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Sample records for organicheskikh soedinenij iz

  1. Near-contact Binaries IZ Monocerotis and AR Draconis

    NASA Astrophysics Data System (ADS)

    Yang, Yuan-Gui; Dai, Hai-Feng; Zhou, Zheng; Li, Qun

    2016-05-01

    We present multi-color photometric observations for two neglected near-contact binaries, IZ Mon (P=0\\_\\_AMP\\_\\_fd;77980) and AR Dra (P=0\\_\\_AMP\\_\\_fd;67584). By the aid of the updated W-D analysis code, the photometric solutions were deduced from the multi-color light curves (LCs). IZ Mon is a semi-detached binary with a mass ratio of q=0.388(+/- 0.002), while AR Dra is a detached star with a mass ratio of q=0.652(+/- 0.002). The asymmetric LCs of IZ Mon were modeled by a hot spot on the secondary’s surface, which may be attributed to mass transfer from the primary. Based on all collected eclipse times for two systems, we constructed their timing residual curves. The orbital period for IZ Mon may be continuously decreasing at a rate of {dP}/{dt}=-2.06(+/- 0.04) {days} {{yr}}-1, which may result from mass and angular momentum loss from the central system. For AR Dra, there exists a cyclic variation with a period of {P}3=104.9(+/- 2.9) {yr} due to light-time orbit effect via the presence of the third body, whose mass is more than 0.28(+/- 0.02) {M}⊙ . Finally, two near-contact binaries, IZ Mon and AR Dra, will evolve into contact binaries.

  2. Radio evolution of supernova SN 2008iz in M 82

    NASA Astrophysics Data System (ADS)

    Kimani, N.; Sendlinger, K.; Brunthaler, A.; Menten, K. M.; Martí-Vidal, I.; Henkel, C.; Falcke, H.; Muxlow, T. W. B.; Beswick, R. J.; Bower, G. C.

    2016-08-01

    We report on multi-frequency Very Large Array (VLA) and Very Long Baseline Interferometry (VLBI) radio observations for a monitoring campaign of supernova SN 2008iz in the nearby irregular galaxy M 82. We fit two models to the data, a simple time power-law, S ∝ tβ, and a simplified Weiler model, yielding decline indices of β = -1.22 ± 0.07 (days 100-1500) and -1.41 ± 0.02 (days 76-2167), respectively. The late-time radio light-curve evolution shows flux-density flares at ~970 and ~1400 days that are a factor of ~2 and ~4 higher than the expected flux, respectively. The later flare, except for being brighter, does not show signs of decline at least from results examined so far (2014 January 23; day 2167). We derive the spectral index, α, S ∝ να for frequencies 1.4 to 43 GHz for SN 2008iz during the period from ~430 to 2167 days after the supernova explosion. The value of α shows no signs of evolution and remains steep ≈-1 throughout the period, unlike that of SN 1993J, which started flattening at ~day 970. From the 4.8 and 8.4 GHz VLBI images, the supernova expansion is seen to start with a shell-like structure that becomes increasingly more asymmetric, then breaks up in the later epochs, with bright structures dominating the southern part of the ring. This structural evolution differs significantly from SN 1993J, which remains circularly symmetric over 4000 days after the explosion. The VLBI 4.8 and 8.4 GHz images are used to derive a deceleration index, m, for SN 2008iz, of 0.86 ± 0.02, and the average expansion velocity between days 73 and 1400 as (12.1 ± 0.2) × 103 km s-1. From the energy equipartition between magnetic field and particles, we estimate the minimum total energy in relativistic particles and the magnetic fields during the supernova expansion and also find the magnetic field amplification factor for SN 2008iz to be in the range of 55-400. The VLBI images (FITS files) are only available at the CDS via anonymous ftp to http

  3. VizieR Online Data Catalog: BVR photometry of IZ Mon and AR Dra (Yang+, 2016)

    NASA Astrophysics Data System (ADS)

    Yang, Y.-G.; Dai, H.-F.; Zhou, Z.; Li, Q.

    2016-07-01

    CCD Photometry for IZ Mon and AR Dra, was acquired using the 60cm telescope and the 85cm telescope at the Xinglong station (XLs) of National Astronomical Observatories of China (NAOC). Two telescopes are equipped with the standard Johnson-Cousins UBVRcIc. filters. We then obtained the individual observations as heliocentric Julian dates and differential magnitude, which are listed in Table1. The complete light curves for IZ Mon were obtained on 2009 January 20, 22, 24, 25, and 26, and March 1, using the 85cm telescope. The exposure times are fixed to be 20, 15, and 15s for BVR bands, respectively. A total of 961, 960, and 959 effective images in BVR bands are obtained. Another primary eclipse for IZ Mon was monitored on 2011 January 17. AR Dra was observed on 2009 February 20, 25, 26, and 27, with the 65cm telescope. The typical exposure times are 50, 40 and 40s for BVR bands, which depend on the condition of weather. In total, we obtained 733, 728 and 356 images in B, V and R bands, respectively. (6 data files).

  4. Copolymerization of Propylene and Polar Monomers Using Pd/IzQO Catalysts.

    PubMed

    Nakano, Ryo; Nozaki, Kyoko

    2015-09-02

    Palladium catalysts bearing imidazo[1,5-a]quinolin-9-olate-1-ylidene (IzQO) ligands polymerize α-olefins while incorporating polar monomers. The steric environment provided by N-heterocyclic-carbene (NHC) enables regioselective insertion of α-olefins and polar monomers, yielding polypropylene, propylene/allyl carboxylate copolymers, and propylene/methyl acrylate copolymer. Known polymerization catalysts bearing NHC-based ligands decompose rapidly, whereas the present catalyst is durable because of structural confinement, wherein the NHC-plane is coplanar to the metal square plane. The present catalyst system enables facile access to a new class of functionalized polyolefins and helps conceive a new fundamental principle for designing NHC-based ligands.

  5. 76 FR 73760 - In the Matter of the Designation of Imad Fa'iz Mughniyah also Known as Imad Fayiz Mughniyah as a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE In the Matter of the Designation of Imad Fa'iz Mughniyah also Known as Imad Fayiz Mughniyah as a Specially Designated Global Terrorist Pursuant to Section 1(b) of Executive Order 13224, as Amended In accordance with section 1(b) of Executive Order 13224,...

  6. Response of lake water quality to wastewater inputs from land-based fish farm located on Yuvarlakçay Creek in Köyceğiz-Dalyan Specially Protected Area, Turkey.

    PubMed

    Taşeli, B K

    2009-10-01

    Köyceğiz Lake is located in the south-western part of Turkey. The area between the Köyceğiz Lake and the Mediterranean Sea is covered with four small lakes and several canals. The surroundings of the lake, canals and forests have a great potential as a reproduction areas for Mediterranean Sea turtles (Caretta caretta) and sheltering place for various animals. In the vicinity of this system there are agricultural areas and small settlements. In this region the most important economic activities are tourism and fisheries. However, the lake is currently threatened by pollution because of (1) non-point source pollution (agriculture); (2) point sources (land-based fish farms); (3) inefficient sewerage systems; (4) uncontrolled soil erosion in its drainage basin; (5) inappropriate flood control measures; and (6) channel traffic. This study evaluates the influence of its influent creeks namely Namnam and Yuvarlakçay Creek on the water quality of Köyceğiz Lake, mainly because the creeks are believed to be responsible for the major pollutant load reaching the lake. Accordingly, this study demonstrates (1) change in the water quality of Köyceğiz Lake from 2006 to 2007; (2) the water quality classification of the major influent creeks feeding Köyceğiz Lake; and (3) how land-based fish farm influences Yuvarlakçay Creek water quality in a Köyceğiz-Dalyan Specially Protected Area.

  7. Earthquake-induced soft-sediment deformations and seismically amplified erosion rates recorded in varved sediments of Köyceğiz Lake (SW Turkey)

    NASA Astrophysics Data System (ADS)

    Avşar, Ulaş; Jónsson, Sigurjón; Avşar, Özgür; Schmidt, Sabine

    2016-06-01

    Earthquake-triggered landslides amplify erosion rates in catchments, i.e., catchment response (CR) to seismic shocks. In addition to historical eyewitness accounts of muddy rivers implying CRs after large earthquakes, several studies have quantitatively reported increased sediment concentrations in rivers after earthquakes. However, only a few paleolimnological studies could detect CRs within lacustrine sedimentary sequences as siliciclastic-enriched intercalations within background sedimentation. Since siliciclastic-enriched intercalations can easily be of nonseismic origin, their temporal correlation with nearby earthquakes is crucial to assign a seismic triggering mechanism. In most cases, either uncertainties in dating methods or the lack of recent seismic activity has prevented reliable temporal correlations, making the seismic origin of observed sedimentary events questionable. Here we attempt to remove this question mark by presenting sedimentary traces of CRs in the 370-year-long varved sequence of Köyceğiz Lake (SW Turkey) that we compare with estimated peak ground acceleration (PGA) values of several nearby earthquakes. We find that earthquakes exceeding estimated PGA values of ~20 cm/s2 can induce soft-sediment deformations, while CRs seem only to be triggered by PGA levels higher than 70 cm/s2. In Köyceğiz Lake, CRs produce Cr- and Ni-enriched sedimentation due to the seismically mobilized soils derived from ultramafic rocks in the catchment. Given the varve chronology, the residence time of the seismically mobilized material in the catchment is determined to be 5 to 10 years.

  8. [Study of acute vulvovaginitis in sexually active adult women, with special reference to candidosis, in patients of the Francisco J. Muñiz Infectious Diseases Hospital].

    PubMed

    Buscemi, Luis; Arechavala, Alicia; Negroni, Ricardo

    2004-12-01

    The results of microbiological vaginal secretions samples obtained from 749 women (from July 2001 to July 2002) were studied in the Bacteriology Unit of the Francisco Javier Muñiz Hospital from Buenos Aires. All patients suffered acute vulvovaginitis were child bearing and sexually active women, 334 of them were HIV-positive. The following are the results of the microbiological studies: Lactobacillus spp 50.6%, Gardnerella vaginalis 25.6%, Candida spp 17.4%, Trichomonas vaginalis 5.3%, Neisseria gonorrhoeae 0.3% and B group Streptococcus 0.8%. Candida vaginitis was significantly more frequent in HIV-positive patients, (21.6% vs 14%; p = 0.0086); meanwhile, trichomoniasis was less common although the difference was not statistically significant (3.6 vs 6.7%, p = 0.0810). The following Candida species were isolated in this study: Candida albicans 76.8%, Candida glabrata 15.6%, Candida parapsilosis 2.9%, Candida tropicalis 1.5% and Candida krusei 0.7%. Eight cases (6.2%) of vaginitis were produced by two Candida species (C. albicans and C. glabrata), and in three cases (2.17%) Saccharomyces cerevisiae were isolated. Five women suffering acute vaginitis with Candida spp presented another etiologic agent of vaginal infection, three cases T. vaginalis and two cases G. vaginalis. The following are some of the most important findings of this study: 1) Half of the patients presented a normal microbial biota; 2) Candida spp vaginitis was significantly more frequent among HIV-positive women; 3) we observed a high incidence of Candida glabrata infections (15.9%), 4) 6.2% of vaginal candidiasis were caused by more than one Candida species and, 5) the susceptibility pattern of C. albicans and C. glabrata isolates against fluconazole was similar to the one observed in other studies. The majority of C. albicans isolates were susceptible to fluconazole (MIC90 = 0.5 microg/ml) meanwhile C. glabrata strains were much less susceptible to this drug (MIC50 and MIC90 = 32 microg/ml).

  9. The Toxicology of Organic Compounds of Tin (A Survey of the Literature) (Toksikologiya Organicheskikh Soedienii Olova (Obzor Literatury)),

    DTIC Science & Technology

    TIN COMPOUNDS, TOXICITY), (*TIN, ORGANIC COMPOUNDS), DOSAGE, RESPIRATION, BIOASSAY, RESPIRATORY SYSTEM, PATHOLOGY, MORTALITY RATES , PATHOLOGY...HISTOLOGY, MORTALITY RATES , LUNG, KIDNEYS, EDEMA, SKIN(ANATOMY), NERVOUS SYSTEM, HEMOPOIETIC SYSTEM, PHYSIOLOGY, ENZYMES, INDUSTRIAL MEDICINE, USSR

  10. Forest Vegetation as a Source of Biogenic and Organic Substances in Natural Inland Waters (Drevesnaya Rastitel’nosti Kak Istochnik Biogenn’ikh i Organicheskikh Veshestv v Prirodn’ikh Vodoemakh),

    DTIC Science & Technology

    1977-03-01

    especially of organic and ammonium nitrogen phosphorus, carbohydrates and aminoacids than coniferous ones (pine). The data obtained can be used when predicting the conditions of new and existing water basins. (Author)

  11. Remedial Investigation Addendum Report Data Item A009. Volume 4: Appendices I-Z

    DTIC Science & Technology

    1993-12-01

    wetland. Functions and values were evaluated in a Level 2 WET assessment, which is generally considered to be a reasonable balance between time, available...spp. Bog Hemp Boehmeria cylindrica FACW+ Water Shield Brasenia schreberi OBL Coontail Ceratophyllum demersum OBL’) Goldthread Coptis trifolia FACW...having a better balance of number of organisms (abundance) per number of taxa. This also suggests that Cold Spring Brook Pond may be impacted relative

  12. Production of alcohol from Jerusalem artichoke for gasoline additive. Proucavanje mogucnosti proizvodnje alkohola iz topinambura kao dodatka u benzin

    SciTech Connect

    Pekic, B.; Kisgeci, J.

    1984-01-01

    Trials conducted in 1980 and 1981 on three soil types, chernozem (a rich soil), anthropogenized black sand (a medium-rich soil), and anthropogenized brown sand (a poor soil), showed that the Jerusalem artichoke was superior to conventional field crops (corn, sugarbeet, potato, and sorghum) regarding the yield of carbohydrates per unit area, especially when grown on the poor soil. The analyses of the technological properties of Jerusalem artichokes grown for two years in the experimental plots showed that the plant species is a quality raw material for the production of alcohol. From the aspect of alcohol production, the quality of the tested varieties of Jerusalem artichoke depended neither on soil quality nor on the delay in harvesting the crop after it reached technological maturity. The results of the study indicate that the alcohol production from Jerusalem artichokes would be more economic, i.e., more profitable, than the production from conventional raw materials. The study of the carbohydrate composition of Jerusalem artichoke tubers made it clear that besides alcohol production, Jerusalem artichokes are a good raw material for the production of high-fructose syrup and crystalline fructose. Since the interest in these products kept increasing in recent years, because of their exceptional characters, it is necessary to establish research programs to cover these field too. In the course of the study the authors came across some interesting literature data on the use of Jerusalem artichokes as a raw material for the production of high-fructose syrup and crystalline fructose. Some of the publication, i.e., those that might be useful in further research work, are appended to this study.

  13. Structure modeling and growing AgClхBr1-х, Ag1-xTlxBr1-xIx, and Ag1-xTlxClyIzBr1-y-z crystals for infrared fiber optics

    NASA Astrophysics Data System (ADS)

    Korsakov, Alexandr; Zhukova, Liya; Korsakova, Elena; Zharikov, Evgenii

    2014-01-01

    In this paper we describe the aggregate technology of producing variable composition crystals, based on the solid solutions of silver and Tl+-doped halides for creating infrared photonic crystal fibers in the spectral range of 2-40 μm by extruding, we also produce all the necessary equipment. We specified the minimum melting point position for the AgCl-AgBr phase diagram. We also investigated the fundamental physical properties of new crystals and fibers: transmission losses, transmission range, refraction index, hardness, and density.

  14. Growth Disorders

    MedlinePlus

    ... well — the condition is called hypopituitarism (say: hy-po-pih-TOO-eh-ter-iz-em). This can ... little, the condition is called hypothyroidism (say: hy-po-THY-royd-iz-em). Having too little thyroxine ...

  15. Silver bullet or trojan horse? The effects of inclusionary zoning on local housing markets in the United States.

    PubMed

    Schuetz, Jenny; Meltzer, Rachel; Been, Vicki

    2011-01-01

    Many local governments are adopting inclusionary zoning (IZ) as a means of producing affordable housing without direct public subsidies. In this paper, panel data on IZ in the San Francisco metropolitan area and suburban Boston are used to analyse how much affordable housing the programmes produce and how IZ affects the prices and production of market-rate housing. The amount of affordable housing produced under IZ has been modest and depends primarily on how long IZ has been in place. Results from suburban Boston suggest that IZ has contributed to increased housing prices and lower rates of production during periods of regional house price appreciation. In the San Francisco area, IZ also appears to increase housing prices in times of regional price appreciation, but to decrease prices during cooler regional markets. There is no evidence of a statistically significant effect of IZ on new housing development in the Bay Area.

  16. A taxonomic monograph of the leaf-litter inhabiting weevil genus Plumolepilius new genus (Coleoptera: Curculionidae: Molytinae: Conotrachelini) from Mexico, Guatemala, and El Salvador.

    PubMed

    Barrios-Izás, Manuel A; Anderson, Robert S; Morrone, Juan J

    2016-09-14

    We describe the Mesoamerican leaf litter weevil genus Plumolepilius Barrios-Izás & Anderson, new genus (Coleoptera: Curculionidae: Molytinae: Conotrachelini) (type species P. trifiniensis Barrios-Izás & Anderson, new species), species of which inhabit mountain ecosystems from the state of Chiapas in southeastern Mexico to northern Panama. In this paper we describe nine new species from Mexico, Guatemala, and El Salvador: P. trifiniensis Barrios-Izás & Anderson, new species (El Salvador and Guatemala); P. branstetteri Barrios-Izás & Anderson, new species (Guatemala and Mexico); P. longinoi Barrios-Izás & Anderson, new species (Guatemala and Mexico); P. cortezi Barrios-Izás & Anderson, new species (Guatemala and Mexico); P. canoi Barrios-Izás & Anderson, new species (Guatemala); P. schusteri Barrios-Izás & Anderson, new species (Guatemala and Mexico); P. daryi Barrios-Izás & Anderson, new species (Guatemala); P. yolnabajensis Barrios-Izás & Anderson, new species (Guatemala); and P. macalajauensis Barrios-Izás & Anderson, new species (Guatemala).        The genus and the species are named and described, information on their geographical distributions is given and images of the habitus of both sexes and the aedeagus are presented. A key to the species of Plumolepilius based on males is included.        The monophyly of Plumolepilius was confirmed by a parsimony analysis of external and male aedeagus morphology and the genus is best characterized by the presence of plumose scales lining the prosternal channel. Phylogenetic analysis supports that Lepilius Champion 1905 is the sister genus of Plumolepilius.

  17. Is Inclusionary Zoning Inclusionary? A Guide for Practitioners. Technical Report

    ERIC Educational Resources Information Center

    Schwartz, Heather L.; Ecola, Liisa; Leuschner, Kristin J.; Kofner, Aaron

    2012-01-01

    Inclusionary zoning (IZ) has become an increasingly popular tool for providing affordable housing in an economically integrative manner. IZ policies typically require developers to set aside a proportion of units in market-rate residential developments to be made affordable for lower-income households in exchange for development rights or zoning…

  18. Characterizing and Quantifying Local and Regional Particulate Matter Emissions From Department of Defense Installations

    DTIC Science & Technology

    2005-01-07

    Elza Cushing and Hector Moldanado also of the Directorate of the Environment helped us out in numerous ways. The personnel of...0.51 0 0.2 0.4 0.6 0.8 1 1.2 1.4 1.6 1.8 2 0 1 2 3 4 Disturbance Level N or m al iz ed q /u * Figure 4.31. The observed relationship between...al iz ed q /u * Without sand feed N or m al iz ed q /u * N or m al iz ed q /u * 0 0 1 2 3 4 Disturbance Level N or m al iz ed q /u *

  19. New Conceptual Model for Soil Treatment Units: Formation of Multiple Hydraulic Zones during Unsaturated Wastewater Infiltration.

    PubMed

    Geza, Mengistu; Lowe, Kathryn S; Huntzinger, Deborah N; McCray, John E

    2013-07-01

    Onsite wastewater treatment systems are commonly used in the United States to reclaim domestic wastewater. A distinct biomat forms at the infiltrative surface, causing resistance to flow and decreasing soil moisture below the biomat. To simulate these conditions, previous modeling studies have used a two-layer approach: a thin biomat layer (1-5 cm thick) and the native soil layer below the biomat. However, the effect of wastewater application extends below the biomat layer. We used numerical modeling supported by experimental data to justify a new conceptual model that includes an intermediate zone (IZ) below the biomat. The conceptual model was set up using Hydrus 2D and calibrated against soil moisture and water flux measurements. The estimated hydraulic conductivity value for the IZ was between biomat and the native soil. The IZ has important implications for wastewater treatment. When the IZ was not considered, a loading rate of 5 cm d resulted in an 8.5-cm ponding. With the IZ, the same loading rate resulted in a 9.5-cm ponding. Without the IZ, up to 3.1 cm d of wastewater could be applied without ponding; with the IZ, only up to 2.8 cm d could be applied without ponding. The IZ also plays a significant role in soil moisture distribution. Without the IZ, near-saturation conditions were observed only within the biomat, whereas near-saturation conditions extended below the biomat with the IZ. Accurate prediction of ponding is important to prevent surfacing of wastewater. The degree of water and air saturation influences pollutant treatment efficiency through residence time, volatility, and biochemical reactions.

  20. Further Programs for the Solution of Large Sparse Systems of Linear Equations

    DTIC Science & Technology

    1975-08-01

    IY = IX Oi+6 HO iY = RY(IY) 047 IF (IY.E0.1X) GO TO 70 OHO ll - IY 049 bu il = CY(IZ) ObO IF (I^.GT.N) GO TO 60 Obi K = ^+1 0b2 IE(K...IY 0b3 IH(K) : ll ObH IMO(IZ) = ND(IZ)-1 „ Ubb bO IF (CYUZ).N£.IY) Gü TO 50 Ob6 CY(IZ) = CY(IY) 0b7 CY’. IY) = MM Ob6 MM = IY Ob9 <JO TO...ND( ll ) = NÜ(I1)+1 110 NÜ(12) = NÜ(I2)+1 111 MD(7) = Mü(7)+1 IF (MM Nt.O) GO TO 170 USE NEw STOHAGE 112 113 C 11ɜ Mü(b) = Mü(6)+1 lib IF (MD

  1. What Are Normal Puberty, Precocious Puberty, and Delayed Puberty?

    MedlinePlus

    ... a long-lasting condition known as hypogonadism (pronounced HI-poe-GO-nad-iz-uhm ) in which the ... Turner syndrome or in individuals with hypogonadotropic (pronounced HI-po-GO-nah-doe-TROH-pik ) hypogonadism, which ...

  2. Myofascial trigger points and innervation zone locations in upper trapezius muscles

    PubMed Central

    2013-01-01

    Background Myofascial trigger points (MTrPs) are hyperirritable spots located in taut bands of muscle fibres. Electrophysiological studies indicate that abnormal electrical activity is detectable near MTrPs. This phenomenon has been described as endplate noise and it has been purported to be associated MTrP pathophysiology. Thus, it is suggested that MTrPs will be overlap the innervation zone (IZ). The purpose of this work was to describe the location of MTrPs and the IZ in the right upper trapezius. Methods We screened 71 individuals and eventually enrolled 24 subjects with neck pain and active MTrPs and 24 neck pain-free subjects with latent MTrPs. Surface electromyography (sEMG) signals were detected using an electrode matrix during isometric contraction of the upper trapezius. A physiotherapist subsequently examined the subject’s trapezius to confirm the presence of MTrPs and establish their location. IZ locations were identified by visual analysis of sEMG signals. IZ and MTrPs locations were described using an anatomical coordinate system (ACS), with the skin area covered by the matrix divided into four quadrants. Results No significant difference was observed between active and latent MTrPs locations (P = 0.6). Forty-five MTrPs were in the third quadrant of the ACS, and 3 were included in second quadrant. IZs were located approximately midway between the seventh cervical vertebrae and the acromial angle in a limited area in the second and third quadrants. The mean distance between MTrP and IZ was 10.4 ± 5.8 mm. Conclusions According to the acquired results, we conclude that IZ and MTrPs are located in well-defined areas in upper trapezius muscle. Moreover, MTrPs in upper trapezius are proximally located to the IZ but not overlapped. PMID:23758854

  3. Parallel Processing Applied to Computational Electromagnetics

    DTIC Science & Technology

    1991-10-01

    equations results, where N = NB + NW + NJ. IZ881 Wiz84’]II81 P [E81 1 EZW ] [ZWW] [ZW] [wl =[ [EWl (3-22) Iz’ rI [z’Wl IJ I [FI_ [E IJ where Z is the...was an array of four transputers on a motherboard that co . 1d be installed inside a PC. This decision was based on the low cost, ease of use, and

  4. Microstructural Evolution of the Interdiffusion Zone between U-9 Wt Pct Mo Fuel Alloy and Zr-1 Wt Pct Nb Cladding Alloy Upon Annealing

    NASA Astrophysics Data System (ADS)

    Neogy, S.; Laik, A.; Saify, M. T.; Jha, S. K.; Srivastava, D.; Dey, G. K.

    2017-03-01

    Diffusion couple formed between U-9 wt pct Mo and Zr-1 wt pct Nb alloys, proposed as fuel and clad materials, respectively, in nuclear research reactors, was annealed to investigate the microstructural evolution of the interdiffusion zone (IZ) as a function of temperature. A layered-type IZ microstructure was observed, the mechanism of development of which was elucidated. Mo2Zr phase, present as dispersoids, in the U-rich part of the as-bonded IZ evolved into a continuous layer and into a "massive" morphology upon annealing. The discontinuous precipitation reaction in the matrix adjoining the Mo2Zr phase, instigated by Mo depletion, generated lamellae of α-U phase within the γ-U(Mo,Zr) matrix. Zr-rich α-Zr(U) precipitates were observed in U-rich U-Mo-Zr matrix in the IZ next to the U-9Mo base material due to the clustering tendency of the matrix phase. The IZ next to Zr-1Nb base material comprised a "basket weave" microstructure of α-Zr laths with β-Zr(Nb,U) interlath boundaries, wherein an omega like transformation of the latter to δ-UZr2 was also noticed. The growth rates of the IZ were orders of magnitude lower when compared with the ones reported between the compositionally similar U-10 wt pct Mo alloy and the presently used Al or Al-Si cladding alloys.

  5. Relationship between innervation zone width and mean muscle fiber conduction velocity during a sustained isometric contraction

    PubMed Central

    Ye, X.; Beck, T.W.; Wages, N.P.

    2015-01-01

    Objectives: To examine the relationship between the biceps brachii muscle innervation zone (IZ) width and the mean muscle fiber conduction velocity (MFCV) during a sustained isometric contraction. Methods: Fifteen healthy men performed a sustained isometric elbow flexion exercise at their 60% maximal voluntary contraction (MVC) until they could not maintain the target force. Mean MFCV was estimated through multichannel surface electromyographic recordings from a linear electrode array. Before exercise, IZ width was quantified. Separate non-parametric one-way analyses of variance (ANOVAs) were used to examine whether there was a difference in each mean MFCV variable among groups with different IZ width. In addition, separate bivariate correlations were also performed to examine the relationships between the IZ width and the mean MFCV variables during the fatiguing exercise. Results: There was a significant difference in the percent decline of mean MFCV (%ΔMFCV) among groups with different IZ width (χ2 (3)=11.571, p=0.009). In addition, there was also a significant positive relationship between the IZ width and the %ΔMFCV (Kendall’s tau= 0.807; p<0.001). Conclusions: We believe that such relationship is likely influenced by both muscle fiber size and the muscle fiber type composition. PMID:25730657

  6. Three-Dimensional Innervation Zone Imaging from Multi-Channel Surface EMG Recordings.

    PubMed

    Liu, Yang; Ning, Yong; Li, Sheng; Zhou, Ping; Rymer, William Z; Zhang, Yingchun

    2015-09-01

    There is an unmet need to accurately identify the locations of innervation zones (IZs) of spastic muscles, so as to guide botulinum toxin (BTX) injections for the best clinical outcome. A novel 3D IZ imaging (3DIZI) approach was developed by combining the bioelectrical source imaging and surface electromyogram (EMG) decomposition methods to image the 3D distribution of IZs in the target muscles. Surface IZ locations of motor units (MUs), identified from the bipolar map of their MU action potentials (MUAPs) were employed as a prior knowledge in the 3DIZI approach to improve its imaging accuracy. The performance of the 3DIZI approach was first optimized and evaluated via a series of designed computer simulations, and then validated with the intramuscular EMG data, together with simultaneously recorded 128-channel surface EMG data from the biceps of two subjects. Both simulation and experimental validation results demonstrate the high performance of the 3DIZI approach in accurately reconstructing the distributions of IZs and the dynamic propagation of internal muscle activities in the biceps from high-density surface EMG recordings.

  7. Accuracy of three different techniques for automatically estimating innervation zone location.

    PubMed

    Beck, Travis W; DeFreitas, Jason M; Stock, Matt S

    2012-01-01

    The purpose of this study was to compare the accuracy of the estimated innervation zone (IZ) locations obtained from cross-correlation, the minimum amplitude, and maximum center frequency criteria. Eight healthy men (mean±SD age=23.0±4.3 yrs) performed isometric muscle actions of the leg extensors, and 15 separate bipolar surface electromyographic (EMG) signals were detected from the vastus lateralis. A custom software program was used to estimate the location of the IZ based on: (1) the EMG channel that demonstrated the lowest amplitude, (2) the EMG channel that showed the highest mean frequency, and (3) the EMG channel that demonstrated the lowest peak cross-correlation between the signals from adjacent channels. The IZ location estimates from the lowest amplitude and highest mean frequency criteria were accurate in only 43.75% and 7.5% of the cases, respectively. The accuracy of the cross-correlation-based method was 90%. The cross-correlation-based method was much more accurate for estimating IZ location than were the lowest amplitude and highest mean frequency criteria. Cross-correlation could potentially be used for estimating the location of the IZ without the need for visual inspection of EMG signals.

  8. Numerical Field Model Simulation of Full-Scale Fire Tests in a Closed Spherical/Cylindrical Vessel with Internal Ventilation

    DTIC Science & Technology

    1988-09-01

    NCHPJtl10),KCHPB( 10), 00045600 8 NCHPK)10), TCHP (101,CPS(10),CONSI1O),WFAN 10) 00045700 COtttON/SL31/ TOD(22,16,32),R00(ZZ,16,3Z),P0D(22,16,32...JCHPBIN),NCHPJIN),KCHPB(N), 00050000 a NCHPK(N) , TCHP (N J,CPS(N I,&EFAN(N J ,CON N I 00050100 10 FORMAT 12X,’N: ’,12,1 ICHPB: 1,IZ, NCHPI: ’PI2, I JCHPB...12, 00050200 & NCHPJz 1,I2, 1 KCHPB= ,IZ, NCHPK: ’,IZ, I TCHP = 1,F8.5, 00050300 &’ CPS= 1,F8.5,/, I FAN x ’,F1Z.5, ° CONS= ’,F12.5,/) 00050400 19

  9. Use of biomarkers in resident organisms as a tool for environmental monitoring in a cold coastal system, Tierra del Fuego Island.

    PubMed

    Comoglio, L; Amin, O; Botté, S; Marcovecchio, J

    2011-03-01

    Antioxidant status of Nacella (P) magellanica and Mytilus edulis related with heavy metal in sediment and tissues were analysed in five stations close to Ushuaia city in winter and spring. The principal component analysis produced a two-dimensional pattern of the degree of similarity between sites. The Industrial-Urban Contamination Index (IUCI) showed that the Industrial Zone (IZ) and Oil Marine Station (OMS) represent areas with anthropic inputs. Heavy metals have differential association with biomarkers depending on the species. In limpets, digestive gland presented major activities of enzyme defence in winter and gonads have shown higher values of Catalase (CAT) during spring while lipid peroxidation (LPO) presented higher values in IZ. For mussels CAT and LPO increased in spring time. For superoxide dismutase (SOD) peaks have been detected in IZ and NW stations for winter. Differences in biomarker responses due to seasons did not influence the grouping of the sites into references and contaminated groups.

  10. Innervation zones of fasciculating motor units: observations by a linear electrode array.

    PubMed

    Jahanmiri-Nezhad, Faezeh; Barkhaus, Paul E; Rymer, William Z; Zhou, Ping

    2015-01-01

    This study examines the innervation zone (IZ) in the biceps brachii muscle in healthy subjects and those with amyotrophic lateral sclerosis (ALS) using a 20-channel linear electromyogram (EMG) electrode array. Raster plots of individual waveform potentials were studied to estimate the motor unit IZ. While this work mainly focused on fasciculation potentials (FPs), a limited number of motor unit potentials (MUPs) from voluntary activity of 12 healthy and seven ALS subjects were also examined. Abnormal propagation of MUPs and scattered IZs were observed in fasciculating units, compared with voluntarily activated MUPs in healthy and ALS subjects. These findings can be related to muscle fiber reinnervation following motor neuron degeneration in ALS and the different origin sites of FPs compared with voluntary MUPs.

  11. Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction.

    PubMed

    Jugdutt, Bodh I; Idikio, Halliday; Uwiera, Richard R E

    2007-09-01

    To determine whether therapy with the angiotensin II type 1 receptor blocker (ARB) candesartan and the comparator angiotensin-converting-enzyme inhibitor (ACEI) enalapril during healing after reperfused ST-elevation myocardial infarction (RSTEMI) limit adverse remodeling of infarct zone (IZ) collagens and left ventricular (LV) diastolic dysfunction, we randomized 24 dogs surviving anterior RSTEMI (90-min coronary occlusion) to placebo, candesartan, and enalapril therapy between day 2 and 42. Six other dogs were sham. We measured regional IZ and non-infarct zone (NIZ) collagens (hydroxyproline; types I/III; cross-linking), transforming growth factor-beta (TGF-beta) and topography at 6 weeks, and hemodynamics, LV diastolic and systolic function, and remodeling over 6 weeks. Compared to sham, placebo-RSTEMI differentially altered regional collagens, with more pronounced increase in TGF-beta, hydroxyproline, and type I, insoluble, and cross-linked collagens in the IZ than NIZ, and increased IZ soluble and type III collagens at 6 weeks, and induced persistent LV filling pressure elevation, diastolic and systolic dysfunction, and LV remodeling over 6 weeks. Compared to placebo-RSTEMI, candesartan and enalapril limited adverse regional collagen remodeling, with normalization of type III, soluble and insoluble collagens and decrease in pyridinoline cross-linking in the IZ at 6 weeks, and attenuation of LV filling pressure, diastolic dysfunction, and remodeling over 6 weeks. The results suggest that candesartan and enalapril during healing after RSTEMI prevent rather than worsen adverse remodeling of IZ collagens and LV diastolic dysfunction, supporting the clinical use of ARBs and ACEIs during subacute RSTEMI.

  12. Optimization of Breast Tomosynthesis Imaging Systems for Computer-Aided Detection

    DTIC Science & Technology

    2011-05-01

    11 4 Artifacts in the periodogram . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 5 Comparison of clinical and phantom data...phantom onto a 100-micron detector led to artifacts in the periodograms (see Fig. 4), so we were restricted to projecting the 500-micron phantoms onto... periodogram , and power spectrum. 13 Cl in ic al d at a 1- cm R O I s iz e Ph an to m d at a 3. 2- cm R O I s iz e Cl in ic al d at a 3. 2- cm R O

  13. Detection of Multiple Innervation Zones from Multi-Channel Surface EMG Recordings with Low Signal-to-Noise Ratio Using Graph-Cut Segmentation

    PubMed Central

    Farahi, Morteza; Rojas, Monica; Mañanas, Miguel Angel; Farina, Dario

    2016-01-01

    Knowledge of the location of muscle Innervation Zones (IZs) is important in many applications, e.g. for minimizing the quantity of injected botulinum toxin for the treatment of spasticity or for deciding on the type of episiotomy during child delivery. Surface EMG (sEMG) can be noninvasively recorded to assess physiological and morphological characteristics of contracting muscles. However, it is not often possible to record signals of high quality. Moreover, muscles could have multiple IZs, which should all be identified. We designed a fully-automatic algorithm based on the enhanced image Graph-Cut segmentation and morphological image processing methods to identify up to five IZs in 60-ms intervals of very-low to moderate quality sEMG signal detected with multi-channel electrodes (20 bipolar channels with Inter Electrode Distance (IED) of 5 mm). An anisotropic multilayered cylinder model was used to simulate 750 sEMG signals with signal-to-noise ratio ranging from -5 to 15 dB (using Gaussian noise) and in each 60-ms signal frame, 1 to 5 IZs were included. The micro- and macro- averaged performance indices were then reported for the proposed IZ detection algorithm. In the micro-averaging procedure, the number of True Positives, False Positives and False Negatives in each frame were summed up to generate cumulative measures. In the macro-averaging, on the other hand, precision and recall were calculated for each frame and their averages are used to determine F1-score. Overall, the micro (macro)-averaged sensitivity, precision and F1-score of the algorithm for IZ channel identification were 82.7% (87.5%), 92.9% (94.0%) and 87.5% (90.6%), respectively. For the correctly identified IZ locations, the average bias error was of 0.02±0.10 IED ratio. Also, the average absolute conduction velocity estimation error was 0.41±0.40 m/s for such frames. The sensitivity analysis including increasing IED and reducing interpolation coefficient for time samples was performed

  14. Contact Analysis of Nominally Flat Surfaces

    DTIC Science & Technology

    2008-06-01

    researchers, Abdo and Farhang [7]. The work began with a literature survey which discussed the work of Greenwood and Williamson and the downfalls of Hertz...Electrical Conductivity γ N or m al iz ed E le ct ric al C on du ct iv ity 1.3 1.4 1.5 1.7 1.9 0.9 1 1.1 1.2 Temperature γ N or m al iz ed T em pe...40 (21 July 2007), pp. 4245-4252. [7] J. Abdo and K. Farhang, “Elastic-Plastic Contact Model for Rough Surfaces Based on Plastic Asperity

  15. Spectrally-Temporally Adapted Spectrally Modulated Spectrally Encoded (SMSE) Waveform Design for Coexistent CR-Based SDR Applications

    DTIC Science & Technology

    2010-03-01

    Faculty Graduate School of Engineering and Management Air Force Institute of Technology Air University Air Education and Training Command in Partial...the time and opportunity to continue my education , and the Laboratory for Telecommunica- tions Sciences for sponsoring this research. Eric C. Like vi...the ktℎ SMSE symbol according to sk[m] = NP−1∑ i=0 N ik−1∑ z=0 di, zk a i m,ku i,z m,kc i,z m,kwme jΘi,z m,k , (3.21) Θi,zm,k = ci,zm,k + di, zk + wm

  16. Identification of Tumor Rejection Antigens for Breast Cancer Using a Mouse Tumor Rejection Model

    DTIC Science & Technology

    2008-05-01

    Days after Tumor Implantation Tu m or S iz e (m m 3 ) 0 10 20 30 40 0 1000 2000 3000 PBS MMC Swap70...or Gsn, or irradiated whole tumor cells at day -42, -28, and -14. Live MMC cells were given subcutaneously on day 0. 0 10 20 30 40...hICD Mtv1 Mtv1 + FxyD3 Mtv1 + FxyD3 + hICD Days after MMC chalange Tu m or s iz e( m m 3) Figure 4. Multi-antigen vaccines

  17. The influence of electromyographic recording methods and the innervation zone on the mean power frequency-torque relationships.

    PubMed

    Herda, Trent J; Zuniga, Jorge M; Ryan, Eric D; Camic, Clayton L; Bergstrom, Haley C; Smith, Doug B; Weir, Joseph P; Cramer, Joel T; Housh, Terry J

    2015-06-01

    This study examined the effects of electromyographic (EMG) recording methods and innervation zone (IZ) on the mean power frequency (MPF)-torque relationships. Nine subjects performed isometric ramp muscle actions of the leg extensors from 5% to 100% of maximal voluntary contraction with an eight channel linear electrode array over the IZ of the vastus lateralis. The slopes were calculated from the log-transformed monopolar and bipolar EMG MPF-torque relationships for each channel and subject and 95% confidence intervals (CI) were constructed around the slopes for each relationship and the composite of the slopes. Twenty-two to 55% of the subjects exhibited 95% CIs that did not include a slope of zero for the monopolar EMG MPF-torque relationships while 25-75% of the subjects exhibited 95% CIs that did not include a slope of zero for the bipolar EMG MPF-torque relationships. The composite of the slopes from the EMG MPF-torque relationships were not significantly different from zero for any method or channel, however, the method and IZ location slightly influenced the number of significant slopes on a subject-by-subject basis. The log-transform model indicated that EMG MPF-torque patterns were nonlinear regardless of recording method or distance from the IZ.

  18. Development of a Fire-Resistant Anti-Sweat Submarine Hull Insulation Based on Fiber Glass Materials.

    DTIC Science & Technology

    1983-09-01

    CHART NATIONAL BUREAU OF STANDARDS-1963-A6w " ;’’ ..J’ d’ ,.,, -,,,.. ,.- -,. . 11111, , .. b,, I - - -.. .,. , .. . ..°.. III. . . ,Lm’ Johns ... Manville Research & Development Center DEVELOPMENT OF A FIRE-RESISTANT ANTI-SWEAT SUBMARINE HULL INSULATION BASED ON FIBER *" GLASS MATERIALS Oct icrb iz Ic

  19. The Shock and Vibration Digest. Volume 8, Number 2, February 1976

    DTIC Science & Technology

    1976-02-01

    procedure and the replace- ment of U/Y by the equivalent Euler oper- ator E(y) results in the extended equations ij = izs.... n. (15) of Galerkin...Geislinger, Leonhard aerodynamic loads to estimate the dynamic MTZ Motortech.3. 36 (2) 51-53 (Feb. 1975) response of the missileduring the blast 2 figs, I ref

  20. Immunization information systems--progress on integration of school nurses: a multi-state roundtable.

    PubMed

    Galemore, Cynthia A

    2011-03-01

    The following is an article and roundtable discussion on school nurse integration into immunization information systems. The discussion participants were April Bailey, Deputy Director, Immunization Division, Indiana State Department of Health; Thomas Maerz, Manager, Wisconsin Immunization Registry; Erin Seward, Immunization Program Manager, Nevada State Health Division; and Debra Warren, Project Manager, KSWebIZ, Kansas Immunization Program.

  1. Information Distribution in Complex Systems to Improve Team Performance

    DTIC Science & Technology

    2006-01-01

    C’ ccf--- _ C’CU M , -- Cý " V D 0E - -2~ 0~ E *:- Z, S~- M2C CD , V - k.C’ 0 C)t ’ -~~~~t M’ Iz-C~C)X ~ ) ) C 0 oo >, ’r 0) CN C) C- 0, Q~ C-4, L L

  2. The role of infarct transmural extent in infarct extension: A computational study.

    PubMed

    Leong, Chin-Neng; Lim, Einly; Andriyana, Andri; Al Abed, Amr; Lovell, Nigel Hamilton; Hayward, Christopher; Hamilton-Craig, Christian; Dokos, Socrates

    2017-02-01

    Infarct extension, a process involving progressive extension of the infarct zone (IZ) into the normally perfused border zone (BZ), leads to continuous degradation of the myocardial function and adverse remodelling. Despite carrying a high risk of mortality, detailed understanding of the mechanisms leading to BZ hypoxia and infarct extension remains unexplored. In the present study, we developed a 3D truncated ellipsoidal left ventricular model incorporating realistic electromechanical properties and fibre orientation to examine the mechanical interaction among the remote, infarct and BZs in the presence of varying infarct transmural extent (TME). Localized highly abnormal systolic fibre stress was observed at the BZ, owing to the simultaneous presence of moderately increased stiffness and fibre strain at this region, caused by the mechanical tethering effect imposed by the overstretched IZ. Our simulations also demonstrated the greatest tethering effect and stress in BZ regions with fibre direction tangential to the BZ-remote zone boundary. This can be explained by the lower stiffness in the cross-fibre direction, which gave rise to a greater stretching of the IZ in this direction. The average fibre strain of the IZ, as well as the maximum stress in the sub-endocardial layer, increased steeply from 10% to 50% infarct TME, and slower thereafter. Based on our stress-strain loop analysis, we found impairment in the myocardial energy efficiency and elevated energy expenditure with increasing infarct TME, which we believe to place the BZ at further risk of hypoxia. Copyright © 2016 John Wiley & Sons, Ltd.

  3. Vibration Experiments

    DTIC Science & Technology

    1963-12-01

    SUSPENSION FORCES = MASS X ACCELERATION Fgz W- VSCZZ + Ni = m (-i + ) ROLL: GUN MOMENT + GROUND FRICTIONAL MOMENT + SUSPENSIONAL MOMENT = ANGULAR...FRICTIONAL MOMENT - SUSPENSIONAL MOMENT = ANGULAR ACCELERATION X MOMENT OF INERTIA - RFaz + !Fgx - (z + z0) FfxCxX - n Nixi = ay~y + Oxix (Ix - Iz) + a2 )i1l

  4. The Functionator 3000: Transforming Numbers and Children

    ERIC Educational Resources Information Center

    Fisher, Elaine Cerrato; Roy, George; Reeves, Charles

    2013-01-01

    Mrs. Fisher's class was learning about arithmetic functions by pretending to operate real-world "function machines" (Reeves 2006). Functions are a unifying mathematics topic, and a great deal of emphasis is placed on understanding them in prekindergarten through grade 12 (Kilpatrick and Izsák 2008). In its Algebra Content Standard, the…

  5. Construction of Optimal-Path Maps for Homogeneous-Cost-Region Path-Planning Problems

    DTIC Science & Technology

    1989-09-01

    209 ’,cond ((null (aref *cell* YtiYn II I IC Kew -cell not explored (setf (acef *ccll* i:z Yr. 1) ;,-’et, and Is not an obstacle, Center-ceXl...School Monterey, CA 93943 2 Dr. Donald R. Barr Valuation Technology, Inc. 6800 Garden Road Monterey, CA 93940 2 Dr. Robert B. McGhee, Code 52Mz

  6. A Simple and Reliable Vacuum Seal for Optical Windows

    DTIC Science & Technology

    1988-01-01

    Journa.1 of Applied Spectroscopy January 1988 Issue COSATI CODES 18. SUBJECT TERMS (Continue on reverse if necessary and identify by block number...1988 M13 -0sfhz i ,.. . APPLIED SPECTROSCOPY 181 1 , .,.trv -,,,-u - . .... ..- ’ ,CELL BODY (F) CELL COY ;%: IZ 6 0 --RING (E) " 0RN E.,L b t

  7. Bi-Layer Wound Dressing System for Combat Casualty Care

    DTIC Science & Technology

    2004-09-01

    diacetate and povidone -iodine cytotoxicity to canine embryonic fibroblast and Staphyloccocus aureus. Vet Surg 17: 182-185. [20] J.F. Fraser, L...C. Bonacorsi, M.S.G. Raddi, and I.Z. Carlos. 2004. Cytotoxicity of chlorhexidine digluconate to murine macrophages and its effect on hydrogen

  8. Cohesion: A New Perspective.

    DTIC Science & Technology

    1983-06-01

    22, 27 July 1982. .I I-Z 130 *1 > ; : . . . . . .. . . .. ... . . . : . .. ; . . . BIBLIOGRAPHY Askenasy , A.R., Perception of Korean Opinions: A...BIBLIOGRAPHY Askenasy , A.R., Perception of Korean Opinions: A Study of U.S. Officer’s Expertise, American University Center for Research in Social

  9. Simultaneous Intracranial EEG-fMRI Shows Inter-Modality Correlation in Time-Resolved Connectivity Within Normal Areas but Not Within Epileptic Regions.

    PubMed

    Ridley, Ben; Wirsich, Jonathan; Bettus, Gaelle; Rodionov, Roman; Murta, Teresa; Chaudhary, Umair; Carmichael, David; Thornton, Rachel; Vulliemoz, Serge; McEvoy, Andrew; Wendling, Fabrice; Bartolomei, Fabrice; Ranjeva, Jean-Philippe; Lemieux, Louis; Guye, Maxime

    2017-02-13

    For the first time in research in humans, we used simultaneous icEEG-fMRI to examine the link between connectivity in haemodynamic signals during the resting-state (rs) and connectivity derived from electrophysiological activity in terms of the inter-modal connectivity correlation (IMCC). We quantified IMCC in nine patients with drug-resistant epilepsy (i) within brain networks in 'healthy' non-involved cortical zones (NIZ) and (ii) within brain networks involved in generating seizures and interictal spikes (IZ1) or solely spikes (IZ2). Functional connectivity (h (2) ) estimates for 10 min of resting-state data were obtained between each pair of electrodes within each clinical zone for both icEEG and fMRI. A sliding window approach allowed us to quantify the variability over time of h (2) (vh (2)) as an indicator of connectivity dynamics. We observe significant positive IMCC for h (2) and vh (2), for multiple bands in the NIZ only, with the strongest effect in the lower icEEG frequencies. Similarly, intra-modal h (2) and vh (2) were found to be differently modified as a function of different epileptic processes: compared to NIZ, [Formula: see text] was higher in IZ1, but lower in IZ2, while [Formula: see text] showed the inverse pattern. This corroborates previous observations of inter-modal connectivity discrepancies in pathological cortices, while providing the first direct invasive and simultaneous comparison in humans. We also studied time-resolved FC variability multimodally for the first time, finding that IZ1 shows both elevated internal [Formula: see text] and less rich dynamical variability, suggesting that its chronic role in epileptogenesis may be linked to greater homogeneity in self-sustaining pathological oscillatory states.

  10. Novel products generated from 2'-deoxyguanosine by hypochlorous acid or a myeloperoxidase-H2O2-Cl- system: identification of diimino-imidazole and amino-imidazolone nucleosides.

    PubMed

    Suzuki, Toshinori; Masuda, Mitsuharu; Friesen, Marlin D; Fenet, Bernard; Ohshima, Hiroshi

    2002-06-01

    Hypochlorous acid (HOCl), generated by myeloperoxidase from H2O2 and Cl-, plays an important role in host defense and inflammatory tissue injury. We report here the identification of products generated from 2'-deoxyguanosine (dGuo) with HOCl. When 1 mM dGuo and 1 mM HOCl were reacted at pH 7.4 and 37 degrees C for 15 min and the reaction was terminated with N-acetylcysteine (N-AcCys), two products were generated in addition to 8-chloro-2'-deoxyguanosine (8-Cl-dGuo). One was identified as an amino-imidazolone nucleoside (dIz), a previously reported product of dGuo with other oxidation systems. The other was identified as a novel diimino-imidazole nucleoside, 2,5-diimino-4-[(2-deoxy-beta-D-erythro-pentofuranosyl)amino]-2H,5H-imidazole (dDiz) by spectrometric measurements. The yields were 1.4% dDiz, 0.6% dIz and 2.4% 8-Cl-dGuo, with 61.5% unreacted dGuo. Precursors of dDiz and dIz containing a chlorine atom were found in the reaction solution in the absence of termination by N-AcCys. dDiz, dIz and 8-Cl-dGuo were also formed from the reaction of dGuo with myeloperoxidase in the presence of H2O2 and Cl- under mildly acidic conditions. These results imply that dDiz and dIz are generated from dGuo via chlorination by electrophilic attack of HOCl and subsequent dechlorination by N-AcCys. These products may play a role in cytotoxic and/or genotoxic effects of HOCl.

  11. Surface Electrical Potentials of Root Cell Plasma Membranes: Implications for Ion Interactions, Rhizotoxicity, and Uptake

    PubMed Central

    Wang, Yi-Min; Kinraide, Thomas B.; Wang, Peng; Hao, Xiu-Zhen; Zhou, Dong-Mei

    2014-01-01

    Many crop plants are exposed to heavy metals and other metals that may intoxicate the crop plants themselves or consumers of the plants. The rhizotoxicity of heavy metals is influenced strongly by the root cell plasma membrane (PM) surface’s electrical potential (ψ0). The usually negative ψ0 is created by negatively charged constituents of the PM. Cations in the rooting medium are attracted to the PM surface and anions are repelled. Addition of ameliorating cations (e.g., Ca2+ and Mg2+) to the rooting medium reduces the effectiveness of cationic toxicants (e.g., Cu2+ and Pb2+) and increases the effectiveness of anionic toxicants (e.g., SeO42− and H2AsO4−). Root growth responses to ions are better correlated with ion activities at PM surfaces ({IZ}0) than with activities in the bulk-phase medium ({IZ}b) (IZ denotes an ion with charge Z). Therefore, electrostatic effects play a role in heavy metal toxicity that may exceed the role of site-specific competition between toxicants and ameliorants. Furthermore, ψ0 controls the transport of ions across the PM by influencing both {IZ}0 and the electrical potential difference across the PM from the outer surface to the inner surface (Em,surf). Em,surf is a component of the driving force for ion fluxes across the PM and controls ion-channel voltage gating. Incorporation of {IZ}0 and Em,surf into quantitative models for root metal toxicity and uptake improves risk assessments of toxic metals in the environment. These risk assessments will improve further with future research on the application of electrostatic theory to heavy metal phytotoxicity in natural soils and aquatic environments. PMID:25493475

  12. A novel facile synthesis and characterization of molybdenum nanowires

    PubMed Central

    2012-01-01

    We describe a straightforward technique to synthesize pure Mo nanowires (NWs) from Mo6SyIz (8,2 Iz NWs are annealed in Ar/H2 mixture leading to the formation of pure Mo NWs with similar structures as initial morphologies. Detailed microscopic characterizations show that large diameters (>15 nm) Mo NWs are highly porous, while small diameters (<7 nm) are made of solid nanocrystalline grains. We find NW of diameter 4 nm can carry up to 30 μA current without suffering structural degradation. Moreover, NWs can be elastically deformed over several cycles without signs of plastic deformation. PMID:23061810

  13. Reducing the duration of broadband excitation pulses using optimal control with limited RF amplitude.

    PubMed

    Skinner, Thomas E; Reiss, Timo O; Luy, Burkhard; Khaneja, Navin; Glaser, Steffen J

    2004-03-01

    Combining optimal control theory with a new RF limiting step produces pulses with significantly reduced duration and improved performance for a given maximum RF amplitude compared to previous broadband excitation by optimized pulses (BEBOP). The resulting pulses tolerate variations in RF homogeneity relevant for standard high-resolution NMR probes. Design criteria were transformation of Iz-->Ix over resonance offsets of +/-20kHz and RF variability of +/-5%, with a pulse length of 500 micros and peak RF amplitude equal to 17.5 kHz. Simulations transform Iz to greater than 0.995 Ix, with phase deviations of the final magnetization less than 2 degrees, over ranges of resonance offset and RF variability that exceed the design targets. Experimental performance of the pulse is in excellent agreement with the simulations. Performance tradeoffs for yet shorter pulses or pulses with decreased digitization are also investigated.

  14. Sampling and composition of airborne particulate matter (PM10) from two locations of Mexico City.

    PubMed

    Chirino, Yolanda I; Sánchez-Pérez, Yesennia; Osornio-Vargas, Álvaro Román; Rosas, Irma; García-Cuellar, Claudia María

    2015-09-01

    The PM10 airborne particulate matter with an aerodynamic diameter ≤10 µm is considered as a risk factor of various adverse health outcomes, including lung cancer. Here we described the sampling and composition of PM10 collected from an industrial zone (IZ), and a commercial zone (CZ) of Mexico City. The PM10 was collected with a high-volume sampler in the above mentioned locations and both types of PM10 sampled were characterized by the content of polycyclic aromatic hydrocarbons (PAHs), metals, and endotoxin. The endotoxin PM10 content from IZ and CZ displayed 138.4 UE/mg and 170.4 UE/mg of PM10, respectively.

