star formation rate of 610 ± 50 M ⊙ yr –1. We report a strong detection of O vi λλ1032,1038, which appears to originate primarily in shock-heated gas, but may contain a substantial contribution (>1000 M ⊙ yrmore » –1) from the cooling intracluster medium (ICM). We confirm the presence of deep X-ray cavities in the inner ~10 kpc, which are among the most extreme examples of radio-mode feedback detected to date, implying jet powers of 2 – 7 × 10 45 erg s –1. We provide evidence that the active galactic nucleus inflating these cavities may have only recently transitioned from "quasar-mode" to "radio-mode," and may currently be insufficient to completely offset cooling. A model-subtracted residual X-ray image reveals evidence for prior episodes of strong radio-mode feedback at radii of ~100 kpc, with extended "ghost" cavities indicating a prior epoch of feedback roughly 100 Myr ago. This residual image also exhibits significant asymmetry in the inner ~200 kpc (0.15R 500), reminiscent of infalling cool clouds, either due to minor mergers or fragmentation of the cooling ICM. Taken together, these data reveal a rapidly evolving cool core which is rich with structure (both spatially and in temperature), is subject to a variety of highly energetic processes, and yet is cooling rapidly and forming stars along thin, narrow filaments.« less

Semiconductor ring lasers subject to both on-chip filtered optical feedback and external conventional optical feedback

NASA Astrophysics Data System (ADS)

Khoder, Mulham; Van der Sande, Guy; Danckaert, Jan; Verschaffelt, Guy

2016-05-01

It is well known that the performance of semiconductor lasers is very sensitive to external optical feedback. This feedback can lead to changes in lasing characteristics and a variety of dynamical effects including chaos and coherence collapse. One way to avoid this external feedback is by using optical isolation, but these isolators and their packaging will increase the cost of the total system. Semiconductor ring lasers nowadays are promising sources in photonic integrated circuits because they do not require cleaved facets or mirrors to form a laser cavity. Recently, some of us proposed to combine semiconductor ring lasers with on chip filtered optical feedback to achieve tunable lasers. The feedback is realized by employing two arrayed waveguide gratings to split/recombine light into different wavelength channels. Semiconductor optical amplifier gates are used to control the feedback strength. In this work, we investigate how such lasers with filtered feedback are influenced by an external conventional optical feedback. The experimental results show intensity fluctuations in the time traces in both the clockwise and counterclockwise directions due to the conventional feedback. We quantify the strength of the conventional feedback induced dynamics be extracting the standard deviation of the intensity fluctuations in the time traces. By using filtered feedback, we can shift the onset of the conventional feedback induced dynamics to larger values of the feedback rate [ Khoder et al, IEEE Photon. Technol. Lett. DOI: 10.1109/LPT.2016.2522184]. The on-chip filtered optical feedback thus makes the semiconductor ring laser less senstive to the effect of (long) conventional optical feedback. We think these conclusions can be extended to other types of lasers.

DOE Office of Scientific and Technical Information (OSTI.GOV)

McDonald, Michael; McNamara, Brian R.; Perimeter Institute for Theoretical Physics, Waterloo

In this study, we present new ultraviolet, optical, and X-ray data on the Phoenix galaxy cluster (SPT-CLJ2344-4243). Deep optical imaging reveals previously undetected filaments of star formation, extending to radii of ~50–100 kpc in multiple directions. Combined UV-optical spectroscopy of the central galaxy reveals a massive (2 × 10 9 M ⊙), young (~4.5 Myr) population of stars, consistent with a time-averaged star formation rate of 610 ± 50 M ⊙ yr –1. We report a strong detection of O vi λλ1032,1038, which appears to originate primarily in shock-heated gas, but may contain a substantial contribution (>1000 M ⊙ yrmore » –1) from the cooling intracluster medium (ICM). We confirm the presence of deep X-ray cavities in the inner ~10 kpc, which are among the most extreme examples of radio-mode feedback detected to date, implying jet powers of 2 – 7 × 10 45 erg s –1. We provide evidence that the active galactic nucleus inflating these cavities may have only recently transitioned from "quasar-mode" to "radio-mode," and may currently be insufficient to completely offset cooling. A model-subtracted residual X-ray image reveals evidence for prior episodes of strong radio-mode feedback at radii of ~100 kpc, with extended "ghost" cavities indicating a prior epoch of feedback roughly 100 Myr ago. This residual image also exhibits significant asymmetry in the inner ~200 kpc (0.15R 500), reminiscent of infalling cool clouds, either due to minor mergers or fragmentation of the cooling ICM. Taken together, these data reveal a rapidly evolving cool core which is rich with structure (both spatially and in temperature), is subject to a variety of highly energetic processes, and yet is cooling rapidly and forming stars along thin, narrow filaments.« less

Large depth high-precision FMCW tomography using a distributed feedback laser array

NASA Astrophysics Data System (ADS)

DiLazaro, Thomas; Nehmetallah, George

2018-02-01

Swept-source optical coherence tomography (SS-OCT) has been widely employed in the medical industry for the high resolution imaging of subsurface biological structures. SS-OCT typically exhibits axial resolutions on the order of tens of microns at speeds of hundreds of kilohertz. Using the same coherent heterodyne detection technique, frequency modulated continuous wave (FMCW) ladar has been used for highly precise ranging for distances up to kilometers. Distributed feedback lasers (DFBs) have been used as a simple and inexpensive source for FMCW ranging. Here, we use a bandwidth-combined DFB array for sub-surface volume imaging at a 27 μm axial resolution over meters of distance. 2D and 3D tomographic images of several semi-transparent and diffuse objects at distances up to 10 m will be presented.

Assessment of Sentinel Node Biopsies With Full-Field Optical Coherence Tomography.

PubMed

Grieve, Kate; Mouslim, Karima; Assayag, Osnath; Dalimier, Eugénie; Harms, Fabrice; Bruhat, Alexis; Boccara, Claude; Antoine, Martine

2016-04-01

Current techniques for the intraoperative analysis of sentinel lymph nodes during breast cancer surgery present drawbacks such as time and tissue consumption. Full-field optical coherence tomography is a novel noninvasive, high-resolution, fast imaging technique. This study investigated the use of full-field optical coherence tomography as an alternative technique for the intraoperative analysis of sentinel lymph nodes. Seventy-one axillary lymph nodes from 38 patients at Tenon Hospital were imaged minutes after excision with full-field optical coherence tomography in the pathology laboratory, before being handled for histological analysis. A pathologist performed a blind diagnosis (benign/malignant), based on the full-field optical coherence tomography images alone, which resulted in a sensitivity of 92% and a specificity of 83% (n = 65 samples). Regular feedback was given during the blind diagnosis, with thorough analysis of the images, such that features of normal and suspect nodes were identified in the images and compared with histology. A nonmedically trained imaging expert also performed a blind diagnosis aided by the reading criteria defined by the pathologist, which resulted in 85% sensitivity and 90% specificity (n = 71 samples). The number of false positives of the pathologist was reduced by 3 in a second blind reading a few months later. These results indicate that following adequate training, full-field optical coherence tomography can be an effective noninvasive diagnostic tool for extemporaneous sentinel node biopsy qualification. © The Author(s) 2015.

Feedback from visual cortical area 7 to areas 17 and 18 in cats: How neural web is woven during feedback.

PubMed

Yang, X; Ding, H; Lu, J

2016-01-15

To investigate the feedback effect from area 7 to areas 17 and 18, intrinsic signal optical imaging combined with pharmacological, morphological methods and functional magnetic resonance imaging (fMRI) was employed. A spatial frequency-dependent decrease in response amplitude of orientation maps was observed in areas 17 and 18 when area 7 was inactivated by a local injection of GABA, or by a lesion induced by liquid nitrogen freezing. The pattern of orientation maps of areas 17 and 18 after the inactivation of area 7, if they were not totally blurred, paralleled the normal one. In morphological experiments, after one point at the shallow layers within the center of the cat's orientation column of area 17 was injected electrophoretically with HRP (horseradish peroxidase), three sequential patches in layers 1, 2 and 3 of area 7 were observed. Employing fMRI it was found that area 7 feedbacks mainly to areas 17 and 18 on ipsilateral hemisphere. Therefore, our conclusions are: (1) feedback from area 7 to areas 17 and 18 is spatial frequency modulated; (2) feedback from area 7 to areas 17 and 18 occurs mainly ipsilaterally; (3) histological feedback pattern from area 7 to area 17 is weblike. Copyright © 2015 IBRO. Published by Elsevier Ltd. All rights reserved.

Biological applications of near-field scanning optical microscopy

NASA Astrophysics Data System (ADS)

Moers, Marco H. P.; Ruiter, A. G. T.; Jalocha, Alain; van Hulst, Niko F.; Kalle, W. H. J.; Wiegant, J. C. A. G.; Raap, A. K.

1995-09-01

Near-field Scanning Optical Microscopy (NSOM) is a true optical microscopic technique allowing fluorescence, absorption, reflection and polarization contrast with the additional advantage of nanometer lateral resolution, unlimited by diffraction and operation at ambient conditions. NSOM based on metal coated adiabatically tapered fibers, combined with shear force feedback and operated in illumination mode, has proven to be the most powerful NSOM arrangement, because of its true localization of the optical interaction, its various optical contrast possibilities and its sensitivity down to the single molecular level. In this paper applications of `aperture' NSOM to Fluorescence In Situ Hybridization of human metaphase chromosomes are presented, where the localized fluorescence allows to identify specific DNA sequences. All images are accompanied by the simultaneously acquired force image, enabling direct comparison of the optical contrast with the sample topography on nanometer scale, far beyond the diffraction limit. Thus the unique combination of high resolution, specific optical contrast and ambient operation offers many new direction possibilities in biological studies.

The Extended-Image Tracking Technique Based on the Maximum Likelihood Estimation

NASA Technical Reports Server (NTRS)

Tsou, Haiping; Yan, Tsun-Yee

2000-01-01

This paper describes an extended-image tracking technique based on the maximum likelihood estimation. The target image is assume to have a known profile covering more than one element of a focal plane detector array. It is assumed that the relative position between the imager and the target is changing with time and the received target image has each of its pixels disturbed by an independent additive white Gaussian noise. When a rotation-invariant movement between imager and target is considered, the maximum likelihood based image tracking technique described in this paper is a closed-loop structure capable of providing iterative update of the movement estimate by calculating the loop feedback signals from a weighted correlation between the currently received target image and the previously estimated reference image in the transform domain. The movement estimate is then used to direct the imager to closely follow the moving target. This image tracking technique has many potential applications, including free-space optical communications and astronomy where accurate and stabilized optical pointing is essential.

Integrative advances for OCT-guided ophthalmic surgery and intraoperative OCT: microscope integration, surgical instrumentation, and heads-up display surgeon feedback.

PubMed

Ehlers, Justis P; Srivastava, Sunil K; Feiler, Daniel; Noonan, Amanda I; Rollins, Andrew M; Tao, Yuankai K

2014-01-01

To demonstrate key integrative advances in microscope-integrated intraoperative optical coherence tomography (iOCT) technology that will facilitate adoption and utilization during ophthalmic surgery. We developed a second-generation prototype microscope-integrated iOCT system that interfaces directly with a standard ophthalmic surgical microscope. Novel features for improved design and functionality included improved profile and ergonomics, as well as a tunable lens system for optimized image quality and heads-up display (HUD) system for surgeon feedback. Novel material testing was performed for potential suitability for OCT-compatible instrumentation based on light scattering and transmission characteristics. Prototype surgical instruments were developed based on material testing and tested using the microscope-integrated iOCT system. Several surgical maneuvers were performed and imaged, and surgical motion visualization was evaluated with a unique scanning and image processing protocol. High-resolution images were successfully obtained with the microscope-integrated iOCT system with HUD feedback. Six semi-transparent materials were characterized to determine their attenuation coefficients and scatter density with an 830 nm OCT light source. Based on these optical properties, polycarbonate was selected as a material substrate for prototype instrument construction. A surgical pick, retinal forceps, and corneal needle were constructed with semi-transparent materials. Excellent visualization of both the underlying tissues and surgical instrument were achieved on OCT cross-section. Using model eyes, various surgical maneuvers were visualized, including membrane peeling, vessel manipulation, cannulation of the subretinal space, subretinal intraocular foreign body removal, and corneal penetration. Significant iterative improvements in integrative technology related to iOCT and ophthalmic surgery are demonstrated.

A Surface-Coupled Optical Trap with 1-bp Precision via Active Stabilization.

PubMed

Okoniewski, Stephen R; Carter, Ashley R; Perkins, Thomas T

2017-01-01

Optical traps can measure bead motions with Å-scale precision. However, using this level of precision to infer 1-bp motion of molecular motors along DNA is difficult, since a variety of noise sources degrade instrumental stability. In this chapter, we detail how to improve instrumental stability by (1) minimizing laser pointing, mode, polarization, and intensity noise using an acousto-optical-modulator mediated feedback loop and (2) minimizing sample motion relative to the optical trap using a three-axis piezo-electric-stage mediated feedback loop. These active techniques play a critical role in achieving a surface stability of 1 Å in 3D over tens of seconds and a 1-bp stability and precision in a surface-coupled optical trap over a broad bandwidth (Δf = 0.03-2 Hz) at low force (6 pN). These active stabilization techniques can also aid other biophysical assays that would benefit from improved laser stability and/or Å-scale sample stability, such as atomic force microscopy and super-resolution imaging.

Panoramic optical-servoing for industrial inspection and repair

NASA Astrophysics Data System (ADS)

Sallinger, Christian; O'Leary, Paul; Retschnig, Alexander; Kammerhofer, Martin

2004-05-01

Recently specialized robots were introduced to perform the task of inspection and repair in large cylindrical structures such as ladles, melting furnaces and converters. This paper reports on the image processing system and optical servoing for one such a robot. A panoramic image of the vessels inner surface is produced by performing a coordinated robot motion and image acquisition. The level of projective distortion is minimized by acquiring a high density of images. Normalized phase correlation calculated via the 2D Fourier transform is used to calculate the shift between the single images. The narrow strips from the dense image map are then stitched together to build the panorama. The mapping between the panoramic image and the positioning of the robot is established during the stitching of the images. This enables optical feedback. The robots operator can locate a defect on the surface by selecting the area of the image. Calculation of the forward and inverse kinematics enable the robot to automatically move to the location on the surface requiring repair. Experimental results using a standard 6R industrial robot have shown the full functionality of the system concept. Finally, were test measurements carried out successfully, in a ladle at a temperature of 1100° C.

An Investigation of the Application of Artificial Neural Networks to Adaptive Optics Imaging Systems

DTIC Science & Technology

1991-12-01

neural network and the feedforward neural network studied is the single layer perceptron artificial neural network . The recurrent artificial neural network input...features are the wavefront sensor slope outputs and neighboring actuator feedback commands. The feedforward artificial neural network input

Optical feedback-induced light modulation for fiber-based laser ablation.

PubMed

Kang, Hyun Wook

2014-11-01

Optical fibers have been used as a minimally invasive tool in various medical fields. However, due to excessive heat accumulation, the distal end of a fiber often suffers from severe melting or devitrification, leading to the eventual fiber failure during laser treatment. In order to minimize thermal damage at the fiber tip, an optical feedback sensor was developed and tested ex vivo. Porcine kidney tissue was used to evaluate the feasibility of optical feedback in terms of signal activation, ablation performance, and light transmission. Testing various signal thresholds demonstrated that 3 V was relatively appropriate to trigger the feedback sensor and to prevent the fiber deterioration during kidney tissue ablation. Based upon the development of temporal signal signatures, full contact mode rapidly activated the optical feedback sensor possibly due to heat accumulation. Modulated light delivery induced by optical feedback diminished ablation efficiency by 30% in comparison with no feedback case. However, long-term transmission results validated that laser ablation assisted with optical feedback was able to almost consistently sustain light delivery to the tissue as well as ablation efficiency. Therefore, an optical feedback sensor can be a feasible tool to protect optical fiber tips by minimizing debris contamination and delaying thermal damage process and to ensure more efficient and safer laser-induced tissue ablation.

An optical/digital processor - Hardware and applications

NASA Technical Reports Server (NTRS)

Casasent, D.; Sterling, W. M.

1975-01-01

A real-time two-dimensional hybrid processor consisting of a coherent optical system, an optical/digital interface, and a PDP-11/15 control minicomputer is described. The input electrical-to-optical transducer is an electron-beam addressed potassium dideuterium phosphate (KD2PO4) light valve. The requirements and hardware for the output optical-to-digital interface, which is constructed from modular computer building blocks, are presented. Initial experimental results demonstrating the operation of this hybrid processor in phased-array radar data processing, synthetic-aperture image correlation, and text correlation are included. The applications chosen emphasize the role of the interface in the analysis of data from an optical processor and possible extensions to the digital feedback control of an optical processor.

Low cost heads-up virtual reality (HUVR) with optical tracking and haptic feedback

NASA Astrophysics Data System (ADS)

Margolis, Todd; DeFanti, Thomas A.; Dawe, Greg; Prudhomme, Andrew; Schulze, Jurgen P.; Cutchin, Steve

2011-03-01

Researchers at the University of California, San Diego, have created a new, relatively low-cost augmented reality system that enables users to touch the virtual environment they are immersed in. The Heads-Up Virtual Reality device (HUVR) couples a consumer 3D HD flat screen TV with a half-silvered mirror to project any graphic image onto the user's hands and into the space surrounding them. With his or her head position optically tracked to generate the correct perspective view, the user maneuvers a force-feedback (haptic) device to interact with the 3D image, literally 'touching' the object's angles and contours as if it was a tangible physical object. HUVR can be used for training and education in structural and mechanical engineering, archaeology and medicine as well as other tasks that require hand-eye coordination. One of the most unique characteristics of HUVR is that a user can place their hands inside of the virtual environment without occluding the 3D image. Built using open-source software and consumer level hardware, HUVR offers users a tactile experience in an immersive environment that is functional, affordable and scalable.

Intraoperative optical coherence tomography: past, present, and future

PubMed Central

Ehlers, J P

2016-01-01

To provide an overview of the current state of intraoperative optical coherence tomography (OCT). Literature review of studies pertaining to intraoperative OCT examining both the technology aspects of the imaging platform and the current evidence for patient care. Over the last several years, there have been significant advances in integrative technology for intraoperative OCT. This has resulted in the development of multiple microscope-integrated systems and a rapidly expanding field of image-guided surgical care. Multiple studies have demonstrated the potential role for intraoperative OCT in facilitating surgeon understanding of the surgical environment, tissue configuration, and overall changes to anatomy. In fact, the PIONEER and DISCOVER studies, both demonstrated a potential significant percentage of cases that intraoperative OCT alters surgical decision-making in both anterior and posterior segment surgery. Current areas of exploration and development include OCT-compatible instrumentation, automated tracking, intraoperative OCT software platforms, and surgeon feedback/visualization platforms. Intraoperative OCT is an emerging technology that holds promise for enhancing the surgical care of both anterior segment and posterior segment conditions. Hurdles remain for adoption and widespread utilization, including cost, optimized feedback platforms, and more definitive value for individualized surgical care with image guidance. PMID:26681147

Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention

NASA Astrophysics Data System (ADS)

Huang, Yong; Song, Cheol; Liu, Xuan; Kang, Jin U.

2013-03-01

A motion-compensated hand-held common-path Fourier-domain optical coherence tomography imaging probe has been developed for image guided intervention during microsurgery. A hand-held prototype instrument was designed and fabricated by integrating an imaging fiber probe inside a stainless steel needle which is attached to the ceramic shaft of a piezoelectric motor housed in an aluminum handle. The fiber probe obtains A-scan images. The distance information was extracted from the A-scans to track the sample surface distance and a fixed distance was maintained by a feedback motor control which effectively compensated hand tremor and target movements in the axial direction. Graphical user interface, real-time data processing, and visualization based on a CPU-GPU hybrid programming architecture were developed and used in the implantation of this system. To validate the system, free-hand optical coherence tomography images using various samples were obtained. The system can be easily integrated into microsurgical tools and robotics for a wide range of clinical applications. Such tools could offer physicians the freedom to easily image sites of interest with reduced risk and higher image quality.

Impact of optical feedback on current-induced polarization behavior of 1550 nm vertical-cavity surface-emitting lasers.

PubMed

Deng, Tao; Wu, Zheng-Mao; Xie, Yi-Yuan; Wu, Jia-Gui; Tang, Xi; Fan, Li; Panajotov, Krassimir; Xia, Guang-Qiong

2013-06-01

Polarization switching (PS) between two orthogonal linearly polarized fundamental modes is experimentally observed in commercial free-running 1550 nm vertical-cavity surface-emitting lasers (VCSELs) (Raycan). The characteristics of this PS are strongly modified after introducing a polarization-preserved (PP) or polarization-orthogonal (PO) optical feedback. Under the case that the external cavity is approximately 30 cm, the PP optical feedback results in the PS point shifting toward a lower injection current, and the region within which the two polarization modes coexist is enlarged with the increase of the PP feedback strength. Under too-strong PP feedback levels, the PS disappears. The impact of PO optical feedback on VCSEL polarization behavior is quite similar to that of PP optical feedback, but larger feedback strength is needed to obtain similar results.

Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection

PubMed Central

Tummers, Willemieke S.; Warram, Jason M.; Tipirneni, Kiranya E.; Fengler, John; Jacobs, Paula; Shankar, Lalitha; Henderson, Lori; Ballard, Betsy; Pogue, Brian W.; Weichert, Jamey P.; Bouvet, Michael; Sorger, Jonathan; Contag, Christopher H.; Frangioni, John V.; Tweedle, Michael F.; Basilion, James P.; Gambhir, Sanjiv S.; Rosenthal, Eben L.

2017-01-01

Considerable advances in cancer-specific optical imaging have improved the precision of tumor resection. In comparison to traditional imaging modalities, this technology is unique in its ability to provide real-time feedback to the operating surgeon. Given the significant clinical implications of optical imaging, there is an urgent need to standardize surgical navigation tools and contrast agents to facilitate swift regulatory approval. Because fluorescence-enhanced surgery requires a combination of both device and drug, each may be developed in conjunction, or separately, which are important considerations in the approval process. This report is the result of a one-day meeting held on May 4, 2016 with officials from the National Cancer Institute, the FDA, members of the American Society of Image-Guided Surgery, and members of the World Molecular Imaging Society, which discussed consensus methods for FDA-directed human testing and approval of investigational optical imaging devices as well as contrast agents for surgical applications. The goal of this workshop was to discuss FDA approval requirements and the expectations for approval of these novel drugs and devices, packaged separately or in combination, within the context of optical surgical navigation. In addition, the workshop acted to provide clarity to the research community on data collection and trial design. Reported here are the specific discussion items and recommendations from this critical and timely meeting. PMID:28428283

Optical feedback structures and methods of making

DOEpatents

None

2014-11-18

An optical resonator can include an optical feedback structure disposed on a substrate, and a composite including a matrix including a chromophore. The composite disposed on the substrate and in optical communication with the optical feedback structure. The chromophore can be a semiconductor nanocrystal. The resonator can provide laser emission when excited.

An inexpensive programmable illumination microscope with active feedback.

PubMed

Tompkins, Nathan; Fraden, Seth

2016-02-01

We have developed a programmable illumination system capable of tracking and illuminating numerous objects simultaneously using only low-cost and reused optical components. The active feedback control software allows for a closed-loop system that tracks and perturbs objects of interest automatically. Our system uses a static stage where the objects of interest are tracked computationally as they move across the field of view allowing for a large number of simultaneous experiments. An algorithmically determined illumination pattern can be applied anywhere in the field of view with simultaneous imaging and perturbation using different colors of light to enable spatially and temporally structured illumination. Our system consists of a consumer projector, camera, 35-mm camera lens, and a small number of other optical and scaffolding components. The entire apparatus can be assembled for under $4,000.

Servo control of an optical trap.

PubMed

Wulff, Kurt D; Cole, Daniel G; Clark, Robert L

2007-08-01

A versatile optical trap has been constructed to control the position of trapped objects and ultimately to apply specified forces using feedback control. While the design, development, and use of optical traps has been extensive and feedback control has played a critical role in pushing the state of the art, few comprehensive examinations of feedback control of optical traps have been undertaken. Furthermore, as the requirements are pushed to ever smaller distances and forces, the performance of optical traps reaches limits. It is well understood that feedback control can result in both positive and negative effects in controlled systems. We give an analysis of the trapping limits as well as introducing an optical trap with a feedback control scheme that dramatically improves an optical trap's sensitivity at low frequencies.

Integrative Advances for OCT-Guided Ophthalmic Surgery and Intraoperative OCT: Microscope Integration, Surgical Instrumentation, and Heads-Up Display Surgeon Feedback

PubMed Central

Ehlers, Justis P.; Srivastava, Sunil K.; Feiler, Daniel; Noonan, Amanda I.; Rollins, Andrew M.; Tao, Yuankai K.

2014-01-01

Purpose To demonstrate key integrative advances in microscope-integrated intraoperative optical coherence tomography (iOCT) technology that will facilitate adoption and utilization during ophthalmic surgery. Methods We developed a second-generation prototype microscope-integrated iOCT system that interfaces directly with a standard ophthalmic surgical microscope. Novel features for improved design and functionality included improved profile and ergonomics, as well as a tunable lens system for optimized image quality and heads-up display (HUD) system for surgeon feedback. Novel material testing was performed for potential suitability for OCT-compatible instrumentation based on light scattering and transmission characteristics. Prototype surgical instruments were developed based on material testing and tested using the microscope-integrated iOCT system. Several surgical maneuvers were performed and imaged, and surgical motion visualization was evaluated with a unique scanning and image processing protocol. Results High-resolution images were successfully obtained with the microscope-integrated iOCT system with HUD feedback. Six semi-transparent materials were characterized to determine their attenuation coefficients and scatter density with an 830 nm OCT light source. Based on these optical properties, polycarbonate was selected as a material substrate for prototype instrument construction. A surgical pick, retinal forceps, and corneal needle were constructed with semi-transparent materials. Excellent visualization of both the underlying tissues and surgical instrument were achieved on OCT cross-section. Using model eyes, various surgical maneuvers were visualized, including membrane peeling, vessel manipulation, cannulation of the subretinal space, subretinal intraocular foreign body removal, and corneal penetration. Conclusions Significant iterative improvements in integrative technology related to iOCT and ophthalmic surgery are demonstrated. PMID:25141340

Optical Computations for Image Bandwidth Compression.

DTIC Science & Technology

1981-05-15

UnCl1 ed 3 ’ " * ~ SECURITY CLASSIFICA/ION OF TWIS PA E Doi&e, be,. Enteerdj’ . /j (I) RFRORT DOCUMENTATION PAGE EAPINSTRUCTIONS (I) ~tOT DCUMETATON...Bolling Air Force Base, D. C. 20332 . NME’/PG 14. MONITORING AGENCY NAME 8 AOORESS(/I dilletnt from Controlling Office) IS. SECURITY CLASS. (oI thi ,(il... SECURITY CL.ASS4FICATII_ TI.AGE(W7Ief Deja Entered)2 (3)25imulations.m f a!1 incoherent optical/ *1 video feedback processor.. * Unclassi fled

FRET imaging and in silico simulation: analysis of the signaling network of nerve growth factor-induced neuritogenesis.

PubMed

Nakamura, Takeshi; Aoki, Kazuhiro; Matsuda, Michiyuki

2008-08-01

Genetically encoded probes based on Förster resonance energy transfer (FRET) enable us to decipher spatiotemporal information encoded in complex tissues such as the brain. Firstly, this review focuses on FRET probes wherein both the donor and acceptor are fluorescence proteins and are incorporated into a single molecule, i.e. unimolecular probes. Advantages of these probes lie in their easy loading into cells, the simple acquisition of FRET images, and the clear evaluation of data. Next, we introduce our recent study which encompasses FRET imaging and in silico simulation. In nerve growth factor-induced neurite outgrowth in PC12 cells, we found positive and negative signaling feedback loops. We propose that these feedback loops determine neurite-budding sites. We would like to emphasize that it is now time to accelerate crossover research in neuroscience, optics, and computational biology.

Multimodal swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography at 400 kHz

NASA Astrophysics Data System (ADS)

El-Haddad, Mohamed T.; Joos, Karen M.; Patel, Shriji N.; Tao, Yuankai K.

2017-02-01

Multimodal imaging systems that combine scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) have demonstrated the utility of concurrent en face and volumetric imaging for aiming, eye tracking, bulk motion compensation, mosaicking, and contrast enhancement. However, this additional functionality trades off with increased system complexity and cost because both SLO and OCT generally require dedicated light sources, galvanometer scanners, relay and imaging optics, detectors, and control and digitization electronics. We previously demonstrated multimodal ophthalmic imaging using swept-source spectrally encoded SLO and OCT (SS-SESLO-OCT). Here, we present system enhancements and a new optical design that increase our SS-SESLO-OCT data throughput by >7x and field-of-view (FOV) by >4x. A 200 kHz 1060 nm Axsun swept-source was optically buffered to 400 kHz sweep-rate, and SESLO and OCT were simultaneously digitized on dual input channels of a 4 GS/s digitizer at 1.2 GS/s per channel using a custom k-clock. We show in vivo human imaging of the anterior segment out to the limbus and retinal fundus over a >40° FOV. In addition, nine overlapping volumetric SS-SESLO-OCT volumes were acquired under video-rate SESLO preview and guidance. In post-processing, all nine SESLO images and en face projections of the corresponding OCT volumes were mosaicked to show widefield multimodal fundus imaging with a >80° FOV. Concurrent multimodal SS-SESLO-OCT may have applications in clinical diagnostic imaging by enabling aiming, image registration, and multi-field mosaicking and benefit intraoperative imaging by allowing for real-time surgical feedback, instrument tracking, and overlays of computationally extracted image-based surrogate biomarkers of disease.

DOE Office of Scientific and Technical Information (OSTI.GOV)

McDonald, Michael; Bautz, Marshall W.; Miller, Eric D.

We present new ultraviolet, optical, and X-ray data on the Phoenix galaxy cluster (SPT-CLJ2344-4243). Deep optical imaging reveals previously undetected filaments of star formation, extending to radii of ∼50–100 kpc in multiple directions. Combined UV-optical spectroscopy of the central galaxy reveals a massive (2 × 10{sup 9} M{sub ⊙}), young (∼4.5 Myr) population of stars, consistent with a time-averaged star formation rate of 610 ± 50 M{sub ⊙} yr{sup −1}. We report a strong detection of O vi λλ1032,1038, which appears to originate primarily in shock-heated gas, but may contain a substantial contribution (>1000 M{sub ⊙} yr{sup −1}) from themore » cooling intracluster medium (ICM). We confirm the presence of deep X-ray cavities in the inner ∼10 kpc, which are among the most extreme examples of radio-mode feedback detected to date, implying jet powers of 2–7 × 10{sup 45} erg s{sup −1}. We provide evidence that the active galactic nucleus inflating these cavities may have only recently transitioned from “quasar-mode” to “radio-mode,” and may currently be insufficient to completely offset cooling. A model-subtracted residual X-ray image reveals evidence for prior episodes of strong radio-mode feedback at radii of ∼100 kpc, with extended “ghost” cavities indicating a prior epoch of feedback roughly 100 Myr ago. This residual image also exhibits significant asymmetry in the inner ∼200 kpc (0.15R{sub 500}), reminiscent of infalling cool clouds, either due to minor mergers or fragmentation of the cooling ICM. Taken together, these data reveal a rapidly evolving cool core which is rich with structure (both spatially and in temperature), is subject to a variety of highly energetic processes, and yet is cooling rapidly and forming stars along thin, narrow filaments.« less

Optical properties of acute kidney injury measured by quantitative phase imaging

PubMed Central

Ban, Sungbea; Min, Eunjung; Baek, Songyee; Kwon, Hyug Moo; Popescu, Gabriel

2018-01-01

The diagnosis of acute kidney disease (AKI) has been examined mainly by histology, immunohistochemistry and western blot. Though these approaches are widely accepted in the field, it has an inherent limitation due to the lack of high-throughput and quantitative information. For a better understanding of prognosis in AKI, we present a new approach using quantitative phase imaging combined with a wide-field scanning platform. Through the phase-delay information from the tissue, we were able to predict a stage of AKI based on various optical properties such as light scattering coefficient and anisotropy. These optical parameters quantify the deterioration process of the AKI model of tissue. Our device would be a very useful tool when it is required to deliver fast feedback of tissue pathology or when diseases are related to mechanical properties such as fibrosis. PMID:29541494

Wavefront sensorless adaptive optics temporal focusing-based multiphoton microscopy

PubMed Central

Chang, Chia-Yuan; Cheng, Li-Chung; Su, Hung-Wei; Hu, Yvonne Yuling; Cho, Keng-Chi; Yen, Wei-Chung; Xu, Chris; Dong, Chen Yuan; Chen, Shean-Jen

2014-01-01

Temporal profile distortions reduce excitation efficiency and image quality in temporal focusing-based multiphoton microscopy. In order to compensate the distortions, a wavefront sensorless adaptive optics system (AOS) was integrated into the microscope. The feedback control signal of the AOS was acquired from local image intensity maximization via a hill-climbing algorithm. The control signal was then utilized to drive a deformable mirror in such a way as to eliminate the distortions. With the AOS correction, not only is the axial excitation symmetrically refocused, but the axial resolution with full two-photon excited fluorescence (TPEF) intensity is also maintained. Hence, the contrast of the TPEF image of a R6G-doped PMMA thin film is enhanced along with a 3.7-fold increase in intensity. Furthermore, the TPEF image quality of 1μm fluorescent beads sealed in agarose gel at different depths is improved. PMID:24940539

A High Definition View of AGN Feedback: Chandra Imaging of Nearby Seyfert Galaxies

NASA Astrophysics Data System (ADS)

Wang, Junfeng; Fabbiano, G.; Risaliti, G.; Elvis, M.; Karovska, M.; Zezas, A.; Mundell, C. G.

2010-03-01

To improve the physics of AGN feedback, it is crucial to evaluate the true role of outflows on galaxy evolution observationally. I will present new results from Chandra spectral imaging of nearby Seyfert galaxies, which offer unique opportunities to examine feedback in action in much greater detail than at high redshift. Exploiting Chandra's highest possible resolution, we are able to study structures in NGC 4151 on spatial scales of 0.5 arcsec (30 pc), showing an extended X-ray morphology overall consistent with the optical NLR. We find that most of the NLR clouds in NGC 4151 have [OIII] to soft X-ray ratio consistent with the values observed in NLRs of some Seyfert 2 galaxies, which indicates a uniform ionization parameter even at large radii. We examine various X-ray emission mechanisms of the radio jet and consider thermal emission from interaction between radio outflow and the NLR clouds the most probable origin for the X-ray emission associated with the jet.

Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection.

PubMed

Tummers, Willemieke S; Warram, Jason M; Tipirneni, Kiranya E; Fengler, John; Jacobs, Paula; Shankar, Lalitha; Henderson, Lori; Ballard, Betsy; Pogue, Brian W; Weichert, Jamey P; Bouvet, Michael; Sorger, Jonathan; Contag, Christopher H; Frangioni, John V; Tweedle, Michael F; Basilion, James P; Gambhir, Sanjiv S; Rosenthal, Eben L

2017-05-01

Considerable advances in cancer-specific optical imaging have improved the precision of tumor resection. In comparison to traditional imaging modalities, this technology is unique in its ability to provide real-time feedback to the operating surgeon. Given the significant clinical implications of optical imaging, there is an urgent need to standardize surgical navigation tools and contrast agents to facilitate swift regulatory approval. Because fluorescence-enhanced surgery requires a combination of both device and drug, each may be developed in conjunction, or separately, which are important considerations in the approval process. This report is the result of a one-day meeting held on May 4, 2016 with officials from the National Cancer Institute, the FDA, members of the American Society of Image-Guided Surgery, and members of the World Molecular Imaging Society, which discussed consensus methods for FDA-directed human testing and approval of investigational optical imaging devices as well as contrast agents for surgical applications. The goal of this workshop was to discuss FDA approval requirements and the expectations for approval of these novel drugs and devices, packaged separately or in combination, within the context of optical surgical navigation. In addition, the workshop acted to provide clarity to the research community on data collection and trial design. Reported here are the specific discussion items and recommendations from this critical and timely meeting. Cancer Res; 77(9); 2197-206. ©2017 AACR . ©2017 American Association for Cancer Research.

An inexpensive programmable illumination microscope with active feedback

PubMed Central

Tompkins, Nathan; Fraden, Seth

2016-01-01

We have developed a programmable illumination system capable of tracking and illuminating numerous objects simultaneously using only low-cost and reused optical components. The active feedback control software allows for a closed-loop system that tracks and perturbs objects of interest automatically. Our system uses a static stage where the objects of interest are tracked computationally as they move across the field of view allowing for a large number of simultaneous experiments. An algorithmically determined illumination pattern can be applied anywhere in the field of view with simultaneous imaging and perturbation using different colors of light to enable spatially and temporally structured illumination. Our system consists of a consumer projector, camera, 35-mm camera lens, and a small number of other optical and scaffolding components. The entire apparatus can be assembled for under $4,000. PMID:27642182

MQW Optical Feedback Modulators And Phase Shifters

NASA Technical Reports Server (NTRS)

Jackson, Deborah J.

1995-01-01

Laser diodes equipped with proposed multiple-quantum-well (MQW) optical feedback modulators prove useful in variety of analog and digital optical-communication applications, including fiber-optic signal-distribution networks and high-speed, low-crosstalk interconnections among super computers or very-high-speed integrated circuits. Development exploits accompanying electro-optical aspect of QCSE - variation in index of refraction with applied electric field. Also exploits sensitivity of laser diodes to optical feedback. Approach is reverse of prior approach.

Evaluation of microsurgical tasks with OCT-guided and/or robot-assisted ophthalmic forceps

PubMed Central

Yu, Haoran; Shen, Jin-Hui; Shah, Rohan J.; Simaan, Nabil; Joos, Karen M.

2015-01-01

Real-time intraocular optical coherence tomography (OCT) visualization of tissues with surgical feedback can enhance retinal surgery. An intraocular 23-gauge B-mode forward-imaging co-planar OCT-forceps, coupling connectors and algorithms were developed to form a unique ophthalmic surgical robotic system. Approach to the surface of a phantom or goat retina by a manual or robotic-controlled forceps, with and without real-time OCT guidance, was performed. Efficiency of lifting phantom membranes was examined. Placing the co-planar OCT imaging probe internal to the surgical tool reduced instrument shadowing and permitted constant tracking. Robotic assistance together with real-time OCT feedback improved depth perception accuracy. The first-generation integrated OCT-forceps was capable of peeling membrane phantoms despite smooth tips. PMID:25780736

Nonlinear adaptive optics: aberration correction in three photon fluorescence microscopy for mouse brain imaging

NASA Astrophysics Data System (ADS)

Sinefeld, David; Paudel, Hari P.; Wang, Tianyu; Wang, Mengran; Ouzounov, Dimitre G.; Bifano, Thomas G.; Xu, Chris

2017-02-01

Multiphoton fluorescence microscopy is a well-established technique for deep-tissue imaging with subcellular resolution. Three-photon microscopy (3PM) when combined with long wavelength excitation was shown to allow deeper imaging than two-photon microscopy (2PM) in biological tissues, such as mouse brain, because out-of-focus background light can be further reduced due to the higher order nonlinear excitation. As was demonstrated in 2PM systems, imaging depth and resolution can be improved by aberration correction using adaptive optics (AO) techniques which are based on shaping the scanning beam using a spatial light modulator (SLM). In this way, it is possible to compensate for tissue low order aberration and to some extent, to compensate for tissue scattering. Here, we present a 3PM AO microscopy system for brain imaging. Soliton self-frequency shift is used to create a femtosecond source at 1675 nm and a microelectromechanical (MEMS) SLM serves as the wavefront shaping device. We perturb the 1020 segment SLM using a modified nonlinear version of three-point phase shifting interferometry. The nonlinearity of the fluorescence signal used for feedback ensures that the signal is increasing when the spot size decreases, allowing compensation of phase errors in an iterative optimization process without direct phase measurement. We compare the performance for different orders of nonlinear feedback, showing an exponential growth in signal improvement as the nonlinear order increases. We demonstrate the impact of the method by applying the 3PM AO system for in-vivo mouse brain imaging, showing improvement in signal at 1-mm depth inside the brain.

Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system.

PubMed

Jang, Andrew T; Chan, Kenneth H; Fried, Daniel

2017-09-01

The purpose of this study is to assemble a laser system for the selective removal of dental composite from tooth surfaces, that is feasible for clinical use incorporating a spectral feedback system, a scanning system, articulating arm and a clinical hand-piece, and evaluate the performance of that system on extracted teeth. Ten extracted teeth were collected and small fillings were placed on the occlusal surface of each tooth. A clinical system featuring a CO 2 laser operating at 50 Hz and spectral optical feedback was used to remove the composite. Removal was confirmed using a cross polarized optical coherence tomography (CP-OCT) system designed for clinical use. The system was capable of rapidly removing composite from small preparations on tooth occlusal surfaces with a mean loss of enamel of less than 20 μm. We have demonstrated that spectral feedback can be successfully employed in an automated system for composite removal by incorporating dual photodiodes and a galvanometer controlled CO 2 laser. Additionally, the use of registered OCT images presents as a viable method for volumetric benchmarking. Overall, this study represents the first implementation of spectral feedback into a clinical hand-piece and serves as a benchmark for a future clinical study. Lasers Surg. Med. 49:658-665, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Control of Formation-Flying Multi-Element Space Interferometers with Direct Interferometer-Output Feedback

NASA Technical Reports Server (NTRS)

Lu, Hui-Ling; Cheng, H. L.; Lyon, Richard G.; Carpenter, Kenneth G.

2007-01-01

The long-baseline space interferometer concept involving formation flying of multiple spacecraft holds great promise as future space missions for high-resolution imagery. A major challenge of obtaining high-quality interferometric synthesized images from long-baseline space interferometers is to accurately control these spacecraft and their optics payloads in the specified configuration. Our research focuses on the determination of the optical errors to achieve fine control of long-baseline space interferometers without resorting to additional sensing equipment. We present a suite of estimation tools that can effectively extract from the raw interferometric image relative x/y, piston translational and tip/tilt deviations at the exit pupil aperture. The use of these error estimates in achieving control of the interferometer elements is demonstrated using simulated as well as laboratory-collected interferometric stellar images.

Control of Formation-Flying Multi-Element Space Interferometers with Direct Interferometer-Output Feedback

NASA Technical Reports Server (NTRS)

Lu, Hui-Ling; Cheng, Victor H. L.; Lyon, Richard G.; Carpenter, Kenneth G.

2007-01-01

The long-baseline space interferometer concept involving formation flying of multiple spacecrafts holds great promise as future space missions for high-resolution imagery. A major challenge of obtaining high-quality interferometric synthesized images from long-baseline space interferometers is to accurately control these spacecraft and their optics payloads in the specified configuration. Our research focuses on the determination of the optical errors to achieve fine control of long-baseline space interferometers without resorting to additional sensing equipment. We present a suite of estimation tools that can effectively extract from the raw interferometric image relative x/y, piston translational and tip/tilt deviations at the exit pupil aperture. The use of these error estimates in achieving control of the interferometer elements is demonstrated using simulated as well as laboratory-collected interferometric stellar images.

Photonic-powered cable assembly

DOEpatents

Sanderson, Stephen N.; Appel, Titus James; Wrye, IV, Walter C.

2013-01-22

A photonic-cable assembly includes a power source cable connector ("PSCC") coupled to a power receive cable connector ("PRCC") via a fiber cable. The PSCC electrically connects to a first electronic device and houses a photonic power source and an optical data transmitter. The fiber cable includes an optical transmit data path coupled to the optical data transmitter, an optical power path coupled to the photonic power source, and an optical feedback path coupled to provide feedback control to the photonic power source. The PRCC electrically connects to a second electronic device and houses an optical data receiver coupled to the optical transmit data path, a feedback controller coupled to the optical feedback path to control the photonic power source, and a photonic power converter coupled to the optical power path to convert photonic energy received over the optical power path to electrical energy to power components of the PRCC.

Photonic-powered cable assembly

DOEpatents

Sanderson, Stephen N; Appel, Titus James; Wrye, IV, Walter C

2014-06-24

A photonic-cable assembly includes a power source cable connector ("PSCC") coupled to a power receive cable connector ("PRCC") via a fiber cable. The PSCC electrically connects to a first electronic device and houses a photonic power source and an optical data transmitter. The fiber cable includes an optical transmit data path coupled to the optical data transmitter, an optical power path coupled to the photonic power source, and an optical feedback path coupled to provide feedback control to the photonic power source. The PRCC electrically connects to a second electronic device and houses an optical data receiver coupled to the optical transmit data path, a feedback controller coupled to the optical feedback path to control the photonic power source, and a photonic power converter coupled to the optical power path to convert photonic energy received over the optical power path to electrical energy to power components of the PRCC.

Regimes of external optical feedback in 5.6 μm distributed feedback mid-infrared quantum cascade lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jumpertz, L., E-mail: louise.jumpertz@telecom-paristech.fr; Alcatel Thales III-V Lab, Campus de Polytechnique, 1 avenue Augustin Fresnel, 91767 Palaiseau; Carras, M.

2014-09-29

External optical feedback is studied experimentally in mid-infrared quantum cascade lasers. These structures exhibit a dynamical response close to that observed in interband lasers, with threshold reduction and optical power enhancement when increasing the feedback ratio. The study of the optical spectrum proves that the laser undergoes five distinct regimes depending on the phase and amplitude of the reinjected field. These regimes are mapped in the plane of external cavity length and feedback strength, revealing unstable behavior only for a very narrow range of operation, making quantum cascade lasers much more stable than their interband counterparts.

Holographic Associative Memory Employing Phase Conjugation

NASA Astrophysics Data System (ADS)

Soffer, B. H.; Marom, E.; Owechko, Y.; Dunning, G.

1986-12-01

The principle of information retrieval by association has been suggested as a basis for parallel computing and as the process by which human memory functions.1 Various associative processors have been proposed that use electronic or optical means. Optical schemes,2-7 in particular, those based on holographic principles,8'8' are well suited to associative processing because of their high parallelism and information throughput. Previous workers8 demonstrated that holographically stored images can be recalled by using relatively complicated reference images but did not utilize nonlinear feedback to reduce the large cross talk that results when multiple objects are stored and a partial or distorted input is used for retrieval. These earlier approaches were limited in their ability to reconstruct the output object faithfully from a partial input.

Optical diagnostics in gas turbine combustors

NASA Astrophysics Data System (ADS)

Woodruff, Steven D.

1999-01-01

Deregulation of the power industry and increasingly tight emission controls are pushing gas turbine manufacturers to develop engines operating at high pressure for efficiency and lean fuel mixtures to control NOx. This combination also gives rise to combustion instabilities which threaten engine integrity through acoustic pressure oscillations and flashback. High speed imaging and OH emission sensors have been demonstrated to be invaluable tools in characterizing and monitoring unstable combustion processes. Asynchronous imaging technique permit detailed viewing of cyclic flame structure in an acoustic environment which may be modeled or utilized in burner design . The response of the flame front to the acoustic pressure cycle may be tracked with an OH emission monitor using a sapphire light pipe for optical access. The OH optical emission can be correlated to pressure sensor data for better understanding of the acoustical coupling of the flame. Active control f the combustion cycle can be implemented using an OH emission sensor for feedback.

Optoelectronic tweezers for microparticle and cell manipulation

NASA Technical Reports Server (NTRS)

Wu, Ming Chiang (Inventor); Chiou, Pei Yu (Inventor); Ohta, Aaron T. (Inventor)

2009-01-01

An optical image-driven light induced dielectrophoresis (DEP) apparatus and method are described which provide for the manipulation of particles or cells with a diameter on the order of 100 .mu.m or less. The apparatus is referred to as optoelectric tweezers (OET) and provides a number of advantages over conventional optical tweezers, in particular the ability to perform operations in parallel and over a large area without damage to living cells. The OET device generally comprises a planar liquid-filled structure having one or more portions which are photoconductive to convert incoming light to a change in the electric field pattern. The light patterns are dynamically generated to provide a number of manipulation structures that can manipulate single particles and cells or groups of particles/cells. The OET preferably includes a microscopic imaging means to provide feedback for the optical manipulation, such as detecting position and characteristics wherein the light patterns are modulated accordingly.

Optoelectronic Tweezers for Microparticle and Cell Manipulation

NASA Technical Reports Server (NTRS)

Wu, Ming Chiang (Inventor); Chiou, Pei-Yu (Inventor); Ohta, Aaron T. (Inventor)

2014-01-01

An optical image-driven light induced dielectrophoresis (DEP) apparatus and method are described which provide for the manipulation of particles or cells with a diameter on the order of 100 micromillimeters or less. The apparatus is referred to as optoelectric tweezers (OET) and provides a number of advantages over conventional optical tweezers, in particular the ability to perform operations in parallel and over a large area without damage to living cells. The OET device generally comprises a planar liquid-filled structure having one or more portions which are photoconductive to convert incoming light to a change in the electric field pattern. The light patterns are dynamically generated to provide a number of manipulation structures that can manipulate single particles and cells or group of particles/cells. The OET preferably includes a microscopic imaging means to provide feedback for the optical manipulation, such as detecting position and characteristics wherein the light patterns are modulated accordingly.

Combination of optical shape measurement and augmented reality for task support: II. Real-time feedback of shape measurement results

NASA Astrophysics Data System (ADS)

Yamauchi, Makoto; Iwamoto, Kazuyo

2010-05-01

Line heating is a skilled task in shipbuilding to shape the outer plates of ship hulls. Real-time information on the deformation of the plates during the task would be helpful to workers performing this process. Therefore, we herein propose an interactive scheme for supporting workers performing line heating; the system provides such information through an optical shape measurement instrument combined with an augmented reality (AR) system. The instrument was designed and fabricated so that the measured data were represented using coordinates based on fiducial markers. Since the markers were simultaneously used in the AR system for the purpose of positioning, the data could then be displayed to the workers through a head-mounted display as a virtual image overlaid on the plates. Feedback of the shape measurement results was thus performed in real time using the proposed system.

Real-time optical signal processors employing optical feedback: amplitude and phase control.

PubMed

Gallagher, N C

1976-04-01

The development of real-time coherent optical signal processors has increased the appeal of optical computing techniques in signal processing applications. A major limitation of these real-time systems is the. fact that the optical processing material is generally of a phase-only type. The result is that the spatial filters synthesized with these systems must be either phase-only filters or amplitude-only filters. The main concern of this paper is the application of optical feedback techniques to obtain simultaneous and independent amplitude and phase control of the light passing through the system. It is shown that optical feedback techniques may be employed with phase-only spatial filters to obtain this amplitude and phase control. The feedback system with phase-only filters is compared with other feedback systems that employ combinations of phase-only and amplitude-only filters; it is found that the phase-only system is substantially more flexible than the other two systems investigated.

Intra-opeartive OCT imaging and sensing devices for clinical translation (Conference Presentation)

NASA Astrophysics Data System (ADS)

Chen, Yu

2017-02-01

Stereotactic procedures that require insertion of needle-based instruments into the brain serve important roles in a variety of neurosurgical interventions, such as biopsy, catheterization, and electrode placement. A fundamental limitation of these stereotactic procedures is that they are blind procedures in that the operator does not have real-time feedback as to what lies immediately ahead of the advancing needle. Therefore, there is a great clinical need to navigate the instrument safely and accurately to the targets. Towards that end, we developed a forwarding-imaging needle-type optical coherence tomography (OCT) probe for avoiding the hemorrhage and guiding neurosurgical interventions. The needle probe has a thin diameter of 0.7 mm. The feasibility of vessel detection and neurosurgical guidance were demonstrated on sheep brain in vivo and human brain ex vivo. In addition, we further reduced the probe size to 0.3 mm using an optical Doppler sensing (ODS) fiber probe that can integrate with microelectrode recording (MER) to detect the blood vessels lying ahead to improve the safety of this procedure. Furthermore, to overcome the field-of-view limitation of OCT probe, we developed an MRI-compatible OCT imaging probe for neurosurgery. MRI/OCT multi-scale imaging integrates micro-resolution optical imaging with wide-field MRI imaging, and has potential to further improve the targeting accuracy.

Optical feedback effects on terahertz quantum cascade lasers: modelling and applications

NASA Astrophysics Data System (ADS)

Rakić, Aleksandar D.; Lim, Yah Leng; Taimre, Thomas; Agnew, Gary; Qi, Xiaoqiong; Bertling, Karl; Han, She; Wilson, Stephen J.; Kundu, Iman; Grier, Andrew; Ikonić, Zoran; Valavanis, Alexander; Demić, Aleksandar; Keeley, James; Li, Lianhe H.; Linfield, Edmund H.; Davies, A. Giles; Harrison, Paul; Ferguson, Blake; Walker, Graeme; Prow, Tarl; Indjin, Dragan; Soyer, H. Peter

2016-11-01

Terahertz (THz) quantum cascade lasers (QCLs) are compact sources of radiation in the 1-5 THz range with significant potential for applications in sensing and imaging. Laser feedback interferometry (LFI) with THz QCLs is a technique utilizing the sensitivity of the QCL to the radiation reflected back into the laser cavity from an external target. We will discuss modelling techniques and explore the applications of LFI in biological tissue imaging and will show that the confocal nature of the QCL in LFI systems, with their innate capacity for depth sectioning, makes them suitable for skin diagnostics with the well-known advantages of more conventional confocal microscopes. A demonstration of discrimination of neoplasia from healthy tissue using a THz, LFI-based system in the context of melanoma is presented using a transgenic mouse model.

Shaping Microwave Fields Using Nonlinear Unsolicited Feedback: Application to Enhance Energy Harvesting

NASA Astrophysics Data System (ADS)

del Hougne, Philipp; Fink, Mathias; Lerosey, Geoffroy

2017-12-01

Wave-front shaping has emerged over the past decade as a powerful tool to control wave propagation through complex media, initially in optics and more recently also in the microwave domain with important applications in telecommunication, imaging, and energy transfer. The crux of implementing wave-front shaping concepts in real life is often its need for (direct) feedback, requiring access to the target to focus on. Here, we present the shaping of a microwave field based on indirect, unsolicited, and blind feedback which may be the pivotal step towards practical implementations. With the example of a radio-frequency harvester in a metallic cavity, we demonstrate tenfold enhancement of the harvested power by wave-front shaping based on nonlinear signals detected at an arbitrary position away from the harvesting device.

Clinical development of BLZ-100 for real-time optical imaging of tumors during resection

NASA Astrophysics Data System (ADS)

Franklin, Heather L.; Miller, Dennis M.; Hedges, Teresa; Perry, Jeff; Parrish-Novak, Julia

2016-03-01

Complete initial resection can give cancer patients the best opportunity for long-term survival. There is unmet need in surgical oncology for optical imaging that enables simple and precise visualization of tumors and consistent contrast with surrounding normal tissues. Near-infrared (NIR) contrast agents and camera systems that can detect them represent an area of active research and development. The investigational Tumor Paint agent BLZ-100 is a conjugate of a chlorotoxin peptide and the NIR dye indocyanine green (ICG) that has been shown to specifically bind to a broad range of solid tumors. Clinical efficacy studies with BLZ-100 are in progress, a necessary step in bringing the product into clinical practice. To ensure a product that will be useful for and accepted by surgeons, the early clinical development of BLZ- 100 incorporates multiple tumor types and imaging devices so that surgeon feedback covers the range of anticipated clinical uses. Key contrast agent characteristics include safety, specificity, flexibility in timing between dose and surgery, and breadth of tumor types recognized. Imaging devices should use wavelengths that are optimal for the contrast agent, be sensitive enough that contrast agent dosing can be adjusted for optimal contrast, include real-time video display of fluorescence and white light image, and be simple for surgeons to use with minimal disruption of surgical flow. Rapid entry into clinical studies provides the best opportunity for early surgeon feedback, enabling development of agents and devices that will gain broad acceptance and provide information that helps surgeons achieve more complete and precise resections.

Theoretical modeling of the dynamics of a semiconductor laser subject to double-reflector optical feedback

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bakry, A.; Abdulrhmann, S.; Ahmed, M., E-mail: mostafa.farghal@mu.edu.eg

2016-06-15

We theoretically model the dynamics of semiconductor lasers subject to the double-reflector feedback. The proposed model is a new modification of the time-delay rate equations of semiconductor lasers under the optical feedback to account for this type of the double-reflector feedback. We examine the influence of adding the second reflector to dynamical states induced by the single-reflector feedback: periodic oscillations, period doubling, and chaos. Regimes of both short and long external cavities are considered. The present analyses are done using the bifurcation diagram, temporal trajectory, phase portrait, and fast Fourier transform of the laser intensity. We show that adding themore » second reflector attracts the periodic and perioddoubling oscillations, and chaos induced by the first reflector to a route-to-continuous-wave operation. During this operation, the periodic-oscillation frequency increases with strengthening the optical feedback. We show that the chaos induced by the double-reflector feedback is more irregular than that induced by the single-reflector feedback. The power spectrum of this chaos state does not reflect information on the geometry of the optical system, which then has potential for use in chaotic (secure) optical data encryption.« less

Hybrid overlay metrology for high order correction by using CDSEM

NASA Astrophysics Data System (ADS)

Leray, Philippe; Halder, Sandip; Lorusso, Gian; Baudemprez, Bart; Inoue, Osamu; Okagawa, Yutaka

2016-03-01

Overlay control has become one of the most critical issues for semiconductor manufacturing. Advanced lithographic scanners use high-order corrections or correction per exposure to reduce the residual overlay. It is not enough in traditional feedback of overlay measurement by using ADI wafer because overlay error depends on other process (etching process and film stress, etc.). It needs high accuracy overlay measurement by using AEI wafer. WIS (Wafer Induced Shift) is the main issue for optical overlay, IBO (Image Based Overlay) and DBO (Diffraction Based Overlay). We design dedicated SEM overlay targets for dual damascene process of N10 by i-ArF multi-patterning. The pattern is same as device-pattern locally. Optical overlay tools select segmented pattern to reduce the WIS. However segmentation has limit, especially the via-pattern, for keeping the sensitivity and accuracy. We evaluate difference between the viapattern and relaxed pitch gratings which are similar to optical overlay target at AEI. CDSEM can estimate asymmetry property of target from image of pattern edge. CDSEM can estimate asymmetry property of target from image of pattern edge. We will compare full map of SEM overlay to full map of optical overlay for high order correction ( correctables and residual fingerprints).

Interactive brain shift compensation using GPU based programming

NASA Astrophysics Data System (ADS)

van der Steen, Sander; Noordmans, Herke Jan; Verdaasdonk, Rudolf

2009-02-01

Processing large images files or real-time video streams requires intense computational power. Driven by the gaming industry, the processing power of graphic process units (GPUs) has increased significantly. With the pixel shader model 4.0 the GPU can be used for image processing 10x faster than the CPU. Dedicated software was developed to deform 3D MR and CT image sets for real-time brain shift correction during navigated neurosurgery using landmarks or cortical surface traces defined by the navigation pointer. Feedback was given using orthogonal slices and an interactively raytraced 3D brain image. GPU based programming enables real-time processing of high definition image datasets and various applications can be developed in medicine, optics and image sciences.

Fabrication and characterization of a nanometer-sized optical fiber electrode based on selective chemical etching for scanning electrochemical/optical microscopy.

PubMed

Maruyama, Kenichi; Ohkawa, Hiroyuki; Ogawa, Sho; Ueda, Akio; Niwa, Osamu; Suzuki, Koji

2006-03-15

We have already reported a method for fabricating ultramicroelectrodes (Suzuki, K. JP Patent, 2004-45394, 2004). This method is based on the selective chemical etching of optical fibers. In this work, we undertake a detailed investigation involving a combination of etched optical fibers with various types of tapered tip (protruding-shape, double- (or pencil-) shape and triple-tapered electrode) and insulation with electrophoretic paint. Our goal is to establish a method for fabricating nanometer-sized optical fiber electrodes with high reproducibility. As a result, we realized pencil-shaped and triple-tapered electrodes that had radii in the nanometer range with high reproducibility. These nanometer-sized electrodes showed well-defined sigmoidal curves and stable diffusion-limited responses with cyclic voltammetry. The pencil-shaped optical fiber, which has a conical tip with a cone angle of 20 degrees , was effective for controlling the electrode radius. The pencil-shaped electrodes had higher reproducibility and smaller electrode radii (r(app) < 1.0 nm) than those of other etched optical fiber electrodes. By using a pencil-shaped electrode with a 105-nm radius as a probe, we obtained simultaneous electrochemical and optical images of an implantable interdigitated array electrode. We achieved nanometer-scale resolution with a combination of scanning electrochemical microscopy SECM and optical microscopy. The resolution of the electrochemical and optical images indicated sizes of 300 and 930 nm, respectively. The neurites of living PC12 cells were also successfully imaged on a 1.6-microm scale by using the negative feedback mode of an SECM.

Prediction performance of reservoir computing systems based on a diode-pumped erbium-doped microchip laser subject to optical feedback.

PubMed

Nguimdo, Romain Modeste; Lacot, Eric; Jacquin, Olivier; Hugon, Olivier; Van der Sande, Guy; Guillet de Chatellus, Hugues

2017-02-01

Reservoir computing (RC) systems are computational tools for information processing that can be fully implemented in optics. Here, we experimentally and numerically show that an optically pumped laser subject to optical delayed feedback can yield similar results to those obtained for electrically pumped lasers. Unlike with previous implementations, the input data are injected at a time interval that is much larger than the time-delay feedback. These data are directly coupled to the feedback light beam. Our results illustrate possible new avenues for RC implementations for prediction tasks.

Advances in single-cell experimental design made possible by automated imaging platforms with feedback through segmentation.

PubMed

Crick, Alex J; Cammarota, Eugenia; Moulang, Katie; Kotar, Jurij; Cicuta, Pietro

2015-01-01

Live optical microscopy has become an essential tool for studying the dynamical behaviors and variability of single cells, and cell-cell interactions. However, experiments and data analysis in this area are often extremely labor intensive, and it has often not been achievable or practical to perform properly standardized experiments on a statistically viable scale. We have addressed this challenge by developing automated live imaging platforms, to help standardize experiments, increasing throughput, and unlocking previously impossible ones. Our real-time cell tracking programs communicate in feedback with microscope and camera control software, and they are highly customizable, flexible, and efficient. As examples of our current research which utilize these automated platforms, we describe two quite different applications: egress-invasion interactions of malaria parasites and red blood cells, and imaging of immune cells which possess high motility and internal dynamics. The automated imaging platforms are able to track a large number of motile cells simultaneously, over hours or even days at a time, greatly increasing data throughput and opening up new experimental possibilities. Copyright © 2015 Elsevier Inc. All rights reserved.

Selective Removal of Natural Occlusal Caries by Coupling Near-infrared Imaging with a CO2 Laser

PubMed Central

Tao, You-Chen; Fried, Daniel

2011-01-01

Laser removal of dental hard tissue can be combined with optical, spectral or acoustic feedback systems to selectively ablate dental caries and restorative materials. Near-infrared (NIR) imaging has considerable potential for the optical discrimination of sound and demineralized tissue. Last year we successfully demonstrated that near-IR images can be used to guide a CO2 laser ablation system for the selective removal of artificial caries lesions on smooth surfaces. The objective of this study was to test the hypothesis that two-dimensional near-infrared images of natural occlusal caries can be used to guide a CO2 laser for selective removal. Two-dimensional NIR images were acquired at 1310-nm of extracted human molar teeth with occlusal caries. Polarization sensitive optical coherence tomography (PS-OCT) was also used to acquire depth-resolved images of the lesion areas. An imaging processing module was developed to analyze the NIR imaging output and generate optical maps that were used to guide a CO2 laser to selectively remove the lesions at a uniform depth. Post-ablation NIR images were acquired to verify caries removal. Based on the analysis of the NIR images, caries lesions were selectively removed with a CO2 laser while sound tissues were conserved. However, the removal rate varied markedly with the severity of decay and multiple passes were required for caries removal. These initial results are promising but indicate that the selective removal of natural caries is more challenging than the selective removal of artificial lesions due to varying tooth geometry, the highly variable organic/mineral ratio in natural lesions and more complicated lesion structure. PMID:21909225

Selective removal of natural occlusal caries by coupling near-infrared imaging with a CO II laser

NASA Astrophysics Data System (ADS)

Tao, You-Chen; Fried, Daniel

2008-02-01

Laser removal of dental hard tissue can be combined with optical, spectral or acoustic feedback systems to selectively ablate dental caries and restorative materials. Near-infrared (NIR) imaging has considerable potential for the optical discrimination of sound and demineralized tissue. Last year we successfully demonstrated that near-IR images can be used to guide a CO2 laser ablation system for the selective removal of artificial caries lesions on smooth surfaces. The objective of this study was to test the hypothesis that two-dimensional near-infrared images of natural occlusal caries can be used to guide a CO2 laser for selective removal. Two-dimensional NIR images were acquired at 1310-nm of extracted human molar teeth with occlusal caries. Polarization sensitive optical coherence tomography (PS-OCT) was also used to acquire depth-resolved images of the lesion areas. An imaging processing module was developed to analyze the NIR imaging output and generate optical maps that were used to guide a CO2 laser to selectively remove the lesions at a uniform depth. Post-ablation NIR images were acquired to verify caries removal. Based on the analysis of the NIR images, caries lesions were selectively removed with a CO2 laser while sound tissues were conserved. However, the removal rate varied markedly with the severity of decay and multiple passes were required for caries removal. These initial results are promising but indicate that the selective removal of natural caries is more challenging than the selective removal of artificial lesions due to varying tooth geometry, the highly variable organic/mineral ratio in natural lesions and more complicated lesion structure.

