Lorain Harbor, Ohio. Preliminary Feasibility Study (Stage 2). Review of Reports. Volume 1. Main Report.

DTIC Science & Technology

1980-10-01

May 1980 Dollars) 93 32 Apportionment of Total Project Cost for Alternative 1, Option 1 (1,000-Footer) 94 33 Estimated Investment Cost and Annual...Costs - Alternative 2, Option 1 (1,000-Foot Vessels) (May 1980 Dollars) 101 36 Apportionment of Total Project Cost for Alternative 2, Option 1 (1,000...1 (1,000-Footer) 104 39 Estimate of Navigation Project Codes - Alternative 3, Option 1 (1,000-Foot Vessels) (May 1980 Dollars) 107 40 Apportionment of

Inertial Fusion Energy reactor design studies: Prometheus-L, Prometheus-H. Volume 2, Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waganer, L.M.; Driemeyer, D.E.; Lee, V.D.

1992-03-01

This report contains a review of design studies for Inertial Confinement reactor. This second of three volumes discussions is some detail the following: Objectives, requirements, and assumptions; rationale for design option selection; key technical issues and R&D requirements; and conceptual design selection and description.

Study of Automobile Market Dynamics : Volume 2. Analysis.

DOT National Transportation Integrated Search

1977-08-01

Volume II describes the work in providing statistical inputs to a computer model by examining the effects of various options on the number of automobiles sold; the distribution of sales among small, medium and large cars; the distribution between aut...

Energy conservation policy evaluation. Study module IA. Volume II. Technical appendix. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bergstresser, K.; Berney, R.E.; Carter, L.F.

1978-01-01

This volume contains detailed technical analyses of the 19 energy conservation measures which were discussed as regional policy options in the report proper (PB-274 337). For each measure there is a description of how the measure works to reduce consumption; an assessment of potential savings, costs, and returns to adopters; probable 'normal' adoption rates under present policies; and potential adoption rates if some additional conservation policy options are implemented. Report includes chapters on environmental residuals from energy end uses, and policy preferences of households and energy marketers.

78 FR 14597 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-06

... assessed different fees than other indexes.\\21\\ In addition, the concept of offering a volume discount to.... This volume discount on trading Options on Treasury Securities will serve to increase order flow, which... options transaction charge. It is also reasonable and equitable to offer a floor volume discount on...

Spacelab Level 4 Programmatic Implementation Assessment Study. Volume 4: Executive summary

NASA Technical Reports Server (NTRS)

1978-01-01

The study objectives of the Spacelab level 4 analysis were defined, along with the most significant results. The approach used in the synthesis and selection of alternate level 4 integration is described; the options included distributed site, lead center, and launch site. Principal characteristics, as well as the functional flow diagrams for each option, are presented and explained.

78 FR 54507 - Clearing Agency; the Options Clearing Corporation; Notice of Filing of Proposed Rule Change To...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-04

... outstanding shareholders and overall trading volume. The STANS system currently takes into account the risk to... volume). If the net long position in the account, as adjusted for the delta of short option and futures..., particularly where the average daily trading volume of the deposited security is low, while taking into account...

Space station needs, attributes and architectural options: Architectural options and selection

NASA Technical Reports Server (NTRS)

Nelson, W. G.

1983-01-01

The approach, study results, and recommendations for defining and selecting space station architectural options are described. Space station system architecture is defined as the arrangement of elements (manned and unmanned on-orbit facilities, shuttle vehicles, orbital transfer vehicles, etc.), the number of these elements, their location (orbital inclination and altitude, and their functional performance capability, power, volume, crew, etc.). Architectural options are evaluated based on the degree of mission capture versus cost and required funding rate. Mission capture refers to the number of missions accommodated by the particular architecture.

A study of space station needs, attributes and architectural options. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Steinbronn, O.

1983-01-01

Missions that will benefit from the development of a permanent manned space station are examined. The missions that will determine the space station architecture include spaceborne scientific experiments, space industrialization and commercialization, remote space operations, and U.S. national security. Architectural options and economic analysis are also presented.

The 25 kW power module evolution study. Part 3: Conceptual designs for power module evolution. Volume 4: Design analyses

NASA Technical Reports Server (NTRS)

1979-01-01

Topics covered include growth options evaluation, mass properties, attitude control and structural dynamics, contamination evaluation, berthing concepts, orbit reboost options and growth kit concepts. Systems support elements and space support equipment are reviewed with emphasis on power module operations and technology planning.

40 CFR Table 3 to Subpart II of... - Summary of Recordkeeping and Reporting Requirements abc

Code of Federal Regulations, 2012 CFR

2012-07-01

... abc Requirement All Opts. Rec Rep Option 1 Rec Rep Option 2 Rec Rep Option 3 Rec Rep Notification (§ 63.9(a)-(d)) X X Implementation plan (§ 63.787(b)) d X X Volume of coating applied at unaffected major sources (§ 63.781(b)) X Volume of each low-usage-exempt coating applied at affected sources (§ 63...

40 CFR Table 3 to Subpart II of... - Summary of Recordkeeping and Reporting Requirements abc

Code of Federal Regulations, 2011 CFR

2011-07-01

... abc Requirement All Opts. Rec Rep Option 1 Rec Rep Option 2 Rec Rep Option 3 Rec Rep Notification (§ 63.9(a)-(d)) X X Implementation plan (§ 63.787(b)) d X X Volume of coating applied at unaffected major sources (§ 63.781(b)) X Volume of each low-usage-exempt coating applied at affected sources (§ 63...

40 CFR Table 3 to Subpart II of... - Summary of Recordkeeping and Reporting Requirements abc

Code of Federal Regulations, 2010 CFR

2010-07-01

... abc Requirement All Opts. Rec Rep Option 1 Rec Rep Option 2 Rec Rep Option 3 Rec Rep Notification (§ 63.9(a)-(d)) X X Implementation plan (§ 63.787(b)) d X X Volume of coating applied at unaffected major sources (§ 63.781(b)) X Volume of each low-usage-exempt coating applied at affected sources (§ 63...

40 CFR Table 3 to Subpart II of... - Summary of Recordkeeping and Reporting Requirements abc

Code of Federal Regulations, 2013 CFR

2013-07-01

... abc Requirement All Opts. Rec Rep Option 1 Rec Rep Option 2 Rec Rep Option 3 Rec Rep Notification (§ 63.9(a)-(d)) X X Implementation plan (§ 63.787(b)) d X X Volume of coating applied at unaffected major sources (§ 63.781(b)) X Volume of each low-usage-exempt coating applied at affected sources (§ 63...

40 CFR Table 3 to Subpart II of... - Summary of Recordkeeping and Reporting Requirements abc

Code of Federal Regulations, 2014 CFR

2014-07-01

... abc Requirement All Opts. Rec Rep Option 1 Rec Rep Option 2 Rec Rep Option 3 Rec Rep Notification (§ 63.9(a)-(d)) X X Implementation plan (§ 63.787(b)) d X X Volume of coating applied at unaffected major sources (§ 63.781(b)) X Volume of each low-usage-exempt coating applied at affected sources (§ 63...

Finite Volume Method for Pricing European Call Option with Regime-switching Volatility

NASA Astrophysics Data System (ADS)

Lista Tauryawati, Mey; Imron, Chairul; Putri, Endah RM

2018-03-01

In this paper, we present a finite volume method for pricing European call option using Black-Scholes equation with regime-switching volatility. In the first step, we formulate the Black-Scholes equations with regime-switching volatility. we use a finite volume method based on fitted finite volume with spatial discretization and an implicit time stepping technique for the case. We show that the regime-switching scheme can revert to the non-switching Black Scholes equation, both in theoretical evidence and numerical simulations.

Lung Volume Reduction in Pulmonary Emphysema from the Radiologist's Perspective.

PubMed

Doellinger, F; Huebner, R H; Kuhnigk, J M; Poellinger, A

2015-08-01

Pulmonary emphysema causes decrease in lung function due to irreversible dilatation of intrapulmonary air spaces, which is linked to high morbidity and mortality. Lung volume reduction (LVR) is an invasive therapeutical option for pulmonary emphysema in order to improve ventilation mechanics. LVR can be carried out by lung resection surgery or different minimally invasive endoscopical procedures. All LVR-options require mandatory preinterventional evaluation to detect hyperinflated dysfunctional lung areas as target structures for treatment. Quantitative computed tomography can determine the volume percentage of emphysematous lung and its topographical distribution based on the lung's radiodensity. Modern techniques allow for lobebased quantification that facilitates treatment planning. Clinical tests still play the most important role in post-interventional therapy monitoring, but CT is crucial in the detection of postoperative complications and foreshadows the method's high potential in sophisticated experimental studies. Within the last ten years, LVR with endobronchial valves has become an extensively researched minimally-invasive treatment option. However, this therapy is considerably complicated by the frequent occurrence of functional interlobar shunts. The presence of "collateral ventilation" has to be ruled out prior to valve implantations, as the presence of these extraanatomical connections between different lobes may jeopardize the success of therapy. Recent experimental studies evaluated the automatic detection of incomplete lobar fissures from CT scans, because they are considered to be a predictor for the existence of shunts. To date, these methods are yet to show acceptable results. Today, surgical and various minimal invasive methods of lung volume reduction are in use. Radiological and nuclear medical examinations are helpful in the evaluation of an appropriate lung area. Imaging can detect periinterventional complications. Reduction of lung volume has not yet been conclusively proven to be effective and is a therapeutical option with little scientific evidence. © Georg Thieme Verlag KG Stuttgart · New York.

Space station systems analysis study. Part 2, Volume 2. [technical report

NASA Technical Reports Server (NTRS)

1977-01-01

Specific system options are defined and identified for a cost effective space station capable of orderly growth with regard to both function and orbit location. Selected program options are analyzed and configuration concepts are developed to meet objectives for the satellite power system, earth servicing, space processing, and supporting activities. Transportation systems are analyzed for both LEO and GEO orbits.

Fuel quality-processing study. Volume 2: Literature survey

NASA Technical Reports Server (NTRS)

Jones, G. E., Jr.; Amero, R.; Murthy, B.; Cutrone, M.

1981-01-01

The validity of initial assumptions about raw materials choices and relevant upgrading processing options was confirmed. The literature survey also served to define the on-site (at the turbine location) options for fuel treatment and exhaust gas treatment. The literature survey also contains a substantial compilation of specification and physical property information about liquid fuel products relevant to industrial gas turbines.

A study of space station needs, attributes, and architectural options, volume 2, technical. Book 2: Mission implementation concepts

NASA Technical Reports Server (NTRS)

1983-01-01

Space station systems characteristics and architecture are described. A manned space station operational analysis is performed to determine crew size, crew task complexity and time tables, and crew equipment to support the definition of systems and subsystems concepts. This analysis is used to select and evaluate the architectural options for development.

Spacelab experiment computer study. Volume 1: Executive summary (presentation)

NASA Technical Reports Server (NTRS)

Lewis, J. L.; Hodges, B. C.; Christy, J. O.

1976-01-01

A quantitative cost for various Spacelab flight hardware configurations is provided along with varied software development options. A cost analysis of Spacelab computer hardware and software is presented. The cost study is discussed based on utilization of a central experiment computer with optional auxillary equipment. Groundrules and assumptions used in deriving the costing methods for all options in the Spacelab experiment study are presented. The groundrules and assumptions, are analysed and the options along with their cost considerations, are discussed. It is concluded that Spacelab program cost for software development and maintenance is independent of experimental hardware and software options, that distributed standard computer concept simplifies software integration without a significant increase in cost, and that decisions on flight computer hardware configurations should not be made until payload selection for a given mission and a detailed analysis of the mission requirements are completed.

Study of the feasibility of utilizing solar, wind, and geothermal energy in Hobbs, New Mexico. Final report. Volume 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, B.J.; Huettner, D.A.; Murry, D.

The objective of this study was to provide an economic analysis of the various solar options for Hobbs, New Mexico. In so doing, an assessment of the current state of the art in solar research was obtained. Cost estimates were provided assuming capacity 100 MW. These options were: Central Receiver, Cylindrical Trough, Parabolic Dish Non-Brayton, Parabolic Dish Brayton, Fixed Mirror Distributed Focus, Dispersed Photovoltaic ERDA Goal, and Dispersed Photovoltaic Present Quote. Three scenarios were used to analyze all of the solar options relative to conventional fossil systems and nuclear alternatives. A total of thirty-two different options were considered. Results andmore » conclusions are presented. (MHR)« less

A parallel coordinates style interface for exploratory volume visualization.

PubMed

Tory, Melanie; Potts, Simeon; Möller, Torsten

2005-01-01

We present a user interface, based on parallel coordinates, that facilitates exploration of volume data. By explicitly representing the visualization parameter space, the interface provides an overview of rendering options and enables users to easily explore different parameters. Rendered images are stored in an integrated history bar that facilitates backtracking to previous visualization options. Initial usability testing showed clear agreement between users and experts of various backgrounds (usability, graphic design, volume visualization, and medical physics) that the proposed user interface is a valuable data exploration tool.

Space station needs, attributes, and architectural options study. Volume 2: Program options, architecture, and technology

NASA Technical Reports Server (NTRS)

1983-01-01

Mission scenarios and space station architectures are discussed. Electrical power subsystems (EPS), environmental control and life support, subsystems (ECLSS), and reaction control subsystem (RCS) architectures are addressed. Thermal control subsystems, (TCS), guidance/navigation and control (GN and C), information management systems IMS), communications and tracking (C and T), and propellant transfer and storage systems architectures are discussed.

76 FR 40978 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-12

... to attract more customer volume to the Exchange in this option class and to allow CBOE market-makers to better compete for order flow. CBOE noted that the SPY option class is unique in the manner in... continue to enable CBOE to compete for order flow in the SPY option class. However, because the SPY option...

Space station needs, attributes and architectural options study. Volume 2: Appendix C

NASA Technical Reports Server (NTRS)

1983-01-01

Planetary science, Earth observation, space physics, astronomy, solar astronomy, life/biological sciences, materials processing, commercial materials processing, commercial communications, and technology development are discussed.

Impact Assessment and Forecasts of Information and Telecommunications Technologies Applied to Education and Training: Volume II--Main Report and Issues Analyses. Analysis for the Orientation of the Work of Sector Actors in the Framework of DELTA.

ERIC Educational Resources Information Center

Commission of the European Communities, Brussels (Belgium).

This report, the second volume in a three volume set, summarizes the results of a study performed by the DELTA (Developing European Learning through Technological Advance) unit in parallel with the projects underway in the research and development Exploratory Action. The report identifies the key issues, associated requirements and options, and…

77 FR 38362 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-27

... Effectiveness of a Proposed Rule Change To Increase the Class Quoting Limit for Options on Facebook June 21... Limit (``CQL'') for options on Facebook. The text of the proposed rule change is available on the... the Exchange recently began electronically trading options on Facebook, trading volume and TPH...

Space station needs, attributes, and architectural options study. Volume 3: Cost and benefits

NASA Technical Reports Server (NTRS)

1983-01-01

Cost and schedule, cost/incremental capability, and schedule impact analyses are presented. Quantifiable benefits, space technology, non-quantifiable benefits, and space commercialization are addressed.

Space Applications of Automation, Robotics and Machine Intelligence Systems (ARAMIS). Volume 1: Executive Summary

NASA Technical Reports Server (NTRS)

Miller, R. H.; Minsky, M. L.; Smith, D. B. S.

1982-01-01

Potential applications of automation, robotics, and machine intelligence systems (ARAMIS) to space activities, and to their related ground support functions are explored. The specific tasks which will be required by future space projects are identified. ARAMIS options which are candidates for those space project tasks and the relative merits of these options are defined and evaluated. Promising applications of ARAMIS and specific areas for further research are identified. The ARAMIS options defined and researched by the study group span the range from fully human to fully machine, including a number of intermediate options (e.g., humans assisted by computers, and various levels of teleoperation). By including this spectrum, the study searches for the optimum mix of humans and machines for space project tasks.

Draft Site Treatment Plan (DSTP), Volumes I and II

DOE Office of Scientific and Technical Information (OSTI.GOV)

D`Amelio, J.

1994-08-30

Site Treatment Plans (STP) are required for facilities at which the DOE generates or stores mixed waste. This Draft Site Treatment Plan (DSTP) the second step in a three-phase process, identifies the currently preferred options for treating mixed waste at the Savannah River Site (SRS) or for developing treatment technologies where technologies do not exist or need modification. The DSTP reflects site-specific preferred options, developed with the state`s input and based on existing available information. To the extent possible, the DSTP identifies specific treatment facilities for treating the mixed waste and proposes schedules. Where the selection of specific treatment facilitiesmore » is not possible, schedules for alternative activities such as waste characterization and technology assessment are provided. All schedule and cost information presented is preliminary and is subject to change. The DSTP is comprised of two volumes: this Compliance Plan Volume and the Background Volume. This Compliance Plan Volume proposes overall schedules with target dates for achieving compliance with the land disposal restrictions (LDR) of RCRA and procedures for converting the target dates into milestones to be enforced under the Order. The more detailed discussion of the options contained in the Background Volume is provided for informational purposes only.« less

Space Applications of Automation, Robotics and Machine Intelligence Systems (ARAMIS). Volume 4: Supplement, Appendix 4.3: Candidate ARAMIS Capabilities

NASA Technical Reports Server (NTRS)

Miller, R. H.; Minsky, M. L.; Smith, D. B. S.

1982-01-01

Potential applications of automation, robotics, and machine intelligence systems (ARAMIS) to space activities, and to their related ground support functions, in the years 1985-2000, so that NASA may make informed decisions on which aspects of ARAMIS to develop. The study first identifies the specific tasks which will be required by future space projects. It then defines ARAMIS options which are candidates for those space project tasks, and evaluates the relative merits of these options. Finally, the study identifies promising applications of ARAMIS, and recommends specific areas for further research. The ARAMIS options defined and researched by the study group span the range from fully human to fully machine, including a number of intermediate options (e.g., humans assisted by computers, and various levels of teleoperation). By including this spectrum, the study searches for the optimum mix of humans and machines for space project tasks.

District heating and cooling systems for communities through power plant retrofit distribution network, Phase 2. Final report, 1 March 1980-31 January 1984. Volume II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1984-01-31

This volume begins with an Introduction summarizing the history, methodology and scope of the study, the project team members and the private and public groups consulted in the course of the study. The Load and Service Area Assessment follows, including: a compilation and analysis of existing statistical thermal load data from census data, industrial directories, PSE and G records and other sources; an analysis of responses to a detailed, 4-page thermal load questionnaire; data on public buildings and fuel and energy use provided by the New Jersey Dept. of Energy; and results of other customer surveys conducted by PSE andmore » G. A discussion of institutional questions follows. The general topic of rates is then discussed, including a draft hypothetical Tariff for Thermal Services. Financial considerations are discussed including a report identifying alternative ownership/financing options for district heating systems and the tax implications of these options. Four of these options were then selected by PSE and G and a financial (cash-flow) analysis done (by the PSE and G System Planning Dept.) in comparison with a conventional heating alternative. Year-by-year cost of heat ($/10/sup 6/ Btu) was calculated and tabulated, and the various options compared.« less

Individual differences in decision making by foraging hummingbirds.

PubMed

Morgan, Kate V; Hurly, T Andrew; Healy, Susan D

2014-11-01

For both humans and animals preference for one option over others can be influenced by the context in which the options occur. In animals, changes in preference could be due to comparative decision-making or to changes in the energy state of the animal when making decisions. We investigated which of these possibilities better explained the response of wild hummingbirds to the addition of a decoy option to a set of two options by presenting Rufous hummingbirds (Selasphorus rufus) with a foraging experiment with two treatments. In each treatment the birds were presented with a binary choice between two options and a trinary choice with three options. In treatment one the binary choice was between a volume option and a concentration option, whereas in treatment two the same volume option was presented alongside an alternative concentration option. In the trinary choice, birds were presented with the same options as in the binary choice plus one of two inferior options. Birds changed their preferences when a poorer option was added to the choice set: birds increased their preference for the same option when in the presence of either decoy. Which option differed across individuals and the changes in preference were not readily explained by either energy maximisation or the decoy effect. The consistency in response within individuals, however, would suggest that the individual itself brings an extra dimension to context-dependent decision-making. This article is part of a Special Issue entitled: Cognition in the wild. Copyright © 2014 Elsevier B.V. All rights reserved.

Geostationary Operational Environmental Satellite (GOES-N report). Volume 1: Technical

NASA Technical Reports Server (NTRS)

1991-01-01

The GOES-N study consisted of five distinct tasks including: determining replication costs of GOES I-M and GOES-7 in the GOES-N time frame; defining and evaluating modifications to GOES I-M to improve efficiency or reduce costs; and defining evolutionary changes to the GOES I-M design to satisfy National Weather Service (NWS) 1983 and NOAA 1989 requirements. The categorization and disposition of NOAA requirements is reported in volume 1 section 4. Results of the GOES I-M efficiency/cost improvement modifications study are described in Section 7.1. The system concept options 1, 2, and 3 that generally represent the results of the Task 2, 3A, and 3B studies are summarized in Section 7.2. Another result of the GOES-N study, the determination of which NWS 1983 and NOAA 1989 requirements can be met with the three options, is contained in volume 1 section 7. Conclusions and recommendations are covered in volume 1 section 8. Imager, sounder, control system, space environment monitor, search and rescue, weather facsimile, data collection system, and products/process/communications recommendations were extracted from sections 9, 10, and 11. Section 8 also contains conclusions pertaining to programmatic operational satellite issues (prerequisite development strategies, the direct procurement of instruments by the government, protoflight mission, etc.). Sections 9, 10, and 11 address instrument, control system, image/navigation/registration, and other system design considerations and surveys. These sections are supported by the appendices in volume 2.

Geostationary Operational Environmental Satellite (GOES-N report). Volume 1: Technical

NASA Astrophysics Data System (ADS)

1991-12-01

The GOES-N study consisted of five distinct tasks including: determining replication costs of GOES I-M and GOES-7 in the GOES-N time frame; defining and evaluating modifications to GOES I-M to improve efficiency or reduce costs; and defining evolutionary changes to the GOES I-M design to satisfy National Weather Service (NWS) 1983 and NOAA 1989 requirements. The categorization and disposition of NOAA requirements is reported in volume 1 section 4. Results of the GOES I-M efficiency/cost improvement modifications study are described in Section 7.1. The system concept options 1, 2, and 3 that generally represent the results of the Task 2, 3A, and 3B studies are summarized in Section 7.2. Another result of the GOES-N study, the determination of which NWS 1983 and NOAA 1989 requirements can be met with the three options, is contained in volume 1 section 7. Conclusions and recommendations are covered in volume 1 section 8. Imager, sounder, control system, space environment monitor, search and rescue, weather facsimile, data collection system, and products/process/communications recommendations were extracted from sections 9, 10, and 11. Section 8 also contains conclusions pertaining to programmatic operational satellite issues (prerequisite development strategies, the direct procurement of instruments by the government, protoflight mission, etc.). Sections 9, 10, and 11 address instrument, control system, image/navigation/registration, and other system design considerations and surveys. These sections are supported by the appendices in volume 2.

Savannah River Site Approved Site Treatment Plan, 2001 Annual Update (Volumes I and II)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawrence, B.

2001-04-30

The Compliance Plan Volume (Volume I) identifies project activity scheduled milestones for achieving compliance with Land Disposal Restrictions. Information regarding the technical evaluation of treatment options for SRS mixed wastes is contained in the Background Volume (Volume II) and is provided for information.

Technical draft study report for TOPEX satellite options study, volume 1

NASA Technical Reports Server (NTRS)

1981-01-01

The use of two spacecraft for adaptation to the TOPEX mission, namely the P80-1 and the GPS phase 2 are considered. The mission involved three mission options, each option varying in payload definition, payload weight, orbital altitude and payload power requirements. The P80-1 spacecraft is an Air Force Space Test Program satellite which carries a number of payloads to an orbital altitude of 400 n.mi. at a minimum inclination of 72.5 deg, and which has an orbital life capability of three years. The GPS phase 2 spacecraft is the operational satellite for the Global Positioning NAVSTAR navigation constellation provided for all service (and commercial) use.

76 FR 63976 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-14

... proposed change is intended to attract more customer volume to the Exchange in the SPY option class and to allow CBOE market-makers to better compete for order flow. CBOE noted that the SPY option class is... class. CBOE believes that the current demographics of electronic SPY option order flow is more driven by...

76 FR 20411 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-12

... intended to attract more customer volume to the Exchange in this option class and to allow CBOE market-makers to better compete for order flow. CBOE noted that the SPY option class is unique in the manner in... proposed and will continue to enable CBOE to compete for order flow in the SPY option class. However...

Freight Transportation Energy Use : Volume 4. Analysis of Selected Energy Conservation Options.

DOT National Transportation Integrated Search

1978-07-01

The TSC Freight Energy Model is applied to a preliminary analysis of two energy conservation options: (1) increased use of Run-Through TOFC rail service; and (2) use of double 40-foot trailers on all divided highways. These options are examined prima...

Comparing Trash Disposal and Reuse Options for Deep Space Gateway and Mars Missions

NASA Technical Reports Server (NTRS)

Ewert, Michael; Broyan, James; Goodliff, Kandyce; Clowdsley, Martha; Singleterry, Robert

2017-01-01

Taking out the trash at NASA's newly proposed Deep Space Gateway (DSG) will not be a trivial task. While not the most important aspect of planning this cislunar outpost, there are several options that should be carefully considered since they may affect the crew as well as mission mass and volume. This study extends an earlier one, which focused on waste disposal options for a Mars Transit Vehicle. In that study, gasifying and venting trash along the way was found to noticeably reduce propellant needs and launch mass, whereas keeping processed trash on board in the form of radiation shielding tiles would significantly lower the crew's radiation dose during a solar particle event. Another favorable strategy was packing trash in a used logistics module for disposal. Since the DSG does not need much propulsion to maintain its orbit and Orion will be present with its own radiation storm shelter at the Gateway, the driving factors of the waste disposal trade study are different than for the Mars mission. Besides reviewing the propulsion and radiation shielding factors, potential drivers such as mass, power, volume, crew time, and human factors (e.g. smell) were studied. Disposal options for DSG include jettison of a used logistics module containing waste after every human stay, jettison of the same logistics module after several missions once it is full, regular disposal of trash via an airlock, or gasifying waste products for easier disposal or reuse. Conversely, a heat melt compactor device could be used to remove water and stabilize trash into tiles which could be more compactly stored on board and used as radiation shielding. Equivalent system mass analysis is used to tally the benefits and costs (mass, volume, power, crew time) of each case on an equivalent mass basis. Other more subjective factors are also discussed. Recommendations are made for DSG and Mars mission waste disposal.

Human Transportation System (HTS) study, volume 2

NASA Technical Reports Server (NTRS)

Lance, N.; Geyer, M. S.; Gaunce, M. T.

1993-01-01

This report summarizes work completed under the Human Transportation System Study. This study was conducted by the New Initiatives Office at JSC with the technical support of Boeing, General Dynamics, Lockheed, McDonnell-Douglas, Martin Marietta, and Rockwell. The study was designed to generate information on determining the appropriate path to follow for new system development to meet the Nation's space transportation needs. The study evaluates 18 transportation architecture options using a parametric set of mission requirements. These options include use of current systems (e.g., Shuttle, Titan, etc. ) as well as proposed systems (e.g., PLS, Single-Stage-to-Orbit, etc.) to assess the impact of various considerations, such as the cost of alternate access, or the benefit of separating people and cargo. The architecture options are compared to each other with six measurable evaluation criteria or attributes. They are: funding profile, human safety, probability of mission success, architecture cost risk, launch schedule confidence, and environmental impact. Values for these attributes are presented for the architecture options, with pertinent conclusions and recommendations.

Human Transportation System (HTS) study, volume 1

NASA Technical Reports Server (NTRS)

Lance, N.; Geyer, M. S.; Gaunce, M. T.

1993-01-01

Work completed under the Human Transportation System Study is summarized. This study was conducted by the New Initiatives Office at JSC with the technical support of Boeing, General Dynamics, Lockheed, McDonnell-Douglas, Martin Marietta, and Rockwell. The study was designed to generate information on determining the appropriate path to follow for new system development to meet the Nation's space transportation needs. The study evaluates 18 transportation architecture options using a parametric set of mission requirements. These options include use of current systems as well as proposed systems to assess the impact of various considerations, such as the cost of alternate access, or the benefit of separating people and cargo. The architecture options are compared to each other with six measurable evaluation criteria or attributes. They are the following: funding profile, human safety, probability of mission success, architecture cost risk, launch schedule confidence, and environmental impact. Values for these attributes are presented for the architecture options, with pertinent conclusions and recommendations.

76 FR 44969 - Self-Regulatory Organizations; NYSE Arca Inc.; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-27

...[supreg] exchange-traded fund (``SPY ETF''),\\4\\ which list and trade under the option symbol SPY, and to.... The SPDR S&P 500 ETF represents ownership in the SPDR S&P 500 Trust, a unit investment trust that... volume of SPY options). \\7\\ QQQ options were formerly known as options on the Nasdaq-100 Tracking Stock...

Saugus River and Tributaries Flood Damage Reduction Study: Lynn, Malden, Revere and Saugus, Massachusetts. Volume 7. Appendix J. Feasibility Study and EIS/EIR Comments and Responses. Section C. Final Report Review,

DTIC Science & Technology

1990-04-01

There are significant differences between the social , economic and environ- mental impacts associated with Option 1, as described in the report when...Engineers, the project is authorized Sink# Pinka by the U.S. Congress. and after the completion of plans and specifications, Stone Memoria zoos which...project. The individuals and businesses who will derive cV act social and economic benefits from this option are not being required to contribute to

Food System Trade Study for a Near-Term Mars Mission

NASA Technical Reports Server (NTRS)

Levri, Julie; Luna, Bernadette (Technical Monitor)

2000-01-01

This paper evaluates several food system options for a near-term Mars mission, based on plans for the 120-day BIO-Plex test. Food systems considered in the study are based on the International Space Station (ISS) Assembly Phase and Assembly Complete food systems. The four systems considered are: 1) ISS assembly phase food system (US portion) with individual packaging without salad production; 2) ISS assembly phase food system (US portion) with individual packaging, with salad production; 3) ISS assembly phase food system (US portion) with bulk packaging, with salad production; 4) ISS assembly complete food system (US portion) with bulk packaging with salad and refrigeration/freezing. The food system options are assessed using equivalent system mass (ESM), which evaluates each option based upon the mass, volume, power, cooling and crewtime requirements that are associated with each food system option. However, since ESM is unable to elucidate the differences in psychological benefits between the food systems, a qualitative evaluation of each option is also presented.

IMP: Interactive mass properties program. Volume 1: Program description

NASA Technical Reports Server (NTRS)

Stewart, W. A.

1976-01-01

A method of computing a weights and center of gravity analysis of a flight vehicle using interactive graphical capabilities of the Adage 340 computer is described. The equations used to calculate area, volume, and mass properties are based on elemental surface characteristics. The input/output methods employ the graphic support of the Adage computer. Several interactive program options are available for analyzing the mass properties of a vehicle. These options are explained.

Impact Assessment and Forecasts of Information and Telecommunications Technologies Applied to Education and Training. R&D in Information and Communication Based Learning Technology. Analysis of Key Issues for the Orientation of the Work of Sector Actors in the Framework of DELTA. Volume I--Executive Summary.

ERIC Educational Resources Information Center

Commission of the European Communities, Brussels (Belgium).

This report, the first volume in a three volume set, summarizes the results of a study performed by the DELTA (Developing European Learning through Technological Advance) Unit in parallel with the projects underway in the research and development Exploratory Action. The report identifies the key issues, associated requirements and options, and…

Space applications of Automation, Robotics and Machine Intelligence Systems (ARAMIS). Volume 4: Application of ARAMIS capabilities to space project functional elements

NASA Technical Reports Server (NTRS)

Miller, R. H.; Minsky, M. L.; Smith, D. B. S.

1982-01-01

Applications of automation, robotics, and machine intelligence systems (ARAMIS) to space activities and their related ground support functions are studied, so that informed decisions can be made on which aspects of ARAMIS to develop. The specific tasks which will be required by future space project tasks are identified and the relative merits of these options are evaluated. The ARAMIS options defined and researched span the range from fully human to fully machine, including a number of intermediate options (e.g., humans assisted by computers, and various levels of teleoperation). By including this spectrum, the study searches for the optimum mix of humans and machines for space project tasks.

Analysis of space systems study for the space disposal of nuclear waste study report. Volume 2: Technical report

NASA Technical Reports Server (NTRS)

1981-01-01

Reasonable space systems concepts were systematically identified and defined and a total system was evaluated for the space disposal of nuclear wastes. Areas studied include space destinations, space transportation options, launch site options payload protection approaches, and payload rescue techniques. Systems level cost and performance trades defined four alternative space systems which deliver payloads to the selected 0.85 AU heliocentric orbit destination at least as economically as the reference system without requiring removal of the protective radiation shield container. No concepts significantly less costly than the reference concept were identified.

Cone beam volume tomography: an imaging option for diagnosis of complex mandibular third molar anatomical relationships.

PubMed

Danforth, Robert A; Peck, Jerry; Hall, Paul

2003-11-01

Complex impacted third molars present potential treatment complications and possible patient morbidity. Objectives of diagnostic imaging are to facilitate diagnosis, decision making, and enhance treatment outcomes. As cases become more complex, advanced multiplane imaging methods allowing for a 3-D view are more likely to meet these objectives than traditional 2-D radiography. Until recently, advanced imaging options were somewhat limited to standard film tomography or medical CT, but development of cone beam volume tomography (CBVT) multiplane 3-D imaging systems specifically for dental use now provides an alternative imaging option. Two cases were utilized to compare the role of CBVT to these other imaging options and to illustrate how multiplane visualization can assist the pretreatment evaluation and decision-making process for complex impacted mandibular third molar cases.

Benefit-Cost Analysis of Integrated Paratransit Systems : Volume 2. Introduction and Framework for Analysis.

DOT National Transportation Integrated Search

1979-09-01

The study represents the first systematic attempt to estimate the potential impacts of a wide range of IP options in different settings. The output of this study should provide local decision-makers with a better understanding of the varied impacts a...

76 FR 41839 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-15

... Effectiveness of Proposed Rule Change Relating to PAR Official Fees in Volatility Index Options July 7, 2011... threshold tiers for the assessment of PAR Official Fees in Volatility Index Options classes based on the..., 2011 to establish volume threshold tiers for the assessment of PAR Official Fees in Volatility Index...

Excellence at Work. Policy Option Papers for the National Governors' Association.

ERIC Educational Resources Information Center

Ganzglass, Evelyn, Ed.

This volume contains an introduction and four policy option papers that explore key issues affecting the economy and state options to address the issues within the context of the U.S. workplace. "Introduction" (David Bedford, Evelyn Ganzglass) discusses the issues identified in the first phase of the governors' initiative on Excellence at Work and…

Space station needs, attributes and architectural options study. Volume 7-1: Data book. Science and applications missions

NASA Technical Reports Server (NTRS)

1983-01-01

User requirements for space station use are presented for the following areas: space environments, astrophysics, Earth observations, and life science. Also included are a summary of study tasks and final reports, a topical cross reference, key team members, and acronyms and abbreviations.

Computer Aided Design of Polyhedron Solids to Model Air in Com-Geom Descriptions

DTIC Science & Technology

1983-08-01

34The GIFT Code User Manual, Volume I, Introduction and Input Requirements," BRL Report No. 1802, July 1975 (Unclassified). (AD B0060Z7LK 2G...Kuehl, L. Bain and M. Reisinger, "The GIFT Code User Manual, Volume II, The Output Options," BRL Report ARBRL-TR-02189, September 1979...is generated from the GIFT code under op- tion XSECT. This option produces plot files which define cross- sectional views of the COM-GEOM

78 FR 7467 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-01

... Effectiveness of a Proposed Rule Change Relating to Minimum Volume Orders January 28, 2013. Pursuant to Section... to codify the ``Minimum Volume Order.'' The text of the proposed rule change is provided below... Circular. (a)-(v) No changes. (w) Minimum Volume Order. A minimum volume order is an order represented in...

Space station crew safety alternatives study. Volume 3: Safety impact of human factors

NASA Technical Reports Server (NTRS)

Rockoff, L. A.; Raasch, R. F.; Peercy, R. L., Jr.

1985-01-01

The first 15 years of accumulated space station concepts for Initial Operational Capability (IOC) during the early 1990's was considered. Twenty-five threats to the space station are identified and selected threats addressed as impacting safety criteria, escape and rescue, and human factors safety concerns. Of the 25 threats identified, eight are discussed including strategy options for threat control: fire, biological or toxic contamination, injury/illness, explosion, loss of pressurization, radiation, meteoroid penetration and debris. Of particular interest here is volume three (of five volumes) pertaining to the safety impact of human factors.

Space station needs, attributes and architectural options. Volume 1: Executive summary NASA

NASA Technical Reports Server (NTRS)

1983-01-01

The uses alignment plan was implemented. The existing data bank was used to define a large number of station requirements. Ten to 20 valid mission scenarios were developed. Architectural options as they are influenced by communications operations, subsystem evolvability, and required technology growth are defined. Costing of evolutionary concepts, alternative approaches, and options, was based on minimum design details.

BIANCA (Brain Intensity AbNormality Classification Algorithm): A new tool for automated segmentation of white matter hyperintensities.

PubMed

Griffanti, Ludovica; Zamboni, Giovanna; Khan, Aamira; Li, Linxin; Bonifacio, Guendalina; Sundaresan, Vaanathi; Schulz, Ursula G; Kuker, Wilhelm; Battaglini, Marco; Rothwell, Peter M; Jenkinson, Mark

2016-11-01

Reliable quantification of white matter hyperintensities of presumed vascular origin (WMHs) is increasingly needed, given the presence of these MRI findings in patients with several neurological and vascular disorders, as well as in elderly healthy subjects. We present BIANCA (Brain Intensity AbNormality Classification Algorithm), a fully automated, supervised method for WMH detection, based on the k-nearest neighbour (k-NN) algorithm. Relative to previous k-NN based segmentation methods, BIANCA offers different options for weighting the spatial information, local spatial intensity averaging, and different options for the choice of the number and location of the training points. BIANCA is multimodal and highly flexible so that the user can adapt the tool to their protocol and specific needs. We optimised and validated BIANCA on two datasets with different MRI protocols and patient populations (a "predominantly neurodegenerative" and a "predominantly vascular" cohort). BIANCA was first optimised on a subset of images for each dataset in terms of overlap and volumetric agreement with a manually segmented WMH mask. The correlation between the volumes extracted with BIANCA (using the optimised set of options), the volumes extracted from the manual masks and visual ratings showed that BIANCA is a valid alternative to manual segmentation. The optimised set of options was then applied to the whole cohorts and the resulting WMH volume estimates showed good correlations with visual ratings and with age. Finally, we performed a reproducibility test, to evaluate the robustness of BIANCA, and compared BIANCA performance against existing methods. Our findings suggest that BIANCA, which will be freely available as part of the FSL package, is a reliable method for automated WMH segmentation in large cross-sectional cohort studies. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. I. Collection of Virus Samples

PubMed Central

Fout, G. Shay; Cashdollar, Jennifer L.; Varughese, Eunice A.; Parshionikar, Sandhya U.; Grimm, Ann C.

2015-01-01

EPA Method 1615 was developed with a goal of providing a standard method for measuring enteroviruses and noroviruses in environmental and drinking waters. The standardized sampling component of the method concentrates viruses that may be present in water by passage of a minimum specified volume of water through an electropositive cartridge filter. The minimum specified volumes for surface and finished/ground water are 300 L and 1,500 L, respectively. A major method limitation is the tendency for the filters to clog before meeting the sample volume requirement. Studies using two different, but equivalent, cartridge filter options showed that filter clogging was a problem with 10% of the samples with one of the filter types compared to 6% with the other filter type. Clogging tends to increase with turbidity, but cannot be predicted based on turbidity measurements only. From a cost standpoint one of the filter options is preferable over the other, but the water quality and experience with the water system to be sampled should be taken into consideration in making filter selections. PMID:25867928

Study of the Employment Status of Block Program Graduates. Teacher Education Forum; Volume 4, Number 7.

ERIC Educational Resources Information Center

Buffie, Edward G.

The Block Program is one of five major options at Indiana University, Bloomington, for students preparing to become elementary teachers. The project emphasizes team approach to instruction; flexibility of program; carefully articulated work with respect to preparation in language arts, mathematics, science, and social studies; carefully…

Space Tug avionics definition study. Volume 4: Supporting trade studies and analyses

NASA Technical Reports Server (NTRS)

1975-01-01

Analyses and trade studies were performed for the evaluation of the most desirable solutions to space tug subsystem requirements. These were accomplished at system, subsystem, and at component levels. The criteria, the candidate options evaluated, the selection process, and the recommended solutions that have been integrated together in the configuration descriptions are reported.

Spacelab Level 4 Programmatic Implementation Assessment Study. Volume 2: Ground Processing requirements

NASA Technical Reports Server (NTRS)

1978-01-01

Alternate ground processing options are summarized, including installation and test requirements for payloads, space processing, combined astronomy, and life sciences. The level 4 integration resource requirements are also reviewed for: personnel, temporary relocation, transportation, ground support equipment, and Spacelab flight hardware.

Shades of Green: Flood control study focused on Duluth, Minnesota

EPA Science Inventory

In the aftermath of the economically and environmentally painful flood of 2012, the city of Duluth and the CSC examined ecologically based options to reduce runoff velocities and flood volume in the watershed with assistance and input of Minnesota Duluth's Natural Resources Resea...

Can Roadway Design be used to Mitigate Air Quality Impacts from Traffic?

EPA Science Inventory

Recent studies have confirmed the increased risks to human health for populations near roadways with large traffic volumes. This paper summarizes methods in which these impacts may be mitigated by infrastructure design options such as roadway configuration and roadside structures...

Solar power satellite system definition study. Volume 5, phase 1: Executive summary

NASA Technical Reports Server (NTRS)

1979-01-01

An analysis of the solar power satellite system is presented. Performance, cost, and operational characteristics are assessed. The photovoltaic system is described and investigated. Alternative construction concepts are discussed. The structural bay configuration is presented along with the antenna structure options.

Estimating near-road pollutant dispersion: a model inter-comparison

EPA Science Inventory

A model inter-comparison study to assess the abilities of steady-state Gaussian dispersion models to capture near-road pollutant dispersion has been carried out with four models (AERMOD, run with both the area-source and volume-source options to represent roadways, CALINE, versio...

Space station needs, attributes and architectural options study. Volume 2: Mission definition

NASA Technical Reports Server (NTRS)

1983-01-01

The space applications and science programs appropriate to the era beyond 1990, those user missions which can utilize the Space Station to an advantage, and user mission concepts so that requirements, which will drive the Space Stations (SS) design are addressed.

An Analysis of Fuel Cell Options for an All-electric Unmanned Aerial Vehicle

NASA Technical Reports Server (NTRS)

Kohout, Lisa L.; Schmitz, Paul C.

2007-01-01

A study was conducted to assess the performance characteristics of both PEM and SOFC-based fuel cell systems for an all-electric high altitude, long endurance Unmanned Aerial Vehicle (UAV). Primary and hybrid systems were considered. Fuel options include methane, hydrogen, and jet fuel. Excel-based models were used to calculate component mass as a function of power level and mission duration. Total system mass and stored volume as a function of mission duration for an aircraft operating at 65 kft altitude were determined and compared.

Reducing the Deficit: Spending and Revenue Options. A Report to the Senate and House Committees on the Budget - Part II

DTIC Science & Technology

1989-02-01

tax law usually take effect at the beginning of a calendar year. The excise and energy tax options, however, are assumed to take effect on October 1...this volume would take effect on October 1, 1989, the revenue options generally have an effective date of January 1, 1990, because changes in income

Balancing Work and Family through Flexible Work Options. Monograph. Volume 9, Number 1.

ERIC Educational Resources Information Center

Sachs, Sharon

More than 58 percent of all women working in the U.S. labor force, many of them sole supports of their families, and 67 percent of women with children under age 18 are working. Therefore, more flexible work options are being made to allow a balance of work and family. Increasingly available options include work at home, compressed workweeks,…

Direct lymphangiography as treatment option of lymphatic leakage: indications, outcomes and role in patient's management.

