Organizing integrated care in a university hospital: application of a conceptual framework.

PubMed

Axelsson, Runo; Axelsson, Susanna Bihari; Gustafsson, Jeppe; Seemann, Janne

2014-04-01

As a result of New Public Management, a number of industrial models of quality management have been implemented in health care, mainly in hospitals. At the same time, the concept of integrated care has been developed within other parts of the health sector. The aim of the article is to discuss the relevance of integrated care for hospitals. The discussion is based on application of a conceptual framework outlining a number of organizational models of integrated care. These models are illustrated in a case study of a Danish university hospital implementing a new organization for improving the patient flows of the hospital. The study of the reorganization is based mainly on qualitative data from individual and focus group interviews. The new organization of the university hospital can be regarded as a matrix structure combining a vertical integration of clinical departments with a horizontal integration of patient flows. This structure has elements of both interprofessional and interorganizational integration. A strong focus on teamwork, meetings and information exchange is combined with elements of case management and co-location. It seems that integrated care can be a relevant concept for a hospital. Although the organizational models may challenge established professional boundaries and financial control systems, this concept can be a more promising way to improve the quality of care than the industrial models that have been imported into health care. This application of the concept may also contribute to widen the field of integrated care.

Concept for maritime near-surface surveillance using water Raman scattering

DOE PAGES

Shokair, Isaac R.; Johnson, Mark S.; Schmitt, Randal L.; ...

2018-06-08

Here, we discuss a maritime surveillance and detection concept based on Raman scattering of water molecules. Using a range-gated scanning lidar that detects Raman scattered photons from water, the absence or change of signal indicates the presence of a non-water object. With sufficient spatial resolution, a two-dimensional outline of the object can be generated by the scanning lidar. Because Raman scattering is an inelastic process with a relatively large wavelength shift for water, this concept avoids the often problematic elastic scattering for objects at or very close to the water surface or from the bottom surface for shallow waters. Themore » maximum detection depth for this concept is limited by the attenuation of the excitation and return Raman light in water. If excitation in the UV is used, fluorescence can be used for discrimination between organic and non-organic objects. In this paper, we present a lidar model for this concept and discuss results of proof-of-concept measurements. Using published cross section values, the model and measurements are in reasonable agreement and show that a sufficient number of Raman photons can be generated for modest lidar parameters to make this concept useful for near-surface detection.« less

Concept for maritime near-surface surveillance using water Raman scattering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shokair, Isaac R.; Johnson, Mark S.; Schmitt, Randal L.

Here, we discuss a maritime surveillance and detection concept based on Raman scattering of water molecules. Using a range-gated scanning lidar that detects Raman scattered photons from water, the absence or change of signal indicates the presence of a non-water object. With sufficient spatial resolution, a two-dimensional outline of the object can be generated by the scanning lidar. Because Raman scattering is an inelastic process with a relatively large wavelength shift for water, this concept avoids the often problematic elastic scattering for objects at or very close to the water surface or from the bottom surface for shallow waters. Themore » maximum detection depth for this concept is limited by the attenuation of the excitation and return Raman light in water. If excitation in the UV is used, fluorescence can be used for discrimination between organic and non-organic objects. In this paper, we present a lidar model for this concept and discuss results of proof-of-concept measurements. Using published cross section values, the model and measurements are in reasonable agreement and show that a sufficient number of Raman photons can be generated for modest lidar parameters to make this concept useful for near-surface detection.« less

Twitter's tweet method modelling and simulation

NASA Astrophysics Data System (ADS)

Sarlis, Apostolos S.; Sakas, Damianos P.; Vlachos, D. S.

2015-02-01

This paper seeks to purpose the concept of Twitter marketing methods. The tools that Twitter provides are modelled and simulated using iThink in the context of a Twitter media-marketing agency. The paper has leveraged the system's dynamic paradigm to conduct Facebook marketing tools and methods modelling, using iThink™ system to implement them. It uses the design science research methodology for the proof of concept of the models and modelling processes. The following models have been developed for a twitter marketing agent/company and tested in real circumstances and with real numbers. These models were finalized through a number of revisions and iterators of the design, develop, simulate, test and evaluate. It also addresses these methods that suit most organized promotion through targeting, to the Twitter social media service. The validity and usefulness of these Twitter marketing methods models for the day-to-day decision making are authenticated by the management of the company organization. It implements system dynamics concepts of Twitter marketing methods modelling and produce models of various Twitter marketing situations. The Tweet method that Twitter provides can be adjusted, depending on the situation, in order to maximize the profit of the company/agent.

Operational concepts and implementation strategies for the design configuration management process.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trauth, Sharon Lee

2007-05-01

This report describes operational concepts and implementation strategies for the Design Configuration Management Process (DCMP). It presents a process-based systems engineering model for the successful configuration management of the products generated during the operation of the design organization as a business entity. The DCMP model focuses on Pro/E and associated activities and information. It can serve as the framework for interconnecting all essential aspects of the product design business. A design operation scenario offers a sense of how to do business at a time when DCMP is second nature within the design organization.

Computer modeling in developmental biology: growing today, essential tomorrow.

PubMed

Sharpe, James

2017-12-01

D'Arcy Thompson was a true pioneer, applying mathematical concepts and analyses to the question of morphogenesis over 100 years ago. The centenary of his famous book, On Growth and Form , is therefore a great occasion on which to review the types of computer modeling now being pursued to understand the development of organs and organisms. Here, I present some of the latest modeling projects in the field, covering a wide range of developmental biology concepts, from molecular patterning to tissue morphogenesis. Rather than classifying them according to scientific question, or scale of problem, I focus instead on the different ways that modeling contributes to the scientific process and discuss the likely future of modeling in developmental biology. © 2017. Published by The Company of Biologists Ltd.

Chemistry Notes.

ERIC Educational Resources Information Center

School Science Review, 1981

1981-01-01

Describes 13 activities, experiments and demonstrations, including the preparation of iron (III) chloride, simple alpha-helix model, investigating camping gas, redox reactions of some organic compounds, a liquid crystal thermometer, and the oxidation number concept in organic chemistry. (JN)

Panarchy: Theory and Application

EPA Science Inventory

The concept of panarchy was introduced by Gunderson et al. (1995) and refined by Gunderson and Holling (2002) as a heuristic model to help explain complex changes in ecosystem processes and structures within and across scales of organization. The concept takes a complex systems a...

Menzerath-Altmann Law: Statistical Mechanical Interpretation as Applied to a Linguistic Organization

NASA Astrophysics Data System (ADS)

Eroglu, Sertac

2014-10-01

The distribution behavior described by the empirical Menzerath-Altmann law is frequently encountered during the self-organization of linguistic and non-linguistic natural organizations at various structural levels. This study presents a statistical mechanical derivation of the law based on the analogy between the classical particles of a statistical mechanical organization and the distinct words of a textual organization. The derived model, a transformed (generalized) form of the Menzerath-Altmann model, was termed as the statistical mechanical Menzerath-Altmann model. The derived model allows interpreting the model parameters in terms of physical concepts. We also propose that many organizations presenting the Menzerath-Altmann law behavior, whether linguistic or not, can be methodically examined by the transformed distribution model through the properly defined structure-dependent parameter and the energy associated states.

Organizing integrated care in a university hospital: application of a conceptual framework

PubMed Central

Axelsson, Runo; Axelsson, Susanna Bihari; Gustafsson, Jeppe; Seemann, Janne

2014-01-01

Background and aim As a result of New Public Management, a number of industrial models of quality management have been implemented in health care, mainly in hospitals. At the same time, the concept of integrated care has been developed within other parts of the health sector. The aim of the article is to discuss the relevance of integrated care for hospitals. Theory and methods The discussion is based on application of a conceptual framework outlining a number of organizational models of integrated care. These models are illustrated in a case study of a Danish university hospital implementing a new organization for improving the patient flows of the hospital. The study of the reorganization is based mainly on qualitative data from individual and focus group interviews. Results The new organization of the university hospital can be regarded as a matrix structure combining a vertical integration of clinical departments with a horizontal integration of patient flows. This structure has elements of both interprofessional and interorganizational integration. A strong focus on teamwork, meetings and information exchange is combined with elements of case management and co-location. Conclusions It seems that integrated care can be a relevant concept for a hospital. Although the organizational models may challenge established professional boundaries and financial control systems, this concept can be a more promising way to improve the quality of care than the industrial models that have been imported into health care. This application of the concept may also contribute to widen the field of integrated care. PMID:24966806

Validation and Refinement of a Pain Information Model from EHR Flowsheet Data.

PubMed

Westra, Bonnie L; Johnson, Steven G; Ali, Samira; Bavuso, Karen M; Cruz, Christopher A; Collins, Sarah; Furukawa, Meg; Hook, Mary L; LaFlamme, Anne; Lytle, Kay; Pruinelli, Lisiane; Rajchel, Tari; Settergren, Theresa Tess; Westman, Kathryn F; Whittenburg, Luann

2018-01-01

Secondary use of electronic health record (EHR) data can reduce costs of research and quality reporting. However, EHR data must be consistent within and across organizations. Flowsheet data provide a rich source of interprofessional data and represents a high volume of documentation; however, content is not standardized. Health care organizations design and implement customized content for different care areas creating duplicative data that is noncomparable. In a prior study, 10 information models (IMs) were derived from an EHR that included 2.4 million patients. There was a need to evaluate the generalizability of the models across organizations. The pain IM was selected for evaluation and refinement because pain is a commonly occurring problem associated with high costs for pain management. The purpose of our study was to validate and further refine a pain IM from EHR flowsheet data that standardizes pain concepts, definitions, and associated value sets for assessments, goals, interventions, and outcomes. A retrospective observational study was conducted using an iterative consensus-based approach to map, analyze, and evaluate data from 10 organizations. The aggregated metadata from the EHRs of 8 large health care organizations and the design build in 2 additional organizations represented flowsheet data from 6.6 million patients, 27 million encounters, and 683 million observations. The final pain IM has 30 concepts, 4 panels (classes), and 396 value set items. Results are built on Logical Observation Identifiers Names and Codes (LOINC) pain assessment terms and extend the need for additional terms to support interoperability. The resulting pain IM is a consensus model based on actual EHR documentation in the participating health systems. The IM captures the most important concepts related to pain. Schattauer GmbH Stuttgart.

Organ culture bioreactors--platforms to study human intervertebral disc degeneration and regenerative therapy.

PubMed

Gantenbein, Benjamin; Illien-Jünger, Svenja; Chan, Samantha C W; Walser, Jochen; Haglund, Lisbet; Ferguson, Stephen J; Iatridis, James C; Grad, Sibylle

2015-01-01

In recent decades the application of bioreactors has revolutionized the concept of culturing tissues and organs that require mechanical loading. In intervertebral disc (IVD) research, collaborative efforts of biomedical engineering, biology and mechatronics have led to the innovation of new loading devices that can maintain viable IVD organ explants from large animals and human cadavers in precisely defined nutritional and mechanical environments over extended culture periods. Particularly in spine and IVD research, these organ culture models offer appealing alternatives, as large bipedal animal models with naturally occurring IVD degeneration and a genetic background similar to the human condition do not exist. Latest research has demonstrated important concepts including the potential of homing of mesenchymal stem cells to nutritionally or mechanically stressed IVDs, and the regenerative potential of "smart" biomaterials for nucleus pulposus or annulus fibrosus repair. In this review, we summarize the current knowledge about cell therapy, injection of cytokines and short peptides to rescue the degenerating IVD. We further stress that most bioreactor systems simplify the real in vivo conditions providing a useful proof of concept. Limitations are that certain aspects of the immune host response and pain assessments cannot be addressed with ex vivo systems. Coccygeal animal disc models are commonly used because of their availability and similarity to human IVDs. Although in vitro loading environments are not identical to the human in vivo situation, 3D ex vivo organ culture models of large animal coccygeal and human lumbar IVDs should be seen as valid alternatives for screening and feasibility testing to augment existing small animal, large animal, and human clinical trial experiments.

The Logistic System Concept and Foreign Military Sales, U.S. Navy - Royal Norwegian Navy.

DTIC Science & Technology

1976-12-01

FMS organization and the theoretical logistical model. Areas of special concern are identified to be order processing , communications, transportation and training of individuals in the customer’s FMS organization.

The organism as ontological go-between: hybridity, boundaries and degrees of reality in its conceptual history.

PubMed

Wolfe, Charles T

2014-12-01

The organism is neither a discovery like the circulation of the blood or the glycogenic function of the liver, nor a particular biological theory like epigenesis or preformationism. It is rather a concept which plays a series of roles--sometimes overt, sometimes masked--throughout the history of biology, and frequently in very normative ways, also shifting between the biological and the social. Indeed, it has often been presented as a key-concept in life science and the 'theorization' of Life, but conversely has also been the target of influential rejections: as just an instrument of transmission for the selfish gene, but also, historiographically, as part of an outdated 'vitalism'. Indeed, the organism, perhaps because it is experientially closer to the 'body' than to the 'molecule', is often the object of quasi-affective theoretical investments presenting it as essential, sometimes even as the pivot of a science or a particular approach to nature, while other approaches reject or attack it with equal force, assimilating it to a mysterious 'vitalist' ontology of extra-causal forces, or other pseudo-scientific doctrines. This paper does not seek to adjudicate between these debates, either in terms of scientific validity or historical coherence; nor does it return to the well-studied issue of the organism-mechanism tension in biology. Recent scholarship has begun to focus on the emergence and transformation of the concept of organism, but has not emphasized so much the way in which organism is a shifting, 'go-between' concept-invoked as 'natural' by some thinkers to justify their metaphysics, but then presented as value-laden by others, over and against the natural world. The organism as go-between concept is also a hybrid, a boundary concept or an epistemic limit case, all of which partly overlap with the idea of 'nomadic concepts'. Thereby the concept of organism continues to function in different contexts--as a heuristic, an explanatory challenge, a model of order, of regulation, etc.--despite having frequently been pronounced irrelevant and reduced to molecules or genes. Yet this perpetuation is far removed from any 'metaphysics of organism', or organismic biology. Copyright © 2014 Elsevier Ltd. All rights reserved.

The Impact of Using Model of Marzano Gain Students the Ability to Configure an Integrated Conceptual Structure in Islamic Concepts

ERIC Educational Resources Information Center

Alkhateeb, Omar

2015-01-01

The study aimed that the impact of using model of Marzano gain students the ability to configure an integrated conceptual structure in Islamic concepts the Sample included studious (120) student students the first year where of college of the educational sciences study in, two branches be organized in their choice was complete random among seven…

Profile of students’ learning styles in Sorogan-Bandongan organic chemistry lecture

NASA Astrophysics Data System (ADS)

Rinaningsih; Kadarohman, A.; Firman, H.; Sutoyo

2018-05-01

Individual-based independent curriculum as one of target of national education of Indonesia in XXI century can be achieved with the implementation of Sorogan-Bandongan model. This kind of learning model highly facilitates students in understanding various concepts with their own, respective learning styles. This research aims to perceive the effectiveness of Sorogan-Bandongan in increasing the mastery of concept in various learning styles. The samples of this research are students majoring in chemistry amounted to 31 students. Using pre-test and post-test instrument, data are analyzed in descriptive-qualitative method. Based on the result of the data analysis, it is found that 16% of students have mathematical/logical learning style, 22.6% naturalist, 9.7% visual/spatial, 13% kinesthetic, 6% linguistic, 13% intrapersonal, 9.7% interpersonal, and 10% musical. After the implementation of Sorogan-Bandongan model in the Organic Chemistry lectures, improvement of classical learning outcomes as 11,07 is obtained. Six out of eight learning styles of students experienced increase in mastery of concept, where 7 students have the naturalist learning style, 4 students experienced decrease in mastery of concept while 1 student is stagnant (0); meanwhile, 2 out of 4 students that have the interpersonal learning style experienced decrease in mastery of concept.

An analysis of the concept of competence in individuals and social systems.

PubMed

Adler, P T

1982-01-01

This paper has attempted to present a unified conceptual model of positive mental health or competence from the perspective of individuals and from the perspective of social systems of varying degrees of complexity, such as families, organizations, and entire communities. It has provided a taxonomy of the elements of competence which allows the application of a common framework to the analysis of competence and to the planning and evaluation of competence building interventions at any level of social organization. Community Mental Health Centers can apply the model which has been presented in a number of different ways. At whatever level(s) the CMHCs' efforts are directed, the competence model presents a framework for analysis, intervention, and evaluation which enriches and expands upon more typical disorder-based formulations. By providing a framework which encompasses all levels of social organization, the model provides the conceptual tools for going beyond the individual and microsystem levels which have often constituted the boundaries of CMHC concern, and allows the CMHC to approach the organizational and community levels which must be encompassed by a competently comprehensive center. Application of the concept of competence to social organizations and to communities allows the CMHC to analyze and intervene at these levels. Finally, the concept of organizational competence separated into its various elements provides the CMHC with a tool for analyzing and evaluating its own environment and the competence of various aspects of its own functioning within that environment.

Using semantic data modeling techniques to organize an object-oriented database for extending the mass storage model

NASA Technical Reports Server (NTRS)

Campbell, William J.; Short, Nicholas M., Jr.; Roelofs, Larry H.; Dorfman, Erik

1991-01-01

A methodology for optimizing organization of data obtained by NASA earth and space missions is discussed. The methodology uses a concept based on semantic data modeling techniques implemented in a hierarchical storage model. The modeling is used to organize objects in mass storage devices, relational database systems, and object-oriented databases. The semantic data modeling at the metadata record level is examined, including the simulation of a knowledge base and semantic metadata storage issues. The semantic data model hierarchy and its application for efficient data storage is addressed, as is the mapping of the application structure to the mass storage.

Excellence and evidence in staffing: a data-driven model for excellence in staffing (2nd edition).

PubMed

Baggett, Margarita; Batcheller, Joyce; Blouin, Ann Scott; Behrens, Elizabeth; Bradley, Carol; Brown, Mary J; Brown, Diane Storer; Bolton, Linda Burnes; Borromeo, Annabelle R; Burtson, Paige; Caramanica, Laura; Caspers, Barbara A; Chow, Marilyn; Christopher, Mary Ann; Clarke, Sean P; Delucas, Christine; Dent, Robert L; Disser, Tony; Eliopoulos, Charlotte; Everett, Linda Q; Garcia, Amy; Glassman, Kimberly; Goodwin, Susan; Haagenson, Deb; Harper, Ellen; Harris, Kathy; Hoying, Cheryl L; Hughes-Rease, Marsha; Kelly, Lesly; Kiger, Anna J; Kobs-Abbott, Ann; Krueger, Janelle; Larson, Jackie; March, Connie; Martin, Deborah Maust; Mazyck, Donna; Meenan, Penny; McGaffigan, Patricia; Myers, Karen K; Nell, Kate; Newcomer, Britta; Cathy, Rick; O'Rourke, Maria; Rosa, Billy; Rose, Robert; Rudisill, Pamela; Sanford, Kathy; Simpson, Roy L; Snowden, Tami; Strickland, Bob; Strohecker, Sharon; Weems, Roger B; Welton, John; Weston, Marla; Valentine, Nancy M; Vento, Laura; Yendro, Susan

2014-01-01

The Patient Protection and Affordable Care Act (PPACA, 2010) and the Institute of Medicine's (IOM, 2011) Future of Nursing report have prompted changes in the U.S. health care system. This has also stimulated a new direction of thinking for the profession of nursing. New payment and priority structures, where value is placed ahead of volume in care, will start to define our health system in new and unknown ways for years. One thing we all know for sure: we cannot afford the same inefficient models and systems of care of yesterday any longer. The Data-Driven Model for Excellence in Staffing was created as the organizing framework to lead the development of best practices for nurse staffing across the continuum through research and innovation. Regardless of the setting, nurses must integrate multiple concepts with the value of professional nursing to create new care and staffing models. Traditional models demonstrate that nurses are a commodity. If the profession is to make any significant changes in nurse staffing, it is through the articulation of the value of our professional practice within the overall health care environment. This position paper is organized around the concepts from the Data-Driven Model for Excellence in Staffing. The main concepts are: Core Concept 1: Users and Patients of Health Care, Core Concept 2: Providers of Health Care, Core Concept 3: Environment of Care, Core Concept 4: Delivery of Care, Core Concept 5: Quality, Safety, and Outcomes of Care. This position paper provides a comprehensive view of those concepts and components, why those concepts and components are important in this new era of nurse staffing, and a 3-year challenge that will push the nursing profession forward in all settings across the care continuum. There are decades of research supporting various changes to nurse staffing. Yet little has been done to move that research into practice and operations. While the primary goal of this position paper is to generate research and innovative thinking about nurse staffing across all health care settings, a second goal is to stimulate additional publications. This includes a goal of at least 20 articles in Nursing Economic$ on best practices in staffing and care models from across the continuum over the next 3 years.

Complex Adaptive Systems as Metaphors for Organizational Management

ERIC Educational Resources Information Center

Palmberg, Klara

2009-01-01

Purpose: The purpose of this paper is to explore the concept of complex adaptive systems (CAS) from the perspective of managing organizations, to describe and explore the management principles in a case study of an organization with unconventional ways of management and to present a tentative model for managing organizations as CAS--system…

An Empirical Study of Relationships between Student Self-Concept and Science Achievement in Hong Kong

ERIC Educational Resources Information Center

Wang, Jianjun; Oliver, Steve; Garcia, Augustine

2004-01-01

Positive self-concept and good understanding of science are important indicators of scientific literacy endorsed by professional organizations. The existing research literature suggests that these two indicators are reciprocally related and mutually reinforcing. Generalization of the reciprocal model demands empirical studies in different…

Organization of functional interaction of corporate information systems

NASA Astrophysics Data System (ADS)

Safronov, V. V.; Barabanov, V. F.; Podvalniy, S. L.; Nuzhnyy, A. M.

2018-03-01

In this article the methods of specialized software systems integration are analyzed and the concept of seamless integration of production decisions is offered. In view of this concept developed structural and functional schemes of the specialized software are shown. The proposed schemes and models are improved for a machine-building enterprise.

Organ Culture Bioreactors – Platforms to Study Human Intervertebral Disc Degeneration and Regenerative Therapy

PubMed Central

Gantenbein, Benjamin; Illien-Jünger, Svenja; Chan, Samantha CW; Walser, Jochen; Haglund, Lisbet; Ferguson, Stephen J; Iatridis, James C; Grad, Sibylle

2015-01-01

In recent decades the application of bioreactors has revolutionized the concept of culturing tissues and organs that require mechanical loading. In intervertebral disc (IVD) research, collaborative efforts of biomedical engineering, biology and mechatronics have led to the innovation of new loading devices that can maintain viable IVD organ explants from large animals and human cadavers in precisely defined nutritional and mechanical environments over extended culture periods. Particularly in spine and IVD research, these organ culture models offer appealing alternatives, as large bipedal animal models with naturally occurring IVD degeneration and a genetic background similar to the human condition do not exist. Latest research has demonstrated important concepts including the potential of homing of mesenchymal stem cells to nutritionally or mechanically stressed IVDs, and the regenerative potential of “smart” biomaterials for nucleus pulposus or annulus fibrosus repair. In this review, we summarize the current knowledge about cell therapy, injection of cytokines and short peptides to rescue the degenerating IVD. We further stress that most bioreactor systems simplify the real in vivo conditions providing a useful proof of concept. Limitations are that certain aspects of the immune host response and pain assessments cannot be addressed with ex vivo systems. Coccygeal animal disc models are commonly used because of their availability and similarity to human IVDs. Although in vitro loading environments are not identical to the human in vivo situation, 3D ex vivo organ culture models of large animal coccygeal and human lumbar IVDs should be seen as valid alternatives for screening and feasibility testing to augment existing small animal, large animal, and human clinical trial experiments. PMID:25764196

Analysis of Business Connections Utilizing Theory of Topology of Random Graphs

NASA Astrophysics Data System (ADS)

Trelewicz, Jennifer Q.; Volovich, Igor V.

2006-03-01

A business ecosystem is a system that describes interactions between organizations. In this paper, we build a theoretical framework that defines a model which can be used to analyze the business ecosystem. The basic concepts within the framework are organizations, business connections, and market, that are all defined in the paper. Many researchers analyze the performance and structure of business using the workflow of the business. Our work in business connections answers a different set of questions, concerning the monetary value in the business ecosystem, rather than the task-interaction view that is provided by workflow analysis. We apply methods for analysis of the topology of complex networks, characterized by the concepts of small path length, clustering, and scale-free degree distributions. To model the dynamics of the business ecosystem we analyze the notion of the state of an organization at a given instant of time. We point out that the notion of state in this case is fundamentally different from the concept of state of the system which is used in classical or quantum physics. To describe the state of the organization at a given time one has to know the probability of payments to contracts which in fact depend on the future behavior of the agents on the market. Therefore methods of p-adic analysis are appropriate to explore such a behavior. Microeconomic and macroeconomic factors are indivisible and moreover the actual state of the organization depends on the future. In this framework some simple models are analyzed in detail. Company strategy can be influenced by analysis of models, which can provide a probabilistic understanding of the market, giving degrees of predictability.

An organizing model for recent cognitive science work on the self.

PubMed

Pageler, Ben

2016-10-01

An organizing model of 'the self' emerges from applying various kinds of brain injury to recent cognitive science and philosophical work on 'the self'. This model unifies various contents and mechanisms central to current notions of the self. The article then highlights several criteria and aspects of this notion of self. Qualities of the right type and level of psychological significance delineate 'the self' as an organizing concept useful for recent philosophical work and cognitive science research. Copyright © 2016 Elsevier Inc. All rights reserved.

Factor Structure of the Primary Scales of the Inventory of Personality Organization in a Nonclinical Sample Using Exploratory Structural Equation Modeling

ERIC Educational Resources Information Center

Ellison, William D.; Levy, Kenneth N.

2012-01-01

Using exploratory structural equation modeling and multiple regression, we examined the factor structure and criterion relations of the primary scales of the Inventory of Personality Organization (IPO; Kernberg & Clarkin, 1995) in a nonclinical sample. Participants (N = 1,260) completed the IPO and measures of self-concept clarity, defenses,…

[Nursing and marketing: an introduction to the subject].

PubMed

de Moura, Gisela Maria Schebella Souto

2003-08-01

The administration of health care services is becoming more and more professional. New models and strategies used by service companies, in other areas, are being introduced in these organizations. Through this importation process of models, marketing concepts and tools have been incorporated. The objective of this theoretical essay is offering the nurses an introductory view about marketing. In order to reach this objective, the text was organized into sections that approach its history and basic concepts, social marketing, a few subjects under discussion currently and studies carried out in the marketing area, which involve nursing and health care services. In this way, it is expected to contribute to the professional improvement of nursing.

Abstracting event-based control models for high autonomy systems

NASA Technical Reports Server (NTRS)

Luh, Cheng-Jye; Zeigler, Bernard P.

1993-01-01

A high autonomy system needs many models on which to base control, management, design, and other interventions. These models differ in level of abstraction and in formalism. Concepts and tools are needed to organize the models into a coherent whole. The paper deals with the abstraction processes for systematic derivation of related models for use in event-based control. The multifaceted modeling methodology is briefly reviewed. The morphism concepts needed for application to model abstraction are described. A theory for supporting the construction of DEVS models needed for event-based control is then presented. An implemented morphism on the basis of this theory is also described.

Introduction to Software Product Line Adoption

DTIC Science & Technology

2005-09-01

plans • improvement suggestions • risks and mitigation strategies • progress reports • risks and mitigation strategies • adoption plan • funding ... model • organization chart • product line concept of operations (CONOPS) • marketing plan • product proposals • acquisition strategy • organization risk

Applying Organ Clearance Concepts in a Clinical Setting

PubMed Central

2008-01-01

Objective To teach doctor of pharmacy (PharmD) students how to apply organ clearance concepts in a clinical setting in order to optimize dose management, select the right drug product, and promote better patient-centered care practices. Design A student-focused 5-hour topic entitled "Organ Clearance Concepts: Modeling and Clinical Applications" was developed and delivered to second-year PharmD students. Active-learning techniques, such as reading assignments and thought-provoking questions, and collaborative learning techniques, such as small groups, were used. Student learning was assessed using application cards and a minute paper. Assessment Overall student responses to topic presentation were overwhelmingly positive. The teaching strategies here discussed allowed students to play an active role in their own learning process and provided the necessary connection to keep them motivated, as mentioned in the application cards and minute paper assessments. Students scored an average of 88% on the examination given at the end of the course. Conclusion By incorporating active-learning and collaborative-learning techniques in presenting material on organ clearance concept, students gained a more thorough knowledge of dose management and drug-drug interactions than if the concepts had been presented using a traditional lecture format. This knowledge will help students in solving critical patient situations in a real-world context. PMID:19214275

Concept-oriented indexing of video databases: toward semantic sensitive retrieval and browsing.

PubMed

Fan, Jianping; Luo, Hangzai; Elmagarmid, Ahmed K

2004-07-01

Digital video now plays an important role in medical education, health care, telemedicine and other medical applications. Several content-based video retrieval (CBVR) systems have been proposed in the past, but they still suffer from the following challenging problems: semantic gap, semantic video concept modeling, semantic video classification, and concept-oriented video database indexing and access. In this paper, we propose a novel framework to make some advances toward the final goal to solve these problems. Specifically, the framework includes: 1) a semantic-sensitive video content representation framework by using principal video shots to enhance the quality of features; 2) semantic video concept interpretation by using flexible mixture model to bridge the semantic gap; 3) a novel semantic video-classifier training framework by integrating feature selection, parameter estimation, and model selection seamlessly in a single algorithm; and 4) a concept-oriented video database organization technique through a certain domain-dependent concept hierarchy to enable semantic-sensitive video retrieval and browsing.

Organizational Learning and the Learning Organization: Reviewing Evolution for Prospecting the Future

ERIC Educational Resources Information Center

Rebelo, Teresa Manuela; Gomes, Adelino Duarte

2008-01-01

Purpose: The purpose of this article is to analyse the evolution of the concepts of organizational learning and the learning organization and propose guidelines for the future. Design/methodology/approach: The evolution of organizational learning and the learning organization is analysed in the light of the three-stage model of the evolution of…

A Model for Infusing Energy Concepts into Vocational Education Programs. Solar Energy Curriculum Guide.

ERIC Educational Resources Information Center

Delta Vocational Technical School, Marked Tree, AR.

This solar energy curriculum guide is designed to assist teachers in infusing energy concepts into vocational education programs. It consists of 31 competency-based instructional units organized into 10 sections. Covered in the sections are the following topics: related instructions (history and development; human relations; general safety;…

Malevolent Creativity in Terrorist Organizations

ERIC Educational Resources Information Center

Gill, Paul; Horgan, John; Hunter, Samuel T.; Cushenbery, Lily D.

2013-01-01

Terrorist organizations are both imitative and innovative in character. While the drivers of imitation have been extensively modeled using concepts such as contagion and diffusion, creativity and innovation remain relatively underdeveloped ideas in the context of terrorist behavior. This article seeks to redress this deficiency by presenting a…

The History and Generality of AQUATOX, a Robust Mechanistic Model

EPA Science Inventory

In 1987, the U.S. Environmental Protection Agency sponsored a workshop in Baltimore on modeling the fate and effects of toxic organics. The specifications for the AQUATOX model came out of this workshop, and the first paper on the modeling concept was published soon after. Since ...

Students' Mental Models of Atomic Spectra

ERIC Educational Resources Information Center

Körhasan, Nilüfer Didis; Wang, Lu

2016-01-01

Mental modeling, which is a theory about knowledge organization, has been recently studied by science educators to examine students' understanding of scientific concepts. This qualitative study investigates undergraduate students' mental models of atomic spectra. Nine second-year physics students, who have already taken the basic chemistry and…

Personality from a cognitive-biological perspective

NASA Astrophysics Data System (ADS)

Neuman, Yair

2014-12-01

The term "personality" is used to describe a distinctive and relatively stable set of mental traits that aim to explain the organism's behavior. The concept of personality that emerged in human psychology has been also applied to the study of non-human organisms from birds to horses. In this paper, I critically review the concept of personality from an interdisciplinary perspective, and point to some ideas that may be used for developing a cognitive-biological theory of personality. Integrating theories and research findings from various fields such as cognitive ethnology, clinical psychology, and neuroscience, I argue that the common denominator of various personality theories are neural systems of threat/trust management and their emotional, cognitive, and behavioral dimensions. In this context, personality may be also conceived as a meta-heuristics both human and non-human organisms apply to model and predict the behavior of others. The paper concludes by suggesting a minimal computational model of personality that may guide future research.

The Role of Social Work Leadership: Mount Sinai Care, the Accountable Care Organization, and Population Health Management.

PubMed

Xenakis, Nancy

2015-10-01

In July 2012, The Mount Sinai Medical Center was selected by the Centers for Medicare and Medicaid to join the first cohort of Accountable Care Organizations (ACOs) in this country under its Medicare Shared Savings Program. A critical component of an ACO is care coordination of patients, which is a complex concept, intertwined with other concepts related to quality, delivery and organization of health care. This article provides an overview of the development, structure and functionality of Mount Sinai Care, the ACO of The Mount Sinai Health System, and how it was the beginning of its work in population health management. It describes the important role of social work leadership in the development and operation of its care coordination model. The model's successes and challenges and recommendations for future development of care coordination and population health management are outlined.

Role of conceptual models in a physical therapy curriculum: application of an integrated model of theory, research, and clinical practice.

PubMed

Darrah, Johanna; Loomis, Joan; Manns, Patricia; Norton, Barbara; May, Laura

2006-11-01

The Department of Physical Therapy, University of Alberta, Edmonton, Alberta, Canada, recently implemented a Master of Physical Therapy (MPT) entry-level degree program. As part of the curriculum design, two models were developed, a Model of Best Practice and the Clinical Decision-Making Model. Both models incorporate four key concepts of the new curriculum: 1) the concept that theory, research, and clinical practice are interdependent and inform each other; 2) the importance of client-centered practice; 3) the terminology and philosophical framework of the World Health Organization's International Classification of Functioning, Disability, and Health; and 4) the importance of evidence-based practice. In this article the general purposes of models for learning are described; the two models developed for the MPT program are described; and examples of their use with curriculum design and teaching are provided. Our experiences with both the development and use of models of practice have been positive. The models have provided both faculty and students with a simple, systematic structured framework to organize teaching and learning in the MPT program.

[Discussion on agricultural product quality and safety problem from ecological view].

PubMed

Xiao, Ming; Dong, Nan; Lyu, Xin

2015-08-01

There are many different perspectives about the sustainable agriculture, which had been proposed since the last three decades in the world. While China's ecologists and agronomists proposed a similar concept named 'ecological agriculture'. Although ecological agriculture in China has achieved substantial progress, including theory, models and supporting technologies nearly several decades of practice and development, its application guidance still is not yet clear. The organic agriculture model proposed by European Union is popular, but it is limited in the beneficiary groups and the social and ecological responsibility. In this context, the article based on an ecological point of view, analyzed the shortcomings of ecological imbalance caused by a single mode of agricultural production and the negative impact on the quality of agricultural products, and discussed the core values of ecological agriculture. On this basis, we put forward the concept of sustainable security of agricultural products. Based on this concept, an agricultural platform was established under the healthy ecosysphere environment, and from this agricultural platform, agricultural products could be safely and sustainably obtained. Around the central value of the concept, we designed the agricultural sustainable and security production model. Finally, we compared the responsibility, benefiting groups, agronomic practices selection and other aspects of sustainable agriculture with organic agriculture, and proved the advancement of sustainable agricultural model in agricultural production quality and safety.

Springtails in the Classroom: Collembola as Model Organisms for Inquiry-based Laboratories.

ERIC Educational Resources Information Center

Moore, John C.; Tripp, Bradley B.; Simpson, Rod T.; Coleman, David C.

2000-01-01

Advocates the use of springtails (Collembola) in the K-12 classroom as a model invertebrate that can easily be reared and manipulated to demonstrate key concepts in biology. Describes experimental procedures using springtails. (SAH)

[Longevity control in fungi and other organisms. The conception of scales].

PubMed

Mazheĭka, I S; Kudriavtseva, O A; Kamzolkina, O V

2011-01-01

The review deals mainly with gerontological processes that occur on the cellular-colonial level of organization in fungi and cellular-tissular level in other organisms. Aging and anti-aging mechanisms operating on these levels of organization can be considered as common ones for all living things. Fungi, as an object with tissular-like organization of thallus, afford a broad spectrum of possibilities as to solving the tasks of general gerontological import. Three basic (chronological, replicative, and cell-suicidal) and several auxiliary mechanisms of aging are singled out, the classification is given of stochastic aging factors accumulating in cells. It is shown that in complex multi-cellular organisms, aging and anti-aging mechanisms operate on the level of interactions between tissues, though in the base of their actions lie the aforesaid conservative basic mechanisms. Preliminary generalized conception of aging--the conception of scales--is put forward that is founded on the model of balanced and non-balanced counteractions between stressful impacts and various mechanisms of aging and anti-aging with different extent of genetic preprogramming. The importance is reaffirmed of mycological gerontology contribution to broadening of inferences on aging nature.

A systems concept of the vestibular organs

NASA Technical Reports Server (NTRS)

Mayne, R.

1974-01-01

A comprehensive model of vestibular organ function is presented. The model is based on an analogy with the inertial guidance systems used in navigation. Three distinct operations are investigated: angular motion sensing, linear motion sensing, and computation. These operations correspond to the semicircular canals, the otoliths, and central processing respectively. It is especially important for both an inertial guidance system and the vestibular organs to distinguish between attitude with respect to the vertical on the one hand, and linear velocity and displacement on the other. The model is applied to various experimental situations and found to be corroborated by them.

Utility Computing: Reality and Beyond

NASA Astrophysics Data System (ADS)

Ivanov, Ivan I.

Utility Computing is not a new concept. It involves organizing and providing a wide range of computing-related services as public utilities. Much like water, gas, electricity and telecommunications, the concept of computing as public utility was announced in 1955. Utility Computing remained a concept for near 50 years. Now some models and forms of Utility Computing are emerging such as storage and server virtualization, grid computing, and automated provisioning. Recent trends in Utility Computing as a complex technology involve business procedures that could profoundly transform the nature of companies' IT services, organizational IT strategies and technology infrastructure, and business models. In the ultimate Utility Computing models, organizations will be able to acquire as much IT services as they need, whenever and wherever they need them. Based on networked businesses and new secure online applications, Utility Computing would facilitate "agility-integration" of IT resources and services within and between virtual companies. With the application of Utility Computing there could be concealment of the complexity of IT, reduction of operational expenses, and converting of IT costs to variable `on-demand' services. How far should technology, business and society go to adopt Utility Computing forms, modes and models?

Entrepreneurial organizations: the driving force for improving quality in the healthcare industry.

PubMed

Borkowski, Nancy; Gordon, Jean

2006-01-01

Using DiMaggio and Powell's concept of institutional isomorphism, the authors explain why healthcare lags behind other industries in innovating new production functions that address quality. Healthcare finns can "learn" to be entrepreneurial organizations within Stevenson's 'entrepreneurial versus administrative behavior' framework and Covin and Slevin's model of an entrepreneurial organization's required culture and behavioral support structure.

Security giving in surrogacy motherhood process as a caring model for commissioning mothers: A theory synthesis.

PubMed

Zandi, Mitra; Vanaki, Zohreh; Shiva, Marziyeh; Mohammadi, Eesa; Bagheri-Lankarani, Narges

2016-07-01

Despite the increasing use of surrogacy, there are no caring theories/models that serve as the basis for nursing care to surrogacy commissioning mothers. This study has designed a model for caring of surrogacy commissioning mothers in 2013. The theory synthesis of Walker and Avant's strategies of theory construction (2011) was used to design a caring model/theory. The theory synthesis includes three stages: (i) selection of focal concept (the concept of "security giving in motherhood" was selected); (ii) review of studies in order to identify factors related to focal concept relevant studies (42 articles and 13 books) were reviewed, statements and concepts related to focal concept were then extracted and classified, and their relations were specified; and (iii) organization of concepts and statements within a relevant general and effective manifestation of the phenomenon under study which led to developing of a model. In this caring model/theory, entitled "security giving in surrogacy motherhood", nurses roles were conceptualized within the conceptual framework that includes three main roles: (i) coordination; (ii) participation; and (iii) security giving (physical, emotional, and legal support; empowerment; presence; relationship management between both parties and advocacy). Training surrogacy specialist nurses and establishment of surrogacy care centers are important factors for implementation of the model. This model could help to provided better caring for surrogacy clients, especially for commissioning mothers. © 2016 Japan Academy of Nursing Science.

The Learning Organization Model across Vocational and Academic Teacher Groups

ERIC Educational Resources Information Center

Park, Joo Ho; Rojewski, Jay W.

2006-01-01

Multiple-group confirmatory factor analysis was used to investigate factorial invariance between vocational and academic teacher groups on a measure of the learning organization concept. Participants were 488 full-time teachers of public trade industry-technical and business schools located within Seoul, South Korea. Statistically significant…

The Organization as Client: Broadening the Concept of Employee Assistance Programs.

ERIC Educational Resources Information Center

Googins, Bradley; Davidson, Bruce N.

1993-01-01

Notes that many employee assistance programs (EAPs) are broadening their function to address rapidly changing human and social issues of environments in which they operate, refocusing practice to include organization as the client. Discusses traditional EAP practice, evolution of EAPs, changes confronting corporations, and alternative model in…

ORCA Project: Research on high-performance parallel computer programming environments. Final report, 1 Apr-31 Mar 90

DOE Office of Scientific and Technical Information (OSTI.GOV)

Snyder, L.; Notkin, D.; Adams, L.

1990-03-31

This task relates to research on programming massively parallel computers. Previous work on the Ensamble concept of programming was extended and investigation into nonshared memory models of parallel computation was undertaken. Previous work on the Ensamble concept defined a set of programming abstractions and was used to organize the programming task into three distinct levels; Composition of machine instruction, composition of processes, and composition of phases. It was applied to shared memory models of computations. During the present research period, these concepts were extended to nonshared memory models. During the present research period, one Ph D. thesis was completed, onemore » book chapter, and six conference proceedings were published.« less

Psychodynamic therapy from the perspective of self-organization. a concept of change and a methodological approach for empirical examination.

PubMed

Gumz, Antje; Geyer, Michael; Brähler, Elmar

2014-01-01

Observations from therapeutic practice and a series of empirical findings, for example, those on discontinuous change in psychotherapeutic processes, suggest modelling the therapeutic process as a self-organizing system with stable and critical instable phases and abrupt transitions. Here, a concept of psychotherapeutic change is presented that applies self-organization theory to psychodynamic principles. The authors explain the observations and considerations that form the basis of the concept and present some connections with existing findings and concepts. On the basis of this model, they generated two hypotheses regarding the co-occurrence of instability and discontinuous change and the degree of synchrony between the therapist and patient. A study design to test these hypotheses was developed and applied to a single case (psychodynamic therapy). After each session, patient and therapist rated their interaction. A measure of instability was calculated across the resulting time series. Sequences of destabilization were observed. On the basis of points of extreme instability, the process was divided into phases. Local instability maxima were accompanied by significant discontinuous change. Destabilization was highly synchronous in therapist and patient ratings. The authors discussed the concept and the methodological procedure. The approach enables the operationalization of crises and to empirically assess the significance of critical phases and developments within the therapeutic relationship. We present a concept of change that applies self-organization theory to psychodynamic therapy. We empirically tested the hypotheses formulated in the concept based on an extract of 125 long-term psychodynamic therapy sessions. We continuously monitored the therapeutic interaction and calculated a measure of the instability of the assessments. We identified several sequences of stable and unstable episodes. Episodes of high instability were accompanied by discontinuous change. On the basis of these episodes of high instability, we divided the process into four phases. Mean values of variables differed across these phases. Destabilization proved to be highly synchronous in therapist and patient ratings. The approach allows to empirically assess critical phases and developments within the therapeutic relationship. Copyright © 2013 John Wiley & Sons, Ltd.

The Synthesis Map Is a Multidimensional Educational Tool That Provides Insight into Students’ Mental Models and Promotes Students’ Synthetic Knowledge Generation

PubMed Central

Ortega, Ryan A.; Brame, Cynthia J.

2015-01-01

Concept mapping was developed as a method of displaying and organizing hierarchical knowledge structures. Using the new, multidimensional presentation software Prezi, we have developed a new teaching technique designed to engage higher-level skills in the cognitive domain. This tool, synthesis mapping, is a natural evolution of concept mapping, which utilizes embedding to layer information within concepts. Prezi’s zooming user interface lets the author of the presentation use both depth as well as distance to show connections between data, ideas, and concepts. Students in the class Biology of Cancer created synthesis maps to illustrate their knowledge of tumorigenesis. Students used multiple organizational schemes to build their maps. We present an analysis of student work, placing special emphasis on organization within student maps and how the organization of knowledge structures in student maps can reveal strengths and weaknesses in student understanding or instruction. We also provide a discussion of best practices for instructors who would like to implement synthesis mapping in their classrooms. PMID:25917385

An Universal and Easy-to-Use Model for the Pressure of Arbitrary-Shape 3D Multifunctional Integumentary Cardiac Membranes.

PubMed

Su, Yewang; Liu, Zhuangjian; Xu, Lizhi

2016-04-20

Recently developed concepts for 3D, organ-mounted electronics for cardiac applications require a universal and easy-to-use mechanical model to calculate the average pressure associated with operation of the device, which is crucial for evaluation of design efficacy and optimization. This work proposes a simple, accurate, easy-to-use, and universal model to quantify the average pressure for arbitrary-shape organs. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Biological Model Development as an Opportunity to Provide Content Auditing for the Foundational Model of Anatomy Ontology.

PubMed

Wang, Lucy L; Grunblatt, Eli; Jung, Hyunggu; Kalet, Ira J; Whipple, Mark E

2015-01-01

Constructing a biological model using an established ontology provides a unique opportunity to perform content auditing on the ontology. We built a Markov chain model to study tumor metastasis in the regional lymphatics of patients with head and neck squamous cell carcinoma (HNSCC). The model attempts to determine regions with high likelihood for metastasis, which guides surgeons and radiation oncologists in selecting the boundaries of treatment. To achieve consistent anatomical relationships, the nodes in our model are populated using lymphatic objects extracted from the Foundational Model of Anatomy (FMA) ontology. During this process, we discovered several classes of inconsistencies in the lymphatic representations within the FMA. We were able to use this model building opportunity to audit the entities and connections in this region of interest (ROI). We found five subclasses of errors that are computationally detectable and resolvable, one subclass of errors that is computationally detectable but unresolvable, requiring the assistance of a content expert, and also errors of content, which cannot be detected through computational means. Mathematical descriptions of detectable errors along with expert review were used to discover inconsistencies and suggest concepts for addition and removal. Out of 106 organ and organ parts in the ROI, 8 unique entities were affected, leading to the suggestion of 30 concepts for addition and 4 for removal. Out of 27 lymphatic chain instances, 23 were found to have errors, with a total of 32 concepts suggested for addition and 15 concepts for removal. These content corrections are necessary for the accurate functioning of the FMA and provide benefits for future research and educational uses.

Biological Model Development as an Opportunity to Provide Content Auditing for the Foundational Model of Anatomy Ontology

PubMed Central

Wang, Lucy L.; Grunblatt, Eli; Jung, Hyunggu; Kalet, Ira J.; Whipple, Mark E.

2015-01-01

Constructing a biological model using an established ontology provides a unique opportunity to perform content auditing on the ontology. We built a Markov chain model to study tumor metastasis in the regional lymphatics of patients with head and neck squamous cell carcinoma (HNSCC). The model attempts to determine regions with high likelihood for metastasis, which guides surgeons and radiation oncologists in selecting the boundaries of treatment. To achieve consistent anatomical relationships, the nodes in our model are populated using lymphatic objects extracted from the Foundational Model of Anatomy (FMA) ontology. During this process, we discovered several classes of inconsistencies in the lymphatic representations within the FMA. We were able to use this model building opportunity to audit the entities and connections in this region of interest (ROI). We found five subclasses of errors that are computationally detectable and resolvable, one subclass of errors that is computationally detectable but unresolvable, requiring the assistance of a content expert, and also errors of content, which cannot be detected through computational means. Mathematical descriptions of detectable errors along with expert review were used to discover inconsistencies and suggest concepts for addition and removal. Out of 106 organ and organ parts in the ROI, 8 unique entities were affected, leading to the suggestion of 30 concepts for addition and 4 for removal. Out of 27 lymphatic chain instances, 23 were found to have errors, with a total of 32 concepts suggested for addition and 15 concepts for removal. These content corrections are necessary for the accurate functioning of the FMA and provide benefits for future research and educational uses. PMID:26958311

[Epidemiological intelligence as a model of organization in health].

PubMed

Rodrigues-Júnior, Antonio Luiz

2012-03-01

The concept of epidemiological intelligence, as a construction of information societies, goes beyond monitoring a list of diseases and the ability to elicit rapid responses. The concept should consider the complexity of the definition of epidemiology in the identification of this object of study without being limited to a set of actions in a single government sector. The activities of epidemiological intelligence include risk assessment, strategies for prevention and protection, subsystems of information, crisis management rooms, geographical analysis, etc. This concept contributes to the understanding of policies in health, in multisectorial and geopolitical dimensions, as regards the organization of services around public health emergencies, primary healthcare, as well as disasters. The activities of epidemiological intelligence should not be restricted to scientific research, but the researchers must beware of threats to public health. Lalonde's model enabled consideration of epidemiological intelligence as a way to restructure policies and share resources by creating communities of intelligence, whose purpose is primarily to deal with public health emergencies and disasters.

[Volunteer satisfaction: Internal structure and relationship with permanence in organizations].

PubMed

Vecina Jiménez, M L; Chacón Fuertes, Fernando; Sueiro Abad, Manuel J

2009-02-01

Volunteer satisfaction: Internal structure and relationship with permanence in organizations. The concept of satisfaction is considered theoretically relevant in practically all the studies that have investigated the factors that influence the permanence of volunteer participation in organizations. However, the practical results are not conclusive, perhaps due to the wide range of ways in which the concept is understood and measured. The object of this study is: to analyse the internal structure of satisfaction and to verify its relationship with volunteer duration in organizations. The results of the factor analysis yield a three-factor structure: Satisfaction with the management of the organization, Satisfaction with the tasks, Satisfaction of motivations. The three factors allow us to differentiate between individuals who remain in the organization for a period of 12 consecutive months, and those who leave earlier. The results of structural equation model analysis show that the relationship between satisfaction and the length of time that volunteers stay with the organization is affected by the intention to remain.

Factor analytical study of the short version of the World Health Organization Quality of Life Instrument.

PubMed

Ohaeri, Jude U; Olusina, Adewunmi K; Al-Abassi, Abdul-Hamid M

2004-01-01

The domains of the 26-item World Health Organization Quality of Life Instrument (WHOQOL-Bref) contain heterogeneous items and do not encompass the logical constructs of subjective quality of life (QOL). We compared the WHO 4-domain and 6-domain models of the WHOQOL-Bref with the 8-domain model that we obtained from factor analysis (FA). Data from 118 recently recovered Nigerian psychotic patients were used in confirmatory factor analysis (CFA) to assess goodness of fit and clarity of concept. Our FA model had superior goodness of fit for CFA and provided clarity of concept. Analysis of the WHOQOL-Bref should consider the domains from FA and include 'overall QOL' as an item and dependent variable. Subjective QOL is an aggregate of the following constructs: satisfaction with life circumstances; fulfillment of needs, and opportunity for experience in the milieu.

A Holoinformational Model of the Physical Observer

NASA Astrophysics Data System (ADS)

di Biase, Francisco

2013-09-01

The author proposes a holoinformational view of the observer based, on the holonomic theory of brain/mind function and quantum brain dynamics developed by Karl Pribram, Sir John Eccles, R.L. Amoroso, Hameroff, Jibu and Yasue, and in the quantumholographic and holomovement theory of David Bohm. This conceptual framework is integrated with nonlocal information properties of the Quantum Field Theory of Umesawa, with the concept of negentropy, order, and organization developed by Shannon, Wiener, Szilard and Brillouin, and to the theories of self-organization and complexity of Prigogine, Atlan, Jantsch and Kauffman. Wheeler's "it from bit" concept of a participatory universe, and the developments of the physics of information made by Zureck and others with the concepts of statistical entropy and algorithmic entropy, related to the number of bits being processed in the mind of the observer are also considered. This new synthesis gives a self-organizing quantum nonlocal informational basis for a new model of awareness in a participatory universe. In this synthesis, awareness is conceived as meaningful quantum nonlocal information interconnecting the brain and the cosmos, by a holoinformational unified field (integrating nonlocal holistic (quantum) and local (Newtonian). We propose that the cosmology of the physical observer is this unified nonlocal quantum-holographic cosmos manifesting itself through awareness, interconnected in a participatory holistic and indivisible way the human mind-brain to all levels of the self-organizing holographic anthropic multiverse.

The Synthesis Map Is a Multidimensional Educational Tool That Provides Insight into Students' Mental Models and Promotes Students' Synthetic Knowledge Generation

ERIC Educational Resources Information Center

Ortega, Ryan A.; Brame, Cynthia J.

2015-01-01

Concept mapping was developed as a method of displaying and organizing hierarchical knowledge structures. Using the new, multidimensional presentation software Prezi, we have developed a new teaching technique designed to engage higher-level skills in the cognitive domain. This tool, synthesis mapping, is a natural evolution of concept mapping,…

Proposed Core Competencies and Empirical Validation Procedure in Competency Modeling: Confirmation and Classification.

PubMed

Baczyńska, Anna K; Rowiński, Tomasz; Cybis, Natalia

2016-01-01

Competency models provide insight into key skills which are common to many positions in an organization. Moreover, there is a range of competencies that is used by many companies. Researchers have developed core competency terminology to underline their cross-organizational value. The article presents a theoretical model of core competencies consisting of two main higher-order competencies called performance and entrepreneurship. Each of them consists of three elements: the performance competency includes cooperation, organization of work and goal orientation, while entrepreneurship includes innovativeness, calculated risk-taking and pro-activeness. However, there is lack of empirical validation of competency concepts in organizations and this would seem crucial for obtaining reliable results from organizational research. We propose a two-step empirical validation procedure: (1) confirmation factor analysis, and (2) classification of employees. The sample consisted of 636 respondents (M = 44.5; SD = 15.1). Participants were administered a questionnaire developed for the study purpose. The reliability, measured by Cronbach's alpha, ranged from 0.60 to 0.83 for six scales. Next, we tested the model using a confirmatory factor analysis. The two separate, single models of performance and entrepreneurial orientations fit quite well to the data, while a complex model based on the two single concepts needs further research. In the classification of employees based on the two higher order competencies we obtained four main groups of employees. Their profiles relate to those found in the literature, including so-called niche finders and top performers. Some proposal for organizations is discussed.

Integrating nursing diagnostic concepts into the medical entities dictionary using the ISO Reference Terminology Model for Nursing Diagnosis.

PubMed

Hwang, Jee-In; Cimino, James J; Bakken, Suzanne

2003-01-01

The purposes of the study were (1) to evaluate the usefulness of the International Standards Organization (ISO) Reference Terminology Model for Nursing Diagnoses as a terminology model for defining nursing diagnostic concepts in the Medical Entities Dictionary (MED) and (2) to create the additional hierarchical structures required for integration of nursing diagnostic concepts into the MED. The authors dissected nursing diagnostic terms from two source terminologies (Home Health Care Classification and the Omaha System) into the semantic categories of the ISO model. Consistent with the ISO model, they selected Focus and Judgment as required semantic categories for creating intensional definitions of nursing diagnostic concepts in the MED. Because the MED does not include Focus and Judgment hierarchies, the authors developed them to define the nursing diagnostic concepts. The ISO model was sufficient for dissecting the source terminologies into atomic terms. The authors identified 162 unique focus concepts from the 266 nursing diagnosis terms for inclusion in the Focus hierarchy. For the Judgment hierarchy, the authors precoordinated Judgment and Potentiality instead of using Potentiality as a qualifier of Judgment as in the ISO model. Impairment and Alteration were the most frequently occurring judgments. Nursing care represents a large proportion of health care activities; thus, it is vital that terms used by nurses are integrated into concept-oriented terminologies that provide broad coverage for the domain of health care. This study supports the utility of the ISO Reference Terminology Model for Nursing Diagnoses as a facilitator for the integration process.