Selective Removal of Natural Occlusal Caries by Coupling Near-infrared Imaging with a CO(2) Laser.

PubMed

Tao, You-Chen; Fried, Daniel

2008-03-01

Laser removal of dental hard tissue can be combined with optical, spectral or acoustic feedback systems to selectively ablate dental caries and restorative materials. Near-infrared (NIR) imaging has considerable potential for the optical discrimination of sound and demineralized tissue. Last year we successfully demonstrated that near-IR images can be used to guide a CO(2) laser ablation system for the selective removal of artificial caries lesions on smooth surfaces. The objective of this study was to test the hypothesis that two-dimensional near-infrared images of natural occlusal caries can be used to guide a CO(2) laser for selective removal. Two-dimensional NIR images were acquired at 1310-nm of extracted human molar teeth with occlusal caries. Polarization sensitive optical coherence tomography (PS-OCT) was also used to acquire depth-resolved images of the lesion areas. An imaging processing module was developed to analyze the NIR imaging output and generate optical maps that were used to guide a CO(2) laser to selectively remove the lesions at a uniform depth. Post-ablation NIR images were acquired to verify caries removal. Based on the analysis of the NIR images, caries lesions were selectively removed with a CO(2) laser while sound tissues were conserved. However, the removal rate varied markedly with the severity of decay and multiple passes were required for caries removal. These initial results are promising but indicate that the selective removal of natural caries is more challenging than the selective removal of artificial lesions due to varying tooth geometry, the highly variable organic/mineral ratio in natural lesions and more complicated lesion structure.

Passive method of eliminating accommodation/convergence disparity in stereoscopic head-mounted displays

NASA Astrophysics Data System (ADS)

Eichenlaub, Jesse B.

2005-03-01

The difference in accommodation and convergence distance experienced when viewing stereoscopic displays has long been recognized as a source of visual discomfort. It is especially problematic in head mounted virtual reality and enhanced reality displays, where images must often be displayed across a large depth range or superimposed on real objects. DTI has demonstrated a novel method of creating stereoscopic images in which the focus and fixation distances are closely matched for all parts of the scene from close distances to infinity. The method is passive in the sense that it does not rely on eye tracking, moving parts, variable focus optics, vibrating optics, or feedback loops. The method uses a rapidly changing illumination pattern in combination with a high speed microdisplay to create cones of light that converge at different distances to form the voxels of a high resolution space filling image. A bench model display was built and a series of visual tests were performed in order to demonstrate the concept and investigate both its capabilities and limitations. Results proved conclusively that real optical images were being formed and that observers had to change their focus to read text or see objects at different distances

Associative Memory In A Phase Conjugate Resonator Cavity Utilizing A Hologram

NASA Astrophysics Data System (ADS)

Owechko, Y.; Marom, E.; Soffer, B. H.; Dunning, G.

1987-01-01

The principle of information retrieval by association has been suggested as a basis for parallel computing and as the process by which human memory functions.1 Various associative processors have been proposed that use electronic or optical means. Optical schemes,2-7 in particular, those based on holographic principles,3,6,7 are well suited to associative processing because of their high parallelism and information throughput. Previous workers8 demonstrated that holographically stored images can be recalled by using relatively complicated reference images but did not utilize nonlinear feedback to reduce the large cross talk that results when multiple objects are stored and a partial or distorted input is used for retrieval. These earlier approaches were limited in their ability to reconstruct the output object faithfully from a partial input.

THz QCL self-mixing interferometry for biomedical applications

NASA Astrophysics Data System (ADS)

Rakić, Aleksandar D.; Taimre, Thomas; Bertling, Karl; Lim, Yah Leng; Wilson, Stephen J.; Nikolić, Milan; Valavanis, Alexander; Indjin, Dragan; Linfield, Edmund H.; Davies, A. Giles; Ferguson, Blake; Walker, Graeme; Schaider, Helmut; Soyer, H. Peter

2014-09-01

In this paper, we introduce the self-mixing phenomenon in terahertz quantum cascade lasers (THz QCLs) and present recent advancements in the development of coherent THz imaging and sensing systems that exploit the self-mixing effect. We describe an imaging method which utilises the interferometric nature of optical feedback in a THz QCL to employ it as a homodyning transceiver. This results in a highly sensitive and compact scheme. Due to the inherently low penetration depth of THz radiation in hydrated biological tissue, imaging of superficial skin is an ideal application for this technique. We present results for imaging of excised skin tissue, showing high-contrast between different tissue types and pathologies.

Advanced Optical Diagnostic Methods for Describing Fuel Injection and Combustion Flowfield Phenomena

NASA Technical Reports Server (NTRS)

Locke, Randy J.; Hicks, Yolanda R.; Anderson, Robert C.

2004-01-01

Over the past decade advanced optical diagnostic techniques have evolved and matured to a point where they are now widely applied in the interrogation of high pressure combusting flows. At NASA Glenn Research Center (GRC), imaging techniques have been used successfully in on-going work to develop the next generation of commercial aircraft gas turbine combustors. This work has centered on providing a means by which researchers and designers can obtain direct visual observation and measurements of the fuel injection/mixing/combustion processes and combustor flowfield in two- and three-dimensional views at actual operational conditions. Obtaining a thorough understanding of the chemical and physical processes at the extreme operating conditions of the next generation of combustors is critical to reducing emissions and increasing fuel efficiency. To accomplish this and other tasks, the diagnostic team at GRC has designed and constructed optically accessible, high pressurer high temperature flame tubes and sectar rigs capable of optically probing the 20-60 atm flowfields of these aero-combustors. Among the techniques employed at GRC are planar laser-induced fluorescence (PLIF) for imaging molecular species as well as liquid and gaseous fuel; planar light scattering (PLS) for imaging fuel sprays and droplets; and spontaneous Raman scattering for species and temperature measurement. Using these techniques, optical measurements never before possible have been made in the actual environments of liquid fueled gas turbines. 2-D mapping of such parameters as species (e.g. OH-, NO and kerosene-based jet fuel) distribution, injector spray angle, and fuel/air distribution are just some of the measurements that are now routinely made. Optical imaging has also provided prompt feedback to researchers regarding the effects of changes in the fuel injector configuration on both combustor performance and flowfield character. Several injector design modifications and improvements have resulted from this feedback. Alternate diagnostic methods are constantly being evaluated as to their suitability as a diagnostic tool in these environments. A new method currently under examination is background oriented Schlieren (BOS) for examining the fuel/air mixing processes. While ratioing the Stokes and anti-Stokes nitrogen lines obtained from spontaneous Raman is being refined for temperature measurement. While the primary focus of the GRC diagnostic work remains optical species measurement and flow stream characterization, an increased emphasis has been placed on our involvement in flame code validation efforts. A functional combustor code should shorten and streamline future combustor design. Quantitative measurements of flow parameters such as temperature, species concentration, drop size and velocity using such methods as Raman and phase Doppler anemometry will provide data necessary in this effort.

Optical-Path-Difference Linear Mechanism for the Panchromatic Fourier Transform Spectrometer

NASA Technical Reports Server (NTRS)

Blavier, Jean-Francois L.; Heverly, Matthew C.; Key, Richard W.; Sander, Stanley P.

2011-01-01

A document discusses a mechanism that uses flex-pivots in a parallelogram arrangement to provide frictionless motion with an unlimited lifetime. A voicecoil actuator drives the parallelogram over the required 5-cm travel. An optical position sensor provides feedback for a servo loop that keeps the velocity within 1 percent of expected value. Residual tip/tilt error is compensated for by a piezo actuator that drives the interferometer mirror. This mechanism builds on previous work that targeted ground-based measurements. The main novelty aspects include cryogenic and vacuum operation, high reliability for spaceflight, compactness of the design, optical layout compatible with the needs of an imaging FTS (i.e. wide overall field-of-view), and mirror optical coatings to cover very broad wavelength range (i.e., 0.26 to 15 m).

Comparison of control and quality of bone cutting by using optical topographical imaging guided mechanical drill and 1070 nm laser with in-line coherent imaging

NASA Astrophysics Data System (ADS)

Razani, Marjan; Soudagar, Yasaman; Yu, Karen; Galbraith, Christopher M.; Webster, Paul J. L.; Van Vlack, Cole; Sun, Cuiru; Mariampillai, Adrian; Leung, Michael K. K.; Standish, Beau; Kiehl, Tim-Rasmus; Fraser, James M.; Yang, Victor X. D.

2013-03-01

Precision depth control of bone resection is necessary for safe surgical procedures in the spine. In this paper, we compare the control and quality of cutting bovine tail bone, as an ex vivo model of laminectomy and bony resection simulating spinal surgery, planned with micro-CT data and executed using two approaches: (a) mechanical milling guided by optical topographical imaging (OTI) and (b) optical milling using closed-loop inline coherent imaging (ICI) to monitor and control the incision depth of a high-power 1070 nm fiber laser in situ. OTI provides the in situ topology of the 2-dimensional surface of the bone orientation in the mechanical mill which is registered with the treatment plan derived from the micro-CT data. The coregistration allows the plan to be programmed into the mill which is then used as a benchmark of current surgical techniques. For laser cutting, 3D optical land marking with coaxial camera vision and the ICI system is used to coregister the treatment plan. The unstable, carbonization-mediated ablation behaviour of 1070 nm light and the unknown initial geometry of bone leads to unpredictable ablation which substantially limits the depth accuracy of open-loop cutting. However, even with such a non-ideal cutting laser, we demonstrate that ICI provides in situ high-speed feedback that automatically and accurately limits the laser's cut depth to effectively create an all-optical analogue to the mechanical mill.

Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy

PubMed Central

Ughi, Giovanni J.; Gora, Michalina J.; Swager, Anne-Fré; Soomro, Amna; Grant, Catriona; Tiernan, Aubrey; Rosenberg, Mireille; Sauk, Jenny S.; Nishioka, Norman S.; Tearney, Guillermo J.

2016-01-01

Optical coherence tomography (OCT) is an optical diagnostic modality that can acquire cross-sectional images of the microscopic structure of the esophagus, including Barrett’s esophagus (BE) and associated dysplasia. We developed a swallowable tethered capsule OCT endomicroscopy (TCE) device that acquires high-resolution images of entire gastrointestinal (GI) tract luminal organs. This device has a potential to become a screening method that identifies patients with an abnormal esophagus that should be further referred for upper endoscopy. Currently, the characterization of the OCT-TCE esophageal wall data set is performed manually, which is time-consuming and inefficient. Additionally, since the capsule optics optimally focus light approximately 500 µm outside the capsule wall and the best quality images are obtained when the tissue is in full contact with the capsule, it is crucial to provide feedback for the operator about tissue contact during the imaging procedure. In this study, we developed a fully automated algorithm for the segmentation of in vivo OCT-TCE data sets and characterization of the esophageal wall. The algorithm provides a two-dimensional representation of both the contact map from the data collected in human clinical studies as well as a tissue map depicting areas of BE with or without dysplasia. Results suggest that these techniques can potentially improve the current TCE data acquisition procedure and provide an efficient characterization of the diseased esophageal wall. PMID:26977350

Fiber Optic Force Sensors for MRI-Guided Interventions and Rehabilitation: A Review

PubMed Central

Iordachita, Iulian I.; Tokuda, Junichi; Hata, Nobuhiko; Liu, Xuan; Seifabadi, Reza; Xu, Sheng; Wood, Bradford; Fischer, Gregory S.

2017-01-01

Magnetic Resonance Imaging (MRI) provides both anatomical imaging with excellent soft tissue contrast and functional MRI imaging (fMRI) of physiological parameters. The last two decades have witnessed the manifestation of increased interest in MRI-guided minimally invasive intervention procedures and fMRI for rehabilitation and neuroscience research. Accompanying the aspiration to utilize MRI to provide imaging feedback during interventions and brain activity for neuroscience study, there is an accumulated effort to utilize force sensors compatible with the MRI environment to meet the growing demand of these procedures, with the goal of enhanced interventional safety and accuracy, improved efficacy and rehabilitation outcome. This paper summarizes the fundamental principles, the state of the art development and challenges of fiber optic force sensors for MRI-guided interventions and rehabilitation. It provides an overview of MRI-compatible fiber optic force sensors based on different sensing principles, including light intensity modulation, wavelength modulation, and phase modulation. Extensive design prototypes are reviewed to illustrate the detailed implementation of these principles. Advantages and disadvantages of the sensor designs are compared and analyzed. A perspective on the future development of fiber optic sensors is also presented which may have additional broad clinical applications. Future surgical interventions or rehabilitation will rely on intelligent force sensors to provide situational awareness to augment or complement human perception in these procedures. PMID:28652857

A large-scan-angle piezoelectric MEMS optical scanner actuated by a Nb-doped PZT thin film

NASA Astrophysics Data System (ADS)

Naono, Takayuki; Fujii, Takamichi; Esashi, Masayoshi; Tanaka, Shuji

2014-01-01

Resonant 1D microelectromechanical systems (MEMS) optical scanners actuated by piezoelectric unimorph actuators with a Nb-doped lead zirconate titanate (PNZT) thin film were developed for endoscopic optical coherence tomography (OCT) application. The MEMS scanners were designed as the resonance frequency was less than 125 Hz to obtain enough pixels per frame in OCT images. The device size was within 3.4 mm × 2.5 mm, which is compact enough to be installed in a side-imaging probe with 4 mm inner diameter. The fabrication process started with a silicon-on-insulator wafer, followed by PNZT deposition by the Rf sputtering and Si bulk micromachining process. The fabricated MEMS scanners showed maximum optical scan angles of 146° at 90 Hz, 148° at 124 Hz, 162° at 180 Hz, and 152° at 394 Hz at resonance in atmospheric pressure. Such wide scan angles were obtained by a drive voltage below 1.3 Vpp, ensuring intrinsic safety in in vivo uses. The scanner with the unpoled PNZT film showed three times as large a scan angle as that with a poled PZT films. A swept-source OCT system was constructed using the fabricated MEMS scanner, and cross-sectional images of a fingertip with image widths of 4.6 and 2.3 mm were acquired. In addition, a PNZT-based angle sensor was studied for feedback operation.

Squeezed light in an optical parametric oscillator network with coherent feedback quantum control.

PubMed

Crisafulli, Orion; Tezak, Nikolas; Soh, Daniel B S; Armen, Michael A; Mabuchi, Hideo

2013-07-29

We present squeezing and anti-squeezing spectra of the output from a degenerate optical parametric oscillator (OPO) network arranged in different coherent quantum feedback configurations. One OPO serves as a quantum plant, the other as a quantum controller. The addition of coherent feedback enables shaping of the output squeezing spectrum of the plant, and is found to be capable of pushing the frequency of maximum squeezing away from the optical driving frequency and broadening the spectrum over a wider frequency band. The experimental results are in excellent agreement with the developed theory, and illustrate the use of coherent quantum feedback to engineer the quantum-optical properties of the plant OPO output.

Model for a pulsed terahertz quantum cascade laser under optical feedback.

PubMed

Agnew, Gary; Grier, Andrew; Taimre, Thomas; Lim, Yah Leng; Bertling, Karl; Ikonić, Zoran; Valavanis, Alexander; Dean, Paul; Cooper, Jonathan; Khanna, Suraj P; Lachab, Mohammad; Linfield, Edmund H; Davies, A Giles; Harrison, Paul; Indjin, Dragan; Rakić, Aleksandar D

2016-09-05

Optical feedback effects in lasers may be useful or problematic, depending on the type of application. When semiconductor lasers are operated using pulsed-mode excitation, their behavior under optical feedback depends on the electronic and thermal characteristics of the laser, as well as the nature of the external cavity. Predicting the behavior of a laser under both optical feedback and pulsed operation therefore requires a detailed model that includes laser-specific thermal and electronic characteristics. In this paper we introduce such a model for an exemplar bound-to-continuum terahertz frequency quantum cascade laser (QCL), illustrating its use in a selection of pulsed operation scenarios. Our results demonstrate significant interplay between electro-optical, thermal, and feedback phenomena, and that this interplay is key to understanding QCL behavior in pulsed applications. Further, our results suggest that for many types of QCL in interferometric applications, thermal modulation via low duty cycle pulsed operation would be an alternative to commonly used adiabatic modulation.

Design of a haptic device with grasp and push-pull force feedback for a master-slave surgical robot.

PubMed

Hu, Zhenkai; Yoon, Chae-Hyun; Park, Samuel Byeongjun; Jo, Yung-Ho

2016-07-01

We propose a portable haptic device providing grasp (kinesthetic) and push-pull (cutaneous) sensations for optical-motion-capture master interfaces. Although optical-motion-capture master interfaces for surgical robot systems can overcome the stiffness, friction, and coupling problems of mechanical master interfaces, it is difficult to add haptic feedback to an optical-motion-capture master interface without constraining the free motion of the operator's hands. Therefore, we utilized a Bowden cable-driven mechanism to provide the grasp and push-pull sensation while retaining the free hand motion of the optical-motion capture master interface. To evaluate the haptic device, we construct a 2-DOF force sensing/force feedback system. We compare the sensed force and the reproduced force of the haptic device. Finally, a needle insertion test was done to evaluate the performance of the haptic interface in the master-slave system. The results demonstrate that both the grasp force feedback and the push-pull force feedback provided by the haptic interface closely matched with the sensed forces of the slave robot. We successfully apply our haptic interface in the optical-motion-capture master-slave system. The results of the needle insertion test showed that our haptic feedback can provide more safety than merely visual observation. We develop a suitable haptic device to produce both kinesthetic grasp force feedback and cutaneous push-pull force feedback. Our future research will include further objective performance evaluations of the optical-motion-capture master-slave robot system with our haptic interface in surgical scenarios.

Experimental realization of a feedback optical parametric amplifier with four-wave mixing

NASA Astrophysics Data System (ADS)

Pan, Xiaozhou; Chen, Hui; Wei, Tianxiang; Zhang, Jun; Marino, Alberto M.; Treps, Nicolas; Glasser, Ryan T.; Jing, Jietai

2018-04-01

Optical parametric amplifiers (OPAs) play a fundamental role in the generation of quantum correlation for quantum information processing and quantum metrology. In order to increase the communication fidelity of the quantum information protocol and the measurement precision of quantum metrology, it requires a high degree of quantum correlation. In this Rapid Communication we report a feedback optical parametric amplifier that employs a four-wave mixing (FWM) process as the underlying OPA and a beam splitter as the feedback controller. We first construct a theoretical model for this feedback-based FWM process and experimentally study the effect of the feedback control on the quantum properties of the system. Specifically, we find that the quantum correlation between the output fields can be enhanced by tuning the strength of the feedback.

Cloud-radiation interactions - Effects of cirrus optical thickness feedbacks

NASA Technical Reports Server (NTRS)

Somerville, Richard C. J.; Iacobellis, Sam

1987-01-01

The paper is concerned with a cloud-radiation feedback mechanism which may be an important component of the climate changes expected from increased atmospheric concentrations of carbon dioxide and other trace greenhouse gases. A major result of the study is that cirrus cloud optical thickness feedbacks may indeed tend to increase the surface warming due to trace gas increases. However, the positive feedback from cirrus appears to be generally weaker than the negative effects due to lower clouds. The results just confirm those of earlier research indicating that the net effect of cloud optical thickness feedbacks may be a negative feedback which may substantially (by a factor of about 2) reduce the surface warming due to the doubling of CO2, even in the presence of cirrus clouds.

Fiber distributed feedback laser

NASA Technical Reports Server (NTRS)

Elachi, C.; Evans, G. A.; Yeh, C. (Inventor)

1976-01-01

Utilizing round optical fibers as communication channels in optical communication networks presents the problem of obtaining a high efficiency coupling between the optical fiber and the laser. A laser is made an integral part of the optical fiber channel by either diffusing active material into the optical fiber or surrounding the optical fiber with the active material. Oscillation within the active medium to produce lasing action is established by grating the optical fiber so that distributed feedback occurs.

Temperature feedback control for long-term carrier-envelope phase locking

DOEpatents

Chang, Zenghu [Manhattan, KS; Yun, Chenxia [Manhattan, KS; Chen, Shouyuan [Manhattan, KS; Wang, He [Manhattan, KS; Chini, Michael [Manhattan, KS

2012-07-24

A feedback control module for stabilizing a carrier-envelope phase of an output of a laser oscillator system comprises a first photodetector, a second photodetector, a phase stabilizer, an optical modulator, and a thermal control element. The first photodetector may generate a first feedback signal corresponding to a first portion of a laser beam from an oscillator. The second photodetector may generate a second feedback signal corresponding to a second portion of the laser beam filtered by a low-pass filter. The phase stabilizer may divide the frequency of the first feedback signal by a factor and generate an error signal corresponding to the difference between the frequency-divided first feedback signal and the second feedback signal. The optical modulator may modulate the laser beam within the oscillator corresponding to the error signal. The thermal control unit may change the temperature of the oscillator corresponding to a signal operable to control the optical modulator.

A Prototype Instrument for Adaptive SPECT Imaging

PubMed Central

Freed, Melanie; Kupinski, Matthew A.; Furenlid, Lars R.; Barrett, Harrison H.

2015-01-01

We have designed and constructed a small-animal adaptive SPECT imaging system as a prototype for quantifying the potential benefit of adaptive SPECT imaging over the traditional fixed geometry approach. The optical design of the system is based on filling the detector with the object for each viewing angle, maximizing the sensitivity, and optimizing the resolution in the projection images. Additional feedback rules for determining the optimal geometry of the system can be easily added to the existing control software. Preliminary data have been taken of a phantom with a small, hot, offset lesion in a flat background in both adaptive and fixed geometry modes. Comparison of the predicted system behavior with the actual system behavior is presented along with recommendations for system improvements. PMID:26346820

Toward guidance of epicardial cardiac radiofrequency ablation therapy using optical coherence tomography

NASA Astrophysics Data System (ADS)

Fleming, Christine P.; Quan, Kara J.; Rollins, Andrew M.

2010-07-01

Radiofrequency ablation (RFA) is the standard of care to cure many cardiac arrhythmias. Epicardial ablation for the treatment of ventricular tachycardia has limited success rates due in part to the presence of epicardial fat, which prevents proper rf energy delivery, inadequate contact of ablation catheter with tissue, and increased likelihood of complications with energy delivery in close proximity to coronary vessels. A method to directly visualize the epicardial surface during RFA could potentially provide feedback to reduce complications and titrate rf energy dose by detecting critical structures, assessing probe contact, and confirming energy delivery by visualizing lesion formation. Currently, there is no technology available for direct visualization of the heart surface during epicardial RFA therapy. We demonstrate that optical coherence tomography (OCT) imaging has the potential to fill this unmet need. Spectral domain OCT at 1310 nm is employed to image the epicardial surface of freshly excised swine hearts using a microscope integrated bench-top scanner and a forward imaging catheter probe. OCT image features are observed that clearly distinguish untreated myocardium, ablation lesions, epicardial fat, and coronary vessels, and assess tissue contact with catheter-based imaging. These results support the potential for real-time guidance of epicardial RFA therapy using OCT imaging.

Beam shaping in high-power broad-area quantum cascade lasers using optical feedback

PubMed Central

Ferré, Simon; Jumpertz, Louise; Carras, Mathieu; Ferreira, Robson; Grillot, Frédéric

2017-01-01

Broad-area quantum cascade lasers with high output powers are highly desirable sources for various applications including infrared countermeasures. However, such structures suffer from strongly deteriorated beam quality due to multimode behavior, diffraction of light and self-focusing. Quantum cascade lasers presenting high performances in terms of power and heat-load dissipation are reported and their response to a nonlinear control based on optical feedback is studied. Applying optical feedback enables to efficiently tailor its near-field beam profile. The different cavity modes are sequentially excited by shifting the feedback mirror angle. Further control of the near-field profile is demonstrated using spatial filtering. The impact of an inhomogeneous gain as well as the influence of the cavity width are investigated. Compared to existing technologies, that are complex and costly, beam shaping with optical feedback is a more flexible solution to obtain high-quality mid-infrared sources. PMID:28287175

Beam shaping in high-power broad-area quantum cascade lasers using optical feedback.

PubMed

Ferré, Simon; Jumpertz, Louise; Carras, Mathieu; Ferreira, Robson; Grillot, Frédéric

2017-03-13

Broad-area quantum cascade lasers with high output powers are highly desirable sources for various applications including infrared countermeasures. However, such structures suffer from strongly deteriorated beam quality due to multimode behavior, diffraction of light and self-focusing. Quantum cascade lasers presenting high performances in terms of power and heat-load dissipation are reported and their response to a nonlinear control based on optical feedback is studied. Applying optical feedback enables to efficiently tailor its near-field beam profile. The different cavity modes are sequentially excited by shifting the feedback mirror angle. Further control of the near-field profile is demonstrated using spatial filtering. The impact of an inhomogeneous gain as well as the influence of the cavity width are investigated. Compared to existing technologies, that are complex and costly, beam shaping with optical feedback is a more flexible solution to obtain high-quality mid-infrared sources.

Feasibility of a feedback control of atomic self-organization in an optical cavity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ivanov, D. A., E-mail: ivanov-den@yandex.ru; Ivanova, T. Yu.

Many interesting nonlinear effects are based on the strong interaction of motional degrees of freedom of atoms with an optical cavity field. Among them is the spatial self-organization of atoms in a pattern where the atoms group in either odd or even sites of the cavity-induced optical potential. An experimental observation of this effect can be simplified by using, along with the original cavity-induced feedback, an additional electronic feedback based on the detection of light leaking the cavity and the control of the optical potential for the atoms. Following our previous study, we show that this approach is more efficientmore » from the laser power perspective than the original scheme without the electronic feedback.« less

Parallel multiplex laser feedback interferometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Song; Tan, Yidong; Zhang, Shulian, E-mail: zsl-dpi@mail.tsinghua.edu.cn

2013-12-15

We present a parallel multiplex laser feedback interferometer based on spatial multiplexing which avoids the signal crosstalk in the former feedback interferometer. The interferometer outputs two close parallel laser beams, whose frequencies are shifted by two acousto-optic modulators by 2Ω simultaneously. A static reference mirror is inserted into one of the optical paths as the reference optical path. The other beam impinges on the target as the measurement optical path. Phase variations of the two feedback laser beams are simultaneously measured through heterodyne demodulation with two different detectors. Their subtraction accurately reflects the target displacement. Under typical room conditions, experimentalmore » results show a resolution of 1.6 nm and accuracy of 7.8 nm within the range of 100 μm.« less

Spatial frequency-dependent feedback of visual cortical area 21a modulating functional orientation column maps in areas 17 and 18 of the cat.

PubMed

Huang, Luoxiu; Chen, Xin; Shou, Tiande

2004-02-20

The feedback effect of activity of area 21a on orientation maps of areas 17 and 18 was investigated in cats using intrinsic signal optical imaging. A spatial frequency-dependent decrease in response amplitude of orientation maps to grating stimuli was observed in areas 17 and 18 when area 21a was inactivated by local injection of GABA, or by a lesion induced by liquid nitrogen freezing. The decrease in response amplitude of orientation maps of areas 17 and 18 after the area 21a inactivation paralleled the normal response without the inactivation. Application in area 21a of bicuculline, a GABAa receptor antagonist caused an increase in response amplitude of orientation maps of area 17. The results indicate a positive feedback from high-order visual cortical area 21a to lower-order areas underlying a spatial frequency-dependent mechanism.

Feedback and Acousto Optic Isolation Effects on Laser Stability.

DTIC Science & Technology

1977-03-01

This paper analyzes the effect of optical feedback on laser frequency stability and the acousto optic isolator concept, which was demonstrated...nonlinearity such as saturation in the laser medium. The analysis mathematically corroborates the initial acousto optic isolator concept and the...limited experimental data available. In the study of the acousto optic isolator, it was determined that an acceptable analytic expression for the

High-frequency chaotic dynamics enabled by optical phase-conjugation

PubMed Central

Mercier, Émeric; Wolfersberger, Delphine; Sciamanna, Marc

2016-01-01

Wideband chaos is of interest for applications such as random number generation or encrypted communications, which typically use optical feedback in a semiconductor laser. Here, we show that replacing conventional optical feedback with phase-conjugate feedback improves the chaos bandwidth. In the range of achievable phase-conjugate mirror reflectivities, the bandwidth increase reaches 27% when compared with feedback from a conventional mirror. Experimental measurements of the time-resolved frequency dynamics on nanosecond time-scales show that the bandwidth enhancement is related to the onset of self-pulsing solutions at harmonics of the external-cavity frequency. In the observed regime, the system follows a chaotic itinerancy among these destabilized high-frequency external-cavity modes. The recorded features are unique to phase-conjugate feedback and distinguish it from the long-standing problem of time-delayed feedback dynamics. PMID:26739806

Towards Mobile OCR: How To Take a Good Picture of a Document Without Sight.

PubMed

Cutter, Michael; Manduchi, Roberto

The advent of mobile OCR (optical character recognition) applications on regular smartphones holds great promise for enabling blind people to access printed information. Unfortunately, these systems suffer from a problem: in order for OCR output to be meaningful, a well-framed image of the document needs to be taken, something that is difficult to do without sight. This contribution presents an experimental investigation of how blind people position and orient a camera phone while acquiring document images. We developed experimental software to investigate if verbal guidance aids in the acquisition of OCR-readable images without sight. We report on our participant's feedback and performance before and after assistance from our software.

Towards Mobile OCR: How To Take a Good Picture of a Document Without Sight

PubMed Central

Cutter, Michael; Manduchi, Roberto

2015-01-01

The advent of mobile OCR (optical character recognition) applications on regular smartphones holds great promise for enabling blind people to access printed information. Unfortunately, these systems suffer from a problem: in order for OCR output to be meaningful, a well-framed image of the document needs to be taken, something that is difficult to do without sight. This contribution presents an experimental investigation of how blind people position and orient a camera phone while acquiring document images. We developed experimental software to investigate if verbal guidance aids in the acquisition of OCR-readable images without sight. We report on our participant's feedback and performance before and after assistance from our software. PMID:26677461

High frequency optoelectronic oscillators based on the optical feedback of semiconductor mode-locked laser diodes.

PubMed

Haji, Mohsin; Hou, Lianping; Kelly, Anthony E; Akbar, Jehan; Marsh, John H; Arnold, John M; Ironside, Charles N

2012-01-30

Optical self seeding feedback techniques can be used to improve the noise characteristics of passively mode-locked laser diodes. External cavities such as fiber optic cables can increase the memory of the phase and subsequently improve the timing jitter. In this work, an improved optical feedback architecture is proposed using an optical fiber loop delay as a cavity extension of the mode-locked laser. We investigate the effect of the noise reduction as a function of the loop length and feedback power. The well known composite cavity technique is also implemented for suppressing supermode noise artifacts presented due to harmonic mode locking effects. Using this method, we achieve a record low radio frequency linewidth of 192 Hz for any high frequency (>1 GHz) passively mode-locked laser to date (to the best of the authors' knowledge), making it promising for the development of high frequency optoelectronic oscillators.

Feedback effects in optical communication systems: characteristic curve for single-mode InGaAsP lasers.

PubMed

Brivio, F; Reverdito, C; Sacchi, G; Chiaretti, G; Milani, M

1992-08-20

An experimental analysis of InGaAsP injection lasers shows an unexpected decrease of the differential quantum efficiency as a function of injected current when optical power is fed back into the active cavity of a diode inserted into a long transmission line. To investigate the response of laser diodes to optical feedback, we base our analysis on a microscopic model, resulting in a set of coupled equations that include the microscopic parameters that characterize the material and the device. This description takes into account the nonlinear dependence of the interband carrier lifetime on the level of optical feedback. Good agreement between the analytical description and experimental data is obtained for threshold current and differential quantum efficiency as functions of the feedback ratio.

Enhanced weak-signal sensitivity in two-photon microscopy by adaptive illumination.

PubMed

Chu, Kengyeh K; Lim, Daryl; Mertz, Jerome

2007-10-01

We describe a technique to enhance both the weak-signal relative sensitivity and the dynamic range of a laser scanning optical microscope. The technique is based on maintaining a fixed detection power by fast feedback control of the illumination power, thereby transferring high measurement resolution to weak signals while virtually eliminating the possibility of image saturation. We analyze and demonstrate the benefits of adaptive illumination in two-photon fluorescence microscopy.

Precise measurement of single-mode fiber lengths using a gain-switched distributed feedback laser with delayed optical feedback.

PubMed

Wada, Kenji; Matsukura, Satoru; Tanaka, Amaka; Matsuyama, Tetsuya; Horinaka, Hiromichi

2015-09-07

A simple method to measure single-mode optical fiber lengths is proposed and demonstrated using a gain-switched 1.55-μm distributed feedback laser without a fast photodetector or an optical interferometer. From the variation in the amplified spontaneous emission noise intensity with respect to the modulation frequency of the gain switching, the optical length of a 1-km single-mode fiber immersed in water is found to be 1471.043915 m ± 33 μm, corresponding to a relative standard deviation of 2.2 × 10(-8). This optical length is an average value over a measurement time of one minute under ordinary laboratory conditions.

Transportable and vibration-free full-field low-coherent quantitative phase microscope

NASA Astrophysics Data System (ADS)

Yamauchi, Toyohiko; Yamada, Hidenao; Goto, Kentaro; Matsui, Hisayuki; Yasuhiko, Osamu; Ueda, Yukio

2018-02-01

We developed a transportable Linnik-type full-field low-coherent quantitative phase microscope that is able to compensate for optical path length (OPL) disturbance due to environmental mechanical noises. Though two-beam interferometers such as Linnik ones suffer from unstable OPL difference, we overcame this problem with a mechanical feedback system based on digital signal-processing that controls the OPL difference in sub-nanometer resolution precisely with a feedback bandwidth of 4 kHz. The developed setup has a footprint of 200 mm by 200 mm, a height of 500 mm, and a weight of 4.5 kilograms. In the transmission imaging mode, cells were cultured on a reflection-enhanced glass-bottom dish, and we obtained interference images sequentially while performing stepwise quarter-wavelength phase-shifting. Real-time image processing, including retrieval of the unwrapped phase from interference images and its background correction, along with the acquisition of interference images, was performed on a laptop computer. Emulation of the phase contrast (PhC) images and the differential interference contrast (DIC) images was also performed in real time. Moreover, our setup was applied for full-field cell membrane imaging in the reflection mode, where the cells were cultured on an anti-reflection (AR)-coated glass-bottom dish. The phase and intensity of the light reflected by the membrane revealed the outer shape of the cells independent of the refractive index. In this paper, we show imaging results on cultured cells in both transmission and reflection modes.

Image-guided smart laser system for precision implantation of cells in cartilage

NASA Astrophysics Data System (ADS)

Katta, Nitesh; Rector, John A.; Gardner, Michael R.; McElroy, Austin B.; Choy, Kevin C.; Crosby, Cody; Zoldan, Janet; Milner, Thomas E.

2017-03-01

State-of-the-art treatment for joint diseases like osteoarthritis focus on articular cartilage repair/regeneration by stem cell implantation therapy. However, the technique is limited by a lack of precision in the physician's imaging and cell deposition toolkit. We describe a novel combination of high-resolution, rapid scan-rate optical coherence tomography (OCT) alongside a short-pulsed nanosecond thulium (Tm) laser for precise cell seeding in cartilage. The superior beam quality of thulium lasers and wavelength of operation 1940 nm offers high volumetric tissue removal rates and minimizes the residual thermal footprint. OCT imaging enables targeted micro-well placement, precise cell deposition, and feature contrast. A bench-top system is constructed using a 15 W, 1940 nm, nanosecond-pulsed Tm fiber laser (500 μJ pulse energy, 100 ns pulse duration, 30kHz repetition rate) for removing tissue, and a swept source laser (1310 ± 70 nm, 100 kHz sweep rate) for OCT imaging, forming a combined Tm/OCT system - a "smart laser knife". OCT assists the smart laser knife user in characterizing cartilage to inform micro-well placement. The Tm laser creates micro-wells (2.35 mm diameter length, 1.5 mm width, 300 μm deep) and micro-incisions (1 mm wide, 200 μm deep) while OCT image-guidance assists and demonstrates this precision cutting and cell deposition with real-time feedback. To test micro-well creation and cell deposition protocol, gelatin phantoms are constructed mimicking cartilage optical properties and physiological structure. Cell viability is then assessed to illustrate the efficacy of the hydrogel deposition. Automated OCT feedback is demonstrated for cutting procedures to avoid important surface/subsurface structures. This bench-top smart laser knife system described here offers a new image-guided approach to precise stem cell seeding that can enhance the efficacy of articular cartilage repair.

Introductory review on `Flying Triangulation': a motion-robust optical 3D measurement principle

NASA Astrophysics Data System (ADS)

Ettl, Svenja

2015-04-01

'Flying Triangulation' (FlyTri) is a recently developed principle which allows for a motion-robust optical 3D measurement of rough surfaces. It combines a simple sensor with sophisticated algorithms: a single-shot sensor acquires 2D camera images. From each camera image, a 3D profile is generated. The series of 3D profiles generated are aligned to one another by algorithms, without relying on any external tracking device. It delivers real-time feedback of the measurement process which enables an all-around measurement of objects. The principle has great potential for small-space acquisition environments, such as the measurement of the interior of a car, and motion-sensitive measurement tasks, such as the intraoral measurement of teeth. This article gives an overview of the basic ideas and applications of FlyTri. The main challenges and their solutions are discussed. Measurement examples are also given to demonstrate the potential of the measurement principle.

Review of intraoperative optical coherence tomography: technology and applications [Invited

PubMed Central

Carrasco-Zevallos, Oscar M.; Viehland, Christian; Keller, Brenton; Draelos, Mark; Kuo, Anthony N.; Toth, Cynthia A.; Izatt, Joseph A.

2017-01-01

During microsurgery, en face imaging of the surgical field through the operating microscope limits the surgeon’s depth perception and visualization of instruments and sub-surface anatomy. Surgical procedures outside microsurgery, such as breast tumor resections, may also benefit from visualization of the sub-surface tissue structures. The widespread clinical adoption of optical coherence tomography (OCT) in ophthalmology and its growing prominence in other fields, such as cancer imaging, has motivated the development of intraoperative OCT for real-time tomographic visualization of surgical interventions. This article reviews key technological developments in intraoperative OCT and their applications in human surgery. We focus on handheld OCT probes, microscope-integrated OCT systems, and OCT-guided laser treatment platforms designed for intraoperative use. Moreover, we discuss intraoperative OCT adjuncts and processing techniques currently under development to optimize the surgical feedback derivable from OCT data. Lastly, we survey salient clinical studies of intraoperative OCT for human surgery. PMID:28663853

Deformable Surface Accommodating Intraocular Lens: Second Generation Prototype Design Methodology and Testing.

PubMed

McCafferty, Sean J; Schwiegerling, Jim T

2015-04-01

Present an analysis methodology for developing and evaluating accommodating intraocular lenses incorporating a deformable interface. The next generation design of extruded gel interface intraocular lens is presented. A prototype based upon similar previously in vivo proven design was tested with measurements of actuation force, lens power, interface contour, optical transfer function, and visual Strehl ratio. Prototype verified mathematical models were used to optimize optical and mechanical design parameters to maximize the image quality and minimize the required force to accommodate. The prototype lens produced adequate image quality with the available physiologic accommodating force. The iterative mathematical modeling based upon the prototype yielded maximized optical and mechanical performance through maximum allowable gel thickness to extrusion diameter ratio, maximum feasible refractive index change at the interface, and minimum gel material properties in Poisson's ratio and Young's modulus. The design prototype performed well. It operated within the physiologic constraints of the human eye including the force available for full accommodative amplitude using the eye's natural focusing feedback, while maintaining image quality in the space available. The parameters that optimized optical and mechanical performance were delineated as those, which minimize both asphericity and actuation pressure. The design parameters outlined herein can be used as a template to maximize the performance of a deformable interface intraocular lens. The article combines a multidisciplinary basic science approach from biomechanics, optical science, and ophthalmology to optimize an intraocular lens design suitable for preliminary animal trials.

Nanopositioning for polarimetric characterization.

PubMed

Qureshi, Naser; Kolokoltsev, Oleg V; Ortega-Martínez, Roberto; Ordoñez-Romero, C L

2008-12-01

A positioning system with approximately nanometer resolution has been developed based on a new implementation of a motor-driven screw scheme. In contrast to conventional positioning systems based on piezoelectric elements, this system shows remarkably low levels of drift and vibration, and eliminates the need for position feedback during typical data acquisition processes. During positioning or scanning processes, non-repeatability and hysteresis problems inherent in mechanical positioning systems are greatly reduced using a software feedback scheme. As a result, we are able to demonstrate an average mechanical resolution of 1.45 nm and near diffraction-limited imaging using scanning optical microscopy. We propose this approach to nanopositioning as a readily accessible alternative enabling high spatial resolution scanning probe characterization (e.g., polarimetry) and provide practical details for its implementation.

Nonlinear filter based decision feedback equalizer for optical communication systems.

PubMed

Han, Xiaoqi; Cheng, Chi-Hao

2014-04-07

Nonlinear impairments in optical communication system have become a major concern of optical engineers. In this paper, we demonstrate that utilizing a nonlinear filter based Decision Feedback Equalizer (DFE) with error detection capability can deliver a better performance compared with the conventional linear filter based DFE. The proposed algorithms are tested in simulation using a coherent 100 Gb/sec 16-QAM optical communication system in a legacy optical network setting.

The Large Ultraviolet/Optical/Infrared Surveyor (LUVOIR)

NASA Astrophysics Data System (ADS)

Peterson, Bradley M.; Fischer, Debra; LUVOIR Science and Technology Definition Team

2017-01-01

LUVOIR is one of four potential large mission concepts for which the NASA Astrophysics Division has commissioned studies by Science and Technology Definition Teams (STDTs) drawn from the astronomical community. LUVOIR will have an 8 to16-m segmented primary mirror and operate at the Sun-Earth L2 point. It will be designed to support a broad range of astrophysics and exoplanet studies. The notional initial complement of instruments will include 1) a high-performance optical/NIR coronagraph with imaging and spectroscopic capability, 2) a UV imager and spectrograph with high spectral resolution and multi-object capability, 3) a high-definition wide-field optical/NIR camera, and 4) a multi-resolution optical/NIR spectrograph. LUVOIR will be designed for extreme stability to support unprecedented spatial resolution and coronagraphy. It is intended to be a long-lifetime facility that is both serviceable and upgradable. This is the first report by the LUVOIR STDT to the community on the top-level architectures we are studying, including preliminary capabilities of a mission with those parameters. The STDT seeks feedback from the astronomical community for key science investigations that can be undertaken with the notional instrument suite and to identify desirable capabilities that will enable additional key science.

Good vibrations: Controlling light with sound (Conference Presentation)

NASA Astrophysics Data System (ADS)

Eggleton, Benjamin J.; Choudhary, Amol

2016-10-01

One of the surprises of nonlinear optics, is that light may interact strongly with sound. Intense laser light literally "shakes" the glass in optical fibres, exciting acoustic waves (sound) in the fibre. Under the right conditions, it leads to a positive feedback loop between light and sound termed "Stimulated Brillouin Scattering," or simply SBS. This nonlinear interaction can amplify or filter light waves with extreme precision in frequency which makes it uniquely suited to solve key problems in the fields of defence, biomedicine, wireless communications, spectroscopy and imaging. We have achieved the first demonstration of SBS in compact chip-scale structures, carefully designed so that the optical fields and the acoustic fields are simultaneously confined and guided. This new platform has opened a range of new functionalities that are being applied in communications and defence with breathtaking performance and compactness. My talk will introduce this new field and review our progress and achievements, including silicon based optical phononic processor.

Adaptive electron beam shaping using a photoemission gun and spatial light modulator

NASA Astrophysics Data System (ADS)

Maxson, Jared; Lee, Hyeri; Bartnik, Adam C.; Kiefer, Jacob; Bazarov, Ivan

2015-02-01

The need for precisely defined beam shapes in photoelectron sources has been well established. In this paper, we use a spatial light modulator and simple shaping algorithm to create arbitrary, detailed transverse laser shapes with high fidelity. We transmit this shaped laser to the photocathode of a high voltage dc gun. Using beam currents where space charge is negligible, and using an imaging solenoid and fluorescent viewscreen, we show that the resultant beam shape preserves these detailed features with similar fidelity. Next, instead of transmitting a shaped laser profile, we use an active feedback on the unshaped electron beam image to create equally accurate and detailed shapes. We demonstrate that this electron beam feedback has the added advantage of correcting for electron optical aberrations, yielding shapes without skew. The method may serve to provide precisely defined electron beams for low current target experiments, space-charge dominated beam commissioning, as well as for online adaptive correction of photocathode quantum efficiency degradation.

Constraining the low-cloud optical depth feedback at middle and high latitudes using satellite observations

DOE PAGES

Terai, C. R.; Klein, S. A.; Zelinka, M. D.

2016-08-26

The increase in cloud optical depth with warming at middle and high latitudes is a robust cloud feedback response found across all climate models. This study builds on results that suggest the optical depth response to temperature is timescale invariant for low-level clouds. The timescale invariance allows one to use satellite observations to constrain the models' optical depth feedbacks. Three passive-sensor satellite retrievals are compared against simulations from eight models from the Atmosphere Model Intercomparison Project (AMIP) of the 5th Coupled Model Intercomparison Project (CMIP5). This study confirms that the low-cloud optical depth response is timescale invariant in the AMIPmore » simulations, generally at latitudes higher than 40°. Compared to satellite estimates, most models overestimate the increase in optical depth with warming at the monthly and interannual timescales. Many models also do not capture the increase in optical depth with estimated inversion strength that is found in all three satellite observations and in previous studies. The discrepancy between models and satellites exists in both hemispheres and in most months of the year. A simple replacement of the models' optical depth sensitivities with the satellites' sensitivities reduces the negative shortwave cloud feedback by at least 50% in the 40°–70°S latitude band and by at least 65% in the 40°–70°N latitude band. Furthermore, based on this analysis of satellite observations, we conclude that the low-cloud optical depth feedback at middle and high latitudes is likely too negative in climate models.« less

Constraining the low-cloud optical depth feedback at middle and high latitudes using satellite observations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Terai, C. R.; Klein, S. A.; Zelinka, M. D.

The increase in cloud optical depth with warming at middle and high latitudes is a robust cloud feedback response found across all climate models. This study builds on results that suggest the optical depth response to temperature is timescale invariant for low-level clouds. The timescale invariance allows one to use satellite observations to constrain the models' optical depth feedbacks. Three passive-sensor satellite retrievals are compared against simulations from eight models from the Atmosphere Model Intercomparison Project (AMIP) of the 5th Coupled Model Intercomparison Project (CMIP5). This study confirms that the low-cloud optical depth response is timescale invariant in the AMIPmore » simulations, generally at latitudes higher than 40°. Compared to satellite estimates, most models overestimate the increase in optical depth with warming at the monthly and interannual timescales. Many models also do not capture the increase in optical depth with estimated inversion strength that is found in all three satellite observations and in previous studies. The discrepancy between models and satellites exists in both hemispheres and in most months of the year. A simple replacement of the models' optical depth sensitivities with the satellites' sensitivities reduces the negative shortwave cloud feedback by at least 50% in the 40°–70°S latitude band and by at least 65% in the 40°–70°N latitude band. Furthermore, based on this analysis of satellite observations, we conclude that the low-cloud optical depth feedback at middle and high latitudes is likely too negative in climate models.« less

Scalable ranked retrieval using document images

NASA Astrophysics Data System (ADS)

Jain, Rajiv; Oard, Douglas W.; Doermann, David

2013-12-01

Despite the explosion of text on the Internet, hard copy documents that have been scanned as images still play a significant role for some tasks. The best method to perform ranked retrieval on a large corpus of document images, however, remains an open research question. The most common approach has been to perform text retrieval using terms generated by optical character recognition. This paper, by contrast, examines whether a scalable segmentation-free image retrieval algorithm, which matches sub-images containing text or graphical objects, can provide additional benefit in satisfying a user's information needs on a large, real world dataset. Results on 7 million scanned pages from the CDIP v1.0 test collection show that content based image retrieval finds a substantial number of documents that text retrieval misses, and that when used as a basis for relevance feedback can yield improvements in retrieval effectiveness.

Intracavity optical trapping with Ytterbium doped fiber ring laser

NASA Astrophysics Data System (ADS)

Sayed, Rania; Kalantarifard, Fatemeh; Elahi, Parviz; Ilday, F. Omer; Volpe, Giovanni; Maragò, Onofrio M.

2013-09-01

We propose a novel approach for trapping micron-sized particles and living cells based on optical feedback. This approach can be implemented at low numerical aperture (NA=0.5, 20X) and long working distance. In this configuration, an optical tweezers is constructed inside a ring cavity fiber laser and the optical feedback in the ring cavity is controlled by the light scattered from a trapped particle. In particular, once the particle is trapped, the laser operation, optical feedback and intracavity power are affected by the particle motion. We demonstrate that using this configuration is possible to stably hold micron-sized particles and single living cells in the focal spot of the laser beam. The calibration of the optical forces is achieved by tracking the Brownian motion of a trapped particle or cell and analysing its position distribution.

In-cell overlay metrology by using optical metrology tool

NASA Astrophysics Data System (ADS)

Lee, Honggoo; Han, Sangjun; Hong, Minhyung; Kim, Seungyoung; Lee, Jieun; Lee, DongYoung; Oh, Eungryong; Choi, Ahlin; Park, Hyowon; Liang, Waley; Choi, DongSub; Kim, Nakyoon; Lee, Jeongpyo; Pandev, Stilian; Jeon, Sanghuck; Robinson, John C.

2018-03-01

Overlay is one of the most critical process control steps of semiconductor manufacturing technology. A typical advanced scheme includes an overlay feedback loop based on after litho optical imaging overlay metrology on scribeline targets. The after litho control loop typically involves high frequency sampling: every lot or nearly every lot. An after etch overlay metrology step is often included, at a lower sampling frequency, in order to characterize and compensate for bias. The after etch metrology step often involves CD-SEM metrology, in this case in-cell and ondevice. This work explores an alternative approach using spectroscopic ellipsometry (SE) metrology and a machine learning analysis technique. Advanced 1x nm DRAM wafers were prepared, including both nominal (POR) wafers with mean overlay offsets, as well as DOE wafers with intentional across wafer overlay modulation. After litho metrology was measured using optical imaging metrology, as well as after etch metrology using both SE and CD-SEM for comparison. We investigate 2 types of machine learning techniques with SE data: model-less and model-based, showing excellent performance for after etch in-cell on-device overlay metrology.

Multimodal biophotonic workstation for live cell analysis.

PubMed

Esseling, Michael; Kemper, Björn; Antkowiak, Maciej; Stevenson, David J; Chaudet, Lionel; Neil, Mark A A; French, Paul W; von Bally, Gert; Dholakia, Kishan; Denz, Cornelia

2012-01-01

A reliable description and quantification of the complex physiology and reactions of living cells requires a multimodal analysis with various measurement techniques. We have investigated the integration of different techniques into a biophotonic workstation that can provide biological researchers with these capabilities. The combination of a micromanipulation tool with three different imaging principles is accomplished in a single inverted microscope which makes the results from all the techniques directly comparable. Chinese Hamster Ovary (CHO) cells were manipulated by optical tweezers while the feedback was directly analyzed by fluorescence lifetime imaging, digital holographic microscopy and dynamic phase-contrast microscopy. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Cherenkov imaging for Total Skin Electron Therapy (TSET)

NASA Astrophysics Data System (ADS)

Xie, Yunhe; Petroccia, Heather; Maity, Amit; Miao, Tianshun; Zhu, Yihua; Bruza, Petr; Pogue, Brian W.; Andreozzi, Jacqueline M.; Plastaras, John P.; Dong, Lei; Zhu, Timothy C.

2018-03-01

Total Skin Electron Therapy (TSET) utilizes high-energy electrons to treat cancers on the entire body surface. The otherwise invisible radiation beam can be observed via the optical Cherenkov photons emitted from interaction between the high-energy electron beam and tissue. Using a specialized camera-system, the Cherenkov emission can thus be used to evaluate the dose uniformity on the surface of the patient in real-time. Each patient was also monitored during TSET via in-vivo detectors (IVD) in nine locations. Patients undergoing TSET in various conditions (whole body and half body) were imaged and analyzed, and the viability of the system to provide clinical feedback was established.

Cherenkov imaging during volumetric modulated arc therapy for real-time radiation beam tracking and treatment response monitoring

NASA Astrophysics Data System (ADS)

Andreozzi, Jacqueline M.; Zhang, Rongxiao; Glaser, Adam K.; Gladstone, David J.; Jarvis, Lesley A.; Pogue, Brian W.

2016-03-01

External beam radiotherapy utilizes high energy radiation to target cancer with dynamic, patient-specific treatment plans. The otherwise invisible radiation beam can be observed via the optical Cherenkov photons emitted from interaction between the high energy beam and tissue. Using a specialized camera-system, the Cherenkov emission can thus be used to track the radiation beam on the surface of the patient in real-time, even for complex cases such as volumetric modulated arc therapy (VMAT). Two patients undergoing VMAT of the head and neck were imaged and analyzed, and the viability of the system to provide clinical feedback was established.

Operation of a separated-type x-ray interferometer for phase-contrast x-ray imaging

NASA Astrophysics Data System (ADS)

Yoneyama, Akio; Momose, Atsushi; Seya, Eiichi; Hirano, Keiichi; Takeda, Tohoru; Itai, Yuji

1999-12-01

Aiming at large-area phase-contrast x-ray imaging, a separated-type x-ray interferometer system was designed and developed to produce 25×20 mm interference patterns. The skew-symmetric optical system was adopted because of the feasibility of alignment. The rotation between the separated crystal blocks was controlled within a drift of 0.06 nrad using a feedback positioning system. This interferometer generated a 25×15 mm interference pattern with 0.07 nm synchrotron x-rays. A slice of a rabbit's kidney was observed, and its tubular structure could be revealed in a measured phase map.

Free-space optics mode-wavelength division multiplexing system using LG modes based on decision feedback equalization

NASA Astrophysics Data System (ADS)

Amphawan, Angela; Ghazi, Alaan; Al-dawoodi, Aras

2017-11-01

A free-space optics mode-wavelength division multiplexing (MWDM) system using Laguerre-Gaussian (LG) modes is designed using decision feedback equalization for controlling mode coupling and combating inter symbol interference so as to increase channel diversity. In this paper, a data rate of 24 Gbps is achieved for a FSO MWDM channel of 2.6 km in length using feedback equalization. Simulation results show significant improvement in eye diagrams and bit-error rates before and after decision feedback equalization.

Optical feedback in dfb quantum cascade laser for mid-infrared cavity ring-down spectroscopy

NASA Astrophysics Data System (ADS)

Terabayashi, Ryohei; Sonnenschein, Volker; Tomita, Hideki; Hayashi, Noriyoshi; Kato, Shusuke; Jin, Lei; Yamanaka, Masahito; Nishizawa, Norihiko; Sato, Atsushi; Nozawa, Kohei; Hashizume, Kenta; Oh-hara, Toshinari; Iguchi, Tetsuo

2017-11-01

A simple external optical feedback system has been applied to a distributed feedback quantum cascade laser (DFB QCL) for cavity ring-down spectroscopy (CRDS) and a clear effect of feedback was observed. A long external feedback path length of up to 4m can decrease the QCL linewidth to around 50kHz, which is of the order of the transmission linewidth of our high finesse ring-down cavity. The power spectral density of the transmission signal from high finesse cavity reveals that the noise at frequencies above 20kHz is reduced dramatically.

Thermo-optic locking of a semiconductor laser to a microcavity resonance.

PubMed

McRae, T G; Lee, Kwan H; McGovern, M; Gwyther, D; Bowen, W P

2009-11-23

We experimentally demonstrate thermo-optic locking of a semiconductor laser to an integrated toroidal optical microcavity. The lock is maintained for time periods exceeding twelve hours, without requiring any electronic control systems. Fast control is achieved by optical feedback induced by scattering centers within the microcavity, with thermal locking due to optical heating maintaining constructive interference between the cavity and the laser. Furthermore, the optical feedback acts to narrow the laser linewidth, with ultra high quality microtoroid resonances offering the potential for ultralow linewidth on-chip lasers.

Opto-electronic oscillators having optical resonators

NASA Technical Reports Server (NTRS)

Yao, Xiaotian Steve (Inventor); Maleki, Lutfollah (Inventor); Ilchenko, Vladimir (Inventor)

2003-01-01

Systems and techniques of incorporating an optical resonator in an optical part of a feedback loop in opto-electronic oscillators. This optical resonator provides a sufficiently long energy storage time and hence to produce an oscillation of a narrow linewidth and low phase noise. Certain mode matching conditions are required. For example, the mode spacing of the optical resonator is equal to one mode spacing, or a multiplicity of the mode spacing, of an opto-electronic feedback loop that receives a modulated optical signal and to produce an electrical oscillating signal.

Equalization for a page-oriented optical memory system

NASA Astrophysics Data System (ADS)

Trelewicz, Jennifer Q.; Capone, Jeffrey

1999-11-01

In this work, a method of decision-feedback equalization is developed for a digital holographic channel that experiences moderate-to-severe imaging errors. Decision feedback is utilized, not only where the channel is well-behaved, but also near the edges of the camera grid that are subject to a high degree of imaging error. In addition to these effects, the channel is worsened by typical problems of holographic channels, including non-uniform illumination, dropouts, and stuck bits. The approach described in this paper builds on established methods for performing trained and blind equalization on time-varying channels. The approach is tested on experimental data sets. On most of these data sets, the method of equalization described in this work delivers at least an order of magnitude improvement in bit-error rate (BER) before error-correction coding (ECC). When ECC is introduced, the approach is able to recover stored data with no errors for many of the tested data sets. Furthermore, a low BER was maintained even over a range of small alignment perturbations in the system. It is believed that this equalization method can allow cost reductions to be made in page-memory systems, by allowing for a larger image area per page or less complex imaging components, without sacrificing the low BER required by data storage applications.

A Study of Tropical thin Cirrus Clouds with Supervised Learning

NASA Astrophysics Data System (ADS)

Rodier, S. D.; Hu, Y.; Vaughan, M. A.

2007-12-01

ABSTRACT Accurate knowledge of the temporal frequency and spatial extent of optically thin cirrus is crucial to climate feedback analysis. Current global warming theory asserts that when the atmospheric concentration of CO2 increases, the outgoing longwave radiation at non-window wavelengths is reduced. If the Earth's net radiative balance is to remain stable, ground temperatures must rise in response, thereby increasing thermal emission to space. Current models do not account for subsequent changes in cloud cover, because this aspect of the climate feedback system is so poorly understood. One possible response of the cloud-climate feedback process is an increase in the global occurrence of thin cirrus clouds, driven by the increase in longwave cooling in the upper troposphere that results from higher CO2 concentrations. Exacerbating the difficulty of assessing the situation is the fact that passive remote sensing instruments cannot reliably detect cirrus clouds with optical depths less than ~0.3, because these clouds do not reflect enough sunlight to create a sufficient contrast with the Earth's surface. Now, however, the presence of thin cirrus can for the first time be accurately detected and systematically monitored by the combination of active and passive sensors onboard the CALIPSO satellite. Nevertheless, the data record is still quite limited, as CALIPSO has been in orbit for only 16 months. We have therefore initiated a multi-platform data fusion study to establish a methodology for extending the limited set of CALIPSO measurements to the existing 30-year record of passive remote sensing data, and thus improve our understanding of cloud feedback mechanisms. Using nighttime data from the first 10 days in April 2007 as a training set, we applied a general regression neural network (GRNN) to collocated samples of sea surface temperature (SST) reported by AMSR, brightness temperatures (BT) from the CALIPSO imaging infrared radiometer (IIR), and optical depths (OD) derived from the CALIPSO lidar measurements. The result is an accurate mapping of the optical depths derived from the active sensors to the brightness temperatures computed from the passive sensor measurements. Applying the trained network to this combination of passive sensor parameters, optical depths as small as 0.1 can be reliably retrieved. The relative uncertainties in the retrieval are reasonable, and can be improved significantly by use of a much larger training set.

Low-noise and high-speed photodetection system using optical feedback with a current amplification function

NASA Astrophysics Data System (ADS)

Akiba, M.

2015-09-01

A photodetection system with an optical-feedback circuit accompanied by current amplification was fabricated to minimize the drawbacks associated with a transimpedance amplifier (TIA) with a very high resistance feedback resistor. Current amplification was implemented by extracting an output light from the same light source that emitted the feedback light. The current gain corresponds to the ratio of the photocurrent created by the output light to that created by the feedback light because the feedback current value is identical to the input photocurrent value generated by an input light to be measured. The current gain has no theoretical limit. The output light was detected by a photodiode with a TIA having a small feedback resistance. The expression for the input-referred noise current of the optical-feedback photodetection system was derived, and the trade-off between sensitivity and response, which is a characteristic of TIA, was found to considerably improve. An optical-feedback photodetection system with an InGaAs pin photodiode was fabricated. The measured noise equivalent power of the system was 1.7 fW/Hz1/2 at 10 Hz and 1.3 μm, which is consistent with the derived expression. The time response of the system was found to deteriorate with decreasing photocurrent. The 50% rise time for a light pulse input increased from 3.1 μs at a photocurrent of 10 nA to 15 μs at photocurrents below 10 pA. The bandwidth of the input-referred noise current was 7 kHz, which is consistent with rise times below 10 pA.

Low-noise and high-speed photodetection system using optical feedback with a current amplification function.

PubMed

Akiba, M

2015-09-01

A photodetection system with an optical-feedback circuit accompanied by current amplification was fabricated to minimize the drawbacks associated with a transimpedance amplifier (TIA) with a very high resistance feedback resistor. Current amplification was implemented by extracting an output light from the same light source that emitted the feedback light. The current gain corresponds to the ratio of the photocurrent created by the output light to that created by the feedback light because the feedback current value is identical to the input photocurrent value generated by an input light to be measured. The current gain has no theoretical limit. The output light was detected by a photodiode with a TIA having a small feedback resistance. The expression for the input-referred noise current of the optical-feedback photodetection system was derived, and the trade-off between sensitivity and response, which is a characteristic of TIA, was found to considerably improve. An optical-feedback photodetection system with an InGaAs pin photodiode was fabricated. The measured noise equivalent power of the system was 1.7 fW/Hz(1/2) at 10 Hz and 1.3 μm, which is consistent with the derived expression. The time response of the system was found to deteriorate with decreasing photocurrent. The 50% rise time for a light pulse input increased from 3.1 μs at a photocurrent of 10 nA to 15 μs at photocurrents below 10 pA. The bandwidth of the input-referred noise current was 7 kHz, which is consistent with rise times below 10 pA.

A high spatial resolution X-ray and Hα study of hot gas in the halos of star-forming disk galaxies -- testing feedback models

NASA Astrophysics Data System (ADS)

Strickland, D. K.; Heckman, T. M.; Colbert, E. J. M.; Hoopes, C. G.; Weaver, K. A.

2002-12-01

We present arcsecond resolution Chandra X-ray and ground-based optical Hα imaging of a sample of ten edge-on star-forming disk galaxies (seven starburst and three ``normal'' spiral galaxies), a sample which covers the full range of star-formation intensity found in disk galaxies. The X-ray observations make use of the unprecented spatial resolution of the Chandra X-ray observatory to robustly remove X-ray emission from point sources, and hence obtain the X-ray properties of the diffuse thermal emission alone. This data has been combined with existing, comparable-resolution, ground-based Hα imaging. We compare these empirically-derived diffuse X-ray properties with various models for the generation of hot gas in the halos of star-forming galaxies: supernova feedback-based models (starburst-driven winds, galactic fountains), cosmologically-motivated accretion of the IGM and AGN-driven winds. SN feedback models best explain the observed diffuse X-ray emission. We then use the data to test basic, but fundamental, aspects of wind and fountain theories, e.g. the critical energy required for disk "break-out." DKS is supported by NASA through Chandra Postdoctoral Fellowship Award Number PF0-10012.

