Role of orientation reference selection in motion sickness
NASA Technical Reports Server (NTRS)
Peterka, Robert J.; Black, F. Owen
1987-01-01
The objectives of this proposal were developed to further explore and quantify the orientation reference selection abilities of subjects and the relation, if any, between motion sickness and orientation reference selection. The overall objectives of this proposal are to determine (1) if motion sickness susceptibility is related to sensory orientation reference selection abilities of subjects, (2) if abnormal vertical canal-otolith function is the source of these abnormal posture control strategies and if it can be quantified by vestibular and oculomotor reflex measurements, and (3) if quantifiable measures of perception of vestibular and visual motion cues can be related to motion sickness susceptibility and to orientation reference selection ability demonstrated by tests which systematically control the sensory imformation available for orientation.
Role of orientation reference selection in motion sickness, supplement 2S
NASA Technical Reports Server (NTRS)
Peterka, Robert J.; Black, F. Owen
1987-01-01
Previous experiments with moving platform posturography have shown that different people have varying abilities to resolve conflicts among vestibular, visual, and proprioceptive sensory signals. The conceptual basis of the present proposal hinges on the similarities between the space motion sickness problem and the sensory orientation reference selection problems associated with benign paroxysmal positional vertigo (BPPV) syndrome. These similarities include both etiology related to abnormal vertical canal-otolith function, and motion sickness initiating events provoked by pitch and roll head movements. The objectives are to explore and quantify the orientation reference selection abilities of subjects and the relation of this selection to motion sickness in humans. The overall objectives are to determine: if motion sickness susceptibility is related to sensory orientation reference selection abilities of subjects; if abnormal vertical canal-otolith function is the source of abnormal posture control strategies and if it can be quantified by vestibular and oculomotor reflex measurements, and if it can be quantified by vestibular and oculomotor reflex measurements; and quantifiable measures of perception of vestibular and visual motion cues can be related to motion sickness susceptibility and to orientation reference selection ability.
Role of orientation reference selection in motion sickness
NASA Technical Reports Server (NTRS)
Peterka, Robert J.; Black, F. Owen
1990-01-01
Three areas related to human orientation control are investigated: (1) reflexes associated with the control of eye movements and posture; (2) the perception of body rotation and position with respect to gravity; and (3) the strategies used to resolve sensory conflict situations which arise when different sensory systems provide orientation cues which are not consistent with one another or with previous experience. Of particular interest is the possibility that a subject may be able to ignore an inaccurate sensory modality in favor of one or more other sensory modalities which do provide accurate orientation reference information. This process is referred as sensory selection. This proposal will attempt to quantify subject's sensory selection abilities and determine if this ability confers some immunity to the development of motion sickness symptoms.
ERIC Educational Resources Information Center
Kelly, Jonathan W.; Sjolund, Lori A.; Sturz, Bradley R.
2013-01-01
Spatial memories are often organized around reference frames, and environmental shape provides a salient cue to reference frame selection. To date, however, the environmental cues responsible for influencing reference frame selection remain relatively unknown. To connect research on reference frame selection with that on orientation via…
Object Orientation Affects Spatial Language Comprehension
ERIC Educational Resources Information Center
Burigo, Michele; Sacchi, Simona
2013-01-01
Typical spatial descriptions, such as "The car is in front of the house," describe the position of a located object (LO; e.g., the car) in space relative to a reference object (RO) whose location is known (e.g., the house). The orientation of the RO affects spatial language comprehension via the reference frame selection process.…
Role of orientation reference selection in motion sickness
NASA Technical Reports Server (NTRS)
Peterka, Robert J.; Black, F. Owen
1988-01-01
Previous experiments with moving platform posturography have shown that different people have varying abilities to resolve conflicts among vestibular, visual, and proprioceptive sensory signals used to control upright posture. In particular, there is one class of subjects with a vestibular disorder known as benign paroxysmal positional vertigo (BPPV) who often are particularly sensitive to inaccurate visual information. That is, they will use visual sensory information for the control of their posture even when that visual information is inaccurate and is in conflict with accurate proprioceptive and vestibular sensory signals. BPPV has been associated with disorders of both posterior semicircular canal function and possibly otolith function. The present proposal hopes to take advantage of the similarities between the space motion sickness problem and the sensory orientation reference selection problems associated with the BPPV syndrome. These similarities include both etiology related to abnormal vertical canal-otolith function, and motion sickness initiating events provoked by pitch and roll head movements. The objectives of this proposal are to explore and quantify the orientation reference selection abilities of subjects and the relation of this selection to motion sickness in humans.
Object orientation affects spatial language comprehension.
Burigo, Michele; Sacchi, Simona
2013-01-01
Typical spatial descriptions, such as "The car is in front of the house," describe the position of a located object (LO; e.g., the car) in space relative to a reference object (RO) whose location is known (e.g., the house). The orientation of the RO affects spatial language comprehension via the reference frame selection process. However, the effects of the LO's orientation on spatial language have not received great attention. This study explores whether the pure geometric information of the LO (e.g., its orientation) affects spatial language comprehension using placing and production tasks. Our results suggest that the orientation of the LO influences spatial language comprehension even in the absence of functional relationships. Copyright © 2013 Cognitive Science Society, Inc.
Role of orientation reference selection in motion sickness
NASA Technical Reports Server (NTRS)
Peterka, Robert J.; Black, F. Owen
1992-01-01
The overall objective of this proposal is to understand the relationship between human orientation control and motion sickness susceptibility. Three areas related to orientation control will be investigated. These three areas are (1) reflexes associated with the control of eye movements and posture, (2) the perception of body rotation and position with respect to gravity, and (3) the strategies used to resolve sensory conflict situations which arise when different sensory systems provide orientation cues which are not consistent with one another or with previous experience. Of particular interest is the possibility that a subject may be able to ignore an inaccurate sensory modality in favor of one or more other sensory modalities which do provide accurate orientation reference information. We refer to this process as sensory selection. This proposal will attempt to quantify subjects' sensory selection abilities and determine if this ability confers some immunity to the development of motion sickness symptoms. Measurements of reflexes, motion perception, sensory selection abilities, and motion sickness susceptibility will concentrate on pitch and roll motions since these seem most relevant to the space motion sickness problem. Vestibulo-ocular (VOR) and oculomotor reflexes will be measured using a unique two-axis rotation device developed in our laboratory over the last seven years. Posture control reflexes will be measured using a movable posture platform capable of independently altering proprioceptive and visual orientation cues. Motion perception will be quantified using closed loop feedback technique developed by Zacharias and Young (Exp Brain Res, 1981). This technique requires a subject to null out motions induced by the experimenter while being exposed to various confounding sensory orientation cues. A subject's sensory selection abilities will be measured by the magnitude and timing of his reactions to changes in sensory environments. Motion sickness susceptibility will be measured by the time required to induce characteristic changes in the pattern of electrogastrogram recordings while exposed to various sensory environments during posture and motion perception tests. The results of this work are relevant to NASA's interest in understanding the etiology of space motion sickness. If any of the reflex, perceptual, or sensory selection abilities of subjects are found to correlate with motion sickness susceptibility, this work may be an important step in suggesting a method of predicting motion sickness susceptibility. If sensory selection can provide a means to avoid sensory conflict, then further work may lead to training programs which could enhance a subject's sensory selection ability and therefore minimize motion sickness susceptibility.
Gonzalo Cogno, Soledad; Mato, Germán
2015-01-01
Orientation selectivity is ubiquitous in the primary visual cortex (V1) of mammals. In cats and monkeys, V1 displays spatially ordered maps of orientation preference. Instead, in mice, squirrels, and rats, orientation selective neurons in V1 are not spatially organized, giving rise to a seemingly random pattern usually referred to as a salt-and-pepper layout. The fact that such different organizations can sharpen orientation tuning leads to question the structural role of the intracortical connections; specifically the influence of plasticity and the generation of functional connectivity. In this work, we analyze the effect of plasticity processes on orientation selectivity for both scenarios. We study a computational model of layer 2/3 and a reduced one-dimensional model of orientation selective neurons, both in the balanced state. We analyze two plasticity mechanisms. The first one involves spike-timing dependent plasticity (STDP), while the second one considers the reconnection of the interactions according to the preferred orientations of the neurons. We find that under certain conditions STDP can indeed improve selectivity but it works in a somehow unexpected way, that is, effectively decreasing the modulated part of the intracortical connectivity as compared to the non-modulated part of it. For the reconnection mechanism we find that increasing functional connectivity leads, in fact, to a decrease in orientation selectivity if the network is in a stable balanced state. Both counterintuitive results are a consequence of the dynamics of the balanced state. We also find that selectivity can increase due to a reconnection process if the resulting connections give rise to an unstable balanced state. We compare these findings with recent experimental results. PMID:26347615
Safety Factors in Educational Facilities. An Annotated Reference List.
ERIC Educational Resources Information Center
Wakefield, Howard E.
Abstracts and descriptor terms are presented for 26 selected references with safety orientation. Included in addition to several general planning handbooks are topics related to--(1) stairways, (2) air structures, (3) site planning, (4) lighting, (5) bidding practice, (6) physically handicapped, (7) laboratory design, (8) mobile classrooms, (9)…
Rada, E C; Ragazzi, M; Fedrizzi, P
2013-04-01
Municipal solid waste management is a multidisciplinary activity that includes generation, source separation, storage, collection, transfer and transport, processing and recovery, and, last but not least, disposal. The optimization of waste collection, through source separation, is compulsory where a landfill based management must be overcome. In this paper, a few aspects related to the implementation of a Web-GIS based system are analyzed. This approach is critically analyzed referring to the experience of two Italian case studies and two additional extra-European case studies. The first case is one of the best examples of selective collection optimization in Italy. The obtained efficiency is very high: 80% of waste is source separated for recycling purposes. In the second reference case, the local administration is going to be faced with the optimization of waste collection through Web-GIS oriented technologies for the first time. The starting scenario is far from an optimized management of municipal solid waste. The last two case studies concern pilot experiences in China and Malaysia. Each step of the Web-GIS oriented strategy is comparatively discussed referring to typical scenarios of developed and transient economies. The main result is that transient economies are ready to move toward Web oriented tools for MSW management, but this opportunity is not yet well exploited in the sector. Copyright © 2013 Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rada, E.C., E-mail: Elena.Rada@ing.unitn.it; Ragazzi, M.; Fedrizzi, P.
Highlights: ► As an appropriate solution for MSW management in developed and transient countries. ► As an option to increase the efficiency of MSW selective collection. ► As an opportunity to integrate MSW management needs and services inventories. ► As a tool to develop Urban Mining actions. - Abstract: Municipal solid waste management is a multidisciplinary activity that includes generation, source separation, storage, collection, transfer and transport, processing and recovery, and, last but not least, disposal. The optimization of waste collection, through source separation, is compulsory where a landfill based management must be overcome. In this paper, a few aspectsmore » related to the implementation of a Web-GIS based system are analyzed. This approach is critically analyzed referring to the experience of two Italian case studies and two additional extra-European case studies. The first case is one of the best examples of selective collection optimization in Italy. The obtained efficiency is very high: 80% of waste is source separated for recycling purposes. In the second reference case, the local administration is going to be faced with the optimization of waste collection through Web-GIS oriented technologies for the first time. The starting scenario is far from an optimized management of municipal solid waste. The last two case studies concern pilot experiences in China and Malaysia. Each step of the Web-GIS oriented strategy is comparatively discussed referring to typical scenarios of developed and transient economies. The main result is that transient economies are ready to move toward Web oriented tools for MSW management, but this opportunity is not yet well exploited in the sector.« less
Selecting a Persistent Data Support Environment for Object-Oriented Applications
1998-03-01
key features of most object DBMS products is contained in the <DWAS 9{eeds Assessment for Objects from Barry and Associates. The developer should...data structure and behavior in a self- contained module enhances maintainability of the system and promotes reuse of modules for similar domains...considered together, represent a survey of commercial object-oriented database management systems. These references contain detailed information needed
The Environment Film Review. A Critical Guide to Ecology Films.
ERIC Educational Resources Information Center
Environment Information Center, New York, NY.
Critical reviews of more than 600 environmental films selected from a field of several thousand are contained in this reference guide. Designed to provide a comprehensive selection of films covering all aspects of environmental affairs, from air pollution to wildlife, the guide is primarily user-oriented. It consists of two parts: a Review…
NASA Astrophysics Data System (ADS)
Paszkiewicz, Zbigniew; Picard, Willy
Performance management (PM) is a key function of virtual organization (VO) management. A large set of PM indicators has been proposed and evaluated within the context of virtual breeding environments (VBEs). However, it is currently difficult to describe and select suitable PM indicators because of the lack of a common vocabulary and taxonomies of PM indicators. Therefore, there is a need for a framework unifying concepts in the domain of VO PM. In this paper, a reference model for VO PM is presented in the context of service-oriented VBEs. In the proposed reference model, both a set of terms that could be used to describe key performance indicators, and a set of taxonomies reflecting various aspects of PM are proposed. The proposed reference model is a first attempt and a work in progress that should not be supposed exhaustive.
Reduction of photographic observations of asteroids to the reference frame of a single catalog
NASA Astrophysics Data System (ADS)
Chernetenko, Yu. A.
2008-04-01
In 2000, the last international program of photographic observations of selected asteroids aimed at the determination of the mutual orientation of the dynamic and stellar coordinate systems came to an end. The Institute of Applied Astronomy of the Russian Academy of Sciences collected more than 25 000 observations for 15 asteroids spanning from 1949 through 1995. These observations were reduced to the reference frame of the Hipparcos catalog using dependencies published along with observations. The accuracy of observations of selected asteroids was 0.30 arcsec, which is comparable to that of modern CCD observations of minor planets. The observations are available at
Heterogeneity among violence-exposed women: applying person-oriented research methods.
Nurius, Paula S; Macy, Rebecca J
2008-03-01
Variability of experience and outcomes among violence-exposed people pose considerable challenges toward developing effective prevention and treatment protocols. To address these needs, the authors present an approach to research and a class of methodologies referred to as person oriented. Person-oriented tools support assessment of meaningful patterns among people that distinguish one group from another, subgroups for whom different interventions are indicated. The authors review the conceptual base of person-oriented methods, outline their distinction from more familiar variable-oriented methods, present descriptions of selected methods as well as empirical applications of person-oriented methods germane to violence exposure, and conclude with discussion of implications for future research and translation between research and practice. The authors focus on violence against women as a population, drawing on stress and coping theory as a theoretical framework. However, person-oriented methods hold utility for investigating diversity among violence-exposed people's experiences and needs across populations and theoretical foundations.
Ballemans, Judith; Kempen, Gertrudis IJM; Zijlstra, GA Rixt
2011-01-01
Objective: This study aimed to provide an overview of the development, content, feasibility, and effectiveness of existing orientation and mobility training programmes in the use of the identification cane. Data sources: A systematic bibliographic database search in PubMed, PsychInfo, ERIC, CINAHL and the Cochrane Library was performed, in combination with the expert consultation (n = 42; orientation and mobility experts), and hand-searching of reference lists. Review methods: Selection criteria included a description of the development, the content, the feasibility, or the effectiveness of orientation and mobility training in the use of the identification cane. Two reviewers independently agreed on eligibility and methodological quality. A narrative/qualitative data analysis method was applied to extract data from obtained documents. Results: The sensitive database search and hand-searching of reference lists revealed 248 potentially relevant abstracts. None met the eligibility criteria. Expert consultation resulted in the inclusion of six documents in which the information presented on the orientation and mobility training in the use of the identification cane was incomplete and of low methodological quality. Conclusion: Our review of the literature showed a lack of well-described protocols and studies on orientation and mobility training in identification cane use. PMID:21795405
Woman: Yesterday, Today, Tomorrow.
ERIC Educational Resources Information Center
Reinfeld, Patricia M.
This booklet on the status of women, aimed at raising the consciousness of female college students, provides an orientation to feminism and references for further pursuit of the areas covered in the following sections. "On Woman and Her Role" sets the stage with selected quotations, expressing conflicting views of woman's role. "What It Is All…
The manual can be used to orient personnel involved in inspecting and otherwise evaluating potential toxic chemical release hazards to the fundamentals of release hazard control for 13 of the specific chemicals chosen for evaluation under Section 305(b) of the Superfund Amendment...
Working as a Plumber; Construction 7-9--Prevocational: 5846.09.
ERIC Educational Resources Information Center
Dade County Public Schools, Miami, FL.
The beginning course involves the student with practices in plumbing, referring to the various systems of pipes and tubes that carry liquids and gases from a source to a building. Course content includes goals, specific objectives, orientation, selecting hardware, tools and equipment, prescription for faulty fixtures, and plumbing installations.…
NASA Technical Reports Server (NTRS)
1971-01-01
Preliminary design and analysis of purge system concepts and purge subsystem approaches are defined and evaluated. Acceptable purge subsystem approaches were combined into four predesign layouts which are presented for comparison and evaluation. Two predesigns were selected for further detailed design and evaluation for eventual selection of the best design for a full scale test configuration. An operation plan is included as an appendix for reference to shuttle-oriented operational parameters.
Establishing the behavioural limits for countershaded camouflage.
Penacchio, Olivier; Harris, Julie M; Lovell, P George
2017-10-20
Countershading is a ubiquitous patterning of animals whereby the side that typically faces the highest illumination is darker. When tuned to specific lighting conditions and body orientation with respect to the light field, countershading minimizes the gradient of light the body reflects by counterbalancing shadowing due to illumination, and has therefore classically been thought of as an adaptation for visual camouflage. However, whether and how crypsis degrades when body orientation with respect to the light field is non-optimal has never been studied. We tested the behavioural limits on body orientation for countershading to deliver effective visual camouflage. We asked human participants to detect a countershaded target in a simulated three-dimensional environment. The target was optimally coloured for crypsis in a reference orientation and was displayed at different orientations. Search performance dramatically improved for deviations beyond 15 degrees. Detection time was significantly shorter and accuracy significantly higher than when the target orientation matched the countershading pattern. This work demonstrates the importance of maintaining body orientation appropriate for the displayed camouflage pattern, suggesting a possible selective pressure for animals to orient themselves appropriately to enhance crypsis.
From scenarios to domain models: processes and representations
NASA Astrophysics Data System (ADS)
Haddock, Gail; Harbison, Karan
1994-03-01
The domain specific software architectures (DSSA) community has defined a philosophy for the development of complex systems. This philosophy improves productivity and efficiency by increasing the user's role in the definition of requirements, increasing the systems engineer's role in the reuse of components, and decreasing the software engineer's role to the development of new components and component modifications only. The scenario-based engineering process (SEP), the first instantiation of the DSSA philosophy, has been adopted by the next generation controller project. It is also the chosen methodology of the trauma care information management system project, and the surrogate semi-autonomous vehicle project. SEP uses scenarios from the user to create domain models and define the system's requirements. Domain knowledge is obtained from a variety of sources including experts, documents, and videos. This knowledge is analyzed using three techniques: scenario analysis, task analysis, and object-oriented analysis. Scenario analysis results in formal representations of selected scenarios. Task analysis of the scenario representations results in descriptions of tasks necessary for object-oriented analysis and also subtasks necessary for functional system analysis. Object-oriented analysis of task descriptions produces domain models and system requirements. This paper examines the representations that support the DSSA philosophy, including reference requirements, reference architectures, and domain models. The processes used to create and use the representations are explained through use of the scenario-based engineering process. Selected examples are taken from the next generation controller project.
Geometry and Mechanics of Chiral Pod Opening
NASA Astrophysics Data System (ADS)
Sharon, Eran; Armon, Shahaf; Efrati, Efi; Kupferman, Raz
2012-02-01
We study the geometry and mechanics that drive the opening of Bauhinia seeds pods. The pod valve wall consists of two fibrous layers oriented at ± 45^o with respect to the pod axis. Upon drying, each of the layers shrinks uniaxially, perpendicularly to the fibers orientation. This active deformation turn the valve into an incompatible sheet with reference saddle-like curvature tensor and a flat (Euclidean) reference metric. These two intrinsic properties are incompatible. The shape is, therefore, selected by a stretching-bending competition. Strips cut from the valve tissue and from synthetic model material adopt various helical configurations. We provide analytical expressions for these configurations in the bending and stretching dominated regimes. Surface measurements show the transition from minimal surfaces (narrow limit) to cylindrical ones (wide limit). Finally, we show how plants use these mechanical principles using different tissue architectures.
Getting a Handle on Learning Anatomy with Interactive Three-Dimensional Graphics
ERIC Educational Resources Information Center
Stull, Andrew T.; Hegarty, Mary; Mayer, Richard E.
2009-01-01
In 2 experiments, participants learned bone anatomy by using a handheld controller to rotate an on-screen 3-dimensional bone model. The on-screen bone either included orientation references, which consisted of visible lines marking its axes (orientation reference condition), or did not include such references (no-orientation reference condition).…
Environmental apsects of the transuranics: a selected, annotated bibliography
DOE Office of Scientific and Technical Information (OSTI.GOV)
Martin, F. M.; Sanders, C. T.; Talmage, S. S.