Integrating Nursing Diagnostic Concepts into the Medical Entities Dictionary Using the ISO Reference Terminology Model for Nursing Diagnosis

PubMed Central

Hwang, Jee-In; Cimino, James J.; Bakken, Suzanne

2003-01-01

Objective: The purposes of the study were (1) to evaluate the usefulness of the International Standards Organization (ISO) Reference Terminology Model for Nursing Diagnoses as a terminology model for defining nursing diagnostic concepts in the Medical Entities Dictionary (MED) and (2) to create the additional hierarchical structures required for integration of nursing diagnostic concepts into the MED. Design and Measurements: The authors dissected nursing diagnostic terms from two source terminologies (Home Health Care Classification and the Omaha System) into the semantic categories of the ISO model. Consistent with the ISO model, they selected Focus and Judgment as required semantic categories for creating intensional definitions of nursing diagnostic concepts in the MED. Because the MED does not include Focus and Judgment hierarchies, the authors developed them to define the nursing diagnostic concepts. Results: The ISO model was sufficient for dissecting the source terminologies into atomic terms. The authors identified 162 unique focus concepts from the 266 nursing diagnosis terms for inclusion in the Focus hierarchy. For the Judgment hierarchy, the authors precoordinated Judgment and Potentiality instead of using Potentiality as a qualifier of Judgment as in the ISO model. Impairment and Alteration were the most frequently occurring judgments. Conclusions: Nursing care represents a large proportion of health care activities; thus, it is vital that terms used by nurses are integrated into concept-oriented terminologies that provide broad coverage for the domain of health care. This study supports the utility of the ISO Reference Terminology Model for Nursing Diagnoses as a facilitator for the integration process. PMID:12668692

The health care learning organization.

PubMed

Hult, G T; Lukas, B A; Hult, A M

1996-01-01

To many health care executives, emphasis on marketing strategy has become a means of survival in the threatening new environment of cost attainment, intense competition, and prospective payment. This paper develops a positive model of the health care organization based on organizational learning theory and the concept of the health care offering. It is proposed that the typical health care organization represents the prototype of the learning organization. Thus, commitment to a shared vision is proposed to be an integral part of the health care organization and its diagnosis, treatment, and delivery of the health care offering, which is based on the exchange relationship, including its communicative environment. Based on the model, strategic marketing implications are discussed.

MODeLeR: A Virtual Constructivist Learning Environment and Methodology for Object-Oriented Design

ERIC Educational Resources Information Center

Coffey, John W.; Koonce, Robert

2008-01-01

This article contains a description of the organization and method of use of an active learning environment named MODeLeR, (Multimedia Object Design Learning Resource), a tool designed to facilitate the learning of concepts pertaining to object modeling with the Unified Modeling Language (UML). MODeLeR was created to provide an authentic,…

A Model for Predicting Late Prehistoric Architectural Sites at the Pinon Canyon Maneuver Site in Southeastern Colorado

DTIC Science & Technology

2007-01-01

Mark Owens 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES), 8. PERFORMING ORGANIZATION Department of Sociology and Anthropology REPORT NUMBER New...posit this type of behavior can be reflected in the spatial organization of architecture and to a lesser degree in artifacts. If true, by focusing the...social organization . To understand the role of architecture in larger cultural systems, several concepts, both theoretical and methodological, have to

Modeling of a 3DTV service in the software-defined networking architecture

NASA Astrophysics Data System (ADS)

Wilczewski, Grzegorz

2014-11-01

In this article a newly developed concept towards modeling of a multimedia service offering stereoscopic motion imagery is presented. Proposed model is based on the approach of utilization of Software-defined Networking or Software Defined Networks architecture (SDN). The definition of 3D television service spanning SDN concept is identified, exposing basic characteristic of a 3DTV service in a modern networking organization layout. Furthermore, exemplary functionalities of the proposed 3DTV model are depicted. It is indicated that modeling of a 3DTV service in the Software-defined Networking architecture leads to multiplicity of improvements, especially towards flexibility of a service supporting heterogeneity of end user devices.

Changing organisms in rapidly changing anthropogenic landscapes: the significance of the ‘Umwelt’-concept and functional habitat for animal conservation

PubMed Central

Van Dyck, Hans

2012-01-01

There is a growing recognition for the significance of evolutionary thinking in ecology and conservation biology. However, ecology and conservation studies often work with species-specific, fixed traits that ignore intraspecific variation. The way the habitat of a species is considered is an example of typological thinking biased by human perception. Structural habitat units (e.g., land cover types) as perceived by humans may not represent functional habitat units for other organisms. Human activity may also interfere with the environmental information used by organisms. Therefore, the Umwelt-concept from ethology needs to be integrated in the way we think about habitat and habitat selection. It states that different organisms live in different perceptual worlds dealing with specific subsamples of the environment as a result of their evolutionary and developmental history. The resource-based habitat concept is a functional habitat model based on resource distributions (consumables and conditions) and individual movements. This behavioural approach takes into account aspects that relate to the perceptual world of organisms. This approach may offer new opportunities for conservation and may help avoid failures with habitat restoration. Perceptual ability may be subject to adaptive change, but it may also constrain organisms from showing adaptive behaviours in rapidly changing environments. PMID:25568037

Changing organisms in rapidly changing anthropogenic landscapes: the significance of the 'Umwelt'-concept and functional habitat for animal conservation.

PubMed

Van Dyck, Hans

2012-02-01

There is a growing recognition for the significance of evolutionary thinking in ecology and conservation biology. However, ecology and conservation studies often work with species-specific, fixed traits that ignore intraspecific variation. The way the habitat of a species is considered is an example of typological thinking biased by human perception. Structural habitat units (e.g., land cover types) as perceived by humans may not represent functional habitat units for other organisms. Human activity may also interfere with the environmental information used by organisms. Therefore, the Umwelt-concept from ethology needs to be integrated in the way we think about habitat and habitat selection. It states that different organisms live in different perceptual worlds dealing with specific subsamples of the environment as a result of their evolutionary and developmental history. The resource-based habitat concept is a functional habitat model based on resource distributions (consumables and conditions) and individual movements. This behavioural approach takes into account aspects that relate to the perceptual world of organisms. This approach may offer new opportunities for conservation and may help avoid failures with habitat restoration. Perceptual ability may be subject to adaptive change, but it may also constrain organisms from showing adaptive behaviours in rapidly changing environments.

Personalized-detailed clinical model for data interoperability among clinical standards.

PubMed

Khan, Wajahat Ali; Hussain, Maqbool; Afzal, Muhammad; Amin, Muhammad Bilal; Saleem, Muhammad Aamir; Lee, Sungyoung

2013-08-01

Data interoperability among health information exchange (HIE) systems is a major concern for healthcare practitioners to enable provisioning of telemedicine-related services. Heterogeneity exists in these systems not only at the data level but also among different heterogeneous healthcare standards with which these are compliant. The relationship between healthcare organization data and different heterogeneous standards is necessary to achieve the goal of data level interoperability. We propose a personalized-detailed clinical model (P-DCM) approach for the generation of customized mappings that creates the necessary linkage between organization-conformed healthcare standards concepts and clinical model concepts to ensure data interoperability among HIE systems. We consider electronic health record (EHR) standards, openEHR, and HL7 CDA instances transformation using P-DCM. P-DCM concepts associated with openEHR and HL7 CDA help in transformation of instances among these standards. We investigated two datasets: (1) data of 100 diabetic patients, including 50 each of type 1 and type 2, from a local hospital in Korea and (2) data of a single Alzheimer's disease patient. P-DCMs were created for both scenarios, which provided the basis for deriving instances for HL7 CDA and openEHR standards. For proof of concept, we present case studies of encounter information for type 2 diabetes mellitus patients and monitoring of daily routine activities of an Alzheimer's disease patient. These reflect P-DCM-based customized mappings generation with openEHR and HL7 CDA standards. Customized mappings are generated based on the relationship of P-DCM concepts with CDA and openEHR concepts. The objective of this work is to achieve semantic data interoperability among heterogeneous standards. This would lead to effective utilization of resources and allow timely information exchange among healthcare systems.

Personalized-Detailed Clinical Model for Data Interoperability Among Clinical Standards

PubMed Central

Khan, Wajahat Ali; Hussain, Maqbool; Afzal, Muhammad; Amin, Muhammad Bilal; Saleem, Muhammad Aamir

2013-01-01

Abstract Objective: Data interoperability among health information exchange (HIE) systems is a major concern for healthcare practitioners to enable provisioning of telemedicine-related services. Heterogeneity exists in these systems not only at the data level but also among different heterogeneous healthcare standards with which these are compliant. The relationship between healthcare organization data and different heterogeneous standards is necessary to achieve the goal of data level interoperability. We propose a personalized-detailed clinical model (P-DCM) approach for the generation of customized mappings that creates the necessary linkage between organization-conformed healthcare standards concepts and clinical model concepts to ensure data interoperability among HIE systems. Materials and Methods: We consider electronic health record (EHR) standards, openEHR, and HL7 CDA instances transformation using P-DCM. P-DCM concepts associated with openEHR and HL7 CDA help in transformation of instances among these standards. We investigated two datasets: (1) data of 100 diabetic patients, including 50 each of type 1 and type 2, from a local hospital in Korea and (2) data of a single Alzheimer's disease patient. P-DCMs were created for both scenarios, which provided the basis for deriving instances for HL7 CDA and openEHR standards. Results: For proof of concept, we present case studies of encounter information for type 2 diabetes mellitus patients and monitoring of daily routine activities of an Alzheimer's disease patient. These reflect P-DCM-based customized mappings generation with openEHR and HL7 CDA standards. Customized mappings are generated based on the relationship of P-DCM concepts with CDA and openEHR concepts. Conclusions: The objective of this work is to achieve semantic data interoperability among heterogeneous standards. This would lead to effective utilization of resources and allow timely information exchange among healthcare systems. PMID:23875730

Mechanical simulators for training for laparoscopic surgery in urology.

PubMed

Rassweiler, Jens; Klein, Jan; Teber, Dogu; Schulze, Michael; Frede, Thomas

2007-03-01

The introduction of laparoscopic surgery into urology has led to new training concepts differing significantly from previous concepts of training for open surgery. This paper focuses on the type and importance of mechanical simulators in laparoscopic training. On the basis of our own studies and experience with the development of various concepts of laparoscopic training, including different modules (i.e., Pelvi-trainer, animal models, clinical mentoring) since 1991, we reviewed the current literature concerning all types of simulators. We focused on training for laparoscopic ablative and reconstructive surgery using mechanical simulators. The principle of a mechanical simulator (i.e., a box with the possibility of trocar insertion) has not changed during the last decade. However, the types of Pelvi-trainers and the models used inside have been improved significantly. According to the task of the simulator, various sophisticated models have been developed, including standardized phantoms, animal organs, and even perfused segments of porcine organs. For laparoscopic suturing, various step-by-step training concepts have been presented. These can be used for determination of the ability of a physician with an interest in laparoscopic surgery, but also to classify the training status of a laparosopic surgeon. Training in laparoscopic surgery has become an important topic, not only in learning a procedure, but also in maintaining skills and preparing for the management of complications. For these purposes, mechanical simulators will definitely play an important role in the future.

A Cybernetic Approach to the Modeling of Agent Communities

NASA Technical Reports Server (NTRS)

Truszkowski, Walt; Karlin, Jay

2000-01-01

In an earlier paper [1] examples of agent technology in a NASA context were presented. Both groundbased and space-based applications were addressed. This paper continues the discussion of one aspect of the Goddard Space Flight Center's continuing efforts to develop a community of agents that can support both ground-based and space-based systems autonomy. The paper focuses on an approach to agent-community modeling based on the theory of viable systems developed by Stafford Beer. It gives the status of an initial attempt to capture some of the agent-community behaviors in a viable system context. This paper is expository in nature and focuses on a discussion of the modeling of some of the underlying concepts and infrastructure that will serve as the basis of more detailed investigative work into the behavior of agent communities. The paper is organized as follows. First, a general introduction to agent community requirements is presented. Secondly, a brief introduction to the cybernetic concept of a viable system is given. This concept forms the foundation of the modeling approach. Then the concept of an agent community is modeled in the cybernetic context.

STEM based learning to facilitate middle school students’ conceptual change, creativity and collaboration in organization of living system topic

NASA Astrophysics Data System (ADS)

Rustaman, N. Y.; Afianti, E.; Maryati, S.

2018-05-01

A study using one group pre-post-test experimental design on Life organization system topic was carried out to investigate student’s tendency in learning abstract concept, their creativity and collaboration in designing and producing cell models through STEM-based learning. A number of seventh grade students in Cianjur district were involved as research subjects (n=34). Data were collected using two tier test for tracing changes in student conception before and after the application of STEM-based learning, and rubrics in creativity design (adopted from Torrance) and product on cell models (individually, in group), and rubric for self-assessment and observed skills on collaboration adapted from Marzano’s for life-long learning. Later the data obtained were analyzed qualitatively by interpreting the tendency of data presented in matrix sorted by gender. Research findings showed that the percentage of student’s scientific concept mastery is moderate in general. Their creativity in making a cell model design varied in category (expressing, emergent, excellent, not yet evident). Student’s collaboration varied from excellent, fair, good, less once, to less category in designing cell model. It was found that STEM based learning can facilitate students conceptual change, creativity and collaboration.

Perception of prescription medicine sample packs among Australian professional, government, industry, and consumer organizations, based on automated textual analysis of one-on-one interviews.

PubMed

Kyle, Greg J; Nissen, Lisa; Tett, Susan

2008-12-01

Prescription medicine samples provided by pharmaceutical companies are predominantly newer and more expensive products. The range of samples provided to practices may not represent the drugs that the doctors desire to have available. Few studies have used a qualitative design to explore the reasons behind sample use. The aim of this study was to explore the opinions of a variety of Australian key informants about prescription medicine samples, using a qualitative methodology. Twenty-three organizations involved in quality use of medicines in Australia were identified, based on the authors' previous knowledge. Each organization was invited to nominate 1 or 2 representatives to participate in semistructured interviews utilizing seeding questions. Each interview was recorded and transcribed verbatim. Leximancer v2.25 text analysis software (Leximancer Pty Ltd., Jindalee, Queensland, Australia) was used for textual analysis. The top 10 concepts from each analysis group were interrogated back to the original transcript text to determine the main emergent opinions. A total of 18 key interviewees representing 16 organizations participated. Samples, patient, doctor, and medicines were the major concepts among general opinions about samples. The concept drug became more frequent and the concept companies appeared when marketing issues were discussed. The Australian Pharmaceutical Benefits Scheme and cost were more prevalent in discussions about alternative sample distribution models, indicating interviewees were cognizant of budgetary implications. Key interviewee opinions added richness to the single-word concepts extracted by Leximancer. Participants recognized that prescription medicine samples have an influence on quality use of medicines and play a role in the marketing of medicines. They also believed that alternative distribution systems for samples could provide benefits. The cost of a noncommercial system for distributing samples or starter packs was a concern. These data will be used to design further research investigating alternative models for distribution of samples.

Personality from a cognitive-biological perspective.

PubMed

Neuman, Yair

2014-12-01

The term "personality" is used to describe a distinctive and relatively stable set of mental traits that aim to explain the organism's behavior. The concept of personality that emerged in human psychology has been also applied to the study of non-human organisms from birds to horses. In this paper, I critically review the concept of personality from an interdisciplinary perspective, and point to some ideas that may be used for developing a cognitive-biological theory of personality. Integrating theories and research findings from various fields such as cognitive ethnology, clinical psychology, and neuroscience, I argue that the common denominator of various personality theories are neural systems of threat/trust management and their emotional, cognitive, and behavioral dimensions. In this context, personality may be also conceived as a meta-heuristics both human and non-human organisms apply to model and predict the behavior of others. The paper concludes by suggesting a minimal computational model of personality that may guide future research. Copyright © 2014 Elsevier B.V. All rights reserved.

Safety climate and culture: Integrating psychological and systems perspectives.

PubMed

Casey, Tristan; Griffin, Mark A; Flatau Harrison, Huw; Neal, Andrew

2017-07-01

Safety climate research has reached a mature stage of development, with a number of meta-analyses demonstrating the link between safety climate and safety outcomes. More recently, there has been interest from systems theorists in integrating the concept of safety culture and to a lesser extent, safety climate into systems-based models of organizational safety. Such models represent a theoretical and practical development of the safety climate concept by positioning climate as part of a dynamic work system in which perceptions of safety act to constrain and shape employee behavior. We propose safety climate and safety culture constitute part of the enabling capitals through which organizations build safety capability. We discuss how organizations can deploy different configurations of enabling capital to exert control over work systems and maintain safe and productive performance. We outline 4 key strategies through which organizations to reconcile the system control problems of promotion versus prevention, and stability versus flexibility. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Teleomechanism redux? Functional physiology and hybrid models of life in early modern natural philosophy.

PubMed

Wolfe, Charles T

2014-01-01

The distinction between 'mechanical' and 'teleological' has been familiar since Kant; between a fully mechanistic, quantitative science of Nature and a teleological, qualitative approach to living beings, namely 'organisms' understood as purposive or at least functional entities. The beauty of this distinction is that it apparently makes intuitive sense and maps onto historico-conceptual constellations in the life sciences, regarding the status of the body versus that of the machine. I argue that the mechanism-teleology distinction is imprecise and flawed using examples including the 'functional' features present even in Cartesian physiology, the Oxford Physiologists' work on circulation and respiration, the fact that the model of the 'body-machine' is not a mechanistic reduction of organismic properties to basic physical properties but is focused on the uniqueness of organic life; and the concept of 'animal economy' in vitalist medicine, which I present as a 'teleomechanistic' concept of organism (borrowing a term of Lenoir's which he applied to nineteenth-century embryology)--neither mechanical nor teleological.

From Symbols, Stories and Social Artifacts to Social Architecture and Agency: The Discourse of Learning and the Decline of "Organizational Culture" in the "New Work Order."

ERIC Educational Resources Information Center

Siegel, Irwin H.

The concept of organizational culture has been central to the development of concepts, such as the learning organization and organizational learning, which are important within the field of adult education. However, the functionalist models of organizational culture, which have often relied on ethnographic and/or anecdotal studies of organizations…

Using Quality Management Methods in Knowledge-Based Organizations. An Approach to the Application of the Taguchi Method to the Process of Pressing Tappets into Anchors

NASA Astrophysics Data System (ADS)

Ţîţu, M. A.; Pop, A. B.; Ţîţu, Ș

2017-06-01

This paper presents a study on the modelling and optimization of certain variables by using the Taguchi Method with a view to modelling and optimizing the process of pressing tappets into anchors, process conducted in an organization that promotes knowledge-based management. The paper promotes practical concepts of the Taguchi Method and describes the way in which the objective functions are obtained and used during the modelling and optimization of the process of pressing tappets into the anchors.

Social Protocols for Agile Virtual Teams

NASA Astrophysics Data System (ADS)

Picard, Willy

Despite many works on collaborative networked organizations (CNOs), CSCW, groupware, workflow systems and social networks, computer support for virtual teams is still insufficient, especially support for agility, i.e. the capability of virtual team members to rapidly and cost efficiently adapt the way they interact to changes. In this paper, requirements for computer support for agile virtual teams are presented. Next, an extension of the concept of social protocol is proposed as a novel model supporting agile interactions within virtual teams. The extended concept of social protocol consists of an extended social network and a workflow model.

A Self-Critique of Self-Organized Criticality in Astrophysics

NASA Astrophysics Data System (ADS)

Aschwanden, Markus J.

2015-08-01

The concept of ``self-organized criticality'' (SOC) was originally proposed as an explanation of 1/f-noise by Bak, Tang, and Wiesenfeld (1987), but turned out to have a far broader significance for scale-free nonlinear energy dissipation processes occurring in the entire universe. Over the last 30 years, an inspiring cross-fertilization from complexity theory to solar and astrophysics took place, where the SOC concept was initially applied to solar flares, stellar flares, and magnetospheric substorms, and later extended to the radiation belt, the heliosphere, lunar craters, the asteroid belt, the Saturn ring, pulsar glitches, soft X-ray repeaters, blazars, black-hole objects, cosmic rays, and boson clouds. The application of SOC concepts has been performed by numerical cellular automaton simulations, by analytical calculations of statistical (powerlaw-like) distributions based on physical scaling laws, and by observational tests of theoretically predicted size distributions and waiting time distributions. Attempts have been undertaken to import physical models into numerical SOC toy models. The novel applications stimulated also vigorous debates about the discrimination between SOC-related and non-SOC processes, such as phase transitions, turbulence, random-walk diffusion, percolation, branching processes, network theory, chaos theory, fractality, multi-scale, and other complexity phenomena. We review SOC models applied to astrophysical observations, attempt to describe what physics can be captured by SOC models, and offer a critique of weaknesses and strengths in existing SOC models.

A Self-Critique of Self-Organized Criticality in Astrophysics

NASA Astrophysics Data System (ADS)

Aschwanden, Markus J.

The concept of ``self-organized criticality'' (SOC) was originally proposed as an explanation of 1/f-noise by Bak, Tang, and Wiesenfeld (1987), but turned out to have a far broader significance for scale-free nonlinear energy dissipation processes occurring in the entire universe. Over the last 30 years, an inspiring cross-fertilization from complexity theory to solar and astrophysics took place, where the SOC concept was initially applied to solar flares, stellar flares, and magnetospheric substorms, and later extended to the radiation belt, the heliosphere, lunar craters, the asteroid belt, the Saturn ring, pulsar glitches, soft X-ray repeaters, blazars, black-hole objects, cosmic rays, and boson clouds. The application of SOC concepts has been performed by numerical cellular automaton simulations, by analytical calculations of statistical (powerlaw-like) distributions based on physical scaling laws, and by observational tests of theoretically predicted size distributions and waiting time distributions. Attempts have been undertaken to import physical models into numerical SOC toy models. The novel applications stimulated also vigorous debates about the discrimination between SOC-related and non-SOC processes, such as phase transitions, turbulence, random-walk diffusion, percolation, branching processes, network theory, chaos theory, fractality, multi-scale, and other complexity phenomena. We review SOC models applied to astrophysical observations, attempt to describe what physics can be captured by SOC models, and offer a critique of weaknesses and strengths in existing SOC models.

Physics-based deformable organisms for medical image analysis

NASA Astrophysics Data System (ADS)

Hamarneh, Ghassan; McIntosh, Chris

2005-04-01

Previously, "Deformable organisms" were introduced as a novel paradigm for medical image analysis that uses artificial life modelling concepts. Deformable organisms were designed to complement the classical bottom-up deformable models methodologies (geometrical and physical layers), with top-down intelligent deformation control mechanisms (behavioral and cognitive layers). However, a true physical layer was absent and in order to complete medical image segmentation tasks, deformable organisms relied on pure geometry-based shape deformations guided by sensory data, prior structural knowledge, and expert-generated schedules of behaviors. In this paper we introduce the use of physics-based shape deformations within the deformable organisms framework yielding additional robustness by allowing intuitive real-time user guidance and interaction when necessary. We present the results of applying our physics-based deformable organisms, with an underlying dynamic spring-mass mesh model, to segmenting and labelling the corpus callosum in 2D midsagittal magnetic resonance images.

Competence-Based, Research-Related Lab Courses for Materials Modeling: The Case of Organic Photovoltaics

ERIC Educational Resources Information Center

Schellhammer, Karl Sebastian; Cuniberti, Gianaurelio

2017-01-01

We are hereby presenting a didactic concept for an advanced lab course that focuses on the design of donor materials for organic solar cells. Its research-related and competence-based approach qualifies the students to independently and creatively apply computational methods and to profoundly and critically discuss the results obtained. The high…

EvoluZion: A Computer Simulator for Teaching Genetic and Evolutionary Concepts

ERIC Educational Resources Information Center

Zurita, Adolfo R.

2017-01-01

EvoluZion is a forward-in-time genetic simulator developed in Java and designed to perform real time simulations on the evolutionary history of virtual organisms. These model organisms harbour a set of 13 genes that codify an equal number of phenotypic features. These genes change randomly during replication, and mutant genes can have null,…

Integrated modeling analysis of a novel hexapod and its application in active surface

NASA Astrophysics Data System (ADS)

Yang, Dehua; Zago, Lorenzo; Li, Hui; Lambert, Gregory; Zhou, Guohua; Li, Guoping

2011-09-01

This paper presents the concept and integrated modeling analysis of a novel mechanism, a 3-CPS/RPPS hexapod, for supporting segmented reflectors for radio telescopes and eventually segmented mirrors of optical telescopes. The concept comprises a novel type of hexapod with an original organization of actuators hence degrees of freedom, based on a swaying arm based design concept. Afterwards, with specially designed connecting joints between panels/segments, an iso-static master-slave active surface concept can be achieved for any triangular and/or hexagonal panel/segment pattern. The integrated modeling comprises all the multifold sizing and performance aspects which must be evaluated concurrently in order to optimize and validate the design and the configuration. In particular, comprehensive investigation of kinematic behavior, dynamic analysis, wave-front error and sensitivity analysis are carried out, where, frequently used tools like MATLAB/SimMechanics, CALFEM and ANSYS are used. Especially, we introduce the finite element method as a competent approach for analyses of the multi-degree of freedom mechanism. Some experimental verifications already performed validating single aspects of the integrated concept are also presented with the results obtained.

Demands on Intranets — Viable System Model as a Foundation for Intranet Design

NASA Astrophysics Data System (ADS)

Amcoff Nyström, Christina

2006-06-01

The number of Intranets increases in organizations but their potential to support viability is not fully exploited. The cybernetic model, the Viable System Model, has not been connected to the Intranet concept before. Characteristics of the VSM, such as highlighting the importance of production, monitoring of production units through Early Warning Systems, autonomy and empowerment, are used as patterns and a base for de-signing essential parts and/or functions of an Intranet. The result is a brief description of functions vital to the operational parts of organizations. Examples are Early Warning Systems, control systems, "gate-keepers," amplifying and damping information to and from the organization and "agents" supporting search abilities on an Intranet.

The Social Responsibility Performance Outcomes Model: Building Socially Responsible Companies through Performance Improvement Outcomes.

ERIC Educational Resources Information Center

Hatcher, Tim

2000-01-01

Considers the role of performance improvement professionals and human resources development professionals in helping organizations realize the ethical and financial power of corporate social responsibility. Explains the social responsibility performance outcomes model, which incorporates the concepts of societal needs and outcomes. (LRW)

Modeling-Mainstreaming: A Teacher Training Proposal.

ERIC Educational Resources Information Center

Bireley, Marlene; Mahan, Virginia

This document presents a learning model for training teachers to effectively deal with physically handicapped and mildly retarded children in their regular classroom. The modules are organized in the following fashion: Phase One; Development of an awareness of the concept of mainstreaming, of labels and their consequences, and of the psychological…

Neighbors United for Health

ERIC Educational Resources Information Center

Westhoff, Wayne W.; Corvin, Jaime; Virella, Irmarie

2009-01-01

Modeled upon the ecclesiastic community group concept of Latin America to unite and strengthen the bond between the Church and neighborhoods, a community-based organization created Vecinos Unidos por la Salud (Neighbors United for Health) to bring health messages into urban Latino neighborhoods. The model is based on five tenants, and incorporates…

Improving Organizational Effectiveness through Transformational Leadership.

ERIC Educational Resources Information Center

Bass, Bernard M., Ed.; Avolio, Bruce J., Ed.

This book shows how transformational leadership is expected to contribute to an organization's efforts to improve its operations and the best use of its human resources. The concepts of transactional and transformational leadership are introduced within the framework of a full-range model of leadership. This model is applied to research,…

Teaching Complex Concepts in the Geosciences by Integrating Analytical Reasoning with GIS

ERIC Educational Resources Information Center

Houser, Chris; Bishop, Michael P.; Lemmons, Kelly

2017-01-01

Conceptual models have long served as a means for physical geographers to organize their understanding of feedback mechanisms and complex systems. Analytical reasoning provides undergraduate students with an opportunity to develop conceptual models based upon their understanding of surface processes and environmental conditions. This study…

Concept mapping as an approach for expert-guided model building: The example of health literacy.

PubMed

Soellner, Renate; Lenartz, Norbert; Rudinger, Georg

2017-02-01

Concept mapping served as the starting point for the aim of capturing the comprehensive structure of the construct of 'health literacy.' Ideas about health literacy were generated by 99 experts and resulted in 105 statements that were subsequently organized by 27 experts in an unstructured card sorting. Multidimensional scaling was applied to the sorting data and a two and three-dimensional solution was computed. The three dimensional solution was used in subsequent cluster analysis and resulted in a concept map of nine "clusters": (1) self-regulation, (2) self-perception, (3) proactive approach to health, (4) basic literacy and numeracy skills, (5) information appraisal, (6) information search, (7) health care system knowledge and acting, (8) communication and cooperation, and (9) beneficial personality traits. Subsequently, this concept map served as a starting point for developing a "qualitative" structural model of health literacy and a questionnaire for the measurement of health literacy. On the basis of questionnaire data, a "quantitative" structural model was created by first applying exploratory factor analyses (EFA) and then cross-validating the model with confirmatory factor analyses (CFA). Concept mapping proved to be a highly valuable tool for the process of model building up to translational research in the "real world". Copyright © 2016 Elsevier Ltd. All rights reserved.

Lean Management—The Journey from Toyota to Healthcare

PubMed Central

Teich, Sorin T.; Faddoul, Fady F.

2013-01-01

The evolution of production systems is tightly linked to the story of Toyota Motor Company (TMC) that has its roots around 1918. The term “lean” was coined in 1990 following the exploration of the Toyota model that led to the “transference” thesis sustaining the concept that manufacturing problems and technologies are universal problems faced by management and that these concepts can be emulated in non-Japanese enterprises. Lean is a multi-faceted concept and requires organizations to exert effort along several dimensions simultaneously; some consider a successful implementation either achieving major strategic components of lean, implementing practices to support operational aspects, or providing evidence that the improvements are sustainable in the long term. The article explores challenges and opportunities faced by organizations that intend incorporating lean management principles and presents the specific context of the healthcare industry. Finally, the concepts of “essential few” and customer value are illustrated through a simple example of process change following lean principles, which was implemented in a dental school in the United States. PMID:23908857

Lean management-the journey from toyota to healthcare.

PubMed

Teich, Sorin T; Faddoul, Fady F

2013-04-01

The evolution of production systems is tightly linked to the story of Toyota Motor Company (TMC) that has its roots around 1918. The term "lean" was coined in 1990 following the exploration of the Toyota model that led to the "transference" thesis sustaining the concept that manufacturing problems and technologies are universal problems faced by management and that these concepts can be emulated in non-Japanese enterprises. Lean is a multi-faceted concept and requires organizations to exert effort along several dimensions simultaneously; some consider a successful implementation either achieving major strategic components of lean, implementing practices to support operational aspects, or providing evidence that the improvements are sustainable in the long term. The article explores challenges and opportunities faced by organizations that intend incorporating lean management principles and presents the specific context of the healthcare industry. Finally, the concepts of "essential few" and customer value are illustrated through a simple example of process change following lean principles, which was implemented in a dental school in the United States.

Proposed Core Competencies and Empirical Validation Procedure in Competency Modeling: Confirmation and Classification

PubMed Central

Baczyńska, Anna K.; Rowiński, Tomasz; Cybis, Natalia

2016-01-01

Competency models provide insight into key skills which are common to many positions in an organization. Moreover, there is a range of competencies that is used by many companies. Researchers have developed core competency terminology to underline their cross-organizational value. The article presents a theoretical model of core competencies consisting of two main higher-order competencies called performance and entrepreneurship. Each of them consists of three elements: the performance competency includes cooperation, organization of work and goal orientation, while entrepreneurship includes innovativeness, calculated risk-taking and pro-activeness. However, there is lack of empirical validation of competency concepts in organizations and this would seem crucial for obtaining reliable results from organizational research. We propose a two-step empirical validation procedure: (1) confirmation factor analysis, and (2) classification of employees. The sample consisted of 636 respondents (M = 44.5; SD = 15.1). Participants were administered a questionnaire developed for the study purpose. The reliability, measured by Cronbach’s alpha, ranged from 0.60 to 0.83 for six scales. Next, we tested the model using a confirmatory factor analysis. The two separate, single models of performance and entrepreneurial orientations fit quite well to the data, while a complex model based on the two single concepts needs further research. In the classification of employees based on the two higher order competencies we obtained four main groups of employees. Their profiles relate to those found in the literature, including so-called niche finders and top performers. Some proposal for organizations is discussed. PMID:27014111

Why business models matter.

PubMed

Magretta, Joan

2002-05-01

"Business model" was one of the great buzz-words of the Internet boom. A company didn't need a strategy, a special competence, or even any customers--all it needed was a Web-based business model that promised wild profits in some distant, ill-defined future. Many people--investors, entrepreneurs, and executives alike--fell for the fantasy and got burned. And as the inevitable counterreaction played out, the concept of the business model fell out of fashion nearly as quickly as the .com appendage itself. That's a shame. As Joan Magretta explains, a good business model remains essential to every successful organization, whether it's a new venture or an established player. To help managers apply the concept successfully, she defines what a business model is and how it complements a smart competitive strategy. Business models are, at heart, stories that explain how enterprises work. Like a good story, a robust business model contains precisely delineated characters, plausible motivations, and a plot that turns on an insight about value. It answers certain questions: Who is the customer? How do we make money? What underlying economic logic explains how we can deliver value to customers at an appropriate cost? Every viable organization is built on a sound business model, but a business model isn't a strategy, even though many people use the terms interchangeably. Business models describe, as a system, how the pieces of a business fit together. But they don't factor in one critical dimension of performance: competition. That's the job of strategy. Illustrated with examples from companies like American Express, EuroDisney, WalMart, and Dell Computer, this article clarifies the concepts of business models and strategy, which are fundamental to every company's performance.

Management: Curse, Cure-All, or Workable Concept?

ERIC Educational Resources Information Center

Prentice, Marjorie

1973-01-01

In order for curriculum workers to plan and organize in an orderly, rational manner, an operating model is described which identifies the necessary components of the system and clearly states relationships between such components. (Author/CB)

Digital Platforms as Factor Transforming Management Models in Businesses and Industries

NASA Astrophysics Data System (ADS)

Dimitrakiev, D.; Molodchik, A. V.

2018-05-01

Increasingly, digital platforms are built into the value chain, acting as an intermediary between the manufacturer and the consumer. The paper presents tendencies and features of business model transformation in connection with management of the new digital technologies. The limitations of traditional business models and the capabilities of business models based on digital platforms and self-organization were revealed. In the study, the viability of the new business model for the dental industry was confirmed and the new concept of the branch self-organizing control system based on the information platform, blockchain, cryptocurrency and reward of target consumer is offered, including mechanisms that make the model attractive for both the consumer and the service provider.

Innovative Educational Restructuring for America 2000: Time To Bury Political Bureaucracies and Begin Systematic Assessment, Profiling & Technological Improvement of School Organizations.

ERIC Educational Resources Information Center

Packard, Richard D.; Dereshiwsky, Mary I.

Despite current interest with the concept of the "New American School" model discussed in "America 2000," school systems continue to approach educational reform and restructuring by tinkering with key organizational components in isolation. The total school organization requires assessment and profiling to determine which key components are drags…

A model-driven approach to information security compliance

NASA Astrophysics Data System (ADS)

Correia, Anacleto; Gonçalves, António; Teodoro, M. Filomena

2017-06-01

The availability, integrity and confidentiality of information are fundamental to the long-term survival of any organization. Information security is a complex issue that must be holistically approached, combining assets that support corporate systems, in an extended network of business partners, vendors, customers and other stakeholders. This paper addresses the conception and implementation of information security systems, conform the ISO/IEC 27000 set of standards, using the model-driven approach. The process begins with the conception of a domain level model (computation independent model) based on information security vocabulary present in the ISO/IEC 27001 standard. Based on this model, after embedding in the model mandatory rules for attaining ISO/IEC 27001 conformance, a platform independent model is derived. Finally, a platform specific model serves the base for testing the compliance of information security systems with the ISO/IEC 27000 set of standards.

A Counselling Model for Young Women in the United Arab Emirates: Cultural Considerations

ERIC Educational Resources Information Center

Lambert, Louise

2008-01-01

Although all modalities of therapy work equally well, some models are better suited to work with specific populations. This article outlines a rationale for a counselling model used for female college students in the United Arab Emirates where the concept of counselling is not well known, and where the social and cultural organizations demand a…

A family systems-based model of organizational intervention.

PubMed

Shumway, Sterling T; Kimball, Thomas G; Korinek, Alan W; Arredondo, Rudy

2007-04-01

Employee assistance professionals are expected to be proficient at intervening in organizations and creating meaningful behavioral change in interpersonal functioning. Because of their training in family systems theories and concepts, marriage and family therapists (MFTs) are well suited to serve organizations as "systems consultants." Unfortunately, the authors were unable to identify any family systems-based models for organizational intervention that have been empirically tested and supported. In this article, the authors present a family systems-based model of intervention that they developed while working in an employee assistance program (EAP). They also present research that was used to refine the model and to provide initial support for its effectiveness.

XFEM-based modeling of successive resections for preoperative image updating

NASA Astrophysics Data System (ADS)

Vigneron, Lara M.; Robe, Pierre A.; Warfield, Simon K.; Verly, Jacques G.

2006-03-01

We present a new method for modeling organ deformations due to successive resections. We use a biomechanical model of the organ, compute its volume-displacement solution based on the eXtended Finite Element Method (XFEM). The key feature of XFEM is that material discontinuities induced by every new resection can be handled without remeshing or mesh adaptation, as would be required by the conventional Finite Element Method (FEM). We focus on the application of preoperative image updating for image-guided surgery. Proof-of-concept demonstrations are shown for synthetic and real data in the context of neurosurgery.

Organic Chemistry Educators' Perspectives on Fundamental Concepts and Misconceptions: An Exploratory Study

ERIC Educational Resources Information Center

Duis, Jennifer M.

2011-01-01

An exploratory study was conducted with 23 organic chemistry educators to discover what general chemistry concepts they typically review, the concepts they believe are fundamental to introductory organic chemistry, the topics students find most difficult in the subject, and the misconceptions they observe in undergraduate organic chemistry…

Associating Human-Centered Concepts with Social Networks Using Fuzzy Sets

NASA Astrophysics Data System (ADS)

Yager, Ronald R.

The rapidly growing global interconnectivity, brought about to a large extent by the Internet, has dramatically increased the importance and diversity of social networks. Modern social networks cut across a spectrum from benign recreational focused websites such as Facebook to occupationally oriented websites such as LinkedIn to criminally focused groups such as drug cartels to devastation and terror focused groups such as Al-Qaeda. Many organizations are interested in analyzing and extracting information related to these social networks. Among these are governmental police and security agencies as well marketing and sales organizations. To aid these organizations there is a need for technologies to model social networks and intelligently extract information from these models. While established technologies exist for the modeling of relational networks [1-7] few technologies exist to extract information from these, compatible with human perception and understanding. Data bases is an example of a technology in which we have tools for representing our information as well as tools for querying and extracting the information contained. Our goal is in some sense analogous. We want to use the relational network model to represent information, in this case about relationships and interconnections, and then be able to query the social network using intelligent human-centered concepts. To extend our capabilities to interact with social relational networks we need to associate with these network human concepts and ideas. Since human beings predominantly use linguistic terms in which to reason and understand we need to build bridges between human conceptualization and the formal mathematical representation of the social network. Consider for example a concept such as "leader". An analyst may be able to express, in linguistic terms, using a network relevant vocabulary, properties of a leader. Our task is to translate this linguistic description into a mathematical formalism that allows us to determine how true it is that a particular node is a leader. In this work we look at the use of fuzzy set methodologies [8-10] to provide a bridge between the human analyst and the formal model of the network.

Computer Technology-Integrated Projects Should not Supplant Craft Projects in Science Education

NASA Astrophysics Data System (ADS)

Klopp, Tabatha J.; Rule, Audrey C.; Suchsland Schneider, Jean; Boody, Robert M.

2014-03-01

The current emphasis on computer technology integration and narrowing of the curriculum has displaced arts and crafts. However, the hands-on, concrete nature of craft work in science modeling enables students to understand difficult concepts and to be engaged and motivated while learning spatial, logical, and sequential thinking skills. Analogy use is also helpful in understanding unfamiliar, complex science concepts. This study of 28 academically advanced elementary to middle-school students examined student work and perceptions during a science unit focused on four fossil organisms: crinoid, brachiopod, horn coral and trilobite. The study compared: (1) analogy-focused instruction to independent Internet research and (2) computer technology-rich products to crafts-based products. Findings indicate student products were more creative after analogy-based instruction and when made using technology. However, students expressed a strong desire to engage in additional craft work after making craft products and enjoyed making crafts more after analogy-focused instruction. Additionally, more science content was found in the craft products than the technology-rich products. Students expressed a particular liking for two of the fossil organisms because they had been modeled with crafts. The authors recommend that room should be retained for crafts in the science curriculum to model science concepts.

The concept of "psychosomatic" in general practice. Reflections on body language and a tentative model for understanding.

PubMed

Mattsson, Bengt; Mattsson, Monica

2002-09-01

In medicine, the concept "psychosomatic" indicates both dualism and polarisation. "Could it mean something psychic or is it something somatic?" This artificial dichotomy and body/mind split is not as apparent in general practice as it is in other medical disciplines. In general practice, the prerequisites for a division are overlooked. Following the work of Piaget, the article outlines manifestations of a body/mind unity as exposed in the language. Words and expressions describing the way we move, stand and walk therefore indicate our attitude and state of mind. Our body language conveys a message. The importance of breathing and its relation to our emotions is highlighted. The function of breathing is said to represent a bridge between the conscious and the unconscious--breathing can be controlled by our will, but generally we breathe reflexively. Restricted breathing is not just a mechanical process; it is shown that there is a connection between breathing and our emotions. Finally, a model of the "human organism" is presented linking four concepts, "human activity", "organ functions", "physical body" and "neurophysiological functions". Activities within the different systems are linked and relate to each other. The model supports the necessity to overcome the body/mind split, which is one of the obstacles to the fulfillment of good quality general practice.

Treating Pompe Disease

ERIC Educational Resources Information Center

Bokor, Julie; Joseph, Drew; Darwiche, Houda

2015-01-01

One of the crosscutting concepts in science is cause and effect. A disease model can provide understanding of cause and effect, as teachers scaffold student thinking from molecular changes in the DNA to visible traits in the organism. The project described in this article uses Pompe disease, a rare recessive disorder, as a model of cause and…

Mathematical Analysis of a Multiple-Look Concept Identification Model.

ERIC Educational Resources Information Center

Cotton, John W.

The behavior of focus samples central to the multiple-look model of Trabasso and Bower is examined by three methods. First, exact probabilities of success conditional upon a certain brief history of stimulation are determined. Second, possible states of the organism during the experiment are defined and a transition matrix for those states…

Students' Individual Schematization Pathways--Empirical Reconstructions for the Case of Part-of-Part Determination for Fractions

ERIC Educational Resources Information Center

Glade, Matthias; Prediger, Susanne

2017-01-01

According to the design principle of progressive schematization, learning trajectories towards procedural rules can be organized as independent discoveries when the learning arrangement invites the students first to develop models for mathematical concepts and model-based informal strategies; then to explore the strategies and to discover pattern…

Burton Clark's "The Higher Education System: Academic Organization in Cross-National Perspective"

ERIC Educational Resources Information Center

Brennan, John

2010-01-01

In "The Higher Education System", Burton Clark provides a model for the organisational analysis of higher education institutions and systems. Central to the model are the concepts of knowledge, beliefs and authority. In particular, Clark examines how different interest groups both inside and outside the university shape and subvert the…

Analyzing Change in Students' Gene-to-Evolution Models in College-Level Introductory Biology

ERIC Educational Resources Information Center

Dauer, Joseph T.; Momsen, Jennifer L.; Speth, Elena Bray; Makohon-Moore, Sasha C.; Long, Tammy M.

2013-01-01

Research in contemporary biology has become increasingly complex and organized around understanding biological processes in the context of systems. To better reflect the ways of thinking required for learning about systems, we developed and implemented a pedagogical approach using box-and-arrow models (similar to concept maps) as a foundational…

Implementation of Cooperative Learning Model in Preschool

ERIC Educational Resources Information Center

Akçay, Nilüfer Okur

2016-01-01

In this study, the effectivity of jigsaw method, one of the cooperative learning models, on teaching the concepts related to sense organs and their functions to four-five year-old children in nursery class was analyzed. The study is in the semi-experimental design consisting of experimental and control groups and pretest and posttest. The sample…

Satellite power system (SPS) financial/management scenarios

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1978-10-01

The problems of financing and managing a large-scale, lengthy SPS program reduce to the key questions of ownership and control. Ownership (that is, the sources of capital) may be governmental, corporate, or individual; control may be exercised by a government agency, a government-sanctioned monopoly, or a competitive corporation. Since the R and D phase and the commercial implementation phase of an SPS program are qualitatively very different with respect to length of time before return-on-investment, we have considered two general categories of SPS organizations: (1) organizations capable of carrying out a complete SPS program, from R and D through commercialization;more » (2) organizations capable of carrying out commercial implementation only. Six organizational models for carrying out the complete SPS program have been examined in some detail: 1) existing government agencies (DOE, NASA, etc.); 2) a new government agency, patterned after TVA; 3) a taxpayer stock corporation, a new concept; 4) a trust fund supported by energy taxes, patterned after the financing of the Interstate Highway System; 5) a federal agency financed by bonds, patterned after the Federal National Mortgage Association; and 6) the staging company, a new concept, already in the early stages of implementation as a private venture. Four additional organizational forms have been considered for commercial implementation of SPS: 7) a government-chartered monopoly, patterned after the Communications Satellite Corporation; 8) the consortium model, already widely used for large-scale projects; 9) the corporate socialism model, patterned after such developments as the transcontinental railroad; and 10) the universal capitalism model, a concept partially implemented in the 1976 legislation creating Employee Stock Ownership Plans. A number of qualitative criteria for comparative assessment of these alternatives have been developed.« less

Fractionations of rare earth elements in plants and their conceptive model.

PubMed

Ding, ShiMing; Liang, Tao; Yan, JunCai; Zhang, ZiLi; Huang, ZeChun; Xie, YaNing

2007-02-01

Fractionations of rare earth elements (REEs) and their mechanisms in soybean were studied through application of exogenous mixed REEs under hydroponic conditions. Significant enrichment of middle REEs (MREEs) and heavy REEs (HREEs) was observed in plant roots and leaves respectively, with slight fractionation between light REEs (LREEs) and HREEs in stems. Moreover, the tetrad effect was observed in these organs. Investigations into REE speciation in roots and in the xylem sap using X-ray absorption spectroscopy (XAS) and nanometer-sized TiO2 adsorption techniques, associated with other controlled experiments, demonstrated that REE fractionations should be dominated by fixation mechanism in roots caused by cell wall absorption and phosphate precipitation, and by the combined effects of fixation mechanism and transport mechanism in aboveground parts caused by solution complexation by intrinsic organic ligands. A conceptive model was established for REE fractionations in plants based on the above studies.

A systems-theoretical framework for health and disease: inflammation and preconditioning from an abstract modeling point of view.

PubMed

Voit, Eberhard O

2009-01-01

Modern advances in molecular biology have produced enormous amounts of data characterizing physiological and disease states in cells and organisms. While bioinformatics has facilitated the organizing and mining of these data, it is the task of systems biology to merge the available information into dynamic, explanatory and predictive models. This article takes a step into this direction. It proposes a conceptual approach toward formalizing health and disease and illustrates it in the context of inflammation and preconditioning. Instead of defining health and disease states, the emphasis is on simplexes in a high-dimensional biomarker space. These simplexes are bounded by physiological constraints and permit the quantitative characterization of personalized health trajectories, health risk profiles that change with age, and the efficacy of different treatment options. The article mainly focuses on concepts but also briefly describes how the proposed concepts might be formulated rigorously within a mathematical framework.

Acquired immunologic tolerance: with particular reference to transplantation

PubMed Central

Starzl, Thomas E.

2009-01-01

The first unequivocally successful bone marrow cell transplantation in humans was recorded in 1968 by the University of Minnesota team of Robert A. Good (Gatti et al. Lancet 2: 1366–1369, 1968). This achievement was a direct extension of mouse models of acquired immunologic tolerance that were established 15 years earlier. In contrast, organ (i.e. kidney) transplantation was accomplished precociously in humans (in 1959) before demonstrating its feasibility in any experimental model and in the absence of a defensible immunologic rationale. Due to the striking differences between the outcomes with the two kinds of procedure, the mechanisms of organ engraftment were long thought to differ from the leukocyte chimerism-associated ones of bone marrow transplantation. This and other concepts of alloengraftment and acquired tolerance have changed over time. Current concepts and their clinical implications can be understood and discussed best from the perspective provided by the life and times of Bob Good. PMID:17917005

The concept of self-organizing systems. Why bother?

NASA Astrophysics Data System (ADS)

Elverfeldt, Kirsten v.; Embleton-Hamann, Christine; Slaymaker, Olav

2016-04-01

Complexity theory and the concept of self-organizing systems provide a rather challenging conceptual framework for explaining earth systems change. Self-organization - understood as the aggregate processes internal to an environmental system that lead to a distinctive spatial or temporal organization - reduces the possibility of implicating a specific process as being causal, and it poses some restrictions on the idea that external drivers cause a system to change. The concept of self-organizing systems suggests that many phenomena result from an orchestration of different mechanisms, so that no causal role can be assigned to an individual factor or process. The idea that system change can be due to system-internal processes of self-organization thus proves a huge challenge to earth system research, especially in the context of global environmental change. In order to understand the concept's implications for the Earth Sciences, we need to know the characteristics of self-organizing systems and how to discern self-organizing systems. Within the talk, we aim firstly at characterizing self-organizing systems, and secondly at highlighting the advantages and difficulties of the concept within earth system sciences. The presentation concludes that: - The concept of self-organizing systems proves especially fruitful for small-scale earth surface systems. Beach cusps and patterned ground are only two of several other prime examples of self-organizing earth surface systems. They display characteristics of self-organization like (i) system-wide order from local interactions, (ii) symmetry breaking, (iii) distributed control, (iv) robustness and resilience, (v) nonlinearity and feedbacks, (vi) organizational closure, (vii) adaptation, and (viii) variation and selection. - It is comparatively easy to discern self-organization in small-scale systems, but to adapt the concept to larger scale systems relevant to global environmental change research is more difficult: Self-organizing systems seem to form nested hierarchies, and on different hierarchical levels self-organizing and externally driven subsystems might occur simultaneously. - Traditional geomorphological concepts such as sensitivity to change, and intrinsic or extrinsic thresholds are compatible with the concept of self-organizing system, and these concepts are even enriched in their explanatory power when viewed in the larger framework of self-organization. The conceptual step to acknowledge self-organizing system change within earth system sciences thus can be regarded as relatively small. The concept of self-organization suggests a change of focus for earth system change research: a shift from input-output relations toward the inner organization of systems, since external controls rather limit the degrees of freedom of a system instead of triggering changes. Many systems might in fact be rather autonomous, and the specific and observable external trigger might be less important than the intrinsic system state. Hence, neither gradual nor catastrophic system changes necessarily need an external driver. The concept of self-organization provides important caveats to generally attributing environmental change to external drivers, and it encourages a frank admission of ignorance in the face of complexity.

Computational optimization and biological evolution.

PubMed

Goryanin, Igor

2010-10-01

Modelling and optimization principles become a key concept in many biological areas, especially in biochemistry. Definitions of objective function, fitness and co-evolution, although they differ between biology and mathematics, are similar in a general sense. Although successful in fitting models to experimental data, and some biochemical predictions, optimization and evolutionary computations should be developed further to make more accurate real-life predictions, and deal not only with one organism in isolation, but also with communities of symbiotic and competing organisms. One of the future goals will be to explain and predict evolution not only for organisms in shake flasks or fermenters, but for real competitive multispecies environments.

Genome-Based Models to Optimize In Situ Bioremediation of Uranium and Harvesting Electrical Energy from Waste Organic Matter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lovley, Derek R

2012-12-28

The goal of this research was to provide computational tools to predictively model the behavior of two microbial communities of direct relevance to Department of Energy interests: 1) the microbial community responsible for in situ bioremediation of uranium in contaminated subsurface environments; and 2) the microbial community capable of harvesting electricity from waste organic matter and renewable biomass. During this project the concept of microbial electrosynthesis, a novel form of artificial photosynthesis for the direct production of fuels and other organic commodities from carbon dioxide and water was also developed and research was expanded into this area as well.

Re-evaluation of the sorption behaviour of Bromide and Sulfamethazine under field conditions using leaching data and modelling methods

NASA Astrophysics Data System (ADS)

Gassmann, Matthias; Olsson, Oliver; Höper, Heinrich; Hamscher, Gerd; Kümmerer, Klaus

2016-04-01

The simulation of reactive transport in the aquatic environment is hampered by the ambiguity of environmental fate process conceptualizations for a specific substance in the literature. Concepts are usually identified by experimental studies and inverse modelling under controlled lab conditions in order to reduce environmental uncertainties such as uncertain boundary conditions and input data. However, since environmental conditions affect substance behaviour, a re-evaluation might be necessary under environmental conditions which might, in turn, be affected by uncertainties. Using a combination of experimental data and simulations of the leaching behaviour of the veterinary antibiotic Sulfamethazine (SMZ; synonym: sulfadimidine) and the hydrological tracer Bromide (Br) in a field lysimeter, we re-evaluated the sorption concepts of both substances under uncertain field conditions. Sampling data of a field lysimeter experiment in which both substances were applied twice a year with manure and sampled at the bottom of two lysimeters during three subsequent years was used for model set-up and evaluation. The total amount of leached SMZ and Br were 22 μg and 129 mg, respectively. A reactive transport model was parameterized to the conditions of the two lysimeters filled with monoliths (depth 2 m, area 1 m²) of a sandy soil showing a low pH value under which Bromide is sorptive. We used different sorption concepts such as constant and organic-carbon dependent sorption coefficients and instantaneous and kinetic sorption equilibrium. Combining the sorption concepts resulted in four scenarios per substance with different equations for sorption equilibrium and sorption kinetics. The GLUE (Generalized Likelihood Uncertainty Estimation) method was applied to each scenario using parameter ranges found in experimental and modelling studies. The parameter spaces for each scenario were sampled using a Latin Hypercube method which was refined around local model efficiency maxima. Results of the cumulative SMZ leaching simulations suggest a best conceptualization combination of instantaneous sorption to organic carbon which is consistent with the literature. The best Nash-Sutcliffe efficiency (Neff) was 0.96 and the 5th and 95th percentile of the uncertainty estimation were 18 and 27 μg. In contrast, both scenarios of kinetic Br sorption had similar results (Neff =0.99, uncertainty bounds 110-176 mg and 112-176 mg) but were clearly better than instantaneous sorption scenarios. Therefore, only the concept of sorption kinetics could be identified for Br modelling whereas both tested sorption equilibrium coefficient concepts performed equally well. The reasons for this specific case of equifinality may be uncertainties of model input data under field conditions or an insensitivity of the sorption equilibrium method due to relatively low adsorption of Br. Our results show that it may be possible to identify or at least falsify specific sorption concepts under uncertain field conditions using a long-term leaching experiment and modelling methods. Cases of environmental fate concept equifinality arouse the possibility of future model structure uncertainty analysis using an ensemble of models with different environmental fate concepts.

A social skills analysis in childhood and adolescence using symbolic interactionism.

PubMed

Russell, A

1984-02-01

Support is obtained from the literature about the need for advances in the conceptualization of "social skills." There is agreement that much is known about how to improve social skills, but less attention has been given to what to change or improve. The present article outlines a model of social skills in childhood and adolescence using the concepts and literature on symbolic interactionism in an attempt to provide a possible conceptual framework for social skills. The proposed model is organized around the concepts of role-taking, role-making, definition of the situation, and self. Each concept is taken in turn and how it could contribute to the analysis or understanding of social skills in childhood and adolescence is shown. The article concludes with a discussion of ways in which the proposed scheme might be used in one area of social skills - friendship making. Some possible difficulties and limitations in the model are noted.

The Thinking Process Of Field Independent Cognitive Style Of Junior High School Student In Defining Quadrilateral Concept

NASA Astrophysics Data System (ADS)

Rahaju, E. B.

2018-01-01

Defining a quadrilateral concept is one part of mathematics learning in junior high school. Defining a concept can be influenced by the concept’s image. While the image of the concept is influenced by the experience associated with the concept, the characteristics of the concept, the mental picture of the concept, and the reconstruction of the definition made by the person against a concept. The thinking process of a person in defining a concept is influenced by cognitive style. This study aimed to describe the thinking process of a student in defining the quadrilateral concept based on her cognitive style. The subject of this research was a student on grade VII with Field Independent cognitive style (FI). This research concludes that the subject of FI in defining quadrilateral concepts, begins by forming a sense through listing the characteristics of quadrilateral. In determining the characteristics of a quadrilateral, subjects tend to organize all quadrilateral models that have been grouped. This suggests that the subject of FI is easier to capture the similarities found in the models that have been grouped. Based on the characteristics, the subject can conclude to make a simple definition of a quadrilateral by eliminating one by one characteristic are not essential. Subjects can make definitions that meet necessary and sufficient conditions on square, rectangular, parallelogram and trapezoid.

Self-Concept Structure and the Quality of Self-Knowledge.