Tracking scanning laser ophthalmoscope (TSLO)

NASA Astrophysics Data System (ADS)

Hammer, Daniel X.; Ferguson, R. Daniel; Magill, John C.; White, Michael A.; Elsner, Ann E.; Webb, Robert H.

2003-07-01

The effectiveness of image stabilization with a retinal tracker in a multi-function, compact scanning laser ophthalmoscope (TSLO) was demonstrated in initial human subject tests. The retinal tracking system uses a confocal reflectometer with a closed loop optical servo system to lock onto features in the fundus. The system is modular to allow configuration for many research and clinical applications, including hyperspectral imaging, multifocal electroretinography (MFERG), perimetry, quantification of macular and photo-pigmentation, imaging of neovascularization and other subretinal structures (drusen, hyper-, and hypo-pigmentation), and endogenous fluorescence imaging. Optical hardware features include dual wavelength imaging and detection, integrated monochromator, higher-order motion control, and a stimulus source. The system software consists of a real-time feedback control algorithm and a user interface. Software enhancements include automatic bias correction, asymmetric feature tracking, image averaging, automatic track re-lock, and acquisition and logging of uncompressed images and video files. Normal adult subjects were tested without mydriasis to optimize the tracking instrumentation and to characterize imaging performance. The retinal tracking system achieves a bandwidth of greater than 1 kHz, which permits tracking at rates that greatly exceed the maximum rate of motion of the human eye. The TSLO stabilized images in all test subjects during ordinary saccades up to 500 deg/sec with an inter-frame accuracy better than 0.05 deg. Feature lock was maintained for minutes despite subject eye blinking. Successful frame averaging allowed image acquisition with decreased noise in low-light applications. The retinal tracking system significantly enhances the imaging capabilities of the scanning laser ophthalmoscope.

Monitoring photodynamic therapy of head and neck malignancies with optical spectroscopies

PubMed Central

Sunar, Ulas

2013-01-01

In recent years there has been significant developments in photosensitizers (PSs), light sources and light delivery systems that have allowed decreasing the treatment time and skin phototoxicity resulting in more frequent use of photodynamic therapy (PDT) in the clinical settings. Compared to standard treatment approaches such as chemo-radiation and surgery, PDT has much reduced morbidity for head and neck malignancies and is becoming an alternative treatment option. It can be used as an adjunct therapy to other treatment modalities without any additive cumulative side effects. Surface illumination can be an option for pre-malignant and early-stage malignancies while interstitial treatment is for debulking of thick tumors in the head and neck region. PDT can achieve equivalent or greater efficacy in treating head and neck malignancies, suggesting that it may be considered as a first line therapy in the future. Despite progressive development, clinical PDT needs improvement in several topics for wider acceptance including standardization of protocols that involve the same administrated light and PS doses and establishing quantitative tools for PDT dosimetry planning and response monitoring. Quantitative measures such as optical parameters, PS concentration, tissue oxygenation and blood flow are essential for accurate PDT dosimetry as well as PDT response monitoring and assessing therapy outcome. Unlike conventional imaging modalities like magnetic resonance imaging, novel optical imaging techniques can quantify PDT-related parameters without any contrast agent administration and enable real-time assessment during PDT for providing fast feedback to clinicians. Ongoing developments in optical imaging offer the promise of optimization of PDT protocols with improved outcomes. PMID:24303476

Wavefront Sensing With Switched Lenses for Defocus Diversity

NASA Technical Reports Server (NTRS)

Dean, Bruce H.

2007-01-01

In an alternative hardware design for an apparatus used in image-based wavefront sensing, defocus diversity is introduced by means of fixed lenses that are mounted in a filter wheel (see figure) so that they can be alternately switched into a position in front of the focal plane of an electronic camera recording the image formed by the optical system under test. [The terms image-based, wavefront sensing, and defocus diversity are defined in the first of the three immediately preceding articles, Broadband Phase Retrieval for Image-Based Wavefront Sensing (GSC-14899-1).] Each lens in the filter wheel is designed so that the optical effect of placing it at the assigned position is equivalent to the optical effect of translating the camera a specified defocus distance along the optical axis. Heretofore, defocus diversity has been obtained by translating the imaging camera along the optical axis to various defocus positions. Because data must be taken at multiple, accurately measured defocus positions, it is necessary to mount the camera on a precise translation stage that must be calibrated for each defocus position and/or to use an optical encoder for measurement and feedback control of the defocus positions. Additional latency is introduced into the wavefront sensing process as the camera is translated to the various defocus positions. Moreover, if the optical system under test has a large focal length, the required defocus values are large, making it necessary to use a correspondingly bulky translation stage. By eliminating the need for translation of the camera, the alternative design simplifies and accelerates the wavefront-sensing process. This design is cost-effective in that the filterwheel/lens mechanism can be built from commercial catalog components. After initial calibration of the defocus value of each lens, a selected defocus value is introduced by simply rotating the filter wheel to place the corresponding lens in front of the camera. The rotation of the wheel can be automated by use of a motor drive, and further calibration is not necessary. Because a camera-translation stage is no longer needed, the size of the overall apparatus can be correspondingly reduced.

Image quality assessment for video stream recognition systems

NASA Astrophysics Data System (ADS)

Chernov, Timofey S.; Razumnuy, Nikita P.; Kozharinov, Alexander S.; Nikolaev, Dmitry P.; Arlazarov, Vladimir V.

2018-04-01

Recognition and machine vision systems have long been widely used in many disciplines to automate various processes of life and industry. Input images of optical recognition systems can be subjected to a large number of different distortions, especially in uncontrolled or natural shooting conditions, which leads to unpredictable results of recognition systems, making it impossible to assess their reliability. For this reason, it is necessary to perform quality control of the input data of recognition systems, which is facilitated by modern progress in the field of image quality evaluation. In this paper, we investigate the approach to designing optical recognition systems with built-in input image quality estimation modules and feedback, for which the necessary definitions are introduced and a model for describing such systems is constructed. The efficiency of this approach is illustrated by the example of solving the problem of selecting the best frames for recognition in a video stream for a system with limited resources. Experimental results are presented for the system for identity documents recognition, showing a significant increase in the accuracy and speed of the system under simulated conditions of automatic camera focusing, leading to blurring of frames.

Hybrid surgical guidance based on the integration of radionuclear and optical technologies

PubMed Central

Valdés-Olmos, Renato; Buckle, Tessa; Vidal-Sicart, Sergi

2016-01-01

With the evolution of imaging technologies and tracers, the applications for nuclear molecular imaging are growing rapidly. For example, nuclear medicine is increasingly being used to guide surgical resections in complex anatomical locations. Here, a future workflow is envisioned that uses a combination of pre-operative diagnostics, navigation and intraoperative guidance. Radioguidance can provide means for pre-operative and intraoperative identification of “hot” lesions, forming the basis of a virtual data set that can be used for navigation. Luminescence guidance has shown great potential in the intraoperative setting by providing optical feedback, in some cases even in real time. Both of these techniques have distinct drawbacks, which include inaccuracy in areas that contain a background signal (radioactivity) or a limited degree of signal penetration (luminescence). We, and others, have reasoned that hybrid/multimodal approaches that integrate the use of these complementary modalities may help overcome their individual weaknesses. Ultimately, this will lead to advancement of the field of interventional molecular imaging/image-guided surgery. In this review, an overview of clinically applied hybrid surgical guidance technologies is given, whereby the focus is placed on tracers and hardware. PMID:26943463

Tunable terahertz wave generation through a bimodal laser diode and plasmonic photomixer.

PubMed

Yang, S-H; Watts, R; Li, X; Wang, N; Cojocaru, V; O'Gorman, J; Barry, L P; Jarrahi, M

2015-11-30

We demonstrate a compact, robust, and stable terahertz source based on a novel two section digital distributed feedback laser diode and plasmonic photomixer. Terahertz wave generation is achieved through difference frequency generation by pumping the plasmonic photomixer with two output optical beams of the two section digital distributed feedback laser diode. The laser is designed to offer an adjustable terahertz frequency difference between the emitted wavelengths by varying the applied currents to the laser sections. The plasmonic photomixer is comprised of an ultrafast photoconductor with plasmonic contact electrodes integrated with a logarithmic spiral antenna. We demonstrate terahertz wave generation with 0.15-3 THz frequency tunability, 2 MHz linewidth, and less than 5 MHz frequency stability over 1 minute, at useful power levels for practical imaging and sensing applications.

Optical mapping system with real-time control capability.

PubMed

Iravanian, Shahriar; Christini, David J

2007-10-01

Real-time, closed-loop intervention is an emerging experiment-control method that promises to provide invaluable new insight into cardiac electrophysiology. One example is the investigation of closed-loop feedback control of cardiac activity (e.g., alternans) as a possible method of preventing arrhythmia onset. To date, such methods have been investigated only in vitro using microelectrode systems, which are hindered by poor spatial resolution and are not well suited for atrial or ventricular tissue preparations. We have developed a system that uses optical mapping techniques and an electrical stimulator as the sensory and effector arms, respectively, of a closed-loop, real-time control system. The system consists of a 2,048 x 1 pixel line-scan charge-coupled device camera that records optical signals from the tissue. Custom-image processing and control software, which is implemented on top of a hard real-time operation system (RTAI Linux), process the data and make control decisions with a deterministic delay of <1 ms. The system is tested in two ways: 1) it is used to control, in real time, simulated optical signals of electrical alternans; and 2) it uses precisely timed, feedback-controlled initiation of antitachycardia pacing to terminate reentrant arrhythmias in an arterially perfused swine right ventricle stained with voltage-sensitive fluorescent dye 4{beta-[2-(di-n-butylamino)-6-napathy]vinyl}pyridinium (di-4-ANEPPS). Thus real-time control of cardiac activity using optical mapping techniques is feasible. Such a system is attractive because it offers greater measurement resolution than the electrode-based systems with which real-time control has been used previously.

Research in the Optical Sciences

DTIC Science & Technology

1990-03-12

organics for guided wave devices; nonlinear propagation and wave mixing in sodium vapor: gain/feedback approach to optical instabilities; conical... SODIUM VAPOR: GAIN/FEEDBACK APPROACH TO OPTICAL INSTABILITIES; CONICAL EMISSION; KALEIDOSCOPIC SPATIAL INSTABILITY G. Khitrova and H . M . Gibbs...Falco, "Ex situ characterization of MBE-grown molybdenum silicide thin films, The 8th Annual Symposium of the Arizona chapter of The American Vacuum

Recovering Signals from Optical Fiber Interferometric Sensors

DTIC Science & Technology

1991-06-01

GROUP SUB* GROUp Demodulation-, optical fiber, fi ber optic, sensors, passive -homodyne demodulation, symmetric demodul -ation, asymmetric demodulation...interferomeler without feedback control or modulation ofl th laser itself and without requiring the use of electronics withi -n the interferometer. One of...the 3x3 coupler permits Passive Homodyne Demodulation -of the phase-modulated signals provided by the interferometcr without feedback control or

Experimental examination of frequency locking effect in acousto-optic system

NASA Astrophysics Data System (ADS)

Mantsevich, S. N.; Balakshy, V. I.

2018-04-01

The optoelectronic system containing collinear acousto-optic cell fabricated on the base of calcium molybdate crystal and positive electronic feedback circuit was examined. The feedback signal is formed due to the optical heterodyning effect that occurs on the cell output and takes place in the special regime of collinear acousto-optic diffraction. It was discovered that three operation modes that may exist in this system. The boundaries between the modes were determined. The positions of the boundaries depend on the main parameters of the system—the incident light intensity and the feedback gain value. The new for acousto-optics phenomenon of acousto-optic system self-oscillations frequency locking by the RF generator signal was discovered and examined experimentally. Such an effect has never been observed before in the acousto-optic systems. It was experimentally shown that frequency locking effect may be used to select one of the multimode semiconductor laser longitudinal modes to improve laser radiation spectral composition.

Self-adaptive relevance feedback based on multilevel image content analysis

NASA Astrophysics Data System (ADS)

Gao, Yongying; Zhang, Yujin; Fu, Yu

2001-01-01

In current content-based image retrieval systems, it is generally accepted that obtaining high-level image features is a key to improve the querying. Among the related techniques, relevance feedback has become a hot research aspect because it combines the information from the user to refine the querying results. In practice, many methods have been proposed to achieve the goal of relevance feedback. In this paper, a new scheme for relevance feedback is proposed. Unlike previous methods for relevance feedback, our scheme provides a self-adaptive operation. First, based on multi- level image content analysis, the relevant images from the user could be automatically analyzed in different levels and the querying could be modified in terms of different analysis results. Secondly, to make it more convenient to the user, the procedure of relevance feedback could be led with memory or without memory. To test the performance of the proposed method, a practical semantic-based image retrieval system has been established, and the querying results gained by our self-adaptive relevance feedback are given.

Self-adaptive relevance feedback based on multilevel image content analysis

NASA Astrophysics Data System (ADS)

Gao, Yongying; Zhang, Yujin; Fu, Yu

2000-12-01

In current content-based image retrieval systems, it is generally accepted that obtaining high-level image features is a key to improve the querying. Among the related techniques, relevance feedback has become a hot research aspect because it combines the information from the user to refine the querying results. In practice, many methods have been proposed to achieve the goal of relevance feedback. In this paper, a new scheme for relevance feedback is proposed. Unlike previous methods for relevance feedback, our scheme provides a self-adaptive operation. First, based on multi- level image content analysis, the relevant images from the user could be automatically analyzed in different levels and the querying could be modified in terms of different analysis results. Secondly, to make it more convenient to the user, the procedure of relevance feedback could be led with memory or without memory. To test the performance of the proposed method, a practical semantic-based image retrieval system has been established, and the querying results gained by our self-adaptive relevance feedback are given.

Common-signal-induced synchronization in photonic integrated circuits and its application to secure key distribution.

PubMed

Sasaki, Takuma; Kakesu, Izumi; Mitsui, Yusuke; Rontani, Damien; Uchida, Atsushi; Sunada, Satoshi; Yoshimura, Kazuyuki; Inubushi, Masanobu

2017-10-16

We experimentally achieve common-signal-induced synchronization in two photonic integrated circuits with short external cavities driven by a constant-amplitude random-phase light. The degree of synchronization can be controlled by changing the optical feedback phase of the two photonic integrated circuits. The change in the optical feedback phase leads to a significant redistribution of the spectral energy of optical and RF spectra, which is a unique characteristic of PICs with the short external cavity. The matching of the RF and optical spectra is necessary to achieve synchronization between the two PICs, and stable synchronization can be obtained over an hour in the presence of optical feedback. We succeed in generating information-theoretic secure keys and achieving the final key generation rate of 184 kb/s using the PICs.

Cooling optically levitated dielectric nanoparticles via parametric feedback

NASA Astrophysics Data System (ADS)

Neukirch, Levi; Rodenburg, Brandon; Bhattacharya, Mishkatul; Vamivakas, Nick

2015-05-01

The inability to leverage resonant scattering processes involving internal degrees of freedom differentiates optical cooling experiments performed with levitated dielectric nanoparticles, from similar atomic and molecular traps. Trapping in optical cavities or the application of active feedback techniques have proven to be effective ways to circumvent this limitation. We present our nanoparticle optical cooling apparatus, which is based on parametric feedback modulation of a single-beam gradient force optical trap. This scheme allows us to achieve effective center-of-mass temperatures well below 1 kelvin for our ~ 1 ×10-18 kg particles, at modest vacuum pressures. The method provides a versatile platform, with parameter tunability not found in conventional tethered nanomechanical systems. Potential applications include investigations of nonequilibrium nanoscale thermodynamics, ultra-sensitive force metrology, and mesoscale quantum mechanics and hybrid systems. Supported by the office of Naval Research award number N000141410442.

Discovery Channel Telescope active optics system early integration and test

NASA Astrophysics Data System (ADS)

Venetiou, Alexander J.; Bida, Thomas A.

2012-09-01

The Discovery Channel Telescope (DCT) is a 4.3-meter telescope with a thin meniscus primary mirror (M1) and a honeycomb secondary mirror (M2). The optical design is an f/6.1 Ritchey-Chrétien (RC) with an unvignetted 0.5° Field of View (FoV) at the Cassegrain focus. We describe the design, implementation and performance of the DCT active optics system (AOS). The DCT AOS maintains collimation and controls the figure of the mirror to provide seeing-limited images across the focal plane. To minimize observing overhead, rapid settling times are achieved using a combination of feed-forward and low-bandwidth feedback control using a wavefront sensing system. In 2011, we mounted a Shack-Hartmann wavefront sensor at the prime focus of M1, the Prime Focus Test Assembly (PFTA), to test the AOS with the wavefront sensor, and the feedback loop. The incoming wavefront is decomposed using Zernike polynomials, and the mirror figure is corrected with a set of bending modes. Components of the system that we tested and tuned included the Zernike to Bending Mode transformations. We also started open-loop feed-forward coefficients determination. In early 2012, the PFTA was replaced by M2, and the wavefront sensor moved to its normal location on the Cassegrain instrument assembly. We present early open loop wavefront test results with the full optical system and instrument cube, along with refinements to the overall control loop operating at RC Cassegrain focus.

Maximum-likelihood-based extended-source spatial acquisition and tracking for planetary optical communications

NASA Astrophysics Data System (ADS)

Tsou, Haiping; Yan, Tsun-Yee

1999-04-01

This paper describes an extended-source spatial acquisition and tracking scheme for planetary optical communications. This scheme uses the Sun-lit Earth image as the beacon signal, which can be computed according to the current Sun-Earth-Probe angle from a pre-stored Earth image or a received snapshot taken by other Earth-orbiting satellite. Onboard the spacecraft, the reference image is correlated in the transform domain with the received image obtained from a detector array, which is assumed to have each of its pixels corrupted by an independent additive white Gaussian noise. The coordinate of the ground station is acquired and tracked, respectively, by an open-loop acquisition algorithm and a closed-loop tracking algorithm derived from the maximum likelihood criterion. As shown in the paper, the optimal spatial acquisition requires solving two nonlinear equations, or iteratively solving their linearized variants, to estimate the coordinate when translation in the relative positions of onboard and ground transceivers is considered. Similar assumption of linearization leads to the closed-loop spatial tracking algorithm in which the loop feedback signals can be derived from the weighted transform-domain correlation. Numerical results using a sample Sun-lit Earth image demonstrate that sub-pixel resolutions can be achieved by this scheme in a high disturbance environment.

Multimodal ophthalmic imaging using spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography

NASA Astrophysics Data System (ADS)

El-Haddad, Mohamed T.; Malone, Joseph D.; Li, Jianwei D.; Bozic, Ivan; Arquitola, Amber M.; Joos, Karen M.; Patel, Shriji N.; Tao, Yuankai K.

2017-08-01

Ophthalmic surgery involves manipulation of delicate, layered tissue structures on milli- to micrometer scales. Traditional surgical microscopes provide an inherently two-dimensional view of the surgical field with limited depth perception which precludes accurate depth-resolved visualization of these tissue layers, and limits the development of novel surgical techniques. We demonstrate multimodal swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography (SS-SESLO-OCT) to address current limitations of image-guided ophthalmic microsurgery. SS-SESLO-OCT provides inherently co-registered en face and cross-sectional field-of-views (FOVs) at a line rate of 400 kHz and >2 GPix/s throughput. We show in vivo imaging of the anterior segment and retinal fundus of a healthy volunteer, and preliminary results of multi-volumetric mosaicking for ultrawide-field retinal imaging with 90° FOV. Additionally, a scan-head was rapid-prototyped with a modular architecture which enabled integration of SS-SESLO-OCT with traditional surgical microscope and slit-lamp imaging optics. Ex vivo surgical maneuvers were simulated in cadaveric porcine eyes. The system throughput enabled volumetric acquisition at 10 volumes-per-second (vps) and allowed visualization of surgical dynamics in corneal sweeps, compressions, and dissections, and retinal sweeps, compressions, and elevations. SESLO en face images enabled simple real-time co-registration with the surgical microscope FOV, and OCT cross-sections provided depth-resolved visualization of instrument-tissue interactions. Finally, we demonstrate novel augmented-reality integration with the surgical view using segmentation overlays to aid surgical guidance. SS-SESLO-OCT may benefit clinical diagnostics by enabling aiming, registration, and mosaicking; and intraoperative imaging by allowing for real-time surgical feedback, instrument tracking, and overlays of computationally extracted biomarkers of disease.

Phase difference in modulated signals of two orthogonally polarized outputs of a Nd:YAG microchip laser with anisotropic optical feedback.

PubMed

Zhang, Peng; Tan, Yi-Dong; Liu, Ning; Wu, Yun; Zhang, Shu-Lian

2013-11-01

We present an experimental observation of the output responses of a Nd:YAG microchip laser with an anisotropic external cavity under weak optical feedback. The feedback mirror is stationary during the experiments. A pair of acousto-optic modulators is used to produce a frequency shift in the feedback light with respect to the initial light. The laser output is a beat signal with 40 kHz modulation frequency and is separated into two orthogonal directions by a Wollaston prism. Phase differences between the two intensity curves are observed as the laser works in two orthogonal modes, and vary with the external birefringence element and the pump power. Theoretical analyses are given, and the simulated results are consistent with the experimental phenomena.

Control of a Quadcopter Aerial Robot Using Optic Flow Sensing

NASA Astrophysics Data System (ADS)

Hurd, Michael Brandon

This thesis focuses on the motion control of a custom-built quadcopter aerial robot using optic flow sensing. Optic flow sensing is a vision-based approach that can provide a robot the ability to fly in global positioning system (GPS) denied environments, such as indoor environments. In this work, optic flow sensors are used to stabilize the motion of quadcopter robot, where an optic flow algorithm is applied to provide odometry measurements to the quadcopter's central processing unit to monitor the flight heading. The optic-flow sensor and algorithm are capable of gathering and processing the images at 250 frames/sec, and the sensor package weighs 2.5 g and has a footprint of 6 cm2 in area. The odometry value from the optic flow sensor is then used a feedback information in a simple proportional-integral-derivative (PID) controller on the quadcopter. Experimental results are presented to demonstrate the effectiveness of using optic flow for controlling the motion of the quadcopter aerial robot. The technique presented herein can be applied to different types of aerial robotic systems or unmanned aerial vehicles (UAVs), as well as unmanned ground vehicles (UGV).

All plastic ultra-small size imaging lens unit fabrication and evaluation for endoscope

NASA Astrophysics Data System (ADS)

Ishii, Kenta; Okamoto, Dai; Ushio, Makoto; Tai, Hidetoshi; Nishihara, Atsuhiko; Tokuda, Kimio; Kawai, Shinsuke; Kitagawa, Seiichiro

2017-02-01

There is demand for small-size lens units for endoscope and industrial applications. Polished glass lenses with a diameter of 1 - 2mm exist, however plastic lenses similar in size are not commonplace. For low-cost, light-weight, and mass production, plastic lens fabrication is extremely beneficial. Especially, in the medical field, there is strong demand for disposable lens unit for endoscopes which prevent contamination due to reuse of the lens. Therefore, high mass producible and low cost becomes increasingly important. This paper reports our findings on injection-molded ultra-small size plastic lens units with a diameter of 1.3mm and total thickness of 1.4mm. We performed optical design, injection molding, and lens unit assembly for injection moldable, high imaging performance ultra-small sized lens units. We prioritize a robust product design, considering injection molding properties and lens unit assembly, with feedback from molding simulations reflected into the optical design. A mold capable of high precision lens positioning is used to fabricate the lenses and decrease the variability of the assembly. The geometric dimensions of the resulting lenses, are measured and used in the optical simulation to validate the optical performance, and a high agreement is reported. The injection molding of the lens and the assembly of the lens unit is performed with high precision, and results in high optical performance.

Optical feedback technique extends frequency response of photoconductors

NASA Technical Reports Server (NTRS)

Katzberg, S. J.

1975-01-01

Feedback circuit consists of high-gain light-to-voltage converter with frequency-limited nonlinear photoconductor inside feedback loop. Feedback element is visible light-emitting diode with light-out versus current-in characteristic that is linear over several decades.

A mechanical mounting system for functional near-infrared spectroscopy brain imaging studies

NASA Astrophysics Data System (ADS)

Coyle, Shirley; Markham, Charles; Lanigan, William; Ward, Tomas

2005-06-01

In this work a mechanical optode mounting system for functional brain imaging with light is presented. The particular application here is a non-invasive optical brain computer interface (BCI) working in the near-infrared range. A BCI is a device that allows a user to interact with their environment through thought processes alone. Their most common use is as a communication aid for the severely disabled. We have recently pioneered the use of optical techniques for such BCI systems rather than the usual electrical modality. Our optical BCI detects characteristic changes in the cerebral haemodynamic responses that occur during motor imagery tasks. On detection of features of the optical response, resulting from localised haemodynamic changes, the BCI translates such responses and provides visual feedback to the user. While signal processing has a large part to play in terms of optimising performance we have found that it is the mechanical mounting of the optical sources and detectors (optodes) that has the greatest bearing on the performance of the system and indeed presents many interesting and novel challenges with regard to sensor placement, depth of penetration, signal intensity, artifact reduction and robustness of measurement. Here a solution is presented that accommodates the range of experimental parameters required for the application as well as meeting many of the challenges outlined above. This is the first time that a concerted study on optode mounting systems for optical BCIs has been attempted and it is hoped this paper may stimulate further research in this area.

Hand-eye calibration for rigid laparoscopes using an invariant point.

PubMed

Thompson, Stephen; Stoyanov, Danail; Schneider, Crispin; Gurusamy, Kurinchi; Ourselin, Sébastien; Davidson, Brian; Hawkes, David; Clarkson, Matthew J

2016-06-01

Laparoscopic liver resection has significant advantages over open surgery due to less patient trauma and faster recovery times, yet it can be difficult due to the restricted field of view and lack of haptic feedback. Image guidance provides a potential solution but one current challenge is in accurate "hand-eye" calibration, which determines the position and orientation of the laparoscope camera relative to the tracking markers. In this paper, we propose a simple and clinically feasible calibration method based on a single invariant point. The method requires no additional hardware, can be constructed by theatre staff during surgical setup, requires minimal image processing and can be visualised in real time. Real-time visualisation allows the surgical team to assess the calibration accuracy before use in surgery. In addition, in the laboratory, we have developed a laparoscope with an electromagnetic tracking sensor attached to the camera end and an optical tracking marker attached to the distal end. This enables a comparison of tracking performance. We have evaluated our method in the laboratory and compared it to two widely used methods, "Tsai's method" and "direct" calibration. The new method is of comparable accuracy to existing methods, and we show RMS projected error due to calibration of 1.95 mm for optical tracking and 0.85 mm for EM tracking, versus 4.13 and 1.00 mm respectively, using existing methods. The new method has also been shown to be workable under sterile conditions in the operating room. We have proposed a new method of hand-eye calibration, based on a single invariant point. Initial experience has shown that the method provides visual feedback, satisfactory accuracy and can be performed during surgery. We also show that an EM sensor placed near the camera would provide significantly improved image overlay accuracy.

Through-wafer interrogation of microstructure motion for MEMS feedback control

NASA Astrophysics Data System (ADS)

Dawson, Jeremy M.; Chen, Jingdong; Brown, Kolin S.; Famouri, Parviz F.; Hornak, Lawrence A.

1999-09-01

Closed-loop MEMS control enables mechanical microsystems to adapt to the demands of the environment which they are actuating opening a new window of opportunity for future MEMS applications. Planar diffractive optical microsystems have the potential to enable the integrated optical interrogation of MEMS microstructure position fully decoupled from the means of mechanical actuation which is central to realization of feedback control. This paper presents the results of initial research evaluating through-wafer optical microsystems for MEMS integrated optical monitoring. Positional monitoring results obtained from a 1.3 micrometer wavelength through- wafer free-space optical probe of a lateral comb resonator fabricated using the Multi-User MEMS Process Service (MUMPS) are presented. Given the availability of positional information via probe signal feedback, a simulation of the application of nonlinear sliding control is presented illustrating position control of the lateral comb resonator structure.

Multistate intermittency on the route to chaos of a semiconductor laser subjected to optical feedback from a long external cavity.

PubMed

Choi, Daeyoung; Wishon, Michael J; Chang, C Y; Citrin, D S; Locquet, A

2018-01-01

We observe experimentally two regimes of intermittency on the route to chaos of a semiconductor laser subjected to optical feedback from a long external cavity as the feedback level is increased. The first regime encountered corresponds to multistate intermittency involving two or three states composed of several combinations of periodic, quasiperiodic, and subharmonic dynamics. The second regime is observed for larger feedback levels and involves intermittency between period-doubled and chaotic regimes. This latter type of intermittency displays statistical properties similar to those of on-off intermittency.

Emergence of resonant mode-locking via delayed feedback in quantum dot semiconductor lasers.

PubMed

Tykalewicz, B; Goulding, D; Hegarty, S P; Huyet, G; Erneux, T; Kelleher, B; Viktorov, E A

2016-02-22

With conventional semiconductor lasers undergoing external optical feedback, a chaotic output is typically observed even for moderate levels of the feedback strength. In this paper we examine single mode quantum dot lasers under strong optical feedback conditions and show that an entirely new dynamical regime is found consisting of spontaneous mode-locking via a resonance between the relaxation oscillation frequency and the external cavity repetition rate. Experimental observations are supported by detailed numerical simulations of rate equations appropriate for this laser type. The phenomenon constitutes an entirely new mode-locking mechanism in semiconductor lasers.

Ultralow-dose, feedback imaging with laser-Compton X-ray and laser-Compton gamma ray sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barty, Christopher P. J.

Ultralow-dose, x-ray or gamma-ray imaging is based on fast, electronic control of the output of a laser-Compton x-ray or gamma-ray source (LCXS or LCGS). X-ray or gamma-ray shadowgraphs are constructed one (or a few) pixel(s) at a time by monitoring the LCXS or LCGS beam energy required at each pixel of the object to achieve a threshold level of detectability at the detector. An example provides that once the threshold for detection is reached, an electronic or optical signal is sent to the LCXS/LCGS that enables a fast optical switch that diverts, either in space or time the laser pulsesmore » used to create Compton photons. In this way, one prevents the object from being exposed to any further Compton x-rays or gamma-rays until either the laser-Compton beam or the object are moved so that a new pixel location may be illumination.« less

Opto-acoustic thrombolysis

DOEpatents

Celliers, Peter; Da Silva, Luiz; Glinsky, Michael; London, Richard; Maitland, Duncan; Matthews, Dennis; Fitch, Pat

2000-01-01

This invention is a catheter-based device for generating an ultrasound excitation in biological tissue. Pulsed laser light is guided through an optical fiber to provide the energy for producing the acoustic vibrations. The optical energy is deposited in a water-based absorbing fluid, e.g. saline, thrombolytic agent, blood or thrombus, and generates an acoustic impulse in the fluid through thermoelastic and/or thermodynamic mechanisms. By pulsing the laser at a repetition rate (which may vary from 10 Hz to 100 kHz) an ultrasonic radiation field can be established locally in the medium. This method of producing ultrasonic vibrations can be used in vivo for the treatment of stroke-related conditions in humans, particularly for dissolving thrombus or treating vasospasm. The catheter can also incorporate thrombolytic drug treatments as an adjunct therapy and it can be operated in conjunction with ultrasonic detection equipment for imaging and feedback control and with optical sensors for characterization of thrombus type and consistency.

Automatic medical image annotation and keyword-based image retrieval using relevance feedback.

PubMed

Ko, Byoung Chul; Lee, JiHyeon; Nam, Jae-Yeal

2012-08-01

This paper presents novel multiple keywords annotation for medical images, keyword-based medical image retrieval, and relevance feedback method for image retrieval for enhancing image retrieval performance. For semantic keyword annotation, this study proposes a novel medical image classification method combining local wavelet-based center symmetric-local binary patterns with random forests. For keyword-based image retrieval, our retrieval system use the confidence score that is assigned to each annotated keyword by combining probabilities of random forests with predefined body relation graph. To overcome the limitation of keyword-based image retrieval, we combine our image retrieval system with relevance feedback mechanism based on visual feature and pattern classifier. Compared with other annotation and relevance feedback algorithms, the proposed method shows both improved annotation performance and accurate retrieval results.

High-power fused assemblies enabled by advances in fiber-processing technologies

NASA Astrophysics Data System (ADS)

Wiley, Robert; Clark, Brett

2011-02-01

The power handling capabilities of fiber lasers are limited by the technologies available to fabricate and assemble the key optical system components. Previous tools for the assembly, tapering, and fusion of fiber laser elements have had drawbacks with regard to temperature range, alignment capability, assembly flexibility and surface contamination. To provide expanded capabilities for fiber laser assembly, a wide-area electrical plasma heat source was used in conjunction with an optimized image analysis method and a flexible alignment system, integrated according to mechatronic principles. High-resolution imaging and vision-based measurement provided feedback to adjust assembly, fusion, and tapering process parameters. The system was used to perform assembly steps including dissimilar-fiber splicing, tapering, bundling, capillary bundling, and fusion of fibers to bulk optic devices up to several mm in diameter. A wide range of fiber types and diameters were tested, including extremely large diameters and photonic crystal fibers. The assemblies were evaluated for conformation to optical and mechanical design criteria, such as taper geometry and splice loss. The completed assemblies met the performance targets and exhibited reduced surface contamination compared to assemblies prepared on previously existing equipment. The imaging system and image analysis algorithms provided in situ fiber geometry measurement data that agreed well with external measurement. The ability to adjust operating parameters dynamically based on imaging was shown to provide substantial performance benefits, particularly in the tapering of fibers and bundles. The integrated design approach was shown to provide sufficient flexibility to perform all required operations with a minimum of reconfiguration.

Strong suppression of shot noise in a feedback-controlled single-electron transistor

NASA Astrophysics Data System (ADS)

Wagner, Timo; Strasberg, Philipp; Bayer, Johannes C.; Rugeramigabo, Eddy P.; Brandes, Tobias; Haug, Rolf J.

2017-03-01

Feedback control of quantum mechanical systems is rapidly attracting attention not only due to fundamental questions about quantum measurements, but also because of its novel applications in many fields in physics. Quantum control has been studied intensively in quantum optics but progress has recently been made in the control of solid-state qubits as well. In quantum transport only a few active and passive feedback experiments have been realized on the level of single electrons, although theoretical proposals exist. Here we demonstrate the suppression of shot noise in a single-electron transistor using an exclusively electronic closed-loop feedback to monitor and adjust the counting statistics. With increasing feedback response we observe a stronger suppression and faster freezing of charge current fluctuations. Our technique is analogous to the generation of squeezed light with in-loop photodetection as used in quantum optics. Sub-Poisson single-electron sources will pave the way for high-precision measurements in quantum transport similar to optical or optomechanical equivalents.

Measurements of the linewidth enhancement factor of mid-infrared quantum cascade lasers by different optical feedback techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jumpertz, L., E-mail: louise.jumpertz@telecom-paristech.fr; MirSense, 8 avenue de la Vauve, F-91120 Palaiseau; Michel, F.

2016-01-15

Precise knowledge of the linewidth enhancement factor of a semiconductor laser under actual operating conditions is of prime importance since this parameter dictates various phenomena such as linewidth broadening or optical nonlinearities enhancement. The above-threshold linewidth enhancement factor of a mid-infrared quantum cascade laser structure operated at 10{sup ∘}C is determined experimentally using two different methods based on optical feedback. Both Fabry-Perot and distributed feedback quantum cascade lasers based on the same active area design are studied, the former by following the wavelength shift as a function of the feedback strength and the latter by self-mixing interferometry. The results aremore » consistent and unveil a clear pump current dependence of the linewidth enhancement factor, with values ranging from 0.8 to about 3.« less

Two-dimensional dissipative rogue waves due to time-delayed feedback in cavity nonlinear optics.

PubMed

Tlidi, Mustapha; Panajotov, Krassimir

2017-01-01

We demonstrate a way to generate two-dimensional rogue waves in two types of broad area nonlinear optical systems subject to time-delayed feedback: in the generic Lugiato-Lefever model and in the model of a broad-area surface-emitting laser with saturable absorber. The delayed feedback is found to induce a spontaneous formation of rogue waves. In the absence of delayed feedback, spatial pulses are stationary. The rogue waves are exited and controlled by the delay feedback. We characterize their formation by computing the probability distribution of the pulse height. The long-tailed statistical contribution, which is often considered as a signature of the presence of rogue waves, appears for sufficiently strong feedback. The generality of our analysis suggests that the feedback induced instability leading to the spontaneous formation of two-dimensional rogue waves is a universal phenomenon.

Technique development for photoacoustic imaging guided interventions

NASA Astrophysics Data System (ADS)

Cheng, Qian; Zhang, Haonan; Yuan, Jie; Feng, Ting; Xu, Guan; Wang, Xueding

2015-03-01

Laser-induced thermotherapy (LITT), i.e. tissue destruction induced by a local increase of temperature by means of laser light energy transmission, has been frequently used for minimally invasive treatments of various diseases such as benign thyroid nodules and liver cancer. The emerging photoacoustic (PA) imaging, when integrated with ultrasound (US), could contribute to LITT procedure. PA can enable a good visualization of percutaneous apparatus deep inside tissue and, therefore, can offer accurate guidance of the optical fibers to the target tissue. Our initial experiment demonstrated that, by picking the strong photoacoustic signals generated at the tips of optical fibers as a needle, the trajectory and position of the fibers could be visualized clearly using a commercial available US unit. When working the conventional US Bscan mode, the fibers disappeared when the angle between the fibers and the probe surface was larger than 60 degree; while working on the new PA mode, the fibers could be visualized without any problem even when the angle between the fibers and the probe surface was larger than 75 degree. Moreover, with PA imaging function integrated, the optical fibers positioned into the target tissue, besides delivering optical energy for thermotherapy, can also be used to generate PA signals for on-line evaluation of LITT. Powered by our recently developed PA physio-chemical analysis, PA measurements from the tissue can provide a direct and accurate feedback of the tissue responses to laser ablation, including the changes in not only chemical compositions but also histological microstructures. The initial experiment on the rat liver model has demonstrated the excellent sensitivity of PA imaging to the changes in tissue temperature rise and tissue status (from native to coagulated) when the tissue is treated in vivo with LITT.

CHEERS Results from NGC 3393. II. Investigating the Extended Narrow-line Region Using Deep Chandra Observations and Hubble Space Telescope Narrow-line Imaging

NASA Astrophysics Data System (ADS)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Paggi, Alessandro; Raymond, John; Wang, Junfeng; Storchi-Bergmann, Thaisa

2017-07-01

The CHandra Extended Emission Line Region Survey (CHEERS) is an X-ray study of nearby active galactic nuclei (AGNs) designed to take full advantage of Chandra's unique angular resolution by spatially resolving feedback signatures and effects. In the second paper of a series on CHEERS target NGC 3393, we examine deep high-resolution Chandra images and compare them with Hubble Space Telescope narrow-line images of [O III], [S II], and Hα, as well as previously unpublished mid-ultraviolet (MUV) images. The X-rays provide unprecedented evidence that the S-shaped arms that envelope the nuclear radio outflows extend only ≲0.″2 (≲50 pc) across. The high-resolution multiwavelength data suggest that the extended narrow-line region is a complex multiphase structure in the circumnuclear interstellar medium (ISM). Its ionization structure is highly stratified with respect to outflow-driven bubbles in the bicone and varies dramatically on scales of ˜10 pc. Multiple findings show likely contributions from shocks to the feedback in regions where radio outflows from the AGN most directly influence the ISM. These findings include Hα evidence for gas compression and extended MUV emission and are in agreement with existing STIS kinematics. Extended filamentary structure in the X-rays and optical suggests the presence of an undetected plasma component, whose existence could be tested with deeper radio observations.

Design of freeform optics for an ophthalmological application

NASA Astrophysics Data System (ADS)

Sieber, Ingo; Yi, Allen; Li, Likai; Beckert, Erik; Steinkopf, Ralf; Gengenbach, Ulrich

2014-05-01

Optical freeform surfaces are gaining importance in different optical applications. A huge demand arises e.g. in the fields of automotive and medical engineering. Innovative systems often need high-quality and high-volume optics. Injectionmoulded polymer optics represents a cost-efficient solution. However, it has to be ensured that the tight requirements with respect to the system's performance are met by the replicated freeform optics. To reach this goal, it is not sufficient to only characterise the manufactured optics by peak-to-valley or rms data describing a deviation from the nominal surface. Instead, optical performance of the manufactured freeform optics has to be analysed and compared with the performance of the nominal surface. This can be done by integrating the measured surface data of the manufactured freeform optics into the optical simulation model. The feedback of the measured surface data into the model allows for a simulation of the optical performance of the optical subsystem containing the real freeform optics manufactured. Hence, conclusions can be drawn as to whether the specifications with respect to e.g. imaging quality are met by the real manufactured optics. This approach will be presented using an Alvarez-Humphrey optics as an example of a tuneable optics of an ophthalmological application. The focus of this article will be on design for manufacturing the freeform optics, the integration of the measured surface data into the optical simulation model, simulation of the optical performance, and analysis in comparison to the nominal surface.

Real-time optical coherence tomography observation of retinal tissue damage during laser photocoagulation therapy on ex-vivo porcine samples

NASA Astrophysics Data System (ADS)

Steiner, P.; Považay, B.; Stoller, M.; Morgenthaler, P.; Inniger, D.; Arnold, P.; Sznitman, R.; Meier, Ch.

2015-07-01

Retinal laser photocoagulation represents a widely used treatment for retinal pathologies such as diabetic chorioretinopathy or diabetic edema. For effective treatment, an appropriate choice of the treatment energy dose is crucial to prevent excessive tissue damage caused by over-irradiation of the retina. In this manuscript we investigate simultaneous and time-resolved optical coherence tomography for its applicability to provide feedback to the ophthalmologist about the introduced retinal damage during laser photocoagulation. Time-resolved and volumetric optical coherence tomography data of 96 lesions on ex-vivo porcine samples, set with a 577 nm laser prototype and irradiance of between 300 and 8800 W=cm2 were analyzed. Time-resolved scans were compared to volumetric scans of the lesion and correlated with ophthalmoscopic visibility. Lastly, image parameters extracted from optical coherence tomography Mscans, suitable for lesion classification were identified. Results presented in this work support the hypothesis that simultaneous optical coherence tomography provides valuable information about the extent of retinal tissue damage and may be used to guide retinal laser photocoagulation in the future.

Drifting cavity solitons and dissipative rogue waves induced by time-delayed feedback in Kerr optical frequency comb and in all fiber cavities

NASA Astrophysics Data System (ADS)

Tlidi, Mustapha; Panajotov, Krassimir; Ferré, Michel; Clerc, Marcel G.

2017-11-01

Time-delayed feedback plays an important role in the dynamics of spatially extended systems. In this contribution, we consider the generic Lugiato-Lefever model with delay feedback that describes Kerr optical frequency comb in all fiber cavities. We show that the delay feedback strongly impacts the spatiotemporal dynamical behavior resulting from modulational instability by (i) reducing the threshold associated with modulational instability and by (ii) decreasing the critical frequency at the onset of this instability. We show that for moderate input intensities it is possible to generate drifting cavity solitons with an asymmetric radiation emitted from the soliton tails. Finally, we characterize the formation of rogue waves induced by the delay feedback.

Fabrication and test of digital output interface devices for gas turbine electronic controls

NASA Technical Reports Server (NTRS)

Newirth, D. M.; Koenig, E. W.

1978-01-01

A program was conducted to develop an innovative digital output interface device, a digital effector with optical feedback of the fuel metering valve position, for future electronic controls for gas turbine engines. A digital effector (on-off solenoids driven directly by on-off signals from a digital electronic controller) with optical position feedback was fabricated, coupled with the fuel metering valve, and tested under simulated engine operating conditions. The testing indicated that a digital effector with optical position feedback is a suitable candidate, with proper development for future digital electronic gas turbine controls. The testing also identified several problem areas which would have to be overcome in a final production configuration.

Single-mode, narrow-linewidth external cavity quantum cascade laser through optical feedback from a partial-reflector.

PubMed

Cendejas, Richard A; Phillips, Mark C; Myers, Tanya L; Taubman, Matthew S

2010-12-06

An external-cavity (EC) quantum cascade (QC) laser using optical feedback from a partial-reflector is reported. With this configuration, the otherwise multi-mode emission of a Fabry-Perot QC laser was made single-mode with optical output powers exceeding 40 mW. A mode-hop free tuning range of 2.46 cm(-1) was achieved by synchronously tuning the EC length and QC laser current. The linewidth of the partial-reflector EC-QC laser was measured for integration times from 100 μs to 4 seconds, and compared to a distributed feedback QC laser. Linewidths as small as 480 kHz were recorded for the EC-QC laser.

Optical coherence tomography-guided laser microsurgery for blood coagulation with continuous-wave laser diode.

PubMed

Chang, Feng-Yu; Tsai, Meng-Tsan; Wang, Zu-Yi; Chi, Chun-Kai; Lee, Cheng-Kuang; Yang, Chih-Hsun; Chan, Ming-Che; Lee, Ya-Ju

2015-11-16

Blood coagulation is the clotting and subsequent dissolution of the clot following repair to the damaged tissue. However, inducing blood coagulation is difficult for some patients with homeostasis dysfunction or during surgery. In this study, we proposed a method to develop an integrated system that combines optical coherence tomography (OCT) and laser microsurgery for blood coagulation. Also, an algorithm for positioning of the treatment location from OCT images was developed. With OCT scanning, 2D/3D OCT images and angiography of tissue can be obtained simultaneously, enabling to noninvasively reconstruct the morphological and microvascular structures for real-time monitoring of changes in biological tissues during laser microsurgery. Instead of high-cost pulsed lasers, continuous-wave laser diodes (CW-LDs) with the central wavelengths of 450 nm and 532 nm are used for blood coagulation, corresponding to higher absorption coefficients of oxyhemoglobin and deoxyhemoglobin. Experimental results showed that the location of laser exposure can be accurately controlled with the proposed approach of imaging-based feedback positioning. Moreover, blood coagulation can be efficiently induced by CW-LDs and the coagulation process can be monitored in real-time with OCT. This technology enables to potentially provide accurate positioning for laser microsurgery and control the laser exposure to avoid extra damage by real-time OCT imaging.

Optical coherence tomography-guided laser microsurgery for blood coagulation with continuous-wave laser diode

NASA Astrophysics Data System (ADS)

Chang, Feng-Yu; Tsai, Meng-Tsan; Wang, Zu-Yi; Chi, Chun-Kai; Lee, Cheng-Kuang; Yang, Chih-Hsun; Chan, Ming-Che; Lee, Ya-Ju

2015-11-01

Blood coagulation is the clotting and subsequent dissolution of the clot following repair to the damaged tissue. However, inducing blood coagulation is difficult for some patients with homeostasis dysfunction or during surgery. In this study, we proposed a method to develop an integrated system that combines optical coherence tomography (OCT) and laser microsurgery for blood coagulation. Also, an algorithm for positioning of the treatment location from OCT images was developed. With OCT scanning, 2D/3D OCT images and angiography of tissue can be obtained simultaneously, enabling to noninvasively reconstruct the morphological and microvascular structures for real-time monitoring of changes in biological tissues during laser microsurgery. Instead of high-cost pulsed lasers, continuous-wave laser diodes (CW-LDs) with the central wavelengths of 450 nm and 532 nm are used for blood coagulation, corresponding to higher absorption coefficients of oxyhemoglobin and deoxyhemoglobin. Experimental results showed that the location of laser exposure can be accurately controlled with the proposed approach of imaging-based feedback positioning. Moreover, blood coagulation can be efficiently induced by CW-LDs and the coagulation process can be monitored in real-time with OCT. This technology enables to potentially provide accurate positioning for laser microsurgery and control the laser exposure to avoid extra damage by real-time OCT imaging.

Chaos synchronization in vertical-cavity surface-emitting laser based on rotated polarization-preserved optical feedback.

PubMed

Nazhan, Salam; Ghassemlooy, Zabih; Busawon, Krishna

2016-01-01

In this paper, the influence of the rotating polarization-preserved optical feedback on the chaos synchronization of a vertical-cavity surface-emitting laser (VCSEL) is investigated experimentally. Two VCSELs' polarization modes (XP) and (YP) are gradually rotated and re-injected back into the VCSEL. The anti-phase dynamics synchronization of the two polarization modes is evaluated using the cross-correlation function. For a fixed optical feedback, a clear relationship is found between the cross-correlation coefficient and the polarization angle θp. It is shown that high-quality anti-phase polarization-resolved chaos synchronization is achieved at higher values of θp. The maximum value of the cross-correlation coefficient achieved is -0.99 with a zero time delay over a wide range of θp beyond 65° with a poor synchronization dynamic at θp less than 65°. Furthermore, it is observed that the antiphase irregular oscillation of the XP and YP modes changes with θp. VCSEL under the rotating polarization optical feedback can be a good candidate as a chaotic synchronization source for a secure communication system.

A sensor-type application of a self-oscillating dynamic system with a fiber optic feedback line, including chemical sensors and biosensors

NASA Astrophysics Data System (ADS)

Rabinovich, Emmanuel M.

2004-05-01

We present an overview of research, conducted and published by the author and colleagues during the preceding decade, with self-oscillating dynamic systems. Special attention has been addressed to sensor type applications that allow one to design a new type of sensors of different physical parameters as well as using system for chemical and biosensors. Many detection methods exploit self-oscillating systems, such as lasers and RF or microwave oscillators, and use changes introduced into a feedback mechanism (for instance laser inter-cavity spectroscopy) for evaluation of different physical parameters such as refractive indices or absorption coefficients. Typically, that approach is very efficient, is easy to implement, and gives high sensitivity. We have demonstrated that a similar method can be used in the case of an RF optoelectronic self-oscillating system (OSOS) with a fiber-optic feedback line. Using fiber as an element of a positive feedback line allows one to design a new family of fiber-optic sensors each of which can be integrated into a fiber-optic feedback line. Changes introduced into the feedback line of an OSOS typically cause an RF frequency shift that can be measured very precisely with an RF frequency counter or spectrum analyzer. For some types of sensors an OSOS can easily incorporate and utilize advantages of well-developed modern inexpensive light sources (VCSELs, LEDs) and opto-electronic components that have been designed for communication purposes. A single closed loop OSOS can be easily duplicated for sensor array measurement via the use of parallel fiber-optics (for example VCSEL arrays and fiber ribbon cables) that have been well developed for telecommunication systems.

Providing haptic feedback in robot-assisted minimally invasive surgery: a direct optical force-sensing solution for haptic rendering of deformable bodies.

PubMed

Ehrampoosh, Shervin; Dave, Mohit; Kia, Michael A; Rablau, Corneliu; Zadeh, Mehrdad H

2013-01-01

This paper presents an enhanced haptic-enabled master-slave teleoperation system which can be used to provide force feedback to surgeons in minimally invasive surgery (MIS). One of the research goals was to develop a combined-control architecture framework that included both direct force reflection (DFR) and position-error-based (PEB) control strategies. To achieve this goal, it was essential to measure accurately the direct contact forces between deformable bodies and a robotic tool tip. To measure the forces at a surgical tool tip and enhance the performance of the teleoperation system, an optical force sensor was designed, prototyped, and added to a robot manipulator. The enhanced teleoperation architecture was formulated by developing mathematical models for the optical force sensor, the extended slave robot manipulator, and the combined-control strategy. Human factor studies were also conducted to (a) examine experimentally the performance of the enhanced teleoperation system with the optical force sensor, and (b) study human haptic perception during the identification of remote object deformability. The first experiment was carried out to discriminate deformability of objects when human subjects were in direct contact with deformable objects by means of a laparoscopic tool. The control parameters were then tuned based on the results of this experiment using a gain-scheduling method. The second experiment was conducted to study the effectiveness of the force feedback provided through the enhanced teleoperation system. The results show that the force feedback increased the ability of subjects to correctly identify materials of different deformable types. In addition, the virtual force feedback provided by the teleoperation system comes close to the real force feedback experienced in direct MIS. The experimental results provide design guidelines for choosing and validating the control architecture and the optical force sensor.

Motion video compression system with neural network having winner-take-all function

NASA Technical Reports Server (NTRS)

Fang, Wai-Chi (Inventor); Sheu, Bing J. (Inventor)

1997-01-01

A motion video data system includes a compression system, including an image compressor, an image decompressor correlative to the image compressor having an input connected to an output of the image compressor, a feedback summing node having one input connected to an output of the image decompressor, a picture memory having an input connected to an output of the feedback summing node, apparatus for comparing an image stored in the picture memory with a received input image and deducing therefrom pixels having differences between the stored image and the received image and for retrieving from the picture memory a partial image including the pixels only and applying the partial image to another input of the feedback summing node, whereby to produce at the output of the feedback summing node an updated decompressed image, a subtraction node having one input connected to received the received image and another input connected to receive the partial image so as to generate a difference image, the image compressor having an input connected to receive the difference image whereby to produce a compressed difference image at the output of the image compressor.

Integrated-optic current sensors with a multimode interference waveguide device.

PubMed

Kim, Sung-Moon; Chu, Woo-Sung; Kim, Sang-Guk; Oh, Min-Cheol

2016-04-04

Optical current sensors based on polarization-rotated reflection interferometry are demonstrated using polymeric integrated optics and various functional optical waveguide devices. Interferometric sensors normally require bias feedback control for maintaining the operating point, which increases the cost. In order to resolve this constraint of feedback control, a multimode interference (MMI) waveguide device is integrated onto the current-sensor optical chip in this work. From the multiple outputs of the MMI, a 90° phase-shifted transfer function is obtained. Using passive quadrature demodulation, we demonstrate that the sensor could maintain the output signal regardless of the drift in the operating bias-point.

A Spatially Resolved Investigation on the Influence of AGN and Star Formation in a Lensed Main-Sequence Galaxy at z = 2.39

NASA Astrophysics Data System (ADS)

Fischer, Travis; Rigby, Jane; Gladders, Michael; Sharon, Keren q.; Barrientos, L. Felipe; Bayliss, Matt; Dahle, Håkon; Florian, Michael; Johnson, Traci Lin; Wuyts, Eva

2018-01-01

We present rest-frame optical SINFONI integral field spectroscopy and rest-frame UV HST imaging of a lensed galaxy hosting an active galactic nucleus (AGN) at z = 2.39. Galactic wind feedback is widely acknowledged to play a critical role in the evolution of galaxies, however, the physical mechanisms involved and the relative importance of AGN and star formation as the main feedback drivers remain poorly understood. AGN-driven feedback has been evident in very luminous but rare quasars and radio galaxies, but observational evidence remains lacking for less extreme, “normal” star-forming galaxies. We report, for the first time at high redshift, spatially resolved velocity profiles and geometries of an AGN-driven outflow in a normal star-forming galaxy and spatial extents and morphologies of Lyα emission and stellar UV continuum. Analyzing these measurements in tandem, we determine the physical conditions, geometry, and excitation sources of the interstellar medium in a star-forming, AGN-hosting galaxy at cosmic noon.

Remote assessment of diabetic foot ulcers using a novel wound imaging system.

PubMed

Bowling, Frank L; King, Laurie; Paterson, James A; Hu, Jingyi; Lipsky, Benjamin A; Matthews, David R; Boulton, Andrew J M

2011-01-01

Telemedicine allows experts to assess patients in remote locations, enabling quality convenient, cost-effective care. To help assess foot wounds remotely, we investigated the reliability of a novel optical imaging system employing a three-dimensional camera and disposable optical marker. We first examined inter- and intraoperator measurement variability (correlation coefficient) of five clinicians examining three different wounds. Then, to assess of the system's ability to identify key clinically relevant features, we had two clinicians evaluate 20 different wounds at two centers, recording observations on a standardized form. Three other clinicians recorded their observations using only the corresponding three-dimensional images. Using the in-person assessment as the criterion standard, we assessed concordance of the remote with in-person assessments. Measurement variation of area was 3.3% for intraoperator and 11.9% for interoperator; difference in clinician opinion about wound boundary location was significant. Overall agreement for remote vs. in-person assessments was good, but was lowest on the subjective clinical assessments, e.g., value of debridement to improve healing. Limitations of imaging included inability to show certain characteristics, e.g., moistness or exudation. Clinicians gave positive feedback on visual fidelity. This pilot study showed that a clinician viewing only the three-dimensional images could accurately measure and assess a diabetic foot wound remotely. © 2010 by the Wound Healing Society.

Live volumetric (4D) visualization and guidance of in vivo human ophthalmic surgery with intraoperative optical coherence tomography

PubMed Central

Carrasco-Zevallos, O. M.; Keller, B.; Viehland, C.; Shen, L.; Waterman, G.; Todorich, B.; Shieh, C.; Hahn, P.; Farsiu, S.; Kuo, A. N.; Toth, C. A.; Izatt, J. A.

2016-01-01

Minimally-invasive microsurgery has resulted in improved outcomes for patients. However, operating through a microscope limits depth perception and fixes the visual perspective, which result in a steep learning curve to achieve microsurgical proficiency. We introduce a surgical imaging system employing four-dimensional (live volumetric imaging through time) microscope-integrated optical coherence tomography (4D MIOCT) capable of imaging at up to 10 volumes per second to visualize human microsurgery. A custom stereoscopic heads-up display provides real-time interactive volumetric feedback to the surgeon. We report that 4D MIOCT enhanced suturing accuracy and control of instrument positioning in mock surgical trials involving 17 ophthalmic surgeons. Additionally, 4D MIOCT imaging was performed in 48 human eye surgeries and was demonstrated to successfully visualize the pathology of interest in concordance with preoperative diagnosis in 93% of retinal surgeries and the surgical site of interest in 100% of anterior segment surgeries. In vivo 4D MIOCT imaging revealed sub-surface pathologic structures and instrument-induced lesions that were invisible through the operating microscope during standard surgical maneuvers. In select cases, 4D MIOCT guidance was necessary to resolve such lesions and prevent post-operative complications. Our novel surgical visualization platform achieves surgeon-interactive 4D visualization of live surgery which could expand the surgeon’s capabilities. PMID:27538478

Live volumetric (4D) visualization and guidance of in vivo human ophthalmic surgery with intraoperative optical coherence tomography

NASA Astrophysics Data System (ADS)

Carrasco-Zevallos, O. M.; Keller, B.; Viehland, C.; Shen, L.; Waterman, G.; Todorich, B.; Shieh, C.; Hahn, P.; Farsiu, S.; Kuo, A. N.; Toth, C. A.; Izatt, J. A.

2016-08-01

Minimally-invasive microsurgery has resulted in improved outcomes for patients. However, operating through a microscope limits depth perception and fixes the visual perspective, which result in a steep learning curve to achieve microsurgical proficiency. We introduce a surgical imaging system employing four-dimensional (live volumetric imaging through time) microscope-integrated optical coherence tomography (4D MIOCT) capable of imaging at up to 10 volumes per second to visualize human microsurgery. A custom stereoscopic heads-up display provides real-time interactive volumetric feedback to the surgeon. We report that 4D MIOCT enhanced suturing accuracy and control of instrument positioning in mock surgical trials involving 17 ophthalmic surgeons. Additionally, 4D MIOCT imaging was performed in 48 human eye surgeries and was demonstrated to successfully visualize the pathology of interest in concordance with preoperative diagnosis in 93% of retinal surgeries and the surgical site of interest in 100% of anterior segment surgeries. In vivo 4D MIOCT imaging revealed sub-surface pathologic structures and instrument-induced lesions that were invisible through the operating microscope during standard surgical maneuvers. In select cases, 4D MIOCT guidance was necessary to resolve such lesions and prevent post-operative complications. Our novel surgical visualization platform achieves surgeon-interactive 4D visualization of live surgery which could expand the surgeon’s capabilities.

Two-dimensional tracking of a motile micro-organism allowing high-resolution observation with various imaging techniques

NASA Astrophysics Data System (ADS)

Oku, H.; Ogawa, N.; Ishikawa, M.; Hashimoto, K.

2005-03-01

In this article, a micro-organism tracking system using a high-speed vision system is reported. This system two dimensionally tracks a freely swimming micro-organism within the field of an optical microscope by moving a chamber of target micro-organisms based on high-speed visual feedback. The system we developed could track a paramecium using various imaging techniques, including bright-field illumination, dark-field illumination, and differential interference contrast, at magnifications of 5 times and 20 times. A maximum tracking duration of 300s was demonstrated. Also, the system could track an object with a velocity of up to 35 000μm/s (175diameters/s), which is significantly faster than swimming micro-organisms.

CFO compensation method using optical feedback path for coherent optical OFDM system

NASA Astrophysics Data System (ADS)

Moon, Sang-Rok; Hwang, In-Ki; Kang, Hun-Sik; Chang, Sun Hyok; Lee, Seung-Woo; Lee, Joon Ki

2017-07-01

We investigate feasibility of carrier frequency offset (CFO) compensation method using optical feedback path for coherent optical orthogonal frequency division multiplexing (CO-OFDM) system. Recently proposed CFO compensation algorithms provide wide CFO estimation range in electrical domain. However, their practical compensation range is limited by sampling rate of an analog-to-digital converter (ADC). This limitation has not drawn attention, since the ADC sampling rate was high enough comparing to the data bandwidth and CFO in the wireless OFDM system. For CO-OFDM, the limitation is becoming visible because of increased data bandwidth, laser instability (i.e. large CFO) and insufficient ADC sampling rate owing to high cost. To solve the problem and extend practical CFO compensation range, we propose a CFO compensation method having optical feedback path. By adding simple wavelength control for local oscillator, the practical CFO compensation range can be extended to the sampling frequency range. The feasibility of the proposed method is experimentally investigated.

Noninvasive laser vasectomy

NASA Astrophysics Data System (ADS)

Cilip, Christopher Michael

Development of a noninvasive vasectomy technique may eliminate male fear of complications (incision, bleeding, infection, and scrotal pain) and result in a more popular procedure. These studies build off previous studies that report the ability to thermally target tissue substructures with near infrared laser radiation while maintaining a healthy superficial layer of tissue through active surface cooling. Initial studies showed the ability to increase the working depth compared to that of common dermatological procedures and the translation into an ex vivo canine model targeting the vas deferens in a noninvasive laser vasectomy. Laser and cooling parameter optimization was required to determine the best possible wavelength for a safe transition to an in vivo canine model. Optical clearing agents were investigated as a mechanism to decrease tissue scattering during in vivo procedures to increase optical penetration depth and reduce the overall power required. Optical and thermal computer models were developed to determine the efficacy for a successful transition into a human model. Common clinical imaging modalities (ultrasound, high frequency ultrasound, and optical coherence tomography) were tested as possible candidates for real-time imaging feedback to determine surgical success. Finally, a noninvasive laser vasectomy prototype clamp incorporating laser, cooling, and control in a single package was designed and tested in vivo. Occlusion of the canine vas deferens able to withstand physiological burst pressures measured postoperative was shown during acute and chronic studies. This procedure is ready for azoospermia and recanalization studies in a clinical setting.

The effect of providing feedback on the characteristics of student responses to a videotaped format for high school physics assessment

NASA Astrophysics Data System (ADS)

Lawrence, Michael John

1997-12-01

The problem of science illiteracy has been well documented. The development of the critical thinking skills in science education are often sacrificed in favor of content coverage. Opportunities for critical thinking within a context of science have been recommended to promote science literacy (AAAS, 1993). One means of doing this is to have students make and explain predictions involving physical phenomena, observe feedback, and then revise the prediction. A videotaped assessment using this process served as the focus for this study. High school physics students were asked to predict and explain what would happen in situations involving optics. They were then given different feedback treatments. The purpose of this study was to: (a) examine the effect of providing feedback on the quality of responses in making both revisions and subsequent predictions, and (b) examine the relationship between content knowledge and qualitative performance. Sixty-four high ability students were separated into three treatment groups: no feedback (NF), visual feedback (F), and teacher-explained feedback (TE). These students responded to six items on the Optics Videotape Assessment and ten optics multiple choice items from the National Physics Exam (NPE). Their teachers had previously attended a professional development institute which emphasized the practice and philosophy of assessments like the Optics Assessment. The assessment responses were categorized by two raters who used a taxonomy that ranged from simple descriptions to complete explanations. NPE performance was compared using one-way ANOVA, Optics Assessment performance was compared using a chi-square test of homogeneity, and a point-biserial correlation was done to compare qualitative and quantitative performance. The study found that students were unable to use feedback to make a significant change in the quality of their responses, whether revision or subsequent prediction. There was no correlation between content knowledge and qualitative performance. It was concluded that for students to succeed on an assessment of this type, their classroom teachers must be given the time to implement the appropriate instruction. Instruction and assessment of this nature are crucial to the development of science literacy.

High-resolution low-frequency fluctuation map of a multimode laser diode subject to filtered optical feedback via a fiber Bragg grating.