PubMed

Gruber-Rouh, Tatjana; Naguib, Nagy N N; Lehnert, Thomas; Harth, Marc; Thalhammer, Axel; Beeres, Martin; Tsaur, Igor; Hammersting, Renate; Wichmann, Julian L; Vogl, Thomas J; Jacobi, Volkmar

2014-12-01

To evaluate the effectiveness of lymphography as a minimally invasive treatment option of lymphatic leakage in terms of local control and to investigate which parameters influence the success rate. This retrospective study protocol was approved by the ethic committee. Patient history, imaging data, therapeutic options and follow-up were recorded and retrospectively analyzed. Between June 1998 and February 2013, 71 patients (m:w = 42:29, mean age, 52.4; range 42–75 years) with lymphatic leakage in form of lymphatic fistulas (n = 37), lymphocele (n = 11), chylothorax (n = 13) and chylous ascites (n = 10)underwent lymphography. Sixty-four patients (90.1%) underwent successful lymphography while lymphography failed in 7 cases. Therapeutic success was evaluated and correlated to the volume of lymphatic leakage and to the volume of the applied iodized oil. Signs of leakage or contrast extravasation were directly detected in 64 patients. Of 64 patients, 45 patients (70.3%) were treated and cured after lymphography. Based on the lymphography findings, 19 patients (29.7%) underwent surgical intervention with a completely occlusion of lymphatic leakage. The lymphatic leak could be completely occluded in 96.8% of patients when the lymphatic drainage volume was less than 200 mL/day (n = 33). Even when lymphatic drainage was higher than 200 mL/day (n = 31),therapeutic lymphography was still successful in 58.1% of the patients. Lymphography is an effective, minimally invasive method in the detection and treatment of lymphatic leakage. The volume of lymphatic drainage per day is a significant predictor of the therapeutic success rate. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Space station systems analysis study. Part 2, volume 3: Appendixes, Book 2: Supporting data (7 through 18)

NASA Technical Reports Server (NTRS)

1977-01-01

Topics discussed include: (1) design considerations for a MARS sample return laboratory module for space station investigations; (2) crew productivity as a function of work shift arrangement; (3) preliminary analysis of the local logistics problem on the space construction base; (4) mission hardware construction operational flows and timelines; (5) orbit transfer vehicle concept definition; (6) summary of results and findings of space processing working review; (7) crew and habitability subsystem (option L); (8) habitability subsystem considerations for shuttle tended option L; (9) orbiter utilization in manned sortie missions; (10) considerations in definition of space construction base standard module configuration (option L); (11) guidance, control, and navigation subsystems; and (12) system and design tradeoffs.

An Evaluation of Public Preferences for Superfund Site Cleanup, Volume 1: A Preliminary Assessment (1995)

EPA Pesticide Factsheets

The purpose of the project is to develop a methodology for determining the cleanup options for National Priority List (NPL) sites governed under Superfund legislation that are acceptable to the public. A survey instrument was developed for the study.

Orbital service module systems analysis study documentation. Volume 2: Technical report

NASA Technical Reports Server (NTRS)

1978-01-01

Near term, cost effective concepts were defined to augment the power and duration capability offered to shuttle payload users. Feasible concept options that could evolve to provide free-flying power and other services to users in the 1984 time frame were also examined.

Airport offsite passenger service facilities : an option for improving landside access. Volume II, Access characteristics and travel demand.

DOT National Transportation Integrated Search

2009-01-01

Offsite airport facilities provide ground transportation, baggage and passenger check in, and other transportation services to departing air passengers from a remote location. The purpose of this study was to develop models to determine the airports ...

Estimates of low-level waste volumes and classifications at 2-Unit 1100 MWe reference plants for decommissioning scenarios

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hauf, M.J.; Vance, J.N.; James, D.

1991-01-01

A number of nuclear utilities and industry organizations in the United States have evaluated the requirements for reactor decommissioning. These broad scope studies have addressed the major issues of technology, methodology, safety and costs of decommissioning and have produced substantial volumes of data to describe, in detail, the issues and impacts which result. The objective of this paper to provide CECo a reasonable basis for discussion low-level waste burial volumes for the most likely decommissioning options and to show how various decontamination and VR technologies can be applied to provide additional reduction of the volumes required to be buried atmore » low-level waste burial grounds.« less

Space Station Systems Technology Study. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1984-01-01

The four study areas addressed are: (1) attitude control, (2) data management, (3) long-life thermal management, and (4) automated housekeeping integration. The design concepts in each area were refined. The cost benefits, schedules, and life cycle costs for the options were evaluated. Technology advancement plans were prepared for each of the selected items, and documentation was prepared.

Space station needs, attributes and architectural options study. Volume 2: Mission analysis

NASA Technical Reports Server (NTRS)

1983-01-01

Space environment studies, astrophysics, Earth environment, life sciences, and material sciences are discussed. Commercial communication, materials processing, and Earth observation missions are addressed. Technology development, space operations, scenarios of operational capability, mission requirements, and benefits analysis results for space-produced gallium arsenide crystals, direct broadcasting satellite systems, and a high inclination space station are covered.

Science Education in Canadian Schools. Volume I. Introduction and Curriculum Analyses. Background Study 52.

ERIC Educational Resources Information Center

Orpwood, Graham W. F.; Souque, Jean-Pascal

A major study of Canadian science education was undertaken in 1980 to establish a documented basis for describing the present purposes and general characteristics of science teaching in Canadian schools, to provide a historical analysis of science education in Canada, and to stimulate active deliberation concerning future options for science…

Space station systems analysis study. Part 3: Documentation. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1977-01-01

The space stations systems analysis study is summarized. A cost efffective system concept capable of meeting a broad spectrum of mission requirements was developed. Candidate objectives were reviewed and implementation requirements were defined. Program options for both low earth and geosynchronous orbits were examined. Space construction concepts were analyzed and defined in detail.

Entrepreneurship Education. OPTIONS. Expanding Educational Services for Adults.

ERIC Educational Resources Information Center

Belcher, James O.; Warmbrod, Catharine P.

This monograph is part of OPTIONS, a packaged set of materials developed to provide postsecondary administrators, program planners, curriculum developers, counselors, and instructors with up-to-date, reliable information. This volume and two other monographs are intended to enable counselors and instructors to establish and conduct special…

Reusing remediated CCA-treated wood

Treesearch

Carol A. Clausen

2003-01-01

Options for recycling and reusing chromated-copper-arsenate- (CCA) treated material include dimensional lumber and round wood size reduction, composites, and remediation. Size reduction by remilling, shaving, or resawing CCA-treated wood reduces the volume of landfilled waste material and provides many options for reusing used treated wood. Manufacturing composite...

Soils Investigation for Infiltration-based Green Infrastructure for Sewershed Management (Omaha NE)

EPA Science Inventory

EPA Report Abstract: Infiltration-based green infrastructure and related retrofits for sewershed-level rainfall and stormwater volume capture (e.g., rain gardens, cisterns, etc.) are increasingly being recognized as management options to reduce stormwater volume contribution into...

Rethinking Worklife Options for Older Persons.

ERIC Educational Resources Information Center

Habib, Jack, Ed.; Nusberg, Charlotte, Ed.

This volume contains 19 papers that were presented at a conference addressing critical issues related to employment options for older persons. They are arranged in four sections that cover early retirement policies and their implications; older workers of Asia and the Pacific; the impact of technological change on the employment prospects of older…

Space transfer concepts and analysis for exploration missions. Implementation plan and element description document (draft final). Volume 4: Solar electric propulsion vehicle

NASA Technical Reports Server (NTRS)

1991-01-01

This document presents the solar electric propulsion (SEP) concept design developed as part of the Space Transfer Concepts and Analysis for Exploration Missions (STCAEM) study. The evolution of the SEP concept is described along with the requirements, guidelines and assumptions for the design. Operating modes and options are defined and a systems description of the vehicle is presented. Artificial gravity configuration options and space and ground support systems are discussed. Finally, an implementation plan is presented which addresses technology needs, schedules, facilities, and costs.

NATO Guide for Judgment-Based Operational Analysis in Defence Decision Making (Guide OTAN pour l’analyse operationnelle basee sur le jugement dans la prise de decision de defense). Client-Oriented Volume

DTIC Science & Technology

2012-06-01

disputed thus leading to informed debate about the actions to take. The advice will lead to an informed debate about the pros and cons of...his preferred courses of action, compare pros and cons . Figure 4 illustrates how each phase may include tasks (and methods) that are typical of...options. Output: A compilation of the pros and cons of the three options. An example of presenting the data for this generic acquisition study is

Space transfer concepts and analysis for exploration missions. Implementation plan and element description document (draft final). Volume 2: Cryo/aerobrake vehicle

NASA Technical Reports Server (NTRS)

1991-01-01

The cryogenic/aerobrake (CAB) and the cryogenic all-propulsive (CAP) concept designs developed in support of the Space Transfer Concepts and Analysis for Exploration Missions (STCAEM) study are presented. The evolution of the CAB and CAP concepts is described along with the requirements, guidelines and assumptions for the designs. Operating modes and options are defined and systems descriptions of the vehicles are presented. Artificial gravity configuration options and space and ground support systems are discussed. Finally, an implementation plan is presented which addresses technology needs, schedules, facilities, and costs.

Space transfer concepts and analysis for exploration missions. Implementation plan and element description document (draft final). Volume 5: Nuclear electric propulsion vehicle

NASA Technical Reports Server (NTRS)

1991-01-01

The nuclear electric propulsion (NEP) concept design developed in support of the Space Transfer Concepts and Analysis for Exploration Missions (STCAEM) study is presented. The evolution of the NEP concept is described along with the requirements, guidelines, and assumptions for the design. Operating modes and options are defined and a systems description of the vehicle is presented. Artificial gravity configuration options and space and ground support systems are discussed. Finally, an implementation plan is presented which addresses technology needs, schedules, facilities and costs.

Space transfer concepts and analysis for exploration missions. Implementation plan and element description document (draft final). Volume 3: Nuclear thermal rocket vehicle

NASA Technical Reports Server (NTRS)

1991-01-01

This document presents the nuclear thermal rocket (NTR) concept design developed in support of the Space Transfer Concepts and Analysis for Exploration Missions (STCAEM) study. The evolution of the NTR concept is described along with the requirements, guidelines and assumptions for the design. Operating modes and options are defined and a systems description of the vehicle is presented. Artificial gravity configuration options and space and ground support systems are discussed. Finally, an implementation plan is presented which addresses technology needs, schedules, facilities and costs.

Mission Information: Worksite Interview, Shadow Community Workers, Work Experience Program. CHOICE (Challenging Options in Career Education).

ERIC Educational Resources Information Center

Gans, Connie; And Others

The work-study guide is the third volume in the advanced level of a career education curriculum for elementary-secondary migrant children. Complementing the secondary level job information text and a workbook about decision making and self-awareness, the work-study guide is designed to accompany work exploration and experience programs. It…

Proposed Site Treatment Plan (PSTP). Volumes 1 and 2 and Reference Document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Helmich, E.; Noller, D.K.; Wierzbicki, K.S.

1994-12-22

The Compliance Plan Volume provides overall schedules with target dates for achieving compliance with the land disposal restrictions (LDR) and contains procedures to establish milestones to be enforced under the Order. Information regarding the technical evaluation of treatment options for SRS mixed wastes is contained in the Background Volume and is provided for informational purposes only.

Analysis of Shroud Options in Support of the Human Exploration of Mars

NASA Technical Reports Server (NTRS)

Feldman, Stuart; Borowski, Stanley; Engelund, Walter; Hundley, Jason; Monk, Timothy; Munk, Michelle

2010-01-01

In support of the Mars Design Reference Architecture (DRA) 5.0, the NASA study team analyzed several shroud options for use on the Ares V launch vehicle.1,2 These shroud options included conventional "large encapsulation" shrouds with outer diameters ranging from 8.4 to 12.9 meters (m) and overall lengths of 22.0 to 54.3 meters, along with a "nosecone-only" shroud option used for Mars transfer vehicle component delivery. Also examined was a "multi-use" aerodynamic encapsulation shroud used for launch, Mars aerocapture, and entry, descent, and landing of the cargo and habitat landers. All conventional shroud options assessed for use on the Mars launch vehicles were the standard biconic design derived from the reference shroud utilized in the Constellation Program s lunar campaign. It is the purpose of this paper to discuss the technical details of each of these shroud options including material properties, structural mass, etc., while also discussing both the volume and mass of the various space transportation and surface system payload elements required to support a "minimum launch" Mars mission strategy, as well as the synergy, potential differences and upgrade paths that may be required between the Lunar and Mars mission shrouds.

Australian Biology Test Item Bank, Years 11 and 12. Volume II: Year 12.

ERIC Educational Resources Information Center

Brown, David W., Ed.; Sewell, Jeffrey J., Ed.

This document consists of test items which are applicable to biology courses throughout Australia (irrespective of course materials used); assess key concepts within course statement (for both core and optional studies); assess a wide range of cognitive processes; and are relevant to current biological concepts. These items are arranged under…

Space station needs, attributes and architectural options study. Volume 7-4B: Data book, architecture, technology and programmatics, part B

NASA Technical Reports Server (NTRS)

1983-01-01

The remote manipulating system, the pointing control system, and the external radiator for the core module of the space station are discussed. The principal interfaces for four basic classes of user and transportation vehicles or facilities associated with the space station were examined.

Australian Biology Test Item Bank, Years 11 and 12. Volume I: Year 11.

ERIC Educational Resources Information Center

Brown, David W., Ed.; Sewell, Jeffrey J., Ed.

This document consists of test items which are applicable to biology courses throughout Australia (irrespective of course materials used); assess key concepts within course statement (for both core and optional studies); assess a wide range of cognitive processes; and are relevant to current biological concepts. These items are arranged under…

Space Station needs, attributes and architectural options study. Volume 7-4A: Data book, architecture, technology and programmatics, part A

NASA Technical Reports Server (NTRS)

1983-01-01

Various parameters of the orbital space station are discussed. The space station environment, data management system, communication and tracking, environmental control, and life support system are considered. Specific topics reviewed include crew work stations, restraint systems, stowage, computer hardware, and expert systems.

Space Station redesign option A: Modular buildup concept

NASA Technical Reports Server (NTRS)

1993-01-01

In early 1993, President Clinton mandated that NASA look at lower cost alternatives to Space Station Freedom. He also established an independent advisory committee - the Blue Ribbon Panel - to review the redesign work and evaluate alternatives. Daniel Goldin, NASA Administrator, established a Station Redesign Team that began operating in late March from Crystal City, Virginia. NASA intercenter teams - one each at Marshall Space Flight Center, Johnson Space Center, and Langley Research Center provided engineering and other support. The results of the Option A study done at Marshall Space Flight Center are summarized. Two configurations (A-1 and A-2) are covered. Additional data is provided in the briefing package MSFC SRT-001, Final System Review to SRT-002, Space Station Option A Modular Buildup Concept, Volumes 1-5, Revision B, June 10, 1993. In June 1993, President Clinton decided to proceed with a modular concept consistent with Option A, and asked NASA to provide an Implementation Plan by September. All data from the Option A redesign activity was provided to NASA's Transition Team for use in developing the Implementation Plan.

Truck Noise X : Noise Reduction Options for Diesel Powered International Harvester Trucks : Volume 1. Development Work.

DOT National Transportation Integrated Search

1977-04-01

Noise reduction option development work was carried out on two inservice diesel powered IH trucks, consisting of a Cab-over model and a Conventional model with a baseline exterior noise level of 87 dB(A) each. Since no specific noise goals were set, ...

78 FR 57913 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-20

... Options Transaction Charge (including the Cabinet Options Transaction Charge) as well as the Broker-Dealer FLEX transaction fee, for members executing facilitation orders pursuant to Exchange Rule 1064 when... average daily volume (including both FLEX and non-FLEX transactions) exceeds 10,000 contracts per day in a...

78 FR 47809 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-06

... the volume, open interest, and trading patterns data that the Exchange proposes to include in the... program. The Exchange noted that the analysis would examine trading in the proposed option product as well...-the-month (``Expiration Friday'') expiration dates, for which the exercise settlement value will be...

Space industrialization. Volume 3: Space industrialization implementation concepts

NASA Technical Reports Server (NTRS)

1978-01-01

Methods for selecting the most viable program options were examined along with techniques for hardware development. Several separate program options were defined, and future plans for space exploitation were reviewed. Hardware elements in various sectors of space are discussed in detail to provide a definition for the major functional elements and operations.

Preretirement Work Options: Evaluation Report. Volume 2.

ERIC Educational Resources Information Center

Holden, Karen C.; And Others

Pre-Retirement Work Options is a demonstration project designed to develop and test alternative employment patterns for older workers in the Wisconsin Civil Service System. The program ws evaluated to determine the interest of older state workers in reducing their work hours prior to retirement as well as the impact of that reduction for those who…

Iran’s Nuclear Program: An Assessment of the Threat to the United States

DTIC Science & Technology

2009-12-01

Mohammad Reza Pahlavi. Peter Haggett, Encyclopedia of World Geography, Volume 15 (Oxfordshire: Andromeda Oxford, 2002), 2,044. 16...Peter. Encyclopedia of World Geography, Volume 15. Oxfordshire: Andromeda Oxford, 2002. Hersh, Seymour. The Samson Option: Israel’s Nuclear Arsenal

Technical options for processing additional light tight oil volumes within the United States

EIA Publications

2015-01-01

This report examines technical options for processing additional LTO volumes within the United States. Domestic processing of additional LTO would enable an increase in petroleum product exports from the United States, already the world’s largest net exporter of petroleum products. Unlike crude oil, products are not subject to export limitations or licensing requirements. While this is one possible approach to absorbing higher domestic LTO production in the absence of a relaxation of current limitations on crude exports, domestic LTO would have to be priced at a level required to encourage additional LTO runs at existing refinery units, debottlenecking, or possible additions of processing capacity.

CIDR

Science.gov Websites

* Minimum # Experimental Samples DNA Volume (ul) Genomic DNA Concentration (ng/ul) Low Input DNA Volume (ul . **Please inquire about additional cost for low input option. Genotyping Minimum # Experimental Samples DNA sample quality. If you do submit WGA samples, you should anticipate a higher non-random missing data rate

Space station data system analysis/architecture study. Task 3: Trade studies, DR-5, volume 1

NASA Technical Reports Server (NTRS)

1985-01-01

The primary objective of Task 3 is to provide additional analysis and insight necessary to support key design/programmatic decision for options quantification and selection for system definition. This includes: (1) the identification of key trade study topics; (2) the definition of a trade study procedure for each topic (issues to be resolved, key inputs, criteria/weighting, methodology); (3) conduct tradeoff and sensitivity analysis; and (4) the review/verification of results within the context of evolving system design and definition. The trade study topics addressed in this volume include space autonomy and function automation, software transportability, system network topology, communications standardization, onboard local area networking, distributed operating system, software configuration management, and the software development environment facility.

Space station needs, attributes and architectural options study. Volume 4: Architectural options, subsystems, technology and programmatics

NASA Technical Reports Server (NTRS)

1983-01-01

Space station architectural options, habitability considerations and subsystem analyses, technology, and programmatics are reviewed. The methodology employed for conceiving and defining space station concepts is presented. As a result of this approach, architectures were conceived and along with their supporting rationale are described within this portion of the report. Habitability consideration and subsystem analyses describe the human factors associated with space station operations and includes subsections covering (1) data management, (2) communications and tracking, (3) environmental control and life support, (4) manipulator systems, (5) resupply, (6) pointing, (7) thermal management and (8) interface standardization. A consolidated matrix of subsystems technology issues as related to meeting the mission needs for a 1990's era space station is presented. Within the programmatics portion, a brief description of costing and program strategies is outlined.

Advanced space system concepts and their orbital support needs (1980 - 2000). Volume 3: Detailed data. Part 1: Catalog of initiatives, functional options, and future environments and goals. [for the U.S. space program

NASA Technical Reports Server (NTRS)

Bekey, I.; Mayer, H. L.; Wolfe, M. G.

1976-01-01

The following areas were discussed in relation to a study of the commonality of space vehicle applications to future national needs: (1) index of initiatives (civilian observation, communication, support), brief illustrated description of each initiative, time periods (from 1980 to 2000+) for implementation of these initiatives; (2) data bank of functional system options, presented in the form of data sheets, one for each of the major functions, with the system option for near-term, midterm, and far-term space projects applicable to each subcategory of functions to be fulfilled; (3) table relating initiatives and desired goals (public service and humanistic, materialistic, scientific and intellectual); and (4) data on size, weight and cost estimations.

RETROFIT COSTS FOR SO2 AND NOX CONTROL OPTIONS AT 200 COAL-FIRED PLANTS, VOLUME IV - SITE SPECIFIC STUDIES FOR MO, MS, NC, NH, NJ, NY, OH

EPA Science Inventory

The report gives results of a study, the objective of which was to significantly improve engineering cost estimates currently being used to evaluate the economic effects of applying SO2 and NOx controls at 200 large SO2-emitting coal-fired utility plants. To accomplish the object...

RETROFIT COSTS FOR SO2 AND NOX CONTROL OPTIONS AT 200 COAL-FIRED PLANTS, VOLUME V - SITE SPECIFIC STUDIES FOR PA, SC, TN, VA, WI, WV

EPA Science Inventory

The report gives results of a study, the objective of which was to significantly improve engineering cost estimates currently being used to evaluate the economic effects of applying SO2 and NOx controls at 200 large SO2-emitting coal-fired utility plants. To accomplish the object...

RETROFIT COSTS FOR SO2 AND NOX CONTROL OPTIONS AT 200 COAL-FIRED PLANTS, VOLUME II - SITE SPECIFIC STUDIES FOR AL, DE. FL, GA, IL

EPA Science Inventory

The report gives results of a study, the objective of which was to significantly improve engineering cost estimates currently being used to evaluate the economic effects of applying SO2 and NOx controls at 200 large SO2-emitting coal-fired utility plants. To accomplish the object...

RETROFIT COSTS FOR SO2 AND NOX CONTROL OPTIONS AT 200 COAL-FIRED PLANTS, VOLUME III - SITE SPECIFIC STUDIES FOR IN, KY, MA, MD, MI, MN

EPA Science Inventory

The report gives results of a study, the objective of which was to significantly improve engineering cost estimates currently being used to evaluate the economic effects of applying SO2 and NOx controls at 200 large SO2-emitting coal-fired utility plants. To accomplish the object...

Solar power satellite. System definition study. Part 1, volume 5: SPS transportation. Representative system descriptions

NASA Technical Reports Server (NTRS)

1977-01-01

Both LEO transportation (earth to low earth orbit) and GEO transportation (low earth orbit to geosynchronous orbit) segments were addressed. LEO options include both a 2 stage winged space freighter vehicle and a 2 stage ballistic recoverable vehicle. Both incorporate LO(2)/RP-1/LH(2) engines on the booster and standard SSME's on the upper stage. The orbit transfer vehicle options included chemical for geosynchronous satellite assembly and self powered electric propulsion for low earth orbit satellite assembly. An exhaust products analysis was conducted for the earth to LEO vehicle since atmospheric pollution could be a concern.

Mathematical modelling of tumour volume dynamics in response to stereotactic ablative radiotherapy for non-small cell lung cancer

NASA Astrophysics Data System (ADS)

Tariq, Imran; Humbert-Vidan, Laia; Chen, Tao; South, Christopher P.; Ezhil, Veni; Kirkby, Norman F.; Jena, Rajesh; Nisbet, Andrew

2015-05-01

This paper reports a modelling study of tumour volume dynamics in response to stereotactic ablative radiotherapy (SABR). The main objective was to develop a model that is adequate to describe tumour volume change measured during SABR, and at the same time is not excessively complex as lacking support from clinical data. To this end, various modelling options were explored, and a rigorous statistical method, the Akaike information criterion, was used to help determine a trade-off between model accuracy and complexity. The models were calibrated to the data from 11 non-small cell lung cancer patients treated with SABR. The results showed that it is feasible to model the tumour volume dynamics during SABR, opening up the potential for using such models in a clinical environment in the future.

Women and Work--New Options. A Guide to Nonprint Media.

ERIC Educational Resources Information Center

Artel, Linda; Wheat, Valerie

The purpose of this guide is to gather together in one volume information about nonprint media dealing with new career options for women. The 112 films, filmstrips, videotapes and cassettes, slides, photograph sets and games included in the guide are listed in alphabetical order by title. For each entry the following information is provided:…

78 FR 75644 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-12

... Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate Effectiveness of a Proposed Rule Change... thresholds required to achieve each volume tier and will issue an information circular to inform Participants... calculation is pro- competitive and will result in lower total costs to Participants, a positive [[Page 75645...

Rural Schools Prototype Analysis. Volume I: Design, Determinants and Options.

ERIC Educational Resources Information Center

Construction Systems Management, Inc., Anchorage, AK.

This resource guide presents Design Determinants and Options to be used by designers, school district personnel, and State officials in the programing and design of small rural secondary schools in the Alaska bush. The vast and unconventional educational and space planning challenge is compounded by: the need to provide most or all of the…

Truck Noise X : Noise Reduction Options for Diesel Powered International Harvester Trucks : Volume 2. Cost-Noise Analysis and Field Installation.

DOT National Transportation Integrated Search

1977-04-01

Noise reduction option development work was carried out on two inservice diesel powered IH trucks, consisting of a Cab-over model and a Conventional model with a baseline exterior noise level of 87 dB(A) each. Since no specific noise goals were set, ...

77 FR 60504 - Self-Regulatory Organizations; C2 Options Exchange, Incorporated; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

.... The Exchange recently submitted this Annual Report, which contains an analysis of volume, open interest, and trading patterns. The analysis examines trading in the proposed option product as well as... Friday'') for which the exercise settlement value was to be based on the index value derived from the...

RETROFIT COSTS FOR SO2 AND NOX CONTROL OPTIONS AT 200 COAL-FIRED PLANTS, VOLUME I - INTRODUCTION AND METHODOLOGY

EPA Science Inventory

The report gives results of a study, the objective of which was to significantly improve engineering cost estimates currently being used to evaluate the economic effects of applying SO2 and NOx controls at 200 large SO2-emitting coal-fired utility plants. To accomplish the object...

Space station needs, attributes, and architectural options study. Volume 1: Missions and requirements

NASA Technical Reports Server (NTRS)

1983-01-01

Science and applications, NOAA environmental observation, commercial resource observations, commercial space processing, commercial communications, national security, technology development, and GEO servicing are addressed. Approach to time phasing of mission requirements, system sizing summary, time-phased user mission payload support, space station facility requirements, and integrated time-phased system requirements are also addressed.

Satellite services system analysis study. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1981-01-01

Service requirements are considered. Topics include development of on-orbit operations scenarios, service equipment summary, crew interaction, and satellite features facilitating servicing. Service equipment concepts are considered. Topics include payload deployment, close proximity retrieval, on-orbit servicing, backup/contingency, delivery/retrieval of high energy payloads, Earth return, optional service, and advanced capabilities. Program requirements are assessed.

A study of space station needs, attributes and architectural options, volume 2, technical. Book 3: Economic benefits, costs and programmatics

NASA Technical Reports Server (NTRS)

1983-01-01

The economic benefits, cost analysis, and industrial uses of the manned space station are investigated. Mission payload costs are examined in relation to alternative architectures and projected technological evolution. Various approaches to industrial involvement for financing, development, and marketing of space station resources are described.

Young-stand management options and their implications for wood quality and other values.

Treesearch

R. James Barbour; Richard R. Zaborskeb; Michael H. McClellan; Linda Christian; Donald. Golnick

2005-01-01

This study used the forest vegetation Simulator (FVS), empirical wood product recovery information, and expert judgments to examine volume production and potential revenues for different silvicultural prescriptions grown to rotation ages of 70, 110, and 150 years. Our intention was to provide policymakers and managers with some of the information needed to evaluate the...

Documentation of the GLAS fourth order general calculation model. Volume 3: Vectorized code for the Cyber 205

NASA Technical Reports Server (NTRS)

Kalnay, E.; Balgovind, R.; Chao, W.; Edelmann, D.; Pfaendtner, J.; Takacs, L.; Takano, K.

1983-01-01

Volume 3 of a 3-volume technical memoranda which contains documentation of the GLAS fourth order genera circulation model is presented. The volume contains the CYBER 205 scalar and vector codes of the model, list of variables, and cross references. A dictionary of FORTRAN variables used in the Scalar Version, and listings of the FORTRAN Code compiled with the C-option, are included. Cross reference maps of local variables are included for each subroutine.

An economic analysis of four options for dealing with low-volume roads in energy-impacted areas of Texas.

DOT National Transportation Integrated Search

2014-10-01

The Texas A&M Transportation Institute undertook an economic analysis to compare the costs of : maintaining a typical Texas low-volume road in an energy-impacted area in its current state versus widening : and maintaining the road; converting it to a...

40 CFR 86.1823-08 - Durability demonstration procedures for exhaust emissions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES (CONTINUED) General Compliance Provisions for Control of Air Pollution From New and In... § 86.1801. Eligible small volume manufacturers or small volume test groups may optionally meet the...

40 CFR 86.1823-08 - Durability demonstration procedures for exhaust emissions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES (CONTINUED) General Compliance Provisions for Control of Air Pollution From New and In... § 86.1801. Eligible small volume manufacturers or small volume test groups may optionally meet the...

CTIC Cablebooks. Volume 2: A Guide for Local Policy.

ERIC Educational Resources Information Center

Jesuale, Nancy, Ed.; And Others

The second in a two-part series, this volume presents 13 chapters discussing many of the most pressing cable policy issues facing local government, describing alternative policy options, and suggesting regulatory procedures successfully used by decision makers in the United States. Topics covered are (1) "The Rationale for Regulation,"…

Interior design of the lunar outpost

NASA Technical Reports Server (NTRS)

Kennedy, Kriss J.

1990-01-01

This paper is part of an ongoing study on the interior design of a lunar outpost habitat facility. The concept presented represents the work done up to and including August 1989. This concept is part of NASA's ongoing effort to explore alternative options for planet surface systems habitation. Results of a volume analog study to determine the required pressurized volume are presented along with an internal layout of the habitat facility. The concept presented in this paper is a constructible lunar habitat that provides a living and working environment for a crew of 12. It is a 16-m diameter spherical pneumatic structure which contains 2145 cubic meters of volume. Five levels of living and working areas make up the 742 sq m of floor space. A 2-m vertical circulation shaft at the center allows for transfer of crew and equipment.

Energy research with neutrons (ErwiN) and installation of a fast neutron powder diffraction option at the MLZ, Germany1

PubMed Central

Mühlbauer, Martin J.

2018-01-01

The need for rapid data collection and studies of small sample volumes in the range of cubic millimetres are the main driving forces for the concept of a new high-throughput monochromatic diffraction instrument at the Heinz Maier-Leibnitz Zentrum (MLZ), Germany. A large region of reciprocal space will be accessed by a detector with sufficient dynamic range and microsecond time resolution, while allowing for a variety of complementary sample environments. The medium-resolution neutron powder diffraction option for ‘energy research with neutrons’ (ErwiN) at the high-flux FRM II neutron source at the MLZ is foreseen to meet future demand. ErwiN will address studies of energy-related systems and materials with respect to their structure and uniformity by means of bulk and spatially resolved neutron powder diffraction. A set of experimental options will be implemented, enabling time-resolved studies, rapid parametric measurements as a function of external parameters and studies of small samples using an adapted radial collimator. The proposed powder diffraction option ErwiN will bridge the gap in functionality between the high-resolution powder diffractometer SPODI and the time-of-flight diffractometers POWTEX and SAPHiR at the MLZ. PMID:29896055

Dual mobility cups provide biomechanical advantages in situations at risk for dislocation: a finite element analysis.

PubMed

Terrier, Alexandre; Latypova, Adeliya; Guillemin, Maika; Parvex, Valérie; Guyen, Olivier

2017-03-01

Constrained devices, standard implants with large heads, and dual mobility systems have become popular options to manage instability after total hip arthroplasty (THA). Clinical results with these options have shown variable success rates and significant higher rates of aseptic loosening and mechanical failures with constrained implants. Literature suggests potential advantages of dual mobility, however little is known about its biomechanics. We present a comparative biomechanical study of a standard implant, a constrained implant, and a dual mobility system. A finite element analysis was developed to assess and compare these acetabular options with regard to the range of motion (ROM) to impingement, the angle of dislocation, the resistive torque, the volume of polyethylene (PE) with a stress above 80% of the elastic limit, and the interfacial cup/bone stress. Dual mobility implants provided the greatest ROM to impingement and allowed delaying subluxation and dislocation when compared to standard and constrained implants. Dual mobility also demonstrated the lowest resistive torque at subluxation while the constrained implant provided the greatest one. The lowest critical PE volume was observed with the dual mobility implant, and the highest stress at the interfaces was observed with the constrained implant. This study highlights the biomechanical advantages of dual mobility systems over constrained and standard implants, and is supported by the clinical results reported. Therefore, the use of dual mobility systems in situations at risk for instability should be advocated and constrained implants should be restricted to salvage situations.

Arbitrary-Order Conservative and Consistent Remapping and a Theory of Linear Maps: Part II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ullrich, Paul A.; Devendran, Dharshi; Johansen, Hans

2016-04-01

The focus on this series of articles is on the generation of accurate, conservative, consistent, and (optionally) monotone linear offline maps. This paper is the second in the series. It extends on the first part by describing four examples of 2D linear maps that can be constructed in accordance with the theory of the earlier work. The focus is again on spherical geometry, although these techniques can be readily extended to arbitrary manifolds. The four maps include conservative, consistent, and (optionally) monotone linear maps (i) between two finite-volume meshes, (ii) from finite-volume to finite-element meshes using a projection-type approach, (iii)more » from finite-volume to finite-element meshes using volumetric integration, and (iv) between two finite-element meshes. Arbitrary order of accuracy is supported for each of the described nonmonotone maps.« less

Feasibility study for the swaziland/mozambique interconector. Executive summary of the final report. Export trade information

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-11-01

This study, conducted by Black & Veatch, was funded by the U.S. Trade and Development Agency. The report, produced for the Ministry of National Resources, Energy and Environment (MNRE) of Swaziland, determines the least cost capacity expansion option to meet the future power demand and system reliability criteria of Swaziland, with particular emphasis on the propsoed Interconnector between Swaziland and Mozambique. Volume 1 contains the Executive Summary and is divided into the following sections: (1.0) Study Objectives; (2.0) Swaziland and its Economy; (3.0) The Power Sector Structure in Swaziland; (4.0) Electric Power Resources; (5.0) Past Demand Growth; (6.0) Load andmore » Energy Forecasts; (7.0) Need for Power; (8.0) Generation and Transmission Capacity Addition Option; (9.0) SEB Expansion Plan Scenario Development; (10.0) EDM Expansion Plan Development; (11.0) Cost Sharing of the Interconnector; (12.0) Interconnector Options and Environmental Evaluation; (13.0) Generation/Transmission Trade Offs; (14.0) EPC RFP and Draft Interconnection Agreement; (15.0) Transmission System Study; (16.0) Conclusions and Recommendations.« less

Space station ventilation study

NASA Technical Reports Server (NTRS)

Colombo, G. V.; Allen, G. E.

1972-01-01

A ventilation system design and selection method which is applicable to any manned vehicle were developed. The method was used to generate design options for the NASA 33-foot diameter space station, all of which meet the ventilation system design requirements. System characteristics such as weight, volume, and power were normalized to dollar costs for each option. Total system costs for the various options ranged from a worst case $8 million to a group of four which were all approximately $2 million. A system design was then chosen from the $2 million group and is presented in detail. A ventilation system layout was designed for the MSFC space station mockup which provided comfortable, efficient ventilation of the mockup. A conditioned air distribution system design for the 14-foot diameter modular space station, using the same techniques, is also presented. The tradeoff study resulted in the selection of a system which costs $1.9 million, as compared to the alternate configuration which would have cost $2.6 million.

Materials experiment carrier concepts definition study. Volume 2: Technical report, part 2

NASA Technical Reports Server (NTRS)

1981-01-01

A materials experiment carrier (MEC) that provides effective accommodation of the given baseline materials processing in space (MPS) payloads and demonstration of the MPS platform concept for high priority materials processing science, multidiscipline MPS investigations, host carrier for commercial MPS payloads, and system economy of orbital operations is defined. The study flow of task work is shown. Study tasks featured analysis and trades to identify the MEC system concept options.

A data-centric approach to understanding the pricing of financial options

NASA Astrophysics Data System (ADS)

Healy, J.; Dixon, M.; Read, B.; Cai, F. F.

2002-05-01

We investigate what can be learned from a purely phenomenological study of options prices without modelling assumptions. We fitted neural net (NN) models to LIFFE ``ESX'' European style FTSE 100 index options using daily data from 1992 to 1997. These non-parametric models reproduce the Black-Scholes (BS) analytic model in terms of fit and performance measures using just the usual five inputs (S, X, t, r, IV). We found that adding transaction costs (bid-ask spread) to these standard five parameters gives a comparable fit and performance. Tests show that the bid-ask spread can be a statistically significant explanatory variable for option prices. The difference in option prices between the models with transaction costs and those without ranges from about -3.0 to +1.5 index points, varying with maturity date. However, the difference depends on the moneyness (S/X), being greatest in-the-money. This suggests that use of a five-factor model can result in a pricing difference of up to #10 to #30 per call option contract compared with modelling under transaction costs. We found that the influence of transaction costs varied between different yearly subsets of the data. Open interest is also a significant explanatory variable, but volume is not.

75 FR 22884 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

... uniform time frame for the introduction of new LEAPS on equity option classes, options on exchange traded... minimum volume threshold per underlying class to qualify for the introduction of a new expiration year of... 30 days from the date on which it was filed, or such shorter time as the Commission may designate if...

75 FR 51126 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

... accordance with Rule 6.24. \\6\\ The term OTP refers to an Options Trading Permit issued by the Exchange for... Ex-by-Ex threshold, coupled with the dramatic increase in option trading volume from 2003 to 2009... and the increase in trading, the existing deadline for submitting CEAs to the Exchange is problematic...

17 CFR 16.01 - Publication of market data on futures, swaps and options thereon: trading volume, open contracts...

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Publication of market data on... MARKETS AND SWAP EXECUTION FACILITIES § 16.01 Publication of market data on futures, swaps and options.... (1) Each reporting market, as defined in part 15 of this chapter, must separately record for each...

17 CFR 16.01 - Publication of market data on futures, swaps and options thereon: trading volume, open contracts...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Publication of market data on... MARKETS AND SWAP EXECUTION FACILITIES § 16.01 Publication of market data on futures, swaps and options.... (1) Each reporting market, as defined in part 15 of this chapter, must separately record for each...

Nondegree Options for Expanding a Leadership Portfolio.

PubMed

Bleich, Michael R; Jones-Schenk, Jan

2016-07-01

Organizational leaders are time-challenged to stay attuned with dynamic health care and business environments, leaving time for professional development at a premium. Beyond interorganizational leadership programs, learning options for nondegree-enhanced education are provided, referencing some of the high-quality, high-volume programs available at no or low cost. J Contin Educ Nurs. 2016;47(7):299-301. Copyright 2016, SLACK Incorporated.

78 FR 29422 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-20

... customer volume in multiply-listed options classes over the course of a month (putting that affiliate at... Market- Maker arms. CBOE wants to be aware not only of the importance of providing credits on the order... also provide credits to Market-Makers if a Market-Maker's affiliate's adds a certain amount of customer...

National facilities study. Volume 2A: Facility Study Office on the National Wind Tunnel Complex

NASA Technical Reports Server (NTRS)

1994-01-01

The Facility Study Office (FSO) has completed its assigned activities. The results of the FSO efforts, studies, and assessments are documented. An overview of the FSO activities as well as a general comparison of all concepts considered are provided. Detailed information is also provided for the selected concept, Concept D-Option 5. Only findings are presented. The FSO developed recommendations only as a consequence of assumptions for cost and schedule assessments.

Mars power system concept definition study. Volume 1: Study results

NASA Technical Reports Server (NTRS)

Littman, Franklin D.

1994-01-01

A preliminary top level study was completed to define power system concepts applicable to Mars surface applications. This effort included definition of power system requirements and selection of power systems with the potential for high commonality. These power systems included dynamic isotope, Proton Exchange Membrane (PEM) regenerative fuel cell, sodium sulfur battery, photovoltaic, and reactor concepts. Design influencing factors were identified. Characterization studies were then done for each concept to determine system performance, size/volume, and mass. Operations studies were done to determine emplacement/deployment maintenance/servicing, and startup/shutdown requirements. Technology development roadmaps were written for each candidate power system (included in Volume 2). Example power system architectures were defined and compared on a mass basis. The dynamic isotope power system and nuclear reactor power system architectures had significantly lower total masses than the photovoltaic system architectures. Integrated development and deployment time phasing plans were completed for an example DIPS and reactor architecture option to determine the development strategies required to meet the mission scenario requirements.

CTIC Cablebooks. Volume 1: The Community Medium.

ERIC Educational Resources Information Center

Jesuale, Nancy, Ed.; Smith, Ralph Lee, Ed.

The first of a two-part series, this volume addresses the broad scope of questions and issues that confront local governments when formulating or reevaluating cable policy. In 11 chapters, 14 authors present an historical perspective and discuss cable technology and state-of-the-art options: (1) "Overview of Cable TV Services and…

78 FR 71731 - 2014 Standards for the Renewable Fuel Standard Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-29

... of E85 Consumption c. Proposed Projection of E85 Consumption in 2014 d. Estimating Total Ethanol Consumption in 2014 2. Estimating Availability of Non-Ethanol Renewable Fuel Volumes a. Non-Ethanol Cellulosic... Biofuel c. Option 3: Availability, Growth, and Limits on Ethanol Consumption D. Summary of Proposed Volume...

Australian Family Research Conference Proceedings (Canberra, Australia, November 23-25, 1983). Volume IV: Policies and Families.

ERIC Educational Resources Information Center

Institute of Family Studies, Melbourne (Australia).

Fourth in a series of volumes containing the proceedings of the 1983 Australian Family Research Conference, this publication deals with policies and families in Australia. Papers and authors included are: "Improving Social Security Programs: Some Options and Barriers" (Andrew Burbidge), "Single Parent Families and Social Policies:…

A comparison of center-based vs. home-based daily hemodialysis for patients with end-stage renal disease.

PubMed

Kraus, Michael; Burkart, John; Hegeman, Rebecca; Solomon, Richard; Coplon, Norman; Moran, John

2007-10-01

Home hemodialysis has been a therapeutic option for almost 4 decades. The complexity of dialysis equipment has been a factor-limiting adoption of this modality. We performed a feasibility study to demonstrate the safety of center-based vs. home-based daily hemodialysis with the NxStage System One portable hemodialysis device. We also performed a retrospective analysis to determine if clinical effects previously associated with short-daily dialysis were also seen using this novel device. We conducted a prospective, 2-treatment, 2-period, open-label, crossover study of in-center hemodialysis vs. home hemodialysis in 32 patients treated at 6 U.S. centers. The 8-week In-Center Phase (6 days/week) was followed by a 2-week transition period and then followed by the 8-week Home Phase (6 days/week). We retrospectively collected data on hemodialysis treatment parameters immediately preceding the study in a subset of patients. Twenty-six out of 32 patients (81%) successfully completed the study. Successful delivery of at least 90% of prescribed fluid volume (primary endpoint) was achieved in 98.5% of treatments in-center and 97.3% at home. Total effluent volume as a percentage of prescribed volume was between 94% and 100% for all study weeks. The composite rate of intradialytic and interdialytic adverse events per 100 treatments was significantly higher for the In-Center Phase (5.30) compared with the Home Phase (2.10; p=0.007). Compared with the period immediately preceding the study, there were reductions in blood pressure, antihypertensive medications, and interdialytic weight gain. Daily home hemodialysis with a small, easy-to-use hemodialysis device is a viable dialysis option for end-stage renal disease patients capable of self/partner-administered dialysis.

Space station needs, attributes and architectural options study. Volume 3: Requirements

NASA Technical Reports Server (NTRS)

1983-01-01

A typical system specification format is presented and requirements are compiled. A Program Specification Tree is shown showing a high inclination space station and a low inclination space station with their typical element breakdown, also represented along the top blocks are the interfaces with other systems. The specification format is directed at the Low Inclination space station.

Space station needs, attributes and architectural options study. Volume 3: Mission requirements

NASA Technical Reports Server (NTRS)

1983-01-01

User missions that are enabled or enhanced by a manned space station are identified. The mission capability requirements imposed on the space station by these users are delineated. The accommodation facilities, equipment, and functional requirements necessary to achieve these capabilities are identified, and the economic, performance, and social benefits which accrue from the space station are defined.

Space station propulsion-ECLSS interaction study

NASA Technical Reports Server (NTRS)

Brennan, Scott M.

1986-01-01

The benefits of the utilization of effluents of the Space Station Environmental Control and Life Support (ECLS) system are examined. Various ECLSS-propulsion system interaction options are evaluated and compared on the basis of weight, volume, and power requirements. Annual propulsive impulse to maintain station altitude during a complete solar cycle of eleven years and the effect on station resupply are considered.