This fourth published bibliography of 528 references is from the computer information file built to provide support to the Nevada Applied Ecology Group (NAEG) of the AEC Nevada Operations Office. The general scope is environmental aspects of uranium and the transuranic elements, with a preponderance of material on plutonium. In addition, there are supporting materials involving basic ecology or general reviews on other nuclides that are entered at the request of the NAEG. References provide findings-oriented abstracts. Numerical data is referred to, in the comment field. Indexes are given for author, subject category, keywords, geographic location, permuted title, taxons, andmore » publication description.« less
ERIC Educational Resources Information Center
Nagy, Gabriel; Trautwein, Ulrich; Baumert, Jurgen; Koller, Olaf; Garrett, Jessica
2006-01-01
Predictions about processes linking gender to students' choices of advanced courses were derived from the internal/external frame of reference (I/E) model and expectancy value (EV) theory. The predictions were tested for the domains of mathematics and biology using data from 1,148 students attending academically oriented secondary schools in…
ERIC Educational Resources Information Center
Bernstein, Susan; And Others
This report contains 20 summary-descriptions of curriculum programs and materials selected by the Institute for possible inclusion in its synthesis and validation of a K-6 process-promoting curriculum. Each description includes information on the developer and publisher plus a list of references (mostly published descriptions and critiques).…
Long-Term Variations of the EOP and ICRF2
NASA Technical Reports Server (NTRS)
Zharov, Vladimir; Sazhin, Mikhail; Sementsov, Valerian; Sazhina, Olga
2010-01-01
We analyzed the time series of the coordinates of the ICRF radio sources. We show that part of the radio sources, including the defining sources, shows a significant apparent motion. The stability of the celestial reference frame is provided by a no-net-rotation condition applied to the defining sources. In our case this condition leads to a rotation of the frame axes with time. We calculated the effect of this rotation on the Earth orientation parameters (EOP). In order to improve the stability of the celestial reference frame we suggest a new method for the selection of the defining sources. The method consists of two criteria: the first one we call cosmological and the second one kinematical. It is shown that a subset of the ICRF sources selected according to cosmological criteria provides the most stable reference frame for the next decade.
Environmental Inversion Effects in Face Perception
ERIC Educational Resources Information Center
Davidenko, Nicolas; Flusberg, Stephen J.
2012-01-01
Visual processing is highly sensitive to stimulus orientation; for example, face perception is drastically worse when faces are oriented inverted vs. upright. However, stimulus orientation must be established in relation to a particular reference frame, and in most studies, several reference frames are conflated. Which reference frame(s) matter in…
ERIC Educational Resources Information Center
Outcalt, Charles L., Ed.; Faris, Shannon K., Ed.; McMahon, Kathleen N., Ed.
The selections in this volume explain how, through service learning, residential living, community work, and student organizations, students can become leaders and more effective citizens. The chapters are: (1) "An Interview with Helen S. Astin" (Kathleen N. McMahon); (2) "The Emergence of Inclusive, Process-Oriented Leadership" (Shannon K. Faris…
INFOL for the CDC 6400 Information Storage and Retrieval System. Reference Manual.
ERIC Educational Resources Information Center
Mittman, B.; And Others
INFOL for the CDC 6400 is a rewrite in FORTRAN IV of the CDC 3600/3800 INFOL (Information Oriented Language), a generalized information storage and retrieval system developed by the Control Data Corporation for the CDC 3600/3800 computer. With INFOL, selected pieces of information are extracted from a file and presented to the user quickly and…
Evaluation of oriented lysozyme immobilized with monoclonal antibody
NASA Astrophysics Data System (ADS)
Aoyagi, Satoka; Okada, Keigo; Shigyo, Ayako; Man, Naoki; Karen, Akiya
2008-12-01
The orientation of a lysozyme immobilized with a monoclonal antibody was evaluated based on determination of the uppermost surface structure using time-of-flight secondary ion mass spectrometry (TOF-SIMS). Specific peaks of the oriented lysozyme immobilized with monoclonal anti-lysozyme antibody were obtained in comparison with reference samples, non-oriented immobilized lysozyme and immobilized anti-lysozyme antibody. All samples were freeze-dried before TOF-SIMS measurement, and then each sample was measured using TOF-SIMS with a bismuth cluster ion source. TOF-SIMS spectra were analyzed to select peaks specific to the oriented immobilized lysozyme as well as to identify their chemical formula and ensemble of amino acids. The possible chemical formulae of the lysozyme fragments were then investigated with an element matching program and a residue matching program. The results from TOF-SIMS spectra analysis were compared to the amino acid sequence of the lysozyme and its three-dimensional structure registered in the protein data bank. Finally, the fragment-ion-generating regions of the oriented immobilized lysozyme were determined based on the suggested residues and the three-dimensional structure.
Lin, Hsiu-Hsia; Chuang, Ya-Fang; Weng, Jing-Ling; Lo, Lun-Jou
2015-01-01
Background Three-dimensional computed tomographic imaging has become popular in clinical evaluation, treatment planning, surgical simulation, and outcome assessment for maxillofacial intervention. The purposes of this study were to investigate whether there is any correlation among landmark-based horizontal reference planes and to validate the reproducibility and reliability of landmark identification. Materials and Methods Preoperative and postoperative cone-beam computed tomographic images of patients who had undergone orthognathic surgery were collected. Landmark-oriented reference planes including the Frankfort horizontal plane (FHP) and the lateral semicircular canal plane (LSP) were established. Four FHPs were defined by selecting 3 points from the orbitale, porion, or midpoint of paired points. The LSP passed through both the lateral semicircular canal points and nasion. The distances between the maxillary or mandibular teeth and the reference planes were measured, and the differences between the 2 sides were calculated and compared. The precision in locating the landmarks was evaluated by performing repeated tests, and the intraobserver reproducibility and interobserver reliability were assessed. Results A total of 30 patients with facial deformity and malocclusion—10 patients with facial symmetry, 10 patients with facial asymmetry, and 10 patients with cleft lip and palate—were recruited. Comparing the differences among the 5 reference planes showed no statistically significant difference among all patient groups. Regarding intraobserver reproducibility, the mean differences in the 3 coordinates varied from 0 to 0.35 mm, with correlation coefficients between 0.96 and 1.0, showing high correlation between repeated tests. Regarding interobserver reliability, the mean differences among the 3 coordinates varied from 0 to 0.47 mm, with correlation coefficients between 0.88 and 1.0, exhibiting high correlation between the different examiners. Conclusions The 5 horizontal reference planes were reliable and comparable for 3D craniomaxillofacial analysis. These reference planes were useful in standardizing the orientation of 3D skull models. PMID:25668209
Lin, Hsiu-Hsia; Chuang, Ya-Fang; Weng, Jing-Ling; Lo, Lun-Jou
2015-01-01
Three-dimensional computed tomographic imaging has become popular in clinical evaluation, treatment planning, surgical simulation, and outcome assessment for maxillofacial intervention. The purposes of this study were to investigate whether there is any correlation among landmark-based horizontal reference planes and to validate the reproducibility and reliability of landmark identification. Preoperative and postoperative cone-beam computed tomographic images of patients who had undergone orthognathic surgery were collected. Landmark-oriented reference planes including the Frankfort horizontal plane (FHP) and the lateral semicircular canal plane (LSP) were established. Four FHPs were defined by selecting 3 points from the orbitale, porion, or midpoint of paired points. The LSP passed through both the lateral semicircular canal points and nasion. The distances between the maxillary or mandibular teeth and the reference planes were measured, and the differences between the 2 sides were calculated and compared. The precision in locating the landmarks was evaluated by performing repeated tests, and the intraobserver reproducibility and interobserver reliability were assessed. A total of 30 patients with facial deformity and malocclusion--10 patients with facial symmetry, 10 patients with facial asymmetry, and 10 patients with cleft lip and palate--were recruited. Comparing the differences among the 5 reference planes showed no statistically significant difference among all patient groups. Regarding intraobserver reproducibility, the mean differences in the 3 coordinates varied from 0 to 0.35 mm, with correlation coefficients between 0.96 and 1.0, showing high correlation between repeated tests. Regarding interobserver reliability, the mean differences among the 3 coordinates varied from 0 to 0.47 mm, with correlation coefficients between 0.88 and 1.0, exhibiting high correlation between the different examiners. The 5 horizontal reference planes were reliable and comparable for 3D craniomaxillofacial analysis. These reference planes were useful in standardizing the orientation of 3D skull models.
Updating of visual orientation in a gravity-based reference frame.
Niehof, Nynke; Tramper, Julian J; Doeller, Christian F; Medendorp, W Pieter
2017-10-01
The brain can use multiple reference frames to code line orientation, including head-, object-, and gravity-centered references. If these frames change orientation, their representations must be updated to keep register with actual line orientation. We tested this internal updating during head rotation in roll, exploiting the rod-and-frame effect: The illusory tilt of a vertical line surrounded by a tilted visual frame. If line orientation is stored relative to gravity, these distortions should also affect the updating process. Alternatively, if coding is head- or frame-centered, updating errors should be related to the changes in their orientation. Ten subjects were instructed to memorize the orientation of a briefly flashed line, surrounded by a tilted visual frame, then rotate their head, and subsequently judge the orientation of a second line relative to the memorized first while the frame was upright. Results showed that updating errors were mostly related to the amount of subjective distortion of gravity at both the initial and final head orientation, rather than to the amount of intervening head rotation. In some subjects, a smaller part of the updating error was also related to the change of visual frame orientation. We conclude that the brain relies primarily on a gravity-based reference to remember line orientation during head roll.
Sustainable reduction of bioreactor contamination in an industrial fermentation pilot plant.
Junker, Beth; Lester, Michael; Leporati, James; Schmitt, John; Kovatch, Michael; Borysewicz, Stan; Maciejak, Waldemar; Seeley, Anna; Hesse, Michelle; Connors, Neal; Brix, Thomas; Creveling, Eric; Salmon, Peter
2006-10-01
Facility experience primarily in drug-oriented fermentation equipment (producing small molecules such as secondary metabolites, bioconversions, and enzymes) and, to a lesser extent, in biologics-oriented fermentation equipment (producing large molecules such as recombinant proteins and microbial vaccines) in an industrial fermentation pilot plant over the past 15 years is described. Potential approaches for equipment design and maintenance, operational procedures, validation/verification testing, medium selection, culture purity/sterility analysis, and contamination investigation are presented, and those approaches implemented are identified. Failure data collected for pilot plant operation for nearly 15 years are presented and best practices for documentation and tracking are outlined. This analysis does not exhaustively discuss available design, operational and procedural options; rather it selectively presents what has been determined to be beneficial in an industrial pilot plant setting. Literature references have been incorporated to provide background and context where appropriate.
A framework for risk assessment and decision-making strategies in dangerous good transportation.
Fabiano, B; Currò, F; Palazzi, E; Pastorino, R
2002-07-01
The risk from dangerous goods transport by road and strategies for selecting road load/routes are faced in this paper, by developing an original site-oriented framework of general applicability at local level. A realistic evaluation of the frequency must take into account on one side inherent factors (e.g. tunnels, rail bridges, bend radii, slope, characteristics of neighborhood, etc.) on the other side factors correlated to the traffic conditions (e.g. dangerous goods trucks, etc.). Field data were collected on the selected highway, by systematic investigation, providing input data for a database reporting tendencies and intrinsic parameter/site-oriented statistics. The developed technique was applied to a pilot area, considering both the individual risk and societal risk and making reference to flammable and explosive scenarios. In this way, a risk assessment, sensitive to route features and population exposed, is proposed, so that the overall uncertainties in risk analysis can be lowered.
Analysis of the Motion Control Methods for Stratospheric Balloon-Borne Gondola Platform
NASA Astrophysics Data System (ADS)
Wang, H. H.; Yuan, Z. H.; Wu, J.
2006-10-01
At present, gondola platform is one of the stratospheric balloon-borne platforms being in research focus at home and overseas. Comparing to other stratospheric balloon-borne platforms, such as airship platform, gondola platform has advantages of higher stability, rapid in motion regulation and lower energy cost but disadvantages of less supporting capacity and be incapable of fixation. While all platforms have the same goal of keeping them at accurate angle and right pose for the requirements of instruments and objects installed in the platforms, when platforms rotate round the ground level perpendicular. That is accomplishing motion control. But, platform control system has factors of low damper, excessive and uncertain disturbances by the reason of its being hung over balloon in the air, it is hard to achieve the desired control precision because platform is ease to deviate its benchmark motion. Thus, in the controlling procedure in order to get higher precision, it is crucial to perceive the platform's swing synchronously and rapidly, and restrain the influence of disturbances effectively, keep the platform's pose steadily. Furthermore, while the platform in the air regard control center in the ground as reference object, it is ultimate to select a appropriate reference frame and work out the coordinates and implement the adjustment by the PC104 controller. This paper introduces the methods of the motion control based on stratospheric balloon-borne gondola platform. Firstly, this paper compares the characteristic of the flywheel and CMG and specifies the key methods of obtaining two significant states which are 'orientation stability' state and 'orientation tracking' state for platform motion control procedure using CMG as the control actuator. These two states reduce the deviation amplitude of rotation and swing of gondola's motion relative to original motion due to stratospheric intense atmosphere disturbance. We define it as the first procedure. In next procedure, we use the transfer matrix of earth reference frame to geographic reference frame to transform the data measured by the magnetic orientation sensors and the gyroscope to the space orientations, then the PC104 controller use the space orientations value as feedback to complete revises.
Orientation selectivity of synaptic input to neurons in mouse and cat primary visual cortex.
Tan, Andrew Y Y; Brown, Brandon D; Scholl, Benjamin; Mohanty, Deepankar; Priebe, Nicholas J
2011-08-24
Primary visual cortex (V1) is the site at which orientation selectivity emerges in mammals: visual thalamus afferents to V1 respond equally to all stimulus orientations, whereas their target V1 neurons respond selectively to stimulus orientation. The emergence of orientation selectivity in V1 has long served as a model for investigating cortical computation. Recent evidence for orientation selectivity in mouse V1 opens cortical computation to dissection by genetic and imaging tools, but also raises two essential questions: (1) How does orientation selectivity in mouse V1 neurons compare with that in previously described species? (2) What is the synaptic basis for orientation selectivity in mouse V1? A comparison of orientation selectivity in mouse and in cat, where such measures have traditionally been made, reveals that orientation selectivity in mouse V1 is weaker than in cat V1, but that spike threshold plays a similar role in narrowing selectivity between membrane potential and spike rate. To uncover the synaptic basis for orientation selectivity, we made whole-cell recordings in vivo from mouse V1 neurons, comparing neuronal input selectivity-based on membrane potential, synaptic excitation, and synaptic inhibition-to output selectivity based on spiking. We found that a neuron's excitatory and inhibitory inputs are selective for the same stimulus orientations as is its membrane potential response, and that inhibitory selectivity is not broader than excitatory selectivity. Inhibition has different dynamics than excitation, adapting more rapidly. In neurons with temporally modulated responses, the timing of excitation and inhibition was different in mice and cats.
Orientation Selectivity of Synaptic Input to Neurons in Mouse and Cat Primary Visual Cortex
Tan (陈勇毅), Andrew Y. Y.; Brown, Brandon D.; Scholl, Benjamin; Mohanty, Deepankar; Priebe, Nicholas J.
2011-01-01
Primary visual cortex (V1) is the site at which orientation selectivity emerges in mammals: visual thalamus afferents to V1 respond equally to all stimulus orientations whereas their target V1 neurons respond selectively to stimulus orientation. The emergence of orientation selectivity in V1 has long served as a model for investigating cortical computation. Recent evidence for orientation selectivity in mouse V1 opens cortical computation to dissection by genetic and imaging tools, but also raises two essential questions: 1) how does orientation selectivity in mouse V1 neurons compare with that in previously described species? 2) what is the synaptic basis for orientation selectivity in mouse V1? A comparison of orientation selectivity in mouse and in cat, where such measures have traditionally been made, reveals that orientation selectivity in mouse V1 is weaker than in cat V1, but that spike threshold plays a similar role in narrowing selectivity between membrane potential and spike rate. To uncover the synaptic basis for orientation selectivity, we made whole-cell recordings in vivo from mouse V1 neurons, comparing neuronal input selectivity - based on membrane potential, synaptic excitation, and synaptic inhibition - to output selectivity based on spiking. We found that a neuron's excitatory and inhibitory inputs are selective for the same stimulus orientations as is its membrane potential response, and that inhibitory selectivity is not broader than excitatory selectivity. Inhibition has different dynamics than excitation, adapting more rapidly. In neurons with temporally modulated responses, the timing of excitation and inhibition was different in mice and cats. PMID:21865476
Relationship between selected orientation rest frame, circular vection and space motion sickness
NASA Technical Reports Server (NTRS)
Harm, D. L.; Parker, D. E.; Reschke, M. F.; Skinner, N. C.
1998-01-01
Space motion sickness (SMS) and spatial orientation and motion perception disturbances occur in 70-80% of astronauts. People select "rest frames" to create the subjective sense of spatial orientation. In microgravity, the astronaut's rest frame may be based on visual scene polarity cues and on the internal head and body z axis (vertical body axis). The data reported here address the following question: Can an astronaut's orientation rest frame be related and described by other variables including circular vection response latencies and space motion sickness? The astronaut's microgravity spatial orientation rest frames were determined from inflight and postflight verbal reports. Circular vection responses were elicited by rotating a virtual room continuously at 35 degrees/s in pitch, roll and yaw with respect to the astronaut. Latency to the onset of vection was recorded from the time the crew member opened their eyes to the onset of vection. The astronauts who used visual cues exhibited significantly shorter vection latencies than those who used internal z axis cues. A negative binomial regression model was used to represent the observed total SMS symptom scores for each subject for each flight day. Orientation reference type had a significant effect, resulting in an estimated three-fold increase in the expected motion sickness score on flight day 1 for astronauts who used visual cues. The results demonstrate meaningful classification of astronauts' rest frames and their relationships to sensitivity to circular vection and SMS. Thus, it may be possible to use vection latencies to predict SMS severity and duration.
Action-Oriented Population Nutrition Research: High Demand but Limited Supply
Pham, Judy; Pelletier, David
2015-01-01
Background: The relatively rapid ascendancy of nutrition and health on policy agendas, along with greater emphasis on accountability and results, has stimulated interest in new forms of research to guide the development and implementation of effective policies, programs, and interventions—what we refer to as action-oriented research. To date, action-oriented research in the nutrition field is thought to be the exception rather than the rule, but empirical evidence to support this claim is lacking. Methods: We conducted a survey of selected journals in nutrition and public health to assess the extent and nature of population nutrition research published in 2012 that embodied 5 defined characteristics of action-oriented research in relation to: (1) topic(s) of study, (2) processes/influences, (3) actors, (4) methods, and (5) approaches. We identified 762 articles from the 6 selected nutrition journals and 77 nutrition-related articles from the 4 selected public health journals that met our search criteria. Results: Only 7% of the 762 papers in nutrition journals had at least 1 of the 5 action-oriented research characteristics, compared with 36% of the 77 nutrition-related papers in the public health journals. Of all 80 articles that had at least 1 action-oriented research characteristic, only 5 articles (6.25%) embodied all 5 characteristics. Articles with action-oriented research covered a broad range of topics and processes/influences, including policy, workforce development, and schools, as well as actors, such as program staff, store owners, parents, and school staff. In addition, various research methods were used, such as stakeholder analysis, ethnographic narrative, iterative action research, and decision tree modeling, as well as different approaches, including participant-observer and community-based participatory research. Conclusions: Action-oriented research represents a small fraction of articles published in nutrition journals, especially compared with public health journals. This reinforces recent calls to expand population nutrition research agendas to more effectively inform and guide the initiation, development, implementation, and governance of policies, programs, and interventions to address the varied forms of nutrition-related problems. With heightened attention to the magnitude and importance of nutrition problems worldwide, there are substantial reasons and opportunities to incentivize and support such expansion. PMID:26085024
MetroFission: New high-temperature references and sensors for the nuclear industry
NASA Astrophysics Data System (ADS)
Sadli, M.; del Campo, D.; de Podesta, M.; Deuzé, T.; Failleau, G.; Elliott, C. J.; Fourrez, S.; García, C.; Pearce, J. V.
2013-09-01
The European metrology research programme (EMRP) allows funding for metrology-oriented projects in the frame of targeted calls aimed at improving metrology for important contemporary and future needs in different fields such as energy, environment and industry. A joint research project (JRP), called "MetroFission", was selected for funding in the "Energy" call of 2010. This JRP, led by NPL (UK), aims to anticipate and to start addressing the metrological needs of the next generation of nuclear power plants. The need for improving the accuracy and reliability of temperature measurements at temperatures higher than those currently measured in nuclear power plants is dealt with in the first workpackage of the project. This project started in September 2010 and will last for three years. This paper summarizes the activities of the first half of the project and the expected final achievements, which will be essentially oriented towards new temperature references and new devices, adapted to the high temperature range as well as the particularly harsh working conditions.