PubMed

Baladi, Fadwa; Lee, Min Won; Burie, Jean-René; Bettiati, Mauro A; Boudrioua, Azzedine; Fischer, Alexis P A

2016-07-01

A highly detailed and extended map of low-frequency fluctuations is established for a high-power multi-mode 980 nm laser diode subject to filtered optical feedback from a fiber Bragg grating. The low-frequency fluctuations limits and substructures exhibit substantial differences with previous works.

Polarization feedback laser stabilization

DOEpatents

Esherick, Peter; Owyoung, Adelbert

1988-01-01

A system for locking two Nd:YAG laser oscillators includes an optical path for feeding the output of one laser into the other with different polarizations. Elliptical polarization is incorporated into the optical path so that the change in polarization that occurs when the frequencies coincide may be detected to provide a feedback signal to control one laser relative to the other.

Electro-optic chaotic system based on the reverse-time chaos theory and a nonlinear hybrid feedback loop.

PubMed

Jiang, Xingxing; Cheng, Mengfan; Luo, Fengguang; Deng, Lei; Fu, Songnian; Ke, Changjian; Zhang, Minming; Tang, Ming; Shum, Ping; Liu, Deming

2016-12-12

A novel electro-optic chaos source is proposed on the basis of the reverse-time chaos theory and an analog-digital hybrid feedback loop. The analog output of the system can be determined by the numeric states of shift registers, which makes the system robust and easy to control. The dynamical properties as well as the complexity dependence on the feedback parameters are investigated in detail. The correlation characteristics of the system are also studied. Two improving strategies which were established in digital field and analog field are proposed to conceal the time-delay signature. The proposed scheme has the potential to be used in radar and optical secure communication systems.

Development of a near-field/confocal polarization microscope for local measurements of anisotropy in organic films

NASA Astrophysics Data System (ADS)

Kosterin, Andrey Valentinovich

2000-10-01

Polarization microscopy is a powerful technique for imaging structure and stress distributions in many transparent materials, and has been particularly useful in morphology studies of polymer films. Recently the possibility of combining polarization imaging with near-field scanning optical microscopy (NSOM) has been demonstrated, offering new opportunities for studying molecular organization with better than 50 nm resolution. However, there are challenges associated with near-field polarization experiments on organic films: (1) the films are susceptible to damage by the near-field probe; (2) the phase shift or retardation (80) is small, often <0.1 rad; (3) interpretation of near-field images is complicated by topography and probe-sample coupling. To address these challenges, we have developed a new combined near-field/confocal polarization microscope and tested its sensitivity to linear birefringence in thin polymer films. For near-field imaging, the microscope employs a commercially available scanhead with cantilevered (bent) optical fiber probes. To study soft samples (point 1), we have modified the scanhead for tapping mode feedback, which eliminates probe-sample shear forces and prolongs the lifetime of the probe, while minimizing damage to the sample. To achieve sensitivity to small phase shifts (point 2), we have implemented the phase modulation (PM) technique in the optical path. Enhanced sensitivity relative to the standard crossed polarizers scheme is achieved because of the better signal-to-noise discrimination common to lock-in detection and because the detected first harmonic intensity, Io , is linearly proportional to deltatheta instead of (deltatheta) 2. To facilitate interpretation of near-field contrast (point 3), we have incorporated near-field and confocal channels in one instrument. This allows consecutive acquisition of both near-field and far-field images on the same sample area. Since the far-field images do not suffer from the same artifacts, they can be used as a source of independent information on sample optical properties. The combined near-field/confocal polarization microscope is discussed in this thesis as well as some of its applications. Specifically we consider the results of polyethylene oxide (PEO) and crosslinked polybutadiene (PB) thin film imaging.

Formative assessment based on an audit and feedback improves nuchal translucency ultrasound image quality.

PubMed

Chalouhi, Gihad E; Salomon, Laurent J; Fontanges, Marianne; Althuser, Marc; Haddad, Georges; Scemama, Olivier; Chabot, Jean-Michel; Duyme, Michel; Fries, Nicolas

2013-09-01

The purpose of this work was to study the impact of an audit and feedback on the quality of routine first-trimester nuchal transparency ultrasound images. Eighty-eight sonographers were each sent 2 different series of 30 consecutive nuchal translucency images at a mean interval of 3 months to a dedicated, protected server for remote double-blind independent analysis based on the new Collège Français d'Echographie Foetale/Centre National de la Recherche Scientifique image-scoring method (https://www.cfef.org/evaluation/ISMCFEFCNRS.pdf). The sonographers were classified as low (score below the median) or high (score above the median) scorers for each series. Before their second evaluation, 73 of the 88 sonographers received a feedback report on their first series of images, whereas the other 15 participants received no feedback. The baseline characteristics of the participants who did and did not receive feedback were comparable. Participants who received feedback increased their average score significantly, from a mean ± SD of 11.1 ± 1.3 to 13.4 ± 1.4 among low scorers (P < .00001) and from 15.1 ± 1.2 to 16.0 ± 1.4 among high scorers (P < .001), whereas no significant change was seen among participants who received no feedback (low scorers, 10.9 ± 1.5 to 12.1 ± 2.0; P = .11; high scorers, 14.7 ± 1.3 to 14.6 ± 1.3; P = .99). The proportion of satisfactory images increased by 48% among low scorers who received feedback. Formative assessment based on a moderately intensive audit and feedback is feasible and effective for improving the quality of routine first-trimester nuchal transparency ultrasound images.

Multimodality optical coherence tomography and fluorescence confocal scanning laser ophthalmoscopy for image-guided feedback of intraocular injections in mouse models

NASA Astrophysics Data System (ADS)

Benavides, Oscar R.; Terrones, Benjamin D.; Leeburg, Kelsey C.; Mehanathan, Sankarathi B.; Levine, Edward M.; Tao, Yuankai K.

2018-02-01

Rodent models are robust tools for understanding human retinal disease and function because of their similarities with human physiology and anatomy and availability of genetic mutants. Optical coherence tomography (OCT) has been well-established for ophthalmic imaging in rodents and enables depth-resolved visualization of structures and image-based surrogate biomarkers of disease. Similarly, fluorescence confocal scanning laser ophthalmoscopy (cSLO) has demonstrated utility for imaging endogenous and exogenous fluorescence and scattering contrast in the mouse retina. Complementary volumetric scattering and en face fluorescence contrast from OCT and cSLO, respectively, enables cellular-resolution longitudinal imaging of changes in ophthalmic structure and function. We present a non-contact multimodal OCT+cSLO small animal imaging system with extended working distance to the pupil, which enables imaging during and after intraocular injection. While injections are routinely performed in mice to develop novel models of ophthalmic diseases and screen novel therapeutics, the location and volume delivered is not precisely controlled and difficult to reproduce. Animals were imaged using a custom-built OCT engine and scan-head combined with a modified commercial cSLO scan-head. Post-injection imaging showed structural changes associated with retinal puncture, including the injection track, a retinal elevation, and detachment of the posterior hyaloid. When combined with imagesegmentation, we believe OCT can be used to precisely identify injection locations and quantify injection volumes. Fluorescence cSLO can provide complementary contrast for either fluorescently labeled compounds or transgenic cells for improved specificity. Our non-contact OCT+cSLO system is uniquely-suited for concurrent imaging with intraocular injections, which may be used for real-time image-guided injections.

Torsional Dynamics of Steerable Needles: Modeling and Fluoroscopic Guidance

PubMed Central

Swensen, John P.; Lin, MingDe; Okamura, Allison M.; Cowan, Noah J.

2017-01-01

Needle insertions underlie a diversity of medical interventions. Steerable needles provide a means by which to enhance existing needle-based interventions and facilitate new ones. Tip-steerable needles follow a curved path and can be steered by twisting the needle base during insertion, but this twisting excites torsional dynamics that introduce a discrepancy between the base and tip twist angles. Here, we model the torsional dynamics of a flexible rod—such as a tip-steerable needle—during subsurface insertion and develop a new controller based on the model. The torsional model incorporates time-varying mode shapes to capture the changing boundary conditions inherent during insertion. Numerical simulations and physical experiments using two distinct setups—stereo camera feedback in semi-transparent artificial tissue and feedback control with real-time X-ray imaging in optically opaque artificial tissue— demonstrate the need to account for torsional dynamics in control of the needle tip. PMID:24860026

Contributions to workload of rotational optical transformations

NASA Technical Reports Server (NTRS)

Atkinson, R. P.; Harrington, T. L.

1985-01-01

An investigation of visuomotor adaptation to optical rotation and optical inversion was conducted. Experiment 1 examined the visuomotor adaptability of subjects to an optically rotating visual world with a univariate repeated measures design. Experiment 1A tested one major prediction of a model of adaptation put forth by Welch who predicted that the aversive drive state that triggers adaptation would be habituated to fairly rapidly. Experiment 2 was conducted to investigate the role of motor activity in adaptation to optical rotation. Specifically, this experiment contrasted the reafference hypothesis and the proprioceptive change hypothesis. Experiment 3 examined the role of cognition, error-corrective feedback, and proprioceptive and/or reafferent feedback in visuomotor adaptation to optical inversion. Implications for research and implications for practice were suggested for all experiments.

Stabilization of self-mode-locked quantum dash lasers by symmetric dual-loop optical feedback

NASA Astrophysics Data System (ADS)

Asghar, Haroon; Wei, Wei; Kumar, Pramod; Sooudi, Ehsan; McInerney, John. G.

2018-02-01

We report experimental studies of the influence of symmetric dual-loop optical feedback on the RF linewidth and timing jitter of self-mode-locked two-section quantum dash lasers emitting at 1550 nm. Various feedback schemes were investigated and optimum levels determined for narrowest RF linewidth and low timing jitter, for single-loop and symmetric dual-loop feedback. Two symmetric dual-loop configurations, with balanced and unbalanced feedback ratios, were studied. We demonstrate that unbalanced symmetric dual loop feedback, with the inner cavity resonant and fine delay tuning of the outer loop, gives narrowest RF linewidth and reduced timing jitter over a wide range of delay, unlike single and balanced symmetric dual-loop configurations. This configuration with feedback lengths 80 and 140 m narrows the RF linewidth by 4-67x and 10-100x, respectively, across the widest delay range, compared to free-running. For symmetric dual-loop feedback, the influence of different power split ratios through the feedback loops was determined. Our results show that symmetric dual-loop feedback is markedly more effective than single-loop feedback in reducing RF linewidth and timing jitter, and is much less sensitive to delay phase, making this technique ideal for applications where robustness and alignment tolerance are essential.

Invited Article: A review of haptic optical tweezers for an interactive microworld exploration

NASA Astrophysics Data System (ADS)

Pacoret, Cécile; Régnier, Stéphane

2013-08-01

This paper is the first review of haptic optical tweezers, a new technique which associates force feedback teleoperation with optical tweezers. This technique allows users to explore the microworld by sensing and exerting picoNewton-scale forces with trapped microspheres. Haptic optical tweezers also allow improved dexterity of micromanipulation and micro-assembly. One of the challenges of this technique is to sense and magnify picoNewton-scale forces by a factor of 1012 to enable human operators to perceive interactions that they have never experienced before, such as adhesion phenomena, extremely low inertia, and high frequency dynamics of extremely small objects. The design of optical tweezers for high quality haptic feedback is challenging, given the requirements for very high sensitivity and dynamic stability. The concept, design process, and specification of optical tweezers reviewed here are focused on those intended for haptic teleoperation. In this paper, two new specific designs as well as the current state-of-the-art are presented. Moreover, the remaining important issues are identified for further developments. The initial results obtained are promising and demonstrate that optical tweezers have a significant potential for haptic exploration of the microworld. Haptic optical tweezers will become an invaluable tool for force feedback micromanipulation of biological samples and nano- and micro-assembly parts.

SPECIAL ISSUE ON OPTICAL PROCESSING OF INFORMATION: Multistability in an acousto-optical system with a frequency feedback

NASA Astrophysics Data System (ADS)

Balakshiĭ, V. I.; Kazar'yan, A. Y.; Lee, A. A.

1995-10-01

An investigation was made of an acousto-optical system with hybrid feedback used to control the frequency of ultrasonic waves excited in an acousto-optical cell. An amplitude transparency, placed in front of a photodetector, ensured a nonlinear dependence of the intensity of the diffracted radiation reaching the detector on the ultrasound frequency. Conditions were found under which this nonlinearity gave rise to multistable states differing in respect of the amplitude, frequency, and direction of propagation of the diffracted beam. An analysis was made of various uses of such a system as an optical channel switch and in stabilisation of the direction of propagation of a light beam.

CHEERS Results from NGC 3393. II. Investigating the Extended Narrow-line Region Using Deep Chandra Observations and Hubble Space Telescope Narrow-line Imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin

The CHandra Extended Emission Line Region Survey (CHEERS) is an X-ray study of nearby active galactic nuclei (AGNs) designed to take full advantage of Chandra 's unique angular resolution by spatially resolving feedback signatures and effects. In the second paper of a series on CHEERS target NGC 3393, we examine deep high-resolution Chandra images and compare them with Hubble Space Telescope narrow-line images of [O iii], [S ii], and H α , as well as previously unpublished mid-ultraviolet (MUV) images. The X-rays provide unprecedented evidence that the S-shaped arms that envelope the nuclear radio outflows extend only ≲0.″2 (≲50 pc)more » across. The high-resolution multiwavelength data suggest that the extended narrow-line region is a complex multiphase structure in the circumnuclear interstellar medium (ISM). Its ionization structure is highly stratified with respect to outflow-driven bubbles in the bicone and varies dramatically on scales of ∼10 pc. Multiple findings show likely contributions from shocks to the feedback in regions where radio outflows from the AGN most directly influence the ISM. These findings include H α evidence for gas compression and extended MUV emission and are in agreement with existing STIS kinematics. Extended filamentary structure in the X-rays and optical suggests the presence of an undetected plasma component, whose existence could be tested with deeper radio observations.« less

Core needle biopsy guidance based on EMOCT imaging (Conference Presentation)

NASA Astrophysics Data System (ADS)

Iftimia, Nicusor V.; Park, Jesung; Maguluri, Gopi

2016-03-01

We present a novel method, based on encoder mapping OCT imaging, for real-time guidance of core biopsy procedures. This method provides real-time feedback to the interventional radiologist, such that he/she can reorient the needle during the biopsy and sample the most representative area of the suspicious mass that is being investigated. This aspect is very important for tailoring therapy to the specific cancer based on biomarker analysis, which will become one of the next big advances in our search for the optimal cancer therapy. To enable individualized treatment, the genetic constitution and the DNA repair status in the affected areas is needed for each patient. Thus, representative sampling of the tumor is needed for analyzing various biomarkers, which are used as a tool to personalize cancer therapy. The encoder-based OCT enables samping of large size masses and provides full control on the imaging probe, which is passed through the bore of the biopsy guidance needle. The OCT image is built gradually, based on the feedback of an optical encoder which senses the incremental movement of the needle with a few microns resolution. Tissue mapping is independent of the needle speed, while it is advanced through the tissue. The OCT frame is analyzed in real-time and tissue cellularity is reported in a very simple manner (pie chart). Our preliminary study on a rabbit model of cancer has demonstrated the capability of this technology for accurately differentiating between viable cancer and heterogeneous or necrotic tissue.

Polarization feedback laser stabilization

DOEpatents

Esherick, P.; Owyoung, A.

1987-09-28

A system for locking two Nd:YAG laser oscillators includes an optical path for feeding the output of one laser into the other with different polarizations. Elliptical polarization is incorporated into the optical path so that the change in polarization that occurs when the frequencies coincide may be detected to provide a feedback signal to control one laser relative to the other. 4 figs.

Chaos synchronization in vertical-cavity surface-emitting laser based on rotated polarization-preserved optical feedback

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nazhan, Salam; Ghassemlooy, Zabih; Busawon, Krishna

2016-01-15

In this paper, the influence of the rotating polarization-preserved optical feedback on the chaos synchronization of a vertical-cavity surface-emitting laser (VCSEL) is investigated experimentally. Two VCSELs' polarization modes (XP) and (YP) are gradually rotated and re-injected back into the VCSEL. The anti-phase dynamics synchronization of the two polarization modes is evaluated using the cross-correlation function. For a fixed optical feedback, a clear relationship is found between the cross-correlation coefficient and the polarization angle θ{sub p}. It is shown that high-quality anti-phase polarization-resolved chaos synchronization is achieved at higher values of θ{sub p}. The maximum value of the cross-correlation coefficient achievedmore » is −0.99 with a zero time delay over a wide range of θ{sub p} beyond 65° with a poor synchronization dynamic at θ{sub p} less than 65°. Furthermore, it is observed that the antiphase irregular oscillation of the XP and YP modes changes with θ{sub p}. VCSEL under the rotating polarization optical feedback can be a good candidate as a chaotic synchronization source for a secure communication system.« less

Continuous parametric feedback cooling of a single atom in an optical cavity

NASA Astrophysics Data System (ADS)

Sames, C.; Hamsen, C.; Chibani, H.; Altin, P. A.; Wilk, T.; Rempe, G.

2018-05-01

We demonstrate a feedback algorithm to cool a single neutral atom trapped inside a standing-wave optical cavity. The algorithm is based on parametric modulation of the confining potential at twice the natural oscillation frequency of the atom, in combination with fast and repetitive atomic position measurements. The latter serve to continuously adjust the modulation phase to a value for which parametric excitation of the atomic motion is avoided. Cooling is limited by the measurement backaction which decoheres the atomic motion after only a few oscillations. Nonetheless, applying this feedback scheme to an ˜5 -kHz oscillation mode increases the average storage time of a single atom in the cavity by a factor of 60 to more than 2 s. In contrast to previous feedback schemes, our algorithm is also capable of cooling a much faster ˜500 -kHz oscillation mode within just microseconds. This demonstrates that parametric cooling is a powerful technique that can be applied in all experiments where optical access is limited.

Recent Progress in Adjustable X-ray Optics for Astronomy

NASA Technical Reports Server (NTRS)

Reid, Paul B.; Allured, Ryan; Cotroneo, Vincenzo; McMuldroch, Stuart; Marquez, Vanessa; Schwartz, Daniel A.; Vikhlinin, Alexey; ODell, Stephen L.; Ramsey, Brian; Trolier-McKinstry, Susan;

Image registration: enabling technology for image guided surgery and therapy.

PubMed

Sauer, Frank

2005-01-01

Imaging looks inside the patient's body, exposing the patient's anatomy beyond what is visible on the surface. Medical imaging has a very successful history for medical diagnosis. It also plays an increasingly important role as enabling technology for minimally invasive procedures. Interventional procedures (e.g. catheter based cardiac interventions) are traditionally supported by intra-procedure imaging (X-ray fluoro, ultrasound). There is realtime feedback, but the images provide limited information. Surgical procedures are traditionally supported with pre-operative images (CT, MR). The image quality can be very good; however, the link between images and patient has been lost. For both cases, image registration can play an essential role -augmenting intra-op images with pre-op images, and mapping pre-op images to the patient's body. We will present examples of both approaches from an application oriented perspective, covering electrophysiology, radiation therapy, and neuro-surgery. Ultimately, as the boundaries between interventional radiology and surgery are becoming blurry, also the different methods for image guidance will merge. Image guidance will draw upon a combination of pre-op and intra-op imaging together with magnetic or optical tracking systems, and enable precise minimally invasive procedures. The information is registered into a common coordinate system, and allows advanced methods for visualization such as augmented reality or advanced methods for therapy delivery such as robotics.

Investigation of Space Interferometer Control Using Imaging Sensor Output Feedback

NASA Technical Reports Server (NTRS)

Leitner, Jesse A.; Cheng, Victor H. L.

2003-01-01

Numerous space interferometry missions are planned for the next decade to verify different enabling technologies towards very-long-baseline interferometry to achieve high-resolution imaging and high-precision measurements. These objectives will require coordinated formations of spacecraft separately carrying optical elements comprising the interferometer. High-precision sensing and control of the spacecraft and the interferometer-component payloads are necessary to deliver sub-wavelength accuracy to achieve the scientific objectives. For these missions, the primary scientific product of interferometer measurements may be the only source of data available at the precision required to maintain the spacecraft and interferometer-component formation. A concept is studied for detecting the interferometer's optical configuration errors based on information extracted from the interferometer sensor output. It enables precision control of the optical components, and, in cases of space interferometers requiring formation flight of spacecraft that comprise the elements of a distributed instrument, it enables the control of the formation-flying vehicles because independent navigation or ranging sensors cannot deliver the high-precision metrology over the entire required geometry. Since the concept can act on the quality of the interferometer output directly, it can detect errors outside the capability of traditional metrology instruments, and provide the means needed to augment the traditional instrumentation to enable enhanced performance. Specific analyses performed in this study include the application of signal-processing and image-processing techniques to solve the problems of interferometer aperture baseline control, interferometer pointing, and orientation of multiple interferometer aperture pairs.

Noninvasive optical imaging of resistance training adaptations in human muscle

NASA Astrophysics Data System (ADS)

Warren, Robert V.; Cotter, Joshua; Ganesan, Goutham; Le, Lisa; Agustin, Janelle P.; Duarte, Bridgette; Cutler, Kyle; O'Sullivan, Thomas; Tromberg, Bruce J.

2017-12-01

A quantitative and dynamic analysis of skeletal muscle structure and function can guide training protocols and optimize interventions for rehabilitation and disease. While technologies exist to measure body composition, techniques are still needed for quantitative, long-term functional imaging of muscle at the bedside. We evaluate whether diffuse optical spectroscopic imaging (DOSI) can be used for long-term assessment of resistance training (RT). DOSI measures of tissue composition were obtained from 12 adults before and after 5 weeks of training and compared to lean mass fraction (LMF) from dual-energy X-ray absorptiometry (DXA). Significant correlations were detected between DXA LMF and DOSI-measured oxy-hemo/myoglobin, deoxy-hemo/myoglobin, total-hemo/myoglobin, water, and lipid. RT-induced increases of ˜6% in oxy-hemo/myoglobin (3.4±1.0 μM, p=0.00314) and total-hemo/myoglobin (4.9±1.1 μM, p=0.00024) from the medial gastrocnemius were detected with DOSI and accompanied by ˜2% increases in lean soft tissue mass (36.4±12.4 g, p=0.01641) and ˜60% increases in 1 rep-max strength (41.5±6.2 kg, p = 1.9E-05). DOSI measures of vascular and/or muscle changes combined with correlations between DOSI and DXA suggest that quantitative diffuse optical methods can be used to evaluate body composition, provide feedback on long-term interventions, and generate new insight into training-induced muscle adaptations.

Quantitative phase measurement for wafer-level optics

NASA Astrophysics Data System (ADS)

Qu, Weijuan; Wen, Yongfu; Wang, Zhaomin; Yang, Fang; Huang, Lei; Zuo, Chao

2015-07-01

Wafer-level-optics now is widely used in smart phone camera, mobile video conferencing or in medical equipment that require tiny cameras. Extracting quantitative phase information has received increased interest in order to quantify the quality of manufactured wafer-level-optics, detect defective devices before packaging, and provide feedback for manufacturing process control, all at the wafer-level for high-throughput microfabrication. We demonstrate two phase imaging methods, digital holographic microscopy (DHM) and Transport-of-Intensity Equation (TIE) to measure the phase of the wafer-level lenses. DHM is a laser-based interferometric method based on interference of two wavefronts. It can perform a phase measurement in a single shot. While a minimum of two measurements of the spatial intensity of the optical wave in closely spaced planes perpendicular to the direction of propagation are needed to do the direct phase retrieval by solving a second-order differential equation, i.e., with a non-iterative deterministic algorithm from intensity measurements using the Transport-of-Intensity Equation (TIE). But TIE is a non-interferometric method, thus can be applied to partial-coherence light. We demonstrated the capability and disability for the two phase measurement methods for wafer-level optics inspection.

Optical bending sensor using distributed feedback solid state dye lasers on optical fiber.

PubMed

Kubota, Hiroyuki; Oomi, Soichiro; Yoshioka, Hiroaki; Watanabe, Hirofumi; Oki, Yuji

2012-07-02

Novel type of optical fiber sensor was proposed and demonstrated. The print-like fabrication technique fabricates multiple distributed feedback solid state dye lasers on a polymeric optical fiber (POF) with tapered coupling. This multi-active-sidecore structure was easily fabricated and provides multiple functions. Mounting the lasers on the same point of a multimode POF demonstrated a bending radius sensitivity of 20 m without any supports. Two axis directional sensing without cross talk was also confirmed. A more complicated mounting formation can demonstrate a twisted POF. The temperature property of the sensor was also studied, and elimination of the temperature influence was experimentally attained.

Rapid feedback control and stabilization of an optical tweezers with a budget microcontroller

NASA Astrophysics Data System (ADS)

Nino, Daniel; Wang, Haowei; Milstein, Joshua N.

2014-09-01

Laboratories ranging the scientific disciplines employ feedback control to regulate variables within their experiments, from the flow of liquids within a microfluidic device to the temperature within a cell incubator. We have built an inexpensive, yet fast and rapidly deployed, feedback control system that is straightforward and flexible to implement from a commercially available Arduino Due microcontroller. This is in comparison with the complex, time-consuming and often expensive electronics that are commonly implemented. As an example of its utility, we apply our feedback controller to the task of stabilizing the main trapping laser of an optical tweezers. The feedback controller, which is inexpensive yet fast and rapidly deployed, was implemented from hacking an open source Arduino Due microcontroller. Our microcontroller based feedback system can stabilize the laser intensity to a few tenths of a per cent at 200 kHz, which is an order of magnitude better than the laser's base specifications, illustrating the utility of these devices.

Continuous wave operation of quantum cascade lasers with frequency-shifted feedback

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyakh, A., E-mail: arkadiy.lyakh@ucf.edu; NanoScience Technology Center, University of Central Florida, 12424 Research Pkwy, Orlando, FL 32826; College of Optics and Photonics, University of Central Florida, 304 Scorpius St, Orlando, FL 32826

2016-01-15

Operation of continuous wave quantum cascade lasers with a frequency-shifted feedback provided by an acousto-optic modulator is reported. Measured linewidth of 1.7 cm{sup −1} for these devices, under CW operating conditions, was in a good agreement with predictions of a model based on frequency-shifted feedback seeded by spontaneous emission. Linewidth broadening was observed for short sweep times, consistent with sound wave grating period variation across the illuminated area on the acousto-optic modulator. Standoff detection capability of the AOM-based QCL setup was demonstrated for several solid materials.

X-Ray Scattering Echoes and Ghost Halos from the Intergalactic Medium: Relation to the Nature of AGN Variability

NASA Astrophysics Data System (ADS)

Corrales, Lia

2015-05-01

X-ray bright quasars might be used to trace dust in the circumgalactic and intergalactic medium through the phenomenon of X-ray scattering, which is observed around Galactic objects whose light passes through a sufficient column of interstellar gas and dust. Of particular interest is the abundance of gray dust larger than 0.1 μ m, which is difficult to detect at other wavelengths. To calculate X-ray scattering from large grains, one must abandon the traditional Rayleigh-Gans approximation. The Mie solution for the X-ray scattering optical depth of the universe is ∼ 1%. This presents a great difficulty for distinguishing dust scattered photons from the point source image of Chandra, which is currently unsurpassed in imaging resolution. The variable nature of AGNs offers a solution to this problem, as scattered light takes a longer path and thus experiences a time delay with respect to non-scattered light. If an AGN dims significantly (≳ 3 dex) due to a major feedback event, the Chandra point source image will be suppressed relative to the scattering halo, and an X-ray echo or ghost halo may become visible. I estimate the total number of scattering echoes visible by Chandra over the entire sky: {{N}ech}∼ {{10}3}({{ν }fb}/y{{r}-1}), where {{ν }fb} is the characteristic frequency of feedback events capable of dimming an AGN quickly.

Structural control sensors for the CASES GTF

NASA Technical Reports Server (NTRS)

Davis, Hugh W.; Bukley, Angelia P.

1993-01-01

CASES (Controls, Astrophysics and Structures Experiment in Space) is a proposed space experiment to collect x-ray images of the galactic center and solar disk with unprecedented resolution. This requires precision pointing and suppression of vibrations in the long flexible structure that comprises the 32-m x-ray telescope optical bench. Two separate electro-optical sensor systems are provided for the ground test facility (GTF). The Boom Motion Tracker (BMT) measures eigenvector data for post-mission use in system identification. The Tip Displacement Sensor (TDS) measures boom tip position and is used as feedback for the closed-loop control system that stabilizes the boom. Both the BMT and the TDS have met acceptance specifications and were delivered to MSFC in February 1992. This paper describes the sensor concept, the sensor configuration as implemented in the GTF, and the results of characterization and performance testing.

Widely tunable quantum cascade lasers for spectroscopic sensing

NASA Astrophysics Data System (ADS)

Wagner, J.; Ostendorf, R.; Grahmann, J.; Merten, A.; Hugger, S.; Jarvis, J.-P.; Fuchs, F.; Boskovic, D.; Schenk, H.

2015-01-01

In this paper recent advances in broadband-tuneable mid-infrared (MIR) external-cavity quantum cascade lasers (EC-QCL) technology are reported as well as their use in spectroscopic process analysis and imaging stand-off detection of hazardous substances, such as explosive and related precursors. First results are presented on rapid scan EC-QCL, employing a custom-made MOEMS scanning grating in Littrow-configuration as wavelength-selective optical feedback element. This way, a scanning rate of 1 kHz was achieved, which corresponds to 2000 full wavelength scans per second. Furthermore, exemplary case studies of EC-QCL based MIR spectroscopy will be presented. These include timeresolved analysis of catalytic reactions in chemical process control, as well as imaging backscattering spectroscopy for the detection of residues of explosives and related precursors in a relevant environment.

All-Union Conference on Laser Optics, 4th, Leningrad, USSR, January 13-18, 1984, Proceedings

NASA Astrophysics Data System (ADS)

Bukhenskii, M. F.

1984-08-01

The papers presented in this volume provide an overview of current theoretical and experimental research in laser optics. Topics discussed include electronically controlled tunable lasers, nonlinear phenomena in fiber-optic waveguides, holographic distributed-feedback dye lasers, and new developments in solid-state lasers. Papers are also presented on the generation of picosecond pulses through self-Q-switching in a distributed-feedback laser, temporal compression of light pulses during stimulated backscattering, and optimization of second harmonic generation in a multimode Nd:glass laser.

Some aspects of optical feedback with cadmium sulfide and related photoconductors. [for extended frequency response

NASA Technical Reports Server (NTRS)

Katzberg, S. J.

1974-01-01

A primary limitation of many solid state photoconductors used in electro-optical systems is their slow response in converting varying light intensities into electrical signals. An optical feedback technique is presented which can extend the frequency response of systems that use these detectors by orders of magnitude without adversely affecting overall signal-to-noise ratio performance. The technique is analyzed to predict the improvement possible and a system is implemented using cadmium sulfide to demonstrate the effectiveness of the technique and the validity of the analysis.

Direct laser additive fabrication system with image feedback control

DOEpatents

Griffith, Michelle L.; Hofmeister, William H.; Knorovsky, Gerald A.; MacCallum, Danny O.; Schlienger, M. Eric; Smugeresky, John E.

2002-01-01

A closed-loop, feedback-controlled direct laser fabrication system is disclosed. The feedback refers to the actual growth conditions obtained by real-time analysis of thermal radiation images. The resulting system can fabricate components with severalfold improvement in dimensional tolerances and surface finish.

Distributed feedback imprinted electrospun fiber lasers.

PubMed

Persano, Luana; Camposeo, Andrea; Del Carro, Pompilio; Fasano, Vito; Moffa, Maria; Manco, Rita; D'Agostino, Stefania; Pisignano, Dario

2014-10-01

Imprinted, distributed feedback lasers are demonstrated on individual, active electrospun polymer nanofibers. In addition to advantages related to miniaturization, optical confinement and grating nanopatterning lead to a significant threshold reduction compared to conventional thin-film lasers. The possibility of imprinting arbitrary photonic crystal geometries on electrospun lasing nanofibers opens new opportunities for realizing optical circuits and chips. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The implementation of an AR (augmented reality) approach to support mammographic interpretation training: an initial feasibility study

NASA Astrophysics Data System (ADS)

Tang, Qiang; Chen, Yan; Gale, Alastair G.

2017-03-01

Appropriate feedback plays an important role in optimising mammographic interpretation training whilst also ensuring good interpretation performance. The traditional keyboard, mouse and workstation technical approach has a critical limitation in providing supplementary image-related information and providing complex feedback in real time. Augmented Reality (AR) provides a possible superior approach in this situation, as feedback can be provided directly overlaying the displayed mammographic images so making a generic approach which can also be vendor neutral. In this study, radiological feedback was dynamically remapped virtually into the real world, using perspective transformation, in order to provide a richer user experience in mammographic interpretation training. This is an initial attempt of an AR approach to dynamically superimpose pre-defined feedback information of a DICOM image on top of a radiologist's view, whilst the radiologist is examining images on a clinical workstation. The study demonstrates the feasibility of the approach, although there are limitations on interactive operations which are due to the hardware used. The results of this fully functional approach provide appropriate feedback/image correspondence in a simulated mammographic interpretation environment. Thus, it is argued that employing AR is a feasible way to provide rich feedback in the delivery of mammographic interpretation training.

Asymmetric noise sensitivity of pulse trains in an excitable microlaser with delayed optical feedback

NASA Astrophysics Data System (ADS)

Terrien, Soizic; Krauskopf, Bernd; Broderick, Neil G. R.; Andréoli, Louis; Selmi, Foued; Braive, Rémy; Beaudoin, Grégoire; Sagnes, Isabelle; Barbay, Sylvain

2017-10-01

A semiconductor micropillar laser with delayed optical feedback is considered. In the excitable regime, we show that a single optical perturbation can trigger a train of pulses that is sustained for a finite duration. The distribution of the pulse train duration exhibits an exponential behavior characteristic of a noise-induced process driven by uncorrelated white noise present in the system. The comparison of experimental observations with theoretical and numerical analysis of a minimal model yields excellent agreement. Importantly, the random switch-off process takes place between two attractors of different nature: an equilibrium and a periodic orbit. Our analysis shows that there is a small time window during which the pulsations are very sensitive to noise, and this explains the observed strong bias toward switch-off. These results raise the possibility of all optical control of the pulse train duration that may have an impact for practical applications in photonics and may also apply to the dynamics of other noise-driven excitable systems with delayed feedback.

Optical feedback cavity-enhanced absorption spectroscopy with a 3.24 μm interband cascade laser

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manfred, K. M.; Ritchie, G. A. D.; Lang, N.

2015-06-01

The development of interband cascade lasers (ICLs) has made the strong C-H transitions in the 3 μm spectral region increasingly accessible. We present the demonstration of a single mode distributed feedback ICL coupled to a V-shaped optical cavity in an optical feedback cavity-enhanced absorption spectroscopy (OF-CEAS) experiment. We achieved a minimum detectable absorption coefficient, α{sub min}, of (7.1±0.2)×10{sup −8} cm{sup −1} for a spectrum of CH{sub 4} at 3.24 μm with a two second acquisition time (100 scans averaged). This corresponds to a detection limit of 3 ppb CH{sub 4} at atmospheric pressure, which is comparable to previously reported OF-CEAS instruments with diodemore » lasers or quantum cascade lasers. The ability to frequency lock an ICL source in the important 3 μm region to an optical cavity holds great promise for future spectroscopic applications.« less

Structural and Functional Biomedical Imaging Using Polarization-Based Optical Coherence Tomography

NASA Astrophysics Data System (ADS)

Black, Adam J.

Biomedical imaging has had an enormous impact in medicine and research. There are numerous imaging modalities covering a large range of spatial and temporal scales, penetration depths, along with indicators for function and disease. As these imaging technologies mature, the quality of the images they produce increases to resolve finer details with greater contrast at higher speeds which aids in a faster, more accurate diagnosis in the clinic. In this dissertation, polarization-based optical coherence tomography (OCT) systems are used and developed to image biological structure and function with greater speeds, signal-to-noise (SNR) and stability. OCT can image with spatial and temporal resolutions in the micro range. When imaging any sample, feedback is very important to verify the fidelity and desired location on the sample being imaged. To increase frame rates for display as well as data throughput, field-programmable gate arrays (FPGAs) were used with custom algorithms to realize real-time display and streaming output for continuous acquisition of large datasets of swept-source OCT systems. For spectral domain (SD) OCT systems, significant increases in signal-to-noise ratios were achieved from a custom balanced detection (BD) OCT system. The BD system doubled measured signals while reducing common term. For functional imaging, a real-time directed scanner was introduced to visualize the 3D image of a sample to identify regions of interest prior to recording. Elucidating the characteristics of functional OCT signals with the aid of simulations, novel processing methods were also developed to stabilize samples being imaged and identify possible origins of functional signals being measured. Polarization-sensitive OCT was used to image cardiac tissue before and after clearing to identify the regions of vascular perfusion from a coronary artery. The resulting 3D image provides a visualization of the perfusion boundaries for the tissue that would be damaged from a myocardial infarction to possibly identity features that lead to fatal cardiac arrhythmias. 3D functional imaging was used to measure functional retinal activity from a light stimulus. In some cases, single trial responses were possible; measured at the outer segment of the photoreceptor layer. The morphology and time-course of these signals are similar to the intrinsic optical signals reported from phototransduction. Assessing function in the retina could aid in early detection of degenerative diseases of the retina, such as glaucoma and macular degeneration.

Self-Management of Patient Body Position, Pose, and Motion Using Wide-Field, Real-Time Optical Measurement Feedback: Results of a Volunteer Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parkhurst, James M.; Price, Gareth J., E-mail: gareth.price@christie.nhs.uk; Faculty of Medical and Human Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester

2013-12-01

Purpose: We present the results of a clinical feasibility study, performed in 10 healthy volunteers undergoing a simulated treatment over 3 sessions, to investigate the use of a wide-field visual feedback technique intended to help patients control their pose while reducing motion during radiation therapy treatment. Methods and Materials: An optical surface sensor is used to capture wide-area measurements of a subject's body surface with visualizations of these data displayed back to them in real time. In this study we hypothesize that this active feedback mechanism will enable patients to control their motion and help them maintain their setup posemore » and position. A capability hierarchy of 3 different level-of-detail abstractions of the measured surface data is systematically compared. Results: Use of the device enabled volunteers to increase their conformance to a reference surface, as measured by decreased variability across their body surfaces. The use of visual feedback also enabled volunteers to reduce their respiratory motion amplitude to 1.7 ± 0.6 mm compared with 2.7 ± 1.4 mm without visual feedback. Conclusions: The use of live feedback of their optically measured body surfaces enabled a set of volunteers to better manage their pose and motion when compared with free breathing. The method is suitable to be taken forward to patient studies.« less

A unified framework for image retrieval using keyword and visual features.

PubMed

Jing, Feng; Li, Mingling; Zhang, Hong-Jiang; Zhang, Bo

2005-07-01

In this paper, a unified image retrieval framework based on both keyword annotations and visual features is proposed. In this framework, a set of statistical models are built based on visual features of a small set of manually labeled images to represent semantic concepts and used to propagate keywords to other unlabeled images. These models are updated periodically when more images implicitly labeled by users become available through relevance feedback. In this sense, the keyword models serve the function of accumulation and memorization of knowledge learned from user-provided relevance feedback. Furthermore, two sets of effective and efficient similarity measures and relevance feedback schemes are proposed for query by keyword scenario and query by image example scenario, respectively. Keyword models are combined with visual features in these schemes. In particular, a new, entropy-based active learning strategy is introduced to improve the efficiency of relevance feedback for query by keyword. Furthermore, a new algorithm is proposed to estimate the keyword features of the search concept for query by image example. It is shown to be more appropriate than two existing relevance feedback algorithms. Experimental results demonstrate the effectiveness of the proposed framework.

Real-time gas sensing based on optical feedback in a terahertz quantum-cascade laser.

PubMed

Hagelschuer, Till; Wienold, Martin; Richter, Heiko; Schrottke, Lutz; Grahn, Holger T; Hübers, Heinz-Wilhelm

2017-11-27

We report on real-time gas sensing with a terahertz quantum-cascade laser (QCL). The method is solely based on the modulation of the external cavity length, exploiting the intermediate optical feedback regime. While the QCL is operated in continuous-wave mode, optical feedback results in a change of the QCL frequency as well as its terminal voltage. The first effect is exploited to tune the lasing frequency across a molecular absorption line. The second effect is used for the detection of the self-mixing signal. This allows for fast measurement times on the order of 10 ms per spectrum and for real-time measurements of gas concentrations with a rate of 100 Hz. This technique is demonstrated with a mixture of D 2 O and CH 3 OD in an absorption cell.

A Miniature Forward-imaging B-scan Optical Coherence Tomography Probe to Guide Real-time Laser Ablation

PubMed Central

Li, Zhuoyan; Shen, Jin H.; Kozub, John A.; Prasad, Ratna; Lu, Pengcheng; Joos, Karen M.

2014-01-01

Background and Objective Investigations have shown that pulsed lasers tuned to 6.1 μm in wavelength are capable of ablating ocular and neural tissue with minimal collateral damage. This study investigated whether a miniature B-scan forward-imaging optical coherence tomography (OCT) probe can be combined with the laser to provide real-time visual feedback during laser incisions. Study Design/Methods and Materials A miniature 25-gauge B-scan forward-imaging OCT probe was developed and combined with a 250 μm hollow-glass waveguide to permit delivery of 6.1 μm laser energy. A gelatin mixture and both porcine corneal and retinal tissues were simultaneously imaged and lased (6.1 μm, 10 Hz, 0.4-0.7 mJ) through air. The ablation studies were observed and recorded in real time. The crater dimensions were measured using OCT imaging software (Bioptigen, Durham, NC). Histological analysis was performed on the ocular tissues. Results The combined miniature forward-imaging OCT and mid-infrared laser-delivery probe successfully imaged real-time tissue ablation in gelatin, corneal tissue, and retinal tissue. Application of a constant number of 60 pulses at 0.5 mJ/pulse to the gelatin resulted in a mean crater depth of 123 ± 15 μm. For the corneal tissue, there was a significant correlation between the number of pulses used and depth of the lased hole (Pearson correlation coefficient = 0.82; P = 0.0002). Histological analysis of the cornea and retina tissues showed discrete holes with minimal thermal damage. Conclusions A combined miniature OCT and laser -delivery probe can monitor real-time tissue laser ablation. With additional testing and improvements, this novel instrument has the future possibility of effectively guiding surgeries by simultaneously imaging and ablating tissue. PMID:24648326

Modulation of ventral striatal activity by cognitive effort

PubMed Central

Dobryakova, Ekaterina; Jessup, Ryan K; Tricomi, Elizabeth

2016-01-01

Effort discounting theory suggests that the value of a reward should be lower if it was effortful to obtain, whereas contrast theory suggests that the contrast between the costly effort and the reward makes the reward seem more valuable. To test these alternative hypotheses, we used functional magnetic resonance imaging (fMRI) as participants engaged in feedback-based learning that required low or high cognitive effort to obtain positive feedback, while the objective amount of information provided by feedback remained constant. In the low effort condition, a single image was presented with four response options. In the high effort condition, two images were presented, each with two response options, and correct feedback was presented only when participants responded correctly to both of the images. Accuracy was significantly lower for the high effort condition, and all participants reported that the high effort condition was more difficult. A region of the ventral striatum selected for sensitivity to feedback value also showed increased activation to feedback presentation associated with the high effort condition relative to the low effort condition, when controlling for activation from corresponding control conditions where feedback was random. These results suggest that increased cognitive effort produces corresponding increases in positive feedback-related ventral striatum activity, in line with the predictions made by contrast theory. The accomplishment of obtaining a hard-earned intrinsic reward, such as positive feedback, may be particularly likely to promote reward-related brain activity. PMID:27989778

Web-based, GPU-accelerated, Monte Carlo simulation and visualization of indirect radiation imaging detector performance.

PubMed

Dong, Han; Sharma, Diksha; Badano, Aldo

2014-12-01

Monte Carlo simulations play a vital role in the understanding of the fundamental limitations, design, and optimization of existing and emerging medical imaging systems. Efforts in this area have resulted in the development of a wide variety of open-source software packages. One such package, hybridmantis, uses a novel hybrid concept to model indirect scintillator detectors by balancing the computational load using dual CPU and graphics processing unit (GPU) processors, obtaining computational efficiency with reasonable accuracy. In this work, the authors describe two open-source visualization interfaces, webmantis and visualmantis to facilitate the setup of computational experiments via hybridmantis. The visualization tools visualmantis and webmantis enable the user to control simulation properties through a user interface. In the case of webmantis, control via a web browser allows access through mobile devices such as smartphones or tablets. webmantis acts as a server back-end and communicates with an NVIDIA GPU computing cluster that can support multiuser environments where users can execute different experiments in parallel. The output consists of point response and pulse-height spectrum, and optical transport statistics generated by hybridmantis. The users can download the output images and statistics through a zip file for future reference. In addition, webmantis provides a visualization window that displays a few selected optical photon path as they get transported through the detector columns and allows the user to trace the history of the optical photons. The visualization tools visualmantis and webmantis provide features such as on the fly generation of pulse-height spectra and response functions for microcolumnar x-ray imagers while allowing users to save simulation parameters and results from prior experiments. The graphical interfaces simplify the simulation setup and allow the user to go directly from specifying input parameters to receiving visual feedback for the model predictions.

Single-Mode, Distributed Feedback Interband Cascade Lasers

NASA Technical Reports Server (NTRS)

Frez, Clifford F. (Inventor); Borgentun, Carl E. (Inventor); Briggs, Ryan M. (Inventor); Bagheri, Mahmood (Inventor); Forouhar, Siamak (Inventor)

2016-01-01

Single-mode, distributed feedback interband cascade lasers (ICLs) using distributed-feedback gratings (e.g., lateral Bragg gratings) and methods of fabricating such ICLs are provided. The ICLs incorporate distributed-feedback gratings that are formed above the laser active region and adjacent the ridge waveguide (RWG) of the ICL. The ICLs may incorporate a double-ridge system comprising an optical confinement structure (e.g., a RWG) disposed above the laser active region that comprises the first ridge of the double ridge system, a DFB grating (e.g., lateral Bragg grating) disposed above the laser active region and adjacent the optical confinement structure, and an electric confinement structure that passes at least partially through the laser active region and that defines the boundary of the second ridge comprises and the termination of the DFB grating.

Variable Shadow Screens for Imaging Optical Devices

NASA Technical Reports Server (NTRS)

Lu, Ed; Chretien, Jean L.

2004-01-01

Variable shadow screens have been proposed for reducing the apparent brightnesses of very bright light sources relative to other sources within the fields of view of diverse imaging optical devices, including video and film cameras and optical devices for imaging directly into the human eye. In other words, variable shadow screens would increase the effective dynamic ranges of such devices. Traditionally, imaging sensors are protected against excessive brightness by use of dark filters and/or reduction of iris diameters. These traditional means do not increase dynamic range; they reduce the ability to view or image dimmer features of an image because they reduce the brightness of all parts of an image by the same factor. On the other hand, a variable shadow screen would darken only the excessively bright parts of an image. For example, dim objects in a field of view that included the setting Sun or bright headlights could be seen more readily in a picture taken through a variable shadow screen than in a picture of the same scene taken through a dark filter or a narrowed iris. The figure depicts one of many potential variations of the basic concept of the variable shadow screen. The shadow screen would be a normally transparent liquid-crystal matrix placed in front of a focal-plane array of photodetectors in a charge-coupled-device video camera. The shadow screen would be placed far enough from the focal plane so as not to disrupt the focal-plane image to an unacceptable degree, yet close enough so that the out-of-focus shadows cast by the screen would still be effective in darkening the brightest parts of the image. The image detected by the photodetector array itself would be used as feedback to drive the variable shadow screen: The video output of the camera would be processed by suitable analog and/or digital electronic circuitry to generate a negative partial version of the image to be impressed on the shadow screen. The parts of the shadow screen in front of those parts of the image with brightness below a specified threshold would be left transparent; the parts of the shadow screen in front of those parts of the image where the brightness exceeded the threshold would be darkened by an amount that would increase with the excess above the threshold.

Development of optical fiber Bragg grating force-reflection sensor system of medical application for safe minimally invasive robotic surgery

NASA Astrophysics Data System (ADS)

Song, Hoseok; Kim, Kiyoung; Lee, Jungju

2011-07-01

Force feedback plays a very important role in medical surgery. In minimally invasive surgery (MIS), however, the very long and stiff bars of surgical instruments greatly diminish force feedback for the surgeon. In the case of minimally invasive robotic surgery (MIRS), force feedback is totally eliminated. Previous researchers have reported that the absence of force feedback increased the average force magnitude applied to the tissue by at least 50%, and increased the peak force magnitude by at least a factor of two. Therefore, it is very important to provide force information in MIRS. Recently, many sensors are being developed for MIS and MIRS, but some obstacles to their application in actual medical surgery must be surmounted. The most critical problems are size limit and sterilizability. Optical fiber sensors are among the most suitable sensors for the surgical environment. The optical fiber Bragg grating (FBG) sensor, in particular, offers an important additional advantage over other optical fiber sensors in that it is not influenced by the intensity of the light source. In this paper, we present the initial results of a study on the application of a FBG sensor to measure reflected forces in MIRS environments and suggest the possibility of successful application to MIRS systems.

Phase-Shifted Laser Feedback Interferometry

NASA Technical Reports Server (NTRS)

Ovryn, Benjie

1999-01-01

Phase-shifted, laser feedback interferometry is a new diagnostic tool developed at the NASA Lewis Research Center under the Advanced Technology Development (ATD) Program directed by NASA Headquarters Microgravity Research Division. It combines the principles of phase-shifting interferometry (PSI) and laser-feedback interferometry (LFI) to produce an instrument that can quantify both optical path length changes and sample reflectivity variations. In a homogenous medium, the optical path length between two points is the product of the index of refraction and the geometric distance between the two points. LFI differs from other forms of interferometry by using the laser as both the source and the phase detector. In LFI, coherent feedback of the incident light either reflected directly from a surface or reflected after transmission through a region of interest will modulate the output intensity of the laser. The combination of PSI and LFI has produced a robust instrument, based on a low-power helium-neon (HeNe) gas laser, with a high dynamic range that can be used to measure either static or oscillatory changes of the optical path length. Small changes in optical path length are limited by the fraction of a fringe that can be measured; we can measure nonoscillatory changes with a root mean square (rms) error of the wavelength/1000 without averaging.

Fault tolerant function of dynamic refreshing holographic memory with shutter-less optical feedback circuit

NASA Astrophysics Data System (ADS)

Okamoto, Atsushi; Ito, Terumasa; Bunsen, Masatoshi; Takayama, Yoshihisa

2005-11-01

The optical system, consisting of two photorefractive memories and a shutter-less optical feedback circuit, will be demonstrated to function as data mirroring. This function is known to automatically detect the data dropout and restore data, using unimpaired data in another memory, in the event that part or all of the data in either of them were lost for some reason. This memory system also can cope with a damaged hologram, a result of reading beams, which is a disadvantage of rewritable photorefractive memory, to ensure non-destructive holographic reading. It can be achieved by using no electronic circuits or mechanical structures; our optical experimental method in particular obtains this basic action.

Loop Mirror Laser Neural Network with a Fast Liquid-Crystal Display

NASA Astrophysics Data System (ADS)

Mos, Evert C.; Schleipen, Jean J. H. B.; de Waardt, Huug; Khoe, Djan G. D.

1999-07-01

In our laser neural network (LNN) all-optical threshold action is obtained by application of controlled optical feedback to a laser diode. Here an extended experimental LNN is presented with as many as 32 neurons and 12 inputs. In the setup we use a fast liquid-crystal display to implement an optical matrix vector multiplier. This display, based on ferroelectric liquid-crystal material, enables us to present 125 training examples s to the LNN. To maximize the optical feedback efficiency of the setup, a loop mirror is introduced. We use a -rule learning algorithm to train the network to perform a number of functions toward the application area of telecommunication data switching.

Silicon photonic dynamic optical channel leveler with external feedback loop.

PubMed

Doylend, J K; Jessop, P E; Knights, A P

2010-06-21

We demonstrate a dynamic optical channel leveler composed of a variable optical attenuator (VOA) integrated monolithically with a defect-mediated photodiode in a silicon photonic waveguide device. An external feedback loop mimics an analog circuit such that the photodiode directly controls the VOA to provide blind channel leveling within +/-1 dB across a 7-10 dB dynamic range for wavelengths from 1530 nm to 1570 nm. The device consumes approximately 50 mW electrical power and occupies a 6 mm x 0.1 mm footprint per channel. Dynamic leveling is accomplished without tapping optical power from the output path to the photodiode and thus the loss penalty is minimized.

There is more to accommodation of the eye than simply minimizing retinal blur

PubMed Central

Marín-Franch, I.; Del Águila-Carrasco, A. J.; Bernal-Molina, P.; Esteve-Taboada, J. J.; López-Gil, N.; Montés-Micó, R.; Kruger, P. B.

2017-01-01

Eyes of children and young adults change their optical power to focus nearby objects at the retina. But does accommodation function by trial and error to minimize blur and maximize contrast as is generally accepted? Three experiments in monocular and monochromatic vision were performed under two conditions while aberrations were being corrected. In the first condition, feedback was available to the eye from both optical vergence and optical blur. In the second, feedback was only available from target blur. Accommodation was less precise for the second condition, suggesting that it is more than a trial-and-error function. Optical vergence itself seems to be an important cue for accommodation. PMID:29082097

Automatic alignment of double optical paths in excimer laser amplifier

NASA Astrophysics Data System (ADS)

Wang, Dahui; Zhao, Xueqing; Hua, Hengqi; Zhang, Yongsheng; Hu, Yun; Yi, Aiping; Zhao, Jun

2013-05-01

A kind of beam automatic alignment method used for double paths amplification in the electron pumped excimer laser system is demonstrated. In this way, the beams from the amplifiers can be transferred along the designated direction and accordingly irradiate on the target with high stabilization and accuracy. However, owing to nonexistence of natural alignment references in excimer laser amplifiers, two cross-hairs structure is used to align the beams. Here, one crosshair put into the input beam is regarded as the near-field reference while the other put into output beam is regarded as the far-field reference. The two cross-hairs are transmitted onto Charge Coupled Devices (CCD) by image-relaying structures separately. The errors between intersection points of two cross-talk images and centroid coordinates of actual beam are recorded automatically and sent to closed loop feedback control mechanism. Negative feedback keeps running until preset accuracy is reached. On the basis of above-mentioned design, the alignment optical path is built and the software is compiled, whereafter the experiment of double paths automatic alignment in electron pumped excimer laser amplifier is carried through. Meanwhile, the related influencing factors and the alignment precision are analyzed. Experimental results indicate that the alignment system can achieve the aiming direction of automatic aligning beams in short time. The analysis shows that the accuracy of alignment system is 0.63μrad and the beam maximum restoration error is 13.75μm. Furthermore, the bigger distance between the two cross-hairs, the higher precision of the system is. Therefore, the automatic alignment system has been used in angular multiplexing excimer Main Oscillation Power Amplification (MOPA) system and can satisfy the requirement of beam alignment precision on the whole.

Crisis route to chaos in semiconductor lasers subjected to external optical feedback

NASA Astrophysics Data System (ADS)

Wishon, Michael J.; Locquet, Alexandre; Chang, C. Y.; Choi, D.; Citrin, D. S.

2018-03-01

Semiconductor lasers subjected to optical feedback have been intensively used as archetypical testbeds for high-speed (sub-ns) and high-dimensional nonlinear dynamics. By simultaneously extracting all the dynamical variables, we demonstrate that for larger current, the commonly named "quasiperiodic" route is in fact based on mixed external-cavity solutions that lock the oscillation frequency of the intensity, voltage, and separation in optical frequency through a mechanism involving successive rejections along the unstable manifold of an antimode. We show that chaos emerges from a crisis resulting from the inability to maintain locking as the unstable manifold becomes inaccessible.

Demonstration of optical rogue waves using a laser diode emitting at 980  nm and a fiber Bragg grating.

PubMed

Lee, Min Won; Baladi, Fadwa; Burie, Jean-René; Bettiati, Mauro A; Boudrioua, Azzedine; Fischer, Alexis P A

2016-10-01

Rogue waves are observed for the first time, to the best of our knowledge, in a 980 nm laser diode subject to filtered optical feedback via a fiber Bragg grating. By counting the number of rogue waves in a fixed time window, a rogue wave map is established experimentally as a function of both the optical feedback ratio and the laser current. The comparison with low frequency fluctuations (LFFs) reveals that the rogue waves observed in our system are, in fact, LFF jump-ups.

Short educational programs in optical design and engineering

NASA Astrophysics Data System (ADS)

Voznesenskaya, Anna; Romanova, Galina; Bakholdin, Alexey; Tolstoba, Nadezhda; Ezhova, Kseniia

2016-09-01

Globalization and diversification of education in optical engineering causes a number of new phenomena in students' learning paths. Many students have an interest to get some courses in other universities, to study in international environment, to broaden not only professional skills but social links and see the sights as well etc. Participation in short educational programs (e.g. summer / winter schools, camps etc.) allows students from different universities to learn specific issues in their or in some neighbor field and also earn some ECTS for the transcript of records. ITMO University provides a variety of short educational programs in optical design and engineering oriented for different background level, such are: Introduction into optical engineering, Introduction into applied and computer optics, Optical system design, Image modeling and processing, Design of optical devices and components. Depending on students' educational background these programs are revised and adopted each time. Usually the short educational programs last 4 weeks and provide 4 ECTS. The short programs utilize a set of out-of date educational technologies like problem-based learning, case-study and distance-learning and evaluation. Practically, these technologies provide flexibility of the educational process and intensive growth of the learning outcomes. Students are satisfied with these programs very much. In their feedbacks they point a high level of practical significance, experienced teaching staff, scholarship program, excellent educational environment, as well as interesting social program and organizational support.

Quasi-monolithic tunable optical resonator

NASA Technical Reports Server (NTRS)

Arbore, Mark (Inventor); Tapos, Francisc (Inventor)

2003-01-01

An optical resonator has a piezoelectric element attached to a quasi-monolithic structure. The quasi-monolithic structure defines an optical path. Mirrors attached to the structure deflect light along the optical path. The piezoelectric element controllably strains the quasi-monolithic structure to change a length of the optical path by about 1 micron. A first feedback loop coupled to the piezoelectric element provides fine control over the cavity length. The resonator may include a thermally actuated spacer attached to the cavity and a mirror attached to the spacer. The thermally actuated spacer adjusts the cavity length by up to about 20 microns. A second feedback loop coupled to the sensor and heater provides a coarse control over the cavity length. An alternative embodiment provides a quasi-monolithic optical parametric oscillator (OPO). This embodiment includes a non-linear optical element within the resonator cavity along the optical path. Such an OPO configuration is broadly tunable and capable of mode-hop free operation for periods of 24 hours or more.

Design, development, and evaluation of an MRI-guided SMA spring-actuated neurosurgical robot

PubMed Central

Ho, Mingyen; Kim, Yeongjin; Cheng, Shing Shin; Gullapalli, Rao; Desai, Jaydev P.

2015-01-01

In this paper, we present our work on the development of a magnetic resonance imaging (MRI)-compatible Minimally Invasive Neurosurgical Intracranial Robot (MINIR) comprising of shape memory alloy (SMA) spring actuators and tendon-sheath mechanism. We present the detailed modeling and analysis along with experimental results of the characterization of SMA spring actuators. Furthermore, to demonstrate image-feedback control, we used the images obtained from a camera to control the motion of the robot so that eventually continuous MR images could be used in the future to control the robot motion. Since the image tracking algorithm may fail in some situations, we also developed a temperature feedback control scheme which served as a backup controller for the robot. Experimental results demonstrated that both image feedback and temperature feedback can be used to control the motion of MINIR. A series of MRI compatibility tests were performed on the robot and the experimental results demonstrated that the robot is MRI compatible and no significant visual image distortion was observed in the MR images during robot operation. PMID:26622075

A fast feedback method to design easy-molding freeform optical system with uniform illuminance and high light control efficiency.

PubMed

Hongtao, Li; Shichao, Chen; Yanjun, Han; Yi, Luo

2013-01-14

A feedback method combined with fitting technique based on variable separation mapping is proposed to design freeform optical systems for an extended LED source with prescribed illumination patterns, especially with uniform illuminance distribution. Feedback process performs well with extended sources, while fitting technique contributes not only to the decrease of pieces of sub-surfaces in discontinuous freeform lenses which may cause loss in manufacture, but also the reduction in the number of feedback iterations. It is proved that light control efficiency can be improved by 5%, while keeping a high uniformity of 82%, with only two feedback iterations and one fitting operation can improve. Furthermore, the polar angle θ and azimuthal angle φ is used to specify the light direction from the light source, and the (θ,φ)-(x,y) based mapping and feedback strategy makes sure that even few discontinuous sections along the equi-φ plane exist in the system, they are perpendicular to the base plane, making it eligible for manufacturing the surfaces using injection molding.

The Physics of Ultracold Sr2 Molecules: Optical Production and Precision Measurement

DTIC Science & Technology

2013-01-01

causing stimulated emission. The wavelength of the feedback light is determined by the angle of the feedback mirror . The zeroth order is the output from...with representative mirror , diffraction grating and diode housing (right). . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 2.14 Schematic of...of the feedback light is determined by the angle of the feedback mirror . The zeroth order is the output from the ECDL. . . . . . . . . . . . 23 2.15

External modes in quantum dot light emitting diode with filtered optical feedback

NASA Astrophysics Data System (ADS)

Al Husseini, Hussein B.; Al Naimee, Kais A.; Al-Khursan, Amin H.; Khedir, Ali. H.

2016-06-01

This research reports a theoretical investigation on the role of filtered optical feedback (FOF) in the quantum dot light emitting diode (QD-LED). The underlying dynamics is affected by a sidle node, which returns to an elliptical shape when the wetting layer (WL) is neglected. Both filter width and time delay change the appearance of different dynamics (chaotic and mixed mode oscillations, MMOs). The results agree with the experimental observations. Here, the fixed point analysis for QDs was done for the first time. For QD-LED with FOF, the system transits from the coherence collapse case in conventional optical feedback to a coherent case with a filtered mode in FOF. It was found that the WL washes out the modes which is an unexpected result. This may attributed to the longer capture time of WL compared with that between QD states. Thus, WL reduces the chaotic behavior.

External modes in quantum dot light emitting diode with filtered optical feedback

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al Husseini, Hussein B.; Department of Physics, College of Science, University of Baghdad, Al Jadiriyah, Baghdad; Al Naimee, Kais A.

2016-06-14

This research reports a theoretical investigation on the role of filtered optical feedback (FOF) in the quantum dot light emitting diode (QD-LED). The underlying dynamics is affected by a sidle node, which returns to an elliptical shape when the wetting layer (WL) is neglected. Both filter width and time delay change the appearance of different dynamics (chaotic and mixed mode oscillations, MMOs). The results agree with the experimental observations. Here, the fixed point analysis for QDs was done for the first time. For QD-LED with FOF, the system transits from the coherence collapse case in conventional optical feedback to amore » coherent case with a filtered mode in FOF. It was found that the WL washes out the modes which is an unexpected result. This may attributed to the longer capture time of WL compared with that between QD states. Thus, WL reduces the chaotic behavior.« less

Methods and apparatus for broadband frequency comb stabilization

DOEpatents

Cox, Jonathan A; Kaertner, Franz X

2015-03-17

Feedback loops can be used to shift and stabilize the carrier-envelope phase of a frequency comb from a mode-locked fibers laser or other optical source. Compared to other frequency shifting and stabilization techniques, feedback-based techniques provide a wideband closed-loop servo bandwidth without optical filtering, beam pointing errors, or group velocity dispersion. It also enables phase locking to a stable reference, such as a Ti:Sapphire laser, continuous-wave microwave or optical source, or self-referencing interferometer, e.g., to within 200 mrad rms from DC to 5 MHz. In addition, stabilized frequency combs can be coherently combined with other stable signals, including other stabilized frequency combs, to synthesize optical pulse trains with pulse durations of as little as a single optical cycle. Such a coherent combination can be achieved via orthogonal control, using balanced optical cross-correlation for timing stabilization and balanced homodyne detection for phase stabilization.