  15. VizieR Online Data Catalog: Stellar population in Chamaeleon I (Luhman, 2007)

    NASA Astrophysics Data System (ADS)

    Luhman, K. L.

    2009-05-01

    Optical and near-IR broadband photometry from several sources (2MASS and DENIS for IK1 & IK2) were used to perform four surveys (IK1, RI, IK2, IZ). For RI, on the night of 2004 January 11, R- and I-band images obtained with the Inamori Magellan Areal Camera and Spectrograph (IMACS) on the Magellan I telescope at Las Campanas Observatory were used. Deep optical and near-IR images of the densest portion of the southern subcluster that were obtained by Luhman et al. (2005ApJ...635L..93L,) collected with the Advanced Camera for Surveys (ACS) aboard HST through the F775W and F850LP filters were used for IZ. (6 data files).

  16. Reducing the duality gap in partially convex programming

    SciTech Connect

    Correa, R.

    1994-12-31

    We consider the non-linear minimization program {alpha} = min{sub z{element_of}D, x{element_of}C}{l_brace}f{sub 0}(z, x) : f{sub i}(z, x) {<=} 0, i {element_of} {l_brace}1, ..., m{r_brace}{r_brace} where f{sub i}(z, {center_dot}) are convex functions, C is convex and D is compact. Following Ben-Tal, Eiger and Gershowitz we prove the existence of a partial dual program whose optimum is arbitrarily close to {alpha}. The idea, corresponds to the branching principle in Branch and Bound methods. We describe such a kind of algorithm for obtaining the desired partial dual.

  17. Comparison of the Centers for Disease Control and Prevention-backpack and insectazooka aspirators for sampling Aedes polynesiensis in French Polynesia.

    PubMed

    Hapairai, Limb K; Sang, Michel A Cheong; Bossin, Hervé C

    2014-06-01

    The efficiency of the recently developed handheld InsectaZooka (IZ) aspirator was compared to that of the Centers for Disease Control and Prevention-Backpack (CDC-BP) aspirator by conducting human bait collections on 2 islets (locally called motus) of the atoll of Tetiaroa, French Polynesia. Abundance of mosquitoes was compared between the wind-exposed and wind-protected sides of each motu to measure the effect of wind on mosquito distribution. The number of host-seeking Aedes polynesiensis mosquitoes collected on the 2 motus with either sampling device was not significantly different. Collection of male mosquitoes was low irrespective of the type of aspirator used. Wind had an effect on mosquito distribution, as females were more abundant on the protected sides of both motus. The IZ aspirator is a lighter and equally efficient alternative to the CDC-BP aspirator for collecting Ae. polynesiensis.

  18. Singular Instantons and Painlevé VI

    NASA Astrophysics Data System (ADS)

    Muñiz Manasliski, Richard

    2016-06-01

    We consider a two parameter family of instantons, which is studied in [Sadun L., Comm. Math. Phys. 163 (1994), 257-291], invariant under the irreducible action of SU_2 on S^4, but which are not globally defined. We will see that these instantons produce solutions to a one parameter family of Painlevé VI equations (P_VI}) and we will give an explicit expression of the map between instantons and solutions to P_{VI}. The solutions are algebraic only for that values of the parameters which correspond to the instantons that can be extended to all of S^4. This work is a generalization of [Muñiz Manasliski R., Contemp. Math., Vol. 434, Amer. Math. Soc., Providence, RI, 2007, 215-222] and [Muñiz Manasliski R., J. Geom. Phys. 59 (2009), 1036-1047, arXiv:1602.07221], where instantons without singularities are studied.

  19. Flame Stabilization and Structure of Reaction Zones

    DTIC Science & Technology

    2009-03-31

    observed in many experiments (Muñiz and Mungal, 1997, Brown et al., 1999, Lee et al., 1997, Kalghatgi, 1984). Results of cinema -PIV (particle image...data. Upatnieks et al. (2004) used cinema -PIV to study turbulent flames and found that the propagation of the flame base was close to the laminar... Philosophy . California Institute of Technology, Pasadena, CA., 1-140. Hammer, J.A. and Roshko, A. (2000) Temporal behavior of lifted turbulent jet flames

  20. Numerical Analysis of Laminated, Orthotropic Composite Structures

    DTIC Science & Technology

    1975-11-01

    F0R«AT(128H0 TEMPERATURE EPSP EPSZ EPSC IZ EPSZC FPSCP EPSN EPSS E»ST EPSNS 2 E«>STM) 2003 F0RHA’(6X,F13.0,2X,12F«».5) PETtlPN END...SIGMAP SIGMAZ SIGMAC SIGMA SIGMAS S!GMAT SIGMANS SIOMAST EPSP EPSST LnCATTrN 0 2« LXA^ICN 0 LOCATION 0 IC20 COPMOK BLOCK /BASIC

  1. Navy Recruitment Potential in Junior Colleges

    DTIC Science & Technology

    1975-07-01

    could be employed in recruitment advertising directed to this target market segment. ~~iZ Uncla ssifie d SECURITY CLAUIPIC~f(ATION OFf THIS PA09(Wh•l...Alexandria, Virginia, CR-ED-74-1, July 1974. Grey Advertising . Market Target Recruitmen~t Incentive Study for Enlisted Personnel (draft report, internal NRC...the recruiter or the various advertising media. Survey findings document the importance of the recruiter, and suggestpromising media and appeals which

  2. Analytical and Experimental Studies of Beam Waveguide Absorbers for Structural Damping.

    DTIC Science & Technology

    1988-03-01

    la\\cr %~ilwVadc aoorbcr rthle 1 )U NUC-IzN irqtenva2e. Allt constant Variabls of’ tile Redu,-e rog-ram1 were defined inl eachi FORTRAN-k, program. We...thle infinite beaml as i’rcq uenc(: inl - creaIse. Thle results of’ thle Bernoul-1E1-uler beam theory do riot quite corres;pond to ex- perrirntl suls...2... ............ ... .... ... . .. .. . . .. ... lmr

  3. The Soviet Airborne Experience

    DTIC Science & Technology

    1984-11-01

    nastupatel’naya operatsiya” [Army offensive operations], SVE, 1:239-44; N. Kireev , “Pr imenenie tankovykh podraelenii i chas tei pr i proryve oborony...forward detachments would be of reinforced tank regiment size; division forward detachments of reinforced tank battalion size. See Kireev ...Primenenie,” 38-39. For the origins of,,;he concept and cur,fent applicability, see N. Kireev N. Dovbenko, Iz oivta boevogo primeneniya peredovykh

  4. A Nomogram for Calculation of Oxygen Consumption from Minute Ventilation at Varying Workloads

    DTIC Science & Technology

    1979-07-01

    981~ IZ:;: I~ ~ TATL’MLNrh j.V Approved for public releasel ’ý [ I .Ad& - ABSTRACT .L Oxygen consumption can be difficult and time consuming to measure ...employed to evaluate diff-erent aspects of cardiopulmonary function (1). One of the principal measurements used to quantify response to exercise is...the oxygen consumption. The direct measurement of oxygen consumption is time consuming and cumbersome. Unfortunately, no reliable indirect method for

  5. Nonmetallic Inclusions in HSLA Steel Weldments

    DTIC Science & Technology

    1989-12-01

    lowering the DBTT . Nickel prevents the hot shortness phenomenon often observed in copper-bearing steels . Nickel is also an austenite stabilizer. By lowering... STEEL WELDMENTS by Brent A. Douglas December, 1989 Thesis Advisor Alan G. Fox Approved for public release; distribution is unlimited. 90 ,-. S...ACCESSION NO. II. TITLE (Incude Security Claw fication) Nonmetallic Inclusions In HSLA Steel Weldments IZ. PERSONAL AUTHOR(S) Douglas, Brent A. 138

  6. Commercial Aircraft Noise Definition - L1011 Tristar. Volume 1

    DTIC Science & Technology

    1974-09-01

    eat tao twaice dwtatiozws betueen the In db dwna pulntt of t$* tosvai~ rv pereied noise Ivu tit* histars e ah*~n cnii~ta~ n~ 4kcrojtonc,- %vivenr~ie a...apu ~t zmf tltittsk. tz vaw rozten *, plin 4ov-, trsv .*Lgai* ie P04Sed to �w AOý- prtht rOutt tar %=e izý4 clcttatlre tiate alaft’ the f~lwe.t jatt

  7. U.S. Coast Guard Officer Performance Management System: An Analysis of Current Commitment Levels and Potential Effectiveness Indicators.

    DTIC Science & Technology

    1983-03-01

    service cites several perceptions which will impact on gene:al systeis effectiveness of any perfromance appraisal efforts directed at the coast Guard...OF CUR’RENT COMMITMENT LEVELS AND POTENTIAL EFFECTIVENESS INrICATORS by Patrick J. Popieski March 1983 Thesis Advisor: R.A. Weitzman Approved for...34widec Commitment Lqvels and Potential Effectiveress 441. AUYWO11141) ILl1ar . CONTOACT on GoA~tifIz 1R. Patrick James Popieski -9. PERFOMING OftANIZAI

  8. High Energy Halogen Chemistry.

    DTIC Science & Technology

    1978-01-01

    diphenylsilanes , displacement of halo- gen to give the nitro compound, oxidative nitration and fluorination to give — the fluorodinitro compound, and...V - - - - Simple oxetanes arc gen ~rally obtained by cycl iz ing :~onotosy lates of 1,3-diols with...d initro - tropropy lltr imethyls ilane . using the theor etica l amount of and fluorodinitrosi lanes and polysiloxanes by the step wise base, gave

  9. Technical and Operational Evaluation of USCGC DORADO (WSES-1).

    DTIC Science & Technology

    1982-08-01

    safely? Not observed Yes No 15. If no, what are the main prcblem areas? 116. co you thirk it is safe to put a swimmer in the water from this vessel...ize 1270 Toob i: I=1I* 10 1280 LimnLim/10 1i290 G* OT0 C hecr.k iz=e 1300 Dn e: IF IMT (Liur0< >Lirn THEM 32 IF Signɘ THEM Lirfa=Lirti+I*Sign, 133

  10. Gordon Research Conference on Dynamics of Macromolecular and Polyelectrolyte Solutions Held in Oxnard, California on 12-16 February 1990

    DTIC Science & Technology

    1990-04-01

    Polyelectrolyte Solutions* was held IZ-16 February, 1990, at Casa Sirena Hotel, Oxnard, CA There were ninety-one scientists iarticipatIng. ’cludiq thirty-four...MACROMOLECULAR AND POLYELECT’ROLYTE 5’LUToNS Casa Sirena . Oxnard. CA Lee Magid - Chairman Peter Pusey - VIce-Chairman Monday. February 12 S.J. Candau...12-16, 1990 Casa Sirena Marina Hotel Oxnard, California REGISTRATION LIST Bruce J. Ackerson 149 Sauver Candau 136 Oklahoma State University Universit4

  11. Letters

    NASA Astrophysics Data System (ADS)

    1999-01-01

    A Coordination Geometry Table by Francisco J. Arnáiz Re: article by D. Venkataraman, Y. Du, S. R. Wilson, K. A. Hirsch, P. Zhang, and J. S. Moore The authors reply Cut-Out Molecular Models by A. L. Silva, C. Fernandes, O. Wasterlain, S. Costa, and A. M. Mendes Re: article by R. J. Kashmar Kinetics Lesson for College Deans by Fred Hadley

  12. Vibrational Relaxation of DF (v = 1-4) in D2, H2, N2, HF, and CO2

    DTIC Science & Technology

    1980-01-15

    ft let t C nnfo b*1 --GPM)!I I ii, KEY tOROS (Cnsbw ren Pee# Vi04 itncy end ifdlfr ~IZ Y bleeP ntbm) Ch,!micp~l Lazier Vibrational Deactivation -j...rates of the test gases were measured with rotating bal flowmeters calibrated by pressure-rise measuremets in a standard volume. The DF flow was regulated

  13. Tracking in Uncertain Environments

    DTIC Science & Technology

    1989-09-01

    information should be used for trajectory estimation. A filter which refines past estimates in the light of subsequent measurements is called a smoothing ...filter. In terms of the pdf of target state, for a smoothing filter we require: P(x-IZ1, *. Zn) where k < n . For standard filtering problems without...measurement uncertainty, efficient optimal smoothing algorithms have been derived (see Jazwinski 27). For trajectory estimation, it has been shown that

  14. Some Topics in Linear Estimation,

    DTIC Science & Technology

    1981-01-01

    outstanding symposium. Iz SOME TOPICS IN LINEAR ESTIMATION 309 TABILE OF CONTENTS 1. The Integral Equations of Smoothing and Filtering la. The Smoothing ... Smoothing and Filtering 2. Some Examples - Stationary Processes 2a. Scalar Stationary Processes over Infinite Intervals 2b. Finite Intervals - The...Stationary 4. A Concluding Remark 310 T. KAILATH 1. The Integral Equations of Smoothing and Filtering Our estimation problems will be discussed in the context

  15. An Analysis of Healthcare Provider Productivity in Selected Clinical Services at Moncrief Army Community Hospital

    DTIC Science & Technology

    1990-08-13

    basis of this study. Serway (1987) suggests several productivity indicators to include: 1. FTEs per adjusted occupied bed. 2. Total operating expense...392). Note that Serway relies heavily on the kind of dollar oriented measures of output that are discouraged by Reiling, Owens, Choich, Ford and...IzComparisons for Physicians and Nurse Practitioners. Medical Care. 20(2), 143-153.z Serway , G., Strum, D., & Haug, W. (1987). Alternative Indicators for

  16. Improving the Value Engineering Change Proposal Process within the U.S. Army Corps of Engineers

    DTIC Science & Technology

    1993-08-01

    his staff engineers, Lawrence Miles, to investigate the feasibility of substituting one product for another in order to increase efficiency. Miles...TO UEV!tL ARW TEM 2 rT AXL 447 -- X50~S 3. D=Iz the next few mzithe, our , qmrters will pibiisi guLc~m iff lesscwo Leavied to further ct d=eStenUmu

  17. Operational Principles. The Operational Art of Erwin Rommel and Bernard Montgomery

    DTIC Science & Technology

    1985-01-01

    7 OPERATIONAL PRINCIPLES: THE OPERATIONAL ART OF ERWIN ROMMEL AND BERNARD MONTGOMERY A thesis presented to the Faculty of the US Army Command and...h- rfrC -= S Leaven,pwnrth. iz0 27. - 85-3214 141 OPERATIONAL PRINCIPLES: THE OPERATIONAL ART OF ERWIN ROMMEL AND BERNARD MONTGOMERY A thesis...Principles: The Operational Art of Erwin Rommel and Bernard Montgomery. Approved by: esis Committee ChairmanTCD lsV2onson, MA) , _ __, Member, Graduate Faculty

  18. Letters

    NASA Astrophysics Data System (ADS)

    1998-12-01

    Beer's Law: The Real Hazards by S. R. Logan Re: article by M. A. Muyskens and E. T. Sevy The author replies Photodimerization of Maleic Anhydride by Zhijun Zhang Re: article by D. Todd and M. Pickering (J. Chem. Educ. 1988, 65, 1100) Qual from a Different Viewpoint by Francisco J. Arnáiz Re: article by M. Laing (J. Chem. Educ. 1993, 70, 666)

  19. Modeling a 300 kHz Bathymetric Sonar System

    DTIC Science & Technology

    1992-09-01

    AD-A257 378 /7 Modeling A 300 kHz Bathymetric Sonar System by Kenneth Alan Malmquist B.S., Drexel University, Philadelphia (1985) Submitted in...Massachusetts Institute of Technology/ Woods Hole Oceanographic Institution 92-28033 Vll1 Nlf • 92 BLANK PAR Modeling A 300 kIz Bathymetric Sonar System by...Deep Submergence Laboratory has developed a family of calibrated high frequency bathymetric sonar systems for underwater survey. It is useful to have a

  20. Archaeological Investigations in the Gainesville Lake Area of the Tennessee-Tombigbee Waterway. Volume V. Archaeology of the Gainesville Lake Area: Synthesis.

    DTIC Science & Technology

    1982-09-01

    237 15. Sumary of Plant Food Remains from Miller III and Summerville I Features .. ......... . ........... 248 Iz zi j...Director of The University of Alabama, Office of Archaeological Research (OAR), believed that this project could be finish- ed and he perservered to see...economies based upon a few high-yield natural foods , and the earliest cultivation of native annuals. This final period in the Archaic sequence dates

  1. Chatanika Radar Measurements during the Auroral E Program

    DTIC Science & Technology

    1981-06-01

    region neutral winds have biased the elevation scan measurements. 16 0 WIAW -- 3 * I I I 0 -r I co I Iz aa ’I 0 Ii z J-4 * I i I0 0 w -J w4j w Cc 0 ~I U...V. Starkov , "Dynamics of Auroral Belt and Polar Geomagnetic Disturbances," Planet. Sp. Sci., 15, 209-229 (1967). Gussenhoven, M. S., D. A. Hardy

  2. VizieR Online Data Catalog: Photometric brown-dwarf classification (Skrzypek+, 2016)

    NASA Astrophysics Data System (ADS)

    Skrzypek, N.; Warren, S. J.; Faherty, J. K.

    2016-02-01

    Table 3 (L dwarfs) and Table 4 (T dwarfs) provide coordinates and photometry of the 1281 L dwarfs and 80 T dwarfs, J<17.5, found by Skrzypek et al. 2016 using the photo-type classification method. Coordinates and photometry in izYJHKW1W2 (on the Vega system) is provided, as well as the photo-type classification, and any existing spectroscopic classification in the literature. (3 data files).

  3. The Climate in the Region of Djerdap (The Iron Gate),

    DTIC Science & Technology

    1982-01-21

    this report. LITERATURE (1) Milosavljevi, K. und M.: Uticaj orografije na raspodeu pad ina u ZuWto- noj Srbij. Zbornzk radova Poljoprivrednog fakuiteta...i-i, (ion). (2) MilosavleviO K. und M.: Raspodela padavina u Isto~noj Srbiji pri vero- vima iz severozapadnog kvadranta. Zbornik meteoroakTh i...hidro1ikIh radova br. 1. Savezm hidrometeorolo~ki zavod, Bpograd, 1-9, (1963). 3. K. Milosavljevic, M. Milosavljevic. Effect of the Transylvanian Alps on

  4. A Historical Analysis of Basic Air Force Doctrine Education within the United States States Air Force Air Command and Staff College, 1947-1987.

    DTIC Science & Technology

    1987-09-01

    Doctrinal Education. 2. dow tne uality of Air University Students Influences Doctrinal Educaion . 3. iow Air iniversity Commanders Have Influenced...AIin i.i .Iz: 0o 1 Lac, ani AFB, T>xas. Aft-2r Zmfl5Oli i , Janiu~rv .18;, -ie itce nu,_i_ Trdnsoorctation Otf iLzer scnooL at 31,,. pa r J A :a, ras

  5. Water Vapor as a Tracer in Remote Wind Sensing: A Feasibility Study.

    DTIC Science & Technology

    1982-08-01

    BY 04 1. L. Barber DTIC K ELECT E Approved for public release; distribution unlimited. C" D US Army Electronics Research and Development Command...14 D ATA ANALYSIS ........................................... . .......... 18 ""CONCL USI ONS...1T’TS GRA&I ,xc TAB U 13- :,-iounce d lii .j.-t, ifiat io -:.i 𔃼bility Codes Avnii and/or r~ir t pecialK IZ Le p.3 INTRODUCTION The military is becoming

  6. Myungshin Im, Won-Kee Park, Changsu Choi, Yiseul Jeon, Ji-Hoon Kim (CEOU/SNU), Giseon Baek, Young-Seok Oh, Soojong Pak (Kyunghee Univ.)

    NASA Astrophysics Data System (ADS)

    Im, Myungshin; Park, Won-Kee; Choi, Changsu; Jeon, Yiseul; Kim, Ji-Hoon; Baek, Giseon; Oh, Young-Seok; Pak, Soojong

    2011-08-01

    On August 30 02:05 UT, we started observations of SN2011fe=PTF11kly (ATel#3581) in grizY and is/iz-bands using CQUEAN on the 2.1m telescope at McDonald observatory, and in zYJHK-bands using UKIRT. SN2011fe is found to have J~11.58 and K~11.55 mag (error~0.05 mag), still brightening in NIR with respect to ATel#3605.

  7. Meeting the Combat Stress Challenge: Special Psychological Intervention and Reintegration Teams (SPIRITs)

    DTIC Science & Technology

    1988-04-01

    S~AIR COMMAND AND STAFF COLLEGE STUDENT REPORT MEETING THE COMBAT STRESS CHALLENGE: SPECIAL PSYCHOLOGICAL INTERVENTION AND REINTEGRATION TEAMS...INTERVENTION AND REINTEGRATION TEAMS (SPIRITs) AUTHOR(S) MAJOR DAVID L. HERRES, USAF, BSC FACULTY ADVISOR CHAPLAIN, LT COL, DAVID W. FAHNER, USAF, ACSC/IHC...AND REINTEGRATION TEAMS (SPIRITs) IZ. PERSONAL AUTHOR(S) HERRES, DAVID L., MAJOR, USAF, BSC 13a. TYPE OF REPORT 13b.’TIME COVERED 14. DATE OF REPORT

  8. Nitrate-nitrogen, land use/land cover, and soil drainage associations at multiple spatial scales.

    PubMed

    Floyd, William C; Schoenholtz, Stephen H; Griffith, Stephen M; Wigington, Parker J; Steiner, Jeffrey J

    2009-01-01

    Managing non-point-source pollution of water requires knowledge of land use/land cover (LULC) influences at altering watershed scales. To gain improved understanding of relationships among LULC, soil drainage, and dissolved nitrate-N dynamics within the Calapooia River Basin in western Oregon, we selected 44 watersheds ranging in size between 3 and 33 km(2) for monthly synoptic sampling of surface water quality between October 2003 and September 2004. Seasonal associations were examined between dissolved nitrate-N and proportion of woody vegetation or poorly drained soils at differing scales (10, 20, 30, 60, 90, 150, 300 m, and entire watershed), which we defined as influence zones (IZs), surrounding stream networks. Correlations between nitrate-N and proportion woody vegetation or poorly drained soil at each IZ were analyzed for differences using the Hotelling-Williams test. We observed negative correlations (r = -0.81 to -0.94) between nitrate-N and proportion of woody vegetation during winter and spring. Poorly drained soils had positive correlations (r = 0.63-0.87) with nitrate-N. Altering the scale of analysis significantly changed correlations between nitrate-N and woody vegetation, with IZs <150 m being stronger than the watershed scale during winter. However, absolute differences in correlation values were small, indicating minimal ecological consequence for significant differences among scales. In contrast, nitrate-N correlations with poorly drained soil were stronger at the watershed scale than the 10- through 90-m IZs during winter and spring, and absolute differences were sufficient to suggest that scale is ecologically important when determining associations between dissolved nitrate-N and poorly drained soils.

  9. Origin and Subsequent Modifications of Explosive Safety Quantity- Distance (ESQD) Standards for Mass Detonating Explosives with Special Reference to Naval Vessels. Volume 2. Appendices

    DTIC Science & Technology

    1978-05-01

    appear at the end of each appendix in order not to disrupt text continuity) stmarizes the volumes investigated of the DDESB’S "Minutes of Meetings...topic of report. j L 12 - * - Table A-2. Highlights from Suzlnary Notes of B.L. Knasel, DDESB* Rough draft dated 15 March 1976 (this material is in front ...being done on various draft versions, if iz was included in a year- end sumary submitted to the Deputy, Assistant Secretary of Defense (Installationz and

  10. Early Detection of Breast Cancer Using Posttranslationally Modified Biomarkers

    DTIC Science & Technology

    2013-09-01

    SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON USAMRMC a. REPORT U b . ABSTRACT U... B CP-GSH No rm al iz ed Fl uo re sc en ce In te ns ity Be nig n Inv as ive C an ce r 0.5 1 2...between studies. A .CP- GSH, glutathionylated ceruloplasmin; B . PDGF-4HNE, 4-hydroxynonenal-adducted platelet-derived growth factor. Each data point

  11. Towards an informative mutant phenotype for every bacterial gene

    SciTech Connect

    Deutschbauer, Adam; Price, Morgan N.; Wetmore, Kelly M.; Tarjan, Daniel R.; Xu, Zhuchen; Shao, Wenjen; Leon, Dacia; Arkin, Adam P.; Skerker, Jeffrey M.

    2014-08-11

    Mutant phenotypes provide strong clues to the functions of the underlying genes and could allow annotation of the millions of sequenced yet uncharacterized bacterial genes. However, it is not known how many genes have a phenotype under laboratory conditions, how many phenotypes are biologically interpretable for predicting gene function, and what experimental conditions are optimal to maximize the number of genes with a phenotype. To address these issues, we measured the mutant fitness of 1,586 genes of the ethanol-producing bacterium Zymomonas mobilis ZM4 across 492 diverse experiments and found statistically significant phenotypes for 89% of all assayed genes. Thus, in <i>Z. mobilis, most genes have a functional consequence under laboratory conditions. We demonstrate that 41% of <i>Z. mobilis genes have both a strong phenotype and a similar fitness pattern (cofitness) to another gene, and are therefore good candidates for functional annotation using mutant fitness. Among 502 poorly characterized <i>Z. mobilis genes, we identified a significant cofitness relationship for 174. For 57 of these genes without a specific functional annotation, we found additional evidence to support the biological significance of these gene-gene associations, and in 33 instances, we were able to predict specific physiological or biochemical roles for the poorly characterized genes. Last, we identified a set of 79 diverse mutant fitness experiments in <i>Z. mobilis that are nearly as biologically informative as the entire set of 492 experiments. Therefore, our work provides a blueprint for the functional annotation of diverse bacteria using mutant fitness.

  12. National Program for Inspection of Non-Federal Dams. Lake Madeleine (VT 00007) Hudson River Basin, Sandgate. Phase I Inspection Report.

    DTIC Science & Technology

    1978-09-01

    PROJECT FEATURE NAME M. R. Peloso DISCIPLINE NAME AREA EVALUATED CONDITION OUTLET WORKS - CONTROL TOWER a. Concrete and Structural General Condition...ELEMENT PROJECT, TASK AREA 4 WORK UNIT NUMBERS 11. CONTROLLING OFFICE NAME AND ADDRELSS IZ. RSPORT DATE DEPT. OF THE ARMY: CORPS OF ENGINEERS September... Works There are three outlets from Lake Madeleine. They are: the penst ock, the overflow pipe and the emergency spill- way. The primary outlet used for

  13. Time-Dependent Environmental Behavior of Graphite/Epoxy Composites

    DTIC Science & Technology

    1980-05-01

    moisture con- tent at two different humidities) conditions. Coupons for dry tests were initally desiccated for several days at moderately Pievated...tned to use 464 0 K (375 0 F) as our highest dry test temperature. After conducting some early testing at that temperature and experiencing various...li1ieI Iz j For dry tests , an oven was placed about the fixture, with a tray of desiccant, and the temperature was continuousivy ,oni- tored by a

  14. Archaeological Investigations at Site 45-DO-211, Chief Joseph Dam Project, Washington.

    DTIC Science & Technology

    1984-01-01

    tool manufacturing techniques. Journal of Field Archaeology 2:125-131. Franklin, J.F., and C.T. Dyrness 1973 Natural vegetation of Oregon and Washington...Figure 3-2. Edge angle distributions of tools classified as wear only and wear and manufacture .... ................. .... 70 Figure 3-3. Definition of...modified rocks, and 71 nonlithic and historic artifacts was recovered. The lithic assemblage Includes 386 worn and/or manufactured tools . REPORT ORGM IZ

  15. DARPA - Advanced Composite Materials Annual Presentation Held in Gainesville, Florida on 19-20 November 1992

    DTIC Science & Technology

    1992-11-20

    12:00-1:30 Lunch 1:30 Informal Subgroup Discussions and Tour of the Facilities .... APPROVED FD?, P’ ,TLIC PELEAS - "’ DISIRiBuTO.. U Li,6raD Avail...110Iz TEMPERATURE (°C) I r I A 0.Ig .I ... I--A Ile II IT 0. I. I I I I. S102 - AV ) 3 PHASE DIAGRAM 2020 UMOLE % A12%3 0 020 40 Go o 100 2000. ML_

  16. Effect of the microstructure on the lifetime of dental ceramics

    PubMed Central

    Borba, Márcia; de Araújo, Maico D.; Fukushima, Karen A.; Yoshimura, Humberto N.; Cesar, Paulo F.; Griggs, Jason A.; Della Bona, Álvaro

    2011-01-01

    Objectives To evaluate the effect of the microstructure on the Weibull and slow crack growth (SCG) parameters and on the lifetime of three ceramics used as framework materials for fixed partial dentures (FPDs) (YZ - Vita In-Ceram YZ; IZ - Vita In-Ceram Zirconia; AL - Vita In-Ceram AL) and of two veneering porcelains (VM7 and VM9). Methods Bar-shaped specimens were fabricated according to the manufacturer’s instructions. Specimens were tested in three-point flexure in 37°C artificial saliva. Weibull analysis (n=30) and a constant stress-rate test (n=10) were used to determine the Weibull modulus (m) and SCG coefficient (n), respectively. Microstructural and fractographic analyses were performed using SEM. ANOVA and Tukey’s test (α=0.05) were used to statistically analyze data obtained with both microstructural and fractographic analyses. Results YZ and AL presented high crystalline content and low porosity (0.1–0.2%). YZ had the highest characteristic strength (σ0) value (911 MPa) followed by AL (488 MPa) and IZ (423 MPa). Lower σ0 values were observed for the porcelains (68–75 MPa). Except for IZ and VM7, m values were similar among the ceramic materials. Higher n values were found for YZ (76) and AL (72), followed by IZ (54) and the veneering materials (36–44). Lifetime predictions showed that YZ was the material with the best mechanical performance. The size of the critical flaw was similar among the framework materials (34–48 µm) and among the porcelains (75–86 µm). Significance The microstructure influenced the mechanical and SCG behavior of the studied materials and, consequently, the lifetime predictions. PMID:21536324

  17. A Plasma Ultraviolet Source for Short Wavelength Lasers.

    DTIC Science & Technology

    1986-03-10

    Magnetoplasma Compressions", G. N . Kashnikov, V. K. Orlov, A. N . Panin, A. K. Piskunov and V. A. Reznikov, Sov. J. Quantum Electron. 10, 1193 (1983...i...i -..,:- . m.:...,o -,., .. .._._ _, ., -._ _-> .... ,:: , --.,..-, .: - -- r -’ - N q- I. I T .1 - 7 --- r...DOCUMENTATIONPAGE_ BEFORE COMPLETING FORM I. REPORT NUMBER 2. GOVT ACCESSION NO. 3. RECIPIENT’S CATALOG NUMBER AP.-OS7’a I IZ. G ASN/A N /A 4. TITLE (and Subtitle

  18. THE GALACTIC O-STAR SPECTROSCOPIC SURVEY. I. CLASSIFICATION SYSTEM AND BRIGHT NORTHERN STARS IN THE BLUE-VIOLET AT R {approx} 2500

    SciTech Connect

    Sota, A.; Maiz Apellaniz, J.; Alfaro, E. J.; Barba, R. H.; Morrell, N. I.; Gamen, R. C.

    2011-04-01

    We present the first installment of a massive spectroscopic survey of Galactic O stars, based on new, high signal-to-noise ratio, R {approx} 2500 digital observations from both hemispheres selected from the Galactic O-Star Catalog of MaIz Apellaniz et al. and Sota et al. The spectral classification system is rediscussed and a new atlas is presented, which supersedes previous versions. Extensive sequences of exceptional objects are given, including types Ofc, ON/OC, Onfp, Of?p, Oe, and double-lined spectroscopic binaries. The remaining normal spectra bring this first sample to 184 stars, which is close to complete to B = 8 and north of {delta} = -20{sup 0} and includes all of the northern objects in MaIz Apellaniz et al. that are still classified as O stars. The systematic and random accuracies of these classifications are substantially higher than previously attainable, because of the quality, quantity, and homogeneity of the data and analysis procedures. These results will enhance subsequent investigations in Galactic astronomy and stellar astrophysics. In the future, we will publish the rest of the survey, beginning with a second paper that will include most of the southern stars in MaIz Apellaniz et al.

  19. Ascl1 promotes tangential migration and confines migratory routes by induction of Ephb2 in the telencephalon

    PubMed Central

    Liu, Yuan-Hsuan; Tsai, Jin-Wu; Chen, Jia-Long; Yang, Wan-Shan; Chang, Pei-Ching; Cheng, Pei-Lin; Turner, David L.; Yanagawa, Yuchio; Wang, Tsu-Wei; Yu, Jenn-Yah

    2017-01-01

    During development, cortical interneurons generated from the ventral telencephalon migrate tangentially into the dorsal telencephalon. Although Achaete-scute family bHLH transcription factor 1 (Ascl1) plays important roles in the developing telencephalon, whether Ascl1 regulates tangential migration remains unclear. Here, we found that Ascl1 promoted tangential migration along the ventricular zone/subventricular zone (VZ/SVZ) and intermediate zone (IZ) of the dorsal telencephalon. Distal-less homeobox 2 (Dlx2) acted downstream of Ascl1 in promoting tangential migration along the VZ/SVZ but not IZ. We further identified Eph receptor B2 (Ephb2) as a direct target of Ascl1. Knockdown of EphB2 disrupted the separation of the VZ/SVZ and IZ migratory routes. Ephrin-A5, a ligand of EphB2, was sufficient to repel both Ascl1-expressing cells in vitro and tangentially migrating cortical interneurons in vivo. Together, our results demonstrate that Ascl1 induces expression of Dlx2 and Ephb2 to maintain distinct tangential migratory routes in the dorsal telencephalon. PMID:28276447

  20. Molecules and mechanisms that regulate multipolar migration in the intermediate zone.

    PubMed

    Cooper, Jonathan A

    2014-01-01

    Most neurons migrate with an elongated, "bipolar" morphology, extending a long leading process that explores the environment. However, when immature projection neurons enter the intermediate zone (IZ) of the neocortex they become "multipolar". Multipolar cells extend and retract cytoplasmic processes in different directions and move erratically-sideways, up and down. Multipolar cells extend axons while they are in the lower half of the IZ. Remarkably, the cells then resume radial migration: they reorient their centrosome and Golgi apparatus towards the pia, transform back to bipolar morphology, and commence locomotion along radial glia (RG) fibers. This reorientation implies the existence of directional signals in the IZ that are ignored during the multipolar stage but sensed after axonogenesis. In vivo genetic manipulation has implicated a variety of candidate directional signals, cell surface receptors, and signaling pathways, that may be involved in polarizing multipolar cells and stabilizing a pia-directed leading process for radial migration. Other signals are implicated in starting multipolar migration and triggering axon outgrowth. Here we review the molecules and mechanisms that regulate multipolar migration, and also discuss how multipolar migration affects the orderly arrangement of neurons in layers and columns in the developing neocortex.

  1. Oxidative modification of guanine bases initiated by oxyl radicals derived from photolysis of azo compounds.

    PubMed

    Shao, Jie; Geacintov, Nicholas E; Shafirovich, Vladimir

    2010-05-20

    Oxidative damage to guanine bases initiated by photolysis of the water-soluble radical generator 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) has been investigated by laser kinetic spectroscopy. In the neutral oxygenated aqueous solutions, 355 nm laser flash photolysis of AAPH generates a whole spectrum of free radicals including 2-amidinoprop-2-peroxyl (ROO(*)), 2-amidinoprop-2-oxyl (RO(*)), and superoxide (O(2)(*-)) radicals. These oxyl radicals with negligible absorption in a near UV-visible range were monitored in the reactions leading to the products with characteristic absorption spectra. This approach reveals that RO(*) radicals induce fast one-electron oxidation of 2'-deoxyguanosine (dG) to form guanine neutral radicals, dG(-H)(*). In contrast, ROO(*) radicals do not react at observable rates with dG. The O(2)(*-) radicals were detected using a classical test reaction with tetranitromethane to form nitroform. The major pathway for formation of the end-products of guanine oxidation is the combination of the G(-H)(*) and O(2)(*-) radicals to form 2,5-diamino-4H-imidazolone (Iz). This mechanism was confirmed by analysis of the end-products produced by oxidation of two substrates: (1) the guanosine derivative 2',3',5'-tri-O-acetylguanosine (tri-O-Ac-G) and (2) the 5'-d(CCATCGCTACC) sequence. The major products isolated by HPLC and identified by mass spectrometry methods were the tri-O-Ac-Iz and 5'-d(CCATC[Iz]CTACC products.

  2. Removal of tetrachloroethylene in an anaerobic column bioreactor.

    PubMed

    Noftsker, C; Watwood, M E

    1997-09-01

    Removal of tetrachloroethylene (perchloroethylene; C2Cl4) by microbial consortia from two sites with different C2Cl4 exposure histories was examined in a bench-scale anaerobic column bioreactor. It was hypothesized that optimal removal would be observed in the reactor packed with sediments having an extensive exposure history. Microbial consortia were enriched from hyporheic-zone (HZ) sediments from the Portneuf aquifer near Pocatello, Idaho, and from industrial-zone (IZ) sediments from a highly contaminated aquifer in Portland, Oregon. Lactate and acetate were the electron donors during experiments conducted over 9 and 7 months for HZ and IZ sediments, respectively. In the HZ bioreactor, the retention time ranged from 31 h to 81 h, and inlet C2Cl4 concentrations ranged from 0.1 ppm to 1.0 ppm. Dechlorination of C2Cl4 averaged 60% and reached a maximum of 78%. An increase in C:N from 27:1 to 500:1 corresponded to an 18% increase in removal efficiency. Trichloroethylene production corresponded to decreased effluent C2Cl4; further intermediates were not detected. In the IZ bioreactor, the retention time varied from 34 h to 115 h; the inlet C2Cl4 concentration was 1.0 ppm. C2Cl4 removal averaged 70% with a maximum of 98%. Trichloroethylene and cis-dichloroethylene were detected in the effluent. Increases in C:N from 50:1 to 250:1 enhanced dechlorination activity.

  3. Molecules and mechanisms that regulate multipolar migration in the intermediate zone

    PubMed Central

    Cooper, Jonathan A.

    2014-01-01

    Most neurons migrate with an elongated, “bipolar” morphology, extending a long leading process that explores the environment. However, when immature projection neurons enter the intermediate zone (IZ) of the neocortex they become “multipolar”. Multipolar cells extend and retract cytoplasmic processes in different directions and move erratically—sideways, up and down. Multipolar cells extend axons while they are in the lower half of the IZ. Remarkably, the cells then resume radial migration: they reorient their centrosome and Golgi apparatus towards the pia, transform back to bipolar morphology, and commence locomotion along radial glia (RG) fibers. This reorientation implies the existence of directional signals in the IZ that are ignored during the multipolar stage but sensed after axonogenesis. In vivo genetic manipulation has implicated a variety of candidate directional signals, cell surface receptors, and signaling pathways, that may be involved in polarizing multipolar cells and stabilizing a pia-directed leading process for radial migration. Other signals are implicated in starting multipolar migration and triggering axon outgrowth. Here we review the molecules and mechanisms that regulate multipolar migration, and also discuss how multipolar migration affects the orderly arrangement of neurons in layers and columns in the developing neocortex. PMID:25452716

  4. Influence of sodalite zeolite infiltration on the coefficient of thermal expansion and bond strength of all-ceramic dental prostheses.

    PubMed

    Naji, Ghassan Abdul-Hamid; Omar, Ros Anita; Yahya, Rosiyah

    2017-03-01

    In all-ceramic systems, a high incidence of veneer chip-off has been reported in clinical studies. Coefficient of thermal expansion (CTE) behaviour is one of the factors that may increase residual stress in the interface and influence the veneer/core bond strength. Therefore, this study aimed to evaluate the effect of sodalite zeolite-infiltration on the CTE behaviour and bond strength of different all-ceramic prostheses. The case-study groups were synthesized sodalite zeolite-infiltrated alumina (IA-SOD) and synthesized sodalite zeolite-infiltrated zirconia-toughened alumina (ZTA) (IZ-SOD), while the control groups were glass-infiltrated alumina (IA-glass) and glass-infiltrated ZTA (IZ-glass). Forty cylindrical-shaped samples measuring 5 mm in diameter and 10 mm in height were tested for CTE using a thermo-mechanical analyser machine, and forty disc-shaped ceramic samples measuring 12 mm in diameter and 1.2 ± 0.2 mm in thickness were prepared using specially designed stainless steel split mould and veneered by cylinder-shaped (2 mm high × 2 mm diameter) low-fusing porcelain (Vita VM7). The veneer/core samples were sintered and tested for shear bond strength using a high precision universal testing machine. Scanning electron microscope, stereo microscope, atomic force microscope, and energy-dispersive X-ray spectroscopy were used to investigate the structural characteristics of samples at the fracture surface. The collected data were analyzed with a one-way ANOVA and Tukey HSD test (α=.05). IZ-SOD revealed highest CTE and shear bond strength values, while the IA-glass revealed the lowest values than the other groups. There was no significant difference in CTE and bond strength among IZ-SOD, IA-SOD and IZ-glass samples (p>0.05). The experimental SOD zeolite-infiltrated samples revealed higher CTE mismatch and bond strength along with a more favourable mode of failure than did the commercial glass-infiltrated samples. Sandblast technique is considered as effective

  5. Genetic Diversity of Brucella Reference and Non-reference Phages and Its Impact on Brucella-Typing

    PubMed Central

    Hammerl, Jens A.; Göllner, Cornelia; Jäckel, Claudia; Scholz, Holger C.; Nöckler, Karsten; Reetz, Jochen; Al Dahouk, Sascha; Hertwig, Stefan

    2017-01-01

    Virulent phages have been used for many years to type Brucella isolates, but until recently knowledge about the genetic makeup of these phages remains limited. In this work the host specificity and genomic sequences of the original set (deposited in 1960) of VLA Brucella reference phages Tb, Fi, Wb, Bk2, R/C, and Iz were analyzed and compared with hitherto described brucellaphages. VLA phages turned out to be different from homonymous phages in other laboratories. The host range of the phages was defined by performing plaque assays with a wide selection of Brucella strains. Propagation of the phages on different strains did not alter host specificity. Sequencing of the phages TbV, FiV, WbV, and R/CV revealed nucleotide variations when compared to same-named phages previously described by other laboratories. The phages Bk2V and IzV were sequenced for the first time. While Bk2V exhibited the same deletions as WbV, IzV possesses the largest genome of all Brucella reference phages. The duplication of a 301 bp sequence in this phage and the large deletion in Bk2V, WbV, and R/CV may be a result of recombination caused by repetitive sequences located in this DNA region. To identify new phages as potential candidates for lysotyping, the host range and Single Nucleotide Polymorphisms (SNPs) of 22 non-reference Brucella phages were determined. The phages showed lysis patterns different from those of the reference phages and thus represent novel valuable candidates in the typing set. PMID:28360895

  6. Distribution, diversity and abundance of bacterial laccase-like genes in different particle size fractions of sediments in a subtropical mangrove ecosystem.

    PubMed

    Luo, Ling; Zhou, Zhi-Chao; Gu, Ji-Dong

    2015-10-01

    This study investigated the diversity and abundance of bacterial lacasse-like genes in different particle size fractions, namely sand, silt, and clay of sediments in a subtropical mangrove ecosystem. Moreover, the effects of nutrient conditions on bacterial laccase-like communities as well as the correlation between nutrients and, both the abundance and diversity indices of laccase-like bacteria in particle size fractions were also studied. Compared to bulk sediments, Bacteroidetes, Caldithrix, Cyanobacteria and Chloroflexi were dominated in all 3 particle-size fractions of intertidal sediment (IZ), but Actinobacteria and Firmicutes were lost after the fractionation procedures used. The diversity index of IZ fractions decreased in the order of bulk > clay > silt > sand. In fractions of mangrove forest sediment (MG), Verrucomicrobia was found in silt, and both Actinobacteria and Bacteroidetes appeared in clay, but no new species were found in sand. The declining order of diversity index in MG fractions was clay > silt > sand > bulk. Furthermore, the abundance of lacasse-like bacteria varied with different particle-size fractions significantly (p < 0.05), and decreased in the order of sand > clay > silt in both IZ and MG fractions. Additionally, nutrient availability was found to significantly affect the diversity and community structure of laccase-like bacteria (p < 0.05), while the total organic carbon contents were positively related to the abundance of bacterial laccase-like genes in particle size fractions (p < 0.05). Therefore, this study further provides evidence that bacterial laccase plays a vital role in turnover of sediment organic matter and cycling of nutrients.

  7. Transition from external imbricate zone to foreland thrust sheet in the Caledonides, N. Scandinavia

    NASA Astrophysics Data System (ADS)

    Rice, A. H. N.

    2010-05-01

    Thrust front geometries vary considerably between orogens, although erosion has usually removed external parts of the foreland thrust belt in older collision zones. This is the case in most of the Scandinavian Caledonides, where a well-defined basal decollement separates the nappe pile from the Autochthon. However, in both S and N Norway (E. Finnmark) thrust deformation dies out gradually towards the foreland. In Finnmark, the foreland thrust belt (Gaissa Thrust Belt) shows dominantly E-directed shortening. The internal part comprises the 50 km long (parallel to shortening) Munkavarri Imbricate Zone, with 50% shortening on 0.25-1.0 km spaced major imbricate thrusts. Minor thrusts/back-thrusts, are abundant near the basal decollement. Over ca. 12 km, major imbricate thrusts gradually cut up-section to lower stratigraphic levels, passing into tip-folds within the overlying Vuonjalrassa Thrust Sheet (20% shortening). The 10 km wide Låkkaskaidi Duplex (50% shortening), also underlies the Vuonjalrassa TS some 14 km to the foreland of the leading edge of the Munkavarri IZ. Stratigraphic overlap with the underlying Autochthon indicates that the Munkavarri IZ, Låkkaskaidi D and Vuonjalrassa TS were also transported en bloc towards the foreland by up to 25 km, along the Ruok'sadas Thrust. Below this, 20% shortening continues eastwards to the Hanadalen Thrust, in the footwall of which thrust ramps are no longer developed, although bedding-parallel slip continues further to the east. Sequentially, shortening in the Munkavarri IZ was likely of a continuously out-of-sequence nature, with all imbricate thrusts moving essentially together at the same time and older thrusts thus reaching higher stratigraphic levels as the basal decollement progressed towards the foreland. The decrease in shortening suggests a lower taper angle and/or faster thrust propagation. The cause of this is unknown, but much of the basal decollement under the Vuonjalrassa TS lies between pelitic rocks

  8. ADAM17 is critical for multipolar exit and radial migration of neuronal intermediate progenitor cells in mice cerebral cortex.

    PubMed

    Li, Qingyu; Zhang, Zhengyu; Li, Zengmin; Zhou, Mei; Liu, Bin; Pan, Le; Ma, Zhixing; Zheng, Yufang

    2013-01-01

    The radial migration of neuronal progenitor cells is critical for the development of cerebral cortex layers. They go through a critical step transforming from multipolar to bipolar before outward migration. A Disintegrin and Metalloprotease 17 (ADAM17) is a transmembrane protease which can process many substrates involved in cell-cell interaction, including Notch, ligands of EGFR, and some cell adhesion molecules. In this study, we used in utero electroporation to knock down or overexpress ADAM17 at embryonic day 14.5 (E14.5) in neuronal progenitor cells to examine the role of ADAM17 in cortical embryonic neurogenesis. Our results showed that the radial migration of ADAM17-knocked down cells were normal till E16.5 and reached the intermediate zone (IZ). Then most transfected cells stopped migration and stayed at the IZ to inner cortical plate (CP) layer at E18.5, and there was higher percentage of multipolar cells at IZ layer in the ADAM17-knocked down group compared to the cells in control group. Marker staining revealed that those ADAM17-knocked down cells differentiated normally from neural stem cells (NSCs) to neuronal intermediate progenitor cells (nIPCs) but did not differentiate into mature neurons. The migration and multipolar exit defects caused by ADAM17 knockdown could be partially rescued by over-expressing an shRNA resistant ADAM17, while overexpressing ADAM17 alone did not affect the radial migration. Taken together, our results showed for the first time that, ADAM17 is critical in regulating the multipolar-stage exit and radial migration of the nIPCs during telencephalon cortex development in mice.

  9. Metabolic engineering of Zymomonas mobilis for 2,3-butanediol production from lignocellulosic biomass sugars

    SciTech Connect

    Yang, Shihui; Mohagheghi, Ali; Franden, Mary Ann; Chou, Yat -Chen; Chen, Xiaowen; Dowe, Nancy; Himmel, Michael E.; Zhang, Min

    2016-09-02

    To develop pathways for advanced biofuel production, and to understand the impact of host metabolism and environmental conditions on heterologous pathway engineering for economic advanced biofuels production from biomass, we seek to redirect the carbon flow of the model ethanologen Zymomonas mobilis to produce desirable hydrocarbon intermediate 2,3-butanediol (2,3-BDO). 2,3-BDO is a bulk chemical building block, and can be upgraded in high yields to gasoline, diesel, and jet fuel. 2,3-BDO biosynthesis pathways from various bacterial species were examined, which include three genes encoding acetolactate synthase, acetolactate decarboxylase, and butanediol dehydrogenase. Bioinformatics analysis was carried out to pinpoint potential bottlenecks for high 2,3-BDO production. Different combinations of 2,3-BDO biosynthesis metabolic pathways using genes from different bacterial species have been constructed. Our results demonstrated that carbon flux can be deviated from ethanol production into 2,3-BDO biosynthesis, and all three heterologous genes are essential to efficiently redirect pyruvate from ethanol production for high 2,3-BDO production in <i>Z. mobilis. The down-selection of best gene combinations up to now enabled <i>Z. mobilis to reach the 2,3-BDO production of more than 10 g/L from glucose and xylose, as well as mixed C6/C5 sugar streams derived from the deacetylation and mechanical refining process. In conclusion, this study confirms the value of integrating bioinformatics analysis and systems biology data during metabolic engineering endeavors, provides guidance for value-added chemical production in <i>Z. mobilis, and reveals the interactions between host metabolism, oxygen levels, and a heterologous 2,3-BDO biosynthesis pathway. Taken together, this work provides guidance for future metabolic engineering efforts aimed at boosting 2,3-BDO titer anaerobically.

  10. DES J0454-4448: discovery of the first luminous z ≥ 6 quasar from the Dark Energy Survey

    SciTech Connect

    Reed, S. L.; McMahon, R. G.; Banerji, M.; Becker, G. D.; Gonzalez-Solares, E.; Martini, P.; Ostrovski, F.; Rauch, M.; Abbott, T.; Abdalla, F. B.; Allam, S.; Benoit-Levy, A.; Bertin, E.; Buckley-Geer, E.; Burke, D.; Carnero Rosell, A.; da Costa, L. N.; D'Andrea, C.; DePoy, D. L.; Desai, S.; Diehl, H. T.; Doel, P.; Cunha, C. E.; Estrada, J.; Evrard, A. E.; Fausti Neto, A.; Finley, D. A.; Fosalba, P.; Frieman, J.; Gruen, D.; Honscheid, K.; James, D.; Kent, S.; Kuehn, K.; Kuropatkin, N.; Lahav, O.; Maia, M. A. G.; Makler, M.; Marshall, J.; Merritt, K.; Miquel, R.; Mohr, J.; Nord, B.; Ogando, R.; Plazas, A.; Romer, K.; Roodman, A.; Rykoff, E.; Sako, M.; Sanchez, E.; Santiago, B.; Schubnell, M.; Sevilla, I.; Smith, C.; Soares-Santos, M.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Tucker, D.; Walker, A.; Wechsler, R. H.

    2015-10-28

    We present the first results of a survey for high-redshift, z ≥ 6, quasars using izY multicolour photometric observations from the Dark Energy Survey (DES). Here we report the discovery and spectroscopic confirmation of the zAB, YAB = 20.2, 20.2 (M1450 = -26.5) quasar DES J0454-4448 with a redshift of z = 6.09±0.02 based on the onset of the Ly α forest and an H I near zone size of 4.1+1.1-1.2 proper Mpc. The quasar was selected as an i-band drop out with i-z = 2.46 and zAB < 21.5 from an area of ~300 deg2. It is the brightest of our 43 candidates and was identified for spectroscopic follow-up solely based on the DES i-z and z-Y colours. The quasar is detected by WISE and has W1AB = 19.68. The discovery of one spectroscopically confirmed quasar with 5.7 < z < 6.5 and zAB ≤ 20.2 is consistent with recent determinations of the luminosity function at z ~ 6. DES when completed will have imaged ~5000 deg2 to YAB = 23.0 (5σ point source) and we expect to discover 50–100 new quasars with z > 6 including 3–10 with z > 7 dramatically increasing the numbers of quasars currently known that are suitable for detailed studies.

  11. Nutrient and particle load estimates to Lake Tahoe (CA-NV, USA) for Total Maximum Daily Load establishment.

    PubMed

    Sahoo, G B; Nover, D M; Reuter, J E; Heyvaert, A C; Riverson, J; Schladow, S G

    2013-02-01

    The Lake Tahoe Total Maximum Daily Load (TMDL) requires detailed methodologies to identify sources of flows and pollutants (particles and nutrients) for estimating time-variant loads as input data for the Lake Tahoe clarity model. Based on field data and a modeling study, the major sources of pollutant loads include streams (three subdivisions of this category are urban, nonurban, and stream channel erosion), intervening zones (IZs) (two subdivisions of this category are urban and nonurban), atmosphere (wet and dry), groundwater and shoreline erosion. As Lake Tahoe remains well oxygenated year-round, the contribution of internal loading from the bottom sediments was considered minor. A comprehensive quantitative estimate for fine particle number (< 16 μm diameter) and nutrient (nitrogen and phosphorus) loading is presented. Uncertainties in the estimation of fine particle numbers and nutrients for different sources are discussed. Biologically available phosphorus and nitrogen were also evaluated. Urban runoff accounted for 67% of the total fine particle load for all sources making it the most significant contributor although total urban runoff was only 6%. Non-urban flows accounted for 94% of total upland runoff, but the nitrogen, phosphorus and fine sediment loadings were 18%, 47% and 12%, respectively of the total loadings. Atmospheric nitrogen, phosphorus, and fine particle loadings were approximately 57%, 20%, and 16%, respectively of the total loading. Among streams and IZs, IZ 8000, Upper Truckee River, Trout Creek, Blackwood Creek, and Ward Creek are the top fine particle, nitrogen and phosphorus contributors. The relative percentage contribution of inorganic fine particles from all sources based on annual average for the period 1994-2008 on size classes 0.5-1, 1-2, 2-4, 4-8, and 8-16 μm are 73%, 19%, 5%, 2%, and 1%, respectively. These results suggest clear priorities for resource managers to establish TMDL on sources and incoming pollutants and

  12. In-vitro Callus Propagation and Secondary Metabolite Quantification in Sericostoma pauciflorum.

    PubMed

    C Jain, Satish; Pancholi, Boskey; Jain, Renuka

    2012-01-01

    Sericostoma pauciflorum Stocks ex Wight (Family Boraginaceae) used against cancer, diabetes and known to be health promoter. Callus cultures have been established from the stem explants on Murashige and Skoog (MS) medium supplemented with 1.5 mg/L concentration of different growth hormone viz. kinetin (Kn), indole 3-acetic acid (IAA) and indole 3-butyric acid (IBA). At 6 weeks of age, these calli were harvested, dried and extracted successively in pet, ether, methanol and water. Extracts were dried, weighed (%) and analyzed for their bioefficacies. Antimicrobial activities were determined using agar well diffusion and antioxidant potentials by DPPH and FRAP methods. Among all the test extracts, the extract of stem callus raised on IBA found to be more effective whereas it's pet. ether extract showed appreciable activity against both the test bacteria and fungi (S. aureus- IZ 14.00 ± 0.57 mm and T. rubrum- 16.33 ± 0.32 mm), followed by methanol extract (S. aureus- IZ 13.00 ± 0.57 mm, A. niger and P. chrysogenum- IZ 16.66 mm in both). In antioxidant potentials, all aqueous extracts were more active where IBA and Kn extracts demonstrated 0.06 mg/mL IC50 value (% inhibition 93.30 and 92.70 respectively at 0.8 mg/mL concentration) with 366 ± 6.69 and 343 ± 3.34 ascorbic acid equivalent antioxidant potentials at 1 mg/mL concentration. Furthermore, the chemical profile of test extracts was carried out. The bioactive secondary metabolites, β-sitosterol and caffeic acid was isolated from culture tissue of 6 weeks-old callus, and their identification and confirmation was carried out by color reaction, TLC behavior and IR spectrum techniques.