NASA Astrophysics Data System (ADS)
Shi, Lei; Chu, Zhenyu; Dong, Xueliang; Jin, Wanqin; Dempsey, Eithne
2013-10-01
Highly oriented growth of a hybrid microarray was realized by a facile template-free method on gold substrates for the first time. The proposed formation mechanism involves an interfacial structure-directing force arising from self-assembled monolayers (SAMs) between gold substrates and hybrid crystals. Different SAMs and variable surface coverage of the assembled molecules play a critical role in the interfacial directing forces and influence the morphologies of hybrid films. A highly oriented hybrid microarray was formed on the highly aligned and vertical SAMs of 1,4-benzenedithiol molecules with rigid backbones, which afforded an intense structure-directing power for the oriented growth of hybrid crystals. Additionally, the density of the microarray could be adjusted by controlling the surface coverage of assembled molecules. Based on the hybrid microarray modified electrode with a large specific area (ca. 10 times its geometrical area), a label-free electrochemical DNA biosensor was constructed for the detection of an oligonucleotide fragment of the avian flu virus H5N1. The DNA biosensor displayed a significantly low detection limit of 5 pM (S/N = 3), a wide linear response from 10 pM to 10 nM, as well as excellent selectivity, good regeneration and high stability. We expect that the proposed template-free method can provide a new reference for the fabrication of a highly oriented hybrid array and the as-prepared microarray modified electrode will be a promising paradigm in constructing highly sensitive and selective biosensors.Highly oriented growth of a hybrid microarray was realized by a facile template-free method on gold substrates for the first time. The proposed formation mechanism involves an interfacial structure-directing force arising from self-assembled monolayers (SAMs) between gold substrates and hybrid crystals. Different SAMs and variable surface coverage of the assembled molecules play a critical role in the interfacial directing forces and influence the morphologies of hybrid films. A highly oriented hybrid microarray was formed on the highly aligned and vertical SAMs of 1,4-benzenedithiol molecules with rigid backbones, which afforded an intense structure-directing power for the oriented growth of hybrid crystals. Additionally, the density of the microarray could be adjusted by controlling the surface coverage of assembled molecules. Based on the hybrid microarray modified electrode with a large specific area (ca. 10 times its geometrical area), a label-free electrochemical DNA biosensor was constructed for the detection of an oligonucleotide fragment of the avian flu virus H5N1. The DNA biosensor displayed a significantly low detection limit of 5 pM (S/N = 3), a wide linear response from 10 pM to 10 nM, as well as excellent selectivity, good regeneration and high stability. We expect that the proposed template-free method can provide a new reference for the fabrication of a highly oriented hybrid array and the as-prepared microarray modified electrode will be a promising paradigm in constructing highly sensitive and selective biosensors. Electronic supplementary information (ESI) available: Four-probe method for determining the conductivity of the hybrid crystal (Fig. S1); stability comparisons of the hybrid films (Fig. S2); FESEM images of the hybrid microarray (Fig. S3); electrochemical characterizations of the hybrid films (Fig. S4); DFT simulations (Fig. S5); cross-sectional FESEM image of the hybrid microarray (Fig. S6); regeneration and stability tests of the DNA biosensor (Fig. S7). See DOI: 10.1039/c3nr03097k
Two-axis magnetic field sensor
NASA Technical Reports Server (NTRS)
Smith, Carl H. (Inventor); Nordman, Catherine A. (Inventor); Jander, Albrecht (Inventor); Qian, Zhenghong (Inventor)
2006-01-01
A ferromagnetic thin-film based magnetic field sensor with first and second sensitive direction sensing structures each having a nonmagnetic intermediate layer with two major surfaces on opposite sides thereof having a magnetization reference layer on one and an anisotropic ferromagnetic material sensing layer on the other having a length in a selected length direction and a smaller width perpendicular thereto and parallel to the relatively fixed magnetization direction. The relatively fixed magnetization direction of said magnetization reference layer in each is oriented in substantially parallel to the substrate but substantially perpendicular to that of the other. An annealing process is used to form the desired magnetization directions.
Clinical pharmacy academic career transitions: Viewpoints from the field.
Blackmer, Allison B; Thompson, Angela M; Jeffres, Meghan N; Glode, Ashley E; Thompson, Megan; Mahyari, Nila
2018-02-01
The six authors of this commentary series, who have recently transitioned into or within an academic career, discuss challenging aspects of an academic career change. This is a three-part commentary series that explores select challenges: 1) feedback, evaluation, and advancement; 2) understanding and balancing of distribution of effort; 3) learning how and when to say yes. Faculty, or those interested in pursuing a career in pharmacy academia, can refer to this commentary series as a reference. Schools of pharmacy may utilize this as a tool for new faculty members during orientation in order to ensure smooth integration into the academic environment. Copyright © 2017 Elsevier Inc. All rights reserved.
Construction of the Dependence Matrix Based on the TRIZ Contradiction Matrix in OOD
NASA Astrophysics Data System (ADS)
Ma, Jianhong; Zhang, Quan; Wang, Yanling; Luo, Tao
In the Object-Oriented software design (OOD), design of the class and object, definition of the classes’ interface and inheritance levels and determination of dependent relations have a serious impact on the reusability and flexibility of the system. According to the concrete problems of design, how to select the right solution from the hundreds of the design schemas which has become the focus of attention of designers. After analyzing lots of software design schemas in practice and Object-Oriented design patterns, this paper constructs the dependence matrix of Object-Oriented software design filed, referring to contradiction matrix of TRIZ (Theory of Inventive Problem Solving) proposed by the former Soviet Union innovation master Altshuller. As the practice indicates, it provides a intuitive, common and standardized method for designers to choose the right design schema. Make research and communication more effectively, and also improve the software development efficiency and software quality.
VLBI-based Products - Naval Oceanography Portal
section Advanced Search... Sections Home Time Earth Orientation Astronomy Meteorology Oceanography Ice You terrestrial reference frames and to predict the variable orientation of the Earth in three-dimensional space antennas that define a VLBI-based Terrestrial Reference Frame (TRF) and the Earth Orientation Parameters
Yao, Dezhong
2017-03-01
Currently, average reference is one of the most widely adopted references in EEG and ERP studies. The theoretical assumption is the surface potential integral of a volume conductor being zero, thus the average of scalp potential recordings might be an approximation of the theoretically desired zero reference. However, such a zero integral assumption has been proved only for a spherical surface. In this short communication, three counter-examples are given to show that the potential integral over the surface of a dipole in a volume conductor may not be zero. It depends on the shape of the conductor and the orientation of the dipole. This fact on one side means that average reference is not a theoretical 'gold standard' reference, and on the other side reminds us that the practical accuracy of average reference is not only determined by the well-known electrode array density and its coverage but also intrinsically by the head shape. It means that reference selection still is a fundamental problem to be fixed in various EEG and ERP studies.
Zaltsman, Julia B.; Heimel, J. Alexander
2015-01-01
Classic studies of lateral geniculate nucleus (LGN) and visual cortex (V1) in carnivores and primates have found that a majority of neurons in LGN exhibit a center-surround organization, while V1 neurons exhibit strong orientation selectivity and, in many species, direction selectivity. Recent work in the mouse and the monkey has discovered previously unknown classes of orientation- and direction-selective neurons in LGN. Furthermore, some recent studies in the mouse report that many LGN cells exhibit pronounced orientation biases that are of comparable strength to the subthreshold inputs to V1 neurons. These results raise the possibility that, in rodents, orientation biases of individual LGN cells make a substantial contribution to cortical orientation selectivity. Alternatively, the size and contribution of orientation- or direction-selective channels from LGN to V1 may vary across mammals. To address this question, we examined orientation and direction selectivity in LGN and V1 neurons of a highly visual diurnal rodent: the gray squirrel. In the representation of central vision, only a few LGN neurons exhibited strong orientation or direction selectivity. Across the population, LGN neurons showed weak orientation biases and were much less selective for orientation compared with V1 neurons. Although direction selectivity was weak overall, LGN layers 3abc, which contain neurons that express calbindin, exhibited elevated direction selectivity index values compared with LGN layers 1 and 2. These results suggest that, for central visual fields, the contribution of orientation- and direction-selective channels from the LGN to V1 is small in the squirrel. As in other mammals, this small contribution is elevated in the calbindin-positive layers of the LGN PMID:25717157
Emergence of Orientation Selectivity in the Mammalian Visual Pathway
Scholl, Benjamin; Tan, Andrew Y. Y.; Corey, Joseph
2013-01-01
Orientation selectivity is a property of mammalian primary visual cortex (V1) neurons, yet its emergence along the visual pathway varies across species. In carnivores and primates, elongated receptive fields first appear in V1, whereas in lagomorphs such receptive fields emerge earlier, in the retina. Here we examine the mouse visual pathway and reveal the existence of orientation selectivity in lateral geniculate nucleus (LGN) relay cells. Cortical inactivation does not reduce this orientation selectivity, indicating that cortical feedback is not its source. Orientation selectivity is similar for LGN relay cells spiking and subthreshold input to V1 neurons, suggesting that cortical orientation selectivity is inherited from the LGN in mouse. In contrast, orientation selectivity of cat LGN relay cells is small relative to subthreshold inputs onto V1 simple cells. Together, these differences show that although orientation selectivity exists in visual neurons of both rodents and carnivores, its emergence along the visual pathway, and thus its underlying neuronal circuitry, is fundamentally different. PMID:23804085
Orientation-selective Responses in the Mouse Lateral Geniculate Nucleus
Zhao, Xinyu; Chen, Hui; Liu, Xiaorong
2013-01-01
The dorsal lateral geniculate nucleus (dLGN) receives visual information from the retina and transmits it to the cortex. In this study, we made extracellular recordings in the dLGN of both anesthetized and awake mice, and found that a surprisingly high proportion of cells were selective for stimulus orientation. The orientation selectivity of dLGN cells was unchanged after silencing the visual cortex pharmacologically, indicating that it is not due to cortical feedback. The orientation tuning of some dLGN cells correlated with their elongated receptive fields, while in others orientation selectivity was observed despite the fact that their receptive fields were circular, suggesting that their retinal input might already be orientation selective. Consistently, we revealed orientation/axis-selective ganglion cells in the mouse retina using multielectrode arrays in an in vitro preparation. Furthermore, the orientation tuning of dLGN cells was largely maintained at different stimulus contrasts, which could be sufficiently explained by a simple linear feedforward model. We also compared the degree of orientation selectivity in different visual structures under the same recording condition. Compared with the dLGN, orientation selectivity is greatly improved in the visual cortex, but is similar in the superior colliculus, another major retinal target. Together, our results demonstrate prominent orientation selectivity in the mouse dLGN, which may potentially contribute to visual processing in the cortex. PMID:23904611
The Relation between Gender Role Orientation and Fear and Anxiety in Nonclinic-Referred Children
ERIC Educational Resources Information Center
Muris, Peter; Meesters, Cor; Knoops, Miranda
2005-01-01
This study examined the relation between gender role orientation and fear and anxiety in a sample of nonclinic-referred children (N = 209) ages 10 to 13 years. Children and their parents completed questionnaires assessing children's gender role orientation, toy and activity preferences, and fear and anxiety. Results generally indicated that…
Jackson, Jade; Rich, Anina N; Williams, Mark A; Woolgar, Alexandra
2017-02-01
Human cognition is characterized by astounding flexibility, enabling us to select appropriate information according to the objectives of our current task. A circuit of frontal and parietal brain regions, often referred to as the frontoparietal attention network or multiple-demand (MD) regions, are believed to play a fundamental role in this flexibility. There is evidence that these regions dynamically adjust their responses to selectively process information that is currently relevant for behavior, as proposed by the "adaptive coding hypothesis" [Duncan, J. An adaptive coding model of neural function in prefrontal cortex. Nature Reviews Neuroscience, 2, 820-829, 2001]. Could this provide a neural mechanism for feature-selective attention, the process by which we preferentially process one feature of a stimulus over another? We used multivariate pattern analysis of fMRI data during a perceptually challenging categorization task to investigate whether the representation of visual object features in the MD regions flexibly adjusts according to task relevance. Participants were trained to categorize visually similar novel objects along two orthogonal stimulus dimensions (length/orientation) and performed short alternating blocks in which only one of these dimensions was relevant. We found that multivoxel patterns of activation in the MD regions encoded the task-relevant distinctions more strongly than the task-irrelevant distinctions: The MD regions discriminated between stimuli of different lengths when length was relevant and between the same objects according to orientation when orientation was relevant. The data suggest a flexible neural system that adjusts its representation of visual objects to preferentially encode stimulus features that are currently relevant for behavior, providing a neural mechanism for feature-selective attention.
Mental health reform at a systems level: widening the lens on recovery-oriented care.
Kidd, Sean A; Mckenzie, Kwame J; Virdee, Gursharan
2014-05-01
This paper is an initial attempt to collate the literature on psychiatric inpatient recovery-based care and, more broadly, to situate the inpatient care sector within a mental health reform dialogue that, to date, has focused almost exclusively on outpatient and community practices. We make the argument that until an evidence base is developed for recovery-oriented practices on hospital wards, the effort to advance recovery-oriented systems will stagnate. Our scoping review was conducted in line with the 2009 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (commonly referred to as PRISMA) guidelines. Among the 27 papers selected for review, most were descriptive or uncontrolled outcome studies. Studies addressing strategies for improving care quality provide some modest evidence for reflective dialogue with former inpatient clients, role play and mentorship, and pairing general training in recovery oriented care with training in specific interventions, such as Illness Management and Recovery. Relative to some other fields of medicine, evidence surrounding the question of recovery-oriented care on psychiatric wards and how it may be implemented is underdeveloped. Attention to mental health reform in hospitals is critical to the emergence of recovery-oriented systems of care and the realization of the mandate set forward in the Mental Health Strategy for Canada.
The Representation of Orientation in Macaque V2: Four Stripes Not Three
Felleman, Daniel J.; Lim, Heejin; Xiao, Youping; Wang, Yi; Eriksson, Anastasia; Parajuli, Arun
2015-01-01
Area V2 of macaque monkeys is traditionally thought to consist of 3 distinct functional compartments with characteristic cortical connections and functional properties. Orientation selectivity is one property that has frequently been used to distinguish V2 stripes, however, this receptive field property has been found in a high percentage of neurons across V2 compartments. Using quantitative intrinsic cortical imaging, we derived maps of preferred orientation, orientation selectivity, and orientation gradient in thin stripes, thick stripes, and interstripes in area V2. Orientation-selective responses were found in each V2 stripe, but the magnitude and organization of orientation selectivity differed significantly from stripe to stripe. Remarkably, the 2 pale stripes flanking each cytochrome oxidase dense stripe differed significantly in their representation of orientation resulting in their distinction as type-I and type-II interstripes. V2 orientation maps are characterized by clockwise and anticlockwise “orientation pinwheels”, but unlike V1, they are not homogeneously distributed across V2. Furthermore, V2 stripes contain large-scale sequences of preferred orientation. These analyses demonstrate that V2 consists of 4 distinct functional compartments; thick stripes and type-II interstripes, which are strongly orientation selective and thin stripes and type-I interstripes, which are significantly less selective for orientation and exhibit larger orientation gradient magnitudes. PMID:24614951
Blackmer, Allison B; Thompson, Angela M; Jeffres, Meghan N; Glode, Ashley E; Mahyari, Nila; Thompson, Megan
2018-02-01
The six authors of this commentary series, who have recently transitioned into or within an academic career, discuss challenging aspects of an academic career change. This is a three-part commentary series that explores select challenges: 1) feedback, evaluation and advancement; 2) understanding and balancing of distribution of effort; 3) learning how and when to say yes. Faculty, or those interested in pursuing a career in pharmacy academia, can refer to this commentary series as a reference. Schools of pharmacy may utilize this as a tool for new faculty members during orientation in order to ensure smooth integration into the academic environment. Copyright © 2017 Elsevier Inc. All rights reserved.
Left and right brain-oriented hemisity subjects show opposite behavioral preferences.
Morton, Bruce E
2012-01-01
Recently, three independent, intercorrelated biophysical measures have provided the first quantitative measures of a binary form of behavioral laterality called "Hemisity," a term referring to inherent opposite right or left brain-oriented differences in thinking and behavioral styles. Crucially, the right or left brain-orientation of individuals assessed by these methods was later found to be essentially congruent with the thicker side of their ventral gyrus of the anterior cingulate cortex (vgACC) as revealed by a 3 min MRI procedure. Laterality of this putative executive structural element has thus become the primary standard defining individual hemisity. Here, the behavior of 150 subjects, whose hemisity had been calibrated by MRI, was assessed using five MRI-calibrated preference questionnaires, two of which were new. Right and left brain-oriented subjects selected opposite answers (p > 0.05) for 47 of the 107 "either-or," forced choice type preference questionnaire items. The resulting 30 hemisity subtype preference differences were present in several areas. These were: (1) in logical orientation, (2) in type of consciousness, (3) in fear level and sensitivity, (4) in social-professional orientation, and (5) in pair bonding-spousal dominance style. The right and left brain-oriented hemisity subtype subjects, sorted on the anatomical basis of upon which brain side their vgACC was thickest, showed 30 significant differences in their "either-or" type of behavioral preferences.
NASA Astrophysics Data System (ADS)
Tafforin, Carole
Weightlessness in man induces changes in astronaut orientations and consequently in his patterns of movements and postures. An ethological method has been used to describe the "overall" spontaneous behaviour of astronauts as seen from video recordings made during Space Flights. The work has consisted in analysing the relationships between orientation, movement and posture as an indication of a motor adaptative reorganization in such a situation. The results obtained lead us to consider three different aspects: (1) Orientation references. The astronaut orientates himself with reference to the Space Shuttle's internal structure; the increase of visual activity confirms the choice of the retinal vertical as frame of reference. (2) Motor coordination. The main data reveals a decrease in motor stereotypies by the diversity of motor acts observed and the importance of the link between orientation and posture described as follows: slightly inclined forward position, with legs flexed at about 135°. (3) Cognitive references. There appears to be a new organization of the cognitive image of the body scheme, the missing vestibular information being supplied by peripheral vision instead which could play a role in the astronaut's perception of his own movement.
Origin and Function of Tuning Diversity in Macaque Visual Cortex
Goris, Robbe L.T.; Simoncelli, Eero P.; Movshon, J. Anthony
2016-01-01
SUMMARY Neurons in visual cortex vary in their orientation selectivity. We measured responses of V1 and V2 cells to orientation mixtures and fit them with a model whose stimulus selectivity arises from the combined effects of filtering, suppression, and response nonlinearity. The model explains the diversity of orientation selectivity with neuron-to-neuron variability in all three mechanisms, of which variability in the orientation bandwidth of linear filtering is the most important. The model also accounts for the cells’ diversity of spatial frequency selectivity. Tuning diversity is matched to the needs of visual encoding. The orientation content found in natural scenes is diverse, and neurons with different selectivities are adapted to different stimulus configurations. Single orientations are better encoded by highly selective neurons, while orientation mixtures are better encoded by less selective neurons. A diverse population of neurons therefore provides better overall discrimination capabilities for natural images than any homogeneous population. PMID:26549331
Robust Vision-Based Pose Estimation Algorithm for AN Uav with Known Gravity Vector
NASA Astrophysics Data System (ADS)
Kniaz, V. V.
2016-06-01
Accurate estimation of camera external orientation with respect to a known object is one of the central problems in photogrammetry and computer vision. In recent years this problem is gaining an increasing attention in the field of UAV autonomous flight. Such application requires a real-time performance and robustness of the external orientation estimation algorithm. The accuracy of the solution is strongly dependent on the number of reference points visible on the given image. The problem only has an analytical solution if 3 or more reference points are visible. However, in limited visibility conditions it is often needed to perform external orientation with only 2 visible reference points. In such case the solution could be found if the gravity vector direction in the camera coordinate system is known. A number of algorithms for external orientation estimation for the case of 2 known reference points and a gravity vector were developed to date. Most of these algorithms provide analytical solution in the form of polynomial equation that is subject to large errors in the case of complex reference points configurations. This paper is focused on the development of a new computationally effective and robust algorithm for external orientation based on positions of 2 known reference points and a gravity vector. The algorithm implementation for guidance of a Parrot AR.Drone 2.0 micro-UAV is discussed. The experimental evaluation of the algorithm proved its computational efficiency and robustness against errors in reference points positions and complex configurations.
Incremental Upgrade of Legacy Systems (IULS)
2001-04-01
analysis task employed SEI’s Feature-Oriented Domain Analysis methodology (see FODA reference) and included several phases: • Context Analysis • Establish...Legacy, new Host and upgrade system and software. The Feature Oriented Domain Analysis approach ( FODA , see SUM References) was used for this step...Feature-Oriented Domain Analysis ( FODA ) Feasibility Study (CMU/SEI-90-TR- 21, ESD-90-TR-222); Software Engineering Institute, Carnegie Mellon University
Pfleger, B; Bonds, A B
1995-01-01
The influence of GABAA receptors on orientation selectivity of cat complex cells was tested by iontophoresis of the GABAA receptor blockers bicuculline and N-methyl-bicuculline while stimulating with drifting sinusoidal gratings. Reduction of orientation tuning was markedly less than reported in previous studies that used drifting bars as visual stimuli. Only 3/31 cells lost orientation selectivity, with an average increase in bandwidth of 33%, as opposed to half the cells losing selectivity and a bandwidth increase for the remainder of 47% as reported previously. Infusion of GABAA blockers revealed a prominent stimulus onset transient response, lasting about 120 ms, that showed a broadening of orientation selectivity comparable to that found using drifting bars under similar circumstances. We believe that drifting gratings emphasize a steady-state response component that retains, in the presence of GABAA blockers, significant orientation selectivity. Because the onset transient is initially unselective for orientation, we suggest that the steady-state, orientation-selective response component develops from an alternate inhibitory mechanism, possibly mediated by GABAB receptors.
Quantitative susceptibility mapping: Report from the 2016 reconstruction challenge.