Real-time Graphics Processing Unit Based Fourier Domain Optical Coherence Tomography and Surgical Applications

NASA Astrophysics Data System (ADS)

Zhang, Kang

2011-12-01

In this dissertation, real-time Fourier domain optical coherence tomography (FD-OCT) capable of multi-dimensional micrometer-resolution imaging targeted specifically for microsurgical intervention applications was developed and studied. As a part of this work several ultra-high speed real-time FD-OCT imaging and sensing systems were proposed and developed. A real-time 4D (3D+time) OCT system platform using the graphics processing unit (GPU) to accelerate OCT signal processing, the imaging reconstruction, visualization, and volume rendering was developed. Several GPU based algorithms such as non-uniform fast Fourier transform (NUFFT), numerical dispersion compensation, and multi-GPU implementation were developed to improve the impulse response, SNR roll-off and stability of the system. Full-range complex-conjugate-free FD-OCT was also implemented on the GPU architecture to achieve doubled image range and improved SNR. These technologies overcome the imaging reconstruction and visualization bottlenecks widely exist in current ultra-high speed FD-OCT systems and open the way to interventional OCT imaging for applications in guided microsurgery. A hand-held common-path optical coherence tomography (CP-OCT) distance-sensor based microsurgical tool was developed and validated. Through real-time signal processing, edge detection and feed-back control, the tool was shown to be capable of track target surface and compensate motion. The micro-incision test using a phantom was performed using a CP-OCT-sensor integrated hand-held tool, which showed an incision error less than +/-5 microns, comparing to >100 microns error by free-hand incision. The CP-OCT distance sensor has also been utilized to enhance the accuracy and safety of optical nerve stimulation. Finally, several experiments were conducted to validate the system for surgical applications. One of them involved 4D OCT guided micro-manipulation using a phantom. Multiple volume renderings of one 3D data set were performed with different view angles to allow accurate monitoring of the micro-manipulation, and the user to clearly monitor tool-to-target spatial relation in real-time. The system was also validated by imaging multiple biological samples, such as human fingerprint, human cadaver head and small animals. Compared to conventional surgical microscopes, GPU-based real-time FD-OCT can provide the surgeons with a real-time comprehensive spatial view of the microsurgical region and accurate depth perception.

Real-Time Optical Biopsy of Colon Polyps With Narrow Band Imaging in Community Practice Does Not Yet Meet Key Thresholds for Clinical Decisions

PubMed Central

LADABAUM, URI; FIORITTO, ANN; MITANI, AYA; DESAI, MANISHA; KIM, JANE P.; REX, DOUGLAS K.; IMPERIALE, THOMAS; GUNARATNAM, NARESH

2017-01-01

BACKGROUND & AIMS Accurate optical analysis of colorectal polyps (optical biopsy) could prevent unnecessary polypectomies or allow a “resect and discard” strategy with surveillance intervals determined based on the results of the optical biopsy; this could be less expensive than histopathologic analysis of polyps. We prospectively evaluated real-time optical biopsy analysis of polyps with narrow band imaging (NBI) by community-based gastroenterologists. METHODS We first analyzed a computerized module to train gastroenterologists (N = 13) in optical biopsy skills using photographs of polyps. Then we evaluated a practice-based learning program for these gastroenterologists (n = 12) that included real-time optical analysis of polyps in vivo, comparison of optical biopsy predictions to histopathologic analysis, and ongoing feedback on performance. RESULTS Twelve of 13 subjects identified adenomas with >90% accuracy at the end of the computer study, and 3 of 12 subjects did so with accuracy ≥90% in the in vivo study. Learning curves showed considerable variation among batches of polyps. For diminutive rectosigmoid polyps assessed with high confidence at the end of the study, adenomas were identified with mean (95% confidence interval [CI]) accuracy, sensitivity, specificity, and negative predictive values of 81% (73%–89%), 85% (74%–96%), 78% (66%–92%), and 91% (86%–97%), respectively. The adjusted odds ratio for high confidence as a predictor of accuracy was 1.8 (95% CI, 1.3–2.5). The agreement between surveillance recommendations informed by high-confidence NBI analysis of diminutive polyps and results from histopathologic analysis of all polyps was 80% (95% CI, 77%–82%). CONCLUSIONS In an evaluation of real-time optical biopsy analysis of polyps with NBI, only 25% of gastroenterologists assessed polyps with ≥90% accuracy. The negative predictive value for identification of adenomas, but not the surveillance interval agreement, met the American Society for Gastrointestinal Endoscopy–recommended thresholds for optical biopsy. Better results in community practice must be achieved before NBI-based optical biopsy methods can be used routinely to evaluate polyps; ClinicalTrials.gov number, NCT01638091. PMID:23041328

Anisoplanatic image propagation along a slanted path under lower atmosphere phase turbulence in the presence of encrypted chaos

NASA Astrophysics Data System (ADS)

Chatterjee, Monish R.; Mohamed, Ali A.

2017-05-01

In recent research, anisoplanatic electromagnetic (EM) wave propagation along a slanted path in the presence of low atmosphere phase turbulence (modified von Karman spectrum or MVKS) has been investigated assuming a Hufnagel-Valley (HV) type structure parameter. Preliminary results indicate a strong dependence on the slant angle especially for long range transmission and relatively strong turbulence. The investigation was further divided into two regimes, viz. (a) one where the EM source consisted of a plane wave modulated with a digitized image, which is propagated along the turbulent path and recovered via demodulation at the receiver; and (b) transmit the plane wave without modulation along the turbulent path through an image transparency and a thin lens designed to gather the received image in the focal plane. In this paper, we reexamine the same problem (part (a) only) in the presence of a chaotic optical carrier where the chaos is generated in the feedback loop of an acousto-optic Bragg cell. The image information is encrypted within the chaos wave, and subsequently propagated along a similar slant path and identical turbulence conditions. The recovered image extracted via heterodyning from the received chaos is compared quantitatively (through image cross-correlations and mean-squared error measures) for the non-chaotic versus the chaotic approaches. Generally, "packaging" the information in chaos improves performance through turbulent propagation, and results are discussed from this perspective. Concurrently, we will also examine the effect of a non-encrypted plane EM wave propagation through a transparency-lens combination. These results are also presented with appropriate comparisons with the cases involving lensless transmission of imagery through corresponding turbulent and non-turbulent layers.

Lightweight uncooled TWS equipped with catadioptric optics and microscan mechanism

NASA Astrophysics Data System (ADS)

Bergeron, A.; Jerominek, H.; Doucet, M.; Lagacé, F.; Desnoyers, N.; Bernier, S.; Mercier, L.; Boucher, M.-A.; Jacob, M.; Alain, C.; Pope, T. D.; Laou, P.

2006-05-01

A rugged lightweight thermal weapon sight (TWS) prototype was developed at INO in collaboration with DRDC-Valcartier. This TWS model is based on uncooled bolometer technology, ultralight catadioptric optics, ruggedized mechanics and electronics, and extensive onboard processing capabilities. The TWS prototype operates in a single 8-12 μm infrared (IR) band. It is equipped with a unique lightweight athermalized catadioptric objective and a bolometric IR imager with an INO focal plane array (FPA). Microscan technology allows the use of a 160 x 120 pixel FPA with a pitch of 50 μm to achieve a 320 × 240 pixel resolution image thereby avoiding the size (larger optics) and cost (expensive IR optical components) penalties associated with the use of larger format arrays. The TWS is equipped with a miniature shutter for automatic offset calibration. Based on the operation of the FPA at 100 frames per second (fps), real-time imaging with 320 x 240 pixel resolution at 25 fps is available. This TWS is also equipped with a high resolution (857 x 600 pixels) OLED color microdisplay and an integrated wireless digital RF link. The sight has an adjustable and selectable electronic reticule or crosshair (five possible reticules) and a manual focus from 5 m to infinity standoff distance. Processing capabilities are added to introduce specific functionalities such as image inversion (black hot and white hot), image enhancement, and pixel smoothing. This TWS prototype is very lightweight (~ 1100 grams) and compact (volume of 93 cubic inches). It offers human size target detection at 800 m and recognition at 200 m (Johnson criteria). With 6 Li AA batteries, it operates continuously for 5 hours and 20 minutes at room temperature. It can operate over the temperature range of -30 °C to +40 °C and its housing is completely sealed. The TWS is adapted to weaver or Picatinny rail mounting. The overall design of the TWS prototype is based on feedbacks of users to achieve improved user-friendly (e.g. no pull-down menus and no electronic focusing) and ergonomic (e.g. locations of buttons) features.

Integrated optical sensor

DOEpatents

Watkins, Arthur D.; Smartt, Herschel B.; Taylor, Paul L.

1994-01-01

An integrated optical sensor for arc welding having multifunction feedback control. The sensor, comprising generally a CCD camera and diode laser, is positioned behind the arc torch for measuring weld pool position and width, standoff distance, and post-weld centerline cooling rate. Computer process information from this sensor is passed to a controlling computer for use in feedback control loops to aid in the control of the welding process. Weld pool position and width are used in a feedback loop, by the weld controller, to track the weld pool relative to the weld joint. Sensor standoff distance is used in a feedback loop to control the contact tip to base metal distance during the welding process. Cooling rate information is used to determine the final metallurgical state of the weld bead and heat affected zone, thereby controlling post-weld mechanical properties.

Integrated optical sensor

DOEpatents

Watkins, A.D.; Smartt, H.B.; Taylor, P.L.

1994-01-04

An integrated optical sensor for arc welding having multifunction feedback control is described. The sensor, comprising generally a CCD camera and diode laser, is positioned behind the arc torch for measuring weld pool position and width, standoff distance, and post-weld centerline cooling rate. Computer process information from this sensor is passed to a controlling computer for use in feedback control loops to aid in the control of the welding process. Weld pool position and width are used in a feedback loop, by the weld controller, to track the weld pool relative to the weld joint. Sensor standoff distance is used in a feedback loop to control the contact tip to base metal distance during the welding process. Cooling rate information is used to determine the final metallurgical state of the weld bead and heat affected zone, thereby controlling post-weld mechanical properties. 6 figures.

Vision Based Autonomous Robotic Control for Advanced Inspection and Repair

NASA Technical Reports Server (NTRS)

Wehner, Walter S.

2014-01-01

The advanced inspection system is an autonomous control and analysis system that improves the inspection and remediation operations for ground and surface systems. It uses optical imaging technology with intelligent computer vision algorithms to analyze physical features of the real-world environment to make decisions and learn from experience. The advanced inspection system plans to control a robotic manipulator arm, an unmanned ground vehicle and cameras remotely, automatically and autonomously. There are many computer vision, image processing and machine learning techniques available as open source for using vision as a sensory feedback in decision-making and autonomous robotic movement. My responsibilities for the advanced inspection system are to create a software architecture that integrates and provides a framework for all the different subsystem components; identify open-source algorithms and techniques; and integrate robot hardware.

Haptic feedback in OP:Sense - augmented reality in telemanipulated robotic surgery.

PubMed

Beyl, T; Nicolai, P; Mönnich, H; Raczkowksy, J; Wörn, H

2012-01-01

In current research, haptic feedback in robot assisted interventions plays an important role. However most approaches to haptic feedback only regard the mapping of the current forces at the surgical instrument to the haptic input devices, whereas surgeons demand a combination of medical imaging and telemanipulated robotic setups. In this paper we describe how this feature is integrated in our robotic research platform OP:Sense. The proposed method allows the automatic transfer of segmented imaging data to the haptic renderer and therefore allows enriching the haptic feedback with virtual fixtures based on imaging data. Anatomical structures are extracted from pre-operative generated medical images or virtual walls are defined by the surgeon inside the imaging data. Combining real forces with virtual fixtures can guide the surgeon to the regions of interest as well as helps to prevent the risk of damage to critical structures inside the patient. We believe that the combination of medical imaging and telemanipulation is a crucial step for the next generation of MIRS-systems.

Strong intensity variations of laser feedback interferometer caused by atmospheric turbulence

NASA Astrophysics Data System (ADS)

Sun, Yiyi; Li, Zhiping

2003-05-01

The significant variation of the laser output can be caused by feedback of a small part of laser beam, which is reflected or backscattered by a target at a long distance from laser source, into the laser cavity. This paper describes and analyzes theoretically and experimentally the influence of atmospheric turbulence on interference caused by laser feedback. The influence depends upon both the energy of feedback into the laser cavity and the strength of turbulence over a laser propagation path in the atmosphere. In the case of stronger energy of feedback and weak turbulence variance of fluctuation of the laser output can be enhanced by hundreds to thousands times. From our measurements and theoretical analysis it shows thatthese significant enhancements can result from the change of laser-cavity-modes which can be stimulated simultaneously and from beat oscillations between a variety of frequencies of laser modes. This also can result from optical chaos inside the laser resonator because a non-separable distorted external cavity can become a prerequisite for optical chaos.

Adaptive electron beam shaping using a photoemission gun and spatial light modulator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maxson, Jared; Lee, Hyeri; Bartnik, Adam C.

The need for precisely defined beam shapes in photoelectron sources has been well established. In this paper, we use a spatial light modulator and simple shaping algorithm to create arbitrary, detailed transverse laser shapes with high fidelity. We transmit this shaped laser to the photocathode of a high voltage dc gun. Using beam currents where space charge is negligible, and using an imaging solenoid and fluorescent viewscreen, we show that the resultant beam shape preserves these detailed features with similar fidelity. Next, instead of transmitting a shaped laser profile, we use an active feedback on the unshaped electron beam imagemore » to create equally accurate and detailed shapes. We demonstrate that this electron beam feedback has the added advantage of correcting for electron optical aberrations, yielding shapes without skew. The method may serve to provide precisely defined electron beams for low current target experiments, space-charge dominated beam commissioning, as well as for online adaptive correction of photocathode quantum efficiency degradation.« less

Adaptive electron beam shaping using a photoemission gun and spatial light modulator

DOE PAGES

Maxson, Jared; Lee, Hyeri; Bartnik, Adam C.; ...

2015-02-01

The need for precisely defined beam shapes in photoelectron sources has been well established. In this paper, we use a spatial light modulator and simple shaping algorithm to create arbitrary, detailed transverse laser shapes with high fidelity. We transmit this shaped laser to the photocathode of a high voltage dc gun. Using beam currents where space charge is negligible, and using an imaging solenoid and fluorescent viewscreen, we show that the resultant beam shape preserves these detailed features with similar fidelity. Next, instead of transmitting a shaped laser profile, we use an active feedback on the unshaped electron beam imagemore » to create equally accurate and detailed shapes. We demonstrate that this electron beam feedback has the added advantage of correcting for electron optical aberrations, yielding shapes without skew. The method may serve to provide precisely defined electron beams for low current target experiments, space-charge dominated beam commissioning, as well as for online adaptive correction of photocathode quantum efficiency degradation.« less

Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster

PubMed Central

Mendes, César S; Bartos, Imre; Akay, Turgay; Márka, Szabolcs; Mann, Richard S

2013-01-01

Coordinated walking in vertebrates and multi-legged invertebrates such as Drosophila melanogaster requires a complex neural network coupled to sensory feedback. An understanding of this network will benefit from systems such as Drosophila that have the ability to genetically manipulate neural activities. However, the fly's small size makes it challenging to analyze walking in this system. In order to overcome this limitation, we developed an optical method coupled with high-speed imaging that allows the tracking and quantification of gait parameters in freely walking flies with high temporal and spatial resolution. Using this method, we present a comprehensive description of many locomotion parameters, such as gait, tarsal positioning, and intersegmental and left-right coordination for wild type fruit flies. Surprisingly, we find that inactivation of sensory neurons in the fly's legs, to block proprioceptive feedback, led to deficient step precision, but interleg coordination and the ability to execute a tripod gait were unaffected. DOI: http://dx.doi.org/10.7554/eLife.00231.001 PMID:23326642

DOE Center of Excellence in Medical Laser Applications. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacques, S.L.

1998-01-01

An engineering network of collaborating medical laser laboratories are developing laser and optical technologies for medical diagnosis and therapy and are translating the engineering into medical centers in Portland, OR, Houston, TX, and Galveston, TX. The Center includes the University of Texas M.D. Anderson Cancer Center, the University of Texas-Austin, Texas A and M University, Rice University, the University Texas Medical Branch-Galveston, Oregon Medical Laser Center (Providence St. Vincent Medical Center, Oregon Health Sciences University, and Oregon Graduate Institute, Portland, OR), and the University of Oregon. Diagnostics include reflectance, fluorescence, Raman IR, laser photoacoustics, optical coherence tomography, and several newmore » video techniques for spectroscopy and imaging. Therapies include photocoagulation therapy, laser welding, pulsed laser ablation, and light-activated chemotherapy of cancer (photodynamic therapy, or PDT). Medical applications reaching the clinic include optical monitoring of hyperbilirubinemia in newborns, fluorescence detection of cervical dysplasia, laser thrombolysis of blood clots in heart attack and brain stroke, photothermal coagulation of benign prostate hyperplasia, and PDT for both veterinary and human cancer. New technologies include laser optoacoustic imaging of breast tumors and hemorrhage in head trauma and brain stroke, quality control monitoring of dosimetry during PDT for esophageal and lung cancer, polarization video reflectometry of skin cancer, laser welding of artificial tissue replacements, and feedback control of laser welding.« less

DOE Center of Excellence in Medical Laser Applications. Final report, December 1, 1994--November 30, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacques, S.L.

1998-01-01

An engineering network of collaborating medical laser laboratories are developing laser and optical technologies for medical diagnosis and therapy and are translating the engineering into medical centers in Portland OR, Houston TX, and Galveston TX. The Center includes the University of Texas M.D. Anderson Cancer Center, the University of Texas-Austin, Texas A and M University, Rice University, the University Texas Medical Branch-Galveston, Oregon Medical Laser Center (Providence St. Vincent Medical Center, Oregon Health Sciences University, and Oregon Graduate Institute, Portland, OR), and the University of Oregon. Diagnostics include reflectance, fluorescence, Raman IR, laser photoacoustics, optical coherence tomography, and several newmore » video techniques for spectroscopy and imaging. Therapies include photocoagulation therapy, laser welding, pulsed laser ablation, and light-activated chemotherapy of cancer (photodynamic therapy, or PDT). Medical applications reaching the clinic include optical monitoring of hyperbilirubinemia in newborns, fluorescence detection of cervical dysplasia, laser thrombolysis of blood clots in heart attack and brain stroke, photothermal coagulant of benign prostate hyperplasia, and PDT for both veterinary and human cancer. New technologies include laser optoacoustic imaging of breast tumors and hemorrhage in head trauma and brain stroke, quality control monitoring of dosimetry during PDT for esophageal and lung cancer, polarization video reflectometry of skin cancer, laser welding of artificial tissue replacements, and feedback control of laser welding.« less

Compact light-emitting-diode sun photometer for atmospheric optical depth measurements.

PubMed

Acharya, Y B; Jayaraman, A; Ramachandran, S; Subbaraya, B H

1995-03-01

A new compact light-emitting diode (LED) sun photometer, in which a LED is used as a spectrally selective photodetector as well as a nonlinear feedback element in the operational amplifier, has been developed. The output voltage that is proportional to the logarithm of the incident solar intensity permits the direct measurement of atmospheric optical depths in selected spectral bands. Measurements made over Ahmedabad, India, show good agreement, within a few percent, of optical depths derived with a LED as a photodetector in a linear mode and with a LED as both a photodetector and a feedback element in an operational amplifier in log mode. The optical depths are also found to compare well with those obtained simultaneously with a conventional filter photometer.

The Dependence of Cloud Property Trend Detection on Absolute Calibration Accuracy of Passive Satellite Sensors

NASA Astrophysics Data System (ADS)

Shea, Y.; Wielicki, B. A.; Sun-Mack, S.; Minnis, P.; Zelinka, M. D.

2016-12-01

Detecting trends in climate variables on global, decadal scales requires highly accurate, stable measurements and retrieval algorithms. Trend uncertainty depends on its magnitude, natural variability, and instrument and retrieval algorithm accuracy and stability. We applied a climate accuracy framework to quantify the impact of absolute calibration on cloud property trend uncertainty. The cloud properties studied were cloud fraction, effective temperature, optical thickness, and effective radius retrieved using the Clouds and the Earth's Radiant Energy System (CERES) Cloud Property Retrieval System, which uses Moderate-resolution Imaging Spectroradiometer measurements (MODIS). Modeling experiments from the fifth phase of the Climate Model Intercomparison Project (CMIP5) agree that net cloud feedback is likely positive but disagree regarding its magnitude, mainly due to uncertainty in shortwave cloud feedback. With the climate accuracy framework we determined the time to detect trends for instruments with various calibration accuracies. We estimated a relationship between cloud property trend uncertainty, cloud feedback, and Equilibrium Climate Sensitivity and also between effective radius trend uncertainty and aerosol indirect effect trends. The direct relationship between instrument accuracy requirements and climate model output provides the level of instrument absolute accuracy needed to reduce climate model projection uncertainty. Different cloud types have varied radiative impacts on the climate system depending on several attributes, such as their thermodynamic phase, altitude, and optical thickness. Therefore, we also conducted these studies by cloud types for a clearer understanding of instrument accuracy requirements needed to detect changes in their cloud properties. Combining this information with the radiative impact of different cloud types helps to prioritize among requirements for future satellite sensors and understanding the climate detection capabilities of existing sensors.

Opto-acoustic transducer for medical applications

DOEpatents

Benett, William; Celliers, Peter; Da Silva, Luiz; Glinsky, Michael; London, Richard; Maitland, Duncan; Matthews, Dennis; Krulevich, Peter; Lee, Abraham

2002-01-01

This invention is an optically activated transducer for generating acoustic vibrations in a biological medium. The transducer is located at the end of a fiber optic which may be located within a catheter. Energy for operating the transducer is provided optically by laser light transmitted through the fiber optic to the transducer. Pulsed laser light is absorbed in the working fluid of the transducer to generate a thermal pressure and consequent adiabatic expansion of the transducer head such that it does work against the ambient medium. The transducer returns to its original state by a process of thermal cooling. The motion of the transducer within the ambient medium couples acoustic energy into the medium. By pulsing the laser at a high repetition rate (which may vary from CW to 100 kHz) an ultrasonic radiation field can be established locally in the medium. This method of producing ultrasonic vibrations can be used in vivo for the treatment of stroke-related conditions in humans, particularly for dissolving thrombus. The catheter may also incorporate anti-thrombolytic drug treatments as an adjunct therapy and it may be operated in conjunction with ultrasonic detection equipment for imaging and feedback control.

Opto-acoustic transducer for medical applications

DOEpatents

Benett, William; Celliers, Peter; Da Silva, Luiz; Glinsky, Michael; London, Richard; Maitland, Duncan; Matthews, Dennis; Krulevich, Peter; Lee, Abraham

1999-01-01

This invention is an optically activated transducer for generating acoustic vibrations in a biological medium. The transducer is located at the end of a fiber optic which may be located within a catheter. Energy for operating the transducer is provided optically by laser light transmitted through the fiber optic to the transducer. Pulsed laser light is absorbed in the working fluid of the transducer to generate a thermal pressure and consequent adiabatic expansion of the transducer head such that it does work against the ambient medium. The transducer returns to its original state by a process of thermal cooling. The motion of the transducer within the ambient medium couples acoustic energy into the medium. By pulsing the laser at a high repetition rate (which may vary from CW to 100 kHz) an ultrasonic radiation field can be established locally in the medium. This method of producing ultrasonic vibrations can be used in vivo for the treatment of stroke-related conditions in humans, particularly for dissolving thrombus. The catheter may also incorporate anti-thrombolytic drug treatments as an adjunct therapy and it may be operated in conjunction with ultrasonic detection equipment for imaging and feedback control.

Opto-acoustic transducer for medical applications

DOEpatents

Benett, W.; Celliers, P.; Da Silva, L.; Glinsky, M.; London, R.; Maitland, D.; Matthews, D.; Krulevich, P.; Lee, A.

1999-08-31

This invention is an optically activated transducer for generating acoustic vibrations in a biological medium. The transducer is located at the end of a fiber optic which may be located within a catheter. Energy for operating the transducer is provided optically by laser light transmitted through the fiber optic to the transducer. Pulsed laser light is absorbed in the working fluid of the transducer to generate a thermal pressure and consequent adiabatic expansion of the transducer head such that it does work against the ambient medium. The transducer returns to its original state by a process of thermal cooling. The motion of the transducer within the ambient medium couples acoustic energy into the medium. By pulsing the laser at a high repetition rate (which may vary from CW to 100 kHz) an ultrasonic radiation field can be established locally in the medium. This method of producing ultrasonic vibrations can be used in vivo for the treatment of stroke-related conditions in humans, particularly for dissolving thrombus. The catheter may also incorporate anti-thrombolytic drug treatments as an adjunct therapy and it may be operated in conjunction with ultrasonic detection equipment for imaging and feedback control. 7 figs.

A near-field scanning microwave microscope for characterization of inhomogeneous photovoltaics.

PubMed

Weber, J C; Schlager, J B; Sanford, N A; Imtiaz, A; Wallis, T M; Mansfield, L M; Coakley, K J; Bertness, K A; Kabos, P; Bright, V M

2012-08-01

We present a near-field scanning microwave microscope (NSMM) that has been configured for imaging photovoltaic samples. Our system incorporates a Pt-Ir tip inserted into an open-ended coaxial cable to form a weakly coupled resonator, allowing the microwave reflection S(11) signal to be measured across a sample over a frequency range of 1 GHz - 5 GHz. A phase-tuning circuit increased impedance-measurement sensitivity by allowing for tuning of the S(11) minimum down to -78 dBm. A bias-T and preamplifier enabled simultaneous, non-contact measurement of the DC tip-sample current, and a tuning fork feedback system provided simultaneous topographic data. Light-free tuning fork feedback provided characterization of photovoltaic samples both in the dark and under illumination at 405 nm. NSMM measurements were obtained on an inhomogeneous, third-generation Cu(In,Ga)Se(2) (CIGS) sample. The S(11) and DC current features were found to spatially broaden around grain boundaries with the sample under illumination. The broadening is attributed to optically generated charge that becomes trapped and changes the local depletion of the grain boundaries, thereby modifying the local capacitance. Imaging provided by the NSMM offers a new RF methodology to resolve and characterize nanoscale electrical features in photovoltaic materials and devices.

Is Linear Displacement Information Or Angular Displacement Information Used During The Adaptation of Pointing Responses To An Optically Shifted Image?

NASA Technical Reports Server (NTRS)

Bautista, Abigail B.

1994-01-01

Twenty-four observers looked through a pair of 20 diopter wedge prisms and pointed to an image of a target which was displaced vertically from eye level by 6 cm at a distance of 30 cm. Observers pointed 40 times, using only their right hand, and received error-corrective feedback upon termination of each pointing response (terminal visual feedback). At three testing distances, 20, 30, and 40 cm, ten pre-exposure and ten post-exposure pointing responses were recorded for each hand as observers reached to a mirror-viewed target located at eye level. The difference between pre- and post-exposure pointing response (adaptive shift) was compared for both Exposed and Unexposed hands across all three testing distances. The data were assessed according to the results predicted by two alternative models for processing spatial-information: one using angular displacement information and another using linear displacement information. The angular model of spatial mapping best predicted the observer's pointing response for the Exposed hand. Although the angular adaptive shift did not change significantly as a function of distance (F(2,44) = 1.12, n.s.), the linear adaptive shift increased significantly over the three testing distances 02 44) = 4.90 p less than 0.01).

A bio-inspired flying robot sheds light on insect piloting abilities.

PubMed

Franceschini, Nicolas; Ruffier, Franck; Serres, Julien

2007-02-20

When insects are flying forward, the image of the ground sweeps backward across their ventral viewfield and forms an "optic flow," which depends on both the groundspeed and the groundheight. To explain how these animals manage to avoid the ground by using this visual motion cue, we suggest that insect navigation hinges on a visual-feedback loop we have called the optic-flow regulator, which controls the vertical lift. To test this idea, we built a micro-helicopter equipped with an optic-flow regulator and a bio-inspired optic-flow sensor. This fly-by-sight micro-robot can perform exacting tasks such as take-off, level flight, and landing. Our control scheme accounts for many hitherto unexplained findings published during the last 70 years on insects' visually guided performances; for example, it accounts for the fact that honeybees descend in a headwind, land with a constant slope, and drown when travelling over mirror-smooth water. Our control scheme explains how insects manage to fly safely without any of the instruments used onboard aircraft to measure the groundheight, groundspeed, and descent speed. An optic-flow regulator is quite simple in terms of its neural implementation and just as appropriate for insects as it would be for aircraft.

Feedback control for manipulating magnetization in spin-exchange optical pumping system

NASA Astrophysics Data System (ADS)

Zhang, Ke; Li, Jun; Jiang, Min; Zhao, Nan; Peng, XinHua

2018-08-01

Control of magnetization plays an important role in the scientific and technological field of manipulating spin systems. In this work, we study the problem of manipulating nuclear magnetization in the spin-exchange optical pumping system, including accelerating the recovery of nuclear polarization and fixing it on a specific desired state. A real-time feedback control strategy is exploited here. We have also done some numerical simulations, with the results clearly demonstrating the effectiveness of our method, that the nuclear magnetization is able to be driven towards the equilibrium state at a much faster speed and also can be stabilized to a target state. We expect that our feedback control method can find applications in gyro experiments.

Real time imaging of peripheral nerve vasculature using optical coherence angiography

NASA Astrophysics Data System (ADS)

Vasudevan, Srikanth; Kumsa, Doe; Takmakov, Pavel; Welle, Cristin G.; Hammer, Daniel X.

2016-03-01

The peripheral nervous system (PNS) carries bidirectional information between the central nervous system and distal organs. PNS stimulation has been widely used in medical devices for therapeutic indications, such as bladder control and seizure cessation. Investigational uses of PNS stimulation include providing sensory feedback for improved control of prosthetic limbs. While nerve safety has been well documented for stimulation parameters used in marketed devices, novel PNS stimulation devices may require alternative stimulation paradigms to achieve maximum therapeutic benefit. Improved testing paradigms to assess the safety of stimulation will expedite the development process for novel PNS stimulation devices. The objective of this research is to assess peripheral nerve vascular changes in real-time with optical coherence angiography (OCA). A 1300-nm OCA system was used to image vasculature changes in the rat sciatic nerve in the region around a surface contacting single electrode. Nerves and vasculature were imaged without stimulation for 180 minutes to quantify resting blood vessel diameter. Walking track analysis was used to assess motor function before and 6 days following experiments. There was no significant change in vessel diameter between baseline and other time points in all animals. Motor function tests indicated the experiments did not impair functionality. We also evaluated the capabilities to image the nerve during electrical stimulation in a pilot study. Combining OCA with established nerve assessment methods can be used to study the effects of electrical stimulation safety on neural and vascular tissue in the periphery.

Distinguishing tracheal and esophageal tissues with hyperspectral imaging and fiber-optic sensing

NASA Astrophysics Data System (ADS)

Nawn, Corinne D.; Souhan, Brian E.; Carter, Robert, III; Kneapler, Caitlin; Fell, Nicholas; Ye, Jing Yong

2016-11-01

During emergency medical situations, where the patient has an obstructed airway or necessitates respiratory support, endotracheal intubation (ETI) is the medical technique of placing a tube into the trachea in order to facilitate adequate ventilation of the lungs. Complications during ETI, such as repeated attempts, failed intubation, or accidental intubation of the esophagus, can lead to severe consequences or ultimately death. Consequently, a need exists for a feedback mechanism to aid providers in performing successful ETI. Our study examined the spectral reflectance properties of the tracheal and esophageal tissue to determine whether a unique spectral profile exists for either tissue for the purpose of detection. The study began by using a hyperspectral camera to image excised pig tissue samples exposed to white and UV light in order to capture the spectral reflectance properties with high fidelity. After identifying a unique spectral characteristic of the trachea that significantly differed from esophageal tissue, a follow-up investigation used a fiber optic probe to confirm the detectability and consistency of the different reflectance characteristics in a pig model. Our results characterize the unique and consistent spectral reflectance characteristic of tracheal tissue, thereby providing foundational support for exploiting spectral properties to detect the trachea during medical procedures.

Free-standing membrane polymer laser on the end of an optical fiber

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhai, Tianrui, E-mail: trzhai@bjut.edu.cn, E-mail: zhangxinping@bjut.edu.cn; Li, Songtao; Hu, Yujie

2016-01-25

One- and two-dimensional distributed feedback cavities were constructed on free-standing polymer membranes using spin-coating and lift-off techniques. Low threshold lasing was generated through feedback amplification when the 290-nm membrane device was optically pumped, which was attributed to the strong confinement mechanism provided by the active waveguide layer without a substrate. The free-standing membrane polymer laser is flexible and can be transplanted. Single- and dual-wavelength fiber lasers were achieved by directly attaching the membrane polymer laser on the optical fiber end face. This technique provides potential to fabricate polymer lasers on surfaces with arbitrary shapes.

Conjunctive patches subspace learning with side information for collaborative image retrieval.

PubMed

Zhang, Lining; Wang, Lipo; Lin, Weisi

2012-08-01

Content-Based Image Retrieval (CBIR) has attracted substantial attention during the past few years for its potential practical applications to image management. A variety of Relevance Feedback (RF) schemes have been designed to bridge the semantic gap between the low-level visual features and the high-level semantic concepts for an image retrieval task. Various Collaborative Image Retrieval (CIR) schemes aim to utilize the user historical feedback log data with similar and dissimilar pairwise constraints to improve the performance of a CBIR system. However, existing subspace learning approaches with explicit label information cannot be applied for a CIR task, although the subspace learning techniques play a key role in various computer vision tasks, e.g., face recognition and image classification. In this paper, we propose a novel subspace learning framework, i.e., Conjunctive Patches Subspace Learning (CPSL) with side information, for learning an effective semantic subspace by exploiting the user historical feedback log data for a CIR task. The CPSL can effectively integrate the discriminative information of labeled log images, the geometrical information of labeled log images and the weakly similar information of unlabeled images together to learn a reliable subspace. We formally formulate this problem into a constrained optimization problem and then present a new subspace learning technique to exploit the user historical feedback log data. Extensive experiments on both synthetic data sets and a real-world image database demonstrate the effectiveness of the proposed scheme in improving the performance of a CBIR system by exploiting the user historical feedback log data.

A robotized six degree of freedom stage for optical microscopy

NASA Astrophysics Data System (ADS)

Avramov, M. Z.; Ivanov, I.; Pavlov, V.; Zaharieva, K.

2013-04-01

This work represents an investigation of the possibility to use a hexapod system for optical microscopy investigation and measurements. An appropriate hexapod stage has been developed. The stage has been calibrated and used for several different optical microscopy applications. The construction of the stage is based on the classic Stewart platform and thus represents a parallel robot with 6 degree of freedom. Appropriate software is controlling the transformation of the 3 position coordinates of the moving plate and the 3 Euler angles in position velocities and accelerations of the plate motion. An embedded microcontroller is implementing the motion plan and the PID controller regulating the kinematics. By difference to the available in the market hexapods the proposed solution is with lower precision but is significantly cheaper and simple to maintain. The repeatability obtained with current implementation is 0,05 mm and 0,001 rad. A specialized DSP based video processing engine is used for both feedback computation and application specific image processing in real-time. To verify the concept some applications has been developed for specific tasks and has been used for specific measurements.

The Raptor Real-Time Processing Architecture

NASA Astrophysics Data System (ADS)

Galassi, M.; Starr, D.; Wozniak, P.; Brozdin, K.

The primary goal of Raptor is ambitious: to identify interesting optical transients from very wide field of view telescopes in real time, and then to quickly point the higher resolution Raptor ``fovea'' cameras and spectrometer to the location of the optical transient. The most interesting of Raptor's many applications is the real-time search for orphan optical counterparts of Gamma Ray Bursts. The sequence of steps (data acquisition, basic calibration, source extraction, astrometry, relative photometry, the smarts of transient identification and elimination of false positives, telescope pointing feedback, etc.) is implemented with a ``component'' approach. All basic elements of the pipeline functionality have been written from scratch or adapted (as in the case of SExtractor for source extraction) to form a consistent modern API operating on memory resident images and source lists. The result is a pipeline which meets our real-time requirements and which can easily operate as a monolithic or distributed processing system. Finally, the Raptor architecture is entirely based on free software (sometimes referred to as ``open source'' software). In this paper we also discuss the interplay between various free software technologies in this type of astronomical problem.

Raptor -- Mining the Sky in Real Time

NASA Astrophysics Data System (ADS)

Galassi, M.; Borozdin, K.; Casperson, D.; McGowan, K.; Starr, D.; White, R.; Wozniak, P.; Wren, J.

2004-06-01

The primary goal of Raptor is ambitious: to identify interesting optical transients from very wide field of view telescopes in real time, and then to quickly point the higher resolution Raptor ``fovea'' cameras and spectrometer to the location of the optical transient. The most interesting of Raptor's many applications is the real-time search for orphan optical counterparts of Gamma Ray Bursts. The sequence of steps (data acquisition, basic calibration, source extraction, astrometry, relative photometry, the smarts of transient identification and elimination of false positives, telescope pointing feedback...) is implemented with a ``component'' aproach. All basic elements of the pipeline functionality have been written from scratch or adapted (as in the case of SExtractor for source extraction) to form a consistent modern API operating on memory resident images and source lists. The result is a pipeline which meets our real-time requirements and which can easily operate as a monolithic or distributed processing system. Finally: the Raptor architecture is entirely based on free software (sometimes referred to as "open source" software). In this paper we also discuss the interplay between various free software technologies in this type of astronomical problem.

High-resolution non-destructive three-dimensional imaging of integrated circuits

NASA Astrophysics Data System (ADS)

Holler, Mirko; Guizar-Sicairos, Manuel; Tsai, Esther H. R.; Dinapoli, Roberto; Müller, Elisabeth; Bunk, Oliver; Raabe, Jörg; Aeppli, Gabriel

2017-03-01

Modern nanoelectronics has advanced to a point at which it is impossible to image entire devices and their interconnections non-destructively because of their small feature sizes and the complex three-dimensional structures resulting from their integration on a chip. This metrology gap implies a lack of direct feedback between design and manufacturing processes, and hampers quality control during production, shipment and use. Here we demonstrate that X-ray ptychography—a high-resolution coherent diffractive imaging technique—can create three-dimensional images of integrated circuits of known and unknown designs with a lateral resolution in all directions down to 14.6 nanometres. We obtained detailed device geometries and corresponding elemental maps, and show how the devices are integrated with each other to form the chip. Our experiments represent a major advance in chip inspection and reverse engineering over the traditional destructive electron microscopy and ion milling techniques. Foreseeable developments in X-ray sources, optics and detectors, as well as adoption of an instrument geometry optimized for planar rather than cylindrical samples, could lead to a thousand-fold increase in efficiency, with concomitant reductions in scan times and voxel sizes.

High-resolution non-destructive three-dimensional imaging of integrated circuits.

PubMed

Holler, Mirko; Guizar-Sicairos, Manuel; Tsai, Esther H R; Dinapoli, Roberto; Müller, Elisabeth; Bunk, Oliver; Raabe, Jörg; Aeppli, Gabriel

2017-03-15

Modern nanoelectronics has advanced to a point at which it is impossible to image entire devices and their interconnections non-destructively because of their small feature sizes and the complex three-dimensional structures resulting from their integration on a chip. This metrology gap implies a lack of direct feedback between design and manufacturing processes, and hampers quality control during production, shipment and use. Here we demonstrate that X-ray ptychography-a high-resolution coherent diffractive imaging technique-can create three-dimensional images of integrated circuits of known and unknown designs with a lateral resolution in all directions down to 14.6 nanometres. We obtained detailed device geometries and corresponding elemental maps, and show how the devices are integrated with each other to form the chip. Our experiments represent a major advance in chip inspection and reverse engineering over the traditional destructive electron microscopy and ion milling techniques. Foreseeable developments in X-ray sources, optics and detectors, as well as adoption of an instrument geometry optimized for planar rather than cylindrical samples, could lead to a thousand-fold increase in efficiency, with concomitant reductions in scan times and voxel sizes.

Estimating nanoparticle optical absorption with magnetic resonance temperature imaging and bioheat transfer simulation.

PubMed

MacLellan, Christopher J; Fuentes, David; Elliott, Andrew M; Schwartz, Jon; Hazle, John D; Stafford, R Jason

2014-02-01

Optically activated nanoparticle-mediated heating for thermal therapy applications is an area of intense research. The ability to characterise the spatio-temporal heating potential of these particles for use in modelling under various exposure conditions can aid in the exploration of new approaches for therapy as well as more quantitative prospective approaches to treatment planning. The purpose of this research was to investigate an inverse solution to the heat equation using magnetic resonance temperature imaging (MRTI) feedback, for providing optical characterisation of two types of nanoparticles (gold-silica nanoshells and gold nanorods). The optical absorption of homogeneous nanoparticle-agar mixtures was measured during exposure to an 808 nm laser using real-time MRTI. A coupled finite element solution of heat transfer was registered with the data and used to solve the inverse problem. The L2 norm of the difference between the temperature increase in the model and MRTI was minimised using a pattern search algorithm by varying the absorption coefficient of the mixture. Absorption fractions were within 10% of literature values for similar nanoparticles. Comparison of temporal and spatial profiles demonstrated good qualitative agreement between the model and the MRTI. The weighted root mean square error was <1.5 σMRTI and the average Dice similarity coefficient for ΔT = 5 °C isotherms was >0.9 over the measured time interval. This research demonstrates the feasibility of using an indirect method for making minimally invasive estimates of nanoparticle absorption that might be expanded to analyse a variety of geometries and particles of interest.

Parity-time–symmetric optoelectronic oscillator

PubMed Central

2018-01-01

An optoelectronic oscillator (OEO) is a hybrid microwave and photonic system incorporating an amplified positive feedback loop to enable microwave oscillation to generate a high-frequency and low–phase noise microwave signal. The low phase noise is ensured by the high Q factor of the feedback loop enabled by the use of a long and low-loss optical fiber. However, an OEO with a long fiber loop would have a small free spectral range, leading to a large number of closely spaced oscillation modes. To ensure single-mode oscillation, an ultranarrowband optical filter must be used, but such an optical filter is hard to implement and the stability is poor. Here, we use a novel concept to achieve single-mode oscillation without using an ultranarrowband optical filter. The single-mode operation is achieved based on parity-time (PT) symmetry by using two identical feedback loops, with one having a gain and the other having a loss of the same magnitude. The operation is analyzed theoretically and verified by an experiment. Stable single-mode oscillation at an ultralow phase noise is achieved without the use of an ultranarrowband optical filter. The use of PT symmetry in an OEO overcomes the long-existing mode-selection challenge that would greatly simplify the implementation of OEOs for ultralow–phase noise microwave generation. PMID:29888325

Stable CW Single Frequency Operation of Fabry-Perot Laser Diodes by Self-Injection Phase Locking

NASA Technical Reports Server (NTRS)

Duerksen, Gary L.; Krainak, Michael A.

1999-01-01

Previously, single-frequency semiconductor laser operation using fiber Bragg gratings has been achieved by tWo methods: 1) use of the FBG as the output coupler for an anti-reflection-coated semiconductor gain element'; 2) pulsed operation of a gain-switched Fabry-Perot laser diode with FBG-optical and RF-electrical feedback'. Here, we demonstrate CW single frequency operation from a non-AR coated Fabry-Perot laser diode using only FBG optical feedback.

Stable CW Single-Frequency Operation of Fabry-Perot Laser Diodes by Self-Injection Phase Locking

NASA Technical Reports Server (NTRS)

Duerksen, Gary L.; Krainak, Michael A.

1998-01-01

Previously, single-frequency semiconductor laser operation using fiber Bragg gratings (FBG) has been achieved by two methods: (1) use of the FBG as the output coupler for an anti-reflection-coated semiconductor gain element; (2) pulsed operation of a gain-switched Fabry-Perot laser diode with FBG-optical and RF-electrical feedback. Here, we demonstrate CW single frequency operation from a non-AR coated Fabry-Perot laser diode using only FBG optical feedback.

Maximizing the security of chaotic optical communications.

PubMed

Hou, T T; Yi, L L; Yang, X L; Ke, J X; Hu, Y; Yang, Q; Zhou, P; Hu, W S

2016-10-03

The practical application of chaotic optical communications has been limited by two aspects: the difficulty in concealing the time delay - a critical security parameter in feedback chaotic systems, and the difficulty of significantly enlarging the key space without complicating the implementation. Here we propose an architecture to break the above limits. By introducing a frequency-dependent group delay module with frequency tuning resolution of 1 MHz into the chaotic feedback loop, we demonstrate excellent time delay concealment effect, and an additional huge key space of 10⁴⁸ can be achieved at the same time. The effectiveness is proved by both numerical simulation and experiment. Besides, the proposed scheme is compatible with the existing commercial optical communication systems, thus pave the way for high-speed secure optical communications.

Use of a compact fiber optic spectrometer for spectral feedback during the laser ablation of dental hard tissues and restorative materials

NASA Astrophysics Data System (ADS)

Cheng, Joyce Y.; Fan, Kenneth; Fried, Daniel

2006-02-01

One perceived disadvantage of caries removal using lasers is the loss of the tactile feedback associated with the handpiece. However, alternative methods of acoustic and optical feedback become available with the laser that can be exploited to provide information about the chemical composition of the material ablated, the ablation efficiency and rate, the depth of the incision, and the surface and plume temperature during ablation. Such information can be used to increase the selectivity of ablation, avoid peripheral thermal damage and excessive heat deposition in the tooth, and provide a mechanism of robotic automation. The objective of this study was to test the hypothesis that a compact fiberoptic spectrometer could be used to differentiate between the ablation of sound and carious enamel and dentin and between dental hard tissues and composite. Sound and carious tooth surfaces along with composite restorative materials were scanned with λ=0.355, 2.79 and 9.3 μm laser pulses at irradiation intensities ranging from 0.5-100 J/cm2 and spectra were acquired from λ=250-900-nm using a compact fiber-optic spectrometer. Emission spectra varied markedly with the laser wavelength and pulse duration. Optical feedback was not successful in differentiating between sound and carious enamel and dentin even with the addition of various chromophores to carious lesion areas. However, the spectral feedback was successfully used to differentiate between composites and sound enamel and dentin enabling the selective removal of composite from tooth surfaces using a computer controlled λ=9.3-μm pulsed CO II laser and scanning system.

Dynamic imperfections and optimized feedback design in the Compact Linear Collider main linac

NASA Astrophysics Data System (ADS)

Eliasson, Peder

2008-05-01

The Compact Linear Collider (CLIC) main linac is sensitive to dynamic imperfections such as element jitter, injected beam jitter, and ground motion. These effects cause emittance growth that, in case of ground motion, has to be counteracted by a trajectory feedback system. The feedback system itself will, due to jitter effects and imperfect beam position monitors (BPMs), indirectly cause emittance growth. Fast and accurate simulations of both the direct and indirect effects are desirable, but due to the many elements of the CLIC main linac, simulations may become very time consuming. In this paper, an efficient way of simulating linear (or nearly linear) dynamic effects is described. The method is also shown to facilitate the analytic determination of emittance growth caused by the different dynamic imperfections while using a trajectory feedback system. Emittance growth expressions are derived for quadrupole, accelerating structure, and beam jitter, for ground motion, and for noise in the feedback BPMs. Finally, it is shown how the method can be used to design a feedback system that is optimized for the optics of the machine and the ground motion spectrum of the particular site. This feedback system gives an emittance growth rate that is approximately 10 times lower than that of traditional trajectory feedbacks. The robustness of the optimized feedback system is studied for a number of additional imperfections, e.g., dipole corrector imperfections and faulty knowledge about the machine optics, with promising results.

Self-esteem threat combined with exposure to thin media images leads to body image compensatory self-enhancement.

PubMed

Jarry, Josée L; Kossert, Amy L

2007-03-01

This study examined the effect of a self-esteem threat combined with exposure to thin images on body image (BI) satisfaction and investment. Female participants (N=94) received a self-esteem threat consisting of false failure feedback or received false success feedback on an intellectual task allegedly highly predictive of academic and professional success. They then viewed media images featuring thin models or products. After viewing thin models, women who had received failure feedback declared themselves more satisfied about their appearance and less invested in it than did women who had received success feedback. These results suggest that exposure to the thin ideal may inspire women experiencing self-esteem threats to use appearance as an alternative source of worth, thus maintaining their global esteem through BI compensatory self-enhancement. Potential long-term implications of this strategy, such as a paradoxical increase in BI investment and the development of eating pathology, are discussed.

Underwater Chaotic Lidar using Blue Laser Diodes

NASA Astrophysics Data System (ADS)

Rumbaugh, Luke K.

The thesis proposes and explores an underwater lidar system architecture based on chaotic modulation of recently introduced, commercially available, low cost blue laser diodes. This approach is experimentally shown to allow accurate underwater impulse response measurements while eliminating the need for several major components typically found in high-performance underwater lidar systems. The proposed approach is to: 1. Generate wideband, noise-like intensity modulation signals using optical chaotic modulation of blue-green laser diodes, and then 2. Use this signal source to develop an underwater chaotic lidar system that uses no electrical signal generator, no electro-optic modulator, no optical frequency doubler, and no large-aperture photodetector. The outcome of this thesis is the demonstration of a new underwater lidar system architecture that could allow high resolution ranging, imaging, and water profiling measurements in turbid water, at a reduced size, weight, power and cost relative to state-of-the-art high-performance underwater lidar sensors. This work also makes contributions to the state of the art in optics, nonlinear dynamics, and underwater sensing by demonstrating for the first time: 1. Wideband noise-like intensity modulation of a blue laser diode using no electrical signal generator or electro-optic modulator. Optical chaotic modulation of a 462 nm blue InGaN laser diode by self-feedback is explored for the first time. The usefulness of the signal to chaotic lidar is evaluated in terms of bandwidth, modulation depth, and autocorrelation peak-to-sidelobe-ratio (PSLR) using both computer and laboratory experiments. In laboratory experiments, the optical feedback technique is shown to be effective in generating wideband, noise-like chaotic signals with strong modulation depth when the diode is operated in an external-cavity dominated state. The modulation signal strength is shown to be limited by the onset of lasing within the diode's internal cavity. The possibility of overcoming this limit by increasing optical feedback strength is discussed. 2. Power scaling in the blue-green spectrum using no optical frequency doubler. Synchronization of two 462 nm blue InGaN laser diodes by bi-directional optical injection is demonstrated for the first time in laboratory experiments. The improvement in chaotic intensity modulation signal strength is demonstrated to be 2.5x over the single-diode case. The signal strength is again shown to be limited by the onset of internal cavity lasing. The synchronized-laser arrangement is shown to be theoretically equivalent to a single-diode scenario in which the optical feedback is amplified by 2x, supporting the idea that increased optical feedback strength can be used to scale optical chaotic modulation of InGaN diodes to high powers. 3. Underwater impulse response measurements using a calibrated chaotic lidar system. An underwater chaotic lidar system using two synchronized diodes as transmitters is demonstrated in laboratory experiments for the first time. Reflective impulse response measurements using the lidar system are made in free space, and in a variety of clear and turbid water conditions, using a quasi-monostatic (i.e. co-located transmitter and receiver) arrangement. A calibration routine is implemented that increases accuracy and instantaneous dynamic range of the impulse response measurement, resulting in a baseline temporal resolution of 750 ps and a PSLR of over 10 dB. The calibrated system is shown to be able to simultaneously measure localized and distributed reflections, and to allow separation of the localized ( i.e. surface and target) reflections from the distributed ( i.e. backscatter) returns in several domains. Accurate range measurement with sub-inch typical error is demonstrated in laboratory water tank tests, which show accurate measurement through >6 feet of turbid water, as limited by the experimental water tank setup. Strong performance to the limit of the setup is shown at dwell times down to 1 mus. 4. Range measurement through turbid water using no large-aperture photodetector. The possibility of using a synchronized optical receiver to make range measurements through an attenuating channel (i.e. turbid water) is tested using two InGaN diodes for the first time. Using a variable optical attenuator to simulate channel attenuation, synchronization is maintained through 30 dB channel attenuation in the current experimental setup. Distance measurements are demonstrated by using the output of only one of the two diodes, suggesting that this method could be used to measure distance between two bi-static (i.e. physically separated), cooperative chaotic lidar systems in some water conditions. This thesis concludes that the proposed approach is a feasible path to a novel high resolution underwater lidar sensor capable of operating in turbid water, which would have significant size, weight, power, and cost reductions because it would not use an electrical signal generator, an electro-optic modulator, or an optical frequency doubler. The work also suggests the possibility of range measurement in a limited range of water conditions using no large-aperture photodetector, most feasibly in a bi-static cooperative arrangement.

Optical voltage reference

DOEpatents

Rankin, Richard; Kotter, Dale

1994-01-01

An optical voltage reference for providing an alternative to a battery source. The optical reference apparatus provides a temperature stable, high precision, isolated voltage reference through the use of optical isolation techniques to eliminate current and impedance coupling errors. Pulse rate frequency modulation is employed to eliminate errors in the optical transmission link while phase-lock feedback is employed to stabilize the frequency to voltage transfer function.

LED lamp color control system and method

DOEpatents

Gaines, James; Clauberg, Bernd; Van Erp, Josephus A.M.

2013-02-05

An LED lamp color control system and method including an LED lamp having an LED controller 58; and a plurality of LED channels 60 operably connected to the LED controller 58, each of the plurality of LED channels 60 having a channel switch 62 in series with at least one shunted LED circuit 83, the shunted LED circuit 83 having a shunt switch 68 in parallel with an LED source 80. The LED controller 58 determines whether the LED source 80 is in a feedback controllable range, stores measured optical flux for the LED source 80 when the LED source 80 is in the feedback controllable range, and bypasses storing the measured optical flux when the LED source 80 is not in the feedback controllable range.

Micromachined diffraction based optical microphones and intensity probes with electrostatic force feedback

NASA Astrophysics Data System (ADS)

Bicen, Baris

Measuring acoustic pressure gradients is critical in many applications such as directional microphones for hearing aids and sound intensity probes. This measurement is especially challenging with decreasing microphone size, which reduces the sensitivity due to small spacing between the pressure ports. Novel, micromachined biomimetic microphone diaphragms are shown to provide high sensitivity to pressure gradients on one side of the diaphragm with low thermal mechanical noise. These structures have a dominant mode shape with see-saw like motion in the audio band, responding to pressure gradients as well as spurious higher order modes sensitive to pressure. In this dissertation, integration of a diffraction based optical detection method with these novel diaphragm structures to implement a low noise optical pressure gradient microphone is described and experimental characterization results are presented, showing 36 dBA noise level with 1mm port spacing, nearly an order of magnitude better than the current gradient microphones. The optical detection scheme also provides electrostatic actuation capability from both sides of the diaphragm separately which can be used for active force feedback. A 4-port electromechanical equivalent circuit model of this microphone with optical readout is developed to predict the overall response of the device to different acoustic and electrostatic excitations. The model includes the damping due to complex motion of air around the microphone diaphragm, and it calculates the detected optical signal on each side of the diaphragm as a combination of two separate dominant vibration modes. This equivalent circuit model is verified by experiments and used to predict the microphone response with different force feedback schemes. Single sided force feedback is used for active damping to improve the linearity and the frequency response of the microphone. Furthermore, it is shown that using two sided force feedback one can significantly suppress or enhance the desired vibration modes of the diaphragm. This approach provides an electronic means to tailor the directional response of the microphones, with significant implications in device performance for various applications. As an example, the use of this device as a particle velocity sensor for sound intensity and sound power measurements is investigated. Without force feedback, the gradient microphone provides accurate particle velocity measurement for frequencies below 2 kHz, after which the pressure response of the second order mode becomes significant. With two-sided force feedback, the calculations show that this upper frequency limit may be increased to 10 kHz. This improves the pressure residual intensity index by more than 15 dB in the 50 Hz--10 kHz range, matching the Class I requirements of IEC 1043 standards for intensity probes without any need for multiple spacers.

Optogenetic feedback control of neural activity

PubMed Central

Newman, Jonathan P; Fong, Ming-fai; Millard, Daniel C; Whitmire, Clarissa J; Stanley, Garrett B; Potter, Steve M

2015-01-01

Optogenetic techniques enable precise excitation and inhibition of firing in specified neuronal populations and artifact-free recording of firing activity. Several studies have suggested that optical stimulation provides the precision and dynamic range requisite for closed-loop neuronal control, but no approach yet permits feedback control of neuronal firing. Here we present the ‘optoclamp’, a feedback control technology that provides continuous, real-time adjustments of bidirectional optical stimulation in order to lock spiking activity at specified targets over timescales ranging from seconds to days. We demonstrate how this system can be used to decouple neuronal firing levels from ongoing changes in network excitability due to multi-hour periods of glutamatergic or GABAergic neurotransmission blockade in vitro as well as impinging vibrissal sensory drive in vivo. This technology enables continuous, precise optical control of firing in neuronal populations in order to disentangle causally related variables of circuit activation in a physiologically and ethologically relevant manner. DOI: http://dx.doi.org/10.7554/eLife.07192.001 PMID:26140329

A 12 GHz wavelength spacing multi-wavelength laser source for wireless communication systems

NASA Astrophysics Data System (ADS)

Peng, P. C.; Shiu, R. K.; Bitew, M. A.; Chang, T. L.; Lai, C. H.; Junior, J. I.

2017-08-01

This paper presents a multi-wavelength laser source with 12 GHz wavelength spacing based on a single distributed feedback laser. A light wave generated from the distributed feedback laser is fed into a frequency shifter loop consisting of 50:50 coupler, dual-parallel Mach-Zehnder modulator, optical amplifier, optical filter, and polarization controller. The frequency of the input wavelength is shifted and then re-injected into the frequency shifter loop. By re-injecting the shifted wavelengths multiple times, we have generated 84 optical carriers with 12 GHz wavelength spacing and stable output power. For each channel, two wavelengths are modulated by a wireless data using the phase modulator and transmitted through a 25 km single mode fiber. In contrast to previously developed schemes, the proposed laser source does not incur DC bias drift problem. Moreover, it is a good candidate for radio-over-fiber systems to support multiple users using a single distributed feedback laser.

Demons registration for in vivo and deformable laser scanning confocal endomicroscopy.

PubMed

Chiew, Wei-Ming; Lin, Feng; Seah, Hock Soon

2017-09-01

A critical effect found in noninvasive in vivo endomicroscopic imaging modalities is image distortions due to sporadic movement exhibited by living organisms. In three-dimensional confocal imaging, this effect results in a dataset that is tilted across deeper slices. Apart from that, the sequential flow of the imaging-processing pipeline restricts real-time adjustments due to the unavailability of information obtainable only from subsequent stages. To solve these problems, we propose an approach to render Demons-registered datasets as they are being captured, focusing on the coupling between registration and visualization. To improve the acquisition process, we also propose a real-time visual analytics tool, which complements the imaging pipeline and the Demons registration pipeline with useful visual indicators to provide real-time feedback for immediate adjustments. We highlight the problem of deformation within the visualization pipeline for object-ordered and image-ordered rendering. Visualizations of critical information including registration forces and partial renderings of the captured data are also presented in the analytics system. We demonstrate the advantages of the algorithmic design through experimental results with both synthetically deformed datasets and actual in vivo, time-lapse tissue datasets expressing natural deformations. Remarkably, this algorithm design is for embedded implementation in intelligent biomedical imaging instrumentation with customizable circuitry. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

Effects of Training and Feedback on Accuracy of Predicting Rectosigmoid Neoplastic Lesions and Selection of Surveillance Intervals by Endoscopists Performing Optical Diagnosis of Diminutive Polyps.

PubMed

Vleugels, Jasper L A; Dijkgraaf, Marcel G W; Hazewinkel, Yark; Wanders, Linda K; Fockens, Paul; Dekker, Evelien

2018-05-01

Real-time differentiation of diminutive polyps (1-5 mm) during endoscopy could replace histopathology analysis. According to guidelines, implementation of optical diagnosis into routine practice would require it to identify rectosigmoid neoplastic lesions with a negative predictive value (NPV) of more than 90%, using histologic findings as a reference, and agreement with histology-based surveillance intervals for more than 90% of cases. We performed a prospective study with 39 endoscopists accredited to perform colonoscopies on participants with positive results from fecal immunochemical tests in the Bowel Cancer Screening Program at 13 centers in the Netherlands. Endoscopists were trained in optical diagnosis using a validated module (Workgroup serrAted polypS and Polyposis). After meeting predefined performance thresholds in the training program, the endoscopists started a 1-year program (continuation phase) in which they performed narrow band imaging analyses during colonoscopies of participants in the screening program and predicted histological findings with confidence levels. The endoscopists were randomly assigned to groups that received feedback or no feedback on the accuracy of their predictions. Primary outcome measures were endoscopists' abilities to identify rectosigmoid neoplastic lesions (using histology as a reference) with NPVs of 90% or more, and selecting surveillance intervals that agreed with those determined by histology for at least 90% of cases. Of 39 endoscopists initially trained, 27 (69%) completed the training program. During the continuation phase, these 27 endoscopists performed 3144 colonoscopies in which 4504 diminutive polyps were removed. The endoscopists identified neoplastic lesions with a pooled NPV of 90.8% (95% confidence interval 88.6-92.6); their proposed surveillance intervals agreed with those determined by histologic analysis for 95.4% of cases (95% confidence interval 94.0-96.6). Findings did not differ between the group that did vs did not receive feedback. Sixteen endoscopists (59%) identified rectosigmoid neoplastic lesions with NPVs greater than 90% and selected surveillance intervals in agreement with those determined from histology for more than 90% of patients. In a prospective study following a validated training module, we found that a selected group of endoscopists identified rectosigmoid neoplastic lesions with pooled NPVs greater than 90% and accurately selected surveillance intervals for more than 90% of patients over the course of 1 year. Providing regular interim feedback on the accuracy of neoplastic lesion prediction and surveillance interval selection did not lead to differences in those endpoints. Monitoring is suggested, as individual performance varied. ClinicalTrials.gov no: NCT02516748; Netherland Trial Register: NTR4635. Copyright © 2018 AGA Institute. Published by Elsevier Inc. All rights reserved.

Sensing interactions in the microworld with optical tweezers

NASA Astrophysics Data System (ADS)

Pacoret, Cécile; Bowman, Richard; Gibson, Graham; Sinan, Haliyo D.; Bergander, Arvid; Carberry, David; Régnier, Stéphane; Padgett, Miles

2009-08-01

Optical Tweezers have become a widespread tool in Cell Biology, microengineering and other fields requiring delicate micromanipulation. But for those sensitive tasks, it remains difficult to handle objects without damaging them. As the precision in position and force measurement increase, the richness of information cannot be fully exploited with simple interfaces such as a mouse or a common joystick. For this reason, we propose a haptic force-feedback optical tweezer command and a force-feedback system controlled by one hand. The system combines accurate force measurement using a fast camera and the coupling of these measured forces with a human operator. The overall transparency allows even the feeling of the Brownian motion.

Dynamic autofocus for continuous-scanning time-delay-and-integration image acquisition in automated microscopy.

PubMed

Bravo-Zanoguera, Miguel E; Laris, Casey A; Nguyen, Lam K; Oliva, Mike; Price, Jeffrey H

2007-01-01

Efficient image cytometry of a conventional microscope slide means rapid acquisition and analysis of 20 gigapixels of image data (at 0.3-microm sampling). The voluminous data motivate increased acquisition speed to enable many biomedical applications. Continuous-motion time-delay-and-integrate (TDI) scanning has the potential to speed image acquisition while retaining sensitivity, but the challenge of implementing high-resolution autofocus operating simultaneously with acquisition has limited its adoption. We develop a dynamic autofocus system for this need using: 1. a "volume camera," consisting of nine fiber optic imaging conduits to charge-coupled device (CCD) sensors, that acquires images in parallel from different focal planes, 2. an array of mixed analog-digital processing circuits that measure the high spatial frequencies of the multiple image streams to create focus indices, and 3. a software system that reads and analyzes the focus data streams and calculates best focus for closed feedback loop control. Our system updates autofocus at 56 Hz (or once every 21 microm of stage travel) to collect sharply focused images sampled at 0.3x0.3 microm(2)/pixel at a stage speed of 2.3 mms. The system, tested by focusing in phase contrast and imaging long fluorescence strips, achieves high-performance closed-loop image-content-based autofocus in continuous scanning for the first time.

Optical frequency stabilization in infrared region using improved dual feed-back loop

NASA Astrophysics Data System (ADS)

Ružička, B.; Číp, O.; Lazar, J.

2007-03-01

Modern technologies such as DWDM (Dense Wavelength Division Multiplex) need precise stability of laser frequencies. According to this fact, requirements of new etalons of optical frequencies in the telecommunication band is rapidly growing. Lasers working in near infrared telecommunication band (1500-1600 nm) can be stabilized to 12C IIH II or 13C IIH II (acetylene) gas absorption lines. The acetylene gas absorption has been widely studied and accepted by international bodies of standardization as a primary wavelength reference in the near infrared band around 1550 nm. Our aim was to design and develop a compact fibre optics laser system generating coherent light in near-IR band with high frequency stability (at least 1.10 -8). This system should become a base for realization of a primary frequency standard for optical communications in the Czech Republic. Such an etalon will be needed for calibration of wavelengthmeters and spectral analysers for DWDM communication systems. We are co-operating with CMI (Czech Metrology Institute) on this project. We present stabilized laser system based on a single frequency DFB (Distributed Feedback) laser diode with a narrow spectral profile. The laser is pre-stabilized by means of the FM-spectroscopy on a passive resonator. Thanks to a fast feed-back loop we are able to improve spectral characteristics of the laser. The laser frequency is locked by a relatively slow second feed-back loop on an absorption line of acetylene vapour which is sealed in a cell under the optimised pressure.