PubMed

Showers, Carolin J; Ditzfeld, Christopher P; Zeigler-Hill, Virgil

2015-10-01

This article explores the hidden vulnerability of individuals with compartmentalized self-concept structures by linking research on self-organization to related models of self-functioning. Across three studies, college students completed self-descriptive card sorts as a measure of self-concept structure and either the Contingencies of Self-Worth Scale, Likert ratings of perceived authenticity of self-aspects, or a response latency measure of self-esteem accessibility. In all, there were 382 participants (247 females; 77% White, 6% Hispanic, 5% Black, 5% Asian, 4% Native American, and 3% other). Consistent with their unstable self-evaluations, compartmentalized individuals report greater contingencies of self-worth and describe their experience of multiple self-aspects as less authentic than do individuals with integrative self-organization. Compartmentalized individuals also make global self-evaluations more slowly than do integrative individuals. Together with previous findings on self-clarity, these results suggest that compartmentalized individuals may experience difficulties in how they know the self, whereas individuals with integrative self-organization may display greater continuity and evaluative consistency across self-aspects, with easier access to evaluative self-knowledge. © 2014 Wiley Periodicals, Inc.

Self-Concept Structure and the Quality of Self-Knowledge

PubMed Central

Showers, Carolin J.; Ditzfeld, Christopher P.; Zeigler-Hill, Virgil

2014-01-01

Objective Explores the hidden vulnerability of individuals with compartmentalized self-concept structures by linking research on self-organization to related models of self functioning. Method Across three studies, college students completed self-descriptive card sorts as a measure of self-concept structure and either the Contingencies of Self-Worth Scale; Likert ratings of perceived authenticity of self-aspects; or a response latency measure of self-esteem accessibility. In all, there were 382 participants (247 females; 77% White, 6% Hispanic, 5% Black, 5% Asian, 4% Native American, and 3% Other). Results Consistent with their unstable self-evaluations, compartmentalized individuals report greater contingencies of self-worth and describe their experience of multiple self-aspects as less authentic than do individuals with integrative self-organization. Compartmentalized individuals also make global self-evaluations more slowly than do integrative individuals. Conclusions Together with previous findings on self-clarity, these results suggest that compartmentalized individuals may experience difficulties in how they know the self, whereas individuals with integrative self-organization may display greater continuity and evaluative consistency across self-aspects, with easier access to evaluative self-knowledge. PMID:25180616

Figure-ground organization and object recognition processes: an interactive account.

PubMed

Vecera, S P; O'Reilly, R C

1998-04-01

Traditional bottom-up models of visual processing assume that figure-ground organization precedes object recognition. This assumption seems logically necessary: How can object recognition occur before a region is labeled as figure? However, some behavioral studies find that familiar regions are more likely to be labeled figure than less familiar regions, a problematic finding for bottom-up models. An interactive account is proposed in which figure-ground processes receive top-down input from object representations in a hierarchical system. A graded, interactive computational model is presented that accounts for behavioral results in which familiarity effects are found. The interactive model offers an alternative conception of visual processing to bottom-up models.

Design of high reliability organizations in health care.

PubMed

Carroll, J S; Rudolph, J W

2006-12-01

To improve safety performance, many healthcare organizations have sought to emulate high reliability organizations from industries such as nuclear power, chemical processing, and military operations. We outline high reliability design principles for healthcare organizations including both the formal structures and the informal practices that complement those structures. A stage model of organizational structures and practices, moving from local autonomy to formal controls to open inquiry to deep self-understanding, is used to illustrate typical challenges and design possibilities at each stage. We suggest how organizations can use the concepts and examples presented to increase their capacity to self-design for safety and reliability.

Research on Information Sharing Mechanism of Network Organization Based on Evolutionary Game

NASA Astrophysics Data System (ADS)

Wang, Lin; Liu, Gaozhi

2018-02-01

This article first elaborates the concept and effect of network organization, and the ability to share information is analyzed, secondly introduces the evolutionary game theory, network organization for information sharing all kinds of limitations, establishes the evolutionary game model, analyzes the dynamic evolution of network organization of information sharing, through reasoning and evolution. The network information sharing by the initial state and two sides of the game payoff matrix of excess profits and information is the information sharing of cost and risk sharing are the influence of network organization node information sharing decision.

Universities as Inclusive Learning Organizations for Women?: Considering the Role of Women in Faculty and Leadership Roles in Academe

ERIC Educational Resources Information Center

Gouthro, Patricia; Taber, Nancy; Brazil, Amanda

2018-01-01

Purpose: The purpose of this paper is to explore the concept of the learning organization, first discussed by Senge (1990), to determine if it can work as a model in the higher education sector. Design/methodology/approach: Using a critical feminist framework, this paper assesses the possibilities and challenges of viewing universities as…

Concepts and challenges in quantitative pharmacology and model-based drug development.

PubMed

Zhang, Liping; Pfister, Marc; Meibohm, Bernd

2008-12-01

Model-based drug development (MBDD) has been recognized as a concept to improve the efficiency of drug development. The acceptance of MBDD from regulatory agencies, industry, and academia has been growing, yet today's drug development practice is still distinctly distant from MBDD. This manuscript is aimed at clarifying the concept of MBDD and proposing practical approaches for implementing MBDD in the pharmaceutical industry. The following concepts are defined and distinguished: PK-PD modeling, exposure-response modeling, pharmacometrics, quantitative pharmacology, and MBDD. MBDD is viewed as a paradigm and a mindset in which models constitute the instruments and aims of drug development efforts. MBDD covers the whole spectrum of the drug development process instead of being limited to a certain type of modeling technique or application area. The implementation of MBDD requires pharmaceutical companies to foster innovation and make changes at three levels: (1) to establish mindsets that are willing to get acquainted with MBDD, (2) to align processes that are adaptive to the requirements of MBDD, and (3) to create a closely collaborating organization in which all members play a role in MBDD. Pharmaceutical companies that are able to embrace the changes MBDD poses will likely be able to improve their success rate in drug development, and the beneficiaries will ultimately be the patients in need.

A Study to Determine the Contribution Made by Concept Maps to a Computer Architecture and Organization Course

ERIC Educational Resources Information Center

Aydogan, Tuncay; Ergun, Serap

2016-01-01

Concept mapping is a method of graphical learning that can be beneficial as a study method for concept linking and organization. Concept maps, which provide an elegant, easily understood representation of an expert's domain knowledge, are tools for organizing and representing knowledge. These tools have been used in educational environments to…

Leaving home: how older adults prepare for intensive volunteering.

PubMed

Cheek, Cheryl; Piercy, Kathleen W; Grainger, Sarah

2015-03-01

Using the concepts in the Fogg Behavioral Model, 37 volunteers aged 50 and older described their preparation for intensive volunteering with faith-based organizations. Their multistage preparation process included decision points where respondents needed to choose whether to drop out or continue preparation. Ability was a stronger determinant of serving than motivation, particularly in terms of health and finances. This model can facilitate understanding of the barriers to volunteering and aid organizations in tailoring support at crucial points for potential older volunteers in intensive service. © The Author(s) 2013.

On precursor self-organization upon the microwave vacuum-plasma deposition of submonolayer carbon coatings on silicon (100) crystals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yafarov, R. K., E-mail: pirpc@yandex.ru

Scanning atomic-force and electron microscopies are used to study the self-organization kinetics of nanoscale domains upon the deposition of submonolayer carbon coatings on silicon (100) in the microwave plasma of low-pressure ethanol vapor. Model mechanisms of how silicon-carbon domains are formed are suggested. The mechanisms are based on Langmuir’s model of adsorption from the precursor state and modern concepts of modification of the equilibrium structure of the upper atomic layer in crystalline semiconductors under the influence of external action.

Modelling the ecological niche from functional traits

PubMed Central

Kearney, Michael; Simpson, Stephen J.; Raubenheimer, David; Helmuth, Brian

2010-01-01

The niche concept is central to ecology but is often depicted descriptively through observing associations between organisms and habitats. Here, we argue for the importance of mechanistically modelling niches based on functional traits of organisms and explore the possibilities for achieving this through the integration of three theoretical frameworks: biophysical ecology (BE), the geometric framework for nutrition (GF) and dynamic energy budget (DEB) models. These three frameworks are fundamentally based on the conservation laws of thermodynamics, describing energy and mass balance at the level of the individual and capturing the prodigious predictive power of the concepts of ‘homeostasis’ and ‘evolutionary fitness’. BE and the GF provide mechanistic multi-dimensional depictions of climatic and nutritional niches, respectively, providing a foundation for linking organismal traits (morphology, physiology, behaviour) with habitat characteristics. In turn, they provide driving inputs and cost functions for mass/energy allocation within the individual as determined by DEB models. We show how integration of the three frameworks permits calculation of activity constraints, vital rates (survival, development, growth, reproduction) and ultimately population growth rates and species distributions. When integrated with contemporary niche theory, functional trait niche models hold great promise for tackling major questions in ecology and evolutionary biology. PMID:20921046

Hierarchical Recursive Organization and the Free Energy Principle: From Biological Self-Organization to the Psychoanalytic Mind

PubMed Central

Connolly, Patrick; van Deventer, Vasi

2017-01-01

The present paper argues that a systems theory epistemology (and particularly the notion of hierarchical recursive organization) provides the critical theoretical context within which the significance of Friston's (2010a) Free Energy Principle (FEP) for both evolution and psychoanalysis is best understood. Within this perspective, the FEP occupies a particular level of the hierarchical organization of the organism, which is the level of biological self-organization. This form of biological self-organization is in turn understood as foundational and pervasive to the higher levels of organization of the human organism that are of interest to both neuroscience as well as psychoanalysis. Consequently, central psychoanalytic claims should be restated, in order to be located in their proper place within a hierarchical recursive organization of the (situated) organism. In light of the FEP the realization of the psychoanalytic mind by the brain should be seen in terms of the evolution of different levels of systematic organization where the concepts of psychoanalysis describe a level of hierarchical recursive organization superordinate to that of biological self-organization and the FEP. The implication of this formulation is that while “psychoanalytic” mental processes are fundamentally subject to the FEP, they nonetheless also add their own principles of process over and above that of the FEP. A model found in Grobbelaar (1989) offers a recursive bottom-up description of the self-organization of the psychoanalytic ego as dependent on the organization of language (and affect), which is itself founded upon the tendency toward autopoiesis (self-making) within the organism, which is in turn described as formally similar to the FEP. Meaningful consilience between Grobbelaar's model and the hierarchical recursive description available in Friston's (2010a) theory is described. The paper concludes that the valuable contribution of the FEP to psychoanalysis underscores the necessity of reengagement with the core concepts of psychoanalytic theory, and the usefulness that a systems theory epistemology—particularly hierarchical recursive description—can have for this goal. PMID:29038652

Hierarchical Recursive Organization and the Free Energy Principle: From Biological Self-Organization to the Psychoanalytic Mind.

PubMed

Connolly, Patrick; van Deventer, Vasi

2017-01-01

The present paper argues that a systems theory epistemology (and particularly the notion of hierarchical recursive organization) provides the critical theoretical context within which the significance of Friston's (2010a) Free Energy Principle (FEP) for both evolution and psychoanalysis is best understood. Within this perspective, the FEP occupies a particular level of the hierarchical organization of the organism, which is the level of biological self-organization. This form of biological self-organization is in turn understood as foundational and pervasive to the higher levels of organization of the human organism that are of interest to both neuroscience as well as psychoanalysis. Consequently, central psychoanalytic claims should be restated, in order to be located in their proper place within a hierarchical recursive organization of the (situated) organism. In light of the FEP the realization of the psychoanalytic mind by the brain should be seen in terms of the evolution of different levels of systematic organization where the concepts of psychoanalysis describe a level of hierarchical recursive organization superordinate to that of biological self-organization and the FEP. The implication of this formulation is that while "psychoanalytic" mental processes are fundamentally subject to the FEP, they nonetheless also add their own principles of process over and above that of the FEP. A model found in Grobbelaar (1989) offers a recursive bottom-up description of the self-organization of the psychoanalytic ego as dependent on the organization of language (and affect), which is itself founded upon the tendency toward autopoiesis (self-making) within the organism, which is in turn described as formally similar to the FEP. Meaningful consilience between Grobbelaar's model and the hierarchical recursive description available in Friston's (2010a) theory is described. The paper concludes that the valuable contribution of the FEP to psychoanalysis underscores the necessity of reengagement with the core concepts of psychoanalytic theory, and the usefulness that a systems theory epistemology-particularly hierarchical recursive description-can have for this goal.

Effector biology of plant-associated organisms: concepts and perspectives.

PubMed

Win, J; Chaparro-Garcia, A; Belhaj, K; Saunders, D G O; Yoshida, K; Dong, S; Schornack, S; Zipfel, C; Robatzek, S; Hogenhout, S A; Kamoun, S

2012-01-01

Every plant is closely associated with a variety of living organisms. Therefore, deciphering how plants interact with mutualistic and parasitic organisms is essential for a comprehensive understanding of the biology of plants. The field of plant-biotic interactions has recently coalesced around an integrated model. Major classes of molecular players both from plants and their associated organisms have been revealed. These include cell surface and intracellular immune receptors of plants as well as apoplastic and host-cell-translocated (cytoplasmic) effectors of the invading organism. This article focuses on effectors, molecules secreted by plant-associated organisms that alter plant processes. Effectors have emerged as a central class of molecules in our integrated view of plant-microbe interactions. Their study has significantly contributed to advancing our knowledge of plant hormones, plant development, plant receptors, and epigenetics. Many pathogen effectors are extraordinary examples of biological innovation; they include some of the most remarkable proteins known to function inside plant cells. Here, we review some of the key concepts that have emerged from the study of the effectors of plant-associated organisms. In particular, we focus on how effectors function in plant tissues and discuss future perspectives in the field of effector biology.

Proposal for a Spatial Organization Model in Soil Science (The Example of the European Communities Soil Map).

ERIC Educational Resources Information Center

King, D.; And Others

1994-01-01

Discusses the computational problems of automating paper-based spatial information. A new relational structure for soil science information based on the main conceptual concepts used during conventional cartographic work is proposed. This model is a computerized framework for coherent description of the geographical variability of soils, combined…

Applying Schema Theory to Mass Media Information Processing: Moving toward a Formal Model.

ERIC Educational Resources Information Center

Wicks, Robert H.

Schema theory may be significant in determining if and how news audiences process information. For any given news topic, people have from none to many schemata (cognitive structures that represent organized knowledge about a given concept or type of stimulus abstracted from prior experience) upon which to draw. Models of how schemata are used…

Applicability of the Dual-Factor Model of Mental Health for College Students

ERIC Educational Resources Information Center

Eklund, Katie; Dowdy, Erin; Jones, Camille; Furlong, Michael

2011-01-01

This study explores the utility of a dual-factor model of mental health in which the concepts of mental illness and mental wellness are integrated. Life satisfaction, emotional symptoms, personal adjustment, and clinical symptoms were assessed with a sample of 240 college students. Participants were organized into four groups based on levels of…

Spiraling down the river continuum: stream ecology and the U-shaped curve

Treesearch

Jackson R. Webster

2007-01-01

The spiraling concept provides an explicit approach to modeling the longitudinal linkages within a river continuum. I developed a spiraling-based model for particulate organic C dynamics in the Little Tennessee River to synthesize existing data and to illustrate our current understanding of ecosystem processes in river ecosystems. The Little Tennessee River is a medium...

American Association of University Women: Branch Operations Data Modeling Case

ERIC Educational Resources Information Center

Harris, Ranida B.; Wedel, Thomas L.

2015-01-01

A nationally prominent woman's advocacy organization is featured in this case study. The scenario may be used as a teaching case, an assignment, or a project in systems analysis and design as well as database design classes. Students are required to document the system operations and requirements, apply logical data modeling concepts, and design…

Prototype Wash Water Renovation System Integration with Government-Furnished Wash Fixture

NASA Technical Reports Server (NTRS)

1983-01-01

A total renovation concept for removing objectionable materials from spacecraft wash water to make the water reusable was developed. This concept included ferric chloride pretreatment to coagulate suspended solids such as soap and lint, pressure filtration, and carbon adsorption and ion exchange to remove trace dissolved organics and inorganic salts. A breadboard model which was developed to demonstrate the design adequacy of the various system components and the limits on system capacities and efficiencies.

Features of microscopic pedestrian movement in a panic situation based on cellular automata model

NASA Astrophysics Data System (ADS)

Ibrahim, Najihah; Hassan, Fadratul Hafinaz

2017-10-01

Pedestrian movement is the one of the subset for the crowd management under simulation objective. During panic situation, pedestrian usually will create a microscopic movement that lead towards the self-organization. During self-organizing, the behavioral and physical factors had caused the mass effect on the pedestrian movement. The basic CA model will create a movement path for each pedestrian over a time step. However, due to the factors immerge, the CA model needs some enhancement that will establish a real simulation state. Hence, this concept paper will discuss on the enhanced features of CA model for microscopic pedestrian movement during panic situation for a better pedestrian simulation.

Aqueous organic chemistry in the atmosphere: sources and chemical processing of organic aerosols.

PubMed

McNeill, V Faye

2015-02-03

Over the past decade, it has become clear that aqueous chemical processes occurring in cloud droplets and wet atmospheric particles are an important source of organic atmospheric particulate matter. Reactions of water-soluble volatile (or semivolatile) organic gases (VOCs or SVOCs) in these aqueous media lead to the formation of highly oxidized organic particulate matter (secondary organic aerosol; SOA) and key tracer species, such as organosulfates. These processes are often driven by a combination of anthropogenic and biogenic emissions, and therefore their accurate representation in models is important for effective air quality management. Despite considerable progress, mechanistic understanding of some key aqueous processes is still lacking, and these pathways are incompletely represented in 3D atmospheric chemistry and air quality models. In this article, the concepts, historical context, and current state of the science of aqueous pathways of SOA formation are discussed.

Prototype Mcs Parameterization for Global Climate Models

NASA Astrophysics Data System (ADS)

Moncrieff, M. W.

2017-12-01

Excellent progress has been made with observational, numerical and theoretical studies of MCS processes but the parameterization of those processes remain in a dire state and are missing from GCMs. The perceived complexity of the distribution, type, and intensity of organized precipitation systems has arguably daunted attention and stifled the development of adequate parameterizations. TRMM observations imply links between convective organization and large-scale meteorological features in the tropics and subtropics that are inadequately treated by GCMs. This calls for improved physical-dynamical treatment of organized convection to enable the next-generation of GCMs to reliably address a slew of challenges. The multiscale coherent structure parameterization (MCSP) paradigm is based on the fluid-dynamical concept of coherent structures in turbulent environments. The effects of vertical shear on MCS dynamics implemented as 2nd baroclinic convective heating and convective momentum transport is based on Lagrangian conservation principles, nonlinear dynamical models, and self-similarity. The prototype MCS parameterization, a minimalist proof-of-concept, is applied in the NCAR Community Climate Model, Version 5.5 (CAM 5.5). The MCSP generates convectively coupled tropical waves and large-scale precipitation features notably in the Indo-Pacific warm-pool and Maritime Continent region, a center-of-action for weather and climate variability around the globe.

Computational social network modeling of terrorist recruitment.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berry, Nina M.; Turnley, Jessica Glicken; Smrcka, Julianne D.

2004-10-01

The Seldon terrorist model represents a multi-disciplinary approach to developing organization software for the study of terrorist recruitment and group formation. The need to incorporate aspects of social science added a significant contribution to the vision of the resulting Seldon toolkit. The unique addition of and abstract agent category provided a means for capturing social concepts like cliques, mosque, etc. in a manner that represents their social conceptualization and not simply as a physical or economical institution. This paper provides an overview of the Seldon terrorist model developed to study the formation of cliques, which are used as the majormore » recruitment entity for terrorist organizations.« less

Sociopolitical adjustment among Afghan refugees in Pakistan.

PubMed

Centlivres, P; Centlivres-demont, M

1987-01-01

Although international organizations and Pakistanis expect Afghans to act like true refugees--dependent, obedient, and grateful--Afghans consider themselves as temporary exiles who, in protest against an anti-Islamic government, found temporary refuge in Pakistan; or as soldiers in the holy wars who temporarily use their Islamic neighbor as a base before returning to fight in Afghanistan. Conforming to this concept and to these objectives, the refugees seek to preserve a certain autonomy and to lean towards forms of organization which are derived either from their traditional social structure, or as is more common now, from the ideology of the Islamic movements. One can understand that this situation may cause many misunderstandings, especially with international organizations which finance and supervise aid to the Afghan refugees in Pakistan. As for anthropologists, it is necessary to go beyond known concepts, to relativize familiar models and to act on changes which have come about in the structures and ideology of the Afghan people.

Speaking two "Languages" in America: A semantic space analysis of how presidential candidates and their supporters represent abstract political concepts differently.

PubMed

Li, Ping; Schloss, Benjamin; Follmer, D Jake

2017-10-01

In this article we report a computational semantic analysis of the presidential candidates' speeches in the two major political parties in the USA. In Study One, we modeled the political semantic spaces as a function of party, candidate, and time of election, and findings revealed patterns of differences in the semantic representation of key political concepts and the changing landscapes in which the presidential candidates align or misalign with their parties in terms of the representation and organization of politically central concepts. Our models further showed that the 2016 US presidential nominees had distinct conceptual representations from those of previous election years, and these patterns did not necessarily align with their respective political parties' average representation of the key political concepts. In Study Two, structural equation modeling demonstrated that reported political engagement among voters differentially predicted reported likelihoods of voting for Clinton versus Trump in the 2016 presidential election. Study Three indicated that Republicans and Democrats showed distinct, systematic word association patterns for the same concepts/terms, which could be reliably distinguished using machine learning methods. These studies suggest that given an individual's political beliefs, we can make reliable predictions about how they understand words, and given how an individual understands those same words, we can also predict an individual's political beliefs. Our study provides a bridge between semantic space models and abstract representations of political concepts on the one hand, and the representations of political concepts and citizens' voting behavior on the other.

Model of continual metabolism species for estimating stability of CELSS and natural ecosystems

NASA Astrophysics Data System (ADS)

Bartsev, S. I.

Estimation of stability range of natural and man-made ecosystems is necessary for effective control of them However traditional ecological models usually underestimate stability of real ecosystems It takes place due to the usage of fixed stoichiometry model of metabolism The objective is in creating theoretical and mathematical models for adequate description of both man-made and natural ecological systems A concept of genetically fixed but metabolically flexible species is considered in the paper According to the concept the total flow of matter through ecological system is supported at almost constant level depending on energy income by flexibility of metabolic organization of genetic species It is shown introducing continual metabolism species extends the range of stability making its estimation more adequate to real ecological systems

Antithrombin III in animal models of sepsis and organ failure.

PubMed

Dickneite, G

1998-01-01

Antithrombin III (AT III) is the physiological inhibitor of thrombin and other serine proteases of the clotting cascade. In the development of sepsis, septic shock and organ failure, the plasma levels of AT III decrease considerably, suggesting the concept of a substitution therapy with the inhibitor. A decrease of AT III plasma levels might also be associated with other pathological disorders like trauma, burns, pancreatitis or preclampsia. Activation of coagulation and consumption of AT III is the consequence of a generalized inflammation called SIRS (systemic inflammatory response syndrome). The clotting cascade is also frequently activated after organ transplantation, especially if organs are grafted between different species (xenotransplantation). During the past years AT III has been investigated in numerous corresponding disease models in different animal species which will be reviewed here. The bulk of evidence suggests, that AT III substitution reduces morbidity and mortality in the diseased animals. While gaining more experience with AT III, the concept of substitution therapy to maximal baseline plasma levels (100%) appears to become insufficient. Evidence from clinical and preclinical studies now suggests to adjust the AT III plasma levels to about 200%, i.e., doubling the normal value. During the last few years several authors proposed that AT III might not only be an anti-thrombotic agent, but to have in addition an anti-inflammatory effect.

Core and Off-Core Processes in Systems Engineering

NASA Technical Reports Server (NTRS)

Breidenthal, Julian; Forsberg, Kevin

2010-01-01

An emerging methodology of organizing systems-engineering plans is based on a concept of core and off-core processes or activities. This concept has emerged as a result of recognition of a risk in the traditional representation of systems-engineering plans by a Vee model alone, according to which a large system is decomposed into levels of smaller subsystems, then integrated through levels of increasing scope until the full system is constructed. Actual systems-engineering activity is more complicated, raising the possibility that the staff will become confused in the absence of plans which explain the nature and ordering of work beyond the traditional Vee model.

Development of a thermal storage module using modified anhydrous sodium hydroxide

NASA Technical Reports Server (NTRS)

Rice, R. E.; Rowny, P. E.

1980-01-01

The laboratory scale testing of a modified anhydrous NaOH latent heat storage concept for small solar thermal power systems such as total energy systems utilizing organic Rankine systems is discussed. A diagnostic test on the thermal energy storage module and an investigation of alternative heat transfer fluids and heat exchange concepts are specifically addressed. A previously developed computer simulation model is modified to predict the performance of the module in a solar total energy system environment. In addition, the computer model is expanded to investigate parametrically the incorporation of a second heat exchange inside the module which will vaporize and superheat the Rankine cycle power fluid.

A concept mapping study on organic food consumers in Shanghai, China.

PubMed

Hasimu, Huliyeti; Marchesini, Sergio; Canavari, Maurizio

2017-01-01

Despite some similarities with developed countries, the growth of organic market in China seems to follow a different path. Thus, important questions are how Chinese urban consumers perceive organic food, and what are the main concepts associated to the organic attribute. We aimed at representing in graphic form the network of mental associations with the organic concept. We used an adapted version of the "Brand concept mapping" method to acquire, process, and draw individual concept networks perceived by 50 organic food consumers in Shanghai. We then analyzed the data using network and cluster analysis to create aggregated maps for two distinct groups of consumers. Similarly to their peers in developed countries, Chinese consumers perceive organic food as healthy, safe and expensive. However, organic is not necessarily synonymous with natural produce in China, also due to a translation of the term that conveys the idea of a "technology advanced" product. Organic overlaps with the green food label in terms of image and positioning in the market, since they are easily associated and often confused. The two groups we identified show clear differences in the way the organic concept is associated to other concepts and features. The study provides useful information for practitioners: marketers of organic products in China should invest in communication to emphasize the differences with Green Food products and they should consider the possibility of segmenting organic consumers; Chinese policy makers should consider implementing information campaigns aimed at achieving a better understanding of the features of these quality labels among consumers. For researchers, the study confirms that the BCM method is effective and its integration with network and cluster analysis improves the interpretation of individual and aggregated maps. Copyright © 2016 Elsevier Ltd. All rights reserved.

Development of concept-based physiology lessons for biomedical engineering undergraduate students.

PubMed

Nelson, Regina K; Chesler, Naomi C; Strang, Kevin T

2013-06-01

Physiology is a core requirement in the undergraduate biomedical engineering curriculum. In one or two introductory physiology courses, engineering students must learn physiology sufficiently to support learning in their subsequent engineering courses and careers. As preparation for future learning, physiology instruction centered on concepts may help engineering students to further develop their physiology and biomedical engineering knowledge. Following the Backward Design instructional model, a series of seven concept-based lessons was developed for undergraduate engineering students. These online lessons were created as prerequisite physiology training to prepare students to engage in a collaborative engineering challenge activity. This work is presented as an example of how to convert standard, organ system-based physiology content into concept-based content lessons.

Anatomy and Physiology of Multiscale Modeling and Simulation in Systems Medicine.

PubMed

Mizeranschi, Alexandru; Groen, Derek; Borgdorff, Joris; Hoekstra, Alfons G; Chopard, Bastien; Dubitzky, Werner

2016-01-01

Systems medicine is the application of systems biology concepts, methods, and tools to medical research and practice. It aims to integrate data and knowledge from different disciplines into biomedical models and simulations for the understanding, prevention, cure, and management of complex diseases. Complex diseases arise from the interactions among disease-influencing factors across multiple levels of biological organization from the environment to molecules. To tackle the enormous challenges posed by complex diseases, we need a modeling and simulation framework capable of capturing and integrating information originating from multiple spatiotemporal and organizational scales. Multiscale modeling and simulation in systems medicine is an emerging methodology and discipline that has already demonstrated its potential in becoming this framework. The aim of this chapter is to present some of the main concepts, requirements, and challenges of multiscale modeling and simulation in systems medicine.

Concept mapping: Impact on content and organization of technical writing in science

NASA Astrophysics Data System (ADS)

Conklin, Elaine

The purpose of this quasi-experimental study was to compare the relationship between concept mapping and the content and organization of technical writing of ninth grade biology students. All students in the study completed a prewriting assessment. The experimental group received concept map instruction while the control group performed alternate tasks. After instruction, both groups completed the postwriting assessment and mean differences were compared using the t statistic for independent measures. Additionally, scores on the concept map were correlated to the scores on the postwriting assessment using the Pearson correlation coefficient. Finally, attitudes toward using concept mapping as a prewriting strategy were analyzed using the t statistic for repeated measures. Concept mapping significantly improved the depth of content; however, no statistical significance was detected for organization. Students had a significantly positive change in attitude toward using concept mapping to plan a writing assessment, organize information, and think creatively. The findings indicated concept mapping had a positive effect on the students' abilities to select concepts appropriate to respond to a writing prompt, integrate facts into complete thoughts and ideas, and apply it in novel situations. Concept maps appeared to facilitate learning how to process information and transform it into expository writing. Sustained practice in designing concept maps may influence organization as well as content. Developing a systematic approach to synthesize well-organized and coherent arguments in response to a writing task is an invaluable communication skill that has implications for the learner across disciplines and prepares them for higher education and the workforce.

Design of high reliability organizations in health care

PubMed Central

Carroll, J S; Rudolph, J W

2006-01-01

To improve safety performance, many healthcare organizations have sought to emulate high reliability organizations from industries such as nuclear power, chemical processing, and military operations. We outline high reliability design principles for healthcare organizations including both the formal structures and the informal practices that complement those structures. A stage model of organizational structures and practices, moving from local autonomy to formal controls to open inquiry to deep self‐understanding, is used to illustrate typical challenges and design possibilities at each stage. We suggest how organizations can use the concepts and examples presented to increase their capacity to self‐design for safety and reliability. PMID:17142607

Modeling Exponential Population Growth

ERIC Educational Resources Information Center

McCormick, Bonnie

2009-01-01

The concept of population growth patterns is a key component of understanding evolution by natural selection and population dynamics in ecosystems. The National Science Education Standards (NSES) include standards related to population growth in sections on biological evolution, interdependence of organisms, and science in personal and social…

TQM: the essential concepts.

PubMed

Chambers, D W

1998-01-01

This is an introduction to the major concepts in total quality management, a loose collection of management approaches that focus on continuous improvement of processes, guided by routine data collection and adjustment of the processes. Customer focus and involvement of all members of an organization are also characteristics commonly found in TQM. The seventy-five-year history of the movement is sketched from its beginning in statistical work on quality assurance through the many improvements and redefinitions added by American and Japanese thinkers. Essential concepts covered include: control cycles, focus on the process rather than the defects, the GEAR model, importance of the customer, upstream quality, just-in-time, kaizen, and service quality.

Why Has the Health-Promoting Prison Concept Failed to Translate to the United States?

PubMed

Woodall, James

2018-05-01

Two decades since the World Health Organization Regional Office for Europe published a report on health promotion in prison that stimulated further debate on the concept of the "health-promoting prison," this article discusses the extent to which the concept has translated to the United States. One predicted indicator of success for the health-promoting prison movement was the expansion of activity beyond European borders; yet 2 decades since the European model was put forward, there has been very limited activity in the United States. This "Critical Issues and Trends" article suggests reasons why this translation has failed to occur.

[Generation of functional organs from pluripotent stem cells].

PubMed

Miyamoto, Tatsuyuki; Nakauchi, Hiromitsu

2015-10-01

Hematopoietic stem cells (HSCs) have played a major role in stem cell biology, providing many conceptual ideas and models. Among them is the concept of the "niche", a special bone-marrow microenvironment that by exchanging cues regulates stem-cell fate. The HSC niche also plays an important role in HSC transplantation. Successful engraftment of donor HSCs depends on myeloablative pretreatment to empty the niche. The concept of the stem-cell niche has now been extended to the generation of organs. We postulated that an empty "organ niche" exists in a developing animal when development of an organ is genetically disabled. This organ niche should be developmentally compensated by blastocyst complementation using wild-type primary stem cells (PSCs). We proved the principle of organogenesis from xenogeneic PSCs in an embryo unable to form a specific organ, demonstrating the generation of functionally normal rat pancreas by injecting rat PSCs into pancreatogenesis-disabled mouse embryos. This principle has held in pigs. When pancreatogenesis-disabled pig embryos underwent complementation with blastomeres from wild-type pig embryos to produce chimeric pigs, the chimeras had normal pancreata and survived to adulthood. Demonstration of the generation of a functional organ from PSCs in pigs is a very important step toward generation of human cells, tissues, and organs from individual patients' own PSCs in large animals.

The psychology and physiology of temperament: pragmatism in context.

PubMed

Bordogna, F

2001-01-01

This paper traces William James's famous "temperament thesis" according to which the philosophical stance that individuals take depends on their "temperaments." It seeks to understand James's conception of temperament by locating James within a set of contemporary investigations that linked the sources of mental, and even higher, intellectual processes to the physiological and organic constitution of the individual. The paper argues that James understood temperament along the reflex-arc model and discusses the implications of that physiological account of temperament for James's overall conception of philosophy.

A Behavior Analysis of Individuals' Use of the Fairness Heuristic when Interacting with Groups and Organizations

ERIC Educational Resources Information Center

Goltz, Sonia M.

2013-01-01

In the present analysis the author utilizes the groups as patches model (Goltz, 2009, 2010) to extend fairness heuristic theory (Lind, 2001) in which the concept of fairness is thought to be a heuristic that allows individuals to match responses to consequences they receive from groups. In this model, individuals who are reviewing possible groups…

Complexity in Soil Systems: What Does It Mean and How Should We Proceed?

NASA Astrophysics Data System (ADS)

Faybishenko, B.; Molz, F. J.; Brodie, E.; Hubbard, S. S.

2015-12-01

The complex soil systems approach is needed fundamentally for the development of integrated, interdisciplinary methods to measure and quantify the physical, chemical and biological processes taking place in soil, and to determine the role of fine-scale heterogeneities. This presentation is aimed at a review of the concepts and observations concerning complexity and complex systems theory, including terminology, emergent complexity and simplicity, self-organization and a general approach to the study of complex systems using the Weaver (1948) concept of "organized complexity." These concepts are used to provide understanding of complex soil systems, and to develop experimental and mathematical approaches to soil microbiological processes. The results of numerical simulations, observations and experiments are presented that indicate the presence of deterministic chaotic dynamics in soil microbial systems. So what are the implications for the scientists who wish to develop mathematical models in the area of organized complexity or to perform experiments to help clarify an aspect of an organized complex system? The modelers have to deal with coupled systems having at least three dependent variables, and they have to forgo making linear approximations to nonlinear phenomena. The analogous rule for experimentalists is that they need to perform experiments that involve measurement of at least three interacting entities (variables depending on time, space, and each other). These entities could be microbes in soil penetrated by roots. If a process being studied in a soil affects the soil properties, like biofilm formation, then this effect has to be measured and included. The mathematical implications of this viewpoint are examined, and results of numerical solutions to a system of equations demonstrating deterministic chaotic behavior are also discussed using time series and the 3D strange attractors.

Modeling habits as self-sustaining patterns of sensorimotor behavior

PubMed Central

Egbert, Matthew D.; Barandiaran, Xabier E.

2014-01-01

In the recent history of psychology and cognitive neuroscience, the notion of habit has been reduced to a stimulus-triggered response probability correlation. In this paper we use a computational model to present an alternative theoretical view (with some philosophical implications), where habits are seen as self-maintaining patterns of behavior that share properties in common with self-maintaining biological processes, and that inhabit a complex ecological context, including the presence and influence of other habits. Far from mechanical automatisms, this organismic and self-organizing concept of habit can overcome the dominating atomistic and statistical conceptions, and the high temporal resolution effects of situatedness, embodiment and sensorimotor loops emerge as playing a more central, subtle and complex role in the organization of behavior. The model is based on a novel “iterant deformable sensorimotor medium (IDSM),” designed such that trajectories taken through sensorimotor-space increase the likelihood that in the future, similar trajectories will be taken. We couple the IDSM to sensors and motors of a simulated robot, and show that under certain conditions, the IDSM conditions, the IDSM forms self-maintaining patterns of activity that operate across the IDSM, the robot's body, and the environment. We present various environments and the resulting habits that form in them. The model acts as an abstraction of habits at a much needed sensorimotor “meso-scale” between microscopic neuron-based models and macroscopic descriptions of behavior. Finally, we discuss how this model and extensions of it can help us understand aspects of behavioral self-organization, historicity and autonomy that remain out of the scope of contemporary representationalist frameworks. PMID:25152724

Extended probit mortality model for zooplankton against transient change of PCO(2).

PubMed

Sato, Toru; Watanabe, Yuji; Toyota, Koji; Ishizaka, Joji

2005-09-01

The direct injection of CO(2) in the deep ocean is a promising way to mitigate global warming. One of the uncertainties in this method, however, is its impact on marine organisms in the near field. Since the concentration of CO(2), which organisms experience in the ocean, changes with time, it is required to develop a biological impact model for the organisms against the unsteady change of CO(2) concentration. In general, the LC(50) concept is widely applied for testing a toxic agent for the acute mortality. Here, we regard the probit-transformed mortality as a linear function not only of the concentration of CO(2) but also of exposure time. A simple mathematical transform of the function gives a damage-accumulation mortality model for zooplankton. In this article, this model was validated by the mortality test of Metamphiascopsis hirsutus against the transient change of CO(2) concentration.

Expanding on Successful Concepts, Models, and Organization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Teeguarden, Justin G.; Tan, Yu-Mei; Edwards, Stephen W.

In her letter to the editor1 regarding our recent Feature Article “Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework” 2, Dr. von Göetz expressed several concerns about terminology, and the perception that we propose the replacement of successful approaches and models for exposure assessment with a concept. We are glad to have the opportunity to address these issues here. If the goal of the AEP framework was to replace existing exposure models or databases for organizing exposure data with a concept, we would share Dr. von Göetz concerns. Instead,more » the outcome we promote is broader use of an organizational framework for exposure science. The framework would support improved generation, organization, and interpretation of data as well as modeling and prediction, not replacement of models. The field of toxicology has seen the benefits of wide use of one or more organizational frameworks (e.g., mode and mechanism of action, adverse outcome pathway). These frameworks influence how experiments are designed, data are collected, curated, stored and interpreted and ultimately how data are used in risk assessment. Exposure science is poised to similarly benefit from broader use of a parallel organizational framework, which Dr. von Göetz correctly points out, is currently used in the exposure modeling community. In our view, the concepts used so effectively in the exposure modeling community, expanded upon in the AEP framework, could see wider adoption by the field as a whole. The value of such a framework was recognized by the National Academy of Sciences.3 Replacement of models, databases, or any application with the AEP framework was not proposed in our article. The positive role broader more consistent use of such a framework might have in enabling and advancing “general activities such as data acquisition, organization…,” and exposure modeling was discussed in some detail. Like Dr. von Göetz, we recognized the challenges associated with acceptance of the terminology, definitions, and structure proposed in the paper. To address these challenges, an expert workshop was held in May, 2016 to consider and revise the “basic elements” outlined in the paper. The attendees produced revisions to the terminology (e.g., key events) that align with terminology currently in use in the field. We were also careful in our paper to acknowledge a point raised by Dr. von Göetz, that the term AEP implies aggregation, providing these clarifications: “The simplest form of an AEP represents a single source and a single pathway and may more commonly be referred to as an exposure pathway,”; and “An aggregate exposure pathway may represent multiple sources and transfer through single pathways to the TSE, single sources and transfer through multiple pathways to the target site exposure (TSE), or any combination of these.” These clarifications address the concern that the AEP term is not accurate or logical, and further expands upon the word “aggregate” in a broader context. Our use of AEP is consistent with the definition for “aggregate exposure”, which refers to the combined exposures to a single chemical across multiple routes and pathways.3 The AEP framework embraces existing methods for collection, prediction, organization, and interpretation of human and ecological exposure data cited by Dr. von Göetz. We remain hopeful that wider recognition and use of an organizing concept for exposure information across the exposure science, toxicology and epidemiology communities advances the development of the kind of infrastructure and models Dr. von Göetz discusses. This outcome would be a step forward, rather than a step backward.« less

Software Engineering Program: Software Process Improvement Guidebook

NASA Technical Reports Server (NTRS)

1996-01-01

The purpose of this document is to provide experience-based guidance in implementing a software process improvement program in any NASA software development or maintenance community. This guidebook details how to define, operate, and implement a working software process improvement program. It describes the concept of the software process improvement program and its basic organizational components. It then describes the structure, organization, and operation of the software process improvement program, illustrating all these concepts with specific NASA examples. The information presented in the document is derived from the experiences of several NASA software organizations, including the SEL, the SEAL, and the SORCE. Their experiences reflect many of the elements of software process improvement within NASA. This guidebook presents lessons learned in a form usable by anyone considering establishing a software process improvement program within his or her own environment. This guidebook attempts to balance general and detailed information. It provides material general enough to be usable by NASA organizations whose characteristics do not directly match those of the sources of the information and models presented herein. It also keeps the ideas sufficiently close to the sources of the practical experiences that have generated the models and information.

Proceedings of the Introducing Requirements Management into Organizations Workshop: Requirements Management Transition Packages November 11-13, 1996.

DTIC Science & Technology

1997-04-25

the community, as with the Systems Engineering Capability Maturity Model ? • Should it be built by a small working group ? • What role should... collaborating on the development of the transition package concept for requirements management with two organizations. When participants in the workshop...34 learning " and approaches it as a qualitative activity among qualified peers [Spendolini 92]. In the spirit of this style of

What Restructuring Is: In Search of a Definition.

ERIC Educational Resources Information Center

Harvey, Glen; Crandall, David P.

Educational restructuring, an emerging concept without a single definition or a definitive model, supports the notion of multiple alternatives. Typical school improvement and excellence initiatives do not, by themselves, constitute restructuring. Restructuring means that schools should be organized according to children's learning needs. To…

Theories of Levels in Organizational Science.

ERIC Educational Resources Information Center

Rousseau, Denise M.

This paper presents concepts and principles pertinent to the development of cross-level and multilevel theory in organizational science by addressing a number of fundamental theoretical issues. It describes hierarchy theory, systems theory, and mixed-level models of organization developed by organizational scientists. Hierarchy theory derives from…

Integrating plant litter quality, soil organic matter stabilization, and the carbon saturation concept.

PubMed

Castellano, Michael J; Mueller, Kevin E; Olk, Daniel C; Sawyer, John E; Six, Johan

2015-09-01

Labile, 'high-quality', plant litters are hypothesized to promote soil organic matter (SOM) stabilization in mineral soil fractions that are physicochemically protected from rapid mineralization. However, the effect of litter quality on SOM stabilization is inconsistent. High-quality litters, characterized by high N concentrations, low C/N ratios, and low phenol/lignin concentrations, are not consistently stabilized in SOM with greater efficiency than 'low-quality' litters characterized by low N concentrations, high C/N ratios, and high phenol/lignin concentrations. Here, we attempt to resolve these inconsistent results by developing a new conceptual model that links litter quality to the soil C saturation concept. Our model builds on the Microbial Efficiency-Matrix Stabilization framework (Cotrufo et al., 2013) by suggesting the effect of litter quality on SOM stabilization is modulated by the extent of soil C saturation such that high-quality litters are not always stabilized in SOM with greater efficiency than low-quality litters. © 2015 John Wiley & Sons Ltd.

Reporting intellectual capital in health care organizations: specifics, lessons learned, and future research perspectives.

PubMed

Veltri, Stefania; Bronzetti, Giovanni; Sicoli, Graziella

2011-01-01

This article analyzes the concept of intellectual capital (IC) in the health sector sphere by studying the case of a major nonprofit research organization in this sector, which has for some time been publishing IC reports. In the last few years, health care organizations have been the object of great attention in the implementation and transfer of managerial models and tools; however, there is still a lack of attention paid to the strategic management of IC as a fundamental resource for supporting and enhancing performance improvement dynamics. The main aim of this article is to examine the IC reporting model used by the Center of Molecular Medicine (CMM), a Swedish health organization which is an outstanding benchmark in reporting its IC. We also consider the specifics of IC reporting for health organizations, the lessons learned by analyzing CMM's IC reporting, and future perspectives for research.

Evaluating the granularity balance of hierarchical relationships within large biomedical terminologies towards quality improvement.

PubMed

Luo, Lingyun; Tong, Ling; Zhou, Xiaoxi; Mejino, Jose L V; Ouyang, Chunping; Liu, Yongbin

2017-11-01

Organizing the descendants of a concept under a particular semantic relationship may be rather arbitrarily carried out during the manual creation processes of large biomedical terminologies, resulting in imbalances in relationship granularity. This work aims to propose scalable models towards systematically evaluating the granularity balance of semantic relationships. We first utilize "parallel concepts set (PCS)" and two features (the length and the strength) of the paths between PCSs to design the general evaluation models, based on which we propose eight concrete evaluation models generated by two specific types of PCSs: single concept set and symmetric concepts set. We then apply those concrete models to the IS-A relationship in FMA and SNOMED CT's Body Structure subset, as well as to the Part-Of relationship in FMA. Moreover, without loss of generality, we conduct two additional rounds of applications on the Part-Of relationship after removing length redundancies and strength redundancies sequentially. At last, we perform automatic evaluation on the imbalances detected after the final round for identifying missing concepts, misaligned relations and inconsistencies. For the IS-A relationship, 34 missing concepts, 80 misalignments and 18 redundancies in FMA as well as 28 missing concepts, 114 misalignments and 1 redundancy in SNOMED CT were uncovered. In addition, 6,801 instances of imbalances for the Part-Of relationship in FMA were also identified, including 3,246 redundancies. After removing those redundancies from FMA, the total number of Part-Of imbalances was dramatically reduced to 327, including 51 missing concepts, 294 misaligned relations, and 36 inconsistencies. Manual curation performed by the FMA project leader confirmed the effectiveness of our method in identifying curation errors. In conclusion, the granularity balance of hierarchical semantic relationship is a valuable property to check for ontology quality assurance, and the scalable evaluation models proposed in this study are effective in fulfilling this task, especially in auditing relationships with sub-hierarchies, such as the seldom evaluated Part-Of relationship. Copyright © 2017 Elsevier Inc. All rights reserved.

The TEF modeling and analysis approach to advance thermionic space power technology

NASA Astrophysics Data System (ADS)

Marshall, Albert C.

1997-01-01

Thermionics space power systems have been proposed as advanced power sources for future space missions that require electrical power levels significantly above the capabilities of current space power systems. The Defense Special Weapons Agency's (DSWA) Thermionic Evaluation Facility (TEF) is carrying out both experimental and analytical research to advance thermionic space power technology to meet this expected need. A Modeling and Analysis (M&A) project has been created at the TEF to develop analysis tools, evaluate concepts, and guide research. M&A activities are closely linked to the TEF experimental program, providing experiment support and using experimental data to validate models. A planning exercise has been completed for the M&A project, and a strategy for implementation was developed. All M&A activities will build on a framework provided by a system performance model for a baseline Thermionic Fuel Element (TFE) concept. The system model is composed of sub-models for each of the system components and sub-systems. Additional thermionic component options and model improvements will continue to be incorporated in the basic system model during the course of the program. All tasks are organized into four focus areas: 1) system models, 2) thermionic research, 3) alternative concepts, and 4) documentation and integration. The M&A project will provide a solid framework for future thermionic system development.

A New Look at Preservice Teachers' Conceptions of Classroom Management and Organization: Uncovering Complexity and Dissonance

ERIC Educational Resources Information Center

Kaufman, Douglas; Moss, David M.

2010-01-01

This article examines preservice teachers' conceptions of classroom management and organization in light of their training and beliefs about good teaching. Students in their final year of a 5-year program discussed their definitions and conceptions of classroom management, organization, and rule systems through an open-ended questionnaire.…

Organic Chemistry Students' Fragmented Ideas about the Structure and Function of Nucleophiles and Electrophiles: A Concept Map Analysis

ERIC Educational Resources Information Center

Anzovino, Mary E.; Bretz, Stacey Lowery

2016-01-01

Organic chemistry students struggle with multiple aspects of reaction mechanisms and the curved arrow notation used by organic chemists. Many faculty believe that an understanding of nucleophiles and electrophiles, among other concepts, is required before students can develop fluency with the electronpushing formalism (EPF). An expert concept map…

Defining a 21st Century Air Force (Services) Business Model

DTIC Science & Technology

2014-05-10

activity business model. The benefit of sequestration drives efficiencies. However, the Services, Manpower, and Personnel career field has... benefits of the PPV model is government investment costs are very low. While there are times when the host organization may "chip in" a small amount...with a desired concept or brand. The bulk of the funding (usually 75 percent or more) is provided by the brand operator, franchisee or parent

Systems view on spatial planning and perception based on invariants in agent-environment dynamics

PubMed Central

Mettler, Bérénice; Kong, Zhaodan; Li, Bin; Andersh, Jonathan

2015-01-01

Modeling agile and versatile spatial behavior remains a challenging task, due to the intricate coupling of planning, control, and perceptual processes. Previous results have shown that humans plan and organize their guidance behavior by exploiting patterns in the interactions between agent or organism and the environment. These patterns, described under the concept of Interaction Patterns (IPs), capture invariants arising from equivalences and symmetries in the interaction with the environment, as well as effects arising from intrinsic properties of human control and guidance processes, such as perceptual guidance mechanisms. The paper takes a systems' perspective, considering the IP as a unit of organization, and builds on its properties to present a hierarchical model that delineates the planning, control, and perceptual processes and their integration. The model's planning process is further elaborated by showing that the IP can be abstracted, using spatial time-to-go functions. The perceptual processes are elaborated from the hierarchical model. The paper provides experimental support for the model's ability to predict the spatial organization of behavior and the perceptual processes. PMID:25628524

Numeric and symbolic knowledge representation of cerebral cortex anatomy: methods and preliminary results.

PubMed

Dameron, O; Gibaud, B; Morandi, X

2004-06-01

The human cerebral cortex anatomy describes the brain organization at the scale of gyri and sulci. It is used as landmarks for neurosurgery as well as localization support for functional data analysis or inter-subject data comparison. Existing models of the cortex anatomy either rely on image labeling but fail to represent variability and structural properties or rely on a conceptual model but miss the inner 3D nature and relations of anatomical structures. This study was therefore conducted to propose a model of sulco-gyral anatomy for the healthy human brain. We hypothesized that both numeric knowledge (i.e., image-based) and symbolic knowledge (i.e., concept-based) have to be represented and coordinated. In addition, the representation of this knowledge should be application-independent in order to be usable in various contexts. Therefore, we devised a symbolic model describing specialization, composition and spatial organization of cortical anatomical structures. We also collected numeric knowledge such as 3D models of shape and shape variation about cortical anatomical structures. For each numeric piece of knowledge, a companion file describes the concept it refers to and the nature of the relationship. Demonstration software performs a mapping between the numeric and the symbolic aspects for browsing the knowledge base.

Using Implementation and Dissemination Concepts to Spread 21st-century Well-Child Care at a Health Maintenance Organization

PubMed Central

Beck, Arne; Bergman, David A; Rahm, Alanna K; Dearing, James W; Glasgow, Russell E

2009-01-01

We describe here the use of a conceptual framework for implementing and disseminating in a Health Maintenance Organization an evidence-based model of well-child care (WCC) that includes developmental and preventive services recommended by the American Academy of Pediatrics. Twenty-first Century WCC is a parent-centered, team-based, primary care model that combines online previsit assessments—completed by parents and caregivers regarding clinic-based weight, growth, and development assessments—with vaccinations and anticipatory guidance. Nurses, nurse practitioners, developmental specialists, and pediatricians all play roles in the WCC model. Patient and clinician interaction, health records, and resources are all facilitated through a Web-based diagnostic, management, tracking, and resource information tool. Implementation and dissemination concepts and their attendant practices and tools can reliably be used to augment strategic decisions about how to best disseminate and implement innovations in health care delivery. Unlike innovations that are embedded only in technical systems, validated models of team-based health care have multiple components that must be made compatible with complex sociotechnical systems. Interpersonal communication, work, coordination, and judgment are key processes that affect implementation quality. Implementation can involve tailoring to a particular site and customizing either the model or the organizational context to accommodate it. PMID:20740083

Optimizing health care delivery by integrating workplaces, homes, and communities: how occupational and environmental medicine can serve as a vital connecting link between accountable care organizations and the patient-centered medical home.

PubMed

McLellan, Robert K; Sherman, Bruce; Loeppke, Ronald R; McKenzie, Judith; Mueller, Kathryn L; Yarborough, Charles M; Grundy, Paul; Allen, Harris; Larson, Paul W

2012-04-01

In recent years, the health care reform discussion in the United States has focused increasingly on the dual goals of cost-effective delivery and better patient outcomes. A number of new conceptual models for health care have been advanced to achieve these goals, including two that are well along in terms of practical development and implementation-the patient-centered medical home (PCMH) and accountable care organizations (ACOs). At the core of these two emerging concepts is a new emphasis on encouraging physicians, hospitals, and other health care stakeholders to work more closely together to better coordinate patient care through integrated goals and data sharing and to create team-based approaches that give a greater role to patients in health care decision-making. This approach aims to achieve better health outcomes at lower cost. The PCMH model emphasizes the central role of primary care and facilitation of partnerships between patient, physician, family, and other caregivers, and integrates this care along a spectrum that includes hospitals, specialty care, and nursing homes. Accountable care organizations make physicians and hospitals more accountable in the care system, emphasizing organizational integration and efficiencies coupled with outcome-oriented, performance-based medical strategies to improve the health of populations. The ACO model is meant to improve the value of health care services, controlling costs while improving quality as defined by outcomes, safety, and patient experience. This document urges adoption of the PCMH model and ACOs, but argues that in order for these new paradigms to succeed in the long term, all sectors with a stake in health care will need to become better aligned with them-including the employer community, which remains heavily invested in the health outcomes of millions of Americans. At present, ACOs are largely being developed as a part of the Medicare and Medicaid systems, and the PCMH model is still gathering momentum and evolving among physicians. But, the potential exists for implementation of both of these concepts across a much broader community of patients. By extending the well-conceived integrative concepts of the PCMH model and ACOs into the workforce via occupational and environmental medicine (OEM) physicians, the power of these concepts would be significantly enhanced. Occupational and environmental medicine provides a well-established infrastructure and parallel strategies that could serve as a force multiplier in achieving the fundamental goals of the PCMH model and ACOs. In this paradigm, the workplace-where millions of Americans spend a major portion of their daily lives-becomes an essential element, next to communities and homes, in an integrated system of health anchored by the PCMH and ACO concepts. To be successful, OEM physicians will need to think and work innovatively about how they can provide today's employer health services-ranging from primary care and preventive care to workers' compensation and disability management-within tomorrow's PCMH and ACO models.

Rule-following as an Anticipatory Act: Interaction in Second Person and an Internal Measurement Model of Dialogue

NASA Astrophysics Data System (ADS)

Takahashi, Tatsuji; Gunji, Yukio-Pegio

2008-10-01

We pursue anticipation in second person or normative anticipation. As the first step, we make the three concepts second person, internal measurement and asynchroneity clearer by introducing the velocity of logic νl and the velocity of communication νc, in the context of social communication. After proving anticipatory nature of rule-following or language use in general via Kripke's "rule-following paradox," we present a mathematical model expressing the internality essential to second person, taking advantage of equivalences and differences in the formal language theory. As a consequence, we show some advantages of negatively considered concepts and arguments by concretizing them into an elementary and explicit formal model. The time development of the model shows a self-organizing property which never results if we adopt a third person stance.

[Mathematic concept model of accumulation of functional disorders associated with environmental factors].

PubMed

Zaĭtseva, N V; Trusov, P V; Kir'ianov, D A

2012-01-01

The mathematic concept model presented describes accumulation of functional disorders associated with environmental factors, plays predictive role and is designed for assessments of possible effects caused by heterogenous factors with variable exposures. Considering exposure changes with self-restoration process opens prospects of using the model to evaluate, analyse and manage occupational risks. To develop current theoretic approaches, the authors suggested a model considering age-related body peculiarities, systemic interactions of organs, including neuro-humoral regulation, accumulation of functional disorders due to external factors, rehabilitation of functions during treatment. General objective setting covers defining over a hundred unknow coefficients that characterize speed of various processes within the body. To solve this problem, the authors used iteration approach, successive identification, that starts from the certain primary approximation of the model parameters and processes subsequent updating on the basis of new theoretic and empirical knowledge.

Ocean feature recognition using genetic algorithms with fuzzy fitness functions (GA/F3)

NASA Technical Reports Server (NTRS)

Ankenbrandt, C. A.; Buckles, B. P.; Petry, F. E.; Lybanon, M.

1990-01-01

A model for genetic algorithms with semantic nets is derived for which the relationships between concepts is depicted as a semantic net. An organism represents the manner in which objects in a scene are attached to concepts in the net. Predicates between object pairs are continuous valued truth functions in the form of an inverse exponential function (e sub beta lxl). 1:n relationships are combined via the fuzzy OR (Max (...)). Finally, predicates between pairs of concepts are resolved by taking the average of the combined predicate values of the objects attached to the concept at the tail of the arc representing the predicate in the semantic net. The method is illustrated by applying it to the identification of oceanic features in the North Atlantic.