Langkammer, Christian; Schweser, Ferdinand; Shmueli, Karin; Kames, Christian; Li, Xu; Guo, Li; Milovic, Carlos; Kim, Jinsuh; Wei, Hongjiang; Bredies, Kristian; Buch, Sagar; Guo, Yihao; Liu, Zhe; Meineke, Jakob; Rauscher, Alexander; Marques, José P; Bilgic, Berkin
2018-03-01
The aim of the 2016 quantitative susceptibility mapping (QSM) reconstruction challenge was to test the ability of various QSM algorithms to recover the underlying susceptibility from phase data faithfully. Gradient-echo images of a healthy volunteer acquired at 3T in a single orientation with 1.06 mm isotropic resolution. A reference susceptibility map was provided, which was computed using the susceptibility tensor imaging algorithm on data acquired at 12 head orientations. Susceptibility maps calculated from the single orientation data were compared against the reference susceptibility map. Deviations were quantified using the following metrics: root mean squared error (RMSE), structure similarity index (SSIM), high-frequency error norm (HFEN), and the error in selected white and gray matter regions. Twenty-seven submissions were evaluated. Most of the best scoring approaches estimated the spatial frequency content in the ill-conditioned domain of the dipole kernel using compressed sensing strategies. The top 10 maps in each category had similar error metrics but substantially different visual appearance. Because QSM algorithms were optimized to minimize error metrics, the resulting susceptibility maps suffered from over-smoothing and conspicuity loss in fine features such as vessels. As such, the challenge highlighted the need for better numerical image quality criteria. Magn Reson Med 79:1661-1673, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.
Origin and Function of Tuning Diversity in Macaque Visual Cortex.
Goris, Robbe L T; Simoncelli, Eero P; Movshon, J Anthony
2015-11-18
Neurons in visual cortex vary in their orientation selectivity. We measured responses of V1 and V2 cells to orientation mixtures and fit them with a model whose stimulus selectivity arises from the combined effects of filtering, suppression, and response nonlinearity. The model explains the diversity of orientation selectivity with neuron-to-neuron variability in all three mechanisms, of which variability in the orientation bandwidth of linear filtering is the most important. The model also accounts for the cells' diversity of spatial frequency selectivity. Tuning diversity is matched to the needs of visual encoding. The orientation content found in natural scenes is diverse, and neurons with different selectivities are adapted to different stimulus configurations. Single orientations are better encoded by highly selective neurons, while orientation mixtures are better encoded by less selective neurons. A diverse population of neurons therefore provides better overall discrimination capabilities for natural images than any homogeneous population. Copyright © 2015 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Wang, Jian; Meng, Xiaohong; Zheng, Wanqiu
2017-10-01
The elastic-wave reverse-time migration of inhomogeneous anisotropic media is becoming the hotspot of research today. In order to ensure the accuracy of the migration, it is necessary to separate the wave mode into P-wave and S-wave before migration. For inhomogeneous media, the Kelvin-Christoffel equation can be solved in the wave-number domain by using the anisotropic parameters of the mesh nodes, and the polarization vector of the P-wave and S-wave at each node can be calculated and transformed into the space domain to obtain the quasi-differential operators. However, this method is computationally expensive, especially for the process of quasi-differential operators. In order to reduce the computational complexity, the wave-mode separation of mixed domain can be realized on the basis of a reference model in the wave-number domain. But conventional interpolation methods and reference model selection methods reduce the separation accuracy. In order to further improve the separation effect, this paper introduces an inverse-distance interpolation method involving position shading and uses the reference model selection method of random points scheme. This method adds the spatial weight coefficient K, which reflects the orientation of the reference point on the conventional IDW algorithm, and the interpolation process takes into account the combined effects of the distance and azimuth of the reference points. Numerical simulation shows that the proposed method can separate the wave mode more accurately using fewer reference models and has better practical value.
Synaptic Mechanisms Generating Orientation Selectivity in the ON Pathway of the Rabbit Retina
Venkataramani, Sowmya
2016-01-01
Neurons that signal the orientation of edges within the visual field have been widely studied in primary visual cortex. Much less is known about the mechanisms of orientation selectivity that arise earlier in the visual stream. Here we examine the synaptic and morphological properties of a subtype of orientation-selective ganglion cell in the rabbit retina. The receptive field has an excitatory ON center, flanked by excitatory OFF regions, a structure similar to simple cell receptive fields in primary visual cortex. Examination of the light-evoked postsynaptic currents in these ON-type orientation-selective ganglion cells (ON-OSGCs) reveals that synaptic input is mediated almost exclusively through the ON pathway. Orientation selectivity is generated by larger excitation for preferred relative to orthogonal stimuli, and conversely larger inhibition for orthogonal relative to preferred stimuli. Excitatory orientation selectivity arises in part from the morphology of the dendritic arbors. Blocking GABAA receptors reduces orientation selectivity of the inhibitory synaptic inputs and the spiking responses. Negative contrast stimuli in the flanking regions produce orientation-selective excitation in part by disinhibition of a tonic NMDA receptor-mediated input arising from ON bipolar cells. Comparison with earlier studies of OFF-type OSGCs indicates that diverse synaptic circuits have evolved in the retina to detect the orientation of edges in the visual input. SIGNIFICANCE STATEMENT A core goal for visual neuroscientists is to understand how neural circuits at each stage of the visual system extract and encode features from the visual scene. This study documents a novel type of orientation-selective ganglion cell in the retina and shows that the receptive field structure is remarkably similar to that of simple cells in primary visual cortex. However, the data indicate that, unlike in the cortex, orientation selectivity in the retina depends on the activity of inhibitory interneurons. The results further reveal the physiological basis for feature detection in the visual system, elucidate the synaptic mechanisms that generate orientation selectivity at an early stage of visual processing, and illustrate a novel role for NMDA receptors in retinal processing. PMID:26985041
Synaptic Mechanisms Generating Orientation Selectivity in the ON Pathway of the Rabbit Retina.
Venkataramani, Sowmya; Taylor, W Rowland
2016-03-16
Neurons that signal the orientation of edges within the visual field have been widely studied in primary visual cortex. Much less is known about the mechanisms of orientation selectivity that arise earlier in the visual stream. Here we examine the synaptic and morphological properties of a subtype of orientation-selective ganglion cell in the rabbit retina. The receptive field has an excitatory ON center, flanked by excitatory OFF regions, a structure similar to simple cell receptive fields in primary visual cortex. Examination of the light-evoked postsynaptic currents in these ON-type orientation-selective ganglion cells (ON-OSGCs) reveals that synaptic input is mediated almost exclusively through the ON pathway. Orientation selectivity is generated by larger excitation for preferred relative to orthogonal stimuli, and conversely larger inhibition for orthogonal relative to preferred stimuli. Excitatory orientation selectivity arises in part from the morphology of the dendritic arbors. Blocking GABAA receptors reduces orientation selectivity of the inhibitory synaptic inputs and the spiking responses. Negative contrast stimuli in the flanking regions produce orientation-selective excitation in part by disinhibition of a tonic NMDA receptor-mediated input arising from ON bipolar cells. Comparison with earlier studies of OFF-type OSGCs indicates that diverse synaptic circuits have evolved in the retina to detect the orientation of edges in the visual input. A core goal for visual neuroscientists is to understand how neural circuits at each stage of the visual system extract and encode features from the visual scene. This study documents a novel type of orientation-selective ganglion cell in the retina and shows that the receptive field structure is remarkably similar to that of simple cells in primary visual cortex. However, the data indicate that, unlike in the cortex, orientation selectivity in the retina depends on the activity of inhibitory interneurons. The results further reveal the physiological basis for feature detection in the visual system, elucidate the synaptic mechanisms that generate orientation selectivity at an early stage of visual processing, and illustrate a novel role for NMDA receptors in retinal processing. Copyright © 2016 the authors 0270-6474/16/363336-14$15.00/0.
Instructionism and Constructivism: Reconciling Two Very Good Ideas
ERIC Educational Resources Information Center
Johnson, Genevieve Marie
2009-01-01
Instructionism refers to educational practices that are teacher-focused, skill-based, product-oriented, non-interactive, and highly prescribed. Constructivism refers to educational practices that are student-focused, meaning-based, process-oriented, interactive, and responsive to student interest. There is disagreement regarding which curricular…
Mao, Xinrui; Tian, Mengxi; Liu, Yi; Li, Bingcan; Jin, Yan; Wu, Yanhong; Guo, Chunyan
2017-01-01
Retrieval inhibition hypothesis of directed forgetting effects assumed TBF (to-be-forgotten) items were not retrieved intentionally, while selective rehearsal hypothesis assumed the memory representation of retrieved TBF (to-be-forgotten) items was weaker than TBR (to-be-remembered) items. Previous studies indicated that directed forgetting effects of item-cueing method resulted from selective rehearsal at encoding, but the mechanism of retrieval inhibition that affected directed forgetting of TBF (to-be-forgotten) items was not clear. Strategic retrieval is a control process allowing the selective retrieval of target information, which includes retrieval orientation and strategic recollection. Retrieval orientation via the comparison of tasks refers to the specific form of processing resulted by retrieval efforts. Strategic recollection is the type of strategies to recollect studied items for the retrieval success of targets. Using a "directed forgetting" paradigm combined with a memory exclusion task, our investigation of strategic retrieval in directed forgetting assisted to explore how retrieval inhibition played a role on directed forgetting effects. When TBF items were targeted, retrieval orientation showed more positive ERPs to new items, indicating that TBF items demanded more retrieval efforts. The results of strategic recollection indicated that: (a) when TBR items were retrieval targets, late parietal old/new effects were only evoked by TBR items but not TBF items, indicating the retrieval inhibition of TBF items; (b) when TBF items were retrieval targets, the late parietal old/new effect were evoked by both TBR items and TBF items, indicating that strategic retrieval could overcome retrieval inhibition of TBF items. These findings suggested the modulation of strategic retrieval on retrieval inhibition of directed forgetting, supporting that directed forgetting effects were not only caused by selective rehearsal, but also retrieval inhibition.
Mao, Xinrui; Tian, Mengxi; Liu, Yi; Li, Bingcan; Jin, Yan; Wu, Yanhong; Guo, Chunyan
2017-01-01
Retrieval inhibition hypothesis of directed forgetting effects assumed TBF (to-be-forgotten) items were not retrieved intentionally, while selective rehearsal hypothesis assumed the memory representation of retrieved TBF (to-be-forgotten) items was weaker than TBR (to-be-remembered) items. Previous studies indicated that directed forgetting effects of item-cueing method resulted from selective rehearsal at encoding, but the mechanism of retrieval inhibition that affected directed forgetting of TBF (to-be-forgotten) items was not clear. Strategic retrieval is a control process allowing the selective retrieval of target information, which includes retrieval orientation and strategic recollection. Retrieval orientation via the comparison of tasks refers to the specific form of processing resulted by retrieval efforts. Strategic recollection is the type of strategies to recollect studied items for the retrieval success of targets. Using a “directed forgetting” paradigm combined with a memory exclusion task, our investigation of strategic retrieval in directed forgetting assisted to explore how retrieval inhibition played a role on directed forgetting effects. When TBF items were targeted, retrieval orientation showed more positive ERPs to new items, indicating that TBF items demanded more retrieval efforts. The results of strategic recollection indicated that: (a) when TBR items were retrieval targets, late parietal old/new effects were only evoked by TBR items but not TBF items, indicating the retrieval inhibition of TBF items; (b) when TBF items were retrieval targets, the late parietal old/new effect were evoked by both TBR items and TBF items, indicating that strategic retrieval could overcome retrieval inhibition of TBF items. These findings suggested the modulation of strategic retrieval on retrieval inhibition of directed forgetting, supporting that directed forgetting effects were not only caused by selective rehearsal, but also retrieval inhibition. PMID:28900411
Relative azimuth inversion by way of damped maximum correlation estimates
Ringler, A.T.; Edwards, J.D.; Hutt, C.R.; Shelly, F.
2012-01-01
Horizontal seismic data are utilized in a large number of Earth studies. Such work depends on the published orientations of the sensitive axes of seismic sensors relative to true North. These orientations can be estimated using a number of different techniques: SensOrLoc (Sensitivity, Orientation and Location), comparison to synthetics (Ekstrom and Busby, 2008), or by way of magnetic compass. Current methods for finding relative station azimuths are unable to do so with arbitrary precision quickly because of limitations in the algorithms (e.g. grid search methods). Furthermore, in order to determine instrument orientations during station visits, it is critical that any analysis software be easily run on a large number of different computer platforms and the results be obtained quickly while on site. We developed a new technique for estimating relative sensor azimuths by inverting for the orientation with the maximum correlation to a reference instrument, using a non-linear parameter estimation routine. By making use of overlapping windows, we are able to make multiple azimuth estimates, which helps to identify the confidence of our azimuth estimate, even when the signal-to-noise ratio (SNR) is low. Finally, our algorithm has been written as a stand-alone, platform independent, Java software package with a graphical user interface for reading and selecting data segments to be analyzed.
CAR: contig assembly of prokaryotic draft genomes using rearrangements.
Lu, Chin Lung; Chen, Kun-Tze; Huang, Shih-Yuan; Chiu, Hsien-Tai
2014-11-28
Next generation sequencing technology has allowed efficient production of draft genomes for many organisms of interest. However, most draft genomes are just collections of independent contigs, whose relative positions and orientations along the genome being sequenced are unknown. Although several tools have been developed to order and orient the contigs of draft genomes, more accurate tools are still needed. In this study, we present a novel reference-based contig assembly (or scaffolding) tool, named as CAR, that can efficiently and more accurately order and orient the contigs of a prokaryotic draft genome based on a reference genome of a related organism. Given a set of contigs in multi-FASTA format and a reference genome in FASTA format, CAR can output a list of scaffolds, each of which is a set of ordered and oriented contigs. For validation, we have tested CAR on a real dataset composed of several prokaryotic genomes and also compared its performance with several other reference-based contig assembly tools. Consequently, our experimental results have shown that CAR indeed performs better than all these other reference-based contig assembly tools in terms of sensitivity, precision and genome coverage. CAR serves as an efficient tool that can more accurately order and orient the contigs of a prokaryotic draft genome based on a reference genome. The web server of CAR is freely available at http://genome.cs.nthu.edu.tw/CAR/ and its stand-alone program can also be downloaded from the same website.
Higgins, Sean W; Spratley, E Meade; Boe, Richard A; Hayes, Curtis W; Jiranek, William A; Wayne, Jennifer S
2014-11-05
The inherently complex three-dimensional morphology of both the pelvis and acetabulum create difficulties in accurately determining acetabular orientation. Our objectives were to develop a reliable and accurate methodology for determining three-dimensional acetabular orientation and to utilize it to describe relevant characteristics of a large population of subjects without apparent hip pathology. High-resolution computed tomography studies of 200 patients previously receiving pelvic scans for indications not related to orthopaedic conditions were selected from our institution's database. Three-dimensional models of each osseous pelvis were generated to extract specific anatomical data sets. A novel computational method was developed to determine standard measures of three-dimensional acetabular orientation within an automatically identified anterior pelvic plane reference frame. Automatically selected points on the osseous ridge of the acetabulum were used to generate a best-fit plane for describing acetabular orientation. Our method showed excellent interobserver and intraobserver agreement (an intraclass correlation coefficient [ICC] of >0.999) and achieved high levels of accuracy. A significant difference between males and females in both anteversion (average, 3.5°; 95% confidence interval [CI], 1.9° to 5.1° across all angular definitions; p < 0.0001) and inclination (1.4°; 95% CI, 0.6° to 2.3° for anatomic angular definition; p < 0.002) was observed. Intrapatient asymmetry in anatomic measures showed bilateral differences in anteversion (maximum, 12.1°) and in inclination (maximum, 10.9°). Significant differences in acetabular orientation between the sexes can be detected only with accurate measurements that account for the entire acetabulum. While a wide range of interpatient acetabular orientations was observed, the majority of subjects had acetabula that were relatively symmetrical in both inclination and anteversion. A highly accurate and reproducible method for determining the orientation of the acetabulum's aperture will benefit both surgeons and patients, by further refining the distinctions between normal and abnormal hip characteristics. Enhanced understanding of the acetabulum could be useful in the diagnostic, planning, and execution stages for surgical procedures of the hip or in advancing the design of new implant systems. Copyright © 2014 by The Journal of Bone and Joint Surgery, Incorporated.
Xue, Guobiao; Zhao, Xikang; Qu, Ge; Xu, Tianbai; Gumyusenge, Aristide; Zhang, Zhuorui; Zhao, Yan; Diao, Ying; Li, Hanying; Mei, Jianguo
2017-08-02
The selection of side chains is important in design of conjugated polymers. It not only affects their intrinsic physical properties, but also has an impact on thin film morphologies. Recent reports suggested that a face-on/edge-on bimodal orientation observed in polymer thin films may be responsible for a three-dimensional (3D) charge transport and leads to dramatically improved mobility in donor-acceptor based conjugated polymers. To achieve a bimodal orientation in thin films has been seldom explored from the aspect of molecular design. Here, we demonstrate a design strategy involving the use of asymmetric side chains that enables an isoindigo-based polymer to adopt a distinct bimodal orientation, confirmed by the grazing incidence X-ray diffraction. As a result, the polymer presents an average high mobility of 3.8 ± 0.7 cm 2 V -1 s -1 with a maximum value of 5.1 cm 2 V -1 s -1 , in comparison with 0.47 and 0.51 cm 2 V -1 s -1 obtained from the two reference polymers. This study exemplifies a new strategy to develop the next generation polymers through understanding the property-structure relationship.
Orientation selectivity in the visual cortex of the nine-banded armadillo
Scholl, Benjamin; Rylee, Johnathan; Luci, Jeffrey J.; Priebe, Nicholas J.
2017-01-01
Orientation selectivity in primary visual cortex (V1) has been proposed to reflect a canonical computation performed by the neocortical circuitry. Although orientation selectivity has been reported in all mammals examined to date, the degree of selectivity and the functional organization of selectivity vary across mammalian clades. The differences in degree of orientation selectivity are large, from reports in marsupials that only a small subset of neurons are selective to studies in carnivores, in which it is rare to find a neuron lacking selectivity. Furthermore, the functional organization in cortex varies in that the primate and carnivore V1 is characterized by an organization in which nearby neurons share orientation preference while other mammals such as rodents and lagomorphs either lack or have only extremely weak clustering. To gain insight into the evolutionary emergence of orientation selectivity, we examined the nine-banded armadillo, a species within the early placental clade Xenarthra. Here we use a combination of neuroimaging, histological, and electrophysiological methods to identify the retinofugal pathways, locate V1, and for the first time examine the functional properties of V1 neurons in the armadillo (Dasypus novemcinctus) V1. Individual neurons were strongly sensitive to the orientation and often the direction of drifting gratings. We uncovered a wide range of orientation preferences but found a bias for horizontal gratings. The presence of strong orientation selectivity in armadillos suggests that the circuitry responsible for this computation is common to all placental mammals. NEW & NOTEWORTHY The current study shows that armadillo primary visual cortex (V1) neurons share the signature properties of V1 neurons of primates, carnivorans, and rodents. Furthermore, these neurons exhibit a degree of selectivity for stimulus orientation and motion direction similar to that found in primate V1. Our findings in armadillo visual cortex suggest that the functional properties of V1 neurons emerged early in the mammalian lineage, near the time of the divergence of marsupials. PMID:28053246
Effects of visual information regarding allocentric processing in haptic parallelity matching.
Van Mier, Hanneke I
2013-10-01
Research has revealed that haptic perception of parallelity deviates from physical reality. Large and systematic deviations have been found in haptic parallelity matching most likely due to the influence of the hand-centered egocentric reference frame. Providing information that increases the influence of allocentric processing has been shown to improve performance on haptic matching. In this study allocentric processing was stimulated by providing informative vision in haptic matching tasks that were performed using hand- and arm-centered reference frames. Twenty blindfolded participants (ten men, ten women) explored the orientation of a reference bar with the non-dominant hand and subsequently matched (task HP) or mirrored (task HM) its orientation on a test bar with the dominant hand. Visual information was provided by means of informative vision with participants having full view of the test bar, while the reference bar was blocked from their view (task VHP). To decrease the egocentric bias of the hands, participants also performed a visual haptic parallelity drawing task (task VHPD) using an arm-centered reference frame, by drawing the orientation of the reference bar. In all tasks, the distance between and orientation of the bars were manipulated. A significant effect of task was found; performance improved from task HP, to VHP to VHPD, and HM. Significant effects of distance were found in the first three tasks, whereas orientation and gender effects were only significant in tasks HP and VHP. The results showed that stimulating allocentric processing by means of informative vision and reducing the egocentric bias by using an arm-centered reference frame led to most accurate performance on parallelity matching. © 2013 Elsevier B.V. All rights reserved.
Action-Oriented Population Nutrition Research: High Demand but Limited Supply.