Spectral radiance source based on supercontinuum laser and wavelength tunable bandpass filter: the spectrally tunable absolute irradiance and radiance source.

PubMed

Levick, Andrew P; Greenwell, Claire L; Ireland, Jane; Woolliams, Emma R; Goodman, Teresa M; Bialek, Agnieszka; Fox, Nigel P

2014-06-01

A new spectrally tunable source for calibration of radiometric detectors in radiance, irradiance, or power mode has been developed and characterized. It is termed the spectrally tunable absolute irradiance and radiance source (STAIRS). It consists of a supercontinuum laser, wavelength tunable bandpass filter, power stabilization feedback control scheme, and output coupling optics. It has the advantages of relative portability and a collimated beam (low étendue), and is an alternative to conventional sources such as tungsten lamps, blackbodies, or tunable lasers. The supercontinuum laser is a commercial Fianium SC400-6-02, which has a wavelength range between 400 and 2500 nm and a total power of 6 W. The wavelength tunable bandpass filter, a PhotonEtc laser line tunable filter (LLTF), is tunable between 400 and 1000 nm and has a bandwidth of 1 or 2 nm depending on the wavelength selected. The collimated laser beam from the LLTF filter is converted to an appropriate spatial and angular distribution for the application considered (i.e., for radiance, irradiance, or power mode calibration of a radiometric sensor) with the output coupling optics, for example, an integrating sphere, and the spectral radiance/irradiance/power of the source is measured using a calibration optical sensor. A power stabilization feedback control scheme has been incorporated that stabilizes the source to better than 0.01% for averaging times longer than 100 s. The out-of-band transmission of the LLTF filter is estimated to be < -65 dB (0.00003%), and is sufficiently low for many end-user applications, for example the spectral radiance calibration of earth observation imaging radiometers and the stray light characterization of array spectrometers (the end-user optical sensor). We have made initial measurements of two end-user instruments with the STAIRS source, an array spectrometer and ocean color radiometer.

Optical voltage reference

DOEpatents

Rankin, R.; Kotter, D.

1994-04-26

An optical voltage reference for providing an alternative to a battery source is described. The optical reference apparatus provides a temperature stable, high precision, isolated voltage reference through the use of optical isolation techniques to eliminate current and impedance coupling errors. Pulse rate frequency modulation is employed to eliminate errors in the optical transmission link while phase-lock feedback is employed to stabilize the frequency to voltage transfer function. 2 figures.

Ionized Gas Motions and the Structure of Feedback near a Forming Globular Cluster in NGC 5253

NASA Astrophysics Data System (ADS)

Cohen, Daniel P.; Turner, Jean L.; Consiglio, S. Michelle; Martin, Emily C.; Beck, Sara C.

2018-06-01

We observed Brackett α 4.05 μm emission toward the supernebula in NGC 5253 with NIRSPEC on Keck II in adaptive optics mode, NIRSPAO, to probe feedback from its exciting embedded super star cluster (SSC). NIRSPEC's Slit-viewing Camera was simultaneously used to image the K-band continuum at ∼0.″1 resolution. We register the IR continuum with HST imaging, and find that the visible clusters are offset from the K-band peak, which coincides with the Brα peak of the supernebula and its associated molecular cloud. The spectra of the supernebula exhibit Brα emission with a strong, narrow core. The linewidths are 65–76 km s‑1, FWHM, comparable to those around individual ultra-compact H II regions within our Galaxy. A weak, broad (FWHM ≃ 150–175 km s‑1) component is detected on the base of the line, which could trace a population of sources with high-velocity winds. The core velocity of Brα emission shifts by +13 km s‑1 from NE to SW across the supernebula, possibly indicating a bipolar outflow from an embedded object or a link to a foreground redshifted gas filament. The results can be explained if the supernebula comprises thousands of ionized wind regions around individual massive stars, stalled in their expansion due to critical radiative cooling and unable to merge to drive a coherent cluster wind. Based on the absence of an outflow with large mass loss, we conclude that feedback is currently ineffective at dispersing gas, and the SSC retains enriched material out of which it may continue to form stars.

The ages and baryonic masses of clumps in turbulent, clumpy disk galaxies

NASA Astrophysics Data System (ADS)

Fisher, David

2017-08-01

We propose to measure the stellar populations and masses of massive star forming clumps at the resolution of the Jeans' length in a sample of massive, turbulent disk galaxies. Massive star-forming clumps are a critical component of the morphogical transformation of galaxies and the build-up of bulges. If, however, clumps dissipate quickly bulges may not form through clump phase, then clumps would build thick disks. Different feedback prescriptions have drastically different effects on clumps. Some feedback models (e.g. Hopkins et al 2012, FIRE simulations) completely destroy clumps whereas other feedback models allow clumps to persist (e.g. Bournaud et al. 2014). Therefore, to build accurate models of galaxy evolution we must know how long the lives of clumps are. The problem is that both due to resolution and available wavelength coverage it is impossible to precisely measure the ages and stellar masses of individual clumps in high-z galaxies. We have discovered a sample of extremely rare galaxies at z 0.1 that are extremely gas rich, turbulent and have a clumpy distribution of ionized gas. In all ways they are identical to those of the high-redshift Universe. We propose to employ UV-optical-near IR imaging with WFC3 to measure the stellar masses and mean ages of a set of 6 clumpy galaxies, containing 80 giant star forming clumps. This data complements our ALMA CO(1-0) maps of the same targets, and we will thus make the first maps of the full baryonic mass in turbulent disk galaxies. This work builds on our previous HST Halpha imaging program, and validates massive investments of HST time on high-z surveys of galaxies.

An Estimate of Low-Cloud Feedbacks from Variations of Cloud Radiative and Physical Properties with Sea Surface Temperature on Interannual Time Scales

NASA Technical Reports Server (NTRS)

Eitzen, Zachary A.; Xu, Kuan-Man; Wong, Takmeng

2011-01-01

Simulations of climate change have yet to reach a consensus on the sign and magnitude of the changes in physical properties of marine boundary layer clouds. In this study, the authors analyze how cloud and radiative properties vary with SST anomaly in low-cloud regions, based on five years (March 2000 - February 2005) of Clouds and the Earth s Radiant Energy System (CERES) -- Terra monthly gridded data and matched European Centre for Medium-Range Weather Forecasts (ECMWF) meteorological reanalaysis data. In particular, this study focuses on the changes in cloud radiative effect, cloud fraction, and cloud optical depth with SST anomaly. The major findings are as follows. First, the low-cloud amount (-1.9% to -3.4% /K) and the logarithm of low-cloud optical depth (-0.085 to -0.100/K) tend to decrease while the net cloud radiative effect (3.86 W/m(exp 2)/ K) becomes less negative as SST anomalies increase. These results are broadly consistent with previous observational studies. Second, after the changes in cloud and radiative properties with SST anomaly are separated into dynamic, thermodynamic, and residual components, changes in the dynamic component (taken as the vertical velocity at 700 hPa) have relatively little effect on cloud and radiative properties. However, the estimated inversion strength decreases with increasing SST, accounting for a large portion of the measured decreases in cloud fraction and cloud optical depth. The residual positive change in net cloud radiative effect (1.48 W/m(exp 2)/ K) and small changes in low-cloud amount (-0.81% to 0.22% /K) and decrease in the logarithm of optical depth (-0.035 to -0.046/ K) with SST are interpreted as a positive cloud feedback, with cloud optical depth feedback being the dominant contributor. Last, the magnitudes of the residual changes differ greatly among the six low-cloud regions examined in this study, with the largest positive feedbacks (approximately 4 W/m(exp 2)/ K) in the southeast and northeast Atlantic regions and a slightly negative feedback (-0.2 W/m(exp 2)/ K) in the south-central Pacific region. Because the retrievals of cloud optical depth and/or cloud fraction are difficult in the presence of aerosols, the transport of heavy African continental aerosols may contribute to the large magnitudes of estimated cloud feedback in the two Atlantic regions.

An exposure indicator for digital radiography: AAPM Task Group 116 (executive summary).

PubMed

Shepard, S Jeff; Wang, Jihong; Flynn, Michael; Gingold, Eric; Goldman, Lee; Krugh, Kerry; Leong, David L; Mah, Eugene; Ogden, Kent; Peck, Donald; Samei, Ehsan; Wang, Jihong; Willis, Charles E

2009-07-01

Digital radiographic imaging systems, such as those using photostimulable storage phosphor, amorphous selenium, amorphous silicon, CCD, and MOSFET technology, can produce adequate image quality over a much broader range of exposure levels than that of screen/film imaging systems. In screen/film imaging, the final image brightness and contrast are indicative of over- and underexposure. In digital imaging, brightness and contrast are often determined entirely by digital postprocessing of the acquired image data. Overexposure and underexposures are not readily recognizable. As a result, patient dose has a tendency to gradually increase over time after a department converts from screen/film-based imaging to digital radiographic imaging. The purpose of this report is to recommend a standard indicator which reflects the radiation exposure that is incident on a detector after every exposure event and that reflects the noise levels present in the image data. The intent is to facilitate the production of consistent, high quality digital radiographic images at acceptable patient doses. This should be based not on image optical density or brightness but on feedback regarding the detector exposure provided and actively monitored by the imaging system. A standard beam calibration condition is recommended that is based on RQA5 but uses filtration materials that are commonly available and simple to use. Recommendations on clinical implementation of the indices to control image quality and patient dose are derived from historical tolerance limits and presented as guidelines.

An exposure indicator for digital radiography: AAPM Task Group 116 (Executive Summary)

PubMed Central

Shepard, S. Jeff; Wang, Jihong; Flynn, Michael; Gingold, Eric; Goldman, Lee; Krugh, Kerry; Leong, David L.; Mah, Eugene; Ogden, Kent; Peck, Donald; Samei, Ehsan; Wang, Jihong; Willis, Charles E.

2009-01-01

Digital radiographic imaging systems, such as those using photostimulable storage phosphor, amorphous selenium, amorphous silicon, CCD, and MOSFET technology, can produce adequate image quality over a much broader range of exposure levels than that of screen/film imaging systems. In screen/film imaging, the final image brightness and contrast are indicative of over- and underexposure. In digital imaging, brightness and contrast are often determined entirely by digital postprocessing of the acquired image data. Overexposure and underexposures are not readily recognizable. As a result, patient dose has a tendency to gradually increase over time after a department converts from screen/film-based imaging to digital radiographic imaging. The purpose of this report is to recommend a standard indicator which reflects the radiation exposure that is incident on a detector after every exposure event and that reflects the noise levels present in the image data. The intent is to facilitate the production of consistent, high quality digital radiographic images at acceptable patient doses. This should be based not on image optical density or brightness but on feedback regarding the detector exposure provided and actively monitored by the imaging system. A standard beam calibration condition is recommended that is based on RQA5 but uses filtration materials that are commonly available and simple to use. Recommendations on clinical implementation of the indices to control image quality and patient dose are derived from historical tolerance limits and presented as guidelines. PMID:19673189

Leaders’ Expressed Humility and Followers’ Feedback Seeking: The Mediating Effects of Perceived Image Cost and Moderating Effects of Power Distance Orientation

PubMed Central

Qian, Jing; Li, Xiaoyan; Song, Baihe; Wang, Bin; Wang, Menghan; Chang, Shumeng; Xiong, Yujiao

2018-01-01

We developed and tested a model to identify the role of leaders’ expressed humility on employees’ feedback-seeking processes. The data used in our study was from a sample of 248 employees and 57 of their immediate supervisors. The results revealed that: (1) leader’s expressed humility positively related to employees’ feedback seeking mediated by employees’ perceived image cost; and (2) power distance orientation moderated the relationship between leader’s expressed humility and employees’ perceived image costs, such that the relationship was stronger when the power distance orientation was lower rather than higher. The results offer new insight into potential managerial practices that aim at stimulating feedback seeking. We conclude with a discussion for future research. PMID:29720956

The Role of Star Formation in Radio-Loud Galaxy Groups

NASA Astrophysics Data System (ADS)

Herbst, Hanna; Wilcots, E.; Hess, K.

2010-01-01

X-ray observations have shown that additional non-gravitational processes are required to explain the heating of the intergalactic medium in galaxy groups. The two most likely processes are galactic outflows from starbursts and feedback from AGN. Here, we look at star formation as a possible additional heating mechanism in X-ray luminous groups such as NGC 741, NGC 1052, NGC 524, and NGC 1587. We report on the results of optical imaging of these groups carried out using the WIYN 3.5m telescope with a specific emphasis on measuring the star formation rates of the resident galaxies in each group and estimating the impact of that star formation on the thermodynamics of the intragroup medium.

Quantifying the radiative and microphysical impacts of fire aerosols on cloud dynamics in the tropics using temporally offset satellite observations

NASA Astrophysics Data System (ADS)

Tosca, M. G.; Diner, D. J.; Garay, M. J.; Kalashnikova, O.

2013-12-01

Anthropogenic fires in Southeast Asia and Central America emit smoke that affects cloud dynamics, meteorology, and climate. We measured the cloud response to direct and indirect forcing from biomass burning aerosols using aerosol retrievals from the Multi-angle Imaging SpectroRadiometer (MISR) and non-synchronous cloud retrievals from the MODerate resolution Imaging Spectroradiometer (MODIS) from collocated morning and afternoon overpasses. Level 2 data from thirty-one individual scenes acquired between 2006 and 2010 were used to quantify changes in cloud fraction, cloud droplet size, cloud optical depth and cloud top temperature from morning (10:30am local time) to afternoon (1:30pm local time) in the presence of varying aerosol burdens. We accounted for large-scale meteorological differences between scenes by normalizing observed changes to the mean difference per individual scene. Elevated AODs reduced cloud fraction and cloud droplet size and increased cloud optical depths in both Southeast Asia and Central America. In mostly cloudy regions, aerosols significantly reduced cloud fraction and cloud droplet sizes, but in clear skies, cloud fraction, cloud optical thickness and cloud droplet sizes increased. In clouds with vertical development, aerosols reduced cloud fraction via semi-direct effects but spurred cloud growth via indirect effects. These results imply a positive feedback loop between anthropogenic burning and cloudiness in both Central America and Southeast Asia, and are consistent with previous studies linking smoke aerosols to both cloud reduction and convective invigoration.

Intraocular camera for retinal prostheses: Refractive and diffractive lens systems

NASA Astrophysics Data System (ADS)

Hauer, Michelle Christine

The focus of this thesis is on the design and analysis of refractive, diffractive, and hybrid refractive/diffractive lens systems for a miniaturized camera that can be surgically implanted in the crystalline lens sac and is designed to work in conjunction with current and future generation retinal prostheses. The development of such an intraocular camera (IOC) would eliminate the need for an external head-mounted or eyeglass-mounted camera. Placing the camera inside the eye would allow subjects to use their natural eye movements for foveation (attention) instead of more cumbersome head tracking, would notably aid in personal navigation and mobility, and would also be significantly more psychologically appealing from the standpoint of personal appearances. The capability for accommodation with no moving parts or feedback control is incorporated by employing camera designs that exhibit nearly infinite depth of field. Such an ultracompact optical imaging system requires a unique combination of refractive and diffractive optical elements and relaxed system constraints derived from human psychophysics. This configuration necessitates an extremely compact, short focal-length lens system with an f-number close to unity. Initially, these constraints appear highly aggressive from an optical design perspective. However, after careful analysis of the unique imaging requirements of a camera intended to work in conjunction with the relatively low pixellation levels of a retinal microstimulator array, it becomes clear that such a design is not only feasible, but could possibly be implemented with a single lens system.

Holistic assessment of covalently-labelled core-shell polymeric nanoparticles with fluorescent contrast agents towards theranostic applications

PubMed Central

Gustafson, Tiffany P.; Lim, Young H.; Flores, Jeniree A.; Heo, Gyu Seong; Zhang, Fuwu; Zhang, Shiyi; Samarajeewa, Sandani; Raymond, Jeffery E.; Wooley, Karen L.

2014-01-01

The successful development of degradable polymeric nanostructures as optical probes for use in nanotheranostic applications requires the intelligent design of materials such that their surface response, degradation, drug delivery and imaging properties are all optimized. In the case of imaging, optimization must result in materials that allow differentiation between unbound optical contrast agents and labeled polymeric materials as they undergo degradation. In this study, we have shown that use of traditional electrophoretic gel-plate assays for determination of the purity of dye-conjugated degradable nanoparticles is limited, due to polymer degradation characteristics. To overcome these limitations, we have outlined a holistic approach to evaluating dye-and peptide-polymer nanoparticle conjugation by utilizing steady-state fluorescence, anisotropy, and emission and anisotropy life-time decay profiles, through which nanoparticle-dye binding can be assessed independent of perturbations, such as those presented during the execution of electrolyte gel-based assays. This approach has been demonstrated to provide an overall understanding of the spectral signature-structure-function relationship, ascertaining key information on interactions between the fluorophore, polymer and solvent components that have a direct and measurable impact on the emissive properties of the optical probe. The use of these powerful techniques provides feedback that can be utilized to improve nanotheranostics by evaluating dye emissivity in degradable nanotheranostic systems, which has become increasingly important as modern platforms transition to architectures intentionally reliant on degradation and built-in environmental responses. PMID:24392760

Analysis of the color rendition of flexible endoscopes

NASA Astrophysics Data System (ADS)

Murphy, Edward M.; Hegarty, Francis J.; McMahon, Barry P.; Boyle, Gerard

2003-03-01

Endoscopes are imaging devices routinely used for the diagnosis of disease within the human digestive tract. Light is transmitted into the body cavity via incoherent fibreoptic bundles and is controlled by a light feedback system. Fibreoptic endoscopes use coherent fibreoptic bundles to provide the clinician with an image. It is also possible to couple fibreoptic endoscopes to a clip-on video camera. Video endoscopes consist of a small CCD camera, which is inserted into gastrointestinal tract, and associated image processor to convert the signal to analogue RGB video signals. Images from both types of endoscope are displayed on standard video monitors. Diagnosis is dependent upon being able to determine changes in the structure and colour of tissues and biological fluids, and therefore is dependent upon the ability of the endoscope to reproduce the colour of these tissues and fluids with fidelity. This study investigates the colour reproduction of flexible optical and video endoscopes. Fibreoptic and video endoscopes alter image colour characteristics in different ways. The colour rendition of fibreoptic endoscopes was assessed by coupling them to a video camera and applying video colorimetric techniques. These techniques were then used on video endoscopes to assess how the colour rendition of video endoscopes compared with that of optical endoscopes. In both cases results were obtained at fixed illumination settings. Video endoscopes were then assessed with varying levels of illumination. Initial results show that at constant luminance endoscopy systems introduce non-linear shifts in colour. Techniques for examining how this colour shift varies with illumination intensity were developed and both methodology and results will be presented. We conclude that more rigorous quality assurance is required to reduce colour error and are developing calibration procedures applicable to medical endoscopes.

Reliability and relative weighting of visual and nonvisual information for perceiving direction of self-motion during walking

PubMed Central

Saunders, Jeffrey A.

2014-01-01

Direction of self-motion during walking is indicated by multiple cues, including optic flow, nonvisual sensory cues, and motor prediction. I measured the reliability of perceived heading from visual and nonvisual cues during walking, and whether cues are weighted in an optimal manner. I used a heading alignment task to measure perceived heading during walking. Observers walked toward a target in a virtual environment with and without global optic flow. The target was simulated to be infinitely far away, so that it did not provide direct feedback about direction of self-motion. Variability in heading direction was low even without optic flow, with average RMS error of 2.4°. Global optic flow reduced variability to 1.9°–2.1°, depending on the structure of the environment. The small amount of variance reduction was consistent with optimal use of visual information. The relative contribution of visual and nonvisual information was also measured using cue conflict conditions. Optic flow specified a conflicting heading direction (±5°), and bias in walking direction was used to infer relative weighting. Visual feedback influenced heading direction by 16%–34% depending on scene structure, with more effect with dense motion parallax. The weighting of visual feedback was close to the predictions of an optimal integration model given the observed variability measures. PMID:24648194

Web-based, GPU-accelerated, Monte Carlo simulation and visualization of indirect radiation imaging detector performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dong, Han; Sharma, Diksha; Badano, Aldo, E-mail: aldo.badano@fda.hhs.gov

2014-12-15

Purpose: Monte Carlo simulations play a vital role in the understanding of the fundamental limitations, design, and optimization of existing and emerging medical imaging systems. Efforts in this area have resulted in the development of a wide variety of open-source software packages. One such package, hybridMANTIS, uses a novel hybrid concept to model indirect scintillator detectors by balancing the computational load using dual CPU and graphics processing unit (GPU) processors, obtaining computational efficiency with reasonable accuracy. In this work, the authors describe two open-source visualization interfaces, webMANTIS and visualMANTIS to facilitate the setup of computational experiments via hybridMANTIS. Methods: Themore » visualization tools visualMANTIS and webMANTIS enable the user to control simulation properties through a user interface. In the case of webMANTIS, control via a web browser allows access through mobile devices such as smartphones or tablets. webMANTIS acts as a server back-end and communicates with an NVIDIA GPU computing cluster that can support multiuser environments where users can execute different experiments in parallel. Results: The output consists of point response and pulse-height spectrum, and optical transport statistics generated by hybridMANTIS. The users can download the output images and statistics through a zip file for future reference. In addition, webMANTIS provides a visualization window that displays a few selected optical photon path as they get transported through the detector columns and allows the user to trace the history of the optical photons. Conclusions: The visualization tools visualMANTIS and webMANTIS provide features such as on the fly generation of pulse-height spectra and response functions for microcolumnar x-ray imagers while allowing users to save simulation parameters and results from prior experiments. The graphical interfaces simplify the simulation setup and allow the user to go directly from specifying input parameters to receiving visual feedback for the model predictions.« less

Functional imaging of cortical feedback projections to the olfactory bulb

PubMed Central

Rothermel, Markus; Wachowiak, Matt

2014-01-01

Processing of sensory information is substantially shaped by centrifugal, or feedback, projections from higher cortical areas, yet the functional properties of these projections are poorly characterized. Here, we used genetically-encoded calcium sensors (GCaMPs) to functionally image activation of centrifugal projections targeting the olfactory bulb (OB). The OB receives massive centrifugal input from cortical areas but there has been as yet no characterization of their activity in vivo. We focused on projections to the OB from the anterior olfactory nucleus (AON), a major source of cortical feedback to the OB. We expressed GCaMP selectively in AON projection neurons using a mouse line expressing Cre recombinase (Cre) in these neurons and Cre-dependent viral vectors injected into AON, allowing us to image GCaMP fluorescence signals from their axon terminals in the OB. Electrical stimulation of AON evoked large fluorescence signals that could be imaged from the dorsal OB surface in vivo. Surprisingly, odorants also evoked large signals that were transient and coupled to odorant inhalation both in the anesthetized and awake mouse, suggesting that feedback from AON to the OB is rapid and robust across different brain states. The strength of AON feedback signals increased during wakefulness, suggesting a state-dependent modulation of cortical feedback to the OB. Two-photon GCaMP imaging revealed that different odorants activated different subsets of centrifugal AON axons and could elicit both excitation and suppression in different axons, indicating a surprising richness in the representation of odor information by cortical feedback to the OB. Finally, we found that activating neuromodulatory centers such as basal forebrain drove AON inputs to the OB independent of odorant stimulation. Our results point to the AON as a multifunctional cortical area that provides ongoing feedback to the OB and also serves as a descending relay for other neuromodulatory systems. PMID:25071454

Optical atomic magnetometer

DOEpatents

Budker, Dmitry; Higbie, James; Corsini, Eric P.

2013-11-19

An optical atomic magnetometers is provided operating on the principles of nonlinear magneto-optical rotation. An atomic vapor is optically pumped using linearly polarized modulated light. The vapor is then probed using a non-modulated linearly polarized light beam. The resulting modulation in polarization angle of the probe light is detected and used in a feedback loop to induce self-oscillation at the resonant frequency.

Quantum feedback cooling of a mechanical oscillator using variational measurements: tweaking Heisenberg’s microscope

NASA Astrophysics Data System (ADS)

Habibi, Hojat; Zeuthen, Emil; Ghanaatshoar, Majid; Hammerer, Klemens

2016-08-01

We revisit the problem of preparing a mechanical oscillator in the vicinity of its quantum-mechanical ground state by means of feedback cooling based on continuous optical detection of the oscillator position. In the parameter regime relevant to ground-state cooling, the optical back-action and imprecision noise set the bottleneck of achievable cooling and must be carefully balanced. This can be achieved by adapting the phase of the local oscillator in the homodyne detection realizing a so-called variational measurement. The trade-off between accurate position measurement and minimal disturbance can be understood in terms of Heisenberg’s microscope and becomes particularly relevant when the measurement and feedback processes happen to be fast within the quantum coherence time of the system to be cooled. This corresponds to the regime of large quantum cooperativity {C}{{q}}≳ 1, which was achieved in recent experiments on feedback cooling. Our method provides a simple path to further pushing the limits of current state-of-the-art experiments in quantum optomechanics.

Designing a stable feedback control system for blind image deconvolution.

PubMed

Cheng, Shichao; Liu, Risheng; Fan, Xin; Luo, Zhongxuan

2018-05-01

Blind image deconvolution is one of the main low-level vision problems with wide applications. Many previous works manually design regularization to simultaneously estimate the latent sharp image and the blur kernel under maximum a posterior framework. However, it has been demonstrated that such joint estimation strategies may lead to the undesired trivial solution. In this paper, we present a novel perspective, using a stable feedback control system, to simulate the latent sharp image propagation. The controller of our system consists of regularization and guidance, which decide the sparsity and sharp features of latent image, respectively. Furthermore, the formational model of blind image is introduced into the feedback process to avoid the image restoration deviating from the stable point. The stability analysis of the system indicates the latent image propagation in blind deconvolution task can be efficiently estimated and controlled by cues and priors. Thus the kernel estimation used for image restoration becomes more precision. Experimental results show that our system is effective on image propagation, and can perform favorably against the state-of-the-art blind image deconvolution methods on different benchmark image sets and special blurred images. Copyright © 2018 Elsevier Ltd. All rights reserved.

Minimizing Barriers in Learning for On-Call Radiology Residents-End-to-End Web-Based Resident Feedback System.

PubMed

Choi, Hailey H; Clark, Jennifer; Jay, Ann K; Filice, Ross W

2018-02-01

Feedback is an essential part of medical training, where trainees are provided with information regarding their performance and further directions for improvement. In diagnostic radiology, feedback entails a detailed review of the differences between the residents' preliminary interpretation and the attendings' final interpretation of imaging studies. While the on-call experience of independently interpreting complex cases is important to resident education, the more traditional synchronous "read-out" or joint review is impossible due to multiple constraints. Without an efficient method to compare reports, grade discrepancies, convey salient teaching points, and view images, valuable lessons in image interpretation and report construction are lost. We developed a streamlined web-based system, including report comparison and image viewing, to minimize barriers in asynchronous communication between attending radiologists and on-call residents. Our system provides real-time, end-to-end delivery of case-specific and user-specific feedback in a streamlined, easy-to-view format. We assessed quality improvement subjectively through surveys and objectively through participation metrics. Our web-based feedback system improved user satisfaction for both attending and resident radiologists, and increased attending participation, particularly with regards to cases where substantive discrepancies were identified.

Self-referenced locking of optical coherence by single-detector electronic-frequency tagging

NASA Astrophysics Data System (ADS)

Shay, T. M.; Benham, Vincent; Spring, Justin; Ward, Benjamin; Ghebremichael, F.; Culpepper, Mark A.; Sanchez, Anthony D.; Baker, J. T.; Pilkington, D.; Berdine, Richard

2006-02-01

We report a novel coherent beam combining technique. This is the first actively phase locked optical fiber array that eliminates the need for a separate reference beam. In addition, only a single photodetector is required. The far-field central spot of the array is imaged onto the photodetector to produce the phase control loop signals. Each leg of the fiber array is phase modulated with a separate RF frequency, thus tagging the optical phase shift for each leg by a separate RF frequency. The optical phase errors for the individual array legs are separated in the electronic domain. In contrast with the previous active phase locking techniques, in our system the reference beam is spatially overlapped with all the RF modulated fiber leg beams onto a single detector. The phase shift between the optical wave in the reference leg and in the RF modulated legs is measured separately in the electronic domain and the phase error signal is feedback to the LiNbO 3 phase modulator for that leg to minimize the phase error for that leg relative to the reference leg. The advantages of this technique are 1) the elimination of the reference beam and beam combination optics and 2) the electronic separation of the phase error signals without any degradation of the phase locking accuracy. We will present the first theoretical model for self-referenced LOCSET and describe experimental results for a 3 x 3 array.

Optical fibre multi-parameter sensing with secure cloud based signal capture and processing

NASA Astrophysics Data System (ADS)

Newe, Thomas; O'Connell, Eoin; Meere, Damien; Yuan, Hongwei; Leen, Gabriel; O'Keeffe, Sinead; Lewis, Elfed

2016-05-01

Recent advancements in cloud computing technologies in the context of optical and optical fibre based systems are reported. The proliferation of real time and multi-channel based sensor systems represents significant growth in data volume. This coupled with a growing need for security presents many challenges and presents a huge opportunity for an evolutionary step in the widespread application of these sensing technologies. A tiered infrastructural system approach is adopted that is designed to facilitate the delivery of Optical Fibre-based "SENsing as a Service- SENaaS". Within this infrastructure, novel optical sensing platforms, deployed within different environments, are interfaced with a Cloud-based backbone infrastructure which facilitates the secure collection, storage and analysis of real-time data. Feedback systems, which harness this data to affect a change within the monitored location/environment/condition, are also discussed. The cloud based system presented here can also be used with chemical and physical sensors that require real-time data analysis, processing and feedback.

Counterintuitive Effects of Online Feedback in Middle School Math: Results from a Randomized Controlled Trial in ASSISTments

ERIC Educational Resources Information Center

McGuire, Patrick; Tu, Shihfen; Logue, Mary Ellin; Mason, Craig A.; Ostrow, Korinn

2017-01-01

This study compared the effects of three different feedback formats provided to sixth grade mathematics students within a web-based online learning platform, ASSISTments. A sample of 196 students were randomly assigned to one of three conditions: (1) text-based feedback; (2) image-based feedback; and (3) correctness only feedback. Regardless of…

Multicolor pyrometer for materials processing in space

NASA Technical Reports Server (NTRS)

Frish, M. B.; Frank, J.; Baker, J. E.; Foutter, R. R.; Beerman, H.; Allen, M. G.

1990-01-01

This report documents the work performed by Physical Sciences Inc. (PSI), under contract to NASA JPL, during a 2.5-year SBIR Phase 2 Program. The program goals were to design, construct, and program a prototype passive imaging pyrometer capable of measuring, as accurately as possible, and controlling the temperature distribution across the surface of a moving object suspended in space. These goals were achieved and the instrument was delivered to JPL in November 1989. The pyrometer utilizes an optical system which operates at short wavelengths compared to the peak of the black-body spectrum for the temperature range of interest, thus minimizing errors associated with a lack of knowledge about the heated sample's emissivity. To cover temperatures from 900 to 2500 K, six wavelengths are available. The preferred wavelength for measurement of a particular temperature decreases as the temperature increases. Images at all six wavelengths are projected onto a single CCD camera concurrently. The camera and optical system have been calibrated to relate the measured intensity at each pixel to the temperature of the heated object. The output of the camera is digitized by a frame grabber installed in a personal computer and analyzed automatically to yield temperature information. The data can be used in a feedback loop to alter the status of computer-activated switches and thereby control a heating system.

Optical Analogies for Teaching Physics of X-rays and CAT Scans*

NASA Astrophysics Data System (ADS)

Kalita, Spartak; Zollman, D. A.

2006-12-01

Our Modern Miracle Medical Machines project is devoted to improving motivation and performance of pre-med students in their undergraduate Physics classes. Under its framework we designed some non-traditional hands-on lab activities involving optical analogies to teach the application of contemporary physics to medical imaging. On the basis of our previous research (primarily clinical interviews with the target student population) we created activities using semi-transparent Lego blocks as analogs for understanding the image reconstruction process in computerized axial tomography (CAT or CT). Teaching interviews have been conducted with pre-med and other health-related majors using these materials. Students had to determine the shape of an object constructed of Lego blocks and hidden within a closed box. This arrangement imitated an unknown entity within a part of the human body. Using LEDs (light-emitting diodes) and a photo detector the students attempted to learn the contents of the box. They also had access to another similar Lego arrangement which they were free to open. Interviewees successfully transferred knowledge from their science and math classes (as well as from other sources) while completing activities and expressed great interest in this endeavor. Improvements to the activities have been based on the students’ feedback. *Supported by the National Science Foundation under grant 04-2675

Feedback circuit design of an auto-gating power supply for low-light-level image intensifier

NASA Astrophysics Data System (ADS)

Yang, Ye; Yan, Bo; Zhi, Qiang; Ni, Xiao-bing; Li, Jun-guo; Wang, Yu; Yao, Ze

2015-11-01

This paper introduces the basic principle of auto-gating power supply which using a hybrid automatic brightness control scheme. By the analysis of current as image intensifier to special requirements of auto-gating power supply, a feedback circuit of the auto-gating power supply is analyzed. Find out the reason of the screen flash after the auto-gating power supply assembled image intensifier. This paper designed a feedback circuit which can shorten the response time of auto-gating power supply and improve screen slight flicker phenomenon which the human eye can distinguish under the high intensity of illumination.

Airflow and optic flow mediate antennal positioning in flying honeybees

PubMed Central

Roy Khurana, Taruni; Sane, Sanjay P

2016-01-01

To maintain their speeds during navigation, insects rely on feedback from their visual and mechanosensory modalities. Although optic flow plays an essential role in speed determination, it is less reliable under conditions of low light or sparse landmarks. Under such conditions, insects rely on feedback from antennal mechanosensors but it is not clear how these inputs combine to elicit flight-related antennal behaviours. We here show that antennal movements of the honeybee, Apis mellifera, are governed by combined visual and antennal mechanosensory inputs. Frontal airflow, as experienced during forward flight, causes antennae to actively move forward as a sigmoidal function of absolute airspeed values. However, corresponding front-to-back optic flow causes antennae to move backward, as a linear function of relative optic flow, opposite the airspeed response. When combined, these inputs maintain antennal position in a state of dynamic equilibrium. DOI: http://dx.doi.org/10.7554/eLife.14449.001 PMID:27097104

Insights from a refined decomposition of cloud feedbacks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zelinka, Mark D.; Zhou, Chen; Klein, Stephen A.

Decomposing cloud feedback into components due to changes in several gross cloud properties provides valuable insights into its physical causes. Here we present a refined decomposition that separately considers changes in free tropospheric and low cloud properties, better connecting feedbacks to individual governing processes and avoiding ambiguities present in a commonly used decomposition. It reveals that three net cloud feedback components are robustly nonzero: positive feedbacks from increasing free tropospheric cloud altitude and decreasing low cloud cover and a negative feedback from increasing low cloud optical depth. Low cloud amount feedback is the dominant contributor to spread in net cloudmore » feedback but its anticorrelation with other components damps overall spread. Furthermore, the ensemble mean free tropospheric cloud altitude feedback is roughly 60% as large as the standard cloud altitude feedback because it avoids aliasing in low cloud reductions. Implications for the “null hypothesis” climate sensitivity from well-understood and robustly simulated feedbacks are discussed.« less

Insights from a refined decomposition of cloud feedbacks

DOE PAGES

Zelinka, Mark D.; Zhou, Chen; Klein, Stephen A.

2016-09-05

Decomposing cloud feedback into components due to changes in several gross cloud properties provides valuable insights into its physical causes. Here we present a refined decomposition that separately considers changes in free tropospheric and low cloud properties, better connecting feedbacks to individual governing processes and avoiding ambiguities present in a commonly used decomposition. It reveals that three net cloud feedback components are robustly nonzero: positive feedbacks from increasing free tropospheric cloud altitude and decreasing low cloud cover and a negative feedback from increasing low cloud optical depth. Low cloud amount feedback is the dominant contributor to spread in net cloudmore » feedback but its anticorrelation with other components damps overall spread. Furthermore, the ensemble mean free tropospheric cloud altitude feedback is roughly 60% as large as the standard cloud altitude feedback because it avoids aliasing in low cloud reductions. Implications for the “null hypothesis” climate sensitivity from well-understood and robustly simulated feedbacks are discussed.« less

CO.sub.2 optically pumped distributed feedback diode laser

DOEpatents

Rockwood, Stephen D.

1980-01-01

A diode laser optically pumped by a CO.sub.2 coherent source. Interference fringes generated by feeding the optical pumping beam against a second beam, periodically alter the reflectivity of the diode medium allowing frequency variation of the output signal by varying the impingent angle of the CO.sub.2 laser beams.

State-of-the-art multi-wavelength observations of nearby brightest group/cluster galaxies

NASA Astrophysics Data System (ADS)

Gendron-Marsolais, Marie-Lou; Hlavacek-Larrondo, Julie

2018-01-01

Nearby galaxy groups and clusters are crucial to our understanding of the impact of nuclear outbursts on the intracluster medium as their proximity allows us to study in detail the processes of feedback from active galactic nuclei in these systems. In this talk, I will present state-of-the-art multi-wavelength observations signatures of this mechanism.I will first show results on multi-configuration 230-470 MHz observations of the Perseus cluster from the Karl G. Jansky Very Large Array, probing the non-thermal emission from the old particle population of the AGN outflows. These observations reveal a multitude of new structures associated with the “mini-halo” and illustrate the high-quality images that can be obtained with the new JVLA at low radio-frequencies.Second, I will present new observations with the optical imaging Fourier transform spectrometer SITELLE (CFHT) of NGC 1275, the Perseus cluster's brightest galaxy. With its wide field of view, it is the only integral field unit spectroscopy instrument able to cover the large emission-line filamentary nebula in NGC 1275. I will present the first detailed velocity map of this nebula in its entirety and tackle the question of its origin (residual cooling flow or dragged gas).Finally, I will present deep Chandra observations of the nearby early-type massive elliptical galaxy NGC 4472, the most optically luminous galaxy in the local Universe, lying on the outskirts of the Virgo cluster. Enhanced X-ray rims around the radio lobes are detected and interpreted as gas uplifted from the core by the buoyant rise of the radio bubbles. We estimate the energy required to lift the gas to constitute a significant fraction of the total outburst energy.I will thus show how these high-fidelity observations of nearby brightest group/cluster galaxies are improving our understanding of the AGN feedback mechanism taking place in galaxy groups and clusters.

A new visual feedback-based magnetorheological haptic master for robot-assisted minimally invasive surgery

NASA Astrophysics Data System (ADS)

Choi, Seung-Hyun; Kim, Soomin; Kim, Pyunghwa; Park, Jinhyuk; Choi, Seung-Bok

2015-06-01

In this study, we developed a novel four-degrees-of-freedom haptic master using controllable magnetorheological (MR) fluid. We also integrated the haptic master with a vision device with image processing for robot-assisted minimally invasive surgery (RMIS). The proposed master can be used in RMIS as a haptic interface to provide the surgeon with a sense of touch by using both kinetic and kinesthetic information. The slave robot, which is manipulated with a proportional-integrative-derivative controller, uses a force sensor to obtain the desired forces from tissue contact, and these desired repulsive forces are then embodied through the MR haptic master. To verify the effectiveness of the haptic master, the desired force and actual force are compared in the time domain. In addition, a visual feedback system is implemented in the RMIS experiment to distinguish between the tumor and organ more clearly and provide better visibility to the operator. The hue-saturation-value color space is adopted for the image processing since it is often more intuitive than other color spaces. The image processing and haptic feedback are realized on surgery performance. In this work, tumor-cutting experiments are conducted under four different operating conditions: haptic feedback on, haptic feedback off, image processing on, and image processing off. The experimental realization shows that the performance index, which is a function of pixels, is different in the four operating conditions.

Effect of injection current and temperature on signal strength in a laser diode optical feedback interferometer.

PubMed

Al Roumy, Jalal; Perchoux, Julien; Lim, Yah Leng; Taimre, Thomas; Rakić, Aleksandar D; Bosch, Thierry

2015-01-10

We present a simple analytical model that describes the injection current and temperature dependence of optical feedback interferometry signal strength for a single-mode laser diode. The model is derived from the Lang and Kobayashi rate equations, and is developed both for signals acquired from the monitoring photodiode (proportional to the variations in optical power) and for those obtained by amplification of the corresponding variations in laser voltage. The model shows that both the photodiode and the voltage signal strengths are dependent on the laser slope efficiency, which itself is a function of the injection current and the temperature. Moreover, the model predicts that the photodiode and voltage signal strengths depend differently on injection current and temperature. This important model prediction was proven experimentally for a near-infrared distributed feedback laser by measuring both types of signals over a wide range of injection currents and temperatures. Therefore, this simple model provides important insight into the radically different biasing strategies required to achieve optimal sensor sensitivity for both interferometric signal acquisition schemes.

A New Feedback-Based Method for Parameter Adaptation in Image Processing Routines.

PubMed

Khan, Arif Ul Maula; Mikut, Ralf; Reischl, Markus

2016-01-01

The parametrization of automatic image processing routines is time-consuming if a lot of image processing parameters are involved. An expert can tune parameters sequentially to get desired results. This may not be productive for applications with difficult image analysis tasks, e.g. when high noise and shading levels in an image are present or images vary in their characteristics due to different acquisition conditions. Parameters are required to be tuned simultaneously. We propose a framework to improve standard image segmentation methods by using feedback-based automatic parameter adaptation. Moreover, we compare algorithms by implementing them in a feedforward fashion and then adapting their parameters. This comparison is proposed to be evaluated by a benchmark data set that contains challenging image distortions in an increasing fashion. This promptly enables us to compare different standard image segmentation algorithms in a feedback vs. feedforward implementation by evaluating their segmentation quality and robustness. We also propose an efficient way of performing automatic image analysis when only abstract ground truth is present. Such a framework evaluates robustness of different image processing pipelines using a graded data set. This is useful for both end-users and experts.

A New Feedback-Based Method for Parameter Adaptation in Image Processing Routines

PubMed Central

Mikut, Ralf; Reischl, Markus

2016-01-01

The parametrization of automatic image processing routines is time-consuming if a lot of image processing parameters are involved. An expert can tune parameters sequentially to get desired results. This may not be productive for applications with difficult image analysis tasks, e.g. when high noise and shading levels in an image are present or images vary in their characteristics due to different acquisition conditions. Parameters are required to be tuned simultaneously. We propose a framework to improve standard image segmentation methods by using feedback-based automatic parameter adaptation. Moreover, we compare algorithms by implementing them in a feedforward fashion and then adapting their parameters. This comparison is proposed to be evaluated by a benchmark data set that contains challenging image distortions in an increasing fashion. This promptly enables us to compare different standard image segmentation algorithms in a feedback vs. feedforward implementation by evaluating their segmentation quality and robustness. We also propose an efficient way of performing automatic image analysis when only abstract ground truth is present. Such a framework evaluates robustness of different image processing pipelines using a graded data set. This is useful for both end-users and experts. PMID:27764213

Centralized automated quality assurance for large scale health care systems. A pilot method for some aspects of dental radiography.

PubMed

Benn, D K; Minden, N J; Pettigrew, J C; Shim, M

1994-08-01

President Clinton's Health Security Act proposes the formation of large scale health plans with improved quality assurance. Dental radiography consumes 4% ($1.2 billion in 1990) of total dental expenditure yet regular systematic office quality assurance is not performed. A pilot automated method is described for assessing density of exposed film and fogging of unexposed processed film. A workstation and camera were used to input intraoral radiographs. Test images were produced from a phantom jaw with increasing exposure times. Two radiologists subjectively classified the images as too light, acceptable, or too dark. A computer program automatically classified global grey level histograms from the test images as too light, acceptable, or too dark. The program correctly classified 95% of 88 clinical films. Optical density of unexposed film in the range 0.15 to 0.52 measured by computer was reliable to better than 0.01. Further work is needed to see if comprehensive centralized automated radiographic quality assurance systems with feedback to dentists are feasible, are able to improve quality, and are significantly cheaper than conventional clerical methods.

Method for enhanced control of welding processes

DOEpatents

Sheaffer, Donald A.; Renzi, Ronald F.; Tung, David M.; Schroder, Kevin

2000-01-01

Method and system for producing high quality welds in welding processes, in general, and gas tungsten arc (GTA) welding, in particular by controlling weld penetration. Light emitted from a weld pool is collected from the backside of a workpiece by optical means during welding and transmitted to a digital video camera for further processing, after the emitted light is first passed through a short wavelength pass filter to remove infrared radiation. By filtering out the infrared component of the light emitted from the backside weld pool image, the present invention provides for the accurate determination of the weld pool boundary. Data from the digital camera is fed to an imaging board which focuses on a 100.times.100 pixel portion of the image. The board performs a thresholding operation and provides this information to a digital signal processor to compute the backside weld pool dimensions and area. This information is used by a control system, in a dynamic feedback mode, to automatically adjust appropriate parameters of a welding system, such as the welding current, to control weld penetration and thus, create a uniform weld bead and high quality weld.

Reset noise suppression in two-dimensional CMOS photodiode pixels through column-based feedback-reset

NASA Technical Reports Server (NTRS)

Pain, B.; Cunningham, T. J.; Hancock, B.; Yang, G.; Seshadri, S.; Ortiz, M.

2002-01-01

We present new CMOS photodiode imager pixel with ultra-low read noise through on-chip suppression of reset noise via column-based feedback circuitry. The noise reduction is achieved without introducing any image lag, and with insignificant reduction in quantum efficiency and full well.

Closed-loop motor control using high-speed fiber optics

NASA Technical Reports Server (NTRS)

Dawson, Reginald (Inventor); Rodriquiz, Dagobert (Inventor)

1991-01-01

A closed-loop control system for controlling the operation of one or more servo motors or other controllable devices is described. The system employs a fiber optics link immune to electromagnetic interference, for transmission of control signals from a controller or controllers at a remote station to the power electronics located in proximity to the motors or other devices at the local station. At the remote station the electrical control signals are time-multiplexed, converted to a formatted serial bit stream, and converted to light signals for transmission over a single fiber of the fiber optics link. At the local station, the received optical signals are reconstructed as electrical control signals for the controlled motors or other devices. At the local station, an encoder sensor linked to the driven device generates encoded feedback signals which provide information as to a condition of the controlled device. The encoded signals are placed in a formatted serial bit stream, multiplexed, and transmitted as optical signals over a second fiber of the fiber optic link which closes the control loop of the closed-loop motor controller. The encoded optical signals received at the remote station are demultiplexed, reconstructed and coupled to the controller(s) as electrical feedback signals.

All-Fiber Configuration Laser Self-Mixing Doppler Velocimeter Based on Distributed Feedback Fiber Laser.

PubMed

Wu, Shuang; Wang, Dehui; Xiang, Rong; Zhou, Junfeng; Ma, Yangcheng; Gui, Huaqiao; Liu, Jianguo; Wang, Huanqin; Lu, Liang; Yu, Benli

2016-07-27

In this paper, a novel velocimeter based on laser self-mixing Doppler technology has been developed for speed measurement. The laser employed in our experiment is a distributed feedback (DFB) fiber laser, which is an all-fiber structure using only one Fiber Bragg Grating to realize optical feedback and wavelength selection. Self-mixing interference for optical velocity sensing is experimentally investigated in this novel system, and the experimental results show that the Doppler frequency is linearly proportional to the velocity of a moving target, which agrees with the theoretical analysis commendably. In our experimental system, the velocity measurement can be achieved in the range of 3.58 mm/s-2216 mm/s with a relative error under one percent, demonstrating that our novel all-fiber configuration velocimeter can implement wide-range velocity measurements with high accuracy.

Pattern formation in a liquid-crystal light valve with feedback, including polarization, saturation, and internal threshold effects

NASA Astrophysics Data System (ADS)

Neubecker, R.; Oppo, G.-L.; Thuering, B.; Tschudi, T.

1995-07-01

The use of liquid-crystal light valves (LCLV's) as nonlinear elements in diffractive optical systems with feedback leads to the formation of a variety of optical patterns. The spectrum of possible spatial instabilities is shown to be even richer when the LCLV's capability for polarization modulation is utilized and internal threshold and saturation effects are considered. We derive a model for the feedback system based on a realistic description of the LCLV's internal function and coupling to a polarizer. Thresholds of pattern formation are compared to the common Kerr-type approximation and show transitions involving rolls, squares, hexagons, and tiled patterns. Numerical and experimental results confirm our theoretical predictions and unveil how patterns and their typical length scales can be easily controlled by changes of the parameters.

Delay feedback induces a spontaneous motion of two-dimensional cavity solitons in driven semiconductor microcavities

NASA Astrophysics Data System (ADS)

Tlidi, M.; Averlant, E.; Vladimirov, A.; Panajotov, K.

2012-09-01

We consider a broad area vertical-cavity surface-emitting laser (VCSEL) operating below the lasing threshold and subject to optical injection and time-delayed feedback. We derive a generalized delayed Swift-Hohenberg equation for the VCSEL system, which is valid close to the nascent optical bistability. We first characterize the stationary-cavity solitons by constructing their snaking bifurcation diagram and by showing clustering behavior within the pinning region of parameters. Then, we show that the delayed feedback induces a spontaneous motion of two-dimensional (2D) cavity solitons in an arbitrary direction in the transverse plane. We characterize moving cavity solitons by estimating their threshold and calculating their velocity. Numerical 2D solutions of the governing semiconductor laser equations are in close agreement with those obtained from the delayed generalized Swift-Hohenberg equation.

Swept-frequency feedback interferometry using terahertz frequency QCLs: a method for imaging and materials analysis.

PubMed

Rakić, Aleksandar D; Taimre, Thomas; Bertling, Karl; Lim, Yah Leng; Dean, Paul; Indjin, Dragan; Ikonić, Zoran; Harrison, Paul; Valavanis, Alexander; Khanna, Suraj P; Lachab, Mohammad; Wilson, Stephen J; Linfield, Edmund H; Davies, A Giles

2013-09-23

The terahertz (THz) frequency quantum cascade laser (QCL) is a compact source of high-power radiation with a narrow intrinsic linewidth. As such, THz QCLs are extremely promising sources for applications including high-resolution spectroscopy, heterodyne detection, and coherent imaging. We exploit the remarkable phase-stability of THz QCLs to create a coherent swept-frequency delayed self-homodyning method for both imaging and materials analysis, using laser feedback interferometry. Using our scheme we obtain amplitude-like and phase-like images with minimal signal processing. We determine the physical relationship between the operating parameters of the laser under feedback and the complex refractive index of the target and demonstrate that this coherent detection method enables extraction of complex refractive indices with high accuracy. This establishes an ultimately compact and easy-to-implement THz imaging and materials analysis system, in which the local oscillator, mixer, and detector are all combined into a single laser.

Mesoscale modeling of smoke radiative feedback over the Sahel region

NASA Astrophysics Data System (ADS)

Yang, Z.; Wang, J.; Ichoku, C. M.; Ellison, L.; Zhang, F.; Yue, Y.

2013-12-01

This study employs satellite observations and a fully-coupled meteorology-chemistry-aerosol model, Weather Research and Forecasting model with Chemistry (WRF-Chem) to study the smoke radative feedback on surface energy budget, boundary layer processes, and atmospheric lapse rate in February 2008 over the Sahel region. The smoke emission inventories we use come from various sources, including but not limited to the Fire Locating and Modeling of Burning Emissions (FLAMBE) developed by NRL and the Fire Energetic and Emissions Research (FEER) developed by NASA GSFC. Model performance is evaluated using numerous satellite and ground-based datasets: MODIS true color images, ground-based Aerosol Optical Depth (AOD) measurements from AERONET, MODIS AOD retrievals, and Cloud-Aerosol Lidar data with Orthogonal Polarization (CALIOP) atmospheric backscattering and extinction products. Specification of smoke injection height of 650 m in WRF-Chem yields aerosol vertical profiles that are most consistent with CALIOP observations of aerosol layer height. Statistically, 5% of the CALIPSO valid measurements of aerosols in February 2008 show aerosol layers either above the clouds or between the clouds, reinforcing the importance of the aerosol vertical distribution for quantifying aerosol impact on climate in the Sahel region. The results further show that the smoke radiative feedbacks are sensitive to assumptions of black carbon and organic carbon ratio in the particle emission inventory. Also investigated is the smoke semi-direct effect as a function of cloud fraction.

Chaotic optical time-domain reflectometry using a distributed feedback laser diode modulated by an improved Colpitts oscillator

NASA Astrophysics Data System (ADS)

Li, Jing Xia; Xu, Hang; Liu, Li; Su, Peng Cheng; Zhang, Jian Guo

2015-05-01

We report a chaotic optical time-domain reflectometry for fiber fault location, where a chaotic probe signal is generated by driving a distributed feedback laser diode with an improved Colpitts chaotic oscillator. The results show that the unterminated fiber end, the loose connector, and the mismatch connector can be precisely located. A measurement range of approximately 91 km and a range independent resolution of 6 cm are achieved. This implementation method is easy to integrate and is cost effective, which gives it great potential for commercial applications.

Negative Avalanche Feedback Detectors for Photon-Counting Optical Communications

NASA Technical Reports Server (NTRS)

Farr, William H.

2009-01-01

Negative Avalanche Feedback photon counting detectors with near-infrared spectral sensitivity offer an alternative to conventional Geiger mode avalanche photodiode or phototube detectors for free space communications links at 1 and 1.55 microns. These devices demonstrate linear mode photon counting without requiring any external reset circuitry and may even be operated at room temperature. We have now characterized the detection efficiency, dark count rate, after-pulsing, and single photon jitter for three variants of this new detector class, as well as operated these uniquely simple to use devices in actual photon starved free space optical communications links.

Data and image transfer using mobile phones to strengthen microscopy-based diagnostic services in low and middle income country laboratories.

PubMed

Tuijn, Coosje J; Hoefman, Bas J; van Beijma, Hajo; Oskam, Linda; Chevrollier, Nicolas

2011-01-01

The emerging market of mobile phone technology and its use in the health sector is rapidly expanding and connecting even the most remote areas of world. Distributing diagnostic images over the mobile network for knowledge sharing, feedback or quality control is a logical innovation. To determine the feasibility of using mobile phones for capturing microscopy images and transferring these to a central database for assessment, feedback and educational purposes. A feasibility study was carried out in Uganda. Images of microscopy samples were taken using a prototype connector that could fix a variety of mobile phones to a microscope. An Information Technology (IT) platform was set up for data transfer from a mobile phone to a website, including feedback by text messaging to the end user. Clear images were captured using mobile phone cameras of 2 megapixels (MP) up to 5MP. Images were sent by mobile Internet to a website where they were visualized and feedback could be provided to the sender by means of text message. The process of capturing microscopy images on mobile phones, relaying them to a central review website and feeding back to the sender is feasible and of potential benefit in resource poor settings. Even though the system needs further optimization, it became evident from discussions with stakeholders that there is a demand for this type of technology.

Construction of a Visible Diode Laser Source for Free Radical Photochemistry and Spectroscopy Experiments

NASA Technical Reports Server (NTRS)

Newman, Bronjelyn; Halpern, Joshua B.

1997-01-01

Tunable diode lasers are reliable sources of narrow-band light and comparatively cheap. Optical feedback simplifies frequency tuning of the laser diodes. We are building an inexpensive diode laser system incorporating optical feedback from a diffraction grating. The external optical cavity can be used with lasers that emit between 2 and 100 mW, and will also work if they are pulsed, although this will significantly degrade the bandwidth. The diode laser output power and bandwidth are comparable to CW dye lasers used in kinetics and dynamics experiments. However, their cost and maintenance will be much less as will alignment time. We intend to use the diode lasers to investigate CN and C2 kinetics as well as to study dissociation dynamics of atmospherically important molecules.

Iterative color-multiplexed, electro-optical processor.

PubMed

Psaltis, D; Casasent, D; Carlotto, M

1979-11-01

A noncoherent optical vector-matrix multiplier using a linear LED source array and a linear P-I-N photodiode detector array has been combined with a 1-D adder in a feedback loop. The resultant iterative optical processor and its use in solving simultaneous linear equations are described. Operation on complex data is provided by a novel color-multiplexing system.

Prototype tactile feedback system for examination by skin touch.

PubMed

Lee, O; Lee, K; Oh, C; Kim, K; Kim, M

2014-08-01

Diagnosis of conditions such as psoriasis and atopic dermatitis, in the case of induration, involves palpating the infected area via hands and then selecting a ratings score. However, the score is determined based on the tester's experience and standards, making it subjective. To provide tactile feedback on the skin, we developed a prototype tactile feedback system to simulate skin wrinkles with PHANToM OMNI. To provide the user with tactile feedback on skin wrinkles, a visual and haptic Augmented Reality system was developed. First, a pair of stereo skin images obtained by a stereo camera generates a disparity map of skin wrinkles. Second, the generated disparity map is sent to an implemented tactile rendering algorithm that computes a reaction force according to the user's interaction with the skin image. We first obtained a stereo image of skin wrinkles from the in vivo stereo imaging system, which has a baseline of 50.8 μm, and obtained the disparity map with a graph cuts algorithm. The left image is displayed on the monitor to enable the user to recognize the location visually. The disparity map of the skin wrinkle image sends skin wrinkle information as a tactile response to the user through a haptic device. We successfully developed a tactile feedback system for virtual skin wrinkle simulation by means of a commercialized haptic device that provides the user with a single point of contact to feel the surface roughness of a virtual skin sample. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Semi-automatic feedback using concurrence between mixture vectors for general databases

NASA Astrophysics Data System (ADS)

Larabi, Mohamed-Chaker; Richard, Noel; Colot, Olivier; Fernandez-Maloigne, Christine

2001-12-01

This paper describes how a query system can exploit the basic knowledge by employing semi-automatic relevance feedback to refine queries and runtimes. For general databases, it is often useless to call complex attributes, because we have not sufficient information about images in the database. Moreover, these images can be topologically very different from one to each other and an attribute that is powerful for a database category may be very powerless for the other categories. The idea is to use very simple features, such as color histogram, correlograms, Color Coherence Vectors (CCV), to fill out the signature vector. Then, a number of mixture vectors is prepared depending on the number of very distinctive categories in the database. Knowing that a mixture vector is a vector containing the weight of each attribute that will be used to compute a similarity distance. We post a query in the database using successively all the mixture vectors defined previously. We retain then the N first images for each vector in order to make a mapping using the following information: Is image I present in several mixture vectors results? What is its rank in the results? These informations allow us to switch the system on an unsupervised relevance feedback or user's feedback (supervised feedback).

Feedback of personal retinal images appears to have a motivational impact in people with non-proliferative diabetic retinopathy and suboptimal HbA1c: findings of a pilot study.

PubMed

Rees, G; Lamoureux, E L; Nicolaou, T E; Hodgson, L A B; Weinman, J; Speight, J

2013-09-01

To conduct a pilot study to explore the potential impact of visual feedback of personal retinal images on diabetes outcomes. Twenty-five participants with non-proliferative diabetic retinopathy and suboptimal HbA(1c) (> 53 mmol/mol; > 7%) were randomized to receive visual feedback of their own retinal images or to a control group. At baseline and 3-month follow-up, HbA(1c), standard measures of beliefs, diabetes-related distress and self-care activities were assessed. In unadjusted models, relative to controls, the intervention group showed significantly greater improvement in HbA(1c) at 3-month follow-up (-0.6% vs. +0.3%, P < 0.01), as well as enhanced motivation to improve blood glucose management (P < 0.05). This small pilot study provides preliminary evidence that visual feedback of personal retinal images may offer a practical educational strategy for clinicians in eye care services to improve diabetes outcomes in non-target compliant patients. A fully powered randomized controlled trial is required to confirm these findings and determine the optimal use of feedback to produce sustained effects. © 2013 The Authors. Diabetic Medicine © 2013 Diabetes UK.

Optical processing furnace with quartz muffle and diffuser plate

DOEpatents

Sopori, B.L.

1996-11-19

An optical furnace for annealing a process wafer is disclosed comprising a source of optical energy, a quartz muffle having a door to hold the wafer for processing, and a quartz diffuser plate to diffuse the light impinging on the quartz muffle; a feedback system with a light sensor located in the wall of the muffle is also provided for controlling the source of optical energy. 5 figs.

Automatic Gain Control in Compact Spectrometers.

PubMed

Protopopov, Vladimir

2016-03-01

An image intensifier installed in the optical path of a compact spectrometer may act not only as a fast gating unit, which is widely used for time-resolved measurements, but also as a variable attenuator-amplifier in a continuous wave mode. This opens the possibility of an automatic gain control, a new feature in spectroscopy. With it, the user is relieved from the necessity to manually adjust signal level at a certain value that it is done automatically by means of an electronic feedback loop. It is even more important that automatic gain control is done without changing exposure time, which is an additional benefit in time-resolved experiments. The concept, algorithm, design considerations, and experimental results are presented. © The Author(s) 2016.

Nike Facility Diagnostics and Data Acquisition System

NASA Astrophysics Data System (ADS)

Chan, Yung; Aglitskiy, Yefim; Karasik, Max; Kehne, David; Obenschain, Steve; Oh, Jaechul; Serlin, Victor; Weaver, Jim

2013-10-01

The Nike laser-target facility is a 56-beam krypton fluoride system that can deliver 2 to 3 kJ of laser energy at 248 nm onto targets inside a two meter diameter vacuum chamber. Nike is used to study physics and technology issues related to laser direct-drive ICF fusion, including hydrodynamic and laser-plasma instabilities, material behavior at extreme pressures, and optical and x-ray diagnostics for laser-heated targets. A suite of laser and target diagnostics are fielded on the Nike facility, including high-speed, high-resolution x-ray and visible imaging cameras, spectrometers and photo-detectors. A centrally-controlled, distributed computerized data acquisition system provides robust data management and near real-time analysis feedback capability during target shots. Work supported by DOE/NNSA.

Wavefront Control and Image Restoration with Less Computing

NASA Technical Reports Server (NTRS)

Lyon, Richard G.

2010-01-01

PseudoDiversity is a method of recovering the wavefront in a sparse- or segmented- aperture optical system typified by an interferometer or a telescope equipped with an adaptive primary mirror consisting of controllably slightly moveable segments. (PseudoDiversity should not be confused with a radio-antenna-arraying method called pseudodiversity.) As in the cases of other wavefront- recovery methods, the streams of wavefront data generated by means of PseudoDiversity are used as feedback signals for controlling electromechanical actuators of the various segments so as to correct wavefront errors and thereby, for example, obtain a clearer, steadier image of a distant object in the presence of atmospheric turbulence. There are numerous potential applications in astronomy, remote sensing from aircraft and spacecraft, targeting missiles, sighting military targets, and medical imaging (including microscopy) through such intervening media as cells or water. In comparison with prior wavefront-recovery methods used in adaptive optics, PseudoDiversity involves considerably simpler equipment and procedures and less computation. For PseudoDiversity, there is no need to install separate metrological equipment or to use any optomechanical components beyond those that are already parts of the optical system to which the method is applied. In Pseudo- Diversity, the actuators of a subset of the segments or subapertures are driven to make the segments dither in the piston, tilt, and tip degrees of freedom. Each aperture is dithered at a unique frequency at an amplitude of a half wavelength of light. During the dithering, images on the focal plane are detected and digitized at a rate of at least four samples per dither period. In the processing of the image samples, the use of different dither frequencies makes it possible to determine the separate effects of the various dithered segments or apertures. The digitized image-detector outputs are processed in the spatial-frequency (Fourier-transform) domain to obtain measures of the piston, tip, and tilt errors over each segment or subaperture. Once these measures are known, they are fed back to the actuators to correct the errors. In addition, measures of errors that remain after correction by use of the actuators are further utilized in an algorithm in which the image is phase-corrected in the spatial-frequency domain and then transformed back to the spatial domain at each time step and summed with the images from all previous time steps to obtain a final image having a greater signal-to-noise ratio (and, hence, a visual quality) higher than would otherwise be attainable.

Improving Clinical Feedback to Anesthesia Residents by Using an Optical Scanner and a Microcomputer.

ERIC Educational Resources Information Center

Albanese, Mark A.; And Others

1989-01-01

At the University of Iowa problems associated with managing evaluations of anesthesia residents led to a major backlog of unanalyzed evaluation forms. A system developed at the University that enables ongoing feedback to residents and provides a method to assess the clinical competence of residents is described. (Author/MLW)

Effects of OCR Errors on Ranking and Feedback Using the Vector Space Model.