Automation in organizations: Eternal conflict

NASA Technical Reports Server (NTRS)

Dieterly, D. L.

1981-01-01

Some ideas on and insights into the problems associated with automation in organizations are presented with emphasis on the concept of automation, its relationship to the individual, and its impact on system performance. An analogy is drawn, based on an American folk hero, to emphasize the extent of the problems encountered when dealing with automation within an organization. A model is proposed to focus attention on a set of appropriate dimensions. The function allocation process becomes a prominent aspect of the model. The current state of automation research is mentioned in relation to the ideas introduced. Proposed directions for an improved understanding of automation's effect on the individual's efficiency are discussed. The importance of understanding the individual's perception of the system in terms of the degree of automation is highlighted.

TOPAZ II Anti-Criticality Device Rapid Prototype

NASA Astrophysics Data System (ADS)

Campbell, Donald R.; Otting, William D.

1994-07-01

The Ballistic Missile Defense Organization (BMDO) has been working on a Nuclear Electric Propulsion Space Test Project (NEPSTP) using an existing Russian Topaz II reactor system to power the NEPSTP satellite. Safety investigations have shown that it will be possible to safely launch the Topaz II system in the United States with some modification to preclude water flooded criticality. A ``fuel-out'' water subcriticality concept was selected by the Los Alamos National Laboratory (LANL) as the baseline concept. A fuel-out anti-criticality device (ACD) conceptual design was developed by Rockwell. The concept functions to hold the fuel from the four centermost thermionic fuel elements (TFEs) outside the reactor during launch and reliably inserts the fuel into the reactor once the operational orbit is achieved. A four-tenths scale ACD rapid prototype model, fabricated from the CATIA solids design model, clearly shows in three dimensions the relative size and spatial relationship of the ACD components.

What constitutes an effective community pharmacy?--development of a preliminary model of organizational effectiveness through concept mapping with multiple stakeholders.

PubMed

Scahill, S L; Harrison, J; Carswell, P

2010-08-01

To develop a multi-constituent model of organizational effectiveness for community pharmacy. Using Concept Systems software, a project with 14 stakeholders included a three stage process: (i) face to face brainstorming to generate statements describing what constitutes an effective community pharmacy, followed by (ii) statement reduction and approval by participants, followed by (iii) sorting of the statements into themes with rating of each statement for importance. Primary care in a government-funded, national health care system. A multi-constituent group representing policy-makers and health care providers including; community pharmacy, professional pharmacy organizations, primary health care funders and policy-makers, general practitioners and general practice support organizations. Statement clusters included: 'has safe and effective workflows', 'contributes to the safe use of medicines', 'manages human resources and has leadership', 'has a community focus', 'is integrated within primary care', 'is a respected innovator', 'provides health promotion and preventative care', 'communicates and advocates'. These clusters fit into a quadrant model setting stakeholder focus against role development. The poles of stakeholder focus are 'internal capacity' and 'social utility'. The poles of role development are labelled 'traditional safety roles' and 'integration and innovation'. Organizational effectiveness in community pharmacy includes the internal and external focus of the organization and role development. Our preliminary model describes an effective community pharmacy and provides a platform for investigation of the factors that may influence the organizational effectiveness of individual community pharmacies now and into the future.

The "proactive" model of learning: Integrative framework for model-free and model-based reinforcement learning utilizing the associative learning-based proactive brain concept.

PubMed

Zsuga, Judit; Biro, Klara; Papp, Csaba; Tajti, Gabor; Gesztelyi, Rudolf

2016-02-01

Reinforcement learning (RL) is a powerful concept underlying forms of associative learning governed by the use of a scalar reward signal, with learning taking place if expectations are violated. RL may be assessed using model-based and model-free approaches. Model-based reinforcement learning involves the amygdala, the hippocampus, and the orbitofrontal cortex (OFC). The model-free system involves the pedunculopontine-tegmental nucleus (PPTgN), the ventral tegmental area (VTA) and the ventral striatum (VS). Based on the functional connectivity of VS, model-free and model based RL systems center on the VS that by integrating model-free signals (received as reward prediction error) and model-based reward related input computes value. Using the concept of reinforcement learning agent we propose that the VS serves as the value function component of the RL agent. Regarding the model utilized for model-based computations we turned to the proactive brain concept, which offers an ubiquitous function for the default network based on its great functional overlap with contextual associative areas. Hence, by means of the default network the brain continuously organizes its environment into context frames enabling the formulation of analogy-based association that are turned into predictions of what to expect. The OFC integrates reward-related information into context frames upon computing reward expectation by compiling stimulus-reward and context-reward information offered by the amygdala and hippocampus, respectively. Furthermore we suggest that the integration of model-based expectations regarding reward into the value signal is further supported by the efferent of the OFC that reach structures canonical for model-free learning (e.g., the PPTgN, VTA, and VS). (c) 2016 APA, all rights reserved).

Cloud Macroscopic Organization: Order Emerging from Randomness

NASA Technical Reports Server (NTRS)

Yuan, Tianle

2011-01-01

Clouds play a central role in many aspects of the climate system and their forms and shapes are remarkably diverse. Appropriate representation of clouds in climate models is a major challenge because cloud processes span at least eight orders of magnitude in spatial scales. Here we show that there exists order in cloud size distribution of low-level clouds, and that it follows a power-law distribution with exponent gamma close to 2. gamma is insensitive to yearly variations in environmental conditions, but has regional variations and land-ocean contrasts. More importantly, we demonstrate this self-organizing behavior of clouds emerges naturally from a complex network model with simple, physical organizing principles: random clumping and merging. We also demonstrate symmetry between clear and cloudy skies in terms of macroscopic organization because of similar fundamental underlying organizing principles. The order in the apparently complex cloud-clear field thus has its root in random local interactions. Studying cloud organization with complex network models is an attractive new approach that has wide applications in climate science. We also propose a concept of cloud statistic mechanics approach. This approach is fully complementary to deterministic models, and the two approaches provide a powerful framework to meet the challenge of representing clouds in our climate models when working in tandem.

Organ-on-a-chip platforms for studying drug delivery systems.

PubMed

Bhise, Nupura S; Ribas, João; Manoharan, Vijayan; Zhang, Yu Shrike; Polini, Alessandro; Massa, Solange; Dokmeci, Mehmet R; Khademhosseini, Ali

2014-09-28

Novel microfluidic tools allow new ways to manufacture and test drug delivery systems. Organ-on-a-chip systems - microscale recapitulations of complex organ functions - promise to improve the drug development pipeline. This review highlights the importance of integrating microfluidic networks with 3D tissue engineered models to create organ-on-a-chip platforms, able to meet the demand of creating robust preclinical screening models. Specific examples are cited to demonstrate the use of these systems for studying the performance of drug delivery vectors and thereby reduce the discrepancies between their performance at preclinical and clinical trials. We also highlight the future directions that need to be pursued by the research community for these proof-of-concept studies to achieve the goal of accelerating clinical translation of drug delivery nanoparticles. Copyright © 2014 Elsevier B.V. All rights reserved.

Quantifying long-term trajectories of plant community change with movement models: implication for ecological resilience

USDA-ARS?s Scientific Manuscript database

Quantification of rates and patterns of community dynamics is central for understanding the organization and function of ecosystems. These insights may support a greater empirical understanding of ecological resilience, and the application of resilience concepts toward ecosystem management. Distinct...

Environmental Education & Communication for a Sustainable World: Handbook for International Practitioners.

ERIC Educational Resources Information Center

Day, Brian A., Ed.; Monroe, Martha C., Ed.

This document targets organizations and practitioners developing an environmental education or communication project. The manual presents case studies to share experiences, information, and models of working in education. There are 15 chapters in 4 sections. Section One entitled "Fundamental Concepts in Environmental Education and…

Situational Favorability and Perceived Environmental Uncertainty: An Integrative Approach

ERIC Educational Resources Information Center

Nebeker, Delbert M.

1975-01-01

Presents the conceptual and empirical basis for a possible combining of Fiedler's contingency model of leadership effectiveness and Lawrence and Lorsch's contingency organization theory. Using perceived environmental uncertainty as the integrating concept, a measure of decision uncertainty was found to be significantly related to Fiedler's…

Simulation of OSCM Concepts for HQ SACT

DTIC Science & Technology

2007-06-01

effective method for creating understanding, identifying problems and developing solutions. • Simulation of a goal driven organization is a cost...effective method to visualize some aspects of the problem space Toolbox • The team used Extend™, a COTS product from Imagine That!® (http...Nations flow Model OSCM ATARES flow Batching A/C & Pallets Model ISAF Airbridge flow Flying and unbatching A/C Fleet Create resources Calculate flight

H. A. Gleason's 'individualistic concept' and theory of animal communities: a continuing controversy.

PubMed

McIntosh, R P

1995-05-01

A tradition of natural history and of the lore of early twentieth-century ecology was that organisms lived together and interacted to form natural entities or communities. Before there was a recognizable science of ecology, Mobius (1877) had provided a name 'biocoenosis' for such entities. This concept persisted in the early decades of ecological science; at an extreme it was maintained that the community had integrating capabilities and organization like those of an individual organism, hence the term organismic community. In the 1950s-1970s an alternative individualist concept, derived from the ideas of H. A. Gleason (1939), gained credence which held that communities were largely a coincidence of individualistic species characteristics, continuously varying environments and different probabilities of a species arriving on a given site. During the same period, however, a body of population based theory of animal communities became dominant which perpetuated the idea of patterns in nature based on biotic interactions among species resulting in integrated communities. This theory introduced an extended terminology and mathematical models to explain the organization of species into groups of compatible species governed by rules. In the late 1970s the premises and methods of the theory came under attack and a vigorous debate ensued. The alternatives proposed were, at an extreme, null models of random aggregations of species or stochastic, individualistic aggregations of species, sensu Gleason. Extended research and debate ensued during the 1980s resulting in an explosion of studies of animal communities and a plethora of symposia and volumes of collected works concerning the nature of animal communities. The inherent complexity of communities and the traditional differences among animal ecologists about how they should be defined and delimited, at what scale of taxa, space and time to study them, and appropriate methods of study and analysis have resulted in extended and as yet inconclusive discussions. Recent differences and discussions are considered under five general categories, evolution and community theory, individualistic concept, community definition, questions from community ecology and empirical studies. Communities are seen by some ecologists as entities of coevolving species and, in any case, it is necessary to integrate evolutionary ideas with the varied concepts of community.(ABSTRACT TRUNCATED AT 400 WORDS)

Building HR capability in health care organizations.

PubMed

Khatri, Naresh

2006-01-01

The current human resource (HR) management practices in health care are consistent with the industrial model of management. However, health care organizations are not factories. They are highly knowledge-intensive and service-oriented entities and thus require a different set of HR practices and systems to support them. Drawing from the resource-based theory, I argue that HRs are a potent weapon of competitive advantage for health care organizations and propose a five-dimensional conception of HR capability for harnessing HRs in health care organizations. The significant complementarities that exist between HRs and information technologies for delivering safer and better quality of patient care are also discussed.

Using activity-based costing and theory of constraints to guide continuous improvement in managed care.

PubMed

Roybal, H; Baxendale, S J; Gupta, M

1999-01-01

Activity-based costing and the theory of constraints have been applied successfully in many manufacturing organizations. Recently, those concepts have been applied in service organizations. This article describes the application of activity-based costing and the theory of constraints in a managed care mental health and substance abuse organization. One of the unique aspects of this particular application was the integration of activity-based costing and the theory of constraints to guide process improvement efforts. This article describes the activity-based costing model and the application of the theory of constraint's focusing steps with an emphasis on unused capacities of activities in the organization.

Exploring International Views on Key Concepts for Mass-gathering Health through a Delphi Process.

PubMed

Steenkamp, Malinda; Hutton, Alison E; Ranse, Jamie C; Lund, Adam; Turris, Sheila A; Bowles, Ron; Arbuthnott, Katherine; Arbon, Paul A

2016-08-01

Introduction The science underpinning mass-gathering health (MGH) is developing rapidly. However, MGH terminology and concepts are not yet well defined or used consistently. These variations can complicate comparisons across settings. There is, therefore, a need to develop consensus and standardize concepts and data points to support the development of a robust MGH evidence-base for governments, event planners, responders, and researchers. This project explored the views and sought consensus of international MGH experts on previously published concepts around MGH to inform the development of a transnational minimum data set (MDS) with an accompanying data dictionary (DD). Report A two-round Delphi process was undertaken involving volunteers from the World Health Organization (WHO) Virtual Interdisciplinary Advisory Group (VIAG) on Mass Gatherings (MGs) and the MG section of the World Association for Disaster and Emergency Medicine (WADEM). The first online survey tested agreement on six key concepts: (1) using the term "MG HEALTH;" (2) purposes of the proposed MDS and DD; (3) event phases; (4) two MG population models; (5) a MGH conceptual diagram; and (6) a data matrix for organizing MGH data elements. Consensus was defined as ≥80% agreement. Round 2 presented five refined MGH principles based on Round 1 input that was analyzed using descriptive statistics and content analysis. Thirty-eight participants started Round 1 with 36 completing the survey and 24 (65% of 36) completing Round 2. Agreement was reached on: the term "MGH" (n=35/38; 92%); the stated purposes for the MDS (n=38/38; 100%); the two MG population models (n=31/36; 86% and n=30/36; 83%, respectively); and the event phases (n=34/36; 94%). Consensus was not achieved on the overall conceptual MGH diagram (n=25/37; 67%) and the proposed matrix to organize data elements (n=28/37; 77%). In Round 2, agreement was reached on all the proposed principles and revisions, except on the MGH diagram (n=18/24; 75%). Discussion/Conclusions Event health stakeholders require sound data upon which to build a robust MGH evidence-base. The move towards standardization of data points and/or reporting items of interest will strengthen the development of such an evidence-base from which governments, researchers, clinicians, and event planners could benefit. There is substantial agreement on some broad concepts underlying MGH amongst an international group of MG experts. Refinement is needed regarding an overall conceptual diagram and proposed matrix for organizing data elements. Steenkamp M , Hutton AE , Ranse JC , Lund A , Turris SA , Bowles R , Arbuthnott K , Arbon PA . Exploring international views on key concepts for mass-gathering health through a Delphi process. Prehosp Disaster Med. 2016;31(4):443-453.

Mapping primary health care renewal in South America.

PubMed

Acosta Ramírez, Naydú; Giovanella, Ligia; Vega Romero, Roman; Tejerina Silva, Herland; de Almeida, Patty Fidelis; Ríos, Gilberto; Goede, Hedwig; Oliveira, Suelen

2016-06-01

Primary health care (PHC) renewal processes are currently ongoing in South America (SA), but their characteristics have not been systematically described. The study aimed to describe and contrast the PHC approaches being implemented in SA to provide knowledge of current conceptions, models and challenges. This multiple case study used a qualitative approach with technical visits to health ministries in order to apply key-informant interviews of 129 PHC national policy makers and 53 local managers, as well as field observation of 57 selected PHC providers and document analysis, using a common matrix for data collection and analysis. PHC approaches were analysed by triangulating sources using the following categories: PHC philosophy and conception, service provision organization, intersectoral collaboration and social participation. Primary health care models were identified in association with existing health system types and the dynamics of PHC renewal in each country. A neo-selective model was found in three countries where coverage is segmented by private and public regimes; here, individual and collective care are separated. A comprehensive approach similar to the Alma-Ata model was found in seven countries where the public sector predominates and individual, family and community care are coordinated under the responsibility of the same health care team. The process of implementing a renewed PHC approach is affected by how health systems are funded and organized. Both models face many obstacles. In addition, care system organization, intersectoral coordination and social participation are weak in most of the countries. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

The Semantic Learning Organization

ERIC Educational Resources Information Center

Sicilia, Miguel-Angel; Lytras, Miltiadis D.

2005-01-01

Purpose: The aim of this paper is introducing the concept of a "semantic learning organization" (SLO) as an extension of the concept of "learning organization" in the technological domain. Design/methodology/approach: The paper takes existing definitions and conceptualizations of both learning organizations and Semantic Web technology to develop…

Differentiation Driven Changes in the Dynamic Organization of Basal Transcription Initiation

PubMed Central

Giglia-Mari, Giuseppina; Mourgues, Sophie; Nonnekens, Julie; Andrieux, Lise O.; de Wit, Jan; Miquel, Catherine; Wijgers, Nils; Maas, Alex; Fousteri, Maria; Hoeijmakers, Jan H. J.; Vermeulen, Wim

2009-01-01

Studies based on cell-free systems and on in vitro–cultured living cells support the concept that many cellular processes, such as transcription initiation, are highly dynamic: individual proteins stochastically bind to their substrates and disassemble after reaction completion. This dynamic nature allows quick adaptation of transcription to changing conditions. However, it is unknown to what extent this dynamic transcription organization holds for postmitotic cells embedded in mammalian tissue. To allow analysis of transcription initiation dynamics directly into living mammalian tissues, we created a knock-in mouse model expressing fluorescently tagged TFIIH. Surprisingly and in contrast to what has been observed in cultured and proliferating cells, postmitotic murine cells embedded in their tissue exhibit a strong and long-lasting transcription-dependent immobilization of TFIIH. This immobilization is both differentiation driven and development dependent. Furthermore, although very statically bound, TFIIH can be remobilized to respond to new transcriptional needs. This divergent spatiotemporal transcriptional organization in different cells of the soma revisits the generally accepted highly dynamic concept of the kinetic framework of transcription and shows how basic processes, such as transcription, can be organized in a fundamentally different fashion in intact organisms as previously deduced from in vitro studies. PMID:19841728

The UF family of hybrid phantoms of the developing human fetus for computational radiation dosimetry

NASA Astrophysics Data System (ADS)

Maynard, Matthew R.; Geyer, John W.; Aris, John P.; Shifrin, Roger Y.; Bolch, Wesley

2011-08-01

Historically, the development of computational phantoms for radiation dosimetry has primarily been directed at capturing and representing adult and pediatric anatomy, with less emphasis devoted to models of the human fetus. As concern grows over possible radiation-induced cancers from medical and non-medical exposures of the pregnant female, the need to better quantify fetal radiation doses, particularly at the organ-level, also increases. Studies such as the European Union's SOLO (Epidemiological Studies of Exposed Southern Urals Populations) hope to improve our understanding of cancer risks following chronic in utero radiation exposure. For projects such as SOLO, currently available fetal anatomic models do not provide sufficient anatomical detail for organ-level dose assessment. To address this need, two fetal hybrid computational phantoms were constructed using high-quality magnetic resonance imaging and computed tomography image sets obtained for two well-preserved fetal specimens aged 11.5 and 21 weeks post-conception. Individual soft tissue organs, bone sites and outer body contours were segmented from these images using 3D-DOCTOR™ and then imported to the 3D modeling software package Rhinoceros™ for further modeling and conversion of soft tissue organs, certain bone sites and outer body contours to deformable non-uniform rational B-spline surfaces. The two specimen-specific phantoms, along with a modified version of the 38 week UF hybrid newborn phantom, comprised a set of base phantoms from which a series of hybrid computational phantoms was derived for fetal ages 8, 10, 15, 20, 25, 30, 35 and 38 weeks post-conception. The methodology used to construct the series of phantoms accounted for the following age-dependent parameters: (1) variations in skeletal size and proportion, (2) bone-dependent variations in relative levels of bone growth, (3) variations in individual organ masses and total fetal masses and (4) statistical percentile variations in skeletal size, individual organ masses and total fetal masses. The resulting series of fetal hybrid computational phantoms is applicable to organ-level and bone-level internal and external radiation dosimetry for human fetuses of various ages and weight percentiles

Implications of Information Theory for Computational Modeling of Schizophrenia.

PubMed

Silverstein, Steven M; Wibral, Michael; Phillips, William A

2017-10-01

Information theory provides a formal framework within which information processing and its disorders can be described. However, information theory has rarely been applied to modeling aspects of the cognitive neuroscience of schizophrenia. The goal of this article is to highlight the benefits of an approach based on information theory, including its recent extensions, for understanding several disrupted neural goal functions as well as related cognitive and symptomatic phenomena in schizophrenia. We begin by demonstrating that foundational concepts from information theory-such as Shannon information, entropy, data compression, block coding, and strategies to increase the signal-to-noise ratio-can be used to provide novel understandings of cognitive impairments in schizophrenia and metrics to evaluate their integrity. We then describe more recent developments in information theory, including the concepts of infomax, coherent infomax, and coding with synergy, to demonstrate how these can be used to develop computational models of schizophrenia-related failures in the tuning of sensory neurons, gain control, perceptual organization, thought organization, selective attention, context processing, predictive coding, and cognitive control. Throughout, we demonstrate how disordered mechanisms may explain both perceptual/cognitive changes and symptom emergence in schizophrenia. Finally, we demonstrate that there is consistency between some information-theoretic concepts and recent discoveries in neurobiology, especially involving the existence of distinct sites for the accumulation of driving input and contextual information prior to their interaction. This convergence can be used to guide future theory, experiment, and treatment development.

Implications of Information Theory for Computational Modeling of Schizophrenia

PubMed Central

Wibral, Michael; Phillips, William A.

2017-01-01

Information theory provides a formal framework within which information processing and its disorders can be described. However, information theory has rarely been applied to modeling aspects of the cognitive neuroscience of schizophrenia. The goal of this article is to highlight the benefits of an approach based on information theory, including its recent extensions, for understanding several disrupted neural goal functions as well as related cognitive and symptomatic phenomena in schizophrenia. We begin by demonstrating that foundational concepts from information theory—such as Shannon information, entropy, data compression, block coding, and strategies to increase the signal-to-noise ratio—can be used to provide novel understandings of cognitive impairments in schizophrenia and metrics to evaluate their integrity. We then describe more recent developments in information theory, including the concepts of infomax, coherent infomax, and coding with synergy, to demonstrate how these can be used to develop computational models of schizophrenia-related failures in the tuning of sensory neurons, gain control, perceptual organization, thought organization, selective attention, context processing, predictive coding, and cognitive control. Throughout, we demonstrate how disordered mechanisms may explain both perceptual/cognitive changes and symptom emergence in schizophrenia. Finally, we demonstrate that there is consistency between some information-theoretic concepts and recent discoveries in neurobiology, especially involving the existence of distinct sites for the accumulation of driving input and contextual information prior to their interaction. This convergence can be used to guide future theory, experiment, and treatment development. PMID:29601053

Peer Attachment, Perceived Parenting Style, Self-concept, and School Adjustments in Adolescents with Chronic Illness.

PubMed

Ahn, Jeong-Ah; Lee, Sunhee

2016-12-01

The purpose of this study was to identify how peer attachment and parenting style differentially affect self-concept and school adjustment in adolescents with and without chronic illness. A cross-sectional study using multiple group analysis on the Korean panel data was used. A nationwide stratified multistage cluster sampling method was used and the survey was conducted in 2013 on 2,092 first-year middle school students in Korea. We used standardized instruments by the National Youth Policy Institute to measure peer attachment, parenting style, self-concept, and school adjustment. Multiple-group structural equation modeling was used to evaluate the difference of relations for peer attachment, parenting style, self-concept, and school adjustment variable between adolescents with chronic illness and those without chronic illness. The model fit of a multiple-group structural equation modeling was good. The difference of the path from negative parenting style to self-concept between the two groups was significant, and a significant between-group difference in the overall path was found. This indicated that self-concept in adolescents with chronic illness was more negatively affected by negative parenting style than in adolescents without chronic illness. Healthcare providers can promote the process of school adjustment in several ways, such as discussing this issue directly with adolescent patients, along with their parents and peers, examining how the organization and content of the treatment can be modified according to the adolescents' school life. Copyright © 2016. Published by Elsevier B.V.

Emotional Intelligence: Theory and Description--A Competency Model for Interpersonal Effectiveness

ERIC Educational Resources Information Center

Kunnanatt, James Thomas

2008-01-01

Purpose: Despite the crucial role that emotional intelligence (EI) could play in improving individuals' performance and career prospects in organizations, employees, executives and career professionals across the world are still in search of practical frameworks for understanding the concept. This is because EI research outputs from academics…

Z39.50 and the Scholar's Workstation Concept.

ERIC Educational Resources Information Center

Phillips, Gary Lee

1992-01-01

Examines the potential application of the American National Standards Institute (ANSI)/National Information Standards Organization (NISO) Z39.50 library networking protocol as a client/server environment for a scholar's workstation. Computer networking models are described, and linking the workstation to an online public access catalog (OPAC) is…

Assessment in the Learning Organization: Shifting the Paradigm.

ERIC Educational Resources Information Center

Costa, Arthur L., Ed.; Kallick, Bena, Ed.

This collection provides a new perspective for understanding what assessment can do to promote continuous improvement in education. The concepts of systems thinking, continued learning, mental models, shared vision, and team building are highlighted in the selections, which include: (1) "A Systems Approach to Assessing School Culture"…

Basic Curriculum Guide--Science. Grades K-6.

ERIC Educational Resources Information Center

Starr, John W., 3rd., Ed.

GRADES OR AGES: K-6. SUBJECT MATTER: Science. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is in two parts--the background, philosophy, and instructional principles of science teaching, including a resource unit model, and the development by grade level of the various basic scientific concepts. The guide also includes information of…

Sustaining Change in a Learning Organization

ERIC Educational Resources Information Center

Steenekamp, K.; Botha, G.; Moloi, K. C.

2012-01-01

This article looks at how the application of the concept of a "learning organisation" can be used at a specific organisation in South Africa to change the work performance of its employees. We do this by exploring different theories, models and definitions of organisational learning, learning organisation, organisational knowledge and…

Employee Upgrading for a Quality Workforce.

ERIC Educational Resources Information Center

Drier, Harry N.; And Others

This training program is a model for recruiting and training counselors to address the career development and educational planning needs of current employees. Section A is directed to the instructor who will train counselors to provide career development assistance to employees of an organization. It describes the program concept and discusses…

Counseling in the Enterprise Culture.

ERIC Educational Resources Information Center

Cummins, Anne-Marie; Hoggett, Paul

1995-01-01

Describes the way therapeutic models and language have been used in support of human flexibility and "human resource development" concepts in the 1980s and 1990s. Examines use of humane managerial rhetoric to mask practice of increasingly ruthless public and private-sector organizations, and the dilemmas for counselors operating within these kinds…

Exploring the Role of Goal Theory in Understanding Training Motivation

ERIC Educational Resources Information Center

Smith, Rebecca; Jayasuriya, Rohan; Caputi, Peter; Hammer, David

2008-01-01

A model to test conceptions from goal theory within an existing framework of training motivation was developed and tested with employees participating in training in a non-profit organization. It was hypothesized that goal orientation ("distal factors") along with self-efficacy, expectancy and valence ("proximal factors") would predict goal…

A Conceptual Model of Observed Physical Literacy

ERIC Educational Resources Information Center

Dudley, Dean A.

2015-01-01

Physical literacy is a concept that is gaining greater acceptance around the world with the United Nations Educational, Cultural, and Scientific Organization (2013) recognizing it as one of several central tenets in a quality physical education framework. However, previous attempts to understand progression in physical literacy learning have been…

Expanding the conceptual toolkit of organ gifting.

PubMed

M Shaw, Rhonda

2015-07-01

In jurisdictions where the sale of body tissue and organs is illegal, organ transplantation is often spoken of as a gift of life. In the social sciences and bioethics this concept has been subject to critique over the course of the last two decades for failing to reflect the complexities of organ and tissue exchange. I suggest that a new ethical model of organ donation and transplantation is needed to capture the range of experiences in this domain. The proposed model is both analytical and empirically oriented, and draws on research findings linking a series of qualitative sociological studies undertaken in New Zealand between 2007 and 2013. The studies were based on document analysis, field notes and 127 semi-structured in-depth interviews with people from different cultural and constituent groups directly involved in organ transfer processes. The aim of the article is to contribute to sociological knowledge about organ exchange and to expand the conceptual toolkit of organ donation to include the unconditional gift, the gift relation, gift exchange, body project, and body work. The rationale for the proposed model is to provide an explanatory framework for organ donors and transplant recipients and to assist the development of ethical guidelines and health policy discourse. © 2015 Foundation for the Sociology of Health & Illness.

Culture and Demography: From Reluctant Bedfellows to Committed Partners

PubMed Central

Bachrach, Christine A.

2015-01-01

Demography and culture have had a long but ambivalent relationship. Cultural influences are widely recognized as important for demographic outcomes, but are often “backgrounded” in demographic research. I argue that progress towards a more successful integration is feasible and suggest a network model of culture as a potential tool. The network model bridges both traditional (holistic and institutional) and contemporary (tool kit) models of culture used in the social sciences and offers a simple vocabulary for the diverse set of cultural concepts such as attitudes, beliefs and norms, and quantitative measures of how culture is organized. The proposed model conceptualizes culture as a nested network of meanings which are represented by schemas that range in complexity from simple concepts to multifaceted cultural models. I illustrate the potential value of a model using accounts of the cultural changes underpinning the transformation of marriage in the U.S. and point to developments in the social, cognitive and computational sciences that could facilitate the application of the model in empirical demographic research. PMID:24338643

Culture and demography: from reluctant bedfellows to committed partners.

PubMed

Bachrach, Christine A

2014-02-01

Demography and culture have had a long but ambivalent relationship. Cultural influences are widely recognized as important for demographic outcomes but are often "backgrounded" in demographic research. I argue that progress toward a more successful integration is feasible and suggest a network model of culture as a potential tool. The network model bridges both traditional (holistic and institutional) and contemporary (tool kit) models of culture used in the social sciences and offers a simple vocabulary for a diverse set of cultural concepts, such as attitudes, beliefs, and norms, as well as quantitative measures of how culture is organized. The proposed model conceptualizes culture as a nested network of meanings represented by schemas that range in complexity from simple concepts to multifaceted cultural models. I illustrate the potential value of a model using accounts of the cultural changes underpinning the transformation of marriage in the United States and point to developments in the social, cognitive, and computational sciences that could facilitate the application of the model in empirical demographic research.

Planning an organizational wellness initiative at a multi-state social service agency.

PubMed

Miller, J Jay; Grise-Owens, Erlene; Addison, Donia; Marshall, Midaya; Trabue, Donna; Escobar-Ratliff, Laura

2016-06-01

Increasingly, organizations in general, and social service organizations, specifically, are recognizing the importance of planning and evaluating organizational wellness initiatives. Yet, few participatory models for carrying out these aims exist. For this study, researchers utilized concept mapping (CM) to explicate a conceptual framework for planning, and subsequently evaluating, a wellness initiative at a multi-state social service organization. CM is a participatory approach that analyzes qualitative data via multi-dimensional scaling and hierarchical cluster analyses. Outputs include a number of visual depictions that allow researchers to explore complex relationships among sets of the data. Results from this study indicated that participants (N=64), all of whom were employees of the agency, conceptualized organizational wellness via an eight-cluster solution, or Concept Map. Priority areas of this framework, specifically importance and feasibility, were also explored. After a brief review of pertinent literature, this article explicates the CM methodology utilized in this study, describes results, discusses lessons learned, and identifies apt areas for future research. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mechanisms of Soil Aggregation: a biophysical modeling framework

NASA Astrophysics Data System (ADS)

Ghezzehei, T. A.; Or, D.

2016-12-01

Soil aggregation is one of the main crosscutting concepts in all sub-disciplines and applications of soil science from agriculture to climate regulation. The concept generally refers to adhesion of primary soil particles into distinct units that remain stable when subjected to disruptive forces. It is one of the most sensitive soil qualities that readily respond to disturbances such as cultivation, fire, drought, flooding, and changes in vegetation. These changes are commonly quantified and incorporated in soil models indirectly as alterations in carbon content and type, bulk density, aeration, permeability, as well as water retention characteristics. Soil aggregation that is primarily controlled by organic matter generally exhibits hierarchical organization of soil constituents into stable units that range in size from a few microns to centimeters. However, this conceptual model of soil aggregation as the key unifying mechanism remains poorly quantified and is rarely included in predictive soil models. Here we provide a biophysical framework for quantitative and predictive modeling of soil aggregation and its attendant soil characteristics. The framework treats aggregates as hotspots of biological, chemical and physical processes centered around roots and root residue. We keep track of the life cycle of an individual aggregate from it genesis in the rhizosphere, fueled by rhizodeposition and mediated by vigorous microbial activity, until its disappearance when the root-derived resources are depleted. The framework synthesizes current understanding of microbial life in porous media; water holding and soil binding capacity of biopolymers; and environmental controls on soil organic matter dynamics. The framework paves a way for integration of processes that are presently modeled as disparate or poorly coupled processes, including storage and protection of carbon, microbial activity, greenhouse gas fluxes, movement and storage of water, resistance of soils against erosion.

The synthesis map is a multidimensional educational tool that provides insight into students' mental models and promotes students' synthetic knowledge generation.

PubMed

Ortega, Ryan A; Brame, Cynthia J

2015-01-01

Concept mapping was developed as a method of displaying and organizing hierarchical knowledge structures. Using the new, multidimensional presentation software Prezi, we have developed a new teaching technique designed to engage higher-level skills in the cognitive domain. This tool, synthesis mapping, is a natural evolution of concept mapping, which utilizes embedding to layer information within concepts. Prezi's zooming user interface lets the author of the presentation use both depth as well as distance to show connections between data, ideas, and concepts. Students in the class Biology of Cancer created synthesis maps to illustrate their knowledge of tumorigenesis. Students used multiple organizational schemes to build their maps. We present an analysis of student work, placing special emphasis on organization within student maps and how the organization of knowledge structures in student maps can reveal strengths and weaknesses in student understanding or instruction. We also provide a discussion of best practices for instructors who would like to implement synthesis mapping in their classrooms. © 2015 R. A. Ortega and C. J. Brame et al. CBE—Life Sciences Education © 2015 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

A post-Bertalanffy Systemics Healthcare Competitive Framework Proposal.

PubMed

Fiorini, Rodolfo A; Santacroce, Giulia F

2014-01-01

Health Information community can take advantage of a new evolutive categorization cybernetic framework. A systemic concept of principles organizing nature is proposed. It can be used as a multiscaling reference framework to develop successful and competitive antifragile system and new HRO information management strategies in advanced healthcare organization (HO) and high reliability organization (HRO) conveniently. Expected impacts are multifarious and quite articulated at different system scale level: major one is that, for the first time, Biomedical Engineering ideal system categorization levels can be matched exactly to practical system modeling interaction styles, with no paradigmatic operational ambiguity and information loss.

Women and Consciousness in the "Learning Organization": Emancipation or Exploitation?

ERIC Educational Resources Information Center

Mojab, Shahrzad; Gorman, Rachel

2003-01-01

Marxist-feminist analysis of the learning organization concept demonstrates that , instead of being emancipatory, it can function as a way to extract surplus value from labor and to maintain social control. Pressures on feminist-oriented nonprofit organizations to adopt the learning organization concept could erode consciousness raising and…

Six Pillars of Organic Chemistry

ERIC Educational Resources Information Center

Mullins, Joseph J.

2008-01-01

This article describes an approach to teaching organic chemistry, which is to have students build their knowledge of organic chemistry upon a strong foundation of the fundamental concepts of the subject. Specifically, the article focuses upon a core set of concepts that I call "the six pillars of organic chemistry": electronegativity, polar…

Knowledge Co-production Strategies for Water Resources Modeling and Decision Making

NASA Astrophysics Data System (ADS)

Gober, P.

2016-12-01

The limited impact of scientific information on policy making and climate adaptation in North America has raised awareness of the need for new modeling strategies and knowledge transfer processes. This paper outlines the rationale for a new paradigm in water resources modeling and management, using examples from the USA and Canada. Principles include anticipatory modeling, complex system dynamics, decision making under uncertainty, visualization, capacity to represent and manipulate critical trade-offs, stakeholder engagement, local knowledge, context-specific activities, social learning, vulnerability analysis, iterative and collaborative modeling, and the concept of a boundary organization. In this framework, scientists and stakeholders are partners in the production and dissemination of knowledge for decision making, and local knowledge is fused with scientific observation and methodology. Discussion draws from experience in building long-term collaborative boundary organizations in Phoenix, Arizona in the USA and the Saskatchewan River Basin (SRB) in Canada. Examples of boundary spanning activities include the use of visualization, the concept of a decision theater, infrastructure to support social learning, social networks, and reciprocity, simulation modeling to explore "what if" scenarios of the future, surveys to elicit how water problems are framed by scientists and stakeholders, and humanistic activities (theatrical performances, art exhibitions, etc.) to draw attention to local water issues. The social processes surrounding model development and dissemination are at least as important as modeling assumptions, procedures, and results in determining whether scientific knowledge will be used effectively for water resources decision making.

Validation of Bioreactor and Human-on-a-Chip Devices for Chemical Safety Assessment.

PubMed

Rebelo, Sofia P; Dehne, Eva-Maria; Brito, Catarina; Horland, Reyk; Alves, Paula M; Marx, Uwe

2016-01-01

Equipment and device qualification and test assay validation in the field of tissue engineered human organs for substance assessment remain formidable tasks with only a few successful examples so far. The hurdles seem to increase with the growing complexity of the biological systems, emulated by the respective models. Controlled single tissue or organ culture in bioreactors improves the organ-specific functions and maintains their phenotypic stability for longer periods of time. The reproducibility attained with bioreactor operations is, per se, an advantage for the validation of safety assessment. Regulatory agencies have gradually altered the validation concept from exhaustive "product" to rigorous and detailed process characterization, valuing reproducibility as a standard for validation. "Human-on-a-chip" technologies applying micro-physiological systems to the in vitro combination of miniaturized human organ equivalents into functional human micro-organisms are nowadays thought to be the most elaborate solution created to date. They target the replacement of the current most complex models-laboratory animals. Therefore, we provide here a road map towards the validation of such "human-on-a-chip" models and qualification of their respective bioreactor and microchip equipment along a path currently used for the respective animal models.

Development and Assessment of a Diagnostic Tool to Identify Organic Chemistry Students' Alternative Conceptions Related to Acid Strength

ERIC Educational Resources Information Center

McClary, LaKeisha M.; Bretz, Stacey Lowery

2012-01-01

The central goal of this study was to create a new diagnostic tool to identify organic chemistry students' alternative conceptions related to acid strength. Twenty years of research on secondary and college students' conceptions about acids and bases has shown that these important concepts are difficult for students to apply to qualitative problem…

Organizing knowledge for tutoring fire loss prevention

NASA Astrophysics Data System (ADS)

Schmoldt, Daniel L.

1989-09-01

The San Bernardino National Forest in southern California has recently developed a systematic approach to wildfire prevention planning. However, a comprehensive document or other mechanism for teaching this process to other prevention personnel does not exist. An intelligent tutorial expert system is being constructed to provide a means for learning the process and to assist in the creation of specific prevention plans. An intelligent tutoring system (ITS) contains two types of knowledge—domain and tutoring. The domain knowledge for wildfire prevention is structured around several foci: (1) individual concepts used in prevention planning; (2) explicitly specified interrelationships between concepts; (3) deductive methods that contain subjective judgment normally unavailable to less-experienced users; (4) analytical models of fire behavior used for identification of hazard areas; (5) how-to guidance needed for performance of planning tasks; and (6) expository information that provides a rationale for planning steps and ideas. Combining analytical, procedure, inferential, conceptual, and expositional knowledge into a tutoring environment provides the student and/or user with a multiple perspective of the subject matter. A concept network provides a unifying framework for structuring and utilizing these diverse forms of prevention planning knowledge. This network structure borrows from and combines semantic networks and frame-based knowledge representations. The flexibility of this organization facilitates an effective synthesis and organization of multiple knowledge forms.

Neurodynamic system theory: scope and limits.

PubMed

Erdi, P

1993-06-01

This paper proposes that neurodynamic system theory may be used to connect structural and functional aspects of neural organization. The paper claims that generalized causal dynamic models are proper tools for describing the self-organizing mechanism of the nervous system. In particular, it is pointed out that ontogeny, development, normal performance, learning, and plasticity, can be treated by coherent concepts and formalism. Taking into account the self-referential character of the brain, autopoiesis, endophysics and hermeneutics are offered as elements of a poststructuralist brain (-mind-computer) theory.

A novel paradigm for cell and molecule interaction ontology: from the CMM model to IMGT-ONTOLOGY

PubMed Central

2010-01-01

Background Biology is moving fast toward the virtuous circle of other disciplines: from data to quantitative modeling and back to data. Models are usually developed by mathematicians, physicists, and computer scientists to translate qualitative or semi-quantitative biological knowledge into a quantitative approach. To eliminate semantic confusion between biology and other disciplines, it is necessary to have a list of the most important and frequently used concepts coherently defined. Results We propose a novel paradigm for generating new concepts for an ontology, starting from model rather than developing a database. We apply that approach to generate concepts for cell and molecule interaction starting from an agent based model. This effort provides a solid infrastructure that is useful to overcome the semantic ambiguities that arise between biologists and mathematicians, physicists, and computer scientists, when they interact in a multidisciplinary field. Conclusions This effort represents the first attempt at linking molecule ontology with cell ontology, in IMGT-ONTOLOGY, the well established ontology in immunogenetics and immunoinformatics, and a paradigm for life science biology. With the increasing use of models in biology and medicine, the need to link different levels, from molecules to cells to tissues and organs, is increasingly important. PMID:20167082

The Application of Learning Organization to Enhance Learning in Singapore Schools

ERIC Educational Resources Information Center

Retna, Kala S.; Ng, Pak Tee

2016-01-01

The rise of interest in the learning organization (LO) concept attests to the value of learning by individuals and organizations for continuous improvement and adaptability to the ever-changing environment. Although the LO concept originated from business contexts, it was subsequently extended to educational organizations, particularly to schools.…

Evaluating the multimedia fate of organic chemicals: A level III fugacity model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mackay, D.; Paterson, S.

A multimedia model is developed and applied to selected organic chemicals in evaluative and real regional environments. The model employs the fugacity concept and treats four bulk compartments: air, water, soil, and bottom sediment, which consist of subcompartments of varying proportions of air, water, and mineral and organic matter. Chemical equilibrium is assumed to apply within (but not between) each bulk compartment. Expressions are included for emissions, advective flows, degrading reactions, and interphase transport by diffusive and non-diffusive processes. Input to the model consists of a description of the environment, the physical-chemical and reaction properties of the chemical, and emissionmore » rates. For steady-state conditions the solution is a simple algebraic expression. The model is applied to six chemicals in the region of southern Ontario and the calculated fate and concentrations are compared with observations. The results suggest that the model may be used to determine the processes that control the environmental fate of chemicals in a region and provide approximate estimates of relative media concentrations.« less

Ontology patterns for complex topographic feature yypes

USGS Publications Warehouse

Varanka, Dalia E.

2011-01-01

Complex feature types are defined as integrated relations between basic features for a shared meaning or concept. The shared semantic concept is difficult to define in commonly used geographic information systems (GIS) and remote sensing technologies. The role of spatial relations between complex feature parts was recognized in early GIS literature, but had limited representation in the feature or coverage data models of GIS. Spatial relations are more explicitly specified in semantic technology. In this paper, semantics for topographic feature ontology design patterns (ODP) are developed as data models for the representation of complex features. In the context of topographic processes, component assemblages are supported by resource systems and are found on local landscapes. The topographic ontology is organized across six thematic modules that can account for basic feature types, resource systems, and landscape types. Types of complex feature attributes include location, generative processes and physical description. Node/edge networks model standard spatial relations and relations specific to topographic science to represent complex features. To demonstrate these concepts, data from The National Map of the U. S. Geological Survey was converted and assembled into ODP.

Virtual Organizations: An Overview

NASA Astrophysics Data System (ADS)

Nami, Mohammad Reza

The need to remain competitive in the open market forces companies to concentrate on their core competencies while searching for alliances when additional skills or resources are needed to fulfill business opportunities. The changing business situation of companies and customer needs have motivated researchers to introduce Virtual Organization (VO) idea. A Virtual Organization is always a form of partnership and managing partners and handling partnerships are crucial. Virtual organizations are defined as a temporary collection of enterprises that cooperate and share resources, knowledge, and competencies to better respond to business opportunities. This paper presents base concepts of virtual organizations including properties, management concepts, operational concepts, and main issues in collaboration such as security and authentication.

["Group" and organization: a dimension of collaboration of anthropology and epidemiology].

PubMed

Song, Lei-ming; Wang, Ning

2012-04-01

"Group" is a key concept in epidemiological research and "organization" is a core concept in anthropology. Group takes focus on the specific characteristics of the subjects, while organization takes focus on the relationship between the objects. For the characteristics and relationship of the objects that interacting with each other, the two concepts could be complementary in specific studies, and this will be the basic dimension of Interdisciplinary collaboration of anthropology and epidemiology.

Do written mandatory accreditation standards for residential care positively model learning organizations? Textual and critical discourse analysis.

PubMed

Bell, Erica; Robinson, Andrew; See, Catherine

2013-11-01

Unprecedented global population ageing accompanied by increasing complexity of aged care present major challenges of quality in aged care. In the business literature, Senge's theory of adaptive learning organisations offers a model of organisational quality. However, while accreditation of national standards is an increasing mechanism for achieving quality in aged care, there are anecdotal concerns it creates a 'minimum standards compliance mentality' and no evidence about whether it reinforces learning organisations. The research question was 'Do mandatory national accreditation standards for residential aged care, as they are written, positively model learning organisations?'. Automatic text analysis was combined with critical discourse analysis to analyse the presence of learning concepts from Senge's learning organisation theory in an exhaustive sample of national accreditation standards from 7 countries. The two stages of analysis were: (1) quantitative mapping of the presence of learning organisation concepts in standards using Bayesian-based textual analytics software and (2) qualitative critical discourse analysis to further examine how the language of standards so identified may be modelling learning organisation concepts. The learning concepts 'training', 'development', 'knowledge', and 'systems' are present with relative frequencies of 19%, 11%, 10%, and 10% respectively in the 1944 instances, in paragraph-sized text blocks, considered. Concepts such as 'team', 'integration', 'learning', 'change' and 'innovation' occur with 7%, 6%, 5%, 5%, and 1% relative frequencies respectively. Learning concepts tend to co-occur with negative rather than positive sentiment language in the 3176 instances in text blocks containing sentiment language. Critical discourse analysis suggested that standards generally use the language of organisational change and learning in limited ways that appear to model 'learning averse' communities of practice and organisational cultures. The aged care quality challenge and the role of standards need rethinking. All standards implicitly or explicitly model an organisation of some type. If standards can model a limited and negative learning organisation language, they could model a well-developed and positive learning organisation language. In the context of the global aged care crisis, the modelling of learning organisations is probably critical for minimal competence in residential aged care and certainly achievable in the language of standards. Copyright © 2013 Elsevier Ltd. All rights reserved.

EPOS: Integrating seismological Research Infrastructures within Europe

NASA Astrophysics Data System (ADS)

Eck Van, Torild; Clinton, John; Haslinger, Florian; Michelini, Alberto

2013-04-01

Seismological data, products and models are currently produced in Europe within individual countries or research organizations, and with the contribution of coordinating organizations like ORFEUS and EMSC. In spite of these partly scattered resources, significant scientific results are obtained, excellent monitoring and information systems are operational and a huge amount of research quality data is being archived and disseminated. The seismological community, however, realizes that an effective European-scale integration of seismological and related geophysical data, products and models, combined with broad and easy access, is needed to facilitate future top level geoscience, for example, to appropriately harness the technological advancements enabling large scale and near-real time data processing. Here we present the technical concepts and developments within European seismology that will build the next generation of integrated services. Within the EPOS initiative and a number of related projects, where seismology infrastructure and IT developments are merging, in depth discussions are on-going on how to realize an effective integration. Concepts and visions addressing the obviously complex challenges resulting from the current highly distributed facilities and resources in Europe are emerging and are already partly being implemented. We will provide an overview of developments within key EU projects (NERA, VERCE, COOPEUS, EUDAT, REAKT, COMMIT, etc) and demonstrate how these are in coherence with EPOS and other on-going global initiatives. Within seismology current focus is on addressing IT related challenges to a) organize distributed data archives, develop metadata attributes for improved data searching, specifically including quality indicators, and define products from data and/or models, and b) define and create(on-line) monitoring, data access and processing tools. While developments to meet those challenges originate partly from within the community itself, it is important to harvest relevant ideas and tools from other scientific communities dealing with similar issues. We will present a short summary of those developments and how they fit within the proposed visions and concepts. These integration developments address a wide framework of seismological services that include: basic seismological data services (waveform data from velocity and acceleration sensors from land and underwater sites); seismological data products (source mechanism and process estimates, earthquake catalogues, structural and tomography model estimations); seismological models (synthetic waveforms, earth and earthquake source models, hazard models).Our aim is to build significantlyimproved seismological services and valuable products for multidisciplinary earth science research.

Towards a Competency Model: A Review of the Literature and the Competency Standards

ERIC Educational Resources Information Center

El Asame, Maryam; Wakrim, Mohamed

2018-01-01

Competency-based approaches using information and communication technologies have been the main solution of the organization's expectations in all fields (public and private) to increase the products' quality and employees' capacity. Furthermore, the concept of competency can have several different definitions, which may make it difficult to…

Psychological Entropy: A Framework for Understanding Uncertainty-Related Anxiety

ERIC Educational Resources Information Center

Hirsh, Jacob B.; Mar, Raymond A.; Peterson, Jordan B.

2012-01-01

Entropy, a concept derived from thermodynamics and information theory, describes the amount of uncertainty and disorder within a system. Self-organizing systems engage in a continual dialogue with the environment and must adapt themselves to changing circumstances to keep internal entropy at a manageable level. We propose the entropy model of…

A Proposed Blueprint Model towards the Evaluation of Educational System in Iran

ERIC Educational Resources Information Center

Mehrafsha, S. Jahangir

2011-01-01

The pursuit of quality gave rise to the concept of Iran Universities as learning organizations. Iran Universities must have the capacity to learn if they are to survive the demands and requirements of the emerging times. This includes liberating traditional methodologies that are anchored on positivism and seemingly dependent on technical…

Combining a Standard Fischer Esterification Experiment with Stereochemical and Molecular-Modeling Concepts

ERIC Educational Resources Information Center

Clausen, Thomas P.

2011-01-01

The Fisher esterification reaction is ideally suited for the undergraduate organic laboratory because it is easy to carry out and often involves a suitable introduction to basic laboratory techniques including extraction, distillation, and simple spectroscopic (IR and NMR) analyses. Here, a Fisher esterification reaction is described in which the…

Planned Change in Future Models of Project Follow Through: A Concept Paper.

ERIC Educational Resources Information Center

Simpkins, Edward; Brown, Asa

The three chapters included in this paper establish a basis for organizing future implementations of Project Follow Through. Specifically, chapter 1 identifies four planning objectives for coordinating such programs. Emphasis is given to the need to focus on one fundamental, pervasive variable possibly accounting for program success: time…

The Student Support Team as a Professional Learning Community.

ERIC Educational Resources Information Center

DuFour, Richard; Guidice, Aida; Magee, Deborah; Martin, Patricia; Zivkovic, Barbara

This chapter discusses three emerging national trends that could serve as catalysts for fundamental change in student services programs. First is the concept of the learning organization, which offers a superior model for enhancing the effectiveness of institutions and the people within them. Second is the movement away from standardization and…

Self, System, Synergy: A Career-Life Development Framework for Individuals and Organizations.

ERIC Educational Resources Information Center

Gelatt, H. B.

1998-01-01

The Self-System-Synergy model provides the philosophical framework for the concept of career resiliency, which has become the basis for many organizational initiatives. The three elements are self-reliance (the power of personal beliefs), interdependence (the connectedness of multiple systems), and self-renewal through continuous learning. (JOW)

From Quick Start Teams to Home Teams: The Duke TQM Experience.

ERIC Educational Resources Information Center

Lubans, John; Gordon, Heather

This paper describes the Duke University Libraries' transition in early 1994 from its traditional hierarchical model to an organization emphasizing Total Quality Management (TQM) concepts such as self-managing teams and continuous improvement. Existing conditions at the libraries that played a role in the decision to switch included: (1) rising…

Planned Organizational Change; A Study in Change Dynamics.

ERIC Educational Resources Information Center

Jones, Garth N.

This study attempts to develop a broad model or concept, based largely on empirical evidence, which applies social science knowledge and methodology to the planning of change in corporations, armies, schools, hospitals, government, community groups, and other formal and informal organizations. Chapters 2,3, and 4 define and discuss the roles of…

76 FR 43738 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

... filed an immediately effective proposal regarding Remote Specialists (the ``Remote Specialist filing'') that expanded the Remote Specialist concept.\\3\\ By the Remote Specialist filing, the Exchange enhanced the existing Remote Specialist \\4\\ model so that all eligible ROTs \\5\\ on the Exchange could function...

Learning to Manage Intergroup Dynamics in Changing Task Environments: An Experiential Exercise

ERIC Educational Resources Information Center

Hunsaker, Phillip L.

2004-01-01

This article describes an exercise that allows participants to experience the challenges of managing intergroup behavior as an organization's task environment grows and becomes more complex. The article begins with a brief review of models and concepts relating to intergroup dynamics, intergroup conflict, and interventions for effectively managing…

Bibliographic Networks and Microcomputer Applications for Aerospace and Defense Scientific and Technical Information.

ERIC Educational Resources Information Center

Hartt, Richard W.

This report discusses the characteristics, operations, and automation requirements of technical libraries providing services to organizations involved in aerospace and defense scientific and technical work, and describes the Local Automation Model project. This on-going project is designed to demonstrate the concept of a fully integrated library…

Global Information Justice: Rights, Responsibilities, and Caring Connections.

ERIC Educational Resources Information Center

Smith, Martha

2001-01-01

Explains the concept of global information justice and describes it as an ethical ideal, as an organizing principle for a model for analysis, and as a direction for policy making. Discusses the use of new technologies; access to technology; ownership; privacy; security; community; and the Universal Declaration of Human Rights. (Author/LRW)

Some New Theoretical Issues in Systems Thinking Relevant for Modelling Corporate Learning

ERIC Educational Resources Information Center

Minati, Gianfranco

2007-01-01

Purpose: The purpose of this paper is to describe fundamental concepts and theoretical challenges with regard to systems, and to build on these in proposing new theoretical frameworks relevant to learning, for example in so-called learning organizations. Design/methodology/approach: The paper focuses on some crucial fundamental aspects introduced…

Servant Leader Development at Southeastern University

ERIC Educational Resources Information Center

Rohm, Fredric W., Jr.

2013-01-01

Servant leadership as envisioned by Robert Greenleaf (1970) is a philosophy whereby leaders put the interests and growth of the follower ahead of themselves. Though the concept has been around since antiquity, scholars and practitioners in organizations began to embrace and expand the idea since the early 1990s. There are currently 20 models of…

Doctrine Development Process in the Kenya Army: Bridging the Gap

DTIC Science & Technology

2014-06-13

concepts, and principles . It must broadly follow three doctrine development phases: the collection/information gathering phase; the formulation and...a capable lead organization. The organization must eliminate terminological and utility confusion among doctrine, concepts, and principles . It must...15 The relationship Between Military Doctrine, Concept and Principle

40 CFR 300.105 - General organization concepts.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PLAN Responsibility and Organization for Response § 300.105 General organization concepts. (a) Federal agencies should: (1) Plan for emergencies and develop procedures for addressing oil discharges and releases... activated during a response. RRT membership consists of designated representatives from each federal agency...

40 CFR 300.105 - General organization concepts.

Code of Federal Regulations, 2012 CFR

2012-07-01

... PLAN Responsibility and Organization for Response § 300.105 General organization concepts. (a) Federal agencies should: (1) Plan for emergencies and develop procedures for addressing oil discharges and releases... activated during a response. RRT membership consists of designated representatives from each federal agency...

A Linguistic Model in Component Oriented Programming

NASA Astrophysics Data System (ADS)

Crăciunean, Daniel Cristian; Crăciunean, Vasile

2016-12-01

It is a fact that the component-oriented programming, well organized, can bring a large increase in efficiency in the development of large software systems. This paper proposes a model for building software systems by assembling components that can operate independently of each other. The model is based on a computing environment that runs parallel and distributed applications. This paper introduces concepts as: abstract aggregation scheme and aggregation application. Basically, an aggregation application is an application that is obtained by combining corresponding components. In our model an aggregation application is a word in a language.