  13. Computation of surface electrical potentials of plant cell membranes . Correspondence To published zeta potentials from diverse plant sources

    PubMed

    Kinraide; Yermiyahu; Rytwo

    1998-10-01

    A Gouy-Chapman-Stern model has been developed for the computation of surface electrical potential (psi0) of plant cell membranes in response to ionic solutes. The present model is a modification of an earlier version developed to compute the sorption of ions by wheat (Triticum aestivum L. cv Scout 66) root plasma membranes. A single set of model parameters generates values for psi0 that correlate highly with published zeta potentials of protoplasts and plasma membrane vesicles from diverse plant sources. The model assumes ion binding to a negatively charged site (R- = 0.3074 &mgr;mol m-2) and to a neutral site (P0 = 2.4 &mgr;mol m-2) according to the reactions R- + IZ &rlharr; RIZ-1 and P0 + IZ &rlharr; PIZ, where IZ represents an ion of charge Z. Binding constants for the negative site are 21, 500 M-1 for H+, 20,000 M-1 for Al3+, 2,200 M-1 for La3+, 30 M-1 for Ca2+ and Mg2+, and 1 M-1 for Na+ and K+. Binding constants for the neutral site are 1/180 the value for binding to the negative site. Ion activities at the membrane surface, computed on the basis of psi0, appear to determine many aspects of plant-mineral interactions, including mineral nutrition and the induction and alleviation of mineral toxicities, according to previous and ongoing studies. A computer program with instructions for the computation of psi0, ion binding, ion concentrations, and ion activities at membrane surfaces may be requested from the authors.

  14. Synthesis and Characterization of Thin Films.

    DTIC Science & Technology

    1987-07-10

    8217.- % 9 335 1T *.1 .33, 114 224 004 Z24 *444 ~iz2 a 200j. - .331 210 220 4 MRO.20 l’~ll.101 OCRI 1. 22 51. " 3r" 11 • 1iT ŗi "S 113 113 � •Si IAI Al...34 Journal of Applied Crystals 20 210 (1987). • R. Shinar, J. Shinar, H.S. Wu, and H.R. Shanks, "Electron Energy Loss .’-.’ Studies on RF Sputtered aGel...tellurium, gold, mercury, thallium, lead, bismuth, and polonium . Other materials, including organic materials, have been deposited using the ICB

  15. The Propagation of Slip Across Alpha/Beta Interfaces in Titanium Alloys.

    DTIC Science & Technology

    1981-12-01

    method. The first stage conusists. of ’jetting’ each surface of the disc (which is Munted on a stainless steel gauze) with a stream of electrolyte. rf the...temperature 30 mL sulphuric acid and ,.70 volts. 300 ml methanol ’Final polishing’ solution at <c-5O 0 C 15 ml sulphuric acid and "IZ volts. These...proposed to describe the crystallography of the austenite to martensite transformation in steels . Case Mb A twinning shear on every alternate (!2

  16. The United States, Saudi Arabia, and Arms: Prospects for Future Instability in the Alliance

    DTIC Science & Technology

    1993-12-01

    KShaqraI . Q Medinar #. UI U.A.E. /SS~AUDI ARABIA " Jeda Makkah i /’Layla I EASTERN_ TiMAKH RIYADH I PROVINCE -AI 0 OMAN BAHA , I - SUDANRed Seam ASIR...FORM 1473,84 MAR 83 APR edition may be used until exhausted security classification of this page All other editions are obsolete i UNCLASSIFIED Approved...instability in the region. D~ . . . .c ;aos ,iz i Din TABLE OF CONTENTS I . INTRODUCTION AND THE FORMATION OF THE HOUSE OF SAUD 1 A. BIRTH OF A NATION

  17. Low-Cost Deposition Methods for Transparent Thin-Film Transistors

    DTIC Science & Technology

    2003-09-26

    h ot p la te an n ea li n g. S E M X R D S ol ve n t P re -B ak e F in al B ak e X R D G ra in F ig . F ig . B ak e S iz e (n m ) 4. 5 4. 9 14 0◦ C...N. Basu, A. K. Batabyal , and A. K. Barua, “Properties of tin doped indium oxide thin films prepared by magnetron sputtering,” J. Appl. Phys., vol. 54

  18. Theoretical and Experimental Study of Thermoacoustic Engines

    DTIC Science & Technology

    1991-12-31

    medium as a collection of circular capillary tubes.t The generalization to capillary tubes of arbitrary geometry has recently been explored. 12 The...dxdy (SY Her Am is the cross-sectional ae of the resonance tube at point z, A is.the cross-sectional area of a single pore, 12 is porosity, K 8 a and...The pressure translation theorem is Pj(z-d) =Pj(z) (os(kd) - zin sin(kd)) (19) Heat and work flow are A= 5 To Iiz12( 2 1 + Npr IZ(z) 12 [Re (Z(z)* {FQ

  19. A Geometric Optics Model for Calculating the Field Strength of Electromagnetic Waves in the Presence of a Tropospheric Duct.

    DTIC Science & Technology

    1977-12-01

    any other person or corporation , or conveying any rights or permission to manufacture use, or sell any patented invention that may in any way be...which has been adapted from a ray tracing program developed by the MITRE Corporation . 9 - At regular intervals along the earth’s surface, which are...XMAX,YMAXNREPFNRAY,NPRO,!4PLOT,NGRAD I. <REF,KGRAD,KP.OT DIMENSION AHO(81 ,TT’. (8),XTL(8) , YTL (83 ,TLE(83 ,ZT. (1) DATA Y~iN,YsIz,SIZE/0.0,5.C0.1505

  20. Expressive Threat Detection Validation Framework

    DTIC Science & Technology

    2006-06-01

    iv ity N oi se , C...8 Dataset Name G ro up C on ne ct iv ity N oi se , C lu tte r D at as et S iz e Po pu la tio n Si ze Pa tte rn C om pl ex ity O bs er...Attack agency Interaction type \\ Source Fo cu se d su rv ei lla nc e Br oa d su rv ei lla nc e C on ne ct iv ity p ro vi de r O pe n so ur

  1. Stochastic Evolution Equations with Values on the Dual of a Countably Hilbert Nuclear Space.

    DTIC Science & Technology

    1986-07-01

    is bounded in (0,T) which implies that g(t) *is a function of bounded variation on [O,T]. Also clearly g(t) is a continuous function of t. Next...t)y + fT’ (s, t)A’W ds. t 0 SS Hence it only remains to prove that t Zt[(] = s [PsT(s,t) ]ds 0 is a process of bounded variation . It was shown in...0 and 0 t 0 t T Iz t[ ] -zt0 ] I CTDTTjj [jt (t- to) . Hence the process Zt [(] is of bounded variation on [0,T] for each T> 0. More- over since it

  2. An Efficient Exact Algorithm for the ’Least Squares Image Registration Problem

    DTIC Science & Technology

    1989-05-01

    Zika -i TECHNICAL REPORT SOL ,J-5 May 1989 DTI.C , SELECTE ’" JUN 0 619891 F• • Department of Operations Research Stanford University Stanford, CA...the two-dimensional image registration problem. If X is a two-dimensional vector , then let x = zI + iz2 = [1xI4,9,. be the corresponding complex number...product. Therefore (x, y) = x c y for complex numbers, (z, y) = zry for real k-dimensional vectors , and if A and B are real n x k matrices, then let

  3. Army Combat Capabilities Analysis COMCAP 85.

    DTIC Science & Technology

    1979-06-01

    al. a lam a a1.4 . 0...... .. .. .. a ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ 4 coaaaa( iaaa ~ l aaaaa l i .c Iz c da ca IV cm= a R o ca M i .i mam I~ C a *0 1 0 ma...a" lt - A a a aai C2c ;.I;a ac z: IN P -C 4 CrC cF, "I4 ~ D. IckC a J .0 C2~ a iaaa c0 0, i. a co a aclc , I a pc Ia ’sJ aa *1ag al 01 a/11 al M~~~d

  4. Environmental Impact Assessment Sandia Laboratories, New Mexico.

    DTIC Science & Technology

    1977-05-01

    Flora on Kirtland Air Force Base East 177 APPENDIX E -- Estimated Probability of Aircraft Impacting Oil Tank, East of - Albuquerque Airport East-West...facilities 27 4 Methane gas facility 30 5 Hydrogen tube-bank trailer 32 6 Liquid ammonia storage tanks 32 7 View of oil tank farm 1.4 miles from main runway at...Albuquerque International Airport 33 8 Million-gallon oil tank 33 9 • ’iZ eratcr with stack scrubbers 35 10 Technical Area II facilities 37 11

  5. Tutorial Guide: Computer Aided Structural Modeling (CASM). Version 1.01, Release Date - February 1990

    DTIC Science & Technology

    1990-09-01

    Lock Vertical I! I Beams On All Grid Lines Beference Menu (NI) zl Truss - Custom (NI) View Reference (NI) Arch (N I) Move Reference (NI) Rotate Reference...NI) : Modify .Qpening X- Brace (NI) Grid/Open Menu K- Brace (NI) =]"---: ’Define Grid Spread K (NI) I- I Add Main Grid Line Single Diagonal (NI) Add Sub...Grid Line Offset Diagonal (NI) . Add Qpening Floor/Roof Menu Knee Brace (NI) Surface Frame Menu (NI) I~z One-Way rF All Connections (NI) 1I Two-Way 7H

  6. Dose equations for shift-variant CT acquisition modes using variable pitch, tube current, and aperture, and the meaning of their associated CTDI{sub vol}

    SciTech Connect

    Dixon, Robert L.; Boone, John M.; Kraft, Robert A.

    2014-11-01

    Purpose: With the increasing clinical use of shift-variant CT protocols involving tube current modulation (TCM), variable pitch or pitch modulation (PM), and variable aperture a(t), the interpretation of the scanner-reported CTDI{sub vol} is called into question. This was addressed for TCM in their previous paper published by Dixon and Boone [Med. Phys. 40, 111920 (14pp.) (2013)] and is extended to PM and concurrent TCM/PM as well as variable aperture in this work. Methods: Rigorous convolution equations are derived to describe the accumulated dose distributions for TCM, PM, and concurrent TCM/PM. A comparison with scanner-reported CTDI{sub vol} formulae clearly identifies the source of their differences with the traditional CTDI{sub vol}. Dose distribution simulations using the convolution are provided for a variety of TCM and PM scenarios including a helical shuttle used for perfusion studies (as well as constant mA)—all having the same scanner-reported CTDI{sub vol}. These new convolution simulations for TCM are validated by comparison with their previous discrete summations. Results: These equations show that PM is equivalent to TCM if the pitch variation p(z) is proportional to 1/i(z), where i(z) is the local tube current. The simulations show that the local dose at z depends only weakly on the local tube current i(z) or local pitch p(z) due to scatter from all other locations along z, and that the “local CTDI{sub vol}(z)” or “CTDI{sub vol} per slice” do not represent a local dose but rather only a relative i(z) or p(z). The CTDI-paradigm does not apply to shift-variant techniques and the scanner-reported CTDI{sub vol} for the same lacks physical significance and relevance. Conclusions: While the traditional CTDI{sub vol} at constant tube current and pitch conveys useful information (the peak dose at the center of the scan length), CTDI{sub vol} for shift-variant techniques (TCM or PM) conveys no useful information about the associated dose

  7. CTC Sentinel. Volume 6, Issue 7, July 2013

    DTIC Science & Technology

    2013-07-01

    Lebanese media in December 2012 as “the ambassador of al-Qa`ida in Lebanon.”41 The three others were Abdullah al-Shukri and Abdul Aziz al-Masri from...Syria and Abdul Nasser Sanjar from Lebanon.42 Al-Dousari’s group may have been ambushed by the Syrian military, with one member killed and the others...seems, in the 16th century, Per- sian-language elegiac martyrology of Husayn Va`iz Ka- shifi, Garden of the Martyrs. See Syed Akbar Hyder, Reliv- ing

  8. Response of a Plain and Filled Elastomer (Solithane 113) to High Strain-Rate Compression, Shear, and Tension Loading.

    DTIC Science & Technology

    1981-01-01

    one study, 1 5 tensile fracture due to stress wave interaction was examined in a polycarbonate. Penny - shaped tensile cracks were observed in the...reasonable. In our calculations, we have approximated the response of the glass beads using Keough’s data on soda lime glass4 2 3(Po - 2.49 g/cm ) to...follows: 1 8 CLH a [(KH + 4/3 GH)/p]1 /2 (4.4) CSH = (GH/P)1 /2 (4.5) 52 <IZ 4I - 1 12 Soda Lime Glass Unfilled SolithaneCalculated 10 Filled

  9. Survey of Ada (Trademark)-Based PDLs (Program Design Language).

    DTIC Science & Technology

    1985-01-01

    Each of these may comprise a view of auxiliary or tangible referents. This leads to an abstract syntax closely 59 related to simple English grammar and...bqUNIT NuvOEMS 7NJnsBranch Drive 17021 Sioux Lane ’e 1 d __Suite 6(0OWCihr14ug D2P McLean, VA 22102 G tirhrM)28 ’a ~OLLOUG or" Ict NAME AND ADDRESS IZ...Mechanisms for indicating postponed decisions, such as TBD constructs and English narrative. 2) Mechanisms for expressing supplemental design information

  10. Seawalls, Bulkheads and Quaywalls. Design Manual 25.4.

    DTIC Science & Technology

    1981-07-01

    e M&C .ae~-CA ’~ ~ 0~AVP𔄃U&MCL~ e ~r *0 I,.O 6 P FIGURE 22 Types of Quaywalls (A Thru D) 25.4-41 E . CYC ~aV Li 6OrJ6kr IZ &P 91 -WYTO WOpc. G. iEJWrLC4...25.4-11 e . Drainage.................................25.4-11 f. Inundation of the Backfill..................25.4-11 g. Passive Resistance of Soil...ini Lieu of Anchor System...............25.4-17 e . Hard Bottom . . . .. .. .. .. .. .. .. ... 25.4-17 f. Soft Bottom..........................25.4-21 1

  11. 16-Inch Gun-Launched Anti-Satellite Weapon

    DTIC Science & Technology

    1982-06-01

    public release, distribution unlimited 16-Inch Gun-Launched Anti-Satellite Weapon by Joseph John Natale Lieutenant, United States Navy B.A., University...w N L- UN H LLWIrNO0W CCT’. W W W ww WuflswrSx’x 0 ma. 63 I I I IZ I - I M w I I I lIL, I-.. CI =1 w I 1 1--* CL M~ WW OD 0 CL CL CL ODV CL a It...Dr. L. V. Schmidt Assistant Secretary of the Navy Assistant for Engineering Technology (R. E. and S) Pentagon SE731 Washington, D.C. 20350 6

  12. Nonlinear Microwave Properties of Atomic Layer Controlled HTS Multilayers

    DTIC Science & Technology

    2008-04-14

    nm YBCO 160 nm YBCO 160 nm YBCO -160 -130 - 100 -70 -40 -10 0 10 20 30 Circulating power (dBm) N or m al iz ed IM D p ow er (d B m ) Single layer...film with each YBCO layer 160- nm thick interspersed with CeO2 buffer layers 40- nm thick, giving an aggregate thickness of 640 nm of YBCO . The...flux penetration and flux motion are sources of loss. Thickness dependence of IMD of YBCO

  13. Cost Estimates for Desert Shield/Desert Storm a Budgetary Analysis

    DTIC Science & Technology

    1991-12-01

    AD-A244 67511111111 I Ill Illll 11111111l11 I ,11 l NAVAL POSTGRADUATE SCHOOL Monterey, California Iz DTIC ?PXLECT R 9 JAN 2 1992 u THESIS Cost...Professor William R . Gates Professor Katsuaki L. Terasawa Second Reader: Professor Richard B. Doyle Approved for public release: distribution is unlimited. b...NAME OF RESPONSIBLE INDIVIDUAL 22b TELEPHONE (Include Area code) 22c OFFICE SYMBOL Professor William R . Gates (408) 646-2754 Code AS/GT DD FORM 1473.84

  14. Evaluating the O*NET Occupational Analysis System for Army Competency Development: Supplemental Appendices

    DTIC Science & Technology

    2008-07-01

    i 00 » i i a a « >>Z III £ , iZ h. Crt TJ bpe e d o f Li m b M ov e m en t S ta tic St re n gt h E xp io si ve St...CO -O ( bpe e d o t Li m b M ov e m en t S ta tic St re n gt h E xp lo si ve St re n gt h D yn a m ic St re n gt h Tr un k

  15. THz semiconductor-based front-end receiver technology for space applications

    NASA Technical Reports Server (NTRS)

    Mehdi, Imran; Siegel, Peter

    2004-01-01

    Advances in the design and fabrication of very low capacitance planar Schottky diodes and millimeter-wave power amplifiers, more accurate device and circuit models for commercial 3-D electromagnetic simulators, and the availability of both MEMS and high precision metal machining, have enabled RF engineers to extend traditional waveguide-based sensor and source technologies well into the TI-Iz frequency regime. This short paper will highlight recent progress in realizing THz space-qualified receiver front-ends based on room temperature semiconductor devices.

  16. Comments on IDA Paper P-2863, A Comparison Air Force Data Systems

    DTIC Science & Technology

    1993-08-01

    as IDA moves towards finalizing their report. I (• JL qJO M . GILLIG 4’ Air Force Program £Excutive Officer 2 Atch *for Combat Support Systems 1... M o- C IL m - (Au A -K M1I f- 11 4n I- 4D ’A 4C c 4C 4v us 4ý 4L K 4A > 4 4 0 1: 8inll- c -4 𔃽 C9 .5- bo(a4 Iz W- U -.1 U.1 b- FA.I- U)0 on- -a . - j ...Litton Computer Services ................................................................................. IV- 1 j A. Forwarding Letter

  17. Training Extract AFSC 791X0 Public Affairs.

    DTIC Science & Technology

    1985-09-01

    3- u’ h h0 0. 1.S- x t 5 0 ’ 1Z h 6 *4*4 AO -40- 0 *4 d 63*46 ui 1- 0 chiO.*- %n 4A Sx C I 0 0 041 x & 0 I hIz 0 0 Vi...J 0,4M W, I- us 31zhh ft- &A...8217 .,t tc. . . . . . .~ : tg t I . . * * -.****q , 44 - - ~ a O- 0 N 𔃺 NŔ OP- CDP Om- mu &I CID0 0 U’ =, w-4 -" N-M N IVN WI 1 ... N ~ ry fn in .4M. ryN

  18. Letters

    NASA Astrophysics Data System (ADS)

    1999-11-01

    Survey of Binary Azeotropes by Paul C. Yates Re: article by R. J. Glinski, C. W. Smith, and J. B. Cooke Cheating Probabilities? Probably Not by David J. Miller Re: a criticism by C. Jonah and a note by G. T. Rizzuto and F. Walters trans-Cyclohexane-1,2-diamine by Richard S. Treptow Re: article by P. J. Walsh, D. K. Smith, and C. Castello Micropreparation of [RuH2PPh3)4] by Francisco J. Arnáiz Re: article by D. E. Linn, Jr. The author replies D. E. Linn's response follows

  19. A Regularized Solution to Edge Detection.

    DTIC Science & Technology

    1985-05-01

    Fourier transform of f(x). Physically, the constraint of smoothness allows us to effectively eliminate the noise that creeps in, after, or during the...all this by taking the Fourier transform of equation 3.) It is straightforward to find the Green’s function of (5) which vanishes at plus and minus...infinity. This is given by =~,X e- IzIvX/Vi ’~ _ _ - (8) / Cos ,, 4 4 In Fourier space, the transform of R(z, )) can be obtained directly from (5): 17B

  20. A Survey of Biodynamic Test Devices and Methods,

    DTIC Science & Technology

    1984-04-01

    failure. Animal tests are especially valuable in suggesting injury mechanisms that can occur under specified occupant-vehicle configurations. Comparison...Frequency RanCe 27000iz e.4, Number 1 e.4.a, on sled 21/2q e.4.b. on subject/dumrly f. Other Parameters Monitoreo : LUNG PRESSURE. BELT FORCES I IJ I...4.a. on ile_ _ _ v.4.u. un s.uject/ourvy I. Other Parameters Monitoreo : 40 NATO/AGARD Impact Test Facility Survey ID #33 1. Name and Address of

  1. Advanced Scavenge Systems for an Integrated Engine Inlet Particle Separator

    DTIC Science & Technology

    1977-09-01

    INSTRUMENTAT10N............ .oooo.....& 117 TEST RIG FACILITY INSTALLAT ION ..................... 124 TEST PLA.N OUJTLINE. . ... . .. .. .. .. . ... IZ...CDD 40 - 00 COD 0 cc 0a co 0 im 0 00 0-4 < -i 4L B LA SECT ION I (HUB) I1- SECTION 2 2- SECTION 3 3- SECTION 4 4 SECTION 5 5 STACKING POINT L.o in...based on previous particle seoarator experienc*, the difference in separation ef~iciency from 20-percent scavenge to 25 percent scavenge is mall, and

  2. Federal Logistics Information System (FLIS) Procedures Manual. Volume 16, Logistics On-Line Access (LOLA) End-User Manual.

    DTIC Science & Technology

    1994-10-01

    C’) LU 00C E 0)0 Figure 4.1-06 Inquiry Processing Steps 16.4-8 DoD 4100.39-M Volume 16 CJ) w al W D W Iz zi 0 rWL 0 -C)Lzz(1 C) LUz *L 0 -J U LUC) I...BULLETIN TIME: 13:05 TO: SANDI FROM: ANGELA DATE: 03-MAR-93 MESSAGE NO: 46 SUBJ: . <MSG 2013> ENTER TEXT OR PRESS <PF5> TO CANCEL FI=HELP F2= F3=PREV MENU

  3. Predictors Related to Premature Attrition of Navy Recruits

    DTIC Science & Technology

    1973-08-01

    s differentiating men on the basis of subsequent effectiveness . The costs of ’Iz 4 7 - IHoiberg, et al B premature attrition are extremely high; the...8217PREDICTORS RELATED TO PREMATURE ATTRITION OF NAVY RECRUITS C. J. HYSHAM ’- N. H. BERRY r ~ REPORT NO. 73-48 NAVAL HELTH IESARCH, CENTER, SAW ltdoý...8217%O yALORNIAo 92152, NAVAL MEWICALAREEARCH ANO DEVELPPMENT COMMAND *j&8~~D~ARLN -~10 db13Wll.mb E PREDICTORS RELATED TO PREMATURE ATTRITION OF NAVY

  4. Zionism and Southern Lebanon: A Historical Perspective on Six Decades of Controversy

    DTIC Science & Technology

    1979-06-01

    191- I 12 -1:cnden: The Athione Press , 1969), p.36 Obee Zeine, The Strule for Aab indeRnenence, Plate o, which is a reproduction of the attached to...parties to ex-loit those resources and t e pressed colateral benefits to Lebanon res ltin- from Zionist exploitation, originated with the above passage... Press , iZ7E). The r::action of Great Britain to the Zionist 22?onie claim was predictably f’avorable. What4, aftralcod her own pr-ote&.ctorate at the

  5. Synchronization of chemical noise-sustained structures in asymmetrically coupled differential-flow reactors.

    PubMed

    Izús, Gonzalo G; Sánchez, Alejandro D

    2013-12-01

    The differential-flow-induced chemical instability is investigated in the context of two coupled reactors with cubic autocatalytic kinetics (the Gray-Scott model). Previous results for master-slave arrangement [Izús, Deza, and Sánchez, J. Chem. Phys. 132, 234112 (2010)] are extended in this study to include bidirectional coupling between reactions. Numerical simulations in the convectively unstable regime show that synchronized noise-sustained structures are developed in both reactors due to the selective amplification of noise. A theoretical analysis shows that the nature of the synchronization and the stability of the synchronized manifold are related with the properties of the critical modes.

  6. Experimental Studies of Graphite-Epoxy and Boron-Epoxy Angle Ply Laminates in Shear,

    DTIC Science & Technology

    1977-09-01

    SPECIMENS tr15 0 BIEP I.- TEST 63 RUN 6SHERjR STRtiN MNII*N") ~iTEST 535 RUN 7 STEST 536 RUIN a uu .OU3 .00’i � gull 0 .00 W- -,-mou .0 ! .02 01...0.9 SERSTRAIN (No) FIG. 16A SHEAR RESPONSE OF PLANAR SPECIMENS 1300 BIEP X03 I-z I7 .rr~~5Qr~csc o~i~70 SHE~f SIRAIN (N/tN TEST 18:SHR 53S5NS OUN 1UUR

  7. Guanine Oxidation in Double-stranded DNA by MnTMPyP/KHSO(5): At Least Three Independent Reaction Pathways.

    PubMed

    Lapi, A; Pratviel, G; Meunier, B

    2001-01-01

    In order to better define the mechanism and the products of guanine oxidation within DNA, we investigated the details of the mechanism of guanine oxidation by a metalloporphyrin, Mn-TMPyP, associated to KHSO(5) on oligonucleotides. We found that the three major products of guanine oxidation are formed by independent reaction routes. The oxidized guanidinohydantoin (1) and the proposed spiro compound 3 derivatives are not precursors of imidazolone lesion (Iz). These guanine lesions as well as their degradation products, may account for non-detected guanine oxidation products on oxidatively damaged DNA.

  8. Conceptual Design of Navy Floating Pier.

    DTIC Science & Technology

    1982-09-01

    in. A single point mooring system permanently anchors the structure. In 1981, a smaller concrete barge was built In Singapore and towed to Mexico . The...Ul CMINC-$ zee :;7 ,s: S. 1,- -1- 1f No. tONON6 100-14-- &. - I.Z3 Firf A ~~ (Z4.00),.14M - ro*ax % rp z o3- r-z N~~~I- T=1,06- -4z -5 F -’-’TWWCTUIEA L

  9. An Analysis of the Impact of Reliability and Maintainability on Maintenance Manpower Requirements and Mission Effectiveness for the F-16 Implementation by the Turkish Air Force

    DTIC Science & Technology

    1986-12-01

    the procurement of the F-16 started in 1984 with the signature of a Letter of 1N Acceptance (LOA) between Turkey and the United States . Under this...ORGANIZATION j(if appicable.) IZ7 ADDRESS (City, State . and ZIP Cod.) 10. SOURCE OF FUNDING NUMBERS PROGRAM IPROJECT ITASK IWORK UNIT ELEMENT NO. INO. INO...EFFECTIVENESS FOR THE F-16 IMPLEMENTATION BY THE TURKISH AIR FORCE THESIS Muammer Akpinar First Lieutenant, TUAF AFIT/GOR/OS/86D- 1 Approved for public

  10. Sequential Medical Trials Involving Paired Data.

    DTIC Science & Technology

    1979-05-22

    2.3.2 ) and (2.3.3). If at any time ~~~ = 1 — $ ( IZ I ) stop taking observations and for the remaining N-2t units of time use * the treatment in...stopping times are restricted to those for which t takes on the values t = (a~~ + no 2 ) ~~~~~ + Na 2/2) . When N is large the successive differences...John Petkau Department of Mathematics University of British Columbia SUMMARY A continuous time version of Anscombe ’ s formulation of the problem of

  11. N-Nitrosodimethylamine. Biodegradation

    DTIC Science & Technology

    1984-06-01

    ORGANIZATION NAME AND AODRESS 10. PROGRAM OLEMN T.-PROJECT’ TASK &!V WORK UNIT NUNSERSr-. US Arvy Natick R&D Center AH68 1)’IZ .02 W-61.: ATTN: STRNC-YEP...UNCLASSIF lED IS&. OECL ASSI FI C ATI ONDOWMGRADING SCHEDOULE Is. DISTRIBUTION STATEMENT (of ft Nt Report) Approved for public release, distribution ...unlimited. 17. DISTRIBUTION STATEMENT (o. the abstract entor.d In Block 20, It diffirent fom Reporf) • 1 -- IS. SUPPLEMENTARY NOTES It. KEY WORDS (Continue

  12. ACOSS Twelve (Active Control of Space Structures)

    DTIC Science & Technology

    1982-12-01

    Analysis 10 1-VII Controller Robustness Investigation 12 I 1-VIII Robustness Definitions 12 1-lX Loop Transfer Recover on 2-Mode Example 15 I- X ...Results 2-V Correlation of Test and Analysis 67 2-VI Model Sensitivity 67 x 6. 1.0 ANALYTICAL RESEARCH FOR CONTROL METHODOLOGY DEVELOPMENT (TASK 1.0...include more modes than previously considered. The three I ’kA",PSD location Ix, V. 1I( ?.Is, 1 12 IV, Z) x * V. i Z is. 1 9. 9 (Y. 21 a I?. Iz 1

  13. Spectral-Domain Analysis of Finite Frequency Selective Surfaces

    DTIC Science & Technology

    1989-08-01

    field will be a discrete spectrum of plane waves of the form, 3 ES(z > zt) = ( epq + eOO0p8Oq)e j (aPtx +fipqy)- oqZ, (5.1) 3 p,q = _,, where (5mn is...with the vector constants epq is due to the induced current on the printed surface radiating in the I presence of the dielect ic medium; and (2) the...are omitted here.Iz Figure 5.1. Arbitrary periodic surface surrounded by an N-layer dielectric medium. I To find the constants epq , the strategy is to

  14. High Torque-to-Inertia Servo System for Stabilizing Sensor Systems. Candidate Systems Include Missile Guidance, Surveillance, and Tracking

    DTIC Science & Technology

    1980-04-01

    larger/heavier sensor loads because volume within the semi - circle can be utilized for sensor packaging. (3) The sensor/load is physically attached...100 m z - L -120 om 0 S-20 --- 140 Mm m -- 200 -6 I-2 . 1101 . 0001 0 80 80 60 60 40 . 40 20 0 [ -80 -20 -100 _______________________PHASE____________...Since th center of rotation passes through the center of the diameter.of the semi - I circle, the moment of inertia is given by: r 2 Iz = in m = .085155

  15. Basic Processes of Plasma Propulsion.

    DTIC Science & Technology

    1987-08-01

    s T*S IFI /G i’ u A "m = - ILI l ~2 U0k.. ’~la BASIC PROCESSES OF PLASMA PROPULSION Herbert 0. Schrade Institut fir Raumfahrtsysteme Universitat...discharge channel with respect to a small disturbance. IZ4 q, , L No cl W) 03Cii >i 04 -9- Depending on the amouunt of e given in eqs. (la) and (Ib) and...available at the University of Stuttgart about a year ago. H. 0. Schrade, M. Auweter-Kurtz and H. L . Kurtz, "Basic Processes of Plasma Propulsion

  16. Issues Related to Recruitment of Enlisted Personnel for the Reserve Components. Volume 3. Methods Volume. Wave III.

    DTIC Science & Technology

    1981-03-01

    analyses are IzRs’id on samples of cal I records. Approxi- mrtely 50 perce,-nt of thc- NPS re-cords and 33 pe’ce,4nt of the PS re- cordis m~ 1’ sanpled...each block represented the nu’rer plus 74 backups. In the baseline study, a block conQsisted of 100 telephone numbers: one n -Iber pUs 90 backups...zip code structure of the design. 5. Every potential target name plus its associated backups constituted a single sampling block. The number of

  17. Antibody Responses in the Nonhuman Primate, Macaca Fascicularis, to Protein Toxins

    DTIC Science & Technology

    1990-05-01

    LITERATURE REVIEW A. General Animal models have been used in the past for investigation and manipulation of disease related parameters which cannot be... IgG4 A. The data reflect an expression of each subclass proportionally related to the total IgG response. to z z w z 01 U’) CD) C) (Ua 0s )S1A aGI 89...0, IgG2 +, IgG3 0, IgG4 A. The data reflect an expression of each subclass proportionally related to the total IgG response. 0O m z z, w U)Iz U) 2

  18. Ocean Magnetics: 1. Fundamental Survey and Estimates of Induction Phenomena

    DTIC Science & Technology

    1977-10-01

    detailed analy- sis for each of the many varieties of gyven flow u0 (Sec. 3). Var- ious approaches are appropriate for various flows ~ as indicated briefly...here. In shallow waters (KD < 1, W X Krg-D), bottom effects become important. The flow amplitude Zi0 hap, little depth variation, and the OM field...at depths IzI : 1/K r T2 /4, where, however, exponential decrease also becomes dominant. More I detailed curves will be found, for example, in Ref. 4

  19. Overview of High-Temperature Superconductivity: Theory, Surfaces, Interfaces and Bulk Systems

    DTIC Science & Technology

    1988-06-01

    superconductivity. The RVB theory has been amplified or modified in several ways [5,6,7], the details of which we won’t go into here. Rice and Wang [8] have...similar to those of RVB theory, but different from BCS theory. Rice and Wang , however, favor a phonon interaction which mediates the attraction between...36, 857. 7. Kotliar, G. Phys. Rev. B,1988, IZ, 3664. 8. Rice, M. J.; Wang , Y. R. Phys. Rev.-B, 1988, 37, 5893. 9. Coffey, L.; Cox, D. L. Phys. Rev

  20. The Shock and Vibration Digest. Volume 13, Number 9

    DTIC Science & Technology

    1981-09-01

    between self-excited and random parametric vibrations, and identification of oscillating and vibro- d a dP Tldxi impact systems are among the recent... impact oscillator with two symmetrical barriers with respect to the equilibrium position has been investi- + -:[2iz (J+f ) + [l+cf,(.)]X - 0 (26) gated...2(2T)] > ... (27) where e is the coefficient of restitution, X+ = -r _ = X(*±O), and the time of impact r* is deter- where the period T : Averaging

  1. Imaging of Ocean Waves by SAR

    DTIC Science & Technology

    1988-01-01

    SAR o Contract N00014-87-C-0687N TDTIC R.L. Schult iZ L E C T E F.S. Henyey -JAN 2 4 1989 J.A. Wright Center for Studies of Nonlinear Dynamics La...Waves by SAR R.L. Schult F.S. Henyey J.A. Wright Center for Studies of Nonlinear Dynamics La Jolla Institute 7855 Fay Avenue, Suite 320 La Jolla...TOWARD data. 467.abstract 7-13-󈨜 Imaging of Ocean Waves by SAR 1. Introduction Synthetic Aperture Radar images of long-wavelength features on the

  2. Combined Operations in the Korean War

    DTIC Science & Technology

    1989-04-24

    Research Cfice, 1952. Ministry of National Defense , Republic of Korea . The History of United Nations Forces in the Korean War. Volume VI, Seou 1: 1977. ,-,h...committed to repelling the North Korean and Chinese armies from the Republic of Korea (ROK). The Korean War was not anticipated and neither was the extent...Coaal: tior War Early on 25 June Iz)50 the North Korean People- Army =_NKPA launched an overwhelming invasion into the Repu’Tli,: cf Korea . Pres-.i,ent

  3. Embankment Criteria and Performance Report, Red River Watershed, Dierks Lake, Saline River, Arkansas

    DTIC Science & Technology

    1987-10-01

    120IZ, 110~ 2 1 ’/~L Area 9BArow MaterWa f _______________________ TRIAXIAL. COMPRESSION TEST REPORT tNs PORN I WAYe 2089 PRESt V IIO5NS AA1 OUSOLIETE...SOOSIAT ~O RC L~ GAI 0 ___ - ~/03-74 01-1.3 0113,0 1-73 --1433 65 l~zb-1* (I72A / o,-,,oso 01,7,o,-1., ,., al61- 1060 O|’ 7 1 L -90 .49 -- 󈧅-68 Z---r

  4. 9433 Design Pointing Anomaly. Volume II. Appendices

    DTIC Science & Technology

    1976-01-30

    CALIFORNIA 90278 This final report was submitted by TRW Defense and Space t ) Systems Group, One Space Park, Redondo Beach, CA 90278, under Contract F04701-75...NTIS G:A&I FOR THE COMMANDER T J E . FREYTAG, C.. ’- em Program Dir tot, DSCS * puty for Space Comm Systems UNCLASSIFIED SICURI.YY CL ASSIFVICATION Of...90278__ ___________ 11I. CONTROLLING OFFICE NAME AND AORE’sS r a iz t jSpace and Missile Systems Ognzton 3 Jan~A&Fy-476 Air Force Systems CommandI Loas

  5. State Estimation and Control of Conditionally Linear Systems,

    DTIC Science & Technology

    1984-04-01

    formula we have I: izv izv s t izv A t - e + iz f hl(T,y)e x (y))dT S t izv 2 t izv iz f e Tdv- f e Td . T 2 -s i.j .~~*.~ . - : r*-~ ----- K...3 (,y)dw T dv - f A 1(s,y)A 2Cs,y) A 3 (’,y)dw Tds 4..0 0 0 0 - . 7 2 S C (t,y,w) -- f A2(S,Y) f A3(s,y)dwds 50 0 W Note also that C4(t,y,w) and C5(t...1 22 30 0 2(0 3T (1.12) The arguments in (1.12) were omitted for brevity. From (1.8) it follows that t8 t * tD (x 0,wpy) (D t (xO+ A 6(t,y) + f A3 (s,y

  6. ApoER2 Controls Not Only Neuronal Migration in the Intermediate Zone But Also Termination of Migration in the Developing Cerebral Cortex.

    PubMed

    Hirota, Yuki; Kubo, Ken-Ichiro; Fujino, Takahiro; Yamamoto, Tokuo T; Nakajima, Kazunori

    2016-11-30

    Neuronal migration contributes to the establishment of mammalian brain. The extracellular protein Reelin sends signals to various downstream molecules by binding to its receptors, the apolipoprotein E receptor 2 (ApoER2) and very low-density lipoprotein receptor and exerts essential roles in the neuronal migration and formation of the layered neocortex. However, the cellular and molecular functions of Reelin signaling in the cortical development are not yet fully understood. Here, to gain insight into the role of Reelin signaling during cortical development, we examined the migratory behavior of Apoer2-deficient neurons in the developing brain. Stage-specific labeling of newborn neurons revealed that the neurons ectopically invaded the marginal zone (MZ) and that neuronal migration of both early- and late-born neurons was disrupted in the intermediate zone (IZ) in the Apoer2 KO mice. Rescue experiments showed that ApoER2 functions both in cell-autonomous and noncell-autonomous manners, that Rap1, integrin, and Akt are involved in the termination of migration beneath the MZ, and that Akt also controls neuronal migration in the IZ downstream of ApoER2. These data indicate that ApoER2 controls multiple processes in neuronal migration, including the early stage of radial migration and termination of migration beneath the MZ in the developing neocortex.

  7. An Algorithm for 353 Odor Detection Thresholds in Humans

    PubMed Central

    Sánchez-Moreno, Ricardo; Cometto-Muñiz, J. Enrique; Cain, William S.

    2012-01-01

    One hundred and ninety three odor detection thresholds, ODTs, obtained by Nagata using the Japanese triangular bag method can be correlated as log (1/ODT) by a linear equation with R2 = 0.748 and a standard deviation, SD, of 0.830 log units; the latter may be compared with our estimate of 0.66 log units for the self-consistency of Nagata's data. Aldehydes, acids, unsaturated esters, and mercaptans were included in the equation through indicator variables that took into account the higher potency of these compounds. The ODTs obtained by Cometto-Muñiz and Cain, by Cometto-Muñiz and Abraham, and by Hellman and Small could be put on the same scale as those of Nagata to yield a linear equation for 353 ODTs with R2 = 0.759 and SD = 0.819 log units. The compound descriptors are available for several thousand compounds, and can be calculated from structure, so that further ODT values on the Nagata scale can be predicted for a host of volatile or semivolatile compounds. PMID:21976369

  8. Resiliency to social defeat stress relates to the inter-strain social interaction and is influenced by season variation.

    PubMed

    Han, Qiuqin; Yang, Liu; Liu, Yan; Lv, Ning; Yu, Jin; Wu, Gencheng; Zhang, Yuqiu

    2014-02-21

    Exposure to social defeat (SD) stress exerts social avoidance and depressive disorders. Little is known about the relationship between resiliency to stressors and the inter-strain social interaction (SI) level. We hypothesized that SD resiliency is correlated with a high SI between the same strain. C57BL/6J mice experienced a 10-day period of SD stress by repeated CD-1 mice offensive. The susceptible mice exhibited significant social-avoidance behaviors with less time in interaction-zone (IZ) and lower social interaction ratio (SIR) toward the Target (CD-1 mice), while resilient ones exhibited similar social interaction to control mice. When the Target was C57BL/6J mouse, either susceptible or resilient mice spent more time in IZ and the inter-strain SI in the resilient group was significantly higher than the susceptible. Correlation analysis revealed a significantly non-zero slope of the linear relationship between SIRs toward two strains. But different groups had a similar baseline of the inter-strain SI before stress, indicating a SD-induced defect in both types of SI. In addition, in four different seasons, animals exhibited a significant resiliency to the stress in summer. These data suggest that SD resiliency is related to a higher SI toward the same-strain, and may be regulated by seasonal variations.

  9. Semi-synthesis of new antimicrobial esters from the natural oleanolic and maslinic acids.

    PubMed

    Chouaïb, Karim; Hichri, Fayçal; Nguir, Asma; Daami-Remadi, Majda; Elie, Nicolas; Touboul, David; Ben Jannet, Hichem; Hamza, M'hamed Ali

    2015-09-15

    In this article, we report an effective procedure for the selective isolation of oleanolic acid 1 and maslinic acid 2 (3.4 and 8.5mg/g DW, respectively) from pomace olive (Olea europaea L.) using an ultrasonic bath, and the synthesis of a series of new triterpenic acid esters. The compounds were characterized by their spectral data and were evaluated for their antimicrobial activity. Among the compounds tested, those having sulfur and chlorine atoms were found to be antibacterial. They showed activity against two Gram-positive bacteria Staphylococcus aureus and Enterococcus faecalis and two Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa (MICs within a range of 5-25μg/mL). The fungus Penicillium italicum was found to be the most sensitive to both sulfur derivatives: (3β)-3-((thiophene-2-carbonyl)oxy)-olean-12-en-28-oic acid (1a) (IZ=22mm) and (2α,3β-2,3-bis((thiophene-2-carbonyl)oxy)olean-12-en-28-oic acid (2a) (IZ=24mm).

  10. All Prime Contract Awards by State or Country, Place, and Contractor. Part 2 (Agnew, California-Loma Linda, California)

    DTIC Science & Technology

    1990-01-01

    W #-- W 0. 0) 1-1 ZII4EI0 I I 0 C4 11 0 iz 0 cc 0 2 00 0oil mU 1 0 " 1I- TL -4 I- w N N- ~ -41- 1- f- N 0 Q11 is 0 0 I 0a 04 It U 0) 00 0 00U 0 C. 0...4Le -4 0 r-l’- 44 < 4’" .-4<<~*-4 -4 (A M-4 I -i 42 - iZ -4222 -42* -4 z -422 -4ZZ2222z -422 -42 * ~ to 000 fui Ia a ZZZ* IaZ* lu2 fuzz* 40222222* fiaZZ...11..J0() 20) 0000)00-1 00 .1 0O 000)4 1.-)))000 - I0) 0 -A 0) F UA u00 CD- W (-44 4 Wj 2 < <- 4c < mU (140N 442 N-Ŕ- F.- 0 0 1-- < I- w $-- C C0 U I

  11. C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development.

    PubMed

    Shah, Bhavin; Lutter, Daniela; Bochenek, Magdalena L; Kato, Katsuhiro; Tsytsyura, Yaroslav; Glyvuk, Natalia; Sakakibara, Akira; Klingauf, Jürgen; Adams, Ralf H; Püschel, Andreas W

    2016-01-01

    The establishment of a polarized morphology is essential for the development and function of neurons. During the development of the mammalian neocortex, neurons arise in the ventricular zone (VZ) from radial glia cells (RGCs) and leave the VZ to generate the cortical plate (CP). During their migration, newborn neurons first assume a multipolar morphology in the subventricular zone (SVZ) and lower intermediate zone (IZ). Subsequently, they undergo a multi-to-bipolar (MTB) transition to become bipolar in the upper IZ by developing a leading process and a trailing axon. The small GTPases Rap1A and Rap1B act as master regulators of neural cell polarity in the developing mouse neocortex. They are required for maintaining the polarity of RGCs and directing the MTB transition of multipolar neurons. Here we show that the Rap1 guanine nucleotide exchange factor (GEF) C3G (encoded by the Rapgef1 gene) is a crucial regulator of the MTB transition in vivo by conditionally inactivating the Rapgef1 gene in the developing mouse cortex at different time points during neuronal development. Inactivation of C3G results in defects in neuronal migration, axon formation and cortical lamination. Live cell imaging shows that C3G is required in cortical neurons for both the specification of an axon and the initiation of radial migration by forming a leading process.

  12. Excitatory cortical neurons with multipolar shape establish neuronal polarity by forming a tangentially oriented axon in the intermediate zone.

    PubMed

    Hatanaka, Yumiko; Yamauchi, Kenta

    2013-01-01

    The formation of axon-dendrite polarity is crucial for neuron to make the proper information flow within the brain. Although the processes of neuronal polarity formation have been extensively studied using neurons in dissociated culture, the corresponding developmental processes in vivo are still unclear. Here, we illuminate the initial steps of morphological polarization of excitatory cortical neurons in situ, by sparsely labeling their neuroepithelial progenitors using in utero electroporation and then examining their neuronal progeny in brain sections and in slice cultures. Morphological analysis showed that an axon-like long tangential process formed in progeny cells in the intermediate zone (IZ). Time-lapse imaging analysis using slice culture revealed that progeny cells with multipolar shape, after alternately extending and retracting their short processes for several hours, suddenly elongated a long process tangentially. These cells then transformed into a bipolar shape, extending a pia-directed leading process, and migrated radially leaving the tangential process behind, which gave rise to an "L-shaped" axon. Our findings suggest that neuronal polarity in these cells is established de novo from a nonpolarized stage in vivo and indicate that excitatory cortical neurons with multipolar shape in the IZ initiate axon outgrowth before radial migration into the cortical plate.

  13. Further perspective on the theory of heteronuclear decoupling

    NASA Astrophysics Data System (ADS)

    Skinner, Thomas E.

    2014-11-01

    An exact general theory of heteronuclear decoupling is presented for spin-1/2 IS systems. RF irradiation applied to the I spins both modifies and generates additional couplings between states of the system. The recently derived equivalence between the dynamics of any N-level quantum system and a system of classical coupled harmonic oscillators makes explicit the exact physical couplings between states. Decoupling is thus more properly viewed as a complex intercoupling. The sign of antiphase magnetization plays a fundamental role in decoupling. A one-to-one correspondence is demonstrated between ± 2SyIz and the sense of the S-spin coupling evolution. Magnetization Sx is refocused to obtain the desired decoupled state when ∫ 2SyIz dt = 0 . The exact instantaneous coupling at any time during the decoupling sequence is readily obtained in terms of the system states, showing that the creation of two-spin coherence is crucial for reducing the effective scalar coupling, as required for refocusing to occur. Representative examples from new aperiodic sequences as well as standard cyclic, periodic composite-pulse and adiabatic decoupling sequences illustrate the decoupling mechanism. The more general aperiodic sequences, obtained using optimal control, realize the potential inherent in the theory for significantly improved decoupling.

  14. Nanog expression in heart tissues induced by acute myocardial infarction.

    PubMed

    Luo, Huanhuan; Li, Qiong; Pramanik, Jogen; Luo, Jiankai; Guo, Zhikun

    2014-10-01

    Nanog is a potential stem cell marker and is considered a regeneration factor during tissue repair. In the present study, we investigated expression patterns of nanog in the rat heart after acute myocardial infarction by semi-quantitative RT-PCR, immunohistochemistry and Western blot analyses. Our results show that nanog at both mRNA and protein levels is positively expressed in myocardial cells, fibroblasts and small round cells in different myocardial zones at different stages after myocardial infarction, showing a spatio-temporal and dynamic change. After myocardial infarction, the nanog expression in fibroblasts and small round cells in the infarcted zone (IZ) is much stronger than that in the margin zone (MZ) and remote infarcted zone (RIZ). From day 7 after myocardial infarction, the fibroblasts and small cells strongly expressed nanog protein in the IZ, and a few myocardial cells in the MZ and the RIZ and the numbers of nanog-positive fibroblasts and small cells reached the highest peak at 21 days after myocardial infarction, but in this period the number of nanog-positive myocardial cells decreased gradually. At 28 days after myocardial infarction, the numbers of all nanog-positive cells decreased into a low level. Therefore, our data suggest that all myocardial cells, fibroblasts and small round cells are involved in myocardial reconstruction after cardiac infarction. The nanog-positive myocardial cells may respond to early myocardial repair, and the nanog-positive fibroblasts and small round cells are the main source for myocardial reconstruction after cardiac infarction.

  15. Tailoring the optimal control cost function to a desired output: application to minimizing phase errors in short broadband excitation pulses.

    PubMed

    Skinner, Thomas E; Reiss, Timo O; Luy, Burkhard; Khaneja, Navin; Glaser, Steffen J

    2005-01-01

    The de facto standard cost function has been used heretofore to characterize the performance of pulses designed using optimal control theory. The freedom to choose new, creative quality factors designed for specific purposes is demonstrated. While the methodology has more general applicability, its utility is illustrated by comparison to a consistently chosen example--broadband excitation. The resulting pulses are limited to the same maximum RF amplitude used previously and tolerate the same variation in RF homogeneity deemed relevant for standard high-resolution NMR probes. Design criteria are unchanged: transformation of I(z)--> I(x) over resonance offsets of +/-20 kHz and RF variability of +/-5%, with a peak RF amplitude equal to 17.5 kHz. However, the new cost effectively trades a small increase in residual z magnetization for improved phase in the transverse plane. Compared to previous broadband excitation by optimized pulses (BEBOP), significantly shorter pulses are achievable, with only marginally reduced performance. Simulations transform I(z) to greater than 0.98 I(x), with phase deviations of the final magnetization less than 2 degrees, over the targeted ranges of resonance offset and RF variability. Experimental performance is in excellent agreement with the simulations.

  16. Exogenous Reelin modifies the migratory behavior of neurons depending on cortical location.

    PubMed

    Britto, Joanne M; Tait, Karen J; Lee, Ean Phing; Gamble, Robin S; Hattori, Mitsuharu; Tan, Seong-Seng

    2014-11-01

    Malformations of cortical development can arise when projection neurons generated in the germinal zones fail to migrate properly into the cortical plate. This process is critically dependent on the Reelin glycoprotein, which when absent leads to an inversion of cortical layers and blurring of borders. Reelin has other functions including supporting neuron migration and maintaining their trajectories; however, the precise role on glial fiber-dependent or -independent migration of neurons remains controversial. In this study, we wish to test the hypothesis that migrating cortical neurons at different levels of the cortical wall have differential responses to Reelin. We exposed neurons migrating across the cortical wall to exogenous Reelin and monitored their migratory behavior using time-lapse imaging. Our results show that, in the germinal zones, exogenous Reelin retarded neuron migration and altered their trajectories. This behavior is in contrast to the response of neurons located in the intermediate zone (IZ), possibly because Reelin receptors are not expressed in this zone. In the reeler cortex, Reelin receptors are expressed in the IZ and exposure to exogenous Reelin was able to rescue the migratory defect. These studies demonstrate that migrating neurons have nonequivalent responses to Reelin depending on their location within the cortical wall.

  17. An ultrastructural study of connective tissue in mollusc integument III. Cephalopoda.

    PubMed

    Bairati, A; Comazzi, M; Gioria, M

    2003-06-01

    We studied structure and ultrastructure of the subepidermal connective tissue (SEC) of the integument of three cephalopods (Sepia officinalis, Octopus vulgaris and Loligo pealii). In all species, three distinct regions of the SEC were recognised: (a) an outer zone (OZ) that included the dermal-epidermal junction, and consisted of a thin layer of connective tissue containing muscles, (b) an extensive middle zone (MZ) containing a compact network of collagen fibres and numerous cells, (c) an inner zone (IZ) of loose connective tissue that merged with muscular fascia. This arrangement differs from that in bivalves and gastropods and recalls vertebrate integument. The dermal-epidermal junction of cephalopods differed from that of bivalves, gastropods and mammals in that the epidermal cells did not possess hemidesmosomes, and their intermediate filaments terminated directly in the plasmamembrane. The thick (120-500 nm) basal membrane (BM) had a superficial zone containing a regular array of granules; a lamina densa composed of a compact network of small filaments and granules; and an IZ distinguished by expansions of granular material protruding into underlying structures. Collagen fibres contained fibroblast-derived cytoplasmic thread, running through their centres and were surrounded by granular material that joins them to adjacent fibres. The collagen fibrils were of medium diameter (30-80 nm) had the typical ultrastructure of fibrillar collagens, and were surrounded by abundant interfibrillar material. The hypodermis was loose, with a network of small bundles of collagen fibrils. Cephalopod integument appears to represent a major evolutionary step distinguishing this class of molluscs.

  18. Nanotribological response of a plasma nitrided bio-steel.

    PubMed

    Samanta, Aniruddha; Chakraborty, Himel; Bhattacharya, Manjima; Ghosh, Jiten; Sreemany, Monjoy; Bysakh, Sandip; Rane, Ramkrishna; Joseph, Alphonsa; Jhala, Ghanshyam; Mukherjee, Subroto; Das, Mitun; Mukhopadhyay, Anoop K

    2017-01-01

    AISI 316L is a well known biocompatible, austenitic stainless steel (SS). It is thus a bio-steel. Considering its importance as a bio-prosthesis material here we report the plasma nitriding of AISI 316L (SS) followed by its microstructural and nanotribological characterization. Plasma nitriding of the SS samples was carried out in a plasma reactor with a hot wall vacuum chamber. For ease of comparison these plasma nitrided samples were termed as SSPN. The experimental results confirmed the formations of an embedded nitrided metal layer zone (ENMLZ) and an interface zone (IZ) between the ENMLZ and the unnitrided bulk metallic layer zone (BMLZ) in the SSPN sample. These ENMLZ and IZ in the SSPN sample were richer in iron nitride (FeN) chromium nitride (CrN) along with the austenite phase. The results from nanoindentation, microscratch, nanoscratch and sliding wear studies confirmed that the static contact deformation resistance, the microwear, nanowear and sliding wear resistance of the SSPN samples were much better than those of the SS samples. These results were explained in terms of structure-property correlations.