SU-F-T-538: CyberKnife with MLC for Treatment of Large Volume Tumors: A Feasibility Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bichay, T; Mayville, A

2016-06-15

Purpose: CyberKnife is a well-documented modality for SRS and SBRT treatments. Typical tumors are small and 1–5 fractions are usually used. We determined the feasibility of using CyberKnife, with an InCise multileaf collimator option, for larger tumors undergoing standard dose and fractionation. The intent was to understand the limitation of using this modality for other external beam radiation treatments. Methods: Five tumors from different anatomical sites with volumes from 127.8 cc to 1,320.5 cc were contoured and planned on a Multiplan V5.1 workstation. The target average diameter ranged from 7 cm to 13 cm. The dose fractionation was 1.8–2.0 Gy/fractionmore » and 25–45 fractions for total doses of 45–81 Gy. The sites planned were: pancreas, head and neck, prostate, anal, and esophagus. The plans were optimized to meet conventional dose constraints based on various RTOG protocols for conventional fractionation. Results: The Multiplan treatment planning system successfully generated clinically acceptable plans for all sites studied. The resulting dose distributions achieved reasonable target coverage, all greater than 95%, and satisfactory normal tissue sparing. Treatment times ranged from 9 minutes to 38 minutes, the longest being a head and neck plan with dual targets receiving different doses and with multiple adjacent critical structures. Conclusion: CyberKnife, with the InCise multileaf collimation option, can achieve acceptable dose distributions in large volume tumors treated with conventional dose and fractionation. Although treatment times are greater than conventional accelerator time; target coverage and dose to critical structures can be kept within a clinically acceptable range. While time limitations exist, when necessary CyberKnife can provide an alternative to traditional treatment modalities for large volume tumors.« less

Computational Study of a McDonnell Douglas Single-Stage-to-Orbit Vehicle Concept for Aerodynamic Analysis

NASA Technical Reports Server (NTRS)

Prabhu, Ramadas K.

1996-01-01

This paper presents the results of a computational flow analysis of the McDonnell Douglas single-stage-to-orbit vehicle concept designated as the 24U. This study was made to determine the aerodynamic characteristics of the vehicle with and without body flaps over an angle of attack range of 20-40 deg. Computations were made at a flight Mach number of 20 at 200,000 ft. altitude with equilibrium air, and a Mach number of 6 with CF4 gas. The software package FELISA (Finite Element Langley imperial College Sawansea Ames) was used for all the computations. The FELISA software consists of unstructured surface and volume grid generators, and inviscid flow solvers with (1) perfect gas option for subsonic, transonic, and low supersonic speeds, and (2) perfect gas, equilibrium air, and CF4 options for hypersonic speeds. The hypersonic flow solvers with equilibrium air and CF4 options were used in the present studies. Results are compared with other computational results and hypersonic CF4 tunnel test data.

Exploring the biophysical option space for feeding the world without deforestation.

PubMed

Erb, Karl-Heinz; Lauk, Christian; Kastner, Thomas; Mayer, Andreas; Theurl, Michaela C; Haberl, Helmut

2016-04-19

Safeguarding the world's remaining forests is a high-priority goal. We assess the biophysical option space for feeding the world in 2050 in a hypothetical zero-deforestation world. We systematically combine realistic assumptions on future yields, agricultural areas, livestock feed and human diets. For each scenario, we determine whether the supply of crop products meets the demand and whether the grazing intensity stays within plausible limits. We find that many options exist to meet the global food supply in 2050 without deforestation, even at low crop-yield levels. Within the option space, individual scenarios differ greatly in terms of biomass harvest, cropland demand and grazing intensity, depending primarily on the quantitative and qualitative aspects of human diets. Grazing constraints strongly limit the option space. Without the option to encroach into natural or semi-natural land, trade volumes will rise in scenarios with globally converging diets, thereby decreasing the food self-sufficiency of many developing regions.

CDK4/6 dual inhibitor abemaciclib demonstrates compelling preclinical activity against esophageal adenocarcinoma: a novel therapeutic option for a deadly disease.

PubMed

Kosovec, Juliann E; Zaidi, Ali H; Omstead, Ashten N; Matsui, Daisuke; Biedka, Mark J; Cox, Erin J; Campbell, Patrick T; Biederman, Robert W W; Kelly, Ronan J; Jobe, Blair A

2017-11-21

Esophageal adenocarcinoma (EAC) is a deadly disease with limited therapeutic options. In the present study, we determined the preclinical efficacy of CDK4/6 inhibitor abemaciclib for treatment of EAC. In vitro , apoptosis, proliferation, and pathway regulation were evaluated in OE19, OE33, and FLO1 EAC cell lines. In vivo , esophagojejunostomy was performed on rats to induce EAC. At 36 weeks post-surgery, MRI and endoscopic biopsy established baseline tumor volume and molecular correlates, respectively. Next, the study animals were randomized to 26mg/kg intraperitoneal abemaciclib treatment or vehicle control for 28 days. Pre and post treatment MRIs, histopathology, and qRT-PCR were utilized to determine response. Our results demonstrated treatment with abemaciclib lead to increased apoptosis, and decreased proliferation in OE19 (p=0.185), OE33 (p=0.048), and FLO1 (p=0.043) with anticipated downstream molecular inhibition. In vivo , 78.9% of treatment animals demonstrated >20% tumor volume decrease (placebo 0%). Mean tumor volume changed in the treatment arm by -65.5% (placebo +133.5%) (p<0.01), and prevalence changed by -37.5% (placebo +16.7%) (p<0.01). Pre vs post treatment qRT-PCR demonstrated significant inhibition of all downstream molecular correlates. Overall our findings suggest potent antitumor efficacy of abemaciclib against EAC with evident molecular pathway inhibition and reasonable safety, establishing the rationale for future clinical development.

Parents Pleased With Child Care Options and Quality. Research Brief, Volume 96, Number 4

ERIC Educational Resources Information Center

Public Policy Forum, 2008

2008-01-01

A recent survey of 430 parents in southeastern Wisconsin finds the majority are satisfied with the quality of their child care arrangements and their options for child care. Most say they would not change anything about their child care arrangement if they had the chance, and nearly two-thirds report a willingness to pay more for their current…

Space tug point design study. Volume 3: Design definition. Part 1: Propulsion and mechanical, avionics, thermal control and electrical power subsystems

NASA Technical Reports Server (NTRS)

1973-01-01

A study was conducted to determine the configuration and performance of a space tug. Details of the space tug systems are presented to include: (1) propulsion systems, (2) avionics, (3) thermal control, and (4) electric power subsystems. The data generated include engineering drawings, schematics, subsystem operation, and component description. Various options investigated and the rational for the point design selection are analyzed.

Airport and Airway Costs: Allocation and Recovery in the 1980’s.

DTIC Science & Technology

1987-02-01

1997 [8]. 3*X S.% Volume 4, FAA Cost Recovery Options [9). Volume 5, Econometric Cost Functions for FAA Cost Allocation Model [10]. Volume 6, Users...and relative price elasticities ( Ramsey pricing technique). User fees based on the Ramsey pricing tend to be less burdensome on users and minimize...full discussion of the Ramsey pricing techniques is provided in Allocation of Federal Airport and Airway Costs for FY 1985 [6]. -12- In step 5

Effect of advanced aircraft noise reduction technology on the 1990 projected noise environment around Patrick Henry Airport. [development of noise exposure forecast contours for projected traffic volume and aircraft types

NASA Technical Reports Server (NTRS)

Cawthorn, J. M.; Brown, C. G.

1974-01-01

A study has been conducted of the future noise environment of Patric Henry Airport and its neighboring communities projected for the year 1990. An assessment was made of the impact of advanced noise reduction technologies which are currently being considered. These advanced technologies include a two-segment landing approach procedure and aircraft hardware modifications or retrofits which would add sound absorbent material in the nacelles of the engines or which would replace the present two- and three-stage fans with a single-stage fan of larger diameter. Noise Exposure Forecast (NEF) contours were computed for the baseline (nonretrofitted) aircraft for the projected traffic volume and fleet mix for the year 1990. These NEF contours are presented along with contours for a variety of retrofit options. Comparisons of the baseline with the noise reduction options are given in terms of total land area exposed to 30 and 40 NEF levels. Results are also presented of the effects on noise exposure area of the total number of daily operations.

WASTE AND WATER MANAGEMENT FOR CONVENTIONAL COAL COMBUSTION: ASSESSMENT REPORT - 1979. VOLUME V. DISPOSAL OF FGC (FLUE GAS CLEANING) WASTES

EPA Science Inventory

The report, the fifth of five volumes, focuses on disposal of coal ash and FGD wastes which (together) comprise FGC wastes. The report assesses the various options for the disposal of FGC wastes with emphasis on disposal on land. A number of technical, economic, and regulatory fa...

NCRVE Change Agent. Shaping the Future of Vocational Education. Volume 4, 1994.

ERIC Educational Resources Information Center

NCRVE Change Agent, 1994

1994-01-01

The first of four issues in this volume consists of four review articles. "Tech Prep Quality" reviews a guide to total quality management and tech prep. "Specific, Ocean to Ocean" reviews a publication that identifies 10 preliminary plans for implementing tech prep. "...No Single Option" is about a monograph that evaluates tech prep and other…

Using higher doses to compensate for tubing residuals in extended-infusion piperacillin-tazobactam.

PubMed

Lam, Wendy J; Bhowmick, Tanaya; Gross, Alan; Vanschooneveld, Trevor C; Weinstein, Melvin P

2013-06-01

To mathematically assess drug losses due to infusion line residuals and evaluate methods to compensate for drug loss due to residual volumes in intravenous pump tubing. Literature was accessed through Ovid MEDLINE (1996-February 2013), using combinations of the search terms tubing residuals, residual volume, residual medication, intravenous infusions, intravenous injections, piperacillin, piperacillin-tazobactam, β-lactams, equipment design, infusion pumps, extended infusion, extended administration, and prolonged infusion. In addition, select reference citations from publications identified were reviewed. All articles that involved extended-infusion piperacillin-tazobactam implementation strategies were included in the review. Infusion pump characteristics and tubing residuals can affect extended-infusion piperacillin-tazobactam dosing strategies. Two studies addressing tubing residuals were identified. Both studies recommended increasing infusion volumes to compensate for tubing residuals. One study also recommended decreasing infusion-line dead space by using alternative infusion pump systems. Study calculations suggest that higher doses of piperacillin-tazobactam may be used to account for medication left in tubing residuals if alternative infusion pump systems cannot be obtained, and increased infusion volumes are not an option. Extended-infusion piperacillin-tazobactam has been used as a method of maximizing pharmacodynamic target attainment. Use of higher doses of piperacillin-tazobactam may be a reasonable method to compensate for drug loss due to residual volumes in large-bore intravenous pump tubing.

A comparative life-cycle assessment of briquetting logging residues and lumber manufacturing coproducts in western United States

Treesearch

Sevda Alanya-Rosenbaum; Richard D. Bergman; Indroneil Ganguly; Francesca Pierobon

2018-01-01

Timber harvest activities in the western United States have resulted in large volumes of low- to no-value logging (forest) residues. Alternatives to pile-and-burning are needed to best utilize this material and to mitigate the resultant environmental impacts. Briquetting (densifying) forest residues near-woods is one such option and is the focus of this study. This...

Sociolinguistics: Current Trends and Prospects; Report of the 23rd Annual Round Table Meeting on Linguistics and Language Studies. Monograph Series on Language and Linguistics No. 25.

ERIC Educational Resources Information Center

Shuy, Roger W., Ed.

The papers included in this volume discuss the relationship of sociolinguistics to social interaction, sociolinguistic surveys, the intersection of sociolinguistics with education, and the influence of linguistics and sociology on sociolinguistics. The papers include: "Optional Rules in Grammar" (Fraser); "The Structure of Polylectal Grammars"…

42 CFR 413.312 - Methodology for calculating rates.

Code of Federal Regulations, 2013 CFR

2013-10-01

... SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost Reporting Periods Beginning...

42 CFR 413.312 - Methodology for calculating rates.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost Reporting Periods Beginning...

Advanced On-The-Job Training System: User’s Handbook (Sections 10-11). Volume 3

DTIC Science & Technology

1990-05-01

leWd 4. idsodity a ne bety position Quit This Plan Select Option: Z (i)d4L.-tti irman Ifrom List, ()nter Specific S, (q)uit ? I 10-2.-4 0 The AOTS...Print SUperviaima List q. Rit This Plans Select Option: S 10-44 STEP 6: SELECT THE SUPERVISION LIST OPTION. Enter 5 and press 3RETU 30 D RA FT AOTS...training is accomplished by the trainee completing an on-line CAI lesson , while for other tasks, knowledge training is accomplished off line by the trainee

Evaluating a Small Structural Insulated Panel (SIP) Designed Solar Kiln in Southwestern New Mexico - Part 1

Treesearch

Richard D. Bergman; Ted E.M. Bilek

2012-01-01

With increasing energy costs, using small dry kilns for drying lumber for small-volume value-added wood products has become more of an option when compared with conventional drying. Small solar kilns are one such option, and a number of solar kiln designs exist and are in use. However, questions remain about the design and operation of solar kilns, particularly during...

42 CFR 413.321 - Simplified cost report for SNFs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost Reporting Periods Beginning...

42 CFR 413.321 - Simplified cost report for SNFs.

Code of Federal Regulations, 2013 CFR

2013-10-01

... SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost Reporting Periods Beginning...

Optimizing parameter choice for FSL-Brain Extraction Tool (BET) on 3D T1 images in multiple sclerosis.

PubMed

Popescu, V; Battaglini, M; Hoogstrate, W S; Verfaillie, S C J; Sluimer, I C; van Schijndel, R A; van Dijk, B W; Cover, K S; Knol, D L; Jenkinson, M; Barkhof, F; de Stefano, N; Vrenken, H

2012-07-16

Brain atrophy studies often use FSL-BET (Brain Extraction Tool) as the first step of image processing. Default BET does not always give satisfactory results on 3DT1 MR images, which negatively impacts atrophy measurements. Finding the right alternative BET settings can be a difficult and time-consuming task, which can introduce unwanted variability. To systematically analyze the performance of BET in images of MS patients by varying its parameters and options combinations, and quantitatively comparing its results to a manual gold standard. Images from 159 MS patients were selected from different MAGNIMS consortium centers, and 16 different 3DT1 acquisition protocols at 1.5 T or 3T. Before running BET, one of three pre-processing pipelines was applied: (1) no pre-processing, (2) removal of neck slices, or (3) additional N3 inhomogeneity correction. Then BET was applied, systematically varying the fractional intensity threshold (the "f" parameter) and with either one of the main BET options ("B" - bias field correction and neck cleanup, "R" - robust brain center estimation, or "S" - eye and optic nerve cleanup) or none. For comparison, intracranial cavity masks were manually created for all image volumes. FSL-FAST (FMRIB's Automated Segmentation Tool) tissue-type segmentation was run on all BET output images and on the image volumes masked with the manual intracranial cavity masks (thus creating the gold-standard tissue masks). The resulting brain tissue masks were quantitatively compared to the gold standard using Dice overlap coefficient (DOC). Normalized brain volumes (NBV) were calculated with SIENAX. NBV values obtained using for SIENAX other BET settings than default were compared to gold standard NBV with the paired t-test. The parameter/preprocessing/options combinations resulted in 20,988 BET runs. The median DOC for default BET (f=0.5, g=0) was 0.913 (range 0.321-0.977) across all 159 native scans. For all acquisition protocols, brain extraction was substantially improved for lower values of "f" than the default value. Using native images, optimum BET performance was observed for f=0.2 with option "B", giving median DOC=0.979 (range 0.867-0.994). Using neck removal before BET, optimum BET performance was observed for f=0.1 with option "B", giving median DOC 0.983 (range 0.844-0.996). Using the above BET-options for SIENAX instead of default, the NBV values obtained from images after neck removal with f=0.1 and option "B" did not differ statistically from NBV values obtained with gold-standard. Although default BET performs reasonably well on most 3DT1 images of MS patients, the performance can be improved substantially. The removal of the neck slices, either externally or within BET, has a marked positive effect on the brain extraction quality. BET option "B" with f=0.1 after removal of the neck slices seems to work best for all acquisition protocols. Copyright © 2012 Elsevier Inc. All rights reserved.

Space station data system analysis/architecture study. Task 3: Trade studies, DR-5, volume 2

NASA Technical Reports Server (NTRS)

1985-01-01

Results of a Space Station Data System Analysis/Architecture Study for the Goddard Space Flight Center are presented. This study, which emphasized a system engineering design for a complete, end-to-end data system, was divided into six tasks: (1); Functional requirements definition; (2) Options development; (3) Trade studies; (4) System definitions; (5) Program plan; and (6) Study maintenance. The Task inter-relationship and documentation flow are described. Information in volume 2 is devoted to Task 3: trade Studies. Trade Studies have been carried out in the following areas: (1) software development test and integration capability; (2) fault tolerant computing; (3) space qualified computers; (4) distributed data base management system; (5) system integration test and verification; (6) crew workstations; (7) mass storage; (8) command and resource management; and (9) space communications. Results are presented for each task.

Cost/benefit tradeoffs for reducing the energy consumption of the commercial air transportation system. Volume 1: Technical analysis

NASA Technical Reports Server (NTRS)

Kraus, E. F.

1976-01-01

The effectiveness and associated costs of operational and technical options for reduced fuel consumption by Douglas aircraft in the domestic airline fleet are assessed. Areas explored include alternative procedures for airline and flight operations, advanced and state of the art technology, modification and derivative configurations, new near-term aircraft, turboprop configuration studies, and optimum aircraft geometry. Data for each aircraft studied is presented in tables and graphs.

Specialized Study Options U.S.A., 1986-1988. A Guide to Short-Term Educational Programs in the United States for Foreign Nationals. Volume 2: Professional Development. Second Edition.

ERIC Educational Resources Information Center

Howard, Edrice, Ed.

Information is provided on nearly 500 short-term professional development programs offered in the United States that are open to or intended for non-U.S. students. The programs, which range from 2 weeks to 1 year in length, require at least an associate's degree or a corresponding level of academic or nonacademic study for admission. The programs…

Anatomical basis of the extended TDAP flap: study of its territories of vascularization and its volume.

PubMed

Dast, Sandy; Havet, Eric; Dessena, Lidia; Abdulshakoor, Abeer; Alharbi, Mohammed; Vaucher, Richard; Herlin, Christian; Sinna, Raphael

2017-08-01

The concept of extended thoracodorsal artery perforator (TDAP) flap was described in 2015 for breast reconstruction. Our anatomical study aims to identify the territories vascularised by the thoracodorsal artery perforator via the deep muscular fascial network. The second goal was to define the volume of the extended TDAP flap. Ten extended TDAP flaps were dissected on 5 fresh human cadavers. Around the classical skin paddle of a TDAP flap, the dissections were performed in a subfascial level, including the muscular fascia and the adipose tissue compartments to increase the volume of the flap. After injection of methylene blue in the thoracodorsal artery, we measured the length and width, the surface and the volume of the coloured flap. The mean sizes of the extended TDAP flap were 24.9 cm × 20.1 cm. The mean surface of the total vascularization zone was 441 cm 2 . The mean volume of the vascularized flap was 193 ml. The thoracodorsal artery perforator via the deep muscular fascial network allows us to harvest a flap of 25 cm × 20 cm with a mean surface of 441 cm² and a mean volume of 193 ml. The extended TDAP flap is a credible option in breast reconstruction.

42 CFR 413.304 - Eligibility for prospectively determined payment rates.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-STAGE RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost...

42 CFR 413.316 - Determining payment amounts: Ancillary services.

Code of Federal Regulations, 2010 CFR

2010-10-01

... RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost Reporting Periods...

42 CFR 413.316 - Determining payment amounts: Ancillary services.

Code of Federal Regulations, 2013 CFR

2013-10-01

... RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost Reporting Periods...

42 CFR 413.304 - Eligibility for prospectively determined payment rates.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-STAGE RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost...

A study of space station needs, attributes and architectural options. Volume 2: Technical. Book 1: Mission requirements. Appendixes 1 and 2

NASA Technical Reports Server (NTRS)

1983-01-01

The space station mission requirements data base consists of 149 attached and free-flying missions each of which is documented by a set of three interrelated documents: (1) NASA LaRC Data Sheets - with three sheets comprising a set for each payload element described. These sheets contain user payload element data necessary to drive Space Station architectural options. (2) GDC-derived operations descriptions that supplement the LaRC payload element data in the operations areas such as further descriptions of crew involvement, EVA, etc. (3) Payload elements synthesis sheets used by GDC to provide requirements traceability to data sources and to provide a narrative describing the basis for formulating the payload element requirements.

Space Station needs, attributes and architectural options. Volume 2, book 2, part 1: Mission implementation concepts

NASA Technical Reports Server (NTRS)

1983-01-01

The overall configuration and modules of the initial and evolved space station are described as well as tended industrial and polar platforms. The mass properties that are the basis for costing are summarized. User friendly attributes (interfaces, resources, and facilities) are identified for commercial; science and applications; industrial park; international participation; national security; and the external tank option. Configuration alternates studied to determine a baseline are examined. Commonality for clustered 3-man and 9-man stations are considered as well as the use of tethered platforms. Requirements are indicated for electrical, communication and tracking; data management Subsystem requirements for electrical, data management, communication and tracking, environment control/life support system; and guidance navigation and control subsystems are identified.

Space Station needs, attributes and architectural options. Volume 2, book 2, part 1: Mission implementation concepts

NASA Astrophysics Data System (ADS)

1983-04-01

The overall configuration and modules of the initial and evolved space station are described as well as tended industrial and polar platforms. The mass properties that are the basis for costing are summarized. User friendly attributes (interfaces, resources, and facilities) are identified for commercial; science and applications; industrial park; international participation; national security; and the external tank option. Configuration alternates studied to determine a baseline are examined. Commonality for clustered 3-man and 9-man stations are considered as well as the use of tethered platforms. Requirements are indicated for electrical, communication and tracking; data management Subsystem requirements for electrical, data management, communication and tracking, environment control/life support system; and guidance navigation and control subsystems are identified.

Space Tug systems study. Volume 2: Compendium

NASA Technical Reports Server (NTRS)

1974-01-01

Possible storable propellant configurations and program plans are evaluated for the space tug. Alternatives examined include: use of existing expendable stages modified for use with shuttle, followed by a space tug at a later date; use of a modified growth version of existing expendable stages for greater performance and potential reuse, followed by a space tug at a later date; use of a low development cost, reusable, interim space tug available at shuttle initial operational capability (IOC) that could be evolved to greater system capabilities at a later date; and use a direct developed tug with maximum potential to be available at some specified time after space shuttle IOC. The capability options were narrowed down to three final options for detailed program definition.

Better Assessment of Operational Suitability. Volume 2. Case Studies

DTIC Science & Technology

1992-01-01

August to 25 October 1988. Although declared operationally effective and suitable by OTEA, a Corrective Action Plan (CAP) was instituted on 5 December 1988...to correct performance deficiencies encountered in FOT&E. The option year 3 procureiaent was exercised on 8 December 1988. An OTEA assessment of the...Hughes developed and tested airframe design modifications to correct deficiencies noted in DT POT I, to improve flight handling characteristics, and to

Space Station crew safety alternatives study. Volume 5: Space Station safety plan

NASA Technical Reports Server (NTRS)

Mead, G. H.; Peercy, R. L., Jr.; Raasch, R. F.

1985-01-01

The Space Station Safety Plan has been prepared as an adjunct to the subject contract final report, suggesting the tasks and implementation procedures to ensure that threats are addressed and resolution strategy options identified and incorporated into the space station program. The safety program's approach is to realize minimum risk exposure without levying undue design and operational constraints. Safety objectives and risk acceptances are discussed.

Artificial lightweight aggregates as utilization for future ashes - A case study.

PubMed

Sarabèr, Angelo; Overhof, Robert; Green, Terry; Pels, Jan

2012-01-01

In the future, more electricity in the Netherlands will be produced using coal with co-combustion. Due to this, the generated annual ash volume will increase and the chemical composition will be influenced. One of the options for utilization if present markets are saturated and for use of fly ashes with different compositions, is as raw material for lightweight aggregates. This was selected as one of the best utilizations options regarding potential ash volume to be applied, environmental aspects and status of technology. Because of this, a study has been performed to assess the potential utilization of fly ash for the production of lightweight aggregate. Lightweight aggregate has been produced in a laboratory scale rotary kiln. The raw material consisted of class F fly ash with high free lime content. An addition of 8% clay was necessary to get green pellets with sufficient green strength. The basic properties of the produced lightweight aggregate and its behaviour in concrete have been investigated. The concrete has a good compressive strength and its leaching behaviour meets the most stringent requirements of Dutch environmental regulations. The carbon foot print of concrete will be negatively influenced if only the concrete itself is taken into account, but the reduction of the volume weight has advantages regarding design, transport emissions and isolation properties which may counteract this. In the Dutch situation the operational costs are higher than expected potential selling price for the LWA, which implies that the gate fee for the fly ash is negative. Copyright © 2011 Elsevier Ltd. All rights reserved.

42 CFR 413.314 - Determining payment amounts: Routine per diem rate.

Code of Federal Regulations, 2013 CFR

2013-10-01

... RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost Reporting Periods...

42 CFR 413.314 - Determining payment amounts: Routine per diem rate.

Code of Federal Regulations, 2010 CFR

2010-10-01

... RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR SKILLED NURSING FACILITIES Prospectively Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost Reporting Periods...

A Coordinated and Comprehensive School-Based Career Placement Model: Volume III of a Research Project to Develop a Coordinated Comprehensive Placement System.

ERIC Educational Resources Information Center

Wisconsin Univ., Madison. Center for Studies in Vocational and Technical Education.

Volume 3 presents a descriptive outline of the Wisconsin school-based career placement model. The two major objectives for the model are: (1) to maximize the individual student's competencies for independent career functioning and (2) to maximize the availability of career placement options. For orderly transition, each student must receive the…

[Therapy options for blind microphthalmos and clinical anophthalmos].

PubMed

Schittkowski, M P

2012-11-01

Children suffering from congenital anophthalmos (absence of eyes) or blind microphthalmos (eyes too small without light perception) show significant smaller eyelids, conjunctival sacs and orbital volume due to the lack of intrauterine growth stimulus. Highly hydrophilic osmotic expanders allow prostheses to be fitted in the first year of life to compensate for the volume deficit and the substantial aesthetic disadvantages and to stimulate lid development.

ASDIR-II. Volume II. Program Description

DTIC Science & Technology

1975-01-01

in ASDIR. INPUT: Engine description, gas properties and case definition (See ASDIR-II, Volume I, User’s Manual). OIWPUT: Primarily the information...conditions Special surface cooling flow conditions Exhaust system surface properties The predictions provided by the progi un for the combination of a...nonattenuated by the atmosphere Optional exhaust system information which can be requested from the program is: Internal fluid flow properties Surface

Proceedings of the American power conference: Volume 59-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

McBride, A.E.

1997-07-01

This is Volume 59-1 of the proceedings of the American Power Conference, 1997. The contents include environmental protection; regulatory compliance and permitting; convergence of electric and gas industries; renewable/wind energy; improving operations and maintenance; globalization of renewable, generation, and distribution technologies; diagnostics; battery reliability; access to power transmission facilities; software for competitive decision making and operation; transmission and distribution; and nuclear operations and options.

Space Station crew safety alternatives study. Volume 4: Appendices

NASA Technical Reports Server (NTRS)

Peercy, R. L., Jr.; Raasch, R. F.; Rockoff, L. A.

1985-01-01

The scope of this study considered the first 15 years of accumulated space station concepts for Initial Operational Capability (10C) during the early 1990's. Twenty-five threats to the space station are identified and selected threats addressed as impacting safety criteria, escape and rescue, and human factors safety concerns. Of the 25 threats identified, eight are discussed including strategy options for threat control: fire, biological or toxic contamination, injury/illness, explosion, loss of pressurization, radiation, meteoroid penetration and debris.

A novel, volumizing cosmetic formulation significantly improves the appearance of target Glabellar lines, nasolabial folds, and crow's feet in a double-blind, vehicle-controlled clinical trial.

PubMed

Farris, Patricia K; Edison, Brenda L; Weinkauf, Ronni L; Green, Barbara A

2014-01-01

Facial lines and wrinkles are caused by many factors including constant exposure to external elements, such as UV rays, as well as the dynamic nature of facial expression. Many cosmetic products and procedures provide global improvement to aging skin, whereas injectable therapies are frequently utilized to diminish specific, target wrinkles. Despite their broad availability, some patients are unwilling to undergo injectables and would benefit from an effective topical option. A noninvasive option to volumize target wrinkle areas could also extend benefits of commonly used cosmetic anti-aging products. To this end, a two-step formulation containing the novel, cosmetic anti-aging ingredient, N-acetyl tyrosinamide, was developed for use on targeted wrinkle areas. The tolerability and efficacy of the serum plus cream were tested for 16 weeks in women with moderate facial photodamage on predetermined wrinkle areas (glabellar lines, nasolabial folds, under eye lines, and lateral canthal (crow's feet) wrinkles) in a single-center, randomized, double-blind, vehicle-controlled, clinical trial. Seventy women (47 Active group, 23 Vehicle group) completed the study. Digital photography, clinical grading, ultrasound and self-assessment scores confirmed improvement to wrinkle areas. The topical cosmetic formulation was statistically superior (P<0.05) to its vehicle in visually improving nasolabial folds, glabellar lines, crow's feet, and under eye wrinkles and in reducing pinch recoil time. Both the test formulation and its vehicle were tolerated well. The novel, two-step cosmetic formulation reduced the appearance of wrinkles and increased skin elasticity thus providing an effective anti-aging option for target wrinkle areas. This study suggests that in addition to its use as monotherapy for reducing targeted lines and wrinkles this cosmetic formulation may be also serve as an adjuvant to injectable therapies.

Volume and intensity of Medicare physicians' services: An overview

PubMed Central

Kay, Terrence L.

1990-01-01

From 1978 to 1987, Medicare spending for physicians' services increased at annual compound rates of 16 percent, far exceeding increases expected based on inflation and increases in beneficiaries. As a result, Medicare spending for Part B physicians' services has attracted considerable attention. This article contains an overview of expenditure trends for Part B physicians' services, a summary of recent research findings on issues related to volume and intensity of physicians' services, and a discussion of options for controlling volume and intensity. The possible impact of the recently enacted relative-value-based fee schedule on volume and intensity of services is discussed briefly. PMID:10113398

Nonsurgical Rejuvenation of the Eyelids with Hyaluronic Acid Gel Injections

PubMed Central

Lee, Seongmu; Yen, Michael T.

2017-01-01

There has been an increased recognition for the role volume deflation plays in the aging periorbital area, and as such, rejuvenation strategies to augment and restore volume have developed and evolved. Hyaluronic acid fillers provide an efficient option for volume augmentation with good efficacy, longevity, and safety. An understanding of the changes in the upper and lower periocular area due to aging, the meticulous identification of focal hollows, and the precise delivery of filler to these areas can smooth contours and restore a rejuvenated periorbital area. PMID:28255285

Orbiting deep space relay station. Volume 3: Implementation plan

NASA Technical Reports Server (NTRS)

Hunter, J. A.

1979-01-01

An implementation plan for the Orbiting Deep Space Relay Station (ODSRS) is described. A comparison of ODSRS life cycle costs to other configuration options meeting future communication requirements is presented.

Space industrialization. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1978-01-01

Potential goals for space industrialization were identified, and evolutionary program options for the realization of those goals were developed and assessed. Program support demands were defined, and recommendations were made in relation to program implementation.

Satellite services system analysis study. Volume 4: Service equipment concepts

NASA Technical Reports Server (NTRS)

1981-01-01

Payload deployment equipment is discussed, including payload separation, retention structures, the remote manipulator system, tilt tables, the payload installation and deployment aid, the handling and positioning aid, and spin tables. Close proximity retrieval, and on-orbit servicing equipment is discussed. Backup and contingency equipment is also discussed. Delivery and retrieval of high-energy payloads are considered. Earth return equipment, the aft flight deck, optional, and advanced equipment are also discussed.

Study on utilization of advanced composites in commercial aircraft wing structures, volume 2

NASA Technical Reports Server (NTRS)

Sakata, I. F.; Ostrom, R. B.

1978-01-01

A plan is defined for a composite wing development effort which will assist commercial transport manufacturers in reaching a level of technology readiness where the utilization of composite wing structure is a cost competitive option for a new aircraft production plan. The recommended development effort consists of two programs: a joint government/industry material development program and a wing structure development program. Both programs are described in detail.

Space station needs, attributes and architectural options study. Volume 7-2: Data book. Commercial missions

NASA Technical Reports Server (NTRS)

1983-01-01

The history of NASA's materials processing in space activities is reviewed. Market projections, support requirements, orbital operations issues, cost estimates and candidate systems (orbiter sortie flight, orbiter serviced free flyer, space station, space station serviced free flyer) for the space production of semiconductor crystals are examined. Mission requirements are identified for materials processing, communications missions, bioprocessing, and for transferring aviation maintenance training technology to spacecraft.

Future space transportation systems analysis study. Phase 1 extension: Transportation systems reference data, volume 2

NASA Technical Reports Server (NTRS)

1975-01-01

Transportation mass requirements are developed for various mission and transportation modes based on vehicle systems sized to fit the exact needs of each mission. The parametric data used to derive the mass requirements for each mission and transportation mode are presented to enable accommodation of possible changes in mode options or payload definitions. The vehicle sizing and functional requirements used to derive the parametric data are described.

Space Station Systems Analysis Study. Volume 2: Program review report

NASA Technical Reports Server (NTRS)

1977-01-01

Major growth options for tended and manned space stations in LEO and GEO are examined including increased orbiter augmentation and habitation requirements. Approaches for providing power supplies, construction aids needed to assemble support platforms, transportation system constraints, and the hardware required for various missions categories are defined. Subsystem requirements are analyzed for structure; flight control; power generation and storage; avionic; life support systems; personnel provisions; and environmental control. Tradeoffs are considered.

New Stimulation Strategy to Improve the Bladder Function in Paraplegics: Chronic Experiments in Dogs

DTIC Science & Technology

2001-10-25

urinary system [4]. More recently, neurostimulation and neuromodulation of the sacral nerve root seems to be one of the most promising options to enhance...day. Expelled and residual urine volumes were measured. Also the applied parameters for the continuous low frequency / low amplitude neuromodulation ...VCUG) with neurostimulation was carried out after IVU study. Low-frequency only stimulation During the 7th month, daily stimulations were performed

Space station WP-04 power system. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Hallinan, G. J.

1987-01-01

Major study activities and results of the phase B study contract for the preliminary design of the space station Electrical Power System (EPS) are summarized. The areas addressed include the general system design, man-tended option, automation and robotics, evolutionary growth, software development environment, advanced development, customer accommodations, operations planning, product assurance, and design and development phase planning. The EPS consists of a combination photovoltaic and solar dynamic power generation subsystem and a power management and distribution (PMAD) subsystem. System trade studies and costing activities are also summarized.

Bioresearch Module Design Definition and Space Shuttle Vehicle Integration Study. Volume 1: Basic Report

NASA Technical Reports Server (NTRS)

Lang, A. L., Jr.

1971-01-01

Preliminary designs of the Bioexplorer spacecraft, developed in an earlier study program, are analyzed and updated to conform to a new specification which includes use of both the Scout and the space shuttle vehicle for launch. The updated spacecraft is referred to as bioresearch module. It is capable of supporting a variety of small biological experiments in near-earth and highly elliptical earth orbits. The baseline spacecraft design is compatible with the Scout launch vehicle. Inboard profile drawings, weight statements, interface drawings, and spacecraft parts and aerospace ground equipment lists are provided to document the design. The baseline design was analyzed to determine the design and cost impact of a set of optional features. These include reduced experiment power and thermal load, addition of an experiment television monitor, and replacement of VHF with S-band communications. The impact of these options on power required, weight change and cost is defined.

Preliminary subsystem designs for the Assured Crew Return Vehicle (ACRV), volume 1

NASA Technical Reports Server (NTRS)

1990-01-01

A series of design studies is presented concerning the Assured Crew Return Vehicle (ACRV) for Space Station Freedom. Four alternate designs are presented for the ACRV braking and landing system. Options presented include: ballistic and lifting body reentries; the use of high-lift, high-payload aerodynamic decelerators, as well as conventional parachutes; landing systems designed for water landings, land landings, or both; and an aerial recovery system. All four design options presented combine some or all of the above attributes, and all meet performance requirements established by the ACRV Program Office. Two studies of ACRV growth options are also presented. Use of the ACRV or a similarly designed vehicle in several roles for possible future space missions is discussed, along with the required changes to a basic ACRV to allow it to perform these missions optimally. The outcome of these studies is a set of recommendations to the ACRV Program Office describing the vehicle characteristics of the basic ACRV which lend themselves most readily to be adapted for use in other missions. Finally, the impacts on the design of the ACRV due to its role as a medical emergency vehicle were studied and are presented. The use of the ACRV in this manner will impact its shape, internal configuration, and equipment.

Application of ion chromatography in clinical studies and pharmaceutical industry.

PubMed

Michalski, Rajmund

2014-01-01

Ion chromatography is a well-established regulatory method for analyzing anions and cations in environmental, food and many other samples. It offers an enormous range of possibilities for selecting stationary and mobile phases. Additionally, it usually helps to solve various separation problems, particularly when it is combined with different detection techniques. Ion chromatography can also be used to determine many ions and substances in clinical and pharmaceutical samples. It provides: availability of high capacity stationary phases and sensitive detectors; simple sample preparation; avoidance of hazardous chemicals; decreased sample volumes; flexible reaction options on a changing sample matrix to be analyzed; or the option to operate a fully-automated system. This paper provides a short review of the ion chromatography applications for determining different inorganic and organic substances in clinical and pharmaceutical samples.

Stereotactic Radiosurgery for Intracranial Ependymomas: An International Multicenter Study.

PubMed

Kano, Hideyuki; Su, Yan-Hua; Wu, Hsiu-Mei; Simonova, Gabriela; Liscak, Roman; Cohen-Inbar, Or; Sheehan, Jason P; Meola, Antonio; Sharma, Mayur; Barnett, Gene H; Mathieu, David; Vasas, Lucas T; Kaufmann, Anthony M; Jacobs, Rachel C; Lunsford, L Dade

2018-03-28

Stereotactic radiosurgery (SRS) is a potentially important option for intracranial ependymoma patients. To analyze the outcomes of intracranial ependymoma patients who underwent SRS as a part of multimodality management. Seven centers participating in the International Gamma Knife Research Foundation identified 89 intracranial ependymoma patients who underwent SRS (113 tumors). The median patient age was 16.3 yr (2.9-80). All patients underwent previous surgical resection and radiation therapy (RT) of their ependymomas and 40 underwent previous chemotherapy. Grade 2 ependymomas were present in 42 patients (52 tumors) and grade 3 ependymomas in 48 patients (61 tumors). The median tumor volume was 2.2 cc (0.03-36.8) and the median margin dose was 15 Gy (9-24). Forty-seven (53%) patients were alive and 42 (47%) patients died at the last follow-up. The overall survival after SRS was 86% at 1 yr, 50% at 3 yr, and 44% at 5 yr. Smaller total tumor volume was associated with longer overall survival (P = .006). Twenty-two patients (grade 2: n = 9, grade 3: n = 13) developed additional recurrent ependymomas in the craniospinal axis. The progression-free survival after SRS was 71% at 1 yr, 56% at 3 yr, and 48% at 5 yr. Adult age, female sex, and smaller tumor volume indicated significantly better progression-free survival. Symptomatic adverse radiation effects were seen in 7 patients (8%). SRS provides another management option for residual or recurrent progressive intracranial ependymoma patients who have failed initial surgery and RT.

77 FR 518 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-05

... two monthly login IDs (so, $600 for one), or a fee of $2,400 for a higher- volume user.\\6\\ The NASDAQ... a minimum of two monthly login IDs and does not have a separate fee for a higher-volume user. See.... 78f(b)(4). The proposed changes to increase the fees assessed for CMI Login IDs and FIX Login IDs are...

A mathematical model for Vertical Attitude Takeoff and Landing (VATOL) aircraft simulation. Volume 3: User's manual for VATOL simulation program

NASA Technical Reports Server (NTRS)

Fortenbaugh, R. L.

1980-01-01

Instructions for using Vertical Attitude Takeoff and Landing Aircraft Simulation (VATLAS), the digital simulation program for application to vertical attitude takeoff and landing (VATOL) aircraft developed for installation on the NASA Ames CDC 7600 computer system are described. The framework for VATLAS is the Off-Line Simulation (OLSIM) routine. The OLSIM routine provides a flexible framework and standardized modules which facilitate the development of off-line aircraft simulations. OLSIM runs under the control of VTOLTH, the main program, which calls the proper modules for executing user specified options. These options include trim, stability derivative calculation, time history generation, and various input-output options.

The MHOST finite element program: 3-D inelastic analysis methods for hot section components. Volume 2: User's manual

NASA Technical Reports Server (NTRS)

Nakazawa, Shohei

1989-01-01

The user options available for running the MHOST finite element analysis package is described. MHOST is a solid and structural analysis program based on the mixed finite element technology, and is specifically designed for 3-D inelastic analysis. A family of 2- and 3-D continuum elements along with beam and shell structural elements can be utilized, many options are available in the constitutive equation library, the solution algorithms and the analysis capabilities. The outline of solution algorithms is discussed along with the data input and output, analysis options including the user subroutines and the definition of the finite elements implemented in the program package.

Satellite power systems (SPS) concept definition study. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Hanley, G. M.

1980-01-01

System definition studies resulted in a further definition of the reference system using gallium arsenide solar arrays, analysis of alternative subsystem options for the reference concept, preliminary solid state microwave concept studies, and an environmental analysis of laser transmission systems. The special emphasis studies concentrated on satellite construction, satellite construction base definition, satellite construction base construction, and rectenna construction. Major emphasis in the transportation studies was put on definition of a two stage parallel burn, vertical takeoff/horizontal landing concept. The electric orbit transfer vehicle was defined in greater detail. Program definition included cost analyses and schedule definition.

Spacelab user implementation assessment study (software requirements analysis). Volume 1: Executive study

NASA Technical Reports Server (NTRS)

1976-01-01

The primary objective of this study was to develop an integrated approach for the development, implementation, and utilization of all software that is required to efficiently and cost-effectively support advanced technology laboratory flight and ground operations. It was recognized that certain aspects of the operations would be mandatory computerized services; computerization of other aspects would be optional. Thus, the analyses encompassed not only alternate computer utilization and implementations but trade studies of the programmatic effects of non-computerized versus computerized approaches to the operations. A general overview of the study is presented.

Space station needs, attributes and architectural options. Volume 4, attachment 1: Task 2 and 3 mission implementation and cost

NASA Technical Reports Server (NTRS)

1983-01-01

Mission scenario analysis and architectural concepts, alternative systems concepts, mission operations and architectural development, architectural analysis trades, evolution, configuration, and technology development are assessed.

Technologies that complement congestion pricing : a primer.

DOT National Transportation Integrated Search

2008-10-01

The purpose of this volume is to consider the technology options that are available to complement congestion-pricing approaches. This primer explores how technology broadens the success for congestion pricing by supporting the traveler's decision to ...

DDN (Defense Data Network) Protocol Handbook. Volume 2. DARPA Internet Protocols

DTIC Science & Technology

1985-12-01

header padding is used to ensure that the internet header ends on a 32 bit boundary. The padding is zero . 3.2. Discussion The implementation of a... zeros . The first of these would be interpreted as the end-of-options option, and the remainder as internet header padding , Every internet module must...several octets in length. The internet header Padding field is used to ensure that the data begins on 32 bit word boundary. The padding is zero

Spacecraft/Environment Interactions CAE Tool. Volume 1. Users Manual

DTIC Science & Technology

1988-01-01

aproe fo ubii-: K Arr A /- - " ,-’- .71 . IX, Iy- ,, A A GAUDE’, LT COL, USAF FOR -1E COMltaNDE > (SignturJ; RITA C. SAGCALYN Division Director Thi...report hay boen reviwed by the ESD Public Affairs Office (PA) and is relea-able to the ,.rAtional Techni.a1 Infor-,ation Service (NTIS). Qualified...Parts. Other Options TlY- procedure described above is the simplest method , r ,. files, but excludes several options provided by . K \\11. 5000. If the

Right Sizing the Force: Restructuring the Marine Light Attack Helicopter (HML/A) Squadron to Better Meet the Emerging Threat

DTIC Science & Technology

2009-04-29

visual coverage armed with responsive, high volume offensive or defensive door mounted machine guns and nearly 3600 weapons coverage. In addition, a fixed...forward gun option and forward firing rocket capacity substantially expand firepower options. Team this crew and machine with the world’s premiere...escort. 1 Headquarters, U. S. Marine Corps, Vision & Strategy 2025, (Washington, DC: Headquarters, U.S. Marine Corps, June 18, 2008), 9. 2 Scott Atwood

Efficient voxel navigation for proton therapy dose calculation in TOPAS and Geant4

NASA Astrophysics Data System (ADS)

Schümann, J.; Paganetti, H.; Shin, J.; Faddegon, B.; Perl, J.