Foundations of “new” social science: Institutional legitimacy from philosophy, complexity science, postmodernism, and agent-based modeling

PubMed Central

Henrickson, Leslie; McKelvey, Bill

2002-01-01

Since the death of positivism in the 1970s, philosophers have turned their attention to scientific realism, evolutionary epistemology, and the Semantic Conception of Theories. Building on these trends, Campbellian Realism allows social scientists to accept real-world phenomena as criterion variables against which theories may be tested without denying the reality of individual interpretation and social construction. The Semantic Conception reduces the importance of axioms, but reaffirms the role of models and experiments. Philosophers now see models as “autonomous agents” that exert independent influence on the development of a science, in addition to theory and data. The inappropriate molding effects of math models on social behavior modeling are noted. Complexity science offers a “new” normal science epistemology focusing on order creation by self-organizing heterogeneous agents and agent-based models. The more responsible core of postmodernism builds on the idea that agents operate in a constantly changing web of interconnections among other agents. The connectionist agent-based models of complexity science draw on the same conception of social ontology as do postmodernists. These recent developments combine to provide foundations for a “new” social science centered on formal modeling not requiring the mathematical assumptions of agent homogeneity and equilibrium conditions. They give this “new” social science legitimacy in scientific circles that current social science approaches lack. PMID:12011408

Organ Transplantation in the Face of Donor Shortage - Ethical Implications with a Focus on Liver Allocation

PubMed Central

Lauerer, Michael; Kaiser, Katharina; Nagel, Eckhard

2016-01-01

Background Transplantation medicine is associated with several ethical issues related to the lack of organs. Major questions concern the regulations for giving permission for organ removal, informing the public about organ donation, setting of organ allocation priorities, waiting list access, and strategies to counteract scarcity. Methods This contribution is based on analyses of legal regulations, guidelines of self-regulatory bodies, administrative data, and literature from medical, normative, and empiric disciplines. It addresses the above-mentioned issues descriptively with a focus on Germany and liver transplantation. Results The basic principle of beneficence justifies a shift from voluntariness towards an obligation to document one's decision regarding organ donation. Organ allocation is obviously tangent to fundamental values and concepts of justice. At that, there is no consistent agreement on whether to prioritize the sickest patient or to maximize the overall health benefit. Restrictions relating to waiting list access are the subject of controversies. The reasons for denial of access are largely related to high demands on the prospect of success. Strategies to counteract organ scarcity partly conflict with the respect for autonomy, non-maleficence, beneficence, or justice. Conclusion We propose to focus on recent most promising strategies to counteract scarcity in the short-term: demanding a documented decision on organ donation and an orientation towards the Spanish model of organization. Concepts for waiting list access should constantly be reviewed considering all medical evidence and must not be based on moralism. Moreover, we suggest to consider public preferences for organ allocation and strengthen the confidence in transplantation medicine. PMID:27722165

Organ Transplantation in the Face of Donor Shortage - Ethical Implications with a Focus on Liver Allocation.

PubMed

Lauerer, Michael; Kaiser, Katharina; Nagel, Eckhard

2016-08-01

Transplantation medicine is associated with several ethical issues related to the lack of organs. Major questions concern the regulations for giving permission for organ removal, informing the public about organ donation, setting of organ allocation priorities, waiting list access, and strategies to counteract scarcity. This contribution is based on analyses of legal regulations, guidelines of self-regulatory bodies, administrative data, and literature from medical, normative, and empiric disciplines. It addresses the above-mentioned issues descriptively with a focus on Germany and liver transplantation. The basic principle of beneficence justifies a shift from voluntariness towards an obligation to document one's decision regarding organ donation. Organ allocation is obviously tangent to fundamental values and concepts of justice. At that, there is no consistent agreement on whether to prioritize the sickest patient or to maximize the overall health benefit. Restrictions relating to waiting list access are the subject of controversies. The reasons for denial of access are largely related to high demands on the prospect of success. Strategies to counteract organ scarcity partly conflict with the respect for autonomy, non-maleficence, beneficence, or justice. We propose to focus on recent most promising strategies to counteract scarcity in the short-term: demanding a documented decision on organ donation and an orientation towards the Spanish model of organization. Concepts for waiting list access should constantly be reviewed considering all medical evidence and must not be based on moralism. Moreover, we suggest to consider public preferences for organ allocation and strengthen the confidence in transplantation medicine.

Advanced soft computing diagnosis method for tumour grading.

PubMed

Papageorgiou, E I; Spyridonos, P P; Stylios, C D; Ravazoula, P; Groumpos, P P; Nikiforidis, G N

2006-01-01

To develop an advanced diagnostic method for urinary bladder tumour grading. A novel soft computing modelling methodology based on the augmentation of fuzzy cognitive maps (FCMs) with the unsupervised active Hebbian learning (AHL) algorithm is applied. One hundred and twenty-eight cases of urinary bladder cancer were retrieved from the archives of the Department of Histopathology, University Hospital of Patras, Greece. All tumours had been characterized according to the classical World Health Organization (WHO) grading system. To design the FCM model for tumour grading, three experts histopathologists defined the main histopathological features (concepts) and their impact on grade characterization. The resulted FCM model consisted of nine concepts. Eight concepts represented the main histopathological features for tumour grading. The ninth concept represented the tumour grade. To increase the classification ability of the FCM model, the AHL algorithm was applied to adjust the weights of the FCM. The proposed FCM grading model achieved a classification accuracy of 72.5%, 74.42% and 95.55% for tumours of grades I, II and III, respectively. An advanced computerized method to support tumour grade diagnosis decision was proposed and developed. The novelty of the method is based on employing the soft computing method of FCMs to represent specialized knowledge on histopathology and on augmenting FCMs ability using an unsupervised learning algorithm, the AHL. The proposed method performs with reasonably high accuracy compared to other existing methods and at the same time meets the physicians' requirements for transparency and explicability.

Modularity in developmental biology and artificial organs: a missing concept in tissue engineering.

PubMed

Lenas, Petros; Luyten, Frank P; Doblare, Manuel; Nicodemou-Lena, Eleni; Lanzara, Andreina Elena

2011-06-01

Tissue engineering is reviving itself, adopting the concept of biomimetics of in vivo tissue development. A basic concept of developmental biology is the modularity of the tissue architecture according to which intermediates in tissue development constitute semiautonomous entities. Both engineering and nature have chosen the modular architecture to optimize the product or organism development and evolution. Bioartificial tissues do not have a modular architecture. On the contrary, artificial organs of modular architecture have been already developed in the field of artificial organs. Therefore the conceptual support of tissue engineering by the field of artificial organs becomes critical in its new endeavor of recapitulating in vitro the in vivo tissue development. © 2011, Copyright the Authors. Artificial Organs © 2011, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

Biologically inspired information theory: Adaptation through construction of external reality models by living systems.

PubMed

Nakajima, Toshiyuki

2015-12-01

Higher animals act in the world using their external reality models to cope with the uncertain environment. Organisms that have not developed such information-processing organs may also have external reality models built in the form of their biochemical, physiological, and behavioral structures, acquired by natural selection through successful models constructed internally. Organisms subject to illusions would fail to survive in the material universe. How can organisms, or living systems in general, determine the external reality from within? This paper starts with a phenomenological model, in which the self constitutes a reality model developed through the mental processing of phenomena. Then, the it-from-bit concept is formalized using a simple mathematical model. For this formalization, my previous work on an algorithmic process is employed to constitute symbols referring to the external reality, called the inverse causality, with additional improvements to the previous work. Finally, as an extension of this model, the cognizers system model is employed to describe the self as one of many material entities in a world, each of which acts as a subject by responding to the surrounding entities. This model is used to propose a conceptual framework of information theory that can deal with both the qualitative (semantic) and quantitative aspects of the information involved in biological processes. Copyright © 2015 Elsevier Ltd. All rights reserved.

Using New Technologies: A Technology Transfer Guidebook. Version 02.00. 08

DTIC Science & Technology

1993-12-01

Barton (1990) and Pressman (1992), depend on the concept that improving your overall technology transfer process decreases the amount of time it takes to...Evolutionary Spiral Process Any enactment of the evolutionary spiral model (ESP) which is an adaptation of the basic spiral model pro- posed by Barry Boehm...Innovations in Organizations, 1989 CMU/SEI-89-TR-17, (also NTIS ADA211573). Pittsburgh, Pennsylvania: Software Engineering Institute. Boehm, Barry A

Reactive Radial Diffusion Model for the Aging/Sequestration Process

NASA Astrophysics Data System (ADS)

Ginn, T. R.; Basagaoglu, H.; McCoy, B. J.; Scow, K. M.

2001-12-01

A radial diffusion model has been formulated to simulate age-dependent bioavailability of chemical compounds to micro-organisms residing outside (and/or inside) the porous soil particles. Experimental findings in the literature indicate that the sequestration and reduction in bioavailability of contaminants are controlled presumably by the diffusion-limited sorption kinetics and the time-variant desorption process. Here we combine radial-diffusion mass transfer modeling with the exposure-time concept to generate mass-balance equations for the intra- and extra-particle concentrations. The model accomodates reversible sorption kinetics involving sorption time-dependence of the rate coefficients, distinct intra- and extra-particle biodegradation rates; and a dynamic mass interaction between the intra- and extra-particle concentrations arising from the radial diffusion concept. The model explicitly treats multiple particle classes distributed in size and chemical properties in a bulk aquifer or soil volume, which allows the simulation of the sequestration and bioavailability of contaminants in different particle size classes that have distinct diffusion, reaction, and aging properties.

Use of concept mapping in an undergraduate introductory exercise physiology course.

PubMed

Henige, Kim

2012-09-01

Physiology is often considered a challenging course for students. It is up to teachers to structure courses and create learning opportunities that will increase the chance of student success. In an undergraduate exercise physiology course, concept maps are assigned to help students actively process and organize information into manageable and meaningful chunks and to teach them to recognize the patterns and regularities of physiology. Students are first introduced to concept mapping with a commonly relatable nonphysiology concept and are then assigned a series of maps that become more and more complex. Students map the acute response to a drop in blood pressure, the causes of the acute increase in stroke volume during cardiorespiratory exercise, and the factors contributing to an increase in maximal O(2) consumption with cardiorespiratory endurance training. In the process, students draw the integrative nature of physiology, identify causal relationships, and learn about general models and core principles of physiology.

Doped Organic Transistors.

PubMed

Lüssem, Björn; Keum, Chang-Min; Kasemann, Daniel; Naab, Ben; Bao, Zhenan; Leo, Karl

2016-11-23

Organic field-effect transistors hold the promise of enabling low-cost and flexible electronics. Following its success in organic optoelectronics, the organic doping technology is also used increasingly in organic field-effect transistors. Doping not only increases device performance, but it also provides a way to fine-control the transistor behavior, to develop new transistor concepts, and even improve the stability of organic transistors. This Review summarizes the latest progress made in the understanding of the doping technology and its application to organic transistors. It presents the most successful doping models and an overview of the wide variety of materials used as dopants. Further, the influence of doping on charge transport in the most relevant polycrystalline organic semiconductors is reviewed, and a concise overview on the influence of doping on transistor behavior and performance is given. In particular, recent progress in the understanding of contact doping and channel doping is summarized.

Effects of Concept Mapping on Creativity in Photo Stories

ERIC Educational Resources Information Center

Simper, Natalie; Reeve, Richard; Kirby, J. R.

2016-01-01

This research tested the use of concept map planning to support the development of creativity in photo stories, hypothesizing that skills taught to support organization would improve creativity. Concept maps are a type of graphic organizer, used to represent an ordering of ideas with nodes and linking words that form propositional statements. They…

Are Abstract and Concrete Concepts Organized Differently? Evidence from the Blocked Translation Paradigm

ERIC Educational Resources Information Center

Zhang, Xiaohong; Han, Zaizhu; Bi, Yanchao

2013-01-01

Using the blocked-translation paradigm with healthy participants, we examined Crutch and Warrington's hypothesis that concrete and abstract concepts are organized by distinct principles: concrete concepts by semantic similarities and abstract ones by associations. In three experiments we constructed two types of experimental blocking (similar…

Alternative Conceptions about Micro-Organisms Are Influenced by Experiences with Disease in Children

ERIC Educational Resources Information Center

Prokop, Pavol; Fancovicová, Jana; Krajcovicová, Adriána

2016-01-01

Children's ideas concerning natural phenomena often differ from those of scientists, and these ideas are termed as alternative conceptions. The prevalence of alternative conceptions is highest among young children who possess less experience with the natural world as compared with adults. Children's ideas about micro-organisms are of special…

The evolution of concepts of vestibular peripheral information processing: toward the dynamic, adaptive, parallel processing macular model

NASA Technical Reports Server (NTRS)

Ross, Muriel D.

2003-01-01

In a letter to Robert Hooke, written on 5 February, 1675, Isaac Newton wrote "If I have seen further than certain other men it is by standing upon the shoulders of giants." In his context, Newton was referring to the work of Galileo and Kepler, who preceded him. However, every field has its own giants, those men and women who went before us and, often with few tools at their disposal, uncovered the facts that enabled later researchers to advance knowledge in a particular area. This review traces the history of the evolution of views from early giants in the field of vestibular research to modern concepts of vestibular organ organization and function. Emphasis will be placed on the mammalian maculae as peripheral processors of linear accelerations acting on the head. This review shows that early, correct findings were sometimes unfortunately disregarded, impeding later investigations into the structure and function of the vestibular organs. The central themes are that the macular organs are highly complex, dynamic, adaptive, distributed parallel processors of information, and that historical references can help us to understand our own place in advancing knowledge about their complicated structure and functions.

Simulation of hydrogen adsorption systems adopting the flow through cooling concept

DOE PAGES

Corgnale, Claudio; Hardy, Bruce; Chahine, Richard; ...

2014-10-13

Hydrogen storage systems based on adsorbent materials have the potential of achieving the U.S. Department of Energy (DOE) targets, especially in terms of gravimetric capacity. This paper deals with analysis of adsorption storage systems adopting the flow through cooling concept. By this approach the feeding hydrogen provides the needed cold to maintain the tank at low temperatures. Two adsorption systems have been examined and modeled adopting the Dubinin-Astakhov model, to see their performance under selected operating conditions. A first case has been analyzed, modeling a storage tank filled with carbon based material (namely MaxSorb®) and comparing the numerical outcomes withmore » the available experimental results for a 2.5 L tank. Under selected operating conditions (minimum inlet hydrogen temperature of approximately 100 K and maximum pressure on the order of 8.5 MPa) and adopting the flow through cooling concept the material shows a gravimetric capacity of about 5.7 %. A second case has been modeled, examining the same tank filled with metal organic framework material (MOF5®) under approximately the same conditions. The model shows that the latter material can achieve a (material) gravimetric capacity on the order of 11%, making the system potentially able to achieve the DOE 2017 target.« less

Nursing intellectual capital theory: operationalization and empirical validation of concepts.

PubMed

Covell, Christine L; Sidani, Souraya

2013-08-01

To present the operationalization of concepts in the nursing intellectual capital theory and the results of a methodological study aimed at empirically validating the concepts. The nursing intellectual capital theory proposes that the stocks of nursing knowledge in an organization are embedded in two concepts, nursing human capital and nursing structural capital. The theory also proposes that two concepts in the work environment, nurse staffing and employer support for nursing continuing professional development, influence nursing human capital. A cross-sectional design. A systematic three-step process was used to operationalize the concepts of the theory. In 2008, data were collected for 147 inpatient units from administrative departments and unit managers in 6 Canadian hospitals. Exploratory factor analyses were conducted to determine if the indicator variables accurately reflect their respective concepts. The proposed indicator variables collectively measured the nurse staffing concept. Three indicators were retained to construct nursing human capital: clinical expertise and experience concept. The nursing structural capital and employer support for nursing continuing professional development concepts were not validated empirically. The nurse staffing and the nursing human capital: clinical expertise and experience concepts will be brought forward for further model testing. Refinement for some of the indicator variables of the concepts is indicated. Additional research is required with different sources of data to confirm the findings. © 2012 Blackwell Publishing Ltd.

Persuasion Model and Its Evaluation Based on Positive Change Degree of Agent Emotion

NASA Astrophysics Data System (ADS)

Jinghua, Wu; Wenguang, Lu; Hailiang, Meng

For it can meet needs of negotiation among organizations take place in different time and place, and for it can make its course more rationality and result more ideal, persuasion based on agent can improve cooperation among organizations well. Integrated emotion change in agent persuasion can further bring agent advantage of artificial intelligence into play. Emotion of agent persuasion is classified, and the concept of positive change degree is given. Based on this, persuasion model based on positive change degree of agent emotion is constructed, which is explained clearly through an example. Finally, the method of relative evaluation is given, which is also verified through a calculation example.

Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization.

PubMed

Roeder, Ingo; Kamminga, Leonie M; Braesel, Katrin; Dontje, Bert; de Haan, Gerald; Loeffler, Markus

2005-01-15

Many current experimental results show the necessity of new conceptual approaches to understand hematopoietic stem cell organization. Recently, we proposed a novel theoretical concept and a corresponding quantitative model based on microenvironment-dependent stem cell plasticity. The objective of our present work is to subject this model to an experimental test for the situation of chimeric hematopoiesis. Investigating clonal competition processes in DBA/2-C57BL/6 mouse chimeras, we observed biphasic chimerism development with initially increasing but long-term declining DBA/2 contribution. These experimental results were used to select the parameters of the mathematical model. To validate the model beyond this specific situation, we fixed the obtained parameter configuration to simulate further experimental settings comprising variations of transplanted DBA/2-C57BL/6 proportions, secondary transplantations, and perturbation of stabilized chimeras by cytokine and cytotoxic treatment. We show that the proposed model is able to consistently describe the situation of chimeric hematopoiesis. Our results strongly support the view that the relative growth advantage of strain-specific stem cells is not a fixed cellular property but is sensitively dependent on the actual state of the entire system. We conclude that hematopoietic stem cell organization should be understood as a flexible, self-organized rather than a fixed, preprogrammed process.

Resilience: synthesis of concept analyses and contribution to nursing classifications.

PubMed

Caldeira, S; Timmins, F

2016-06-01

To synthetize elements of research on concept analyses of resilience; and to propose a definition of resilience to NANDA International (NANDA-I) and International Classification for Nursing Practice (ICNP(®) ). Nursing classifications represent nursing knowledge that is clinically relevant and in continuous development. Nursing is considered holistic and there is always the need to consider human responses to health and life processes. Continuously there are new and emerging concepts concerning humans and health that should be considered within the organization and delivery of health care as resilience. In March 2015, the authors performed a synthesis of the findings of research concept analysis research derived from a systematic literature search of electronic databases (PsycINFO, CINAHL and PubMed). Search terms used in the title were: 'resilience' AND 'analysis' AND 'concept'. Papers written in Portuguese or English were included. A total of 27 papers were identified and eight papers were included. Of these, seven papers used Walker & Avant's () model and one used Rodger's () model. Resilience emerged as a fundamental concept across the lifespan that is closely related to health and well-being. Resilience is a phenomenon of interest for nurses. Similar attributes, antecedents, consequents and definitions were synthesized into a new proposal of a definition of resilience. While some diagnoses related to resilience are classified in NANDA-I, the concept is not included in ICNP(®) . The inclusion of the concept into ICNP(®) and the update in NANDA-I is a contribution for nursing knowledge through education and for clinical practice, as this could promote the effectiveness of interventions in several contexts. © 2016 International Council of Nurses.

The inclusive workplace: an ecosystems approach to diversity management.

PubMed

Barak, M E

2000-07-01

This article's main argument is that organizations need to expand their notion of diversity to include not only the organization itself, but also the larger systems that constitute its environment. The concept of "the inclusive workplace," introduced here, refers to a work organization that is not only accepting and using the diversity of its own work force, but also is active in the community, participates in state and federal programs to include working poor people, and collaborates across cultural and national boundaries with a focus on global mutual interests. Using an ecosystems perspective, the article outlines a value-based model and a practice-based model of the inclusive workplace as they pertain to the different organizational levels, from the micro to the macro. Finally, implications for the social work profession are drawn with specific case examples for each system level.

Sustained Innovation Through Shared Capitalism and Democratic Governance

NASA Astrophysics Data System (ADS)

Beyster, M. A.; Blasi, J.; Sibilia, J.; Zebuchen, T.; Bowman, A.

The Foundation for Enterprise Development (FED) explores application of democratic representative governance models and structures for long-term interdisciplinary research, development and education to the concept of an organization that can sustain activity in support of interstellar travel in the 100-year timeframe, as outlined by the 100 Year StarshipTM. This paper titled, Sustained Innovation through Shared Capitalism and Democratic Governance , explores the roots of representative structures and organizations as long-lived success stories throughout history. Research, innovation, organizational structures and associated issues are explored to address the long-term focus required for development, both material and human. Impact investing vehicles are also explored as potential investment structures addressing the long-term horizon required by the organization. This paper provides an illustration, description and philosophical approach of this model as developed by the FED and our collaborators.

Making Riverscapes Real (Invited)

NASA Astrophysics Data System (ADS)

Marcus, A.; Carbonneau, P.; Fonstad, M. A.; Walther, S. C.

2009-12-01

The structure and function of rivers have long been characterized either by: (1) qualitative models such as the River Continuum Concept or Serial Discontinuity Concept which paint broad descriptive portraits of how river habitats and communities vary, or (2) quantitative models, such as Downstream Hydraulic Geometry, which rely on a limited number of measurements spread widely throughout a river basin. In contrast, Fausch et al. (2002) proposed applying landscape ecology methods to rivers to create “riverscapes.” Application of the riverscape concept requires information on the spatial distribution of organism-scale habitats throughout entire river systems. In practical terms, this means that researchers must replicate maps of local habitat continuously throughout entire rivers to document and predict total habitat availability, structure, and function. Likewise, information on time-dependent variations in these river habitats is necessary. Given these requirements, it is not surprising that the riverscape approach has largely remained a conceptual framework with limited practical application. Recent advances in remote sensing and desktop computing, however, make the riverscape concept more achievable from a mapping perspective. Remote sensing methods now enable sub-meter measurements of depth, water surface slope, grain size, biotypes, algae, and plants, as well as estimation of derived parameters such as velocity and stream power. Although significant obstacles remain to basin-extent sub-meter mapping of physical habitat, recent advances are overcoming these obstacles and allowing the riverscape concept to be put into use by different agencies - at least from a physical habitat perspective. More problematic to the riverscape approach, however, are two major issues that cannot be solved with technical solutions. First is the difficulty in acquiring maps of fauna, whether they be macroinvertebrates, fish, or microorganisms, at scales and spatial extents comparable to physical habitat data. Given that funding will not be available in most rivers to map organism distributions across all scales and locations, modeling of organism distributions over space and time will have to be an integral part of making riverscapes “real.” A second challenge is that existing quantitative and qualitative models do not capture or explain the multiple scales of spatial variability shown by continuous, high resolution maps of riverscapes. Riverscapes thus challenge our existing understanding of how rivers structure themselves and will force development of new paradigms. Absent these new paradigms, riverscape maps provide an information overload that scientists and managers have trouble conceptualizing and using. This paper presents examples of riverscape mapping from around the world, demonstrates ways in which the maps can be used, and discusses the fundamental ways in which multiscalar, basin-extent riverscapes challenge our present understanding of river structure and function.

Developing energy and momentum conceptual survey (EMCS) with four-tier diagnostic test items

NASA Astrophysics Data System (ADS)

Afif, Nur Faadhilah; Nugraha, Muhammad Gina; Samsudin, Achmad

2017-05-01

Students' conceptions of work and energy are important to support the learning process in the classroom. For that reason, a diagnostic test instrument is needed to diagnose students' conception of work and energy. As a result, the researcher decided to develop Energy and Momentum Conceptual Survey (EMCS) instrument test into four-tier test diagnostic items. The purpose of this research is organized as the first step of four-tier test-formatted EMCS development as one of diagnostic test instruments on work and Energy. The research method used the 4D model (Defining, Designing, Developing and Disseminating). The instrument developed has been tested to 39 students in one of Senior High Schools. The resulting research showed that four-tier test-formatted EMCS is able to diagnose students' conception level of work and energy concept. It can be concluded that the development of four-tier test-formatted EMCS is one of potential diagnostic test instruments that able to obtain the category of students who understand concepts, misconceptions and do not understand about Work and Energy concept at all.

Organizational models of educational technology in U.S. and Canadian medical schools.

PubMed

Souza, Kevin H; Kamin, Carol; O'Sullivan, Patricia; Moses, Anna; Heestand, Diane

2008-07-01

To examine the organizational structure of educational technology units within U.S. and Canadian medical schools in order to (1) identify organization models that support educational technology, (2) describe key attributes of these models, and (3) discuss the strengths and challenges associated with these models. The authors distributed a survey to 88 schools that had previously provided information on their educational technology services and infrastructure. The authors developed the survey through a series of pilots and, then, from the data for each respondent school, created concept maps, which were used to identify organizational models. The authors conducted analyses to determine differences among models. The authors coded the comments about organizational models and identified themes. The authors received adequate data for analysis from 61 schools (69%). Four models for educational technology organizations emerged: (1) centralized units located in the school of medicine, (2) centralized units located at the health science center, (3) centralized units at the comprehensive university, and (4) no centralized unit (Dispersed Model). The majority (75%) of schools relied on some type of centralized organization. Whereas few organization attributes proved to be statistically significant, the centralized models have more resources devoted to educational technology and a closer alignment with the academic mission than the Dispersed Model. Medical schools primarily use central models. The authors recommend that schools structuring their educational technology resources consider exploration of a central model because of its focused use of resources to improve teaching and learning.

Effects of the use of thematic organizers in conjunction with concept mapping on learning, misconceptions, and retention in middle school science class

NASA Astrophysics Data System (ADS)

Keown, Sandra L.

This study was devised to determine effects of the use of interactive thematic organizers and concept maps in middle school science classes during a unit study on minerals. The design, a pretest-posttest control group, consisted of matched groups (three experimental groups and one comparison group). It also included a student survey assessing qualitative aspects of the investigation. The 67 6th-grade students and one science teacher who participated in the study were from an independent K-12 school. Students represented a normal, well-distributed range of abilities. Group I (control) proceeded with their usual method of studying a unit---reading aloud the text and answering workbook questions. Group II worked with interactive thematic organizers, designed to activate prior knowledge and help students make inferences about target concepts in three treatments. Group III created three interactive concept maps, which represented both understandings and misconceptions. Concept maps were reviewed and repaired as students completed each treatment. Group IV participated in both thematic organizer and concept map treatments. Statistical analyses were determined through a pretest and a delayed recall posttest essay for all four groups. Two scores were assigned---one quantitative raw score of correct explicit answers and one rubric score based on the quality of interpretive responses. Group II also received scores for thematic organizer responses. Group III received rubric scores for concept maps. Group IV received all possible scores. Paired t-tests reported comparisons of scores across the treatment groups. A linear regression indicated whether or not concept map misconceptions affected posttest scores. Finally, an ANCOVA reported statistical significance across the four treatment groups. Findings of data analysis indicated statistically significant improvement in posttest scores among students in the three experimental groups. Students who participated in both treatments represented the highest scores among the four groups. Results of the ANCOVA indicated there was statistically significant difference in scores among the four treatments. Recommendations were made to further investigate development of interactive thematic organizers with student-chosen hyperlinks to concepts, as well as a recommendation that researchers investigate teacher understandings of interpretive purpose and form in the creation of thematic organizers.

Designing ternary blend bulk heterojunction solar cells with reduced carrier recombination and a fill factor of 77%

NASA Astrophysics Data System (ADS)

Gasparini, Nicola; Jiao, Xuechen; Heumueller, Thomas; Baran, Derya; Matt, Gebhard J.; Fladischer, Stefanie; Spiecker, Erdmann; Ade, Harald; Brabec, Christoph J.; Ameri, Tayebeh

2016-09-01

In recent years the concept of ternary blend bulk heterojunction (BHJ) solar cells based on organic semiconductors has been widely used to achieve a better match to the solar irradiance spectrum, and power conversion efficiencies beyond 10% have been reported. However, the fill factor of organic solar cells is still limited by the competition between recombination and extraction of free charges. Here, we design advanced material composites leading to a high fill factor of 77% in ternary blends, thus demonstrating how the recombination thresholds can be overcome. Extending beyond the typical sensitization concept, we add a highly ordered polymer that, in addition to enhanced absorption, overcomes limits predicted by classical recombination models. An effective charge transfer from the disordered host system onto the highly ordered sensitizer effectively avoids traps of the host matrix and features an almost ideal recombination behaviour.

[Theoretical and conceptual contribution to evaluative research in health surveillance context].

PubMed

Arreaza, Antônio Luis Vicente; de Moraes, José Cássio

2010-08-01

Initially this article revises some of the conceptual and operational elements on evaluative research by gathering knowledge and action fields on public health practices. Such concepts are taken according to a wider conception of quality. Then, the article intends to arrange a theoretical model design considering the proposition for implementation of health surveillance actionsAn image-objective definition of organization and integration of health polices and practices based on hierarchic and local logic also take place. Finally, becomings and challenges around the theory in the health evaluation field turn to be the aim of our reflection in order to enable the production of knowledge and approaches to construct logic models which reveals the complexity of interventionist objects as well as its transforming nature of social practices.

Do the Modern Neurosciences Call for a New Model of Organizational Cognition?

ERIC Educational Resources Information Center

Seni, Dan Alexander

2012-01-01

Our purpose in this paper is to try to make a significant contribution to the analysis of cognitive capabilities of the organization of active social systems such as the business enterprise by re-examining the concepts of organizational intelligence, organizational memory and organizational learning in light of the findings of modern neuroscience.…

Illustrating Concepts in Physical Organic Chemistry with 3D Printed Orbitals

ERIC Educational Resources Information Center

Robertson, Michael J.; Jorgensen, William L.

2015-01-01

Orbital theory provides a powerful tool for rationalizing and understanding many phenomena in chemistry. In most introductory chemistry courses, students are introduced to atomic and molecular orbitals in the form of two-dimensional drawings. In this work, we describe a general method for producing 3D printing files of orbital models that can be…

Elementary Anatomy: Activities Designed to Teach Preschool Children about the Human Body

ERIC Educational Resources Information Center

Raven, Sara

2016-01-01

Studies show that children may not be able to conceptualize some of the topics associated with anatomy, including internal organs and involuntary muscles, because the concepts are too abstract and are not easily visualized. Thus, this article presents activities that incorporate a variety of models and hands-on activities designed to provide…

In Support of Coaching Models of Management and Leadership: A Comparative Study of Empirically Derived Managerial Coaching/Facilitating Learning Behaviors

ERIC Educational Resources Information Center

Hamlin, Bob; Ellinger, Andrea D.; Beattie, Rona S.

2004-01-01

The concept of managers assuming developmental roles such as coaches and learning facilitators has gained considerable attention in recent years as organizations seek to leverage learning by creating infrastructures that foster employee learning and development. Despite the increased focus on coaching, the literature base remains atheoretical.…

Using an "Open Approach" to Create a New, Innovative Higher Education Model

ERIC Educational Resources Information Center

Huggins, Susan; Smith, Peter

2015-01-01

Navigating learning, formal or informal, can be overwhelming, confusing, and impersonal. With more options than ever, the process of deciding what, where, and when can be overwhelming to a learner. The concept of Open College at Kaplan University (OC@KU) was to bring organization, purpose, and personalization of learning caused by vast resources…

Synthesizing Soft Systems Methodology and Human Performance Technology

ERIC Educational Resources Information Center

Scott, Glen; Winiecki, Donald J.

2012-01-01

Human performance technology (HPT), like other concepts, models, and frameworks that we use to describe the world in which we live and the way we organize ourselves to accomplish valuable activities, is built from paradigms that were fresh and relevant at the time it was conceived and from the fields of study from which it grew. However, when the…

Biomonitors: Practice and Concepts

DTIC Science & Technology

1986-01-01

A.A. Benson. ACKNOWLEDGEMENTS Petroleum hydrocarbons : uptake and discharge by the marine mussel, Mytilus edulis. Science supported by the Office of...Simkiss, K., M. Taylor & A.Z. Mason. Metal 11. Spacie, A. & J.L. Hamelink. Alternative models detoxification and bioaccumulation in molluscs . % for... petroleum hydrocarbons : Accumulation and Marine Ecology Progress Series 1980 3, 257- biotransformation in marine organisms. In: T6= Effects of

A Novel Conceptual Model of Environmental Communal Education: Content Analysis Based on Distance Education Approach

ERIC Educational Resources Information Center

Hafezi, Soheila; Shobeiri, Seyed Mohammad; Sarmadi, Mohammad Reza; Ebadi, Abbas

2013-01-01

Environmental education as a learning process increases people's knowledge and awareness about the environment. Although in some countries, the Environmental Communal Education (ECE) is the core of the environmental education by formal and informal organizations and groups, but, it has not clarified the meaning of the ECE's concept. Therefore the…

A general method for radio spectrum efficiency defining

NASA Astrophysics Data System (ADS)

Ramadanovic, Ljubomir M.

1986-08-01

A general method for radio spectrum efficiency defining is proposed. Although simple it can be applied to various radio services. The concept of spectral elements, as information carriers, is introduced to enable the organization of larger spectral spaces - radio network models - characteristic for a particular radio network. The method is applied to some radio network models, concerning cellular radio telephone systems and digital radio relay systems, to verify its unified approach capability. All discussed radio services operate continuously.

The "spare parts person"? Conceptions of the human body and their implications for public attitudes towards organ donation and organ sale.

PubMed

Schweda, Mark; Schicktanz, Silke

2009-02-18

The increasing debate on financial incentives for organ donation raises concerns about a "commodification of the human body". Philosophical-ethical stances on this development depend on assumptions concerning the body and how people think about it. In our qualitative empirical study we analyze public attitudes towards organ donation in their specific relation to conceptions of the human body in four European countries (Cyprus, Germany, the Netherlands and Sweden). This approach aims at a more context-sensitive picture of what "commodification of the body" can mean in concrete clinical decisions concerning organ donation. We find that moral intuitions concerning organ donation are rooted in various conceptions of the human body and its relation to the self: a) the body as a mechanical object owned by the self, b) the body as a part of a higher order embodying the self, and c) the body as a hierarchy of organs constitutive of the self. The language of commodification is much too simple to capture what is at stake in everyday life intuitions about organ donation and organ sale. We discuss how the plurality of underlying body-self conceptions can be taken into account in the ethical debate, pointing out consequences for an anthropologically informed approach and for a liberal perspective.

Computer-Based Tools for Inquiry in Undergraduate Classrooms: Results from the VGEE

NASA Astrophysics Data System (ADS)

Pandya, R. E.; Bramer, D. J.; Elliott, D.; Hay, K. E.; Mallaiahgari, L.; Marlino, M. R.; Middleton, D.; Ramamurhty, M. K.; Scheitlin, T.; Weingroff, M.; Wilhelmson, R.; Yoder, J.

2002-05-01

The Visual Geophysical Exploration Environment (VGEE) is a suite of computer-based tools designed to help learners connect observable, large-scale geophysical phenomena to underlying physical principles. Technologically, this connection is mediated by java-based interactive tools: a multi-dimensional visualization environment, authentic scientific data-sets, concept models that illustrate fundamental physical principles, and an interactive web-based work management system for archiving and evaluating learners' progress. Our preliminary investigations showed, however, that the tools alone are not sufficient to empower undergraduate learners; learners have trouble in organizing inquiry and using the visualization tools effectively. To address these issues, the VGEE includes an inquiry strategy and scaffolding activities that are similar to strategies used successfully in K-12 classrooms. The strategy is organized around the steps: identify, relate, explain, and integrate. In the first step, students construct visualizations from data to try to identify salient features of a particular phenomenon. They compare their previous conceptions of a phenomenon to the data examine their current knowledge and motivate investigation. Next, students use the multivariable functionality of the visualization environment to relate the different features they identified. Explain moves the learner temporarily outside the visualization to the concept models, where they explore fundamental physical principles. Finally, in integrate, learners use these fundamental principles within the visualization environment by literally placing the concept model within the visualization environment as a probe and watching it respond to larger-scale patterns. This capability, unique to the VGEE, addresses the disconnect that novice learners often experience between fundamental physics and observable phenomena. It also allows learners the opportunity to reflect on and refine their knowledge as well as anchor it within a context for long-term retention. We are implementing the VGEE in one of two otherwise identical entry-level atmospheric courses. In addition to comparing student learning and attitudes in the two courses, we are analyzing student participation with the VGEE to evaluate the effectiveness and usability of the VGEE. In particular, we seek to identify the scaffolding students need to construct physically meaningful multi-dimensional visualizations, and evaluate the effectiveness of the visualization-embedded concept-models in addressing inert knowledge. We will also examine the utility of the inquiry strategy in developing content knowledge, process-of-science knowledge, and discipline-specific investigatory skills. Our presentation will include video examples of student use to illustrate our findings.

Practical example of game theory application for production route selection

NASA Astrophysics Data System (ADS)

Olender, M.; Krenczyk, D.

2017-08-01

The opportunity which opens before manufacturers on the dynamic market, especially before those from the sector of the small and medium-sized enterprises, is associated with the use of the virtual organizations concept. The planning stage of such organizations could be based on supporting decision-making tasks using the tools and formalisms taken from the game theory. In the paper the model of the virtual manufacturing network, along with the practical example of decision-making situation as two person game and the decision strategies with an analysis of calculation results are presented.

A conceptual framework for intelligent real-time information processing

NASA Technical Reports Server (NTRS)

Schudy, Robert

1987-01-01

By combining artificial intelligence concepts with the human information processing model of Rasmussen, a conceptual framework was developed for real time artificial intelligence systems which provides a foundation for system organization, control and validation. The approach is based on the description of system processing terms of an abstraction hierarchy of states of knowledge. The states of knowledge are organized along one dimension which corresponds to the extent to which the concepts are expressed in terms of the system inouts or in terms of the system response. Thus organized, the useful states form a generally triangular shape with the sensors and effectors forming the lower two vertices and the full evaluated set of courses of action the apex. Within the triangle boundaries are numerous processing paths which shortcut the detailed processing, by connecting incomplete levels of analysis to partially defined responses. Shortcuts at different levels of abstraction include reflexes, sensory motor control, rule based behavior, and satisficing. This approach was used in the design of a real time tactical decision aiding system, and in defining an intelligent aiding system for transport pilots.

Knowledge of the Brain Death Concept Among the Population of Havana, Cuba.

PubMed

Ríos, A; López-Navas, A I; Sánchez, Á; Martinez-Alarcon, L; Ayala, M A; Garrido, G; Sebastián, M J; Ramis, G; Abdo-Cuza, A; Hernández, A; Ramírez, P; Parrilla, P

2018-03-01

One of the main reasons against organ donation is the fear of apparent death due to ignorance of the brain death concept. Our aim was to assess knowledge about and acceptance of the brain death concept among the population of Havana, Cuba. The population screened, stratified by gender and age, included those >15 years old and living in Havana, Cuba. The appraisal tool utilized was a questionnaire on attitude toward organ donation ("PCID-DTO Ríos"). A random selection of individuals were surveyed according to the stratification. Cuba's census data were used. The participation was anonymized and self-administered. The verbal consent of participants was provided. There were 920 respondents: 31% (n = 282) knew the concept of brain death and accepted it; 57% (n = 529) did not; and 12% (n = 109) had a misperception, or did not accept brain death as a person's death. Those who knew and accepted the concept had a more favorable attitude toward their own organ donation after death (85% vs 61%; P < .001). The psychosocial factors related to the knowledge of brain death concept were: the gender (P = .002), to make up for speaking at a family level about the organ transplant (P < .001), the couple's opinion about the organ donation (P < .001) and the religion (P < .001). The brain death concept is not well understood in the population of Havana, Cuba. Copyright © 2017 Elsevier Inc. All rights reserved.

Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes

PubMed Central

Justice, Jamie; Miller, Jordan D.; Newman, John C.; Hashmi, Shahrukh K.; Halter, Jeffrey; Austad, Steve N.; Barzilai, Nir

2016-01-01

Therapies targeted at fundamental processes of aging may hold great promise for enhancing the health of a wide population by delaying or preventing a range of age-related diseases and conditions—a concept dubbed the “geroscience hypothesis.” Early, proof-of-concept clinical trials will be a key step in the translation of therapies emerging from model organism and preclinical studies into clinical practice. This article summarizes the outcomes of an international meeting partly funded through the NIH R24 Geroscience Network, whose purpose was to generate concepts and frameworks for early, proof-of-concept clinical trials for therapeutic interventions that target fundamental processes of aging. The goals of proof-of-concept trials include generating preliminary signals of efficacy in an aging-related disease or outcome that will reduce the risk of conducting larger trials, contributing data and biological samples to support larger-scale research by strategic networks, and furthering a dialogue with regulatory agencies on appropriate registration indications. We describe three frameworks for proof-of-concept trials that target age-related chronic diseases, geriatric syndromes, or resilience to stressors. We propose strategic infrastructure and shared resources that could accelerate development of therapies that target fundamental aging processes. PMID:27535966

Role stress amongst nurses at the workplace: concept analysis.

PubMed

Riahi, Sanaz

2011-09-01

The present study explicates the concept of role stress amongst nurses through an analysis adopted from Walker and Avant; Strategies for Theory Construction in Nursing, 4th edn, Prentice Hall, New Jersey, NY. Role stress has become a significant problem amongst nurses and has created much distress leading to burnout among many in the nursing profession. It is significant to analyse the concept of role stress and its relative attributes and consequences, in order to recognize the necessary antecedents needed to create better conditions for nurses at the workplace. A modified method developed by Walker and Avant was used for this concept analysis. A model representing the concept of role stress was developed through careful consideration of the attributes, consequences, antecedents and empirical referents of role stress. The concept analysis of role stress among nurses at the workplace recognized the vulnerability of the nursing discipline towards burnout and distress in general. It is critical to be aware of the current state of health care and note the increased workload created for nurses. Nurses are at a greater vulnerability for role stress, making it imperative for health care organizations to critically evaluate and establish preventative measures for the concept of role stress. 2011 Blackwell Publishing Ltd.

Understanding Global Change (UGC) as a Unifying Conceptual Framework for Teaching Ecology: Using UGC in a High School Biology Program to Integrate Earth Science and Biology, and to Demonstrate the Value of Modeling Global Systems in Promoting Conceptual Learning

NASA Astrophysics Data System (ADS)

Levine, J.; Bean, J. R.

2017-12-01

Global change science is ideal for NGSS-informed teaching, but presents a serious challenge to K-12 educators because it is complex and interdisciplinary- combining earth science, biology, chemistry, and physics. Global systems are themselves complex. Adding anthropogenic influences on those systems creates a formidable list of topics - greenhouse effect, climate change, nitrogen enrichment, introduced species, land-use change among them - which are often presented as a disconnected "laundry list" of "facts." This complexity, combined with public and mass-media scientific illiteracy, leaves global change science vulnerable to misrepresentation and politicization, creating additional challenges to teachers in public schools. Ample stand-alone, one-off, online resources, many of them excellent, are (to date) underutilized by teachers in the high school science course taken by most students: biology. The Understanding Global Change project (UGC) from the UC Berkeley Museum of Paleontology has created a conceptual framework that organizes, connects, and explains global systems, human and non-human drivers of change in those systems, and measurable changes in those systems. This organization and framework employ core ideas, crosscutting concepts, structure/function relationships, and system models in a unique format that facilitates authentic understanding, rather than memorization. This system serves as an organizing framework for the entire ecology unit of a forthcoming mainstream high school biology program. The UGC system model is introduced up front with its core informational graphic. The model is elaborated, step by step, by adding concepts and processes as they are introduced and explained in each chapter. The informational graphic is thus used in several ways: to organize material as it is presented, to summarize topics in each chapter and put them in perspective, and for review and critical thinking exercises that supplement the usual end-of-chapter lists of key terms.

Experience of Time Passage:. Phenomenology, Psychophysics, and Biophysical Modelling

NASA Astrophysics Data System (ADS)

Wackermann, Jiří

2005-10-01

The experience of time's passing appears, from the 1st person perspective, to be a primordial subjective experience, seemingly inaccessible to the 3rd person accounts of time perception (psychophysics, cognitive psychology). In our analysis of the `dual klepsydra' model of reproduction of temporal durations, time passage occurs as a cognitive construct, based upon more elementary (`proto-cognitive') function of the psychophysical organism. This conclusion contradicts the common concepts of `subjective' or `psychological' time as readings of an `internal clock'. Our study shows how phenomenological, experimental and modelling approaches can be fruitfully combined.

The significance of levels of organization for scientific research: A heuristic approach.

PubMed

Brooks, Daniel S; Eronen, Markus I

2018-04-10

The concept of 'levels of organization' has come under fire recently as being useless for scientific and philosophical purposes. In this paper, we show that 'levels' is actually a remarkably resilient and constructive conceptual tool that can be, and in fact is, used for a variety of purposes. To this effect, we articulate an account of the importance of the levels concept seen in light of its status as a major organizing concept of biology. We argue that the usefulness of 'levels' is best seen in the heuristic contributions the concept makes to treating and structuring scientific problems. We illustrate this with two examples from biological research. Copyright © 2018. Published by Elsevier Ltd.

Administrator self-ratings of organization capacity and performance of healthy community development projects in Taiwan.

PubMed

Chen, Ching-Min; Hong, Mei-Chu; Hsu, Yu-Hsien

2007-01-01

To examine the relationship between the capacities of various community organizations and their performance scores for healthy community development. This cross-sectional study was conducted by examining all community organizations involved in the Taiwan national healthy community development project. Of 213 administrators contacted, 195 (a return rate of 91.6%) completed a self-administered questionnaire between October and November 2003. The research instrument was self-developed and based on the Donabedian model. It examined the capacity of the community organizations and their performance in developing a healthy community. The average overall healthy community development performance score was 5.0 on a 7-point semantic differential scale, with the structure variable rated as the lowest among the 3 subscales. Community organization capacities in the areas of funding, resources committed, citizen participation, and certain aspects of organizational leadership were found to be significantly related to healthy community development performance. Each of the regression models showed a different set of capacities for the community organization domains and explained between 25% and 33% of the variance in performance. The study validates the theoretical relationships among the concepts identified in the Donabedian model. Nursing interventions tailored to enhance resident citizen participation in order to promote community coalitions are strongly supported.

The Organization for Economic Cooperation and Development: Functional Literacy and Corporate Agendas.

ERIC Educational Resources Information Center

Hyslop-Margison, Emery J.; Margison, Judith Ann

This paper examines the conception of functional literacy advanced by the Organization for Economic Cooperation and Development (OECD), a 29-member organization of leading industrialized countries, as part of its 1994 International Adult Literacy Survey (IALS). The paper suggests that embedded within this conception of literacy and the discourse…

Organization of Concepts Relevant to Emotions and Their Regulation during Test Taking.

ERIC Educational Resources Information Center

Schutz, Paul A.; Davis, Heather A.; Schwanenflugel, Paula J.

2002-01-01

Studied college students' organization of concepts related to emotions and their regulation during test taking and whether students with test anxiety have a different conceptual organization about test taking. Results with 78 and 76 students show that for students with low and moderate test anxiety, the organizational scheme for the selected…

Organizational health in health organizations: towards a conceptualization.

PubMed

Orvik, Arne; Axelsson, Runo

2012-12-01

This article is introducing a new concept of organizational health and discussing its possible implications for health organizations and health management. The concept is developed against the background of New Public Management, which has coincided with increasing workplace health problems in health organizations. It is based on research mainly in health promotion and health management. Organizational health is defined in terms of how an organization is able to deal with the tensions of diverse and competing values. This requires a dialectical perspective, integration as well as disintegration, and a tricultural approach to value tensions. The concept of organizational health is pointing towards an inverse value pyramid and a hybrid- and value-based form of management in health organizations. An application of this concept may clarify competing values and help managers to deal with the value tensions underlying workplace health problems on an organizational as well as an individual and group level. More empirical research is required, however, to link more closely the different aspects of organizational health in health organizations. © 2012 The Authors. Scandinavian Journal of Caring Sciences © 2012 Nordic College of Caring Science.

A meta-ethnography of patients' experiences of chronic pelvic pain: struggling to construct chronic pelvic pain as 'real'.

PubMed

Toye, Francine; Seers, Kate; Barker, Karen

2014-12-01

To review systematically and integrate the findings of qualitative research to increase our understanding of patients' experiences of chronic pelvic pain. Chronic pelvic pain is a prevalent pain condition with a high disease burden for men and women. Its multifactorial nature makes it challenging for clinicians and patients. Synthesis of qualitative research using meta-ethnography. Five electronic bibliographic databases from inception until March 2014 supplemented by citation tracking. Of 488 papers retrieved, 32 met the review aim. Central to meta-ethnography is identifying 'concepts' and developing a conceptual model through constant comparison. Concepts are the primary data of meta-ethnography. Two team members read each paper to identify and collaboratively describe the concepts. We next compared concepts across studies and organized them into categories with shared meaning. Finally, we developed a conceptual model, or line of argument, to explain the conceptual categories. Our findings incorporate the following categories into a conceptual model: relentless and overwhelming pain; threat to self; unpredictability, struggle to construct pain as normal or pathological; a culture of secrecy; validation by diagnosis; ambiguous experience of health care; elevation of experiential knowledge and embodiment of knowledge through a community. The innovation of our model is to demonstrate, for the first time, the central struggle to construct 'pathological' vs. 'normal' chronic pelvic pain, a struggle that is exacerbated by a culture of secrecy. More research is needed to explore men's experience and to compare this with women's experience. © 2014 John Wiley & Sons Ltd.

Cross-cultural undergraduate medical education in North America: theoretical concepts and educational approaches.

PubMed

Reitmanova, Sylvia

2011-04-01

Cross-cultural undergraduate medical education in North America lacks conceptual clarity. Consequently, school curricula are unsystematic, nonuniform, and fragmented. This article provides a literature review about available conceptual models of cross-cultural medical education. The clarification of these models may inform the development of effective educational programs to enable students to provide better quality care to patients from diverse sociocultural backgrounds. The approaches to cross-cultural health education can be organized under the rubric of two specific conceptual models: cultural competence and critical culturalism. The variation in the conception of culture adopted in these two models results in differences in all curricular components: learning outcomes, content, educational strategies, teaching methods, student assessment, and program evaluation. Medical schools could benefit from more theoretical guidance on the learning outcomes, content, and educational strategies provided to them by governing and licensing bodies. More student assessments and program evaluations are needed in order to appraise the effectiveness of cross-cultural undergraduate medical education.

Plants in silico: why, why now and what?--an integrative platform for plant systems biology research.

PubMed

Zhu, Xin-Guang; Lynch, Jonathan P; LeBauer, David S; Millar, Andrew J; Stitt, Mark; Long, Stephen P

2016-05-01

A paradigm shift is needed and timely in moving plant modelling from largely isolated efforts to a connected community endeavour that can take full advantage of advances in computer science and in mechanistic understanding of plant processes. Plants in silico (Psi) envisions a digital representation of layered dynamic modules, linking from gene networks and metabolic pathways through to cellular organization, tissue, organ and whole plant development, together with resource capture and use efficiency in dynamic competitive environments, ultimately allowing a mechanistically rich simulation of the plant or of a community of plants in silico. The concept is to integrate models or modules from different layers of organization spanning from genome to phenome to ecosystem in a modular framework allowing the use of modules of varying mechanistic detail representing the same biological process. Developments in high-performance computing, functional knowledge of plants, the internet and open-source version controlled software make achieving the concept realistic. Open source will enhance collaboration and move towards testing and consensus on quantitative theoretical frameworks. Importantly, Psi provides a quantitative knowledge framework where the implications of a discovery at one level, for example, single gene function or developmental response, can be examined at the whole plant or even crop and natural ecosystem levels. © 2015 The Authors Plant, Cell & Environment Published by John Wiley & Sons Ltd.

The Role of Cognitive Organizers in the Facilitation of Concept Learning in Elementary School Science.

ERIC Educational Resources Information Center

Schulz, Richard William

Studied was the effect of advance organizers, as defined by Ausubel, on the learning of concepts in science. Sixth grade classes studied two sequences of major concept-centered learning tasks developed by the investigator. The first had 12 lessons about energy forms and transformations; the second had five about photosynthesis and respiration as…

A Time Sequence-Oriented Concept Map Approach to Developing Educational Computer Games for History Courses

ERIC Educational Resources Information Center

Chu, Hui-Chun; Yang, Kai-Hsiang; Chen, Jing-Hong

2015-01-01

Concept maps have been recognized as an effective tool for students to organize their knowledge; however, in history courses, it is important for students to learn and organize historical events according to the time of their occurrence. Therefore, in this study, a time sequence-oriented concept map approach is proposed for developing a game-based…

Reference Model for Performance Management in Service-Oriented Virtual Organization Breeding Environments

NASA Astrophysics Data System (ADS)

Paszkiewicz, Zbigniew; Picard, Willy

Performance management (PM) is a key function of virtual organization (VO) management. A large set of PM indicators has been proposed and evaluated within the context of virtual breeding environments (VBEs). However, it is currently difficult to describe and select suitable PM indicators because of the lack of a common vocabulary and taxonomies of PM indicators. Therefore, there is a need for a framework unifying concepts in the domain of VO PM. In this paper, a reference model for VO PM is presented in the context of service-oriented VBEs. In the proposed reference model, both a set of terms that could be used to describe key performance indicators, and a set of taxonomies reflecting various aspects of PM are proposed. The proposed reference model is a first attempt and a work in progress that should not be supposed exhaustive.

Emergent structure-function relations in emphysema and asthma.

PubMed

Winkler, Tilo; Suki, Béla

2011-01-01

Structure-function relationships in the respiratory system are often a result of the emergence of self-organized patterns or behaviors that are characteristic of certain respiratory diseases. Proper description of such self-organized behavior requires network models that include nonlinear interactions among different parts of the system. This review focuses on 2 models that exhibit self-organized behavior: a network model of the lung parenchyma during the progression of emphysema that is driven by mechanical force-induced breakdown, and an integrative model of bronchoconstriction in asthma that describes interactions among airways within the bronchial tree. Both models suggest that the transition from normal to pathologic states is a nonlinear process that includes a tipping point beyond which interactions among the system components are reinforced by positive feedback, further promoting the progression of pathologic changes. In emphysema, the progressive destruction of tissue is irreversible, while in asthma, it is possible to recover from a severe bronchoconstriction. These concepts may have implications for pulmonary medicine. Specifically, we suggest that structure-function relationships emerging from network behavior across multiple scales should be taken into account when the efficacy of novel treatments or drug therapy is evaluated. Multiscale, computational, network models will play a major role in this endeavor.

Temporal and spatial variability of soil biological activity at European scale

NASA Astrophysics Data System (ADS)

Mallast, Janine; Rühlmann, Jörg

2015-04-01

The CATCH-C project aims to identify and improve the farm-compatibility of Soil Management Practices including to promote productivity, climate change mitigation and soil quality. The focus of this work concentrates on turnover conditions for soil organic matter (SOM). SOM is fundamental for the maintenance of quality and functions of soils while SOM storage is attributed a great importance in terms of climate change mitigation. The turnover conditions depend on soil biological activity characterized by climate and soil properties. Soil biological activity was investigated using two model concepts: a) Re_clim parameter within the ICBM (Introductory Carbon Balance Model) (Andrén & Kätterer 1997) states a climatic factor summarizing soil water storage and soil temperature and its influence on soil biological activity. b) BAT (biological active time) approach derived from model CANDY (CArbon and Nitrogen Dynamic) (Franko & Oelschlägel 1995) expresses the variation of soil moisture, soil temperature and soil aeration as a time scale and an indicator of biological activity for soil organic matter (SOM) turnover. During an earlier stage both model concepts, Re_clim and BAT, were applied based on a monthly data to assess spatial variability of turnover conditions across Europe. This hampers the investigation of temporal variability (e.g. intra-annual). The improved stage integrates daily data of more than 350 weather stations across Europe presented by Klein Tank et al. (2002). All time series data (temperature, precipitation and potential evapotranspiration and soil texture derived from the European Soil Database (JRC 2006)), are used to calculate soil biological activity in the arable layer. The resulting BAT and Re_clim values were spatio-temporal investigated. While "temporal" refers to a long-term trend analysis, "spatial" includes the investigation of soil biological activity variability per environmental zone (ENZ, Metzger et al. 2005 representing similar conditions for precipitation, temperature and relief) to identify ranges and hence turnover conditions for each ENZ. We will discuss the analyzed results of both concepts to assess SOM turnover conditions across Europe for historical weather data and for Spain focusing on climate scenarios. Both concepts help to separate different turnover activities and to indicate organic matter input in order to maintain the given SOM. The assessment could provide recommendations for adaptations of soil management practices. CATCH-C is funded within the 7th Framework Programme for Research, Technological Development and Demonstration, Theme 2 - Biotechnologies, Agriculture & Food (Grant Agreement N° 289782).

Concept mapping One-Carbon Metabolism to model future ontologies for nutrient-gene-phenotype interactions.

PubMed

Joslin, A C; Green, R; German, J B; Lange, M C

2014-09-01

Advances in the development of bioinformatic tools continue to improve investigators' ability to interrogate, organize, and derive knowledge from large amounts of heterogeneous information. These tools often require advanced technical skills not possessed by life scientists. User-friendly, low-barrier-to-entry methods of visualizing nutrigenomics information are yet to be developed. We utilized concept mapping software from the Institute for Human and Machine Cognition to create a conceptual model of diet and health-related data that provides a foundation for future nutrigenomics ontologies describing published nutrient-gene/polymorphism-phenotype data. In this model, maps containing phenotype, nutrient, gene product, and genetic polymorphism interactions are visualized as triples of two concepts linked together by a linking phrase. These triples, or "knowledge propositions," contextualize aggregated data and information into easy-to-read knowledge maps. Maps of these triples enable visualization of genes spanning the One-Carbon Metabolism (OCM) pathway, their sequence variants, and multiple literature-mined associations including concepts relevant to nutrition, phenotypes, and health. The concept map development process documents the incongruity of information derived from pathway databases versus literature resources. This conceptual model highlights the importance of incorporating information about genes in upstream pathways that provide substrates, as well as downstream pathways that utilize products of the pathway under investigation, in this case OCM. Other genes and their polymorphisms, such as TCN2 and FUT2, although not directly involved in OCM, potentially alter OCM pathway functionality. These upstream gene products regulate substrates such as B12. Constellations of polymorphisms affecting the functionality of genes along OCM, together with substrate and cofactor availability, may impact resultant phenotypes. These conceptual maps provide a foundational framework for development of nutrient-gene/polymorphism-phenotype ontologies and systems visualization.