Pham, Judy; Pelletier, David
2015-05-27
The relatively rapid ascendancy of nutrition and health on policy agendas, along with greater emphasis on accountability and results, has stimulated interest in new forms of research to guide the development and implementation of effective policies, programs, and interventions-what we refer to as action-oriented research. To date, action-oriented research in the nutrition field is thought to be the exception rather than the rule, but empirical evidence to support this claim is lacking. We conducted a survey of selected journals in nutrition and public health to assess the extent and nature of population nutrition research published in 2012 that embodied 5 defined characteristics of action-oriented research in relation to: (1) topic(s) of study, (2) processes/influences, (3) actors, (4) methods, and (5) approaches. We identified 762 articles from the 6 selected nutrition journals and 77 nutrition-related articles from the 4 selected public health journals that met our search criteria. Only 7% of the 762 papers in nutrition journals had at least 1 of the 5 action-oriented research characteristics, compared with 36% of the 77 nutrition-related papers in the public health journals. Of all 80 articles that had at least 1 action-oriented research characteristic, only 5 articles (6.25%) embodied all 5 characteristics. Articles with action-oriented research covered a broad range of topics and processes/influences, including policy, workforce development, and schools, as well as actors, such as program staff, store owners, parents, and school staff. In addition, various research methods were used, such as stakeholder analysis, ethnographic narrative, iterative action research, and decision tree modeling, as well as different approaches, including participant-observer and community-based participatory research. Action-oriented research represents a small fraction of articles published in nutrition journals, especially compared with public health journals. This reinforces recent calls to expand population nutrition research agendas to more effectively inform and guide the initiation, development, implementation, and governance of policies, programs, and interventions to address the varied forms of nutrition-related problems. With heightened attention to the magnitude and importance of nutrition problems worldwide, there are substantial reasons and opportunities to incentivize and support such expansion. © Pham et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly cited. To view a copy of the license, visit http://creativecommons.org/licenses/by/3.0/
The effect of implied orientation derived from verbal context on picture recognition.
Stanfield, R A; Zwaan, R A
2001-03-01
Perceptual symbol systems assume an analogue relationship between a symbol and its referent, whereas amodal symbol systems assume an arbitrary relationship between a symbol and its referent. According to perceptual symbol theories, the complete representation of an object, called a simulation, should reflect physical characteristics of the object. Amodal theories, in contrast, do not make this prediction. We tested the hypothesis, derived from perceptual symbol theories, that people mentally represent the orientation of an object implied by a verbal description. Orientation (vertical-horizontal) was manipulated by having participants read a sentence that implicitly suggested a particular orientation for an object. Then recognition latencies to pictures of the object in each of the two orientations were measured. Pictures matching the orientation of the object implied by the sentence were responded to faster than pictures that did not match the orientation. This finding is interpreted as offering support for theories positing perceptual symbol systems.
Al-Janabi, Shahd; Greenberg, Adam S
2016-10-01
The representational basis of attentional selection can be object-based. Various studies have suggested, however, that object-based selection is less robust than spatial selection across experimental paradigms. We sought to examine the manner by which the following factors might explain this variation: Target-Object Integration (targets 'on' vs. part 'of' an object), Attention Distribution (narrow vs. wide), and Object Orientation (horizontal vs. vertical). In Experiment 1, participants discriminated between two targets presented 'on' an object in one session, or presented as a change 'of' an object in another session. There was no spatial cue-thus, attention was initially focused widely-and the objects were horizontal or vertical. We found evidence of object-based selection only when targets constituted a change 'of' an object. Additionally, object orientation modulated the sign of object-based selection: We observed a same-object advantage for horizontal objects, but a same-object cost for vertical objects. In Experiment 2, an informative cue preceded a single target presented 'on' an object or as a change 'of' an object (thus, attention was initially focused narrowly). Unlike in Experiment 1, we found evidence of object-based selection independent of target-object integration. We again found that the sign of selection was modulated by the objects' orientation. This result may reflect a meridian effect, which emerged due to anisotropies in the cortical representations when attention is oriented endogenously. Experiment 3 revealed that object orientation did not modulate object-based selection when attention was oriented exogenously. Our findings suggest that target-object integration, attention distribution, and object orientation modulate object-based selection, but only in combination.
Development of cortical orientation selectivity in the absence of visual experience with contour
Hussain, Shaista; Weliky, Michael
2011-01-01
Visual cortical neurons are selective for the orientation of lines, and the full development of this selectivity requires natural visual experience after eye opening. Here we examined whether this selectivity develops without seeing lines and contours. Juvenile ferrets were reared in a dark room and visually trained by being shown a movie of flickering, sparse spots. We found that despite the lack of contour visual experience, the cortical neurons of these ferrets developed strong orientation selectivity and exhibited simple-cell receptive fields. This finding suggests that overt contour visual experience is unnecessary for the maturation of orientation selectivity and is inconsistent with the computational models that crucially require the visual inputs of lines and contours for the development of orientation selectivity. We propose that a correlation-based model supplemented with a constraint on synaptic strength dynamics is able to account for our experimental result. PMID:21753023
Figueroa Velez, Dario X.; Ellefsen, Kyle L.; Hathaway, Ethan R.; Carathedathu, Mathew C.
2017-01-01
The maturation of cortical parvalbumin-positive (PV) interneurons depends on the interaction of innate and experience-dependent factors. Dark-rearing experiments suggest that visual experience determines when broad orientation selectivity emerges in visual cortical PV interneurons. Here, using neural transplantation and in vivo calcium imaging of mouse visual cortex, we investigated whether innate mechanisms contribute to the maturation of orientation selectivity in PV interneurons. First, we confirmed earlier findings showing that broad orientation selectivity emerges in PV interneurons by 2 weeks after vision onset, ∼35 d after these cells are born. Next, we assessed the functional development of transplanted PV (tPV) interneurons. Surprisingly, 25 d after transplantation (DAT) and >2 weeks after vision onset, we found that tPV interneurons have not developed broad orientation selectivity. By 35 DAT, however, broad orientation selectivity emerges in tPV interneurons. Transplantation does not alter orientation selectivity in host interneurons, suggesting that the maturation of tPV interneurons occurs independently from their endogenous counterparts. Together, these results challenge the notion that the onset of vision solely determines when PV interneurons become broadly tuned. Our results reveal that an innate cortical mechanism contributes to the emergence of broad orientation selectivity in PV interneurons. SIGNIFICANCE STATEMENT Early visual experience and innate developmental programs interact to shape cortical circuits. Visual-deprivation experiments have suggested that the onset of visual experience determines when interneurons mature in the visual cortex. Here we used neuronal transplantation and cellular imaging of visual responses to investigate the maturation of parvalbumin-positive (PV) interneurons. Our results suggest that the emergence of broad orientation selectivity in PV interneurons is innately timed. PMID:28123018
Ringach, Dario L.; Hawken, Michael J.; Shapley, Robert M.
2011-01-01
One of the functions of the cerebral cortex is to increase the selectivity for stimulus features. Finding more about the mechanisms of increased cortical selectivity is important for understanding how the cortex works. Up to now, studies in multiple cortical areas have reported that suppressive mechanisms are involved in feature selectivity. However, the magnitude of the contribution of suppression to tuning selectivity is not yet determined. We use orientation selectivity in macaque primary visual cortex, V1, as an archetypal example of cortical feature selectivity and develop a method to estimate the magnitude of the contribution of suppression to orientation selectivity. The results show that untuned suppression, one form of cortical suppression, decreases the orthogonal-to-preferred response ratio (O/P ratio) of V1 cells from an average of 0.38 to 0.26. Untuned suppression has an especially large effect on orientation selectivity for highly selective cells (O/P < 0.2). Therefore, untuned suppression is crucial for the generation of highly orientation-selective cells in V1 cortex. PMID:22049440
Phase-shifting point diffraction interferometer mask designs
Goldberg, Kenneth Alan
2001-01-01
In a phase-shifting point diffraction interferometer, different image-plane mask designs can improve the operation of the interferometer. By keeping the test beam window of the mask small compared to the separation distance between the beams, the problem of energy from the reference beam leaking through the test beam window is reduced. By rotating the grating and mask 45.degree., only a single one-dimensional translation stage is required for phase-shifting. By keeping two reference pinholes in the same orientation about the test beam window, only a single grating orientation, and thus a single one-dimensional translation stage, is required. The use of a two-dimensional grating allows for a multiplicity of pinholes to be used about the pattern of diffracted orders of the grating at the mask. Orientation marks on the mask can be used to orient the device and indicate the position of the reference pinholes.
NASA Technical Reports Server (NTRS)
Frew, A. M.; Eisenhut, D. F.; Farrenkopf, R. L.; Gates, R. F.; Iwens, R. P.; Kirby, D. K.; Mann, R. J.; Spencer, D. J.; Tsou, H. S.; Zaremba, J. G.
1972-01-01
The precision pointing control system (PPCS) is an integrated system for precision attitude determination and orientation of gimbaled experiment platforms. The PPCS concept configures the system to perform orientation of up to six independent gimbaled experiment platforms to design goal accuracy of 0.001 degrees, and to operate in conjunction with a three-axis stabilized earth-oriented spacecraft in orbits ranging from low altitude (200-2500 n.m., sun synchronous) to 24 hour geosynchronous, with a design goal life of 3 to 5 years. The system comprises two complementary functions: (1) attitude determination where the attitude of a defined set of body-fixed reference axes is determined relative to a known set of reference axes fixed in inertial space; and (2) pointing control where gimbal orientation is controlled, open-loop (without use of payload error/feedback) with respect to a defined set of body-fixed reference axes to produce pointing to a desired target.
NASA Astrophysics Data System (ADS)
Islam, Tariqul; Islam, Md. Saiful; Shajid-Ul-Mahmud, Md.; Hossam-E-Haider, Md
2017-12-01
An Attitude Heading Reference System (AHRS) provides 3D orientation of an aircraft (roll, pitch, and yaw) with instantaneous position and also heading information. For implementation of a low cost AHRS system Micro-electrical-Mechanical system (MEMS) based sensors are used such as accelerometer, gyroscope, and magnetometer. Accelerometers suffer from errors caused by external accelerations that sums to gravity and make accelerometers based rotation inaccurate. Gyroscopes can remove such errors but create drifting problems. So for getting the precise data additionally two very common and well known filters Complementary and Kalman are introduced to the system. In this paper a comparison of system performance using these two filters is shown separately so that one would be able to select filter with better performance for his/her system.
The relation between gender role orientation and fear and anxiety in nonclinic-referred children.
Muris, Peter; Meesters, Cor; Knoops, Miranda
2005-06-01
This study examined the relation between gender role orientation and fear and anxiety in a sample of nonclinic-referred children (N = 209) ages 10 to 13 years. Children and their parents completed questionnaires assessing children's gender role orientation, toy and activity preferences, and fear and anxiety. Results generally indicated that femininity and a preference for girls' toys and activities were positively associated with fear and anxiety, whereas masculinity and a preference for boys' toys and activities were negatively related to these emotions. Furthermore, gender role orientation accounted for more of the variance in fear and anxiety scores than the child's sex.
The influence of visual and vestibular orientation cues in a clock reading task.
Davidenko, Nicolas; Cheong, Yeram; Waterman, Amanda; Smith, Jacob; Anderson, Barrett; Harmon, Sarah
2018-05-23
We investigated how performance in the real-life perceptual task of analog clock reading is influenced by the clock's orientation with respect to egocentric, gravitational, and visual-environmental reference frames. In Experiment 1, we designed a simple clock-reading task and found that observers' reaction time to correctly tell the time depends systematically on the clock's orientation. In Experiment 2, we dissociated egocentric from environmental reference frames by having participants sit upright or lie sideways while performing the task. We found that both reference frames substantially contribute to response times in this task. In Experiment 3, we placed upright or rotated participants in an upright or rotated immersive virtual environment, which allowed us to further dissociate vestibular from visual cues to the environmental reference frame. We found evidence of environmental reference frame effects only when visual and vestibular cues were aligned. We discuss the implications for the design of remote and head-mounted displays. Copyright © 2018 Elsevier Inc. All rights reserved.
Distortions in memory for visual displays
NASA Technical Reports Server (NTRS)
Tversky, Barbara
1989-01-01
Systematic errors in perception and memory present a challenge to theories of perception and memory and to applied psychologists interested in overcoming them as well. A number of systematic errors in memory for maps and graphs are reviewed, and they are accounted for by an analysis of the perceptual processing presumed to occur in comprehension of maps and graphs. Visual stimuli, like verbal stimuli, are organized in comprehension and memory. For visual stimuli, the organization is a consequence of perceptual processing, which is bottom-up or data-driven in its earlier stages, but top-down and affected by conceptual knowledge later on. Segregation of figure from ground is an early process, and figure recognition later; for both, symmetry is a rapidly detected and ecologically valid cue. Once isolated, figures are organized relative to one another and relative to a frame of reference. Both perceptual (e.g., salience) and conceptual factors (e.g., significance) seem likely to affect selection of a reference frame. Consistent with the analysis, subjects perceived and remembered curves in graphs and rivers in maps as more symmetric than they actually were. Symmetry, useful for detecting and recognizing figures, distorts map and graph figures alike. Top-down processes also seem to operate in that calling attention to the symmetry vs. asymmetry of a slightly asymmetric curve yielded memory errors in the direction of the description. Conceptual frame of reference effects were demonstrated in memory for lines embedded in graphs. In earlier work, the orientation of map figures was distorted in memory toward horizontal or vertical. In recent work, graph lines, but not map lines, were remembered as closer to an imaginary 45 deg line than they had been. Reference frames are determined by both perceptual and conceptual factors, leading to selection of the canonical axes as a reference frame in maps, but selection of the imaginary 45 deg as a reference frame in graphs.
Current Limitations on VLBI Accuracy
NASA Technical Reports Server (NTRS)
Ma, Chopo; Gipson, John; MacMillan, Daniel
1998-01-01
The contribution of VLBI to geophysics and geodesy arises from its ability to measure distances between stations in a network and to determine the orientation of stations in the network as well as the orientation of the network with respect to the external reference frame of extragalactic radio objects. Integrating nearly two decades of observations provides useful information about station positions and velocities and the orientation of the Earth, but the complications of the real world and the limitations of observing, modeling and analysis prevent recovery of all effects. Of the factors that limit the accuracy of seemingly straightforward geodetic parameters, the neutral propagation medium has been subject to the greatest scrutiny, but the treatment of the mapping function, the wet component and spatial/temporal inhomogeneities is still improving. These affect both the terrestrial scale and consistency over time. The modeling of non-secular site motions (tides and loading) has increased in sophistication, but there are some differences between the models and the observations. VLBI antennas are massive objects, so their behavior is quite unlike GPS monuments, but antenna deformations add some (generally) unmodeled signal. Radio sources used in geodetic VLBI observations are selected for strength and (relative) absence of structure, but apparent changes in position can leak into geodetic parameters. A linear rate of change of baseline or site parameters is the simplest model and its error improves with time span. However, in most cases the VLBI data distribution is insufficient to look for real non-linear behavior that might affect the average rate. A few sites have multiple VLBI antennas, and some show small differences in rate. VLBI intrinsically measures relative positions and velocities, but individual site positions and velocities are generally more useful. The creation of the VLBI terrestrial reference frame, which transforms relative information into individual results, is an empirical process that has intrinsic errors. While UT1 is uniquely measured by VLBI, the geographical distribution and availability of VLBI stations, especially in the southern hemisphere, and the consistency of the VLBI terrestrial reference frame may limit the accuracy of Earth orientation measurements. The effects of particular error sources on geodetic and geophysical parameters derived from VLBI data will be illustrated.
Du, Feng; Abrams, Richard A
2012-09-01
To avoid sensory overload, people are able to selectively attend to a particular color or direction of motion while ignoring irrelevant stimuli that differ from the desired one. We show here for the first time that it is also possible to selectively attend to a specific line orientation-but with an important caveat: orientations that are perpendicular to the target orientation cannot be suppressed. This effect reflects properties of the neural mechanisms selective for orientation and reveals the extent to which contingent capture is constrained not only by one's top-down goals but also by feature preferences of visual neurons. Copyright © 2012 Elsevier B.V. All rights reserved.
A multichip aVLSI system emulating orientation selectivity of primary visual cortical cells.
Shimonomura, Kazuhiro; Yagi, Tetsuya
2005-07-01
In this paper, we designed and fabricated a multichip neuromorphic analog very large scale integrated (aVLSI) system, which emulates the orientation selective response of the simple cell in the primary visual cortex. The system consists of a silicon retina and an orientation chip. An image, which is filtered by a concentric center-surround (CS) antagonistic receptive field of the silicon retina, is transferred to the orientation chip. The image transfer from the silicon retina to the orientation chip is carried out with analog signals. The orientation chip selectively aggregates multiple pixels of the silicon retina, mimicking the feedforward model proposed by Hubel and Wiesel. The chip provides the orientation-selective (OS) outputs which are tuned to 0 degrees, 60 degrees, and 120 degrees. The feed-forward aggregation reduces the fixed pattern noise that is due to the mismatch of the transistors in the orientation chip. The spatial properties of the orientation selective response were examined in terms of the adjustable parameters of the chip, i.e., the number of aggregated pixels and size of the receptive field of the silicon retina. The multichip aVLSI architecture used in the present study can be applied to implement higher order cells such as the complex cell of the primary visual cortex.
ERIC Educational Resources Information Center
Tomeh, Aida K.; Vasko, Catherine
This paper examines the role of parents and friends (reference groups) in forming college students' sex-role orientations. Emphasis is placed on the mother's domestic, parental, and achieved (professional/occupational) role and on the mother's modeling transmission effect on her daughter's and son's sex-role attitudes. The hypothesis is that…
NASA Technical Reports Server (NTRS)
1973-01-01
The retrieval command subsystem reference manual for the NASA Aerospace Safety Information System (NASIS) is presented. The command subsystem may be operated conversationally or in the batch mode. Retrieval commands are categorized into search-oriented and output-oriented commands. The characteristics of ancillary commands and their application are reported.
Sensitivity Profile for Orientation Selectivity in the Visual Cortex of Goggle-Reared Mice
Yoshida, Takamasa; Ozawa, Katsuya; Tanaka, Shigeru
2012-01-01
It has been widely accepted that ocular dominance in the responses of visual cortical neurons can change depending on visual experience in a postnatal period. However, experience-dependent plasticity for orientation selectivity, which is another important response property of visual cortical neurons, is not yet fully understood. To address this issue, using intrinsic signal imaging and two-photon calcium imaging we attempted to observe the alteration of orientation selectivity in the visual cortex of juvenile and adult mice reared with head-mounted goggles, through which animals can experience only the vertical orientation. After one week of goggle rearing, the density of neurons optimally responding to the exposed orientation increased, while that responding to unexposed orientations decreased. These changes can be interpreted as a reallocation of preferred orientations among visually responsive neurons. Our obtained sensitivity profile for orientation selectivity showed a marked peak at 5 weeks and sustained elevation at 12 weeks and later. These features indicate the existence of a critical period between 4 and 7 weeks and residual orientation plasticity in adult mice. The presence of a dip in the sensitivity profile at 10 weeks suggests that different mechanisms are involved in orientation plasticity in childhood and adulthood. PMID:22792390
Development and matching of binocular orientation preference in mouse V1.
Bhaumik, Basabi; Shah, Nishal P
2014-01-01
Eye-specific thalamic inputs converge in the primary visual cortex (V1) and form the basis of binocular vision. For normal binocular perceptions, such as depth and stereopsis, binocularly matched orientation preference between the two eyes is required. A critical period of binocular matching of orientation preference in mice during normal development is reported in literature. Using a reaction diffusion model we present the development of RF and orientation selectivity in mouse V1 and investigate the binocular orientation preference matching during the critical period. At the onset of the critical period the preferred orientations of the modeled cells are mostly mismatched in the two eyes and the mismatch decreases and reaches levels reported in juvenile mouse by the end of the critical period. At the end of critical period 39% of cells in binocular zone in our model cortex is orientation selective. In literature around 40% cortical cells are reported as orientation selective in mouse V1. The starting and the closing time for critical period determine the orientation preference alignment between the two eyes and orientation tuning in cortical cells. The absence of near neighbor interaction among cortical cells during the development of thalamo-cortical wiring causes a salt and pepper organization in the orientation preference map in mice. It also results in much lower % of orientation selective cells in mice as compared to ferrets and cats having organized orientation maps with pinwheels.
Kuhlmann, Levin; Vidyasagar, Trichur R.
2011-01-01
Controversy remains about how orientation selectivity emerges in simple cells of the mammalian primary visual cortex. In this paper, we present a computational model of how the orientation-biased responses of cells in lateral geniculate nucleus (LGN) can contribute to the orientation selectivity in simple cells in cats. We propose that simple cells are excited by lateral geniculate fields with an orientation-bias and disynaptically inhibited by unoriented lateral geniculate fields (or biased fields pooled across orientations), both at approximately the same retinotopic co-ordinates. This interaction, combined with recurrent cortical excitation and inhibition, helps to create the sharp orientation tuning seen in simple cell responses. Along with describing orientation selectivity, the model also accounts for the spatial frequency and length–response functions in simple cells, in normal conditions as well as under the influence of the GABAA antagonist, bicuculline. In addition, the model captures the response properties of LGN and simple cells to simultaneous visual stimulation and electrical stimulation of the LGN. We show that the sharp selectivity for stimulus orientation seen in primary visual cortical cells can be achieved without the excitatory convergence of the LGN input cells with receptive fields along a line in visual space, which has been a core assumption in classical models of visual cortex. We have also simulated how the full range of orientations seen in the cortex can emerge from the activity among broadly tuned channels tuned to a limited number of optimum orientations, just as in the classical case of coding for color in trichromatic primates. PMID:22013414
Levichkina, Ekaterina; Saalmann, Yuri B; Vidyasagar, Trichur R
2017-03-01
Primate posterior parietal cortex (PPC) is known to be involved in controlling spatial attention. Neurons in one part of the PPC, the lateral intraparietal area (LIP), show enhanced responses to objects at attended locations. Although many are selective for object features, such as the orientation of a visual stimulus, it is not clear how LIP circuits integrate feature-selective information when providing attentional feedback about behaviorally relevant locations to the visual cortex. We studied the relationship between object feature and spatial attention properties of LIP cells in two macaques by measuring the cells' orientation selectivity and the degree of attentional enhancement while performing a delayed match-to-sample task. Monkeys had to match both the location and orientation of two visual gratings presented separately in time. We found a wide range in orientation selectivity and degree of attentional enhancement among LIP neurons. However, cells with significant attentional enhancement had much less orientation selectivity in their response than cells which showed no significant modulation by attention. Additionally, orientation-selective cells showed working memory activity for their preferred orientation, whereas cells showing attentional enhancement also synchronized with local neuronal activity. These results are consistent with models of selective attention incorporating two stages, where an initial feature-selective process guides a second stage of focal spatial attention. We suggest that LIP contributes to both stages, where the first stage involves orientation-selective LIP cells that support working memory of the relevant feature, and the second stage involves attention-enhanced LIP cells that synchronize to provide feedback on spatial priorities. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.