2012-06-01

A key task within all Monte Carlo particle transport codes is ‘navigation’, the calculation to determine at each particle step what volume the particle may be leaving and what volume the particle may be entering. Navigation should be optimized to the specific geometry at hand. For patient dose calculation, this geometry generally involves voxelized computed tomography (CT) data. We investigated the efficiency of navigation algorithms on currently available voxel geometry parameterizations in the Monte Carlo simulation package Geant4: G4VPVParameterisation, G4VNestedParameterisation and G4PhantomParameterisation, the last with and without boundary skipping, a method where neighboring voxels with the same Hounsfield unit are combined into one larger voxel. A fourth parameterization approach (MGHParameterization), developed in-house before the latter two parameterizations became available in Geant4, was also included in this study. All simulations were performed using TOPAS, a tool for particle simulations layered on top of Geant4. Runtime comparisons were made on three distinct patient CT data sets: a head and neck, a liver and a prostate patient. We included an additional version of these three patients where all voxels, including the air voxels outside of the patient, were uniformly set to water in the runtime study. The G4VPVParameterisation offers two optimization options. One option has a 60-150 times slower simulation speed. The other is compatible in speed but requires 15-19 times more memory compared to the other parameterizations. We found the average CPU time used for the simulation relative to G4VNestedParameterisation to be 1.014 for G4PhantomParameterisation without boundary skipping and 1.015 for MGHParameterization. The average runtime ratio for G4PhantomParameterisation with and without boundary skipping for our heterogeneous data was equal to 0.97: 1. The calculated dose distributions agreed with the reference distribution for all but the G4PhantomParameterisation with boundary skipping for the head and neck patient. The maximum memory usage ranged from 0.8 to 1.8 GB depending on the CT volume independent of parameterizations, except for the 15-19 times greater memory usage with the G4VPVParameterisation when using the option with a higher simulation speed. The G4VNestedParameterisation was selected as the preferred choice for the patient geometries and treatment plans studied.

Laundry Study for a Lunar Outpost

NASA Technical Reports Server (NTRS)

Ewert, Michael; Jeng, Frank

2009-01-01

In support of the Constellation Program, which will return humans to the moon and establish an Outpost, NASA has conducted an analysis of crew clothing and laundry options. Single-use or "disposable" clothing has been used from Apollo until International Space Station (ISS) missions, meaning that clothes were worn for the whole mission or thrown away when they became too dirty to wear any longer. This is justified for short duration missions; however, as the Constellation mission will last much longer and each individual Outpost mission is expected to last up to 180 days, mission goals and launch penalties for mass and volume may lead to a different conclusion. Furthermore, the habitat atmosphere pressure and therefore oxygen volume percentage will be different from ISS or Shuttle. Almost daily EVA sorties will be a norm during Outpost exploration missions. All of these factors will have impacts on selection of crew clothing and laundry options for Outpost missions. Mass and volume estimates for disposable crew clothing have been shown as a major penalty in long-duration manned space exploration missions in previous analyses. Assuming disposable clothing like ISS, Equivalent System Mass (ESM) of crew clothing and hygiene towels was estimated to be 11,000 kg or about 11% of total life support system ESM for a 10-year Lunar Outpost mission with 4 crew members. Ways to reduce this clothing penalty, which are discussed in this paper, include: a) Reduce clothing supply rate through using clothes made of advanced fabrics; b) Reduce daily usage rate by extending its use duration before disposing; and c) Use laundry and reusable clothing. The report summarizes recent research efforts in advanced clothing, proposed clothing supply rates for Exploration missions, results of a trade-off study between disposable clothing and laundry, and conclusions and suggestions for Constellation Program clothing.

Space Station crew safety alternatives study. Volume 2: Threat development

NASA Technical Reports Server (NTRS)

Raasch, R. F.; Peercy, R. L., Jr.; Rockoff, L. A.

1985-01-01

The first 15 years of accumulated space station concepts for initial operational capability (IOC) during the early 1990's were considered. Twenty-five threats to the space station are identified and selected threats addressed as impacting safety criteria, escape and rescue, and human factors safety concerns. Of the 25 threats identified, eight are discussed including strategy options for threat control: fire, biological or toxic contamination, injury/illness, explosion, loss of pressurization, radiation, meteoroid penetration, and debris.

Space station crew safety alternatives study, volume 1

NASA Technical Reports Server (NTRS)

Peercy, R. L., Jr.; Raasch, R. F.; Rockoff, L. A.

1985-01-01

The first 15 years of accumulated space station concepts for initial operational capability (IOC) during the early 1990's were considered. Twenty-five threats to the space station are identified and selected threats addressed as impacting safety criteria, escape and rescue, and human factors safety concerns. Of the 25 threats identified, eight are discussed including strategy options for threat control: fire, biological or toxic contamination, injury/illness, explosion, loss of pressurization, radiation, meteoroid penetration and debris.

Thirteenth Annual Acquisition Research Symposium. Acquisition Research: Creating Synergy for Informed Change. Volume 1

DTIC Science & Technology

2016-04-30

renewable energy projects with a focus on novel onshore/offshore and small/large scale wind turbine designs for expanding their operational range and...ROA to estimate the values of maintenance options created by the implementation of PHM in wind turbines . When an RUL is predicted for a subsystem...predicted for the system. The section titled Example— Wind Turbine With an Outcome-Based Contract presents a case study for a PHM enabled wind

Production of Jet Fuels from Coal Derived Liquids. Volume 10. Jet Fuels Production By-Products, Utility and Sulfur Emissions Control Integration Study

DTIC Science & Technology

1989-06-01

FLUE GAS DESULFURIZATION EVALUATION A-1/A-2 3-1. 3 BOILER STACK EMISSION CONTROL WITH...Appendices A - BACT Flue Gas Desulfurization Evaluation B - BACT Off- Gas Refrigeration Evaluation v LIST OF FIGURES Figure Page 1. Material Balance for...2. Desulfurize the flue gases from the Riley boilers when firing with high sulfur oils or lignite. Options in this category include commercial wet

Specialized Study Options U.S.A., 1986-1988. A Guide to Short-Term Educational Programs in the United States for Foreign Nationals. Volume 1: Technical Education. Second Edition.

ERIC Educational Resources Information Center

Howard, Edrice, Ed.

Information is provided on over 1,000 short-term programs offered by United States universities, trade and technical schools, and other organizations that are open to or designed for non-U.S. students. The programs, which range from 2 weeks to 1 year in length, require only a high school diploma as a prerequisite for enrollment. The programs are…

Option contracts for allocating water in inter-basin transfers: the case of the Tagus-Segura Transfer in Spain

NASA Astrophysics Data System (ADS)

Rey, Dolores; Garrido, Alberto; Calatraba, Javier

2014-05-01

Users in the Mediterranean region face significant water supply risks. Water markets mechanisms can provide flexibility to water systems run in tight situations. The largest water infrastructure in the Iberian Peninsula connects the Segura and Tagus Basins. Stakeholders and politicians in the Tagus Basin have asked that water transfers between the two basins be eventually phased out. The need to increase the statutory minimum environmental flow in the middle Tagus and to meet new urban demands is going to result in a redefinition of the Transfer's management rules, leading to a reduction in the transferable volumes. To minimise the consequences of such restrictions to irrigators in the Segura Basin who depend on the transferred volumes, we propose the establishment of water option contracts between both basins that represents an institutional innovation with respect to previous inter-basin spot market experiences. Based on the draft of the new Tagus Basin Plan, we propose both a modification of the Transfer's management rule and an innovative inter-basin option contract. The main goal of the paper is to define this contract and evaluate it with respect to non-market scenarios. We also assess the resulting impact on environmental flows in the Tagus River and water availability for users in the Segura Basin, together with the economic impacts of such contract on both basins. Our results show that the proposed option contract would reduce the impact of a change in the transfer's management rule, and reduce the supply risks of the recipient area. Keywords: environmental flow, inter-basin transfer, option contracts, Tagus-Segura, water markets, water supply reliability.

Joint Peru/United States report on Peru/United States cooperative energy assessment. Volume 1. Executive summary, main report and appendices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1979-08-01

In 1978, the US and Peru conducted a comprehensive assessment of Peru's energy resources, needs, and uses and developed several alternative energy strategies that utilize the available resources to meet their energy requirements. This Volume I reports the findings of the assessment and contains the executive summary, the main report, and five appendices of information that support the integrated energy supply and demand analysis. The following chapters are included: The Energy Situation in Peru (economic context and background, energy resources and production, energy consumption patterns); Reference Supply and Demand Projection (approach, procedures, and assumptions; economic projections; energy demand and supplymore » projections; supply/demand integration; uncertainties); and The Development of Strategies and Options (the analysis of options; strategies; increased use of renewables, hydropower, coal; increased energy efficiency; and financial analysis of strategies).« less

The Evolving Market Structure of the U.S. Residential Solar PV Installation Industry, 2000-2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

OShaughnessy, Eric J.

This study uses data on over 900,000 solar PV installations to summarize the evolving market structure of the U.S. residential solar PV installation industry. Over 8,000 companies have installed residential PV systems in the United States. The vast majority of these installers are small local companies. At the same time, a subset of national-scale high-volume PV installation companies hold high market shares. This study examines the factors behind these trends in market concentration, including the role of customer financing options.

Feasibility study for the Swaziland/Mozambique interconnector. EPC specifications. Export trade information

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-11-01

This study, conducted by Black & Veatch, was funded by the U.S. Trade and Development Agency. The report, produced for the Ministry of National Resources, Energy and Environment (MNRE) of Swaziland, determines the least cost capacity expansion option to meet the future power demand and system reliability criteria of Swaziland, with particular emphasis on the proposed Interconnector between Swaziland and Mozambique. Volume 3 contains EPC Specifications and is divided into the following divisions: (1) Commercial; (2) General Technical Requirements; (3) Transmission Line Technical Requirements; (4) Substation Technical Requirements; (5) Specifications.

Tactical radar technology study. Volume 1: Executive summary

NASA Astrophysics Data System (ADS)

Rosien, R.; Cardone, L.; Hammers, D.; Klein, A.; Nozawa, E.

1980-03-01

This report presents results of a study to identify new technology required to provide advanced multi-threat performance capabilities in future tactical surveillance radar designs. A baseline design with optional subsystem characteristics has been synthesized to provide both functional and operational survivability in a dynamic and hostile situation postulated for the post 1985 time frame. Comparisons have been made of available technology with that required by the new baseline design to identify new technology requirements. Recommendations are presented for critical new technology programs including estimates of technical risks, costs and required development time.

Reusable Agena study. Volume 2: Technical

NASA Technical Reports Server (NTRS)

Carter, W. K.; Piper, J. E.; Douglass, D. A.; Waller, E. W.; Hopkins, C. V.; Fitzgerald, E. T.; Sagawa, S. S.; Carter, S. A.; Jensen, H. L.

1974-01-01

The application of the existing Agena vehicle as a reusable upper stage for the space shuttle is discussed. The primary objective of the study is to define those changes to the Agena required for it to function in the reusable mode in the 100 percent capture of the NASA-DOD mission model. This 100 percent capture is achieved without use of kick motors or stages by simply increasing the Agena propellant load by using optional strap-on-tanks. The required shuttle support equipment, launch and flight operations techniques, development program, and cost package are also defined.

Ejection fraction in myocardial perfusion imaging assessed with a dynamic phantom: comparison between IQ-SPECT and LEHR.

PubMed

Hippeläinen, Eero; Mäkelä, Teemu; Kaasalainen, Touko; Kaleva, Erna

2017-12-01

Developments in single photon emission tomography instrumentation and reconstruction methods present a potential for decreasing acquisition times. One of such recent options for myocardial perfusion imaging (MPI) is IQ-SPECT. This study was motivated by the inconsistency in the reported ejection fraction (EF) and left ventricular (LV) volume results between IQ-SPECT and more conventional low-energy high-resolution (LEHR) collimation protocols. IQ-SPECT and LEHR quantitative results were compared while the equivalent number of iterations (EI) was varied. The end-diastolic (EDV) and end-systolic volumes (ESV) and the derived EF values were investigated. A dynamic heart phantom was used to produce repeatable ESVs, EDVs and EFs. Phantom performance was verified by comparing the set EF values to those measured from a gated multi-slice X-ray computed tomography (CT) scan (EF True ). The phantom with an EF setting of 45, 55, 65 and 70% was imaged with both IQ-SPECT and LEHR protocols. The data were reconstructed with different EI, and two commonly used clinical myocardium delineation software were used to evaluate the LV volumes. The CT verification showed that the phantom EF settings were repeatable and accurate with the EF True being within 1% point from the manufacture's nominal value. Depending on EI both MPI protocols can be made to produce correct EF estimates, but IQ-SPECT protocol produced on average 41 and 42% smaller EDV and ESV when compared to the phantom's volumes, while LEHR protocol underestimated volumes by 24 and 21%, respectively. The volume results were largely similar between the delineation methods used. The reconstruction parameters can greatly affect the volume estimates obtained from perfusion studies. IQ-SPECT produces systematically smaller LV volumes than the conventional LEHR MPI protocol. The volume estimates are also software dependent.

Joint Egypt/United States report on Egypt/United States cooperative energy assessment. Volume 1 of 5 Vols. Executive summary, main report and appendices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1979-04-01

The International Energy Assessment Program between Egypt and the U.S. was formulated from mid-March to mid-July, 1978. The assessment identified energy demand and supply options for Egypt that are consistent with its indigenous energy resources; assessed Egypt's ability to effectively use those options; and identified measures by which Egypt's energy-planning activities could be improved. The assessment addressed all known and potential energy supply options (oil, gas, coal, oil shale, hydroelectric, nuclear power, geothermal, solar, wind, and biomass). Using the Reference Energy System, two future energy supply/demand balances are constructed (for 1985 and the year 2000) and these are compared withmore » a historical (1975) supply/demand balance. The feasibility of each of the options is established in terms of the availability of the required resources and of the processing, conversion, transport, and utilization technology.« less

Review of biosolids management options and co-incineration of a biosolid-derived fuel.

PubMed

Roy, Murari Mohon; Dutta, Animesh; Corscadden, Kenny; Havard, Peter; Dickie, Lucas

2011-11-01

This paper reviews current biosolids management options, and identifies incineration as a promising technology. Incineration is attractive both for volume reduction and energy recovery. Reported emissions from the incineration of biosolids were compared to various regulations to identify the challenges and future direction of biosolids incineration research. Most of the gaseous and metal emissions were lower than existing regulations, or could be met by existing technologies. This paper also presents the results of an experimental study to investigate the potential use of biosolids for co-incineration with wood pellets in a conventional wood pellet stove. Pilot scale combustion tests revealed that co-incineration of 10% biosolids with 90% premium grade wood pellets resulted in successful combustion without any significant degradation of efficiency and emissions. Copyright © 2011 Elsevier Ltd. All rights reserved.

Experimental Test Concept for a Cargo Data Interchange System (CARDIS) : Volume 1. Text.

DOT National Transportation Integrated Search

1976-05-01

This report includes the recommended CARDIS experimental test system functional capabilities. It identifies the CARDIS functions that are inherent to an information exchange capability and optional systems which are required by the transportation rel...

CONTAMINANTS AND REMEDIAL OPTIONS AT PESTICIDE SITES

EPA Science Inventory

Many types of soils, sediments, and sludges are contaminated with a wide variety of pesticides. ite-specific characteristics such as volume to be treated, extent of contamination, and applicable cleanup goals differ greatly, and contaminant toxicity, migration pathways, persisten...

Experimental Test Concept for a Cargo Data Interchange System (CARDIS) : Volume 2. Appendixes.

DOT National Transportation Integrated Search

1976-05-01

This report includes the recommended CARDIS experimental test system functional capabilities. It identifies the CARDIS functions that are inherent to an information exchange capability and optional systems which are required by the transportation rel...

Current treatment options for the management of esophageal cancer

PubMed Central

Mawhinney, Mark R; Glasgow, Robert E

2012-01-01

In recent years, esophageal cancer characteristics and management options have evolved significantly. There has been a sharp increase in the frequency of esophageal adenocarcinoma and a decline in the frequency of squamous cell carcinoma. A more comprehensive understanding of prognostic factors influencing outcome has also been developed. This has led to more management options for esophageal cancer at all stages than ever before. A multidisciplinary, team approach to management in a high volume center is the preferred approach. Each patient should be individually assessed based on type of cancer, local or regional involvement, and his or her own functional status to determine an appropriate treatment regimen. This review will discuss management of esophageal cancer relative to disease progression and patient functional status. PMID:23152702

Functional Requirements of a Target Description System for Vulnerability Analysis

DTIC Science & Technology

1979-11-01

called GIFT .1,2 Together the COMGEOM description model and GIFT codes make up the BRL’s target description system. The significance of a target...and modifying target descriptions are described. 1 Lawrence W. Bain, Jr. and Mathew J. Reisinger, "The GIFT Code User Manual; Volume 1...34The GIFT Code User Manual; Volume II, The Output Options," unpublished draft of BRL report. II. UNDERLYING PHILOSOPHY The BRL has a computer

Forecasting daily passenger traffic volumes in the Moscow metro

NASA Astrophysics Data System (ADS)

Ivanov, V. V.; Osetrov, E. S.

2018-01-01

In this paper we have developed a methodology for the medium-term prediction of daily volumes of passenger traffic in the Moscow metro. It includes three options for the forecast: (1) based on artificial neural networks (ANNs), (2) singular-spectral analysis implemented in the Caterpillar-SSA package, and (3) a combination of the ANN and Caterpillar-SSA approaches. The methods and algorithms allow the mediumterm forecasting of passenger traffic flows in the Moscow metro with reasonable accuracy.

Improved Devices for Collecting Sweat for Chemical Analysis

NASA Technical Reports Server (NTRS)

Feeback, Daniel L.; Clarke, Mark S. F.

2011-01-01

Improved devices have been proposed for collecting sweat for biochemical analysis especially for determination of the concentration of Ca2+ ions in sweat as a measure of loss of Ca from bones. Unlike commercially available sweat-collection patches used previously in monitoring osteoporosis and in qualitative screening for some drugs, the proposed devices would not allow evaporation of the volatile chemical components (mostly water) of sweat. Moreover, the proposed devices would be designed to enable determination of the volumes of collected sweat. From these volumes and the quantities of Ca2+ and/or other analytes as determined by other means summarized below, one could determine the concentrations of the analytes in sweat. A device according to the proposal would be flexible and would be worn like a commercial sweat-collection patch. It would be made of molded polydimethylsiloxane (silicone rubber) or other suitable material having properties that, for the purpose of analyzing sweat, are similar to those of glass. The die for molding the silicone rubber would be fabricated by a combination of lithography and electroplating. The die would reproducibly form, in the silicone rubber, a precisely defined number of capillary channels per unit area, each channel having a precisely defined volume. Optionally, electrodes for measuring the Ca2+ content of the sweat could be incorporated into the device. The volume of sweat collected in the capillary channels of the device would be determined from (1) the amount of light or radio waves of a given wavelength absorbed by the device and (2) the known geometry of the array of capillary channels. Then, in one of two options, centrifugation would be performed to move the sweat from the capillary tubes to the region containing the electrodes, which would be used to measure the Ca2+ content by a standard technique. In the other option, centrifugation would be performed to remove the sweat from the device to make the sweat available to other analytical instruments for measuring concentrations of substances other than Ca2+.

Improved Devices for Collecting Sweat for Chemical Analysis

NASA Technical Reports Server (NTRS)

Feedback, Daniel L.; Clarke, Mark S. F.

2011-01-01

Improved devices have been proposed for collecting sweat for biochemical analysis - especially for determination of the concentration of Ca2+ ions in sweat as a measure of loss of Ca from bones. Unlike commercially available sweat-collection patches used previously in monitoring osteoporosis and in qualitative screening for some drugs, the proposed devices would not allow evaporation of the volatile chemical components (mostly water) of sweat. Moreover, the proposed devices would be designed to enable determination of the volumes of collected sweat. From these volumes and the quantities of Ca(2+) and/or other analytes as determined by other means summarized below, one could determine the concentrations of the analytes in sweat. A device according to the proposal would be flexible and would be worn like a commercial sweat-collection patch. It would be made of molded polydimethylsiloxane (silicone rubber) or other suitable material having properties that, for the purpose of analyzing sweat, are similar to those of glass. The die for molding the silicone rubber would be fabricated by a combination of lithography and electroplating. The die would reproducibly form, in the silicone rubber, a precisely defined number of capillary channels per unit area, each channel having a precisely defined volume. Optionally, electrodes for measuring the Ca(2+) content of the sweat could be incorporated into the device. The volume of sweat collected in the capillary channels of the device would be determined from (1) the amount of light or radio waves of a given wavelength absorbed by the device and (2) the known geometry of the array of capillary channels. Then, in one of two options, centrifugation would be performed to move the sweat from the capillary tubes to the region containing the electrodes, which would be used to measure the Ca(2+) content by a standard technique. In the other option, centrifugation would be performed to remove the sweat from the device to make the sweat available to other analytical instruments for measuring concentrations of substances other than Ca(2+).

Efficacy and safety of tolvaptan in heart failure patients with sustained volume overload despite the use of conventional diuretics: a phase III open-label study.

PubMed

Fukunami, Masatake; Matsuzaki, Masunori; Hori, Masatsugu; Izumi, Tohru

2011-12-01

Volume overload is a common complication associated with heart failure (HF) and is recommended to be treated with loop or thiazide diuretics. However, use of diuretics can cause serum electrolyte imbalances and diuretic resistance. Tolvaptan, a selective, oral, non-peptide vasopressin V2-receptor antagonist, offers a new option for treating volume overload in HF patients. The aim of this study was to investigate the efficacy and safety of tolvaptan in Japanese HF patients with volume overload. Fifty-one HF patients with volume overload, despite using conventional diuretics, were treated with 15 mg/day tolvaptan for 7 days. If the response was insufficient at Day 7, tolvaptan was continued for a further 7 days at either 15 mg/day or 30 mg/day. Outcomes included changes in body weight, symptoms and safety parameters. Thirty-six patients discontinued treatment within 7 days, therefore 15 patients entered the second phase of treatment. In two patients, tolvaptan was increased to 30 mg/day after 7 days. Body weight was reduced on Day 7 (-1.95 ± 1.98 kg; n = 41) and Day 14 (-2.35 ± 1.44 kg; n = 11, 15 mg/day). Symptoms of volume overload, including lower limb edema, pulmonary congestion, jugular venous distention and hepatomegaly, were improved by tolvaptan treatment for 7 or 14 days. Neither tolvaptan increased the incidence of severe or serious adverse events when administered for 7-14 days. This study confirms the efficacy and safety of 15 mg/day tolvaptan for 7-14 days in Japanese HF patients with volume overload despite conventional diuretics.

A Descriptive Study of the Temporal Patterns of Volume and Contents Change in Human Acute Burn Edema: Application in Evidence-Based Intervention and Research Design.

PubMed

Edgar, Dale W; Fear, Mark; Wood, Fiona M

2016-01-01

Edema after burn contributes significantly to burn wound depth conversion. In humans after burn injury, there is a lack of detailed understanding of the contents and temporal changes in volume of acute tissue edema. The novel findings of these studies relate to the collection of edema fluid after partial-thickness burn injury. Edema volume peaks on day 1 after burn without formal fluid resuscitation. The studies indicated that the peak was on day 2 for a resuscitated burn. In contrast, animal studies suggest that the peak of edema occurs by or before day 1 after injury. The findings confirm the pitfalls of evidence derived from animal models and assuming direct transference to humans. Postburn edema was demonstrated to be a high-protein fluid (ie, ≥10 g/L) for the duration of the inflammatory period. The presence of high-protein edema presents greater challenges to clinicians developing novel treatment options. The rate of volume change over time tapered to insignificant levels after day 4 following burn. Greater than 98% of the edema contents was fluid. However, the size of particulate matter did not preclude it passing through patent lymphatic collectors. The results indicate a necessity for urgent postburn intervention, which should incorporate the active stimulation of the lymphatic system to improve efficacy of edema removal.

Gamma Knife radiosurgery for intracranial hemangioblastoma.

PubMed

Silva, Danilo; Grabowski, Mathew M; Juthani, Rupa; Sharma, Mayur; Angelov, Lilyana; Vogelbaum, Michael A; Chao, Samuel; Suh, John; Mohammadi, Alireza; Barnett, Gene H

2016-09-01

Gamma knife radiosurgery (GKRS) has become a treatment option for intracranial hemangioblastomas, especially in patients with poor clinical status and also high-risk surgical candidates. The objective of this study was to analyze clinical outcome and tumor control rates. Retrospective chart review revealed 12 patients with a total of 20 intracranial hemangioblastomas treated with GKRS from May 1998 until December 2014. Kaplan-Meier plots were used to calculate the actuarial local tumor control rates and rate of recurrence following GKRS. Univariate analysis, including log rank test and Wilcoxon test were used on the Kaplan-Meier plots to evaluate the predictors of tumor progression. Two-tailed p value of <0.05 was considered as significant. Median follow-up was 64months (2-184). Median tumor volume pre-GKRS was 946mm(3) (79-15970), while median tumor volume post-GKRS was 356mm(3) (30-5404). Complications were seen in two patients. Tumor control rates were 100% at 1year, 90% at 3years, and 85% at 5years, using the Kaplan-Meier method. There were no statistically significant univariate predictors of progression identified, although there was a trend towards successful tumor control in solid tumors (p=0.07). GKRS is an effective and safe option for treating intracranial hemangioblastoma with favorable tumor control rates. Copyright © 2016 Elsevier Ltd. All rights reserved.

Upfront chemotherapy and subsequent resection for molecularly defined gliomas.

PubMed

Sasaki, Hikaru; Hirose, Yuichi; Yazaki, Takahito; Kitamura, Yohei; Katayama, Makoto; Kimura, Tokuhiro; Fujiwara, Hirokazu; Toda, Masahiro; Ohira, Takayuki; Yoshida, Kazunari

2015-08-01

Functional preservation is critical in glioma surgery, and the extent of resection influences survival outcome. Neoadjuvant chemotherapy is a promising option because of its potential to facilitate tumor shrinkage and maximum tumor resection. The object of this study was to assess the utility of the neoadjuvant strategy in a prospective series of gliomas with favorable molecular status. Twenty-six consecutive cases of diffuse gliomas of WHO grade II or III with either 1p19q codeletion or MGMT methylation were treated with upfront chemotherapy following maximal safe removal. In cases of incomplete initial surgery, second-look resection was intended after tumor volume decrease by chemotherapy. Among 22 evaluable cases, chemotherapy led to a median change in the sum of the product of perpendicular diameters of -35 %, and 14 out of the 22 cases (64 %) showed objective response. Second-look resection after tumor volume decrease was performed in 12 out of 19 cases of incomplete initial surgery (GTR/STR 9, removal of residual methionine PET uptake 3). The median progression-free survival among the 22 patients with grade II tumors was 57 months, with some cases showing durable progression-free survival after second-look resection. MIB-1 indices of the second-look resected tumors were lower than those of the initial tumors, and the methylation status of the MGMT gene was unchanged. Neoadjuvant chemotherapy based on molecular guidance often produces significant volume decrease of incompletely resected gliomas. Radical second-look resection is an optional advantage of upfront chemotherapy for chemosensitive gliomas compared with initial radiotherapy.

Switch-like reprogramming of gene expression after fusion of multinucleate plasmodial cells of two Physarum polycephalum sporulation mutants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walter, Pauline; Hoffmann, Xenia-Katharina; Ebeling, Britta

2013-05-24

Highlights: •We investigate reprogramming of gene expression in multinucleate single cells. •Cells of two differentiation control mutants are fused. •Fused cells proceed to alternative gene expression patterns. •The population of nuclei damps stochastic fluctuations in gene expression. •Dynamic processes of cellular reprogramming can be observed by repeated sampling of a cell. -- Abstract: Nonlinear dynamic processes involving the differential regulation of transcription factors are considered to impact the reprogramming of stem cells, germ cells, and somatic cells. Here, we fused two multinucleate plasmodial cells of Physarum polycephalum mutants defective in different sporulation control genes while being in different physiological states.more » The resulting heterokaryons established one of two significantly different expression patterns of marker genes while the plasmodial halves that were fused to each other synchronized spontaneously. Spontaneous synchronization suggests that switch-like control mechanisms spread over and finally control the entire plasmodium as a result of cytoplasmic mixing. Regulatory molecules due to the large volume of the vigorously streaming cytoplasm will define concentrations in acting on the population of nuclei and in the global setting of switches. Mixing of a large cytoplasmic volume is expected to damp stochasticity when individual nuclei deliver certain RNAs at low copy number into the cytoplasm. We conclude that spontaneous synchronization, the damping of molecular noise in gene expression by the large cytoplasmic volume, and the option to take multiple macroscopic samples from the same plasmodium provide unique options for studying the dynamics of cellular reprogramming at the single cell level.« less

The influence of jumping risk and volatility risk on TAIEX option return

NASA Astrophysics Data System (ADS)

Lee, Wei-Long; Hsieh, Ching-Tang; Huang, Jui-Chan; Wu, Tzu-Jung

2017-06-01

Due to the low profits in recent years environmental, as well as the development of financial engineering that promote the derivatives trading Volume increased. Moreover, the fastest-growing of selected right and the lack of research about option risk. This study aim to explore the relationship between the risk and reward of selected right in Taiwan index. This study focus on the pricing the jump risk of selected right in Taiwan index. Using cross-sectional data as a 12-month study period, using the iteration method to research the effects of abnormal returns, the result shows that different risk factors of fluctuations affected the abnormal returns obviously will cause risk premium as well as the jump risk which consistent with the theory of behavioral finance. However, according to traditional finance theory, contrary to the results of this study consider that higher risks should generate higher-paying as well. According this study, the investors in behavioral finance in modern financial theory is not rational, and the trading behavior is non-random, moreover, the financial market is non-efficiency. Instead, the high risk low reward.

Solar power satellite system definition study. Volume 5: Space transportation analysis, phase 3

NASA Technical Reports Server (NTRS)

1980-01-01

A small Heavy Lift Launch Vehicle (HLLV) for the Solar Power Satellites (SPS) System was analyzed. It is recommended that the small HLLV with a payload of 120 metric tons be adopted as the SPS launch vehicle. The reference HLLV, a shuttle-derived option with a payload of 400 metric tons, should serve as a backup and be examined further after initial flight experience. The electric orbit transfer vehicle should be retained as the reference orbit-to-orbit cargo system.

Study of a tracking and data acquisition system for the 1990's. Volume 1: User community characteristics

NASA Technical Reports Server (NTRS)

Mccreary, T.

1981-01-01

Projected 1990's experiments; navigation requirements and potentials; communications requirements associated with space experiments; alternative forecast options; and operational impacts on experiments are covered. A baseline of plans for the TDAS User Community, including a set of generic experiments developed to supplement existing planning for the 1990's time frame is generated. It includes extensive summaries of collected data, and a bibliography. The data are representative of inputs obtained from NASA planning sources through September 1981.

Standard spacecraft economic analysis. Volume 2: Findings and conclusions

NASA Technical Reports Server (NTRS)

Harris, E. D.; Large, J. P.

1976-01-01

The comparative program costs associated with use of various standardized spacecraft for Air Force space test program missions to be flown on the space shuttle were studied in two phases. In the first phase, a variety of procurement mixes composed of existing or programmed NASA standard spacecraft designs and an Air Force standard spacecraft design were considered. The second phase dealt with additional procurement options using an upgraded version of an existing NASA design. The results of both phases are discussed.

Technology Options to Leverage Aerospace Power in Operations Other Than Conventional War. Volume 2: Panel Reports

DTIC Science & Technology

2000-02-01

control may become more difficult . 8.0.2 The Force Management Process The concept of force management,2 as used in this study, is broader than...advances” was advantageous to the JFC. “Failure to halt an enemy invasion rapidly” would make the joint campaign “much more difficult , lengthy, and... advantage may be obtained by the timely exploitation of a new capability or vulnerability. That advantage , however, will last only a short period of

A study of space station needs, attributes and architectural options. Volume 2: Technical. Book 1: Mission requirements

NASA Technical Reports Server (NTRS)

Steinbronn, O.

1983-01-01

The following types of space missions were evaluated to determine those that require, or will be benefited materially, by a manned space station: (1) science and applications, (2) commercial, (3) technology development, (4) space operations, and (5) national security. Integrated mission requirements for man-operated and man-tended free-flying missions were addressed. A manned space station will provide major performance and economic benefits to a wide range of missions planned for the 1990s.

Operationally efficient propulsion system study (OEPSS) data book. Volume 7; Launch Operations Index (LOI) Design Features and Options

NASA Technical Reports Server (NTRS)

Ziese, James M.

1992-01-01

A design tool of figure of merit was developed that allows the operability of a propulsion system design to be measured. This Launch Operations Index (LOI) relates Operations Efficiency to System Complexity. The figure of Merit can be used by conceptual designers to compare different propulsion system designs based on their impact on launch operations. The LOI will improve the design process by making sure direct launch operations experience is a necessary feedback to the design process.

Space Operations Center system analysis study extension. Volume 4, book 2: SOC system analysis report

NASA Technical Reports Server (NTRS)

1982-01-01

The Space Operations Center (SOC) orbital space station research missions integration, crew requirements, SOC operations, and configurations are analyzed. Potential research and applications missions and their requirements are described. The capabilities of SOC are compared with user requirements. The SOC/space shuttle and shuttle-derived vehicle flight support operations and SOC orbital operations are described. Module configurations and systems options, SOC/external tank configurations, and configurations for geostationary orbits are described. Crew and systems safety configurations are summarized.

Lean coding machine. Facilities target productivity and job satisfaction with coding automation.

PubMed

Rollins, Genna

2010-07-01

Facilities are turning to coding automation to help manage the volume of electronic documentation, streamlining workflow, boosting productivity, and increasing job satisfaction. As EHR adoption increases, computer-assisted coding may become a necessity, not an option.

York Papers in Linguistics, Volume 17.

ERIC Educational Resources Information Center

Local, J. K., Ed.; Warner, A. R., Ed.

1996-01-01

These 14 articles on aspects of linguistics include the following: "Economy and Optionality: Interpretations of Subjects in Italian" (David Adger); "Collaborative Repair in EFL Classroom Talk" (Zara Iles); "A Timing Model for Fast French" (Eric Keller, Brigitte Zellner); "Another Travesty of Representation:…

Principles of Economic Rationality in Mice.

PubMed

Rivalan, Marion; Winter, York; Nachev, Vladislav

2017-12-12

Humans and non-human animals frequently violate principles of economic rationality, such as transitivity, independence of irrelevant alternatives, and regularity. The conditions that lead to these violations are not completely understood. Here we report a study on mice tested in automated home-cage setups using rewards of drinking water. Rewards differed in one of two dimensions, volume or probability. Our results suggest that mouse choice conforms to the principles of economic rationality for options that differ along a single reward dimension. A psychometric analysis of mouse choices further revealed that mice responded more strongly to differences in probability than to differences in volume, despite equivalence in return rates. This study also demonstrates the synergistic effect between the principles of economic rationality and psychophysics in making quantitative predictions about choices of healthy laboratory mice. This opens up new possibilities for the analyses of multi-dimensional choice and the use of mice with cognitive impairments that may violate economic rationality.

Clean option: An alternative strategy for Hanford Tank Waste Remediation. Volume 2, Detailed description of first example flowsheet

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swanson, J.L.

1993-09-01

Disposal of high-level tank wastes at the Hanford Site is currently envisioned to divide the waste between two principal waste forms: glass for the high-level waste (HLW) and grout for the low-level waste (LLW). The draft flow diagram shown in Figure 1.1 was developed as part of the current planning process for the Tank Waste Remediation System (TWRS), which is evaluating options for tank cleanup. The TWRS has been established by the US Department of Energy (DOE) to safely manage the Hanford tank wastes. It includes tank safety and waste disposal issues, as well as the waste pretreatment and wastemore » minimization issues that are involved in the ``clean option`` discussed in this report. This report describes the results of a study led by Pacific Northwest Laboratory to determine if a more aggressive separations scheme could be devised which could mitigate concerns over the quantity of the HLW and the toxicity of the LLW produced by the reference system. This aggressive scheme, which would meet NRC Class A restrictions (10 CFR 61), would fit within the overall concept depicted in Figure 1.1; it would perform additional and/or modified operations in the areas identified as interim storage, pretreatment, and LLW concentration. Additional benefits of this scheme might result from using HLW and LLW disposal forms other than glass and grout, but such departures from the reference case are not included at this time. The evaluation of this aggressive separations scheme addressed institutional issues such as: radioactivity remaining in the Hanford Site LLW grout, volume of HLW glass that must be shipped offsite, and disposition of appropriate waste constituents to nonwaste forms.« less

A cost-benefit analysis of produced water management opportunities in selected unconventional oil and gas plays

NASA Astrophysics Data System (ADS)

Marsters, P.; Macknick, J.; Bazilian, M.; Newmark, R. L.

2013-12-01

Unconventional oil and gas production in North America has grown enormously over the past decade. The combination of horizontal drilling and hydraulic fracturing has made production from shale and other unconventional resources economically attractive for oil and gas operators, but has also resulted in concerns over potential water use and pollution issues. Hydraulic fracturing operations must manage large volumes of water on both the front end as well as the back end of operations, as significant amounts of water are coproduced with hydrocarbons. This water--often called flowback or produced water--can contain chemicals from the hydraulic fracturing fluid, salts dissolved from the source rock, various minerals, volatile organic chemicals, and radioactive constituents, all of which pose potential management, safety, and public health issues. While the long-term effects of hydraulic fracturing on aquifers, drinking water supplies, and surface water resources are still being assessed, the immediate impacts of produced water on local infrastructure and water supplies are readily evident. Produced water management options are often limited to underground injection, disposal at centralized treatment facilities, or recycling for future hydraulic fracturing operations. The costs of treatment, transport, and recycling are heavily dependent on local regulations, existing infrastructure, and technologies utilized. Produced water treatment costs also change over time during energy production as the quality of the produced water often changes. To date there is no publicly available model that evaluates the cost tradeoffs associated with different produced water management techniques in different regions. This study addresses that gap by characterizing the volume, qualities, and temporal dynamics of produced water in several unconventional oil and gas plays; evaluating potential produced water management options, including reuse and recycling; and assessing how hydraulic fracturing and produced water issues relate to the larger water-energy nexus. Specifically, this study develops a play-specific model to compare the decision factors and costs involved in managing produced water. For example, when transport distances to a wastewater disposal site are far enough, options for recycling water become more favorable, depending on the characteristics of each play. This model can provide policymakers and other interested parties with cost estimates of different water management options, including a better understanding of the costs and opportunities associated with recycling produced water. This work provides a cross-play assessment of produced water management options and costs and could serve as the foundation for more detailed analyses of opportunities to minimize hydraulic fracturing's impacts on freshwater resources.

The CCTC Quick-Reacting General War Gaming System (QUICK) Users Manual. Volume 3. Weapon Allocation Subsystem

DTIC Science & Technology

1978-04-15

analyst who is concerned with preparing the data base for a war game, selecting optional features of QUICK, designating control parameters, submitting...i/.,-j-t r? 70 ~ CoMPUIfE YsTIEM MANUAL CSM UM 9-77 VOLUME IIIC15 APRIL 1978 Lod COMMAND 9 \\.., & CONTROL 09 TECHNICAL . CENTER CCTC QUICK-REACTING...RECALC Mode ............................... 31 3.1.1.2 Non -RECALC Mode ........................... 31 3.1.1.3 Mode Selecti-n and JCL Consideration

Negative pressure wound therapy with Bio-Dome dressing technology in the treatment of complex wounds: a case series.

PubMed

Penny, H L; Spinazzola, J; Green, A; Rifkah, M; Faretta, M; Youshaw, D; Weaver, A; Zaki, P

2014-04-01

The treatment of complex wounds is difficult and not always effective. Various treatment options are used with varying degrees of success. Negative pressure wound therapy (NPWT) is a cost-efficient and effective way to help treat these wounds. The use of a vacuum device applies the negative pressure to the site of the wound and promotes waste removal and increases circulation and tissue formation. While various NPWT systems are currently on the market, we utilised the ConvaTec Engenex® system with Bio-DomeTM technology; however, our case study is not intended to advocate the specific use of this system, but instead focuses on the use of NPWT as a viable option for wound healing. Each of the following case study patients presented with difficult-to-heal wounds that failed traditional therapeutic approaches. Through the use of NPWT, our patients saw major wound size reductions. Each patient exhibited at least a 94% reduction in wound area, wound volume or both.

Satellite Power Study (SPS) concept definition study (Exhibit D). Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Hanley, G. M.

1981-01-01

Efforts concentrated on updating of the Rockwell reference concept, definition of new system options, studies of special emphasis topics, further definition of the transportation system, and further program definition. The Rockwell reference satellite concept has a gallium arsenide (GaAs) solar cell array having flat concentrators with an effective concentration ratio of 1.83at end of life. Alternatives to this concept includes solid state power amplifiers or magnetrons for dc/RF conversion and multibandgap solar cells for solar to dc energy conversion. Two solid state concepts were studied. It was determined that the magnetron approach was the lowest mass and cost system.

Bioresearch module design definition and space shuttle vehicle integration. Volume 3: Management and funding plan

NASA Technical Reports Server (NTRS)

1971-01-01

A description is given of the proposed project organization, documentation and reports, project planning, direction and control, related experience and facilities, and cost estimate data and options for the implementation of the bioresearch module development program.

GASP- General Aviation Synthesis Program. Volume 5: Weight

NASA Technical Reports Server (NTRS)

Hague, D.

1978-01-01

Subroutines for determining the weights of propulsion system related components and the airframe components of an aircraft configuration are presented. Subroutines that deal with design load conditions, aircraft balance, and tail sizing are included. Options for turbine and internal combustion engines are provided.

78 FR 68494 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-14

... Exchange does not wish to remove the concept of the Select Symbols (and corresponding fees structure) from... volume in the Removed Symbols. Finally, these fees for the Removed Symbols will be the same as for all...

Program to Optimize Simulated Trajectories (POST). Volume 2: Utilization manual

NASA Technical Reports Server (NTRS)

Bauer, G. L.; Cornick, D. E.; Habeger, A. R.; Petersen, F. M.; Stevenson, R.

1975-01-01

Information pertinent to users of the program to optimize simulated trajectories (POST) is presented. The input required and output available is described for each of the trajectory and targeting/optimization options. A sample input listing and resulting output are given.

Severe and fatal obstetric injury claims in relation to labor unit volume.

PubMed

Milland, Maria; Mikkelsen, Kim L; Christoffersen, Jens K; Hedegaard, Morten

2015-05-01

To assess possible association between the incidence of approved claims for severe and fatal obstetric injuries and delivery volume in Denmark. A nationwide panel study of labor units. Claimants seeking financial compensation due to injuries occurring in labor units in 1995-2012. Exposure information regarding the annual number of deliveries per labor unit was retrieved from the Danish National Birth Register. Outcome information was retrieved from the Danish Patient Compensation Association. Exposure was categorized in delivery volume quintiles as annual volume per labor unit: (10-1377), (1378-2016), (2017-2801), (2802-3861), (3862-6659). Five primary measures of outcome were used. Incidence rate ratios of (A) Submitted claims, (B) Approved claims, (C) Approved severe injury claims (120% degree of disability), (D) Approved fatal injury claims, and (C+D) Combined. 1 151 734 deliveries in 51 labor units and 1872 submitted claims were included. The incidence rate ratios of approved claims overall, of approved fatal injury claims, and of approved severe and fatal injuries combined increased significantly with decreasing annual delivery volume. Face value incidence rate ratios of approved severe injuries increased with decreasing labor unit volume, but the association did not reach statistical significance. High volume labor units appear associated with fewer approved and fewer fatal injury claims compared with units with less volume. The findings support the development towards consolidation of units in Denmark. A suggested option would be to tailor obstetric patient safety initiatives according to the delivery volume of individual labor units. © 2015 Nordic Federation of Societies of Obstetrics and Gynecology.

Space station systems analysis study. Part 2, Volume 3: Appendixes, Book 1. Program requirements documentation

NASA Technical Reports Server (NTRS)

1977-01-01

The objective elements representative of the kinds of space activities that will be supported by the space construction base (SCB) are discussed in (1) a brief mission overview including the primary purpose and general objectives; (2) descriptions of the processes involved (where applicable), the mission hardware, the principal activities to be undertaken, the test requirements, and the principal tests; and (3) the SCB requirements including such items as special devices (e.g., fabrication modules, assembly or construction fixtures, cranes, and airlocks), power, data management and communications, waste management, environmental control, safety, and logistics. Each program option is then described in terms of the objective elements it supports, its orbit, the general makeup of the SCB, the transportation approach, and the program schedule goals. The specific requirements that are imposed on the SCB in order to support program option L are given.

Blade loss transient dynamics analysis, volume 2. Task 2: TETRA 2 user's manual

NASA Technical Reports Server (NTRS)

Black, Gerald; Gallardo, Vincente C.