Concepts of health and well-being in managers: An organizational study

PubMed Central

Boness, Christian

2011-01-01

Global changes and new managerial challenges require new concepts of health and well-being in organizational contexts. In the South African context, health and well-being of managers have gained relevance in organizations and in management sciences. International organizations, in particular, attempt to address the increasing demand for health care and the delivery of health services to their managers. Careful and appropriate health management requires research to evaluate context-specific health concepts and strategies. The purpose and aim of this article is to assess managerial concepts on health and well-being that could be used by the organization to contribute to managerial well-being by implementing health promotion according to managerial needs. At the same time, this article contributes to salutogenetic health research that is very rare with regard to the South African organizational management research. This study is a multi-method research study conducted in a selected international organization in South Africa. However, in this article, selected qualitative findings will only be presented. This organizational study presents selected research findings on health concepts and strategies employed by managers. Findings demonstrate that the managerial concepts of health and strategies mainly refer to not only physical but also to mental and spiritual aspects, with a priority on physical health and well-being. The findings presented are based on qualitative research methods and their research criteria. This assessment serves as a foundation for new approaches to health management within the international work context in South Africa. It also contributes to a paradigm shift from pathogenetic to salutogenetic concepts of health and well-being within the South African organizational work context. The article produces new insights into the qualitative health concepts of South African managers and expatriates and contributes to promoting salutogenesis in organization within South Africa. PMID:22028736

The conception of life in synthetic biology.

PubMed

Deplazes-Zemp, Anna

2012-12-01

The phrase 'synthetic biology' is used to describe a set of different scientific and technological disciplines, which share the objective to design and produce new life forms. This essay addresses the following questions: What conception of life stands behind this ambitious objective? In what relation does this conception of life stand to that of traditional biology and biotechnology? And, could such a conception of life raise ethical concerns? Three different observations that provide useful indications for the conception of life in synthetic biology will be discussed in detail: 1. Synthetic biologists focus on different features of living organisms in order to design new life forms, 2. Synthetic biologists want to contribute to the understanding of life, and 3. Synthetic biologists want to modify life through a rational design, which implies the notions of utilising, minimising/optimising, varying and overcoming life. These observations indicate a tight connection between science and technology, a focus on selected aspects of life, a production-oriented approach to life, and a design-oriented understanding of life. It will be argued that through this conception of life synthetic biologists present life in a different light. This conception of life will be illustrated by the metaphor of a toolbox. According to the notion of life as a toolbox, the different features of living organisms are perceived as various rationally designed instruments that can be used for the production of the living organism itself or secondary products made by the organism. According to certain ethical positions this conception of life might raise ethical concerns related to the status of the organism, the motives of the scientists and the role of technology in our society.

A multiisotope C and N modeling analysis of soil organic matter turnover and transport as a function of soil depth in a California annual grassland soil chronosequence

USGS Publications Warehouse

Baisden, W.T.; Amundson, Ronald; Brenner, D.L.; Cook, A.C.; Kendall, C.; Harden, J.W.

2002-01-01

We examine soil organic matter (SOM) turnover and transport using C and N isotopes in soil profiles sampled circa 1949, 1978, and 1998 (a period spanning pulse thermonuclear 14C enrichment of the atmosphere) along a 3-million-year annual grassland soil chronosequence. Temporal differences in soil ??14C profiles indicate that inputs of recently living organic matter (OM) occur primarily in the upper 20-30 cm but suggest that OM inputs can occur below the primary rooting zone. A three-pool SOM model with downward transport captures most observed variation in ??14C, percentages of C and N, ??13C, and ??15N, supporting the commonly accepted concept of three distinct SOM pools. The model suggests that the importance of the decadal SOM pool in N dynamics is greatest in young and old soils. Altered hydrology and possibly low pH and/or P dynamics in highly developed old soils cause changes in soil C and N turnover and transport of importance for soil biogeochemistry models.

Abstraction of complex concepts with a refined partial-area taxonomy of SNOMED

PubMed Central

Wang, Yue; Halper, Michael; Wei, Duo; Perl, Yehoshua; Geller, James

2012-01-01

An algorithmically-derived abstraction network, called the partial-area taxonomy, for a SNOMED hierarchy has led to the identification of concepts considered complex. The designation “complex” is arrived at automatically on the basis of structural analyses of overlap among the constituent concept groups of the partial-area taxonomy. Such complex concepts, called overlapping concepts, constitute a tangled portion of a hierarchy and can be obstacles to users trying to gain an understanding of the hierarchy’s content. A new methodology for partitioning the entire collection of overlapping concepts into singly-rooted groups, that are more manageable to work with and comprehend, is presented. Different kinds of overlapping concepts with varying degrees of complexity are identified. This leads to an abstract model of the overlapping concepts called the disjoint partial-area taxonomy, which serves as a vehicle for enhanced, high-level display. The methodology is demonstrated with an application to SNOMED’s Specimen hierarchy. Overall, the resulting disjoint partial-area taxonomy offers a refined view of the hierarchy’s structural organization and conceptual content that can aid users, such as maintenance personnel, working with SNOMED. The utility of the disjoint partial-area taxonomy as the basis for a SNOMED auditing regimen is presented in a companion paper. PMID:21878396

Provider Network Development under the Department of Defense Coordinated Care Program: A Methodology for Primary Care Network Development and Its Implementation in the San Antonio Service Area

DTIC Science & Technology

1993-04-01

for using out-of- network benefits . * A gatekeeper physician controls access to the network and is paid on a capitated or discounted fee- for-service...Model ...................... 84 Figure 10. Organization Under Managed Care/HMO Concept ............... 94 APPENDIX 1. Benefit Under CCP 2. Group Model...increases, yet our health indicators have not improved (e.g., infant mortality, adult mortality, morbidity, or life expectancy). The aging population, the

Phase Transitions in a Model for Social Learning via the Internet

NASA Astrophysics Data System (ADS)

Bordogna, Clelia M.; Albano, Ezequiel V.

Based on the concepts of educational psychology, sociology and statistical physics, a mathematical model for a new type of social learning process that takes place when individuals interact via the Internet is proposed and studied. The noise of the interaction (misunderstandings, lack of well organized participative activities, etc.) dramatically restricts the number of individuals that can be efficiently in mutual contact and drives phase transitions between ``ordered states'' such as the achievements of the individuals are satisfactory and ``disordered states'' with negligible achievements.

Effectiveness of Analogy Instructional Strategy on Undergraduate Student's Acquisition of Organic Chemistry Concepts in Mutah University, Jordan

ERIC Educational Resources Information Center

Samara, Nawaf Ahmad Hasan

2016-01-01

This study aimed at investigating the effectiveness of analogy instructional strategy on undergraduate students' acquisition of organic chemistry concepts in Mutah University, Jordan. A quasi-experimental design was used in the study; Participants were 97 students who enrolled in organic chemistry course at the department of chemistry during the…

The Influence of Presentation, Organization, and Example Context on Text Learning

ERIC Educational Resources Information Center

McCrudden, Matthew; Schraw, Gregory; Hartley, Kendall; Kiewra, Kenneth

2004-01-01

This research compared high-load and low-load versions of a text by manipulating text presentation, text organization, and example context on measures of fact and concept learning. The low-load text presentation variable enhanced fact and concept learning and post-reading ease of comprehension ratings. The low-load text organization variable led…

Bringing voice in policy building.

PubMed

Lotrecchiano, Gaetano R; Kane, Mary; Zocchi, Mark S; Gosa, Jessica; Lazar, Danielle; Pines, Jesse M

2017-07-03

Purpose The purpose of this paper is to describe the use of group concept mapping (GCM) as a tool for developing a conceptual model of an episode of acute, unscheduled care from illness or injury to outcomes such as recovery, death and chronic illness. Design/methodology/approach After generating a literature review drafting an initial conceptual model, GCM software (CS Global MAX TM ) is used to organize and identify strengths and directionality between concepts generated through feedback about the model from several stakeholder groups: acute care and non-acute care providers, patients, payers and policymakers. Through online and in-person population-specific focus groups, the GCM approach seeks feedback, assigned relationships and articulated priorities from participants to produce an output map that described overarching concepts and relationships within and across subsamples. Findings A clustered concept map made up of relational data points that produced a taxonomy of feedback was used to update the model for use in soliciting additional feedback from two technical expert panels (TEPs), and finally, a public comment exercise was performed. The results were a stakeholder-informed improved model for an acute care episode, identified factors that influence process and outcomes, and policy recommendations, which were delivered to the Department of Health and Human Services's (DHHS) Assistant Secretary for Preparedness and Response. Practical implications This study provides an example of the value of cross-population multi-stakeholder input to increase voice in shared problem health stakeholder groups. Originality/value This paper provides GCM results and a visual analysis of the relational characteristics both within and across sub-populations involved in the study. It also provides an assessment of observational key factors supporting how different stakeholder voices can be integrated to inform model development and policy recommendations.

Prospective Environmental Risk Assessment for Sediment-Bound Organic Chemicals: A Proposal for Tiered Effect Assessment.

PubMed

Diepens, Noël J; Koelmans, Albert A; Baveco, Hans; van den Brink, Paul J; van den Heuvel-Greve, Martine J; Brock, Theo C M

A broadly accepted framework for prospective environmental risk assessment (ERA) of sediment-bound organic chemicals is currently lacking. Such a framework requires clear protection goals, evidence-based concepts that link exposure to effects and a transparent tiered-effect assessment. In this paper, we provide a tiered prospective sediment ERA procedure for organic chemicals in sediment, with a focus on the applicable European regulations and the underlying data requirements. Using the ecosystem services concept, we derived specific protection goals for ecosystem service providing units: microorganisms, benthic algae, sediment-rooted macrophytes, benthic invertebrates and benthic vertebrates. Triggers for sediment toxicity testing are discussed.We recommend a tiered approach (Tier 0 through Tier 3). Tier-0 is a cost-effective screening based on chronic water-exposure toxicity data for pelagic species and equilibrium partitioning. Tier-1 is based on spiked sediment laboratory toxicity tests with standard benthic test species and standardised test methods. If comparable chronic toxicity data for both standard and additional benthic test species are available, the Species Sensitivity Distribution (SSD) approach is a more viable Tier-2 option than the geometric mean approach. This paper includes criteria for accepting results of sediment-spiked single species toxicity tests in prospective ERA, and for the application of the SSD approach. We propose micro/mesocosm experiments with spiked sediment, to study colonisation success by benthic organisms, as a Tier-3 option. Ecological effect models can be used to supplement the experimental tiers. A strategy for unifying information from various tiers by experimental work and exposure-and effect modelling is provided.

Cinematic Operation of the Cerebral Cortex Interpreted via Critical Transitions in Self-Organized Dynamic Systems

PubMed Central

Kozma, Robert; Freeman, Walter J.

2017-01-01

Measurements of local field potentials over the cortical surface and the scalp of animals and human subjects reveal intermittent bursts of beta and gamma oscillations. During the bursts, narrow-band metastable amplitude modulation (AM) patters emerge for a fraction of a second and ultimately dissolve to the broad-band random background activity. The burst process depends on previously learnt conditioned stimuli (CS), thus different AM patterns may emerge in response to different CS. This observation leads to our cinematic theory of cognition when perception happens in discrete steps manifested in the sequence of AM patterns. Our article summarizes findings in the past decades on experimental evidence of cinematic theory of cognition and relevant mathematical models. We treat cortices as dissipative systems that self-organize themselves near a critical level of activity that is a non-equilibrium metastable state. Criticality is arguably a key aspect of brains in their rapid adaptation, reconfiguration, high storage capacity, and sensitive response to external stimuli. Self-organized criticality (SOC) became an important concept to describe neural systems. We argue that transitions from one AM pattern to the other require the concept of phase transitions, extending beyond the dynamics described by SOC. We employ random graph theory (RGT) and percolation dynamics as fundamental mathematical approaches to model fluctuations in the cortical tissue. Our results indicate that perceptions are formed through a phase transition from a disorganized (high entropy) to a well-organized (low entropy) state, which explains the swiftness of the emergence of the perceptual experience in response to learned stimuli. PMID:28352218

Three layer functional model and energy exchange concept of aging process

PubMed Central

Mihajlovic, William

2006-01-01

Relying on a certain degree of abstraction, we can propose that no particular distinction exists between animate or living matter and inanimate matter. While focusing attention on some specifics, the dividing line between the two can be drawn. The most apparent distinction is in the level of structural and functional organization with the dissimilar streams of ‘energy flow’ between the observed entity and the surrounding environment. In essence, living matter is created from inanimate matter which is organized to contain internal intense energy processes and maintain lower intensity energy exchange processes with the environment. Taking internal and external energy processes into account, we contend in this paper that living matter can be referred to as matter of dissipative structure, with this structure assumed to be a common quality of all living creatures and living matter in general. Interruption of internal energy conversion processes and terminating the controlled energy exchange with the environment leads to degeneration of dissipative structure and reduction of the same to inanimate matter, (gas, liquid and/or solid inanimate substances), and ultimately what can be called ‘death.’ This concept of what we call dissipative nature can be extended from living organisms to social groups of animals, to mankind. An analogy based on the organization of matter provides a basis for a functional model of living entities. The models relies on the parallels among the three central structures of any cell (nucleus, cytoplasm and outer membrane) and the human body (central organs, body fluids along with the connective tissues, and external skin integument). This three-part structural organization may be observed almost universally in nature. It can be observed from the atomic structure to the planetary and intergalactic organizations. This similarity is corroborated by the membrane theory applied to living organisms. According to the energy nature of living matter and the proposed functional model, the decreased integrity of a human body's external envelope membrane is a first cause of the structural degradation and aging of the entire organism. The aging process than progresses externally to internally, as in single cell organisms, suggesting that much of the efforts towards the restoration and maintenance of the mechanisms responsible for structural development should be focused accordingly, on the membrane, i.e., the skin. Numerous reports indicate that all parts of the human body, like: bones, blood with blood vessels, muscles, skin, and so on, have some ability for restoration. Therefore, actual revival of not only aging tissue of the human body's membrane, but the entire human body enclosed within, with all internal organs, might be expected. We assess several aging theories within the context of our model and provide suggestions on how to activate the body's own anti-aging mechanisms and increase longevity. This paper presents some analogies and some distinctions that exist between the living dissipative structure matter and inanimate matter, discusses the aging process and proposes certain aging reversal solutions. PMID:23598683

Unified percolation model for bipolaron-assisted organic magnetoresistance in the unipolar transport regime

NASA Astrophysics Data System (ADS)

Gao, Nan; Li, Ling; Lu, Nianduan; Xie, Changqing; Liu, Ming; Bässler, Heinz

2016-08-01

The fact that in organic semiconductors the Hubbard energy is usually positive appears to be at variance with a bipolaron model to explain magnetoresistance (MR) in those systems. Employing percolation theory, we demonstrate that a moderately positive U is indeed compatible with the bipolaron concept for MR in unipolar current flow, provided that the system is energetically disordered, and the density of states (DOS) distribution is partially filled, so that the Fermi level overlaps with tail states of the DOS. By exploring a broad parameter space, we show that MR becomes maximal around U =0 and even diminishes at large negative values of U because of spin independent bipolaron dissociation. Trapping effects and reduced dimension enhance MR.

Nurses amidst change: the concept of change fatigue offers an alternative perspective on organizational change.

PubMed

McMillan, Kim; Perron, Amélie

2013-02-01

This article aims to clarify the concept of change fatigue and deems further exploration of the concept within the discipline of nursing is relevant and necessary. The concept of change fatigue has evolved from the discipline of management as a means to explore organization change and its associated triumphs and failures. Change fatigue has typically been described as one and the same as change resistance, with very little literature acknowledging that they are in fact distinct concepts. Concept clarification has highlighted the striking differences and few similarities that exist between the concepts of change fatigue and change resistance. Further exploration and subsequent research on the concept of change fatigue is needed within the discipline of nursing. The concept not only presents new and alternative perspectives on the processes of organization change, but provides opportunity for theory development that recognizes the impact organizational change has on nurses' work lives.

Integrating separation and conversion - Conversion of biorefinery process streams to biobased chemicals and fuels

Treesearch

Joseph J. Bozell; Berenger Biannic; Diana Cedeno; Thomas Elder; Omid Hosseinaei; Lukas Delbeck; Jae-Woo Kim; C.J. O' Lenick; Timothy Young

2014-01-01

Abstract The concept of the integrated biorefinery is critical to developing a robust biorefining industry in the USA.Within this model, the biorefinery will produce fuel as a highvolume output addressing domestic energy needs and biobased chemical products (high-value organics) as an output providing necessary economic support for fuel production. This paper will...

Does the Discourse of Employer Linked Charter Schools Signal a Commitment to Work Force Development or Transformational Learning?

ERIC Educational Resources Information Center

Freeman, Eric; Lakes, Richard D.

2005-01-01

The latest model for educational reform emerging in the US vocational-technical delivery system is the employer linked charter school (ELCS). This emerging concept is viewed as a partnership between constituents in the regular school organization and employers who are directly involved in the school's design, governance, and delivery of learning…

Initiating a Reiki or CAM program in a healthcare organization--developing a business plan.

PubMed

Vitale, Anne

2014-01-01

Complementary and alternative medicine (CAM) services, such as Reiki, continue to be offered to consumers in many hospitals and other health care organizations. There is growing interest among nurses, doctors, and other health care providers for the integration of CAM therapies into traditional settings. Health care organizations are responding to this need but may not know how to start CAM programs. Starting a Reiki program in a health care setting must be envisioned in a business model approach. This article introduces nurses and other health care providers to the basic concepts of business plan development and important steps to follow when starting a Reiki or CAM program.

Adding dynamic rules to self-organizing fuzzy systems

NASA Technical Reports Server (NTRS)

Buhusi, Catalin V.

1992-01-01

This paper develops a Dynamic Self-Organizing Fuzzy System (DSOFS) capable of adding, removing, and/or adapting the fuzzy rules and the fuzzy reference sets. The DSOFS background consists of a self-organizing neural structure with neuron relocation features which will develop a map of the input-output behavior. The relocation algorithm extends the topological ordering concept. Fuzzy rules (neurons) are dynamically added or released while the neural structure learns the pattern. The DSOFS advantages are the automatic synthesis and the possibility of parallel implementation. A high adaptation speed and a reduced number of neurons is needed in order to keep errors under some limits. The computer simulation results are presented in a nonlinear systems modelling application.

The "spare parts person"? Conceptions of the human body and their implications for public attitudes towards organ donation and organ sale

PubMed Central

Schweda, Mark; Schicktanz, Silke

2009-01-01

Background The increasing debate on financial incentives for organ donation raises concerns about a "commodification of the human body". Philosophical-ethical stances on this development depend on assumptions concerning the body and how people think about it. In our qualitative empirical study we analyze public attitudes towards organ donation in their specific relation to conceptions of the human body in four European countries (Cyprus, Germany, the Netherlands and Sweden). This approach aims at a more context-sensitive picture of what "commodification of the body" can mean in concrete clinical decisions concerning organ donation. Results We find that moral intuitions concerning organ donation are rooted in various conceptions of the human body and its relation to the self: a) the body as a mechanical object owned by the self, b) the body as a part of a higher order embodying the self, and c) the body as a hierarchy of organs constitutive of the self. Conclusion The language of commodification is much too simple to capture what is at stake in everyday life intuitions about organ donation and organ sale. We discuss how the plurality of underlying body-self conceptions can be taken into account in the ethical debate, pointing out consequences for an anthropologically informed approach and for a liberal perspective. PMID:19226449

Self-organized criticality in complex systems: Applicability to the interoccurrent and recurrent statistical behavior of earthquakes

NASA Astrophysics Data System (ADS)

Abaimov, Sergey G.

The concept of self-organized criticality is associated with scale-invariant, fractal behavior; this concept is also applicable to earthquake systems. It is known that the interoccurrent frequency-size distribution of earthquakes in a region is scale-invariant and obeys the Gutenberg-Richter power-law dependence. Also, the interoccurrent time-interval distribution is known to obey Poissonian statistics excluding aftershocks. However, to estimate the hazard risk for a region it is necessary to know also the recurrent behavior of earthquakes at a given point on a fault. This behavior has been investigated in the literature, however, major questions remain unresolved. The reason is the small number of earthquakes in observed sequences. To overcome this difficulty this research utilizes numerical simulations of a slider-block model and a sand-pile model. Also, experimental observations of creep events on the creeping section of the San Andreas fault are processed and sequences up to 100 events are studied. Then the recurrent behavior of earthquakes at a given point on a fault or at a given fault is investigated. It is shown that both the recurrent frequency-size and the time-interval behaviors of earthquakes obey the Weibull distribution.

Vigor of survival determinism: subtle evolutionary gradualism interspersed with robust phylogenetic leaping.

PubMed

Krsmanovic, Pavle

2017-12-01

Discussions of the survival determinism concept have previously focused on its primary role in the evolution of early unicellular organisms in the light of findings which have been reported on a number of diseases. The rationale for such parallel was in the view according to which multicellular organisms could be regarded as sophisticated colonies of semi-autonomous, single-celled entities, whereby various diseases were described as conditions arising upon the activation of the respective survival mechanisms in a milieu unsuitable for such robust stress response. The cellular mechanisms that were discussed in these contexts have been known to play various roles in other biological processes. The proposed notion could thereby be further extended to discussion on mechanisms for the implementation of the respective survival pathways in the development of metazoa, considering that they would have been propagated in their evolution for so long. This manuscript first presents a concise overview of the model previously discussed, followed by the discussion on the role of respective mechanism(s) in origins and development of metazoa. Finally, a reflection on the concept in relation to the prominent evolutionary models is put forward to illustrate a broader context of what is being discussed.

Towards a scientific concept of free will as a biological trait: spontaneous actions and decision-making in invertebrates

PubMed Central

Brembs, Björn

2011-01-01

Until the advent of modern neuroscience, free will used to be a theological and a metaphysical concept, debated with little reference to brain function. Today, with ever increasing understanding of neurons, circuits and cognition, this concept has become outdated and any metaphysical account of free will is rightfully rejected. The consequence is not, however, that we become mindless automata responding predictably to external stimuli. On the contrary, accumulating evidence also from brains much smaller than ours points towards a general organization of brain function that incorporates flexible decision-making on the basis of complex computations negotiating internal and external processing. The adaptive value of such an organization consists of being unpredictable for competitors, prey or predators, as well as being able to explore the hidden resource deterministic automats would never find. At the same time, this organization allows all animals to respond efficiently with tried-and-tested behaviours to predictable and reliable stimuli. As has been the case so many times in the history of neuroscience, invertebrate model systems are spearheading these research efforts. This comparatively recent evidence indicates that one common ability of most if not all brains is to choose among different behavioural options even in the absence of differences in the environment and perform genuinely novel acts. Therefore, it seems a reasonable effort for any neurobiologist to join and support a rather illustrious list of scholars who are trying to wrestle the term ‘free will’ from its metaphysical ancestry. The goal is to arrive at a scientific concept of free will, starting from these recently discovered processes with a strong emphasis on the neurobiological mechanisms underlying them. PMID:21159679

Towards a scientific concept of free will as a biological trait: spontaneous actions and decision-making in invertebrates.

PubMed

Brembs, Björn

2011-03-22

Until the advent of modern neuroscience, free will used to be a theological and a metaphysical concept, debated with little reference to brain function. Today, with ever increasing understanding of neurons, circuits and cognition, this concept has become outdated and any metaphysical account of free will is rightfully rejected. The consequence is not, however, that we become mindless automata responding predictably to external stimuli. On the contrary, accumulating evidence also from brains much smaller than ours points towards a general organization of brain function that incorporates flexible decision-making on the basis of complex computations negotiating internal and external processing. The adaptive value of such an organization consists of being unpredictable for competitors, prey or predators, as well as being able to explore the hidden resource deterministic automats would never find. At the same time, this organization allows all animals to respond efficiently with tried-and-tested behaviours to predictable and reliable stimuli. As has been the case so many times in the history of neuroscience, invertebrate model systems are spearheading these research efforts. This comparatively recent evidence indicates that one common ability of most if not all brains is to choose among different behavioural options even in the absence of differences in the environment and perform genuinely novel acts. Therefore, it seems a reasonable effort for any neurobiologist to join and support a rather illustrious list of scholars who are trying to wrestle the term 'free will' from its metaphysical ancestry. The goal is to arrive at a scientific concept of free will, starting from these recently discovered processes with a strong emphasis on the neurobiological mechanisms underlying them.

Optimal allocation in annual plants and its implications for drought response

NASA Astrophysics Data System (ADS)

Caldararu, Silvia; Smith, Matthew; Purves, Drew

2015-04-01

The concept of plant optimality refers to the plastic behaviour of plants that results in lifetime and offspring fitness. Optimality concepts have been used in vegetation models for a variety of processes, including stomatal conductance, leaf phenology and biomass allocation. Including optimality in vegetation models has the advantages of creating process based models with a relatively low complexity in terms of parameter numbers but which are capable of reproducing complex plant behaviour. We present a general model of plant growth for annual plants based on the hypothesis that plants allocate biomass to aboveground and belowground vegetative organs in order to maintain an optimal C:N ratio. The model also represents reproductive growth through a second optimality criteria, which states that plants flower when they reach peak nitrogen uptake. We apply this model to wheat and maize crops at 15 locations corresponding to FLUXNET cropland sites. The model parameters are data constrained using a Bayesian fitting algorithm to eddy covariance data, satellite derived vegetation indices, specifically the MODIS fAPAR product and field level crop yield data. We use the model to simulate the plant drought response under the assumption of plant optimality and show that the plants maintain unstressed total biomass levels under drought for a reduction in precipitation of up to 40%. Beyond that level plant response stops being plastic and growth decreases sharply. This behaviour results simply from the optimal allocation criteria as the model includes no explicit drought sensitivity component. Models that use plant optimality concepts are a useful tool for simulation plant response to stress without the addition of artificial thresholds and parameters.

Modeling and visualization of carrier motion in organic films by optical second harmonic generation and Maxwell-displacement current

NASA Astrophysics Data System (ADS)

Iwamoto, Mitsumasa; Manaka, Takaaki; Taguchi, Dai

2015-09-01

The probing and modeling of carrier motions in materials as well as in electronic devices is a fundamental research subject in science and electronics. According to the Maxwell electromagnetic field theory, carriers are a source of electric field. Therefore, by probing the dielectric polarization caused by the electric field arising from moving carriers and dipoles, we can find a way to visualize the carrier motions in materials and in devices. The techniques used here are an electrical Maxwell-displacement current (MDC) measurement and a novel optical method based on the electric field induced optical second harmonic generation (EFISHG) measurement. The MDC measurement probes changes of induced charge on electrodes, while the EFISHG probes nonlinear polarization induced in organic active layers due to the coupling of electron clouds of molecules and electro-magnetic waves of an incident laser beam in the presence of a DC field caused by electrons and holes. Both measurements allow us to probe dynamical carrier motions in solids through the detection of dielectric polarization phenomena originated from dipolar motions and electron transport. In this topical review, on the basis of Maxwell’s electro-magnetism theory of 1873, which stems from Faraday’s idea, the concept for probing electron and hole transport in solids by using the EFISHG is discussed in comparison with the conventional time of flight (TOF) measurement. We then visualize carrier transit in organic devices, i.e. organic field effect transistors, organic light emitting diodes, organic solar cells, and others. We also show that visualizing an EFISHG microscopic image is a novel way for characterizing anisotropic carrier transport in organic thin films. We also discuss the concept of the detection of rotational dipolar motions in monolayers by means of the MDC measurement, which is capable of probing the change of dielectric spontaneous polarization formed by dipoles in organic monolayers. Finally we conclude that the ideas and experiments on EFISHG and MDC lead to a novel way of analyzing dynamical motions of electrons, holes, and dipoles in solids, and thus are available in organic electronic device application.

A Dynamical System Approach Explaining the Process of Development by Introducing Different Time-scales.

PubMed

Hashemi Kamangar, Somayeh Sadat; Moradimanesh, Zahra; Mokhtari, Setareh; Bakouie, Fatemeh

2018-06-11

A developmental process can be described as changes through time within a complex dynamic system. The self-organized changes and emergent behaviour during development can be described and modeled as a dynamical system. We propose a dynamical system approach to answer the main question in human cognitive development i.e. the changes during development happens continuously or in discontinuous stages. Within this approach there is a concept; the size of time scales, which can be used to address the aforementioned question. We introduce a framework, by considering the concept of time-scale, in which "fast" and "slow" is defined by the size of time-scales. According to our suggested model, the overall pattern of development can be seen as one continuous function, with different time-scales in different time intervals.

A standard protocol for describing individual-based and agent-based models

USGS Publications Warehouse

Grimm, Volker; Berger, Uta; Bastiansen, Finn; Eliassen, Sigrunn; Ginot, Vincent; Giske, Jarl; Goss-Custard, John; Grand, Tamara; Heinz, Simone K.; Huse, Geir; Huth, Andreas; Jepsen, Jane U.; Jorgensen, Christian; Mooij, Wolf M.; Muller, Birgit; Pe'er, Guy; Piou, Cyril; Railsback, Steven F.; Robbins, Andrew M.; Robbins, Martha M.; Rossmanith, Eva; Ruger, Nadja; Strand, Espen; Souissi, Sami; Stillman, Richard A.; Vabo, Rune; Visser, Ute; DeAngelis, Donald L.

2006-01-01

Simulation models that describe autonomous individual organisms (individual based models, IBM) or agents (agent-based models, ABM) have become a widely used tool, not only in ecology, but also in many other disciplines dealing with complex systems made up of autonomous entities. However, there is no standard protocol for describing such simulation models, which can make them difficult to understand and to duplicate. This paper presents a proposed standard protocol, ODD, for describing IBMs and ABMs, developed and tested by 28 modellers who cover a wide range of fields within ecology. This protocol consists of three blocks (Overview, Design concepts, and Details), which are subdivided into seven elements: Purpose, State variables and scales, Process overview and scheduling, Design concepts, Initialization, Input, and Submodels. We explain which aspects of a model should be described in each element, and we present an example to illustrate the protocol in use. In addition, 19 examples are available in an Online Appendix. We consider ODD as a first step for establishing a more detailed common format of the description of IBMs and ABMs. Once initiated, the protocol will hopefully evolve as it becomes used by a sufficiently large proportion of modellers.

EUD-based biological optimization for carbon ion therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brüningk, Sarah C., E-mail: sarah.brueningk@icr.ac.uk; Kamp, Florian; Wilkens, Jan J.

2015-11-15

Purpose: Treatment planning for carbon ion therapy requires an accurate modeling of the biological response of each tissue to estimate the clinical outcome of a treatment. The relative biological effectiveness (RBE) accounts for this biological response on a cellular level but does not refer to the actual impact on the organ as a whole. For photon therapy, the concept of equivalent uniform dose (EUD) represents a simple model to take the organ response into account, yet so far no formulation of EUD has been reported that is suitable to carbon ion therapy. The authors introduce the concept of an equivalentmore » uniform effect (EUE) that is directly applicable to both ion and photon therapies and exemplarily implemented it as a basis for biological treatment plan optimization for carbon ion therapy. Methods: In addition to a classical EUD concept, which calculates a generalized mean over the RBE-weighted dose distribution, the authors propose the EUE to simplify the optimization process of carbon ion therapy plans. The EUE is defined as the biologically equivalent uniform effect that yields the same probability of injury as the inhomogeneous effect distribution in an organ. Its mathematical formulation is based on the generalized mean effect using an effect-volume parameter to account for different organ architectures and is thus independent of a reference radiation. For both EUD concepts, quadratic and logistic objective functions are implemented into a research treatment planning system. A flexible implementation allows choosing for each structure between biological effect constraints per voxel and EUD constraints per structure. Exemplary treatment plans are calculated for a head-and-neck patient for multiple combinations of objective functions and optimization parameters. Results: Treatment plans optimized using an EUE-based objective function were comparable to those optimized with an RBE-weighted EUD-based approach. In agreement with previous results from photon therapy, the optimization by biological objective functions resulted in slightly superior treatment plans in terms of final EUD for the organs at risk (OARs) compared to voxel-based optimization approaches. This observation was made independent of the underlying objective function metric. An absolute gain in OAR sparing was observed for quadratic objective functions, whereas intersecting DVHs were found for logistic approaches. Even for considerable under- or overestimations of the used effect- or dose–volume parameters during the optimization, treatment plans were obtained that were of similar quality as the results of a voxel-based optimization. Conclusions: EUD-based optimization with either of the presented concepts can successfully be applied to treatment plan optimization. This makes EUE-based optimization for carbon ion therapy a useful tool to optimize more specifically in the sense of biological outcome while voxel-to-voxel variations of the biological effectiveness are still properly accounted for. This may be advantageous in terms of computational cost during treatment plan optimization but also enables a straight forward comparison of different fractionation schemes or treatment modalities.« less

Molecular Phylogenetics: Concepts for a Newcomer.

PubMed

Ajawatanawong, Pravech

Molecular phylogenetics is the study of evolutionary relationships among organisms using molecular sequence data. The aim of this review is to introduce the important terminology and general concepts of tree reconstruction to biologists who lack a strong background in the field of molecular evolution. Some modern phylogenetic programs are easy to use because of their user-friendly interfaces, but understanding the phylogenetic algorithms and substitution models, which are based on advanced statistics, is still important for the analysis and interpretation without a guide. Briefly, there are five general steps in carrying out a phylogenetic analysis: (1) sequence data preparation, (2) sequence alignment, (3) choosing a phylogenetic reconstruction method, (4) identification of the best tree, and (5) evaluating the tree. Concepts in this review enable biologists to grasp the basic ideas behind phylogenetic analysis and also help provide a sound basis for discussions with expert phylogeneticists.

Unifying Screening Processes Within the PROSPR Consortium: A Conceptual Model for Breast, Cervical, and Colorectal Cancer Screening

PubMed Central

Kim, Jane J.; Schapira, Marilyn M.; Tosteson, Anna N. A.; Zauber, Ann G.; Geiger, Ann M.; Kamineni, Aruna; Weaver, Donald L.; Tiro, Jasmin A.

2015-01-01

General frameworks of the cancer screening process are available, but none directly compare the process in detail across different organ sites. This limits the ability of medical and public health professionals to develop and evaluate coordinated screening programs that apply resources and population management strategies available for one cancer site to other sites. We present a trans-organ conceptual model that incorporates a single screening episode for breast, cervical, and colorectal cancers into a unified framework based on clinical guidelines and protocols; the model concepts could be expanded to other organ sites. The model covers four types of care in the screening process: risk assessment, detection, diagnosis, and treatment. Interfaces between different provider teams (eg, primary care and specialty care), including communication and transfer of responsibility, may occur when transitioning between types of care. Our model highlights across each organ site similarities and differences in steps, interfaces, and transitions in the screening process and documents the conclusion of a screening episode. This model was developed within the National Cancer Institute–funded consortium Population-based Research Optimizing Screening through Personalized Regimens (PROSPR). PROSPR aims to optimize the screening process for breast, cervical, and colorectal cancer and includes seven research centers and a statistical coordinating center. Given current health care reform initiatives in the United States, this conceptual model can facilitate the development of comprehensive quality metrics for cancer screening and promote trans-organ comparative cancer screening research. PROSPR findings will support the design of interventions that improve screening outcomes across multiple cancer sites. PMID:25957378

Concept of an Active Amplification Mechanism in the Infrared Organ of Pyrophilous Melanophila Beetles

PubMed Central

Schneider, Erik S.; Schmitz, Anke; Schmitz, Helmut

2015-01-01

Jewel beetles of the genus Melanophila possess a pair of metathoracic infrared (IR) organs. These organs are used for forest fire detection because Melanophila larvae can only develop in fire killed trees. Several reports in the literature and a modeling of a historic oil tank fire suggest that beetles may be able to detect large fires by means of their IR organs from distances of more than 100 km. In contrast, the highest sensitivity of the IR organs, so far determined by behavioral and physiological experiments, allows a detection of large fires from distances up to 12 km only. Sensitivity thresholds, however, have always been determined in non-flying beetles. Therefore, the complete micromechanical environment of the IR organs in flying beetles has not been taken into consideration. Because the so-called photomechanic sensilla housed in the IR organs respond bimodally to mechanical as well as to IR stimuli, it is proposed that flying beetles make use of muscular energy coupled out of the flight motor to considerably increase the sensitivity of their IR sensilla during intermittent search flight sequences. In a search flight the beetle performs signal scanning with wing beat frequency while the inputs of the IR organs on both body sides are compared. By this procedure the detection of weak IR signals could be possible even if the signals are hidden in the thermal noise. If this proposed mechanism really exists in Melanophila beetles, their IR organs could even compete with cooled IR quantum detectors. The theoretical concept of an active amplification mechanism in a photon receptor innervated by highly sensitive mechanoreceptors is presented in this article. PMID:26733883

Concept of an Active Amplification Mechanism in the Infrared Organ of Pyrophilous Melanophila Beetles.

PubMed

Schneider, Erik S; Schmitz, Anke; Schmitz, Helmut

2015-01-01

Jewel beetles of the genus Melanophila possess a pair of metathoracic infrared (IR) organs. These organs are used for forest fire detection because Melanophila larvae can only develop in fire killed trees. Several reports in the literature and a modeling of a historic oil tank fire suggest that beetles may be able to detect large fires by means of their IR organs from distances of more than 100 km. In contrast, the highest sensitivity of the IR organs, so far determined by behavioral and physiological experiments, allows a detection of large fires from distances up to 12 km only. Sensitivity thresholds, however, have always been determined in non-flying beetles. Therefore, the complete micromechanical environment of the IR organs in flying beetles has not been taken into consideration. Because the so-called photomechanic sensilla housed in the IR organs respond bimodally to mechanical as well as to IR stimuli, it is proposed that flying beetles make use of muscular energy coupled out of the flight motor to considerably increase the sensitivity of their IR sensilla during intermittent search flight sequences. In a search flight the beetle performs signal scanning with wing beat frequency while the inputs of the IR organs on both body sides are compared. By this procedure the detection of weak IR signals could be possible even if the signals are hidden in the thermal noise. If this proposed mechanism really exists in Melanophila beetles, their IR organs could even compete with cooled IR quantum detectors. The theoretical concept of an active amplification mechanism in a photon receptor innervated by highly sensitive mechanoreceptors is presented in this article.

The transfer and implementation of an Aboriginal Australian wellbeing program: a grounded theory study

PubMed Central

2013-01-01

Background The concepts and standard practices of implementation, largely originating in developed countries, cannot necessarily be simply transferred into diverse cultural contexts. There has been relative inattention in the implementation science literature paid to the implementation of interventions targeting minority Indigenous populations within developed countries. This suggests that the implementation literature may be bypassing population groups within developed countries who suffer some of the greatest disadvantage. Within the context of Aboriginal Australian health improvement, this study considers the impact of political and cultural issues by examining the transfer and implementation of the Family Wellbeing program across 56 places over a 20-year period. Methods A theoretical model of program transfer was developed using constructivist-grounded theory methods. Data were generated by conducting in-depth interviews with 18 Aboriginal and non-Aboriginal research respondents who had been active in transferring the program. Data were categorised into higher order abstract concepts and the core impetus for and process of program transfer were identified. Results Organizations transferred the program by using it as a vehicle for supporting inside-out empowerment. The impetus to support inside-out empowerment referred to support for Aboriginal people's participation, responsibility for and control of their own affairs, and the associated ripple effects to family members, organizations, communities, and ultimately reconciliation with Australian society at large. Program transfer occurred through a multi-levelled process of embracing relatedness which included relatedness with self, others, and structural conditions; all three were necessary at both individual and organizational levels. Conclusions Similar to international implementation models, the model of supporting inside-out empowerment by embracing relatedness involved individuals, organizations, and interpersonal and inter-organizational networks. However, the model suggests that for minority Indigenous populations within developed countries, implementation approaches may require greater attention to the empowering nature of the intervention and its implementation, and multiple levels of relatedness by individuals and organizations with self, others, and the structural conditions. Key elements of the theoretical model provide a useful blueprint to inform the transfer of other empowerment programs to minority Indigenous and other disadvantaged populations on a case-by-case basis. PMID:24171867

The transfer and implementation of an Aboriginal Australian wellbeing program: a grounded theory study.

PubMed

McCalman, Janya R

2013-10-31

The concepts and standard practices of implementation, largely originating in developed countries, cannot necessarily be simply transferred into diverse cultural contexts. There has been relative inattention in the implementation science literature paid to the implementation of interventions targeting minority Indigenous populations within developed countries. This suggests that the implementation literature may be bypassing population groups within developed countries who suffer some of the greatest disadvantage. Within the context of Aboriginal Australian health improvement, this study considers the impact of political and cultural issues by examining the transfer and implementation of the Family Wellbeing program across 56 places over a 20-year period. A theoretical model of program transfer was developed using constructivist-grounded theory methods. Data were generated by conducting in-depth interviews with 18 Aboriginal and non-Aboriginal research respondents who had been active in transferring the program. Data were categorised into higher order abstract concepts and the core impetus for and process of program transfer were identified. Organizations transferred the program by using it as a vehicle for supporting inside-out empowerment. The impetus to support inside-out empowerment referred to support for Aboriginal people's participation, responsibility for and control of their own affairs, and the associated ripple effects to family members, organizations, communities, and ultimately reconciliation with Australian society at large. Program transfer occurred through a multi-levelled process of embracing relatedness which included relatedness with self, others, and structural conditions; all three were necessary at both individual and organizational levels. Similar to international implementation models, the model of supporting inside-out empowerment by embracing relatedness involved individuals, organizations, and interpersonal and inter-organizational networks. However, the model suggests that for minority Indigenous populations within developed countries, implementation approaches may require greater attention to the empowering nature of the intervention and its implementation, and multiple levels of relatedness by individuals and organizations with self, others, and the structural conditions. Key elements of the theoretical model provide a useful blueprint to inform the transfer of other empowerment programs to minority Indigenous and other disadvantaged populations on a case-by-case basis.

Analysis of the Effect of Sequencing Lecture and Laboratory Instruction on Student Learning and Motivation Towards Learning Chemistry in an Organic Chemistry Lecture Course

ERIC Educational Resources Information Center

Pakhira, Deblina

2012-01-01

Exposure to organic chemistry concepts in the laboratory can positively affect student performance, learning new chemistry concepts and building motivation towards learning chemistry in the lecture. In this study, quantitative methods were employed to assess differences in student performance, learning, and motivation in an organic chemistry…

Incorporation of Medicinal Chemistry into the Organic Chemistry Curriculum

ERIC Educational Resources Information Center

Forbes, David C.

2004-01-01

Application of concepts presented in organic chemistry lecture using a virtual project involving the sythesis of medicinally important compounds is emphasized. The importance of reinforcing the concepts from lecture in lab, thus providing a powerful instructional means is discussed.

Modeling mammary organogenesis from biological first principles: Cells and their physical constraints.

PubMed

Montévil, Maël; Speroni, Lucia; Sonnenschein, Carlos; Soto, Ana M

2016-10-01

In multicellular organisms, relations among parts and between parts and the whole are contextual and interdependent. These organisms and their cells are ontogenetically linked: an organism starts as a cell that divides producing non-identical cells, which organize in tri-dimensional patterns. These association patterns and cells types change as tissues and organs are formed. This contextuality and circularity makes it difficult to establish detailed cause and effect relationships. Here we propose an approach to overcome these intrinsic difficulties by combining the use of two models; 1) an experimental one that employs 3D culture technology to obtain the structures of the mammary gland, namely, ducts and acini, and 2) a mathematical model based on biological principles. The typical approach for mathematical modeling in biology is to apply mathematical tools and concepts developed originally in physics or computer sciences. Instead, we propose to construct a mathematical model based on proper biological principles. Specifically, we use principles identified as fundamental for the elaboration of a theory of organisms, namely i) the default state of cell proliferation with variation and motility and ii) the principle of organization by closure of constraints. This model has a biological component, the cells, and a physical component, a matrix which contains collagen fibers. Cells display agency and move and proliferate unless constrained; they exert mechanical forces that i) act on collagen fibers and ii) on other cells. As fibers organize, they constrain the cells on their ability to move and to proliferate. The model exhibits a circularity that can be interpreted in terms of closure of constraints. Implementing the mathematical model shows that constraints to the default state are sufficient to explain ductal and acinar formation, and points to a target of future research, namely, to inhibitors of cell proliferation and motility generated by the epithelial cells. The success of this model suggests a step-wise approach whereby additional constraints imposed by the tissue and the organism could be examined in silico and rigorously tested by in vitro and in vivo experiments, in accordance with the organicist perspective we embrace. Copyright © 2016. Published by Elsevier Ltd.

Modeling mammary organogenesis from biological first principles: Cells and their physical constraints

PubMed Central

Montévil, Maël; Speroni, Lucia; Sonnenschein, Carlos; Soto, Ana M.

2017-01-01

In multicellular organisms, relations among parts and between parts and the whole are contextual and interdependent. These organisms and their cells are ontogenetically linked: an organism starts as a cell that divides producing non-identical cells, which organize in tri-dimensional patterns. These association patterns and cells types change as tissues and organs are formed. This contextuality and circularity makes it difficult to establish detailed cause and effect relationships. Here we propose an approach to overcome these intrinsic difficulties by combining the use of two models; 1) an experimental one that employs 3D culture technology to obtain the structures of the mammary gland, namely, ducts and acini, and 2) a mathematical model based on biological principles. The typical approach for mathematical modeling in biology is to apply mathematical tools and concepts developed originally in physics or computer sciences. Instead, we propose to construct a mathematical model based on proper biological principles. Specifically, we use principles identified as fundamental for the elaboration of a theory of organisms, namely i) the default state of cell proliferation with variation and motility and ii) the principle of organization by closure of constraints. This model has a biological component, the cells, and a physical component, a matrix which contains collagen fibers. Cells display agency and move and proliferate unless constrained; they exert mechanical forces that i) act on collagen fibers and ii) on other cells. As fibers organize, they constrain the cells on their ability to move and to proliferate. The model exhibits a circularity that can be interpreted in terms of closure of constraints. Implementing the mathematical model shows that constraints to the default state are sufficient to explain ductal and acinar formation, and points to a target of future research, namely, to inhibitors of cell proliferation and motility generated by the epithelial cells. The success of this model suggests a step-wise approach whereby additional constraints imposed by the tissue and the organism could be examined in silico and rigorously tested by in vitro and in vivo experiments, in accordance with the organicist perspective we embrace. PMID:27544910

``Physical Concepts in Cell Biology,'' an upper level interdisciplinary course in cell biophysics/mathematical biology

NASA Astrophysics Data System (ADS)

Vavylonis, Dimitrios

2009-03-01

I will describe my experience in developing an interdisciplinary biophysics course addressed to students at the upper undergraduate and graduate level, in collaboration with colleagues in physics and biology. The students had a background in physics, biology and engineering, and for many the course was their first exposure to interdisciplinary topics. The course did not depend on a formal knowledge of equilibrium statistical mechanics. Instead, the approach was based on dynamics. I used diffusion as a universal ``long time'' law to illustrate scaling concepts. The importance of statistics and proper counting of states/paths was introduced by calculating the maximum accuracy with which bacteria can measure the concentration of diffuse chemicals. The use of quantitative concepts and methods was introduced through specific biological examples, focusing on model organisms and extremes at the cell level. Examples included microtubule dynamic instability, the search and capture model, molecular motor cooperativity in muscle cells, mitotic spindle oscillations in C. elegans, polymerization forces and propulsion of pathogenic bacteria, Brownian ratchets, bacterial cell division and MinD oscillations.

Concepts for a NASA Applied Spaceflight Environments Office

NASA Technical Reports Server (NTRS)

Edwards, David L.; Burns, Howard D.; Xapsos, Michael; Spann, Jim; Suggs, Robert

2010-01-01

The National Aeronautics and Space Administration (NASA) is launching a bold and ambitious new space initiative. A significant part of this new initiative includes exploration of new worlds, the development of more innovative technologies, and expansion our presence in the solar system. A common theme to this initiative is the exploration of space beyond Low Earth Orbit (LEO). As currently organized, NASA does not have an Agency-level office that provides coordination of space environment research and development. This has contributed to the formation of a gap between spaceflight environments knowledge and the application of this knowledge for multi-program use. This paper outlines a concept to establish a NASA-level Applied Spaceflight Environments (ASE) office that will provide coordination and funding for sustained multi-program support in three technical areas that have demonstrated these needs through customer requests. These technical areas are natural environments characterization and modeling, materials and systems analysis and test, and operational space environments modeling and prediction. This paper will establish the need for the ASE, discuss a concept for organizational structure and outline the scope in the three technical areas

Human-pet interaction and loneliness: a test of concepts from Roy's adaptation model.

PubMed

Calvert, M M

1989-01-01

This research used two key concepts from Roy's adaptation model of nursing to examine the relationship between human-pet interaction and loneliness in nursing home residents. These concepts included (a) environmental stimuli as factors influencing adaptation and (b) interdependence as a mode of response to the environment. The hypothesis of this study asserted that the residents of a nursing home who had greater levels of interaction with a pet program would experience less loneliness than those who had lower levels of interaction with a pet. The study used an ex post facto nonexperimental design with 65 subjects. The simplified version of the revised UCLA loneliness scale was used to measure loneliness. Reported level of human-pet interaction was measured according to a four-point scale (1 = no interaction, 4 = quite a lot of interaction). The hypothesis was supported at the p less than 0.03 level of significance. Implications for practice through organizing pet programs in situations where loneliness exists are discussed. Recommendations for future research include replicating the study using a larger sample and developing a comprehensive human-pet interaction tool.

Artificial consciousness, artificial emotions, and autonomous robots.

PubMed

Cardon, Alain

2006-12-01

Nowadays for robots, the notion of behavior is reduced to a simple factual concept at the level of the movements. On another hand, consciousness is a very cultural concept, founding the main property of human beings, according to themselves. We propose to develop a computable transposition of the consciousness concepts into artificial brains, able to express emotions and consciousness facts. The production of such artificial brains allows the intentional and really adaptive behavior for the autonomous robots. Such a system managing the robot's behavior will be made of two parts: the first one computes and generates, in a constructivist manner, a representation for the robot moving in its environment, and using symbols and concepts. The other part achieves the representation of the previous one using morphologies in a dynamic geometrical way. The robot's body will be seen for itself as the morphologic apprehension of its material substrata. The model goes strictly by the notion of massive multi-agent's organizations with a morphologic control.

MO-E-17A-06: Organ Dose in Abdomen-Pelvis CT: Does TG 111 Equilibrium Dose Concept Better Accounts for KVp Dependence Than Conventional CTDI?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, X; Morgan, A; Davros, W

Purpose: In CT imaging, a desirable quality assurance (QA) dose quantity should account for the dose variability across scan parameters and scanner models. Recently, AAPM TG 111 proposed to use equilibrium dose-pitch product, in place of CT dose index (CTDI100), for scan modes involving table translation. The purpose of this work is to investigate whether this new concept better accounts for the kVp dependence of organ dose than the conventional CTDI concept. Methods: The adult reference female extended cardiac-torso (XCAT) phantom was used for this study. A Monte Carlo program developed and validated for a 128-slice CT system (Definition Flash,more » Siemens Healthcare) was used to simulate organ dose for abdomenpelvis scans at five tube voltages (70, 80, 100, 120, 140 kVp) with a pitch of 0.8 and a detector configuration of 2x64x0.6 mm. The same Monte Carlo program was used to simulate CTDI100 and equilibrium dose-pitch product. For both metrics, the central and peripheral values were used together with helical pitch to calculate a volume-weighted average, i.e., CTDIvol and (Deq)vol, respectively. Results: While other scan parameters were kept constant, organ dose depended strongly on kVp; the coefficient of variation (COV) across the five kVp values ranged between 70–75% for liver, spleen, stomach, pancreas, kidneys, colon, small intestine, bladder, and ovaries, all of which were inside the primary radiation beam. One-way analysis of variance (ANOVA) for the effect of kVp was highly significant (p=3e−30). When organ dose was normalized by CTDIvol, the COV across the five kVp values reduced to 7–16%. The effect of kVp was still highly significant (p=4e−4). When organ dose was normalized by (Deq)vol, the COV further reduced to 4−12%. The effect of kVp was borderline significant (p=0.04). Conclusion: In abdomen-pelvis CT, TG 111 equilibrium dose concept better accounts for kVp dependence than the conventional CTDI. This work is supported by a faculty startup fund from the Cleveland State University.« less

A Catalogue of Concepts in the Pedagogical Domain of Teacher Education.

ERIC Educational Resources Information Center

Multi-State Consortium on Performance-Based Teacher Education, Albany, NY.

This catalog of concepts in the pedagogical domain of teacher education organizes the critical concepts and provides definitions, indicators, and illustrations of the concepts. Chapter 1 presents a rationale for the selection of concepts in teacher education and discusses pedagogical domain, interactive teaching, the format of concepts in this…

On Modeling Research Work for Describing and Filtering Scientific Information

NASA Astrophysics Data System (ADS)

Sicilia, Miguel-Ángel

Existing models for Research Information Systems (RIS) properly address the description of people and organizations, projects, facilities and their outcomes, e.g. papers, reports or patents. While this is adequate for the recording and accountability of research investments, helping researchers in finding relevant people, organizations or results requires considering both the content of research work and also its context. The content is not only related to the domain area, but it requires modeling methodological issues as variables, instruments or scientific methods that can then be used as search criteria. The context of research work is determined by the ongoing projects or scientific interests of an individual or a group, and can be expressed using the same methodological concepts. However, modeling methodological issues is notably complex and dependent on the scientific discipline and research area. This paper sketches the main requirements for those models, providing some motivating examples that could serve as a point of departure for future attempts in developing an upper ontology for research methods and tools.

Revealing Long-Range Interconnected Hubs in Human Chromatin Interaction Data Using Graph Theory

NASA Astrophysics Data System (ADS)

Boulos, R. E.; Arneodo, A.; Jensen, P.; Audit, B.

2013-09-01

We use graph theory to analyze chromatin interaction (Hi-C) data in the human genome. We show that a key functional feature of the genome—“master” replication origins—corresponds to DNA loci of maximal network centrality. These loci form a set of interconnected hubs both within chromosomes and between different chromosomes. Our results open the way to a fruitful use of graph theory concepts to decipher DNA structural organization in relation to genome functions such as replication and transcription. This quantitative information should prove useful to discriminate between possible polymer models of nuclear organization.

High level organizing principles for display of systems fault information for commercial flight crews

NASA Technical Reports Server (NTRS)

Rogers, William H.; Schutte, Paul C.

1993-01-01

Advanced fault management aiding concepts for commercial pilots are being developed in a research program at NASA Langley Research Center. One aim of this program is to re-evaluate current design principles for display of fault information to the flight crew: (1) from a cognitive engineering perspective and (2) in light of the availability of new types of information generated by advanced fault management aids. The study described in this paper specifically addresses principles for organizing fault information for display to pilots based on their mental models of fault management.

Autonomous Dynamically Self-Organizing and Self-Healing Distributed Hardware Architecture - the eDNA Concept

NASA Technical Reports Server (NTRS)

Boesen, Michael Reibel; Madsen, Jan; Keymeulen, Didier

2011-01-01

This paper presents the current state of the autonomous dynamically self-organizing and self-healing electronic DNA (eDNA) hardware architecture (patent pending). In its current prototype state, the eDNA architecture is capable of responding to multiple injected faults by autonomously reconfiguring itself to accommodate the fault and keep the application running. This paper will also disclose advanced features currently available in the simulation model only. These features are future work and will soon be implemented in hardware. Finally we will describe step-by-step how an application is implemented on the eDNA architecture.

The affirmation of self: a new perspective on the immune system.

PubMed

Stewart, John; Coutinho, Antonio

2004-01-01

The fundamental concepts of autopoiesis, which emphasize the circular organization underlying both living organisms and cognition, have been criticized on the grounds that since they are conceived as a tight logical chain of definitions and implications, it is often not clear whether they are indeed a scientific theory or rather just a potential scientific vocabulary of doubtful utility to working scientists. This article presents the deployment of the concepts of autopoiesis in the field of immunology, a discipline where working biologists themselves spontaneously have long had recourse to "cognitive" metaphors: "recognition"; a "repertoire" of recognized molecular shapes; "learning" and "memory"; and, most striking of all, a "self versus non-self" distinction. It is shown that in immunology, the concepts of autopoiesis can be employed to generate clear novel hypotheses, models demonstrating these ideas, testable predictions, and novel therapeutic procedures. Epistemologically, it is shown that the self-non-self distinction, while quite real, is misleadingly named. When a real mechanism for generating this distinction is identified, it appears that the actual operational distinction is between (a) a sufficiently numerous set of initial antigens, present from the start of ontogeny, in conditions that allow for their participation in the construction of the system's organization and operation, and (b) single antigens that are first presented to the system after two successive phases of maturation. To call this a self-non-self distinction obscures the issue by presupposing what it ought to be the job of scientific investigation to explain.