ERIC Educational Resources Information Center

Taghva, Kazem; And Others

1996-01-01

Reports on the performance of the vector space model in the presence of OCR (optical character recognition) errors in information retrieval. Highlights include precision and recall, a full-text test collection, smart vector representation, impact of weighting parameters, ranking variability, and the effect of relevance feedback. (Author/LRW)

An integrated optical sensor for GMAW feedback control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, P.L.; Watkins, A.D.; Larsen, E.D.

1992-08-01

The integrated optical sensor (IOS) is a multifunction feedback control sensor for arc welding, that is computer automated and independent of significant operator interaction. It is based on three major ``off-the-shelf`` components: a charged coupled device (CCD) camera, a diode laser, and a processing computer. The sensor head is compact and lightweight to avoid interference with weld head mobility, hardened to survive the harsh operating environment, and free of specialized cooling and power requirements. The sensor is positioned behind the GMAW torch and measures weld pool position and width, standoff distance, and postweld centerline cooling rate. Weld pool position andmore » width are used in a feedback loop, by the weld controller, to track the weld pool relative to the weld joint, thus allowing compensation for such phenomena as arc blow. Sensor stand off distance is used in a feedback loop to control the contact tip to base metal distance during the welding process. Cooling rate information is used to infer the final metallurgical state of the weld bead and heat affected zone, thereby providing a means of controlling post weld mechanical properties.« less

An integrated optical sensor for GMAW feedback control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, P.L.; Watkins, A.D.; Larsen, E.D.

1992-01-01

The integrated optical sensor (IOS) is a multifunction feedback control sensor for arc welding, that is computer automated and independent of significant operator interaction. It is based on three major off-the-shelf'' components: a charged coupled device (CCD) camera, a diode laser, and a processing computer. The sensor head is compact and lightweight to avoid interference with weld head mobility, hardened to survive the harsh operating environment, and free of specialized cooling and power requirements. The sensor is positioned behind the GMAW torch and measures weld pool position and width, standoff distance, and postweld centerline cooling rate. Weld pool position andmore » width are used in a feedback loop, by the weld controller, to track the weld pool relative to the weld joint, thus allowing compensation for such phenomena as arc blow. Sensor stand off distance is used in a feedback loop to control the contact tip to base metal distance during the welding process. Cooling rate information is used to infer the final metallurgical state of the weld bead and heat affected zone, thereby providing a means of controlling post weld mechanical properties.« less

An optical-density-based feedback feeding method for ammonium concentration control in Spirulina platensis cultivation.

PubMed

Bao, Yilu; Wen, Shumei; Cong, Wei; Wu, Xia; Ning, Zhengxiang

2012-07-01

Cultivation of Spirulina platensis using ammonium salts or wastewater containing ammonium as alternative nitrogen sources is considered as a commercial way to reduce the production cost. In this research, by analyzing the relationship between biomass production and ammonium- N consumption in the fed-batch culture of Spirulina platensis using ammonium bicarbonate as a nitrogen nutrient source, an online adaptive control strategy based on optical density (OD) measurements for controlling ammonium feeding was presented. The ammonium concentration was successfully controlled between the cell growth inhibitory and limiting concentrations using this OD-based feedback feeding method. As a result, the maximum biomass concentration (2.98 g/l), productivity (0.237 g/l·d), nitrogen-to-cell conversion factor (7.32 gX/gN), and contents of protein (64.1%) and chlorophyll (13.4 mg/g) obtained by using the OD-based feedback feeding method were higher than those using the constant and variable feeding methods. The OD-based feedback feeding method could be recognized as an applicable way to control ammonium feeding and a benefit for Spirulina platensis cultivations.

Force estimation from OCT volumes using 3D CNNs.

PubMed

Gessert, Nils; Beringhoff, Jens; Otte, Christoph; Schlaefer, Alexander

2018-07-01

Estimating the interaction forces of instruments and tissue is of interest, particularly to provide haptic feedback during robot-assisted minimally invasive interventions. Different approaches based on external and integrated force sensors have been proposed. These are hampered by friction, sensor size, and sterilizability. We investigate a novel approach to estimate the force vector directly from optical coherence tomography image volumes. We introduce a novel Siamese 3D CNN architecture. The network takes an undeformed reference volume and a deformed sample volume as an input and outputs the three components of the force vector. We employ a deep residual architecture with bottlenecks for increased efficiency. We compare the Siamese approach to methods using difference volumes and two-dimensional projections. Data were generated using a robotic setup to obtain ground-truth force vectors for silicon tissue phantoms as well as porcine tissue. Our method achieves a mean average error of [Formula: see text] when estimating the force vector. Our novel Siamese 3D CNN architecture outperforms single-path methods that achieve a mean average error of [Formula: see text]. Moreover, the use of volume data leads to significantly higher performance compared to processing only surface information which achieves a mean average error of [Formula: see text]. Based on the tissue dataset, our methods shows good generalization in between different subjects. We propose a novel image-based force estimation method using optical coherence tomography. We illustrate that capturing the deformation of subsurface structures substantially improves force estimation. Our approach can provide accurate force estimates in surgical setups when using intraoperative optical coherence tomography.

Roughness based perceptual analysis towards digital skin imaging system with haptic feedback.

PubMed

Kim, K

2016-08-01

To examine psoriasis or atopic eczema, analyzing skin roughness by palpation is essential to precisely diagnose skin diseases. However, optical sensor based skin imaging systems do not allow dermatologists to touch skin images. To solve the problem, a new haptic rendering technology that can accurately display skin roughness must be developed. In addition, the rendering algorithm must be able to filter spatial noises created during 2D to 3D image conversion without losing the original roughness on the skin image. In this study, a perceptual way to design a noise filter that will remove spatial noises and in the meantime recover maximized roughness is introduced by understanding human sensitivity on surface roughness. A visuohaptic rendering system that can provide a user with seeing and touching digital skin surface roughness has been developed including a geometric roughness estimation method from a meshed surface. In following, a psychophysical experiment was designed and conducted with 12 human subjects to measure human perception with the developed visual and haptic interfaces to examine surface roughness. From the psychophysical experiment, it was found that touch is more sensitive at lower surface roughness, and vice versa. Human perception with both senses, vision and touch, becomes less sensitive to surface distortions as roughness increases. When interact with both channels, visual and haptic interfaces, the performance to detect abnormalities on roughness is greatly improved by sensory integration with the developed visuohaptic rendering system. The result can be used as a guideline to design a noise filter that can perceptually remove spatial noises while recover maximized roughness values from a digital skin image obtained by optical sensors. In addition, the result also confirms that the developed visuohaptic rendering system can help dermatologists or skin care professionals examine skin conditions by using vision and touch at the same time. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

AXIS - A High Angular Resoltuion X-ray Probe Concept Study

NASA Astrophysics Data System (ADS)

Mushotzky, Richard; AXIS Study Team

2018-01-01

AXIS is a probe-class concept under study to the 2020 Decadal survey. AXIS will extend and enhance the science of high angular resolution x-ray imaging and spectroscopy in the next decade with ~0.3" angular resolution over a 7' radius field of view and an order of magnitude more collecting area than Chandra in the 0.3-12 keV band with a cost consistent with a probe.These capabilities enable major advances in a wide range of science such as: (1) measuring the event horizon scale structure in AGN accretion disks and the spins of supermassive black holes through observations of gravitationally-microlensed quasars; (ii) determining AGN and starburst feedback in galaxies and galaxy clusters through direct imaging of winds and interaction of jets and via spatially resolved imaging of galaxies at high-z; (iii) fueling of AGN by probing the Bondi radius of over 20 nearby galaxies; (iv) hierarchical structure formation and the SMBH merger rate through measurement of the occurrence rate of dual AGN and occupation fraction of SMBHs; (v) advancing SNR physics and galaxy ecology through large detailed samples of SNR in nearby galaxies; (vi) measuring the Cosmic Web through its connection to cluster outskirts. With a nominal 2028 launch, AXIS benefits from natural synergies with the ELTs, LSST, ALMA, WFIRST and ATHENA. AXIS utilizes breakthroughs in the construction of lightweight X-ray optics from mono-crystalline silicon blocks, and developments in the fabrication of large format, small pixel, high readout rate detectors allowing a robust and cost effective design. The AXIS team welcomes input and feedback from the community in preparation for the 2020 Decadal review.

All-Fiber Configuration Laser Self-Mixing Doppler Velocimeter Based on Distributed Feedback Fiber Laser

PubMed Central

Wu, Shuang; Wang, Dehui; Xiang, Rong; Zhou, Junfeng; Ma, Yangcheng; Gui, Huaqiao; Liu, Jianguo; Wang, Huanqin; Lu, Liang; Yu, Benli

2016-01-01

In this paper, a novel velocimeter based on laser self-mixing Doppler technology has been developed for speed measurement. The laser employed in our experiment is a distributed feedback (DFB) fiber laser, which is an all-fiber structure using only one Fiber Bragg Grating to realize optical feedback and wavelength selection. Self-mixing interference for optical velocity sensing is experimentally investigated in this novel system, and the experimental results show that the Doppler frequency is linearly proportional to the velocity of a moving target, which agrees with the theoretical analysis commendably. In our experimental system, the velocity measurement can be achieved in the range of 3.58 mm/s–2216 mm/s with a relative error under one percent, demonstrating that our novel all-fiber configuration velocimeter can implement wide-range velocity measurements with high accuracy. PMID:27472342

Aspheric figure generation using feedback from an infrared phase-shifting interferometer

NASA Astrophysics Data System (ADS)

Stahl, H. P.; Ketelsen, D.

An infrared phase-shifting interferometric system has been integrated with a novel optical figure generator at the University of Arizona Optical Sciences Center. This unique generator facility can produce generalized axially symmetric surface figures in a timely and cost-effective manner. The success of this facility depends on both its ability to efficiently remove material while forming the surface figure, and its ability to monitor the surface figure during the generation process to provide feedback to the optician. The facility has been used on several occasions to custom-generate off-axis parabolic segments. Figures to within 0.30 microns rms of the desired figure have been obtained. This paper discusses the usefulness of the infrared phase-shifting interferometric system for providing figure correcting feedback to the optician during the generation of the off-axis parabolic segments, and how it is affected by the surface roughness produced by each generator tool.

International Congress on High-Speed Photography and Photonics, 19th, Cambridge, England, Sept. 16-21, 1990, Proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garfield, B.R.; Rendell, J.T.

1991-01-01

The present conference discusses the application of schlieren photography in industry, laser fiber-optic high speed photography, holographic visualization of hypervelocity explosions, sub-100-picosec X-ray grating cameras, flash soft X-radiography, a novel approach to synchroballistic photography, a programmable image converter framing camera, high speed readout CCDs, an ultrafast optomechanical camera, a femtosec streak tube, a modular streak camera for laser ranging, and human-movement analysis with real-time imaging. Also discussed are high-speed photography of high-resolution moire patterns, a 2D electron-bombarded CCD readout for picosec electrooptical data, laser-generated plasma X-ray diagnostics, 3D shape restoration with virtual grating phase detection, Cu vapor lasers for highmore » speed photography, a two-frequency picosec laser with electrooptical feedback, the conversion of schlieren systems to high speed interferometers, laser-induced cavitation bubbles, stereo holographic cinematography, a gatable photonic detector, and laser generation of Stoneley waves at liquid-solid boundaries.« less

Creating Feedback Channels With Optical Communications For Information Operations (IO)

DTIC Science & Technology

2016-06-01

amphibious operations. Optical communications technologies, direct marketing principles , and current IO shortfalls are explored to determine whether...technology. First, these concepts are applied to show covert amphibious operations. Optical communications technologies, direct marketing principles , and...power, as per Appendix A. A major portion of the marketing campaign comes in the form of advertising. The correlating principles of advertising in

Through-wafer optical probe characterization for microelectromechanical systems positional state monitoring and feedback control

NASA Astrophysics Data System (ADS)

Dawson, Jeremy M.; Chen, Jingdong; Brown, Kolin S.; Famouri, Parviz F.; Hornak, Lawrence A.

2000-12-01

Implementation of closed-loop microelectromechanical system (MEMS) control enables mechanical microsystems to adapt to the demands of the environment that they are actuating, opening a broad range of new opportunities for future MEMS applications. Integrated optical microsystems have the potential to enable continuous in situ optical interrogation of MEMS microstructure position fully decoupled from the means of mechanical actuation that is necessary for realization of feedback control. We present the results of initial research evaluating through-wafer optical microprobes for surface micromachined MEMS integrated optical position monitoring. Results from the through-wafer free-space optical probe of a lateral comb resonator fabricated using the multiuser MEMS process service (MUMPS) indicate significant positional information content with an achievable return probe signal dynamic range of up to 80% arising from film transmission contrast. Static and dynamic deflection analysis and experimental results indicate a through-wafer probe positional signal sensitivity of 40 mV/micrometers for the present setup or 10% signal change per micrometer. A simulation of the application of nonlinear sliding control is presented illustrating position control of the lateral comb resonator structure given the availability of positional state information.

Optical design and testing: introduction.

PubMed

Liang, Chao-Wen; Koshel, John; Sasian, Jose; Breault, Robert; Wang, Yongtian; Fang, Yi Chin

2014-10-10

Optical design and testing has numerous applications in industrial, military, consumer, and medical settings. Assembling a complete imaging or nonimage optical system may require the integration of optics, mechatronics, lighting technology, optimization, ray tracing, aberration analysis, image processing, tolerance compensation, and display rendering. This issue features original research ranging from the optical design of image and nonimage optical stimuli for human perception, optics applications, bio-optics applications, 3D display, solar energy system, opto-mechatronics to novel imaging or nonimage modalities in visible and infrared spectral imaging, modulation transfer function measurement, and innovative interferometry.

Appearance feedback in intimate relationships: the role of self-verification and self-enhancement.

PubMed

Brown, Jennifer N; Stukas, Arthur A; Evans, Lynette

2013-01-01

To better understand how body image operates within the context of intimate relationships, we investigated women's responses to appearance feedback from an intimate partner. Participants (N=192) imagined receiving feedback from their partner that was either consistent with their own appearance self-view (i.e., self-verifying), more positive (i.e., self-enhancing), or less positive (i.e., devaluing), and then provided their affective and cognitive reactions. As expected, women's perceptions of their own appearance moderated their reactions. Women with more negative self-views felt happier with enhancing feedback, but thought that it meant their partner understood them less well. They also felt less happy when they received verifying feedback, but felt more understood by their partners. Thus, women with body image dissatisfaction may find themselves stuck in the "cognitive-affective crossfire" reacting ambivalently whether their partner enhances their appearance or confirms their negative self-views. Further examination of partners' actual feedback is needed. Copyright © 2012 Elsevier Ltd. All rights reserved.

Micro-optical system based 3D imaging for full HD depth image capturing

NASA Astrophysics Data System (ADS)

Park, Yong-Hwa; Cho, Yong-Chul; You, Jang-Woo; Park, Chang-Young; Yoon, Heesun; Lee, Sang-Hun; Kwon, Jong-Oh; Lee, Seung-Wan

2012-03-01

20 Mega-Hertz-switching high speed image shutter device for 3D image capturing and its application to system prototype are presented. For 3D image capturing, the system utilizes Time-of-Flight (TOF) principle by means of 20MHz high-speed micro-optical image modulator, so called 'optical shutter'. The high speed image modulation is obtained using the electro-optic operation of the multi-layer stacked structure having diffractive mirrors and optical resonance cavity which maximizes the magnitude of optical modulation. The optical shutter device is specially designed and fabricated realizing low resistance-capacitance cell structures having small RC-time constant. The optical shutter is positioned in front of a standard high resolution CMOS image sensor and modulates the IR image reflected from the object to capture a depth image. Suggested novel optical shutter device enables capturing of a full HD depth image with depth accuracy of mm-scale, which is the largest depth image resolution among the-state-of-the-arts, which have been limited up to VGA. The 3D camera prototype realizes color/depth concurrent sensing optical architecture to capture 14Mp color and full HD depth images, simultaneously. The resulting high definition color/depth image and its capturing device have crucial impact on 3D business eco-system in IT industry especially as 3D image sensing means in the fields of 3D camera, gesture recognition, user interface, and 3D display. This paper presents MEMS-based optical shutter design, fabrication, characterization, 3D camera system prototype and image test results.

An open source digital servo for atomic, molecular, and optical physics experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leibrandt, D. R., E-mail: david.leibrandt@nist.gov; Heidecker, J.

2015-12-15

We describe a general purpose digital servo optimized for feedback control of lasers in atomic, molecular, and optical physics experiments. The servo is capable of feedback bandwidths up to roughly 1 MHz (limited by the 320 ns total latency); loop filter shapes up to fifth order; multiple-input, multiple-output control; and automatic lock acquisition. The configuration of the servo is controlled via a graphical user interface, which also provides a rudimentary software oscilloscope and tools for measurement of system transfer functions. We illustrate the functionality of the digital servo by describing its use in two example scenarios: frequency control of themore » laser used to probe the narrow clock transition of {sup 27}Al{sup +} in an optical atomic clock, and length control of a cavity used for resonant frequency doubling of a laser.« less

An open source digital servo for atomic, molecular, and optical physics experiments.

PubMed

Leibrandt, D R; Heidecker, J

2015-12-01

We describe a general purpose digital servo optimized for feedback control of lasers in atomic, molecular, and optical physics experiments. The servo is capable of feedback bandwidths up to roughly 1 MHz (limited by the 320 ns total latency); loop filter shapes up to fifth order; multiple-input, multiple-output control; and automatic lock acquisition. The configuration of the servo is controlled via a graphical user interface, which also provides a rudimentary software oscilloscope and tools for measurement of system transfer functions. We illustrate the functionality of the digital servo by describing its use in two example scenarios: frequency control of the laser used to probe the narrow clock transition of (27)Al(+) in an optical atomic clock, and length control of a cavity used for resonant frequency doubling of a laser.

Feedback dew-point sensor utilizing optimally cut plastic optical fibres

NASA Astrophysics Data System (ADS)

Hadjiloucas, S.; Irvine, J.; Keating, D. A.

2000-01-01

A plastic optical fibre reflectance sensor that makes full use of the critical angle of the fibres is implemented to monitor dew formation on a Peltier-cooled reflector surface. The optical configuration permits isolation of optoelectronic components from the sensing head and better light coupling between the reflector and the detecting fibre, giving a better signal of the onset of dew formation on the reflector. Continuous monitoring of the rate of change in reflectance as well as the absolute reflectance signals, the use of a novel polymethyl-methacrylate-coated hydrophobic film reflector on the Peltier element and the application of feedback around the point of dew formation, further reduces the possibility of contamination of the sensor head. Under closed-loop operation, the sensor is capable of cycling around the point of dew formation at a frequency of 2.5 Hz.

An open source digital servo for atomic, molecular, and optical physics experiments

NASA Astrophysics Data System (ADS)

Leibrandt, D. R.; Heidecker, J.

2015-12-01

We describe a general purpose digital servo optimized for feedback control of lasers in atomic, molecular, and optical physics experiments. The servo is capable of feedback bandwidths up to roughly 1 MHz (limited by the 320 ns total latency); loop filter shapes up to fifth order; multiple-input, multiple-output control; and automatic lock acquisition. The configuration of the servo is controlled via a graphical user interface, which also provides a rudimentary software oscilloscope and tools for measurement of system transfer functions. We illustrate the functionality of the digital servo by describing its use in two example scenarios: frequency control of the laser used to probe the narrow clock transition of 27Al+ in an optical atomic clock, and length control of a cavity used for resonant frequency doubling of a laser.

Performance improvement of optical wireless communication through fog with a decision feedback equalizer.

PubMed

Aharonovich, Marius; Arnon, Shlomi

2005-08-01

Optical wireless communication (OWC) systems use the atmosphere as a propagation medium. However, a common problem is that from time to time moderate cloud and fog emerge between the receiver and the transmitter. These adverse weather conditions impose temporal broadening and power loss on the optical signal, which reduces the digital signal-to-noise ratio (DSNR), produces significant intersymbol interference (ISI), and degrades the communication system's bit error rate (BER) and throughput. We propose and investigate the use of a combined adaptive bandwidth mechanism and decision feedback equalizer (DFE) to mitigate these atmospheric multipath effects. Based on theoretical analysis and simulations of DSNR penalties, BER, and optimum system bandwidths, we show that a DFE improves the outdoor OWC system immunity to ISI in foggy weather while maintaining high throughput and desired low BER.

Feedback control of thermal lensing in a high optical power cavity.

PubMed

Fan, Y; Zhao, C; Degallaix, J; Ju, L; Blair, D G; Slagmolen, B J J; Hosken, D J; Brooks, A F; Veitch, P J; Munch, J

2008-10-01

This paper reports automatic compensation of strong thermal lensing in a suspended 80 m optical cavity with sapphire test mass mirrors. Variation of the transmitted beam spot size is used to obtain an error signal to control the heating power applied to the cylindrical surface of an intracavity compensation plate. The negative thermal lens created in the compensation plate compensates the positive thermal lens in the sapphire test mass, which was caused by the absorption of the high intracavity optical power. The results show that feedback control is feasible to compensate the strong thermal lensing expected to occur in advanced laser interferometric gravitational wave detectors. Compensation allows the cavity resonance to be maintained at the fundamental mode, but the long thermal time constant for thermal lensing control in fused silica could cause difficulties with the control of parametric instabilities.

An open source digital servo for atomic, molecular, and optical physics experiments

PubMed Central

Leibrandt, D. R.; Heidecker, J.

2016-01-01

We describe a general purpose digital servo optimized for feedback control of lasers in atomic, molecular, and optical physics experiments. The servo is capable of feedback bandwidths up to roughly 1 MHz (limited by the 320 ns total latency); loop filter shapes up to fifth order; multiple-input, multiple-output control; and automatic lock acquisition. The configuration of the servo is controlled via a graphical user interface, which also provides a rudimentary software oscilloscope and tools for measurement of system transfer functions. We illustrate the functionality of the digital servo by describing its use in two example scenarios: frequency control of the laser used to probe the narrow clock transition of 27Al+ in an optical atomic clock, and length control of a cavity used for resonant frequency doubling of a laser. PMID:26724014

Television-optical operational amplifier.

PubMed

Goetz, J; Häusler, G; Sesselmann, R

1979-08-15

The advantages of negative feedback are well known in electronics and extensively used in the operational amplifier. The properties of such a system are nearly independent of the parameters in the forward branch of the system; they are only determined by external elements in the backward branch. An optical analog of such an operational amplifier is reported. The essential operations, amplifications, and inversion of the circulating signals are carried out using a TV system. The capability of the system to compensate for spatial inhomogeneities and for nonlinearities is demonstrated. In addition, the system is able to create the inverse of a transfer function located in the feedback branch.

Regenerative memory in time-delayed neuromorphic photonic resonators

NASA Astrophysics Data System (ADS)

Romeira, B.; Avó, R.; Figueiredo, José M. L.; Barland, S.; Javaloyes, J.

2016-01-01

We investigate a photonic regenerative memory based upon a neuromorphic oscillator with a delayed self-feedback (autaptic) connection. We disclose the existence of a unique temporal response characteristic of localized structures enabling an ideal support for bits in an optical buffer memory for storage and reshaping of data information. We link our experimental implementation, based upon a nanoscale nonlinear resonant tunneling diode driving a laser, to the paradigm of neuronal activity, the FitzHugh-Nagumo model with delayed feedback. This proof-of-concept photonic regenerative memory might constitute a building block for a new class of neuron-inspired photonic memories that can handle high bit-rate optical signals.

Linear laser diode arrays for improvement in optical disk recording for space stations

NASA Technical Reports Server (NTRS)

Alphonse, G. A.; Carlin, D. B.; Connolly, J. C.

1990-01-01

The design and fabrication of individually addressable laser diode arrays for high performance magneto-optic recording systems are presented. Ten diode arrays with 30 mW cW light output, linear light vs. current characteristics and single longitudinal mode spectrum were fabricated using channel substrate planar (CSP) structures. Preliminary results on the inverse CSP structure, whose fabrication is less critically dependent on device parameters than the CSP, are also presented. The impact of systems parameters and requirements, in particular, the effect of feedback on laser design is assessed, and techniques to reduce feedback or minimize its effect on systems performance, including mode-stabilized structures, are evaluated.

Brain activation upon ideal-body media exposure and peer feedback in late adolescent girls.

PubMed

van der Meulen, Mara; Veldhuis, Jolanda; Braams, Barbara R; Peters, Sabine; Konijn, Elly A; Crone, Eveline A

2017-08-01

Media's prevailing thin-body ideal plays a vital role in adolescent girls' body image development, but the co-occurring impact of peer feedback is understudied. The present study used functional magnetic resonance imaging (fMRI) to test media imagery and peer feedback combinations on neural activity related to thin-body ideals. Twenty-four healthy female late adolescents rated precategorized body sizes of bikini models (too thin or normal), directly followed by ostensible peer feedback (too thin or normal). Consistent with prior studies on social feedback processing, results showed increased brain activity in the dorsal medial prefrontal cortex (dmPFC)/anterior cingulate cortex (ACC) and bilateral insula in incongruent situations: when participants rated media models' body size as normal while peer feedback indicated the models as too thin (or vice versa). This effect was stronger for girls with lower self-esteem. A subsequent behavioral study (N = 34 female late adolescents, separate sample) demonstrated that participants changed behavior in the direction of the peer feedback: precategorized normal sized models were rated as too thin more often after receiving too thin peer feedback. This suggests that the neural responses upon peer feedback may influence subsequent choice. Our results show that media-by-peer interactions have pronounced effects on girls' body ideals.

Evaluating the negative or valuing the positive? Neural mechanisms supporting feedback-based learning across development.

PubMed

van Duijvenvoorde, Anna C K; Zanolie, Kiki; Rombouts, Serge A R B; Raijmakers, Maartje E J; Crone, Eveline A

2008-09-17

How children learn from positive and negative performance feedback lies at the foundation of successful learning and is therefore of great importance for educational practice. In this study, we used functional magnetic resonance imaging (fMRI) to examine the neural developmental changes related to feedback-based learning when performing a rule search and application task. Behavioral results from three age groups (8-9, 11-13, and 18-25 years of age) demonstrated that, compared with adults, 8- to 9-year-old children performed disproportionally more inaccurately after receiving negative feedback relative to positive feedback. Additionally, imaging data pointed toward a qualitative difference in how children and adults use performance feedback. That is, dorsolateral prefrontal cortex and superior parietal cortex were more active after negative feedback for adults, but after positive feedback for children (8-9 years of age). For 11- to 13-year-olds, these regions did not show differential feedback sensitivity, suggesting that the transition occurs around this age. Pre-supplementary motor area/anterior cingulate cortex, in contrast, was more active after negative feedback in both 11- to 13-year-olds and adults, but not 8- to 9-year-olds. Together, the current data show that cognitive control areas are differentially engaged during feedback-based learning across development. Adults engage these regions after signals of response adjustment (i.e., negative feedback). Young children engage these regions after signals of response continuation (i.e., positive feedback). The neural activation patterns found in 11- to 13-year-olds indicate a transition around this age toward an increased influence of negative feedback on performance adjustment. This is the first developmental fMRI study to compare qualitative changes in brain activation during feedback learning across distinct stages of development.

Monitoring and guidance of HIFU beams with dual-mode ultrasound arrays.

PubMed

Ballard, John R; Casper, Andrew J; Ebbini, Emad S

2009-01-01

We present experimental results illustrating the unique advantages of dual-mode array (DMUA) systems in monitoring and guidance of high intensity focused ultrasound (HIFU) lesion formation. DMUAs offer a unique paradigm in image-guided surgery; one in which images obtained using the same therapeutic transducer provide feedback for: 1) refocusing the array in the presence of strongly scattering objects, e.g. the ribs, 2) temperature change at the intended location of the HIFU focus, and 3) changes in the echogenicity of the tissue in response to therapeutic HIFU. These forms of feedback have been demonstrated in vitro in preparation for the design and implementation of a real-time system for imaging and therapy with DMUAs. The results clearly demonstrate that DMUA image feedback is spatially accurate and provide sufficient spatial and contrast resolution for identification of high contrast objects like the ribs and significant blood vessels in the path of the HIFU beam.

The HORUS Observatory - A Next Generation 2.4m UV-Optical Mission To Study Planetary, Stellar And Galactic Formation

NASA Astrophysics Data System (ADS)

Scowen, Paul A.; SDT, HORUS

2013-01-01

The High-ORbit Ultraviolet-visible Satellite (HORUS) is a 2.4-meter class UV-optical space telescope that will conduct a comprehensive and systematic study of the astrophysical processes and environments relevant for the births and life cycles of stars and their planetary systems, to investigate and understand the range of environments, feedback mechanisms, and other factors that most affect the outcome of the star and planet formation process. To do so, HORUS will provide 100 times greater imaging efficiency and more than 10 times greater UV spectroscopic sensitivity than has existed on the Hubble Space Telescope (HST). The HORUS mission will contribute vital information on how solar systems form and whether habitable planets should be common or rare. It also will investigate the structure, evolution, and destiny of galaxies and universe. This program relies on focused capabilities unique to space that no other planned NASA mission will provide: near-UV/visible (200-1075nm) wide-field, diffraction-limited imaging; and high-sensitivity, high-resolution UV (100-170nm) spectroscopy. The core HORUS design will provide wide field of view imagery and high efficiency point source FUV spectroscopy using a novel combination of spectral selection and field sharing. The HORUS Optical Telescope Assembly (OTA) design is based on modern light weight mirror technology with a faster primary mirror to shorten the overall package and thereby reduce mass. The OTA uses a three-mirror anastigmat configuration to provide excellent imagery over a large FOV - and is exactly aligned to use one of the recently released f/1.2 NRO OTAs as part of its design. The UV/optical Imaging Cameras use two 21k x 21k Focal Plane Arrays (FPAs). The FUV spectrometer uses cross strip anode based MCPs. This poster presents results from a 2010 design update requested by the NRC Decadal Survey, and reflects updated costs and technology to the original 2004 study. It is now one of the most mature 2.4m UVOIR observatory designs in NASA’s portfolio.

Near-IR laser frequency standard stabilized using FM-spectroscopy

NASA Astrophysics Data System (ADS)

Ružička, Bohdan; Číp, Ondřej; Lazar, Josef

2006-02-01

At the present time fiber-optics and optical communication are in rapid progress. Modern technologies such as DWDM (Dense Wavelength Division Multiplex) need precise stability of laser frequencies. According to this fact, requirements of new etalons of optical frequencies in the telecommunication band is rapidly growing. Lasers working in near infrared telecommunication band (1500-1600 nm) can be stabilized to 12C IIH II or 13C IIH II (acetylene) gas absorption lines. The acetylene gas absorption has been widely studied and accepted by international bodies of standardization as a primary wavelength reference in the near infrared band around 1550nm. Our aim was to design and develop a compact fibre optics laser system generating coherent light in near-JR band with high frequency stability (at least 1.10 -8). This system should become a base for realization of a primary frequency standard for optical communications in the Czech Republic. Such an etalon will be needed for calibration of wavelength-meters and spectral analysers for DWDM communication systems. We are co-operating with CMI (Czech Metrology Institute) on this project. We present stabilized laser system based on a single frequency DFB (Distributed Feedback) laser diode with a narrow spectral profile. The laser is pre-stabilized by means of the FM-spectroscopy on a passive resonator. Thanks to a fast feed-back loop we are able to improve spectral characteristics of the laser. The laser frequency is locked by a relatively slow second feed-back loop on an absorption line of acetylene vapour which is sealed in a cell under the optimised pressure.

Cortical feedback signals generalise across different spatial frequencies of feedforward inputs.

PubMed

Revina, Yulia; Petro, Lucy S; Muckli, Lars

2017-09-22

Visual processing in cortex relies on feedback projections contextualising feedforward information flow. Primary visual cortex (V1) has small receptive fields and processes feedforward information at a fine-grained spatial scale, whereas higher visual areas have larger, spatially invariant receptive fields. Therefore, feedback could provide coarse information about the global scene structure or alternatively recover fine-grained structure by targeting small receptive fields in V1. We tested if feedback signals generalise across different spatial frequencies of feedforward inputs, or if they are tuned to the spatial scale of the visual scene. Using a partial occlusion paradigm, functional magnetic resonance imaging (fMRI) and multivoxel pattern analysis (MVPA) we investigated whether feedback to V1 contains coarse or fine-grained information by manipulating the spatial frequency of the scene surround outside an occluded image portion. We show that feedback transmits both coarse and fine-grained information as it carries information about both low (LSF) and high spatial frequencies (HSF). Further, feedback signals containing LSF information are similar to feedback signals containing HSF information, even without a large overlap in spatial frequency bands of the HSF and LSF scenes. Lastly, we found that feedback carries similar information about the spatial frequency band across different scenes. We conclude that cortical feedback signals contain information which generalises across different spatial frequencies of feedforward inputs. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

An integral design strategy combining optical system and image processing to obtain high resolution images

NASA Astrophysics Data System (ADS)

Wang, Jiaoyang; Wang, Lin; Yang, Ying; Gong, Rui; Shao, Xiaopeng; Liang, Chao; Xu, Jun

2016-05-01

In this paper, an integral design that combines optical system with image processing is introduced to obtain high resolution images, and the performance is evaluated and demonstrated. Traditional imaging methods often separate the two technical procedures of optical system design and imaging processing, resulting in the failures in efficient cooperation between the optical and digital elements. Therefore, an innovative approach is presented to combine the merit function during optical design together with the constraint conditions of image processing algorithms. Specifically, an optical imaging system with low resolution is designed to collect the image signals which are indispensable for imaging processing, while the ultimate goal is to obtain high resolution images from the final system. In order to optimize the global performance, the optimization function of ZEMAX software is utilized and the number of optimization cycles is controlled. Then Wiener filter algorithm is adopted to process the image simulation and mean squared error (MSE) is taken as evaluation criterion. The results show that, although the optical figures of merit for the optical imaging systems is not the best, it can provide image signals that are more suitable for image processing. In conclusion. The integral design of optical system and image processing can search out the overall optimal solution which is missed by the traditional design methods. Especially, when designing some complex optical system, this integral design strategy has obvious advantages to simplify structure and reduce cost, as well as to gain high resolution images simultaneously, which has a promising perspective of industrial application.

Active galactic nucleus and quasar science with aperture masking interferometry on the James Webb Space Telescope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ford, K. E. Saavik; McKernan, Barry; Sivaramakrishnan, Anand

Due to feedback from accretion onto supermassive black holes (SMBHs), active galactic nuclei (AGNs) are believed to play a key role in ΛCDM cosmology and galaxy formation. However, AGNs extreme luminosities and the small angular size of their accretion flows create a challenging imaging problem. We show that the James Webb Space Telescope's Near Infrared Imager and Slitless Spectrograph (JWST-NIRISS) Aperture Masking Interferometry (AMI) mode will enable true imaging (i.e., without any requirement of prior assumptions on source geometry) at ∼65 mas angular resolution at the centers of AGNs. This is advantageous for studying complex extended accretion flows around SMBHsmore » and in other areas of angular-resolution-limited astrophysics. By simulating data sequences incorporating expected sources of noise, we demonstrate that JWST-NIRISS AMI mode can map extended structure at a pixel-to-pixel contrast of ∼10{sup –2} around an L = 7.5 point source, using short exposure times (minutes). Such images will test models of AGN feedback, fueling, and structure (complementary with ALMA observations), and are not currently supported by any ground-based IR interferometer or telescope. Binary point source contrast with NIRISS is ∼10{sup –4} (for observing binary nuclei in merging galaxies), significantly better than current ground-based optical or IR interferometry. JWST-NIRISS's seven-hole non-redundant mask has a throughput of 15%, and utilizes NIRISS's F277W (2.77 μm), F380M (3.8 μm), F430M (4.3 μm), and F480M (4.8 μm) filters. NIRISS's square pixels are 65 mas per side, with a field of view ∼2' × 2'. We also extrapolate our results to AGN science enabled by non-redundant masking on future 2.4 m and 16 m space telescopes working at long-UV to near-IR wavelengths.« less

Automated numerical simulation of biological pattern formation based on visual feedback simulation framework

PubMed Central

Sun, Mingzhu; Xu, Hui; Zeng, Xingjuan; Zhao, Xin

2017-01-01

There are various fantastic biological phenomena in biological pattern formation. Mathematical modeling using reaction-diffusion partial differential equation systems is employed to study the mechanism of pattern formation. However, model parameter selection is both difficult and time consuming. In this paper, a visual feedback simulation framework is proposed to calculate the parameters of a mathematical model automatically based on the basic principle of feedback control. In the simulation framework, the simulation results are visualized, and the image features are extracted as the system feedback. Then, the unknown model parameters are obtained by comparing the image features of the simulation image and the target biological pattern. Considering two typical applications, the visual feedback simulation framework is applied to fulfill pattern formation simulations for vascular mesenchymal cells and lung development. In the simulation framework, the spot, stripe, labyrinthine patterns of vascular mesenchymal cells, the normal branching pattern and the branching pattern lacking side branching for lung branching are obtained in a finite number of iterations. The simulation results indicate that it is easy to achieve the simulation targets, especially when the simulation patterns are sensitive to the model parameters. Moreover, this simulation framework can expand to other types of biological pattern formation. PMID:28225811

Automated numerical simulation of biological pattern formation based on visual feedback simulation framework.

PubMed

Sun, Mingzhu; Xu, Hui; Zeng, Xingjuan; Zhao, Xin

2017-01-01

There are various fantastic biological phenomena in biological pattern formation. Mathematical modeling using reaction-diffusion partial differential equation systems is employed to study the mechanism of pattern formation. However, model parameter selection is both difficult and time consuming. In this paper, a visual feedback simulation framework is proposed to calculate the parameters of a mathematical model automatically based on the basic principle of feedback control. In the simulation framework, the simulation results are visualized, and the image features are extracted as the system feedback. Then, the unknown model parameters are obtained by comparing the image features of the simulation image and the target biological pattern. Considering two typical applications, the visual feedback simulation framework is applied to fulfill pattern formation simulations for vascular mesenchymal cells and lung development. In the simulation framework, the spot, stripe, labyrinthine patterns of vascular mesenchymal cells, the normal branching pattern and the branching pattern lacking side branching for lung branching are obtained in a finite number of iterations. The simulation results indicate that it is easy to achieve the simulation targets, especially when the simulation patterns are sensitive to the model parameters. Moreover, this simulation framework can expand to other types of biological pattern formation.

Self-Mixing Thin-Slice Solid-State Laser Metrology

PubMed Central

Otsuka, Kenju

2011-01-01

This paper reviews the dynamic effect of thin-slice solid-state lasers subjected to frequency-shifted optical feedback, which led to the discovery of the self-mixing modulation effect, and its applications to quantum-noise-limited versatile laser metrology systems with extreme optical sensitivity. PMID:22319406

Small jets in radio-loud hot DOGs

NASA Astrophysics Data System (ADS)

Lonsdale, C. J.; Whittle, M.; Trapp, A.; Patil, P.; Lonsdale, C. J.; Thorp, R.; Lacy, M.; Kimball, A. E.; Blain, A.; Jones, S.; Kim, M.

2016-02-01

We address the impact of young radio jets on the ISM and star formation in a sample of radiatively efficient, highly obscured, radio AGN with look back times that place them near the peak of the galaxy and BH building era, z˜ 1-3. By selecting systems with a high mid-infrared (MIR) luminosity we aim to identify radiatively efficient (``quasar-mode'' or ``radiative-mode") AGN in a peak fueling phase, and by selecting compact radio sources we favor young or re-generated radio jets which are confined within the hosts. By selecting AGN which are very red through the optical-MIR we favor highly obscured systems likely to have been recently merger-triggered and still in the pre-blow-out phase of AGN feedback into the surrounding ISM. ALMA imaging at 345 GHz of 49 sources has revealed that they are accretion dominated, relative to star formation, with luminosities reaching 1014 L⊙. Extensive VLA imaging at 8-10 GHz in both A-array and B-array for 155 sources reveals that the majority of these powerful radio systems are compact on < 2-5 kpc scales while some have resolved structures on 3-25 kpc scales, and a small number have giant radio lobes on hundreds of kpc scales. The majority of the GHz range radio SEDs are typical of optically thin synchrotron, however for the 34 sources with data at more than 2 frequencies, 40 % are likely to be CSS, GPS, or HFP sources. VLBA imaging of 62 sources reveals varied morphologies, from unresolved sources to complex multicomponent 1-10 mas scale structures. Data from ALMA, VLA, and VLBA

Improving the performance of interferometric imaging through the use of disturbance feedforward.

PubMed

Böhm, Michael; Glück, Martin; Keck, Alexander; Pott, Jörg-Uwe; Sawodny, Oliver

2017-05-01

In this paper, we present a disturbance compensation technique to improve the performance of interferometric imaging for extremely large ground-based telescopes, e.g., the Large Binocular Telescope (LBT), which serves as the application example in this contribution. The most significant disturbance sources at ground-based telescopes are wind-induced mechanical vibrations in the range of 8-60 Hz. Traditionally, their optical effect is eliminated by feedback systems, such as the adaptive optics control loop combined with a fringe tracking system within the interferometric instrument. In this paper, accelerometers are used to measure the vibrations. These measurements are used to estimate the motion of the mirrors, i.e., tip, tilt and piston, with a dynamic estimator. Additional delay compensation methods are presented to cancel sensor network delays and actuator input delays, improving the estimation result even more, particularly at higher frequencies. Because various instruments benefit from the implementation of telescope vibration mitigation, the estimator is implemented as a separate, independent software on the telescope, publishing the estimated values via multicast on the telescope's ethernet. Every client capable of using and correcting the estimated disturbances can subscribe and use these values in a feedforward for its compensation device, e.g., the deformable mirror, the piston mirror of LINC-NIRVANA, or the fast path length corrector of the Large Binocular Telescope Interferometer. This easy-to-use approach eventually leveraged the presented technology for interferometric use at the LBT and now significantly improves the sky coverage, performance, and operational robustness of interferometric imaging on a regular basis.

Fabrication of miniature elastomer lenses with programmable liquid mold for smartphone microscopy: curing polydimethylsiloxane with in situ curvature control.

PubMed

Karunakaran, Bhuvaneshwari; Tharion, Joseph; Dhawangale, Arvind Ramrao; Paul, Debjani; Mukherji, Soumyo

2018-02-01

Miniature lenses can transform commercial imaging systems, e.g., smartphones and webcams, into powerful, low-cost, handheld microscopes. To date, the reproducible fabrication of polymer lenses is still a challenge as they require controlled dispensing of viscous liquid. This paper reports a reproducible lens fabrication technique using liquid mold with programmable curvature and off-the-shelf materials. The lens curvature is controlled during fabrication by tuning the curvature of an interface of two immiscible liquids [polydimethylsiloxane (PDMS) and glycerol]. The curvature control is implemented using a visual feedback system, which includes a software-based guiding system to produce lenses of desired curvature. The technique allows PDMS lens fabrication of a wide range of sizes and focal lengths, within 20 min. The fabrication of two lens diameters: 1 and 5 mm with focal lengths ranging between 1.2 and 11 mm are demonstrated. The lens surface and bulk quality check performed using X-ray microtomography and atomic force microscopy reveal that the lenses are suitable for optical imaging. Furthermore, a smartphone microscope with ∼1.4-μm resolution is developed using a self-assembly of a single high power fabricated lens and microaperture. The lenses have various potential applications, e.g., optofluidics, diagnostics, forensics, and surveillance. (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

Looking for Galaxies in All the Right Places: A Search for Stellar Populations in ALFALFA’s Ultra-compact High Velocity Clouds

NASA Astrophysics Data System (ADS)

Janesh, William; Rhode, Katherine L.; Salzer, John J.; Janowiecki, Steven; Adams, Elizabeth; Haynes, Martha P.; Giovanelli, Riccardo; Cannon, John M.

2018-01-01

Nearby gas-rich dwarf galaxies are excellent laboratories for investigating the baryonic feedback processes that govern star formation and galaxy evolution in galaxies at the extreme end of the mass function. Detecting and studying such objects may help resolve the well-known tension between cosmological model predictions for low-mass dark matter halos and observations. The ALFALFA neutral hydrogen (Hi) survey has detected a sample of isolated ultra-compact high-velocity Hi clouds (UCHVCs) with kinematic properties that make them likely members of the Local Volume, but that have no optical counterparts in existing optical surveys. This UCHVC sample possesses Hi properties (at 1 Mpc, Hi masses of ~105-106 M⊙, Hi diameters of ~2-3 kpc, and dynamical masses of ~107-108 M⊙) similar to other known ultra-faint dwarf galaxies like Leo T. Following the discovery of Leo P, an extremely metal-poor, gas-rich star-forming dwarf galaxy associated with an ALFALFA UCHVC, we have initiated a campaign to obtain deep optical imaging of 56 UCHVCs using the wide field-of-view, high-resolution ODI camera on the WIYN 3.5-m telescope. Here we present a brief overview of our campaign to search for resolved stellar populations associated with the UCHVCs in our optical images, and initial results from our survey.After creating a stellar catalog from the pipeline-reduced and stacked ODI g- and i-band images, we apply a color-magnitude filter tuned for old, metal-poor stellar populations to select red giant branch stars at distances between 250 kpc and 2 Mpc. The spatial distribution of the stars selected by the filter is then smoothed, and overdensities in the fields are identified. Of the 22 targets analyzed to date, seven have associated stellar populations detected at a high confidence (92% to 99.9% significance). The detected objects have a range of distances (from 350 kpc to 1.6 Mpc) and have optical properties similar to those of ultra-faint dwarf galaxies. These objects have extreme Hi-to-stellar mass ratios, and given their isolation, may represent a progenitor population to the ultra-faint dwarfs. They also help constrain the conditions needed for star formation in the lowest-mass galaxies.

Fabrication and application of heterogeneous printed mouse phantoms for whole animal optical imaging

PubMed Central

Bentz, Brian Z.; Chavan, Anmol V.; Lin, Dergan; Tsai, Esther H. R.; Webb, Kevin J.

2017-01-01

This work demonstrates the usefulness of 3D printing for optical imaging applications. Progress in developing optical imaging for biomedical applications requires customizable and often complex objects for testing and evaluation. There is therefore high demand for what have become known as tissue-simulating “phantoms.” We present a new optical phantom fabricated using inexpensive 3D printing methods with multiple materials, allowing for the placement of complex inhomogeneities in complex or anatomically realistic geometries, as opposed to previous phantoms, which were limited to simple shapes formed by molds or machining. We use diffuse optical imaging to reconstruct optical parameters in 3D space within a printed mouse to show the applicability of the phantoms for developing whole animal optical imaging methods. This phantom fabrication approach is versatile, can be applied to optical imaging methods besides diffusive imaging, and can be used in the calibration of live animal imaging data. PMID:26835763

Hybrid optical and electronic laser locking using slow light due to spectral holes

NASA Astrophysics Data System (ADS)

Tay, Jian Wei; Farr, Warrick G.; Ledingham, Patrick M.; Korystov, Dmitry; Longdell, Jevon J.

2013-06-01

We report on a narrow linewidth laser diode system that is stabilized using both optical and electronic feedback to a spectral hole in cryogenic Tm:YAG. The large group delay of the spectral hole leads to a laser with very low phase noise. The laser has proved useful for quantum optics and sensing applications involving cryogenic rare-earth-ion dopants.

Do They Hear You?

ERIC Educational Resources Information Center

Hattie, John; Fisher, Douglas; Frey, Nancy

2016-01-01

Although research indicates that feedback can be one of the most effective instructional strategies for improving student performance, getting students to listen and act on feedback can be complicated. If feedback is vague and personal, students may pay attention only to positive comments that are positive and boost their self-image ("That…

Feedback traps for virtual potentials

NASA Astrophysics Data System (ADS)

Gavrilov, Momčilo; Bechhoefer, John

2017-03-01

Feedback traps are tools for trapping and manipulating single charged objects, such as molecules in solution. An alternative to optical tweezers and other single-molecule techniques, they use feedback to counteract the Brownian motion of a molecule of interest. The trap first acquires information about a molecule's position and then applies an electric feedback force to move the molecule. Since electric forces are stronger than optical forces at small scales, feedback traps are the best way to trap single molecules without `touching' them (e.g. by putting them in a small box or attaching them to a tether). Feedback traps can do more than trap molecules: they can also subject a target object to forces that are calculated to be the gradient of a desired potential function U(x). If the feedback loop is fast enough, it creates a virtual potential whose dynamics will be very close to those of a particle in an actual potential U(x). But because the dynamics are entirely a result of the feedback loop-absent the feedback, there is only an object diffusing in a fluid-we are free to specify and then manipulate in time an arbitrary potential U(x,t). Here, we review recent applications of feedback traps to studies on the fundamental connections between information and thermodynamics, a topic where feedback plays an even more fundamental role. We discuss how recursive maximum-likelihood techniques allow continuous calibration, to compensate for drifts in experiments that last for days. We consider ways to estimate work and heat, using them to measure fluctuating energies to a precision of ±0.03 kT over these long experiments. Finally, we compare work and heat measurements of the costs of information erasure, the Landauer limit of kT ln 2 per bit of information erased. We argue that, when you want to know the average heat transferred to a bath in a long protocol, you should measure instead the average work and then infer the heat using the first law of thermodynamics. This article is part of the themed issue 'Horizons of cybernetical physics'.

Optical integrator for optical dark-soliton detection and pulse shaping.

PubMed

Ngo, Nam Quoc

2006-09-10

The design and analysis of an Nth-order optical integrator using the digital filter technique is presented. The optical integrator is synthesized using planar-waveguide technology. It is shown that a first-order optical integrator can be used as an optical dark-soliton detector by converting an optical dark-soliton pulse into an optical bell-shaped pulse for ease of detection. The optical integrators can generate an optical step function, staircase function, and paraboliclike functions from input optical Gaussian pulses. The optical integrators may be potentially used as basic building blocks of all-optical signal processing systems because the time integrals of signals may sometimes be required for further use or analysis. Furthermore, an optical integrator may be used for the shaping of optical pulses or in an optical feedback control system.

Constraining Aggregate-Scale Solar Energy Partitioning in Arctic Sea Ice Through Synthesis of Remote Sensing and Autonomous In-Situ Observations.

NASA Astrophysics Data System (ADS)

Wright, N.; Polashenski, C. M.; Deeb, E. J.; Morriss, B. F.; Song, A.; Chen, J.

2015-12-01

One of the key processes controlling sea ice mass balance in the Arctic is the partitioning of solar energy between reflection back to the atmosphere and absorption into the ice and upper ocean. We investigate the solar energy balance in the ice-ocean system using in-situ data collected from Arctic Observing Network (AON) sea ice sites and imagery from high resolution optical satellites. AON assets, including ice mass balance buoys and ice tethered profilers, monitor the storage and fluxes of heat in the ice-ocean system. High resolution satellite imagery, processed using object-based image classification techniques, allows us to quantify the evolution of surrounding ice conditions, including melt pond coverage and floe size distribution, at aggregate scale. We present results from regionally representative sites that constrain the partitioning of absorbed solar energy between ice melt and ocean storage, and quantify the strength of the ice-albedo feedback. We further demonstrate how the results can be used to validate model representations of the physical processes controlling ice-albedo feedbacks. The techniques can be extended to understand solar partitioning across the Arctic basin using additional sites and model based data integration.

Watching AGN feedback at its birth: HST observations of nascent outflow host IC860

NASA Astrophysics Data System (ADS)

Alatalo, Katherine

2016-10-01

IC860 is a nearby IR-luminous early-type spiral with a unique set of properties: it is a shocked, poststarburst galaxy that hosts an AGN-driven neutral wind and a compact core of molecular gas. IC860 can serve as a rosetta stone for the early stages of triggering AGN feedback. We propose to use WFC3 on HST to obtain NUV, optical and near-IR imaging of IC860. We will create a spatially-resolved history of star formation quenching through SED-fitting of 7 requested broadband filters, and compare the spatially resolved star formation histories to in different positions within the underlying stellar features (such as spiral structure) that might define a narrative of how star formation is quenching in IC860. These observations will also resolve the super-star cluster sites to trace the most recent star formation. Finally, these observations will trace the mass of the outflow by building an absorption map of the dust. IC860 presents a unique opportunity to study a galaxy at an early stage of transitioning from blue spiral to red early-type galaxy, that also hosts an AGN-driven neutral wind and a compact, turbulent molecular gas core.

Scanned Image Projection System Employing Intermediate Image Plane

NASA Technical Reports Server (NTRS)

DeJong, Christian Dean (Inventor); Hudman, Joshua M. (Inventor)

2014-01-01

In imaging system, a spatial light modulator is configured to produce images by scanning a plurality light beams. A first optical element is configured to cause the plurality of light beams to converge along an optical path defined between the first optical element and the spatial light modulator. A second optical element is disposed between the spatial light modulator and a waveguide. The first optical element and the spatial light modulator are arranged such that an image plane is created between the spatial light modulator and the second optical element. The second optical element is configured to collect the diverging light from the image plane and collimate it. The second optical element then delivers the collimated light to a pupil at an input of the waveguide.

Programmable Iterative Optical Image And Data Processing

NASA Technical Reports Server (NTRS)

Jackson, Deborah J.

1995-01-01

Proposed method of iterative optical image and data processing overcomes limitations imposed by loss of optical power after repeated passes through many optical elements - especially, beam splitters. Involves selective, timed combination of optical wavefront phase conjugation and amplification to regenerate images in real time to compensate for losses in optical iteration loops; timing such that amplification turned on to regenerate desired image, then turned off so as not to regenerate other, undesired images or spurious light propagating through loops from unwanted reflections.

Optical Detection of Ultrasound in Photoacoustic Imaging

PubMed Central

Dong, Biqin; Sun, Cheng; Zhang, Hao F.

2017-01-01

Objective Photoacoustic (PA) imaging emerges as a unique tool to study biological samples based on optical absorption contrast. In PA imaging, piezoelectric transducers are commonly used to detect laser-induced ultrasonic waves. However, they typically lack adequate broadband sensitivity at ultrasonic frequency higher than 100 MHz while their bulky size and optically opaque nature cause technical difficulties in integrating PA imaging with conventional optical imaging modalities. To overcome these limitations, optical methods of ultrasound detection were developed and shown their unique applications in photoacoustic imaging. Methods We provide an overview of recent technological advances in optical methods of ultrasound detection and their applications in PA imaging. A general theoretical framework describing sensitivity, bandwidth, and angular responses of optical ultrasound detection is also introduced. Results Optical methods of ultrasound detection can provide improved detection angle and sensitivity over significantly extended bandwidth. In addition, its versatile variants also offer additional advantages, such as device miniaturization, optical transparency, mechanical flexibility, minimal electrical/mechanical crosstalk, and potential noncontact PA imaging. Conclusion The optical ultrasound detection methods discussed in this review and their future evolution may play an important role in photoacoustic imaging for biomedical study and clinical diagnosis. PMID:27608445

Time delay signature elimination of chaos in a semiconductor laser by dispersive feedback from a chirped FBG.

PubMed

Wang, Daming; Wang, Longsheng; Zhao, Tong; Gao, Hua; Wang, Yuncai; Chen, Xianfeng; Wang, Anbang

2017-05-15

Time delay signature (TDS) of a semiconductor laser subject to dispersive optical feedback from a chirped fibre Bragg grating (CFBG) is investigated experimentally and numerically. Different from mirror, CFBG provides additional frequency-dependent delay caused by dispersion, and thus induces external-cavity modes with irregular mode separation rather than a fixed separation induced by mirror feedback. Compared with mirror feedback, the CFBG feedback can greatly depress and even eliminate the TDS, although it leads to a similar quasi-period route to chaos with increases of feedback. In experiments, by using a CFBG with dispersion of 2000ps/nm, the TDS is decreased by 90% to about 0.04 compared with mirror feedback. Furthermore, both numerical and experimental results show that the TDS evolution is quite different: the TDS decreases more quickly down to a lower plateau (even background noise level of autocorrelation function) and never rises again. This evolution tendency is also different from that of FBG feedback, of which the TDS first decreases to a minimal value and then increases again as feedback strength increases. In addition, the CFBG feedback has no filtering effects and does not require amplification for feedback light.

Three-Dimensional Self-Organization in Nanocomposite Layered Systems by Ultrafast Laser Pulses.

PubMed

Liu, Zeming; Siegel, Jan; Garcia-Lechuga, Mario; Epicier, Thierry; Lefkir, Yaya; Reynaud, Stéphanie; Bugnet, Matthieu; Vocanson, Francis; Solis, Javier; Vitrant, Guy; Destouches, Nathalie

2017-05-23

Controlling plasmonic systems with nanometer resolution in transparent films and their colors over large nonplanar areas is a key issue for spreading their use in various industrial fields. Using light to direct self-organization mechanisms provides high-speed and flexible processes to meet this challenge. Here, we describe a route for the laser-induced self-organization of metallic nanostructures in 3D. Going beyond the production of planar nanopatterns, we demonstrate that ultrafast laser-induced excitation combined with nonlinear feedback mechanisms in a nanocomposite thin film can lead to 3D self-organized nanostructured films. The process, which can be extended to complex layered composite systems, produces highly uniform large-area nanopatterns. We show that 3D self-organization originates from the simultaneous excitation of independent optical modes at different depths in the film and is activated by the plasmon-induced charge separation and thermally induced NP growth mechanisms. This laser color marking technique enables multiplexed optical image encoding and the generated nanostructured Ag NPs:TiO 2 films offer great promise for applications in solar energy harvesting, photocatalysis, or photochromic devices.

Dichroic beamsplitter for high energy laser diagnostics

DOEpatents

LaFortune, Kai N [Livermore, CA; Hurd, Randall [Tracy, CA; Fochs, Scott N [Livermore, CA; Rotter, Mark D [San Ramon, CA; Hackel, Lloyd [Livermore, CA

2011-08-30

Wavefront control techniques are provided for the alignment and performance optimization of optical devices. A Shack-Hartmann wavefront sensor can be used to measure the wavefront distortion and a control system generates feedback error signal to optics inside the device to correct the wavefront. The system can be calibrated with a low-average-power probe laser. An optical element is provided to couple the optical device to a diagnostic/control package in a way that optimizes both the output power of the optical device and the coupling of the probe light into the diagnostics.

OPTICS (Operational Threat Integrated Corrective Spectacles) Production and Initial Human Factors Testing (Lunettes Optics (Lunettes Correctrices Integrees a L’equipment de protection Contre les Menaces Operationnelles) - Production et Essais Initiaux Relatifs Aux Facteurs Humains)

DTIC Science & Technology

2006-06-01

Integrated Corrective Spectacles (OPTICS) concepts . The aim of the OPTICS project is to develop an integrated set of corrective eyewear inserts that...months, three different OPTICS concepts were designed, developed and delivered to DCIEM. An iterative design approach with user feedback was utilized...Each concept employed a different approach for meeting the aims of the device; Concept 0 utilized a Commercial Off the Shelf sports-style

Tomographical process monitoring of laser transmission welding with OCT

NASA Astrophysics Data System (ADS)

Ackermann, Philippe; Schmitt, Robert

2017-06-01

Process control of laser processes still encounters many obstacles. Although these processes are stable, a narrow process parameter window during the process or process deviations have led to an increase on the requirements for the process itself and on monitoring devices. Laser transmission welding as a contactless and locally limited joining technique is well-established in a variety of demanding production areas. For example, sensitive parts demand a particle-free joining technique which does not affect the inner components. Inline integrated non-destructive optical measurement systems capable of providing non-invasive tomographical images of the transparent material, the weld seam and its surrounding areas with micron resolution would improve the overall process. Obtained measurement data enable qualitative feedback into the system to adapt parameters for a more robust process. Within this paper we present the inline monitoring device based on Fourier-domain optical coherence tomography developed within the European-funded research project "Manunet Weldable". This device, after adaptation to the laser transmission welding process is optically and mechanically integrated into the existing laser system. The main target lies within the inline process control destined to extract tomographical geometrical measurement data from the weld seam forming process. Usage of this technology makes offline destructive testing of produced parts obsolete. 1,2,3,4

[INVITED] Surface plasmon cavities on optical fiber end-facets for biomolecule and ultrasound detection

NASA Astrophysics Data System (ADS)

Yang, Tian; He, Xiaolong; Zhou, Xin; Lei, Zeyu; Wang, Yalin; Yang, Jie; Cai, De; Chen, Sung-Liang; Wang, Xueding

2018-05-01

Integrating surface plasmon resonance (SPR) devices upon single-mode fiber (SMF) end facets renders label-free sensing systems that have a simple dip-and-read configuration, a small form factor, high compatibility with fiber-optic techniques, and invasive testing capability. Such devices are not only low cost replacement of current equipments in centralized laboratories, but also highly desirable for opening paths to new applications of label-free optical sensing technologies, such as point-of-care immunological tests and intravascular ultrasound imaging. In this paper, we explain the requirements and challenges for such devices from the perspectives of biomolecule and ultrasound detection applications. In such a context, we review our recent work on SMF end-facet SPR cavities. This include a glue-and-strip fabrication method to transfer a nano-patterned thin gold film to the SMF end-facet with high yield, high quality and high alignment precision, the designs of distributed Bragg reflector (DBR) and distributed feedback (DFB) SPR cavities that couple efficiently with the SMF guided mode and reach quality factors of over 100, and the preliminary results for biomolecule interaction sensing and ultrasound detection. The particular advantages and potential values of these devices have been discussed, in terms of sensitivity, data reliability, reproducibility, bandwidth, etc.

Adaptive control of interface by temperature and interface profile feedback in transparent multi-zone crystal growth furnace

NASA Technical Reports Server (NTRS)

Batur, Celal

1991-01-01

The objective of this research is to control the dynamics of multizone programmable crystal growth furnaces. Due to the inevitable heat exchange among different heating zones and the transient nature of the process, the dynamics of multizone furnaces is time varying, distributed, and therefore complex in nature. Electrical power to heating zones and the translational speed of the ampoule are employed as inputs to control the dynamics. Structural properties of the crystal is the ultimate aim of this adaptive control system. These properties can be monitored in different ways. Following an order of complexity, these may include: (1) on line measurement of the material optical properties such as the refractive index of crystal; (2) on line x-ray imaging of the interface topology; (3) on line optical quantification of the interface profile such as the determination of concavity or convexity of the interface shape; and (4) on line temperature measurement at points closest to the material such as measurements of the ampoule's outside and inside surface temperatures. The research performed makes use of the temperature and optical measurements, specified in (3) and (4) as the outputs of furnace dynamics. However, if the instrumentation is available, the proposed control methodology can be extended to the measurements listed in (1) and (2).

Arcus: An Overview of the Soft X-ray Grating Explorer

NASA Astrophysics Data System (ADS)

Smith, Randall; Arcus Collaboration

2018-01-01

The Arcus MIDEX Explorer, which NASA selected for a Phase A study in August 2017, provides high-resolution soft X-ray spectroscopy in the 12-50Å bandpass with unprecedented sensitivity. Its capabilities include spectral resolution >2500 and effective areas in the range 200-600 cm^2. The three top science goals for Arcus are (1) to measure the effects of structure formation imprinted upon the hot baryons that are predicted to lie in extended halos around galaxies, groups, and clusters, (2) to trace the propagation of outflowing mass, energy, and momentum from the vicinity of the black hole to extragalactic scales as a measure of their feedback and (3) to explore how stars, circumstellar disks and exoplanet atmospheres form and evolve. Arcus relies upon the same 12m focal length grazing-incidence silicon pore X-ray optics (SPO) that ESA has developed for the Athena mission; the focal length is achieved on orbit via an extendable optical bench. The focused X-rays from these optics are diffracted by high-efficiency Critical-Angle Transmission (CAT) gratings, and the results are imaged with flight-proven CCD detectors and electronics. The power and telemetry requirements on the spacecraft are modest and mission operations are straightforward, as most observations will be long (~100 ksec), uninterrupted, and pre-planned.

Instrumentation in Diffuse Optical Imaging

PubMed Central

Zhang, Xiaofeng

2014-01-01

Diffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence, and a number of other new imaging methods. These methods of diffuse optical imaging have diversified instrument configurations but share the same core physical principle – light propagation in highly diffusive media, i.e., the biological tissue. In this review, the author summarizes the latest development in instrumentation and methodology available to diffuse optical imaging in terms of system architecture, light source, photo-detection, spectral separation, signal modulation, and lastly imaging contrast. PMID:24860804

Formation Control of the MAXIM L2 Libration Orbit Mission

NASA Technical Reports Server (NTRS)

Folta, David; Hartman, Kate; Howell, Kathleen; Marchand, Belinda

2004-01-01

The Micro-Arcsecond Imaging Mission (MAXIM), a proposed concept for the Structure and Evolution of the Universe (SEU) Black Hole Imaging mission, is designed to make a ten million-fold improvement in X-ray image clarity of celestial objects by providing better than 0.1 microarcsecond imaging. To achieve mission requirements, MAXIM will have to improve on pointing by orders of magnitude. This pointing requirement impacts the control and design of the formation. Currently the architecture is comprised of 25 spacecraft, which will form the sparse apertures of a grazing incidence X-ray interferometer covering the 0.3-10 keV bandpass. This configuration will deploy 24 spacecraft as optics modules and one as the detector. The formation must allow for long duration continuous science observations and also for reconfiguration that permits re-pointing of the formation. In this paper, we provide analysis and trades of several control efforts that are dependent upon the pointing requirements and the configuration and dimensions of the MAXIM formation. We emphasize the utilization of natural motions in the Lagrangian regions that minimize the control efforts and we address both continuous and discrete control via LQR and feedback linearization. Results provide control cost, configuration options, and capabilities as guidelines for the development of this complex mission.