1986-01-01

This is the user's manual for the TETRA 2 Computer Code, a program developed in the NASA-Lewis Blade Loss Program. TETRA 2 calculates a turbine engine's dynamic structural response from applied stimuli. The calculation options are: (1) transient response; and (2) steady state forced response. Based on the method of modal syntheses, the program allows the use of linear, as well as nonlinear connecting elements. Both transient and steady state options can include: flexible Bladed Disk Module, and Nonlinear Connecting Elements (including deadband, hardening/softening spring). The transient option has the additional capability to calculate response with a squeeze film bearing module. TETRA 2 output is summarized in a plotfile which permits post processing such as FFT or graphical animation with the proper software and computer equipment.

An Inviscid Computational Study of an X-33 Configuration at Hypersonic Speeds

NASA Technical Reports Server (NTRS)

Prabhu, Ramadas K.

1999-01-01

This report documents the results of a study conducted to compute the inviscid longitudinal aerodynamic characteristics of a simplified X-33 configuration. The major components of the X-33 vehicle, namely the body, the canted fin, the vertical fin, and the body-flap, were simulated in the CFD (Computational Fluid Dynamic) model. The rear-ward facing surfaces at the base including the aerospike engine surfaces were not simulated. The FELISA software package consisting of an unstructured surface and volume grid generator and two inviscid flow solvers was used for this study. Computations were made for Mach 4.96, 6.0, and 10.0 with perfect gas air option, and for Mach 10 with equilibrium air option with flow condition of a typical point on the X-33 flight trajectory. Computations were also made with CF4 gas option at Mach 6.0 to simulate the CF4 tunnel flow condition. An angle of attack range of 12 to 48 deg was covered. The CFD results were compared with available wind tunnel data. Comparison was good at low angles of attack; at higher angles of attack (beyond 25 deg) some differences were found in the pitching moment. These differences progressively increased with increase in angle of attack, and are attributed to the viscous effects. However, the computed results showed the trends exhibited by the wind tunnel data.

Feasibility study for the Swaziland/Mozambique interconnector. Final report. Export trade information

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-11-01

This study, conducted by Black & Veatch, was funded by the U.S. Trade and Development Agency. The report, produced for the Ministry of National Resources, Energy and Environment (MNRE) of Swaziland, determines the least cost capacity expansion option to meet the future power demand and system reliability criteria of Swaziland, with particular emphasis on the proposed interconnector between Swaziland and Mozambique. Volume 2, the Final Report, contains the following sections: (1.0) Introduction; (2.0) Review of SEB Power System; (3.0) SEB Load Forecast and Review; (4.0) SEB Load Forecast Revision; (5.0) The SEB Need for Power; (6.0) SEB System Development Planmore » Review; (7.0) Southern Mozambique EdM power System Review; (8.0) Southern Mozambique EdM Energy and Demand; (9.0) Supply Side Capacity Options for Swaziland and Mozambique; (10.0) SEB Expansion Plan Development; (11.0) EdM Expansion Plan Development; (12.0) Cost Sharing of the Interconnector; (13.0) Enviroinmental Evaluation of Interconnector Options; (14.0) Generation/Transmission Trade Offs; (15.0) Draft Interconnection Agreement and Contract Packages; (16.0) Transmission System Study; (17.0) Automatic General Control; (18.0) Automatic Startup and Shutdown of Hydro Electric Power Plants; (19.0) Communications and Metering; (20.0) Conclusions and Recommendations; Appendix A: Demand Side Management Primer; Appendix B. PURPA and Avoided Cost Calculations.« less

Options for management of municipal solid waste in New York City: A preliminary comparison of health risks and policy implications

PubMed Central

Moy, Pearl; Krishnan, Nikhil; Ulloa, Priscilla; Cohen, Steven; Brandt-Rauf, Paul W.

2008-01-01

Landfill disposal and waste-to-energy (WTE) incineration remain the two principal options for managing municipal solid waste (MSW). One critical determinant of the acceptability of these options is the different health risks associated with each. In this analysis relying on published data and exposure modeling, we have performed health risk assessments for landfill disposal versus WTE treatment options for the management of New York City’s MSW. These are based on the realistic scenario of using a waste transfer station (WTS) in Brooklyn and then transporting the untreated MSW by truck to a landfill in Pennsylvania or using a WTE facility in Brooklyn and then transporting the resultant ash by truck to a landfill in Pennsylvania. The overall results indicate that the individual cancer risks for both options would be considered generally acceptable, although the risk from landfilling is approximately 5 times greater than from WTE treatment; the individual non-cancer health risks for both options would be considered generally unacceptable, although once again the risk from landfilling is approximately 5 times greater than from WTE treatment. If one considers only the population in Brooklyn that would be directly affected by the siting of either a WTS or a WTE facility in their immediate neighborhood, individual cancer and non-cancer health risks for both options would be considered generally acceptable, but risks for the former remain considerably higher than for the latter. These results should be considered preliminary due to several limitations of this study such as: consideration of risks only from inhalation exposures; assumption that only volume and not composition of the waste stream is altered by WTE treatment; reliance on data from the literature rather than actual measurements of the sites considered, assuming comparability of the sites. However, the results of studies such as this, in conjunction with ecological, socioeconomic and equity considerations, should prove useful to environmental managers, regulators, policy makers, community representatives and other stakeholders in making sound and acceptable decisions regarding the optimal handling of MSW. PMID:17379391

Solar power satellite system definition study. Volume 1: Executive summary, phase 3

NASA Technical Reports Server (NTRS)

1980-01-01

Results of a three phase study of the Solar Power Satellite System are summarized. Various options and alternate systems were considered and the following conclusions were reached: antenna mounted solid state transmitters are potentially as cost effective as the klystron approach, althrough limited to 2500 megawatts net output; the free electron laser and optical diode laser appear most promising for laser power transmission; ground antenna siting need not be restricted to below 35 degrees of latitude; and nonrecurring cost reductions attainable by using a smaller Heavy Lift Launch Vehicle are highly attractive.

Standard spacecraft economic analysis. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Harris, E. D.; Large, J. P.

1976-01-01

A study of the comparative program costs associated with use of various standardized spacecraft for Air Force space test program missions to be flown on the space shuttle during the 1980-1990 time period is reviewed. The first phase of the study considered a variety of procurement mixes composed of existing or programmed NASA standard spacecraft designs and a Air Force standard spacecraft design. The results were briefed to a joint NASA/Air Force audience on July 11, 1976. The second phase considered additional procurement options using an upgraded version of an existing NASA design. The results of both phases are summarized.

Systems design study of the Pioneer Venus spacecraft. Volume 2. Preliminary program development plan

NASA Technical Reports Server (NTRS)

1973-01-01

The preliminary development plan for the Pioneer Venus program is presented. This preliminary plan treats only developmental aspects that would have a significant effect on program cost. These significant development areas were: master program schedule planning; test planning - both unit and system testing for probes/orbiter/ probe bus; ground support equipment; performance assurance; and science integration Various test planning options and test method techniques were evaluated in terms of achieving a low-cost program without degrading mission performance or system reliability. The approaches studied and the methodology of the selected approach are defined.

Integrated economic and experimental framework for screening of primary recovery technologies for high cell density CHO cultures

PubMed Central

Popova, Daria; Stonier, Adam; Pain, David; Titchener‐Hooker, Nigel J.

2016-01-01

Abstract Increases in mammalian cell culture titres and densities have placed significant demands on primary recovery operation performance. This article presents a methodology which aims to screen rapidly and evaluate primary recovery technologies for their scope for technically feasible and cost‐effective operation in the context of high cell density mammalian cell cultures. It was applied to assess the performance of current (centrifugation and depth filtration options) and alternative (tangential flow filtration (TFF)) primary recovery strategies. Cell culture test materials (CCTM) were generated to simulate the most demanding cell culture conditions selected as a screening challenge for the technologies. The performance of these technology options was assessed using lab scale and ultra scale‐down (USD) mimics requiring 25–110mL volumes for centrifugation and depth filtration and TFF screening experiments respectively. A centrifugation and depth filtration combination as well as both of the alternative technologies met the performance selection criteria. A detailed process economics evaluation was carried out at three scales of manufacturing (2,000L, 10,000L, 20,000L), where alternative primary recovery options were shown to potentially provide a more cost‐effective primary recovery process in the future. This assessment process and the study results can aid technology selection to identify the most effective option for a specific scenario. PMID:27067803

Low Tidal Volume Ventilation in Patients without Acute Respiratory Distress Syndrome: A Paradigm Shift in Mechanical Ventilation

PubMed Central

Lipes, Jed; Bojmehrani, Azadeh; Lellouche, Francois

2012-01-01

Protective ventilation with low tidal volume has been shown to reduce morbidity and mortality in patients suffering from acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Low tidal volume ventilation is associated with particular clinical challenges and is therefore often underutilized as a therapeutic option in clinical practice. Despite some potential difficulties, data have been published examining the application of protective ventilation in patients without lung injury. We will briefly review the physiologic rationale for low tidal volume ventilation and explore the current evidence for protective ventilation in patients without lung injury. In addition, we will explore some of the potential reasons for its underuse and provide strategies to overcome some of the associated clinical challenges. PMID:22536499

Technology assessment of changes in the future use and characteristics of the automobile transportation system. Volume 2 : technical report

DOT National Transportation Integrated Search

1979-02-01

This assessment of the automobile transportation system examines the automobile as a mode of personal transportation and considers issues and policy options pertaining to vehicles, highways, and related industries, services, and institutions. The ass...

Higher Donor Apheresis Blood Volumes Are Associated with Reduced Relapse Risk and Improved Survival in Reduced-Intensity Allogeneic Transplantations with Unrelated Donors.

PubMed

Crisalli, Lisa M; Hinkle, Joanne T; Walling, Christopher C; Sell, Mary; Frey, Noelle V; Hexner, Elizabeth O; Loren, Alison W; Luger, Selina M; Stadtmauer, Edward A; Porter, David L; Reshef, Ran

2018-06-01

Allogeneic hematopoietic stem cell transplantation (HSCT) with reduced-intensity conditioning (RIC) offers a curative option for patients with hematologic malignancies who are unable to undergo myeloablative conditioning, but its success is limited by high rates of relapse. Several studies have suggested a role for T cell doses in peripheral blood stem cell grafts in RIC HSCT. Because T cell dose is typically not known until after the collection, and apheresis blood volume is easily modifiable, we hypothesized that higher donor apheresis blood volumes would improve transplantation outcomes through an effect on graft composition. Thus, we analyzed the relationships between apheresis volume, graft composition, and transplantation outcomes in 142 consecutive patients undergoing unrelated donor allogeneic RIC HSCT. We found that apheresis volume ≥15 L was associated with a significantly decreased risk of relapse (adjusted hazard ratio [aHR], .48; 95% confidence interval [CI], .28 to .84]; P = .01) and improved relapse-free survival (aHR, .56; 95% CI, .35 to .89; P = .02) and overall survival (aHR, .55; 95% CI, .34 to .91; P = .02). A high apheresis volume was not associated with increased rates of acute or chronic graft-versus-host disease. These results demonstrate that an apheresis volume of at least 15 L is independently predictive of improved transplantation outcomes after RIC allogeneic HSCT. Copyright © 2018 The American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

Proceedings of the conference on coastal erosion and wetland modification in Louisiana: causes, consequences, and options

USGS Publications Warehouse

Boesch, Donald F.

1982-01-01

This volume contains 16 papers and panel discussions from a conference held in Baton Rouge, La., 5-6 October 1981. The presentations consider the causes and consequences of coastal erosion and wetland modification in Louisiana and the mitigative options available to slow or reverse the rapid rate of coastal land loss. Detailed habitat mapping studies have allowed accurate estimates of coastal habitat change and land loss through 1978. Projections from these rates of change indicate an annual rate of land loss in coastal Louisiana in the early 1980's of approximately 130 km2/yr (50 m2/yr).The projected effects of wetland modification on the bountiful living resources of coastal Louisiana (fisheries, fur and hide bearers and waterfowl) are major because of the close dependence of these resources on estuarine wetlands. These changes and others related to flood protection, transportation and ownership of mineral resources are projected to have extensive social and economic consequences.Options proposed to slow coastal land loss include major and minor diversion of the Mississippi River, barrier island and shoreline restoration protection, hydrological management of wetlands and more restrictive permitting of dredging activities.

Cost-effectiveness Analysis for Technology Acquisition.

PubMed

Chakravarty, A; Naware, S S

2008-01-01

In a developing country with limited resources, it is important to utilize the total cost visibility approach over the entire life-cycle of the technology and then analyse alternative options for acquiring technology. The present study analysed cost-effectiveness of an "In-house" magnetic resonance imaging (MRI) scan facility of a large service hospital against outsourcing possibilities. Cost per unit scan was calculated by operating costing method and break-even volume was calculated. Then life-cycle cost analysis was performed to enable total cost visibility of the MRI scan in both "In-house" and "outsourcing of facility" configuration. Finally, cost-effectiveness analysis was performed to identify the more acceptable decision option. Total cost for performing unit MRI scan was found to be Rs 3,875 for scans without contrast and Rs 4,129 with contrast. On life-cycle cost analysis, net present value (NPV) of the "In-house" configuration was found to be Rs-(4,09,06,265) while that of "outsourcing of facility" configuration was Rs-(5,70,23,315). Subsequently, cost-effectiveness analysis across eight Figures of Merit showed the "In-house" facility to be the more acceptable option for the system. Every decision for acquiring high-end technology must be subjected to life-cycle cost analysis.

MHOST version 4.2. Volume 1: Users' manual

NASA Technical Reports Server (NTRS)

Nakazawa, Shohei

1989-01-01

This manual describes the user options available for running the MHOST finite element analysis package. MHOST is a solid and structural analysis program based on mixed finite element technology, and is specifically designed for three-dimensional inelastic analysis. A family of two- and three-dimensional continuum elements along with beam and shell structural elements can be utilized. Many options are available in the constitutive equation library, the solution algorithms and the analysis capabilities. An overview of the algorithms, a general description of the input data formats, and a discussion of input data for selecting solution algorithms are given.

Comparative Evaluation of Cutting Methods of Activated Concrete from Nuclear Power Plant Decommissioning - 13548

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, HakSoo; Chung, SungHwan; Maeng, SungJun

2013-07-01

The amount of radioactive wastes from decommissioning of a nuclear power plant varies greatly depending on factors such as type and size of the plant, operation history, decommissioning options, and waste treatment and volume reduction methods. There are many methods to decrease the amount of decommissioning radioactive wastes including minimization of waste generation, waste reclassification through decontamination and cutting methods to remove the contaminated areas. According to OECD/NEA, it is known that the radioactive waste treatment and disposal cost accounts for about 40 percentage of the total decommissioning cost. In Korea, it is needed to reduce amount of decommissioning radioactivemore » waste due to high disposal cost, about $7,000 (as of 2010) per a 200 liter drum for the low- and intermediate-level radioactive waste (LILW). In this paper, cutting methods to minimize the radioactive waste of activated concrete were investigated and associated decommissioning cost impact was assessed. The cutting methods considered are cylindrical and volume reductive cuttings. The study showed that the volume reductive cutting is more cost-effective than the cylindrical cutting. Therefore, the volume reductive cutting method can be effectively applied to the activated bio-shield concrete. (authors)« less

Conductive resins improve charging and resolution of acquired images in electron microscopic volume imaging

PubMed Central

Nguyen, Huy Bang; Thai, Truc Quynh; Saitoh, Sei; Wu, Bao; Saitoh, Yurika; Shimo, Satoshi; Fujitani, Hiroshi; Otobe, Hirohide; Ohno, Nobuhiko

2016-01-01

Recent advances in serial block-face imaging using scanning electron microscopy (SEM) have enabled the rapid and efficient acquisition of 3-dimensional (3D) ultrastructural information from a large volume of biological specimens including brain tissues. However, volume imaging under SEM is often hampered by sample charging, and typically requires specific sample preparation to reduce charging and increase image contrast. In the present study, we introduced carbon-based conductive resins for 3D analyses of subcellular ultrastructures, using serial block-face SEM (SBF-SEM) to image samples. Conductive resins were produced by adding the carbon black filler, Ketjen black, to resins commonly used for electron microscopic observations of biological specimens. Carbon black mostly localized around tissues and did not penetrate cells, whereas the conductive resins significantly reduced the charging of samples during SBF-SEM imaging. When serial images were acquired, embedding into the conductive resins improved the resolution of images by facilitating the successful cutting of samples in SBF-SEM. These results suggest that improving the conductivities of resins with a carbon black filler is a simple and useful option for reducing charging and enhancing the resolution of images obtained for volume imaging with SEM. PMID:27020327

Three-dimensional remodeling of young Asian women's faces using 20-mg/ml smooth, highly cohesive, viscous hyaluronic acid fillers: a retrospective study of 320 patients.

PubMed

Bae, Jung Min; Lee, Dong Won

2013-09-01

Because Asian faces are generally flatter than Caucasian faces, Asian women are increasingly requesting facial volume enhancement. To clarify the effectiveness and safety of a volumizing treatment using 20-mg/mL smooth, highly cohesive, viscous hyaluronic acid fillers in young Asian women. We retrospectively reviewed 320 patients who had been treated with this filler from March 2010 to February 2012. The filler was injected in the shape of a diamond to the glabella, both malar eminences, and chin. Overall, 4 to 6 mL of filler was sufficient to enhance the volume of a face in young Asian women. Both the physicians and patients rated effectiveness on the Global Aesthetic Improvement Scale at week 4. Need for touch-up and any adverse events were also evaluated. Most patients were very satisfied with this volumizing procedure, and there were no major complications. The 20-mg/mL smooth, highly cohesive, viscous hyaluronic acid filler is an effective, well-tolerated treatment option in young Asian women wishing for a more-three-dimensional profile. © 2013 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.

Mid-term results of cardiac autotransplantation as method to treat permanent atrial fibrillation and mitral disease.

PubMed

Troise, Giovanni; Cirillo, Marco; Brunelli, Federico; Tasca, Giordano; Amaducci, Andrea; Mhagna, Zen; Tomba, Margherita Dalla; Quaini, Eugenio

2004-06-01

The results of current surgical options for the treatment of permanent atrial fibrillation (AF) associated with mitral surgery are widely different, particularly in very enlarged left atria. The aim of this study was to assess the mid-term efficacy of cardiac autotransplantation for this goal, through a consistent reduction of left atrium volume and a complete isolation of the pulmonary veins. From April 2000 to September 2002, 30 patients (male/female 5/25) underwent cardiac autotransplantation for the treatment of mitral valve disease and concomitant permanent AF (>1 year). Surgical technique of bicaval heart transplantation was modified maintaining the connection of inferior vena cava in all but three cases. Twenty-eight patients had mitral valve replacement and two had mitral valve repair. Associated procedures were: aortic valve replacement (6 cases), tricuspid valve repair (2 cases), coronary re-vascularization (2 cases) and right atrium volume reduction (4 cases). No hospital death occurred; 1 patient died 3 months post-operatively for pneumonia. At a mean follow-up of 21.1+/-7.7 months (range 6-35), 26 patients (89.7%) were in sinus rhythm and 3 (10.3%) in AF. Santa Cruz Score was 0 in 3 patients, 2 in 2 patients and 4 in the remaining 24 patients (82.7%). Mean left atrial diameter and volume decreased from 65.1+/-16.4 mm (range 50-130 mm) to 49.9+/-8.4 mm (range 37-78) (P < 0.001) and from 118.3+/-68.4 ml (range 60-426) to 69.4+/-34.1 ml (range 31-226) (P = 0.001), respectively, after the operation. Cardiac autotransplantation is a safe and effective option for the treatment of permanent AF in patients with mitral valve disease and severe dilation of left atrium.

Green-blue water in the city: quantification of impact of source control versus end-of-pipe solutions on sewer and river floods.

PubMed

De Vleeschauwer, K; Weustenraad, J; Nolf, C; Wolfs, V; De Meulder, B; Shannon, K; Willems, P

2014-01-01

Urbanization and climate change trends put strong pressures on urban water systems. Temporal variations in rainfall, runoff and water availability increase, and need to be compensated for by innovative adaptation strategies. One of these is stormwater retention and infiltration in open and/or green spaces in the city (blue-green water integration). This study evaluated the efficiency of three adaptation strategies for the city of Turnhout in Belgium, namely source control as a result of blue-green water integration, retention basins located downstream of the stormwater sewers, and end-of-pipe solutions based on river flood control reservoirs. The efficiency of these options is quantified by the reduction in sewer and river flood frequencies and volumes, and sewer overflow volumes. This is done by means of long-term simulations (100-year rainfall simulations) using an integrated conceptual sewer-river model calibrated to full hydrodynamic sewer and river models. Results show that combining open, green zones in the city with stormwater retention and infiltration for only 1% of the total city runoff area would lead to a 30 to 50% reduction in sewer flood volumes for return periods in the range 10-100 years. This is due to the additional surface storage and infiltration and consequent reduction in urban runoff. However, the impact of this source control option on downstream river floods is limited. Stormwater retention downstream of the sewer system gives a strong reduction in peak discharges to the receiving river. However due to the difference in response time between the sewer and river systems, this does not lead to a strong reduction in river flood frequency. The paper shows the importance of improving the interface between urban design and water management, and between sewer and river flood management.

Engineering assessment of inactive uranium mill tailings, Durango site, Durango, Colorado. A summary of the Phase II, Title I

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1977-11-01

Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Durango, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and other radium-contaminated materials, the evaluation of resulting radiation exposures of individuals and nearby populations, the investigation of site hydrology and meteorology and the evaluation and costing of alternative corrective actions. Radon gas release from the 1.555 million tons of tailings at the Durango site constitutesmore » the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The eight alternative actions presented range from vegetative stabilization (Option I), to contouring and stabilizing in-place with varying depths of cover material (Options II and III), to removal to an isolated long-term disposal site (Options V to VIII). All options include remedial action costs for offsite locations where tailings have been placed. Costs estimated for the eight options range from $4,340,000 to $13,590,000. Reprocessing the tailings for uranium is sufficiently economically attractive to justify reprocessing in conjunction with each of the options.« less

Engineering assessment of inactive uranium mill tailings, Durango site, Durango, Colorado. Phase II, Title I

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1977-11-01

Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Durango, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and other radium-contaminated materials, the evaluation of resulting radiation exposures of individuals and nearby populations, the investigation of site hydrology and meteorology and the evaluation and costing of alternative corrective actions. Radon gas release from the 1.555 million tons of tailings at the Durango site constitutesmore » the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The eight alternative actions presented range from vegetative stabilization (Option I), to contouring and stabilizing in-place with varying depths of cover material (Options II and III), to removal to an isolated long-term disposal site (Options V to VIII). All options include remedial action costs for offsite locations where tailings have been placed. Costs estimated for the eight options range from $4,340,000 to $13,590,000. Reprocessing the tailings for uranium is sufficiently economically attractive to justify reprocessing in conjunction with each of the options.« less

78 FR 69711 - Change in Postal Rates

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-20

.... Domestic Extra Services. Premium Forwarding Service prices increase slightly, and a new pricing option is... volume threshold for cubic pricing and other Commercial Plus offerings are decreased to 50,000 packages... methods for which GXG Commercial Base and PMEI Commercial Base pricing is available; the establishment of...

Analysis of alternative means of transporting heavy tracked vehicles at Fort Hood, Texas

DOT National Transportation Integrated Search

1987-08-01

The problem addressed in this report is a transportation problem--Given that a volume of heavy tracked vehicles must be moved from storage and maintenance locations to field training and other locations, what is the best way to move them? The options...

Computer-Generated Phase Diagrams for Binary Mixtures.

ERIC Educational Resources Information Center

Jolls, Kenneth R.; And Others

1983-01-01

Computer programs that generate projections of thermodynamic phase surfaces through computer graphics were used to produce diagrams representing properties of water and steam and the pressure-volume-temperature behavior of most of the common equations of state. The program, program options emphasizing thermodynamic features of interest, and…

Modal Traffic Impacts of Waterway User Charges : Volume 1. Recovery Options and Impacts Summary.

DOT National Transportation Integrated Search

1977-08-01

The report has considered waterway user charges, which have been proposed as a method of cost recovery of Federal expenditures. The report has examined possible modal carrier and traffic impacts due to user charges on the inland river system, and pot...

Entrepreneurship in the Eighties. Monograph. Volume 3, Number 2.

ERIC Educational Resources Information Center

Oldham, Lea Leever

Vocational schools are an excellent breeding ground for entrepreneurs. In addition to such programs as the Free Enterprise Project at the Auburn Career Center (Lake County, Ohio), some vocational schools, including Auburn, offer optional, short-term entrepreneurial programs. Entrepreneurship training in secondary educational institutions is…

21 CFR 177.1556 - Polyaryletherketone resins.

Code of Federal Regulations, 2014 CFR

2014-04-01

... mole, as determined by light scattering measurements in sulfuric acid at room temperature. (b) Optional... at reflux temperature for 2 hours with the following solvents: Distilled water, 50 percent (by volume) ethyl alcohol in distilled water, 3 percent acetic acid (by weight) in distilled water, and n-heptane...

Space station analysis study. Part 2, Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1977-01-01

Objectives of the space station program requiring the support of man in space, either in the shuttle sortie mode or in extended duration facilities are identified and analyzed. A set of functional requirements was derived to identify specific technology advancement needs, tests to be conducted, and processes to be developed. Program options are summarized for: (1) satellite power system; (2) earth services; (3) space cosmological research and development; (4) space processing and manufacturing; (5) multidiscipline science laboratory; (6) sensor development facility; (7) living and working in space; and (8) orbital depot.

Tracking and Data Relay Satellite System configuration and tradeoff study. Volume 3: Atlas Centaur launched TDRSS. Part 2: Final Report, 22 August 1972 - 1 April 1973

NASA Technical Reports Server (NTRS)

1973-01-01

Configuration data and design information for the Atlas Centaur launched configuration are presented. Overall system definition, operations and control, and telecommunication service system, including link budgets, are discussed. A brief description of the user telecommunications equipment and ground station is presented. A summary description of the TDR spacecraft and all the subsystems is included. The data presented are largely in tabular form. A brief treatment of an optional configuration with enhanced telecommunications service is described.

Northwest Energy Policy Project. Energy conservation policy evaluation: study module IA. Final report. Volume I. Summary report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berney, R.E.; Butcher, W.R.; Carter, L.F.

1977-01-01

This summary report identifies potential energy conservation measures and evaluates measures and policy options not likely to be suitable for adoption in the Pacific Northwest. Potential and incentives for energy conservation are specifically identified in the residential, commercial, industrial, and transportation sectors and through urban design. Selection of preferable policies and estimation of response to policies are next discussed. Finally, a computer impact model for calculating energy savings and changes in the levels of residuals resulting from energy conservation activities is discussed. (MCW)

Space station needs, attributes and architectural options study. Volume 5: Cost benefits and programmatic analyses

NASA Technical Reports Server (NTRS)

1983-01-01

The science, applications, commercial, U.S. national security and space operations missions that would require or be materially benefited by the availability of a permanent manned space station in low Earth orbit are considered. Space station attributes and capabilities which will be necessary to satisfy these mission requirements are identified. Emphasis is placed on the identification and validation of potential users, their requirements, and the benefits accruing to them from the existence of a space station, and the programmatic and cost implications of a space station program.

Security in the Middle East

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wells, S.F. Jr.; Bruzonsky, M.A.

1986-01-01

The full range of U.S. security interests in the Middle East is covered in this volume of original contributions from prominent international scholars. Case studies of key countries emphasize the prospects for peaceful political, economic, and cultural change in the region. The Arab-Israeli conflict is examined with particular attention to the ''Palestine problem,'' U.S. policy and diplomacy, and the peace process. Finally, the involvement of the U.S. and the USSR and the policy options open to them are considered. Includes chapters on oil and its role in Middle-East security issues.

Dosimetric uncertainty in prostate cancer proton radiotherapy.

PubMed

Lin, Liyong; Vargas, Carlos; Hsi, Wen; Indelicato, Daniel; Slopsema, Roelf; Li, Zuofeng; Yeung, Daniel; Horne, Dave; Palta, Jatinder

2008-11-01

The authors we evaluate the uncertainty in proton therapy dose distribution for prostate cancer due to organ displacement, varying penumbra width of proton beams, and the amount of rectal gas inside the rectum. Proton beam treatment plans were generated for ten prostate patients with a minimum dose of 74.1 cobalt gray equivalent (CGE) to the planning target volume (PTV) while 95% of the PTV received 78 CGE. Two lateral or lateral oblique proton beams were used for each plan. The authors we investigated the uncertainty in dose to the rectal wall (RW) and the bladder wall (BW) due to organ displacement by comparing the dose-volume histograms (DVH) calculated with the original or shifted contours. The variation between DVHs was also evaluated for patients with and without rectal gas in the rectum for five patients who had 16 to 47 cc of visible rectal gas in their planning computed tomography (CT) imaging set. The uncertainty due to the varying penumbra width of the delivered protons for different beam setting options on the proton delivery system was also evaluated. For a 5 mm anterior shift, the relative change in the RW volume receiving 70 CGE dose (V70) was 37.9% (5.0% absolute change in 13.2% of a mean V70). The relative change in the BW volume receiving 70 CGE dose (V70) was 20.9% (4.3% absolute change in 20.6% of a mean V70) with a 5 mm inferior shift. A 2 mm penumbra difference in beam setting options on the proton delivery system resulted in the relative variations of 6.1% (0.8% absolute change) and 4.4% (0.9% absolute change) in V70 of RW and BW, respectively. The data show that the organ displacements produce absolute DVH changes that generally shift the entire isodose line while maintaining the same shape. The overall shape of the DVH curve for each organ is determined by the penumbra and the distance of the target in beam's eye view (BEV) from the block edge. The beam setting option producing a 2 mm sharper penumbra at the isocenter can reduce the magnitude of maximal doses to the RW by 2% compared to the alternate option utilizing the same block margin of 7 mm. The dose to 0.1 cc of the femoral head on the distal side of the lateral-posterior oblique beam is increased by 25 CGE for a patient with 25 cc of rectal gas. Variation in the rectal and bladder wall DVHs due to uncertainty in the position of the organs relative to the location of sharp dose falloff gradients should be accounted for when evaluating treatment plans. The proton beam delivery option producing a sharper penumbra reduces maximal doses to the rectal wall. Lateral-posterior oblique beams should be avoided in patients prone to develop a large amount of rectal gas.

Solid Geometric Modeling - The Key to Improved Materiel Acquisition from Concept to Deployment

DTIC Science & Technology

1984-09-01

M. J. Reisinger, "The GIFT Code User Manual; Volume I, Introduction and Input Requirements (U)," BRL Report No. 1802, July 1975. AD# A078364. 8 G...G. Kuehl, L. W. Bain, Jr., M. J. Reisinger, "The GIFT Code User Manual; Volume II, The Output Options (U)," USA ARRAOCOM Report No. 02189, Sep 79, AD...A078364 . • These results are plotted by a code called RunShot written by L. M. Rybak which takes input from GIFT and plots color shotlines on a

Lung volume reduction surgery in bronchopulmonary dysplasia.

PubMed

Siaplaouras, J; Heckmann, M; Reiss, I; Schaible, T; Waag, K L; Gortner, L

2003-06-01

We report on a female preterm infant of 29 wk gestational age, who developed acquired lobar emphysema after prolonged artificial ventilation secondary to respiratory disease syndrome and bronchopulmonary dysplasia. The infant underwent atypical segmentectomy at the age of 12 mo because of life-threatening hypoxaemia with pulmonary hypertension and failure of conservative treatment. Lung volume reduction surgery (LVRS) dramatically improved the respiratory function and resulted in adequate weight gain and psychomotor development. In selected cases LVRS can be an option for lobar emphysema in premature infants with severe bronchopulmonary dysplasia.

Effects of delayed-release dimethyl fumarate on MRI measures in the phase 3 CONFIRM study.

PubMed

Miller, David H; Fox, Robert J; Phillips, J Theodore; Hutchinson, Michael; Havrdova, Eva; Kita, Mariko; Wheeler-Kingshott, Claudia A M; Tozer, Daniel J; MacManus, David G; Yousry, Tarek A; Goodsell, Mary; Yang, Minhua; Zhang, Ray; Viglietta, Vissia; Dawson, Katherine T

2015-03-17

To evaluate the effects of oral delayed-release dimethyl fumarate (DMF; also known as gastro-resistant DMF) on MRI lesion activity and load, atrophy, and magnetization transfer ratio (MTR) measures from the Comparator and an Oral Fumarate in Relapsing-Remitting Multiple Sclerosis (CONFIRM) study. CONFIRM was a 2-year, placebo-controlled study of the efficacy and safety of DMF 240 mg twice (BID) or 3 times daily (TID) in 1,417 patients with relapsing-remitting multiple sclerosis (RRMS); subcutaneous glatiramer acetate 20 mg once daily was included as an active reference comparator. The number and volume of T2-hyperintense, T1-hypointense, and gadolinium-enhancing (Gd+) lesions, as well as whole brain volume and MTR, were assessed in 681 patients (MRI cohort). DMF BID and TID produced significant and consistent reductions vs placebo in the number of new or enlarging T2-hyperintense lesions and new nonenhancing T1-hypointense lesions after 1 and 2 years of treatment and in the number of Gd+ lesions at week 24, year 1, and year 2. Lesion volumes were also significantly reduced. Reductions in brain atrophy and MTR changes with DMF relative to placebo did not reach statistical significance. The robust effects on MRI active lesion counts and total lesion volume in patients with RRMS demonstrate the ability of DMF to exert beneficial effects on inflammatory lesion activity in multiple sclerosis, and support DMF therapy as a valuable new treatment option in RRMS. This study provides Class I evidence of reduction in brain lesion number and volume, as assessed by MRI, over 2 years of delayed-release DMF treatment. © 2015 American Academy of Neurology.

Cerebrospinal fluid volume measurements in hydrocephalic rats.

PubMed

Basati, Sukhraaj; Desai, Bhargav; Alaraj, Ali; Charbel, Fady; Linninger, Andreas

2012-10-01

Object Experimental data about the evolution of intracranial volume and pressure in cases of hydrocephalus are limited due to the lack of available monitoring techniques. In this study, the authors validate intracranial CSF volume measurements within the lateral ventricle, while simultaneously using impedance sensors and pressure transducers in hydrocephalic animals. Methods A volume sensor was fabricated and connected to a catheter that was used as a shunt to withdraw CSF. In vitro bench-top calibration experiments were created to provide data for the animal experiments and to validate the sensors. To validate the measurement technique in a physiological system, hydrocephalus was induced in weanling rats by kaolin injection into the cisterna magna. At 28 days after induction, the sensor was implanted into the lateral ventricles. After sealing the skull using dental cement, an acute CSF drainage/infusion protocol consisting of 4 sequential phases was performed with a pump. Implant location was confirmed via radiography using intraventricular iohexol contrast administration. Results Controlled CSF shunting in vivo with hydrocephalic rats resulted in precise and accurate sensor measurements (r = 0.98). Shunting resulted in a 17.3% maximum measurement error between measured volume and actual volume as assessed by a Bland-Altman plot. A secondary outcome confirmed that both ventricular volume and intracranial pressure decreased during CSF shunting and increased during infusion. Ventricular enlargement consistent with successful hydrocephalus induction was confirmed using imaging, as well as postmortem. These results indicate that volume monitoring is feasible for clinical cases of hydrocephalus. Conclusions This work marks a departure from traditional shunting systems currently used to treat hydrocephalus. The overall clinical application is to provide alternative monitoring and treatment options for patients. Future work includes development and testing of a chronic (long-term) volume monitoring system.

The multidimensional Self-Adaptive Grid code, SAGE, version 2

NASA Technical Reports Server (NTRS)

Davies, Carol B.; Venkatapathy, Ethiraj

1995-01-01

This new report on Version 2 of the SAGE code includes all the information in the original publication plus all upgrades and changes to the SAGE code since that time. The two most significant upgrades are the inclusion of a finite-volume option and the ability to adapt and manipulate zonal-matching multiple-grid files. In addition, the original SAGE code has been upgraded to Version 1.1 and includes all options mentioned in this report, with the exception of the multiple grid option and its associated features. Since Version 2 is a larger and more complex code, it is suggested (but not required) that Version 1.1 be used for single-grid applications. This document contains all the information required to run both versions of SAGE. The formulation of the adaption method is described in the first section of this document. The second section is presented in the form of a user guide that explains the input and execution of the code. The third section provides many examples. Successful application of the SAGE code in both two and three dimensions for the solution of various flow problems has proven the code to be robust, portable, and simple to use. Although the basic formulation follows the method of Nakahashi and Deiwert, many modifications have been made to facilitate the use of the self-adaptive grid method for complex grid structures. Modifications to the method and the simple but extensive input options make this a flexible and user-friendly code. The SAGE code can accommodate two-dimensional and three-dimensional, finite-difference and finite-volume, single grid, and zonal-matching multiple grid flow problems.

[Continuous low volume infusion of hydroxyethyl starch as an option of water balance correction in patients with gestosis].

PubMed

Zhurova, A A; Ekstrem, A V; Popov, A S

2010-01-01

The method of long-term continuous low-volume infusion of hydroxyethyl starch (low-flow low volume correction HES) is administrated for correction of fluid balance disorders. The method is aimed to improve the outcomes in preeclamsia patients with multiple organ dysfunction and failure, as the most severe manifestation of system inflammatory response syndrome. After 4 days of the intensive care with application of the developed method in patients with preeclamsia the total body water level is decreased to the normal physiological level, the oedemas are significantly reduced or ceased, the haemodynamics stabilizes, which leads to the reduce of neurologic symptoms. The suggested method of low-flow low volume correction HES, in dose of 15 ml/kg/day is a significant addition to the existing methods of homeostasis and preeclampsia correction.

Spinning fluids reactor

DOEpatents

Miller, Jan D; Hupka, Jan; Aranowski, Robert

2012-11-20

A spinning fluids reactor, includes a reactor body (24) having a circular cross-section and a fluid contactor screen (26) within the reactor body (24). The fluid contactor screen (26) having a plurality of apertures and a circular cross-section concentric with the reactor body (24) for a length thus forming an inner volume (28) bound by the fluid contactor screen (26) and an outer volume (30) bound by the reactor body (24) and the fluid contactor screen (26). A primary inlet (20) can be operatively connected to the reactor body (24) and can be configured to produce flow-through first spinning flow of a first fluid within the inner volume (28). A secondary inlet (22) can similarly be operatively connected to the reactor body (24) and can be configured to produce a second flow of a second fluid within the outer volume (30) which is optionally spinning.

Volume-weighted particle-tracking method for solute-transport modeling; Implementation in MODFLOW–GWT

USGS Publications Warehouse

Winston, Richard B.; Konikow, Leonard F.; Hornberger, George Z.

2018-02-16

In the traditional method of characteristics for groundwater solute-transport models, advective transport is represented by moving particles that track concentration. This approach can lead to global mass-balance problems because in models of aquifers having complex boundary conditions and heterogeneous properties, particles can originate in cells having different pore volumes and (or) be introduced (or removed) at cells representing fluid sources (or sinks) of varying strengths. Use of volume-weighted particles means that each particle tracks solute mass. In source or sink cells, the changes in particle weights will match the volume of water added or removed through external fluxes. This enables the new method to conserve mass in source or sink cells as well as globally. This approach also leads to potential efficiencies by allowing the number of particles per cell to vary spatially—using more particles where concentration gradients are high and fewer where gradients are low. The approach also eliminates the need for the model user to have to distinguish between “weak” and “strong” fluid source (or sink) cells. The new model determines whether solute mass added by fluid sources in a cell should be represented by (1) new particles having weights representing appropriate fractions of the volume of water added by the source, or (2) distributing the solute mass added over all particles already in the source cell. The first option is more appropriate for the condition of a strong source; the latter option is more appropriate for a weak source. At sinks, decisions whether or not to remove a particle are replaced by a reduction in particle weight in proportion to the volume of water removed. A number of test cases demonstrate that the new method works well and conserves mass. The method is incorporated into a new version of the U.S. Geological Survey’s MODFLOW–GWT solute-transport model.

40 CFR 797.1330 - Daphnid chronic toxicity test.

Code of Federal Regulations, 2010 CFR

2010-07-01

... an extended period of time. In this test guideline, mortality and reproduction (and optionally... exposure over a specified period of time. In this guideline, the effect measured is immobilization. (4..., wet weight) to the volume (liters) of test solution in a test chamber at a point in time or passing...

Librarians as Community Partners: An Outreach Handbook

ERIC Educational Resources Information Center

Smallwood, Carol, Ed.

2010-01-01

Including 66 focused snapshots of outreach in action, this resource reflects the creative solutions of librarians searching for new and innovative ways to build programs that meet customer needs while expanding the library's scope into the community. This contributed volume includes: (1) A huge array of program options for partnering with other…

Rapid economic analysis of northern hardwood stand improvement options

Treesearch

William B. Leak

1980-01-01

Data and methodology are provided for projecting basal area, diameter, volumes, and values by product for northern hardwood stands, and for determining the rate of return on stand improvement investments. The method is rapid, requires a minimum amount of information, and should prove useful for on-the-ground economic analyses.

Choosing a Scanner: Points To Consider before Buying a Scanner.

ERIC Educational Resources Information Center

Raby, Chris

1998-01-01

Outlines ten factors to consider before buying a scanner: size of document; type of document; color; speed and volume; resolution; image enhancement; image compression; optical character recognition; scanning subsystem; and the option to use a commercial bureau service. The importance of careful analysis of requirements is emphasized. (AEF)

Blade loss transient dynamics analysis. Volume 3: User's manual for TETRA program

NASA Technical Reports Server (NTRS)

Black, G. R.; Gallardo, V. C.; Storace, A. S.; Sagendorph, F.

1981-01-01

The users manual for TETRA contains program logic, flow charts, error messages, input sheets, modeling instructions, option descriptions, input variable descriptions, and demonstration problems. The process of obtaining a NASTRAN 17.5 generated modal input file for TETRA is also described with a worked sample.

76 FR 82332 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-30

.... Moreover, the competitive pressures from other exchanges in electronic orders and different business model... electronic business and compete with other exchanges for such business. The business models surrounding...). The specific volume thresholds of the Program's tiers were set based upon business determinations and...

Final environmental statement, Liquid Metal Fast Breeder Reactor Program. Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1975-12-01

Information is presented under the following section headings: LMFBR program options and their compatibility with the major issues affecting commercial development, Proposed Final Environmental Statement for the LMFBR program, December 1974, WASH-1535, supplemental material, and material relating to Proposed Final Environmental Statement review. (DG)

Airport offsite passenger service facilities : an option for improving landside access : volume 1 : definition, background, and opportunities.

DOT National Transportation Integrated Search

2008-01-01

Because transportation modes are diverse, intermodal connections take several forms. They may be comprised of a major hub, such as the Virginia Inland Port, which transfers freight between the truck and rail modes, or an improvement to an existing mo...

Model Offices: Flexible Options, Local Innovations.

ERIC Educational Resources Information Center

Perspective: Essays and Reviews of Issues in Employment Security and Employment and Training Programs, 1990

1990-01-01

This volume of an annual journal contains 17 articles that focus on model local offices of the employment security (ES) and training systems. The articles are arranged in three parts. Part I, on developing new initiatives, contains the following five articles: "A Public Employment Service for the 1990s" (Elizabeth Dole); "The…

Unmanned Multiple Exploratory Probe System (MEPS) for Mars observation. Volume 1: Trade analysis and design

NASA Technical Reports Server (NTRS)

Adams, Daniel E.; Crumbly, Christopher M.; Delp, Steve E.; Guidry, Michelle A.; Lisano, Michael E.; Packard, James D.; Striepe, Scott A.

1988-01-01

This report presents the unmanned Multiple Exploratory Probe Systems (MEPS), a space vehicle designed to observe the planet Mars in preparation for manned missions. The options considered for each major element are presented as a trade analysis, and the final vehicle design is defined.

77 FR 67847 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-14

... ex-dividend.\\5\\ Dividend strategy transactions are only executed by Market-Makers. The Exchange... Sliding Scale volume thresholds. However, because only Market- Makers execute dividend strategy trades and... from the list of strategy executions for which fee caps apply. Under the Exchange's current Fees...

Developing African Novice Researchers into Career Investigators: Innovative Options

ERIC Educational Resources Information Center

Tumwijukye, Henry; Motevalli, Mahnaz; Nambi, Sophia; Kyeyune, Isaac

2013-01-01

Over the last decade, Sub-Saharan Africa has experienced an increased volume of funding and training activities to support research capacity development. However, there are persistent deficits in the number of active investigators conducting independent research with their own grants. To address this deficit, research institutions need to find an…

40 CFR 797.1330 - Daphnid chronic toxicity test.

Code of Federal Regulations, 2013 CFR

2013-07-01

... an extended period of time. In this test guideline, mortality and reproduction (and optionally... exposure over a specified period of time. In this guideline, the effect measured is immobilization. (4..., wet weight) to the volume (liters) of test solution in a test chamber at a point in time or passing...

40 CFR 797.1330 - Daphnid chronic toxicity test.

Code of Federal Regulations, 2014 CFR

2014-07-01

... an extended period of time. In this test guideline, mortality and reproduction (and optionally... exposure over a specified period of time. In this guideline, the effect measured is immobilization. (4..., wet weight) to the volume (liters) of test solution in a test chamber at a point in time or passing...