Parental selection of children's sexual orientation.
Greenberg, A S; Bailey, J M
2001-08-01
As we learn more about the causes of sexual orientation, the likelihood increases that parents will one day be able to select the orientation of their children. This possibility (at least that of selecting for heterosexuality) has generated a great deal of concern among supporters of homosexual rights, with such selection being widely condemned as harmful and morally repugnant. Notwithstanding this widespread condemnation, and even assuming, as we do, that homosexuality is entirely acceptable morally, allowing parents, by means morally unproblematic in themselves, to select for heterosexuality would be morally acceptable. This is because allowing parents to select their children's sexual orientation would further parent's freedom to raise the sort of children they wish to raise and because selection for heterosexuality may benefit parents and children and is unlikely to cause significant harm.
Long adaptation reveals mostly attractive shifts of orientation tuning in cat primary visual cortex.
Ghisovan, N; Nemri, A; Shumikhina, S; Molotchnikoff, S
2009-12-15
In the adult brain, sensory cortical neurons undergo transient changes of their response properties following prolonged exposure to an appropriate stimulus (adaptation). In cat V1, orientation-selective cells shift their preferred orientation after being adapted to a non-preferred orientation. There are conflicting reports as to the direction of those shifts, towards (attractive) or away (repulsive) from the adapter. Moreover, the mechanisms underlying attractive shifts remain unexplained. In the present investigation we show that attractive shifts are the most frequent outcome of a 12 min adaptation. Overall, cells displaying selectivity for oblique orientations exhibit significantly larger shifts than cells tuned to cardinal orientations. In addition, cells selective to cardinal orientations had larger shift amplitudes when the absolute difference between the original preferred orientation and the adapting orientation increased. Conversely, cells tuned to oblique orientations exhibited larger shift amplitudes when this absolute orientation difference was narrower. Hence, neurons tuned to oblique contours appear to show more plasticity in response to small perturbations. Two different mechanisms appear to produce attractive and repulsive orientation shifts. Attractive shifts result from concurrent response depression on the non-adapted flank and selective response facilitation on the adapted flank of the orientation tuning curve. In contrast, repulsive shifts are caused solely by response depression on the adapted flank. We suggest that an early mechanism leads to repulsive shifts while attractive shifts engage a subsequent late facilitation. A potential role for attractive shifts may be improved stimulus discrimination around the adapting orientation.
Two symmetry-breaking mechanisms for the development of orientation selectivity in a neural system
NASA Astrophysics Data System (ADS)
Cho, Myoung Won; Chun, Min Young
2015-11-01
Orientation selectivity is a remarkable feature of the neurons located in the primary visual cortex. Provided that the visual neurons acquire orientation selectivity through activity-dependent Hebbian learning, the development process could be understood as a kind of symmetry-breaking phenomenon in the view of physics. This paper examines the key mechanisms of the orientation selectivity development process. Be found that at least two different mechanisms, which lead to the development of orientation selectivity by breaking the radial symmetry in receptive fields. The first is a simultaneous symmetry-breaking mechanism occurring based on the competition between neighboring neurons, and the second is a spontaneous one occurring based on the nonlinearity in interactions. Only the second mechanism leads to the formation of a columnar pattern whose characteristics is in accord with those observed in an animal experiment.
Seismic Station Installation Orientation Errors at ANSS and IRIS/USGS Stations
Ringler, Adam T.; Hutt, Charles R.; Persfield, K.; Gee, Lind S.
2013-01-01
Many seismological studies depend on the published orientations of sensitive axes of seismic instruments relative to north (e.g., Li et al., 2011). For example, studies of the anisotropic structure of the Earth’s mantle through SKS‐splitting measurements (Long et al., 2009), constraints on core–mantle electromagnetic coupling from torsional normal‐mode measurements (Dumberry and Mound, 2008), and models of three‐dimensional (3D) velocity variations from surface waves (Ekström et al., 1997) rely on accurate sensor orientation. Unfortunately, numerous results indicate that this critical parameter is often subject to significant error (Laske, 1995; Laske and Masters, 1996; Yoshizawa et al., 1999; Schulte‐Pelkum et al., 2001; Larson and Ekström, 2002). For the Advanced National Seismic System (ANSS; ANSS Technical Integration Committee, 2002), the Global Seismographic Network (GSN; Butler et al., 2004), and many other networks, sensor orientation is typically determined by a field engineer during installation. Successful emplacement of a seismic instrument requires identifying true north, transferring a reference line, and measuring the orientation of the instrument relative to the reference line. Such an exercise is simple in theory, but there are many complications in practice. There are four commonly used methods for determining true north at the ANSS and GSN stations operated by the USGS Albuquerque Seismological Laboratory (ASL), including gyroscopic, astronomical, Global Positioning System (GPS), and magnetic field techniques. A particular method is selected based on site conditions (above ground, below ground, availability of astronomical observations, and so on) and in the case of gyroscopic methods, export restrictions. Once a north line has been determined, it must be translated to the sensor location. For installations in mines or deep vaults, this step can include tracking angles through the one or more turns in the access tunnel leading to the vault (e.g., GSN station WCI in Wyandotte Cave, Indiana). Finally, the third source of error comes from the ability of field engineers to orient the sensor relative to the reference line. In order to quantify bounds on the errors in each step in the orientation process, we conducted a series of tests at the ASL using twelve GSN and ANSS field engineers. The results from this exercise allow us to estimate upper bounds on the precision of our ability to orient instruments, as well as identify the sources of error in the procedures. We are also able to identify systematic bias of various true‐north‐finding methods relative to one another. Although we are unable to estimate the absolute accuracy of our orientation measurements due to our inability to identify true north without some error, the agreement between independent methods for finding true north provides confidence in the different approaches, assuming no systematic bias. Finally, our study neglects orientation errors that are beyond the control of the field engineer during a station visit. These additional errors can arise from deviations in the sensitive axes of the instruments relative to the case markings, processing errors (Holcomb, 2002) when comparing horizontal orientations relative to other sensors (e.g., borehole installations), and deviations of the sensitive axes of instruments from true orthogonality (e.g., instruments with separate modules such as the Streckeisen STS‐1).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Xue, Guobiao; Zhao, Xikang; Qu, Ge
The selection of side chains is important in design of conjugated polymers. It not only affects their intrinsic physical properties, but also has an impact on thin film morphologies. Recent reports suggested that a face-on/edge-on bimodal orientation observed in polymer thin films may be responsible for a three-dimensional (3D) charge transport and leads to dramatically improved mobility in donor–acceptor based conjugated polymers. To achieve a bimodal orientation in thin films has been seldom explored from the aspect of molecular design. Here, we demonstrate a design strategy involving the use of asymmetric side chains that enables an isoindigo-based polymer to adoptmore » a distinct bimodal orientation, confirmed by the grazing incidence X-ray diffraction. As a result, the polymer presents an average high mobility of 3.8 ± 0.7 cm2 V–1 s–1 with a maximum value of 5.1 cm2 V–1 s–1, in comparison with 0.47 and 0.51 cm2 V–1 s–1 obtained from the two reference polymers. This study exemplifies a new strategy to develop the next generation polymers through understanding the property-structure relationship.« less
Orientation-Selective Retinal Circuits in Vertebrates.
Antinucci, Paride; Hindges, Robert
2018-01-01
Visual information is already processed in the retina before it is transmitted to higher visual centers in the brain. This includes the extraction of salient features from visual scenes, such as motion directionality or contrast, through neurons belonging to distinct neural circuits. Some retinal neurons are tuned to the orientation of elongated visual stimuli. Such 'orientation-selective' neurons are present in the retinae of most, if not all, vertebrate species analyzed to date, with species-specific differences in frequency and degree of tuning. In some cases, orientation-selective neurons have very stereotyped functional and morphological properties suggesting that they represent distinct cell types. In this review, we describe the retinal cell types underlying orientation selectivity found in various vertebrate species, and highlight their commonalities and differences. In addition, we discuss recent studies that revealed the cellular, synaptic and circuit mechanisms at the basis of retinal orientation selectivity. Finally, we outline the significance of these findings in shaping our current understanding of how this fundamental neural computation is implemented in the visual systems of vertebrates.
Cieslowski, B J; Wajngurt, D; Cimino, J J; Bakken, S
2001-01-01
Recent investigations have tested the applicability of various terminology models for the representing nursing concepts including those related to nursing diagnoses, nursing interventions, and standardized nursing assessments as a prerequisite for building a reference terminology that supports the nursing domain. We used the semantic structure of Clinical LOINC (Logical Observations, Identifiers, Names, and Codes) as a reference terminology model to support the integration of standardized assessment terms from two nursing terminologies into the Medical Entities Dictionary (MED), the concept-oriented, metadata dictionary at New York Presbyterian Hospital. Although the LOINC semantic structure was used previously to represent laboratory terms in the MED, selected hierarchies and semantic slots required revisions in order to incorporate the nursing assessment concepts. This project was an initial step in integrating nursing assessment concepts into the MED in a manner consistent with evolving standards for reference terminology models. Moreover, the revisions provide the foundation for adding other types of standardized assessments to the MED.
Cieslowski, B. J.; Wajngurt, D.; Cimino, J. J.; Bakken, S.
2001-01-01
Recent investigations have tested the applicability of various terminology models for the representing nursing concepts including those related to nursing diagnoses, nursing interventions, and standardized nursing assessments as a prerequisite for building a reference terminology that supports the nursing domain. We used the semantic structure of Clinical LOINC (Logical Observations, Identifiers, Names, and Codes) as a reference terminology model to support the integration of standardized assessment terms from two nursing terminologies into the Medical Entities Dictionary (MED), the concept-oriented, metadata dictionary at New York Presbyterian Hospital. Although the LOINC semantic structure was used previously to represent laboratory terms in the MED, selected hierarchies and semantic slots required revisions in order to incorporate the nursing assessment concepts. This project was an initial step in integrating nursing assessment concepts into the MED in a manner consistent with evolving standards for reference terminology models. Moreover, the revisions provide the foundation for adding other types of standardized assessments to the MED. PMID:11825165
Hausselle, Jerome; Moreau, Pierre Etienne; Wessely, Loic; de Thomasson, Emmanuel; Assi, Ayman; Parratte, Sebastien; Essig, Jerome; Skalli, Wafa
2012-08-01
Acetabular component malalignment in total hip arthroplasty can lead to potential complications such as dislocation, component impingement and excessive wear. Computer-assisted orthopaedic surgery systems generally use the anterior pelvic plane (APP). Our aim was to investigate the reliability of anatomical landmarks accessible during surgery and to define new potential planes of reference. Three types of palpations were performed: virtual, on dry bones and on two cadaveric specimens. Four landmarks were selected, the reproducibility of their positioning ranging from 0.9 to 2.3 mm. We then defined five planes and tested them during palpations on two cadaveric specimens. Two planes produced a mean orientation error of 5.0° [standard deviation (SD 3.3°)] and 5.6° (SD 2.7°). Even if further studies are needed to test the reliability of such planes on a larger scale in vivo during surgery, these results demonstrated the feasibility of defining a new plane of reference as an alternative to the APP.
Orientation and metacognition in virtual space.
Tenbrink, Thora; Salwiczek, Lucie H
2016-05-01
Cognitive scientists increasingly use virtual reality scenarios to address spatial perception, orientation, and navigation. If based on desktops rather than mobile immersive environments, this involves a discrepancy between the physically experienced static position and the visually perceived dynamic scene, leading to cognitive challenges that users of virtual worlds may or may not be aware of. The frequently reported loss of orientation and worse performance in point-to-origin tasks relate to the difficulty of establishing a consistent reference system on an allocentric or egocentric basis. We address the verbalizability of spatial concepts relevant in this regard, along with the conscious strategies reported by participants. Behavioral and verbal data were collected using a perceptually sparse virtual tunnel scenario that has frequently been used to differentiate between humans' preferred reference systems. Surprisingly, the linguistic data we collected relate to reference system verbalizations known from the earlier literature only to a limited extent, but instead reveal complex cognitive mechanisms and strategies. Orientation in desktop virtual reality appears to pose considerable challenges, which participants react to by conceptualizing the task in individual ways that do not systematically relate to the generic concepts of egocentric and allocentric reference frames. (c) 2016 APA, all rights reserved).
A linear model fails to predict orientation selectivity of cells in the cat visual cortex.
Volgushev, M; Vidyasagar, T R; Pei, X
1996-01-01
1. Postsynaptic potentials (PSPs) evoked by visual stimulation in simple cells in the cat visual cortex were recorded using in vivo whole-cell technique. Responses to small spots of light presented at different positions over the receptive field and responses to elongated bars of different orientations centred on the receptive field were recorded. 2. To test whether a linear model can account for orientation selectivity of cortical neurones, responses to elongated bars were compared with responses predicted by a linear model from the receptive field map obtained from flashing spots. 3. The linear model faithfully predicted the preferred orientation, but not the degree of orientation selectivity or the sharpness of orientation tuning. The ratio of optimal to non-optimal responses was always underestimated by the model. 4. Thus non-linear mechanisms, which can include suppression of non-optimal responses and/or amplification of optimal responses, are involved in the generation of orientation selectivity in the primary visual cortex. PMID:8930828
Orientation selectivity and the functional clustering of synaptic inputs in primary visual cortex
Wilson, Daniel E.; Whitney, David E.; Scholl, Benjamin; Fitzpatrick, David
2016-01-01
The majority of neurons in primary visual cortex are tuned for stimulus orientation, but the factors that account for the range of orientation selectivities exhibited by cortical neurons remain unclear. To address this issue, we used in vivo 2-photon calcium imaging to characterize the orientation tuning and spatial arrangement of synaptic inputs to the dendritic spines of individual pyramidal neurons in layer 2/3 of ferret visual cortex. The summed synaptic input to individual neurons reliably predicted the neuron’s orientation preference, but did not account for differences in orientation selectivity among neurons. These differences reflected a robust input-output nonlinearity that could not be explained by spike threshold alone, and was strongly correlated with the spatial clustering of co-tuned synaptic inputs within the dendritic field. Dendritic branches with more co-tuned synaptic clusters exhibited greater rates of local dendritic calcium events supporting a prominent role for functional clustering of synaptic inputs in dendritic nonlinearities that shape orientation selectivity. PMID:27294510
Conservative orientation as a determinant of hopelessness.
Cheung, C K; Kwok, S T
1996-06-01
Conservative orientation is identified with reference to authoritarianism, work ethic belief, just world belief, and endorsement of individualistic causes of social problems. This over-arching orientation is hypothesized to affect hopelessness and to be affected by self-esteem with reference to ego development theory and learned helplessness theory. Causal modeling of data obtained from 1st-year college students (N = 556) in Hong Kong supports the hypotheses, showing that a student's hopelessness relates to his or her conservative orientation, even when self-esteem is controlled. This relationship can be interpreted by ego development and learned helplessness theories and cannot be explained as a spurious effect. Through the theories, hopelessness is interpreted as a result of maladaptive development and fatalistic, alienated, and helpless outlooks. This maladaptive development and the outlooks in turn result from students' conservative and individualistic orientation.
Non-GPS full position and angular orientation onboard sensors for moving and stationary platforms
NASA Astrophysics Data System (ADS)
Dhadwal, Harbans S.; Rastegar, Jahangir; Feng, Dake; Kwok, Philip; Pereira, Carlos M.
2016-05-01
Angular orientation of both mobile and stationary objects continues to be an ongoing topic of interest for guidance and control as well as for non-GPS based solutions for geolocations of assets in any environment. Currently available sensors, which include inertia devices such as accelerometers and gyros; magnetometers; surface mounted antennas; radars; GPS; and optical line of sight devices, do not provide an acceptable solution for many applications, particularly for gun-fired munitions and for all-weather and all environment scenarios. A robust onboard full angular orientation sensor solution, based on a scanning polarized reference source and a polarized geometrical cavity orientation sensor, is presented. The full position of the object, in the reference source coordinate system, is determined by combining range data obtained using established time-of-flight techniques, with the angular orientation information.
Expected Improvements in VLBI Measurements of the Earth's Orientation
NASA Technical Reports Server (NTRS)
Ma, Chopo
2003-01-01
Measurements of the Earth s orientation since the 1970s using space geodetic techniques have provided a continually expanding and improving data set for studies of the Earth s structure and the distribution of mass and angular momentum. The accuracy of current one-day measurements is better than 100 microarcsec for the motion of the pole with respect to the celestial and terrestrial reference frames and better than 3 microsec for the rotation around the pole. VLBI uniquely provides the three Earth orientation parameters (nutation and UTI) that relate the Earth to the extragalactic celestial reference frame. The accuracy and resolution of the VLBI Earth orientation time series can be expected to improve substantially in the near future because of refinements in the realization of the celestial reference frame, improved modeling of the troposphere and non-linear station motions, larger observing networks, optimized scheduling, deployment of disk-based Mark V recorders, full use of Mark IV capabilities, and e-VLBI. More radical future technical developments will be discussed.
Dissociation of neural mechanisms underlying orientation processing in humans
Ling, Sam; Pearson, Joel; Blake, Randolph
2009-01-01
Summary Orientation selectivity is a fundamental, emergent property of neurons in early visual cortex, and discovery of that property [1, 2] dramatically shaped how we conceptualize visual processing [3–6]. However, much remains unknown about the neural substrates of these basic building blocks of perception, and what is known primarily stems from animal physiology studies. To probe the neural concomitants of orientation processing in humans, we employed repetitive transcranial magnetic stimulation (rTMS) to attenuate neural responses evoked by stimuli presented within a local region of the visual field. Previous physiological studies have shown that rTMS can significantly suppress the neuronal spiking activity, hemodynamic responses, and local field potentials within a focused cortical region [7, 8]. By suppressing neural activity with rTMS, we were able to dissociate components of the neural circuitry underlying two distinct aspects of orientation processing: selectivity and contextual effects. Orientation selectivity gauged by masking was unchanged by rTMS, whereas an otherwise robust orientation repulsion illusion was weakened following rTMS. This dissociation implies that orientation processing relies on distinct mechanisms, only one of which was impacted by rTMS. These results are consistent with models positing that orientation selectivity is largely governed by the patterns of convergence of thalamic afferents onto cortical neurons, with intracortical activity then shaping population responses contained within those orientation-selective cortical neurons. PMID:19682905
Development and matching of binocular orientation preference in mouse V1
Bhaumik, Basabi; Shah, Nishal P.
2014-01-01
Eye-specific thalamic inputs converge in the primary visual cortex (V1) and form the basis of binocular vision. For normal binocular perceptions, such as depth and stereopsis, binocularly matched orientation preference between the two eyes is required. A critical period of binocular matching of orientation preference in mice during normal development is reported in literature. Using a reaction diffusion model we present the development of RF and orientation selectivity in mouse V1 and investigate the binocular orientation preference matching during the critical period. At the onset of the critical period the preferred orientations of the modeled cells are mostly mismatched in the two eyes and the mismatch decreases and reaches levels reported in juvenile mouse by the end of the critical period. At the end of critical period 39% of cells in binocular zone in our model cortex is orientation selective. In literature around 40% cortical cells are reported as orientation selective in mouse V1. The starting and the closing time for critical period determine the orientation preference alignment between the two eyes and orientation tuning in cortical cells. The absence of near neighbor interaction among cortical cells during the development of thalamo-cortical wiring causes a salt and pepper organization in the orientation preference map in mice. It also results in much lower % of orientation selective cells in mice as compared to ferrets and cats having organized orientation maps with pinwheels. PMID:25104927
Neural field model to reconcile structure with function in primary visual cortex.