  19. Re-evaluation of EMG-torque relation in chronic stroke using linear electrode array EMG recordings.

    PubMed

    Bhadane, Minal; Liu, Jie; Rymer, W Zev; Zhou, Ping; Li, Sheng

    2016-06-28

    The objective was to re-evaluate the controversial reports of EMG-torque relation between impaired and non-impaired sides using linear electrode array EMG recordings. Ten subjects with chronic stroke performed a series of submaximal isometric elbow flexion tasks. A 20-channel linear array was used to record surface EMG of the biceps brachii muscles from both impaired and non-impaired sides. M-wave recordings for bilateral biceps brachii muscles were also made. Distribution of the slope of the EMG-torque relations for the individual channels showed a quasi-symmetrical "M" shaped pattern. The lowest value corresponded to the innervation zone (IZ) location. The highest value from the slope curve for each side was selected for comparison to minimize the effect of electrode placement and IZ asymmetry. The slope was greater on the impaired side in 4 of 10 subjects. There were a weak correlation between slope ratio and strength ratio and a moderate to high correlation between slope ratio and M-wave ratio between two sides. These findings suggest that the EMG-torque relations are likely mediated and influenced by multiple factors. Our findings emphasize the importance of electrode placement and suggest the primary role of peripheral adaptive changes in the EMG-torque relations in chronic stroke.

  20. Antimicrobial Activity of a Neem Cake Extract in a Broth Model Meat System

    PubMed Central

    Del Serrone, Paola; Nicoletti, Marcello

    2013-01-01

    This work reports on the antimicrobial activity of an ethyl acetate extract of neem (Azadirachta indica) cake (NCE) against bacteria affecting the quality of retail fresh meat in a broth model meat system. NCE (100 µg) was also tested by the agar disc diffusion method. It inhibited the growth of all tested microorganisms. The NCE growth inhibition zone (IZ) ranged 11.33–22.67 mm while the ciprofloxacin (10 µg) IZ ranged from 23.41–32.67 mm. There was no significant difference (p ≤ 0.05) between the antimicrobial activity of NCE and ciprofloxacin vs. C. jejuni and Leuconostoc spp. The NCE antibacterial activity was moreover determined at lower concentrations (1:10–1:100,000) in micro-assays. The percent growth reduction ranged from 61 ± 2.08–92 ± 3.21. The higher bacterial growth reduction was obtained at 10 µg concentration of NCE. Species-specific PCR and multiplex PCR with the DNA dye propidium monoazide were used to directly detect viable bacterial cells from experimentally contaminated meat samples. The numbers of bacterial cells never significantly (p ≤ 0.05) exceeded the inocula concentration used to experimentally contaminate the NCE treated meat. This report represents a screening methodology to evaluate the antimicrobial capability of a herbal extract to preserve meat. PMID:23917814

  1. Selection of a suitable plant for phytoremediation in mining artisanal zones.

    PubMed

    Chamba, I; Gazquez, M J; Selvaraj, T; Calva, J; Toledo, J J; Armijos, C

    2016-09-01

    A study was undertaken with the aim of identifying a suitable plant for the phytoremediation of metal-polluted soil from an artisanal mining area in Ecuador. Three zones including a natural zone (NZ), abandoned zone (AZ) and intensively mined zone (IZ) were selected. Three common native plants grown in the three zones were identified and collected, including Miconia zamorensis, Axonopus compressus and Erato polymnioides. The percentage of arbuscular mycorrhizal colonization that benefits their own survival in polluted soil was analyzed in the root samples of these candidate species. Analysis of the soils and plants collected from the different zones showed that the concentrations of Pb, Zn, Cu and Cd were comparatively lower in the NZ, higher in the AZ and IZ, and highest in the AZ for all the metals. The concentration of all these metals in plant tissues was the highest in E. polymnioides. The data analysis including the metal accumulation index, bioconcentration factor and translocation factor strongly identified E. polymnioides as a hyperaccumulator plant suitable for phytoremediation.

  2. Dose equations for tube current modulation in CT scanning and the interpretation of the associated CTDI{sub vol}

    SciTech Connect

    Dixon, Robert L.; Boone, John M.

    2013-11-15

    Purpose: The scanner-reported CTDI{sub vol} for automatic tube current modulation (TCM) has a different physical meaning from the traditional CTDI{sub vol} at constant mA, resulting in the dichotomy “CTDI{sub vol} of the first and second kinds” for which a physical interpretation is sought in hopes of establishing some commonality between the two.Methods: Rigorous equations are derived to describe the accumulated dose distributions for TCM. A comparison with formulae for scanner-reported CTDI{sub vol} clearly identifies the source of their differences. Graphical dose simulations are also provided for a variety of TCM tube current distributions (including constant mA), all having the same scanner-reported CTDI{sub vol}.Results: These convolution equations and simulations show that the local dose at z depends only weakly on the local tube current i(z) due to the strong influence of scatter from all other locations along z, and that the “local CTDI{sub vol}(z)” does not represent a local dose but rather only a relative i(z) ≡ mA(z). TCM is a shift-variant technique to which the CTDI-paradigm does not apply and its application to TCM leads to a CTDI{sub vol} of the second kind which lacks relevance.Conclusions: While the traditional CTDI{sub vol} at constant mA conveys useful information (the peak dose at the center of the scan length), CTDI{sub vol} of the second kind conveys no useful information about the associated TCM dose distribution it purportedly represents and its physical interpretation remains elusive. On the other hand, the total energy absorbed E (“integral dose”) as well as its surrogate DLP remain robust between variable i(z) TCM and constant current i{sub 0} techniques, both depending only on the total mAs =t{sub 0}=i{sub 0} t{sub 0} during the beam-on time t{sub 0}.

  3. A Numerical Model for the Computation of Radiance Distributions in Natural Waters with Wind-Roughened Surfaces, Part 2: User’s Guide and Code Listing

    DTIC Science & Technology

    1988-07-01

    AAM) AT ALL Y LEVELS WRITE(NOUT) (AAM(I).I=1, NRAMP ) 00 150 J=1.NV 150 WRITE(NUOUT) (AYM(I .J) ,I11, NRAMP ) IF(IDBLJG2.NE.0) THIEN WRITEC6. 1038) CALL...COMPUTATIONS C C SAVE THE COMPuILO AMP’ ITubES C WRITE(NUOUT) (WERK(I) ,I I, NRAMP ) WRITE(NUOUT) (AAM) I), I1 , NRAMP ) WRITE (NUOUT) (AAP (I) .I=1. NRAMP ) DO...450 J=1,NY 450 wRITE(NuOUT) (A\\’M(I ,.),Iz.1, NRAMP ) 00 451 j=l.Ny 451 vyRITE NjOUT) (AYPL(I .j),I 1,NkAMP) ENDFILE NUOUT IF(IDBUG2.NE.(ni T,-EN WRITE

  4. Economics of Chlorofluorocarbon (CFC) Machine Replacement

    DTIC Science & Technology

    1994-09-01

    O4(Q( ID 0ý 0DN mCa0 _ 4$ U (.4 * CImM -L~4 D .. (3 0 0 0 4)U 0 iz0 0. u 410 U uOrW~4 = N4 LALA 0-4 0 Col r *-Lnr-4M m ’ 0 % %’D ~ LA 0: C, .. M, LAn... 2009 . Simply running the model and taking action several years in the future is not feasible. Because of the volitile refrigerant market, extending to... 2009 $2,564 $5,129 $7,693 $10,258 $12,822 2010 $2,683 $5,366 $8,049 $10,732 $13,415 2011 $2,801 $5,601 $8,402 $11,203 $14,004 2012 $2,919 $5,838 $8,757

  5. The Kinetics of Evolution of Water Vapor Clusters in Air

    DTIC Science & Technology

    1975-12-01

    neighbor coordination number. (1)2/In the ther---dynamic li -mit of size(1 (g--), Kg-l=g/, a =(361r/g) 1/3 and X =A. giving the asymptotic values...t.. -4 I-a Nw NN - a-~~~ 0 LI .4 - - - 4 1;. a-a I D 0 0 0 CD 0 43 04r 4 -s C4 𔃾ca-4i 0~ 0 -4 00 .- 4~0% to N 000 4 o * 3 0 ’ -4 1J t. -44 izOto H...flow rate is simply Au. The quantity d( Li v)/dt is thus given by S(In v) = (In Au). V-2.4 Since d in y/dr 1 /y dy/dt, hence •] d 1 Au du dA d AuA=+u

  6. Fastener Hole Quality. Volume 2

    DTIC Science & Technology

    1978-12-01

    i TEST TRAM: 1. 2T 4 5 O Z7W AVER~ AGE VIMRT: 3.07 060 0191o z AVERAGE Tcxs-.,Si 2 860 n i4.*k- 2760 (nI2 o _______ AREA:_____ 2660_______ BASELINE...LOAD: 19777 goAn (n ag ,•’ 71 gn 4o ( 7 3 , - CYCLES AT TERMINATION/ IZ: 3Ives/_ ___n l’ A D 2,7.7 l’ 1so: I I _Z. 1680 -066s 6 at?- .. ign 0!𔃿t7...TEST DATE: _-32 12800 2-6 _. , 31 1240030 12000 6 1d RAG WIDTH: S.oo( -29 11600 6 % OtO c5 n 1l AGE 28 11200 1 % I do t4-S,7/78,... -2ś 10so00

  7. A User’s Guide to CERC’s Field Research Facility.

    DTIC Science & Technology

    1981-10-01

    from U.S. Geological Survey, USGS, luaps NJ 18-8, -11; NI 18-2). 22 d. Vehicle Use and Rentals. Vehicles with an axle width less than 3.1 meters and a...weight under 900 kilograms (2,000 pounds) per wheel may be driven on the pier with permission of the FRF Chief. Beach access is provided just south of...50501, C.C. , *’Coastal V, ,Ittit inn11, A( o i, Ir1 r,,ii~C5 a,,nt L l.i, nirn L cr :2 t’ I nO~i-Io Fnvtlir ont Inventors .: -t;iz 5ur ’.eiitliJ. .itI S

  8. Alphabetic List of all DoD Prime Contractors, FY 88.

    DTIC Science & Technology

    1988-01-01

    V) oo o 2 ___ m__ 0 I)u00 9H %I EI uE48Z MOD Z ) 01 § 1 Cc U., P 0 0) 4 C) I-I 0 I’-4 CO ECC 2-40 0020402 ") z 44I ൹--4- 01N2 0 1U-4Z 9- I -X0: l 40...2 IL 0 lot 9-40~"" no HOMO - 200 -~oH 4 0 IZS’ 00 2 z~0sS0 0- 00 QI4I m 0 ’C a~09 40Q t 8 014 to 0 I.4V 8 , N 1 0 .49-49-8 - 00 01-04 o1-4 4 u 0 0

  9. Fundamentals of Acoustic Backscatter Imagery

    DTIC Science & Technology

    2011-09-20

    pressure, I,, of 1 /iPa, corresponds to 0.67 x 10- 8 Wim2. Assuming spherical spreading, the one meter distance reference frame, and the definition of dB (Eq...then be approximated by an infinite series Fundamentals ofAcoustic Backscatter Imagery 11 W(r) = Wm (r) + X Fjsc (r) j=O where "tic(r) is the incident...f( x ,y, Z)Iz=h(xy) = 0 f( x , y, z)I z=h( x ,y)= f( x , y, Z) I z o + h di+ h 2 d2f +zz z= The function ftx,y,z) can represent, for example, the stress

  10. Word Criticality Analysis. MOS: 57H. Skill Levels 1 & 2.

    DTIC Science & Technology

    1981-09-01

    CATIIEE C -3-12,6 3-- 10. C 3 - 13,4 - -I CALlIt0 1- 96,1 3- S,1 1- 96,1 1 97T1 I’) I LHIAFING 3- 5, 1 1.- 2Ct .,1 3-205,1 1- 93,1 I- 66,1 I CHIN 3-169,Z 3...1- 16,1 1- 1.5 34- I3,5 1- 61t.1 3 ".1 q 70. 3 71.l .11 F4NDL(R ŗ- 20,1 I tD R 3-I79i1 I 3-177,1 -%- 17F. 3-17501 -172i2 IZ�,1 -170.1 1-169i1 I

  11. A Study of Model Based Maneuvering Controls for Autonomous Underwater Vehicles

    DTIC Science & Technology

    1987-12-01

    y - IX)pq - IXY(p2 -q2 ) - Iz(pr+q) + Ixz(qr-j) + m[XQ(v + ur - wp) -yG(u - r + wq)J 15[(N p + Njrr+Npq pq + Nqr qr Z4[.$Ný v + Nj up + Ný ur + N’q vq...MRR = MWDOT= MQ- ,MVP = MVR = MW = , MV ,MDS = ,MDB = MQN ,MWN = ,MDSN= * YAW HYDRODYNAMIC COEFFICIENTS CONST NPD*T= , NRDOT= NPQ NQR NVDOT= , = ,NR...XG*WO+... A(,)=RHO/2*L**5*NP8*QO + RH/**4JPU+W*OW+. A(65)= IY*PO + IX*PO - 2*IXY*QO - X O+ !4ASS*Y RHO/2*L**5* (NPQ*PO+ NQR *RO) + RHO/2 *L**4*N)Q*VO A

  12. [Clinical problems in medical mycology: Problem number 50].

    PubMed

    Walker, Laura Guadalupe; Arechavala, Alicia; Messina, Fernando; Negroni, Ricardo; Santiso, Gabriela

    We present the case of a 34 year-old man, HIV-positive, who had suffered a disseminated histoplasmosis treated with amphotericin B one year before his admission. He was admitted at the Infectious Diseases Muñiz Hospital with a non-lithiasic chlolecystitis. During the clinical examination perigenital skin lesions compatible with tinea cruris, as well as proximal subungual onychomycoses of toenails, were observed. Microsporum gypseum was isolated from both types of lesions. Oral terbinafine led to a good clinical response. Treatment prescription was a big challenge in this patient because he was receiving HAART and itraconazole, and there was scarce experience in the treatment of nail infections due to M. gypseum.

  13. [Clinical problems in medical mycology: Problem number 47].

    PubMed

    Corti, Marcelo; Muzzio, Estela; Villafañe, María Florencia; Priarone, María Marta; Messina, Fernando; Arechavala, Alicia; Maiolo, Elena; Negroni, Ricardo; Franze, Oscar

    2013-01-01

    A 66 year-old man, who had lived in Paraguay and was a rural worker, was admitted to Infectious Diseases Hospital F. J. Muñiz in Buenos Aires. He presented fever, loss of body weight, cough, mucopurulent expectoration, wide perianal ulceration, paresthesia and paresis of both legs as well as vesical and anal sphincter dysfunction. He was a heavy smoker and drinker. Thorax X-ray examination showed bilateral micronodular interstitial lesions. With a NMR of the dorsolumbar spine region a nodular lesion outside the spinal cord (which produced compression of this organ) was shown. The diagnosis of disseminated paracoccidiodomycosis was based on the finding of Paracoccidioides brasiliensis in the skin ulcer in histopathology and mycology studies, and on the positive results of serologic tests with paracoccidioidin antigen. The patient was treated with trimethoprim-sulfamethoxazole with good clinical outcome.

  14. Public Works Center Pearl Harbor Fleet Moorings Underwater Inspection Report.

    DTIC Science & Technology

    1983-09-01

    CHESNAVFACENGCOM REPORT FPO-1-83, "PWC PEARL HARBOR FLEET MOORINGS INSPECTION REPORT... -’..-.-..;-.-. . s,’. v V’* vi. 0.0 o 4. t!J IA -0 iiiA a𔃼 𔃺’ CL :2I...8217 . . 7 - - - -- - - ". iA Avi << o, .t2.% -AAl ZLI. ,1* . . . . . . . . 4 vi * U)A 0 a 7 -uj z .13 Zn x- -I-z 0 z d= -3 I =- I u2 (N N I...I * * J .p II VI%’ I1. IA IIIq 9> <-- - - - - - - - - - _us: * > 13 Z - - - -A- - zz C6 aa wi a 06 > cc - - _=j = - =Il p 2 Z

  15. Segmentation and Analysis of Stereophotometric Body Surface Data.

    DTIC Science & Technology

    1982-04-01

    Pzem SMU Md deodw". ia tan bovulumla, ad bcu 2. beaM .. WMm euspood to on axis Sysem I& Wic he o ae&NU A Iis Me* $10"sa 210t, ie T axis Points to the...34 0A 0 N F. 9% t% P *C0 NPN NU W x 0 H Ow .4NO P - - J f m * E- 0 0 0 L4I* Q A’ PP C IA IA C 00-0- 0 k4 3* ~* E-4 t Z QUnat &, tPP . M 4 IN.l IA 1 w P i...ORIGINAL MATRIX. DO 18 1:1,3 DO 5 J:1,3 5 A(I,): TEN(NOSEI,J) 10 CONTINUE N: 3 MM: 3 IA : 3 IZ: 3 - BALANCE MATRIX A PRIOR TO EIGENVALUE COMPUTATIONS CALL

  16. Burlington IAP, Vermont. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

    DTIC Science & Technology

    1981-12-23

    PARTS A - F POR FRU HOUWiL OBS: JUN 73 - MAY 81 POW FROM DAL! OBS: JAN 48 - -AT 81 TDI CO VERSION GM TO LST: - 5 DCC 2 3 ISeI ’ ,IS TlO( lw.-. Tt REEN...13Z 8.3 5.1 13.3 7.44 ,1-2’ 1i.Z 1.2 12.I t ,5 3.4 11.2 74 TOTALS 11 2.2. 0 13o8 1O.i 3.1 .0 12.6 551 .GIAL 4TA ’CCODEO IN SYNOPTIC COED " USAMAC polo 0...VARS J ~~~AMOUNTS ,INCHS, IIN __RCENT, TOTAL MONTHLY AMOUNTS PIRCeP MOE ACE 1 01 02. 05 .06.10 j.11-25 26.350 .51-1.0 1.01 2.50 25315300 3101-100 co

  17. Installation Restoration Program. Remedial Investigation Report. Minnesota Air National Guard Base Duluth International Airport, Duluth, Minnesota. Volume 3

    DTIC Science & Technology

    1990-01-01

    TENTATIVELY’IDENTIFIED- COMPOUND’ J6b-No.: 6RO01 Work-Order No.: 1055 ,Matrix: Water Conc Unit: ug/ . . Client: ES Oak Ridge Lab Sample ID: ;88092770 -BN Attn: Bili ...8217. 759 V 8 80 ’" 70 ’.0 50 100 150 204 50 300 351 400 450 500 f ile: )00OU0 Scan 1: 351 Retn. tine: 4.8 nlz Int. m!z Int. mlz Int. mlz Int. mIz Int, V...100 6 1 .296 139.20 6.268 213.05 . 351 276.10 3. 383.50 .501 62 . .230 150.20 1.264 203.25 .650 27.00 1.789 389.10 .12 7.00 2.953 139.20 3.137 217.05

  18. Significance of symmetry in the nuclear spin Hamiltonian for efficient heteronuclear dipolar decoupling in solid-state NMR: A Floquet description of supercycled rCW schemes

    NASA Astrophysics Data System (ADS)

    Equbal, Asif; Shankar, Ravi; Leskes, Michal; Vega, Shimon; Nielsen, Niels Chr.; Madhu, P. K.

    2017-03-01

    Symmetry plays an important role in the retention or annihilation of a desired interaction Hamiltonian in NMR experiments. Here, we explore the role of symmetry in the radio-frequency interaction frame Hamiltonian of the refocused-continuous-wave (rCW) pulse scheme that leads to efficient 1H heteronuclear decoupling in solid-state NMR. It is demonstrated that anti-periodic symmetry of single-spin operators (Ix, Iy, Iz) in the interaction frame can lead to complete annihilation of the 1H-1H homonuclear dipolar coupling effects that induce line broadening in solid-state NMR experiments. This symmetry also plays a critical role in cancelling or minimizing the effect of 1H chemical-shift anisotropy in the effective Hamiltonian. An analytical description based on Floquet theory is presented here along with experimental evidences to understand the decoupling efficiency of supercycled (concatenated) rCW scheme.

  19. Fixed-Cone Valves, New Melones Dam, California. Hydraulic Model Investigation.

    DTIC Science & Technology

    1981-04-01

    The discharge coefficient C in the equation, Q = CA 2 gH where Q = discharge, cfs A = area of conduit immediately upstream of valve, ft2 g...27.7 in. Sleeve Travel = 20.2 in. Sleeve Travel = 1.2 in. Sleeve Travel = 9.7 in. No. = 1730 cfs q = 1590 Cf Q = 1340 cfs Q = 1050 efs 500 127.0...4 z 0 CD, z w w iz 0 w -i LU mt IJJ 0 LU toooz > z L 0 LU ww z 00c 0 uLU > - > >i uj PLATE 5 00 _ _ _~II ___ _ 8 0 0. 0 IAJ z ____ 0 L Q -LJ &hJ ICl

  20. Ring State for Single Transition Metal Atoms on Boron Nitride on Rh(111)

    NASA Astrophysics Data System (ADS)

    Natterer, Fabian Donat; Patthey, François; Brune, Harald

    2012-08-01

    The low-temperature adsorption of isolated transition metal adatoms (Mn, Co, and Fe) onto hexagonal boron nitride monolayers on Rh(111) creates a bistable adsorption complex. The first state considerably weakens the hexagonal boron nitride- (h-BN-) substrate bond for 60 BN unit cells, leading to a highly symmetric ring in STM images, while the second state is imaged as a conventional adatom and leaves the BN-substrate interaction intact. We demonstrate reversible switching between the two states and, thus, controlled pinning and unpinning of the h-BN layer from the metal substrate. I(z) and dln⁡I/dz curves are used to reveal the BN deformation in the ring state.

  1. Dollar Summary of Federal Supply Classification and Service Category by Company, FY 85. Part 10 (7035-9150).

    DTIC Science & Technology

    1985-01-01

    SiONSORiNG 3b OFFICE SYMBOL 9. PROCUREMENT INSTRUMENT IDENTIFICATION NUMBER (If applicable) i"i ’ y , 51te, and ZIP Code) 10 SOURCE OF FUNDING NUMBERS...0 0 w lee a 0 w * aF a w Y c z Z) 4 <ac z z<Ze a 44 1 lI4 le.- oeel0 lee.-I. 0eelLA Veel I-V 1 e . . leeto c c -. c 44 dc a1 al aL I0c lee C .40U 1...4 Co 4 a a 0a ma 0 z a4mC o~ ~ . I-- I. <-m I-- wn a n a n a n a n annwn a a n a n a-~ y - I-Z aaa a. a a . a. a .- a. a. a. m~a a . a . a . a ma -C

  2. Installation Restoration Program. Phase 1. Records Search. Buckley Air National Guard Base Aurora, Colorado

    DTIC Science & Technology

    1982-08-31

    area to another. 3-5 0L 2tl c tC - 4- CC, - a 4- 0 SA7 04ID3 .0 O z = 4-c C cCL ~ 0 C Z-c 4- -~, 19,; OI + =V). c -- mC~ 0. O 1 144- - cO *00 04-04- V...we cc -L O = bLLC~ U C L C- Cc L- Cc4- 0- Le-t A C3 C C COUC C -- 0U v -- 0 C2L L E= CLE o ~ 4-CU bC 4- 5 e -4 -~~0 4-t 4- C b b m2 C2T 4-C C - ~ C iz... o

  3. Meteorological Influences on Smoke/Obscurant Effectiveness. Phase 2. Volume 1

    DTIC Science & Technology

    1991-11-01

    I I I 1 Iz 0 00.. 0U CI III I I I 4II’ I- .- 0 .00 Q 0o F.0.1-2 es~mn gi o deelpen ts I f 9m pra 0-0 000 a C 0 I 0 0 0. 0I 0 00 0 0 0 I 0- V to Ci uj...0Lni 0 - 10-24 -4 > 00 Q 03 L. to 41 0 0 . - 0 - au I. L.. O ~ . al 41 Cu .0 000 ’o 1% mu ti, 0. 00% U~c -1. f 04o 02c c 00 N L. 6.- o* ~ . 01 0 - 0 -0...ecological models," Methodology In Systems Modeling and Simulation. (B.P. Zeigler, M.S. Elzas , G.J. Klir and T.I. Oren, eds.), North Holland Publishing Co

  4. Subharmonic Solutions Near an Equilibrium Point for Hamiltonian Systems

    DTIC Science & Technology

    1989-04-01

    Thus A = 0 will be continued as A,(6) = A+ + ... j = 1,2. (2.5) Since the matrix V is invertible, W is nilpotent and, V and W commute, the matrix (eV...Hamiltonian system z JA(t)z + JHt..(z, t) where A(t) is a matrix , fl,(z,t) = o(I z 1) and both A and H are periodic in t. On the linear part of the system we...write the Hamiltonian as H(z, t) = 1(A(t)z, z) + II(z, t) (0.2) where A(t) denotes the Hessian matrix of H at z = 0 and ft(z, t) = o(Iz12) represents the

  5. Self-Healing Coatings with Multi-Level Protection Based on Active Nanocontainers

    DTIC Science & Technology

    2009-02-01

    of the coating functionalities due to a real healing of the defect retrieving initial coating integrity •R.S. Trask, G.J. Williams, I.P.Bond, J. R...polyelectrolyte nanocontainers for inhibitor encapsulation 0 1 2 3 4 5 70 80 90 100 SiO 2 / PEI SiO 2 a v . p a rt ic le s iz e , n m Layer number...SiO 2 / PEI /PSS SiO 2 / PEI /PSS/BT SiO 2 / PEI /PSS/BT/PSS/BT SiO 2 / PEI /PSS/BT/PSS Layer by Layer assembling process M.L.Zheludkevich, D.G.Shchukin

  6. Heat Transfer Testing in the NSWC Hypervelocity Wind Tunnel Utilizing Co-Axial Surface Thermocouples

    DTIC Science & Technology

    1980-03-19

    8217 DT L FILE COPY I NSWC MP 80-151 AD- A225 273 HEAT TRANSFER TESTING IN THE NSWC HYPERVELOCITY WIND TUNNEL UTILIZING I CO-AXIAL SURFACE...ui - z Ur) 2 MIT- UA U*) C> In> (NJ 01 0017 20 U NSWC MP 80-151 Iz It c 06I- U) zII 00a Lii Vl 0 1 2 - cr > zI 0 z U-- 01 OT ’O _ _ _~i 01 01 NSWC MP...CS.LN’X -- - - - -jJ -f- - - - Z r- - - ~ ~ - -- 4 I ------ ----- ----- ----------------------------------- V n A j) r A r% Cr r, -r n rO A r. A A C

  7. Comparison of Transition Metal-Mediated Oxidation Reactions of Guanine in Nucleoside and Single-Stranded Oligodeoxynucleotide Contexts.

    PubMed

    Ghude, Pranjali; Schallenberger, Mark A; Fleming, Aaron M; Muller, James G; Burrows, Cynthia J

    2011-04-15

    As the most readily oxidized of DNA's four natural bases, guanine is a prime target for attack by reactive oxygen species (ROS) and transition metal-mediated oxidants. The oxidation products of a modified guanosine nucleoside and of a single-stranded oligodeoxynucleotide, 5'-d(TTTTTTTGTTTTTTT)-3' have been studied using oxidants that include Co(II), Ni(II), and Ir(IV) compounds as well as photochemically generated oxidants such as sulphate radical, electron-transfer agents (riboflavin) and singlet oxygen. The oxidized lesions formed include spiroiminodihydantoin (Sp), guanidinohydantoin (Gh), imidazolone (Iz), oxazolone (Z) and 5-carboxamido-5-formamido-2-iminohydantion (2-Ih) nucleosides with a high degree of dependence on the exact oxidation system employed. Interestingly, a nickel(II) macrocyclic complex in conjunction with KHSO(5) leads to the recently reported 2-Ih heterocycle as the major product in both the nucleoside and oligonucleotide contexts.

  8. Size Distributions of Solar Flares and Solar Energetic Particle Events (POSTPRINT)

    DTIC Science & Technology

    2012-09-20

    Letters, 756:L29 (4pp), 2012 September 10 Cliver et al. −5 −4 − 3 −2 2 3 4 5 6 7 8 lo g( N o. o f F la re s/ B in S iz e) M X X10 X100 1 log (SXR...1– 8 Å fluxes of SXR flares associated with >10 MeV proton events with peak fluxes 1 pfu (light blue line); ( 3 ) peak 1– 8 Å fluxes of SXR flares...Table 2); ( 3 ) the peak 1– 8 Å fluxes of 59 SXR flares associated with CMEs with speeds 1000 km s−1 (red line; Yashiro et al. 2006); and (4) the peak

  9. Machine Learning Search for Gamma-Ray Burst Afterglows in Optical Images

    NASA Astrophysics Data System (ADS)

    Topinka, M.

    2016-06-01

    Thanks to the advances in robotic telescopes, time domain astronomy leads to a large number of transient events detected in images every night. Data mining and machine learning tools used for object classification are presented. The goal is to automatically classify transient events for both further follow-up by a larger telescope and for statistical studies of transient events. Special attention is given to the identification of gamma-ray burst afterglows. Machine learning techniques are used to identify GROND gamma-ray burst afterglow among the astrophysical objects present in the SDSS archival images based on the g'-r', r'-i' and i'-z' color indices. The performance of the support vector machine, random forest and neural network algorithms is compared. A joint meta-classifier, built on top of the individual classifiers, can identify GRB afterglows with the overall accuracy of ≳ 90%.

  10. Color-density relation in the LOW Z sample of the SDSS DR10

    NASA Astrophysics Data System (ADS)

    Deng, X. F.

    2015-04-01

    The aim of this study is to examine the environmental dependence of the u-r, u-g, g-r, r-i and i-z colors in the loz z sample of the Sloan Digital Sky Survey Data Release 10 (SDSS DR10). To decrease the radial selection effect, I divide the low z sample into subsamples with a redshift binning size of Δz=0.01 and analyze the environmental dependence of colors for these subsamples in each redshift bin. The statistical results show that all five colors of galaxies in the low z sample are weakly correlated with the local environment, which is consistent with the results of main galaxies at z>0.15 and CMASS galaxies.

  11. Worldwide Report, Arms Control.

    DTIC Science & Technology

    2007-11-02

    will regulating th7 nonprolifSon ofIZ^^ ° f the international system of ovurcort~^ ?it^.^.Xl^uoS^^tT^*"^ t0 PlaCe «"" IAEA...DromLf*™Cle!? «*ivlty in our country will, monitoring by this 1^^"^ ° f ^ ■»<" ° f ä^I^t^irTl^JJr ""V* inst"utions of IAEA are situated, the...agency for the purpose of’workTn* f ^A**10ŗ between the USSR and governing7 IAEA guarantees wit^re^ecf t’o o^rt ^"A0" ° f "" agreement activity in

  12. Significance of symmetry in the nuclear spin Hamiltonian for efficient heteronuclear dipolar decoupling in solid-state NMR: A Floquet description of supercycled rCW schemes.

    PubMed

    Equbal, Asif; Shankar, Ravi; Leskes, Michal; Vega, Shimon; Nielsen, Niels Chr; Madhu, P K

    2017-03-14

    Symmetry plays an important role in the retention or annihilation of a desired interaction Hamiltonian in NMR experiments. Here, we explore the role of symmetry in the radio-frequency interaction frame Hamiltonian of the refocused-continuous-wave (rCW) pulse scheme that leads to efficient (1)H heteronuclear decoupling in solid-state NMR. It is demonstrated that anti-periodic symmetry of single-spin operators (Ix, Iy, Iz) in the interaction frame can lead to complete annihilation of the (1)H-(1)H homonuclear dipolar coupling effects that induce line broadening in solid-state NMR experiments. This symmetry also plays a critical role in cancelling or minimizing the effect of (1)H chemical-shift anisotropy in the effective Hamiltonian. An analytical description based on Floquet theory is presented here along with experimental evidences to understand the decoupling efficiency of supercycled (concatenated) rCW scheme.

  13. Metamaterial and Metastructural Architectures for Novel C4ISR Devices and Sensors

    DTIC Science & Technology

    2015-03-01

    to measure propagation loss. We used an external-cavity laser, tunable between the wavelengths of 1535 and 1575 nm. We split the beam from the laser...Average propagation loss curve for our waveguide 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 1535 1545 1555 1565 1575 N o rm al iz e d p o w e r (A U...Wavelength (nm) 1.169 cm .867 cm .475 cm 0 1 2 3 4 5 6 1535 1545 1555 1565 1575 A ve ra ge lo ss ( d b /c m ) Wavelength (nm) 15 2.5.3 Group Velocity

  14. 20301A Assault Breaker, Missile Number FTV-1, Round Number VIGI, 31 March 1981.

    DTIC Science & Technology

    1981-03-01

    W -C D00F ~ * N N - i n- l- CFr vv r .% r , -4I P - O l ’ 0D -q : z I OC4 c C n% Yf)W lC F 0N6 0N% CP LA AC VC ~ r)p)W ni) v4 t ,k nU ) L C10I 0P .P oa...LAi -. P-% ’n-409D? -P)- P nP - 1P n0 n - 1C l l \\ 44 D- CC CI oWC of -f.r ," . 01 01 D1 0% n6 nu ) L A0e I-Z I0L 0 - L&1 *4 * * * .4 NN UN’ in-. 0 W~f

  15. 3D analysis of posturo-kinetic coordination associated with a climbing task in children and teenagers.

    PubMed

    Testa, M; Martin, L; Debû, B

    2003-01-09

    The aim of this study was to characterize the modifications of the posturo-kinetic coordination during a climbing task as a function of postural and/or movement constraints in children (8-10 years) and adolescents (10-15 years). A 3D-analysis of forces was recorded for different movement amplitudes and types of holds. The results show the involvement of horizontal and vertical forces to maintain equilibrium during the steady state changes for different experimental groups. The contribution of horizontal and vertical forces changes in the course of movement realization. The vertical momentum (Iz) is mainly involved in the movement initiation: this role is mostly meaning for children. The horizontal momentum (Ih) is mainly involved in controlling equilibrium: this role is mostly meaning for adolescents.

  16. Development of an Advanced Continuum Theory for Composite Laminates. Volume 1

    DTIC Science & Technology

    1993-12-31

    a2Ul -iz a2 0 () 2 ~1 = au au T912 +ea3 (o ae)12~~o e 3 1 -* a 1 aOu1 3? ON I 2 N2a a a2u allU 1 U -1 (4.58) 3 ,e2 91 2 C +57-) 2i aLu3 - -2 0 -1a2au12...a ia g 2 K12 3 Cl, =- •L, ) , )+z -= a2% & r a(z7T) 2I K2 a = ( ±!I + Z= r a o-r r c -a IK2 eU2 naUII eU3 U 2rOV _31 T ,- 1- 0 II aza I Car, I The

  17. Charge Transfer Between Quantum Dots and Peptide-Coupled Redox Complexes

    DTIC Science & Technology

    2009-01-01

    scale ) Ruthenium complex 190 2009 NRL REVIEW NANOSCIENCE TECHNOLOGY N or m al iz ed C ur re nt (µ A ) Potential, V vs...DHLA QDs Abs 2 Ru /QD Abs 5 Ru /QD FIGURE 4 Enzymatic assay of chymotrypsin activity utilizing QD–Ru peptide conjugates, showing enzymatic ve ...0.01 0.02 0.03 0.04 Vmax = 0.04 +/- 0.02 µM/min KM = 0.83 +/- 0.16 µM KM = 2.2 +/- 0.5 µM Vmax = 0.01 +/- 0.004 µM/min No inhibitor + Chymostatin inhibitor V el oc ity (µ M C hy m -R u cl ea ve d

  18. Mid-Infrared Variability of Our New Nearby Neighbor

    NASA Astrophysics Data System (ADS)

    Radigan, Jacqueline; Buenzli, Esther; Apai, Daniel; Cowan, Nicholas; Burgasser, Adam; Triaud, Amaury; Gillon, Michael; Faherty, Jacqueline; Plachvan, Peter; Beletsky, Yuri; Morrell, Nidia

    2013-10-01

    Recently, the discovery of a brown dwarf binary only 2 parsecs from the sun was announced, making it our 3rd closest neighbor after Alpha-Centauri and Barnard's star (Luhman et al. 2013). Incredibly, large-amplitude variability (11% in an i+z filter) was announced for the secondary ~T0 component shortly after (Gillon et al. 2013), indicative of patchy clouds. Here we propose to obtain time series observations of this benchmark system with Spitzer to probe cloud structure in its upper atmosphere. As the only brown dwarf system whose mass can be independently constrained from an orbital measurement, and whose 3D clouds structure can be probed from time-domain studies, the Luhman 16 system provides singular opportunity to investigate the sensitive dependence of cloud structure at the L/T transition on effective temperature and surface gravity.

  19. Technology Insertion-Engineering Services Process Characterization. Task Order No. 1. Book 3 of 3. Database Documentation Book. OO-ALC MANPGW (Brakes - Profiles)

    DTIC Science & Technology

    1989-12-15

    l 17%’ if- I- 0 L1L1 -I I I -1--- 00 U)) co 4Z0 J I cc I I IK IL I I IL I - - - I 0 I I I I- I I -I alI I l ol : IZ ICA a .~ I MEI I 0~ .~ I I 0-I ImeI...DRILL AND TAP OLE . 5250W .1525 0020 E RJP-PW-R1 1.00 REM RPI. PAPRWRK SIGN OFF DOC .01001 .010 9000 JA 01 00 .00 LABOR STANDRD HISTORY .000 .000 .000...CLEANED A-ND PROTECTE:’i (C/P MOVE) FOR __________ MOVES BETWIEEN O.-PERA-T :OEN/D:. ESPA *T(H _____ _____ ______ STA1T IONS. :~ 4::: 4 :::: . . *W A

  20. Three-Dimensional Material Properties of Composites with S2-Glass Fibers or Ductile Hybrid Fabric

    DTIC Science & Technology

    2013-01-13

    5 Figure ence of mat n PU Renca s of 2.81 cm s of 2.54 cm shows all n hat materia ar strength 0.8 0.9 1 1.1 1.2 N or m al iz ed St re ng th R es...and 1.91 .). ormalized l thickness d modulus for 3.81 c Value = 3.27 @ Value = 2.91 @ Materia m retrieved not a criti -of-plane st ied the out...h of Materia rocedure is gth (SC-15 ested at 21 strengths of results of M r to the resu terial 5, and tiffness resu low for an 1.91 cm y Sxy SCx

  1. Prime Contract Awards by $100,000 or More by Federal Supply Classification or Service Category and Purchasing Office. Part 2 (5810 Communications Security Equip and Comps 9999Misc Items)

    DTIC Science & Technology

    1990-01-01

    ZOO XZ0.000O. Z 00 03 .L WO La. OS-4 .0.0..La. 00 L. r4 - 0 4444444ZZZZZZZZZZZZZZZZZZZZZzzz4- ode (0j w0 04 qr L Z40 (D4 "o - wo...zj in C- 1.4 TM 30 40 UO - C . (4 C.) 0a 0 040 In In . I (A LAJ 0or- a W-o CM C -U) _iz Ř CV)C4I’- V 4Ci U 4 0 C4 C0 U)o MU 1 0 up >0 0.9 Porn 0* i...10 "- 000N0 CV 4 Un In In (D InU w 0). 1 1-. 04 z 0 C1 -4 C U) 0 4 00 >0 4 0 <- e wn l ~ 00 30. Go- 40 UCM m 0 C L U. L aoX 0 L . d 40006 o Zoo

  2. Development of a Computer Emission Inventory Routine for Aircraft Ground Support Equipment. Volume II. Appendices.

    DTIC Science & Technology

    1981-09-30

    MA 0 CC X AWAA Aws AC VI S M C. A A ZZ 17WC c-uuti 0 Goo*6V* *6664*** NL aal 0 4NT 4wI usuu HL V4 OCNUVIw v 4 %AWOi& Z S1CUESSSSZUW U 18 K.~C cu .d 0i...I 25 0*M*(U* *0* *. m.4 . 4*4 .4 c*V0*Q**rI * * ** * Z 0.L)C w i T- vi Iz I 26 QM V )) cu CC U ox 0 oc dw CC % U 4I V) V) V Ii. ML~27 OD * D *D D * D...G IIc IX XvEEEEI- Z 29 m D D(9c Iwwo MsM4Aseesr4 essnc lu C =0 L I- U. H v4 v4 A4OJ vit 03 ( * * * * *e* *D * *N* * * IL1) W * ** OD* E( ata C S N

  3. UVR-induced G-C to C-G transversions from oxidative DNA damage.

    PubMed

    Kino, Katsuhito; Sugiyama, Hiroshi

    2005-04-01

    Many oxidizing agents induce G-C to T-A and G-C to C-G transversions, and the frequency largely depends on the oxidative conditions. Guanine is the most oxidizable base among natural bases. The typical oxidative lesion product 8-oxoguanine (8-oxoG) is responsible for G-C to T-A transversion but not for G-C to C-G transversion, and 8-oxoG is more readily oxidized than guanine because of its lowered ionization potential. Recently, imidazolone (Iz), guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) have been demonstrated as oxidative lesion products of guanine and 8-oxoG, which could be responsible for G-C to C-G transversions by forming specific base pair formations.

  4. Prime Contract Awards by State or Country, Place and Contractor. Part 16 (Fort Hill, Virginia - Chesapeake, Virginia), FY1991

    DTIC Science & Technology

    1991-01-01

    N4 NNN N) N* 4 I4 Uro -4 c" iz If 0)0 In( aI o 0 ~ 0 - o,’ InI m 10 040 0 C)()-0 04 r- -44- P-2 CO-4c, 00 ) C 40 C44 4 0 > C4 444 4 10 I, C I M0-4 040...4w0O"sO0 -a m n 0I--, A0 w n 44O. -0 0 - - qt U)n-(0COU)-- o)4 of0) 1 00 I moo( ON000N hO4(C(( (0 1- In IsLA (0000ULf :, 4i u I 0000 I- Nf (0(0

  5. Battlefield Maintenance and Recovery Module for the Airland Research Model.

    DTIC Science & Technology

    1986-03-01

    8217-’- I -I0 =)13 - E4 z : C) m Ezw 14)W r-4 OE-4 E-1E-W =3: 11 1311 n 4J -4 E-’ Wz 14+ 0i20- - -W-E-4 on - -iz WH 4~~ L"O E-4- t40z0++1 - 10 f) WM::zW0...16 ES- 4-P-1- +4 + I - 3 0 0 1 0 0 -0 4- ii a4 - 04 - a4Z -N.~ 1- C4 13:11 3: kZI 3 EI- o3 0 P- I ZW I - ~ - - - 4 3I P I EZW I HN-N N N-N 44tI -I

  6. USAF Bioenvironmental Noise Data Handbook. Volume 5. MA-1A Power Unit, Gas Turbine Engine (Continental)

    DTIC Science & Technology

    1975-06-01

    w =jI Wo I~t to - I 0 I I DM Z IWI Ui J Ito 00 I =I-4 CI EZW 1 I O tco 1-44 -- Zu lit 41L5 I 0 - -------- -- - -.------------ --- N I I 1 0 I 1 cm I...Z Z Ci i BIi 1D 4 -j 0 BC’) B1 BB -’ 4 H BM BW4 B -0. I I) w ~ U B3 U BI Be IBI.- H I I L A . B0- B CUL B! I IJ ( Il- 1 ) 4 W I I I C B 1~ BC BB )- 3...w.4 I t i I I LL. LL II. C I~~~~~ . c.CCC L!~ II’ W 0 1D C * 1 TL 1it .. . ... . . ... ............ I’ C It I1 .e ’I ’ e c .- c e c c c4. * c * 3 3

  7. Pulse Shaping and Energy Storage Capabilities of Angularly-Multiplexed KrF Laser Fusion Drivers

    DTIC Science & Technology

    2009-01-01

    the laser cell, including the e-beam pump configuration. Four sets of opposing e-beams are injected by two cathode pairs on each side with an axial...profile snapshots (at 150 nsec) of the e-beams, ASE, internal intensities I(z), and effective saturation intensity ISAT. 4P_ `Y]Y`;a( `J [4 F Q ; 0K L X...a(`V4`Y]Y`Y]Y`;a( `J JJ4 PEB (MW/cm3) IASE (MW/cm2) (a) (b) (c) Q#b#!HP"#$% F#0YL5 %F?K\\XF#0f5 J4P4 JP4 4PJ !4J44 Y8., 02+5 Fig. 7: Total

  8. The effects of selected pre-treatments on germination of seeds of Oriental hornbeam (Carpinus orientalis).

    PubMed

    Ozel, Halil Bariş

    2016-07-01

    In the present study, the effect of some pre-treatments implemented on seeds of Oriental hornbeam (Carpinus orientalis), which has wide geographical variation along Turkey on germination percentage values were investigated. For this purpose, 13 different pre-treatments were implemented to seeds obtained from 17 different populations. According to the obtained results (except control seeds), pre-treatments leading to lowest germination percentage value (8.1%) in Oriental hornbeam seeds was PT10: Keeping seeds for 90 min in sulfuric acid, while highest germination percentage (86.58%) has been obtained with pre-treatment PT13: Implementation of 40% dose of Baikal EM1 + Biohoumous mixture to the seeds, while lowest germination percentage (40.50%) was observed on seeds collected from P7 (Bartin-Kozcağiz) population, highest germination percentage was observed in seeds obtained from P17 (Artvin-Hopa) population.

  9. Rip Channels, Megacusps, and Shoreline Change: Measurements and Modeling

    DTIC Science & Technology

    2010-06-01

    viewability. Top panel izΔ : hCu i j⋅ + ⋅ hCv . Second panel: ˆ i ˆhCu hCv j⋅ + ⋅ . Third panel: hCu i hCv j⋅ + ⋅ . Bottom panel: ˆ ˆhCu i hCv j...panel: hCu i hCv j⋅ + ⋅ . Second panel: ˆ ˆhCu i hCv j⋅ + ⋅ . Third panel: xv hC . Bottom panelu i hCv j⋅ + ⋅ : ˆ ˆhCu i hCv j...flow fields as in Fig. 31. Top panel: hCu i hCv j⋅ + ⋅ . Second panel: hCu i hCv j⋅ + ⋅ . Third panel: ˆ ˆhCu i hCv j⋅ + ⋅ . Bottom panel: asym

  10. Fleet Mooring Leg Design Program Documentation. Volume 6. Source Listings: Compound Leg Reverse Solutions and Postprocessor.

    DTIC Science & Technology

    1982-12-01

    call CSSHP * wv-ite(1S,*1 h,v-tot if (dabs(rtot-v-t It epsv-i gato 5555 if (nlit eq 100) stop 110 if (ibis eq @I goto 13SO If ((v-tot-r)*(rS-r) It...fmnal/t2for/csexzl for## subroutine CSEXZl :mplicit integer*2 (N)implicit daub Ie precision fa-z) i n t eer*2 i Ieg , ist inca ncb )nwa pnwb i soI i...130,140,150I icon 110 continue par in( L tab I-z( at I goto 200 00 120 continue par’an(&lab)-zltzI*j Od-3 gato 200 130 continue par an I ib I-( dotoni

  11. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1987. Part 14. Okinawa Kankyo-Pultrusions Corporation.

    DTIC Science & Technology

    1987-01-01

    r--21 Z % o-.-r-t-r-V(0C (IZ 4 ( A 0O 4 C) CD4 a-t z- 4 l ’ -in Z 0 0 0 0 1.1 -oO tic oo1( a I o oO 0 0 0 0~I& 0 0 0 C) (:)4 (0 04 mz CD 0r2 0r...Cd 0 00 ),.蓐 40 -. 4- 400 go -aci (naOA (a 4ajI a-C a-4460o Al 1 W4 0 44 4 00 0o 0 4 3 1a0 0 4 S N𔃻 00 E O O a 00 001-0C4 ODD- 0. ( AulA ~O a

  12. All Prime Contract Awards by State or Country, Place, and Contractor. Part 10 (Croom, Maryland-Mendon, Mass)

    DTIC Science & Technology

    1990-01-01

    C)( 0)4 4D< T0 :34(0 -4444 >-0( Ca-i1cc1 C-4 if400o LA- In 0 01L-00 (02 000 c0 _iZ LL00 C11000 WZ 4< 0 40 ()It4 I-- 0 In N In 0> ( 0>~I 4(1< 10 0n...34-4 N MiniM N-I -c I N II -0 00 -4 -4N cicimcMc(7ci CD ci -40 C, 0ci ONQ - 4-4 INLA.-4 -4 N ci) 171iMci -40 -4 44 II ciOOOOOOOOOOOO ciC0 0)0 C11000

  13. [Disseminated infection due to Penicillium marneffei related to HIV infection: first observation in Argentina].

    PubMed

    Santiso, Gabriela; Chediak, Viviana; Maiolo, Elena; Mujica, María T; San Juan, Jorge; Arechavala, Alicia; Negroni, Ricardo

    2011-01-01

    The first case observed in Argentina of AIDS-related human penicillosis is herein presented. The patient was a six- teen year-old young man coming from a rural area of southern China. He was admitted at the F. J. Muñiz Hospital of Buenos Aires city with severe pneumonia and adult respiratory distress. Penicillium marneffei was isolated from bronchoalveolar lavage fuid and was microscopically observed in a skin cytodiagnosis. P. marneffei identification was confirmed by rRNA amplification and its phenotypic characteristics. The patient suffered an advanced HIV infection and also presented several AIDS-related diseases due to CMV, nosocomial bacterial infections and Pneumocystis jirovecii which led to a fatal outcome.

  14. [Inhibition of NF-kB Activation Decreases Resistance in Acute Myeloid Leukemia Cells to TRAIL-induced Apoptosis in Multicellular Aggregates].

    PubMed

    Fadeev, R S; Solovieva, M E; Slyadovskiy, D A; Zakharov, S G; Fadeeva, I S; Senotov, A S; Golenkov, A K; Akatov, V S

    2015-01-01

    Suppression of resistance in acute myeloid leukemia cells to TRAIL-induced apoptosis in multicellular aggregates, was studied using small molecule inhibitors of the activation of the transcription factor NF-kB - NF-k9 Activation Inhibitor IV and JSH-23 at non-toxic concentrations. NF-kB Activation Inhibitor IV and JSH-23 reduced resistance in the acute myeloid leukemia cells in multicellular aggregates to cytotoxic action of recombinant protein izTRAIL. It is shown that the use of these inhibitors decreased the phosphorylation of the RelA (p65) as a main marker activation of the transcription factor NF-kB. We discuss a possible reason for increasing resistance in acute myeloid leukemia cells to TRAIL-induced apoptosis in multicellular aggregates.

  15. [The biological properties of the HIV isolated from a virus carrier living in the Byelorussian SSR].

    PubMed

    Rytik, P G; van der Groen, G; Eremin, V F; Kolomiets, N D; Popov, S A; Nijs, P; Willems, V; Verkauteren, G; Il'kevich, Iu G; Lemeshko, N N

    1990-01-01

    Biological properties of an AIDS agent first isolated from a native citizen in the USSR are presented. The source of the virus was a young Byelorussian woman who in the near past had had sexual contacts with a citizen from one of the Central Africa countries. The isolate is thought to be of HIV-I type. It replicated perfectly in many continuous lymphocyte lines and had HIV-characteristic morphology. The protein spectrum of the isolate was gp120, gp41, p65/51, p55, p32, p24, p17. Reverse transcriptase activity was detected in the culture fluid of the virus-containing cell cultures. The isolate was designated HIV-IZ.

  16. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 16 (Panhandle Food Sales-Ray Gene Electric Co Inc)

    DTIC Science & Technology

    1990-01-01

    AD-A236 466 1990 ANNUAL PRIME CONTRACTS AWARDS ALPHABETICALLY BY CONTRACTOR, BY STATE OR COUNTRY, AND PLACE. PT-16 (PANHANDLE FOOD SALES-RAY GENE ...4 I-l e~ I 0 MM 0)1 47470:14710) 0) 0) 0) I" gene , I LA 4 00 0) co -4 -FF- F- C (D <r- 0CD I~ gene , U0 -4 0. C4 0> 0D-4-4-40 C> C- N0 -4 (n L-4 cn...LW ,U ’L a) I CIme 𔃺" 0)0)100)0)10)0) (00 0 Ei(Cn" cc cc c c c c c c c c c 410mc’ " ::U. C 001. C00 r-0C0C r00 C w izI0’ M" ~ 000000 , . > .0 000 s-s

  17. Cable Splicing Project/Maintenance Action AFSC 361X1

    DTIC Science & Technology

    1991-01-01

    standards for subordinates 53 D88 Evaluate progress of trainees 53 C55 Evaluate project drawings or specifications 52 25 LU - - K LUJ -x cr O L z nmtjCiCJ...0U co 0 ~ U). m u.. L -a cU+ 0. mL-~ S- 4-- CO x E S- Ln O : .0 0 *- u CL K ~ 0 a> ) C_ UL S.- (v a) nU -r Ln CA CU - S 0.- o ) a 04 0 - W -0 I_- -3...CU U) u cL E- U O D U)c -0 E a) .- (4--C-LA - S- a ) C - U )r - s- UU U 0..a’oIz K CU .- c () LL 0 U - a~ )U 0 . ’-C CU’ca) 4- --=DS- C -- D-C > 4-0

  18. Martin Marietta Airfield, Baltimore, Maryland. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

    DTIC Science & Technology

    1979-08-02

    82 , 882J S2500 45, 71*e 78.4 81.2 R3,’ 63.9 qt 630 83 83 . R3.4 83 83 . 83 . 83 , 63. 8500 46. 740 81 ., 83 . 86. be -86.’ I-s 86. 86. 86. 86...u&IIn 65000__ 7 -3,. 450 43. 09. 75, 80 . 2 2 , 81 $6180 3 3 348 83 . 83 . >I 3500 450 72. 79.1 85. 67. a8 # 8. 88. Be . 88 88 , 668. 8s 885 81A. 3000 2500...iIz $ ,5 ,. 9o 0 7 -,j82 ) j, 82 . 82oS 82,6 A2. 8 8 . 9 920. 8_2 8 2 _ 200 576 7* 779* 81 . 4 e. 83.1

  19. The CMC/3DPNS computer program for prediction of three-dimensional, subsonic, turbulent aerodynamic juncture region flow. Volume 3: Programmers' manual

    NASA Technical Reports Server (NTRS)

    Orzechowski, J. A.

    1982-01-01

    The CMC fluid mechanics program system was developed to transmit the theoretical evolution of finite element numerical solution methodology, applied to nonlinear field problems into a versatile computer code for comprehensive flow field analysis. A detailed view of the code from the standpoint of a computer programmer's use is presented. A system macroflow chart and detailed flow charts of several routines necessary to interact with a theoretican/user to modify the operation of this program are presented. All subroutines and details of usage, primarily for input and output routines are described. Integer and real scalars and a cross reference list denoting subroutine usage for these scalars are outlined. Entry points in dynamic storage vector IZ; the lengths of each vector accompanying the scalar definitions are described. A listing of the routines peculiar to the standard test case and a listing of the input deck and printout for this case are included.