40 CFR 797.1330 - Daphnid chronic toxicity test.

Code of Federal Regulations, 2011 CFR

2011-07-01

... an extended period of time. In this test guideline, mortality and reproduction (and optionally... exposure over a specified period of time. In this guideline, the effect measured is immobilization. (4..., wet weight) to the volume (liters) of test solution in a test chamber at a point in time or passing...

40 CFR 797.1330 - Daphnid chronic toxicity test.

Code of Federal Regulations, 2012 CFR

2012-07-01

... an extended period of time. In this test guideline, mortality and reproduction (and optionally... exposure over a specified period of time. In this guideline, the effect measured is immobilization. (4..., wet weight) to the volume (liters) of test solution in a test chamber at a point in time or passing...

Space station needs, attributes and architectural options. Volume 1, attachment 1: Executive summary NASA

NASA Technical Reports Server (NTRS)

1983-01-01

User alignment plan, physical and life sciences and applications, commercial requirements national security, space operations, user needs, foreign contacts, mission scenario analysis and architectural concepts, alternative systems concepts, mission operations architectural development, architectural analysis trades, evolution, configuration, and technology development are discussed.

Robotic equipment malfunction during robotic prostatectomy: a multi-institutional study.

PubMed

Lavery, Hugh J; Thaly, Rahul; Albala, David; Ahlering, Thomas; Shalhav, Arieh; Lee, David; Fagin, Randy; Wiklund, Peter; Dasgupta, Prokar; Costello, Anthony J; Tewari, Ashutosh; Coughlin, Geoff; Patel, Vipul R

2008-09-01

Robotic-assisted laparoscopic prostatectomy (RALP) is growing in popularity as a treatment option for prostate cancer. As a new technology, little is known regarding the reliability of the da Vinci robotic system. Intraoperative robotic equipment malfunction may force the surgeon to convert the procedure to an open or pure laparoscopic procedure, or possibly even abort the procedure. We report the first large-scale, multi-institutional review of robotic equipment malfunction. A questionnaire was designed to evaluate the rate of perioperative robotic malfunction during RALP. High-volume, experienced surgeons were asked to complete this evaluation based on the analysis of their data. Questions included the overall number of RALPs performed, the number of equipment malfunctions, the number of procedures that had to be converted or aborted, and the part of the robotic system that malfunctioned. Eleven institutions participated in the study with a median surgeon volume of 700 cases, accounting for a total case volume of 8240. Critical failure occurred in 34 cases (0.4%) leading to the cancellation of 24 cases prior to the procedure, and the conversion to two laparoscopic and eight open procedures. The most common components of the robot to malfunction were the arms and optical system. Critical robotic equipment malfunction is extremely rare in institutions that perform high volumes of RALPs, with a nonrecoverable malfunction rate of only 0.4%.

Geostationary platform systems concepts definition study. Volume 2: Technical, book 1

NASA Technical Reports Server (NTRS)

1980-01-01

The initial selection and definition of operational geostationary platform concepts is discussed. Candidate geostationary platform missions and payloads were identified from COMSAT, Aerospace, and NASA studies. These missions and payloads were cataloged; classified with to communications, military, or scientific uses; screened for application and compatibility with geostationary platforms; and analyzed to identify platform requirements. Two platform locations were then selected (Western Hemisphere - 110 deg W, and Atlantic - 15 deg W), and payloads allocated based on nominal and high traffic models. Trade studies were performed leading to recommendation of selected concepts. Of 30 Orbit Transfer Vehicle (0TV) configuration and operating mode options identified, 18 viable candidates compatible with the operational geostationary platform missions were selected for analysis. Each was considered using four platform operational modes - 8 or 16 year life, and serviced or nonserviced, providing a total of 72 OTV/platform-mode options. For final trade study concept selection, a cost program was developed considering payload and platform costs and weight; transportation unit and total costs for the shuttle and OTV; and operational costs such as assembly or construction time, mating time, and loiter time. Servicing costs were added for final analysis and recommended selection.

[Physiotherapy in Women with Overactive Bladder].

PubMed

Henscher, U; Tholen, R; Kirschner-Hermanns, R

2016-08-01

As regards treatment for overactive bladder, physiotherapeutic interventions can be seen as an alternative to drug treatment. Targeted pelvic floor and bladder training is used to decrease the number of voids and the incontinence episodes or to increase the average voided volume in women with overactive bladder (3 systematic reviews with evidence level 1/1a).An additional option to treat women with overactive bladder is to use functional electrical stimulation and magnetic stimulation.2 systematic reviews 1 2 and 2 RCTs 3 4 reveal a low level of evidence (2 studies with level 2/2b) for the use of electrical stimulation (transcutaneous, vaginal or transanal) to reduce incontinence episodes and the number of voids and to increase the average voided volume. The trial from Yamanishi et al. (2014) shows that magnetic stimulation has a positive effect 5. Further studies are needed to evaluate the benefit of conservative treatment procedures for overactive bladder. © Georg Thieme Verlag KG Stuttgart · New York.

Reuse of industrial sludge as construction aggregates.

PubMed

Tay, J H; Show, K Y; Hong, S Y

2001-01-01

Industrial wastewater sludge and dredged marine clay are high volume wastes that needed enormous space at landfill disposal sites. Due to the limitation of land space, there is an urgent need for alternative disposal methods for these two wastes. This study investigates the possibility of using the industrial sludge in combination with marine clay as construction aggregates. Different proportions of sludge and clay were made into round and angular aggregates. It was found that certain mix proportions could provide aggregates of adequate strength, comparable to that of conventional aggregates. Concrete samples cast from the sludge-clay aggregates yield compressive strengths in the range of 31.0 to 39.0 N/mm2. The results showed that the round aggregates of 100% sludge and the crush aggregates of sludge with up to 20% clay produced concrete of compressive strengths which are superior to that of 38.0 N/mm2 for conventional aggregate. The study indicates that the conversion of high volume wastes into construction materials is a potential option for waste management.

Salt as a mitigation option for decreasing nitrogen leaching losses from grazed pastures.

PubMed

Ledgard, Stewart F; Welten, Brendon; Betteridge, Keith

2015-12-01

The main source of nitrogen (N) leaching from grazed pastures is animal urine with a high N deposition rate (i.e. per urine patch), particularly between late summer and early winter. Salt is a potential mitigation option as a diuretic to induce greater drinking-water intake, increase urination frequency, decrease urine N concentration and urine N deposition rate, and thereby potentially decrease N leaching. This hypothesis was tested in three phases: a cattle metabolism stall study to examine effects of salt supplementation rate on water consumption, urination frequency and urine N concentration; a grazing trial to assess effects of salt (150 g per heifer per day) on urination frequency; and a lysimeter study on effects of urine N rate on N leaching. Salt supplementation increased cattle water intake. Urination frequency increased by up to 69%, with a similar decrease in urine N deposition rate and no change in individual urination volume. Under field grazing, sensors showed increased urination frequency by 17%. Lysimeter studies showed a proportionally greater decrease in N leaching with decreased urine N rate. Modelling revealed that this could decrease per-hectare N leaching by 10-22%. Salt supplementation increases cattle water intake and urination frequency, resulting in a lower urine N deposition rate and proportionally greater decrease in urine N leaching. Strategic salt supplementation in autumn/early winter with feed is a practical mitigation option to decrease N leaching in grazed pastures. © 2015 Society of Chemical Industry.

Advanced Platform Systems Technology study. Volume 3: Supporting data

NASA Technical Reports Server (NTRS)

1983-01-01

The overall study effort proceeded from the identification of 106 technology topics to the selection of 5 for detail trade studies. The technical issues and options were evaluated through the trade process. Finally, individual consideration was given to costs and benefits for the technologies identified for advancement. Eight priority technology items were identified for advancement. Supporting data generated during the trade selection and trade study process were presented. Space platform requirements, trade study and cost benefits analysis, and technology advancement planning are advanced. The structured approach used took advantage of a number of forms developed to ensure that a consistent approach was employed by each of the diverse specialists that participated. These forms were an intrinsic part of the study protocol.

Proceedings of Small Power Systems Solar Electric Workshop. Volume 2: Invited papers

NASA Technical Reports Server (NTRS)

Ferber, R. (Editor)

1978-01-01

The focus of this work shop was to present the committment to the development of solar thermal power plants for a variety of applications including utility applications. Workshop activities included panel discussions, formal presentations, small group interactive discussions, question and answer periods, and informal gatherings. Discussion on topics include: (1) solar power technology options; (2) solar thermal power programs currently underway at the DOE, JPL, Electric Power Research Institute (EPRI), and Solar Energy Research Institute (SERI); (3) power options competing with solar; (4) institutional issues; (5) environmental and siting issues; (6) financial issues; (7) energy storage; (8) site requirements for experimental solar installations, and (9) utility planning.

Requirements for a Device-Based Training and Testing Program for M1 Gunnery. Volume 2. Detailed Analyses and Results

DTIC Science & Technology

1988-03-01

Dtftntt A- 5 ACTIVITY J. ACQUIRE TAR6ET(S) A-» Part 3.1. SNI-CII For Ttrg«t(i) A-6 Option 3.1.1. Search Open Hatch-- 0 *y A-4 Option 3.1.2. Starch...gunner time in position 0 -10 D- 5 . Percent of engagements in which crew cuts were observed . . . 0 -11 0 -6. First-round performance of tank... 5 of VII IB are based on much smaller ns, i.e., usually less than 20. 0 -3 The Database The Grafenwöhr Table VIII data is implemented on an IBM

Portal Vein Embolization: State-of-the-Art Technique and Options to Improve Liver Hypertrophy.

PubMed

Huang, Steven Y; Aloia, Thomas A

2017-12-01

Portal vein embolization (PVE) is associated with a high technical and clinical success rate for induction of future liver remnant hypertrophy prior to surgical resection. The degree of hypertrophy is variable and depends on multiple factors, including technical aspects of the procedure and underlying chronic liver disease. For patients with insufficient liver volume following PVE, adjunctive techniques, such as intra-portal administration of stem cells, dietary supplementation, transarterial embolization, and hepatic vein embolization, are available. Our purpose is to review the state-of-the-art technique associated with high-quality PVE and to discuss options to improve hypertrophy of the future liver remnant.

Orbital volume augmentation using expandable hydrogel implants in acquired anophthalmia and phthisis bulbi.

PubMed

Kim, Esther Lee; Bernardino, Carlo Rob; Levin, Flora

2016-01-01

The purpose of this study is to describe our experience using expandable spherical hydrogel implants and injectable hydrogel pellets for orbital volume augmentation in cases of post-enucleation socket syndrome after acquired anophthalmia or phthisis bulbi. We retrospectively reviewed the clinical records of all adult patients who received an expandable hydrogel implant for orbital volume loss following enucleation or phthisis bulbi at the Emory Eye Center between 2004 and January 2007 and the Yale Eye Center between 2009 and 2011. The study included 9 women and 5 men with a mean age of 51.2 years old (range 35-76 years old). Follow-up spanned 6 to 71 months (median of 18.5 months). Four patients received spherical hydrogel implants and 10 patients received hydrogel pellet injections. On average, nine pellets (range 5-16) were placed in each patient over an average of 1.7 injections (range 1-3). Most commonly, five pellets were injected per session, as was the case for 13 of the 17 treatment sessions. Post-operative complications included 2 cases of pellet migration, one subcutaneously and one anteriorly due to insufficiently posterior implant placement, and 1 hospital admission for pain after injection of 10 pellets in one visit. All patients experienced an overall subjective improvement in cosmesis. Self-expandable hydrogel implants appear to offer several advantages over other existing options for orbital volume augmentation, as they are easy to place, generally well-tolerated, volume-titratable, and to the extent that our follow-up shows, may be a safe and durable means of treating orbital volume loss in patients with acquired anophthalmia and phthisis bulbi.

Extracellular Volume Detects Amyloidotic Cardiomyopathy and Correlates With Neurological Impairment in Transthyretin-familial Amyloidosis.

PubMed

Gallego-Delgado, María; González-López, Esther; Muñoz-Beamud, Francisco; Buades, Juan; Galán, Lucía; Muñoz-Blanco, Jose Luis; Sánchez-González, Javier; Ibáñez, Borja; Mirelis, Jesus G; García-Pavía, Pablo

2016-10-01

Cardiac involvement determines prognosis and treatment options in transthyretin-familial amyloidosis. Cardiac magnetic resonance T 1 mapping techniques are useful to assess myocardial extracellular volume. This study hypothesized that myocardial extracellular volume allows identification of amyloidotic cardiomyopathy and correlates with the degree of neurological impairment in transthyretin-familial amyloidosis. A total of 31 transthyretin-familial amyloidosis patients (19 mean age, 49 ± 12 years; 26 with the Val30Met mutation) underwent a T 1 mapping cardiac magnetic resonance study and a neurological evaluation with Neuropathy Impairment Score of the Lower Limb score, Norfolk Quality of Life questionnaire, and Karnofsky index. Five patients had cardiac amyloidosis (all confirmed by 99m Tc-DPD scintigraphy). Mean extracellular volume was increased in patients with cardiac amyloidosis (0.490 ± 0.131 vs 0.289 ± 0.035; P = .026). Extracellular volume correlated with age (R = 0.467; P = .008), N-terminal pro-B-type natriuretic peptide (R S = 0.846; P < .001), maximum wall thickness (R = 0.621; P < .001), left ventricular mass index (R = 0.685; P < .001), left ventricular ejection fraction (R = -0.378; P = .036), Neuropathy Impairment Score of the Lower Limb (R S = 0.604; P = .001), Norfolk Quality of Life questionnaire (R S = 0.529; P = .003) and Karnofsky index (R S = -0.517; P = .004). A cutoff value of extracellular volume of 0.357 was diagnostic of cardiac amyloidosis with 100% sensitivity and specificity (P < .001). Extracellular volume and N-terminal pro-B-type natriuretic peptide were the only cardiac parameters that significantly correlated with neurologic scores. Extracellular volume quantification allows identification of cardiac amyloidosis and correlates with the degree of neurological impairment in transthyretin-familial amyloidosis. This noninvasive technique could be a useful tool for early diagnosis of cardiac amyloidosis and to track cardiac and extracardiac amyloid disease. Copyright © 2016 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

Integrated national energy planning and management: methodology and application to Sri Lanka. World Bank technical paper

DOE Office of Scientific and Technical Information (OSTI.GOV)

Munasinghe, M.; Meier, P.

1988-01-01

Given the importance of energy in modern economies, the first part of the volume is devoted to examining some of the key conceptual and analytical tools available for energy-policy analysis and planning. Policy tools and institutional frameworks that will facilitate better energy management are also discussed. Energy-policy analysis is explained, while effective energy management techniques are discussed to achieve desirable national objectives, using a selected set of policies and policy instruments. In the second part of the volume, the actual application of the principles set out earlier is explained through a case study of Sri Lanka. The monograph integrates themore » many aspects of the short-term programs already begun with the options for the medium to long term, and ends with the outline of a long-term strategy for Sri Lanka.« less

Eating disorders, energy intake, training volume, and menstrual function in high-level modern rhythmic gymnasts.

PubMed

Sundgot-Borgen, J

1996-06-01

This study examined clinical and subclinical eating disorders (EDs) in young Norwegian modern rhythmic gymnasts. Subjects were 12 members of the national team, age 13-20 years, and individually matched nonathletic controls. All subjects participated in a structured clinical interview for EDs, medical examination, and dietary analysis. Two of the gymnasts met the DSM-III-R criteria for anorexia nervosa, and 2 met the criteria for anorexia athletica (a subclinical ED). All the gymnasts were dieting in spite of the fact that they were all extremely lean. The avoidance of maturity, menstrual irregularities, energy deficit, high training volume, and high frequency of injuries were common features among the gymnasts. Ther is a need to learn more about risk factors and the etiology of EDs in different sports. Coaches, parents, and athletes need more information about principles of proper nutrition and methods to achieve ideal body composition for optional health and athletic performance.

Management options of varicoceles

PubMed Central

Chan, Peter

2011-01-01

Varicocele is one of the most common causes of male infertility. Treatment options for varicoceles includes open varicocelectomy performed at various anatomical levels. Laparoscopic varicocelectomy has been established to be a safe and effective treatment for varicoceles. Robotic surgery has been introduced recently as an alternative surgical option for varicocelectomy. Microsurgical varicocelectomy has gained increasing popularity among experts in male reproductive medicine as the treatment of choice for varicocele because of its superior surgical outcomes. There is a growing volume of literature in the recent years on minimal invasive varicocele treatment with percutaneous retrograde and anterograde venous embolization/sclerotherapy. In this review, we will discuss the advantages and limitations associated with each treatment modality for varicoceles. Employment of these advanced techniques of varicocelectomy can provide a safe and effective approach aiming to eliminate varicocele, preserve testicular function and, in a substantial number of men, increase semen quality and the likelihood of pregnancy. PMID:21716892

Ground Operations Aerospace Language (GOAL). Volume 4: Interpretive code translator

NASA Technical Reports Server (NTRS)

1973-01-01

This specification identifies and describes the principal functions and elements of the Interpretive Code Translator which has been developed for use with the GOAL Compiler. This translator enables the user to convert a compliled GOAL program to a highly general binary format which is designed to enable interpretive execution. The translator program provides user controls which are designed to enable the selection of various output types and formats. These controls provide a means for accommodating many of the implementation options which are discussed in the Interpretive Code Guideline document. The technical design approach is given. The relationship between the translator and the GOAL compiler is explained and the principal functions performed by the Translator are described. Specific constraints regarding the use of the Translator are discussed. The control options are described. These options enable the user to select outputs to be generated by the translator and to control vrious aspects of the translation processing.

Strategies for the return of science data from in situ vehicles at Titan

NASA Astrophysics Data System (ADS)

Spilker, T. R.; Reh, K. R.; Erd, C.; Elliott, J. O.; Mohr, D.; Strange, N. J.

2009-04-01

Collaborative studies of the Titan Saturn System Mission (TSSM) in 2008 by ESA and NASA have included examination of strategies for optimizing the science return from that mission concept's proposed in situ elements. The current baselined mission concept calls for an orbiter provided and launched by NASA that would deliver to Titan and support two ESA-provided in situ elements, a lake lander whose science mission duration would be about nine hours, and a montgolfière (hot-air balloon) that would operate at ~10 km altitude in Titan's lower atmosphere for 6-12 months. This architecture has much in common with the highly successful Cassini-Huygens mission. The short-lived lake lander in particular would have a mission profile very similar to that of the Huygens probe, with all science data communications occurring while the NASA orbiter is relatively near Titan. Practical mission profile options for the montgolfière include extended periods when the NASA orbiter is farther from Titan, reducing data rates. Over long periods of time the montgolfière cannot be considered fixed over one location on Titan's surface, and in fact is expected to circumnavigate Titan in less than six months. Thus the schedule of communications windows between the in situ elements and the orbiter cannot be precisely determined far in advance, varying as the balloon literally "rides the wind". Other issues played critical roles in evaluating the many options available early in the studies. Some options for the timing of delivery of the in situ elements yielded more mass capability available for those elements, but their reduced data return due to orbit geometry outweighs the added mass capability. Another delivery option, delivery from Titan orbit, yields reduced delivery mass capability but was thought (before studies) to offer better data relay capability. Studies revealed that this strategy actually decreases the return from the lake lander as compared to options delivering the in situ elements from hyperbolic flybys. This presentation will describe options examined in the TSSM communications strategy studies. Particular attention is given to that chosen for the baseline strategy, with potential returned data volumes that provide generous margins over anticipated data requirements. Many of the results are not unique to Titan alone, but are applicable to in situ missions at any satellite of a giant planet. These collaborative studies were funded by, and performed under the cognizance of, NASA and ESA.

Viking '79 Rover study. Volume 1: Summary report

NASA Technical Reports Server (NTRS)

1974-01-01

The results of a study to define a roving vehicle suitable for inclusion in a 1979 Viking mission to Mars are presented. The study focused exclusively on the 1979 mission incorporating a rover that would be stowed on and deployed from a modified Viking lander. The overall objective of the study was to define a baseline rover, the lander/rover interfaces, a mission operations concept, and a rover development program compatible with the 1979 launch opportunity. During the study, numerous options at the rover system and subsystem levels were examined and a baseline configuration was selected. Launch vehicle, orbiter, and lander performance capabilities were examined to ensure that the baseline rover could be transported to Mars using minimum-modified Viking '75 hardware and designs.

Distributed fiber optic moisture intrusion sensing system

DOEpatents

Weiss, Jonathan D.

2003-06-24

Method and system for monitoring and identifying moisture intrusion in soil such as is contained in landfills housing radioactive and/or hazardous waste. The invention utilizes the principle that moist or wet soil has a higher thermal conductance than dry soil. The invention employs optical time delay reflectometry in connection with a distributed temperature sensing system together with heating means in order to identify discrete areas within a volume of soil wherein temperature is lower. According to the invention an optical element and, optionally, a heating element may be included in a cable or other similar structure and arranged in a serpentine fashion within a volume of soil to achieve efficient temperature detection across a large area or three dimensional volume of soil. Remediation, moisture countermeasures, or other responsive action may then be coordinated based on the assumption that cooler regions within a soil volume may signal moisture intrusion where those regions are located.

Public health assessment for Bloomington PCB sites, Bloomington, Monroe County, Indiana and Spencer, Owen County, Indiana. Region 5. Volumes 1, 2, and 3. Revised November 15, 1996. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Public Health Assessment for Bloomington PCB Sites (PHA) is the Agency for Toxic Substances and Disease Registry`s (ATSDR) evaluation of the public health impact of six sites in and around Bloomington, Indiana, and the public health considerations for technologies that could be used to remediate the sites. Volume I contains an evaluation of past, present, and future health implications based on available environmental and health outcome data and pathways of potential human exposure. Volume II summarizes a number of public health considerations that those selecting remedial options for both incineration and non-incineration remedial technologies for PCB wastes must evaluate.more » Volume III provides the bases for the overall conclusions and recommendations the agency reached regarding public health hazards associated with the Bloomington PCB sites under past, present, and future conditions.« less

Radiation and scattering from bodies of translation. Volume 2: User's manual, computer program documentation

NASA Astrophysics Data System (ADS)

Medgyesi-Mitschang, L. N.; Putnam, J. M.

1980-04-01

A hierarchy of computer programs implementing the method of moments for bodies of translation (MM/BOT) is described. The algorithm treats the far-field radiation and scattering from finite-length open cylinders of arbitrary cross section as well as the near fields and aperture-coupled fields for rectangular apertures on such bodies. The theoretical development underlying the algorithm is described in Volume 1. The structure of the computer algorithm is such that no a priori knowledge of the method of moments technique or detailed FORTRAN experience are presupposed for the user. A set of carefully drawn example problems illustrates all the options of the algorithm. For more detailed understanding of the workings of the codes, special cross referencing to the equations in Volume 1 is provided. For additional clarity, comment statements are liberally interspersed in the code listings, summarized in the present volume.

Metateaching and the Instructional Map. Teaching Techniques/Strategies Series, Volume 1.

ERIC Educational Resources Information Center

Timpson, William M.

This book describes a conceptual framework, the "Instructional Map"--a metaphor for envisioning the interconnectedness of teacher and student, teaching and learning, and content and process--that can help teachers plan, sort their way through course material and instructional options, interact with students, and reflect upon progress made and what…

Special Education Forms. Volume 1: School-Age Students.

ERIC Educational Resources Information Center

Fink, Sandra; And Others

This document comprises forms (and directions for their use) used in Oregon in conjunction with the Individuals with Disabilities Education Act (IDEA) for school-aged children. Forms are identified as either required or optional and are presented in a two-page format, with one page identifying the form, explaining its purposes, and providing…

75 FR 168 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving Proposed Rule Change Amending...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-04

... lower the minimum component stock weight requirement from 90% to 70% of the weight of the underlying... component stock trading volumes are determined on a global basis. Finally, as an option for meeting the... minimize potential manipulation. The Commission also believes that the proposed use of minimum notional...

An Integrative Approach to Foreign Language Teaching: Choosing Among the Options. ACTFL Foreign Language Education Series, Vol. 8.

ERIC Educational Resources Information Center

Jarvis, Gilbert A., Ed.

This volume on foreign language teaching and learning concerns the following topics: lifelong learning, small-group learning, the minicourse, student attitudes toward foreign languages, problems in secondary schools, humanistic education, curricula in uncommonly taught languages, foreign languages in elementary and adolescent-centered education,…

21 CFR 606.121 - Container label.

Code of Federal Regulations, 2011 CFR

2011-04-01

... payment for a blood donation. (ii) A volunteer donor is a person who does not receive monetary payment for... units of Red Blood Cells, the volume of the product, accurate to within ±10 percent; or optionally for.... The Rh group shall be designated as follows: (i) If the test using Anti-D Blood Grouping Reagent is...

21 CFR 606.121 - Container label.

Code of Federal Regulations, 2010 CFR

2010-04-01

... payment for a blood donation. (ii) A volunteer donor is a person who does not receive monetary payment for... units of Red Blood Cells, the volume of the product, accurate to within ±10 percent; or optionally for.... The Rh group shall be designated as follows: (i) If the test using Anti-D Blood Grouping Reagent is...

Management of Contaminants Stored in Low Permeability Zones - A State of the Science Review

DTIC Science & Technology

2013-10-01

Tank  3:     Permanganate  ...................................................................................................  193...Treatment options explored include steady water flushing (control), enhance water flushing, flushing permanganate , a dechlorinating culture (KB1...Remediation Tank Experiments (OoM: Order of Magnitude. PV: Pore Volume) 2. Enhanced flushing (79 PVs after loading) 3. Permanganate (45 PVs

77 FR 48570 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving a Proposed Rule...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-14

... Underlying Securities) of the NASDAQ Options Market rules.\\11\\ Additionally, the Target Component's and the...\\ Additionally, the Target Component's and the Benchmark Component's trading volume (in all markets in which the...-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving a Proposed Rule Change Relating to the...

Science and Engineering Indicators 2010. NSB 10-01

ERIC Educational Resources Information Center

Lehming, Rolf F.; Alt, Martha Naomi; Chen, Xianglei; Hall, Leslie; Burton, Lawrence; Burrelli, Joan S.; Kannankutty, Nirmala; Proudfoot, Steven; Regets, Mark C.; Boroush, Mark; Moris, Francisco A.; Wolfe, Raymond M.; Britt, Ronda; Christovich, Leslie; Hill, Derek; Falkenheim, Jaquelina C.; Dunnigan, Paula C.

2010-01-01

"Science and Engineering Indicators" (SEI) is first and foremost a volume of record comprising the major high-quality quantitative data on the U.S. and international science and engineering enterprise. SEI is factual and policy neutral. It does not offer policy options, and it does not make policy recommendations. SEI employs a variety…

Science and Engineering Indicators 2012. NSB 12-01

ERIC Educational Resources Information Center

National Science Foundation, 2012

2012-01-01

Science and Engineering Indicators (SEI) is first and foremost a volume of record comprising the major high-quality quantitative data on the U.S. and international science and engineering enterprise. SEI is factual and policy neutral. It does not offer policy options, and it does not make policy recommendations. SEI employs a variety of…

Standardization Plan for Fiber Optics Optional Phase. Volume 2.

DTIC Science & Technology

1984-01-01

Langley 1 ERADCOM 7 Johnson 1 ETL-TD-E 1 Johnson 1 MICOM 2 Ames 1 MIRADCOM 1 AVRADCOM 7 DARCOMW 14 Army Human Engineering 1 Laboratories NAVY DEPARTMENT...34- .- . . "-",..- -? ., .. .- " - , -- , - .--- ’- -.... . : ...- . . ..-. ..- ;.- SPECIFICATIONS DATA BASE Page 44 170. Automiated Sampled Data Instrumentation System CASDIS) Transmission Group CI 0042137 Number: S-M-X

Enterovaginal or Vesicovaginal Fistula Control Using a Silicone Cup.

PubMed

Russell, Katie W; Robinson, Ryan E; Mone, Mary C; Scaife, Courtney L

2016-12-01

An enterovaginal or vesicovaginal fistula is a complication resulting in vaginal discharge of succus, urine, or stool that can lead to significant complications. For low-volume fistulae, tampons or pads may be used. With high-volume fistulae, frequent product change can be painful and unpredictable in terms of efficacy. The psychologic distress is profound. Surgery may not be an option, making symptom control the priority. We report the use of a reusable menstrual silicone vaginal cup placed to divert and contain drainage. The menstrual cup provided significant symptom relief. Drainage is immediately diverted from tissue, unlike with tampon or pad use, which involves longer contact periods with caustic fluids. A system was created by adapting the end of the cup by adding silastic tubing and an external leg bag to provide long-term drainage control. Improvement in quality of life is of primary importance when dealing with fistula drainage. This simple and inexpensive device should be considered in those cases in which the drainage can be diverted as a viable option, especially in those who are symptomatic and awaiting surgical repair or in those for whom surgery cannot be performed.

Phase change thermal energy storage methods for combat vehicles, phase 1

NASA Astrophysics Data System (ADS)

Lynch, F. E.

1986-06-01

Three alternative cooling methods, based on latent heat absorption during phase changes, were studied for potential use in combat vehicle microclimate temperature control. Metal hydrides absorb heat as they release hydrogen gas. Plastic crystals change from one solid phase to another, absorbing heat in the process. Liquid air boils at cryogenic temperature and absorbs additional sensible heat as the cold gas mixes with the microclimate air flow. System designs were prepared for each of the three microclimate cooling concepts. These designs provide details about the three phase change materials, their containers and the auxiliary equipment needed to implement each option onboard a combat vehicle. The three concepts were compared on the basis of system mass, system volume and the energy required to regenerate them after use. Metal hydrides were found to be the lightest and smallest option by a large margin. The energy needed to regenerate a hydride thermal storage system can be extracted from the vehicle's exhaust gases.

Extended parametric representation of compressor fans and turbines. Volume 2: Part user's manual (parametric turbine)

NASA Technical Reports Server (NTRS)

Coverse, G. L.

1984-01-01

A turbine modeling technique has been developed which will enable the user to obtain consistent and rapid off-design performance from design point input. This technique is applicable to both axial and radial flow turbine with flow sizes ranging from about one pound per second to several hundred pounds per second. The axial flow turbines may or may not include variable geometry in the first stage nozzle. A user-specified option will also permit the calculation of design point cooling flow levels and corresponding changes in efficiency for the axial flow turbines. The modeling technique has been incorporated into a time-sharing program in order to facilitate its use. Because this report contains a description of the input output data, values of typical inputs, and example cases, it is suitable as a user's manual. This report is the second of a three volume set. The titles of the three volumes are as follows: (1) Volume 1 CMGEN USER's Manual (Parametric Compressor Generator); (2) Volume 2 PART USER's Manual (Parametric Turbine); (3) Volume 3 MODFAN USER's Manual (Parametric Modulation Flow Fan).

ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer.

PubMed

Nestle, Ursula; De Ruysscher, Dirk; Ricardi, Umberto; Geets, Xavier; Belderbos, Jose; Pöttgen, Christoph; Dziadiuszko, Rafal; Peeters, Stephanie; Lievens, Yolande; Hurkmans, Coen; Slotman, Ben; Ramella, Sara; Faivre-Finn, Corinne; McDonald, Fiona; Manapov, Farkhad; Putora, Paul Martin; LePéchoux, Cécile; Van Houtte, Paul

2018-04-01

Radiotherapy (RT) plays a major role in the curative treatment of locally advanced non-small cell lung cancer (NSCLC). Therefore, the ACROP committee was asked by the ESTRO to provide recommendations on target volume delineation for standard clinical scenarios in definitive (chemo)radiotherapy (RT) and adjuvant RT for locally advanced NSCLC. The guidelines given here are a result of the evaluation of a structured questionnaire followed by a consensus discussion, voting and writing procedure within the committee. Hence, we provide advice for methods and time-points of diagnostics and imaging before the start of treatment planning and for the mandatory and optional imaging to be used for planning itself. Concerning target volumes, recommendations are given for GTV delineation of primary tumour and lymph nodes followed by issues related to the delineation of CTVs for definitive and adjuvant radiotherapy. In the context of PTV delineation, recommendations about the management of geometric uncertainties and target motion are given. We further provide our opinions on normal tissue delineation and organisational and responsibility questions in the process of target volume delineation. This guideline intends to contribute to the standardisation and optimisation of the process of RT treatment planning for clinical practice and prospective studies. Copyright © 2018 Elsevier B.V. All rights reserved.

Evaluation of solar cells for potential space satellite power applications

NASA Technical Reports Server (NTRS)

1977-01-01

The evaluation focused on the following subjects: (1) the relative merits of alternative solar cell materials, based on performance and availability, (2) the best manufacturing methods for various solar cell options and the effects of extremely large production volumes on their ultimate costs and operational characteristics, (3) the areas of uncertainty in achieving large solar cell production volumes, (4) the effects of concentration ratios on solar array mass and system performance, (5) the factors influencing solar cell life in the radiation environment during transport to and in geosynchronous orbit, and (6) the merits of conducting solar cell manufacturing operations in space.

An investigation into pilot and system response to critical in-flight events. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Rockwell, T. H.; Griffin, W. C.

1981-01-01

Critical in-flight events (CIFE) that threaten the aircraft were studied. The scope of the CIFE was described and defined with emphasis on characterizing event development, detection and assessment; pilot information requirements, sources, acquisition, and interpretation, pilot response options, decision processed, and decision implementation and event outcome. Detailed scenarios were developed for use in simulators and paper and pencil testing for developing relationships between pilot performance and background information as well as for an analysis of pilot reaction decision and feedback processes. Statistical relationships among pilot characteristics and observed responses to CIFE's were developed.

Space station needs, attributes, and architectural options. Volume 1. Executive summary

NASA Technical Reports Server (NTRS)

Pritchard, E. B.

1983-01-01

The initial space station should be manned, placed in 28.5 deg orbit, and provide substantial economic, performance, and social benefits. The most beneficial space station capabilities include: a space test facility; a transport harbor; satellite servicing and assembly; and an observatory. A space industrial park could be added once further development effort validates the cost and expanding commercial market for space processed materials. The potential accrued gross mission model benefit derived from these capabilities is $5.9B without the industrial park, and $9.3B with it. An unclassified overview of all phases of the study is presented.

Modeling of Three Flat Coal Seams Strata Developing at Open Pit Miming

NASA Astrophysics Data System (ADS)

Gvozdkova, Tatiana; Markov, Sergey; Demirel, Nuray; Anyona, Serony

2017-11-01

The use of low-cost direct dumpling technology, as is well known, has a relatively limited field of application: flat coal seams, and the higher the dip angle of the seam, the more difficult it is to place the necessary volume of overburden rock in the dumping layers. For this, we have to pour four-tier dumps. In this article, four possible options for piling the dump have been studied and prerequisites have been made for further research aimed at improving the efficiency of the use of direct dumpling technology in the development of flat coal seams.

Beyond the Baseline 1991: Proceedings of the Space Station Evolution Symposium. Volume 1: Space Station Freedom, part 2

NASA Technical Reports Server (NTRS)

1991-01-01

This report contains the individual presentations delivered at the Space Station Evolution Symposium. The results of Space Station Freedom Advanced Studies provide a road map for the evolution of Freedom in terms of user requirements, utilization and operations concepts, and growth options for distributed systems. Regarding these specific systems, special attention is given to: highlighting changes made during restructuring; description of growth paths through the follow-on and evolution phases; identification of minimum impact provisions to allow flexibility in the baseline; and identification of enhancing and enabling technologies.

Asymmetrical booster ascent guidance and control system design study. Volume 5: Space shuttle powered explicit guidance. [space shuttle development

NASA Technical Reports Server (NTRS)

Jaggers, R. F.

1974-01-01

An optimum powered explicit guidance algorithm capable of handling all space shuttle exoatospheric maneuvers is presented. The theoretical and practical basis for the currently baselined space shuttle powered flight guidance equations and logic is documented. Detailed flow diagrams for implementing the steering computations for all shuttle phases, including powered return to launch site (RTLS) abort, are also presented. Derivation of the powered RTLS algorithm is provided, as well as detailed flow diagrams for implementing the option. The flow diagrams and equations are compatible with the current powered flight documentation.

VASCOMP 2. The V/STOL aircraft sizing and performance computer program. Volume 6: User's manual, revision 3

NASA Technical Reports Server (NTRS)

Schoen, A. H.; Rosenstein, H.; Stanzione, K.; Wisniewski, J. S.

1980-01-01

This report describes the use of the V/STOL Aircraft Sizing and Performance Computer Program (VASCOMP II). The program is useful in performing aircraft parametric studies in a quick and cost efficient manner. Problem formulation and data development were performed by the Boeing Vertol Company and reflects the present preliminary design technology. The computer program, written in FORTRAN IV, has a broad range of input parameters, to enable investigation of a wide variety of aircraft. User oriented features of the program include minimized input requirements, diagnostic capabilities, and various options for program flexibility.

Clinically localized prostate cancer in 2017: A review of comparative effectiveness.

PubMed

Lavery, Hugh J; Cooperberg, Matthew R

2017-02-01

Introducing the topic of comparative effectiveness for prostate cancer treatments with a reminder of the disease's heterogeneity risks tautology. However, the profound variation both in this cancer's biology and its clinical course is increasingly widely recognized, while management alternatives for clinically localized prostate cancer have exploded. Available options now include active surveillance, multiple surgical approaches to prostatectomy, various forms of external-beam and interstitial radiation, and a growing list of energy ablative technologies. Each treatment option has its own efficacy rate as well as its own set of complications, side effects and financial costs. Difficulties comparing these options, together with the high prevalence of the disease, led the Institute of Medicine to include localized prostate cancer among the top 25 priority conditions for future comparative effectiveness research. The sheer volume of possible treatment options, with their individual risks and benefits, can be confusing for patients and clinicians to research, understand and explain. To help clinicians navigate these treatment options, we have assembled this Urologic Oncology Seminar on the comparative effectiveness of treatments for clinically localized prostate cancer. The articles focus on high quality evidence-based medicine and most have included useful tables summarizing seminal trials and available resources. Copyright © 2017 Elsevier Inc. All rights reserved.

Digital image archiving: challenges and choices.

PubMed

Dumery, Barbara

2002-01-01

In the last five years, imaging exam volume has grown rapidly. In addition to increased image acquisition, there is more patient information per study. RIS-PACS integration and information-rich DICOM headers now provide us with more patient information relative to each study. The volume of archived digital images is increasing and will continue to rise at a steeper incline than film-based storage of the past. Many filmless facilities have been caught off guard by this increase, which has been stimulated by many factors. The most significant factor is investment in new digital and DICOM-compliant modalities. A huge volume driver is the increase in images per study from multi-slice technology. Storage requirements also are affected by disaster recovery initiatives and state retention mandates. This burgeoning rate of imaging data volume presents many challenges: cost of ownership, data accessibility, storage media obsolescence, database considerations, physical limitations, reliability and redundancy. There are two basic approaches to archiving--single tier and multi-tier. Each has benefits. With a single-tier approach, all the data is stored on a single media that can be accessed very quickly. A redundant copy of the data is then stored onto another less expensive media. This is usually a removable media. In this approach, the on-line storage is increased incrementally as volume grows. In a multi-tier approach, storage levels are set up based on access speed and cost. In other words, all images are stored at the deepest archiving level, which is also the least expensive. Images are stored on or moved back to the intermediate and on-line levels if they will need to be accessed more quickly. It can be difficult to decide what the best approach is for your organization. The options include RAIDs (redundant array of independent disks), direct attached RAID storage (DAS), network storage using RAIDs (NAS and SAN), removable media such as different types of tape, compact disks (CDs and DVDs) and magneto-optical disks (MODs). As you evaluate the various options for storage, it is important to consider both performance and cost. For most imaging enterprises, a single-tier archiving approach is the best solution. With the cost of hard drives declining, NAS is a very feasible solution today. It is highly reliable, offers immediate access to all exams, and easily scales as imaging volume grows. Best of all, media obsolescence challenges need not be of concern. For back-up storage, removable media can be implemented, with a smaller investment needed as it will only be used for a redundant copy of the data. There is no need to keep it online and available. If further system redundancy is desired, multiple servers should be considered. The multi-tier approach still has its merits for smaller enterprises, but with a detailed long-term cost of ownership analysis, NAS will probably still come out on top as the solution of choice for many imaging facilities.

Joint Peru/United States report on Peru/United States cooperative energy assessment. Volume 4 of 4 Volumes Annexes 8-11

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1979-08-01

A comprehensive assessment of the biofuel potential of Peru is presented. Topics discussed cover current biofuel utilization practices; evaluation of Peruvian biomass productivity; identification of Peruvian agricultural and forestry resources; assessment of resource development and management concerns; identification of market considerations; description of biofuel technological options; and regional identification of biofuel technology applications. The discussion of current biofuel utilization centers on a qualitative description of the main conversion approaches now being practiced in Peru. Biomass productivity is evaluated in the context of the terrain, soil, and climatic conditions found in Peru. A quantitative description of the energy potential that couldmore » be realized from agricultural and forestry resources of Peru follows. A regional picture is given for the production of agricultural residues and forest resources that could potentially supply energy. The assessment of resource development and management concerns focuses on harvesting, reforestation, training, and the environmental consequences of utilization of forest resources. Market factors assessed include: importation, internal market development, external market development, energy policy and pricing, and transportation. Ten biofuel technology options for Peru were identified: small- to medium-scale gasification, a wood waste inventory, stationary and mobile charcoal production systems, wood distillation, forest resource development and management, electrical cogeneration, anaerobic digestion technology, development of ethanol production capabilities, and agricultural strategies for fuel production.Based upon these biofuel options, nine applications were identified for the Costa Region, eight for the Sierra Region, and ten for the Selva Region.« less

Dosimetric benefits of IMRT and VMAT in the treatment of middle thoracic esophageal cancer: is the conformal radiotherapy still an alternative option?

PubMed

Wu, Zhiqin; Xie, Congying; Hu, Meilong; Han, Ce; Yi, Jinling; Zhou, Yongqiang; Yuan, Huawei; Jin, Xiance

2014-05-08

The purpose of this study is to investigate the dosimetric differences among conformal radiotherapy (CRT), intensity-modulated radiotherapy (IMRT), and volumetric-modulated radiotherapy (VMAT) in the treatment of middle thoracic esophageal cancer, and determine the most appropriate treatment modality. IMRT and one-arc VMAT plans were generated for eight middle thoracic esophageal cancer patients treated previous with CRT. The planning target volume (PTV) coverage and protections on organs at risk of three planning schemes were compared. All plans have sufficient PTV coverage and no significant differences were observed, except for the conformity and homogeneity. The lung V5, V10, and V13 in CRT were 47.9% ± 6.1%, 36.5% ± 4.6%, and 33.2% ± 4.2%, respectively, which were greatly increased to 78.2% ± 13.7% (p < 0.01), 80.8% ± 14.9% (p < 0.01), 48.4% ± 8.2% (p = 0.05) in IMRT and 58.6% ± 10.5% (p = 0.03), 67.7% ± 14.0% (p < 0.01), and 53.0% ± 10.1% (p < 0.01) in VMAT, respectively. The lung V20 (p = 0.03) in VMAT and the V30 (p = 0.04) in IMRT were lower than those in CRT. Both IMRT and VMAT achieved a better protection on heart. However, the volumes of the healthy tissue outside of PTV irradiated by a low dose were higher for IMRT and VMAT. IMRT and VMAT also had a higher MU, optimization time, and delivery time compared to CRT. In conclusion, all CRT, IMRT, and VMAT plans are able to meet the prescription and there is no clear distinction on PTV coverage. IMRT and VMAT can only decrease the volume of lung and heart receiving a high dose, but at a cost of delivering low dose to more volume of lung and normal tissues. CRT is still a feasible option for middle thoracic esophageal cancer radiotherapy, especially for the cost-effective consideration.

Space station systems technology study (add-on task). Volume 2: Trade study and technology selection

NASA Technical Reports Server (NTRS)

1985-01-01

The current Space Station Systems Technology Study add on task was an outgrowth of the Advanced Platform Systems Technology Study (APSTS) that was completed in April 1983 and the subsequent Space Station System Technology Study completed in April 1984. The first APSTS proceeded from the identification of 106 technology topics to the selection of five for detailed trade studies. During the advanced platform study, the technical issues and options were evaluated through detailed trade processes, individual consideration was given to costs and benefits for the technologies identified for advancement, and advancement plans were developed. An approach similar to that was used in the subsequent study, with emphasis on system definition in four specific technology areas to facilitate a more in depth analysis of technology issues.

Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure.