Rankin, James; Chavane, Frédéric
2017-10-01
Voltage-sensitive dye imaging experiments in primary visual cortex (V1) have shown that local, oriented visual stimuli elicit stable orientation-selective activation within the stimulus retinotopic footprint. The cortical activation dynamically extends far beyond the retinotopic footprint, but the peripheral spread stays non-selective-a surprising finding given a number of anatomo-functional studies showing the orientation specificity of long-range connections. Here we use a computational model to investigate this apparent discrepancy by studying the expected population response using known published anatomical constraints. The dynamics of input-driven localized states were simulated in a planar neural field model with multiple sub-populations encoding orientation. The realistic connectivity profile has parameters controlling the clustering of long-range connections and their orientation bias. We found substantial overlap between the anatomically relevant parameter range and a steep decay in orientation selective activation that is consistent with the imaging experiments. In this way our study reconciles the reported orientation bias of long-range connections with the functional expression of orientation selective neural activity. Our results demonstrate this sharp decay is contingent on three factors, that long-range connections are sufficiently diffuse, that the orientation bias of these connections is in an intermediate range (consistent with anatomy) and that excitation is sufficiently balanced by inhibition. Conversely, our modelling results predict that, for reduced inhibition strength, spurious orientation selective activation could be generated through long-range lateral connections. Furthermore, if the orientation bias of lateral connections is very strong, or if inhibition is particularly weak, the network operates close to an instability leading to unbounded cortical activation.
Orientation selectivity based structure for texture classification
NASA Astrophysics Data System (ADS)
Wu, Jinjian; Lin, Weisi; Shi, Guangming; Zhang, Yazhong; Lu, Liu
2014-10-01
Local structure, e.g., local binary pattern (LBP), is widely used in texture classification. However, LBP is too sensitive to disturbance. In this paper, we introduce a novel structure for texture classification. Researches on cognitive neuroscience indicate that the primary visual cortex presents remarkable orientation selectivity for visual information extraction. Inspired by this, we investigate the orientation similarities among neighbor pixels, and propose an orientation selectivity based pattern for local structure description. Experimental results on texture classification demonstrate that the proposed structure descriptor is quite robust to disturbance.
Scientific Understanding of Sexual Orientation: Implications for Science Education.
ERIC Educational Resources Information Center
Good, Ron; Hafner, Mark; Peebles, Patsye
2000-01-01
Discusses sexual orientation using the analogy of handedness. Points out the presence of diverse sexual behavior and homosexuality among living species and focuses on human behavior. Encourages discussions among biology teachers on the origins of sexual orientation. (Contains 27 references.) (YDS)
ERIC Educational Resources Information Center
Nargund-Joshi, Vanashri
2012-01-01
This study explores the concepts and behaviors, otherwise referred to as "orientations", of six Indian science teachers and the alignment of these orientations to the 2005 India National Curriculum Framework (NCF-2005). Differences in teachers' orientations across grade bands (elementary, middle, and secondary) and school types (public…
Mediano Stoltze, Fernanda; Barker, Joshua O; Kanter, Rebecca; Corvalán, Camila; Reyes, Marcela; Taillie, Lindsey Smith; Dillman Carpentier, Francesca R
2018-02-01
Front-of-package (FOP) marketing strategies of a wide variety of beverages were catalogued to examine the prevalence of each strategy prior to a sweeping Chilean restriction of child-directed marketing aimed at reducing obesity-related disease among Chile's youth. Photographs of 1005 beverage packages were quantitatively content-analysed to code whether a variety of child-directed, health-oriented and other marketing strategies (e.g. sales promotions) were present on each product's FOP. Strategies were then analysed based on beverages' product category, total sugar, energy and tax status (beverages with added sugars are taxed at different rates). Photographs were taken in six urban supermarkets in Santiago, Chile, representing five different supermarket chains. Beverages using child-directed characters or nature/fruit references were higher in total sugar and beverages with child-directed characters or childhood/family references were higher in energy than beverages without these respective strategies. Of the beverages taxed at the highest rate (greatest amount of added sugars), 49 % used nutrition and health appeals and 80 % used nature or fruit appeals. Plain waters and plain milks were less likely than other selected product categories to use health-oriented appeals or multiple FOP strategies in combination. FOP marketing on beverages varied according to the nutritional quality of the product, with heavier use of health-oriented and child-directed strategies in less healthy products. Marketing activities warrant continued observation to evaluate how industry responds to new marketing restrictions as these restrictions are evaluated in the light of existing taxes and other regulatory efforts to improve diets and reduce obesity-related disease.
Ray Effect Mitigation Through Reference Frame Rotation
Tencer, John
2016-05-01
The discrete ordinates method is a popular and versatile technique for solving the radiative transport equation, a major drawback of which is the presence of ray effects. Mitigation of ray effects can yield significantly more accurate results and enhanced numerical stability for combined mode codes. Moreover, when ray effects are present, the solution is seen to be highly dependent upon the relative orientation of the geometry and the global reference frame. It is an undesirable property. A novel ray effect mitigation technique of averaging the computed solution for various reference frame orientations is proposed.
Spatial and physical frames of reference in positioning a limb.
Garrett, S R; Pagano, C; Austin, G; Turvey, M T
1998-10-01
Splints attached to the right forearm were used to rotate the forearm's physical reference frame, as defined by the eigenvectors of its inertia tensor, relative to its spatial reference frame. In two experiments, when subjects were required to orient the forearm parallel to, or at 45 degrees to, the environmental horizontal, they produced limb orientations that were systematically deflected from the forearm's longitudinal spatial axis in the direction of the forearm's physical axes. The position sense seems to be based on inertial eigenvectors rather than on joint angles or gravitational torques.
How Different EEG References Influence Sensor Level Functional Connectivity Graphs
Huang, Yunzhi; Zhang, Junpeng; Cui, Yuan; Yang, Gang; He, Ling; Liu, Qi; Yin, Guangfu
2017-01-01
Highlights: Hamming Distance is applied to distinguish the difference of functional connectivity networkThe orientations of sources are testified to influence the scalp Functional Connectivity Graph (FCG) from different references significantlyREST, the reference electrode standardization technique, is proved to have an overall stable and excellent performance in variable situations. The choice of an electroencephalograph (EEG) reference is a practical issue for the study of brain functional connectivity. To study how EEG reference influence functional connectivity estimation (FCE), this study compares the differences of FCE resulting from the different references such as REST (the reference electrode standardization technique), average reference (AR), linked mastoids (LM), and left mastoid references (LR). Simulations involve two parts. One is based on 300 dipolar pairs, which are located on the superficial cortex with a radial source direction. The other part is based on 20 dipolar pairs. In each pair, the dipoles have various orientation combinations. The relative error (RE) and Hamming distance (HD) between functional connectivity matrices of ideal recordings and that of recordings obtained with different references, are metrics to compare the differences of the scalp functional connectivity graph (FCG) derived from those two kinds of recordings. Lower RE and HD values imply more similarity between the two FCGs. Using the ideal recording (IR) as a standard, the results show that AR, LM and LR perform well only in specific conditions, i.e., AR performs stable when there is no upward component in sources' orientation. LR achieves desirable results when the sources' locations are away from left ear. LM achieves an indistinct difference with IR, i.e., when the distribution of source locations is symmetric along the line linking the two ears. However, REST not only achieves excellent performance for superficial and radial dipolar sources, but also achieves a stable and robust performance with variable source locations and orientations. Benefitting from the stable and robust performance of REST vs. other reference methods, REST might best recover the real FCG of EEG. Thus, REST based FCG may be a good candidate to compare the FCG of EEG based on different references from different labs. PMID:28725175
Burgmans, Mark Christiaan; den Harder, J Michiel; Meershoek, Philippa; van den Berg, Nynke S; Chan, Shaun Xavier Ju Min; van Leeuwen, Fijs W B; van Erkel, Arian R
2017-06-01
To determine the accuracy of automatic and manual co-registration methods for image fusion of three-dimensional computed tomography (CT) with real-time ultrasonography (US) for image-guided liver interventions. CT images of a skills phantom with liver lesions were acquired and co-registered to US using GE Logiq E9 navigation software. Manual co-registration was compared to automatic and semiautomatic co-registration using an active tracker. Also, manual point registration was compared to plane registration with and without an additional translation point. Finally, comparison was made between manual and automatic selection of reference points. In each experiment, accuracy of the co-registration method was determined by measurement of the residual displacement in phantom lesions by two independent observers. Mean displacements for a superficial and deep liver lesion were comparable after manual and semiautomatic co-registration: 2.4 and 2.0 mm versus 2.0 and 2.5 mm, respectively. Both methods were significantly better than automatic co-registration: 5.9 and 5.2 mm residual displacement (p < 0.001; p < 0.01). The accuracy of manual point registration was higher than that of plane registration, the latter being heavily dependent on accurate matching of axial CT and US images by the operator. Automatic reference point selection resulted in significantly lower registration accuracy compared to manual point selection despite lower root-mean-square deviation (RMSD) values. The accuracy of manual and semiautomatic co-registration is better than that of automatic co-registration. For manual co-registration using a plane, choosing the correct plane orientation is an essential first step in the registration process. Automatic reference point selection based on RMSD values is error-prone.
Wilderness Orientation Programs. AEE White Papers
ERIC Educational Resources Information Center
Association for Experiential Education (NJ1), 2011
2011-01-01
Wilderness orientation programs (sometimes referred to as outdoor orientation programs) use adventure programming for incoming college/university students to aid students' adjustment to college. These experiences usually occur in the days or weeks immediately prior to the first semester of the students' college coursework. They are typically…
Palgi, Yuval; Shrira, Amit
2015-01-01
Self-oriented adversity refers to traumatic events that primarily inflict the self, whereas other-oriented adversity refers to events that affect the self by primarily targeting others. The present study aimed to examine whether cultural background moderates the effects of self-oriented and other-oriented adversity on mental and physical health of older adults. Using longitudinal data from the Israeli component of the Survey of Health and Retirement, we focused on 370 Jews and 239 Arabs who reported their exposure to various adversities across the lifespan, and completed questionnaires regarding mental and physical health. Results showed that the effect of self-oriented adversity on health did not differ among Jews and Arabs. However, other-oriented adversity showed a stronger effect on Arabs’ mental and physical health than on Jews’ health. Our findings suggest that the accumulation of adverse events that affect the self by primarily targeting others may have a stronger impact in collectivist cultures than in individualist cultures. PMID:25961862
Yildirim, Funda; Carvalho, Joana; Cornelissen, Frans W
2018-01-01
Visual field or retinotopic mapping is one of the most frequently used paradigms in fMRI. It uses activity evoked by position-varying high luminance contrast visual patterns presented throughout the visual field for determining the spatial organization of cortical visual areas. While the advantage of using high luminance contrast is that it tends to drive a wide range of neural populations - thus resulting in high signal-to-noise BOLD responses - this may also be a limitation, especially for approaches that attempt to squeeze more information out of the BOLD response, such as population receptive field (pRF) mapping. In that case, more selective stimulation of a subset of neurons - despite reduced signals - could result in better characterization of pRF properties. Here, we used a second-order stimulus based on local differences in orientation texture - to which we refer as orientation contrast - to perform retinotopic mapping. Participants in our experiment viewed arrays of Gabor patches composed of a foreground (a bar) and a background. These could only be distinguished on the basis of a difference in patch orientation. In our analyses, we compare the pRF properties obtained using this new orientation contrast-based retinotopy (OCR) to those obtained using classic luminance contrast-based retinotopy (LCR). Specifically, in higher order cortical visual areas such as LO, our novel approach resulted in non-trivial reductions in estimated population receptive field size of around 30%. A set of control experiments confirms that the most plausible cause for this reduction is that OCR mainly drives neurons sensitive to orientation contrast. We discuss how OCR - by limiting receptive field scatter and reducing BOLD displacement - may result in more accurate pRF localization as well. Estimation of neuronal properties is crucial for interpreting cortical function. Therefore, we conclude that using our approach, it is possible to selectively target particular neuronal populations, opening the way to use pRF modeling to dissect the response properties of more clearly-defined neuronal populations in different visual areas. Copyright © 2017 Elsevier Inc. All rights reserved.
The reference frame of figure-ground assignment.
Vecera, Shaun P
2004-10-01
Figure-ground assignment involves determining which visual regions are foreground figures and which are backgrounds. Although figure-ground processes provide important inputs to high-level vision, little is known about the reference frame in which the figure's features and parts are defined. Computational approaches have suggested a retinally based, viewer-centered reference frame for figure-ground assignment, but figural assignment could also be computed on the basis of environmental regularities in an environmental reference frame. The present research used a newly discovered cue, lower region, to examine the reference frame of figure-ground assignment. Possible reference frames were misaligned by changing the orientation of viewers by having them tilt their heads (Experiments 1 and 2) or turn them upside down (Experiment 3). The results of these experiments indicated that figure-ground perception followed the orientation of the viewer, suggesting a viewer-centered reference frame for figure-ground assignment.
McGeorge, Christi R; Stone Carlson, Thomas; Farrell, Molly
2016-07-01
This study explored how negative beliefs toward lesbian, gay, and bisexual (LGB) individuals and LGB clinical competence influenced family therapists' beliefs and practices regarding referring based on the sexual orientation of the client. The sample consisted of 741 experienced clinicians. The results of this study indicated that the majority of the participants believe it is ethical to refer LGB clients; however, most had never made such a referral. Furthermore, participants who had referred based solely on the client's sexual orientation reported higher levels of negative beliefs toward LGB individuals and lower levels of LGB clinical competence. Finally, negative beliefs toward LGB persons not only predicted the practice of referring, but also the belief that it is ethical to refer an LGB client. © 2015 American Association for Marriage and Family Therapy.
Hwang, Jae Joon; Kim, Kee-Deog; Park, Hyok; Park, Chang Seo; Jeong, Ho-Gul
2014-01-01
Superimposition has been used as a method to evaluate the changes of orthodontic or orthopedic treatment in the dental field. With the introduction of cone beam CT (CBCT), evaluating 3 dimensional changes after treatment became possible by superimposition. 4 point plane orientation is one of the simplest ways to achieve superimposition of 3 dimensional images. To find factors influencing superimposition error of cephalometric landmarks by 4 point plane orientation method and to evaluate the reproducibility of cephalometric landmarks for analyzing superimposition error, 20 patients were analyzed who had normal skeletal and occlusal relationship and took CBCT for diagnosis of temporomandibular disorder. The nasion, sella turcica, basion and midpoint between the left and the right most posterior point of the lesser wing of sphenoidal bone were used to define a three-dimensional (3D) anatomical reference co-ordinate system. Another 15 reference cephalometric points were also determined three times in the same image. Reorientation error of each landmark could be explained substantially (23%) by linear regression model, which consists of 3 factors describing position of each landmark towards reference axes and locating error. 4 point plane orientation system may produce an amount of reorientation error that may vary according to the perpendicular distance between the landmark and the x-axis; the reorientation error also increases as the locating error and shift of reference axes viewed from each landmark increases. Therefore, in order to reduce the reorientation error, accuracy of all landmarks including the reference points is important. Construction of the regression model using reference points of greater precision is required for the clinical application of this model.
Bonds, A B
1989-01-01
Mechanisms supporting orientation selectivity of cat striate cortical cells were studied by stimulation with two superimposed sine-wave gratings of different orientations. One grating (base) generated a discharge of known amplitude which could be modified by the second grating (mask). Masks presented at nonoptimal orientations usually reduced the base-generated response, but the degree of reduction varied widely between cells. Cells with narrow orientation tuning tended to be more susceptible to mask presence than broadly tuned cells; similarly, simple cells generally showed more response reduction than did complex cells. The base and mask stimuli were drifted at different temporal frequencies which, in simple cells, permitted the identification of individual response components from each stimulus. This revealed that the reduction of the base response by the mask usually did not vary regularly with mask orientation, although response facilitation from the mask was orientation selective. In some sharply tuned simple cells, response reduction had clear local maxima near the limits of the cell's orientation-tuning function. Response reduction resulted from a nearly pure rightward shift of the response versus log contrast function. The lowest mask contrast yielding reduction was within 0.1-0.3 log unit of the lowest contrast effective for excitation. The temporal-frequency bandpass of the response-reduction mechanism resembled that of most cortical cells. The spatial-frequency bandpass was much broader than is typical for single cortical cells, spanning essentially the entire visual range of the cat. These findings are compatible with a model in which weak intrinsic orientation-selective excitation is enhanced in two stages: (1) control of threshold by nonorientation-selective inhibition that is continuously dependent on stimulus contrast; and (2) in the more narrowly tuned cells, orientation-selective inhibition that has local maxima serving to increase the slope of the orientation-tuning function.
Srinivasa, Narayan; Jiang, Qin
2013-01-01
This study describes a spiking model that self-organizes for stable formation and maintenance of orientation and ocular dominance maps in the visual cortex (V1). This self-organization process simulates three development phases: an early experience-independent phase, a late experience-independent phase and a subsequent refinement phase during which experience acts to shape the map properties. The ocular dominance maps that emerge accommodate the two sets of monocular inputs that arise from the lateral geniculate nucleus (LGN) to layer 4 of V1. The orientation selectivity maps that emerge feature well-developed iso-orientation domains and fractures. During the last two phases of development the orientation preferences at some locations appear to rotate continuously through ±180° along circular paths and referred to as pinwheel-like patterns but without any corresponding point discontinuities in the orientation gradient maps. The formation of these functional maps is driven by balanced excitatory and inhibitory currents that are established via synaptic plasticity based on spike timing for both excitatory and inhibitory synapses. The stability and maintenance of the formed maps with continuous synaptic plasticity is enabled by homeostasis caused by inhibitory plasticity. However, a prolonged exposure to repeated stimuli does alter the formed maps over time due to plasticity. The results from this study suggest that continuous synaptic plasticity in both excitatory neurons and interneurons could play a critical role in the formation, stability, and maintenance of functional maps in the cortex. PMID:23450808
ERIC Educational Resources Information Center
Hallman, Clemens L.; And Others
This teacher training monograph deals with value orientations of cultures in general and with specific reference to United States Culture. The first two sections discuss the conceptual issues of value orientation and give axiological definitions of the six clusters used to describe cultural orientation: self, the family, society, human nature,…
van Mier, Hanneke I
2016-01-01
When making two bars haptically parallel to each other, large deviations have been observed, most likely caused by the bias of a hand-centered egocentric reference frame. A consistent finding is that women show significantly larger deviations than men when performing this task. It has been suggested that this difference might be due to the fact that women are more egocentrically oriented than men or are less efficient in overcoming the egocentric bias of the hand. If this is indeed the case, reducing the bias of the egocentric reference frame should eliminate the above-mentioned gender difference. This was investigated in the current study. Sixty participants (30 men, 30 women) were instructed to haptically match (task HP) the orientation of a test bar with the dominant hand to the orientation of a reference bar that was perceived with the non-dominant hand. In a haptic visual task (task HV), in which only the reference bar and exploring hand were out of view, no motor response was required, but participants had to "match" the perceived orientation by verbally naming the parallel orientation that was read out on a test protractor. Both females and males performed better in the HV task than in the HP task. Significant gender effects were only found in the haptic parallelity task (HP), corroborating the idea that women perform at the same level as men when the egocentric bias of the hand is reduced.
ERIC Educational Resources Information Center
Malachowski, Colleen C.; Martin, Matthew M.; Vallade, Jessalyn I.
2013-01-01
Feedback orientations refer to students' perceptions of instructional feedback utility, retention, sensitivity, and confidentiality. In this paper, we report three studies that investigated the relationships among feedback orientations and communication traits. Specifically, we examined the associations among communication adaptation traits (Study…
ERIC Educational Resources Information Center
Du, Feng; Abrams, Richard A.
2012-01-01
To avoid sensory overload, people are able to selectively attend to a particular color or direction of motion while ignoring irrelevant stimuli that differ from the desired one. We show here for the first time that it is also possible to selectively attend to a specific line orientation--but with an important caveat: orientations that are…
Subcortical orientation biases explain orientation selectivity of visual cortical cells.
Vidyasagar, Trichur R; Jayakumar, Jaikishan; Lloyd, Errol; Levichkina, Ekaterina V
2015-04-01
The primary visual cortex of carnivores and primates shows an orderly progression of domains of neurons that are selective to a particular orientation of visual stimuli such as bars and gratings. We recorded from single-thalamic afferent fibers that terminate in these domains to address the issue whether the orientation sensitivity of these fibers could form the basis of the remarkable orientation selectivity exhibited by most cortical cells. We first performed optical imaging of intrinsic signals to obtain a map of orientation domains on the dorsal aspect of the anaesthetized cat's area 17. After confirming using electrophysiological recordings the orientation preferences of single neurons within one or two domains in each animal, we pharmacologically silenced the cortex to leave only the afferent terminals active. The inactivation of cortical neurons was achieved by the superfusion of either kainic acid or muscimol. Responses of single geniculate afferents were then recorded by the use of high impedance electrodes. We found that the orientation preferences of the afferents matched closely with those of the cells in the orientation domains that they terminated in (Pearson's r = 0.633, n = 22, P = 0.002). This suggests a possible subcortical origin for cortical orientation selectivity. © 2015 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.
Mechanical Twinning and Microstructures in Experimentally Stressed Quartzite
NASA Astrophysics Data System (ADS)
Minor, A.; Sintubin, M.; Wenk, H. R.; Rybacki, E.