Modelling of the petroleum formation in the Mahakam sediments (Indonesia): Organic geochemical controls of the results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brosse, E.; Burris, J.; Ouidin, J.L.

1990-06-01

Since the Miocene, the delta of the Mahakam River has accumulated thousands of meters of sediments in the eastern part of the Kutei Basin (Kalimantan, Indonesia). Source-rock candidates are the coals of the deltaic plain and several types of shales, mainly the delta front/prodelta area. Organic matter basically derives from higher plants, but each source facies presents important intrinsic variations of petroleum potential. These variations are overprinted by subsequent maturation trends. Geochemical and petrographical data are integrated on the general framework provided by a new synthetic interpretation of the sedimentary sequences, relying upon the concepts of seismic stratigraphy. From coremore » samples at a given level of maturation, the variations of several organic parameters are discussed in relation to the depositional paleoenvironment and to the possible precursors. 1D and 2D numerical routines are used to reconstruct the maturation history of source rocks. These tools are based upon a kinetic modeling of kerogen cracking. Model outputs are compared with observed maturation trends. The understanding of the initial organic facies distribution provides precise constraints in the selection of a homogenous samples set for this comparison purpose.« less

25 Years of Self-Organized Criticality: Solar and Astrophysics

NASA Astrophysics Data System (ADS)

Aschwanden, Markus J.; Crosby, Norma B.; Dimitropoulou, Michaila; Georgoulis, Manolis K.; Hergarten, Stefan; McAteer, James; Milovanov, Alexander V.; Mineshige, Shin; Morales, Laura; Nishizuka, Naoto; Pruessner, Gunnar; Sanchez, Raul; Sharma, A. Surja; Strugarek, Antoine; Uritsky, Vadim

2016-01-01

Shortly after the seminal paper "Self-Organized Criticality: An explanation of 1/ f noise" by Bak et al. (1987), the idea has been applied to solar physics, in "Avalanches and the Distribution of Solar Flares" by Lu and Hamilton (1991). In the following years, an inspiring cross-fertilization from complexity theory to solar and astrophysics took place, where the SOC concept was initially applied to solar flares, stellar flares, and magnetospheric substorms, and later extended to the radiation belt, the heliosphere, lunar craters, the asteroid belt, the Saturn ring, pulsar glitches, soft X-ray repeaters, blazars, black-hole objects, cosmic rays, and boson clouds. The application of SOC concepts has been performed by numerical cellular automaton simulations, by analytical calculations of statistical (powerlaw-like) distributions based on physical scaling laws, and by observational tests of theoretically predicted size distributions and waiting time distributions. Attempts have been undertaken to import physical models into the numerical SOC toy models, such as the discretization of magneto-hydrodynamics (MHD) processes. The novel applications stimulated also vigorous debates about the discrimination between SOC models, SOC-like, and non-SOC processes, such as phase transitions, turbulence, random-walk diffusion, percolation, branching processes, network theory, chaos theory, fractality, multi-scale, and other complexity phenomena. We review SOC studies from the last 25 years and highlight new trends, open questions, and future challenges, as discussed during two recent ISSI workshops on this theme.

Using Castration Surgery in Male Rats to Demonstrate the Physiological Effects of Testosterone on Seminal Vesicle Anatomy in an Undergraduate Laboratory Setting

ERIC Educational Resources Information Center

Belanger, Rachelle M.; Conant, Stephanie B.; Grabowski, Gregory M.

2013-01-01

Rats can be used as a model organism to teach physiological concepts in a laboratory setting. This article describes a two-part laboratory that introduces students to hypothesis testing, experimental design, the appropriate use of controls and surgical techniques. Students perform both a castration and sham-control surgery on male rats and test…

A Study of the Development in Fourth, Fifth and Sixth Grade Children of an Understanding of a Particulate Model of Matter.

ERIC Educational Resources Information Center

Ward, Roger Woodmansee

The study was designed to determine if chronological age is the main factor in a child's ability to develop a particulate concept of matter. Four demonstrations were organized which consisted of a graded series of particle mixing, gas diffusion, dissolving and smoke investigations. The individualized interviews with children were tape recorded. On…

Developing a Research Method for Testing New Curriculum Ideas: Report No. 1 on Using Marketing Research in a Lifelong Learning Organization.

ERIC Educational Resources Information Center

Haskins, Jack B.

A survey method was developed and used to determine interest in new course topics at the Learning Institute for Elders (LIFE) at the University of Central Florida. In the absence of a known validated method for course concept testing, this approach was modeled after the "message pretesting," or formative, research used and validated in…

Overview of Graphical User Interface for ARRBOD (Acute Radiation Risk and BRYNTRN Organ Dose Projection)

NASA Technical Reports Server (NTRS)

Kim, Myung-Hee Y.; Hu, Shaowen; Nounu, Hatem N.; Cucinotta, Francis A.

2010-01-01

Solar particle events (SPEs) pose the risk of acute radiation sickness (ARS) to astronauts, because organ doses from large SPEs may reach critical levels during extra vehicular activities (EVAs) or lightly shielded spacecraft. NASA has developed an organ dose projection model of Baryon transport code (BRYNTRN) with an output data processing module of SUMDOSE, and a probabilistic model of acute radiation risk (ARR). BRYNTRN code operation requires extensive input preparation, and the risk projection models of organ doses and ARR take the output from BRYNTRN as an input to their calculations. With a graphical user interface (GUI) to handle input and output for BRYNTRN, these response models can be connected easily and correctly to BRYNTRN in a user friendly way. The GUI for the Acute Radiation Risk and BRYNTRN Organ Dose (ARRBOD) projection code provides seamless integration of input and output manipulations required for operations of the ARRBOD modules: BRYNTRN, SUMDOSE, and the ARR probabilistic response model. The ARRBOD GUI is intended for mission planners, radiation shield designers, space operations in the mission operations directorate (MOD), and space biophysics researchers. Assessment of astronauts organ doses and ARS from the exposure to historically large SPEs is in support of mission design and operation planning to avoid ARS and stay within the current NASA short-term dose limits. The ARRBOD GUI will serve as a proof-of-concept for future integration of other risk projection models for human space applications. We present an overview of the ARRBOD GUI product, which is a new self-contained product, for the major components of the overall system, subsystem interconnections, and external interfaces.

Representative Sinusoids for Hepatic Four-Scale Pharmacokinetics Simulations

PubMed Central

Schwen, Lars Ole; Schenk, Arne; Kreutz, Clemens; Timmer, Jens; Bartolomé Rodríguez, María Matilde; Kuepfer, Lars; Preusser, Tobias

2015-01-01

The mammalian liver plays a key role for metabolism and detoxification of xenobiotics in the body. The corresponding biochemical processes are typically subject to spatial variations at different length scales. Zonal enzyme expression along sinusoids leads to zonated metabolization already in the healthy state. Pathological states of the liver may involve liver cells affected in a zonated manner or heterogeneously across the whole organ. This spatial heterogeneity, however, cannot be described by most computational models which usually consider the liver as a homogeneous, well-stirred organ. The goal of this article is to present a methodology to extend whole-body pharmacokinetics models by a detailed liver model, combining different modeling approaches from the literature. This approach results in an integrated four-scale model, from single cells via sinusoids and the organ to the whole organism, capable of mechanistically representing metabolization inhomogeneity in livers at different spatial scales. Moreover, the model shows circulatory mixing effects due to a delayed recirculation through the surrounding organism. To show that this approach is generally applicable for different physiological processes, we show three applications as proofs of concept, covering a range of species, compounds, and diseased states: clearance of midazolam in steatotic human livers, clearance of caffeine in mouse livers regenerating from necrosis, and a parameter study on the impact of different cell entities on insulin uptake in mouse livers. The examples illustrate how variations only discernible at the local scale influence substance distribution in the plasma at the whole-body level. In particular, our results show that simultaneously considering variations at all relevant spatial scales may be necessary to understand their impact on observations at the organism scale. PMID:26222615

E-Commerce and Business Models

NASA Astrophysics Data System (ADS)

Ogasawara, Yasushi

The development of IT will lead to the integration of computers and networks, and IT will become more function oriented service and result in an indispensable part of the social infrastructure. This means that the critical point will shift from prioritizing “ownership of IS (Information Systems) before anything else” to “how IT will be utilized.” By reaching this technology level, Western origin non-discretion oriented management concept where IT is used as an enabler and IT-based business tools can be flexible enough to accommodate highly discretion oriented practices in Japanese organizations. In other words, IT can finally be utilized in a Japanese way. Taking account of the technological development trend, there is a need to take a macro look at the meaning of the concept of business models, something that has become viewed in the “micro” as patent-related issues. Under such trends, the greater freedom in business design the multipurpose use of IT functions is providing, the more critical a capability in the design of an elaborate business model is becoming.

[Obstacles found in the construction of a democratic and participatory hospital management model].

PubMed

Bernardes, Andrea; Cecílio, Luis Carlos de Oliveira; Nakao, Janete R S; Evora, Yolanda D Martinez

2007-01-01

A path leading to management modernization is based on an approach stressing dialog and discussions of the construction of a healthcare enhancement project whose main characteristic is its emphasis on joint management concepts at all levels. This paper assesses almost ten years of management by committee in a public hospital in Rio de Janeiro State, Brazil, seeking impacts on its micro-policies. The intention is to identify and analyze how the nursing staff experienced the implantation of this management model in the hospital. Empirical matters were analyzed at two levels: initially the comments of the players were grouped into themes, followed by cross-theme readings that analyzed the concept of "noise". The remarks made by the respondents indicated that this "noise" functions within the organization, demonstrating that the selected management process and the manner in which it was conducted are not sufficient to penetrate and intervene in institutional micro-policies, leaving gaps between the proposals set forth by this management model and the real situation of the workers.

The emergence of understanding in a computer model of concepts and analogy-making

NASA Astrophysics Data System (ADS)

Mitchell, Melanie; Hofstadter, Douglas R.

1990-06-01

This paper describes Copycat, a computer model of the mental mechanisms underlying the fluidity and adaptability of the human conceptual system in the context of analogy-making. Copycat creates analogies between idealized situations in a microworld that has been designed to capture and isolate many of the central issues of analogy-making. In Copycat, an understanding of the essence of a situation and the recognition of deep similarity between two superficially different situations emerge from the interaction of a large number of perceptual agents with an associative, overlapping, and context-sensitive network of concepts. Central features of the model are: a high degree of parallelism; competition and cooperation among a large number of small, locally acting agents that together create a global understanding of the situation at hand; and a computational temperature that measures the amount of perceptual organization as processing proceeds and that in turn controls the degree of randomness with which decisions are made in the system.

Modeling relations in nature and eco-informatics: a practical application of rosennean complexity.

PubMed

Kineman, John J

2007-10-01

The purpose of eco-informatics is to communicate critical information about organisms and ecosystems. To accomplish this, it must reflect the complexity of natural systems. Present information systems are designed around mechanistic concepts that do not capture complexity. Robert Rosen's relational theory offers a way of representing complexity in terms of information entailments that are part of an ontologically implicit 'modeling relation'. This relation has corresponding epistemological components that can be captured empirically, the components being structure (associated with model encoding) and function (associated with model decoding). Relational complexity, thus, provides a long-awaited theoretical underpinning for these concepts that ecology has found indispensable. Structural information pertains to the material organization of a system, which can be represented by data. Functional information specifies potential change, which can be inferred from experiment and represented as models or descriptions of state transformations. Contextual dependency (of structure or function) implies meaning. Biological functions imply internalized or system-dependent laws. Complexity can be represented epistemologically by relating structure and function in two different ways. One expresses the phenomenal relation that exists in any present or past instance, and the other draws the ontology of a system into the empirical world in terms of multiple potentials subject to natural forms of selection and optimality. These act as system attractors. Implementing these components and their theoretical relations in an informatics system will provide more-complete ecological informatics than is possible from a strictly mechanistic point of view. This approach will enable many new possibilities for supporting science and decision making.

A generic concept to overcome bandgap limitations for designing highly efficient multi-junction photovoltaic cells

PubMed Central

Guo, Fei; Li, Ning; Fecher, Frank W.; Gasparini, Nicola; Quiroz, Cesar Omar Ramirez; Bronnbauer, Carina; Hou, Yi; Radmilović, Vuk V.; Radmilović, Velimir R.; Spiecker, Erdmann; Forberich, Karen; Brabec, Christoph J.

2015-01-01

The multi-junction concept is the most relevant approach to overcome the Shockley–Queisser limit for single-junction photovoltaic cells. The record efficiencies of several types of solar technologies are held by series-connected tandem configurations. However, the stringent current-matching criterion presents primarily a material challenge and permanently requires developing and processing novel semiconductors with desired bandgaps and thicknesses. Here we report a generic concept to alleviate this limitation. By integrating series- and parallel-interconnections into a triple-junction configuration, we find significantly relaxed material selection and current-matching constraints. To illustrate the versatile applicability of the proposed triple-junction concept, organic and organic-inorganic hybrid triple-junction solar cells are constructed by printing methods. High fill factors up to 68% without resistive losses are achieved for both organic and hybrid triple-junction devices. Series/parallel triple-junction cells with organic, as well as perovskite-based subcells may become a key technology to further advance the efficiency roadmap of the existing photovoltaic technologies. PMID:26177808

A generic concept to overcome bandgap limitations for designing highly efficient multi-junction photovoltaic cells.

PubMed

Guo, Fei; Li, Ning; Fecher, Frank W; Gasparini, Nicola; Ramirez Quiroz, Cesar Omar; Bronnbauer, Carina; Hou, Yi; Radmilović, Vuk V; Radmilović, Velimir R; Spiecker, Erdmann; Forberich, Karen; Brabec, Christoph J

2015-07-16

The multi-junction concept is the most relevant approach to overcome the Shockley-Queisser limit for single-junction photovoltaic cells. The record efficiencies of several types of solar technologies are held by series-connected tandem configurations. However, the stringent current-matching criterion presents primarily a material challenge and permanently requires developing and processing novel semiconductors with desired bandgaps and thicknesses. Here we report a generic concept to alleviate this limitation. By integrating series- and parallel-interconnections into a triple-junction configuration, we find significantly relaxed material selection and current-matching constraints. To illustrate the versatile applicability of the proposed triple-junction concept, organic and organic-inorganic hybrid triple-junction solar cells are constructed by printing methods. High fill factors up to 68% without resistive losses are achieved for both organic and hybrid triple-junction devices. Series/parallel triple-junction cells with organic, as well as perovskite-based subcells may become a key technology to further advance the efficiency roadmap of the existing photovoltaic technologies.

Nanopyroxene Grafting with β-Cyclodextrin Monomer for Wastewater Applications.

PubMed

Nafie, Ghada; Vitale, Gerardo; Carbognani Ortega, Lante; Nassar, Nashaat N

2017-12-06

Emerging nanoparticle technology provides opportunities for environmentally friendly wastewater treatment applications, including those in the large liquid tailings containments in the Alberta oil sands. In this study, we synthesize β-cyclodextrin grafted nanopyroxenes to offer an ecofriendly platform for the selective removal of organic compounds typically present in these types of applications. We carry out computational modeling at the micro level through molecular mechanics and molecular dynamics simulations and laboratory experiments at the macro level to understand the interactions between the synthesized nanomaterials and two-model naphthenic acid molecules (cyclopentanecarboxylic and trans-4-pentylcyclohexanecarboxylic acids) typically existing in tailing ponds. The proof-of-concept computational modeling and experiments demonstrate that monomer grafted nanopyroxene  or nano-AE of the sodium iron-silicate aegirine are found to be promising candidates for the removal of polar organic compounds from wastewater, among other applications. These nano-AE offer new possibilities for treating tailing ponds generated by the oil sands industry.

Change management in health care.

PubMed

Campbell, Robert James

2008-01-01

This article introduces health care managers to the theories and philosophies of John Kotter and William Bridges, 2 leaders in the evolving field of change management. For Kotter, change has both an emotional and situational component, and methods for managing each are expressed in his 8-step model (developing urgency, building a guiding team, creating a vision, communicating for buy-in, enabling action, creating short-term wins, don't let up, and making it stick). Bridges deals with change at a more granular, individual level, suggesting that change within a health care organization means that individuals must transition from one identity to a new identity when they are involved in a process of change. According to Bridges, transitions occur in 3 steps: endings, the neutral zone, and beginnings. The major steps and important concepts within the models of each are addressed, and examples are provided to demonstrate how health care managers can actualize the models within their health care organizations.

Dynamic Business Networks: A Headache for Sustainable Systems Interoperability

NASA Astrophysics Data System (ADS)

Agostinho, Carlos; Jardim-Goncalves, Ricardo

Collaborative networked environments emerged with the spread of the internet, contributing to overcome past communication barriers, and identifying interoperability as an essential property. When achieved seamlessly, efficiency is increased in the entire product life cycle. Nowadays, most organizations try to attain interoperability by establishing peer-to-peer mappings with the different partners, or in optimized networks, by using international standard models as the core for information exchange. In current industrial practice, mappings are only defined once, and the morphisms that represent them, are hardcoded in the enterprise systems. This solution has been effective for static environments, where enterprise and product models are valid for decades. However, with an increasingly complex and dynamic global market, models change frequently to answer new customer requirements. This paper draws concepts from the complex systems science and proposes a framework for sustainable systems interoperability in dynamic networks, enabling different organizations to evolve at their own rate.

Functional tooth restoration by next-generation bio-hybrid implant as a bio-hybrid artificial organ replacement therapy

PubMed Central

Oshima, Masamitsu; Inoue, Kaoru; Nakajima, Kei; Tachikawa, Tetsuhiko; Yamazaki, Hiromichi; Isobe, Tomohide; Sugawara, Ayaka; Ogawa, Miho; Tanaka, Chie; Saito, Masahiro; Kasugai, Shohei; Takano-Yamamoto, Teruko; Inoue, Takashi; Tezuka, Katsunari; Kuboki, Takuo; Yamaguchi, Akira; Tsuji, Takashi

2014-01-01

Bio-hybrid artificial organs are an attractive concept to restore organ function through precise biological cooperation with surrounding tissues in vivo. However, in bio-hybrid artificial organs, an artificial organ with fibrous connective tissues, including muscles, tendons and ligaments, has not been developed. Here, we have enveloped with embryonic dental follicle tissue around a HA-coated dental implant, and transplanted into the lower first molar region of a murine tooth-loss model. We successfully developed a novel fibrous connected tooth implant using a HA-coated dental implant and dental follicle stem cells as a bio-hybrid organ. This bio-hybrid implant restored physiological functions, including bone remodelling, regeneration of severe bone-defect and responsiveness to noxious stimuli, through regeneration with periodontal tissues, such as periodontal ligament and cementum. Thus, this study represents the potential for a next-generation bio-hybrid implant for tooth loss as a future bio-hybrid artificial organ replacement therapy. PMID:25116435

Leveraging biomedical ontologies and annotation services to organize microbiome data from Mammalian hosts.

PubMed

Sarkar, Indra Neil

2010-11-13

A better understanding of commensal microbiotic communities ("microbiomes") may provide valuable insights to human health. Towards this goal, an essential step may be the development of approaches to organize data that can enable comparative hypotheses across mammalian microbiomes. The present study explores the feasibility of using existing biomedical informatics resources - especially focusing on those available at the National Center for Biomedical Ontology - to organize microbiome data contained within large sequence repositories, such as GenBank. The results indicate that the Foundational Model of Anatomy and SNOMED CT can be used to organize greater than 90% of the bacterial organisms associated with 10 domesticated mammalian species. The promising findings suggest that the current biomedical informatics infrastructure may be used towards the organizing of microbiome data beyond humans. Furthermore, the results identify key concepts that might be organized into a semantic structure for incorporation into subsequent annotations that could facilitate comparative biomedical hypotheses pertaining to human health.

Knowledge of the brain-death concept among secondary school teachers.

PubMed

Ríos, A; Febrero, B; López-Navas, A; Martínez-Alarcón, L; Sánchez, J; Guzmán, D; Ramírez, P; Parrilla, P

2012-01-01

The concept of brain death (BD) is not very well known in the population, and its unknown nature is one of the main factors that could lead to an attitude against organ donation. The teaching sector has an important influence on the education of adolescents, and for this reason the teacher's knowledge of these concepts is fundamental to spread the correct meaning of the concept to young people. To analyze the concept of BD among teachers of compulsory secondary education (CSE) in southeast Spain and to determine teachers' influence on attitude toward organ donation. Ten CSE level schools were selected and stratified according to geographical location in southeast spain. A random sample was taken of CSE teachers. The knowledge of the concept of BD and attitude toward donation were analyzed using a validated questionnaire, which was self-administered and completed anonymously. Sixty-four percent (n = 180) of respondents knew the BD concept and they considered it to be the death of an individual. Of the rest, 34% (n = 95) did not know this concept, and the remaining 3% (n = 8) believed it did not mean a person's death. Those who understood the concept of BD were more in favor of deceased donation than those who held the wrong concept (82% versus 75%; P < .01). The knowledge of the concept of BD is associated with variables directly and indirectly related with donation and transplantation (P < .05). A third of the CSE teaching staff did not know or understand the BD concept as the death of an individual. The knowledge of BD positively affects attitude toward organ donation. Given that teachers are a source of information, the basic training of CSE teaching staff in basic concepts such as BD would be important. Copyright © 2012 Elsevier Inc. All rights reserved.

[Organization of clinical emergency units. Mission and environmental factors determine the organizational concept].

PubMed

Genewein, U; Jakob, M; Bingisser, R; Burla, S; Heberer, M

2009-02-01

Mission and organization of emergency units were analysed to understand the underlying principles and concepts. The recent literature (2000-2007) on organizational structures and functional concepts of clinical emergency units was reviewed. An organizational portfolio based on the criteria specialization (presence of medical specialists on the emergency unit) and integration (integration of the emergency unit into the hospital structure) was established. The resulting organizational archetypes were comparatively assessed based on established efficiency criteria (efficiency of resource utilization, process efficiency, market efficiency). Clinical emergency units differ with regard to autonomy (within the hospital structure), range of services and service depth (horizontal and vertical integration). The "specialization"-"integration"-portfolio enabled the definition of typical organizational patterns (so-called archetypes): profit centres primarily driven by economic objectives, service centres operating on the basis of agreements with the hospital board, functional clinical units integrated into medical specialty units (e.g., surgery, gynaecology) and modular organizations characterized by small emergency teams that would call specialists immediately after triage and initial diagnostic. There is no "one fits all" concept for the organization of clinical emergency units. Instead, a number of well characterized organizational concepts are available enabling a rational choice based on a hospital's mission and demand.

The Arizona Telemedicine Program business model.

PubMed

Barker, Gail P; Krupinski, Elizabeth A; McNeely, Richard A; Holcomb, Michael J; Lopez, Ana Maria; Weinstein, Ronald S

2005-01-01

The Arizona Telemedicine Program (ATP) was established in 1996 when state funding was provided to implement eight telemedicine sites. Since then the ATP has expanded to connect 55 health-care organizations through a membership programme formalized through legal contracts. The ATP's membership model is based on an application service provider (ASP) concept, whereby organizations can share services at lower cost; that is, the ATP acts as a broker for services. The membership fee schedule is flexible, allowing clients to purchase only those services desired. An annual membership fee is paid by every user, based on the services requested. The membership programme income has provided a steady revenue stream for the ATP. The membership-derived revenue represented 30% of the ATP's 2.6 million dollars total income during fiscal year 2003/04.

High Reliability Organizations--Medication Safety.

PubMed

Yip, Luke; Farmer, Brenna

2015-06-01

High reliability organizations (HROs), such as the aviation industry, successfully engage in high-risk endeavors and have low incidence of adverse events. HROs have a preoccupation with failure and errors. They analyze each event to effect system wide change in an attempt to mitigate the occurrence of similar errors. The healthcare industry can adapt HRO practices, specifically with regard to teamwork and communication. Crew resource management concepts can be adapted to healthcare with the use of certain tools such as checklists and the sterile cockpit to reduce medication errors. HROs also use The Swiss Cheese Model to evaluate risk and look for vulnerabilities in multiple protective barriers, instead of focusing on one failure. This model can be used in medication safety to evaluate medication management in addition to using the teamwork and communication tools of HROs.

A Network Model of the Emotional Brain.

PubMed

Pessoa, Luiz

2017-05-01

Emotion is often understood in terms of a circumscribed set of cortical and subcortical brain regions. I propose, instead, that emotion should be understood in terms of large-scale network interactions spanning the entire neuroaxis. I describe multiple anatomical and functional principles of brain organization that lead to the concept of 'functionally integrated systems', cortical-subcortical systems that anchor the organization of emotion in the brain. The proposal is illustrated by describing the cortex-amygdala integrated system and how it intersects with systems involving the ventral striatum/accumbens, septum, hippocampus, hypothalamus, and brainstem. The important role of the thalamus is also highlighted. Overall, the model clarifies why the impact of emotion is wide-ranging, and how emotion is interlocked with perception, cognition, motivation, and action. Copyright © 2017 Elsevier Ltd. All rights reserved.

Standardized data collection to build prediction models in oncology: a prototype for rectal cancer.

PubMed

Meldolesi, Elisa; van Soest, Johan; Damiani, Andrea; Dekker, Andre; Alitto, Anna Rita; Campitelli, Maura; Dinapoli, Nicola; Gatta, Roberto; Gambacorta, Maria Antonietta; Lanzotti, Vito; Lambin, Philippe; Valentini, Vincenzo

2016-01-01

The advances in diagnostic and treatment technology are responsible for a remarkable transformation in the internal medicine concept with the establishment of a new idea of personalized medicine. Inter- and intra-patient tumor heterogeneity and the clinical outcome and/or treatment's toxicity's complexity, justify the effort to develop predictive models from decision support systems. However, the number of evaluated variables coming from multiple disciplines: oncology, computer science, bioinformatics, statistics, genomics, imaging, among others could be very large thus making traditional statistical analysis difficult to exploit. Automated data-mining processes and machine learning approaches can be a solution to organize the massive amount of data, trying to unravel important interaction. The purpose of this paper is to describe the strategy to collect and analyze data properly for decision support and introduce the concept of an 'umbrella protocol' within the framework of 'rapid learning healthcare'.

A Flipped Pedagogy for Expert Problem Solving

NASA Astrophysics Data System (ADS)

Pritchard, David

The internet provides free learning opportunities for declarative (Wikipedia, YouTube) and procedural (Kahn Academy, MOOCs) knowledge, challenging colleges to provide learning at a higher cognitive level. Our ``Modeling Applied to Problem Solving'' pedagogy for Newtonian Mechanics imparts strategic knowledge - how to systematically determine which concepts to apply and why. Declarative and procedural knowledge is learned online before class via an e-text, checkpoint questions, and homework on edX.org (see http://relate.mit.edu/physicscourse); it is organized into five Core Models. Instructors then coach students on simple ``touchstone problems'', novel exercises, and multi-concept problems - meanwhile exercising three of the four C's: communication, collaboration, critical thinking and problem solving. Students showed 1.2 standard deviations improvement on the MIT final exam after three weeks instruction, a significant positive shift in 7 of the 9 categories in the CLASS, and their grades improved by 0.5 standard deviation in their following physics course (Electricity and Magnetism).

The Science of Transportation Analysis and Simulation

NASA Astrophysics Data System (ADS)

Gleibe, John

2010-03-01

Transportation Science focuses on methods developed to model and analyze the interaction between human behavior and transportation systems. From the human behavioral, or demand, perspective, we are interested in how person and households organize their activities across space and time, with travel viewed as an enabling activity. We have a particular interest in how to model the range of responses to public policy and transportation system changes, which leads to the consideration of both short- and long-term decision-making, interpersonal dependencies, and non-transportation-related opportunities and constraints, including household budgets, land use systems and economic systems. This has led to the development of complex structural econometric modeling systems as well as agent-based simulations. From the transportation systems, or supply, perspective we are interested in the level of service provide by transportation facilities, be it auto, transit or multi-modal systems. This has led to the development of network models and equilibrium concepts as well as hybrid simulation systems based on concepts borrowed from physics, such as fluid flow models, and cellular automata-type models. In this presentation, we review a representative sample of these methods and their use in transportation planning and public policy analysis.

[Liability for medical malpractice: an economic approach].

PubMed

Carles, M

2003-01-01

In recent years, changes in the organization of healthcare institutions and the increased number of medical malpractice claims have revealed the need to study the concept of medical responsibility and the repercussion of these changes on healthcare provision. To date, discussion has focussed on legal aspects and economic implications have been largely ignored.The present article reviews studies that have performed an economic analysis the subject. Firstly, we examine studies that gradually introduce the concepts of uncertainty, risk aversion and moral hazard. Secondly, in the healthcare environment, we pay particular attention to models that include new arguments on professionals' objective duties or to bargaining models when there is asymmetric information. Finally, we consider the medical malpractice insurance market and investigate how reputation and the possibilities of exercising defensive medicine influence healthcare provision. Our analysis suggests that, due to the characteristics of the healthcare market, the models proposed by the economy of information are very useful for performing economic analyses of liability in medical malpractice. However, alternative hypotheses also need to be formulated so that these models can be adapted to the specific characteristics of different health systems.

What Should We Include in a Cultural Competence Curriculum? An Emerging Formative Evaluation Process to Foster Curriculum Development

PubMed Central

Crenshaw, Katie; Shewchuk, Richard M.; Qu, Haiyan; Staton, Lisa J.; Bigby, Judy Ann; Houston, Thomas K.; Allison, Jeroan; Estrada, Carlos A.

2011-01-01

Purpose To identify, prioritize, and organize components of a cultural competence curriculum to address disparities in cardiovascular disease. Method In 2006, four separate nominal group technique sessions were conducted with medical students, residents, community physicians, and academic physicians to generate and prioritize a list of concepts (i.e., ideas) to include in a curriculum. Afterward, 45 educators and researchers organized and prioritized the concepts using a card-sorting exercise. Multidimensional scaling (MDS) and hierarchical cluster analysis produced homogeneous groupings of related concepts and generated a cognitive map. The main outcome measures were the number of cultural competence concepts, their relative ranks, and the cognitive map. Results Thirty participants generated 61 concepts, 29 were identified by at least 2 participants. The cognitive map organized concepts into four clusters, interpreted as: (1) patient’s cultural background (e.g.,, information on cultures, habits, values); (2) provider and health care (e.g., clinical skills, awareness of one’s bias, patient-centeredness, and professionalism), communication skills (e.g., history, stereotype avoidance, and health disparities epidemiology); (3) cross-culture (e.g., idiomatic expressions, examples of effective communication); and (4) resources to manage cultural diversity (e.g., translator guides, instructions and community resources). The MDS two-dimensional solution demonstrated a good fit (stress=0.07; R2=0.97). Conclusions A novel, combined approach allowed stakeholders’ inputs to identify and cognitively organize critical domains used to guide development of a cultural competence curriculum. Educators may use this approach to develop and organize educational content for their target audiences, especially in ill-defined areas like cultural competence. PMID:21248602

Development and Effectiveness of an Educational Card Game as Supplementary Material in Understanding Selected Topics in Biology

PubMed Central

Gutierrez, Arnel F.

2014-01-01

The complex concepts and vocabulary of biology classes discourage many students. In this study, a pretest–posttest model was used to test the effectiveness of an educational card game in reinforcing biological concepts in comparison with traditional teaching methods. The subjects of this study were two biology classes at Bulacan State University–Sarmiento Campus. Both classes received conventional instruction; however, the experimental group's instruction was supplemented with the card game, while the control group's instruction was reinforced with traditional exercises and assignments. The score increases from pretest to posttest showed that both methods effectively reinforced biological concepts, but a t test showed that the card game is more effective than traditional teaching methods. Additionally, students from the experimental group evaluated the card game using five criteria: goals, design, organization, playability, and usefulness. The students rated the material very satisfactory. PMID:24591506

A glossary for dissemination and implementation research in health.

PubMed

Rabin, Borsika A; Brownson, Ross C; Haire-Joshu, Debra; Kreuter, Matthew W; Weaver, Nancy L

2008-01-01

Dissemination and implementation (D&I) Research is increasingly Recognized as an important function of academia and is a growing priority for major health-related funders. Because D&I Research in the health field has emerged from Research traditions in diverse disciplines Ranging from agriculture to education, there are inconsistencies in the use and meaning of terms and main concepts. This glossary provides definitions for the key concepts and terms of D&I Research in health (in both public health and clinical settings). Definitions are organized under five major sections: (1) foundation concepts; (2) types of Research; (3) models, theories, and frameworks; (4) factors influencing the D&I processes; and (5) measurement/evaluation of the D&I process. The aim of this glossary is to aid in the development of more standardized and established terminology for D&I Research, facilitate the communication across different stakeholders, and ultimately contribute to higher-quality D&I Research.

Development and effectiveness of an educational card game as supplementary material in understanding selected topics in biology.

PubMed

Gutierrez, Arnel F

2014-01-01

The complex concepts and vocabulary of biology classes discourage many students. In this study, a pretest-posttest model was used to test the effectiveness of an educational card game in reinforcing biological concepts in comparison with traditional teaching methods. The subjects of this study were two biology classes at Bulacan State University-Sarmiento Campus. Both classes received conventional instruction; however, the experimental group's instruction was supplemented with the card game, while the control group's instruction was reinforced with traditional exercises and assignments. The score increases from pretest to posttest showed that both methods effectively reinforced biological concepts, but a t test showed that the card game is more effective than traditional teaching methods. Additionally, students from the experimental group evaluated the card game using five criteria: goals, design, organization, playability, and usefulness. The students rated the material very satisfactory.

Teaching cultural competence using an exemplar from literary journalism.

PubMed

Anderson, Kathryn L

2004-06-01

Fadiman's work of literary journalism, The Spirit Catches You and You Fall Down, was used as a case study to teach transcultural and other nursing concepts to undergraduate nursing students. Campinha-Bacote's model of cultural competence was used to organize transcultural nursing concepts in the course. Before and after the course, students completed assessments consisting of two cultural attitude questionnaires and a paper describing a personal experience with adherence and failure to adhere by a Mexican American client. After reading Fadiman's book and completing several short writing assignments examining key course concepts, student scores on the questionnaires were mostly unchanged. However, students demonstrated growth in cultural awareness and skill in their "after" papers. Results suggest that valid, reliable tools are needed to detect changes in cultural competence. Qualitative data suggest that students can begin the process of becoming culturally competent through the creative use of literature in nursing education.

Making the case for evidence-based design in healthcare: a descriptive case study of organizational decision making.

PubMed

Shoemaker, Lorie K; Kazley, Abby Swanson; White, Andrea

2010-01-01

The aim of this study was to describe the organizational decision-making process used in the selection of evidence-based design (EBD) concepts, the criteria used to make these decisions, and the extent to which leadership style may have influenced the decision-making process. Five research questions were formulated to frame the direction of this study, including: (1) How did healthcare leaders learn of innovations in design? (2) How did healthcare leaders make decisions in the selection of healthcare design concepts? (3) What criteria did healthcare leaders use in the decision-making process? (4) How did healthcare leaders consider input from the staff in design decisions? and (5) To what extent did the leadership style of administrators affect the outcomes of the decision-making process? Current issues affecting healthcare in the community led the principal investigator's organization to undertake an ambitious facilities expansion project. As part of its planning process, the organization learned of EBD principles that seemingly had a positive impact on patient care and safety and staff working conditions. Although promising, a paucity of empirical research addressed the cost/benefit of incorporating many EBD concepts into one hospital setting, and there was no research that articulated the organizational decision-making process used by healthcare administrators when considering the use of EBD in expansion projects. A mixed-method, descriptive, qualitative, single-case study and quantitative design were used to address the five research questions. The Systems Research Organizing Model provided the theoretical framework. A variety of data collection methods was used, including interviews of key respondents, the review of documentary evidence, and the Multifactor Leadership Questionnaire. A participatory process was used throughout the design decision phases, involving staff at all levels of the organization. The Internet and architects facilitated learning about EBD. Financial considerations were a factor in decision making. The prevalence of the transformational leadership style among the organization's administrators exceeded the U.S. mean.

Hierarchical Parallelism in Finite Difference Analysis of Heat Conduction

NASA Technical Reports Server (NTRS)

Padovan, Joseph; Krishna, Lala; Gute, Douglas

1997-01-01

Based on the concept of hierarchical parallelism, this research effort resulted in highly efficient parallel solution strategies for very large scale heat conduction problems. Overall, the method of hierarchical parallelism involves the partitioning of thermal models into several substructured levels wherein an optimal balance into various associated bandwidths is achieved. The details are described in this report. Overall, the report is organized into two parts. Part 1 describes the parallel modelling methodology and associated multilevel direct, iterative and mixed solution schemes. Part 2 establishes both the formal and computational properties of the scheme.

Metabolic Network Modeling for Computer-Aided Design of Microbial Interactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Song, Hyun-Seob; Nelson, William C.; Lee, Joon-Yong

Interest in applying microbial communities to biotechnology continues to increase. Successful engineering of microbial communities requires a fundamental shift in focus from enhancing metabolic capabilities in individual organisms to promoting synergistic interspecies interactions. This goal necessitates in silico tools that provide a predictive understanding of how microorganisms interact with each other and their environments. In this regard, we highlight a need for a new concept that we have termed biological computer-aided design of interactions (BioCADi). We ground this discussion within the context of metabolic network modeling.

Concept Teaching in Instrumental Music Education: A Literature Review

ERIC Educational Resources Information Center

Tan, Leonard

2017-01-01

This article is a review of research literature on the teaching of concepts in instrumental music education. It is organized in four parts (a) the value of concept teaching in large instrumental ensembles, (b) time spent teaching concepts during rehearsals, (c) approaches to concept teaching, and (d) implications for music education. Research has…

Experimental basis for a Titan probe organic analysis

NASA Technical Reports Server (NTRS)

Mckay, C. P.; Scattergood, T. W.; Borucki, W. J.; Kasting, J. F.; Miller, S. L.

1986-01-01

The recent Voyager flyby of Titan produced evidence for at least nine organic compounds in that atmosphere that are heavier than methane. Several models of Titan's atmosphere, as well as laboratory simulations, suggest the presence of organics considerably more complex that those observed. To ensure that the in situ measurements are definitive with respect to Titan's atmosphere, experiment concepts, and the related instrumentation, must be carefully developed specifically for such a mission. To this end, the possible composition of the environment to be analyzed must be bracketed and model samples must be provided for instrumentation development studies. Laboratory studies to define the optimum flight experiment and sampling strategy for a Titan entry probe are currently being conducted. Titan mixtures are being subjected to a variety of energy sources including high voltage electron from a DC discharge, high current electric shock, and laser detonation. Gaseous and solid products are produced which are then analyzed. Samples from these experiements are also provided to candidate flight experiments as models for instrument development studies. Preliminary results show that existing theoretical models for chemistry in Titan's atmosphere cannot adequetely explain the presence and abundance of all trace gases observed in these experiments.

JPL Innovation Foundry

NASA Technical Reports Server (NTRS)

Sherwood, Brent; McCleese, Daniel

2012-01-01

Space science missions are increasingly challenged today: in ambition, by increasingly sophisticated hypotheses tested; in development, by the increasing complexity of advanced technologies; in budgeting, by the decline of flagship-class mission opportunities; in management, by expectations for breakthrough science despite a risk-averse programmatic climate; and in planning, by increasing competition for scarce resources. How are the space-science missions of tomorrow being formulated? The paper describes the JPL Innovation Foundry, created in 2011, to respond to this evolving context. The Foundry integrates methods, tools, and experts that span the mission concept lifecycle. Grounded in JPL's heritage of missions, flight instruments, mission proposals, and concept innovation, the Foundry seeks to provide continuity of support and cost-effective, on-call access to the right domain experts at the right time, as science definition teams and Principal Investigators mature mission ideas from "cocktail napkin" to PDR. The Foundry blends JPL capabilities in proposal development and concurrent engineering, including Team X, with new approaches for open-ended concept exploration in earlier, cost-constrained phases, and with ongoing research and technology projects. It applies complexity and cost models, projectformulation lessons learned, and strategy analyses appropriate to each level of concept maturity. The Foundry is organizationally integrated with JPL formulation program offices; staffed by JPL's line organizations for engineering, science, and costing; and overseen by senior Laboratory leaders to assure experienced coordination and review. Incubation of each concept is tailored depending on its maturity and proposal history, and its highest leverage modeling and analysis needs.

Interkulturelles Lernen — Zur Grundlegung eines didaktischen Prinzips interkultureller Begegnungen

NASA Astrophysics Data System (ADS)

Sandhaas, Bernd

1988-12-01

In the Federal Republic of Germany there have in recent years been many varied encounters between Germans and representatives of other cultures, particularly those from Third World countries. These have increasingly been organized with an awareness of global interdependence and have as a result opened the door to the influence of foreign cultures and to an unmistakeable movement in the direction of a multicultural society. An intercultural pedagogical approach and didactic theory are faced with the task of resolving the consequent problems related to education and training. The author firstly attempts to systematize as a typology the practice of learning as it occurs in intercultural encounters in so far as this relates to the Federal Republic of Germany. He suggests that `intercultural learning' should be seen as the didactic principle underlying the organization of learning in such encounters. Through a detailed discussion of his central concepts of `culture' and `learning' and of the issue of `interculturalism', and by sketching a theoretical model of the stages and goals of the learning taking place, he then makes plain the necessary enlargement of the German concept of `Kultur' and the process of differentiation which the concept of learning will have to engage in if it is to be applicable to educational activity in international or intercultural contexts.

Knowledge Space: A Conceptual Basis for the Organization of Knowledge

ERIC Educational Resources Information Center

Meincke, Peter P. M.; Atherton, Pauline

1976-01-01

Proposes a new conceptual basis for visualizing the organization of information, or knowledge, which differentiates between the concept "vectors" for a field of knowledge represented in a multidimensional space, and the state "vectors" for a person based on his understanding of these concepts, and the representational…

Curriculum Handbook for School Executives.

ERIC Educational Resources Information Center

Ellena, William J., Ed.

In this book, specialists and organizations identify the emerging concepts in curriculum for their particular fields, the emerging concepts in the organization and application of knowledge, and the emerging methods of instruction. One chapter each is devoted to a discussion of (1) adult education, (2) art education, (3) business education, (4)…

Population-reaction model and microbial experimental ecosystems for understanding hierarchical dynamics of ecosystems.

PubMed

Hosoda, Kazufumi; Tsuda, Soichiro; Kadowaki, Kohmei; Nakamura, Yutaka; Nakano, Tadashi; Ishii, Kojiro

2016-02-01

Understanding ecosystem dynamics is crucial as contemporary human societies face ecosystem degradation. One of the challenges that needs to be recognized is the complex hierarchical dynamics. Conventional dynamic models in ecology often represent only the population level and have yet to include the dynamics of the sub-organism level, which makes an ecosystem a complex adaptive system that shows characteristic behaviors such as resilience and regime shifts. The neglect of the sub-organism level in the conventional dynamic models would be because integrating multiple hierarchical levels makes the models unnecessarily complex unless supporting experimental data are present. Now that large amounts of molecular and ecological data are increasingly accessible in microbial experimental ecosystems, it is worthwhile to tackle the questions of their complex hierarchical dynamics. Here, we propose an approach that combines microbial experimental ecosystems and a hierarchical dynamic model named population-reaction model. We present a simple microbial experimental ecosystem as an example and show how the system can be analyzed by a population-reaction model. We also show that population-reaction models can be applied to various ecological concepts, such as predator-prey interactions, climate change, evolution, and stability of diversity. Our approach will reveal a path to the general understanding of various ecosystems and organisms. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

Unifying screening processes within the PROSPR consortium: a conceptual model for breast, cervical, and colorectal cancer screening.

PubMed

Beaber, Elisabeth F; Kim, Jane J; Schapira, Marilyn M; Tosteson, Anna N A; Zauber, Ann G; Geiger, Ann M; Kamineni, Aruna; Weaver, Donald L; Tiro, Jasmin A

2015-06-01

General frameworks of the cancer screening process are available, but none directly compare the process in detail across different organ sites. This limits the ability of medical and public health professionals to develop and evaluate coordinated screening programs that apply resources and population management strategies available for one cancer site to other sites. We present a trans-organ conceptual model that incorporates a single screening episode for breast, cervical, and colorectal cancers into a unified framework based on clinical guidelines and protocols; the model concepts could be expanded to other organ sites. The model covers four types of care in the screening process: risk assessment, detection, diagnosis, and treatment. Interfaces between different provider teams (eg, primary care and specialty care), including communication and transfer of responsibility, may occur when transitioning between types of care. Our model highlights across each organ site similarities and differences in steps, interfaces, and transitions in the screening process and documents the conclusion of a screening episode. This model was developed within the National Cancer Institute-funded consortium Population-based Research Optimizing Screening through Personalized Regimens (PROSPR). PROSPR aims to optimize the screening process for breast, cervical, and colorectal cancer and includes seven research centers and a statistical coordinating center. Given current health care reform initiatives in the United States, this conceptual model can facilitate the development of comprehensive quality metrics for cancer screening and promote trans-organ comparative cancer screening research. PROSPR findings will support the design of interventions that improve screening outcomes across multiple cancer sites. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Animal models and conserved processes

PubMed Central

2012-01-01

Background The concept of conserved processes presents unique opportunities for using nonhuman animal models in biomedical research. However, the concept must be examined in the context that humans and nonhuman animals are evolved, complex, adaptive systems. Given that nonhuman animals are examples of living systems that are differently complex from humans, what does the existence of a conserved gene or process imply for inter-species extrapolation? Methods We surveyed the literature including philosophy of science, biological complexity, conserved processes, evolutionary biology, comparative medicine, anti-neoplastic agents, inhalational anesthetics, and drug development journals in order to determine the value of nonhuman animal models when studying conserved processes. Results Evolution through natural selection has employed components and processes both to produce the same outcomes among species but also to generate different functions and traits. Many genes and processes are conserved, but new combinations of these processes or different regulation of the genes involved in these processes have resulted in unique organisms. Further, there is a hierarchy of organization in complex living systems. At some levels, the components are simple systems that can be analyzed by mathematics or the physical sciences, while at other levels the system cannot be fully analyzed by reducing it to a physical system. The study of complex living systems must alternate between focusing on the parts and examining the intact whole organism while taking into account the connections between the two. Systems biology aims for this holism. We examined the actions of inhalational anesthetic agents and anti-neoplastic agents in order to address what the characteristics of complex living systems imply for inter-species extrapolation of traits and responses related to conserved processes. Conclusion We conclude that even the presence of conserved processes is insufficient for inter-species extrapolation when the trait or response being studied is located at higher levels of organization, is in a different module, or is influenced by other modules. However, when the examination of the conserved process occurs at the same level of organization or in the same module, and hence is subject to study solely by reductionism, then extrapolation is possible. PMID:22963674

Evolving Ideas on the Origin and Evolution of Flowers: New Perspectives in the Genomic Era

PubMed Central

Chanderbali, Andre S.; Berger, Brent A.; Howarth, Dianella G.; Soltis, Pamela S.; Soltis, Douglas E.

2016-01-01

The origin of the flower was a key innovation in the history of complex organisms, dramatically altering Earth’s biota. Advances in phylogenetics, developmental genetics, and genomics during the past 25 years have substantially advanced our understanding of the evolution of flowers, yet crucial aspects of floral evolution remain, such as the series of genetic and morphological changes that gave rise to the first flowers; the factors enabling the origin of the pentamerous eudicot flower, which characterizes ∼70% of all extant angiosperm species; and the role of gene and genome duplications in facilitating floral innovations. A key early concept was the ABC model of floral organ specification, developed by Elliott Meyerowitz and Enrico Coen and based on two model systems, Arabidopsis thaliana and Antirrhinum majus. Yet it is now clear that these model systems are highly derived species, whose molecular genetic-developmental organization must be very different from that of ancestral, as well as early, angiosperms. In this article, we will discuss how new research approaches are illuminating the early events in floral evolution and the prospects for further progress. In particular, advancing the next generation of research in floral evolution will require the development of one or more functional model systems from among the basal angiosperms and basal eudicots. More broadly, we urge the development of “model clades” for genomic and evolutionary-developmental analyses, instead of the primary use of single “model organisms.” We predict that new evolutionary models will soon emerge as genetic/genomic models, providing unprecedented new insights into floral evolution. PMID:27053123

Comprehensive change management concepts. Development of a participatory approach.

PubMed

Zink, Klaus J; Steimle, Ulrich; Schröder, Delia

2008-07-01

During the last years, many change projects in organizations did not have the planned success. Therefore at first, the causes for these failures and the success factors contributing to organizational change have to be discussed. To get better results, a comprehensive change management concept has been developed and tested in an ongoing research project. By using concepts for an integrated assessment and design of organizations, an approach for analyzing the current situation has been elaborated to identify "lack of integration" in the change initiatives of a company. To realize an integrated overall approach of modernization by harmonizing different methods and concepts, first, one has to prove their relationship to policy and strategy (vertical harmonization). The second step is to take into account the fact that there has to be a logical fit between the single concepts (horizontal harmonization). But even if all elements are logically coherent, that does not mean that the people working in the company also see this coherence. Therefore, in addition to the "logical fit", one has to examine the "psychological fit". In the end, a concept for analyzing the status quo in an organization as a result of "objective data" and "subjective data" originated. Subsequently, instruments for harmonizing different modernizing concepts have been applied. As part of the comprehensive change management concept participatory ergonomic approaches have been used during the project. The present study shows this approach in the case of one company.

Organization of the concepts of the Platonic dialogue Parmenides into a software ontology

NASA Astrophysics Data System (ADS)

Dendrinos, Markos

2015-02-01

This paper concerns with the creation of a knowledge management ontology (in the open source OWL/ Protégé environment), including all the concepts and both the explicit and impicit relations between the concepts met in the Platonic dialogue Parmenides. The selected part of Parmenides is the second half (137c4-166c6), where Parmenides undertakes to take on the challenge of exposing a Zenonian type argumentation concerning the properties of one and being. The incorporation of the Platonic concepts and relations to a software ontology gives the opportunity to organize the philosophical ideas of a certain context in an hierarchical tree enriched with the various defined relations, detect possible logical inconsistencies and produce automatically further concept relations.

"I like to Treat Others as Others Would Treat Me": The Development of Prosocial Selves in an Urban Youth Organization

ERIC Educational Resources Information Center

Deutsch, Nancy L.

2005-01-01

The field of moral development has moved toward an identity-based model suggesting that moral action stems not only from moral reasoning but from a desire to act in ways consistent with one's self-concept. Moral identity, in turn, is rooted in social relationships. This idea, that one's sense of self drives moral behavior and that this identity is…

A Planning Study to Determine the Feasibility of Developing a New Business and Office Education Curriculum. Moonshot--An Office Occupation Curriculum. Final Report.

ERIC Educational Resources Information Center

Lanham, Frank W.

The purpose of this study was to explore the feasibility of utilizing the systems approach in developing an office occupations curriculum congruent with the concepts in the organic curriculum theory. The title of this project is New Office and Business Education Learning System (NOBELS). An analog system model was developed as the framework in…

Modeling Human Elements of Decision-Making

DTIC Science & Technology

2002-06-01

59 LIST OF REFERENCES Agor , Weston H ., The Logic of Intuitive Decision Making, Greenwood Press 1998 Barrick, M., Mount, M., "The Big Five...of sources discuss the concept of intuition. In The Logic of Intuitive Decision-making, Weston Agor refers to intuition as a highly rational...both factual and feeling 16 cues. Agor studied over 3000 individuals in leadership positions in a variety of organizations to determine the role

Deterrence Impact Modeling Environment (DIME) Proof-of-Concept Test Evaluations and Findings

DTIC Science & Technology

2016-06-01

sources of this caution: financial, technical, legal, and ethical . Several current Coast Guard policies complicate ongoing engagement with and assessment...and ethical . There is evidence that several of the stakeholder communities most important to the Coast Guard have not been early adopters of the...self-organization) or longer-term outcomes (such as over-harvesting, regeneration of biodiversity, resilience of an ecological system to human nature

A New Concept Map Model for E-Learning Environments

NASA Astrophysics Data System (ADS)

Dattolo, Antonina; Luccio, Flaminia L.

Web-based education enables learners and teachers to access a wide quantity of continuously updated educational sources. In order to support the learning process, a system has to provide some fundamental features, such as simple mechanisms for the identification of the collection of “interesting” documents, adequate structures for storing, organizing and visualizing these documents, and appropriate mechanisms for creating personalized adaptive paths and views for learners.

AggModel: A soil organic matter model with measurable pools for use in incubation studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Segoli, Moran; De Gryze, S.; Dou, Fugen

2013-01-01

Current soil organic matter (SOM) models are empirical in nature by employing few conceptual SOM pools that have a specific turnover time, but that are not measurable and have no direct relationship with soil structural properties. Most soil particles are held together in aggregates and the number, size and stability of these aggregates significantly affect the size and amount of organic matter contained in these aggregates, and its susceptibility to decomposition. While it has been shown that soil aggregates and their dynamics can be measured directly in the laboratory and in the field, the impact of soil aggregate dynamics onmore » SOM decomposition has not been explicitly incorporated in ecosystem models. Here, we present AggModel, a conceptual and simulation model that integrates soil aggregate and SOM dynamics. In AggModel, we consider unaggregated and microaggregated soil that can exist within or external to macroaggregated soil. Each of the four aggregate size classes contains particulate organic matter and mineral-associated organic matter fractions. We used published data from laboratory incubations to calibrate and validate the biological and environmental effects on the rate of formation and breakdown of macroaggregates and microaggregates, and the organic matter dynamics within these different aggregate fractions. After calibration, AggModel explained more than 70% of the variation in aggregate masses and over 90% of the variation in aggregate-associated carbon. The model estimated the turnover time of macroaggregates as 32 days and 166 days for microaggregates. Sensitivity analysis of AggModel parameterization supported the notion that macroaggregate turnover rate has a strong control over microaggregate masses and, hence, carbon sequestration. In addition to AggModel being a proof-of-concept, the advantage of a model that is based on measurable SOM fractions is that its internal structure and dynamics can be directly calibrated and validated by using experimental data. In conclusion, AggModel successfully incorporates the explicit representation for the turnover of soil aggregates and their influence on SOM dynamics and can form the basis for new SOM modules within existing ecosystem models.« less

Thermodynamic Modeling of Organic-Inorganic Aerosols with the Group-Contribution Model AIOMFAC

NASA Astrophysics Data System (ADS)

Zuend, A.; Marcolli, C.; Luo, B. P.; Peter, T.

2009-04-01

Liquid aerosol particles are - from a physicochemical viewpoint - mixtures of inorganic salts, acids, water and a large variety of organic compounds (Rogge et al., 1993; Zhang et al., 2007). Molecular interactions between these aerosol components lead to deviations from ideal thermodynamic behavior. Strong non-ideality between organics and dissolved ions may influence the aerosol phases at equilibrium by means of liquid-liquid phase separations into a mainly polar (aqueous) and a less polar (organic) phase. A number of activity models exists to successfully describe the thermodynamic equilibrium of aqueous electrolyte solutions. However, the large number of different, often multi-functional, organic compounds in mixed organic-inorganic particles is a challenging problem for the development of thermodynamic models. The group-contribution concept as introduced in the UNIFAC model by Fredenslund et al. (1975), is a practical method to handle this difficulty and to add a certain predictability for unknown organic substances. We present the group-contribution model AIOMFAC (Aerosol Inorganic-Organic Mixtures Functional groups Activity Coefficients), which explicitly accounts for molecular interactions between solution constituents, both organic and inorganic, to calculate activities, chemical potentials and the total Gibbs energy of mixed systems (Zuend et al., 2008). This model enables the computation of vapor-liquid (VLE), liquid-liquid (LLE) and solid-liquid (SLE) equilibria within one framework. Focusing on atmospheric applications we considered eight different cations, five anions and a wide range of alcohols/polyols as organic compounds. With AIOMFAC, the activities of the components within an aqueous electrolyte solution are very well represented up to high ionic strength. We show that the semi-empirical middle-range parametrization of direct organic-inorganic interactions in alcohol-water-salt solutions enables accurate computations of vapor-liquid and liquid-liquid equilibria. References Fredenslund, A., Jones, R. L., and Prausnitz, J. M.: Group-Contribution Estimation of Activity Coefficients in Nonideal Liquid Mixtures, AIChE J., 21, 1086-1099, 1975. Rogge, W. F., Mazurek, M. A., Hildemann, L. M., Cass, G. R., and Simoneit, B. R. T.: Quantification of Urban Organic Aerosols at a Molecular Level: Identification, Abundance and Seasonal Variation, Atmos. Environ., 27, 1309-1330, 1993. Zhang, Q. et al.: Ubiquity and dominance of oxygenated species in organic aerosols in anthropogenically influenced Northern Hemisphere midlatitudes, Geophys. Res. Lett., 34, L13 801, 2007. Zuend, A., Marcolli, C., Luo, B. P., and Peter, T.: A thermodynamic model of mixed organic-inorganic aerosols to predict activity coefficients, Atmos. Chem. Phys., 8, 4559-4593, 2008.