PubMed

Ishikawa, Kiyotake; Fish, Kenneth M; Tilemann, Lisa; Rapti, Kleopatra; Aguero, Jaume; Santos-Gallego, Carlos G; Lee, Ahyoung; Karakikes, Ioannis; Xie, Chaoqin; Akar, Fadi G; Shimada, Yuichi J; Gwathmey, Judith K; Asokan, Aravind; McPhee, Scott; Samulski, Jade; Samulski, Richard Jude; Sigg, Daniel C; Weber, Thomas; Kranias, Evangelia G; Hajjar, Roger J

2014-12-01

Cardiac gene therapy has emerged as a promising option to treat advanced heart failure (HF). Advances in molecular biology and gene targeting approaches are offering further novel options for genetic manipulation of the cardiovascular system. The aim of this study was to improve cardiac function in chronic HF by overexpressing constitutively active inhibitor-1 (I-1c) using a novel cardiotropic vector generated by capsid reengineering of adeno-associated virus (BNP116). One month after a large anterior myocardial infarction, 20 Yorkshire pigs randomly received intracoronary injection of either high-dose BNP116.I-1c (1.0 × 10(13) vector genomes (vg), n = 7), low-dose BNP116.I-1c (3.0 × 10(12) vg, n = 7), or saline (n = 6). Compared to baseline, mean left ventricular ejection fraction increased by 5.7% in the high-dose group, and by 5.2% in the low-dose group, whereas it decreased by 7% in the saline group. Additionally, preload-recruitable stroke work obtained from pressure-volume analysis demonstrated significantly higher cardiac performance in the high-dose group. Likewise, other hemodynamic parameters, including stroke volume and contractility index indicated improved cardiac function after the I-1c gene transfer. Furthermore, BNP116 showed a favorable gene expression pattern for targeting the heart. In summary, I-1c overexpression using BNP116 improves cardiac function in a clinically relevant model of ischemic HF.

Cardiac I-1c Overexpression With Reengineered AAV Improves Cardiac Function in Swine Ischemic Heart Failure

PubMed Central

Ishikawa, Kiyotake; Fish, Kenneth M; Tilemann, Lisa; Rapti, Kleopatra; Aguero, Jaume; Santos-Gallego, Carlos G; Lee, Ahyoung; Karakikes, Ioannis; Xie, Chaoqin; Akar, Fadi G; Shimada, Yuichi J; Gwathmey, Judith K; Asokan, Aravind; McPhee, Scott; Samulski, Jade; Samulski, Richard Jude; Sigg, Daniel C; Weber, Thomas; Kranias, Evangelia G; Hajjar, Roger J

2014-01-01

Cardiac gene therapy has emerged as a promising option to treat advanced heart failure (HF). Advances in molecular biology and gene targeting approaches are offering further novel options for genetic manipulation of the cardiovascular system. The aim of this study was to improve cardiac function in chronic HF by overexpressing constitutively active inhibitor-1 (I-1c) using a novel cardiotropic vector generated by capsid reengineering of adeno-associated virus (BNP116). One month after a large anterior myocardial infarction, 20 Yorkshire pigs randomly received intracoronary injection of either high-dose BNP116.I-1c (1.0 × 1013 vector genomes (vg), n = 7), low-dose BNP116.I-1c (3.0 × 1012 vg, n = 7), or saline (n = 6). Compared to baseline, mean left ventricular ejection fraction increased by 5.7% in the high-dose group, and by 5.2% in the low-dose group, whereas it decreased by 7% in the saline group. Additionally, preload-recruitable stroke work obtained from pressure–volume analysis demonstrated significantly higher cardiac performance in the high-dose group. Likewise, other hemodynamic parameters, including stroke volume and contractility index indicated improved cardiac function after the I-1c gene transfer. Furthermore, BNP116 showed a favorable gene expression pattern for targeting the heart. In summary, I-1c overexpression using BNP116 improves cardiac function in a clinically relevant model of ischemic HF. PMID:25023328

Orbiting Deep Space Relay Station (ODSRS). Volume 1: Requirement determination

NASA Technical Reports Server (NTRS)

Hunter, J. A.

1979-01-01

The deep space communications requirements of the post-1985 time frame are described and the orbiting deep space relay station (ODSRS) is presented as an option for meeting these requirements. Under current conditions, the ODSRS is not yet cost competitive with Earth based stations to increase DSN telemetry performance, but has significant advantages over a ground station, and these are sufficient to maintain it as a future option. These advantages include: the ability to track a spacecraft 24 hours per day with ground stations located only in the USA; the ability to operate at higher frequencies that would be attenuated by Earth's atmosphere; and the potential for building very large structures without the constraints of Earth's gravity.

The Effects of Meditation on Grey Matter Atrophy and Neurodegeneration: A Systematic Review.

PubMed

Last, Nicole; Tufts, Emily; Auger, Leslie E

2017-01-01

The present systematic review is based on the premise that a variety of neurodegenerative diseases are accompanied by grey matter atrophy in the brain and meditation may impact this. Given that age is a major risk factor for many of these progressive and neurodegenerative diseases and that the percentage of the population over the age of 65 is quickly increasing, there is an obvious need for prompt treatment and prevention advances in research. As there is currently no cure for Alzheimer's disease and other neurodegenerative diseases, many are seeking non-pharmacological treatment options in attempts to offset the disease-related cognitive and functional declines. On the basis of a growing body of research suggesting that meditation is effective in increasing grey matter volume in healthy participants, this paper systematically reviewed the literature regarding the effects of meditation on restoring grey matter volume in healthy individuals and those affected by neurodegeneration. This review searched PubMed, CINAHL, and APA PsycNET to identify original studies that included MRI imaging to measure grey matter volume in meditators and post-mindfulness-based intervention participants compared to controls. Thirteen studies were considered eligible for review and involved a wide variety of meditation techniques and included participants with and without cognitive impairment. All studies reported significant increases in grey matter volume in the meditators/intervention group, albeit in assorted regions of the brain. Limited research exists on the mechanisms through which meditation affects disease-related neurodegeneration, but preliminary evidence suggests that it may offset grey matter atrophy.

Review of Education and Training for Officers (RETO). Volume 1. An Overview.

DTIC Science & Technology

1978-06-30

instruction is delayed until after graduation. Procurement managers would be in USAREC as in the Platoon Leader Course option. Low costs, large market ...military competency. The Office of Management and Budget complicated matters by asserting that too-many resources were being devoted to Officer...the Picture .................. .............. IX-) Management of Officers ................ .. ........ X-1 Recommendations

Religious Education and Peace: An Overview and Response

ERIC Educational Resources Information Center

King, Ursula

2007-01-01

This article provides some concluding reflections on religious education and peace-making in different countries in East and West (Indonesia, Korea, Japan, Israel, Spain, Germany, USA), as discussed in the previous papers of this volume. I mention the changed nature of modern forms of violence and war, so that peace is no longer just an option in…

Small-diameter roundwood, strong-post W-beam guardrail systems

Treesearch

David Kretschmann; Ronald Faller; John Reid; Jason Hascall; Dean Sicking; John Rohde

2006-01-01

Round guardrail posts may provide an important value-added option for small-diameter thinnings. Such posts require minimum processing and are believed to have higher strength for the equivalent rectangular volume. The resulting value-added product may bring a higher return compared to lumber. The obstacles to immediate utilization of ponderosa pine and Douglas-fir...

Community Schools in Ohio: Implementation Issues and Impact on Ohio's Education System. Volume I.

ERIC Educational Resources Information Center

Ohio State Legislative Office of Education Oversight, Columbus.

Community schools were created in Ohio to provide additional educational options for children in low-performing schools and to develop innovative teaching and management techniques that may be transferable to traditional public schools. In 1997 the Ohio General Assembly required the Legislative Office of Education Oversight (LOEO) to evaluate the…

Solid rocket booster performance evaluation model. Volume 2: Users manual

NASA Technical Reports Server (NTRS)

1974-01-01

This users manual for the solid rocket booster performance evaluation model (SRB-II) contains descriptions of the model, the program options, the required program inputs, the program output format and the program error messages. SRB-II is written in FORTRAN and is operational on both the IBM 370/155 and the MSFC UNIVAC 1108 computers.

Helicopter technology benefits and needs. Volume 1: Summary

NASA Technical Reports Server (NTRS)

Zuk, J.; Adams, R. J.

1980-01-01

Present public service helicopter benefits and the potential benefits of an advanced public service rotorcraft (200 knots to 300 knots) are summarized. Past and future public service growth is quantified and assessed and needs, problem areas, and desired vehicle characteristics are defined. Research and technology recommendations are formulated and the costs and benefits of research options are assessed.

Sourcebook for English Teachers: Directed Reading/Teaching Guides for Selected Literacy Works. Volume 2.

ERIC Educational Resources Information Center

Ley, Terry C., Ed.

This sourcebook presents reading guides for 27 literary works frequently used by secondary school English teachers. The guides contain an overview of the work, a pool of instructional objectives for each work, a variety of activities, a series of discussion options, suggestions for evaluation, and annotated lists of related works. Included are:…

Space Station needs, attributes and architectural options, volume 2, book 2, part 4: International reports

NASA Technical Reports Server (NTRS)

1983-01-01

The capabilities of the European Space Agency's SPAS and EURECA platforms for reference payload accommodation are considered. The instrument pointing subsystem, the position and hold mount, and the antenna pointing mechanism developed by Dornier are described. Relevant payloads for the space station are summarized and space station accommodation aspects are discussed.

How to recover more value from small pine trees: Essential oils and resins

Treesearch

Vasant M. Kelkar; Brian W. Geils; Dennis R. Becker; Steven T. Overby; Daniel G. Neary

2006-01-01

In recent years, the young dense forests of northern Arizona have suffered extreme droughts, wildfires, and insect outbreaks. Improving forest health requires reducing forest density by cutting many small-diameter trees with the consequent production of large volumes of residual biomass. To offset the cost of handling this low-value timber, additional marketing options...

Sourcebook for English Teachers: Directed Reading/Teaching Guides for Selected Literary Works. Volume 1.

ERIC Educational Resources Information Center

Ley, Terry C., Ed.

This sourcebook presents reading guides for 22 literary works frequently used by secondary school English teachers. The guides contain an overview of the work, a pool of instructional objectives for each work, a variety of activities, a series of discussion options, suggestions for evaluation, and annotated lists of related works. Included are:…

Space station needs, attributes and architectural options. Volume 3, attachment 1, task 1: Mission requirements

NASA Technical Reports Server (NTRS)

1983-01-01

The development and systems architectural requirements of the space station program are described. The system design is determined by user requirements. Investigated topics include physical and life science experiments, commercial utilization, U.S. national security, and remote space operations. The economic impact of the space station program is analyzed.

Urban America: Policy Choices for Los Angeles and the Nation.

ERIC Educational Resources Information Center

Steinberg, James B., Ed.; And Others

This volume presents 13 essays on urban problems in the United States, particularly in Los Angeles (California) following the 1992 riots, and policy options for the future. Part 1 addresses policies of the past three decades; Part 2 looks at children, youth, and families; Part 3 discusses crime and criminal justice; and Part 4 examines public…

40 CFR 86.1823-08 - Durability demonstration procedures for exhaust emissions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES (CONTINUED) General Compliance Provisions for Control of Air Pollution From New and In... volume test groups may optionally meet the requirements of §§ 86.1838-01 and 86.1826-01 in lieu of the...

Editorial Research Reports on the Scientific Society.

ERIC Educational Resources Information Center

Dickinson, William B., Jr., Ed.

Nine reports published in this volume reflect upon the scientific revolution of the 20th century. Technological and scientific achievements are reviewed in the light of changes they have caused in human life. The challenge put forth is whether man can use wisely the new world of options that science opens for him. In this perspective the reports…

Education in Austerity: Options for Planners. Fundamentals for Planning 36.

ERIC Educational Resources Information Center

Lewin, Keith M.

This book explores the issues raised by the changing climate within which educational planning will take place in the final years of the 20th century. The volume focuses on the problems faced by countries hardest hit by economic recession and the need for adjustment to a changing economic environment. Organized into six chapters, the book…

Oscar's Options: A Supplementary Environmental Education Curriculum. Books 1 and 2 (Combined).

ERIC Educational Resources Information Center

Bell, Carole O.; Schwartz, Martha M.

This two-volume supplementary curriculum is designed for teachers of children grades 4-8. There are eight units overall: (1) national resources; (2) litter; (3) household hazardous wastes; (4) landfills; (5) recycling; (6) incineration; (7) compost; and (8) source reduction. Each unit contains a list of objectives for students, a suggested time…

New features added to EVALIDator: ratio estimation and county choropleth maps

Treesearch

Patrick D. Miles; Mark H. Hansen

2012-01-01

The EVALIDator Web application, developed in 2007, provides estimates and sampling errors for many user selected forest statistics from the Forest Inventory and Analysis Database (FIADB). Among the statistics estimated are forest area, number of trees, biomass, volume, growth, removals, and mortality. A new release of EVALIDator, developed in 2012, has an option to...

Sourcebook for English Teachers: Directed Reading/Teaching Guides for Selected Literacy Works. Volume 3.

ERIC Educational Resources Information Center

Ley, Terry C., Ed.

This sourcebook presents reading guides for 39 literary works frequently used by scondary school English teachers. The guides contain an overview of the work, a pool of instructional objectives for each work, a variety of activities, a series of discussion options, suggestions for evaluation, and annotated lists of related works. Included are:…

Imputatoin and Model-Based Updating Technique for Annual Forest Inventories

Treesearch

Ronald E. McRoberts

2001-01-01

The USDA Forest Service is developing an annual inventory system to establish the capability of producing annual estimates of timber volume and related variables. The inventory system features measurement of an annual sample of field plots with options for updating data for plots measured in previous years. One imputation and two model-based updating techniques are...

Space station (modular) mission analysis. Volume 1: Mission analysis

NASA Technical Reports Server (NTRS)

1971-01-01

The mission analysis on the modular space station considers experimental requirements and options characterized by low initial cost and incremental manning. Features that affect initial development and early operating costs are identified and their impacts on the program are assessed. Considered are the areas of experiment, mission, operations, information management, and long life and safety analyses.

Technology assessment of future intercity passenger transporation systems. Volume 1: Summary report

NASA Technical Reports Server (NTRS)

1976-01-01

Technical, economic, environmental, and sociopolitical issues associated with future intercity transportation system options were assured. Technology assessment was used as a tool to assist in the identification of basic research and technology development tasks that should be undertaken. The emphasis was on domestic passenger transportation, but interfaces with freight and international transportation were considered.

Space station needs, attributes and architectural options. Volume 3, task 1: Mission requirements

NASA Technical Reports Server (NTRS)

1983-01-01

The mission requirements of the space station program are investigated. Mission parameters are divided into user support from private industry, scientific experimentation, U.S. national security, and space operations away from the space station. These categories define the design and use of the space station. An analysis of cost estimates is included.

Manufacturing Methods for Cutting, Machining and Drilling Composites. Volume 1. Composites Machining Handbook

DTIC Science & Technology

1978-08-01

12°±30’ 1180±2° OPTIONAL .0005 IN./IN. BACK TAPER 015 RAD LIPS TO BE WITHIN .002 OF TRUE ANGULAR POSITION NOTES: 1. LAND WIDTH: 28% ± .005... horoscope and dye-penetrant requirements. 79 PHASE 1 PHASE II PHASE III PHASE IV CUTTING DRILLING MACHINING NONDESTRUCTIVE EVALUATION METHOD MATERIAL

Spelling Test Generator--Volume 1: English. [CD-ROM].

ERIC Educational Resources Information Center

Aud, Joel; DeWolfe, Rosemary; Gintz, Christopher; Griswold, Scott; Hefter, Richard; Lowery, Adam; Richards, Maureen; Yi, Song Choi

This software product makes the manipulation of the more than 3000 most commonly used words in the English language easy to select and manipulate into various activities for elementary and middle school students. Users of the program have a variety of options: the program can automatically select words based on their age/grade level, frequency of…

Developing a stochastic traffic volume prediction model for public-private partnership projects

NASA Astrophysics Data System (ADS)

Phong, Nguyen Thanh; Likhitruangsilp, Veerasak; Onishi, Masamitsu

2017-11-01

Transportation projects require an enormous amount of capital investment resulting from their tremendous size, complexity, and risk. Due to the limitation of public finances, the private sector is invited to participate in transportation project development. The private sector can entirely or partially invest in transportation projects in the form of Public-Private Partnership (PPP) scheme, which has been an attractive option for several developing countries, including Vietnam. There are many factors affecting the success of PPP projects. The accurate prediction of traffic volume is considered one of the key success factors of PPP transportation projects. However, only few research works investigated how to predict traffic volume over a long period of time. Moreover, conventional traffic volume forecasting methods are usually based on deterministic models which predict a single value of traffic volume but do not consider risk and uncertainty. This knowledge gap makes it difficult for concessionaires to estimate PPP transportation project revenues accurately. The objective of this paper is to develop a probabilistic traffic volume prediction model. First, traffic volumes were estimated following the Geometric Brownian Motion (GBM) process. Monte Carlo technique is then applied to simulate different scenarios. The results show that this stochastic approach can systematically analyze variations in the traffic volume and yield more reliable estimates for PPP projects.

Space shuttle system program definition. Volume 4: Cost and schedule report

NASA Technical Reports Server (NTRS)

1972-01-01

The supporting cost and schedule data for the second half of the Space Shuttle System Phase B Extension Study is summarized. The major objective for this period was to address the cost/schedule differences affecting final selection of the HO orbiter space shuttle system. The contending options under study included the following booster launch configurations: (1) series burn ballistic recoverable booster (BRB), (2) parallel burn ballistic recoverable booster (BRB), (3) series burn solid rocket motors (SRM's), and (4) parallel burn solid rocket motors (SRM's). The implications of varying payload bay sizes for the orbiter, engine type for the ballistics recoverable booster, and SRM motors for the solid booster were examined.

Evaluation of composting as a strategy for managing organic wastes from a municipal market in Nicaragua.

PubMed

Aulinas Masó, Montserrat; Bonmatí Blasi, August

2008-07-01

A pilot-scale study was undertaken to evaluate alternatives to the solid waste management of a Central American municipal market located in Estelí, Nicaragua. The municipal solid waste from the local market is the second largest contributor to the municipal solid waste (MSW) stream. Waste from the market without any previous sorting or treatment is open dumped. The options evaluated in this study were windrow composting, windrow composting with yard waste, bokashi and vermicompost. Significant differences between the properties of composts produced were found; however, all of them reduce the initial waste volume and are potential useful agronomic products for a survival agrarian milieu.

Conversion of transuranic waste to low level waste by decontamination: a technical and economic evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allen, R.P.; Hazelton, R.F.

1984-12-01

A study was conducted to evaluate the technical and economic feasibility of using in-situ decontamination techniques to convert glove boxes and other large TRU-contaminated components directly into LLW. The results of the technical evaluation indicate that in-situ decontamination of these types of components to non-TRU levels is technically feasible. Applicable decontamination techniques include electropolishing, hand scrubbing, chemical washes/sprays, strippable coatings and Freon spray-cleaning. The removal of contamination from crevices and other holdup areas remains a problem, but may be solved through further advances in decontamination technology. Also, the increase in the allowable maximum TRU level from 10 nCi/g to 100more » nCi/g as defined in DOE Order 5820.2 reduces the removal requirement and facilitates measurement of the remaining quantities. The major emphasis of the study was on a cost/benefit evaluation that included a review and update of previous analyses and evaluations of TRU-waste volume reduction and conversion options. The results of the economic evaluation show, for the assumptions used, that there is a definite cost incentive to size reduce large components, and that decontamination of sectioned material has become cost competitive with the size reduction options. In-situ decontamination appears to be the lowest cost option when based on routine-type operations conducted by well-trained and properly equipped personnel. 16 references, 1 figure, 7 tables.« less

Municipal solid waste management health risk assessment from air emissions for China by applying life cycle analysis.

PubMed

Li, Hua; Nitivattananon, Vilas; Li, Peng

2015-05-01

This study is to quantify and objectively evaluate the extent of environmental health risks from three waste treatment options suggested by the national municipal solid waste management enhancing strategy (No [2011] 9 of the State Council, promulgated on 19 April 2011), which includes sanitary landfill, waste-to-energy incineration and compost, together with the material recovery facility through a case study in Zhangqiu City of China. It addresses potential chronic health risks from air emissions to residential receptors in the impacted area. It combines field survey, analogue survey, design documents and life cycle inventory methods in defining the source strength of chemicals of potential concern. The modelling of life cycle inventory and air dispersion is via integrated waste management(IWM)-2 and Screening Air Dispersion Model (Version 3.0) (SCREEN3). The health risk assessment is in accordance with United States Environmental Protection Agency guidance Risk Assessment Guidance for Superfund (RAGS), Volume I: Human Health Evaluation Manual (Part F, Supplemental Guidance for Inhalation Risk Assessment). The exposure concentration is based on long-term exposure to the maximum ground level contaminant in air under the 'reasonable worst situation' emissions and then directly compared with reference for concentration and unit risk factor/cancer slope factor derived from the national air quality standard (for a conventional pollutant) and toxicological studies (for a specific pollutant). Results from this study suggest that the option of compost with material recovery facility treatment may pose less negative health impacts than other options; the sensitivity analysis shows that the landfill integrated waste management collection rate has a great influence on the impact results. Further investigation is needed to validate or challenge the findings of this study. © The Author(s) 2015.

Single-session radiofrequency ablation on benign thyroid nodules: a prospective single center study : Radiofrequency ablation on thyroid.

PubMed

Aysan, Erhan; Idiz, Ufuk Oguz; Akbulut, Huseyin; Elmas, Leyla

2016-05-01

The activity of the application of single-session ultrasonography (US)-guided percutaneous radio frequency ablation (RFA) in benign thyroid nodules was investigated in this prospective clinical study. RFA treatment was applied to 100 nodules in 100 patients (78 women, 22 men; average age 44.5 years old; age range 18-71) who had euthyroid condition, nodule size larger than 1 cm in the ultrasonography, proven to be benign by fine needle aspiration cytology. The nodules were separated into three groups according to the content: solid, cystic and mixed. In first 73 cases, the process performed under local anesthesia and the other 27 cases were performed under general anesthesia. RFA process was standardized to 70 W in all of the patients, and a moving shot technique was used. The results acquired in the third and sixth months of the controls were evaluated, and the volume of the nodules was screened. No differences between the thyroid function tests performed before and after RFA were detected (p > 0.05). The mean volume of the nodules before the process, in the third month after the process, and in the sixth month were 16.8, 4.8, and 2.6 ml, respectively (p < 0.001). The decrease in cystic nodules was greater than solid and mixed structures. Temporary hoarseness occurred in one case and skin edema was detected in a patient at the isthmus. RFA is an option for treatment, with minimal invasiveness and a low complication rate, and it is effective primarily in cases with benign nodules and nodular goiter. In cases with good compliance, the likelihood of success is greater. General anesthesia can be a good option for anxious cases to gather better results.

Solar power satellite system definition study. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1979-01-01

Configuration concepts, option sizes, and systems definitions study design evolutions are reviewed. The main features of the present reference design silicon solar cell solar power satellite are described, as well as the provisions for space construction and support systems. The principal study accomplishments and conclusions are summarized according to the following tasks: (1) baseline critique; (2) construction and maintenance; (3) industrial complex needs, cost estimates, and production capacity; (4) launch complex requirements at KSC or at an offshore facility; (5) integration of the SPS/ground power network; (6) technology advancement and development; (7) costs and schedules; and (8) exploratory technology: laser annealing of solar cells degraded by proton irradiation, and a fiber-optic phase distribution link at 980 MHz.

Rocket Based Combined Cycle (RBCC) Propulsion Workshop, volume 2

NASA Technical Reports Server (NTRS)

Chojnacki, Kent T.

1992-01-01

The goal of the Rocket Based Combined Cycle (RBCC) Propulsion Technology Workshop, was to impart technology information to the propulsion community with respect to hypersonic combined cycle propulsion capabilities. The major recommendation resulting from this technology workshop was as follows: conduct a systems-level applications study to define the desired propulsion system and vehicle technology requirements for LEO launch vehicles. All SSTO and TSTO options using the various propulsion systems (airbreathing combined cycle, rocket-based combined cycle, and all rocket) must be considered. Such a study should be accomplished as soon as possible. It must be conducted with a consistent set of ground rules and assumptions. Additionally, the study should be conducted before any major expenditures on a RBCC technology development program occur.

Analysis of space systems for the space disposal of nuclear waste follow-on study. Volume 2: Technical report

NASA Technical Reports Server (NTRS)

1982-01-01

The space option for disposal of certain high-level nuclear wastes in space as a complement to mined geological repositories is studied. A brief overview of the study background, scope, objective, guidelines and assumptions, and contents is presented. The determination of the effects of variations in the waste mix on the space systems concept to allow determination of the space systems effect on total system risk benefits when used as a complement to the DOE reference mined geological repository is studied. The waste payload system, launch site, launch system, and orbit transfer system are all addressed. Rescue mission requirements are studied. The characteristics of waste forms suitable for space disposal are identified. Trajectories and performance requirements are discussed.

Outcomes of Fat-Augmented Latissimus Dorsi (FALD) Flap Versus Implant-Based Latissimus Dorsi Flap for Delayed Post-radiation Breast Reconstruction.

PubMed

Demiri, Efterpi C; Dionyssiou, Dimitrios D; Tsimponis, Antonios; Goula, Christina-Olga; Pavlidis, Leonidas C; Spyropoulou, Georgia-Alexandra

2018-06-01

Although free abdominal flaps constitute the gold standard in post-radiation delayed breast reconstruction, latissimus dorsi-based methods offer alternative reconstructive options. This retrospective study aims to compare outcomes of delayed breast reconstruction using the fat-augmented latissimus dorsi (FALD) autologous reconstruction and the latissimus dorsi-plus-implant reconstruction in irradiated women. We reviewed the files of 47 post-mastectomy irradiated patients (aged 29-73 years), who underwent delayed latissimus dorsi-based breast reconstruction between 2010 and 2016. Twenty-three patients (Group A) had an extended FALD flap and twenty-four patients (Group B) an implant-based latissimus dorsi reconstruction. Patients' age, BMI, pregnancies, volume of injected fat, implant size, postoperative complications, and secondary surgical procedures were recorded and analyzed. Age, BMI, pregnancies, and donor-site complications were similar in both groups (p > 0.05). Mean fat volume injected initially was 254 cc (ranged 130-380 cc/session); mean implant volume was 323 cc (ranged 225-420 cc). Breast complications were significantly fewer in Group A (one wound dehiscence, two oily cysts) compared to Group B (three cases with wound dehiscence, two extrusions, thirteen severe capsular contractions). Non-statistically significant difference was documented for secondary procedures between groups; although the mean number of additional surgeries/patient was higher in Group A, they referred to secondary lipofilling, whereas in Group B they were revision surgeries for complications. The FALD flap constitutes an alternative method for delayed autologous reconstruction after post-mastectomy irradiation, avoiding implant-related complications. Although additional fat graft sessions might be required, it provides an ideal autogenous reconstructive option for thin nulliparous women, with a small opposite breast and adequate fat donor sites. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Endoscopic lung volume reduction coil treatment in patients with chronic hypercapnic respiratory failure: an observational study.

PubMed

Simon, Marcel; Harbaum, Lars; Oqueka, Tim; Kluge, Stefan; Klose, Hans

2017-01-01

Endoscopic lung volume reduction coil (LVRC) treatment is an option for selected patients with severe emphysema. In the advanced stages, emphysema leads to respiratory failure: hypoxemia and eventually chronic hypercapnic respiratory failure. It can be hypothesized that LVRC treatment, a procedure targeting hyperinflation and thereby reducing ventilatory workload, may be especially beneficial in patients with chronic hypercapnic respiratory failure. This study was conducted to gain first insights into the effects and the safety of LVRC treatment in patients with emphysema and chronic hypercapnic respiratory failure. A retrospective observational study conducted in the Department of Respiratory Medicine at the University Medical Center Hamburg-Eppendorf, Germany on all patients with chronic hypercapnic respiratory failure in whom bilateral LVRC treatment was performed between 1 April 2012 and 30 September 2015. During the study period, bilateral LVRC treatment was performed in 10 patients with chronic hypercapnic respiratory failure. Compared with baseline, bilateral LVRC treatment led to a significant increase in mean forced expiratory volume in one second (FEV 1 ) from 0.5 ± 0.1 l to 0.6 ± 0.2 l ( p = 0.004), a decrease in residual volume (RV) from 6.1 ± 0.9 l to 5.6 ± 1.1 l ( p = 0.02) and a reduction in partial pressure of carbon dioxide in arterial blood (PaCO 2 ) from 53 ± 5 mmHg to 48 ± 4 mmHg ( p = 0.03). One case of hemoptysis requiring readmission to hospital was the only severe adverse event. LVRC treatment was safe and effective in patients with nonsevere chronic hypercapnic respiratory failure. It led not only to an improvement in lung function but also to a significant decrease in PaCO 2 .

Endoscopic peroral jejunal fecal microbiota transplantation.

PubMed

Link, Alexander; Lachmund, Tim; Schulz, Christian; Weigt, Jochen; Malfertheiner, Peter

2016-11-01

Fecal microbiota transplantation (FMT) is a valuable treatment modality for recurrent Clostridium difficile (C. difficile) colitis. Multiple questions including the best delivery route and volume remain unanswered. Here, we report a case series of high-volume FMT using endoscopic jejunal application route. In prospective observational study, FMT was performed using fresh specimen from healthy unrelated donors to the patients with recurrent or refractory C. difficile colitis. Selection of the route was based on the patient's preferences. Specimens of at least 50g were dissolved in 500ml of electrolyte solution and administered using endoscope directly in jejunum. All procedures led to cure of C. difficile colitis. With exception of one case the procedure was well tolerated. In two cases, we observed FMT-reflux into the stomach despite deep jejunal application and in single case the FMT-reflux led to tracheal aspiration and severe pneumonia. High-volume FMT via endoscopic jejunal route is an effective treatment option that is well tolerated and easy to perform. Nevertheless, aspiration is potential life-threatening event that needs to be kept in mind during the FMT-procedure. Copyright © 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Bone histomorphometry using free and commonly available software.

PubMed

Egan, Kevin P; Brennan, Tracy A; Pignolo, Robert J

2012-12-01

Histomorphometric analysis is a widely used technique to assess changes in tissue structure and function. Commercially available programs that measure histomorphometric parameters can be cost-prohibitive. In this study, we compared an inexpensive method of histomorphometry to a current proprietary software program. Image J and Adobe Photoshop(®) were used to measure static and kinetic bone histomorphometric parameters. Photomicrographs of Goldner's trichrome-stained femurs were used to generate black-and-white image masks, representing bone and non-bone tissue, respectively, in Adobe Photoshop(®) . The masks were used to quantify histomorphometric parameters (bone volume, tissue volume, osteoid volume, mineralizing surface and interlabel width) in Image J. The resultant values obtained using Image J and the proprietary software were compared and differences found to be statistically non-significant. The wide-ranging use of histomorphometric analysis for assessing the basic morphology of tissue components makes it important to have affordable and accurate measurement options available for a diverse range of applications. Here we have developed and validated an approach to histomorphometry using commonly and freely available software that is comparable to a much more costly, commercially available software program. © 2012 Blackwell Publishing Limited.

Bone histomorphometry using free and commonly available software

PubMed Central

Egan, Kevin P.; Brennan, Tracy A.; Pignolo, Robert J.

2012-01-01

Aims Histomorphometric analysis is a widely used technique to assess changes in tissue structure and function. Commercially-available programs that measure histomorphometric parameters can be cost prohibitive. In this study, we compared an inexpensive method of histomorphometry to a current proprietary software program. Methods and results Image J and Adobe Photoshop® were used to measure static and kinetic bone histomorphometric parameters. Photomicrographs of Goldner’s Trichrome stained femurs were used to generate black and white image masks, representing bone and non-bone tissue, respectively, in Adobe Photoshop®. The masks were used to quantify histomorphometric parameters (bone volume, tissue volume, osteoid volume, mineralizing surface, and interlabel width) in Image J. The resultant values obtained using Image J and the proprietary software were compared and found to be statistically non-significant. Conclusions The wide ranging use of histomorphometric analysis for assessing the basic morphology of tissue components makes it important to have affordable and accurate measurement options that are available for a diverse range of applications. Here we have developed and validated an approach to histomorphometry using commonly and freely available software that is comparable to a much more costly, commercially-available software program. PMID:22882309

The use of OK-432 to prevent seroma in extended latissimus dorsi flap donor site after breast reconstruction.

PubMed

Yang, Yinlong; Chen, Yizuo; Qu, Jinmiao; Zhang, Xiaohua; Pan, Yifei

2015-01-01

The extended latissimus dorsi (LD) flap has become a preferred method of breast reconstruction. However, donor site seroma is the most common complication of LD flap reconstruction. The purpose of this study was to investigate the effectiveness of OK-432 on postoperative drainage and seroma formation in the site of the LD myocutaneous flap donor site. A retrospective study was conducted on 49 patients who underwent immediate breast reconstruction with extended LD flaps between July 2008 and September 2013. The patients received either OK-432 (OK-432 group, n = 24) or not (control group, n = 25) in the extended LD donor site. Outcome measures were obtained from the incidence and volume of postoperative seroma, total volume of back drains, the total drainage, indwelling period of drainage, and frequency of aspiration. There were no statistically significant differences between the two groups in terms of age, body mass index, and flap size. The incidence of seroma was 41.7% in the OK-432 group and 72% in the control group (P = 0.032). There were also significant reductions in volume of postoperative seroma (P = 0.021), total drainage volume (P < 0.001), total volume of back drains (P < 0.001), indwelling period of drainage (P = 0.004), and frequency of aspiration (P = 0.008). The use of OK-432 is a feasible option for the reduction or prevention of seroma formation at the donor site in patients undergoing immediate breast reconstruction using a LD myocutaneous flap for breast cancer. Copyright © 2015 Elsevier Inc. All rights reserved.

Engineering assessment of inactive uranium mill tailings, Gunnison Site, Gunnison, Colorado. Phase II, Title I

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1977-11-01

Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Gunnison, Colorado. The Phase II - Title I services include the preparation of topographic measurements sufficient to determine areas and volumes of tailings and other radium-contaminated materials, the evaluation of resulting radiation exposures of individuals and nearby populations, the investigation of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. Radon gas release from the 0.5 million tons of tailings at the Gunnison site constitutes the most significant environmental impact, although windblownmore » tailings and external gamma radiation are also factors. The nine alternative actions presented range from millsite decontamination (Option I), to adding various depths of stabilization cover material (Options II and III), to removal of the tailings to long-term storage sites and decontamination of the present site (Options IV through IX). Cost estimates for the nine options range from $480,000 to $5,890,000. Reprocessing the tailings for uranium does not appear to be economically attractive at present.« less

Chronic obstructive pulmonary disease--a treatable disease.

PubMed

Osthoff, Mirjam; Jenkins, Christine; Leuppi, Jörg D

2013-04-11

Chronic obstructive pulmonary disease (COPD) is a global health challenge and a leading cause of death worldwide. Several risk factors have been identified, with cigarette smoking being the most important. Diagnostic assessment is based on symptoms, risk of exacerbations and results of lung function testing. A fixed post-bronchodilator ratio for forced expiratory volume in one second to forced expiratory volume (FEV1/FVC) of <0.7 is required to make the diagnosis, and the severity of airflow obstruction defines the grade according to GOLD (Global Strategy for the Diagnosis, Management, and Prevention of COPD). The GOLD strategy makes therapeutic recommendations taking into account the grade, symptomatic assessment and future risk of exacerbations. This review focuses on the therapeutic options for COPD, in accordance with the GOLD strategy. Smoking cessation is the most effective treatment option in all COPD stages. Bronchodilators, namely long-acting antimuscarinic drugs and long-acting beta-agonists, form the mainstay of treatment in COPD. Patients with frequent exacerbations also benefited from the addition of inhaled corticosteroids. Roflumilast is an add-on option for patients with severe COPD. Several controversies are the subject of discussion: (1.) whether pharmacotherapy can modify the natural history of COPD; (2.) whether pharmacotherapy should be started in the early stages of COPD; (3.) the impact of therapy on comorbidities; (4.) whether patients benefit from a combination therapy with a long-acting beta-agonist, a long-acting antimuscarinic drug and an inhaled corticosteroid; (5.) step-down therapy. This overview also reviews the evidence for recommended vaccines in COPD, as well as nonpharmacological therapies. Rehabilitation is an essential part of COPD treatment. Oxygen therapy, noninvasive nocturnal ventilation and surgical treatment options only apply to a highly selected group of patients. Disease management programmes and guideline adherence are briefly discussed. In conclusion, although there is debate as to the extent with which pharmacological therapies influence mortality, adherence to the GOLD strategy is recommended.

High volume production of nanostructured materials

DOEpatents

Ripley, Edward B [Knoxville, TN; Morrell, Jonathan S [Knoxville, TN; Seals, Roland D [Oak Ridge, TN; Ludtka, Gerard M [Oak Ridge, TN

2009-10-13

A system and method for high volume production of nanoparticles, nanotubes, and items incorporating nanoparticles and nanotubes. Microwave, radio frequency, or infrared energy vaporizes a metal catalyst which, as it condenses, is contacted by carbon or other elements such as silicon, germanium, or boron to form agglomerates. The agglomerates may be annealed to accelerate the production of nanotubes. Magnetic or electric fields may be used to align the nanotubes during their production. The nanotubes may be separated from the production byproducts in aligned or non-aligned configurations. The agglomerates may be formed directly into tools, optionally in compositions that incorporate other materials such as abrasives, binders, carbon-carbon composites, and cermets.

Methods for high volume production of nanostructured materials

DOEpatents

Ripley, Edward B [Knoxville, TN; Morrell, Jonathan S [Knoxville, TN; Seals, Roland D [Oak Ridge, TN; Ludtka, Gerald M [Oak Ridge, TN

2011-03-22

A system and method for high volume production of nanoparticles, nanotubes, and items incorporating nanoparticles and nanotubes. Microwave, radio frequency, or infrared energy vaporizes a metal catalyst which, as it condenses, is contacted by carbon or other elements such as silicon, germanium, or boron to form agglomerates. The agglomerates may be annealed to accelerate the production of nanotubes. Magnetic or electric fields may be used to align the nanotubes during their production. The nanotubes may be separated from the production byproducts in aligned or non-aligned configurations. The agglomerates may be formed directly into tools, optionally in compositions that incorporate other materials such as abrasives, binders, carbon-carbon composites, and cermets.

Measuring impedance in congestive heart failure: Current options and clinical applications

PubMed Central

Tang, W. H. Wilson; Tong, Wilson

2011-01-01

Measurement of impedance is becoming increasingly available in the clinical setting as a tool for assessing hemodynamics and volume status in patients with heart failure. The 2 major categories of impedance assessment are the band electrode method and the implanted device lead method. The exact sources of the impedance signal are complex and can be influenced by physiologic effects such as blood volume, fluid, and positioning. This article provides a critical review of our current understanding and promises of impedance measurements, the techniques that have evolved, as well as the evidence and limitations regarding their clinical applications in the setting of heart failure management. PMID:19249408

Pressurized fluidized bed reactor

DOEpatents

Isaksson, J.

1996-03-19

A pressurized fluid bed reactor power plant includes a fluidized bed reactor contained within a pressure vessel with a pressurized gas volume between the reactor and the vessel. A first conduit supplies primary gas from the gas volume to the reactor, passing outside the pressure vessel and then returning through the pressure vessel to the reactor, and pressurized gas is supplied from a compressor through a second conduit to the gas volume. A third conduit, comprising a hot gas discharge, carries gases from the reactor, through a filter, and ultimately to a turbine. During normal operation of the plant, pressurized gas is withdrawn from the gas volume through the first conduit and introduced into the reactor at a substantially continuously controlled rate as the primary gas to the reactor. In response to an operational disturbance of the plant, the flow of gas in the first, second, and third conduits is terminated, and thereafter the pressure in the gas volume and in the reactor is substantially simultaneously reduced by opening pressure relief valves in the first and third conduits, and optionally by passing air directly from the second conduit to the turbine. 1 fig.

Pressurized fluidized bed reactor

DOEpatents

Isaksson, Juhani

1996-01-01

A pressurized fluid bed reactor power plant includes a fluidized bed reactor contained within a pressure vessel with a pressurized gas volume between the reactor and the vessel. A first conduit supplies primary gas from the gas volume to the reactor, passing outside the pressure vessel and then returning through the pressure vessel to the reactor, and pressurized gas is supplied from a compressor through a second conduit to the gas volume. A third conduit, comprising a hot gas discharge, carries gases from the reactor, through a filter, and ultimately to a turbine. During normal operation of the plant, pressurized gas is withdrawn from the gas volume through the first conduit and introduced into the reactor at a substantially continuously controlled rate as the primary gas to the reactor. In response to an operational disturbance of the plant, the flow of gas in the first, second, and third conduits is terminated, and thereafter the pressure in the gas volume and in the reactor is substantially simultaneously reduced by opening pressure relief valves in the first and third conduits, and optionally by passing air directly from the second conduit to the turbine.

Grey water characteristics and treatment options for rural areas in Jordan.

PubMed

Halalsheh, M; Dalahmeh, S; Sayed, M; Suleiman, W; Shareef, M; Mansour, M; Safi, M

2008-09-01

Low water consumption in rural areas in Jordan had resulted in the production of concentrated grey water. Average COD, BOD and TSS values were 2568mg/l, 1056mg/l and 845mg/l, respectively. The average grey water generation was measured to be 14L/c.d. Three different treatment options were selected based on certain criterions, and discussed in this article. The examined treatment systems are septic tank followed by intermittent sand filter; septic tank followed by wetlands; and UASB-hybrid reactor. Advantages and disadvantages of each system are presented. It was concluded that UASB-hybrid reactor would be the most suitable treatment option in terms of compactness and simplicity in operation. The volume of UASB-hybrid reactor was calculated to be 0.268m(3) with a surface area of 0.138m(2) for each house having 10 inhabitants on average. Produced effluent is expected to meet Jordanian standards set for reclaimed water reuse in irrigating fruit trees.

Solid rocket booster performance evaluation model. Volume 1: Engineering description

NASA Technical Reports Server (NTRS)

1974-01-01

The space shuttle solid rocket booster performance evaluation model (SRB-II) is made up of analytical and functional simulation techniques linked together so that a single pass through the model will predict the performance of the propulsion elements of a space shuttle solid rocket booster. The available options allow the user to predict static test performance, predict nominal and off nominal flight performance, and reconstruct actual flight and static test performance. Options selected by the user are dependent on the data available. These can include data derived from theoretical analysis, small scale motor test data, large motor test data and motor configuration data. The user has several options for output format that include print, cards, tape and plots. Output includes all major performance parameters (Isp, thrust, flowrate, mass accounting and operating pressures) as a function of time as well as calculated single point performance data. The engineering description of SRB-II discusses the engineering and programming fundamentals used, the function of each module, and the limitations of each module.

The development of an MRI lesion quantifying system for multiple sclerosis patients undergoing treatment

NASA Astrophysics Data System (ADS)

Moin, Paymann; Ma, Kevin; Amezcua, Lilyana; Gertych, Arkadiusz; Liu, Brent

2009-02-01

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that affects approximately 2.5 million people worldwide. Magnetic resonance imaging (MRI) is an established tool for the assessment of disease activity, progression and response to treatment. The progression of the disease is variable and requires routine follow-up imaging studies. Currently, MRI quantification of multiple sclerosis requires a manual approach to lesion measurement and yields an estimate of lesion volume and interval change. In the setting of several prior studies and a long treatment history, trends related to treatment change quickly become difficult to extrapolate. Our efforts seek to develop an imaging informatics based MS lesion computer aided detection (CAD) package to quantify and track MS lesions including lesion load, volume, and location. Together, with select clinical parameters, this data will be incorporated into an MS specific e- Folder to provide decision support to evaluate and assess treatment options for MS in a manner tailored specifically to an individual based on trends in MS presentation and progression.

Medical Grade Water Generation for Intravenous Fluid Production on Exploration Missions

NASA Technical Reports Server (NTRS)

Niederhaus, Charles E.; Barlow, Karen L.; Griffin, DeVon W.; Miller, Fletcher J.

2008-01-01

This document describes the intravenous (IV) fluids requirements for medical care during NASA s future Exploration class missions. It further discusses potential methods for generating such fluids and the challenges associated with different fluid generation technologies. The current Exploration baseline mission profiles are introduced, potential medical conditions described and evaluated for fluidic needs, and operational issues assessed. Conclusions on the fluid volume requirements are presented, and the feasibility of various fluid generation options are discussed. A separate report will document a more complete trade study on the options to provide the required fluids.At the time this document was developed, NASA had not yet determined requirements for medical care during Exploration missions. As a result, this study was based on the current requirements for care onboard the International Space Station (ISS). While we expect that medical requirements will be different for Exploration missions, this document will provide a useful baseline for not only developing hardware to generate medical water for injection (WFI), but as a foundation for meeting future requirements. As a final note, we expect WFI requirements for Exploration will be higher than for ISS care, and system capacity may well need to be higher than currently specified.

Fostering Children's Social Competence: The Teacher's Role. Volume 8 of the NAEYC Research into Practice Series.

ERIC Educational Resources Information Center

Katz, Lilian G.; McClellan, Diane E.