Imaging and applied optics: introduction to the feature issue.

PubMed

Zalevsky, Zeev; Arnison, Matthew R; Javidi, Bahram; Testorf, Markus

2018-03-01

This special issue of Applied Optics contains selected papers from OSA's Imaging Congress with particular emphasis on work from mathematics in imaging, computational optical sensing and imaging, imaging systems and applications, and 3D image acquisition and display.

Fibre-optic nonlinear optical microscopy and endoscopy.

PubMed

Fu, L; Gu, M

2007-06-01

Nonlinear optical microscopy has been an indispensable laboratory tool of high-resolution imaging in thick tissue and live animals. Rapid developments of fibre-optic components in terms of growing functionality and decreasing size provide enormous opportunities for innovations in nonlinear optical microscopy. Fibre-based nonlinear optical endoscopy is the sole instrumentation to permit the cellular imaging within hollow tissue tracts or solid organs that are inaccessible to a conventional optical microscope. This article reviews the current development of fibre-optic nonlinear optical microscopy and endoscopy, which includes crucial technologies for miniaturized nonlinear optical microscopy and their embodiments of endoscopic systems. A particular attention is given to several classes of photonic crystal fibres that have been applied to nonlinear optical microscopy due to their unique properties for ultrashort pulse delivery and signal collection. Furthermore, fibre-optic nonlinear optical imaging systems can be classified into portable microscopes suitable for imaging behaving animals, rigid endoscopes that allow for deep tissue imaging with minimally invasive manners, and flexible endoscopes enabling imaging of internal organs. Fibre-optic nonlinear optical endoscopy is coming of age and a paradigm shift leading to optical microscope tools for early cancer detection and minimally invasive surgery.

Feedback module for evaluating optical-power stabilization methods

NASA Astrophysics Data System (ADS)

Downing, John

2016-03-01

A feedback module for evaluating the efficacy of optical-power stabilization without thermoelectric coolers (TECs) is described. The module comprises a pickoff optic for sampling a light beam, a photodiode for converting the sample power to electrical current, and a temperature sensor. The components are mounted on an optical bench that makes accurate (0.05°) beam alignment practical as well as providing high thermal-conductivity among the components. The module can be mounted on existing light sources or the components can be incorporated in new designs. Evaluations of optical and electronic stabilization methods are also reported. The optical method combines a novel, weakly reflective, weakly polarizing coating on the pickoff optic with a photodiode and an automatic-power-control (APC) circuit in a closed loop. The shift of emitter wavelength with temperature, coupled with the wavelength-dependent reflectance of the pickoff optic, enable the APC circuit to compensate for temperature errors. In the electronic method, a mixed-signal processor in a quasiclosed loop generates a control signal from temperature and photocurrent inputs and feeds it back to an APC circuit to compensate for temperature errors. These methods result in temperature coefficients less than 20 ppm/°C and relative rms power equal to 05% for the optical method and 0.02% for the electronic method. The later value represents an order of magnitude improvement over rms specifications for cooled, laser-diode modules and a five-fold improvement in wall-plug efficiency is achieved by eliminating TECs.

Imaging of ex vivo nonmelanoma skin cancers in the optical and terahertz spectral regions optical and terahertz skin cancers imaging.

PubMed

Joseph, Cecil S; Patel, Rakesh; Neel, Victor A; Giles, Robert H; Yaroslavsky, Anna N

2014-05-01

We tested the hypothesis that polarization sensitive optical and terahertz imaging may be combined for accurate nonmelanoma skin cancer (NMSC) delineation. Nine NMSC specimens were imaged. 513 μm and 440 nm wavelengths were used for terahertz and optical imaging, respectively. Histopathology was processed for evaluation. Terahertz reflectance of NMSC was quantified. Our results demonstrate that cross-polarized terahertz images correctly identified location of the tumours, whereas cross-polarized and polarization difference optical images accurately presented morphological features. Cross-polarized terahertz images exhibited lower reflectivity values in cancer as compared to normal tissue. Combination of optical and terahertz imaging shows promise for intraoperative delineation of NMSC. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Enhancing a slow and weak optomechanical nonlinearity with delayed quantum feedback

PubMed Central

Wang, Zhaoyou; Safavi-Naeini, Amir H.

2017-01-01

A central goal of quantum optics is to generate large interactions between single photons so that one photon can strongly modify the state of another one. In cavity optomechanics, photons interact with the motional degrees of freedom of an optical resonator, for example, by imparting radiation pressure forces on a movable mirror or sensing minute fluctuations in the position of the mirror. Here, we show that the optical nonlinearity arising from these effects, typically too small to operate on single photons, can be sufficiently enhanced with feedback to generate large interactions between single photons. We propose a protocol that allows photons propagating in a waveguide to interact with each other through multiple bounces off an optomechanical system. The protocol is analysed by evolving the full many-body quantum state of the waveguide-coupled system, illustrating that large photon–photon interactions mediated by mechanical motion may be within experimental reach. PMID:28677674

Power- or frequency-driven hysteresis for continuous-wave optically injected distributed-feedback semiconductor lasers.

PubMed

Blin, Stéphane; Vaudel, Olivier; Besnard, Pascal; Gabet, Renaud

2009-05-25

Bistabilities between a steady (or pulsating, chaotic) and different pulsating regimes are investigated for an optically injected semi-conductor laser. Both numerical and experimental studies are reported for continuous-wave single-mode semiconductor distributed-feedback lasers emitting at 1.55 microm. Hysteresis are driven by either changing the optically injected power or the frequency difference between both lasers. The effect of the injected laser pumping rate is also examined. Systematic mappings of the possible laser outputs (injection locking, bimodal, wave mixing, chaos or relaxation oscillations) are carried out. At small pumping rates (1.2 times threshold), only locking and bimodal regimes are observed. The extent of the bistable area is either 11 dB or 35 GHz, depending on the varying parameters. At high pumping rates (4 times threshold), numerous injection regimes are observed. Injection locking and its bistabilities are also reported for secondary longitudinal modes.

Enhancing a slow and weak optomechanical nonlinearity with delayed quantum feedback

NASA Astrophysics Data System (ADS)

Wang, Zhaoyou; Safavi-Naeini, Amir H.

2017-07-01

A central goal of quantum optics is to generate large interactions between single photons so that one photon can strongly modify the state of another one. In cavity optomechanics, photons interact with the motional degrees of freedom of an optical resonator, for example, by imparting radiation pressure forces on a movable mirror or sensing minute fluctuations in the position of the mirror. Here, we show that the optical nonlinearity arising from these effects, typically too small to operate on single photons, can be sufficiently enhanced with feedback to generate large interactions between single photons. We propose a protocol that allows photons propagating in a waveguide to interact with each other through multiple bounces off an optomechanical system. The protocol is analysed by evolving the full many-body quantum state of the waveguide-coupled system, illustrating that large photon-photon interactions mediated by mechanical motion may be within experimental reach.

Low-cost space-varying FIR filter architecture for computational imaging systems

NASA Astrophysics Data System (ADS)

Feng, Guotong; Shoaib, Mohammed; Schwartz, Edward L.; Dirk Robinson, M.

2010-01-01

Recent research demonstrates the advantage of designing electro-optical imaging systems by jointly optimizing the optical and digital subsystems. The optical systems designed using this joint approach intentionally introduce large and often space-varying optical aberrations that produce blurry optical images. Digital sharpening restores reduced contrast due to these intentional optical aberrations. Computational imaging systems designed in this fashion have several advantages including extended depth-of-field, lower system costs, and improved low-light performance. Currently, most consumer imaging systems lack the necessary computational resources to compensate for these optical systems with large aberrations in the digital processor. Hence, the exploitation of the advantages of the jointly designed computational imaging system requires low-complexity algorithms enabling space-varying sharpening. In this paper, we describe a low-cost algorithmic framework and associated hardware enabling the space-varying finite impulse response (FIR) sharpening required to restore largely aberrated optical images. Our framework leverages the space-varying properties of optical images formed using rotationally-symmetric optical lens elements. First, we describe an approach to leverage the rotational symmetry of the point spread function (PSF) about the optical axis allowing computational savings. Second, we employ a specially designed bank of sharpening filters tuned to the specific radial variation common to optical aberrations. We evaluate the computational efficiency and image quality achieved by using this low-cost space-varying FIR filter architecture.

Effect of Rayleigh-scattering distributed feedback on multiwavelength Raman fiber laser generation.

PubMed

El-Taher, A E; Harper, P; Babin, S A; Churkin, D V; Podivilov, E V; Ania-Castanon, J D; Turitsyn, S K

2011-01-15

We experimentally demonstrate a Raman fiber laser based on multiple point-action fiber Bragg grating reflectors and distributed feedback via Rayleigh scattering in an ~22-km-long optical fiber. Twenty-two lasing lines with spacing of ~100 GHz (close to International Telecommunication Union grid) in the C band are generated at the watt level. In contrast to the normal cavity with competition between laser lines, the random distributed feedback cavity exhibits highly stable multiwavelength generation with a power-equalized uniform distribution, which is almost independent on power.

Superconducting Microwave Multivibrator Produced by Coherent Feedback

NASA Astrophysics Data System (ADS)

Kerckhoff, Joseph; Lehnert, K. W.

2012-10-01

We investigate a nonlinear coherent feedback circuit constructed from preexisting superconducting microwave devices. The network exhibits emergent bistable and astable states, and we demonstrate its operation as a latch and the frequency locking of its oscillations. While the network is tedious to model by hand, our observations agree quite well with the semiclassical dynamical model produced by a new software package (N. Tezak , arXiv:1111.3081v1 [Phil. Trans. R. Soc. A (to be published)]) that systematically interpreted an idealized schematic of the system as a quantum optic feedback network.

PE-46 The Design of the Lynx X-Ray Microcalorimeter

NASA Technical Reports Server (NTRS)

Bandler, Simon; Dipirro, Michael; Eckart, Megan; Sakai, Kazuhiro; Smith, Stephen; Yoon, Wonsik; Bennett, Douglas; Kotsubo, Vincent; Mates, Benjamin; Swetz, Daneil;

Direct imaging of isofrequency contours in photonic structures

DOE PAGES

Regan, E. C.; Igarashi, Y.; Zhen, B.; ...

2016-11-25

The isofrequency contours of a photonic crystal are important for predicting and understanding exotic optical phenomena that are not apparent from high-symmetry band structure visualizations. We demonstrate a method to directly visualize the isofrequency contours of high-quality photonic crystal slabs that show quantitatively good agreement with numerical results throughout the visible spectrum. Our technique relies on resonance-enhanced photon scattering from generic fabrication disorder and surface roughness, so it can be applied to general photonic and plasmonic crystals or even quasi-crystals. We also present an analytical model of the scattering process, which explains the observation of isofrequency contours in our technique.more » Furthermore, the isofrequency contours provide information about the characteristics of the disorder and therefore serve as a feedback tool to improve fabrication processes.« less

Comparison of the Performance of Modal Control Schemes for an Adaptive Optics System and Analysis of the Effect of Actuator Limitations

DTIC Science & Technology

2012-06-01

the open-loop path is established, the feedback system can be treated as a set of SISO feedback loops and a single SISO control law can be applied...Zernike polynomials are commonly referred to by the names, such as focus, coma, astigmatism , and etc. Zernike polynomials can be transformed into

Surveillance system for air pollutants by combination of the decision support system COMPAS and optical remote sensing systems

NASA Astrophysics Data System (ADS)

Flassak, Thomas; de Witt, Helmut; Hahnfeld, Peter; Knaup, Andreas; Kramer, Lothar

1995-09-01

COMPAS is a decision support system designed to assist in the assessment of the consequences of accidental releases of toxic and flammable substances. One of the key elements of COMPAS is a feedback algorithm which allows us to calculate the source term with the aid of concentration measurements. Up to now the feedback technique is applied to concentration measurements done with test tubes or conventional point sensors. In this paper the extension of the actual method is presented which is the combination of COMPAS and an optical remote sensing system like the KAYSER-THREDE K300 FTIR system. Active remote sensing methods based on FTIR are, among other applications, ideal for the so-called fence line monitoring of the diffuse emissions and accidental releases from industrial facilities, since from the FTIR spectra averaged concentration levels along the measurement path can be achieved. The line-averaged concentrations are ideally suited as on-line input for COMPAS' feedback technique. Uncertainties in the assessment of the source term related with both shortcomings of the dispersion model itself and also problems of a feedback strategy based on point measurements are reduced.

Continuing quality improvement procedures for a clinical PACS.

PubMed

Andriole, K P; Gould, R G; Avrin, D E; Bazzill, T M; Yin, L; Arenson, R L

1998-08-01

The University of California at San Francisco (USCF) Department of Radiology currently has a clinically operational picture archiving and communication system (PACS) that is thirty-five percent filmless, with the goal of becoming seventy-five percent filmless within the year. The design and implementation of the clinical PACS has been a collaborative effort between an academic research laboratory and a commercial vendor partner. Images are digitally acquired from three computed radiography (CR) scanners, five computed tomography (CT) scanners, five magnetic resonance (MR) imagers, three digital fluoroscopic rooms, an ultrasound mini-PACS and a nuclear medicine mini-PACS. The DICOM (Digital Imaging and Communications in Medicine) standard communications protocol and image format is adhered to throughout the PACS. Images are archived in hierarchical staged fashion, on a RAID (redundant array of inexpensive disks) and on magneto-optical disk jukeboxes. The clinical PACS uses an object-oriented Oracle SQL (systems query language) database, and interfaces to the Radiology Information System using the HL7 (Health Languages 7) standard. Components are networked using a combination of switched and fast ethernet, and ATM (asynchronous transfer mode), all over fiber optics. The wide area network links six UCSF sites in San Francisco. A combination of high and medium resolution dual-monitor display stations have been placed throughout the Department of Radiology, the Emergency Department (ED) and Intensive Care Units (ICU). A continuing quality improvement (CQI) committee has been formed to facilitate the PACS installation and training, workflow modifications, quality assurance and clinical acceptance. This committee includes radiologists at all levels (resident, fellow, attending), radiology technologists, film library personnel, ED and ICU clinician end-users, and PACS team members. The CQI committee has proved vital in the creation of new management procedures, providing a means for user feedback and education, and contributing to the overall acceptance of, and user satisfaction with the system. Well developed CQI procedures have been essential to the successful clinical operation of the PACS as UCSF Radiology moves toward a filmless department.

Holistic feedback approach with video and peer discussion under teacher supervision.

PubMed

Hunukumbure, Agra Dilshani; Smith, Susan F; Das, Saroj

2017-09-29

High quality feedback is vital to learning in medical education but many students and teachers have expressed dissatisfaction on current feedback practices. Lack of teachers' insight into students' feedback requirements may be a key, which might be addressed by giving control to the students with student led feedback practices. The conceptual framework was built on three dimensions of learning theory by Illeris and Vygotsky's zone of proximal development and scaffolding. We introduced a feedback session with self-reflection and peer feedback in the form of open discussion on video-recorded student performances under teacher's guidance. The aims of this qualitative study were to explore students' perception on this holistic feedback approach and to investigate ways of maximising effective feedback and learning. Semi-structured interviews were used to gather data which were evaluated using a thematic analytical approach. The participants were third year medical students of Imperial College London on clinical placements at Hillingdon Hospital. Video based self-reflection helped some students to identify mistakes in communication and technical skills of which they were unaware prior to the session. Those who were new to video feedback found their expected self-image different to that of their actual image on video, leading to some distress. However many also identified that mistakes were not unique to themselves through peer videos and learnt from both model performances and from each other's mistakes. Balancing honest feedback with empathy was a challenge for many during peer discussion. The teacher played a vital role in making the session a success by providing guidance and a supportive environment. This study has demonstrated many potential benefits of this holistic feedback approach with video based self-reflection and peer discussion with students engaging at a deeper cognitive level than the standard descriptive feedback.

Efficient dynamic coherence transfer relying on offset locking using optical phase-locked loop

NASA Astrophysics Data System (ADS)

Xie, Weilin; Dong, Yi; Bretenaker, Fabien; Shi, Hongxiao; Zhou, Qian; Xia, Zongyang; Qin, Jie; Zhang, Lin; Lin, Xi; Hu, Weisheng

2018-01-01

We design and experimentally demonstrate a highly efficient coherence transfer based on composite optical phaselocked loop comprising multiple feedback servo loops. The heterodyne offset-locking is achieved by conducting an acousto-optic frequency shifter in combination with the current tuning and the temperature controlling of the semiconductor laser. The adaptation of the composite optical phase-locked loop enables the tight coherence transfer from a frequency comb to a semiconductor laser in a fully dynamic manner.

Enzyme activity assays within microstructured optical fibers enabled by automated alignment.

PubMed

Warren-Smith, Stephen C; Nie, Guiying; Schartner, Erik P; Salamonsen, Lois A; Monro, Tanya M

2012-12-01

A fluorescence-based enzyme activity assay has been demonstrated within a small-core microstructured optical fiber (MOF) for the first time. To achieve this, a reflection-based automated alignment system has been developed, which uses feedback and piezoelectric actuators to maintain optical alignment. The auto-alignment system provides optical stability for the time required to perform an activity assay. The chosen assay is based on the enzyme proprotein convertase 5/6 (PC6) and has important applications in women's health.

Valley-Selective Exciton Bistability in a Suspended Monolayer Semiconductor

NASA Astrophysics Data System (ADS)

Xie, Hongchao; Jiang, Shengwei; Shan, Jie; Mak, Kin Fai

2018-05-01

We demonstrate robust power- and wavelength-dependent optical bistability in fully suspended monolayers of WSe2 near the exciton resonance. Bistability has been achieved under continuous-wave optical excitation at an intensity level of 10^3 W/cm^2. The observed bistability is originated from a photo-thermal mechanism, which provides both optical nonlinearity and passive feedback, two essential elements for optical bistability. Under a finite magnetic field, the exciton bistability becomes helicity dependent, which enables repeatable switching of light purely by its polarization.

Mirrorless Optical Parametric Oscillation with Tunable Threshold in Cold Atoms.

PubMed

Mei, Yefeng; Guo, Xianxin; Zhao, Luwei; Du, Shengwang

2017-10-13

We report the demonstration of a mirrorless optical parametric oscillator with a tunable threshold in laser-cooled atoms with four-wave mixing (FWM) using electromagnetically induced transparency. Driven by two classical laser beams, the generated Stokes and anti-Stokes fields counterpropagate and build up efficient intrinsic feedback through the nonlinear FWM process. This feedback does not involve any cavity or spatially distributed microstructures. We observe the transition of photon correlation properties from the biphoton quantum regime (below the threshold) to the oscillation regime (above the threshold). The pump threshold can be tuned by varying the operating parameters. We achieve the oscillation with a threshold as low as 15  μW.

Amplitude Noise Reduction of Ion Lasers with Optical Feedback

NASA Technical Reports Server (NTRS)

Herring, Gregory C.

2011-01-01

A reduction in amplitude noise on the output of a multi-mode continuous-wave Ar-ion laser was previously demonstrated when a fraction of the output power was retroreflected back into the laser cavity. This result was reproduced in the present work and a Fabry-Perot etalon was used to monitor the longitudinal mode structure of the laser. A decrease in the number of operating longitudinal cavity modes was observed simultaneously with the introduction of the optical feedback and the onset of the amplitude noise reduction. The noise reduction is a result of a reduced number of lasing modes, resulting in less mode beating and amplitude fluctuations of the laser output power.

Fresnel zone plate light field spectral imaging simulation

NASA Astrophysics Data System (ADS)

Hallada, Francis D.; Franz, Anthony L.; Hawks, Michael R.

2017-05-01

Through numerical simulation, we have demonstrated a novel snapshot spectral imaging concept using binary diffractive optics. Binary diffractive optics, such as Fresnel zone plates (FZP) or photon sieves, can be used as the single optical element in a spectral imager that conducts both imaging and dispersion. In previous demonstrations of spectral imaging with diffractive optics, the detector array was physically translated along the optic axis to measure different image formation planes. In this new concept the wavelength-dependent images are constructed synthetically, by using integral photography concepts commonly applied to light field (plenoptic) cameras. Light field cameras use computational digital refocusing methods after exposure to make images at different object distances. Our concept refocuses to make images at different wavelengths instead of different object distances. The simulations in this study demonstrate this concept for an imager designed with a FZP. Monochromatic light from planar sources is propagated through the system to a measurement plane using wave optics in the Fresnel approximation. Simple images, placed at optical infinity, are illuminated by monochromatic sources and then digitally refocused to show different spectral bins. We show the formation of distinct images from different objects, illuminated by monochromatic sources in the VIS/NIR spectrum. Additionally, this concept could easily be applied to imaging in the MWIR and LWIR ranges. In conclusion, this new type of imager offers a rugged and simple optical design for snapshot spectral imaging and warrants further development.

Comparison of three ice cloud optical schemes in climate simulations with community atmospheric model version 5

NASA Astrophysics Data System (ADS)

Zhao, Wenjie; Peng, Yiran; Wang, Bin; Yi, Bingqi; Lin, Yanluan; Li, Jiangnan

2018-05-01

A newly implemented Baum-Yang scheme for simulating ice cloud optical properties is compared with existing schemes (Mitchell and Fu schemes) in a standalone radiative transfer model and in the global climate model (GCM) Community Atmospheric Model Version 5 (CAM5). This study systematically analyzes the effect of different ice cloud optical schemes on global radiation and climate by a series of simulations with a simplified standalone radiative transfer model, atmospheric GCM CAM5, and a comprehensive coupled climate model. Results from the standalone radiative model show that Baum-Yang scheme yields generally weaker effects of ice cloud on temperature profiles both in shortwave and longwave spectrum. CAM5 simulations indicate that Baum-Yang scheme in place of Mitchell/Fu scheme tends to cool the upper atmosphere and strengthen the thermodynamic instability in low- and mid-latitudes, which could intensify the Hadley circulation and dehydrate the subtropics. When CAM5 is coupled with a slab ocean model to include simplified air-sea interaction, reduced downward longwave flux to surface in Baum-Yang scheme mitigates ice-albedo feedback in the Arctic as well as water vapor and cloud feedbacks in low- and mid-latitudes, resulting in an overall temperature decrease by 3.0/1.4 °C globally compared with Mitchell/Fu schemes. Radiative effect and climate feedback of the three ice cloud optical schemes documented in this study can be referred for future improvements on ice cloud simulation in CAM5.

Ultracompact vibrometry measurement with nanometric accuracy using optical feedback

NASA Astrophysics Data System (ADS)

Jha, Ajit; Azcona, Francisco; Royo, Santiago

2015-05-01

The nonlinear dynamics of a semiconductor laser with optical feedback (OF) combined with direct current modulation of the laser is demonstrated to suffice for the measurement of subwavelength changes in the position of a vibrating object. So far, classical Optical Feedback Interferometry (OFI) has been used to measure the vibration of an object given its amplitude is greater than half the wavelength of emission, and the resolution of the measurement limited to some tenths of the wavelength after processing. We present here a methodology which takes advantage of the combination of two different phenomena: continuous wave frequency modulation (CWFM), induced by direct modulation of the laser, and non-linear dynamics inside of the laser cavity subject to optical self-injection (OSI). The methodology we propose shows how to detect vibration amplitudes smaller than half the emission wavelength with resolutions way beyond λ/2, extending the typical performance of OFI setups to very small amplitudes. A detailed mathematical model and simulation results are presented to support the proposed methodology, showing its ability to perform such displacement measurements of frequencies in the MHz range, depending upon the modulation frequency. Such approach makes the technique a suitable candidate, among other applications, to economic laser-based ultrasound measurements, with applications in nondestructive testing of materials (thickness, flaws, density, stresses), among others. The results of simulations of the proposed approach confirm the merit of the figures as detection of amplitudes of vibration below λ/2) with resolutions in the nanometer range.

Feedback-induced bistability of an optically levitated nanoparticle: A Fokker-Planck treatment

NASA Astrophysics Data System (ADS)

Ge, Wenchao; Rodenburg, Brandon; Bhattacharya, M.

2016-08-01

Optically levitated nanoparticles have recently emerged as versatile platforms for investigating macroscopic quantum mechanics and enabling ultrasensitive metrology. In this paper we theoretically consider two damping regimes of an optically levitated nanoparticle cooled by cavityless parametric feedback. Our treatment is based on a generalized Fokker-Planck equation derived from the quantum master equation presented recently and shown to agree very well with experiment [B. Rodenburg, L. P. Neukirch, A. N. Vamivakas, and M. Bhattacharya, Quantum model of cooling and force sensing with an optically trapped nanoparticle, Optica 3, 318 (2016), 10.1364/OPTICA.3.000318]. For low damping, we find that the resulting Wigner function yields the single-peaked oscillator position distribution and recovers the appropriate energy distribution derived earlier using a classical theory and verified experimentally [J. Gieseler, R. Quidant, C. Dellago, and L. Novotny, Dynamic relaxation of a levitated nanoparticle from a non-equilibrium steady state, Nat. Nano. 9, 358 (2014), 10.1038/nnano.2014.40]. For high damping, in contrast, we predict a double-peaked position distribution, which we trace to an underlying bistability induced by feedback. Unlike in cavity-based optomechanics, stochastic processes play a major role in determining the bistable behavior. To support our conclusions, we present analytical expressions as well as numerical simulations using the truncated Wigner function approach. Our work opens up the prospect of developing bistability-based devices, characterization of phase-space dynamics, and investigation of the quantum-classical transition using levitated nanoparticles.

Fiber-optic fluorescence imaging

PubMed Central

Flusberg, Benjamin A; Cocker, Eric D; Piyawattanametha, Wibool; Jung, Juergen C; Cheung, Eunice L M; Schnitzer, Mark J

2010-01-01

Optical fibers guide light between separate locations and enable new types of fluorescence imaging. Fiber-optic fluorescence imaging systems include portable handheld microscopes, flexible endoscopes well suited for imaging within hollow tissue cavities and microendoscopes that allow minimally invasive high-resolution imaging deep within tissue. A challenge in the creation of such devices is the design and integration of miniaturized optical and mechanical components. Until recently, fiber-based fluorescence imaging was mainly limited to epifluorescence and scanning confocal modalities. Two new classes of photonic crystal fiber facilitate ultrashort pulse delivery for fiber-optic two-photon fluorescence imaging. An upcoming generation of fluorescence imaging devices will be based on microfabricated device components. PMID:16299479

qF-SSOP: real-time optical property corrected fluorescence imaging

PubMed Central

Valdes, Pablo A.; Angelo, Joseph P.; Choi, Hak Soo; Gioux, Sylvain

2017-01-01

Fluorescence imaging is well suited to provide image guidance during resections in oncologic and vascular surgery. However, the distorting effects of tissue optical properties on the emitted fluorescence are poorly compensated for on even the most advanced fluorescence image guidance systems, leading to subjective and inaccurate estimates of tissue fluorophore concentrations. Here we present a novel fluorescence imaging technique that performs real-time (i.e., video rate) optical property corrected fluorescence imaging. We perform full field of view simultaneous imaging of tissue optical properties using Single Snapshot of Optical Properties (SSOP) and fluorescence detection. The estimated optical properties are used to correct the emitted fluorescence with a quantitative fluorescence model to provide quantitative fluorescence-Single Snapshot of Optical Properties (qF-SSOP) images with less than 5% error. The technique is rigorous, fast, and quantitative, enabling ease of integration into the surgical workflow with the potential to improve molecular guidance intraoperatively. PMID:28856038

INTERNATIONAL CONFERENCE ON SEMICONDUCTOR INJECTION LASERS SELCO-87: Continuous-wave distributed-feedback InGaAsP (λ = 1.55 μm) injection heterolasers

NASA Astrophysics Data System (ADS)

Baryshev, V. I.; Golikova, E. G.; Duraev, V. P.; Kuchinskiĭ, V. I.; Kizhaev, K. Yu; Kuksenkov, D. V.; Portnoĭ, E. L.; Smirnitskiĭ, V. B.

1988-11-01

A study was made of stimulated emission from mesa-stripe distributed-feedback lasers in the form of double heterostructures with separate electron and optical confinement. A diffraction grating with a period Λ = 0.46 μm, formed on the surface of the upper waveguide layer by holographic lithography, ensured distributed feedback in the second order. The threshold current for cw operation at room temperature was 35-70 mA, the shift of the emission wavelength with temperature was ~ 0.08 nm/K, and the feedback coefficient deduced from the width of a "Bragg gap" was 110-150 cm- 1.

Athermalization of resonant optical devices via thermo-mechanical feedback

DOEpatents

Rakich, Peter; Nielson, Gregory N.; Lentine, Anthony L.

2016-01-19

A passively athermal photonic system including a photonic circuit having a substrate and an optical cavity defined on the substrate, and passive temperature-responsive provisions for inducing strain in the optical cavity of the photonic circuit to compensate for a thermo-optic effect resulting from a temperature change in the optical cavity of the photonic circuit. Also disclosed is a method of passively compensating for a temperature dependent thermo-optic effect resulting on an optical cavity of a photonic circuit including the step of passively inducing strain in the optical cavity as a function of a temperature change of the optical cavity thereby producing an elasto-optic effect in the optical cavity to compensate for the thermo-optic effect resulting on an optical cavity due to the temperature change.

Wavefront measurement using computational adaptive optics.

PubMed

South, Fredrick A; Liu, Yuan-Zhi; Bower, Andrew J; Xu, Yang; Carney, P Scott; Boppart, Stephen A

2018-03-01

In many optical imaging applications, it is necessary to correct for aberrations to obtain high quality images. Optical coherence tomography (OCT) provides access to the amplitude and phase of the backscattered optical field for three-dimensional (3D) imaging samples. Computational adaptive optics (CAO) modifies the phase of the OCT data in the spatial frequency domain to correct optical aberrations without using a deformable mirror, as is commonly done in hardware-based adaptive optics (AO). This provides improvement of image quality throughout the 3D volume, enabling imaging across greater depth ranges and in highly aberrated samples. However, the CAO aberration correction has a complicated relation to the imaging pupil and is not a direct measurement of the pupil aberrations. Here we present new methods for recovering the wavefront aberrations directly from the OCT data without the use of hardware adaptive optics. This enables both computational measurement and correction of optical aberrations.

Metasurface optics for full-color computational imaging.

PubMed

Colburn, Shane; Zhan, Alan; Majumdar, Arka

2018-02-01

Conventional imaging systems comprise large and expensive optical components that successively mitigate aberrations. Metasurface optics offers a route to miniaturize imaging systems by replacing bulky components with flat and compact implementations. The diffractive nature of these devices, however, induces severe chromatic aberrations, and current multiwavelength and narrowband achromatic metasurfaces cannot support full visible spectrum imaging (400 to 700 nm). We combine principles of both computational imaging and metasurface optics to build a system with a single metalens of numerical aperture ~0.45, which generates in-focus images under white light illumination. Our metalens exhibits a spectrally invariant point spread function that enables computational reconstruction of captured images with a single digital filter. This work connects computational imaging and metasurface optics and demonstrates the capabilities of combining these disciplines by simultaneously reducing aberrations and downsizing imaging systems using simpler optics.

Real-time digital signal processing for live electro-optic imaging.

PubMed

Sasagawa, Kiyotaka; Kanno, Atsushi; Tsuchiya, Masahiro

2009-08-31

We present an imaging system that enables real-time magnitude and phase detection of modulated signals and its application to a Live Electro-optic Imaging (LEI) system, which realizes instantaneous visualization of RF electric fields. The real-time acquisition of magnitude and phase images of a modulated optical signal at 5 kHz is demonstrated by imaging with a Si-based high-speed CMOS image sensor and real-time signal processing with a digital signal processor. In the LEI system, RF electric fields are probed with light via an electro-optic crystal plate and downconverted to an intermediate frequency by parallel optical heterodyning, which can be detected with the image sensor. The artifacts caused by the optics and the image sensor characteristics are corrected by image processing. As examples, we demonstrate real-time visualization of electric fields from RF circuits.

Design of a multimodal fibers optic system for small animal optical imaging.

PubMed

Spinelli, Antonello E; Pagliazzi, Marco; Boschi, Federico

2015-02-01

Small animals optical imaging systems are widely used in pre-clinical research to image in vivo the bio-distribution of light emitting probes using fluorescence or bioluminescence modalities. In this work we presented a set of simulated results of a novel small animal optical imaging module based on a fibers optics matrix, coupled with a position sensitive detector, devoted to acquire bioluminescence and Cerenkov images. Simulations were performed using GEANT 4 code with the GAMOS architecture using the tissue optics plugin. Results showed that it is possible to image a 30 × 30 mm region of interest using a fiber optics array containing 100 optical fibers without compromising the quality of the reconstruction. The number of fibers necessary to cover an adequate portion of a small animal is thus quite modest. This design allows integrating the module with magnetic resonance (MR) in order to acquire optical and MR images at the same time. A detailed model of the mouse anatomy, obtained by segmentation of 3D MRI images, will improve the quality of optical 3D reconstruction. Copyright © 2014 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Improvement on vibration measurement performance of laser self-mixing interference by using a pre-feedback mirror

NASA Astrophysics Data System (ADS)

Zhu, Wei; Chen, Qianghua; Wang, Yanghong; Luo, Huifu; Wu, Huan; Ma, Binwu

2018-06-01

In the laser self-mixing interference vibration measurement system, the self mixing interference signal is usually weak so that it can be hardly distinguished from the environmental noise. In order to solve this problem, we present a self-mixing interference optical path with a pre-feedback mirror, a pre-feedback mirror is added between the object and the collimator lens, corresponding feedback light enters into the inner cavity of the laser and the interference by the pre-feedback mirror occurs. The pre-feedback system is established after that. The self-mixing interference theoretical model with a pre-feedback based on the F-P model is derived. The theoretical analysis shows that the amplitude of the intensity of the interference signal can be improved by 2-4 times. The influence factors of system are also discussed. The experiment results show that the amplitude of the signal is greatly improved, which agrees with the theoretical analysis.

The Stellar Populations of Two Ultra-diffuse Galaxies from Optical and Near-infrared Photometry

NASA Astrophysics Data System (ADS)

Pandya, Viraj; Romanowsky, Aaron J.; Laine, Seppo; Brodie, Jean P.; Johnson, Benjamin D.; Glaccum, William; Villaume, Alexa; Cuillandre, Jean-Charles; Gwyn, Stephen; Krick, Jessica; Lasker, Ronald; Martín-Navarro, Ignacio; Martinez-Delgado, David; van Dokkum, Pieter

2018-05-01

We present observational constraints on the stellar populations of two ultra-diffuse galaxies (UDGs) using optical through near-infrared (NIR) spectral energy distribution (SED) fitting. Our analysis is enabled by new Spitzer-IRAC 3.6 and 4.5 μm imaging, archival optical imaging, and the prospector fully Bayesian SED fitting framework. Our sample contains one field UDG (DGSAT I), one Virgo cluster UDG (VCC 1287), and one Virgo cluster dwarf elliptical for comparison (VCC 1122). We find that the optical–NIR colors of the three galaxies are significantly different from each other. We infer that VCC 1287 has an old (≳7.7 Gyr) and surprisingly metal-poor ([Z/Z ⊙] ≲ ‑1.0) stellar population, even after marginalizing over uncertainties on diffuse interstellar dust. In contrast, the field UDG DGSAT I shows evidence of being younger than the Virgo UDG, with an extended star formation history and an age posterior extending down to ∼3 Gyr. The stellar metallicity of DGSAT I is sub-solar but higher than that of the Virgo UDG, with [Z/{Z}ȯ ]=-{0.63}-0.62+0.35; in the case of exactly zero diffuse interstellar dust, DGSAT I may even have solar metallicity. With VCC 1287 and several Coma UDGs, a general picture is emerging where cluster UDGs may be “failed” galaxies, but the field UDG DGSAT I seems more consistent with a stellar feedback-induced expansion scenario. In the future, our approach can be applied to a large and diverse sample of UDGs down to faint surface brightness limits, with the goal of constraining their stellar ages, stellar metallicities, and circumstellar and diffuse interstellar dust content.

Optical alignment procedure utilizing neural networks combined with Shack-Hartmann wavefront sensor

NASA Astrophysics Data System (ADS)

Adil, Fatime Zehra; Konukseven, Erhan İlhan; Balkan, Tuna; Adil, Ömer Faruk

2017-05-01

In the design of pilot helmets with night vision capability, to not limit or block the sight of the pilot, a transparent visor is used. The reflected image from the coated part of the visor must coincide with the physical human sight image seen through the nonreflecting regions of the visor. This makes the alignment of the visor halves critical. In essence, this is an alignment problem of two optical parts that are assembled together during the manufacturing process. Shack-Hartmann wavefront sensor is commonly used for the determination of the misalignments through wavefront measurements, which are quantified in terms of the Zernike polynomials. Although the Zernike polynomials provide very useful feedback about the misalignments, the corrective actions are basically ad hoc. This stems from the fact that there exists no easy inverse relation between the misalignment measurements and the physical causes of the misalignments. This study aims to construct this inverse relation by making use of the expressive power of the neural networks in such complex relations. For this purpose, a neural network is designed and trained in MATLAB® regarding which types of misalignments result in which wavefront measurements, quantitatively given by Zernike polynomials. This way, manual and iterative alignment processes relying on trial and error will be replaced by the trained guesses of a neural network, so the alignment process is reduced to applying the counter actions based on the misalignment causes. Such a training requires data containing misalignment and measurement sets in fine detail, which is hard to obtain manually on a physical setup. For that reason, the optical setup is completely modeled in Zemax® software, and Zernike polynomials are generated for misalignments applied in small steps. The performance of the neural network is experimented and found promising in the actual physical setup.

NASA Tech Briefs, January 2003

NASA Technical Reports Server (NTRS)

2003-01-01

Topics covered include: Optoelectronic Tool Adds Scale Marks to Photographic Images; Compact Interconnection Networks Based on Quantum Dots; Laterally Coupled Quantum-Dot Distributed-Feedback Lasers; Bit-Serial Adder Based on Quantum Dots; Stabilized Fiber-Optic Distribution of Reference Frequency; Delay/Doppler-Mapping GPS-Reflection Remote-Sensing System; Ladar System Identifies Obstacles Partly Hidden by Grass; Survivable Failure Data Recorders for Spacecraft; Fiber-Optic Ammonia Sensors; Silicon Membrane Mirrors with Electrostatic Shape Actuators; Nanoscale Hot-Wire Probes for Boundary-Layer Flows; Theodolite with CCD Camera for Safe Measurement of Laser-Beam Pointing; Efficient Coupling of Lasers to Telescopes with Obscuration; Aligning Three Off-Axis Mirrors with Help of a DOE; Calibrating Laser Gas Measurements by Use of Natural CO2; Laser Ranging Simulation Program; Micro-Ball-Lens Optical Switch Driven by SMA Actuator; Evaluation of Charge Storage and Decay in Spacecraft Insulators; Alkaline Capacitors Based on Nitride Nanoparticles; Low-EC-Content Electrolytes for Low-Temperature Li-Ion Cells; Software for a GPS-Reflection Remote-Sensing System; Software for Building Models of 3D Objects via the Internet; "Virtual Cockpit Window" for a Windowless Aerospacecraft; CLARAty Functional-Layer Software; Java Library for Input and Output of Image Data and Metadata; Software for Estimating Costs of Testing Rocket Engines; Energy-Absorbing, Lightweight Wheels; Viscoelastic Vibration Dampers for Turbomachine Blades; Soft Landing of Spacecraft on Energy-Absorbing Self-Deployable Cushions; Pneumatically Actuated Miniature Peristaltic Vacuum Pumps; Miniature Gas-Turbine Power Generator; Pressure-Sensor Assembly Technique; Wafer-Level Membrane-Transfer Process for Fabricating MEMS; A Reactive-Ion Etch for Patterning Piezoelectric Thin Film; Wavelet-Based Real-Time Diagnosis of Complex Systems; Quantum Search in Hilbert Space; Analytic Method for Computing Instrument Pointing Jitter; and Semiselective Optoelectronic Sensors for Monitoring Microbes.

Multimodal Diffuse Optical Imaging

NASA Astrophysics Data System (ADS)

Intes, Xavier; Venugopal, Vivek; Chen, Jin; Azar, Fred S.

Diffuse optical imaging, particularly diffuse optical tomography (DOT), is an emerging clinical modality capable of providing unique functional information, at a relatively low cost, and with nonionizing radiation. Multimodal diffuse optical imaging has enabled a synergistic combination of functional and anatomical information: the quality of DOT reconstructions has been significantly improved by incorporating the structural information derived by the combined anatomical modality. In this chapter, we will review the basic principles of diffuse optical imaging, including instrumentation and reconstruction algorithm design. We will also discuss the approaches for multimodal imaging strategies that integrate DOI with clinically established modalities. The merit of the multimodal imaging approaches is demonstrated in the context of optical mammography, but the techniques described herein can be translated to other clinical scenarios such as brain functional imaging or muscle functional imaging.

Viscous optical clearing agent for in vivo optical imaging

NASA Astrophysics Data System (ADS)

Deng, Zijian; Jing, Lijia; Wu, Ning; lv, Pengyu; Jiang, Xiaoyun; Ren, Qiushi; Li, Changhui

2014-07-01

By allowing more photons to reach deeper tissue, the optical clearing agent (OCA) has gained increasing attention in various optical imaging modalities. However, commonly used OCAs have high fluidity, limiting their applications in in vivo studies with oblique, uneven, or moving surfaces. In this work, we reported an OCA with high viscosity. We measured the properties of this viscous OCA, and tested its successful performances in the imaging of a living animal's skin with two optical imaging modalities: photoacoustic microscopy and optical coherence tomography. Our results demonstrated that the viscous OCA has a great potential in the study of different turbid tissues using various optical imaging modalities.

The first high resolution image of coronal gas in a starbursting cool core cluster

NASA Astrophysics Data System (ADS)

Johnson, Sean

2017-08-01

Galaxy clusters represent a unique laboratory for directly observing gas cooling and feedback due to their high masses and correspondingly high gas densities and temperatures. Cooling of X-ray gas observed in 1/3 of clusters, known as cool-core clusters, should fuel star formation at prodigious rates, but such high levels of star formation are rarely observed. Feedback from active galactic nuclei (AGN) is a leading explanation for the lack of star formation in most cool clusters, and AGN power is sufficient to offset gas cooling on average. Nevertheless, some cool core clusters exhibit massive starbursts indicating that our understanding of cooling and feedback is incomplete. Observations of 10^5 K coronal gas in cool core clusters through OVI emission offers a sensitive means of testing our understanding of cooling and feedback because OVI emission is a dominant coolant and sensitive tracer of shocked gas. Recently, Hayes et al. 2016 demonstrated that synthetic narrow-band imaging of OVI emission is possible through subtraction of long-pass filters with the ACS+SBC for targets at z=0.23-0.29. Here, we propose to use this exciting new technique to directly image coronal OVI emitting gas at high resolution in Abell 1835, a prototypical starbursting cool-core cluster at z=0.252. Abell 1835 hosts a strong cooling core, massive starburst, radio AGN, and at z=0.252, it offers a unique opportunity to directly image OVI at hi-res in the UV with ACS+SBC. With just 15 orbits of ACS+SBC imaging, the proposed observations will complete the existing rich multi-wavelength dataset available for Abell 1835 to provide new insights into cooling and feedback in clusters.

Grating exchange system of independent mirror supported by floating rotary stage

NASA Astrophysics Data System (ADS)

Zhang, Jianhuan; Tao, Jin; Liu, Yan; Nan, Yan

2015-10-01

The performance of The Grating Exchange System can satisfy the Thirty Meter Telescope - TMT for astronomical observation WFOS index requirements and satisfy the requirement of accuracy in the grating exchange. It is used to install in the MOBIE and a key device of MOBIE. The Wide Field Optical Spectrograph (WFOS) is one of the three first-light observing capabilities selected by the TMT Science Advisory Committee. The Multi-Object Broadband Imaging Echellette (MOBIE) instrument design concept has been developed to address the WFOS requirements as described in the TMT Science-Based Requirements Document (SRD). The Grating Exchange System uses a new type of separate movement way of three grating devices and a mirror device. Three grating devices with a mirror are able to achieve independence movement. This kind of grating exchange system can effectively solve the problem that the volume of the grating change system is too large and that the installed space of MOBIE instruments is too limit. This system adopts the good stability, high precision of rotary stage - a kind of using air bearing (Air bearing is famous for its ultra-high precision, and can meet the optical accuracy requirement) and rotation positioning feedback gauge turntable to support grating device. And with a kind of device which can carry greater weight bracket fixed on the MOBIE instrument, with two sets of servo motor control rotary stage and the mirror device respectively. And we use the control program to realize the need of exercising of the grating device and the mirror device. Using the stress strain analysis software--SolidWorks for stress and strain analysis of this structure. And then checking the structure of the rationality and feasibility. And prove that this system can realize the positioning precision under different working conditions can meet the requirements of imaging optical grating diffraction efficiency and error by the calculation and optical performance analysis.

SEM based overlay measurement between resist and buried patterns

NASA Astrophysics Data System (ADS)

Inoue, Osamu; Okagawa, Yutaka; Hasumi, Kazuhisa; Shao, Chuanyu; Leray, Philippe; Lorusso, Gian; Baudemprez, Bart

2016-03-01

With the continuous shrink in pattern size and increased density, overlay control has become one of the most critical issues in semiconductor manufacturing. Recently, SEM based overlay of AEI (After Etch Inspection) wafer has been used for reference and optimization of optical overlay (both Image Based Overlay (IBO) and Diffraction Based Overlay (DBO)). Overlay measurement at AEI stage contributes monitor and forecast the yield after formation by etch and calibrate optical measurement tools. however those overlay value seems difficult directly for feedback to a scanner. Therefore, there is a clear need to have SEM based overlay measurements of ADI (After Develop Inspection) wafers in order to serve as reference for optical overlay and make necessary corrections before wafers go to etch. Furthermore, to make the corrections as accurate as possible, actual device like feature dimensions need to be measured post ADI. This device size measurement is very unique feature of CDSEM , which can be measured with smaller area. This is currently possible only with the CD-SEM. This device size measurement is very unique feature of CD-SEM , which can be measured with smaller area. In this study, we assess SEM based overlay measurement of ADI and AEI wafer by using a sample from an N10 process flow. First, we demonstrate SEM based overlay performance at AEI by using dual damascene process for Via 0 (V0) and metal 1 (M1) layer. We also discuss the overlay measurements between litho-etch-litho stages of a triple patterned M1 layer and double pattern V0. Second, to illustrate the complexities in image acquisition and measurement we will measure overlay between M1B resist and buried M1A-Hard mask trench. Finally, we will show how high accelerating voltage can detect buried pattern information by BSE (Back Scattering Electron). In this paper we discuss the merits of this method versus standard optical metrology based corrections.

Complete analog control of the carrier-envelope-phase of a high-power laser amplifier.

PubMed

Feng, C; Hergott, J-F; Paul, P-M; Chen, X; Tcherbakoff, O; Comte, M; Gobert, O; Reduzzi, M; Calegari, F; Manzoni, C; Nisoli, M; Sansone, G

2013-10-21

In this work we demonstrate the development of a complete analog feedback loop for the control of the carrier-envelope phase (CEP) of a high-average power (20 W) laser operating at 10 kHz repetition rate. The proposed method combines a detection scheme working on a single-shot basis at the full-repetition-rate of the laser system with a fast actuator based either on an acousto-optic or on an electro-optic crystal. The feedback loop is used to correct the CEP fluctuations introduced by the amplification process demonstrating a CEP residual noise of 320 mrad measured on a single-shot basis. The comparison with a feedback loop operating at a lower sampling rate indicates an improvement up to 45% in the residual noise. The measurement of the CEP drift for different integration times clearly evidences the importance of the single-shot characterization of the residual CEP drift. The demonstrated scheme could be efficiently applied for systems approaching the 100 kHz repetition rate regime.

Active browsing using similarity pyramids

NASA Astrophysics Data System (ADS)

Chen, Jau-Yuen; Bouman, Charles A.; Dalton, John C.

1998-12-01

In this paper, we describe a new approach to managing large image databases, which we call active browsing. Active browsing integrates relevance feedback into the browsing environment, so that users can modify the database's organization to suit the desired task. Our method is based on a similarity pyramid data structure, which hierarchically organizes the database, so that it can be efficiently browsed. At coarse levels, the similarity pyramid allows users to view the database as large clusters of similar images. Alternatively, users can 'zoom into' finer levels to view individual images. We discuss relevance feedback for the browsing process, and argue that it is fundamentally different from relevance feedback for more traditional search-by-query tasks. We propose two fundamental operations for active browsing: pruning and reorganization. Both of these operations depend on a user-defined relevance set, which represents the image or set of images desired by the user. We present statistical methods for accurately pruning the database, and we propose a new 'worm hole' distance metric for reorganizing the database, so that members of the relevance set are grouped together.

Effect of multiple circular holes Fraunhofer diffraction for the infrared optical imaging

NASA Astrophysics Data System (ADS)

Lu, Chunlian; Lv, He; Cao, Yang; Cai, Zhisong; Tan, Xiaojun

2014-11-01

With the development of infrared optics, infrared optical imaging systems play an increasingly important role in modern optical imaging systems. Infrared optical imaging is used in industry, agriculture, medical, military and transportation. But in terms of infrared optical imaging systems which are exposed for a long time, some contaminations will affect the infrared optical imaging. When the contamination contaminate on the lens surface of the optical system, it would affect diffraction. The lens can be seen as complementary multiple circular holes screen happen Fraunhofer diffraction. According to Babinet principle, you can get the diffraction of the imaging system. Therefore, by studying the multiple circular holes Fraunhofer diffraction, conclusions can be drawn about the effect of infrared imaging. This paper mainly studies the effect of multiple circular holes Fraunhofer diffraction for the optical imaging. Firstly, we introduce the theory of Fraunhofer diffraction and Point Spread Function. Point Spread Function is a basic tool to evaluate the image quality of the optical system. Fraunhofer diffraction will affect Point Spread Function. Then, the results of multiple circular holes Fraunhofer diffraction are given for different hole size and hole spacing. We choose the hole size from 0.1mm to 1mm and hole spacing from 0.3mm to 0.8mm. The infrared wavebands of optical imaging are chosen from 1μm to 5μm. We use the MATLAB to simulate light intensity distribution of multiple circular holes Fraunhofer diffraction. Finally, three-dimensional diffraction maps of light intensity are given to contrast.

Fiber optic in vivo imaging in the mammalian nervous system

PubMed Central

Mehta, Amit D; Jung, Juergen C; Flusberg, Benjamin A; Schnitzer, Mark J

2010-01-01

The compact size, mechanical flexibility, and growing functionality of optical fiber and fiber optic devices are enabling several new modalities for imaging the mammalian nervous system in vivo. Fluorescence microendoscopy is a minimally invasive fiber modality that provides cellular resolution in deep brain areas. Diffuse optical tomography is a non-invasive modality that uses assemblies of fiber optic emitters and detectors on the cranium for volumetric imaging of brain activation. Optical coherence tomography is a sensitive interferometric imaging technique that can be implemented in a variety of fiber based formats and that might allow intrinsic optical detection of brain activity at a high resolution. Miniaturized fiber optic microscopy permits cellular level imaging in the brains of behaving animals. Together, these modalities will enable new uses of imaging in the intact nervous system for both research and clinical applications. PMID:15464896

Lens implementation on the GATE Monte Carlo toolkit for optical imaging simulation

NASA Astrophysics Data System (ADS)

Kang, Han Gyu; Song, Seong Hyun; Han, Young Been; Kim, Kyeong Min; Hong, Seong Jong

2018-02-01

Optical imaging techniques are widely used for in vivo preclinical studies, and it is well known that the Geant4 Application for Emission Tomography (GATE) can be employed for the Monte Carlo (MC) modeling of light transport inside heterogeneous tissues. However, the GATE MC toolkit is limited in that it does not yet include optical lens implementation, even though this is required for a more realistic optical imaging simulation. We describe our implementation of a biconvex lens into the GATE MC toolkit to improve both the sensitivity and spatial resolution for optical imaging simulation. The lens implemented into the GATE was validated against the ZEMAX optical simulation using an US air force 1951 resolution target. The ray diagrams and the charge-coupled device images of the GATE optical simulation agreed with the ZEMAX optical simulation results. In conclusion, the use of a lens on the GATE optical simulation could improve the image quality of bioluminescence and fluorescence significantly as compared with pinhole optics.

Optical cryptography with biometrics for multi-depth objects.

PubMed

Yan, Aimin; Wei, Yang; Hu, Zhijuan; Zhang, Jingtao; Tsang, Peter Wai Ming; Poon, Ting-Chung

2017-10-11

We propose an optical cryptosystem for encrypting images of multi-depth objects based on the combination of optical heterodyne technique and fingerprint keys. Optical heterodyning requires two optical beams to be mixed. For encryption, each optical beam is modulated by an optical mask containing either the fingerprint of the person who is sending, or receiving the image. The pair of optical masks are taken as the encryption keys. Subsequently, the two beams are used to scan over a multi-depth 3-D object to obtain an encrypted hologram. During the decryption process, each sectional image of the 3-D object is recovered by convolving its encrypted hologram (through numerical computation) with the encrypted hologram of a pinhole image that is positioned at the same depth as the sectional image. Our proposed method has three major advantages. First, the lost-key situation can be avoided with the use of fingerprints as the encryption keys. Second, the method can be applied to encrypt 3-D images for subsequent decrypted sectional images. Third, since optical heterodyning scanning is employed to encrypt a 3-D object, the optical system is incoherent, resulting in negligible amount of speckle noise upon decryption. To the best of our knowledge, this is the first time optical cryptography of 3-D object images has been demonstrated in an incoherent optical system with biometric keys.

Ultrasound Images of the Tongue: A Tutorial for Assessment and Remediation of Speech Sound Errors.

PubMed

Preston, Jonathan L; McAllister Byun, Tara; Boyce, Suzanne E; Hamilton, Sarah; Tiede, Mark; Phillips, Emily; Rivera-Campos, Ahmed; Whalen, Douglas H

2017-01-03

Diagnostic ultrasound imaging has been a common tool in medical practice for several decades. It provides a safe and effective method for imaging structures internal to the body. There has been a recent increase in the use of ultrasound technology to visualize the shape and movements of the tongue during speech, both in typical speakers and in clinical populations. Ultrasound imaging of speech has greatly expanded our understanding of how sounds articulated with the tongue (lingual sounds) are produced. Such information can be particularly valuable for speech-language pathologists. Among other advantages, ultrasound images can be used during speech therapy to provide (1) illustrative models of typical (i.e. "correct") tongue configurations for speech sounds, and (2) a source of insight into the articulatory nature of deviant productions. The images can also be used as an additional source of feedback for clinical populations learning to distinguish their better productions from their incorrect productions, en route to establishing more effective articulatory habits. Ultrasound feedback is increasingly used by scientists and clinicians as both the expertise of the users increases and as the expense of the equipment declines. In this tutorial, procedures are presented for collecting ultrasound images of the tongue in a clinical context. We illustrate these procedures in an extended example featuring one common error sound, American English /r/. Images of correct and distorted /r/ are used to demonstrate (1) how to interpret ultrasound images, (2) how to assess tongue shape during production of speech sounds, (3), how to categorize tongue shape errors, and (4), how to provide visual feedback to elicit a more appropriate and functional tongue shape. We present a sample protocol for using real-time ultrasound images of the tongue for visual feedback to remediate speech sound errors. Additionally, example data are shown to illustrate outcomes with the procedure.

Electron-Focus Adjustment for Photo-Optical Imagers

NASA Technical Reports Server (NTRS)

Fowler, Walter B.; Flemming, Keith; Ziegler, Michael M.

1987-01-01

Internal electron focus made independent of optical focus. Procedure enables fine tuning of internal electron-focusing system of photo-optical imager, without complication by imperfections of associated external optics. Applicable to imager in which electrons emitted from photocathode in optical focal plane, then electrostatically and/or magnetically focused to replica of image in second focal plane containing photodiodes, phototransistorss, charge-coupled devices, multiple-anode outputs, or other detectors.

Effects of pipette modulation and imaging distances on ion currents measured with scanning ion conductance microscopy (SICM).

PubMed

Chen, Chiao-Chen; Baker, Lane A

2011-01-07

Local conductance variations can be estimated by measuring ion current magnitudes with scanning ion conductance microscopy (SICM). Factors which influence image quality and quantitation of ion currents measured with SICM have been evaluated. Specifically, effects of probe-sample separation and pipette modulation have been systematically studied for the case of imaging conductance variations at pores in a polymer membrane under transmembrane concentration gradients. The influence of probe-sample separation on ion current images was evaluated using distance-modulated (ac) feedback. Approach curves obtained using non-modulated (dc) feedback were also recorded to determine the relative influence of pipette-generated convection by comparison of ion currents measured with both ac and dc feedback modes. To better interpret results obtained, comparison to a model based on a disk-shaped geometry for nanopores in the membrane, as well as relevant position-dependent parameters of the experiment is described. These results advance our current understanding of conductance measurements with SICM.

Carbon nanotube based respiratory gated micro-CT imaging of a murine model of lung tumors with optical imaging correlation

NASA Astrophysics Data System (ADS)

Burk, Laurel M.; Lee, Yueh Z.; Heathcote, Samuel; Wang, Ko-han; Kim, William Y.; Lu, Jianping; Zhou, Otto

2011-03-01

Current optical imaging techniques can successfully measure tumor load in murine models of lung carcinoma but lack structural detail. We demonstrate that respiratory gated micro-CT imaging of such models gives information about structure and correlates with tumor load measurements by optical methods. Four mice with multifocal, Kras-induced tumors expressing firefly luciferase were imaged against four controls using both optical imaging and respiratory gated micro-CT. CT images of anesthetized animals were acquired with a custom CNT-based system using 30 ms x-ray pulses during peak inspiration; respiration motion was tracked with a pressure sensor beneath each animal's abdomen. Optical imaging based on the Luc+ signal correlating with tumor load was performed on a Xenogen IVIS Kinetix. Micro-CT images were post-processed using Osirix, measuring lung volume with region growing. Diameters of the largest three tumors were measured. Relationships between tumor size, lung volumes, and optical signal were compared. CT images and optical signals were obtained for all animals at two time points. In all lobes of the Kras+ mice in all images, tumors were visible; the smallest to be readily identified measured approximately 300 microns diameter. CT-derived tumor volumes and optical signals related linearly, with r=0.94 for all animals. When derived for only tumor bearing animals, r=0.3. The trend of each individual animal's optical signal tracked correctly based on the CT volumes. Interestingly, lung volumes also correlated positively with optical imaging data and tumor volume burden, suggesting active remodeling.

Binocular and Monocular Depth Cues in Online Feedback Control of 3-D Pointing Movement

PubMed Central

Hu, Bo; Knill, David C.

2012-01-01

Previous work has shown that humans continuously use visual feedback of the hand to control goal-directed movements online. In most studies, visual error signals were predominantly in the image plane and thus were available in an observer’s retinal image. We investigate how humans use visual feedback about finger depth provided by binocular and monocular depth cues to control pointing movements. When binocularly viewing a scene in which the hand movement was made in free space, subjects were about 60 ms slower in responding to perturbations in depth than in the image plane. When monocularly viewing a scene designed to maximize the available monocular cues to finger depth (motion, changing size and cast shadows), subjects showed no response to perturbations in depth. Thus, binocular cues from the finger are critical to effective online control of hand movements in depth. An optimal feedback controller that takes into account of the low peripheral stereoacuity and inherent ambiguity in cast shadows can explain the difference in response time in the binocular conditions and lack of response in monocular conditions. PMID:21724567

Utility of Digital Stereo Images for Optic Disc Evaluation

PubMed Central

Ying, Gui-shuang; Pearson, Denise J.; Bansal, Mayank; Puri, Manika; Miller, Eydie; Alexander, Judith; Piltz-Seymour, Jody; Nyberg, William; Maguire, Maureen G.; Eledath, Jayan; Sawhney, Harpreet

2010-01-01

Purpose. To assess the suitability of digital stereo images for optic disc evaluations in glaucoma. Methods. Stereo color optic disc images in both digital and 35-mm slide film formats were acquired contemporaneously from 29 subjects with various cup-to-disc ratios (range, 0.26–0.76; median, 0.475). Using a grading scale designed to assess image quality, the ease of visualizing optic disc features important for glaucoma diagnosis, and the comparative diameters of the optic disc cup, experienced observers separately compared the primary digital stereo images to each subject's 35-mm slides, to scanned images of the same 35-mm slides, and to grayscale conversions of the digital images. Statistical analysis accounted for multiple gradings and comparisons and also assessed image formats under monoscopic viewing. Results. Overall, the quality of primary digital color images was judged superior to that of 35-mm slides (P < 0.001), including improved stereo (P < 0.001), but the primary digital color images were mostly equivalent to the scanned digitized images of the same slides. Color seemingly added little to grayscale optic disc images, except that peripapillary atrophy was best seen in color (P < 0.0001); both the nerve fiber layer (P < 0.0001) and the paths of blood vessels on the optic disc (P < 0.0001) were best seen in grayscale. The preference for digital over film images was maintained under monoscopic viewing conditions. Conclusions. Digital stereo optic disc images are useful for evaluating the optic disc in glaucoma and allow the application of advanced image processing applications. Grayscale images, by providing luminance distinct from color, may be informative for assessing certain features. PMID:20505199

The New Physical Optics Notebook: Tutorials in Fourier Optics.

ERIC Educational Resources Information Center

Reynolds, George O.; And Others

This is a textbook of Fourier optics for the classroom or self-study. Major topics included in the 38 chapters are: Huygens' principle and Fourier transforms; image formation; optical coherence theory; coherent imaging; image analysis; coherent noise; interferometry; holography; communication theory techniques; analog optical computing; phase…

Combined magnetic resonance, fluorescence, and histology imaging strategy in a human breast tumor xenograft model

PubMed Central

Jiang, Lu; Greenwood, Tiffany R.; Amstalden van Hove, Erika R.; Chughtai, Kamila; Raman, Venu; Winnard, Paul T.; Heeren, Ron; Artemov, Dmitri; Glunde, Kristine

2014-01-01

Applications of molecular imaging in cancer and other diseases frequently require combining in vivo imaging modalities, such as magnetic resonance and optical imaging, with ex vivo optical, fluorescence, histology, and immunohistochemical (IHC) imaging, to investigate and relate molecular and biological processes to imaging parameters within the same region of interest. We have developed a multimodal image reconstruction and fusion framework that accurately combines in vivo magnetic resonance imaging (MRI) and magnetic resonance spectroscopic imaging (MRSI), ex vivo brightfield and fluorescence microscopic imaging, and ex vivo histology imaging. Ex vivo brightfield microscopic imaging was used as an intermediate modality to facilitate the ultimate link between ex vivo histology and in vivo MRI/MRSI. Tissue sectioning necessary for optical and histology imaging required generation of a three-dimensional (3D) reconstruction module for 2D ex vivo optical and histology imaging data. We developed an external fiducial marker based 3D reconstruction method, which was able to fuse optical brightfield and fluorescence with histology imaging data. Registration of 3D tumor shape was pursued to combine in vivo MRI/MRSI and ex vivo optical brightfield and fluorescence imaging data. This registration strategy was applied to in vivo MRI/MRSI, ex vivo optical brightfield/fluorescence, as well as histology imaging data sets obtained from human breast tumor models. 3D human breast tumor data sets were successfully reconstructed and fused with this platform. PMID:22945331

A phase space approach to imaging from limited data

NASA Astrophysics Data System (ADS)

Testorf, Markus E.

2015-09-01

The optical instrument function is used as the basis to develop optical system theory for imaging applications. The detection of optical signals is conveniently described as the overlap integral of the Wigner distribution functions of instrument and optical signal. Based on this framework various optical imaging systems, including plenoptic cameras, phase-retrieval algorithms, and Shack-Hartman sensors are shown to acquire information about a domain in phase-space, with finite extension and finite resolution. It is demonstrated how phase space optics can be used both to analyze imaging systems, as well as for designing methods for image reconstruction.