  20. Growth trajectories of the human fetal brain tissues estimated from 3D reconstructed in utero MRI

    PubMed Central

    Scott, Julia A.; Habas, Piotr A.; Kim, Kio; Rajagopalan, Vidya; Hamzelou, Kia S.; Corbett-Detig, James M.; Barkovich, A. James; Glenn, Orit A.; Studholme, Colin

    2012-01-01

    In the latter half of gestation (20 to 40 gestational weeks), human brain growth accelerates in conjunction with cortical folding and the deceleration of ventricular zone progenitor cell proliferation. These processes are reflected in changes in the volume of respective fetal tissue zones. Thus far, growth trajectories of the fetal tissue zones have been extracted primarily from 2D measurements on histological sections and magnetic resonance imaging (MRI). In this study, the volumes of major fetal zones—cortical plate (CP), subplate and intermediate zone (SP+IZ), germinal matrix (GMAT), deep gray nuclei (DG), and ventricles (VENT)—are calculated from automatic segmentation of motion-corrected, 3D reconstructed MRI. We analyzed 48 T2-weighted MRI scans from 39 normally developing fetuses in utero between 20.57 and 31.14 gestational weeks (GW). The supratentorial volume (STV) increased linearly at a rate of 15.22% per week. The SP+IZ (14.75% per week) and DG (15.56% per week) volumes increased at similar rates. The CP increased at a greater relative rate (18.00% per week), while the VENT (9.18% per week) changed more slowly. Therefore, CP increased as a fraction of STV and the VENT fraction declined. The total GMAT volume slightly increased then decreased after 25 GW. We did not detect volumetric sexual dimorphisms or total hemispheric volume asymmetries, which may emerge later in gestation. Further application of the automated fetal brain segmentation to later gestational ages will bridge the gap between volumetric studies of premature brain development and normal brain development in utero. PMID:21530634

  1. Growth trajectories of the human fetal brain tissues estimated from 3D reconstructed in utero MRI.

    PubMed

    Scott, Julia A; Habas, Piotr A; Kim, Kio; Rajagopalan, Vidya; Hamzelou, Kia S; Corbett-Detig, James M; Barkovich, A James; Glenn, Orit A; Studholme, Colin

    2011-08-01

    In the latter half of gestation (20-40 gestational weeks), human brain growth accelerates in conjunction with cortical folding and the deceleration of ventricular zone progenitor cell proliferation. These processes are reflected in changes in the volume of respective fetal tissue zones. Thus far, growth trajectories of the fetal tissue zones have been extracted primarily from 2D measurements on histological sections and magnetic resonance imaging (MRI). In this study, the volumes of major fetal zones-cortical plate (CP), subplate and intermediate zone (SP+IZ), germinal matrix (GMAT), deep gray nuclei (DG), and ventricles (VENT)--are calculated from automatic segmentation of motion-corrected, 3D reconstructed MRI. We analyzed 48 T2-weighted MRI scans from 39 normally developing fetuses in utero between 20.57 and 31.14 gestational weeks (GW). The supratentorial volume (STV) increased linearly at a rate of 15.22% per week. The SP+IZ (14.75% per week) and DG (15.56% per week) volumes increased at similar rates. The CP increased at a greater relative rate (18.00% per week), while the VENT (9.18% per week) changed more slowly. Therefore, CP increased as a fraction of STV and the VENT fraction declined. The total GMAT volume slightly increased then decreased after 25 GW. We did not detect volumetric sexual dimorphisms or total hemispheric volume asymmetries, which may emerge later in gestation. Further application of the automated fetal brain segmentation to later gestational ages will bridge the gap between volumetric studies of premature brain development and normal brain development in utero.

  2. HIGH IONIZATION SPECIES IN THE NEARBY INTERSTELLAR MEDIUM FROM AN EXHAUSTIVE ANALYSIS OF THE IUE INES DATABASE

    SciTech Connect

    Freire Ferrero, R.; Halbwachs, J.-L.; Morales Duran, C.; Cabo Cubeiro, A. M. E-mail: jean-louis.halbwachs@astro.unistra.fr E-mail: amcabo@cab.inta-csic.es

    2012-02-15

    Main-sequence (MS) and giant late-B and early-A type stars are the best targets for searching for nearby interstellar (IS) Si IV and C IV resonance lines because they are not able to produce them, either in atmospheric layers or in their circumstellar environment, and because many stars of these spectral types are nearby and located in the local interstellar medium (LISM). In addition, the use of certain stars hotter than B6 can lead to misinterpretations (e.g., alpha Arae). This work analyzes the reliable Short-Wavelength Prime high-resolution UV spectra of 558 B6-A9 type stars observed by the International Ultraviolet Explorer at distances lower than 400 pc from the Sun. For the first time, this work utilizes the entire INES database to extract stellar and IS information in a systematic way from homogeneous data. Stars were classified into seven groups: normal (MS and subgiant), giant, peculiar, emission line, Algols, pre-main sequence or Herbig Ae/Be, and shell stars. Only 10 normal stars, located beyond 90 pc, show weak Si IV and C IV absorptions and are clustered around the direction of Sco-Cen, while 85 located closer than 90 pc, as well as another 89 beyond 90 pc, do not show any absorptions at all. We conclude that these highly ionized species originate most probably in the LISM, at 90 pc from the Sun, corresponding to the warm interaction zone (IZ), where the expanding Loop I super-shell and the Local Bubble collide. We base our results on a robust statistical analysis of both spectral types and spatial distributions of the different stellar groups we defined. Our estimated column densities N of both ions are similar to those obtained by other authors for distant stars, suggesting that these absorptions concentrate fundamentally in the IZ. A logarithmic correlation between N and the distance D confirms these results.

  3. Chemical Composition and In Vitro Evaluation of Antimicrobial, Antioxidant and Antigerminative Properties of the Seed Oil from the Tunisian Endemic Ferula tunetana Pomel ex Batt.

    PubMed

    Znati, Mansour; Filali, Insaf; Jabrane, Aymen; Casanova, Joseph; Bouajila, Jalloul; Ben Jannet, Hichem

    2017-01-01

    Essential oil of the seeds from the endemic Tunisian plant Ferula tunetana Pomel ex Batt. was analyzed for its chemical composition and screened for its antimicrobial, antioxidant and antigerminative properties. The chemical composition of the isolated oil is reported for the first time. According to the GC/FID, GC/MS and (13) C-NMR analysis results; 18 compounds were identified accounting for 84.6% of the total oil. The chemical composition of this essential oil was characterized by the presence of a high proportion of monoterpene hydrocarbons (77.3%) followed by oxygenated sesquiterpenes (4.1%) and sesquiterpene hydrocarbons (3.2%). α-Pinene (39.8%), β-pinene (11.5%) and (Z)-β-ocimene (7.5%) were the predominant compounds. Moreover, the isolated oil was tested for its antimicrobial activity using the disc-diffusion and the microdilution assays against six Gram-positive and five Gram-negative bacteria as well as towards two Candida species. The isolated oil was tested also for its antioxidant activity against DPPH, ABTS, O2∙ and hydrogen peroxide (H2 O2 ), and for its antigerminative potential. It was found that it exhibited interesting antimicrobial activity against Salmonella typhimurium LT2 DT104 (inhibition zone (IZ) 16.2 ± 1.0 mm) and Bacillus cereus ATCC 14579 (IZ 15.8 ± 1.0 mm). However, it exerted a moderate antioxidant activity against H2 O2 (IC50 78.2 ± 2.98 μg/ml) and towards O2∙ (IC50 89.2 ± 3.82 μg/ml). The antigerminative effect of this oil was also evaluated in this work. Results showed a toxic effect.

  4. Adaptation of all-ceramic fixed partial dentures

    PubMed Central

    Borba, Márcia; Cesar, Paulo F.; Griggs, Jason A.; Della Bona, Álvaro

    2011-01-01

    Objectives To measure the marginal and internal fit of three-unit fixed partial dentures (FPDs) using the micro-CT technique, testing the null hypothesis that there is no difference in the adaptation between the ceramic systems studied. Methods Stainless steel models of prepared abutments were fabricated to design the FPDs. Ten FPDs were produced from each framework ceramic (YZ - Vita In-Ceram YZ and IZ - Vita In-Ceram Zirconia) using CEREC inLab according to the manufacturer instructions. All FPDs were veneered using the recommended porcelain. Each FPD was seated on the original model and scanned using micro-CT. Files were processed using NRecon and CTAn software. Adobe Photoshop and Image J software were used to analyze the cross-sections images. Five measuring locations were used as follows: MG – marginal gap; CA - chamfer area; AW - axial wall; AOT - axio-occlusal transition area; OA - occlusal area. The horizontal marginal discrepancy (HMD) was evaluated in another set of images. Results were statistically analyzed using ANOVA and Tukey tests (α=0.05). Results The mean values for MG, CA, AW, OA and HMD were significantly different for all tested groups (p<0.05). IZ exhibited greater mean values than YZ for all measuring locations except for AW and AOT. OA showed the greatest mean gap values for both ceramic systems. MG and AW mean gap values were low for both systems. Significance The ceramic systems evaluated showed different levels of marginal and internal fit, rejecting the study hypothesis. Yet, both ceramic systems showed clinically acceptable marginal and internal fit. PMID:21920595

  5. Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex.

    PubMed

    Ohshima, Toshio; Hirasawa, Motoyuki; Tabata, Hidenori; Mutoh, Tetsuji; Adachi, Tomoko; Suzuki, Hiromi; Saruta, Keiko; Iwasato, Takuji; Itohara, Shigeyoshi; Hashimoto, Mistuhiro; Nakajima, Kazunori; Ogawa, Masaharu; Kulkarni, Ashok B; Mikoshiba, Katsuhiko

    2007-06-01

    The mammalian cerebral cortex consists of six layers that are generated via coordinated neuronal migration during the embryonic period. Recent studies identified specific phases of radial migration of cortical neurons. After the final division, neurons transform from a multipolar to a bipolar shape within the subventricular zone-intermediate zone (SVZ-IZ) and then migrate along radial glial fibres. Mice lacking Cdk5 exhibit abnormal corticogenesis owing to neuronal migration defects. When we introduced GFP into migrating neurons at E14.5 by in utero electroporation, we observed migrating neurons in wild-type but not in Cdk5(-/-) embryos after 3-4 days. Introduction of the dominant-negative form of Cdk5 into the wild-type migrating neurons confirmed specific impairment of the multipolar-to-bipolar transition within the SVZ-IZ in a cell-autonomous manner. Cortex-specific Cdk5 conditional knockout mice showed inverted layering of the cerebral cortex and the layer V and callosal neurons, but not layer VI neurons, had severely impaired dendritic morphology. The amount of the dendritic protein Map2 was decreased in the cerebral cortex of Cdk5-deficient mice, and the axonal trajectory of cortical neurons within the cortex was also abnormal. These results indicate that Cdk5 is required for proper multipolar-to-bipolar transition, and a deficiency of Cdk5 results in abnormal morphology of pyramidal neurons. In addition, proper radial neuronal migration generates an inside-out pattern of cerebral cortex formation and normal axonal trajectories of cortical pyramidal neurons.

  6. Age-related changes in the inner zone of the adrenal cortex of the rat--a morphologic and biochemical study.

    PubMed

    de Almeida, H; Magalhães, M C; Magalhães, M M

    1998-09-15

    In this work, a correlative morphologic and biochemical study on the effects of ageing on the rat adrenal Inner Zone (IZ) was made. Male Wistar rats were studied at 2, 6, 12, 18 and 24 months. Structural data of Zona Fasciculata (ZF) showed age-related increase in cell volume (P < 0.05), decrease in mitochondria (P < 0.01) and smooth endoplasmic reticulum (SER) volumes, and increase in lipid droplets (P < 0.01) and lipofuscin granules (P < 0.01) volumes. In Zona Reticularis, the main change observed was the increase in lipofuscin granules (P < 0.001). Serum corticosterone from unstimulated rats increased until 12 months but decreased thereafter (P < 0.01), to levels below those from 2-month-old rats. Similarly, plasma adrenocorticotrophic hormone (ACTH) presented a maximum at 12 months, followed by a decrease to levels higher than at 2 months (P < 0.05). In rats injected either with only ACTH or dexamethasone, before ACTH stimulation, corticosterone level had a maximum at 12 months. In aged rats, serum high density lipoprotein (HDL) and adrenal cholesterol ester increased significantly (P < 0.05 and P < 0.01, respectively), whereas adrenal corticosterone decreased. Products of lipid peroxidation, assayed with the thiobarbituric acid reaction and fluorimetry showed an age-related increase (P < 0.05). The age-related decrease in mitochondria and SER volumes is consistent with the decrease of serum corticosterone. The increase in lipid droplet and HDL and the reduction of adrenal corticosterone level correlate with the increase of adrenal cholesterol ester content. These suggest a continued uptake of steroid precursor but a reduced steroid synthesis. On the whole, the data provide evidence for an age-related reduced functional ability of IZ and particularly of ZF.

  7. DNA damage by the sulfate radical anion: hydrogen abstraction from the sugar moiety versus one-electron oxidation of guanine.

    PubMed

    Roginskaya, Marina; Mohseni, Reza; Ampadu-Boateng, Derrick; Razskazovskiy, Yuriy

    2016-07-01

    The products of oxidative damage to double-stranded (ds) DNA initiated by photolytically generated sulfate radical anions SO4(•-) were analyzed using reverse-phase (RP) high-performance liquid chromatography (HPLC). Relative efficiencies of two major pathways were compared: production of 8-oxoguanine (8oxoG) and hydrogen abstraction from the DNA 2-deoxyribose moiety (dR) at C1,' C4,' and C5' positions. The formation of 8oxoG was found to account for 87% of all quantified lesions at low illumination doses. The concentration of 8oxoG quickly reaches a steady state at about one 8oxoG per 100 base pairs due to further oxidation of its products. It was found that another guanine oxidation product identified as 2-amino-5-(2'-alkylamino)-4H-imidazol-4-one (X) was released in significant quantities from its tentative precursor 2-amino-5-[(2'-deoxy-β-d-erythro-pentofuranosyl)amino]-4H-imidazol-4-one (dIz) upon treatment with primary amines in neutral solutions. The linear dose dependence of X release points to the formation of dIz directly from guanine and not through oxidation of 8oxoG. The damage to dR was found to account for about 13% of the total damage, with majority of lesions (33%) originating from the C4' oxidation. The contribution of C1' oxidation also turned out to be significant (17% of all dR damages) despite of the steric problems associated with the abstraction of the C1'-hydrogen. However, no evidence of base-to-sugar free valence transfer as a possible alternative to direct hydrogen abstraction at C1' was found.

  8. Correlating Photoreceptor Mosaic Structure to Clinical Findings in Stargardt Disease

    PubMed Central

    Razeen, Moataz M.; Cooper, Robert F.; Langlo, Christopher S.; Goldberg, Mara R.; Wilk, Melissa A.; Han, Dennis P.; Connor, Thomas B.; Fishman, Gerald A.; Collison, Frederick T.; Sulai, Yusufu N.; Dubra, Alfredo; Carroll, Joseph; Stepien, Kimberly E.

    2016-01-01

    Purpose To demonstrate a method for correlating photoreceptor mosaic structure with optical coherence tomography (OCT) and microperimetry findings in patients with Stargardt disease. Methods A total of 14 patients with clinically diagnosed Stargardt disease were imaged using confocal and split-detection adaptive optics scanning light ophthalmoscopy. Cone photoreceptors were identified manually in a band along the temporal meridian. Resulting values were compared to a normative database (n = 9) to generate cone density deviation (CDD) maps. Manual measurement of outer nuclear layer plus Henle fiber layer (ONL+HFL) thickness was performed, in addition to determination of the presence of ellipsoid zone (EZ) and interdigitation zone (IZ) bands on OCT. These results, along with microperimetry data, were overlaid with the CDD maps. Results Wide variation in foveal structure and CDD maps was seen within this small group. Disruption of ONL+HFL and/or IZ band was seen in all patients, with EZ band preservation in regions with low cone density in 38% of locations analyzed. Normality of retinal lamellar structure on OCT corresponded with cone density and visual function at 50/78 locations analyzed. Outer retinal tubulations containing photoreceptor-like structures were observed in 3 patients. Conclusions The use of CDD color-coded maps enables direct comparison of cone mosaic local density with other measures of retinal structure and function. Larger normative datasets and improved tools for automation of image alignment are needed. Translational Relevance The approach described facilitates comparison of complex multimodal data sets from patients with inherited retinal degeneration, and can be expanded to incorporate other structural imaging or functional testing. PMID:26981328

  9. Multimodal Imaging of Photoreceptor Structure in Choroideremia

    PubMed Central

    Johnson, Ryan D.; Williams, Vesper; Summerfelt, Phyllis; Dubra, Alfredo; Weinberg, David V.; Stepien, Kimberly E.; Fishman, Gerald A.; Carroll, Joseph

    2016-01-01

    Purpose Choroideremia is a progressive X-linked recessive dystrophy, characterized by degeneration of the retinal pigment epithelium (RPE), choroid, choriocapillaris, and photoreceptors. We examined photoreceptor structure in a series of subjects with choroideremia with particular attention to areas bordering atrophic lesions. Methods Twelve males with clinically-diagnosed choroideremia and confirmed hemizygous mutations in the CHM gene were examined. High-resolution images of the retina were obtained using spectral domain optical coherence tomography (SD-OCT) and both confocal and non-confocal split-detector adaptive optics scanning light ophthalmoscope (AOSLO) techniques. Results Eleven CHM gene mutations (3 novel) were identified; three subjects had the same mutation and one subject had two mutations. SD-OCT findings included interdigitation zone (IZ) attenuation or loss in 10/12 subjects, often in areas with intact ellipsoid zones; RPE thinning in all subjects; interlaminar bridges in the imaged areas of 10/12 subjects; and outer retinal tubulations (ORTs) in 10/12 subjects. Only split-detector AOSLO could reliably resolve cones near lesion borders, and such cones were abnormally heterogeneous in morphology, diameter and density. On split-detector imaging, the cone mosaic terminated sharply at lesion borders in 5/5 cases examined. Split-detector imaging detected remnant cone inner segments within ORTs, which were generally contiguous with a central patch of preserved retina. Conclusions Early IZ dropout and RPE thinning on SD-OCT are consistent with previously published results. Evidence of remnant cone inner segments within ORTs and the continuity of the ORTs with preserved retina suggests that these may represent an intermediate state of retinal degeneration prior to complete atrophy. Taken together, these results supports a model of choroideremia in which the RPE degenerates before photoreceptors. PMID:27936069

  10. SPITZER TRANSITS OF THE SUPER-EARTH GJ1214b AND IMPLICATIONS FOR ITS ATMOSPHERE

    SciTech Connect

    Fraine, Jonathan D.; Deming, Drake; Gillon, Michaeel; Jehin, Emmanueel; Demory, Brice-Olivier; Benneke, Bjoern; Seager, Sara; Lewis, Nikole K.; Knutson, Heather; Desert, Jean-Michel

    2013-03-10

    We observed the transiting super-Earth exoplanet GJ1214b using warm Spitzer at 4.5 {mu}m wavelength during a 20 day quasi-continuous sequence in 2011 May. The goals of our long observation were to accurately define the infrared transit radius of this nearby super-Earth, to search for the secondary eclipse, and to search for other transiting planets in the habitable zone of GJ1214. We here report results from the transit monitoring of GJ1214b, including a reanalysis of previous transit observations by Desert et al. In total, we analyze 14 transits of GJ1214b at 4.5 {mu}m, 3 transits at 3.6 {mu}m, and 7 new ground-based transits in the I+z band. Our new Spitzer data by themselves eliminate cloudless solar composition atmospheres for GJ1214b, and methane-rich models from Howe and Burrows. Using our new Spitzer measurements to anchor the observed transit radii of GJ1214b at long wavelengths, and adding new measurements in I+z, we evaluate models from Benneke and Seager and Howe and Burrows using a {chi}{sup 2} analysis. We find that the best-fit model exhibits an increase in transit radius at short wavelengths due to Rayleigh scattering. Pure water atmospheres are also possible. However, a flat line (no atmosphere detected) remains among the best of the statistically acceptable models, and better than pure water atmospheres. We explore the effect of systematic differences among results from different observational groups, and we find that the Howe and Burrows tholin-haze model remains the best fit, even when systematic differences among observers are considered.

  11. The in Vitro Antibacterial Efficacy of Persian Green Tea Extract as an Intracanal Irrigant on Enterococcus faecalis Biofilm

    PubMed Central

    Ramezanali, Fatemeh; Samimi, Shiva; Kharazifard, Mohammadjavad; Afkhami, Farzaneh

    2016-01-01

    Introduction: The aim of this study was to compare the antibacterial effect of Persian green tea extract (GTE) and 2.5% sodium hypochlorite (NaOCl) against Enterococcus faecalis (E. faecalis) as an intracanal irrigant. Methods and Materials: Thirty freshly extracted teeth were instrumented and sectioned into mesial and distal segments. The specimens were put into wells containing 2 mL of E. faecalis-containing medium. After 3 weeks, the specimens were removed and divided randomly into three groups (n=20). Each group was exposed to 3 mL of different irrigants for 3 min. Groups 1, 2 and 3 were irrigated with GTE, 2.5% NaOCl and normal saline, respectively. Biofilm formed in the middle third of the root canal was carved by sterile scalpel and cultured in Mueller-Hinton medium. Number of colony forming units (CFU) was counted on each plate. In addition, antimicrobial activity of the irrigants was evaluated by the agar disc diffusion test. The diameter of inhibition zone (IZ) around each irrigant was evaluated. The Kruskal-Wallis and Dunn tests were used to analysis the data. Results: While in NaOCl group no bacterial colonies were observed, the mean number of E. faecalis in GTE and control groups were 275±74 CFU/mL (P<0.001) and 119×108±11×108 (P<0.001), respectively. The mean of IZ in NaOCl and GTE groups were 24.35±0.78 and 6.9±0.87 mm, in order of appearance (P<0.001). Zone of inhibition was not observed around the control group (P<0.001). Conclusion: This research highlighted the potential role of plant extracts in antimicrobial root canal irrigation protocol. PMID:27790260

  12. Stable large-scale CO2 storage in defiance of an energy system based on renewable energy - Modelling the impact of varying CO2 injection rates on reservoir behavior

    NASA Astrophysics Data System (ADS)

    Bannach, Andreas; Hauer, Rene; Martin, Streibel; Stienstra, Gerard; Kühn, Michael

    2015-04-01

    The IPCC Report 2014 strengthens the need for CO2 storage as part of CCS or BECCS to reach ambitious climate goals despite growing energy demand in the future. The further expansion of renewable energy sources is a second major pillar. As it is today in Germany the weather becomes the controlling factor for electricity production by fossil fuelled power plants which lead to significant fluctuations of CO2-emissions which can be traced in injection rates if the CO2 were captured and stored. To analyse the impact of such changing injection rates on a CO2 storage reservoir. two reservoir simulation models are applied: a. An (smaller) reservoir model approved by gas storage activities for decades, to investigate the dynamic effects in the early stage of storage filling (initial aquifer displacement). b. An anticline structure big enough to accommodate a total amount of ≥ 100 Mega tons CO2 to investigate the dynamic effects for the entire operational life time of the storage under particular consideration of very high filling levels (highest aquifer compression). Therefore a reservoir model was generated. The defined yearly injection rate schedule is based on a study performed on behalf of IZ Klima (DNV GL, 2014). According to this study the exclusive consideration of a pool of coal-fired power plants causes the most intensive dynamically changing CO2 emissions and hence accounts for variations of a system which includes industry driven CO2 production. Besides short-term changes (daily & weekly cycles) seasonal influences are also taken into account. Simulation runs cover a variation of injection points (well locations at the top vs. locations at the flank of the structure) and some other largely unknown reservoir parameters as aquifer size and aquifer mobility. Simulation of a 20 year storage operation is followed by a post-operational shut-in phase which covers approximately 500 years to assess possible effects of changing injection rates on the long-term reservoir

  13. VizieR Online Data Catalog: Dynamical parameters of open clusters (Danilov+, 2012)

    NASA Astrophysics Data System (ADS)

    Danilov, V. M.; Putkov, S. I.

    2012-11-01

    α0 - is the mean value of a virial factor, δ{alp the amplitude of virial factor oscillations, ν={rho}c/{rho}0-is the density contrast ({rho}c - is the mean density of a cluster core, {rho}0 - is the cluster centre density), NK/N - is the ratio of the stars number in a cluster received by King's distribution and by stellar counts, P1-is the period of cluster core oscillations, P2 - is the period of cluster oscillations, δR1/R10-is the relative amplitude of core radius oscillations, λ=σ/σiz, σiz2 - is the velocity dispersion of an isolated virialized cluster, σ2, σ12, σ22 - are the velocity dispersions of nonisolated nonsteady clusters with spherical halo; with ellipsoidal halo elongated to the centre of Galaxy; with ellipsoidal halo elongated to the direction of cluster motion correspondingly. Errors of values α0, δα, δR1/R10, P1 have been estimated by the assumption of the normal distribution of the values M (the mass of a cluster), R2 (the radius of a cluster), {xi} (the ratio of core radius to halo radius), μ (the ratio of core mass to halo mass). Assuming a deviation of one of the four values equal to zero we receive four sections of 1σ-errors ellipsoid. These sections are the spheres of radius 20.5. Taking points on each sphere with the step 0.25*π on angular coordinates we receive 96 points on a surface of the 1σ-errors ellipsoid. The values α0, δα, δR1/R10, P1 were calculated in the 96 points. The centre of the ellipsoidal was used for calculation of the mean values. The errors of the values were computed as root-mean-squire deviations of 96 values from the same mean values. The errors of the others values of the catalog were computed by the errors calculation rule of indirect measuring. (3 data files).

  14. Department of Defense Contractor Establishment Code (CEC). Alphabet Listing. Volume 1

    DTIC Science & Technology

    1992-11-01

    Z1. A >W Z O -z OC U Uex0 -M: 8-..0 -a .w3L.PZU IL K4z0. ~ - ~ t IN -a 0U ZUý.U A ýM . 0UW p0.0pc~-~U am1010 Pco 0.~CI2201.4 1 -4 UZ0. w4 l4 1 P o... ERS1 0U 00 O . 0 N C.00 CI0 1O ClC , C 0t5~b. 0~ 0 L" F5 ~-C~1 0 t- ~ 0 ?o: wOO C O 0 O 0 O C~ C8Nt- j- ccC0 10 * CO00 W 0g- ONO inooWON2m r- -- 0 0 N ý...z .~ j~..Z ~ C~.kJ 091.09 5 0 ao~ o W-Z 1 . PCO 0 3J 2 Z .W C" -4 -u 9z z z m -o0 rQ E ~ ~ ~ i iz QzH .9 HUO0 ~ >0 Q 3 02 4 * mQ0 00 M0 rn0 0U

  15. Generation of superDreicer electric fields in the solar chromosphere

    NASA Astrophysics Data System (ADS)

    Zaitsev, V. V.; Kronshtadtov, P. V.; Stepanov, A. V.

    2016-12-01

    The electric field generation at the front of the current pulse, which originates in a coronal magnetic loop owing to the development of the Rayleigh-Taylor magnetic instability at loop footpoints, has been considered. During the τA ≈ l/V A ≈ 5-25 s time (where l is the plasma plume height entering a magnetic loop as a result of the Rayleigh-Taylor instability), a disturbance related to the magnetic field tension B ϕ( r,t), "escapes" the instability region with the Alfvén velocity in this case. As a result, an electric current pulse Iz( z - V A t), at the front of which an induction magnetic field E z, which is directed along the magnetic tube axis and can therefore accelerate particles, starts propagating along a magnetic loop with a characteristic scale of Δξ ≈ l. In the case of sufficiently large currents, when B ϕ 2/8π > p, an electric current pulse propagates nonlinearly, and a relatively large longitudinal electric field originates E z ≈ 2 I z 3 V A/ c 4a2Bz 2l, which can be larger than the Dreicer field, depending on the electric current value.

  16. Ovine catarrhal fever (Bluetongue): analysis of Culicoides species in seropositive farms.

    PubMed

    Guercio, A; Di Marco, P; Manno, C; Di Bella, C; Purpari, G; Torina, A

    2010-04-01

    Bluetongue (BT) is an orbiviral disease of wild and domestic ruminants, mainly sheep. In Sicily, the first Bluetongue outbreak occurred in October 2000; there have been 76 recorded outbreaks so far. The National Surveillance Plan, based on European Union Commission Decision 138/2001/CE, establishes serological and entomological surveys. This plan consists of controls of seronegative cattle, called 'sentry' as indicators for the presence and circulation of virus in defined areas. To check the seroconversions, the regional territory has been subdivided in 400 km(2) areas including 58 seronegative cattle, periodically checked by serological tests. All positive sera have been tested to detect the specific serotype by the National Reference Centre for Exotic Diseases (CESME) at the Istituto Zooprofilattico Sperimentale Abruzzo e Molise in Teramo (IZS Teramo). Moreover, entomological surveillance has been implemented in seropositive herds, to investigate the presence of insect vectors belonging to Culicoides genus. The goal of the present communication is to report on the different species of Culicoides found in the farms with Bluetongue virus and to investigate on the probable role of new competent vectors. This paper concerns data analysis of 581 light-trap catches collected in 321 farms from 2003 to 2008. We observed that 82% of checked farms were positive for Culicoides spp., and only 10% of the farms were positive for Culicoides imicola.

  17. [Clinical problems in medical mycology: Problem number 49].

    PubMed

    Negroni, Ricardo; Depardo, Roxana; Messina, Fernando; García, Julián; Santiso, Gabriela; Mingrone, Verónica; Marin, Emmanuel; Arechavala, Alicia

    2016-01-01

    The case of a 59-year-old female born in Buenos Aires (Argentina) is presented. She had been diagnosed with HIV in 2007 and received highly active antiretroviral therapy until 2011; she also suffered from diabetes type 2. She had received empirical treatment (pyrimethamine-clindamycin) for cerebral toxoplasmosis. Fifteen days later she suffered a drug-induced skin disorder and was treated in the Dermatology Service of the Hospital Muñiz with corticosteroids. After five weeks she was readmitted to the Infectious Disease Unit due to asthenia, weight loss, left hip pain and weakness in all four limbs. Septic arthritis and aseptic hip necrosis were ruled out. Blood cultures were positive for Staphylococcus aureus and Escherichia coli. The patient received intravenous antibiotics, but before being discharged Acinetobacter baumannii was isolated from blood, catheter and urine cultures, and a new series of antibiotics were prescribed. On the 3rd day she presented encephalic facies, changes of behaviour and disorientation, without nuchal rigidity, Kernig and Brudzinski signs or focal signs. An X-ray computed tomography did not show parenchymal lesions. A yeast identified as Candida albicans was isolated in a cerebrospinal fluid culture. The same yeast was recovered in a new cerebrospinal fluid sample. The isolate was susceptible to amphotericin B and susceptible dose dependent to fluconazole. The patient was treated with amphotericin B (0.7mg/kg plus 800mg fluconazole daily). Three weeks later, new cerebrospinal fluid cultures were negative. Unfortunately, the patient died soon afterwards.

  18. [Clinical problems in medical mycology: Problem number 48].

    PubMed

    Messina, Fernando; Negroni, Ricardo; Santiso, Gabriela; Soto, Isabel; Depardo, Roxana; Villafañe, Maria Florencia; Marin, Emmanuel; Arechavala, Alicia

    2015-01-01

    We present the case of a 42-year-old man, HIV-positive, with low CD4(+) T cell count (31 cells/μl), who was admitted to Hospital de Infecciosas F. J. Muñiz in Buenos Aires (Argentina) due to a severe lower back pain. He had a history of several highly active antiretroviral therapy treatments and he also had diabetes and chronic B and C viral hepatitis. A spinal cord CT scan showed two lytic bone lesions in L2 and L3. A bone biopsy was carried out and its microbiological study allowed the isolation of a methicillin-resistant Staphylococcus aureus. Intravenous vancomycin was prescribed, together with a corset and physical rest. A few days later the patient presented with acute dermatitis with papules, vesicles, scales and erythema, which spread over the whole lumbar region. The mycological study of the scales led to the isolation in culture of Candida albicans and Candida parapsilosis. With the diagnosis of decubitus candidiasis he was initially treated with a topical ointment containing 3% salicylic acid and 6% benzoic acid, but only slow, partial improvement was observed. The treatment was changed to oral fluconazole at a daily dose of 200mg. With the latter the patient showed a rapid, complete clinical response.

  19. Historical aspects of Mexican psychiatry.

    PubMed

    Bayardo, Sergio Javier Villaseñor

    2016-04-01

    Mexican psychiatry initiated since pre-Hispanic times. Historically, treatments were a mixture of magic, science and religion. Ancient Nahuas had their own medical concepts with a holistic view of medicine, considering men and cosmos as a whole. The first psychiatric hospital appeared in 1566 and a more modern psychiatric asylum emerged until 1910. International exchanges of theoretical approaches started in the National University with the visit of Pierre Janet. There were other important figures that influenced Mexican psychiatry, such as Erich Fromm, Henri Ey, Jean Garrabé and Yves Thoret. Regarding Mexican psychiatrists, some of the most important contributors to Mexican psychiatry were José Luis Patiño Rojas, Manuel Guevara Oropeza and Ramón de la Fuente Muñiz. This article includes excerpts from "Clinical Psychiatry", a book by Patiño Rojas where he tries to understand and describe the inner world experienced by patients with schizophrenia; also, the thesis conducted by Guevara Oropeza ("Psychoanalisis"), which is a critical comparison between the theories of Janet and Freud. Finally, we include "The study of consciousness: current status" by Ramón de la Fuente, which leads us through the initial investigations concerning consciousness, its evolution, and the contributions made by psychology, philosophy and neurobiology.

  20. Rosmarinus officinalis essential oil: antiproliferative, antioxidant and antibacterial activities

    PubMed Central

    Hussain, Abdullah Ijaz; Anwar, Farooq; Chatha, Shahzad Ali Shahid; Jabbar, Abdul; Mahboob, Shahid; Nigam, Poonam Singh

    2010-01-01

    The aim of this work was to investigate and compare the antiproliferative, antioxidant and antibacterial activities of Rosmarinus officinalis essential oil, native to Pakistan. The essential oil content from the leaves of R. officinalis was 0.93 g 100g-1. The GC and GC-MS analysis revealed that the major components determined in R. officinalis essential oil were 1,8-cineol (38.5%), camphor (17.1%), α-pinene (12.3%), limonene (6.23%), camphene (6.00%) and linalool (5.70%). The antiproliferative activity was tested against two cancer (MCF-7 and LNCaP) and one fibroblast cell line (NIH-3T3) using the MTT assay, while, the antioxidant activity was evaluated by the reduction of 2, 2-diphenyl-1-picryl hydrazyl (DPPH) and measuring percent inhibition of peroxidation in linoleic acid system. The disc diffusion and modified resazurin microtitre-plate assays were used to evaluate the inhibition zones (IZ) and minimum inhibitory concentration (MIC) of R. officinalis essential oil, respectively. It is concluded from the results that Rosmarinus officinalis essential oil exhibited antiproliferative, antioxidant and antibacterial activities. PMID:24031588

  1. Developmental stage-dependent influence of environmental factors on growth of rural Sundanese children in West Java, Indonesia.

    PubMed

    Sekiyama, Makiko; Roosita, Katrin; Ohtsuka, Ryutaro

    2015-05-01

    This study investigated the growth trajectories and the relative relevance levels of nutrition, disease, and hormonal status at various developmental stages among children in adverse environments to provide population-based empirical evidence for the life history theory. Three years of longitudinal anthropometric data in 1-year intervals were obtained from 418 boys and girls aged 0 to 12 years at recruitment. Following the final measurement, the main survey, which included blood and feces sampling, 3-h interval food consumption recall surveys for energy and nutrient intakes and anthropometry, was performed. Blood and feces were used for detecting, respectively, anemia and hormonal (IGF-I and IGFBP-3) levels as well as intestinal helminthiasis (Ascaris, Trichuris, and hookworm). The major findings of this study are summarized as follows: 1) the growth velocity of the subject children lagged behind international standards during childhood and juvenility but caught up during early adolescence; 2) diseases, both intestinal helminths and anemia, had significant effects on growth in childhood but not at older ages; and 3) hormonal status significantly affected growth in the children, with its highest significance in early adolescence. A larger growth than international standards in early adolescence likely follows programmed hormonal mechanisms after the onset of puberty. The onset of puberty might be associated with adequate amounts of nutrient intake and be mediated by hormonal function, because the IGF-IZ score was significantly correlated with energy and protein intakes at the transitional period from juvenility to adolescence, when puberty occurs.

  2. Tuning the Pseudospin Polarization of Graphene by a Pseudomagnetic Field.

    PubMed

    Georgi, Alexander; Nemes-Incze, Peter; Carrillo-Bastos, Ramon; Faria, Daiara; Viola Kusminskiy, Silvia; Zhai, Dawei; Schneider, Martin; Subramaniam, Dinesh; Mashoff, Torge; Freitag, Nils M; Liebmann, Marcus; Pratzer, Marco; Wirtz, Ludger; Woods, Colin R; Gorbachev, Roman V; Cao, Yang; Novoselov, Kostya S; Sandler, Nancy; Morgenstern, Markus

    2017-03-02

    One of the intriguing characteristics of honeycomb lattices is the appearance of a pseudomagnetic field as a result of mechanical deformation. In the case of graphene, the Landau quantization resulting from this pseudomagnetic field has been measured using scanning tunneling microscopy. Here we show that a signature of the pseudomagnetic field is a local sublattice symmetry breaking observable as a redistribution of the local density of states. This can be interpreted as a polarization of graphene's pseudospin due to a strain induced pseudomagnetic field, in analogy to the alignment of a real spin in a magnetic field. We reveal this sublattice symmetry breaking by tunably straining graphene using the tip of a scanning tunneling microscope. The tip locally lifts the graphene membrane from a SiO2 support, as visible by an increased slope of the I(z) curves. The amount of lifting is consistent with molecular dynamics calculations, which reveal a deformed graphene area under the tip in the shape of a Gaussian. The pseudomagnetic field induced by the deformation becomes visible as a sublattice symmetry breaking which scales with the lifting height of the strained deformation and therefore with the pseudomagnetic field strength. Its magnitude is quantitatively reproduced by analytic and tight-binding models, revealing fields of 1000 T. These results might be the starting point for an effective THz valley filter, as a basic element of valleytronics.

  3. Full-resolution autostereoscopic display using an all-electronic tracking/steering system

    NASA Astrophysics Data System (ADS)

    Gaudreau, Jean-Etienne

    2012-03-01

    PolarScreens is developing a new 3D display technology capable of displaying full HD resolution in each eye without the need for glasses. The technology combines a regular backlight, a 120Hz 3D LCD panel, a vertical Patterned active shutter panel and a head tracking system. The technology relies on a 12-sub-pixel wide alternated pattern encoded in the stereo image to follow the head movement. Alternatively for a passive 3D display, the barrier is made of vertical strip Polarizer Film. This can be applied to any full resolution polarized display like iZ3D, Perceiva, or active retarder 3D display. The end result is a full resolution autostereoscopic display with complete head movement freedom. There are no mechanical moving part (like lenticular) or extra active components to steer the correct L/R image to the user's eyes. The new display has the capacity of displaying 2D/3D information on a pixel per pixel base so there is no need for full screen or windowed 2D/3D switchable apparatus.

  4. A compilation of stellar kinematic groups: stellar streams, moving groups, and associations.

    NASA Astrophysics Data System (ADS)

    Montes, D.

    2010-11-01

    In this contribution we present a compilation of the different stellar kinematic groups analysed in the literature. We include the young and old classical moving groups and superclusters, the recently identified young nearby loose associations as well as other stellar streams identified in recent surveys that contains large number of dwarf and giant stars. I addition, we summarize the high resolution spectroscopic surveys that our group have carried out during the last years aimed to identify cool stars member of these groups. Among these are the surveys of late-type stars possible members to young moving groups (Montes et al. 2001, López-Santiago, et al. 2005, 2006), FGK stars in the solar neighborhood (Martínez-Arnáiz et al. 2008), and RasTyc sample (cross-correlation of the ROSAT All-Sky Survey (RASS) with the TYCHO catalog, Guillout et al. 2008). In order to add new constraints to the membership of these stars to the different stellar kinematic groups we applied an age-oriented method using relative age indicators (Li abundances, chromospheric and coroanal emission and the kinematics) as well as color-magnitude diagrams and pre-main sequence isochrones.

  5. Design and Implementation of a Speech Coding Algorithm at 9600 B/S. Volume 1.

    DTIC Science & Technology

    1980-04-30

    system function becomes H(jw) + ae - jwT + be-j2wT + C e- j 3wT K and the magnitude of the system function is IH(ej t )I2 = + a2 + b2 + c2 + [2a + 2b (a...34%""a o * iAn.hZf a 152 fa Z z ae 4- IAK I K I - Ia.A 0 za II KL - . 4 U 4%U 49 -C6’ a.N m a. z r. 4L "I I h e.. 4a - 3ca 0 oj - G" ta.I. ha I. IqYt W Z...162 -- - - - - 00 z - U zZ z -N u-. se I Il-~ wo 0 f ~ Uz ww! I-I- ( ADib . 00 a, c ta~w ..Uww in at 0 N 0 aD 0 01 ian .j & MD Iz on Ow 4h 4 4e a 1b 3

  6. Dynamic Stall Penetration Experiments on a Swept Wing

    DTIC Science & Technology

    1986-09-12

    Ll *ds �L ’L 91/ L/801 98/9 L/B A~a LenuuV ’A >JD1~d 󈧐q101 !’o UL[)IU2IJ ’PlJ2J 1 (S)’d0i-ufl 1WN0Sb3d ZL jjoda@j LenuuV puooaS -6UiL1 jdamS P UO...S4uDW.jadx3 uoL4P40ud LL4S WURGj ON NOISS3:))WI ON ION ION 1N3LA313IsOi io jboA >ISM £)3,’ Obd AbOdd aor S83SAflN DNi0)%2,j O 3)Dflos o (4Pa dIZ Pup...I4 V)C C*4 mC j LCL I a-L a- a- a-. CL a - -G 0 CC 0- * --l 0 DI D-PS)J 4~~~a a- a- C4 . .A~ L- 6-c~ 6 c) 4-10 0 (N :Lc 0 be d( LL . t C)--A LLN F

  7. Johnston Island Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

    DTIC Science & Technology

    1985-01-01

    09. ~9 g9 9_ ’.- - o-o41 _ cc, ; r. - n n i-r) oil 0ic 2 ci I - m: .j _ .7 . 9P .7 . .91 99. S , ?9.9’I2L. ,JCic. T110. I0.0.00 .3 F.-1 .21<.1Ŝ.3 9c 9...6.9 91 Q 3.71 9A.7 98.17 9P .71 99.7 98.7 98.7 9F.7 95.7 9d. 7 c8.7 99.7 98.7 9. IZ99 ’Si_29 _i.2 1 99. s , 9Q. 99C) a7g: 9 Q -- 29 , .- 2 1 , 9.2 99.3...8217t 2 4 i 13. &-9 a. P4- 9q k < - 8 A:s a- S ig 9 9A 9 gm - ,f 9 c’ .2 9P . og.J 9o.5 99.5 9o. , 99.5, 995,, q 9.5 99.5 9.,3 99. 9 .5 ,6 49,.o 1,.3

  8. Distribution of infective gastrointestinal helminth larvae in tropical erect grass under different feeding systems for lambs.

    PubMed

    Tontini, Jalise Fabíola; Poli, Cesar Henrique Espírito Candal; Bremm, Carolina; de Castro, Juliane Machado; Fajardo, Neuza Maria; Sarout, Bruna Nunes Marsiglio; Castilhos, Zélia Maria de Souza

    2015-08-01

    This study examined tropical pasture contamination dynamics under different feeding systems for finishing lambs. The experiment aimed to evaluate the vertical distribution of gastrointestinal helminth infective larvae (L3) in erect grass subjected to grazing and to assess the parasite load and its impact on lamb performance in three production systems. Three treatments based on Aruana grass (Panicum maximum cv. IZ-5) were as follows: T1, grass only; T2, grass with 1.5% of body weight (BW) nutrient concentrate supplementation; and T3, grass with 2.5% BW concentrate supplementation. The randomized block design had three replicates of three treatments, with six lambs per replicate. L3 were recovered from three pasture strata (upper, middle, and bottom), each representing one third of the sward height, and correlated with microclimatic data. Significant differences (P < 0.05) were observed among treatments in the L3 recovery. Despite different grass heights between treatments and microclimates within the sward, the L3 concentration generally did not differ significantly among the three strata within a treatment (P > 0.05). Pasture microclimate did not correlate with larval recovery. At the end of the experiment, the animal fecal egg count was similar among treatments (P > 0.05). The results indicated that different lamb feeding systems in a tropical erect grassland caused differences in grass height but did not affect the distribution of infective larvae among strata. Larvae were found from the base to the top of the grass sward.

  9. Air Force Office of Scientific Research. AFOSR Technical Report Summaries

    DTIC Science & Technology

    1993-06-01

    4i ImI z CA 0 LO 0 CA 1- 1. Ii .I & -t U 5.G 0- 0 5’ 0 1.-G - 0 *1-G xh a -1- 0 0 CL1-I= >- . 4 1-. .0 ), 0. 0 00 4 w~~~~ ~ Ow 0 0hZI yi AI I- -j40 U...CA 00 2W "UL Lee a’ 2-C- 0-(~U ot L ft-.. 2 40 . s~~ L 26.- 2 ""U 4 4l 4c 0j 0.0 .1 4 3 04 (A 4 0.4 !!1 L Vn (44z 4 )- 0~~ 0.0 4 ZA 4 (40~ Z0 0 a L 0...1 0 L) C4-Lm -ia .o.- 0 m xL h4 a mac SEUL - O C -C n-.n 00 -W0M IZ X 4 a- in to 10 0 mac. S .L < c u 0 L UO L - - C a ř- -Kix Z a 0 5-L@ CLC UUO>Ez 0

  10. Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex.

    PubMed

    Liu, Xiuxin; Sun, Lin; Torii, Masaaki; Rakic, Pasko

    2012-05-22

    The prospective pyramidal neurons, migrating from the proliferative ventricular zone to the overlaying cortical plate, assume multipolar morphology while passing through the transient subventricular zone. Here, we show that this morphogenetic transformation, from the bipolar to the mutipolar and then back to bipolar again, is associated with expression of connexin 43 (Cx43) and, that knockdown of Cx43 retards, whereas its overexpression enhances, this morphogenetic process. In addition, we have observed that knockdown of Cx43 reduces expression of p27, whereas overexpression of p27 rescues the effect of Cx43 knockdown in the multipolar neurons. Furthermore, functional gap junction/hemichannel domain, and the C-terminal domain of Cx43, independently enhance the expression of p27 and promote the morphological transformation and migration of the multipolar neurons in the SVZ/IZ. Collectively, these results indicate that Cx43 regulates the passage of migrating neurons through their multipolar stage via p27 signaling and that interference with this process, by either genetic and/or environmental factors, may cause cortical malformations.

  11. Detailed surface photometry of the cD galaxies NGC 4839 and NGC 4874

    NASA Astrophysics Data System (ADS)

    Ali, Gamal B.; Shaban, Eman A.; Amin, Magdy Y.; Rassem, M. A.

    2014-08-01

    We present a detailed photometric study of the cD galaxies NGC 4839 and NGC 4874 based on the technique of surface photometry by fitting ellipses to the isophotes of the galaxies in the u, g, r, i, and z bands using Data Release 7 (DR7) of the Sloan Digital Sky Survey (SDSS). The motivation of this paper is to study the properties (e.g. break radius and surface brightness, color gradient, etc.) of the extended envelope of the two cD galaxies. The surface brightness profile in each band is obtained and fitted to the de Vaucouleurs r 1/4 model. A deviation of the observed profile brighter than the fitted r 1/4 model is noticed especially in the outer part of each galaxy. The profiles of ellipticity, position angle, B4 and shifts with respect to the center of each isophote are also obtained. The color index profiles, u-g, g-r, r-i, and i-z are also obtained and no significant color gradients are noticed except in the outer parts of the two galaxies. The integrated magnitude in each band and color indices are obtained and found to be in good agreement with the published ones.

  12. Intergalactic Lyman continuum photon budget in the past 5 billion years

    NASA Astrophysics Data System (ADS)

    Gaikwad, Prakash; Khaire, Vikram; Choudhury, Tirthankar Roy; Srianand, Raghunathan

    2017-04-01

    We constrain the H I photoionization rate (Γ _{H I}) at z ≲ 0.45 by comparing the flux probability distribution function and power spectrum of the Lyα forest data along 82 Quasi-Stellar Object (QSO) sightlines obtained using Cosmic Origins Spectrograph with models generated from smoothed particle hydrodynamic simulations. We have developed a module named 'Code for Ionization and Temperature Evolution (CITE)' for calculating the intergalactic medium (IGM) temperature evolution from high to low redshifts by post-processing the GADGET-2 simulation outputs. Our method, that produces results consistent with other simulations, is computationally less expensive thus allowing us to explore a large parameter space. It also allows rigorous estimation of the error covariance matrix for various statistical quantities of interest. We find that the best-fitting Γ _{H I}(z) increases with z and follows (4 ± 0.1) × 10-14 (1 + z)4.99 ± 0.12 s-1. At any given z, the typical uncertainties Δ Γ _{H I} / Γ _{H I} are ∼25 per cent that contains not only the statistical errors but also those arising from possible degeneracy with the thermal history of the IGM and cosmological parameters and uncertainties in fitting the QSO continuum. These values of Γ _{H I} favour the scenario where only QSOs contribute to the ionizing background at z < 2. Our derived 3σ upper limit on average escape fraction is 0.008, consistent with measurements of low-z galaxies.

  13. Evaluating the impact of climate change on groundwater resources in a small Mediterranean watershed.

    PubMed

    Ertürk, Ali; Ekdal, Alpaslan; Gürel, Melike; Karakaya, Nusret; Guzel, Cigdem; Gönenç, Ethem

    2014-11-15

    Western Mediterranean Region of Turkey is subject to considerable impacts of climate change that may adversely affect the water resources. Decrease in annual precipitation and winter precipitation as well as increase in temperatures are observed since 1960s. In this study, the impact of climate change on groundwater resources in part of Köyceğiz-Dalyan Watershed was evaluated. Evaluation was done by quantifying the impacts of climate change on the water budget components. Hydrological modeling was conducted with SWAT model which was calibrated and validated successfully. Climate change and land use scenarios were used to calculate the present and future climate change impacts on water budgets. According to the simulation results, almost all water budget components have decreased. SWAT was able to allocate less irrigation water because of the decrease of overall water due to the climate change. This resulted in an increase of water stressed days and temperature stressed days whereas crop yields have decreased according to the simulation results. The results indicated that lack of water is expected to be a problem in the future. In this manner, investigations on switching to more efficient irrigation methods and to crops with less water consumption are recommended as adaptation measures to climate change impacts.

  14. Word Frequency Analysis. MOS: 43E. Skill Levels 1 & 2

    DTIC Science & Technology

    1981-05-01

    IEq3r !r- t CLOArC- 2 ~.K1 CLC72 I-NG3 CK’C-ftc 7~5 CLV ’.4A 1 --Llj4’iNC- 2L I .1J~~1J9C.-KE IZ Cli:W1 3 Cflr*R! al~: __ _ _ __ _ _ _ - -_ _ 13 tu.v... 13 crr21"LYc U. 1L~~S !4 UTtVMT*ZX 13 t=4.45 I cw rT I TJ l C~LJ. EI0A S 25~ ;Wi VAV 1l cw". ZV 3 LTLiN=1 I CTA Z 13JPE;l to ’~U i i ;31 nvTx-lqt 3 ~U...IszfctLJ t 0 ~ uA 4 A e FL:tTnt 1𔃽:-c1 F a LTV 5 Ftmr7H 2F-;.Yt- 7 CSl 74 F. LTS 13 LEE Z!fl9rl1tF ____________ 4_ _____________ 1*t= t

  15. DECam Survey for Substellar and Low-mass Stellar Members of Sco-Cen

    NASA Astrophysics Data System (ADS)

    Mamajek, Eric E.; Moolekamp, Fred; James, David; Luhman, Kevin; Pecaut, Mark; Metchev, Stanimir A.; Denbo, Sara; Bell, Cameron P. M.

    2017-01-01

    We present the results of a DECam imaging survey for low-mass stellar and substellar objects in the nearby Sco-Cen OB association. The DECam survey was taken in izY bands in 2013 and 2015 and covered $\\sim$87 deg$^2$ in the two nearest and oldest subgroups, Upper Cen-Lup ($\\sim$142 pc) and Lower Cen-Cru ($\\sim$118 pc; both with mean ages $\\sim$16 Myr). Using color-magnitude and proper motion selection, we identify 391 candidate Sco-Cen members with masses ranging from near the D-burning limit of $\\sim$13 M$_{Jup}$, through the H-burning limit, up to $\\sim$0.4 M$_\\odot$. Our initial spectroscopic follow-up with the ARCoIRIS and COSMOS spectrographs for 19 objects have yielded young M dwarfs showing signatures of low surface-gravity. Our survey yields the first constraints on the substellar and low-mass initial mass function and disk fraction in the two oldest Sco-Cen subgroups, and will yield a large sample of young, low-surface gravity M and L-type objects of constrained age, distance, and chemical composition. We acknowledge support from NSF award AST-1313029 and the REU Site in Physics and Astrophysics at the University of Rochester supported by NSF award PHY-1156339.