Organ-on-a-Chip Systems: Microengineering to Biomimic Living Systems.

PubMed

Zheng, Fuyin; Fu, Fanfan; Cheng, Yao; Wang, Chunyan; Zhao, Yuanjin; Gu, Zhongze

2016-05-01

"Organ-on-a-chip" systems integrate microengineering, microfluidic technologies, and biomimetic principles to create key aspects of living organs faithfully, including critical microarchitecture, spatiotemporal cell-cell interactions, and extracellular microenvironments. This creative platform and its multiorgan integration recapitulating organ-level structures and functions can bring unprecedented benefits to a diversity of applications, such as developing human in vitro models for healthy or diseased organs, enabling the investigation of fundamental mechanisms in disease etiology and organogenesis, benefiting drug development in toxicity screening and target discovery, and potentially serving as replacements for animal testing. Recent advances in novel designs and examples for developing organ-on-a-chip platforms are reviewed. The potential for using this emerging technology in understanding human physiology including mechanical, chemical, and electrical signals with precise spatiotemporal controls are discussed. The current challenges and future directions that need to be pursued for these proof-of-concept studies are also be highlighted. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Reflections on experiential learning in evaluation capacity building with a community organization, Dancing With Parkinson's.

PubMed

Nakaima, April; Sridharan, Sanjeev

2017-05-08

This paper discusses what was learned about evaluation capacity building with community organizations who deliver services to individuals with neurological disorders. Evaluation specialists engaged by the Ontario Brain Institute Evaluation Support Program were paired with community organizations, such as Dancing With Parkinson's. Some of the learning included: relationship building is key for this model of capacity building; community organizations often have had negative experiences with evaluation and the idea that evaluations can be friendly tools in implementing meaningful programs is one key mechanism by which such an initiative can work; community organizations often need evaluation most to be able to demonstrate their value; a strength of this initiative was that the focus was not just on creating products but mostly on developing a learning process in which capacities would remain; evaluation tools and skills that organizations found useful were developing a theory of change and the concept of heterogeneous mechanisms (informed by a realist evaluation lens). Copyright © 2017. Published by Elsevier Ltd.

Factors which influence Texas biology teachers' decisions to emphasize fundamental concepts of evolution

NASA Astrophysics Data System (ADS)

Bilica, Kimberly Lynn

The teaching of biological evolution in public science classrooms has been mitigated by a lingering and historic climate of controversy (Skoog, 1984; Skoog, 1979). This controversy has successfully stalled attempts to bring authentic science literacy to the American public (Bybee, 1997). The first encouraging signs of the abatement of this controversy occurred during the early 1990s when several prominent science organizations promoted evolution to its appropriate status as a central and unifying concept in biology (National Science Teachers Association, 1992; National Research Council, 1996; American Association for the Advancement of Science, 1990, 1993). The organizations acknowledged that not only should biological evolution be taught, evolution should stand as one of a select group of essential concepts upon which biology curricula should be built. Bandura's Social Learning theory (Bandura, 1997; Lumpe, Haney, & Czerniak, 2000) and Helms' Model of Identity (Helms, 1998) provide the theoretical basis for this study. Both Bandura and Helms explain the actions of teachers by examining the beliefs and values that influence their decisions. The models distinguish between two types of belief systems: capacity beliefs and context beliefs (Lumpe, et al, 2000; Helms, 1998). Both belief types influence and are influenced by individual actions. In this study, the action to be described is the decision that teachers make about the degree of emphasis on evolution in the classroom. The capacity beliefs that will be examined are teachers' beliefs about their capability to teach evolution. The contextual beliefs in this study are perceptions about students' capabilities to learn evolution, the status of evolution in science, the place of evolution in the biology classroom, the influence of textbooks, time, and community/school values. This study contributes to and extends the knowledge base established by studies of evolution education by exploring the relative amount of emphasis that Texas biology teachers currently as well as prefer to place on fundamental evolution concepts in relationship to specific belief factors which influence biology teachers' curricular decisions.

D'Arcy Thompson's 'on Growth and form': From soap bubbles to tissue self-organization.

PubMed

Heisenberg, Carl-Philipp

2017-06-01

Tissues are thought to behave like fluids with a given surface tension. Differences in tissue surface tension (TST) have been proposed to trigger cell sorting and tissue envelopment. D'Arcy Thompson in his seminal book 'On Growth and Form' has introduced this concept of differential TST as a key physical mechanism dictating tissue formation and organization within the developing organism. Over the past century, many studies have picked up the concept of differential TST and analyzed the role and cell biological basis of TST in development, underlining the importance and influence of this concept in developmental biology. Copyright © 2017 Elsevier B.V. All rights reserved.

An effective self-assessment based on concept map extraction from test-sheet for personalized learning

NASA Astrophysics Data System (ADS)

Liew, Keng-Hou; Lin, Yu-Shih; Chang, Yi-Chun; Chu, Chih-Ping

2013-12-01

Examination is a traditional way to assess learners' learning status, progress and performance after a learning activity. Except the test grade, a test sheet hides some implicit information such as test concepts, their relationships, importance, and prerequisite. The implicit information can be extracted and constructed a concept map for considering (1) the test concepts covered in the same question means these test concepts have strong relationships, and (2) questions in the same test sheet means the test concepts are relative. Concept map has been successfully employed in many researches to help instructors and learners organize relationships among concepts. However, concept map construction depends on experts who need to take effort and time for the organization of the domain knowledge. In addition, the previous researches regarding to automatic concept map construction are limited to consider all learners of a class, which have not considered personalized learning. To cope with this problem, this paper proposes a new approach to automatically extract and construct concept map based on implicit information in a test sheet. Furthermore, the proposed approach also can help learner for self-assessment and self-diagnosis. Finally, an example is given to depict the effectiveness of proposed approach.

[The contribution of systems theory and "existential integrative psychotherapy" to the relationship of the concepts "endogenous", "exogenous", "psychogenic", and "sociogenic" in psychic disorders].

PubMed

Bühler, K E; Wyss, D

1980-01-01

Proof is given that the "atomistic" concepts of sickness lead to insolvable contradictions of methodic and logic origin. In this study these contradictions are exemplified and critically analysed, and historical aspects are included. We then propose the dimensions "Interior--Exterior" and "Psychogenous--Somatogeneous" as an heuristic model, dimensions on which any sickness is to be located according to its basic causes. The General System Theory had developed a new formal concept of sickness based on a relatively complete and integral vision of the human being. Nevertheless, the constructs of the General System Theory remain incomplete as they include only objects and their relations, never individual subjects. Wyss however has established explicitely an anthropology of the subject which he connects with his communication orientated concept of sickness. This concept does not judge sickness to be contradictory to health, but both, sickness and health together, form a functional whole on a higher level of abstraction. On this level the organism and its functions, the "interior", represent an inherent component of the "exterior". "Interior" and "exterior"--differentiated in various items--attempt to establish an equilibrium that is always in danger of being desquilibrized.

Progress toward a general species concept.

PubMed

Hausdorf, Bernhard

2011-04-01

New insights in the speciation process and the nature of "species" that accumulated in the past decade demand adjustments of the species concept. The standing of some of the most broadly accepted or most innovative species concepts in the light of the growing evidence that reproductive barriers are semipermeable to gene flow, that species can differentiate despite ongoing interbreeding, that a single species can originate polyphyletically by parallel evolution, and that uniparental organisms are organised in units that resemble species of biparental organisms is discussed. As a synthesis of ideas in existing concepts and the new insights, a generalization of the genic concept is proposed that defines species as groups of individuals that are reciprocally characterized by features that would have negative fitness effects in other groups and that cannot be regularly exchanged between groups upon contact. The benefits of this differential fitness species concept are that it classifies groups that keep differentiated and keep on differentiating despite interbreeding as species, that it is not restricted to specific mutations or mechanisms causing speciation, and that it can be applied to the whole spectrum of organisms from uni- to biparentals. © 2011 The Author(s). Evolution© 2011 The Society for the Study of Evolution.

Variables contributing to an excellent customer service management profile within the regulated electric utility industry: A comparison of self-concept with customer satisfaction for customer service management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, L.E.

1991-01-01

This research sought to address the relationship between self-concept and customer satisfaction: can customer satisfaction with a major electric utility be explained in terms of the self-reported, self-concept of the utility's managers The population to which the results of this study were generalized consisted of customer service managers in public electric utilities across the United States. In order to represent this population, a sample was selected consisting of customer service managers at a midwestern electric utility based in a large metropolitan area. Participants in this study were managers of four direct customer contact service organizations within six geographic division organizations.more » The methodology included comparisons of these four customer contact service organizations on twelve independent, self-concept variables and six customer satisfaction dependent variables using Analysis of Variance (ANOVA), Scheffe' tests, Chi-Square, and Stepwise multiple regression. The groups were found not to be significantly different and knowledge of the self-concept scores for managers will not increase the ability to predict customer satisfaction over no knowledge of self-concept scores.« less

μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips.

PubMed

Loskill, Peter; Marcus, Sivan G; Mathur, Anurag; Reese, Willie Mae; Healy, Kevin E

2015-01-01

Human organ-on-a-chip systems for drug screening have evolved as feasible alternatives to animal models, which are unreliable, expensive, and at times erroneous. While chips featuring single organs can be of great use for both pharmaceutical testing and basic organ-level studies, the huge potential of the organ-on-a-chip technology is revealed by connecting multiple organs on one chip to create a single integrated system for sophisticated fundamental biological studies and devising therapies for disease. Furthermore, since most organ-on-a-chip systems require special protocols with organ-specific media for the differentiation and maturation of the tissues, multi-organ systems will need to be temporally customizable and flexible in terms of the time point of connection of the individual organ units. We present a customizable Lego®-like plug & play system, μOrgano, which enables initial individual culture of single organ-on-a-chip systems and subsequent connection to create integrated multi-organ microphysiological systems. As a proof of concept, the μOrgano system was used to connect multiple heart chips in series with excellent cell viability and spontaneously physiological beat rates.

μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips

PubMed Central

Loskill, Peter; Marcus, Sivan G.; Mathur, Anurag; Reese, Willie Mae; Healy, Kevin E.

2015-01-01

Human organ-on-a-chip systems for drug screening have evolved as feasible alternatives to animal models, which are unreliable, expensive, and at times erroneous. While chips featuring single organs can be of great use for both pharmaceutical testing and basic organ-level studies, the huge potential of the organ-on-a-chip technology is revealed by connecting multiple organs on one chip to create a single integrated system for sophisticated fundamental biological studies and devising therapies for disease. Furthermore, since most organ-on-a-chip systems require special protocols with organ-specific media for the differentiation and maturation of the tissues, multi-organ systems will need to be temporally customizable and flexible in terms of the time point of connection of the individual organ units. We present a customizable Lego®-like plug & play system, μOrgano, which enables initial individual culture of single organ-on-a-chip systems and subsequent connection to create integrated multi-organ microphysiological systems. As a proof of concept, the μOrgano system was used to connect multiple heart chips in series with excellent cell viability and spontaneously physiological beat rates. PMID:26440672

Computing organic stereoselectivity - from concepts to quantitative calculations and predictions.

PubMed

Peng, Qian; Duarte, Fernanda; Paton, Robert S

2016-11-07

Advances in theory and processing power have established computation as a valuable interpretative and predictive tool in the discovery of new asymmetric catalysts. This tutorial review outlines the theory and practice of modeling stereoselective reactions. Recent examples illustrate how an understanding of the fundamental principles and the application of state-of-the-art computational methods may be used to gain mechanistic insight into organic and organometallic reactions. We highlight the emerging potential of this computational tool-box in providing meaningful predictions for the rational design of asymmetric catalysts. We present an accessible account of the field to encourage future synergy between computation and experiment.

Promoting collective recovery through organizational mobilization: the post-9/11 disaster relief work of NYC RECOVERS.

PubMed

Fullilove, Mindy Thompson; Hernandez-Cordero, Lourdes; Madoff, Jennifer Stevens; Fullilove, Robert E

2004-07-01

NYC RECOVERS, an alliance of organizations concerned with New York City's social and emotional recovery post-9/11, was formed to meet the need to rebuild social bonds strained or ruptured by the trauma to the regional system caused by the destruction of the Twin Towers. NYC RECOVERS, with minimal funding, was able to create a network of 1000 organizations spanning the five boroughs, carrying out recovery events throughout the 'Year of Recovery', September 2001 to December 2002. This paper describes the concepts, techniques and accomplishments of NYC RECOVERS, and discusses potentials of the model, as well as obstacles to its implementation.

Mathematical modelling of the influenced of diffusion rate on macro nutrient availability in paddy field

NASA Astrophysics Data System (ADS)

Renny; Supriyanto

2018-04-01

Nutrition is the chemical compounds that needed by the organism for the growth process. In plants, nutrients are organic or inorganic compounds that are absorbed from the roots of the soil. It consist of macro and micro nutrient. Macro nutrients are nutrition that needed by plants in large quantities, such as, nitrogen, calcium, pottacium, magnesium, and sulfur. The total soil nutrient is the difference between the input nutrient and the output nutrients. Input nutrients are nutrient that derived from the decomposition of organic substances. Meanwhile, the output nutrient consists of the nutrients that absorbed by plant roots (uptake), the evaporated nutrients (volatilized) and leached nutrients. The nutrient transport can be done through diffusion process. The diffusion process is essential in removing the nutrient from one place to the root surface. It will cause the rate of absorption of nutrient by the roots will be greater. Nutrient concept in paddy filed can be represented into a mathematical modelling, by making compartment models. The rate of concentration change in the compartment model forms a system of homogeneous linear differential equations. In this research, we will use Laplaces transformation to solve the compartment model and determined the dynamics of macro nutrition due to diffusion process.

Predicting chromatin architecture from models of polymer physics.

PubMed

Bianco, Simona; Chiariello, Andrea M; Annunziatella, Carlo; Esposito, Andrea; Nicodemi, Mario

2017-03-01

We review the picture of chromatin large-scale 3D organization emerging from the analysis of Hi-C data and polymer modeling. In higher mammals, Hi-C contact maps reveal a complex higher-order organization, extending from the sub-Mb to chromosomal scales, hierarchically folded in a structure of domains-within-domains (metaTADs). The domain folding hierarchy is partially conserved throughout differentiation, and deeply correlated to epigenomic features. Rearrangements in the metaTAD topology relate to gene expression modifications: in particular, in neuronal differentiation models, topologically associated domains (TADs) tend to have coherent expression changes within architecturally conserved metaTAD niches. To identify the nature of architectural domains and their molecular determinants within a principled approach, we discuss models based on polymer physics. We show that basic concepts of interacting polymer physics explain chromatin spatial organization across chromosomal scales and cell types. The 3D structure of genomic loci can be derived with high accuracy and its molecular determinants identified by crossing information with epigenomic databases. In particular, we illustrate the case of the Sox9 locus, linked to human congenital disorders. The model in-silico predictions on the effects of genomic rearrangements are confirmed by available 5C data. That can help establishing new diagnostic tools for diseases linked to chromatin mis-folding, such as congenital disorders and cancer.

Impact of organ shape variations on margin concepts for cervix cancer ART.

PubMed

Seppenwoolde, Yvette; Stock, Markus; Buschmann, Martin; Georg, Dietmar; Bauer-Novotny, Kwei-Yuang; Pötter, Richard; Georg, Petra

2016-09-01

Target and organ movement motivate adaptive radiotherapy for cervix cancer patients. We investigated the dosimetric impact of margin concepts with different levels of complexity on both organ at risk (OAR) sparing and PTV coverage. Weekly CT and daily CBCT scans were delineated for 10 patients. The dosimetric impact of organ shape variations were evaluated for four (isotropic) margin concepts: two static PTVs (PTV 6mm and PTV 15mm ), a PTV based on ITV of the planning CT and CBCTs of the first treatment week (PTV ART ITV ) and an adaptive PTV based on a library approach (PTV ART Library ). Using static concepts, OAR doses increased with large margins, while smaller margins compromised target coverage. ART PTVs resulted in comparable target coverage and better sparing of bladder (V40Gy: 15% and 7% less), rectum (V40Gy: 18 and 6cc less) and bowel (V40Gy: 106 and 15cc less) compared to PTV 15mm . Target coverage evaluation showed that for elective fields a static 5mm margin sufficed. PTV ART Library achieved the best dosimetric results. However when weighing clinical benefit against workload, ITV margins based on repetitive movement evaluation during the first week also provide improvements over static margin concepts. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Learning and Knowledge: A Dream or Nightmare for Employees

ERIC Educational Resources Information Center

Newman, Nadine; Newman, Dunstan

2015-01-01

Purpose: The paper aims to focus on the issues relating to the concepts of knowledge management (KM) and the learning organization and discusses the relationship between these concepts and the issues of power and control. It looks at Coopey's (1998) critical review of the "Foucauldian gloom" with regard to the learning organization and…

How the Concept of Organizational Unlearning Contributes to Studies of Learning Organizations: A Personal Reflection

ERIC Educational Resources Information Center

Tsang, Eric W. K.

2017-01-01

Purpose: The first purpose of this short essay is to respond to Howells and Scholderer's (2016) harsh critique that organizational unlearning is a superfluous concept. The second purpose is to establish a relationship between organizational unlearning and the learning organization. Design/methodology/approach: To respond to Howells and…

Sport and Social Organization.

ERIC Educational Resources Information Center

Nixon, Howard L., II

Sport is examined in relation to a number of basic aspects of social organization. Each of the seven sections includes a brief clarification of the key sociological concepts used for analysis, a consideration of various applications of those concepts to sport, and a review and discussion of what is known about specific aspects of sport in relation…

Organic geochemistry of core samples from an ultradeep hot well (300°C, 7 km)

USGS Publications Warehouse

Price, Leigh C.

1982-01-01

Concepts prevelant among petroleum organic geochemists concerning the thermal fate of hydrocarbons, with subsequent graphite formation, and greenschist metamorphism, are in sharp contradiction to these data. Conventional concepts of the distribution of heavy hydrocarbons with increasing temperature and depth apparently require further review and revision.

Planning in Reverse: A Viable Approach to Organizational Leadership

ERIC Educational Resources Information Center

Ballantyne, Scott; Berret, Beth; Wells, Mary Ellen

2011-01-01

Planning in Reverse is an innovative concept designed to make organizations more successful by altering the perspective utilized in the strategy process. What is needed for organizations to thrive in this new environment of change and uncertainty is a short-term approach for long-term viability. In this book, tools and concepts regarding Planning…

Assessment of Development of the Learning Organization Concept in Jordanian Industrial Companies

ERIC Educational Resources Information Center

Khadra, Marah F. Abu; Rawabdeh, Ibrahim A.

2006-01-01

Purpose: The purpose of this research is to examine the impact on organizational performance of the application of management and human resource practices, and to attempt to outline key elements and assess development of the learning organization (LO) concept in Jordan. Design/methodology/approach: The tool described in this article assesses…

Narrative Constructions for the Organization of Self Experience: Proof of Concept via Embodied Robotics.

PubMed

Mealier, Anne-Laure; Pointeau, Gregoire; Mirliaz, Solène; Ogawa, Kenji; Finlayson, Mark; Dominey, Peter F

2017-01-01

It has been proposed that starting from meaning that the child derives directly from shared experience with others, adult narrative enriches this meaning and its structure, providing causal links between unseen intentional states and actions. This would require a means for representing meaning from experience-a situation model-and a mechanism that allows information to be extracted from sentences and mapped onto the situation model that has been derived from experience, thus enriching that representation. We present a hypothesis and theory concerning how the language processing infrastructure for grammatical constructions can naturally be extended to narrative constructions to provide a mechanism for using language to enrich meaning derived from physical experience. Toward this aim, the grammatical construction models are augmented with additional structures for representing relations between events across sentences. Simulation results demonstrate proof of concept for how the narrative construction model supports multiple successive levels of meaning creation which allows the system to learn about the intentionality of mental states, and argument substitution which allows extensions to metaphorical language and analogical problem solving. Cross-linguistic validity of the system is demonstrated in Japanese. The narrative construction model is then integrated into the cognitive system of a humanoid robot that provides the memory systems and world-interaction required for representing meaning in a situation model. In this context proof of concept is demonstrated for how the system enriches meaning in the situation model that has been directly derived from experience. In terms of links to empirical data, the model predicts strong usage based effects: that is, that the narrative constructions used by children will be highly correlated with those that they experience. It also relies on the notion of narrative or discourse function words. Both of these are validated in the experimental literature.

[Survival strategy of photosynthetic organisms. 1. Variability of the extent of light-harvesting pigment aggregation as a structural factor optimizing the function of oligomeric photosynthetic antenna. Model calculations].

PubMed

Fetisova, Z G

2004-01-01

In accordance with our concept of rigorous optimization of photosynthetic machinery by a functional criterion, this series of papers continues purposeful search in natural photosynthetic units (PSU) for the basic principles of their organization that we predicted theoretically for optimal model light-harvesting systems. This approach allowed us to determine the basic principles for the organization of a PSU of any fixed size. This series of papers deals with the problem of structural optimization of light-harvesting antenna of variable size controlled in vivo by the light intensity during the growth of organisms, which accentuates the problem of antenna structure optimization because optimization requirements become more stringent as the PSU increases in size. In this work, using mathematical modeling for the functioning of natural PSUs, we have shown that the aggregation of pigments of model light-harvesting antenna, being one of universal optimizing factors, furthermore allows controlling the antenna efficiency if the extent of pigment aggregation is a variable parameter. In this case, the efficiency of antenna increases with the size of the elementary antenna aggregate, thus ensuring the high efficiency of the PSU irrespective of its size; i.e., variation in the extent of pigment aggregation controlled by the size of light-harvesting antenna is biologically expedient.

Bio-soliton model that predicts non-thermal electromagnetic frequency bands, that either stabilize or destabilize living cells.

PubMed

Geesink, J H; Meijer, D K F

2017-01-01

Solitons, as self-reinforcing solitary waves, interact with complex biological phenomena such as cellular self-organization. A soliton model is able to describe a spectrum of electromagnetism modalities that can be applied to understand the physical principles of biological effects in living cells, as caused by endogenous and exogenous electromagnetic fields and is compatible with quantum coherence. A bio-soliton model is proposed, that enables to predict which eigen-frequencies of non-thermal electromagnetic waves are life-sustaining and which are, in contrast, detrimental for living cells. The particular effects are exerted by a range of electromagnetic wave eigen-frequencies of one-tenth of a Hertz till Peta Hertz that show a pattern of 12 bands, and can be positioned on an acoustic reference frequency scale. The model was substantiated by a meta-analysis of 240 published articles of biological electromagnetic experiments, in which a spectrum of non-thermal electromagnetic waves were exposed to living cells and intact organisms. These data support the concept of coherent quantized electromagnetic states in living organisms and the theories of Fröhlich, Davydov and Pang. It is envisioned that a rational control of shape by soliton-waves and related to a morphogenetic field and parametric resonance provides positional information and cues to regulate organism-wide systems properties like anatomy, control of reproduction and repair.

A Quantitative Empirical Analysis of the Abstract/Concrete Distinction

ERIC Educational Resources Information Center

Hill, Felix; Korhonen, Anna; Bentz, Christian

2014-01-01

This study presents original evidence that abstract and concrete concepts are organized and represented differently in the mind, based on analyses of thousands of concepts in publicly available data sets and computational resources. First, we show that abstract and concrete concepts have differing patterns of association with other concepts.…

Evidence-Based Concept Mapping for the Athletic Training Student

ERIC Educational Resources Information Center

Speicher, Timothy E.; Martin, Malissa; Zigmont, Jason

2013-01-01

Context: A concept map is a graphical and cognitive tool that enables learners to link together interrelated concepts using propositions or statements that answer a posed problem. As an assessment tool, concept mapping reveals a learner's research skill proficiency and cognitive processing. Background: The identification and organization of the…

Estimation of design space for an extrusion-spheronization process using response surface methodology and artificial neural network modelling.

PubMed

Sovány, Tamás; Tislér, Zsófia; Kristó, Katalin; Kelemen, András; Regdon, Géza

2016-09-01

The application of the Quality by Design principles is one of the key issues of the recent pharmaceutical developments. In the past decade a lot of knowledge was collected about the practical realization of the concept, but there are still a lot of unanswered questions. The key requirement of the concept is the mathematical description of the effect of the critical factors and their interactions on the critical quality attributes (CQAs) of the product. The process design space (PDS) is usually determined by the use of design of experiment (DoE) based response surface methodologies (RSM), but inaccuracies in the applied polynomial models often resulted in the over/underestimation of the real trends and changes making the calculations uncertain, especially in the edge regions of the PDS. The completion of RSM with artificial neural network (ANN) based models is therefore a commonly used method to reduce the uncertainties. Nevertheless, since the different researches are focusing on the use of a given DoE, there is lack of comparative studies on different experimental layouts. Therefore, the aim of present study was to investigate the effect of the different DoE layouts (2 level full factorial, Central Composite, Box-Behnken, 3 level fractional and 3 level full factorial design) on the model predictability and to compare model sensitivities according to the organization of the experimental data set. It was revealed that the size of the design space could differ more than 40% calculated with different polynomial models, which was associated with a considerable shift in its position when higher level layouts were applied. The shift was more considerable when the calculation was based on RSM. The model predictability was also better with ANN based models. Nevertheless, both modelling methods exhibit considerable sensitivity to the organization of the experimental data set, and the use of design layouts is recommended, where the extreme values factors are more represented. Copyright © 2016 Elsevier B.V. All rights reserved.

Trickling filter for urea and bio-waste processing - dynamic modelling of nitrogen cycle

NASA Astrophysics Data System (ADS)

Zhukov, Anton; Hauslage, Jens; Tertilt, Gerin; Bornemann, Gerhild

Mankind’s exploration of the solar system requires reliable Life Support Systems (LSS) enabling long duration manned space missions. In the absence of frequent resupply missions, closure of the LSS will play a very important role and its maximisation will to a large extent drive the selection of appropriate LSS architectures. One of the significant issues on the way to full closure is to effectively utilise biological wastes such as urine, inedible biomass etc. A very promising concept of biological waste reprocessing is the use of trickling filters which are currently being developed and investigated by DLR, Cologne, Germany. The concept is called Combined Regenerative Organic-Food Production (C.R.O.P.) and is based on the microbiological treatment of biological wastes and reprocessing them into aqueous fertilizer which can directly be used in a greenhouse for food production. Numerous experiments have been and are being conducted by DLR in order to fully understand and characterize the process. The human space exploration group of the Technical University of Munich (TUM) in cooperation with DLR has started to establish a dynamic model of the trickling filter system to be able to assess its performance on the LSS level. In the first development stage the model covers the nitrogen cycle enabling to simulate urine processing. This paper describes briefly the C.R.O.P. concept and the status of the trickling filter model development. The model is based on enzyme-catalyzed reaction kinetics for the fundamental microbiological reaction chain and is created in MATLAB. Verification and correlation of the developed model with experiment results has been performed. Several predictive studies for batch sequencing behavior have been performed, demonstrating a good capability of C.R.O.P. concept to be used in closed LSS. Achieved results are critically discussed and way forward is presented.

PGSB/MIPS Plant Genome Information Resources and Concepts for the Analysis of Complex Grass Genomes.

PubMed

Spannagl, Manuel; Bader, Kai; Pfeifer, Matthias; Nussbaumer, Thomas; Mayer, Klaus F X

2016-01-01

PGSB (Plant Genome and Systems Biology; formerly MIPS-Munich Institute for Protein Sequences) has been involved in developing, implementing and maintaining plant genome databases for more than a decade. Genome databases and analysis resources have focused on individual genomes and aim to provide flexible and maintainable datasets for model plant genomes as a backbone against which experimental data, e.g., from high-throughput functional genomics, can be organized and analyzed. In addition, genomes from both model and crop plants form a scaffold for comparative genomics, assisted by specialized tools such as the CrowsNest viewer to explore conserved gene order (synteny) between related species on macro- and micro-levels.The genomes of many economically important Triticeae plants such as wheat, barley, and rye present a great challenge for sequence assembly and bioinformatic analysis due to their enormous complexity and large genome size. Novel concepts and strategies have been developed to deal with these difficulties and have been applied to the genomes of wheat, barley, rye, and other cereals. This includes the GenomeZipper concept, reference-guided exome assembly, and "chromosome genomics" based on flow cytometry sorted chromosomes.

Expansive or limitative strategy? A case study of organisational responses to new public health.

PubMed

Nielsen, Annegrete Juul; Knudsen, Morten; Finke, Katrine

2008-01-01

Since the emergence of new public health in the 1970s, health has not merely been considered the absence of disease, but physical, mental and social wellbeing. This article seeks to analyzes the implications of this broad concept of health at an organizational level. The paper presents a qualitative case study of boundary drawing in a Danish municipal agency in charge of planning and conducting health promoting and disease preventing activities from 1989 to 2005. The theoretical framework draws on Niklas Luhmann's organization theory. Two different organizational answers were found to the challenges inherent in the broad concept of new public health. First, the organization tried to increase its size and incorporate as many aspects of the environment as possible. This expansive strategy jeopardised the identity of the organization. Second, the organization tried to keep clear and tight boundaries and from this position irritate entities in the environment. This limitative strategy made the organization spend relatively more energy on organizing and controlling itself than on public health work. The case study shows how a broad concept of health makes boundary management topical in organizations dealing with health promotion and disease prevention. Organizations in charge of public health activities need to reflect on how they can create intelligent compensations for the disadvantages involved in an expansive or a limitative strategy. The broad concept of health inherent in new public health has been widely accepted and yet its challenges to organizational boundary drawing have attracted little attention. This paper provides an analysis of these challenges.

Supervised self-organization of homogeneous swarms using ergodic projections of Markov chains.

PubMed

Chattopadhyay, Ishanu; Ray, Asok

2009-12-01

This paper formulates a self-organization algorithm to address the problem of global behavior supervision in engineered swarms of arbitrarily large population sizes. The swarms considered in this paper are assumed to be homogeneous collections of independent identical finite-state agents, each of which is modeled by an irreducible finite Markov chain. The proposed algorithm computes the necessary perturbations in the local agents' behavior, which guarantees convergence to the desired observed state of the swarm. The ergodicity property of the swarm, which is induced as a result of the irreducibility of the agent models, implies that while the local behavior of the agents converges to the desired behavior only in the time average, the overall swarm behavior converges to the specification and stays there at all times. A simulation example illustrates the underlying concept.

Identity impairment and the eating disorders: content and organization of the self-concept in women with anorexia nervosa and bulimia nervosa.

PubMed

Stein, Karen Farchaus; Corte, Colleen

2007-01-01

The cognitive model of the self-concept was used to test the theoretical proposition that disturbances in overall identity development are a core vulnerability that lead to formation of a fat body weight self-definition and eating disorder symptomatology. Structural properties of the self-concept, availability in memory of a fat body weight self-schema, and eating disordered attitudes and behaviours were measured in women with anorexia nervosa (AN) (n = 26), bulimia nervosa (BN) (n = 53) and controls (n = 32). Women with (AN) and (BN) had fewer positive and more negative and highly interrelated self-schemas compared to controls, and women with BN showed information processing evidence of a fat self-schema available in memory. These self-concept properties predicted eating disordered attitudes and behaviour. Disturbances in the overall collection of identities--an impoverished self--is an important contributor to eating disorder symptomatology. The development of new positive selves may be an important factor in recovery. 2006 John Wiley & Sons, Ltd and Eating Disorders Association

On theoretical and experimental modeling of metabolism forming in prebiotic systems

NASA Astrophysics Data System (ADS)

Bartsev, S. I.; Mezhevikin, V. V.

Recently searching for extraterrestrial life attracts more and more attention However the searching hardly can be effective without sufficiently universal concept of life origin which incidentally tackles a problem of origin of life on the Earth A concept of initial stages of life origin including origin of prebiotic metabolism is stated in the paper Suggested concept eliminates key difficulties in the problem of life origin and allows experimental verification of it According to the concept the predecessor of living beings has to be sufficiently simple to provide non-zero probability of self-assembling during short in geological or cosmic scale time In addition the predecessor has to be capable of autocatalysis and further complication evolution A possible scenario of initial stage of life origin which can be realized both on other planets and inside experimental facility is considered In the scope of the scenario a theoretical model of multivariate oligomeric autocatalyst coupled with phase-separated particle is presented Results of computer simulation of possible initial stage of chemical evolution are shown Conducted estimations show the origin of autocatalytic oligomeric phase-separated system is possible at reasonable values of kinetic parameters of involved chemical reactions in a small-scale flow reactor Accepted statements allowing to eliminate key problems of life origin imply important consequence -- organisms emerged out of the Earth or inside a reactor have to be based on another different from terrestrial biochemical

Terminology for Neuroscience Data Discovery: Multi-tree Syntax and Investigator-Derived Semantics

PubMed Central

Goldberg, David H.; Grafstein, Bernice; Robert, Adrian; Gardner, Esther P.

2009-01-01

The Neuroscience Information Framework (NIF), developed for the NIH Blueprint for Neuroscience Research and available at http://nif.nih.gov and http://neurogateway.org, is built upon a set of coordinated terminology components enabling data and web-resource description and selection. Core NIF terminologies use a straightforward syntax designed for ease of use and for navigation by familiar web interfaces, and readily exportable to aid development of relational-model databases for neuroscience data sharing. Datasets, data analysis tools, web resources, and other entities are characterized by multiple descriptors, each addressing core concepts, including data type, acquisition technique, neuroanatomy, and cell class. Terms for each concept are organized in a tree structure, providing is-a and has-a relations. Broad general terms near each root span the category or concept and spawn more detailed entries for specificity. Related but distinct concepts (e.g., brain area and depth) are specified by separate trees, for easier navigation than would be required by graph representation. Semantics enabling NIF data discovery were selected at one or more workshops by investigators expert in particular systems (vision, olfaction, behavioral neuroscience, neurodevelopment), brain areas (cerebellum, thalamus, hippocampus), preparations (molluscs, fly), diseases (neurodegenerative disease), or techniques (microscopy, computation and modeling, neurogenetics). Workshop-derived integrated term lists are available Open Source at http://brainml.org; a complete list of participants is at http://brainml.org/workshops. PMID:18958630

A reference architecture for the component factory

NASA Technical Reports Server (NTRS)

Basili, Victor R.; Caldiera, Gianluigi; Cantone, Giovanni

1992-01-01

Software reuse can be achieved through an organization that focuses on utilization of life cycle products from previous developments. The component factory is both an example of the more general concepts of experience and domain factory and an organizational unit worth being considered independently. The critical features of such an organization are flexibility and continuous improvement. In order to achieve these features we can represent the architecture of the factory at different levels of abstraction and define a reference architecture from which specific architectures can be derived by instantiation. A reference architecture is an implementation and organization independent representation of the component factory and its environment. The paper outlines this reference architecture, discusses the instantiation process, and presents some examples of specific architectures by comparing them in the framework of the reference model.

Household Energy Consumption: Community Context and the Fuelwood Transition*

PubMed Central

Link, Cynthia F.; Axinn, William G.; Ghimire, Dirgha J.

2012-01-01

We examine the influence of community context on change over time in households’ use of non-wood fuels. Our theoretical framework builds on sociological concepts in order to study energy consumption at the micro-level. The framework emphasizes the importance of nonfamily organizations and services in the local community as determinants of the transition from use of fuelwood to use of alternative fuels. We use multilevel longitudinal data on household fuel choice and community context from rural Nepal to provide empirical tests of our theoretical model. Results reveal that increased exposure to nonfamily organizations in the local community increases the use of alternative fuels. The findings illustrate key features of human impacts on the local environment and motivate greater incorporation of social organization into research on environmental change. PMID:23017795

Analysis misconception of integers in microteaching activities

NASA Astrophysics Data System (ADS)

Setyawati, R. D.; Indiati, I.

2018-05-01

This study view to analyse student misconceptions on integers in microteaching activities. This research used qualitative research design. An integers test contained questions from eight main areas of integers. The Integers material test includes (a) converting the image into fractions, (b) examples of positive numbers including rational numbers, (c) operations in fractions, (d) sorting fractions from the largest to the smallest, and vice versa; e) equate denominator, (f) concept of ratio mark, (g) definition of fraction, and (h) difference between fractions and parts. The results indicated an integers concepts: (1) the students have not been able to define concepts well based on the classification of facts in organized part; (2) The correlational concept: students have not been able to combine interrelated events in the form of general principles; and (3) theoretical concepts: students have not been able to use concepts that facilitate in learning the facts or events in an organized system.

The Significance of an Enhanced Concept of the Organism for Medicine

PubMed Central

2016-01-01

Recent developments in evolutionary biology, comparative embryology, and systems biology suggest the necessity of a conceptual shift in the way we think about organisms. It is becoming increasingly evident that molecular and genetic processes are subject to extremely refined regulation and control by the cell and the organism, so that it becomes hard to define single molecular functions or certain genes as primary causes of specific processes. Rather, the molecular level is integrated into highly regulated networks within the respective systems. This has consequences for medical research in general, especially for the basic concept of personalized medicine or precision medicine. Here an integrative systems concept is proposed that describes the organism as a multilevel, highly flexible, adaptable, and, in this sense, autonomous basis for a human individual. The hypothesis is developed that these properties of the organism, gained from scientific observation, will gradually make it necessary to rethink the conceptual framework of physiology and pathophysiology in medicine. PMID:27446221

Topographic organization of the cerebral cortex and brain cartography.

PubMed

Eickhoff, Simon B; Constable, R Todd; Yeo, B T Thomas

2018-04-15

One of the most specific but also challenging properties of the brain is its topographic organization into distinct modules or cortical areas. In this paper, we first review the concept of topographic organization and its historical development. Next, we provide a critical discussion of the current definition of what constitutes a cortical area, why the concept has been so central to the field of neuroimaging and the challenges that arise from this view. A key aspect in this discussion is the issue of spatial scale and hierarchy in the brain. Focusing on in-vivo brain parcellation as a rapidly expanding field of research, we highlight potential limitations of the classical concept of cortical areas in the context of multi-modal parcellation and propose a revised interpretation of cortical areas building on the concept of neurobiological atoms that may be aggregated into larger units within and across modalities. We conclude by presenting an outlook on the implication of this revised concept for future mapping studies and raise some open questions in the context of brain parcellation. Copyright © 2017 Elsevier Inc. All rights reserved.

Testing the Nanoparticle-Allostatic Cross Adaptation-Sensitization Model for Homeopathic Remedy Effects

PubMed Central

Bell, Iris R.; Koithan, Mary; Brooks, Audrey J.

2012-01-01

Key concepts of the Nanoparticle-Allostatic Cross-Adaptation-Sensitization (NPCAS) Model for the action of homeopathic remedies in living systems include source nanoparticles as low level environmental stressors, heterotypic hormesis, cross-adaptation, allostasis (stress response network), time-dependent sensitization with endogenous amplification and bidirectional change, and self-organizing complex adaptive systems. The model accommodates the requirement for measurable physical agents in the remedy (source nanoparticles and/or source adsorbed to silica nanoparticles). Hormetic adaptive responses in the organism, triggered by nanoparticles; bipolar, metaplastic change, dependent on the history of the organism. Clinical matching of the patient’s symptom picture, including modalities, to the symptom pattern that the source material can cause (cross-adaptation and cross-sensitization). Evidence for nanoparticle-related quantum macro-entanglement in homeopathic pathogenetic trials. This paper examines research implications of the model, discussing the following hypotheses: Variability in nanoparticle size, morphology, and aggregation affects remedy properties and reproducibility of findings. Homeopathic remedies modulate adaptive allostatic responses, with multiple dynamic short- and long-term effects. Simillimum remedy nanoparticles, as novel mild stressors corresponding to the organism’s dysfunction initiate time-dependent cross-sensitization, reversing the direction of dysfunctional reactivity to environmental stressors. The NPCAS model suggests a way forward for systematic research on homeopathy. The central proposition is that homeopathic treatment is a form of nanomedicine acting by modulation of endogenous adaptation and metaplastic amplification processes in the organism to enhance long-term systemic resilience and health. PMID:23290882

Marketing for health-care organizations: an introduction to network management.

PubMed

Boonekamp, L C

1994-01-01

The introduction of regulated competition in health care in several Western countries confronts health care providing organizations with changing relationships, with their environment and a need for knowledge and skills to analyse and improve their market position. Marketing receives more and more attention, as recent developments in this field of study provide a specific perspective on the relationships between an organization and external and internal parties. In doing so, a basis is offered for network management. A problem is that the existing marketing literature is not entirely appropriate for the specific characteristics of health care. After a description of the developments in marketing and its most recent key concepts, the applicability of these concepts in health-care organizations is discussed. States that for the health-care sector, dominated by complex networks of interorganizational relationships, the strategic marketing vision on relationships can be very useful. At the same time however, the operationalization of these concepts requires special attention and a distinct role of the management of health-care organizations, because of the characteristics of such organizations and the specific type of their service delivery.

Accountable Care Organizations: what they mean for the country and for neurointerventionalists.

PubMed

Meehan, Timothy M; Harvey, H Benjamin; Duszak, Richard; Meyers, Philip M; McGinty, Geraldine; Nicola, Gregory N; Hirsch, Joshua A

2016-06-01

The Affordable Care Act is celebrating its fifth anniversary and remains one of the most significant attempts to reform healthcare in US history. Prior to the federal legislation, Accountable Care Organizations had largely been part of an academic discussion about how to control rising healthcare costs, but have since become a fixture in our national healthcare landscape. A fundamental shift is underway in the relationship between healthcare delivery and payment models. Some elements of Accountable Care Organizations may remain unfamiliar to most healthcare providers, including neurointerventional specialists. In this paper we review the fundamental concepts behind and the current forms of Accountable Care Organizations, and discuss the challenges and opportunities they present for neurointerventionalists. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Multi-organ autonomic dysfunction in Parkinson disease

PubMed Central

2010-01-01

Both pathologic and clinical studies of autonomic pathways have expanded the concept of Parkinson disease (PD) from a movement disorder to a multi-level widespread neurodegenerative process with non-motor features spanning several organ systems. This review integrates neuropathologic findings and autonomic physiology in PD as it relates to end organ autonomic function. Symptoms, pathology and physiology of the cardiovascular, skin/sweat gland, urinary, gastrointestinal, pupillary and neuroendocrine systems can be probed by autopsy, biopsy and non-invasive electrophysiological techniques in vivo which assess autonomic anatomy and function. There is mounting evidence that PD affects a chain of neurons in autonomic pathways. Consequently, autonomic physiology may serve as a window into non-motor PD progression and allow the development of mechanistically based treatment strategies for several non-motor features of PD. End-organ physiologic markers may be used to inform a model of PD pathophysiology and non-motor progression. PMID:20851033

Self Organized Criticality as a new paradigm of sleep regulation

NASA Astrophysics Data System (ADS)

Ivanov, Plamen Ch.; Bartsch, Ronny P.

2012-02-01

Humans and animals often exhibit brief awakenings from sleep (arousals), which are traditionally viewed as random disruptions of sleep caused by external stimuli or pathologic perturbations. However, our recent findings show that arousals exhibit complex temporal organization and scale-invariant behavior, characterized by a power-law probability distribution for their durations, while sleep stage durations exhibit exponential behavior. The co-existence of both scale-invariant and exponential processes generated by a single regulatory mechanism has not been observed in physiological systems until now. Such co-existence resembles the dynamical features of non-equilibrium systems exhibiting self-organized criticality (SOC). Our empirical analysis and modeling approaches based on modern concepts from statistical physics indicate that arousals are an integral part of sleep regulation and may be necessary to maintain and regulate healthy sleep by releasing accumulated excitations in the regulatory neuronal networks, following a SOC-type temporal organization.

The influence of instructional interactions on students’ mental models about the quantization of physical observables: a modern physics course case

NASA Astrophysics Data System (ADS)

Didiş Körhasan, Nilüfer; Eryılmaz, Ali; Erkoç, Şakir

2016-01-01

Mental models are coherently organized knowledge structures used to explain phenomena. They interact with social environments and evolve with the interaction. Lacking daily experience with phenomena, the social interaction gains much more importance. In this part of our multiphase study, we investigate how instructional interactions influenced students’ mental models about the quantization of physical observables. Class observations and interviews were analysed by studying students’ mental models constructed in a modern physics course during an academic semester. The research revealed that students’ mental models were influenced by (1) the manner of teaching, including instructional methodologies and content specific techniques used by the instructor, (2) order of the topics and familiarity with concepts, and (3) peers.

A novel and simple model of the uptake of organic chemicals by vegetation from air and soil.

PubMed

Hung, H; Mackay, D

1997-09-01

A novel and simple three-compartment fugacity model has been developed to predict the kinetics and equilibria of the uptake of organic chemicals in herbaceous agricultural plants at various times, including the time of harvest using only readily available input data. The chemical concentration in each of the three plant compartments leaf, stem which includes fruits and seeds, and root) is expressed as a function of both time and chemical concentrations in soil and air. The model was developed using the fugacity concept; however, the final expressions are presented in terms of concentrations in soil and air, equilibrium partition coefficients and a set of transport and transformation half-lives. An illustrative application of the model is presented which describes the uptake of bromacil by a soybean plant under hydroponic conditions. The model, which is believed to give acceptably accurate prediction of the distribution of chemicals among plant tissues, air and soil, may be used for the assessment of exposure to, and risk from contaminants consumed either directly from vegetation or indirectly in natural and agricultural food chains.

Processing of angular motion and gravity information through an internal model.

PubMed

Laurens, Jean; Straumann, Dominik; Hess, Bernhard J M

2010-09-01

The vestibular organs in the base of the skull provide important information about head orientation and motion in space. Previous studies have suggested that both angular velocity information from the semicircular canals and information about head orientation and translation from the otolith organs are centrally processed in an internal model of head motion, using the principles of optimal estimation. This concept has been successfully applied to model behavioral responses to classical vestibular motion paradigms. This study measured the dynamic of the vestibuloocular reflex during postrotatory tilt, tilt during the optokinetic afternystagmus, and off-vertical axis rotation. The influence of otolith signal on the VOR was systematically varied by using a series of tilt angles. We found that the time constants of responses varied almost identically as a function of gravity in these paradigms. We show that Bayesian modeling could predict the experimental results in an accurate and consistent manner. In contrast to other approaches, the Bayesian model also provides a plausible explanation of why these vestibulooculo motor responses occur as a consequence of an internal process of optimal motion estimation.

Neuronal pathway finding: from neurons to initial neural networks.

PubMed

Roscigno, Cecelia I

2004-10-01

Neuronal pathway finding is crucial for structured cellular organization and development of neural circuits within the nervous system. Neuronal pathway finding within the visual system has been extensively studied and therefore is used as a model to review existing knowledge regarding concepts of this developmental process. General principles of neuron pathway finding throughout the nervous system exist. Comprehension of these concepts guides neuroscience nurses in gaining an understanding of the developmental course of action, the implications of different anomalies, as well as the theoretical basis and nursing implications of some provocative new therapies being proposed to treat neurodegenerative diseases and neurologic injuries. These therapies have limitations in light of current ethical, developmental, and delivery modes and what is known about the development of neuronal pathways.

Taxonomy-Based Approaches to Quality Assurance of Ontologies

PubMed Central

Perl, Yehoshua; Ochs, Christopher

2017-01-01

Ontologies are important components of health information management systems. As such, the quality of their content is of paramount importance. It has been proven to be practical to develop quality assurance (QA) methodologies based on automated identification of sets of concepts expected to have higher likelihood of errors. Four kinds of such sets (called QA-sets) organized around the themes of complex and uncommonly modeled concepts are introduced. A survey of different methodologies based on these QA-sets and the results of applying them to various ontologies are presented. Overall, following these approaches leads to higher QA yields and better utilization of QA personnel. The formulation of additional QA-set methodologies will further enhance the suite of available ontology QA tools. PMID:29158885

HOT Faults", Fault Organization, and the Occurrence of the Largest Earthquakes

NASA Astrophysics Data System (ADS)

Carlson, J. M.; Hillers, G.; Archuleta, R. J.

2006-12-01

We apply the concept of "Highly Optimized Tolerance" (HOT) for the investigation of spatio-temporal seismicity evolution, in particular mechanisms associated with largest earthquakes. HOT provides a framework for investigating both qualitative and quantitative features of complex feedback systems that are far from equilibrium and punctuated by rare, catastrophic events. In HOT, robustness trade-offs lead to complexity and power laws in systems that are coupled to evolving environments. HOT was originally inspired by biology and engineering, where systems are internally very highly structured, through biological evolution or deliberate design, and perform in an optimum manner despite fluctuations in their surroundings. Though faults and fault systems are not designed in ways comparable to biological and engineered structures, feedback processes are responsible in a conceptually comparable way for the development, evolution and maintenance of younger fault structures and primary slip surfaces of mature faults, respectively. Hence, in geophysical applications the "optimization" approach is perhaps more aptly replaced by "organization", reflecting the distinction between HOT and random, disorganized configurations, and highlighting the importance of structured interdependencies that evolve via feedback among and between different spatial and temporal scales. Expressed in the terminology of the HOT concept, mature faults represent a configuration optimally organized for the release of strain energy; whereas immature, more heterogeneous fault networks represent intermittent, suboptimal systems that are regularized towards structural simplicity and the ability to generate large earthquakes more easily. We discuss fault structure and associated seismic response pattern within the HOT concept, and outline fundamental differences between this novel interpretation to more orthodox viewpoints like the criticality concept. The discussion is flanked by numerical simulations of a 2D fault model, where we investigate different feedback mechanisms and their effect on seismicity evolution. We introduce an approach to estimate the state of a fault and thus its capability of generating a large (system-wide) event assuming likely heterogeneous distributions of hypocenters and stresses, respectively.

Study on the removal of organic micropollutants from aqueous and ethanol solutions by HAP membranes with tunable hydrophilicity and hydrophobicity.

PubMed

He, Junyong; Li, Yulian; Cai, Xingguo; Chen, Kai; Zheng, Hejing; Wang, Chengming; Zhang, Kaisheng; Lin, Dongyue; Kong, Lingtao; Liu, Jinhuai

2017-05-01

A biocompatible and uniquely defined hydroxyapatite (HAP) adsorption membrane with a sandwich structure was developed for the removal of organic micropollutants for the first time. Both the adsorption and membrane technique were used for the removal of organic micropollutants. The hydrophilicity and hydrophobicity of the HAP adsorbent and membrane were tunable by controlling the surface structure of HAP. The adsorption of organic micropollutants on the HAP adsorbent was studied in batch experiments. The adsorption process was fit with the Freundlich model, while the adsorption kinetics followed the pseudo-second-order model. The HAP membrane could remove organic micropollutants effectively by dynamic adsorption in both aqueous and ethanol solutions. The removal efficiencies of organic micropollutants depended on the solution composition, membrane thickness and hydrophilicity, flow rate, and the initial concentration of organic micropollutants. The adsorption capacities of the HAP membrane with a sandwich structure (membrane thickness was 0.3 mm) were 6700, 6510, 6310, 5960, 5490, 5230, 4980 and 4360 L m -2 for 1-naphthyl amine, 2-naphthol, bisphenol S, propranolol hydrochloride, metolachlor, ethinyl oestradiol, 2,4-dichlorophenol and bisphenol A, respectively, when the initial concentration was 3.0 mg L -1 . The biocompatible HAP adsorption membrane can be easily regenerated by methanol and was thus demonstrated to be a novel concept for the removal of organic micropollutants from both aqueous and organic solutions. Copyright © 2017 Elsevier Ltd. All rights reserved.

Organic food processing: a framework for concept, starting definitions and evaluation.

PubMed

Kahl, Johannes; Alborzi, Farnaz; Beck, Alexander; Bügel, Susanne; Busscher, Nicolaas; Geier, Uwe; Matt, Darja; Meischner, Tabea; Paoletti, Flavio; Pehme, Sirli; Ploeger, Angelika; Rembiałkowska, Ewa; Schmid, Otto; Strassner, Carola; Taupier-Letage, Bruno; Załęcka, Aneta

2014-10-01

In 2007 EU Regulation (EC) 834/2007 introduced principles and criteria for organic food processing. These regulations have been analysed and discussed in several scientific publications and research project reports. Recently, organic food quality was described by principles, aspects and criteria. These principles from organic agriculture were verified and adapted for organic food processing. Different levels for evaluation were suggested. In another document, underlying paradigms and consumer perception of organic food were reviewed against functional food, resulting in identifying integral product identity as the underlying paradigm and a holistic quality view connected to naturalness as consumers' perception of organic food quality. In a European study, the quality concept was applied to the organic food chain, resulting in a problem, namely that clear principles and related criteria were missing to evaluate processing methods. Therefore the goal of this paper is to describe and discuss the topic of organic food processing to make it operational. A conceptual background for organic food processing is given by verifying the underlying paradigms and principles of organic farming and organic food as well as on organic processing. The proposed definition connects organic processing to related systems such as minimal, sustainable and careful, gentle processing, and describes clear principles and related criteria. Based on food examples, such as milk with different heat treatments, the concept and definitions were verified. Organic processing can be defined by clear paradigms and principles and evaluated according criteria from a multidimensional approach. Further work has to be done on developing indicators and parameters for assessment of organic food quality. © 2013 Society of Chemical Industry.

The Taba Curriculum Development Project in Social Studies; Development of a Comprehensive Curriculum Model for Social Studies for Grades One Through Eight Inclusive of Procedures for Implementation and Dissemination. Final Report.

ERIC Educational Resources Information Center

Wallen, Norman E.; And Others

One of the major focuses of this project was the revision of existing curriculum guides for grades one through six (the Contra Costa Social Studies Guides) and the development of guides for grades seven and eight. The emphases were: organization of learning activities under significant generalizations of main concepts; sequential treatment;…

Software Capability Evaluation (SCE) Version 2.0 Implementation Guide

DTIC Science & Technology

1994-02-01

Affected By SCE B-40 Figure 3-1 SCE Usage Decision Making Criteria 3-44 Figure 3-2 Estimated SCE Labor For One Source Selection 3-53 Figure 3-3 SCE...incorporated into the source selection sponsoring organization’s technical/management team for incorporation into acquisition decisions . The SCE team...expertise, past performance, and organizational capacity in acquisition decisions . The Capability Maturity Model Basic Concepts The CMM is based on the

Using the Cambridge Structural Database to Teach Molecular Geometry Concepts in Organic Chemistry

ERIC Educational Resources Information Center

Wackerly, Jay Wm.; Janowicz, Philip A.; Ritchey, Joshua A.; Caruso, Mary M.; Elliott, Erin L.; Moore, Jeffrey S.

2009-01-01

This article reports a set of two homework assignments that can be used in a second-year undergraduate organic chemistry class. These assignments were designed to help reinforce concepts of molecular geometry and to give students the opportunity to use a technological database and data mining to analyze experimentally determined chemical…

Examining the Conceptual Organization of Students in an Integrated Algebra and Physical Science Class.

ERIC Educational Resources Information Center

Westbrook, Susan L.

1998-01-01

Compares the conceptual organization of students in an integrated algebra and physical science class (SAM 9) with that of students in a discipline-specific physical science class (PSO). Analysis of students' concept maps indicates that the SAM9 students used a greater number of procedural linkages to connect mathematics and science concepts than…

Motor Knowledge Is One Dimension for Concept Organization: Further Evidence from a Chinese Semantic Dementia Case

ERIC Educational Resources Information Center

Lin, Nan; Guo, Qihao; Han, Zaizhu; Bi, Yanchao

2011-01-01

Neuropsychological and neuroimaging studies have indicated that motor knowledge is one potential dimension along which concepts are organized. Here we present further direct evidence for the effects of motor knowledge in accounting for categorical patterns across object domains (living vs. nonliving) and grammatical domains (nouns vs. verbs), as…

Medical Mycology and the Chemistry Classroom: Germinating Student Interest in Organic Chemistry

ERIC Educational Resources Information Center

Bliss, Joseph M.; Reid, Christopher W.

2013-01-01

Efforts to provide active research context to introductory courses in basic sciences are likely to better engage learners and provide a framework for relevant concepts. A simple teaching and learning experiment was conducted to use concepts in organic chemistry to solve problems in the life sciences. Bryant University is a liberal arts university…

Biology Teachers' Conceptions of the Diversity of Life and the Historical Development of Evolutionary Concepts

ERIC Educational Resources Information Center

da Silva, Paloma Rodrigues; de Andrade, Mariana A. Bologna Soares; de Andrade Caldeira, Ana Maria

2015-01-01

Biology is a science that involves study of the diversity of living organisms. This diversity has always generated questions and has motivated cultures to seek plausible explanations for the differences and similarities between types of organisms. In biology teaching, these issues are addressed by adopting an evolutionary approach. The aim of this…

Linking Reading and Writing: Concept Mapping as an Organizing Tactic.

ERIC Educational Resources Information Center

Osman-Jouchoux, Rionda

Writers often must summarize others' texts as part of their own work. To succeed at this, they must first read and understand new information and then transform that information to fulfill a specific purpose. Concept mapping, used as a visual organizing technique, can be an effective link between the two processes. In a preliminary study, students…