This book presents options for early childhood educators to consider as they make decisions concerning how best to foster the development of children's social competence. The book maintains that social competence is most likely to be acquired and strengthened in an atmosphere of warmest acceptance, respect, and deep faith in the child's capacity…

Data summary of municipal solid waste management alternatives. Volume 4, Appendix B: RDF technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1992-10-01

This appendix contains background information, technical descriptions, economic data, mass and energy balances, and information on environmental releases for the refuse derived fuels (RDF) option in municipal solid waste management alternatives. Demonstration programs at St. Louis, Missouri; Franklin, Ohio; and Delaware are discussed. Information on pellet production and cofiring with coal is also presented.

Investigating the use of small-diameter softwood as guardrail posts: static test results

Treesearch

David E. Kretschmann; Ron Faller; Jason Hascall; John Reid; Dean Sicking; John Rohde; Dick Shilts; Tim Nelson

2007-01-01

Round guardrail posts may provide an important value added option for small-diameter thinnings. Such posts require minimum processing and have been shown to have higher strength compared to the equivalent rectangular volume. The resulting value-added product may bring a higher return compared to lumber. The obstacles to immediate utilization of ponderosa pine and...

Community biomass handbook. Volume I: thermal wood energy

Treesearch

D. Becker; E. Lowell; D. Bihn; R. Anderson; S. Taff

2014-01-01

This handbook and financial app is a guide to help communities quickly determine if biomass energy projects might work for them so that this option is not overlooked. Its purpose is as a screening tool designed to save significant time, resources, and investment by weeding out those wood energy projects that may never come to fruition from those that have a chance of...

Proceedings of the Third Annual Student Symposium on Marine Affairs (University of Hawaii, Manoa Campus, January 13, 1978).

ERIC Educational Resources Information Center

1978

This volume of the proceedings of the Third Annual Student Symposium on Marine Affairs contains 32 papers in eight categories: (1) coastal zone management; (2) marine resources; (3) aquaculture; (4) alternative marine energy sources; (5) ocean engineering; (6) recreational facilities; (7) marine biology; and (8) options. The papers are the…

76 FR 20793 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

..., approximately 40% of CBOE Floor Broker Trading Permit Holders would fall under Tier 1 and would no longer be... Holders fall under Tier 4, having a PAR Official execute more than 75% of the Trading Permit Holder's... ``Exchange'') proposes to amend its Fees Schedule to establish volume threshold tiers for the assessment of...

Digital adaptive controllers for VTOL vehicles. Volume 2: Software documentation

NASA Technical Reports Server (NTRS)

Hartmann, G. L.; Stein, G.; Pratt, S. G.

1979-01-01

The VTOL approach and landing test (VALT) adaptive software is documented. Two self-adaptive algorithms, one based on an implicit model reference design and the other on an explicit parameter estimation technique were evaluated. The organization of the software, user options, and a nominal set of input data are presented along with a flow chart and program listing of each algorithm.

Alternative to Blood Replacement in the Critically Ill.

PubMed

Tolich, Deborah J; McCoy, Kelly

2017-09-01

This article reviews treatments and strategies that can be used to reduce, or as adjuncts to, blood transfusion to manage blood volumes in patients who are critically ill. Areas addressed include iatrogenic anemia, fluid management, pharmaceutical agents, hemostatic agents, hemoglobin-based oxygen carriers, and management of patients for whom blood is not an option. Copyright © 2017 Elsevier Inc. All rights reserved.

A cost engineered launch vehicle for space tourism

NASA Astrophysics Data System (ADS)

Koelle, -Ing. Dietrich E., , Dr.

1999-09-01

The paper starts with a set of major requirements for a space tourism vehicle and discusses major vehicle options proposed for this purpose. It seems that the requirements can be met best with a Ballistic SSTO Vehicle which has the additional advantage of lowest development cost compared to other launch vehicle options — important for a commercial development venture. The BETA Ballistic Reusable Vehicle Concept is characterized by the plug nozzle cluster engine configuration where the plug nozzle serves also as base plate and re-entry heat shield. In this case no athmospheric turn maneuver is required (as in case-of the front-entry Delta-Clipper DC-Y concept). In our specific case for space tourism this mode has the avantage that the forces at launch and reentry are in exactly the same direction, easing passenger seating arrangements. The second basic advantage is the large available volume on top of the vehicle providing ample space for passenger accomodation, visibility and volume for zero-g experience (free floating), one of the major passenger mission requirements. An adequate passenger cabin design for 100 passengers is presented, as well as the modern BETA-STV Concept with its mass allocations.

Lower Extremity Free Flaps for Breast Reconstruction.

PubMed

Dayan, Joseph H; Allen, Robert J

2017-11-01

Thigh-based flaps are typically a secondary option for breast reconstruction because of concerns regarding limited tissue volume and donor-site morbidity. In recent years, there have been a number of new techniques and insights that have resulted in greater flexibility and improved outcomes. This article reviews lessons learned from a large collective experience using the following 4 flaps: transverse upper gracilis also known as transverse myocutaneous gracilis, diagonal upper gracilis, profunda artery perforator, and lateral thigh perforator flaps. Flap selection considerations include the patient's fat distribution and skin laxity, perforator anatomy, and scar location. Pearls to minimize donor-site morbidity include avoiding major lymphatic collectors in the femoral triangle and along the greater saphenous vein and respecting the limits of flap dimension to reduce wound healing complications and distal ischemia. Limited flap volume may be addressed with stacking another flap from the contralateral thigh or primary fat grafting as opposed to overaggressive flap harvest from a single thigh. A detailed review of the benefits and disadvantages of each flap and strategies to improve results is discussed. With careful planning and selection, thigh-based flaps can provide a reliable option patients desiring autologous breast reconstruction.

Mass and Elite Views on Nuclear Security: US National Security Surveys 1993-1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

HERRON,KERRY G.; JENKINS-SMITH,HANK C.; HUGHES,SCOTT D.

This is the fourth report in an ongoing series of studies examining how US perspectives about nuclear security are evolving in the post-Cold War era. In Volume 1 the authors present findings from a nationwide telephone survey of randomly selected members of the US general public conducted from 13 September to 14 October 1999. Results are compared to findings from previous surveys in this series conducted in 1993, 1995, and 1997, and trends are analyzed. Key areas of investigation reported in Volume 1 include evolving perceptions of nuclear weapons risks and benefits, preferences for related policy and spending issues, andmore » views about three emerging issue areas: deterrent utility of precision guided munitions; response options to attacks in which mass casualty weapons are used; and expectations about national missile defenses. In this volume they relate respondent beliefs about nuclear security to perceptions of nuclear risks and benefits and to policy preferences. They develop causal models to partially explain key preferences, and they employ cluster analysis to group respondents into four policy relevant clusters characterized by similar views and preferences about nuclear security within each cluster. Systematic links are found among respondent demographic characteristics, perceptions of nuclear risks and benefits, policy beliefs, and security policy and spending preferences. In Volume 2 they provide analysis of in-depth interviews with fifty members of the US security policy community.« less

Current Status of Prostate Artery Embolization for Lower Urinary Tract Symptoms: Review of World Literature.

PubMed

Jones, Patrick; Rai, Bhavan Prasad; Nair, Rajesh; Somani, Bhaskar K

2015-10-01

Prostate artery embolization has emerged as a promising treatment for lower urinary tract symptoms secondary to benign prostatic hyperplasia. However, although it has gained increasing attention in radiology literature, it remains under-reported from a urologic perspective. We aim at providing an up-to-date review of this minimally invasive technique. Evidence suggests it is a promising and effective option for patients with large prostate volumes, multiple comorbidities, and suboptimal results from pharmacotherapy. Larger, randomized studies with longer follow-up periods are needed for this technique to be formally established in the urology community. Copyright © 2015 Elsevier Inc. All rights reserved.

Space Station needs, attributes and architectural options. Volume 2, book 1, part 2, task 1: Mission requirements

NASA Technical Reports Server (NTRS)

1983-01-01

Mission areas analyzed for input to the baseline mission model include: (1) commercial materials processing, including representative missions for producing metallurgical, chemical and biological products; (2) commercial Earth observation, represented by a typical carry-on mission amenable to commercialization; (3) solar terrestrial and resource observations including missions in geoscience and scientific land observation; (4) global environment, including representative missions in meteorology, climatology, ocean science, and atmospheric science; (5) materials science, including missions for measuring material properties, studying chemical reactions and utilizing the high vacuum-pumping capacity of space; and (6) life sciences with experiments in biomedicine and animal and plant biology.

Power generation technology options for a Mars mission

NASA Technical Reports Server (NTRS)

Bozek, John M.; Cataldo, Robert L.

1994-01-01

The power requirements and resultant power system performances of an aggressive Mars mission are characterized. The power system technologies discussed will support both cargo and piloted space transport vehicles as well as a six-person crew on the Martian surface for 600 days. The mission uses materials transported by cargo vehicles and materials produced using in-situ planetary feed stock to establish a life-support cache and infrastructure for the follow-on piloted lander. Numerous power system technical options are sized to meet the mission power requirements using conventional and solar, nuclear, and wireless power transmission technologies for stationary, mobile surface, and space applications. Technology selections will depend on key criteria such as mass, volume, area, maturity, and application flexibility.

Steam engine research for solar parabolic dish

NASA Technical Reports Server (NTRS)

Demler, R. L.

1981-01-01

The parabolic dish solar concentrator provides an opportunity to generate high grade energy in a modular system. Most of the capital is projected to be in the dish and its installation. Assurance of a high production demand of a standard dish could lead to dramatic cost reductions. High production volume in turn depends upon maximum application flexibility by providing energy output options, e.g., heat, electricity, chemicals and combinations thereof. Subsets of these options include energy storage and combustion assist. A steam engine design and experimental program is described which investigate the efficiency potential of a small 25 kW compound reheat cycle piston engine. An engine efficiency of 35 percent is estimated for a 700 C steam temperature from the solar receiver.

Spectrum Orbit Utilization Program documentation: SOUP5 version 3.8 user's manual, volume 1, chapters 1 through 5

NASA Technical Reports Server (NTRS)

Davidson, J.; Ottey, H. R.; Sawitz, P.; Zusman, F. S.

1985-01-01

The underlying engineering and mathematical models as well as the computational methods used by the Spectrum Orbit Utilization Program 5 (SOUP5) analysis programs are described. Included are the algorithms used to calculate the technical parameters, and references to the technical literature. The organization, capabilities, processing sequences, and processing and data options of the SOUP5 system are described. The details of the geometric calculations are given. Also discussed are the various antenna gain algorithms; rain attenuation and depolarization calculations; calculations of transmitter power and received power flux density; channelization options, interference categories, and protection ratio calculation; generation of aggregrate interference and margins; equivalent gain calculations; and how to enter a protection ratio template.

Entropy Production in Chemical Reactors

NASA Astrophysics Data System (ADS)

Kingston, Diego; Razzitte, Adrián C.

2017-06-01

We have analyzed entropy production in chemically reacting systems and extended previous results to the two limiting cases of ideal reactors, namely continuous stirred tank reactor (CSTR) and plug flow reactor (PFR). We have found upper and lower bounds for the entropy production in isothermal systems and given expressions for non-isothermal operation and analyzed the influence of pressure and temperature in entropy generation minimization in reactors with a fixed volume and production. We also give a graphical picture of entropy production in chemical reactions subject to constant volume, which allows us to easily assess different options. We show that by dividing a reactor into two smaller ones, operating at different temperatures, the entropy production is lowered, going as near as 48 % less in the case of a CSTR and PFR in series, and reaching 58 % with two CSTR. Finally, we study the optimal pressure and temperature for a single isothermal PFR, taking into account the irreversibility introduced by a compressor and a heat exchanger, decreasing the entropy generation by as much as 30 %.

A Tabletop Persistent-Mode, Liquid-Helium-Free, 1.5-T/90-mm MgB2 “Finger” MRI Magnet for Osteoporosis Screening: Two Design Options

PubMed Central

Park, Dongkeun; Bascuñán, Juan; Michael, Philip C.; Iwasa, Yukikazu

2017-01-01

In this paper we present two design options for a tabletop liquid-helium-free, persistent-mode 1.5-T/90-mm MgB2 “finger” MRI magnet for osteoporosis screening. Both designs, one with and the other without an iron yoke, satisfy the following criteria: 1) 1.5-T center field with a 90-mm room-temperature bore for a finger to be placed at the magnet center; 2) spatial field homogeneity of <5 ppm over a 20-mm diameter of spherical volume (DSV); 3) persistent-mode operation with temporal stability of <0.1 ppm/hr; 4) liquid-helium-free operation; 5) 5-gauss fringe field radius of <50 cm from the magnet center; and 6) small and light enough for placement on an exam table. Although the magnet is designed to operate nominally at 10 K, maintained by a cryocooler, it has a 5-K temperature margin to keep its 1.5-T persistent field up to 15 K. The magnet will be immersed in a volume of solid nitrogen (SN2) that provides additional thermal mass when the cryocooler is switched off to provide a vibration-free measurement environment. The SN2 enables the magnet to maintain its persistent field over a period of time sufficient for quiescent measurement, while still limiting the magnet operating temperature to ≤15 K. We discuss first pros and cons of each design, and then further studies of our proposed MgB2 finger MRI magnet. PMID:29456437

State of the art and review on the treatment technologies of water reverse osmosis concentrates.

PubMed

Pérez-González, A; Urtiaga, A M; Ibáñez, R; Ortiz, I

2012-02-01

The growing demand for fresh water is partially satisfied by desalination plants that increasingly use membrane technologies and among them reverse osmosis to produce purified water. Operating with water recoveries from 35% to 85% RO plants generate huge volumes of concentrates containing all the retained compounds that are commonly discharged to water bodies and constitute a potentially serious threat to marine ecosystems; therefore there is an urgent need for environmentally friendly management options of RO brines. This paper gives an overview on the potential treatments to overcome the environmental problems associated to the direct discharge of RO concentrates. The treatment options have been classified according to the source of RO concentrates and the maturity of the technologies. For the sake of clarity three different sources of RO concentrates are differentiated i) desalination plants, ii) tertiary processes in WWTP, and iii) mining industries. Starting with traditional treatments such as evaporation and crystallization other technologies that have emerged in last years to reduce the volume of the concentrate before disposal and with the objective of achieving zero liquid discharge and recovery of valuable compounds from these effluents are also reviewed. Most of these emerging technologies have been developed at laboratory or pilot plant scale (see Table 1). With regard to RO concentrates from WWTP, the manuscript addresses recent studies that are mainly focused on reducing the organic pollutant load through the application of innovative advanced oxidation technologies. Finally, works that report the treatment of RO concentrates from industrial sources are analyzed as well. Copyright © 2011 Elsevier Ltd. All rights reserved.

The role of volume of multi-surface restorations in posterior teeth: Treatment options.

PubMed

Janus, Charles; Sbeih, Izzat; Best, Al M

2011-01-01

Teeth containing large defective restorations are frequently indicated to receive crowns to prevent catastrophic fracture. There is a considerable lack of consensus as to when the size of an existing restoration needing retreatment is sufficiently large to warrant a crown. In addition, the treating dentist's gender, age, and location also have been found to influence this decision. An in vitro method was developed to estimate a restoration's volume proportion (VP). This study validates and investigates correlations between the restoration's VP, the decision to indicate a crown, and the responding dentist's demographic information. The coronal portions of occlusal view and bitewing radiographic images of restored posterior teeth were traced to yield four surface areas used in estimating the restoration's VP. An online survey of 15 patients, including intraoral and radiographic images of defective restorations, was created. Dentists were invited to select treatment for each patient's tooth, with options including replacing the restoration only or indicating a crown. Analysis was accomplished using repeated-measures logistic regression. Of the 300 respondents, 17% were female and 14% were from outside the U.S. The relationship between a responding dentist indicating a crown and the restoration's VP, the tooth type (molar or premolar), and nationality (U.S. or foreign dentist) were all deemed statistically significant. Crowns were indicated for molars significantly more often than for premolars, with a significant VP interaction. The final model of tooth, VP, nationality, and the interaction of tooth and VP was used to generate mean predicted proportions for indicating a crown.

A Tabletop Persistent-Mode, Liquid-Helium-Free, 1.5-T/90-mm MgB2 "Finger" MRI Magnet for Osteoporosis Screening: Two Design Options.

PubMed

Park, Dongkeun; Bascuñán, Juan; Michael, Philip C; Iwasa, Yukikazu

2018-04-01

In this paper we present two design options for a tabletop liquid-helium-free, persistent-mode 1.5-T/90-mm MgB 2 "finger" MRI magnet for osteoporosis screening. Both designs, one with and the other without an iron yoke, satisfy the following criteria: 1) 1.5-T center field with a 90-mm room-temperature bore for a finger to be placed at the magnet center; 2) spatial field homogeneity of <5 ppm over a 20-mm diameter of spherical volume (DSV); 3) persistent-mode operation with temporal stability of <0.1 ppm/hr; 4) liquid-helium-free operation; 5) 5-gauss fringe field radius of <50 cm from the magnet center; and 6) small and light enough for placement on an exam table. Although the magnet is designed to operate nominally at 10 K, maintained by a cryocooler, it has a 5-K temperature margin to keep its 1.5-T persistent field up to 15 K. The magnet will be immersed in a volume of solid nitrogen (SN 2 ) that provides additional thermal mass when the cryocooler is switched off to provide a vibration-free measurement environment. The SN 2 enables the magnet to maintain its persistent field over a period of time sufficient for quiescent measurement, while still limiting the magnet operating temperature to ≤15 K. We discuss first pros and cons of each design, and then further studies of our proposed MgB 2 finger MRI magnet.

Hydrologic analysis of the challenges facing water resources and sustainable development of Wadi Feiran basin, southern Sinai, Egypt

NASA Astrophysics Data System (ADS)

Ahmed, Ayman A.; Diab, Maghawri S.

2018-04-01

Wadi Feiran basin is one of the most promising areas in southern Sinai (Egypt) for establishing new communities and for growth in agriculture, tourism, and industry. The present challenges against development include water runoff hazards (flash flooding), the increasing water demand, and water scarcity and contamination. These challenges could be mitigated by efficient use of runoff and rainwater through appropriate management, thereby promoting sustainable development. Strategies include the mitigation of runoff hazards and promoting the natural and artificial recharge of aquifers. This study uses a watershed modeling system, geographic information system, and classification scheme to predict the effects of various mitigation options on the basin's water resources. Rainwater-harvesting techniques could save more than 77% of the basin's runoff (by volume), which could be used for storage and aquifer recharge. A guide map is provided that shows possible locations for the proposed mitigation options in the study basin. Appropriate measures should be undertaken urgently: mitigation of groundwater contamination (including effective sewage effluent management); regular monitoring of the municipal, industrial and agricultural processes that release contaminants; rationalization and regulation of the application of agro-chemicals to farmland; and regular monitoring of contaminants in groundwater. Stringent regulations should be implemented to prevent wastewater disposal to the aquifers in the study area.

Mandibular Reconstruction with Lateral Tibial Bone Graft: An Excellent Option for Oral and Maxillofacial Surgery.

PubMed

Miceli, Ana Lucia Carpi; Pereira, Livia Costa; Torres, Thiago da Silva; Calasans-Maia, Mônica Diuana; Louro, Rafael Seabra

2017-12-01

Autogenous bone grafts are the gold standard for reconstruction of atrophic jaws, pseudoarthroses, alveolar clefts, orthognathic surgery, mandibular discontinuity, and augmentation of sinus maxillary. Bone graft can be harvested from iliac bone, calvarium, tibial bone, rib, and intraoral bone. Proximal tibia is a common donor site with few reported problems compared with other sites. The aim of this study was to evaluate the use of proximal tibia as a donor area for maxillofacial reconstructions, focusing on quantifying the volume of cancellous graft harvested by a lateral approach and to assess the complications of this technique. In a retrospective study, we collected data from 31 patients, 18 women and 13 men (mean age: 36 years, range: 19-64), who were referred to the Department of Oral and Maxillofacial Surgery at the Servidores do Estado Federal Hospital. Patients were treated for sequelae of orthognathic surgery, jaw fracture, nonunion, malunion, pathology, and augmentation of bone volume to oral implant. The technique of choice was lateral access of proximal tibia metaphysis for graft removal from Gerdy tubercle under general anesthesia. The mean volume of bone harvested was 13.0 ± 3.7 mL (ranged: 8-23 mL). Only five patients (16%) had minor complications, which included superficial infection, pain, suture dehiscence, and unwanted scar. However, none of these complications decreases the result and resolved completely. We conclude that proximal tibia metaphysis for harvesting cancellous bone graft provides sufficient volume for procedures in oral and maxillofacial surgery with minimal postoperative morbidity.

A practical approach to evidence-based dentistry: VI: How to use a systematic review.

PubMed

Carrasco-Labra, Alonso; Brignardello-Petersen, Romina; Glick, Michael; Guyatt, Gordon H; Azarpazhooh, Amir

2015-04-01

Dental practitioners face new clinical challenges on a daily basis. New treatment options and diagnostic tools are disseminated quickly, and the volume of articles and new evidence is overwhelming. Systematic reviews summarize and synthesize the available evidence related to diagnosis, therapy, prognosis, and harm for clinicians, patients, and decision makers. Such reviews represent one of the most powerful tools to translate knowledge into action. The critical appraisal of this type of study involves assessing the risk of bias, results, and applicability of such study. The authors provide guidance for clinicians to critically appraise systematic reviews and apply the findings in clinical practice. Copyright © 2015 American Dental Association. Published by Elsevier Inc. All rights reserved.

Effectiveness of Riluzole as a pharmacotherapeutic treatment option for early cervical myelopathy: a double-blinded, placebo-controlled randomised controlled trial.

PubMed

Rajasekaran, S; Aiyer, Siddharth N; Shetty, Ajoy Prasad; Kanna, Rishi Mugesh; Maheswaran, Anupama; Shetty, Janardhan Yerram

2016-06-01

To evaluate the effectiveness of Riluzole as a pharmacotherapeutic treatment option for early cervical myelopathy using clinical parameters and DTI analysis. Early cervical myelopathy cases with MJOA scores ≥13, were recruited for the double-blinded, placebo-controlled randomised control trial. Thirty cases with fifteen cases each in the test and placebo group were studied. Analysis was done using diffusion tensor imaging (DTI) and clinical evaluation, pre- and post-institution of sodium channel blocker Riluzole for a period of 1 month (50 mg twice daily). Placebo group was treated with Vitamin B complex tablets. Diffusion co-efficient fractional anisotrophy (FA), apparent diffusion co-efficient (ADC), volume ratio (VR), relative anisotrophy (RA) and Eigen vectors were calculated. Outcomes analysis was based on clinical scores of MJOA, Nurick grading, SF-12, NDI, and statistical analysis of DTI datametrics. The mean MJOA score was 15.6 (13-17) with no significant change in the test and control groups. The mean ADC, FA values were 1533.36 (1238-1779) and 494.36 (364-628) and changed to 1531.57 (1312-2091) and 484.86 (294-597), respectively, in the Riluzole group. However, the changes in the values of ADC, FA, and other co-efficients including VR, RA and eigenvectors in the two groups were not statistically significant. The functional scores in the SF-12 and NDI questionnaires did not change significantly. Our study did not show a significant change in the clinical outcome and DTI Indices with the use of Riluzole as a standalone pharmacotherapeutic agent for early cervical myelopathy. More studies may be needed to confirm the usefulness of Riluzole as a treatment option for cervical myelopathy.

Hyaluronic acid in the treatment of knee osteoarthritis: a systematic review and meta-analysis with emphasis on the efficacy of different products.

PubMed

Colen, Sascha; van den Bekerom, Michel P J; Mulier, Michiel; Haverkamp, Daniël

2012-08-01

Although accepted as a conservative treatment option for knee osteoarthritis, the debate about the effectiveness of intra-articular treatment with hyaluronic acid (HA) is still ongoing because of contrasting outcomes in different clinical studies. Several well designed clinical studies showed a significant improvement in pain at follow-up compared with baseline but no significant improvement comparing the efficacy of HA with placebo (saline) or with other conservative treatment options. Notwithstanding the effectiveness of different types of intra-articular HA products, the question of whether one HA product is better than another is still unanswered. In this systematic review we compare the effects of intra-articularly administered HA with intra-articularly administered placebo in general and, more specifically, the effects of individual HA products with placebo. We also compare the efficacy of different HA products. A systematic review of randomized controlled trials (RCTs) was conducted using databases including MEDLINE, Cochrane Database of Systematic Reviews, Cochrane Clinical Trial Register and EMBASE. Seventy-four RCTs were included in this systematic review. HA improves pain by approximately 40-50% compared with baseline levels. However, when compared with saline the difference in efficacy is not that large. Due to a large 'placebo effect' of saline (approximately 30% pain reduction, persisting for at least 3 months) we determined a weighted mean difference between the efficacy of HA and saline of just 10.20 using the visual analog scale for pain. It is debatable whether this difference reaches the minimum clinically important difference. Comparing the different HA products, which vary in the molecular weight, concentration, and volume of HA, we were not able to conclude that one brand has a better efficacy than another due to the heterogeneity of the studies and outcomes. In the future it will be important to determine the exact mechanism of action of placebo as this may give us an idea of how to treat osteoarthritis more efficiently. Due to the limitations of this review (follow-up of just 3 months and large heterogeneity of the included studies), it is also important to compare the different HA products to determine which product(s), or which molecular weight range, concentration, or volume of HA is the best option to treat osteoarthritis. Our recommendation is to start large (multicenter) RCTs to give us more evidence about the efficacy of the different HA products.

Variation in rates of breast cancer surgery: A national analysis based on French Hospital Episode Statistics.

PubMed

Rococo, E; Mazouni, C; Or, Z; Mobillion, V; Koon Sun Pat, M; Bonastre, J

2016-01-01

Minimum volume thresholds were introduced in France in 2008 to improve the quality of cancer care. We investigated whether/how the quality of treatment decisions in breast cancer surgery had evolved before and after this policy was implemented. We used Hospital Episode Statistics for all women having undergone breast conserving surgery (BCS) or mastectomy in France in 2005 and 2012. Three surgical procedures considered as better treatment options were analyzed: BCS, immediate breast reconstruction (IBR) and sentinel lymph node biopsy (SLNB). We studied the mean rates and variation according to the hospital profile and volume. Between 2005 and 2012, the volume of breast cancer surgery increased by 11% whereas one third of the hospitals no longer performed this type of surgery. In 2012, the mean rate of BCS was 74% and similar in all hospitals whatever the volume. Conversely, IBR and SLNB rates were much higher in cancer centers (CC) and regional teaching hospitals (RTH) [IBR: 19% and 14% versus 8% on average; SLNB: 61% and 47% versus 39% on average]; the greater the hospital volume, the higher the IBR and SLNB rates (p < 0.0001). Overall, whatever the surgical procedure considered, inter-hospital variation in rates declined substantially in CC and RTH. We identified considerable variation in IBR and SLNB rates between French hospitals. Although more complex and less standardized than BCS, most clinical guidelines recommended these procedures. This apparent heterogeneity suggests unequal access to high-quality procedures for women with breast cancer. Copyright © 2015 Elsevier Ltd. All rights reserved.

Wastewater Conveyance Feasibility Investigation, Cranston, RI, Volume 1 Main Report and Environmental Assessment

DTIC Science & Technology

1995-05-01

K Task 10c - Water Quality and Hydrology Assessment APPENDIX L Task 10d - Archaeological/Historic Assessment APPENDIX M Task l~e - Ecological ...options to select a proposed project. The first phase included feasibility level design, cost estimating, water quality, ecological , archaeological and...Assessment 47 Ecological Assessment 49 Historic/Archaeological Assessment 53 Socio/Economic Assessment 54 Proposed Project 57 Chapter 7. PRELIMINARY

Fuel gas conditioning process

DOEpatents

Lokhandwala, Kaaeid A.

2000-01-01

A process for conditioning natural gas containing C.sub.3+ hydrocarbons and/or acid gas, so that it can be used as combustion fuel to run gas-powered equipment, including compressors, in the gas field or the gas processing plant. Compared with prior art processes, the invention creates lesser quantities of low-pressure gas per unit volume of fuel gas produced. Optionally, the process can also produce an NGL product.

NASTRAN thermal analyzer: Theory and application including a guide to modeling engineering problems, volume 2. [sample problem library guide

NASA Technical Reports Server (NTRS)

Jackson, C. E., Jr.

1977-01-01

A sample problem library containing 20 problems covering most facets of Nastran Thermal Analyzer modeling is presented. Areas discussed include radiative interchange, arbitrary nonlinear loads, transient temperature and steady-state structural plots, temperature-dependent conductivities, simulated multi-layer insulation, and constraint techniques. The use of the major control options and important DMAP alters is demonstrated.

Cost/benefit tradeoffs for reducing the energy consumption of the commercial air transportation system. Volume 2: Market and economic analyses

NASA Technical Reports Server (NTRS)

Vanabkoude, J. C.

1976-01-01

The impact of the most promising fuel conserving options on fuel consumption, passenger demand, operating costs, and airline profits when implemented into the U.S. domestic and international airline fleets is assessed. The potential fuel savings achievable in the U.S. scheduled air transportation system over the forecast period, 1973-1990, are estimated.

MINIVER upgrade for the AVID system. Volume 2: LANMIN input guide

NASA Technical Reports Server (NTRS)

Engel, C. D.; Schmitz, C. P.

1983-01-01

In order to effectively incorporate MINIVER into the AVID system, several changes to MINIVER were made. The thermal conduction options in MINIVER were removed and a new Explicit Interactive Thermal Structures (EXITS) code was developed. Many upgrades to the MINIVER code were made and a new Langley version of MINIVER called LANMIN was created. A user input guide for LANMIN is provided.

Space Station needs, attributes and architectural options. Volume 2, book 1, part 1: Mission requirements

NASA Technical Reports Server (NTRS)

1983-01-01

The baseline mission model used to develop the space station mission-related requirements is described as well as the 90 civil missions that were evaluated, (including the 62 missions that formed the baseline model). Mission-related requirements for the space station baseline are defined and related to space station architectural development. Mission-related sensitivity analyses are discussed.

Effectiveness of low-dose pasireotide in a patient with Cushing's disease: antiproliferative effect and predictivity of a short pasireotide suppression test.

PubMed

Grossrubatscher, Erika; Zampetti, Benedetta; Dalino Ciaramella, Paolo; Doneda, Paola; Loli, Paola

2015-08-01

This case shows efficacy of low-dose pasireotide in biochemical and clinical control of severe hypercortisolism and in tumor volume reduction in a patient with an ACTH-secreting macroadenoma. The drug may be an option for long-term treatment in some patients where control of tumor mass is an important clinical endpoint.

Evaluation of a microwave based reactor for the treatment of blackwater sludge

PubMed Central

Mawioo, Peter M.; Rweyemamu, Audax; Garcia, Hector A.; Hooijmans, Christine M.; Brdjanovic, Damir

2016-01-01

A laboratory-scale microwave (MW) unit was applied to treat fresh blackwater sludge that represented fecal sludge (FS) produced at heavily used toilet facilities. The sludge was exposed to MW irradiation at different power levels and for various durations. Variables such as sludge volume and pathogen reduction were observed. The results demonstrated that the MW is a rapid and efficient technology that can reduce the sludge volume by over 70% in these experimental conditions. The concentration of bacterial pathogenic indicator E. coli also decreased to below the analytical detection levels. Furthermore, the results indicated that the MW operational conditions including radiation power and contact time can be varied to achieve the desired sludge volume and pathogen reduction. MW technology can be further explored for the potential scaling-up as an option for rapid treatment of FS from intensively used sanitation facilities such as in emergency situations. PMID:26799809

Proceedings of the American Power Conference. Volume 58-I

DOE Office of Scientific and Technical Information (OSTI.GOV)

McBride, A.E.

1996-10-01

This is volume 58-I of the proceedings of the American Power Conference, 1996, Technology for Competition and Globalization. The topics of the papers include power plant DC issues; cost of environmental compliance; advanced coal systems -- environmental performance; technology for competition in dispersed generation; superconductivity technologies for electric utility applications; power generation trends and challenges in China; aging in nuclear power plants; innovative and competitive repowering options; structural examinations, modifications and repairs; electric load forecasting; distribution planning; EMF effects; fuzzy logic and neural networks for power plant applications; electrokinetic decontamination of soils; integrated gasification combined cycle; advances in fusion; coolingmore » towers; relays; plant controls; flue gas desulfurization; waste product utilization; and improved technologies.« less

Pressurized fluidized bed reactor and a method of operating the same

DOEpatents

Isaksson, J.

1996-02-20

A pressurized fluid bed reactor power plant includes a fluidized bed reactor contained within a pressure vessel with a pressurized gas volume between the reactor and the vessel. A first conduit supplies primary gas from the gas volume to the reactor, passing outside the pressure vessel and then returning through the pressure vessel to the reactor, and pressurized gas is supplied from a compressor through a second conduit to the gas volume. A third conduit, comprising a hot gas discharge, carries gases from the reactor, through a filter, and ultimately to a turbine. During normal operation of the plant, pressurized gas is withdrawn from the gas volume through the first conduit and introduced into the reactor at a substantially continuously controlled rate as the primary gas to the reactor. In response to an operational disturbance of the plant, the flow of gas in the first, second, and third conduits is terminated, and thereafter the pressure in the gas volume and in the reactor is substantially simultaneously reduced by opening pressure relief valves in the first and third conduits, and optionally by passing air directly from the second conduit to the turbine. 1 fig.

Pressurized fluidized bed reactor and a method of operating the same

DOEpatents

Isaksson, Juhani

1996-01-01

A pressurized fluid bed reactor power plant includes a fluidized bed reactor contained within a pressure vessel with a pressurized gas volume between the reactor and the vessel. A first conduit supplies primary gas from the gas volume to the reactor, passing outside the pressure vessel and then returning through the pressure vessel to the reactor, and pressurized gas is supplied from a compressor through a second conduit to the gas volume. A third conduit, comprising a hot gas discharge, carries gases from the reactor, through a filter, and ultimately to a turbine. During normal operation of the plant, pressurized gas is withdrawn from the gas volume through the first conduit and introduced into the reactor at a substantially continuously controlled rate as the primary gas to the reactor. In response to an operational disturbance of the plant, the flow of gas in the first, second, and third conduits is terminated, and thereafter the pressure in the gas volume and in the reactor is substantially simultaneously reduced by opening pressure relief valves in the first and third conduits, and optionally by passing air directly from the second conduit to the turbine.

Interactive simulation system for artificial ventilation on the internet: virtual ventilator.

PubMed

Takeuchi, Akihiro; Abe, Tadashi; Hirose, Minoru; Kamioka, Koichi; Hamada, Atsushi; Ikeda, Noriaki

2004-12-01

To develop an interactive simulation system "virtual ventilator" that demonstrates the dynamics of pressure and flow in the respiratory system under the combination of spontaneous breathing, ventilation modes, and ventilator options. The simulation system was designed to be used by unexperienced health care professionals as a self-training tool. The system consists of a simulation controller and three modules: respiratory, spontaneous breath, and ventilator. The respiratory module models the respiratory system by three resistances representing the main airway, the right and left lungs, and two compliances also representing the right and left lungs. The spontaneous breath module generates inspiratory negative pressure produced by a patient. The ventilator module generates driving force of pressure or flow according to the combination of the ventilation mode and options. These forces are given to the respiratory module through the simulation controller. The simulation system was developed using HTML, VBScript (3000 lines, 100 kB) and ActiveX control (120 kB), and runs on Internet Explorer (5.5 or higher). The spontaneous breath is defined by a frequency, amplitude and inspiratory patterns in the spontaneous breath module. The user can construct a ventilation mode by setting a control variable, phase variables (trigger, limit, and cycle), and options. Available ventilation modes are: controlled mechanical ventilation (CMV), continuous positive airway pressure, synchronized intermittent mandatory ventilation (SIMV), pressure support ventilation (PSV), SIMV + PSV, pressure-controlled ventilation (PCV), pressure-regulated volume control (PRVC), proportional assisted ventilation, mandatory minute ventilation (MMV), bilevel positive airway pressure (BiPAP). The simulation system demonstrates in a graph and animation the airway pressure, flow, and volume of the respiratory system during mechanical ventilation both with and without spontaneous breathing. We developed a web application that demonstrated the respiratory mechanics and the basic theory of ventilation mode.

Beach nourishment alternative assessment to constrain cross-shore and longshore sediment transport

USGS Publications Warehouse

Karasu, Servet; Work, Paul A.; Uzlu, Ergun; Kankal, Murat; Yuksek, Omer

2016-01-01

A combined field and laboratory investigation was conducted to assess five options for creation of a recreational beach on a steep, armored shoreline on the eastern Black Sea coast. All designs incorporated a beach nourishment project placed between two existing, shore-normal, rubble-mound groins. Alternatives included the placement of a nearshore berm, longshore extensions added to the existing groins, and shore-parallel breakwaters. Several alternatives are reviewed for quantifying the performance of each design, including assessment of the change in shoreline position and project volume retained between the groins. Dimensionless benefits and benefit-cost ratios are quantified, and recommendations made on how to select the best outcome from a benefit-to-cost standpoint when options including hard structures are incorporated into a beach nourishment project design.

Hydrolysis and fractionation of lignocellulosic biomass

DOEpatents

Torget, Robert W.; Padukone, Nandan; Hatzis, Christos; Wyman, Charles E.

2000-01-01

A multi-function process is described for the hydrolysis and fractionation of lignocellulosic biomass to separate hemicellulosic sugars from other biomass components such as extractives and proteins; a portion of the solubilized lignin; cellulose; glucose derived from cellulose; and insoluble lignin from said biomass comprising one or more of the following: optionally, as function 1, introducing a dilute acid of pH 1.0-5.0 into a continual shrinking bed reactor containing a lignocellulosic biomass material at a temperature of about 94 to about 160.degree. C. for a period of about 10 to about 120 minutes at a volumetric flow rate of about 1 to about 5 reactor volumes to effect solubilization of extractives, lignin, and protein by keeping the solid to liquid ratio constant throughout the solubilization process; as function 2, introducing a dilute acid of pH 1.0-5.0, either as virgin acid or an acidic stream from another function, into a continual shrinking bed reactor containing either fresh biomass or the partially fractionated lignocellulosic biomass material from function 1 at a temperature of about 94-220.degree. C. for a period of about 10 to about 60 minutes at a volumetric flow rate of about 1 to about 5 reactor volumes to effect solubilization of hemicellulosic sugars, semisoluble sugars and other compounds, and amorphous glucans by keeping the solid to liquid ratio constant throughout the solubilization process; as function 3, optionally, introducing a dilute acid of pH 1.0-5.0 either as virgin acid or an acidic stream from another function, into a continual shrinking bed reactor containing the partially fractionated lignocellulosic biomass material from function 2 at a temperature of about 180-280.degree. C. for a period of about 10 to about 60 minutes at a volumetric flow rate of 1 to about 5 reactor volumes to effect solubilization of cellulosic sugars by keeping the solid to liquid ratio constant throughout the solubilization process; and as function 4, optionally, introducing a dilute acid of pH 1.0-5.0 either as virgin acid or an acidic stream from another function, into a continual shrinking bed reactor containing the partially fractionated lignocellulosic biomass material from function 3 at a temperature of about 180-280.degree. C. for a period of about 10 to about 60 minutes at a volumetric flow rate of about 1 to about 5 reactor volumes to effect solubilization of cellulosic sugars by keeping the solid to liquid ratio constant throughout the solubilization process.

Dosimetric benefits of automation in the treatment of lower thoracic esophageal cancer: Is manual planning still an alternative option?

PubMed

Li, Xiadong; Wang, Lu; Wang, Jiahao; Han, Xu; Xia, Bing; Wu, Shixiu; Hu, Weigang

2017-01-01

This study aimed to design automated volumetric-modulated arc therapy (VMAT) plans in Pinnacle auto-planning and compare it with manual plans for patients with lower thoracic esophageal cancer (EC). Thirty patients with lower thoracic EC were randomly selected for replanning VMAT plans using auto-planning in Pinnacle treatment planning system (TPS) version 9.10. Historical plans of these patients were then compared. Dose-volume histogram (DVH) statistics, dose uniformity, and dose homogeneity were analyzed to evaluate treatment plans. Auto-planning was superior in terms of conformity index (CI) and homogeneity index (HI) for planning target volume (PTV), significantly improving 8.2% (p = 0.013) and 25% (p = 0.007) compared with manual planning, respectively, and decreasing dose of heart and liver irradiated by 20 to 40 Gy and 5 to 30 Gy, respectively (p < 0.05). Meanwhile, auto-planning further reduced the maximum dose (D max ) of spinal cord by 6.9 Gy compared with manual planning (p = 0.000). Additionally, manual planning showed the significantly lower low-dose volume (V 5 ) for the lung (p = 0.005). For auto-planning, the V 5 of the lung was significantly associated with the relative volume index (the volume ratio of PTV to the lung), and the correlation coefficient (R) and p-value were 0.994 and 0.000. Pinnacle auto-planning achieved superior target conformity and homogeneity and similar target coverage compared with historical manual planning. Most of organs at risk (OARs) sparing was significantly improved by auto-planning except for the V 5 of the lung, and the low dose distribution was highly associated with PTV volume and lung volume in auto-planning. Copyright © 2017 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.

Space shuttle phase B extension, volume 1

NASA Technical Reports Server (NTRS)

1971-01-01

In order to define a system which would significantly reduce payload delivery costs, activities were extended to modifications of the reusable space shuttle design concept. Considered were systems using orbiters with external propellant tanks and an interim expendable booster which allowed phased development of the usable orbiter and booster. Analyzed were: Merits of internal and external propellant tanks and the impact of external LH2 compared to L02 and LH2; impact of cargo bay size; impact abort; merit of expendable booster options; and merit of a phased development program. Studies showed that external L02/LH2 and the continued use of the J-2S engine on the orbiter reduced program cost and risk.

Preliminary evaluation of crisis-relocation fallout-shelter options. Volume 2. Detailed analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Santini, D.J.; Clinch, J.M.; Davis, F.H.

1982-12-01

This report presents a preliminary, detailed evaluation of various shelter options for use if the President orders crisis relocation of the US urban population because of strong expectation of a nuclear war. The availability of livable shelter space at 40 ft/sup 2/ per person (congregate-care space) by state is evaluated. Options are evaluated for construction of fallout shelters allowing 10 ft/sup 2/ per person - such shelters are designed to provide 100% survival at projected levels of radioactive fallout. The FEMA concept of upgrading existing buildings to act as fallout shelters can, in principle, provide adequate shelter throughout most ofmore » the US. Exceptions are noted and remedies proposed. In terms of upgrading existing buildings to fallout shelter status, great benefits are possible by turning away from a standard national approach and adopting a more site-specific approach. Existing FEMA research provides a solid foundation for successful crisis relocation planning, but the program can be refined by making suitable modifications in its locational, engineering, and institutionally specific elements.« less

Options to avoid the second surgical site: a review of literature.

PubMed

Ramachandra, Srinivas Sulugodu; Rana, Ritu; Reetika, Singhal; Jithendra, K D

2014-09-01

As esthetics gain importance, periodontal plastic surgical procedures involving soft tissue grafts are becoming commoner both around natural teeth as well as around implants. Periodontal soft tissue grafts are primarily used for the purpose of root coverage and in pre-prosthetic surgery to thicken a gingival site or to improve the crestal volume. Soft tissue grafts are usually harvested from the palate. Periodontal plastic surgical procedures involving soft tissue grafts harvested from the palate have two surgical sites; a recipient site and another donor site. Many patients are apprehensive about the soft tissue graft procedures, especially the creation of the second/donor surgical site in the palate. In the past decade, newer techniques and products have emerged which provide an option for the periodontist/patient to avoid the second surgical site. MucoMatrixX, Alloderm(®), Platelet rich fibrin, Puros(®) Dermis and Mucograft(®) are the various options available to the practicing periodontist to avoid the second surgical site. Use of these soft tissue allografts in an apprehensive patient would decrease patient morbidity and increase patient's acceptance towards periodontal plastic surgical procedures.

A Review of Education and Training for Officers (RETO). Volume 2. Career Progression.

DTIC Science & Technology

1978-06-30

any control over the academic disciplines being pursued by scholarship students resulted in a few ROTC graduates with disciplines of no reasonable...direct application to the military environment. Providing scholarship winners a list of academic majors from which to choose and thereafter channel their... academic endeavors, would provide a better link between precommissioning education and known Army requirements. (2) introducing a "pay-back" option

Proceedings: Outer Planet Probe Technology Workshop, summary volume

NASA Technical Reports Server (NTRS)

1974-01-01

A summary report and overview of the Outer Planet Probe Technology Conference are given. Summary data cover: (1) state of the art concerning mission definitions, probe requirements, systems, subsystems, and mission peculiar hardware, (2) mission and equipment trade-offs associated with Saturn/Uranus baseline configuration and the influence of Titan and Jupiter options on mission performance and costs, and (3) identification of critically required future R and D activities.