  16. Outpatient Nonavailability Statement Procedures, Health Services Command Catchment Areas, Second Quarter FY 1993 with Comparisons to First Quarter FY 1993

    DTIC Science & Technology

    1993-04-16

    9n W! 0. - 1ý z1 - 9w -u : C9 L& x u 0,0 m L3* omp m rayo co 00 0 r4U iao a, - -C9~ m iz .J J ,4cfC4z Ge .4 th in Nn ini~ N 0 . - 0M 4Im o-1~ 4a4 a...n o . 3:W N `0It C 0.O In ?K. 0 )10 S C j0 .0 > .0N ~ O -r . -~r- 0 I0-i cc0 CL.Q 0 ~ N’- t X . 0. 0.0 kn .t.O 0 N- ýA 0. O L.MwNc 0 ’ C. C’ . c, ’r...0C. 0> In .- -fn 0 00. 0. -) 0 O 0 I- nI 1 l L I.-~~ ~ Nui -j V). Un 4A𔄀 f m n U =0 -K 0 4 A.f u x ý U) 00 i n f- ’ , ý O ac -00 L) b- -C u) ý .- 𔃻

  17. Relationship between Food Intake and Sleep Pattern in Healthy Individuals

    PubMed Central

    Crispim, Cibele Aparecida; Zimberg, Ioná Zalcman; dos Reis, Bruno Gomes; Diniz, Rafael Marques; Tufik, Sérgio; de Mello, Marco Túlio

    2011-01-01

    Study Objectives: The purpose of this study was to analyze the relationship between food intake and sleep patterns in healthy individuals. Methods: Fifty-two healthy volunteers (27 women and 25 men) were recruited to participate in the study. Volunteers underwent sleep evaluation through nocturnal polysomnography and completed a 3-day food diary to evaluate food intake. Results: No differences in sleep patterns were observed in either gender, except in the percentage of stage 1 sleep, which was greater in men. Different correlations were observed between sleep and dietary variables according to gender. The correlation between dietary and sleep variables in men indicated a negative relationship between nocturnal fat intake and the sleep latency, including REM sleep. The percentage of nocturnal fat intake correlated with sleep efficiency, sleep latency, REM latency, stage 2 sleep, REM sleep, and wake after sleep onset (WASO) in women. The percentage of nocturnal caloric intake correlated with sleep latency and efficiency in women. Conclusions: We conclude that food intake during the nocturnal period is correlated with negative effects on the sleep quality of healthy individuals. Indeed, food intake near the sleeping period (dinner and late night snack) was negatively associated with sleep quality variables. More studies are necessary to elucidate the real effect of food intake on sleep. Citation: Crispim CA; Zimberg IZ; dos Reis BG; Diniz RM; Tufik S; de Mello MT. Relationship between food intake and sleep pattern in healthy individuals. J Clin Sleep Med 2011;7(6):659-664. PMID:22171206

  18. Further perspective on the theory of heteronuclear decoupling.

    PubMed

    Skinner, Thomas E

    2014-11-01

    An exact general theory of heteronuclear decoupling is presented for spin-1/2 IS systems. RF irradiation applied to the I spins both modifies and generates additional couplings between states of the system. The recently derived equivalence between the dynamics of any N-level quantum system and a system of classical coupled harmonic oscillators makes explicit the exact physical couplings between states. Decoupling is thus more properly viewed as a complex intercoupling. The sign of antiphase magnetization plays a fundamental role in decoupling. A one-to-one correspondence is demonstrated between ±2SyIz and the sense of the S-spin coupling evolution. Magnetization Sx is refocused to obtain the desired decoupled state when ∫2SyIzdt=0. The exact instantaneous coupling at any time during the decoupling sequence is readily obtained in terms of the system states, showing that the creation of two-spin coherence is crucial for reducing the effective scalar coupling, as required for refocusing to occur. Representative examples from new aperiodic sequences as well as standard cyclic, periodic composite-pulse and adiabatic decoupling sequences illustrate the decoupling mechanism. The more general aperiodic sequences, obtained using optimal control, realize the potential inherent in the theory for significantly improved decoupling.

  19. Morphology and the Color-mass Diagram as Clues to Galaxy Evolution at z&approx1

    NASA Astrophysics Data System (ADS)

    Powell, Meredith C.; Urry, C. Megan; Cardamone, Carolin N.; Simmons, Brooke D.; Schawinski, Kevin; Young, Sydney; Kawakatsu, Mari

    2017-01-01

    We study the significance of mergers in the quenching of star formation in galaxies at z∼ 1 by examining their color–mass distributions for different morphology types. We perform two-dimensional light profile fits to GOODS iz images of ∼5000 galaxies and X-ray selected active galactic nucleus (AGN) hosts in the CANDELS/GOODS-north and south fields in the redshift range 0.7< z< 1.3. Distinguishing between bulge-dominated and disk-dominated morphologies, we find that disks and spheroids have distinct color–mass distributions, in agreement with studies at z∼ 0. The smooth distribution across colors for the disk galaxies corresponds to a slow exhaustion of gas, with no fast quenching event. Meanwhile, blue spheroids most likely come from major mergers of star-forming disk galaxies, and the dearth of spheroids at intermediate green colors is suggestive of rapid quenching. The distribution of moderate luminosity X-ray AGN hosts is even across colors, in contrast, and we find similar numbers and distributions among the two morphology types with no apparent dependence on Eddington ratio. The high fraction of bulge-dominated galaxies that host an AGN in the blue cloud and green valley is consistent with the scenario in which the AGN is triggered after a major merger, and the host galaxy then quickly evolves into the green valley. This suggests AGN feedback may play a role in the quenching of star formation in the minority of galaxies that undergo major mergers.

  20. Balsscallichirus Sakai, 2011 (Decapoda: Axiidea: Callianassidae) in the fossil record: systematics and palaeobiogeography

    PubMed Central

    Hyžný, Matúš

    2016-01-01

    The fossil record of the ghost shrimp genus Balsscallichirus Sakai, 2011 (Crustacea: Decapoda: Callianassidae) is revised. Barnardcallichirus Sakai, 2011 and Tirmizicallichirus Sakai, 2011 are considered subjective synonyms of Balsscallichirus. Based on the examination of extant species it is argued that the morphology of the major cheliped merus, in combination with other hard part morphology characters, is sufficient for assignment of the fossil material into the genus. Main identifying characters are on merus which is keeled along its midline and its lower half is tuberculated; its lower margin possesses broad proximal meral hook continuing into a lobe distally; the entire lower margin is subdivided into numerous irregularly spaced spines. Three species, Callianassa sismondai A. Milne-Edwards, 1860, C. floriana Glaessner, 1928, and Podocallichirus laepaensis Hyžný & Muñiz, 2012, originally described from the Miocene of Italy, Austria and Spain, respectively, are assigned to Balsscallichirus herein. Neocallichirus wellsi Schweitzer, Feldmann & Gingerich, 2004 from the Upper Eocene of Pakistan is tentatively assigned to that genus as well. Spatial and temporal distribution of the genus indicates that at least since the Oligocene, and possibly even sooner (the Late Eocene), the genus has been restricted to the Western Tethys Region. Later, it migrated also into West Atlantic establishing present day communities. PMID:27499568

  1. All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 4. Sage Hen, California-Yolo, California.

    DTIC Science & Technology

    1987-01-01

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  2. Prime Contract Awards Over $25,000 by Major System, Contractor and State, FY 88. Part 1. (AAA-AHR).

    DTIC Science & Technology

    1988-01-01

    IXAWIlIn 0W M O 0. < c _XI I 0" > w~-< a -o w m10 In ag I ()13II,0 M jj~< ~ ~ z ~ Il. "R _ W: W WOYWI.a0-<-4WZZ W Wil a z z i U)_00 - - QU ŗ-f4...U." Z )W I--al-a 0 4 L~-4 -0" 011 0 11 H~ Co. aw Z0Zw iE.u0 0Z4Z.nuu~uloonowo 0olnc 000 00000 041r ) -w aI_ ai I ~ U)Z -I 0 I~-m) wO OwinmNa 0 a0 -Iwo...0114Z0W&A W 0 I4 Ia a ag a4- E1- C4E L 1 c ---- 1101- II 3t--4 -4 3t X 3 t m 211 V~ 420 40 4 0 4 4 -II) 41114-4 4 il a41 -4 oo41 -4 I 1- IZ ~ ~ U W

  3. New Quasar Surveys with WIRO: Colors of ~1000 Quasars at 0 < z < 3

    NASA Astrophysics Data System (ADS)

    Witherspoon, Catherine; Bassett, Neil; Deam, Sophie; Dixon, Don; Griffith, Emily; Harvey, William; Lee, Daniel; Lyke, Bradley; Haze Nunez, Evan; Parziale, Ryan; Myers, Adam D.; Findlay, Joseph; Kobulnicky, Henry A.; Dale, Daniel A.

    2017-01-01

    We present the colors of quasars observed as part of an imaging campaign using the Wyoming Infrared Observatory (WIRO). A major goal of the campaign was to calibrate the magnitudes of point sources in the Sloan Digital Sky Survey (SDSS) photometric system using WIRO's new DoublePrime camera. The sample we study is comprised of approximately 1000 quasars with redshift 0 < z < 3 that were matched to spectroscopically confirmed quasars in SDSS Stripe 82. As expected from earlier imaging surveys of quasars, we find that quasars occupy a region of u-g vs. g-r color-color space that is distinct from that of stars. The quasar u-g colors are considerably bluer than those of the stars while quasar g-r colors are only slightly bluer than the g-r colors of the majority of the observed stars. There is a noticeable correlation between the quasar redshift and the corresponding u-g color. As the redshift of a quasar increases, its u-g color becomes redder. In the g-r vs. r-i and r-i vs. i-z color-color spaces, the quasars occupy regions that overlap with the regions occupied by the majority of the stars, again in excellent agreement with the expectation from earlier surveys.This work is supported by the National Science Foundation under REU grant AST 1560461.

  4. X-ray fluorescence analysis of yellow pigments in altarpieces by Valencian artists of the XV and XVI centuries

    NASA Astrophysics Data System (ADS)

    Ferrero, J. L.; Roldán, C.; Ardid, M.; Navarro, E.

    1999-02-01

    XRF analysis has allowed a quick and precise detection and identification of the inorganic elements that compose the yellow pigments in altarpieces of the XV and XVI centuries painted by the Valencian artists Miguel Alcañiz, Vicente Macip, Juan de Juanes, Hernando Yáñez de la Almedina and Hernando Llanos. The analyses have been carried out with an XRF portable system that consists of a tube of X-rays and detectors of Si(Li) and cadmium zinc telluride. This system has enabled a non-aggressive and non-destructive analysis of many pieces at the Museo de Bellas Artes of Valencia (Spain). Among the yellow pigments we have identified a pigment composed by lead and tin oxides named lead-tin yellow (Pb 2SnO 4), frequently used in European paintings from the XIV century until the first half of the XVIII century. This fact demonstrates the influence of elements and pictorial techniques from Europe to the region of Valencia.

  5. A Dark Energy Camera Search for an Optical Counterpart to the First Advanced LIGO Gravitational Wave Event GW150914

    DOE PAGES

    Soares-Santos, M.

    2016-05-27

    We report initial results of a deep search for an optical counterpart to the gravitational wave event GW150914, the first trigger from the Advanced LIGO gravitational wave detectors. We used the Dark Energy Camera (DECam) to image a 102 degmore » $^2$ area, corresponding to 38% of the initial trigger high-probability sky region and to 11% of the revised high-probability region. We observed in i and z bands at 4-5, 7, and 24 days after the trigger. The median $$5\\sigma$$ point-source limiting magnitudes of our search images are i=22.5 and z=21.8 mag. We processed the images through a difference-imaging pipeline using templates from pre-existing Dark Energy Survey data and publicly available DECam data. Due to missing template observations and other losses, our effective search area subtends 40 deg$$^{2}$$, corresponding to 12% total probability in the initial map and 3% of the final map. In this area, we search for objects that decline significantly between days 4-5 and day 7, and are undetectable by day 24, finding none to typical magnitude limits of i= 21.5,21.1,20.1 for object colors (i-z)=1,0,-1, respectively. Our search demonstrates the feasibility of a dedicated search program with DECam and bodes well for future research in this emerging field.« less

  6. Effective Hamiltonians by optimal control: solid-state NMR double-quantum planar and isotropic dipolar recoupling.

    PubMed

    Tosner, Zdenek; Glaser, Steffen J; Khaneja, Navin; Nielsen, Niels Chr

    2006-11-14

    We report the use of optimal control algorithms for tailoring the effective Hamiltonians in nuclear magnetic resonance (NMR) spectroscopy through sophisticated radio-frequency (rf) pulse irradiation. Specifically, we address dipolar recoupling in solid-state NMR of powder samples for which case pulse sequences offering evolution under planar double-quantum and isotropic mixing dipolar coupling Hamiltonians are designed. The pulse sequences are constructed numerically to cope with a range of experimental conditions such as inhomogeneous rf fields, spread of chemical shifts, the intrinsic orientation dependencies of powder samples, and sample spinning. While the vast majority of previous dipolar recoupling sequences are operating through planar double-or zero-quantum effective Hamiltonians, we present here not only improved variants of such experiments but also for the first time homonuclear isotropic mixing sequences which transfers all I(x), I(y), and I(z) polarizations from one spin to the same operators on another spin simultaneously and with equal efficiency. This property may be exploited to increase the signal-to-noise ratio of two-dimensional experiments by a factor of square root 2 compared to conventional solid-state methods otherwise showing the same efficiency. The sequences are tested numerically and experimentally for a powder of (13)C(alpha),(13)C(beta)-L-alanine and demonstrate substantial sensitivity gains over previous dipolar recoupling experiments.

  7. Application of optimal control theory to the design of broadband excitation pulses for high-resolution NMR.

    PubMed

    Skinner, Thomas E; Reiss, Timo O; Luy, Burkhard; Khaneja, Navin; Glaser, Steffen J

    2003-07-01

    Optimal control theory is considered as a methodology for pulse sequence design in NMR. It provides the flexibility for systematically imposing desirable constraints on spin system evolution and therefore has a wealth of applications. We have chosen an elementary example to illustrate the capabilities of the optimal control formalism: broadband, constant phase excitation which tolerates miscalibration of RF power and variations in RF homogeneity relevant for standard high-resolution probes. The chosen design criteria were transformation of I(z)-->I(x) over resonance offsets of +/- 20 kHz and RF variability of +/-5%, with a pulse length of 2 ms. Simulations of the resulting pulse transform I(z)-->0.995I(x) over the target ranges in resonance offset and RF variability. Acceptably uniform excitation is obtained over a much larger range of RF variability (approximately 45%) than the strict design limits. The pulse performs well in simulations that include homonuclear and heteronuclear J-couplings. Experimental spectra obtained from 100% 13C-labeled lysine show only minimal coupling effects, in excellent agreement with the simulations. By increasing pulse power and reducing pulse length, we demonstrate experimental excitation of 1H over +/-32 kHz, with phase variations in the spectra <8 degrees and peak amplitudes >93% of maximum. Further improvements in broadband excitation by optimized pulses (BEBOP) may be possible by applying more sophisticated implementations of the optimal control formalism.

  8. Role of radiosensitivity and radioresistance genetic markers in hematological and cardiovascular disease in persons exposed after the Chornobyl accident.

    PubMed

    Minchenko, J M; Dyagil, I S; Dmytrenko, O O; Dmytrenko, I V; Shlaykhtychenko, T Y; Gavrylenko, T I; Biliy, D O; Khomenko, V I; Bebeshko, V G

    2013-01-01

    Meta roboty poljagala u vyvchenni vnesku imunogenetychnoi' komponenty v formuvannja postradiacijnyh efektiv u viddalenomu periodi pislja oprominennja na rivni imunnogo reaguvannja organizmu ljudyny, jak prognostychnogo kryteriju ocinky ryzyku realizacii' radiacijno-asocijovanoi' somatychnoi' patologii'. Ob’jektom doslidzhennja buly rekonvalescenty gostroi' promenevoi' hvoroby (GPH) I stupenja tjazhkosti i 88 pacijentiv z analogichnym radiacijnym anamnezom, ale z nepidtverdzhenym diagnozom GPH, 73 pacijenty, jaki majut' status uchasnykiv likvidacii' naslidkiv Chornobyl's'koi' katastrofy (ULNChK) z hronichnoju ishemichnoju hvoroboju sercja (HIHS), 65 pacijentiv – ULNChK bez HIHS, 120 neoprominenyh pacijentiv z HIHS. Pacijenty z onkogematologichnoju patologijeju – 256 osib. 500 praktychno zdorovyh osib – populjacijnyj kontrol'. Rezul'taty. Na osnovi vyvchennja spektru imunologichnyh, gematologichnyh ta molekuljarno-genetychnyh porushen' u spivvidnoshenni z imunogenetychnymy chynnykamy vyznacheni markery ryzyku realizacii' genetychnoi' shyl'nosti do onkogematologichnoi' ta sercevo-sudynnoi' patologii' u zaznachenyh kontyngentiv. Vysnovky. Otrymani dani svidchat' pro te, shho odnym iz mehanizmiv formuvannja radiacijno-asocijovanoi' mul'tyfaktorial'noi' patologii', je realizacija HLA-genetychnoi' shyl'nosti do zahvorjuvannja, jak na rivni rozladiv u gemopoezi ta imunopoezi, tak i na rivni zahvorjuvannja v cilomu, a nosijstvo v feno/genotypi markeriv radiochutlyvosti pidvyshhuje ryzyk realizacii' patologichnogo procesu v umovah oprominennja.

  9. Cytoplasmic p21(CIP1/WAF1), ERK1/2 activation, and cytoskeletal remodeling are associated with the senescence-like phenotype after airborne particulate matter (PM(10)) exposure in lung cells.

    PubMed

    Sánchez-Pérez, Yesennia; Chirino, Yolanda I; Osornio-Vargas, Álvaro Román; Herrera, Luis A; Morales-Bárcenas, Rocío; López-Saavedra, Alejandro; González-Ramírez, Imelda; Miranda, Javier; García-Cuellar, Claudia María

    2014-02-10

    The exposure to particulate matter with a mean aerodynamic diameter ≤10 μm (PM10) from urban zones is considered to be a risk factor in the development of cancer. The aim of this work was to determine if PM10 exposure induces factors related to the acquisition of a neoplastic phenotype, such as cytoskeletal remodeling, changes in the subcellular localization of p21(CIP1/WAF1), an increase in β-galactosidase activity and changes in cell cycle. To test our hypothesis, PM10 from an industrial zone (IZ) and a commercial zone (CZ) were collected, and human adenocarcinoma lung cell cultures (A549) were exposed to a sublethal PM10 concentration (10 μg/cm(2)) for 24 h and 48 h. The results showed that PM10 exposure induced an increase in F-actin stress fibers and caused the cytoplasmic stabilization of p21(CIP1/WAF1) via phosphorylation at Thr(145) and Ser(146) and the phosphorylation of ERK1/2 on Thr(202). Changes in the cell cycle or apoptosis were not observed, but an increase in β-galactosidase activity was detected. The PM10 from CZ caused more dramatic effects in lung cells. We conclude that PM10 exposure induced cytoplasmic p21(CIP1/WAF1) retention, ERK1/2 activation, cytoskeleton remodeling and the acquisition of a senescence-like phenotype in lung cells. These alterations could have mechanistic implications regarding the carcinogenic potential of PM10.

  10. Particulate matter (PM₁₀) induces metalloprotease activity and invasion in airway epithelial cells.

    PubMed

    Morales-Bárcenas, Rocío; Chirino, Yolanda I; Sánchez-Pérez, Yesennia; Osornio-Vargas, Álvaro Román; Melendez-Zajgla, Jorge; Rosas, Irma; García-Cuellar, Claudia María

    2015-09-17

    Airborne particulate matter with an aerodynamic diameter ≤ 10 μm (PM10) is a risk factor for the development of lung diseases and cancer. The aim of this work was to identify alterations in airway epithelial (A549) cells induced by PM10 that could explain how subtoxic exposure (10 μg/cm(2)) promotes a more aggressive in vitro phenotype. Our results showed that cells exposed to PM10 from an industrial zone (IZ) and an urban commercial zone (CZ) induced an increase in protease activity and invasiveness; however, the cell mechanism is different, as only PM10 from CZ up-regulated the activity of metalloproteases MMP-2 and MMP-9 and disrupted E-cadherin/β-catenin expression after 48 h of exposure. These in vitro findings are relevant in terms of the mechanism action of PM10 in lung epithelial cells, which could be helpful in understanding the pathogenesis of some human illness associated with highly polluted cities.

  11. Nonmarket valuation of water quality in a rural transition economy in Turkey applying an a posteriori bid design

    NASA Astrophysics Data System (ADS)

    Bederli Tümay, Aylin; Brouwer, Roy

    2007-05-01

    In this paper, we investigate the economic benefits associated with public investments in wastewater treatment in one of the special protected areas along Turkey's touristic Mediterranean coast, the Köyceǧiz-Dalyan watershed. The benefits, measured in terms of boatable, fishable, swimmable and drinkable water quality, are estimated using a public survey format following the contingent valuation (CV) method. The study presented here is the first of its kind in Turkey. The study's main objective is to assess public perception, understanding, and valuation of improved wastewater treatment facilities in the two largest population centers in the watershed, facing the same water pollution problems as a result of lack of appropriate wastewater treatment. We test the validity and reliability of the application of the CV methodology to this specific environmental problem in a rural transition economy and evaluate the transferability of the results within the watershed. In order to facilitate willingness to pay (WTP) value elicitation we apply a novel dichotomous choice procedure where bid design takes place a posteriori instead of a priori. The statistical efficiency of different bid vectors is evaluated in terms of the estimated welfare measures' mean square errors using Monte Carlo simulation. The robustness of bid function specification is analyzed through average WTP and standard deviation estimated using parametric and nonparametric methods.

  12. Interpretation of Flood-Illuminated Adaptive Optics Images in Subjects with Retinitis Pigmentosa.

    PubMed

    Gale, Michael J; Feng, Shu; Titus, Hope E; Smith, Travis B; Pennesi, Mark E

    2016-01-01

    The purpose of this study was to correlate features on flood-illuminated adaptive optics (AO) images with color fundus, fundus autofluorescence (FAF) and spectral domain optical coherence tomography (SD-OCT) images in patients with retinitis pigmentosa (RP). We imaged 39 subjects diagnosed with RP using the rtx1™ flood-illuminated AO camera from Imagine Eyes (Orsay, France). We observed a correlation between hyper-autofluoresence changes on FAF, disruption of the interdigitation zone (IZ) on SD-OCT and loss of reflective cone profiles on AO. Four main patterns of cone-reflectivity were seen on AO: presumed healthy cone mosaics, hypo-reflective blurred cone-like structures, higher frequency disorganized hyper-reflective spots, and lower frequency hypo-reflective spots. These regions were correlated to progressive phases of cone photoreceptor degeneration observed using SD-OCT and FAF. These results help provide interpretation of en face images obtained by flood-illuminated AO in subjects with RP. However, significant ambiguity remains as to what truly constitutes a cone, especially in areas of degeneration. With further refinements in technology, flood illuminated AO imaging has the potential to provide rapid, standardized, longitudinal and lower cost imaging in patients with retinal degeneration.

  13. [Dr Srećko Marac (1921-1985): a physician, sychiatrist/phychotherapist, and a poet].

    PubMed

    Radovancević, Ljubomir; Pavlović, Eduard

    2009-01-01

    Srećko Marac was born in Susak in 1921 and died in Zagreb in 1990. Having completed the Susak grammar school, he moved to Padua and later to Zagreb to study medicine. During WW2 he dropped the studies and joined the antifascist resistance known as the People's Liberation War. After the war, he completed medical studies in Zagreb. He worked as army physician in Bjelovar and in the Military Hospital in Zagreb. He specialised in psychiatry and practiced psychotherapy in the former Zagreb Mental Health Centre. In 1973, he published his first selection of poems wrought over a long time, with a simple title Pjesme (Poems). The aim of this article was to take a better look at this 1973 collection, see its structure and composition, its content, moods, and ways it communicates to the reader. The collection consists of five parts: Ad tyrannos, Iz partizana (from Resistance), Lutanja/ traZenja/snovi...(Roamings, Quests, Dreams...), Satire i kusanja humora (Satire and Attempts at Humour), and More/brda i domovina (Sea, Hills, and Homeland). Instead of a conclusion, this article proposes to save this wonderful and compassionate poetphysician from oblivion.

  14. All Prime Contract Awards by State or Country, Place and Contractor. Part 3. (Lemon Grove, California-San Bruno, California)

    DTIC Science & Technology

    1989-01-01

    114I 4 -4 I* .4- 4-4 N 4 ( 4N on 4 -4 -4 in 4 1I1 HW4N4HIH1 " ’-4-4* HU-4 HO- U- U- HN ION VN 4 IUD 󈧈 gg2H00-INO 110-2 020 02 02 02 0 (D IZ r2 (D 02...Nl < w0) w LLI :1ICO I Mri 11--4 0.-40)= <-I w D 00 n W N 0 ~ 1 _III CN 11>0C -(001--~ ( W 1- 00 Lot1 (nc l) 0C-- 0 a)-411W ICON cc~ 44N2 04 ’I z w4...WI H I 0000 If 0-4 000000- 000000000 -400 ’-4000000 -400)0 CI 0 % -40 .0 .4000 .0 00 110 󈧅 0 M I M 11 - >4. 1 4 2 40 10 cmNe o- . 00: II MrI 0000

  15. KMOS Clusters and VIRIAL GTO Surveys

    NASA Astrophysics Data System (ADS)

    Wilman, D.; Bender, R.; Davies, R. L.; Mendel, J. T.; Chan, J.; Beifiori, A.; Houghton, R.; Saglia, R.; Schreiber, N. Förster; Wuyts, S.; van Dokkum, P.; Cappellari, M.; Stott, J.; Smith, R.; Fossati, M.; Kulkarni, S.; Seitz, S.; Fabricius, M.; Sharples, R.; Brammer, G.; Nelson, E.; Momcheva, I.; Wegner, M.; Lewis, I.

    2015-02-01

    We present the KMOS (K-band Multi-Object Spectrograph) Cluster and VIRIAL (VLT IR IFU Absorption Line) Guaranteed Time Observation (GTO) programs. KMOS provides 24 arms each feeding an integral field unit (14×14 spaxels of 0.2'' pixels) for IZ, YJ, H and K band near infrared (NIR) medium resolution spectroscopy (R ~ 3500). Targets are selected from a 7.2' diameter patrol field. Ultra-deep spectroscopy of ~ 80 early-type cluster galaxies (~ 20hr on source) and ~ 200 (~ 10hr on source) early-type field galaxies at 1 < z < 2 will dramatically improve the situation at z > 1 for which measurements of stellar velocity dispersions and absorption indices are limited to a few, often relatively young passively evolving galaxies (e.g. Bezanson 2013). In ESO Periods P92 and P93, 15 nights worth of data has been collected for KMOS-Clusters and 6 nights for VIRIAL: this will be supplemented with more data in upcoming semesters. All galaxies have multiband HST imaging including existing or upcoming WFC3 IR imaging, providing stellar mass maps and sizes. Combined with our dispersion measurements, this will allow us to examine the fundamental plane and the dynamical mass of a large sample of z > 1 galaxies for the first time, for both cluster and field galaxies.

  16. Characterization of Salmonella isolated from captive and free-living snakes in Germany.

    PubMed

    Krautwald-Junghanns, Maria-Elisabeth; Stenkat, Julia; Szabo, Istvan; Ortlieb, Falk; Blindow, Irmgard; Neul, Ann-Kathrin; Pees, Michael; Schmidt, Volker

    2013-01-01

    Reptiles are well-known reservoirs of Salmonella spp. and cases of reptile-associated salmonellosis (RAS) are increasing since reptiles are becoming more popular as pets. In the present study, the presence, distribution and prevalence of serovars of Salmonella was investigated in captive snakes (n = 87) and in free-living snakes (n = 87) in Germany. A total of 43 S. enterica-isolates were recovered from organ samples and cloacal swabs, predominantly belonging to the subspecies diarizonae (IIIb) (n = 27), enterica (I) (n = 7) and houtenae (IV) (n = 6). S. enterica subsp. enterica (I) serovar Paratyphi B (n = 4) and S. enterica subsp. diarizonae (IIIb) serovar 47:l,v:z (n = 3) were the most frequently isolated serotypes. Nevertheless, the fact that most serotypes were only represented by a single isolate points out the high diversity of Salmonella present among snakes. Salmonella enterica subsp. diarizonae (IIIb) serotype 40:i:z53, which was isolated twice from two free-living Eurasian adders (Vipera berus) captured at different locations, has not been previously described. Our results confirm the role of both free-living and captive snakes as reservoirs of S. enterica in Germany.

  17. Geographic List of Prime Contract Awards. Oct 91 - Sep 92. FY92. (Dolton Illinois - Vanlear Kentucky)

    DTIC Science & Technology

    1993-01-01

    q4N4 11 "N(󈧰 0 ( In N" -4 II 10-40 I ,LZ2 22zz222zz22z222222222222222 2 Z 2of I WOO) II IJIZ 112222>-Z>->-ZZZZZZZZZ2Z)-Z2)-2-2>- V41 Z 2 Ga *in2 iI...CI) 0) N on 4-a 0-40 I, ZZ 2 2 2 Z 22 2 z 2 2 2 I, to ( )00) z ga FZZ nZ b to u4 ,nZ vsZZ us= 901 U)2 44 n Az * 40 000 54. .- 4 ’.4 -4 .1 4 ’- - . . I...z z z zzzz z z z z CZ0 CZO OZO A Ia in o co if CO 00 MIM Ga ca11 1 a c. 1- 11 c, < < 0 << o<< c)<<< 0 < 4 1 inow of zz zz zzzz zz zzz z zz zoil I OQU

  18. Prime Contract Awards by Region and State, Fiscal Years 1981, 1982, 1983.

    DTIC Science & Technology

    1983-01-01

    Z w 0 3 - - ( 40.10 W-- o >10 -2 iI DW0 W00 .On 0.00.In U)ZI 000.1 - 1D -1- 00 11.00100a. 10nX0.DO 0 1- 0 ZOIO) .- I- w >a( a -L0.( -1 w:4: w-0.. 1002...4 o 0 42CDC 0 02 - -2 C) < :-). .w 4 nwo4 00 IL -i 0 V0. 1 0 42: -1 0 01 I D WI 0 0-L wI to)W 0- Wt-(4 s E4La K L..U ! 0 - l..1-2 a- 1D 42:41Z W 4 44 J...EE - C z 10 z CLCC 1 CU(n zIz A z r T cc LO IX. 4- j 0 a 0-0 -Z 0) V)JZC 0 )azaz z tq : Ca C aCa W A. J00 * .J W .4 U-zZO O - EZW LWCa: W V) W

  19. Dollar Summary of Prime Contract Awards by State, County, Contractor and Place. Part 4 (Montgomery-Weston)

    DTIC Science & Technology

    1990-01-01

    I.WMi I GO I co ’Co lGa I I .g o "oc taa smMm E 2 IC )-I 0, W04= L-U A C 0 41 -.- C % . , 0 c I - . - z I >- IL I La. aL 00 Ezw 0 W- Ow 41. uj a I-9 t...34 2 2 2 -4z0 424. 0. I 2l I xx << W CK ZIL I.Rw L z ww 0ww0 w0 (0Z I- 30 ~ C C 0 OO 0Ze C fo I I in6 1D t 0L 4 - in 0C)c Dc r I& U)10 I I. L i 4 CK... 1D L-). IL 00L -U-L~ I0 CL-9 I.- "CUC 9ow I- 004 915)9 (0z 9J x 948o--iz0 0 0-O " 43 -a I" I<C zdw " 0 I -I (0. I " 9 I 04 ~~ I * J WM I UW . . 9 L. LL

  20. Air Force Office of Scientific Research Technical Report Summaries: October - December 1990

    DTIC Science & Technology

    1990-12-01

    L- N : ini -04 I 0))44 0 -- 4 I- 0 0-WIn4 - D. N -- 0 C 4 0 ) 04 0. < l’ - .. 0 41 1D 0) (0’ 0. . <’ U) 4- M < ir I X 0 .0- ’ 0 ɜ-1C-’ 0 Lu 0 Lu 1 0...0 -MC WO UO-10- L’--VD4 -- 0 C’ IZ LE u )4,a C 0C, 7- 0 -;.i.0C~ N 104 1 MtnC C L tn ",- 010 > < z 0 c M: 3 ; - D CLU-4) a - - OC -V 1D 0 Z .- E.-10...Cl’ ix0 10 -- m u o .- c- u -1>- *ZWU = D: 4n -m a) 0 Wn 4-W0 --In -- -z 0 ixI 0 z Z -0 0 0) 0 -01 L.C M MC 0oCL 0W-.-~0 f- Z I U- LbX. (I.00 1D U m

  1. Dollar Summary of Prime Contract Awards by State, Place, and Contractor, FY 86. Part 1. (Aliceville, Alabama - Washington, DC).

    DTIC Science & Technology

    1986-01-01

    04 L 010 z 0 C󈧭 - co - 0) 0 0 N 140 k.- -L& - z 0 (n C40w 0I > 1D OCL/)014)( -. z Lmn ’ I L.J . I r4I 01 40N >~ m ~ EC uo ci wl Ln 0fl TIu.r V) ~ 4 1...OZWF- W<aoo0OzC 9 9 z >-ZzzzzI-40 4UUI-9o0 44400w .... 09I0000U.w-(/)9-044444 90 9 9-44j r-41 0 Z SOr I 1 ’ ~0 f-- 1D I J lr.- 00 i 14014 zr >- )-l Mf...o4 WO0 -i ID -) x 4) 1D ~ wow mnoD 0"- 01 x LAo-O~ aInn E Iz 1- w w i . 0 2- < L..X 1-01 <. lnOr-Izz on Zw -0 I-I I0 01- 040 _-i I 0-1I - 0 Dx "l4o

  2. Source Header List. Volume 2. L through Z

    DTIC Science & Technology

    1998-07-01

    WO WU W uWU. WI1- 4 z W .( 4 > Z U 4 Z - 1D I- 4 I-U I- <I-0 I-Z I- I- I-x W 4 W Win 4 3 01M 0 HU4 HH HO " ~ H4 H" H H-. HO U IX WC M I - I-. in ZH...w- z M i i WED Ji m. U 4 D wWmEV w 0- 8 -1 W>0 ( z z u A0 :3l m-U 0 ED 1D 2D2 I- O w "--. ’- iD u’ u )En 44( C) mD ED ED ED LI ED Mi - i W 0 0 .I- 0-I...Nl co 10 C0 0) In 0 10 Cl 02) r- V * - 00 10 - 10 q Cl c0 V 10 C0 1- 10 co 1 r- U N 02) 02)0 M2 020 CV)Nl M2 1D 10 02) c 0 M2 Nl 10 N M 00 1- u z U 2

  3. Programming standards for effective S-3D game development

    NASA Astrophysics Data System (ADS)

    Schneider, Neil; Matveev, Alexander

    2008-02-01

    When a video game is in development, more often than not it is being rendered in three dimensions - complete with volumetric depth. It's the PC monitor that is taking this three-dimensional information, and artificially displaying it in a flat, two-dimensional format. Stereoscopic drivers take the three-dimensional information captured from DirectX and OpenGL calls and properly display it with a unique left and right sided view for each eye so a proper stereoscopic 3D image can be seen by the gamer. The two-dimensional limitation of how information is displayed on screen has encouraged programming short-cuts and work-arounds that stifle this stereoscopic 3D effect, and the purpose of this guide is to outline techniques to get the best of both worlds. While the programming requirements do not significantly add to the game development time, following these guidelines will greatly enhance your customer's stereoscopic 3D experience, increase your likelihood of earning Meant to be Seen certification, and give you instant cost-free access to the industry's most valued consumer base. While this outline is mostly based on NVIDIA's programming guide and iZ3D resources, it is designed to work with all stereoscopic 3D hardware solutions and is not proprietary in any way.

  4. Word Criticality Analysis. MOS: 16B. Skill Levels 1 & 2

    DTIC Science & Technology

    1981-09-01

    COMMAND FORT MONROE, VIRGINIA 23651 - A-9 1916 A., ’F 41 IIL SEQUJENTIAL CATA AGE 4 A’~~s~ ,~.. ~ AG 1C 2 TYPE MEORO By-. S5 ANC ~,(f A ZA’I’L Y elt *4...il #1 1l, 13. 1)1 1.;, IC , !. 1 !*2,t Ict ’. 9201 96,V1 - 95, 9C92 es.* 64. ,. 6z[*4 ’-.’ !9,1 !6,1. T.1 61o 669. 659. -.,1 %, 55, 56p: 45.1 4, 47.2...4 SliEL 57.1 let! 4 S t - Y-S fE P lot 4 SHV-r 2)01 4 ST i.Z. ).h. 4 ’ I.ACI 7t- 4 S)C’ 1s 1 98.gl 7.1 4 sIrf.. E !#I 141.1 UN3.1 4 sc i C,± ict

  5. Functional calculus using wavelet transforms

    NASA Astrophysics Data System (ADS)

    Holschneider, Matthias

    1994-07-01

    It is shown how the wavelet transform may be used to compute for a function s the symbol s(A) for any (not necessarily) self-adjoint operator A whose spectrum is contained in the upper half plane. For self-adjoint operators it is shown that this functional calculus coincides with the usual one. In particular it is shown how the exponential eitA can be written in terms of the resolvent Rz=(A-z)-1 of A as follows: eitA=(1/c) ∫0∞da an-2∫-∞+∞ dbĝ¯ (at)eitbRb-ian(A), with c=-2iπ×∫0∞(dω/ω) (-iω)n-1ĝ¯(ω)e-ω, and n∈N, and the integral is understood as the Cesaro limit. This shows explicitly how the behavior for large t is determined by the behavior of Rz at Iz ≂1/t.

  6. A User’s Manual for a Computer Program to Generate Fatigue Spectrum Loading Sequences

    DTIC Science & Technology

    1978-11-01

    00000C 0=130 0000 000 e0 00 DD oD 003*JD oII) I CC u* LL Lux -0. C L/)Vza: Li Cc UJ U- 0 LL.) uj - 4LI 0 C LU ILU V < LL) W e- 0 -u LI- 0 ’ . D2 arU...L> LUX -4LL - LL (.) UJZ 𔃾)- ZV) < 9- A U) - x 7 z &U -CULL I- ZW -j0 0 W4X ZU 𔃺 (.D- -CX C 0 LL U -0 0 4 WUtmuL w on 0’-UD -JZZ ,-" m U+ (Z VWW...JXO- -4).CU W LLJWcmin AZ~u~~ )< 2’- - ~ -It 00 c~Z-4 *.-Z- 87 oooo.1oooOooooo W-O OO OO I.-Z’~~ -LILJ < ULL ODI--ix I- dIC 0- aL wj 0- < w:3 x ’ cc X

  7. Fourier series and {delta}-subharmonic functions of finite {gamma}-type in a half-plane

    SciTech Connect

    Malyutin, K G

    2001-06-30

    Let {gamma}(r) be a growth function and let v(z) be a proper {delta}-subharmonic function in the sense of Grishin in a complex half-plane, that is v=v{sub 1}-v{sub 2}, where v{sub 1} and v{sub 2} are proper subharmonic functions (limsup{sub z{yields}}{sub t}v{sub i}(z){<=}0, for each real t, i=1,2), let {lambda}={lambda}{sub +}-{lambda}{sub -} be the full measure corresponding to v and let T(r,v) be its Nevanlinna characteristic. The class J{delta}({gamma}) of functions of finite {gamma}-type is defined as follows: v element of J{delta}({gamma}) if T(r,v){<=}A{gamma}(Br)/r for some positive constants A and B. The Fourier coefficients of v are defined in the standard way. The central result of the paper is the equivalence of the following properties: (1) v element of J{delta}({gamma}); (2) N(r){<=}A{sub 1}{gamma}(B{sub 1}r)/r, where N(r)=N(r,{lambda}{sub +}) or N(r)=N(r,{lambda}{sub -}), and |c{sub k}(r,v)|{<=}A{sub 2}{gamma}(B{sub 2}r). It is proved in addition that J{delta}({gamma})=JS({gamma})-JS({gamma}), where JS({gamma}) is the class of proper subharmonic functions of finite {gamma}-type.

  8. Manuscript "Collection of Solved Problems of General Astronomy" by Vojislav Miskovic

    NASA Astrophysics Data System (ADS)

    Pejovic, N.

    2009-09-01

    In this paper we present the first university problems book concerning astronomy written in Serbian. The topic is "Zbirka rešenih zadataka iz opšte astronomije" (A Collection of Solved Problems of General Astronomy) by Prof. Vojislav Mi\\vsković. The first part of this collection was published in 1956 in Belgrade. The second one is still in the form of a manuscript. Though completely prepared for publishing, it has never been published. From the methodical point of view the collection was interestingly and nicely arranged. All astronomical notions and formulae are treated in details and well explained so that no complementary textbook is needed. A special attention is devoted to the numerical solution of the problems, which is not only missing in Serbian schools, but also, as said by Mi\\vsković in the Preface, is not properly valued. This paper treats both parts of this Collection which have been digitized and are available in the Virtual Library of the National Digitization Centre (Virtual Library, http://elib.matf.bg.ac.yu:8080/virlib/). By means of the manuscript digitization the second part of the Collection has become available to public use.

  9. Occurring mechanism and restraining method research of numerical noise signal in penetration simulation

    NASA Astrophysics Data System (ADS)

    Wang, Chen; Wang, Yabin

    2016-09-01

    In hard target penetration simulation, the existing researches of the convergence of results are mainly concentrating in the corresponding relationship between penetration depth and mesh scales. However, the influence of the mesh difference on the penetration resistance and acceleration signals are seldom refer to. This paper presents the occurring mechanism and restraining method of numerical noise signal in penetration simulation. First, the concept of the noise signal izs proposed. By taking a 3D penetration simulation as example, the influence of the noise signal on the penetration resistance in different mesh scales and impact velocity is studied. To ensure the convergence of the computational results, the grid scale of the target is encrypted to 1:1:8. In addition, modern spectrum analysis method is introduced to further analyze the penetration resistance signal. The research results presented is useful to improve the computational accuracy of high speed projectile penetration simulation, and provide important reference for carrying out structural design and optimization of fuze system.

  10. Transmission Monitoring and Control (TRAMCON) Segmentation Plan for the DCS (Defense Communications System) Digital Transmission Network.

    DTIC Science & Technology

    1985-03-11

    1111It 1101 11 .11 11 11 1 1 1 w F 0 04M34 193.4 0 340 13 it 111111 1 C 1 1111It1It 111111111 I 1 111a 1- - p 1 3 3 F - 0 1 1 1 I 1 11111 1 1 11 1 11 1 1 11...4444 ..4 0 1 . f .4 .4 4...444 . .49 4 C0 01-00 11 11 11 I W11 1 4 1 1 II I 1 1 1 030 %a 033 a li1111111i I II I I1 1 I I111 II I I1 - 1-0 319 .3zN- I...Z 0 9K N t.. -0 It s11 11 t1 1 1 1 II1 1 1 C1 CI, a I I N NC4 4 4 NN N .4..4..4.44 nV f 0I U IIm a% 0% a% U3 w ) W343 I C- I c. - -444 44 44c44 4c

  11. All Prime Contract Awards by State or Country, Place, and Contractor, FY 87. Part 16. Aberdeen, North Carolina-Youngstown Municipal, Ohio.

    DTIC Science & Technology

    1987-01-01

    ZN0 20e <NN’(J 0 ’ 0 Ul 00I 0 000000(00100000000 .- 000 00 Un ŔN0(0040 0 C4 I C4 Mill . Z ZZ Z Z ZZ 2 Z Z ’ 2 P43 . In In C (q -4 In 0 0 NW-40n a3 In...0 0 -4 w --4 01K0 -4 1-4 4 h 0 s4 4 -(A >u -- MILL -4-4 -4 -4-4 03L I.-LA 0 in YLA 40 >LA XO 4n U- ON II -- -J Z 2c 0 wa Us 0rw< -C s -4101Z4...40 XN r4?- -0 ILN NNNNNNN-N-P-t-N- NNP. NNNP NN r r ? r (A I 0o -4 Iz 0 2-4 w m 000 "-4505 00 I-IL. uL nu nL nuit 055555555in n ) i wi vn I- 4ION ON

  12. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 10 (Germer Equipment Co-Hamilton Hilton National Wembley)

    DTIC Science & Technology

    1990-01-01

    It Coo it z z zzz z z z z z z z zzzzz If I Inkn ISO 0 0 -0 10 0 C> 0 C. 0 If I C-*W to 11 1 0 * LAJ 11 to I In -* Lo.1 So if I 0q*0 it 114...0 0 0> 341 i I(0 " iZ 0) 0> 0 ᝻ 1IM N 110 0D 0 N I (0"J AZU- 1.- 0 IT )l(N ISO . 0) 0) < C)I11E I mc,4 Il L. 00 00 x w 11 4 II I -l t- InCio (oNc it...0) 0) 00 0 00 <u i<o co 4 (C (D (D(D <I ico 1 4-DI 4~,1- 40 1- -1 N m 3li I0CoN It 0 -.1 C 00000 < iso Io m" 1] 1- U) 4)- w o0o00coo0oo0 Cdi Mlico 11

  13. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 8 (Electronic Design Inc-Florida North Shipyards)

    DTIC Science & Technology

    1990-01-01

    0000 00 00 000000c00 00 00 00c00 00 000000 00 00 0000 0 ISO I) 1 0 MCC 1 (( Iuc n Mr 0C1(1M L-.- I rC-4 -- 4 -- 4 -- 4 -- 4 -- 4 -4-4-4-4 -4 -4-4 -A-4...C4 i I វ’) of0 l--4-.4- (04 4 1 0 ( 14 N oo I0 1 <N " I if 4 In cr- on to (r-N(14mulIn(Dr--0000 )- -c,4m < 4< -I -f 0)4 Iz 0) 1 (0 I 1 00 ISO I ’XN...to 00 a (00 Ulf N 00( 0) 1 In(D( In -4 ) Kr-A-4- ISO . (uu M 000 rI -4 4 -4 C4 00 0) C1) NI-4 -4 4 -4 -4 III(0 S -4 In C1) C4 ’ 00 0 tH o co00 I - .T

  14. A Dark Energy Camera Search for an Optical Counterpart to the First Advanced LIGO Gravitational Wave Event GW150914

    SciTech Connect

    Soares-Santos, M.

    2016-05-27

    We report initial results of a deep search for an optical counterpart to the gravitational wave event GW150914, the first trigger from the Advanced LIGO gravitational wave detectors. We used the Dark Energy Camera (DECam) to image a 102 deg$^2$ area, corresponding to 38% of the initial trigger high-probability sky region and to 11% of the revised high-probability region. We observed in i and z bands at 4-5, 7, and 24 days after the trigger. The median $5\\sigma$ point-source limiting magnitudes of our search images are i=22.5 and z=21.8 mag. We processed the images through a difference-imaging pipeline using templates from pre-existing Dark Energy Survey data and publicly available DECam data. Due to missing template observations and other losses, our effective search area subtends 40 deg$^{2}$, corresponding to 12% total probability in the initial map and 3% of the final map. In this area, we search for objects that decline significantly between days 4-5 and day 7, and are undetectable by day 24, finding none to typical magnitude limits of i= 21.5,21.1,20.1 for object colors (i-z)=1,0,-1, respectively. Our search demonstrates the feasibility of a dedicated search program with DECam and bodes well for future research in this emerging field.

  15. X-ray line emission from highly ionised argon and sulphur in tokamak plasmas

    NASA Astrophysics Data System (ADS)

    McGinnity, Paul

    Observations of H-like and He-like argon line emission and associated satellite spectra have been made on the JET (Joint European Torus) tokamak by a Bragg rotorspectrometer and a double crystal monochromator. Similar He-like sulphur measurements have been made on the COMPASS-D (Compact Assembly) tokamak by a Johann curved crystal spectrometer. Recently calculated electron impact excitation rates for He-like ions were used in the derivation of the electron temperature sensitive line ratio G=(Ix+Iy+Iz)/Iw and the electron density sensitive ratio R=Iz/(Ix+Iy), where w, x, y and z are the He-like resonance line, intercombination lines and forbidden line respectively. For S XV the ratios Ik/Iw and Iq/Iw were also calculated, where k and q are Li-like dielectronic satellites to the w line formed by dielectronic recombination and inner shell excitation respectively. Both are electron temperature dependent, the latter also being sensitive to changes in the ionisation balance. The fine structure ratios Ix/Iy and /beta = Ly/alpha 2/Lyα1 were calculated for He-like S XV and H-like Ar XVIII respectively, where Ly/alpha/sb[1,2] are the fine structure components of the H-like Lyman alpha line. Transport modelling was carried out to account for non-coronal conditions in the JET plasma while a near-coronal equilibrium was assumed in the COMPASS-D plasma. Calculated ratios were compared with experimental measurements obtained from JET and COMPASS-D. For higher temperatures, such as during additional heating, the Ar XVII emission shell was found to move of axis, with a subsequent reduction in the G ratio. For S XV good agreement with calculations was found between the measured G and Iq/Iw ratios, indicating that the assumption of near-coronal equilibrium was valid. Lower than expected values of the S XV R ratio were found. After investigation of the atomic physics processes it was concluded that this was due to an unidentified instrumental effect of the Johann spectrometer. An

  16. Expression of Cyclin d1 protein and CCND1 та PNKP genes in peripheral blood mononuclear cells in clean up worker of Chornobyl accident with different state of immune system.

    PubMed

    Bazyka, D A; Kubashko, A V; Ilyenko, I M; Belyaev, O A; Pleskach, O J

    2015-12-01

    Meta. Doslidyty zminy rivniv Cyclin D1+ klityn ta asotsiyovanykh geniv CCND1 ta PNKP u mononuklearakh peryfe rychnoI krovi v uchasnykiv likvidatsiI naslidkiv avariI (ULNA) na ChAES z riznym imunnym statusom v zalezhnosti vid dozy oprominennia.Materialy i metody. Proanalizovano vidnosnyy riven' Cyclin D1+ klityn u mononuklearakh peryferychnoI krovi 39 ULNA na ChAES, cholovikiv, oprominenykh u dozi u diapazoni (0,01–2,00) Gr. Imunologichnyy status obstezhenykh vyz nachavsia za rivnem CD3/19, CD4/8, CD3/HLA DR, SD3/16/56 metodom protochnoI tsytofluorymetriI ta za vmistom Ig klasiv A,M,G metodom imunofermentnogo analizu u krovi. Ekspresiia geniv CCND1 ta PNKP, iaki pov’iazani z Syclin D1, provodylos' za metodom polimeraznoI lantsiugovoI reaktsiI u real'nomu chasi. Porivniannia rezul'tativ zdiysniuva los' iz vidpovidnymy danymy, otrymanymy vid 18 zdorovykh cholovikiv, iaki ne maly kontaktu z ionizuiuchym vyp rominiuvanniam vyshche pryrodn'ogo fonu.Rezul'taty. Pokazano, shcho vidsotok Suclin D1+ klityn zbil'shuiet'sia za normu v osib, oprominenykh u dozi > 0,1 Gr, ta koreliuie z dozoiu oprominennia (rs = 0,417, p = 0,048). Vidkhylennia rivnia Cyclin D1+ klityn za mezhi kontrol'nykh zna chen' pov’iazuiet'sia zi zminamy v klitynniy ta gumoral'niy lankakh imunitetu. Zmenshennia vidsotku Cyclin D1+ klityn za mezhi kontrol'nykh znachen' v ULNA na ChAES iz dozoiu < 0,35 Gr suprovodzhuiet'sia znyzhenniam rivniv CD3+ ta pidvy shchenniam CD3 16+56+ limfotsytiv; u osib, oprominenykh u dozi > 0,35 Gr, zbil'shennia vidsotku Cyclin D1+ klityn asotsiiuiet'sia zi znyzhenniam CD3+ ta tendentsiieiu shchodo znyzhennia CD3+16+56+ limfotsytiv u poiednanni zi zbil'shen niam rivnia IgG. Zbil'shennia rivniv CD4+, CD19+, Ireg. ta IgG suprovodzhuiet'sia poiavoiu koreliatsiynykh zv’iazkiv mizh Cyclin D1+ ta CD3 16+56+ klitynamy (rs = 0,872, p = 0,049), Cyclin D1+ ta CD8+ i IgG (rs = 0,683, p = 0,042; rs = 0,809, p = 0,014), Cyclin D1+ ta CD4+ (rs = 0,602, p = 0,029), Cyclin D1+ ta CD19+ i

  17. Vestibular and acustic dysfunctions in clean up workers of Chornobyl accident (30 years of follow up).

    PubMed

    Zabolotnyi, D I; Mishchanchuk, N S

    2016-12-01

    Meta – vyvchyty kliniko elektrofiziologichni porushennia pry vestybuliarniy̆ ta akustychniy̆ dysfunktsiiakh v uchas nykiv likvidatsïï naslidkiv avariï na Chornobyl's'kiy̆ atomniy̆ elektrostantsiï v zalezhnosti vid dozy ta tryvalosti diï ionizuiuchoï radiatsiï, osoblyvosti determinovanykh efektiv vprodovzh 30 rokiv pislia avariï.Material ta metody. U 7812 uchasnykiv likvidatsiï naslidkiv avariï na ChAES (ULNA na ChAES) cholovichoï stati, u to mu chysli u 325 osib, vidibranykh dlia prolongovanykh doslidzhen', u 1986 2015 rr. provedeni standartni kliniko elektrofiziologichni obstezhennia funktsiy̆ vestybuliarnogo ta akustychnogo analizatoriv. Vykonani matematychni metody analizu iz zastosuvanniam programnykh paketiv SYSTAT, EPICURE ta EGRET.Rezul'taty. Vstanovleni vestybuliarna ta akustychna dysfunktsiï za tsentral'nym typom z progresuiuchym rozvyt kom gal'mivnykh protsesiv u stovburomozkovykh, pidkorkovo korkovykh strukturakh vestybuliarnogo ta akustychnogo analizatoriv. Vyznachena zalezhnist' zmin u tsykh strukturakh vid velychyny dozy ta tryvalosti diï ionizuiuchoï radiatsiï. Vstanovleni zakonomirnosti determinovanykh radiatsiy̆nykh efektiv u vzaiemozv'iazku z formuvanniam or ganichnoï tserebrovaskuliarnoï patologiï v ULNA na ChAES u viddaleni pisliaavariy̆ni roky, iaki uzgodzhuiut'sia z ney̆ rofiziologichnymy, MRT ta inshymy obstezhenniamy, shcho pidtverdzheno pry koreliatsiy̆nomu analizi.Vysnovky. Vidznacheno, shcho vestybuliarna ta akustychna dysfunktsiï v ULNA na ChAES proiavliaiut'sia kliniko elekt rofiziologichnymy zminamy na rivni tsentral'nykh struktur doslidzhuvanykh analizatoriv, iaki vkazuiut' na para lelizm spil'nogo mekhanizmu determinovanykh radiatsiy̆nykh efektiv pry dozi 0,20 Gr,a takozh ïkh dozozalezhnist' u dy namitsi 30 pisliaavariy̆nykh rokiv. Vstanovleno, shcho vestybuliarna dysfunktsiia v ULNA na ChAES proiavliaiet'sia klinichno ranishe, a elektroakustychni ta elektrofiziologichni zminy pry

  18. Dynamic secondary ion mass spectrometry and X-ray photoelectron spectroscopy on artistic bronze and copper artificial patinas

    NASA Astrophysics Data System (ADS)

    Balta, I. Z.; Pederzoli, S.; Iacob, E.; Bersani, M.

    2009-04-01

    To prevent the natural processes of decay and to develop and improve the treatments of conservation and restoration of artistic bronzes meaning statues and sculptures, it is important understanding the patination processes and the knowledge of artificially corroded surfaces. Chemical and physical characterization of artificial patinas obtained on artistic bronzes and coppers by using the 19th century Western traditional patination techniques and recipes by means of SEM-EDS, light microscopy and ATR/FT-IR has been done in previous studies [I.Z. Balta, L. Robbiola, Characterization of artificial black patinas on artistic cast bronze and pure copper by using SEM-EDS and light microscopy, in: Proceedings of the 13th European Microscopy Congress, 22-27 August 2004, Antwerp, Belgium, EMC 2004 CD-Rom Conference Preprints; I.Z. Balta, L. Robbiola, Traditional artificial artistic bronze and copper patinas—an investigation by SEM-EDS and ATR/FT-IR, in: Proceedings of the 8th International Conference on Non Destructive Investigations and Microanalysis for the Diagnostics and Conservation of the Cultural and Environmental Heritage, 15-19 May 2005, Lecce, Italy, ART'05 CD-Rom Conference Preprints]. Differences in morphology (structure, thickness, porosity, adherence, compactity, uniformity, homogeneity) and also in composition, on both artistic cast bronze and pure copper patinas, were clearly evidenced. Further in-depth investigation is required to be carried out in order to better understand the patinas mechanisms of formation and the layers kinetics of growth. The elemental and chemical analysis, either on a surface monolayer or in a depth profile, by using the Secondary Ion Mass Spectrometry (SIMS) and X-ray Photoelectron Spectroscopy (XPS) techniques, can provide this kind of information, unique at trace-level sensitivity. SIMS has proved to be a suitable analytical technique for analyzing small amounts of material with high atomic sensitivity (ppm or even ppb) and high

  19. A numerical investigation of phytoplankton and Pseudocalanus elongatus dynamics in the spring bloom time in the Gdańsk Gulf

    NASA Astrophysics Data System (ADS)

    Dzierzbicka-Głowacka, Lidia

    2005-01-01

    A nutrient-phytoplankton-zooplankton-detritus (1D-NPZD) `phytoplankton {Phyt} and Pseudocalanus elongatus {Zoop} dynamics in the spring bloom time in the Gdańsk Gulf. The 1D-NPZD model consists of three coupled, partial second-order differential equations of the diffusion type for phytoplankton {Phyt}, zooplankton {Zoop}, nutrients {Nutr} and one ordinary first-order differential equation for benthic detritus pool {Detr}, together with initial and boundary conditions. In this model, the {Zoop} is presented by only one species of copepod ( P. elongatus) and {Zoop} is composed of six cohorts of copepods with weights ( Wi) and numbers ( Zi); where Zoop= limit∑i=16W iZ i. The calculations were made for 90 days (March, April, May) for two stations at Gdańsk Gulf with a vertical space step of 0.5m and a time step of 900 s. The flow field and water temperature used as the inputs in the biological model 1D-NPZD were reproduced by the prognostic numerical simulation technique using hydrographic climatological data. The results of the numerical investigations described here were compared with the mean observed values of surface chlorophyll- a and depth integrated P. elongatus biomass for 10 years, 1980-1990. The slight differences between the calculated and mean observed values of surface chlorophyll- a and zooplankton biomass are ca. 10-60 mg C m -3 and ca. 5-23 mg C m -2, respectively, depending on the location of the hydrographic station. The 1D-NPZD model with a high-resolution zooplankton module for P. elongatus can be used to describe the temporal patterns for phytoplankton biomass and P. elongatus in the centre of the Gdańsk Gulf.

  20. A mutant of the nematophagous fungus Paecilomyces lilacinus (Thom) is a novel biocontrol agent for Sclerotinia sclerotiorum.

    PubMed

    Yang, Fan; Abdelnabby, Hazem; Xiao, Yannong

    2015-12-01

    Sclerotinia sclerotiorum causes severe stem rot and yield loss in oilseed rape (Brassica napus L.) and other crops worldwide. Extensive studies have been conducted on Paecilomyces lilacinus as a nematophagous bioagent. However, no reports stated the effect of P. lilacinus as a biocontrol agent against oilseed rape rot S. sclerotiorum. This study describes such effect in lab and field trials using the new transformant pt361 derived from the wild strain P. lilacinus 36-1. Unlike the wild-type strain, the mutant pt361 showed high antagonistic effect against S. Sclerotiorum A. Under lab conditions, the pt361 inhibited (65%) radial mycelial growth of S. sclerotiorum in dual culture test producing 5.9 mm inhibition zone IZ in front of the S. sclerotiorum colony. Moreover, the cell-free filtrate of pt361 culture showed strong inhibitory effects (60.3-100%) on mycelial growth of S. sclerotiorum. In leaf detached assay, pt361 significantly (p < 0.05) inhibited (40.4-97.9%) the extension of the leaf spots caused by S. sclerotiorum A at all tested concentrations. The genomic DNA sequences of the inserted T-DNA flanking obtained from pt361 strain was cloned, verified as a glycoside hydrolase 31 family by homologous analysis with other fungal strains, and named PGH31 (2556bp). Secondary structure prediction showed a domain (Glycoside hydrolase31). Three years field trial confirmed that the cell-free filtrates or spores suspension of pt361 achieved significant (p < 0.05) suppression of oilseed rape stem rot, promoted growth and increased yield compared to the control and exceeded, at dose 100%, the action of the fungicide procymidone(®). In conclusion, the mutant pt361 of P. lilacinus is a novel and promising biocontrol agent against oilseed rape Sclerotinia stem rot.

  1. Extragalactic circuits, transmission lines, and CR particle acceleration

    NASA Astrophysics Data System (ADS)

    Kronberg, Philipp P.; Lovelace, Richard V. E.

    2015-08-01

    A non-negligible fraction of a Supermassive Black Hole's (SMBH) rest mass energy gets transported into extragalactic space by a remarkable process in jets which are incompletely understood. What are the physical processes which transport this energy? It is likely that the energy flows electromagnetically, rather than via a particle beam flux. The deduced electromagnetic fields may produce particles of energy as high as ˜ 1020 eV. The energetics of SMBH accretion disk models and the electromagnetic energy transfer imply that a SMBH should generate a 1018 - 1019 Ampères current close to the black hole and its accretion disk. We describe the so far best observation-based estimate of the magnitude of the current flow along the axis of the jet extending from the nucleus of the active galaxy in 3C303. The current is measured to be I ˜ 1018 Ampères at ˜ 40 kpc away from the AGN. This indicates that organised current flow remains intact over multi-kpc distances. The electric current I transports electromagnetic power into free space, P = I2Z, where Z ˜ 30 Ohms is related to the impedance of free space, and this points to the existence of cosmic electric circuit. The associated electric potential drop, V = IZ, is of the order of that required to generate Ultra High Energy Cosmic Rays (UHECR). We also explore further implications, including disruption/deflection of the power flow and also why such measurements, exemplified by those on 3C303, are currently very difficult to make and to unambiguously interpret. This naturally leads to the topic of how such measurements can be extended and improved in the future. We describe the analogy of electromagnetically dominated jets with transmission lines. High powered jets in vacuo can be understood by approximate analogy with a waveguide. The importance of inductance, impedance, and other laboratory electrical concepts are discussed in this context.

  2. Variables that influence HIV-1 cerebrospinal fluid viral load in cryptococcal meningitis: a linear regression analysis

    PubMed Central

    2009-01-01

    Background The central nervous system is considered a sanctuary site for HIV-1 replication. Variables associated with HIV cerebrospinal fluid (CSF) viral load in the context of opportunistic CNS infections are poorly understood. Our objective was to evaluate the relation between: (1) CSF HIV-1 viral load and CSF cytological and biochemical characteristics (leukocyte count, protein concentration, cryptococcal antigen titer); (2) CSF HIV-1 viral load and HIV-1 plasma viral load; and (3) CSF leukocyte count and the peripheral blood CD4+ T lymphocyte count. Methods Our approach was to use a prospective collection and analysis of pre-treatment, paired CSF and plasma samples from antiretroviral-naive HIV-positive patients with cryptococcal meningitis and assisted at the Francisco J Muñiz Hospital, Buenos Aires, Argentina (period: 2004 to 2006). We measured HIV CSF and plasma levels by polymerase chain reaction using the Cobas Amplicor HIV-1 Monitor Test version 1.5 (Roche). Data were processed with Statistix 7.0 software (linear regression analysis). Results Samples from 34 patients were analyzed. CSF leukocyte count showed statistically significant correlation with CSF HIV-1 viral load (r = 0.4, 95% CI = 0.13-0.63, p = 0.01). No correlation was found with the plasma viral load, CSF protein concentration and cryptococcal antigen titer. A positive correlation was found between peripheral blood CD4+ T lymphocyte count and the CSF leukocyte count (r = 0.44, 95% CI = 0.125-0.674, p = 0.0123). Conclusion Our study suggests that CSF leukocyte count influences CSF HIV-1 viral load in patients with meningitis caused by Cryptococcus neoformans.

  3. Kinematics invariance in multi-directional complex movements in free space: effect of changing initial direction.

    PubMed

    Cheron, G; Draye, J P; Bengoetxea, A; Dan, B

    1999-04-01

    We investigated in normal human subjects the effect of changing the initial direction on the kinematic properties of figure '8' movement performed as fast as possible by the right arm extended in free space. To this end, the motion of the index finger was monitored by the ELITE system. The figure '8' movement was characterized by a complex tangential velocity profile (Vt) presenting 5 bell-shaped components. It was found that the temporal segmentation following Vt was not significantly different, whatever the initial direction of the movement. The decomposition of Vt into different velocity profiles with respect to vertical (3 phases, Iy-IIIy) and horizontal (5 phases, Iz-Vz) directions showed a significant relationship between the amplitude and the maximal velocity for all the different phases (except the IIy phase), which demonstrated a good conservation of the Isochrony Principle. However, we showed that the transition between the clockwise and counter-clockwise loop (inflection point) induced greater variability in the vertical velocity profile than in the horizontal one. Moreover, some parameters such as the maximal velocity of Iy and the movement amplitude of the last phases (IIIy and Vz) showed significant changes depending on the initial direction. A highly significant positive correlation was observed between the instantaneous curvature and angular velocity. This was expressed by a power law similar to that previously describe for other types of movement. Furthermore, it was found that this covariation between geometrical and kinematic properties of the trajectory is not dependent on the initial direction of movement. In conclusion, these results support the idea that the fast execution in different directions of a figure '8' movement is mainly controlled by two types of invariant commands. The first one is reflected in the 2/3 power law between angular velocity and curvature and the second one is represented by a segmented tangential velocity profile.

  4. Lifted linear phase filter banks and the polyphase-with-advance representation

    SciTech Connect

    Brislawn, C. M.; Wohlberg, B. E.

    2004-01-01

    A matrix theory is developed for the noncausal polyphase-with-advance representation that underlies the theory of lifted perfect reconstruction filter banks and wavelet transforms as developed by Sweldens and Daubechies. This theory provides the fundamental lifting methodology employed in the ISO/IEC JPEG-2000 still image coding standard, which the authors helped to develop. Lifting structures for polyphase-with-advance filter banks are depicted in Figure 1. In the analysis bank of Figure 1(a), the first lifting step updates x{sub 0} with a filtered version of x{sub 1} and the second step updates x{sub 1} with a filtered version of x{sub 0}; gain factors 1/K and K normalize the lowpass- and highpass-filtered output subbands. Each of these steps is inverted by the corresponding operations in the synthesis bank shown in Figure 1(b). Lifting steps correspond to upper- or lower-triangular matrices, S{sub i}(z), in a cascade-form decomposition of the polyphase analysis matrix, H{sub a}(z). Lifting structures can also be implemented reversibly (i.e., losslessly in fixed-precision arithmetic) by rounding the lifting updates to integer values. Our treatment of the polyphase-with-advance representation develops an extensive matrix algebra framework that goes far beyond the results of. Specifically, we focus on analyzing and implementing linear phase two-channel filter banks via linear phase lifting cascade schemes. Whole-sample symmetric (WS) and half-sample symmetric (HS) linear phase filter banks are characterized completely in terms of the polyphase-with-advance representation. The theory benefits significantly from a number of new group-theoretic structures arising in the polyphase-with-advance matrix algebra from the lifting factorization of linear phase filter banks.

  5. Effects of Al, Ga-DOPING on Transparent Conducting Properties of Amorphous ZnO-SnO2 Films

    NASA Astrophysics Data System (ADS)

    Moriga, Toshihiro; Nishimura, Yusuke; Suketa, Hiroshi; Murai, Kei-Ichiro; Nogami, Kazuhiro; Tominaga, Kikuo; Nakabayashi, Ichiro

    ZnOSnO2 thin films were deposited on glass substrates (Corning#1737) by DC magnetron sputtering. In this works, we examined a doping effect on a ZnO target on transparent conducting properties. ZnO:Al(4wt%), and ZnO:Ga(6wt%) targets were used for a dopant-free ZnO target. Substrate temperature was held at 250°C. The current ratio δ was defined as IZn/IZ+ISn (ZnO target current divided by the sum of ZnO and SnO2 target currents). Compositions of as-deposited films were changed with the current ratio δ. In the ZnO-SnO2 system, amorphous transparent films appeared over the range of 0.33≤δ≤0.73. On the other hand, in the ZnO:Al(4wt%)-SnO2 and ZnO:Ga(6wt%)-SnO2 systems, they appeared over the range of 0.20≤δ≤0.80 and 0.33≤δ≤0.80, ≤δ≤ respectively. The minimum resistivity of amorphous films was about 3.0×10-2 Ωcm for all the systems. Al, Ga doping effect on film resistivity was not clear very much. But optical transparencies were 80-90% in visible region, 10% higher than those of ZnO-SnO2 system at average. Optical band gap for the films with the same current ratio δ also was enhanced by the Al, Ga doping.

  6. Chromospheric activity properties and search for subdwarfs and extreme subdwarfs based on LAMOST stellar spectral survey

    NASA Astrophysics Data System (ADS)

    Zhang, Liyun; Pi, Qingfeng; Han, Xianming L.; Shi, Jianrong; Wang, Daimei; Luo, Ali; Zhang, Yong; Hou, Yonghui; Wang, Yuefei

    2016-04-01

    Big data obtained from a stellar spectroscopic survey carried out using the Large Sky Area Multi-object Fiber Spectroscopic Telescope (LAMOST, also known as Guo Shou Jing telescope) provide important information for studying chromospheric activity, variability of chromospheric activity, and chromospheric statistical properties, and for searching subdwarfs and extreme subdwarfs. Using as chromospheric activity indicator the Hα line, we detected 6391 active M stars among the 99741 stars in the M-star catalogue of the LAMOST survey. We also obtained the relationship between the fraction of active stars and the spectral types, which is consistent to previous results. We also studied the effects of activity on broadband photometric colors, and we did not see significant differences between active and inactive M stars. Using as spectroscopic molecular indicators the CaH123 and TiO5 lines, we found 1288 subdwarfs (including 120 active subdwarfs). We also found 15 extreme subdwarf (2 active extreme subdwarf) candidates. Our subdwarf candidates are slightly redder by about 0.05 mag in g-r compared with dwarfs using the g-r and r-i, and g-r and i-z color diagrams. Using our active M-star catalogue, we found that 898 stars exhibited Hα emission in at least two exposures (170 of them in at least three exposures). Among these 170 stars, 163 of them show variability in Hα emission on long timescales (more than 2.5 h). Furthermore, 34 stars show variability over short timescales (less than 2.5 h), and 29 actives show variability over both short and long time scales.

  7. Elliptical Galaxies at z=0 from Self-consistent Hydrodynamical Simulations: Comparison with Sloan Digital Sky Survey Structural and Kinematical Data

    NASA Astrophysics Data System (ADS)

    Sáiz, A.; Domínguez-Tenreiro, R.; Serna, A.

    2004-02-01

    We present results of an analysis of the structural and kinematical properties of a sample of elliptical-like objects (ELOs) identified in four hydrodynamical self-consistent simulations run with the DEVA code (Serna, Domínguez-Tenreiro, & Sáiz). Star formation has been implemented in the code through a simple phenomenological parameterization, which takes into account stellar physics processes only implicitly through the values of a threshold gas density, ρg,thres, and an efficiency parameter, c*. The four simulations operate in the context of a Λ cold dark matter cosmological model consistent with observations, resolve ELO mass assembly at scales up to ~=2 kpc, and differ in the values of their star formation parameters. Stellar masses, projected half-mass radii, and central line-of-sight velocity dispersions, σlos,0, have been measured on the ELO sample and their values compared with data from the Sloan Digital Sky Survey. For the first time in self-consistent simulations, a good degree of agreement has been shown, including the Faber-Jackson and the Dn-σlos,0 relations, among others, but only when particular values of the ρg,thres and c* parameters are used. This demonstrates the effect that the star formation parameterization has on the ELO mass distribution. In addition, our results suggest that it is not strictly necessary, at the scales resolved in this work, to appeal to energy sources other than gravitational (as, for example, supernovae feedback effects) to account for the structure and kinematics of large elliptical galaxies.

  8. Zeta potential response of human erythrocyte membranes to the modulators of Gardos channel activity under low rate β-radiation.

    PubMed

    Zhirnov, V V; Iakovenko, I N; Voitsitskiy, V M; Khyzhnyak, S V; Zubrikova-Chugainova, O G; Gorobetz, V A

    2015-12-01

    Tsel' raboty. Izuchenie reaktsii dzeta potentsiala (DP) membran éritrotsitov cheloveka pri modifikatsii aktivatorami i blokatorami funktsional'nogo sostoianiia Ca2+-zavisimykh kalievykh kanalov v pole radioizotopnogo izlucheniia 90Sr/90Y maloi moshchnosti.Materialy i metody. Éritrotsity poluchali iz donorskoi krovi. DP vychisliali po poluchennomu znacheniiu élektroforeticheskoi podvizhnosti kletok. V kletochnye suspenzii predvaritel'no vnosili issleduemye veshchestva, a zatem alikvoty rastvora 90Sr(NO3)2, chtoby poluchit' konechnuiu kontsentratsiiu 44,4⋅kBk⋅l-1.Rezul'taty. Radioizotopnoe izluchenie 90Sr/90Y (RI, 15 mkGr/ch) povyshaet absoliutnoe znachenie DP (DPab) membran éritrotsitov i ego deistvie iavliaetsia obratimym. Éto ukazyvaet na to, chto éffekt oposreduetsia neioniziruiushchei komponentoi RI. Dibutiril-tsAMF v diapazone kontsentratsii 1–100 mkM dozonezavisimo povyshaet DPab membran éritrotsitov, no RI ne usilivaet ego éffekt. Anaprilin v kontsentratsiiakh 10 i 100 mkM dozonezavisimo povyshaet DPab. Éffekt maksimal'noi kontsentratsii anaprilina (100 mkM) – snizhaetsia RI. Klotrimazol v diapazone kontsentratsii 0,1–10 mkM povyshaet DPab membran éritrotsitov otnositel'no kontrolia, togda kak ego maksimal'naia kontsentratsiia – snizhet, a minimal'naia – dostoverno ne vliiaet na étot pokazatel'. Deistvie klotrimazola na DP pri kontsentratsiiakh 10–100 mkM otmeniaetsia RI, no ne izmeniaetsia pri 0,1–1 mkM. Nitrendipin vo vsem diapazone kontsentratsii dozonezavisimo povyshaet DPab membran éritrotsitov, a RI usilivaet ego deistvie. Vyvody. 1. Dlia ioniziruiushchei komponenty radionuklidnogo izlucheniia sushchestvuet porog biologicheskogo deistviia na kletki, opredeliaemyi éffektivnost'iu ikh antioksidantnoi sistemy.2. Pri moshchnosti doz nizhe porogovoi deistvie radioizotopnogo izlucheniia oposreduetsia ego neioniziruiushchei komponentoi i iavliaetsia obratimym, a poétomu opredeliaetsia tol'ko v pole izlucheniia.

  9. The continuing story of SN IIb 2013df: new optical and IR observations and analysis

    NASA Astrophysics Data System (ADS)

    Szalai, Tamás; Vinkó, József; Nagy, Andrea P.; Silverman, Jeffrey M.; Wheeler, J. Craig; Dhungana, Govinda; Marion, G. Howie; Kehoe, Robert; Fox, Ori D.; Sárneczky, Krisztián; Marschalkó, Gábor; Bíró, Barna I.; Borkovits, Tamás; Hegedüs, Tibor; Szakáts, Róbert; Ferrante, Farley V.; Bányai, Evelin; Hodosán, Gabriella; Kelemen, János; Pál, András

    2016-08-01

    SN 2013df is a nearby Type IIb supernova that seems to be the spectroscopic twin of the well-known SN 1993J. Previous studies revealed many, but not all interesting properties of this event. Our goal was to add new understanding of both the early- and late-time phases of SN 2013df. Our spectral analysis is based on six optical spectra obtained with the 9.2 m Hobby-Eberly Telescope during the first month after explosion, complemented by a near-infrared spectrum. We applied the SYNAPPS spectral synthesis code to constrain the chemical composition and physical properties of the ejecta. A principal result is the identification of `high-velocity' He I lines in the early spectra of SN 2013df, manifest as the blue component of the double-troughed profile at ˜5650 Å. This finding, together with the lack of clear separation of H and He lines in velocity space, indicates that both H and He features form at the outer envelope during the early phases. We also obtained ground-based BVRI and g'r 'i'z' photometric data up to +45 d and unfiltered measurements with the ROTSE-IIIb telescope up to +168 d. From the modelling of the early-time quasi-bolometric light curve, we find Mej ˜ 3.2-4.6 M⊙ and Ekin ˜ 2.6-2.8 × 1051 erg for the initial ejecta mass and the initial kinetic energy, respectively, which agree well with the values derived from the separate modelling of the light-curve tail. Late-time mid-infrared excess indicates circumstellar interaction starting ˜1 yr after explosion, in accordance with previously published optical, X-ray, and radio data.

  10. Intrastrand G-U cross-links generated by the oxidation of guanine in 5'-d(GCU) and 5'-r(GCU).

    PubMed

    Crean, Conor; Geacintov, Nicholas E; Shafirovich, Vladimir

    2008-10-15

    It has been suggested that carbonate radical anions are biologically important because they may be produced during the inflammatory response. The carbonate radicals can selectively oxidize guanine in DNA and RNA by one-electron transfer mechanisms and the guanine radicals thus formed decay by diverse competing pathways with other free radicals or nucleophiles. Using a photochemical method to generate CO(3)(-) radicals in vitro, we compare the distributions of products initiated by the one-electron oxidation of guanine in the trinucleotides 5'-r(GpCpU) and 5'-d(GpCpU) in aqueous buffer solutions (pH 7.5). Similar distributions of stable end products identified by LC-MS/MS methods were found in both cases. The guanine oxidation products include the diastereomeric pair of spiroiminodihydantoin (Sp) and 2,5-diamino-4H-imidazolone (Iz). In addition, intrastrand cross-linked products involving covalent bonds between the G and the U bases (GCU) were also found, although with different relative yields in the 2'-deoxy- and the ribotrinucleotides. The positive-ion MS/MS spectra of the 5'-r(GpCpU) and 5'-d(GpCpU) products clearly indicate the presence of covalently linked G-U products that have a mass smaller by 2 Da than the sum of the G and U bases in both types of trinucleotides. The 5'-d(GCU) cross-linked product was further characterized by 1D and 2D NMR methods that confirm its cyclic structure in which the guanine C8 atom is covalently linked to the uracil N3 atom.

  11. Analysis of guanine oxidation products in double-stranded DNA and proposed guanine oxidation pathways in single-stranded, double-stranded or quadruplex DNA.

    PubMed

    Morikawa, Masayuki; Kino, Katsuhito; Oyoshi, Takanori; Suzuki, Masayo; Kobayashi, Takanobu; Miyazawa, Hiroshi

    2014-02-10

    Guanine is the most easily oxidized among the four DNA bases, and some guanine-rich sequences can form quadruplex structures. In a previous study using 6-mer DNA d(TGGGGT), which is the shortest oligomer capable of forming quadruplex structures, we demonstrated that guanine oxidation products of quadruplex DNA differ from those of single-stranded DNA. Therefore, the hotooxidation products of double-stranded DNA (dsDNA) may also differ from that of quadruplex or single-stranded DNA, with the difference likely explaining the influence of DNA structures on guanine oxidation pathways. In this study, the guanine oxidation products of the dsDNA d(TGGGGT)/d(ACCCCA) were analyzed using HPLC and electrospray ionization-mass spectrometry (ESI-MS). As a result, the oxidation products in this dsDNA were identified as 2,5-diamino-4H-imidazol-4-one (Iz), 8-oxo-7,8-dihydroguanine (8oxoG), dehydroguanidinohydantoin (Ghox), and guanidinohydantoin (Gh). The major oxidation products in dsDNA were consistent with a combination of each major oxidation product observed in single-stranded and quadruplex DNA. We previously reported that the kinds of the oxidation products in single-stranded or quadruplex DNA depend on the ease of deprotonation of the guanine radical cation (G•+) at the N1 proton. Similarly, this mechanism was also involved in dsDNA. Deprotonation in dsDNA is easier than in quadruplex DNA and more difficult in single-stranded DNA, which can explain the formation of the four oxidation products in dsDNA.

  12. Weighing Neutrinos with Cosmic Neutral Hydrogen

    NASA Astrophysics Data System (ADS)

    Villaescusa-Navarro, Francisco; Bull, Philip; Viel, Matteo

    2015-12-01

    We investigate the signatures left by massive neutrinos on the spatial distribution of neutral hydrogen (H i) in the post-reionization era by running hydrodynamic simulations that include massive neutrinos as additional collisionless particles. We find that halos in massive/massless neutrino cosmologies host a similar amount of neutral hydrogen, although for a fixed halo mass, on average, the H i mass increases with the sum of the neutrino masses. Our results show that H i is more strongly clustered in cosmologies with massive neutrinos, while its abundance, ΩH i(z), is lower. These effects arise mainly from the impact of massive neutrinos on cosmology: they suppress both the amplitude of the matter power spectrum on small scales and the abundance of dark matter halos. Modeling the H i distribution with hydrodynamic simulations at z > 3 and a simple analytic model at z < 3, we use the Fisher matrix formalism to conservatively forecast the constraints that Phase 1 of the Square Kilometre Array will place on the sum of neutrino masses, Mν ≡ Σ mν. We find that with 10,000 hr of interferometric observations at 3 ≲ z ≲ 6 from a deep and narrow survey with SKA1-LOW, the sum of the neutrino masses can be measured with an error σ(Mν) ≲ 0.3 eV (95% CL). Similar constraints can be obtained with a wide and deep SKA1-MID survey at z ≲ 3, using the single-dish mode. By combining data from MID, LOW, and Planck, plus priors on cosmological parameters from a Stage IV spectroscopic galaxy survey, the sum of the neutrino masses can be determined with an error σ(Mν) ≃ 0.06 eV (95% CL).

  13. Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999–2004

    PubMed Central

    Dinse, Gregg E.; Jusko, Todd A.; Whitt, Irene Z.; Co, Caroll A.; Parks, Christine G.; Satoh, Minoru; Chan, Edward K.L.; Rose, Kathryn M.; Walker, Nigel J.; Birnbaum, Linda S.; Zeldin, Darryl C.; Weinberg, Clarice R.; Miller, Frederick W.

    2015-01-01

    Background: Potential associations between background environmental chemical exposures and autoimmunity are understudied. Objectives: Our exploratory study investigated exposure to individual environmental chemicals and selected mixtures in relation to the presence of antinuclear antibodies (ANA), a widely used biomarker of autoimmunity, in a representative sample of the U.S. population. Methods: This cross-sectional analysis used data on 4,340 participants from the National Health and Nutrition Examination Survey (1999–2004), of whom 14% were ANA positive, to explore associations between ANA and concentrations of dioxins, dibenzofurans, polychlorinated biphenyls, organochlorines, organophosphates, phenols, metals, and other environmental exposures and metabolites measured in participants’ serum, whole blood, or urine. For dioxin-like compounds with toxic equivalency factors, we developed and applied a new statistical approach to study selected mixtures. Lognormal models and censored-data methods produced estimates of chemical associations with ANA in males, nulliparous females, and parous females; these estimates were adjusted for confounders and accommodated concentrations below detectable levels. Results: Several associations between chemical concentration and ANA positivity were observed, but only the association in males exposed to triclosan remained statistically significant after correcting for multiple comparisons (mean concentration ratio = 2.8; 95% CI: 1.8, 4.5; p < 0.00001). Conclusions: These data suggest that background levels of most xenobiotic exposures typical in the U.S. population are not strongly associated with ANA. Future studies should ideally reduce exposure misclassification by including prospective measurement of the chemicals of concern and should track changes in ANA and other autoantibodies over time. Citation: Dinse GE, Jusko TA, Whitt IZ, Co CA, Parks CG, Satoh M, Chan EKL, Rose KM, Walker NJ, Birnbaum LS, Zeldin DC, Weinberg CR

  14. DES J0454–4448: Discovery of the first luminous z ≥ 6 quasar from the Dark Energy Survey

    DOE PAGES

    Reed, S. L.

    2015-10-28

    We present the first results of a survey for high-redshift, z ≥ 6, quasars using izY multicolour photometric observations from the Dark Energy Survey (DES). Here we report the discovery and spectroscopic confirmation of the zAB, YAB = 20.2, 20.2 (M1450 = –26.5) quasar DES J0454–4448 with a redshift of z = 6.09±0.02 based on the onset of the Ly α forest and an H i near zone size of 4.1+1.1–1.2 proper Mpc. The quasar was selected as an i-band drop out with i–z = 2.46 and zAB < 21.5 from an area of ~300 deg2. It is the brightestmore » of our 43 candidates and was identified for spectroscopic follow-up solely based on the DES i–z and z–Y colours. The quasar is detected by WISE and has W1AB = 19.68. The discovery of one spectroscopically confirmed quasar with 5.7 < z < 6.5 and zAB ≤ 20.2 is consistent with recent determinations of the luminosity function at z ~ 6. DES when completed will have imaged ~5000 deg2 to YAB = 23.0 (5σ point source) and we expect to discover 50–100 new quasars with z > 6 including 3–10 with z > 7 dramatically increasing the numbers of quasars currently known that are suitable for detailed studies.« less

  15. The morphological changes of mucous membrane of stomach and duodenum of contractor organization personnel, which works in radiation hazard conditions at the object Shelter of Chornobyl NPP.

    PubMed

    Sushko, V O; Nezgovorova, G A; Degtjarova, L V; Kolosynska, O O; Gromadska, V M

    2015-12-01

    Meta doslidzhennia: vyznachennia morfologichnykh osoblyvostei urazhen' slyzovoi obolonky (SO) shlunka ta dvanadtsiatypaloi kyshky (DPK) u personalu, iakyi pratsiuie v radiatsiino nebezpechnykh umovakh na ob’iekti «Ukryttia» Chornobyl's'koi AES (OU) shliakhom endoskopichnogo monitoryngu iz vziattiam biopsiinogo materialu z gastroduodenal'noi zony na etapakh pervynnogo (vkhidnogo) VkhK ta spetsial'nogo medychnogo kontroliu (SpK).Materialy ta metody: provedeno kompleksne klinichne-endoskopichne ta morfologichnogo doslidzhennia z biopsiieiu SO shlunka ta DPK u 126 robitnykiv OU.Rezul'taty: U personalu pidriadnykh pidpryiemstv OU vstanovleni riznoskerovani patomorfologichni zmin SO pry VkhK ta zbil'shennia chastoty ikh vyiavlennia pry obstezhenni pid chas SpK, shcho zagalom vidpovidaly khronichnomu H.pylori-asotsiiovanogo pangastrytu z porushenniam mikrotsyrkuliatsii i trofiky, dysregeneratsiinymy zminamy epitelial'noi vystilky.Vysnovky: dlia personalu pidriadnykh organizatsii, iakyi pryimaie uchast' v radiatsiino-nebezpechnykh robotakh na OU ie kharakternym naiavnist' khronichnogo H.pylori-asotsiiovanogo pangastrytu z zrostanniam chastoty atrofichnykh zmin SO (nemetaplastychnogo chy metaplastychnogo typu) ta rozvytkom erozyvno-vyrazkovykh urazhen' gastroduodenal'noi zony.V robitnykiv, iaki maly poperednii vplyv ionizuiuchogo oprominennia vstanovleno bil'shu chastotu dysregeneratsiinykh (giperplazii / kyshkovoi metaplazii) zmin epiteliiu, shcho vidpovidno pidvyshchuie ryzyk neoplastychnykh transformatsii.Provedennia EGDFS (za neobkhidnosti z biopsiieiu SO) pry VkhK ta nastupnykh etapakh medychnogo kontroliu u personalu, iakyi vykonuie radiatsiino-nebezpechni roboty na OU ie vysokoinformatyvnym dokazovym i neobkhidnym metodom doslidzhennia dlia vyznachennia formy ta stupeniu patologichnykh zmin verkhnikh viddiliv shlunkovo-kyshkovogo traktu dlia poperedzhennia progresuvannia zakhvoriuvannia ta rozvytku uskladnen', zberezhennia zdorov’ia i pratsezdatnosti robitnykiv.

  16. Defining the Flora Family: Reflectance Properties and Age

    NASA Astrophysics Data System (ADS)

    Dykhuis, Melissa J.; Molnar, Lawrence A.; Van Kooten, Samuel J; Greenberg, Richard

    2014-05-01

    The Flora family resides in the densely populated inner main belt, bounded in semimajor axis by the ν6 secular resonance and the Jupiter 3:1 mean motion resonance. The presence of several large families that overlap dynamically with the Floras (e.g. the Vesta, Baptistina, and Nysa-Polana families), and the removal of a significant fraction of Floras via the nearby ν6 resonance have historically complicated the Flora family's distinction in both proper orbital elements and reflectance properties. Here we use orbital information from AstDyS, color information from SDSS, and albedo information from WISE, to obtain the characteristic orbital and reflectance properties of the Floras, by sampling the core of the family in multidimensional phase space. We find the characteristic Flora SDSS colors to be a* = 0.127 ± 0.012 and i-z = -0.038 ± 0.008; the characteristic Flora albedo is pV = 0.295 ± 0.006. These properties allow us to select a high-purity sample of Floras with similar orbital and reflectance properties as required for a detailed dynamical study. We then use the young Karin family, for which we have an age determined via direct backward integration of members' orbits, to calibrate the Yarkovsky drift rates for the Flora family without having to estimate the Floras' material properties. The size-dependent dispersion of the Flora members in semimajor axis (the "V" plot) then yields an age for the family of 940+160-120 My. We discuss the effects on our age estimate of two independent processes that both introduce obliquity variations among the family members on short (My) timescales: 1) the capture of Flora members in spin-orbit resonance, and 2) YORP-driven obliquity variation through YORP cycles. Accounting for these effects does not significantly change the age determination.

  17. VizieR Online Data Catalog: SLoWPoKES-II catalog (Dhital+, 2015)

    NASA Astrophysics Data System (ADS)

    Dhital, S.; West, A. A.; Stassun, K. G.; Schluns, K. J.; Massey, A. P.

    2015-11-01

    We have identified the Sloan Low-mass Wide Pairs of Kinematically Equivalent Systems (SLoWPoKES)-II catalog of 105537 wide, low-mass binaries without using proper motions. We extend the SLoWPoKES catalog (Paper I; Dhital et al. 2010, cat. J/AJ/139/2566) by identifying binary systems with angular separations of 1-20'' based entirely on SDSS photometry and astrometry. As in Paper I, we used the Catalog Archive Server query tool (CasJobs6; http://skyserver.sdss3.org/CasJobs/) to select the sample of low-mass stars from the SDSS-DR8 star table as having r-i>=0.3 and i-z>=0.2, consistent with spectral types of K5 or later. Following Paper I (Dhital et al. 2010, cat. J/AJ/139/2566) we classified candidate pairs with a probability of chance alignment Pf{<=}0.05 as real binaries. We note that this limit does not have any physical motivation but was chosen to minimize the number of spurious pairs. This cut results in 105537 M dwarf (dM)+MS (see Table3), 78 white dwarf (WD)+dM (see Table5), and 184 sdM+sdM (see Table6) binary systems with separations of 1-20''. Of the dM+MS binaries, 44 are very low-mass (VLM) binary candidates (see Table4), with colors redder than the median M7 dwarf for both components. This represents a significant increase over the SLoWPoKES catalog of 1342 common proper motion (CPM) binaries that we presented in Paper I (Dhital et al. 2010, cat. J/AJ/139/2566). The SLoWPoKES and SLoWPoKES-II catalogs are available on the Filtergraph portal (http://slowpokes.vanderbilt.edu/). (4 data files).

  18. Effects of maternal oral administration of morphine sulfate on developing rat fetal cerebrum: a morphometrical evaluation.

    PubMed

    Sadraie, Seyed Homayoon; Kaka, Gholam Reza; Sahraei, Hedayat; Dashtnavard, Hosein; Bahadoran, Hosein; Mofid, Mahmood; Nasab, Hossein Mahdavi; Jafari, Fatemeh

    2008-12-15

    Intrauterine morphine exposure is a risk factor for neurological and behavioral deficit in children, although the precise underlying biological correlate for this is unclear. Female pregnant rats were orally treated with 0.1 mg/ml of morphine solution on the 21st day of gestation. Pregnant rats were killed on the 21st day of gestation and their fetuses were taken out and evaluated for growth and cerebral development. The fetuses were fixed and followed by dehydration through graded ethanol solutions and were then embedded and their heads were coronally sectioned through the frontal cerebral cortex. Quantitative computer-assisted morphometric study was done on the frontal cerebral cortex (FCC) which consists of cortical plate (CP), intermediate (migratory) zone (IZ) and matrix (proliferative) zone (MZ) in the rat embryos. The results showed that morphine exposure caused a significant reduction of fetal weight and crown-to-rump length in morphine exposure group. The present study showed that animals with intrauterine morphine exposure, induced by a period of reduced placental blood flow during the second week of pregnancy, demonstrate reduced both cortical thickness and the numbers of neurons in the developing fetal frontal cerebral cortex (FCC). Histomorphometric evaluation revealed that the thickness of the CP was significantly decreased in the morphine-exposed embryos. In addition, neuronal counting showed that cell proliferation in the CP was suppressed after morphine administration and that the migration of neurons from the matrix zone (MZ) to the cortex was decelerated. In conclusion, these results showed that morphine exposure during the second week of pregnancy could affect brain development in a way, which could lead to neurological and behavioral deficits in the postnatal animal.

  19. DES J0454–4448: Discovery of the first luminous z ≥ 6 quasar from the Dark Energy Survey

    SciTech Connect

    Reed, S. L.

    2015-10-28

    We present the first results of a survey for high-redshift, z ≥ 6, quasars using izY multicolour photometric observations from the Dark Energy Survey (DES). Here we report the discovery and spectroscopic confirmation of the zAB, YAB = 20.2, 20.2 (M1450 = –26.5) quasar DES J0454–4448 with a redshift of z = 6.09±0.02 based on the onset of the Ly α forest and an H i near zone size of 4.1+1.1–1.2 proper Mpc. The quasar was selected as an i-band drop out with i–z = 2.46 and zAB < 21.5 from an area of ~300 deg2. It is the brightest of our 43 candidates and was identified for spectroscopic follow-up solely based on the DES i–z and z–Y colours. The quasar is detected by WISE and has W1AB = 19.68. The discovery of one spectroscopically confirmed quasar with 5.7 < z < 6.5 and zAB ≤ 20.2 is consistent with recent determinations of the luminosity function at z ~ 6. DES when completed will have imaged ~5000 deg2 to YAB = 23.0 (5σ point source) and we expect to discover 50–100 new quasars with z > 6 including 3–10 with z > 7 dramatically increasing the numbers of quasars currently known that are suitable for detailed studies.

  20. Some principles for formation of self-developing dichromate media

    NASA Astrophysics Data System (ADS)

    Sherstyuk, Valentin P.; Malov, Alexander N.; Maloletov, Sergei M.; Kalinkin, Vyacheslav V.

    1991-02-01

    The optical information recorded in dichromate gelatin (DCG) layers Induced the information of a latent. image Which rnder the action of water and alcohols transforms to a relief or Phase image. The action of water vapours ma appreciably increase diffraction efficiency. judging from the assumPtion that the introduction of multiatomic alcohols favours the retention of water'' moecu1es in a lager in the amount sufficient for deve1oment on its exposure and stabilization of chromium complexes1 a " self-development" regim has teen worked out. In this case the diffraction efficiency of recorded hc. 1ograms is c''ose to the theoretical limiting value for flatphase r''e c o rdI ng me (J i a. At present the occurence of a Primary latent holographic image (or structure) in dichromated gelatin (DCG) layers has been recognized The diffraction efficiency (DE) detected at a step of holographic recording is low (about 0. 1-IZ). It was shown earlier /j_ 2/ that the treatment bY water vaours or eXPOSUPC Of the layers under conditions of increased humidity results ma growth of DE up to the values enabling the use of DCG to record information in real time /3/j Latent image centres in exposed DC3 layers are predominantly chromium(V) compounds. It is particulary evidenced by the observed correlation between the rate of formation of Cr(V) compounds in a Photo process and the specific change in DE of a latent image /5/.

  1. WEIGHING NEUTRINOS WITH COSMIC NEUTRAL HYDROGEN

    SciTech Connect

    Villaescusa-Navarro, Francisco; Viel, Matteo; Bull, Philip E-mail: viel@oats.inaf.it

    2015-12-01

    We investigate the signatures left by massive neutrinos on the spatial distribution of neutral hydrogen (H i) in the post-reionization era by running hydrodynamic simulations that include massive neutrinos as additional collisionless particles. We find that halos in massive/massless neutrino cosmologies host a similar amount of neutral hydrogen, although for a fixed halo mass, on average, the H i mass increases with the sum of the neutrino masses. Our results show that H i is more strongly clustered in cosmologies with massive neutrinos, while its abundance, Ω{sub H} {sub i}(z), is lower. These effects arise mainly from the impact of massive neutrinos on cosmology: they suppress both the amplitude of the matter power spectrum on small scales and the abundance of dark matter halos. Modeling the H i distribution with hydrodynamic simulations at z > 3 and a simple analytic model at z < 3, we use the Fisher matrix formalism to conservatively forecast the constraints that Phase 1 of the Square Kilometre Array will place on the sum of neutrino masses, M{sub ν} ≡ Σ m{sub ν}. We find that with 10,000 hr of interferometric observations at 3 ≲ z ≲ 6 from a deep and narrow survey with SKA1-LOW, the sum of the neutrino masses can be measured with an error σ(M{sub ν}) ≲ 0.3 eV (95% CL). Similar constraints can be obtained with a wide and deep SKA1-MID survey at z ≲ 3, using the single-dish mode. By combining data from MID, LOW, and Planck, plus priors on cosmological parameters from a Stage IV spectroscopic galaxy survey, the sum of the neutrino masses can be determined with an error σ(M{sub ν}) ≃ 0.06 eV (95% CL)

  2. Open air mineral treatment operations and ambient air quality: assessment and source apportionment.

    PubMed

    Escudero, M; Alastuey, A; Moreno, T; Querol, X; Pérez, P

    2012-11-01

    We present a methodology for evaluating and quantifying the impact of inhalable mineral dust resuspension close to a potentially important industrial point source, in this case an open air plant producing sand, flux and kaolin in the Capuchinos district of Alcañiz (Teruel, NE Spain). PM(10) levels at Capuchinos were initially high (42 μg m(-3) as the annual average with 91 exceedances of the EU daily limit value during 2007) but subsequently decreased (26 μg m(-3) with 16 exceedances in 2010) due to a reduced demand for minerals from the ceramic industry and construction sector during the first stages of the economic crisis. Back trajectory and local wind pattern analyses revealed only limited contribution from exotic PM sources such as African dust intrusions whereas there was clearly a strong link with the mineral stockpiles of the local industry. This link was reinforced by chemical and mineral speciation and source apportionment analysis which showed a dominance of mineral matter (sum of CO(3)(2-), SiO(2), Al(2)O(3), Ca, Fe, K, Mg, P, and Ti: mostly aluminosilicates) which in 2007 contributed 76% of the PM(10) mass (44 μg m(-3) on average). The contribution from Secondary Inorganic Aerosols (SIA, sum of SO(4)(2-), NO(3)(-) and NH(4)(+)) reached 8.4 μg m(-3), accounting for 14% of the PM(10) mass, similar to the amount of calcareous road dust estimated to be present (8 μg m(-3); 13%). Organic matter and elemental carbon contributed 5.3 μg m(-3) (9%) whereas marine aerosol (Na + Cl) levels were minor with an average concentration of 0.4 μg m(-3) (1% of the PM(10) mass). Finally, chemical and mineralogical analysis of stockpile samples and comparison with filter samples confirmed the local industry to be the major source of ambient PM(10) in the area.

  3. The risk of macular degeneration development in persons antenatally irradiated as a result of Chornobyl NPP accident.

    PubMed

    Babenko, T F; Fedirko, P A; Dorichevska, R Y; Denysenko, N V; Samoteikina, L A; Tyshchenko, O P

    2016-12-01

    Meta. Otsinyty ryzyk rozvytku makuliarnoï degeneratsiï u osib, oprominenykh vnutrishn'outrobno vnaslidok avariï na Chornobyl's'kiy̆ AES.Materialy i metody. Ob’iektom doslidzhennia buv stan makuliarnoï zony sitkivky 84 osib, oprominenykh vnutrishn' outrobno vnaslidok Chornobyl's'koï katastrofy, obstezhenykh u vitsi 14–30 rokiv. Vykorystano rezul'taty stan dartyzovanykh oftal'mologichnykh obstezhen', provedenykh z 2000 po 2016 rr. Kontrol'nu grupu sklaly 165 osib, iaki ne zaznaly vnutrishn'outrobnogo oprominennia i buly obstezheni v tomu zh vitsi, shcho y̆ osoby osnovnoï grupy. Vsi patsiienty buly obstezheni zgidno z formalizovanym oftal'mologichnym protokolom, protsedura obstezhennia vkliuchala oftal'moskopiiu i fotografuvannia na fundus kameri (ustanovka VISUKAM lite Digital Camera, Zeiss). Provodylas' statystychna obrobka rezul'tativ iz vykorystanniam probnoï vil'noï versiï paketu program «Open Epi 2.2.1».Rezul'taty. Pokazano, shcho poshyrenist' makuliarnoï degeneratsiï sitkivky u vitsi 14–30 rokiv dlia oprominenykh in utero osib stanovyla 95,23 ± 32,03 na 1000 i v porivnianni z vikovym kontrolem (17,86 ± 10,31 na 1000) bula dos tovirno vyshchoiu (χ2 = 7,827, r = 0,0026).Vysnovky. U vikoviy̆ grupi do 30 rokiv u oprominenykh antenatal'no osib z’iavliaiut'sia makuliarni degeneratsiï, iaki za klinichnoiu kartynoiu nagaduiut' vikovu makuliarnu degeneratsiiu. Dovedeno, shcho poshyrenist' makuliarnoï dege neratsiï dostovirno vyshcha v grupi osib, oprominenykh antenatal'no, v porivnianni z neoprominenym kontrolem togo zh viku.

  4. Safety Culture Assessment in Petrochemical Industry: A Comparative Study of Two Algerian Plants

    PubMed Central

    Boughaba, Assia; Hassane, Chabane; Roukia, Ouddai

    2014-01-01

    Background To elucidate the relationship between safety culture maturity and safety performance of a particular company. Methods To identify the factors that contribute to a safety culture, a survey questionnaire was created based mainly on the studies of Fernández-Muñiz et al. The survey was randomly distributed to 1000 employees of two oil companies and realized a rate of valid answer of 51%. Minitab 16 software was used and diverse tests, including the descriptive statistical analysis, factor analysis, reliability analysis, mean analysis, and correlation, were used for the analysis of data. Ten factors were extracted using the analysis of factor to represent safety culture and safety performance. Results The results of this study showed that the managers' commitment, training, incentives, communication, and employee involvement are the priority domains on which it is necessary to stress the effort of improvement, where they had all the descriptive average values lower than 3.0 at the level of Company B. Furthermore, the results also showed that the safety culture influences the safety performance of the company. Therefore, Company A with a good safety culture (the descriptive average values more than 4.0), is more successful than Company B in terms of accident rates. Conclusion The comparison between the two petrochemical plants of the group Sonatrach confirms these results in which Company A, the managers of which are English and Norwegian, distinguishes itself by the maturity of their safety culture has significantly higher evaluations than the company B, who is constituted of Algerian staff, in terms of safety management practices and safety performance. PMID:25180135

  5. RefMoB, a Reflectivity Feature Model-Based Automated Method for Measuring Four Outer Retinal Hyperreflective Bands in Optical Coherence Tomography

    PubMed Central

    Ross, Douglas H.; Clark, Mark E.; Godara, Pooja; Huisingh, Carrie; McGwin, Gerald; Owsley, Cynthia; Litts, Katie M.; Spaide, Richard F.; Sloan, Kenneth R.; Curcio, Christine A.

    2015-01-01

    Purpose. To validate a model-driven method (RefMoB) of automatically describing the four outer retinal hyperreflective bands revealed by spectral-domain optical coherence tomography (SDOCT), for comparison with histology of normal macula; to report thickness and position of bands, particularly band 2 (ellipsoid zone [EZ], commonly called IS/OS). Methods. Foveal and superior perifoveal scans of seven SDOCT volumes of five individuals aged 28 to 69 years with healthy maculas were used (seven eyes for validation, five eyes for measurement). RefMoB determines band thickness and position by a multistage procedure that models reflectivities as a summation of Gaussians. Band thickness and positions were compared with those obtained by manual evaluators for the same scans, and compared with an independent published histological dataset. Results. Agreement among manual evaluators was moderate. Relative to manual evaluation, RefMoB reported reduced thickness and vertical shifts in band positions in a band-specific manner for both simulated and empirical data. In foveal and perifoveal scans, band 1 was thick relative to the anatomical external limiting membrane, band 2 aligned with the outer one-third of the anatomical IS ellipsoid, and band 3 (IZ, interdigitation of retinal pigment epithelium and photoreceptors) was cleanly delineated. Conclusions. RefMoB is suitable for automatic description of the location and thickness of the four outer retinal hyperreflective bands. Initial results suggest that band 2 aligns with the outer ellipsoid, thus supporting its recent designation as EZ. Automated and objective delineation of band 3 will help investigations of structural biomarkers of dark-adaptation changes in aging. PMID:26132776

  6. Semi-blind Eigen Analyses of Recombination Histories Using Cosmic Microwave Background Data

    NASA Astrophysics Data System (ADS)

    Farhang, M.; Bond, J. R.; Chluba, J.

    2012-06-01

    Cosmological parameter measurements from cosmic microwave background (CMB) experiments, such as Planck, ACTPol, SPTPol, and other high-resolution follow-ons, fundamentally rely on the accuracy of the assumed recombination model or one with well-prescribed uncertainties. Deviations from the standard recombination history might suggest new particle physics or modified atomic physics. Here we treat possible perturbative fluctuations in the free electron fraction, X e(z), by a semi-blind expansion in densely packed modes in redshift. From these we construct parameter eigenmodes, which we rank order so that the lowest modes provide the most power to probe X e(z) with CMB measurements. Since the eigenmodes are effectively weighed by the fiducial X e history, they are localized around the differential visibility peak, allowing for an excellent probe of hydrogen recombination but a weaker probe of the higher redshift helium recombination and the lower redshift highly neutral freezeout tail. We use an information-based criterion to truncate the mode hierarchy and show that with even a few modes the method goes a long way from the fiducial recombination model computed with RECFAST, X e, i(z), toward the precise underlying history given by the new and improved recombination calculations of COSMOREC or HYREC, X e, f(z), in the hydrogen recombination regime, though not well in the helium regime. Without such a correction, the derived cosmic parameters are biased. We discuss an iterative approach for updating the eigenmodes to further hone in on X e, f(z) if large deviations are indeed found. We also introduce control parameters that downweight the attention on the visibility peak structure, e.g., focusing the eigenmode probes more strongly on the X e(z) freezeout tail, as would be appropriate when looking for the X e signature of annihilating or decaying elementary particles.

  7. A new free-floating planet in the Upper Scorpius association

    NASA Astrophysics Data System (ADS)

    Peña Ramírez, K.; Béjar, V. J. S.; Zapatero Osorio, M. R.

    2016-02-01

    We report on a deep photometric survey covering an area of 1.17 deg2 in the young Upper Scorpius stellar association using VIMOS Iz and UKIDSS ZJHK data that was taken with several years in between. The search for the least massive population of Upper Scorpius (~5-10 Myr, 145 pc) is performed on the basis of various optical and infrared color-color and color-magnitude diagrams, including WISE photometry, in the magnitude interval J = 14.5-19 mag (completeness), which corresponds to substellar masses from 0.028 through 0.004 M⊙ at the age and distance of Upper Scorpius. We also present the proper motion analysis of the photometric candidates, finding that two objects successfully pass all photometric and astrometric criteria for membership in the young stellar association. One of them, USco J155150.2-213457, is a new discovery. We obtained low resolution, near-infrared spectroscopy (R ~ 450, 0.85-2.35 μm) of this new finding using the FIRE instrument. We confirmed its low-gravity atmosphere expected for an Upper Scorpius member (weak alkaline lines, strong VO absorption, peaked H-band pseudocontinuum). By comparison with spectroscopic standards, we derive a spectral type of L6 ± 1, and estimate a mass of ≈0.008-0.010 M⊙ for USco J155150.2-213457. The colors and spectral slope of this object resemble those of other young, cool members of Upper Scorpius and σ Orionis (~3 Myr) and field, high gravity dwarfs of related classification in contrast with the very red indices of field, low gravity, L-type dwarfs of intermediate age. USco J155150.2-213457, which does not show infrared flux excesses up to 4.5 μm, becomes one of the least massive and latest type objects known in the entire Upper Scorpius stellar association.

  8. CLASH: COMPLETE LENSING ANALYSIS OF THE LARGEST COSMIC LENS MACS J0717.5+3745 AND SURROUNDING STRUCTURES

    SciTech Connect

    Medezinski, Elinor; Lemze, Doron; Ford, Holland; Umetsu, Keiichi; Nonino, Mario; Zitrin, Adi; Broadhurst, Tom; Sayers, Jack; Czakon, Nicole; Waizmann, Jean-Claude; Meneghetti, Massimo; Koekemoer, Anton; Coe, Dan; Postman, Marc; Molino, Alberto; Melchior, Peter; Grillo, Claudio; and others

    2013-11-01

    The galaxy cluster MACS J0717.5+3745 (z = 0.55) is the largest known cosmic lens, with complex internal structures seen in deep X-ray, Sunyaev-Zel'dovich effect, and dynamical observations. We perform a combined weak- and strong-lensing analysis with wide-field BVR{sub c} i'z' Subaru/Suprime-Cam observations and 16-band Hubble Space Telescope observations taken as part of the Cluster Lensing And Supernova survey with Hubble. We find consistent weak distortion and magnification measurements of background galaxies and combine these signals to construct an optimally estimated radial mass profile of the cluster and its surrounding large-scale structure out to 5 Mpc h {sup –1}. We find consistency between strong-lensing and weak-lensing in the region where these independent data overlap, <500 kpc h {sup –1}. The two-dimensional weak-lensing map reveals a clear filamentary structure traced by distinct mass halos. We model the lensing shear field with nine halos, including the main cluster, corresponding to mass peaks detected above 2.5σ{sub κ}. The total mass of the cluster as determined by the different methods is M{sub vir} ≈ (2.8 ± 0.4) × 10{sup 15} M{sub ☉}. Although this is the most massive cluster known at z > 0.5, in terms of extreme value statistics, we conclude that the mass of MACS J0717.5+3745 by itself is not in serious tension with ΛCDM, representing only a ∼2σ departure above the maximum simulated halo mass at this redshift.

  9. TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells.

    PubMed

    Tuthill, M H; Montinaro, A; Zinngrebe, J; Prieske, K; Draber, P; Prieske, S; Newsom-Davis, T; von Karstedt, S; Graves, J; Walczak, H

    2015-04-16

    Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in cancer cells while sparing normal tissues. Despite promising preclinical results, few patients responded to treatment with recombinant TRAIL (Apo2L/Dulanermin) or TRAIL-R2-specific antibodies, such as conatumumab (AMG655). It is unknown whether this was due to intrinsic TRAIL resistance within primary human cancers or insufficient agonistic activity of the TRAIL-receptor (TRAIL-R)-targeting drugs. Fcγ receptors (FcγR)-mediated crosslinking increases the cancer-cell-killing activity of TRAIL-R2-specific antibodies in vivo. We tested this phenomenon using FcγR-expressing immune cells from patients with ovarian cancer. However, even in the presence of high numbers of FcγR-expressing immune cells, as found in ovarian cancer ascites, AMG655-induced apoptosis was not enabled to any significant degree, indicating that this concept may not translate into clinical use. On the basis of these results, we next set out to determine whether AMG655 possibly interferes with apoptosis induction by endogenous TRAIL, which could be expressed by immune cells. To do so, we tested how AMG655 affected apoptosis induction by recombinant TRAIL. This, however, resulted in the surprising discovery of a striking synergy between AMG655 and non-tagged TRAIL (Apo2L/TRAIL) in killing cancer cells. This combination was as effective in killing cancer cells as highly active recombinant isoleucine-zipper-tagged TRAIL (iz-TRAIL). The increased killing efficiency was due to enhanced formation of the TRAIL death-inducing signalling complex, enabled by concomitant binding of Apo2L/TRAIL and AMG655 to TRAIL-R2. The synergy of AMG655 with Apo2L/TRAIL extended to primary ovarian cancer cells and was further enhanced by combination with the proteasome inhibitor bortezomib or a second mitochondrial-derived activator of caspases (SMAC) mimetic. Importantly, primary human hepatocytes were not killed by the AMG655-Apo2L

  10. Multicolor surface photometry of a sample of low luminosity radio galaxies

    NASA Astrophysics Data System (ADS)

    Sahu, Sheetal Kumar; Pandey, S. K.; Chakradhari, N. K.; Baburao Pandge, Mahadev

    2015-08-01

    We present a detailed multiband photometric study of five galaxies, selected from a sample of low luminosity early-type galaxies from B2 sample, which have mpg = 15.7, mV = 16.5, redshifts up to 0.2, radio powers P408 = 1023 - 1026.5 W Hz-1 and between 1022 - 1025 W Hz-1 at 1.4 GHz. We have used observed BVR and Hα images from IGO 2m telescope (Pune, India) and 2m HCT, Indian Astronomical Observatory (IAO Hanle, India), and archival multiband data from SDSS (ugriz), 2MASS (JHKs ), WISE, Spitzer (mid-IR), XMM, CHANDRA (X-ray), UV (GALEX) and radio from VLA, IRAM for this study.We used standard technique of surface photometry by fitting ellipses to the isophotes for studying the distribution of light in the galaxies by studying their surface brightness profiles, ellipticity profiles, position angle profiles, variation of center of isophotes along semi-major axis, shapes of isophotes, radial color gradients, twists in isophotes and fine structure variations from smooth light profile. The obtained surface brightness profiles are fitted to the core-Sersic model for decomposing the galaxy light profiles and quantify the radial stellar distributions of the sample galaxies.The multiband color index profiles, e.g. u-g, g-r, r-i, i-z, B-R, B-V, J-Hs , J-Ks , H-Ks , R-Ks , 3.4-4.6 μm, 4.6-12 μm (mid-IR) and FUV-NUV(UV), are obtained and combined with various maps e.g . unsharp-masked images, residual maps, quotient maps, dust extinction maps, Hα emission maps, CO intensity maps, diffuse X-ray emission maps and extinction curves of the galaxies to study the morphology, properties and physical correlations of different phases (e.g cool gas, dust, ionized gas and hot gases) of Inter Stellar Medium and to examine various star formation related processes in the galaxies.

  11. Level repulsion exponent β for many-body localization transitions and for Anderson localization transitions via Dyson Brownian motion

    NASA Astrophysics Data System (ADS)

    Monthus, Cécile

    2016-03-01

    The generalization of the Dyson Brownian motion approach of random matrices to Anderson localization (AL) models (Chalker et al 1996 Phys. Rev. Lett. 77 554) and to many-body localization (MBL) Hamiltonians (Serbyn and Moore 2015 arXiv:1508.07293) is revisited to extract the level repulsion exponent β, where β =1 in the delocalized phase governed by the Wigner-Dyson statistics, β =0 , in the localized phase governed by the Poisson statistics, and 0<{βc}<1 at the critical point. The idea is that the Gaussian disorder variables h i are promoted to Gaussian stationary processes h i (t) in order to sample the disorder stationary distribution with some time correlation τ. The statistics of energy levels can then be studied via Langevin and Fokker-Planck equations. For the MBL quantum spin Hamiltonian with random fields h i , we obtain β =2qn,n+1\\text{EA}(N)/qn,n\\text{EA}(N) in terms of the Edwards-Anderson matrix qnm\\text{EA}(N)\\equiv \\frac{1}{N}{\\sum}i=1N|< {φn}|σ iz|{φm}> {{|}2} for the same eigenstate m  =  n and for consecutive eigenstates m  =  n  +  1. For the Anderson localization tight-binding Hamiltonian with random on-site energies h i , we find β =2{{Y}n,n+1}(N)/≤ft({{Y}n,n}(N)-{{Y}n,n+1}(N)\\right) in terms of the density correlation matrix {{Y}nm}(N)\\equiv {\\sum}i=1N|< {φn}|i> {{|}2}|< i|{φm}> {{|}2} for consecutive eigenstates m  =  n  +  1, while the diagonal element m  =  n corresponds to the inverse participation ratio {{Y}nn}(N)\\equiv {\\sum}i=1N|< {φn}|i> {{|}4} of the eigenstate |{φn}> .

  12. Lead(II)-catalyzed oxidation of guanine in solution studied with electrospray ionization mass spectrometry.

    PubMed

    Banu, Laura; Blagojevic, Voislav; Bohme, Diethard K

    2012-10-04

    The oxidation of guanine was investigated in water/methanol solution both in the absence and in the presence of Pb(II) with a variable temperature reactor coupled to a tandem mass spectrometer that allowed signature ions of solution reagents and products to be monitored by electrospray ionization (ESI). Two different oxidizing agents were employed, one strong (peroxymonosulfuric acid) and one weaker (hydrogen peroxide). Peroxymonosulfuric acid was observed to oxidize guanine rapidly at room temperature, k(app) > 10(-2) s(-1), whether in the absence or in the presence of Pb(II), to produce spiroiminohydantoin. Guanine did not show measurable oxidation by hydrogen peroxide in the absence of Pb(II) at concentrations of H(2)O(2) up to 1 M at temperatures up to 333 K (k(app) < 3 × 10(-8) s(-1) at 298 K), but in the presence of Pb(II), it was observed to produce both 5-carboxamido-5-formamido-2-iminohydantoin (2-Ih) and imidazolone (Iz) in a ratio of 2.3 ± 0.1 with a total rate enhancement of more than 4 × 10(3). The activation energy was measured to be 82 ± 11 kJ mol(-1) and is more than 120 kJ mol(-1) lower than that for the uncatalyzed oxidation with hydrogen peroxide measured to be at least 208 ± 26 kJ mol(-1). An activation energy of 113 ± 9 kJ mol(-1) has been reported by Bruskov et al. (Nucleic Acids Res.2002, 30, 1354) for the heat-induced oxidation by hydrogen peroxide of guanine embedded as guanosine in DNA which leads to the production of 8-oxo-7,8-dihydro-guanine (8-oxo-Gua). The atomic lead dication lowers the activation energy by activating the hydrogen peroxide oxidant, possibly by O-O bond activation, and by directing the oxidation, possibly through coordination to the functional groups adjacent to the carbon C5: the C6 carbonyl group and the N7 nitrogen. The coupling of tandem mass spectrometry (MS(2)) with a simple variable temperature reactor by ESI proved to be very effective for measuring reaction kinetics and activation energies in solution

  13. Pathways of arachidonic acid peroxyl radical reactions and product formation with guanine radicals.

    PubMed

    Crean, Conor; Geacintov, Nicholas E; Shafirovich, Vladimir

    2008-02-01

    -imidazolone (Iz), dehydroguanidinohydantoin (Gh ox), and diastereomeric spiroiminodihydantoin (Sp) nucleosides from 2',3',5'-tri- O-acetylguanosine and the Gh ox and Sp nucleosides from 2',3',5'-tri- O-acetyl-8-oxo-7,8-dihydroguanosine. In air-saturated aqueous solutions, covalent alkylated guanine adducts were not detected.

  14. Foot-and-Mouth Disease in Red Deer - Experimental Infection and Test Methods Performance.

    PubMed

    Kittelberger, R; Nfon, C; Swekla, K; Zhang, Z; Hole, K; Bittner, H; Salo, T; Goolia, M; Embury-Hyatt, C; Bueno, R; Hannah, M; Swainsbury, R; O'Sullivan, C; Spence, R; Clough, R; McFadden, A; Rawdon, T; Alexandersen, S

    2017-02-01

    The aim of this study was to evaluate a number of foot-and-mouth disease (FMD) test methods for use in red deer. Ten animals were intranasally inoculated with the FMD virus (FMDV) O UKG 11/2001, monitored for clinical signs, and samples taken regularly (blood, serum, oral swabs, nasal swabs, probang samples and lesion swabs, if present) over a 4-week period. Only one animal, deer 1103, developed clinical signs (lesions under the tongue and at the coronary band of the right hind hoof). It tested positive by 3D and IRES real-time reverse transcription polymerase chain reaction (rRT-PCR) in various swabs, lesion materials and serum. In a non-structural protein (NSP) in-house ELISA (NSP-ELISA-IH), one commercial ELISA (NSP-ELISA-PR) and a commercial antibody NSP pen side test, only deer 1103 showed positive results from day post-inoculation (dpi) 14 onwards. Two other NSP-ELISAs detected anti-NSP serum antibodies with lower sensitivity. It also showed rising antibody levels in the virus neutralization test (VNT), the in-house SPO-ELISA-IH and the commercial SPO-ELISA-PR at dpi 9, and in another two commercial SPO-ELISAs at dpi 12 (SPO-ELISA-IV) and dpi 19 (SPO-ELISA-IZ), respectively. Six of the red deer that had been rRT-PCR and antibody negative were re-inoculated intramuscularly with the same O-serotype FMDV at dpi 14. None of these animals became rRT-PCR or NSP-ELISA positive, but all six animals became positive in the VNT, the in-house SPO-ELISA-IH and the commercial SPO-ELISA-PR. Two other commercial SPO-ELISAs were less sensitive or failed to detect animals as positive. The rRT-PCRs and the four most sensitive commercial ELISAs that had been used for the experimentally inoculated deer were further evaluated for diagnostic specificity (DSP) using 950 serum samples and 200 nasal swabs from non-infected animals. DSPs were 100% for the rRT-PCRs and between 99.8 and 100% for the ELISAs.

  15. The integrated analyses of digital field mapping techniques and traditional field methods: implications from the Burdur-Fethiye Shear Zone, SW Turkey as a case-study

    NASA Astrophysics Data System (ADS)

    Elitez, İrem; Yaltırak, Cenk; Zabcı, Cengiz; Şahin, Murat

    2015-04-01

    The precise geological mapping is one of the most important issues in geological studies. Documenting the spatial distribution of geological bodies and their contacts play a crucial role on interpreting the tectonic evolution of any region. Although the traditional field techniques are still accepted to be the most fundamental tools in construction of geological maps, we suggest that the integration of digital technologies to the classical methods significantly increases the resolution and the quality of such products. We simply follow the following steps in integration of the digital data with the traditional field observations. First, we create the digital elevation model (DEM) of the region of interest by interpolating the digital contours of 1:25000 scale topographic maps to 10 m of ground pixel resolution. The non-commercial Google Earth satellite imagery and geological maps of previous studies are draped over the interpolated DEMs in the second stage. The integration of all spatial data is done by using the market leading GIS software, ESRI ArcGIS. We make the preliminary interpretation of major structures as tectonic lineaments and stratigraphic contacts. These preliminary maps are controlled and precisely coordinated during the field studies by using mobile tablets and/or phablets with GPS receivers. The same devices are also used in measuring and recording the geologic structures of the study region. Finally, all digitally collected measurements and observations are added to the GIS database and we finalise our geological map with all available information. We applied this integrated method to map the Burdur-Fethiye Shear Zone (BFSZ) in the southwest Turkey. The BFSZ is an active sinistral 60-to-90 km-wide shear zone, which prolongs about 300 km-long between Suhut-Cay in the northeast and Köyceğiz Lake-Kalkan in the southwest on land. The numerous studies suggest contradictory models not only about the evolution but also about the fault geometry of this

  16. Studying Big Planets with Small Telescopes: The z'-Band Occultation of WASP-19b Observed with EulerCam and TRAPPIST

    NASA Astrophysics Data System (ADS)

    Lendl, Monika; Gillon, Michael; Queloz, Didier

    2013-04-01

    better than 1% in the r', I+z' and z' bands.

  17. Busca de estruturas em grandes escalas em altos redshifts

    NASA Astrophysics Data System (ADS)

    Boris, N. V.; Sodrã©, L., Jr.; Cypriano, E.

    2003-08-01

    A busca por estruturas em grandes escalas (aglomerados de galáxias, por exemplo) é um ativo tópico de pesquisas hoje em dia, pois a detecção de um único aglomerado em altos redshifts pode por vínculos fortes sobre os modelos cosmológicos. Neste projeto estamos fazendo uma busca de estruturas distantes em campos contendo pares de quasares próximos entre si em z Â3 0.9. Os pares de quasares foram extraídos do catálogo de Véron-Cetty & Véron (2001) e estão sendo observados com os telescópios: 2,2m da University of Hawaii (UH), 2,5m do Observatório de Las Campanas e com o GEMINI. Apresentamos aqui a análise preliminar de um par de quasares observado nos filtros i'(7800 Å) e z'(9500 Å) com o GEMINI. A cor (i'-z') mostrou-se útil para detectar objetos "early-type" em redshifts menores que 1.1. No estudo do par 131046+0006/J131055+0008, com redshift ~ 0.9, o uso deste método possibilitou a detecção de sete objetos candidatos a galáxias "early-type". Num mapa da distribuição projetada dos objetos para 22 < i' < 25 observou-se que estas galáxias estão localizadas próximas a um dos quasares e há indícios de que estejam aglomeradas dentro de um área de ~ 6 arcmin2. Se esse for o caso, estes objetos seriam membros de uma estrutura em grande escala. Um outro argumento em favor dessa hipótese é que eles obedecem uma relação do tipo Kormendy (raio equivalente X brilho superficial dentro desse raio), como a apresentada pelas galáxias elípticas em z = 0.

  18. Ultra-reducing conditions in average mantle peridotites and in podiform chromitites: a thermodynamic model for moissanite (SiC) formation

    NASA Astrophysics Data System (ADS)

    Golubkova, Anastasia; Schmidt, Max W.; Connolly, James A. D.

    2016-05-01

    Natural moissanite (SiC) is reported from mantle-derived samples ranging from lithospheric mantle keel diamonds to serpentinites to podiform chromitites in ophiolites related to suprasubduction zone settings (Luobusa, Dongqiao, Semail, and Ray-Iz). To simulate ultra-reducing conditions and the formation of moissanite, we compiled thermodynamic data for alloys (Fe-Si-C and Fe-Cr), carbides (Fe3C, Fe7C3, SiC), and Fe-silicides; these data were augmented by commonly used thermodynamic data for silicates and oxides. Computed phase diagram sections then constrain the P- T- fO2 conditions of SiC stability in the upper mantle. Our results demonstrate that: Moissanite only occurs at oxygen fugacities 6.5-7.5 log units below the iron-wustite buffer; moissanite and chromite cannot stably coexist; increasing pressure does not lead to the stability of this mineral pair; and silicates that coexist with moissanite have X Mg > 0.99. At upper mantle conditions, chromite reduces to Fe-Cr alloy at fO2 values 3.7-5.3 log units above the moissanite-olivine-(ortho)pyroxene-carbon (graphite or diamond) buffer (MOOC). The occurrence of SiC in chromitites and the absence of domains with almost Fe-free silicates suggest that ultra-reducing conditions allowing for SiC are confined to grain scale microenvironments. In contrast to previous ultra-high-pressure and/or temperature hypotheses for SiC origin, we postulate a low to moderate temperature mechanism, which operates via ultra-reducing fluids. In this model, graphite-/diamond-saturated moderately reducing fluids evolve in chemical isolation from the bulk rock to ultra-reducing methane-dominated fluids by sequestering H2O into hydrous phases (serpentine, brucite, phase A). Carbon isotope compositions of moissanite are consistent with an origin of such fluids from sediments originally rich in organic compounds. Findings of SiC within rocks mostly comprised by hydrous phases (serpentine + brucite) support this model. Both the hydrous phases

  19. Platinum-group elements in alpine-type ultramafic rocks and related chromite ores of the main ophiolite belt of the Urals

    NASA Astrophysics Data System (ADS)

    Volchenko, Yu. A.; Koroteev, V. A.; Neustroeva, I. I.

    2009-04-01

    On the basis of a representative collection of ultramafic rocks and chromite ores and a series of technological samples from the largest (Central and Western) deposits in the Rai-Iz massif of the Polar Urals and the Almaz-Zhemchuzhina and Poiskovy deposits in the Kempirsai massif of the southern Urals, the distribution and speciation of platinum-group elements (PGE) in various type sections of mafic-ultramafic massifs of the Main ophiolite belt of the Urals have been studied. Spectral-chemical and spectrophotometric analyses were carried out to estimate PGE in 700 samples of ultramafic rocks and chromite ores; 400 analyses of minerals from rocks, ores, and concentrates and 100 analyses of PGE minerals (PGM) in chromite ores and concentrates were performed using an electron microprobe. Near-chondritic and nonchondritic PGE patterns in chromitebearing sections have been identified. PGE mineralization has been established to occur in chromite ore from all parts of the mafic-ultramafic massifs in the Main ophiolite belt of the Urals. The PGE deposits and occurrences discovered therein are attributed to four types (Kraka, Kempirsai, Nurali-Upper Neiva, and Shandasha), which are different in mode of geological occurrence, geochemical specialization, and placer-forming capability. Fluid-bearing minerals of the pargasite-edenite series have been identified for the first time in the matrix of chromite ore of the Kempirsai massif (the Almaz-Zhemchuzhina deposit) and Voikar-Syn’ya massif (the Kershor deposit). The PGE grade in various types of chromite ore ranges from 0.1-0.2 to 1-2 g/t or higher. According to technological sampling, the average PGE grade in the largest deposits of the southeastern ore field of the Kempirsai massif is 0.5-0.7 g/t. Due to the occurrence of most PGE as PGM 10-100 mm in size and the proved feasibility of their recovery into nickel alloys, chromites of the Kempirsai massif can be considered a complex ore with elevated and locally high Os, Ir

  20. Evidence for rapid geomagnetic field intensity variations in Western Europe over the past 800 years from new French archeointensity data

    NASA Astrophysics Data System (ADS)

    Genevey, Agnès; Gallet, Yves; Rosen, Jean; Le Goff, Maxime

    2009-06-01

    The number of reliable archeointensity determinations obtained from Western Europe for the past millennium remains limited. Moreover, the large scatter between different datasets available is puzzling. The present study analyzed 31 new groups of baked clay (ceramic or brick) fragments sampled in France (29 groups) and in Belgium (2 groups). These groups contain several fragments collected from different artefacts and are precisely dated principally from historical constraints between the XIIIth and the XIXth centuries. Additionally, we re-evaluated 14 intensity values that we previously obtained from the same time period. The fragments were analyzed using two different thermal methods: (1) the "in field-zero field" (IZ) or the IZZI version of the classical Thellier and Thellier method and (2) the Triaxe protocol that involves high-temperature magnetization measurements. Data were corrected for the anisotropy of thermoremanent magnetization (TRM) and the dependence of TRM acquisition on the cooling rate was taken into account in the different protocols. Archeointensity data obtained on twin specimens sampled from the same fragment and using both experimental techniques generally show a good agreement (i.e. within 5%) at the fragment and at the site level. All retained site-level averaged intensity results (43 of 45 groups) have standard deviations of less than 5 µT. Furthermore, groups of approximately the same age have very consistent archeointensity. Altogether, the data presented herein recover a detailed and smoothed geomagnetic field intensity variation curve characterized by two peaks in intensity, the first during the second half of the XIVth century and the second around AD 1600, followed by a significant decreasing trend in intensity during most the XVIIth and XVIIIth centuries. This evolution does not satisfactorily fit with the expected intensity values for France derived from geomagnetic field models relying on a different evolution of the axial dipole

  1. Determination of Two-Liquid Mixture Composition by Assessing Dielectric Parameters 1. Precise Measuring System / Divu Šķidrumu Maisījuma Sastāva Noteikšana, Izvērtējot to Dielektriskos Parametrus 1. Precīza Mērīšanas Sistēma

    NASA Astrophysics Data System (ADS)

    Vilitis, O.; Shipkovs, P.; Merkulovs, D.

    2013-08-01

    Concentration measurements are important in bioethanol industries, in the R&D areas, for chemical, medical and microbiological analyses and processing as well as for diagnostics, manufacturing, etc. The overview shows development of the structural design of a system for measuring the concentration of solutions and mixtures consisting of two dielectric liquids. The basic principles of the system's design are given along with relevant equations. The concentration of dielectric liquids is measured using devices with capacitive sensors (1-300 pF). The operational frequency of the developed measuring system is 100.000 kHz. Configuration of the system excludes some errors usually arising at measurements, and broadens its applicability. For testing, the system was calibrated for measuring the concentration of anhydrous ethanol + de-ionized water mixture. Experimental results have shown a stable resolution of ±0.005 pF at measuring the sensor capacitance and a reproducible resolution better than ±0.01% at measuring the ethanol volume concentration Rakstā esam parādījuši iespējas izveidot augstas precizitātes, kompaktu, lētu un ērtu lietošanai dielektrisku šķidrumu mērīšanas sistēmu koncentrācijas noteikšanai. Šī sistēma ir piemērojama kapacitīviem sensoriem, kuru kapacitāte ir atkarīga no sensora izveidojuma kā arī mērāmā šķidruma dielektriskās konstantes vērtības, un kapacitāte var tikt noteikta pie frekvences 100,000 kHz robežās no 1 F līdz 300 pF. Mērīšanas sistēmas pārbaudei, sistēma tika kalibrēta etanola koncentrācijas mērīšanai tilpuma procentos sertificēta bezūdens etanola un dejonizēta ūdens maisījumiem. Pārbaužu rezultāti pierādīja, ka sensora kapacitātes vērtības ir stabili nosakāmas ar izšķirtspēju ne mazāku par ±0,005 pF. Sensora kapacitāšu vērtībām atbilstošā etanola tilpuma koncentrācijas atkārtojamu mērījumu izšķirtspēja visā mērīšanas diapazonā nebija mazāka par ±0

  2. Influence of bed surface changes on snow avalanche simulation

    NASA Astrophysics Data System (ADS)

    Fischer, Jan-Thomas; Issler, Dieter

    2014-05-01

    Gravitational flows, such as snow avalanches, are often modeled employing the shallowness assumption. The driving gravitational force has a first order effect on the dynamics of the flow, especially in complex terrain. Under suitable conditions, erosion and deposition during passage of the flow may change the bed surface by a similar amount as the flow depth itself. The accompanying changes of local slope angle and curvature are particularly significant at the side margins of the flow, where they may induce self-channeling and levée formation. Generally, one ought to expect visible effects wherever the flow depth and velocity are small, e.g., in deposition zones. Most current numerical models in practical use neglect this effect. In order to study the importance of these effects in typical applications, we modified the quasi-3D (depth-averaged) code MoT-Voellmy, which implements the well-known Voellmy friction law that is traditionally used in hazard mapping: The bed shear stress is given by τiz(h,u) = -ui(μgh cosθ+ ku2), ||u|| (1) with μ = O(0.1...0.5) and k = O(10-3...10-2) the dimensionless friction and drag coefficients, respectively. The leading curvature effects, i.e., extra friction due to centrifugal normal forces, are taken into account. The mass and momentum balances are solved by the (simplified) method of transport on a grid whose cells are squares when projected onto the horizontal plane. The direction of depth-averaging is everywhere perpendicular to the topographic surface. A simple erosion model is used. The erosion formula is based on the assumption that the snow cover behaves as a perfectly brittle solid with shear strength τc, above which it instantaneously fails. The erosion rate is derived from the balance of momentum across the interface between bed and flow, where there is a discontinuity of the shear stress, which is given by equation 1 just above the interface and by τc just below it according to the assumptions. This immediately

  3. Textural and petrological characteristics of ultrahigh-pressure chromitites, indicating a mantle recycling origin?

    NASA Astrophysics Data System (ADS)

    Arai, Shoji; Miura, Makoto; Yamamoto, Shinji; Shmelev, Vladimir

    2013-04-01

    examine the nodular-textured UHP chromitites from Luobusa (Yamamoto et al., 2009) to compare with nodular-textured chromities from the Oman ophiolite, which we consider as of typical low-P origin. They are completely different. The chromite nodule is an aggregate of subhedral to euhedral chromian spinel grains with interstitial olivine from the Oman chromitite, but is apparently an oval-shaped spinel grain cut by fractures filled with olivine (= COF (chromite cut by olivine-filled fractures) texture). Similar COF texture was confirmed from possible UHP chromitites from Ray-Iz ophiolite, the Polar Urals (Trumbull et al., 2009; Shmelev, 2011). Chromian spinel is totally free from pargasite and other inclusions in UHP chromitites (Miura et al., 2012). Olivine in chromitites with the COF texture is characterized by exceptionally high NiO contents (up to more than 1 wt%). These characteristics are apparently consistent with the deep recycling origin for the UHP chromitites. The COF texture is a result of a rheological contrast between olivine and chromian spinel during the travel of the chromitite in the mantle. The high Ni character of olivine is due to diffusion of Ni from chromian spinel during the recycling. The primary nodular-textured chromitite of low-P igneous origin can be basically preserved even after deep recycling, although compaction and possible phase transformation had occurred.

  4. Experimental investigations of the absorption and dispersion profiles of a strongly driven transition: Two-level system with a weak probe

    NASA Astrophysics Data System (ADS)

    Wei, Changjiang; Manson, Neil B.

    1994-06-01

    The paper reports on experimental investigations of absorption and dispersion profiles of a strongly driven hyperfine transition at various pump field intensities and detunings when probed by a weak field. The transition lies at 5.4 MHz and corresponds to the Iz=0⇆-1 nuclear magnetic transition within the electron spin singlet of the 3A ground state of the nitrogen-vacancy (NV) center in diamond. The inhomogeneous linewidth of the transition is 8 kHz whereas the homogeneous linewidth is 2.7 kHz, which is a factor of 3 larger than that limited by the population relaxations. The absorption and dispersion are obtained using Raman heterodyne detection, a coherent optically detected magnetic-resonance technique. Measurements are performed in a situation where there is an anticrossing of the ground-state electron-spin levels, as this leads to an enhancement of the hyperfine transition strengths and the optical sensitivity. Weak probe fields with Rabi frequency <0.6 kHz could then be used. The absorption and dispersion profiles were recorded for on-resonance pump fields of various strengths with Rabi frequencies of 0, 2.1, 3.7, 6.6, 11.8, and 21 kHz. In addition, the responses were recorded for an off-resonance field with a Rabi frequency of 55 kHz and detunings between -40 and +40 kHz. The corresponding response of an idealized driven two-level system has been calculated using an established density-matrix equation of motion formalism. When normalized to the profiles with no driving field, the calculated and experimental profiles are in excellent agreement. The nitrogen-vacancy system provides a very clear experimental illustration of a driven two-level system and some aspects are highlighted. For on-resonance pumping, the dispersion profile consists of a positive and a negative absorptionlike peak separated by twice the pump Rabi frequency. The peaks correspond to a significant signal strength (index of refraction) whereas at the frequency of the peaks in dispersion

  5. [Bacteremia caused by ciprofloxacin-resistant Salmonella serotype Kentucky: a case report and the review of literature].

    PubMed

    Müderris, Tuba; Ürkmez, Fatma Yekta; Küçüker, Şeref Alp; Sağlam, Muhammet Fethi; Yılmaz, Gül Ruhsar; Güner, Rahmet; Güleşen, Revasiye; Açıkgöz, Ziya Cibali

    2016-10-01

    Salmonella infections can be seen in four clinical types, namely gastroenteritis, bacteremia/sepsis, enteric fever and carriage. These infections can result in uncomplicated diarrhea in most cases, but can lead to invasive disease requiring antimicrobial therapy and can be life-threatening in elderly or immunocomprimised patients. Broad-spectrum cephalosporins and fluoroquinolones are crucial options in the treatment of the invasive infections. Ciprofloxacin resistance is rarely seen in non-typhoid Salmonella enterica isolates, and only in S. Typhimurium, S. Choleraesuis and S. Schwarzengrund. In this report, we aimed to discuss a patient infected with ciprofloxacin-resistant Salmonella Kentucky under the light of data from our country and the world. A 52-year-old male patient wih acute myocardial infarction was hospitalized in intensive care unit of cardiovasculer surgery for left ventricular assist device (LVAD) implantation for the treatment of left ventricular disfunction. On the seventh day of LVAD and coronary artery bypass grafting (CABG), the patient presented high fever and productive cough. His physical examination revealed hyperemia around the insertion point of right jugular central venous catheter (CVC) and a serous discharge from the insertion point of LVAD located just below the inferior edge of sternum. Empiric IV cefoperazone/sulbactam (SCF) therapy was started with the prediagnosis of pneumonia and bloodstream infection. The blood samples taken from peripheral veins and CVC, and swabs taken from LVAD insertion point for culture when the patient was febrile, revealed the growth of bacteria with S type and lactose-negative colonies on EMB and SS media. Biochemical characteristics of the isolate were as follows: lactose fermentation negative, H2S positive, IMVIC (-,+,-,+), urease negative, lysine/ornithine decarboxylase positive and motile. The bacteria was then identified as Salmonella enterica serotype Kentucky (8,20;i;z6) by agglutination tests

  6. Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics

    PubMed Central

    2012-01-01

    predicts the presence of novel trafficking-related components, and also the organizational logic that allows toxin diversification through recombination. Domain architecture and protein-length analysis revealed that these toxins might be deployed as secreted factors, through directed injection, or via inter-cellular contact facilitated by filamentous structures formed by RHS/YD, filamentous hemagglutinin and other repeats. Phyletic pattern and life-style analysis indicate that polymorphic toxins and polyimmunity loci participate in cooperative behavior and facultative ‘cheating’ in several ecosystems such as the human oral cavity and soil. Multiple domains from these systems have also been repeatedly transferred to eukaryotes and their viruses, such as the nucleo-cytoplasmic large DNA viruses. Conclusions Along with a comprehensive inventory of toxins and immunity proteins, we present several testable predictions regarding active sites and catalytic mechanisms of toxins, their processing and trafficking and their role in intra-specific and inter-specific interactions between bacteria. These systems provide insights regarding the emergence of key systems at different points in eukaryotic evolution, such as ADP ribosylation, interaction of myosin VI with cargo proteins, mediation of apoptosis, hyphal heteroincompatibility, hedgehog signaling, arthropod toxins, cell-cell interaction molecules like teneurins and different signaling messengers. Reviewers This article was reviewed by AM, FE and IZ. PMID:22731697

  7. Clustering analysis of high-redshift luminous red galaxies in Stripe 82

    NASA Astrophysics Data System (ADS)

    Nikoloudakis, N.; Shanks, T.; Sawangwit, U.

    2013-03-01

    We present a clustering analysis of luminous red galaxies (LRGs) in Stripe 82 from the Sloan Digital Sky Survey (SDSS). We study the angular two-point autocorrelation function, w(θ), of a selected sample of over 130 000 LRG candidates via colour-cut selections in izK with the K-band coverage coming from UKIRT (United Kingdom Infrared Telescope) Infrared Deep Sky Survey (UKIDSS) Large Area Survey (LAS). We have used the cross-correlation technique of Newman to establish the redshift distribution of the LRGs. Cross-correlating them with SDSS quasi-stellar objects (QSOs), MegaZ-LRGs and DEEP Extragalactic Evolutionary Probe 2 (DEEP2) galaxies, implies an average redshift of the LRGs to be z ≈ 1 with space density, ng ≈ 3.20 ± 0.16 × 10-4 h3 Mpc-3. For θ ≤ 10 arcmin (corresponding to ≈10 h-1 Mpc), the LRG w(θ) significantly deviates from a conventional single power law as noted by previous clustering studies of highly biased and luminous galaxies. A double power law with a break at rb ≈ 2.4 h-1 Mpc fits the data better, with best-fitting scale length, r0, 1 = 7.63 ± 0.27 h-1 Mpc and slope γ1 = 2.01 ± 0.02 at small scales and r0, 2 = 9.92 ± 0.40 h-1 Mpc and γ2 = 1.64 ± 0.04 at large scales. Due to the flat slope at large scales, we find that a standard Λ cold dark matter (Λ CDM) linear model is accepted only at 2-3σ, with the best-fitting bias factor, b = 2.74 ± 0.07. We also fitted the halo occupation distribution (HOD) models to compare our measurements with the predictions of the dark matter clustering. The effective halo mass of Stripe 82 LRGs is estimated as Meff = 3.3 ± 0.6 × 1013 h-1 M⊙. But at large scales, the current HOD models did not help explain the power excess in the clustering signal. We then compare the w(θ) results to the results of Sawangwit et al. from three samples of photometrically selected LRGs at lower redshifts to measure clustering evolution. We find that a long-lived model may be a poorer fit than at lower

  8. Geological and geophysical activities at Spallanzani Science Department (Liceo Scientifico Statale "Lazzaro Spallanzani" - Tivoli, Italy)

    NASA Astrophysics Data System (ADS)

    Favale, T.; De Angelis, F.; De Filippis, L.

    2012-04-01

    The high school Liceo Scientifico "Lazzaro Spallanzani" at Tivoli (Rome) has been fully involved in the study of geological and geophysical features of the town of Tivoli and the surrounding area in the last twelve years. Objective of this activity is to promote the knowledge of the local territory from the geological point of view. Main activities: • School year 2001-2002: Setting up inside the school building of a Geological Museum focusing on "Geological Evolution of Latium, Central Italy" (in collaboration with colleagues M. Mancini, and A. Pierangeli). • March, 15, 2001: Conference of Environmental Geology. Lecturer: Prof. Raniero Massoli Novelli, L'Aquila University and Società Italiana di Geologia Ambientale. • School years 2001-2002 and 2002-2003: Earth Sciences course for students "Brittle deformation and tectonic stress in Tivoli area". • November, 2003: Conference of Geology, GIS and Remote Sensing. Lecturers: Prof. Maurizio Parotto and Dr Alessandro Cecili (Roma Tre University, Rome), and Dr Stefano Pignotti (Istituto Nazionale per la Ricerca sulla Montagna, Rome). • November, 2003, 2004 and 2005: GIS DAY, organized in collaboration with ESRI Italia. • School year 2006-2007: Earth Sciences course for students "Acque Albule basin and the Travertine of Tivoli, Latium, Central Italy" (focus on travertine formation). • School year 2010-2011: Earth Sciences course for students "Acque Albule basin and the Travertine of Tivoli. Geology, Hydrogeology and Microbiology of the basin, Latium, Central Italy" (focus on thermal springs and spa). In the period 2009-2010 a seismic station with three channels, currently working, was designed and built in our school by the science teachers Felice De Angelis and Tomaso Favale. Our seismic station (code name LTTV) is part of Italian Experimental Seismic Network (IESN) with identification code IZ (international database IRIS-ISC). The three drums are online in real time on websites http

  9. Operative and technological management of super-large united power grids: lessons of major world's blackouts

    NASA Astrophysics Data System (ADS)

    Brinkis, K.; Kreslins, V.; Mutule, A.

    2014-02-01

    Power system (PS) blackouts still persist worldwide, evidencing that the existing protective structures need to be improved. The discussed requirements and criteria to be met for joint synchronous operation of large and super-large united PSs should be based on close co-ordination of operative and technological management of all PSs involved in order to ensure secure and stable electricity supply and minimise or avoid the threat of a total PS blackout. The authors analyse the July 2012 India blackout - the largest power outage in history, which affected over 620 million people, i.e. half of India's population and spread across its 22 states. The analysis is of a general character, being applicable also to similar blackouts that have occurred in Europe and worldwide since 2003. The authors summarise and develop the main principles and methods of operative and technological management aimed at preventing total blackouts in large and super-large PSs. Neskatoties uz sasniegumiem elektroenerģētikas jomā un energosistēmu nepārtrauktu modernizāciju, pasaulē regulāri notiek sabrukumu avārijas. Rakstā apskatīti lielu un superlielu energosistēmu apvienību savstarpējas sinhronas darbības nodrošinājuma prasības un kritēriji, kas pamatojas uz operatīvās un tehnoloģiskās vadības ciešu koordināciju starp energosistēmām. Savstarpējas sinhronas darbības nodrošinājuma prasībām un kritērijiem ir izšķiroša nozīme, lai panāktu elektroapgādes drošumu un stabilitāti katrā energosistēmā, kas darbojas apvienotas energosistēmas sastāvā. Šo prasību un kritēriju ievērošana sekmē totālo avāriju izcelšanās iespēju samazināšanu un to novēršanu. Indijas 2012.gada totālo avāriju un citu analogo avāriju Eiropā un Amerikā analīze un izvērtējums laika posmā no 2003.gada, deva iespēju apkopot un izstrādāt lielu un superlielu energosistēmu operatīvās un tehnoloģiskās vadības principus un metodoloģiju, lai novērstu vai

  10. Climatic record of the Iberian peninsula from lake Moncortes' sediments

    NASA Astrophysics Data System (ADS)

    Cao, Min; Huguet, Carme; Rull, Valenti; Valero, Blas; Rosell-Mele, Antoni

    2014-05-01

    .19km2. Lake Moncortes is situated at 1065 m above sea level, has an average temperature of 10ºC (minimum 3 and maximum 16ºC) and a mean annual precipitation of 770mm. We used the MBT/CBT (Weijers et al. 2007) proxy of pH and terrestrial temperature and the TEX86 temperature proxy (Schouten et al. 2002) to estimate changes in and around the lake. Both proxies are based on the glycerol dialkyl glycerol tetraethers (GDGTs) of archaea (isoprenoid GDGTs) and bacteria (branched GDGTs) origin. We also measured soils surrounding the lake (Menges et al. 2013) in order to establish end-members for the proxies as well as organic matter transport. Data on n-alkane isotopes will help establish hydrographic regime changes. We observe changes in temperature and humidity consistent with those on teh northern hemisphere. J. Menges, C. Huguet, J.M. Alcañiz, S. Fietz, D. Sachse, A. Rosell-Melé Biogechemistry discussions (2013), BGD bg-2013-198. S. Schouten, E.C. Hopmans, E. Schefuss, J.S.S. Damste, Earth and Planetary Science Letters 204(2002) 265-274 J.W.H. Weijers, S. Schouten, J.S.S. Damste, Geochimica Et Cosmochimica Acta 71(2007) A1098-A1098.

  11. The massive galaxy cluster XMMU J1230.3+1339 at z ˜ 1: colour-magnitude relation, Butcher-Oemler effect, X-ray and weak lensing mass estimates

    NASA Astrophysics Data System (ADS)

    Lerchster, M.; Seitz, S.; Brimioulle, F.; Fassbender, R.; Rovilos, M.; Böhringer, H.; Pierini, D.; Kilbinger, M.; Finoguenov, A.; Quintana, H.; Bender, R.

    2011-03-01

    We present results from the multiwavelength study of XMMU J1230.3+1339 at z˜ 1. We analyse deep multiband wide-field images from the Large Binocular Telescope (LBT), multi-object spectroscopy observations from VLT, as well as space-based serendipitous observations, from the GALEX and Chandra X-ray observatories. We apply a Bayesian photometric redshift code to derive the redshifts using the far-UV (FUV), near-UV (NUV) and the deep U, B, V, r, i, z data. We make further use of spectroscopic data from FORS2 to calibrate our photometric redshifts, and investigate the photometric and spectral properties of the early-type galaxies. We achieve an accuracy of ▵z/(1 +z)= 0.07 (0.04) and the fraction of catastrophic outliers is η= 13 (0) per cent, when using all (secure) spectroscopic data, respectively. The i-z against z colour-magnitude relation of the photo-z members shows a tight red sequence with a zero-point of 0.935 mag, and slope equal to -0.027. We observe evidence for a truncation at the faint end of the red-cluster-sequence and the Butcher-Oemler effect, finding a fraction of blue galaxies fb≈ 0.5. Further, we conduct a weak lensing analysis of the deep 26 × 26 arcmin r-band LBC image. The observed shear is fitted with a Single-Isothermal-Sphere and a Navarro-Frenk-White model to obtain the velocity dispersion and the model parameters, respectively. Our best-fitting values are, for the velocity dispersion σSIS= 1308 ± 284 km s-1, concentration parameter c= 4.0+14-2 and scale radius rs= 345+50-57 kpc. From a 38 ks Chandra X-ray observation we obtain an independent estimate of the cluster mass. In addition, we create a signal-to-noise ratio (S/N) map for the detection of the matter mass distribution of the cluster using the mass-aperture technique. We find excellent agreement of the mass concentration identified with weak lensing and the X-ray surface brightness. Combining our mass estimates from the kinematic, X-ray and weak lensing analyses we obtain a

  12. Digital Base Band Converter As Radar Vlbi Backend / Dbbc Kā Ciparošanas Sistēma Radara Vlbi Novērojumiem

    NASA Astrophysics Data System (ADS)

    Tuccari, G.; Bezrukovs, Vl.; Nechaeva, M.

    2012-12-01

    can then allow exploring easily the desired range of search for unknown or not fully determined orbit objects. These features make Radar VLBI personality most useful in the space debris measurements. DBBC sistēma izstrādāta Noto Radioastronomijas institūtā. Sistēmas galvenaisuzdevums - palielināt visa Eiropas VLBI tīkla jutību - realizēts, palielinotvisas novērojamās joslas platumu un pielietojot ciparu signālu apstrādes metodes.Izejas datu plūsma palielināta no 1 līdz 4 Gbps katram radioteleskopam un visasoperācijas, kas saistītas ar signālu apstrādi (frekvences pārveidošana, pastiprinājums,iekšējie ģeneratori, utt.), realizētas digitālā formā, kas ļauj iegūt nozīmīgusuzlabojumus atkārtojamībā, precizitātē, vienkāršībā, nemaz neminot vispārzināmāspriekšrocības, ko nodrošina digitālo tehnoloģiju izmantošana. Maksimālā ieejassignāla frekvenču josla ir 3.5 GHz, un momentānais joslas platums ir līdz 1 GHz uzkatru no astoņiem iespējamajiem RF/IF kanāliem. Šī datu reģistrācijas sistēma irļoti veiktspējīga platforma ne tikai EVN, bet arī citiem radioastronomijas pielietojumiem,un papildus tiek izstrādāta vesela virkne programmatūras pakotņu, kasvēl vairāk paplašina sistēmas funkcionalitāti. Tas ietver PFB (Polifāzes FiltruBanka) uztvērējus "Spectra”, kas piemēroti augstas izšķirtspējas spektroskopijasvajadzībām. Papildus realizēts jaunas programmatūras risinājums, ar mērķiizmantot DBBC sistēmu kā daudzfunkcionālu datu ciparošanas iekārtu, kasizmantojama bistatiskiem radara novērojumiem, tai skaitā arī radara VLBInovērojumiem. Šāda veida novērojumos tiek pētīta kosmisko atlūzu populācija,nodrošinot iespēju detektēt pat centimetra

  13. A Survey of z>5.8 Quasars in the Sloan Digital Sky Survey. I. Discovery of Three New Quasars and the Spatial Density of Luminous Quasars at z~6

    NASA Astrophysics Data System (ADS)

    Fan, Xiaohui; Narayanan, Vijay K.; Lupton, Robert H.; Strauss, Michael A.; Knapp, Gillian R.; Becker, Robert H.; White, Richard L.; Pentericci, Laura; Leggett, S. K.; Haiman, Zoltán; Gunn, James E.; Ivezić, Željko; Schneider, Donald P.; Anderson, Scott F.; Brinkmann, J.; Bahcall, Neta A.; Connolly, Andrew J.; Csabai, István; Doi, Mamoru; Fukugita, Masataka; Geballe, Tom; Grebel, Eva K.; Harbeck, Daniel; Hennessy, Gregory; Lamb, Don Q.; Miknaitis, Gajus; Munn, Jeffrey A.; Nichol, Robert; Okamura, Sadanori; Pier, Jeffrey R.; Prada, Francisco; Richards, Gordon T.; Szalay, Alex; York, Donald G.

    2001-12-01

    We present the results from a survey of i-dropout objects selected from ~1550 deg2 of multicolor imaging data from the Sloan Digital Sky Survey to search for luminous quasars at z>~5.8. Objects with i*-z*>2.2 and z*<20.2 are selected, and follow-up J-band photometry is used to separate L- and T-type cool dwarfs from high-redshift quasars. We describe the discovery of three new quasars, SDSSp J083643.85+005453.3 (z=5.82), J130608.26+035626.3 (z=5.99), and J103027.10+052455.0 (z=6.28). The quasar SDSSp J083643.85+005453.3 is a radio source with flux of 1.1 mJy at 20 cm. The spectra of all three quasars show strong and broad Lyα+N V emission lines and very strong Lyα forest absorption, with a mean continuum decrement DA>0.90. The ARC 3.5 m spectrum of SDSSp J103027.10+052455.0 shows that over a range of ~300 Å immediately blueward of the Lyα emission, the average transmitted flux is only 0.003+/-0.020 times that of the continuum level, consistent with zero flux over a ~300 Å range of the Lyα forest region and suggesting a tentative detection of the complete Gunn-Peterson trough. The existence of strong metal lines in the quasar spectra suggests early metal enrichment in the quasar environment. The three new objects, together with the previously published z=5.8 quasar SDSSp J104433.04-012502.2, form a complete color-selected flux-limited sample at z>~5.8. We estimate the selection function of this sample, taking into account the estimated variations in the quasar spectral energy distribution, as well as observational photometric errors. We find that at z=6, the comoving density of luminous quasars at M1450<-26.8 (H0=50 km s-1 Mpc-1, Ω=1) is 1.1×10-9 Mpc-3. This is a factor of ~2 lower than that at z~5 and is consistent with an extrapolation of the observed quasar evolution at z<5. Using the current sample, we discuss the constraint on the shape of the quasar luminosity function and the implications for the contribution of quasars to the ionizing background at z

  14. HUBBLE'S PANORAMIC PORTRAIT OF A VAST STAR-FORMING REGION

    NASA Technical Reports Server (NTRS)

    2002-01-01

    giant shell, devoid of gas and dust. Still later, all of the most massive stars and gas will have disappeared from the entire region. Only older, less massive stars will remain in a region cleared of gas and dust. The mosaic image of 30 Doradus consists of five overlapping pictures taken between January 1994 and September 2000 by Hubble's Wide Field and Planetary Camera 2. Several color filters were used to enhance important details in the stars and the nebula. Blue corresponds to the hot stars. The greenish color denotes hot gas energized by the central cluster of stars. Pink depicts the glowing edges of the gas and dust clouds facing the cluster, which are being bombarded by winds and radiation. Reddish-brown represents the cooler surfaces of the clouds, which are not receiving direct radiation from the central cluster. Credits: NASA, N. Walborn and J. Ma`iz-Apell`aniz (Space Telescope Science Institute, Baltimore, MD), R. Barb`a (La Plata Observatory, La Plata, Argentina)

  15. The TRAPPIST comet survey

    NASA Astrophysics Data System (ADS)

    Jehin, E.; Opitom, C.; Manfroid, J.; Hutsemékers, D.; Gillon, M.

    2014-07-01

    TRAPPIST (TRAnsiting Planets and PlanetesImals Small Telescope) is a 60-cm robotic telescope that has been installed in June 2010 at the ESO La Silla Observatory [1]. Operated from Liège (Belgium) it is devoted to the detection and characterisation of exoplanets and to the study of comets and other small bodies in the Solar System. We describe here the hardware and the goals of the project and give an overview of the comet production rates monitoring after three years of operations. The telescope and observatory --- TRAPPIST's optical tube unit is a Ritchey-Chretien 0.6 meter telescope with a focal length of 4.8 meter. It is associated with a German equatorial mount that is, thanks to its direct drive system, extremely fast (up to 50 deg/s), accurate (tracking accuracy without autoguider better than 2'' in 10 min), and free of periodic error. The instrument is a Peltier cooled commercial camera equipped with a Fairchild 3041 back-illuminated 2k×2k chip. The pixel scale is 0.64''/pixel. Three read-out modes are available, the shortest read-out time being 2s. The total field of view of the camera is 22'×22'. It is associated to a custom-made dual filter wheel. One of the filter wheel contains broad band filters (Johnson B, V, R, Cousins Ic, Sloan z, and a special I+z filter), while the other contains the narrow-band NASA HB cometary filters (OH, NH, CN, CO+, C3, and C2 gaseous species; UC, BC, GC and RC solar continuum windows and a NaI D filter) [2]. The telescope is protected by a 5 meter diameter dome that was totally refurbished and automatized. The observatory is fully robotic and equipped with a weather station, an UPS and webcams. The la Silla site is excellent with more than 300 clear nights per year and the telescope has proven to be very reliable with a small amount of technical downtime. Comet monitoring --- For relatively bright comets (V < 12) we measure several times a week the gaseous production rates (using a Haser model) and the spatial

  16. VizieR Online Data Catalog: OCARS catalog second version (Malkin, 2016)

    NASA Astrophysics Data System (ADS)

    Malkin, Z. M.

    2016-11-01

    Unlike the first version, supported in 2007-2015, the second version of the OCARS catalog includes three files: ocars.txt is the main file containing the source coordinates, source types, redshifts, and approximate magnitudes, together with commentary; this file corresponds to the first version of the OCARS catalog; ocars_m.txt contains photometric data in the 13 uUBgV rRiIzJHK bands; ocars_n.txt contains a table of corresponding source names in various catalogs; currently, only cross-identifications with IVS programs4 and the LQAC catalog [9] are included; The list of objects included in the OCARS catalog is formed from various astrometric and geodeticVLBI programs and catalogs in the following order: - sources in the ICRF2 [2]; - other sources observed in the framework of IVS programs; - sources from the NASA Goddard VLBI group catalog5 ; - sources from the RFC catalog,6 which is the most complete astrometric catalog of radio sources, is updated each quarter, and contributed more than half the OCARS objects; the latest version of OCARS used the RFC-2016a catalog based on observations obtained in 1980-2015 as part of IVS and other radio astrometric programs [19-31]; - sources from the literature. Optical Characteristics of Astrometric Radio Sources (OCARS) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Last revised: 27-NOV-2016 Latest update: - removed 30+ RFC sources not identified in NED and optics - removed rather long detailed statistics table, which seems to be not interested for most of users; it is always available on request - a few additions and amendments E-mail alerts about updates are available on request. URL of this file is http://www

  17. Analysis of geomagnetic data and cosmic ray variations in periods of magnetic perturbations

    NASA Astrophysics Data System (ADS)

    Mandrikova, Oksana; Zalyaev, Timur; Solovev, Igor; Shevtsov, Boris

    field and predicting strong magnetic storms. Using the combination of the wavelet transform and neural networks, we have developed a technique of approximating the time variation of cosmic-ray data. This technique allows us to perform detailed analysis of geomagnetic data and detect anomalies in periods of high solar activity. Approximations of large-scale time variation components of cosmic-ray data have been obtained in the following form: [ c_{j,n+1}(t)=\\varphi^3_m Biggl (sum_i omega^3_{mi}\\varphi^2_i biggl (sum_l omega^2_{il}\\varphi^1_lBigl(sum_n omega^1_{ln}c_{j,n}(t)Bigr )biggr ) Biggr ) ] where c_{j,n}=< y, phi_{j,n} > ;phi_{j,n}=2(j/2) phi(2(j(t)-n)) is the scaling function, omega(1_{ln}) are the weights of the neurons of the network input layer l,omega(2_{il}) are the weights of the neurons of the network hidden layer i, omega(3_{mi}) are the weights of the neurons of the network output layer m, varphi(1_l(z)=varphi^2_i(z)=(2)/(1+exp(-2z))-1) ,varphi(3_m(z)) =a*z+b. Coefficients c_{j,n} are the result of transforming of the original function y to the space with the scale j. Analysis of long geomagnetic data from the Paratunka observatory (Kamchatka region, Russia) provided quantitative estimates of the storminess degree of the geomagnetic field before and during magnetic storms. Furthermore, we have managed to identify local weak increases of the field perturbations prior to the main phase of storms. The intensity of field perturbations rises on average 2.5 days before the onset of a storm. Abnormal time periods connected with increased solar activity have been detected in the flow of cosmic rays. Comparison of the results with the geomagnetic data has shown that the anomalies in the cosmic ray variations occur in periods of strong geomagnetic perturbations. The tools and techniques suggested in the present work, together with other methods of data -analysis will help forecast space weather, estimate more accurately the condition of the Earth’s magnetic

  18. Biorefinery Technologies for Biomass Conversion Into Chemicals and Fuels Towards Zero Emissions (Review) / Nulles Emisiju Princips Biomasas Konversijas Tehnoloģijās Aizstājot Fosilos Resursus (Pārskata Raksts)

    NASA Astrophysics Data System (ADS)

    Gravitis, J.; Abolins, J.

    2013-10-01

    Exhausting of world resources, increasing pollution, and climate change are compelling the shift of the world economy from continuous growth to a kind of economy based on integration of technologies into zero emissions production systems. Transition from non-renewable fossil resources to renewable resources provided by solar radiation and the current processes in biosphere is seen in the bio-refinery approach - replacing crude oil refineries by biomass refineries. Biotechnology and nano-technologies are getting accepted as important players along with conventional biomass refinery technologies. Systems design is a significant element in the integration of bio-refinery technologies in clusters. A number of case-studies, steam explosion auto-hydrolysis (SEA) in particular, are reviewed to demonstrate conversion of biomass into value-added chemicals and fuels. Analysis of energy flows is made as part of modelling the SEA processes, the eMergy (energy memory) approach and sustainability indices being applied to assess environmental impacts. Resursu izsīkums, vides piesārņojums un globāla mēroga klimatiskās izmaiņas ir civilizācijas izdzīvošanai būtiski faktori, kas virza pasaules ekonomikas pārmaiņas, atsakoties no nepārtrauktas izaugsmes idejas par labu tādai ekonomikai, kas balstās uz atjaunojošamies resursiem un dažādu tehnoloģiju integrācijemisiju principam atbilstošās ražošanas sistēmās. Saules radiācijas ierosinātajos planētas biosfērā notiekošajos procesos radīto organisko vielu pārstrādes kompleksi, kas operē ievērojot sabalansētu nulles emisiju principu, tiek uzlūkoti kā tās ekonomiskās (ražošanas) struktūras, kurām jānodrošina pāreja uz atjaunojošos resursu izmantošanu, aizstājot esošās fosilo resursu (naftas, ogļu) pārstrādes rūpnīcas. Līdzās jau apgūtajām biomasas rafinēšanas tehnoloģijām svarīga un pieaugoša loma ekonomiskās sistēmas resursu bāzes nomaiņā ir bio- un nanotehnolo