2015-12-01
Since Dauphiné twins in quartz have been identified as a stress-related intracrystalline microstructure, several electron backscatter diffraction (EBSD) studies revealed that Dauphiné twins are present in naturally deformed quartz-bearing rocks in a wide range of tectono-metamorphic conditions. EBSD studies on experimentally stressed quartzite showed that crystals with particular crystallographic orientations contain many Dauphiné twin boundaries, while neighboring crystals with different orientations are largely free of twin boundaries. To understand the relationship between stress direction and orientation of Dauphiné twinned quartz crystals, a detailed EBSD study was performed on experimentally stressed quartzite samples and compared with an undeformed reference sample. We stressed 4 cylindrical samples in triaxial compression in a Paterson type gas deformation apparatus at GFZ Potsdam. Experimental conditions were 300MPa confining pressure, 500°C temperature and axial stresses of 145MPa, 250MPa and 460MPa for about 30 hours, resulting in a minor strain <0.04%. EBSD scans were obtained with a Zeiss Evo scanning electron microscope and TSL software at UC Berkeley. The EBSD maps show that Dauphiné twinning is present in the starting material as well as in experimentally stressed samples. Pole figures of the bulk orientation of the reference sample compared with stressed samples show a significant difference regarding the distribution for the r and z directions. The reference sample shows an indistinct maximum for r and z, whereas the stressed samples show a maximum for r poles and a minimum for z poles in the axial stress direction. EBSD scans of the reference and stressed samples were further analyzed manually to identify the orientations of single grains, which are free of twin boundaries and those, which contain twin boundaries. This analysis aims to quantify the relationship of crystal orientation and stress magnitude to initiate mechanical twinning.
Orientation-Selective Retinal Circuits in Vertebrates
Antinucci, Paride; Hindges, Robert
2018-01-01
Visual information is already processed in the retina before it is transmitted to higher visual centers in the brain. This includes the extraction of salient features from visual scenes, such as motion directionality or contrast, through neurons belonging to distinct neural circuits. Some retinal neurons are tuned to the orientation of elongated visual stimuli. Such ‘orientation-selective’ neurons are present in the retinae of most, if not all, vertebrate species analyzed to date, with species-specific differences in frequency and degree of tuning. In some cases, orientation-selective neurons have very stereotyped functional and morphological properties suggesting that they represent distinct cell types. In this review, we describe the retinal cell types underlying orientation selectivity found in various vertebrate species, and highlight their commonalities and differences. In addition, we discuss recent studies that revealed the cellular, synaptic and circuit mechanisms at the basis of retinal orientation selectivity. Finally, we outline the significance of these findings in shaping our current understanding of how this fundamental neural computation is implemented in the visual systems of vertebrates. PMID:29467629
Reprogramming of orientation columns in visual cortex: a domino effect
Bachatene, Lyes; Bharmauria, Vishal; Cattan, Sarah; Rouat, Jean; Molotchnikoff, Stéphane
2015-01-01
Cortical organization rests upon the fundamental principle that neurons sharing similar properties are co-located. In the visual cortex, neurons are organized into orientation columns. In a column, most neurons respond optimally to the same axis of an oriented edge, that is, the preferred orientation. This orientation selectivity is believed to be absolute in adulthood. However, in a fully mature brain, it has been established that neurons change their selectivity following sensory experience or visual adaptation. Here, we show that after applying an adapter away from the tested cells, neurons whose receptive fields were located remotely from the adapted site also exhibit a novel selectivity in spite of the fact that they were not adapted. These results indicate a robust reconfiguration and remapping of the orientation domains with respect to each other thus removing the possibility of an orientation hole in the new hypercolumn. These data suggest that orientation columns transcend anatomy, and are almost strictly functionally dynamic. PMID:25801392
Zhang, Jing; Zhang, Qingwen; Liu, Xiaoxia; Li, Zhen
2017-01-01
MicroRNAs (miRNAs) are a group of endogenous non-coding small RNAs that have critical regulatory functions in almost all known biological processes at the post-transcriptional level in a variety of organisms. The oriental fruit moth Grapholita molesta is one of the most serious pests in orchards worldwide and threatens the production of Rosacea fruits. In this study, a de novo small RNA library constructed from mixed stages of G. molesta was sequenced through Illumina sequencing platform and a total of 536 mature miRNAs consisting of 291 conserved and 245 novel miRNAs were identified. Most of the conserved and novel miRNAs were detected with moderate abundance. The miRNAs in the same cluster normally showed correlated expressional profiles. A comparative analysis of the 79 conserved miRNA families within 31 arthropod species indicated that these miRNA families were more conserved among insects and within orders of closer phylogenetic relationships. The KEGG pathway analysis and network prediction of target genes indicated that the complex composed of miRNAs, clock genes and developmental regulation genes may play vital roles to regulate the developmental circadian rhythm of G. molesta. Furthermore, based on the sRNA library of G. molesta, suitable reference genes were selected and validated for study of miRNA transcriptional profile in G. molesta under two biotic and six abiotic experimental conditions. This study systematically documented the miRNA profile in G. molesta, which could lay a foundation for further understanding of the regulatory roles of miRNAs in the development and metabolism in this pest and might also suggest clues to the development of genetic-based techniques for agricultural pest control. PMID:28158242
Development of orientation tuning in simple cells of primary visual cortex
Moore, Bartlett D.
2012-01-01
Orientation selectivity and its development are basic features of visual cortex. The original model of orientation selectivity proposes that elongated simple cell receptive fields are constructed from convergent input of an array of lateral geniculate nucleus neurons. However, orientation selectivity of simple cells in the visual cortex is generally greater than the linear contributions based on projections from spatial receptive field profiles. This implies that additional selectivity may arise from intracortical mechanisms. The hierarchical processing idea implies mainly linear connections, whereas cortical contributions are generally considered to be nonlinear. We have explored development of orientation selectivity in visual cortex with a focus on linear and nonlinear factors in a population of anesthetized 4-wk postnatal kittens and adult cats. Linear contributions are estimated from receptive field maps by which orientation tuning curves are generated and bandwidth is quantified. Nonlinear components are estimated as the magnitude of the power function relationship between responses measured from drifting sinusoidal gratings and those predicted from the spatial receptive field. Measured bandwidths for kittens are slightly larger than those in adults, whereas predicted bandwidths are substantially broader. These results suggest that relatively strong nonlinearities in early postnatal stages are substantially involved in the development of orientation tuning in visual cortex. PMID:22323631
Viswanathan, Sivaram; Jayakumar, Jaikishan; Vidyasagar, Trichur R
2011-01-01
Abstract Neurones of the mammalian primary visual cortex have the remarkable property of being selective for the orientation of visual contours. It has been controversial whether the selectivity arises from intracortical mechanisms, from the pattern of afferent connectivity from lateral geniculate nucleus (LGN) to cortical cells or from the sharpening of a bias that is already present in the responses of many geniculate cells. To investigate this, we employed a variation of an electrical stimulation protocol in the LGN that has been claimed to suppress intracortical inputs and isolate the raw geniculocortical input to a striate cortical cell. Such stimulation led to a sharpening of the orientation sensitivity of geniculate cells themselves and some broadening of cortical orientation selectivity. These findings are consistent with the idea that non-specific inhibition of the signals from LGN cells which exhibit an orientation bias can generate the sharp orientation selectivity of primary visual cortical cells. This obviates the need for an excitatory convergence from geniculate cells whose receptive fields are arranged along a row in visual space as in the classical model and provides a framework for orientation sensitivity originating in the retina and getting sharpened through inhibition at higher levels of the visual pathway. PMID:21486788
Sparky IntroChem: A Student-Oriented Introductory Chemistry Course.
ERIC Educational Resources Information Center
Butcher, David J.; Brandt, Paul F.; Norgaard, Nicholas J.; Atterholt, Cynthia A.; Salido, Arthur L.
2003-01-01
Describes an introductory chemistry course that incorporates student-oriented approaches such as inquiry and problem-based laboratories. Provides an overview of the modules. (Contains 16 references.) (DDR)
Ma, Ruijie; Lin, Xianming
2015-12-01
The problem based teaching (PBT) has been the main approach to the training in the universities o the world. Combined with the team oriented learning method, PBT will become the method available to the education in medical universities. In the paper, based on the common questions in teaching Jingluo Shuxue Xue (Science of Meridian and Acupoint), the concepts and characters of PBT and the team oriented learning method were analyzed. The implementation steps of PBT were set up in reference to the team oriented learning method. By quoting the original text in Beiji Qianjin Yaofang (Essential recipes for emergent use worth a thousand gold), the case analysis on "the thirteen devil points" was established with PBT.
Heterogeneity among Violence-Exposed Women: Applying Person-Oriented Research Methods
ERIC Educational Resources Information Center
Nurius, Paula S.; Macy, Rebecca J.
2008-01-01
Variability of experience and outcomes among violence-exposed people pose considerable challenges toward developing effective prevention and treatment protocols. To address these needs, the authors present an approach to research and a class of methodologies referred to as person oriented. Person-oriented tools support assessment of meaningful…
Teaching Orienteering. Second Edition.
ERIC Educational Resources Information Center
McNeill, Carol; Cory-Wright, Jean; Renfrew, Tom
The educational value provided by orienteering's blend of navigational and physical skills has given it a permanent place in the primary and secondary school curriculum in the United Kingdom. This book is a reference to orienteering for teachers, leaders, and coaches. It provides a "how to" approach to introducing and developing the…
Band registration of tuneable frame format hyperspectral UAV imagers in complex scenes
NASA Astrophysics Data System (ADS)
Honkavaara, Eija; Rosnell, Tomi; Oliveira, Raquel; Tommaselli, Antonio
2017-12-01
A recent revolution in miniaturised sensor technology has provided markets with novel hyperspectral imagers operating in the frame format principle. In the case of unmanned aerial vehicle (UAV) based remote sensing, the frame format technology is highly attractive in comparison to the commonly utilised pushbroom scanning technology, because it offers better stability and the possibility to capture stereoscopic data sets, bringing an opportunity for 3D hyperspectral object reconstruction. Tuneable filters are one of the approaches for capturing multi- or hyperspectral frame images. The individual bands are not aligned when operating a sensor based on tuneable filters from a mobile platform, such as UAV, because the full spectrum recording is carried out in the time-sequential principle. The objective of this investigation was to study the aspects of band registration of an imager based on tuneable filters and to develop a rigorous and efficient approach for band registration in complex 3D scenes, such as forests. The method first determines the orientations of selected reference bands and reconstructs the 3D scene using structure-from-motion and dense image matching technologies. The bands, without orientation, are then matched to the oriented bands accounting the 3D scene to provide exterior orientations, and afterwards, hyperspectral orthomosaics, or hyperspectral point clouds, are calculated. The uncertainty aspects of the novel approach were studied. An empirical assessment was carried out in a forested environment using hyperspectral images captured with a hyperspectral 2D frame format camera, based on a tuneable Fabry-Pérot interferometer (FPI) on board a multicopter and supported by a high spatial resolution consumer colour camera. A theoretical assessment showed that the method was capable of providing band registration accuracy better than 0.5-pixel size. The empirical assessment proved the performance and showed that, with the novel method, most parts of the band misalignments were less than the pixel size. Furthermore, it was shown that the performance of the band alignment was dependent on the spatial distance from the reference band.
Effects of norm referent salience on young people's dietary orientation.
Tarrant, Mark; Khan, Sammyh S; Qin, Qi
2015-02-01
We examined the effects of making salient different norm referents on young people's dietary orientation. Participants were exposed to a referent who was either of similar age to themselves or older before reporting their normative beliefs, attitudes and intentions concerning dietary behavior. As predicted, exposure to the older referent was associated with stronger perceptions that eating five portions of fruit and vegetables each day was normative. Compared to those exposed to the same-age referent, participants exposed to the older referent reported more positive attitudes towards eating "five-a-day" and stronger intentions to do so over the coming week. Referent salience was also associated with a behavioral outcome, with those participants exposed to the older referent more likely to take a piece of fruit upon completion of the study (OR: 4.97, 95% CI: 1.39-17.82). The implications of these findings for norms-based interventions for changing dietary behavior are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
Mantzouranis, Gregory; Zimmermann, Gregoire; Mahaim, Elodie Biermann; Favez, Nicolas
2012-01-01
Psychological control refers to parental behaviors that intrude on the psychological and emotional development of the child. In 2010, Soenens et al. proposed a distinction between two domain-specific expressions of psychological control, that is, Dependency-oriented Psychological Control (DPC) and Achievement-oriented Psychological Control (APC).…
Gharat, Amol; Baker, Curtis L
2017-01-25
Many of the neurons in early visual cortex are selective for the orientation of boundaries defined by first-order cues (luminance) as well as second-order cues (contrast, texture). The neural circuit mechanism underlying this selectivity is still unclear, but some studies have proposed that it emerges from spatial nonlinearities of subcortical Y cells. To understand how inputs from the Y-cell pathway might be pooled to generate cue-invariant receptive fields, we recorded visual responses from single neurons in cat Area 18 using linear multielectrode arrays. We measured responses to drifting and contrast-reversing luminance gratings as well as contrast modulation gratings. We found that a large fraction of these neurons have nonoriented responses to gratings, similar to those of subcortical Y cells: they respond at the second harmonic (F2) to high-spatial frequency contrast-reversing gratings and at the first harmonic (F1) to low-spatial frequency drifting gratings ("Y-cell signature"). For a given neuron, spatial frequency tuning for linear (F1) and nonlinear (F2) responses is quite distinct, similar to orientation-selective cue-invariant neurons. Also, these neurons respond to contrast modulation gratings with selectivity for the carrier (texture) spatial frequency and, in some cases, orientation. Their receptive field properties suggest that they could serve as building blocks for orientation-selective cue-invariant neurons. We propose a circuit model that combines ON- and OFF-center cortical Y-like cells in an unbalanced push-pull manner to generate orientation-selective, cue-invariant receptive fields. A significant fraction of neurons in early visual cortex have specialized receptive fields that allow them to selectively respond to the orientation of boundaries that are invariant to the cue (luminance, contrast, texture, motion) that defines them. However, the neural mechanism to construct such versatile receptive fields remains unclear. Using multielectrode recording, we found a large fraction of neurons in early visual cortex with receptive fields not selective for orientation that have spatial nonlinearities like those of subcortical Y cells. These are strong candidates for building cue-invariant orientation-selective neurons; we present a neural circuit model that pools such neurons in an imbalanced "push-pull" manner, to generate orientation-selective cue-invariant receptive fields. Copyright © 2017 the authors 0270-6474/17/370998-16$15.00/0.
Buffer layers for coated conductors
Stan, Liliana [Los Alamos, NM; Jia, Quanxi [Los Alamos, NM; Foltyn, Stephen R [Los Alamos, NM
2011-08-23
A composite structure is provided including a base substrate, an IBAD oriented material upon the base substrate, and a cubic metal oxide material selected from the group consisting of rare earth zirconates and rare earth hafnates upon the IBAD oriented material. Additionally, an article is provided including a base substrate, an IBAD oriented material upon the base substrate, a cubic metal oxide material selected from the group consisting of rare earth zirconates and rare earth hafnates upon the IBAD oriented material, and a thick film upon the cubic metal oxide material. Finally, a superconducting article is provided including a base substrate, an IBAD oriented material upon the base substrate, a cubic metal oxide material selected from the group consisting of rare earth zirconates and rare earth hafnates upon the IBAD oriented material, and an yttrium barium copper oxide material upon the cubic metal oxide material.
Bibliography. Computer-Oriented Projects, 1987.
ERIC Educational Resources Information Center
Smith, Richard L., Comp.
1988-01-01
Provides an annotated list of references on computer-oriented projects. Includes information on computers; hands-on versus simulations; games; instruction; students' attitudes and learning styles; artificial intelligence; tutoring; and application of spreadsheets. (RT)
NASA Astrophysics Data System (ADS)
Brunner, Robert
2014-04-01
In a series of two contributions, decisive business-related aspects of the current process status to transfer research results on diffractive optical elements (DOEs) into commercial solutions are discussed. In part I, the focus was on the patent landscape. Here, in part II, market estimations concerning DOEs for selected applications are presented, comprising classical spectroscopic gratings, security features on banknotes, DOEs for high-end applications, e.g., for the semiconductor manufacturing market and diffractive intra-ocular lenses. The derived market sizes are referred to the optical elements, itself, rather than to the enabled instruments. The estimated market volumes are mainly addressed to scientifically and technologically oriented optical engineers to serve as a rough classification of the commercial dimensions of DOEs in the different market segments and do not claim to be exhaustive.
Perceptual Learning Selectively Refines Orientation Representations in Early Visual Cortex
Jehee, Janneke F.M.; Ling, Sam; Swisher, Jascha D.; van Bergen, Ruben S.; Tong, Frank
2013-01-01
Although practice has long been known to improve perceptual performance, the neural basis of this improvement in humans remains unclear. Using fMRI in conjunction with a novel signal detection-based analysis, we show that extensive practice selectively enhances the neural representation of trained orientations in the human visual cortex. Twelve observers practiced discriminating small changes in the orientation of a laterally presented grating over 20 or more daily one-hour training sessions. Training on average led to a two-fold improvement in discrimination sensitivity, specific to the trained orientation and the trained location, with minimal improvement found for untrained orthogonal orientations or for orientations presented in the untrained hemifield. We measured the strength of orientation-selective responses in individual voxels in early visual areas (V1–V4) using signal detection measures, both pre- and post-training. Although the overall amplitude of the BOLD response was no greater after training, practice nonetheless specifically enhanced the neural representation of the trained orientation at the trained location. This training-specific enhancement of orientation-selective responses was observed in the primary visual cortex (V1) as well as higher extrastriate visual areas V2–V4, and moreover, reliably predicted individual differences in the behavioral effects of perceptual learning. These results demonstrate that extensive training can lead to targeted functional reorganization of the human visual cortex, refining the cortical representation of behaviorally relevant information. PMID:23175828
Perceptual learning selectively refines orientation representations in early visual cortex.
Jehee, Janneke F M; Ling, Sam; Swisher, Jascha D; van Bergen, Ruben S; Tong, Frank
2012-11-21
Although practice has long been known to improve perceptual performance, the neural basis of this improvement in humans remains unclear. Using fMRI in conjunction with a novel signal detection-based analysis, we show that extensive practice selectively enhances the neural representation of trained orientations in the human visual cortex. Twelve observers practiced discriminating small changes in the orientation of a laterally presented grating over 20 or more daily 1 h training sessions. Training on average led to a twofold improvement in discrimination sensitivity, specific to the trained orientation and the trained location, with minimal improvement found for untrained orthogonal orientations or for orientations presented in the untrained hemifield. We measured the strength of orientation-selective responses in individual voxels in early visual areas (V1-V4) using signal detection measures, both before and after training. Although the overall amplitude of the BOLD response was no greater after training, practice nonetheless specifically enhanced the neural representation of the trained orientation at the trained location. This training-specific enhancement of orientation-selective responses was observed in the primary visual cortex (V1) as well as higher extrastriate visual areas V2-V4, and moreover, reliably predicted individual differences in the behavioral effects of perceptual learning. These results demonstrate that extensive training can lead to targeted functional reorganization of the human visual cortex, refining the cortical representation of behaviorally relevant information.
Lateral Spread of Orientation Selectivity in V1 is Controlled by Intracortical Cooperativity
Chavane, Frédéric; Sharon, Dahlia; Jancke, Dirk; Marre, Olivier; Frégnac, Yves; Grinvald, Amiram
2011-01-01
Neurons in the primary visual cortex receive subliminal information originating from the periphery of their receptive fields (RF) through a variety of cortical connections. In the cat primary visual cortex, long-range horizontal axons have been reported to preferentially bind to distant columns of similar orientation preferences, whereas feedback connections from higher visual areas provide a more diverse functional input. To understand the role of these lateral interactions, it is crucial to characterize their effective functional connectivity and tuning properties. However, the overall functional impact of cortical lateral connections, whatever their anatomical origin, is unknown since it has never been directly characterized. Using direct measurements of postsynaptic integration in cat areas 17 and 18, we performed multi-scale assessments of the functional impact of visually driven lateral networks. Voltage-sensitive dye imaging showed that local oriented stimuli evoke an orientation-selective activity that remains confined to the cortical feedforward imprint of the stimulus. Beyond a distance of one hypercolumn, the lateral spread of cortical activity gradually lost its orientation preference approximated as an exponential with a space constant of about 1 mm. Intracellular recordings showed that this loss of orientation selectivity arises from the diversity of converging synaptic input patterns originating from outside the classical RF. In contrast, when the stimulus size was increased, we observed orientation-selective spread of activation beyond the feedforward imprint. We conclude that stimulus-induced cooperativity enhances the long-range orientation-selective spread. PMID:21629708
Hand placement near the visual stimulus improves orientation selectivity in V2 neurons
Sergio, Lauren E.; Crawford, J. Douglas; Fallah, Mazyar
2015-01-01
Often, the brain receives more sensory input than it can process simultaneously. Spatial attention helps overcome this limitation by preferentially processing input from a behaviorally-relevant location. Recent neuropsychological and psychophysical studies suggest that attention is deployed to near-hand space much like how the oculomotor system can deploy attention to an upcoming gaze position. Here we provide the first neuronal evidence that the presence of a nearby hand enhances orientation selectivity in early visual processing area V2. When the hand was placed outside the receptive field, responses to the preferred orientation were significantly enhanced without a corresponding significant increase at the orthogonal orientation. Consequently, there was also a significant sharpening of orientation tuning. In addition, the presence of the hand reduced neuronal response variability. These results indicate that attention is automatically deployed to the space around a hand, improving orientation selectivity. Importantly, this appears to be optimal for motor control of the hand, as opposed to oculomotor mechanisms which enhance responses without sharpening orientation selectivity. Effector-based mechanisms for visual enhancement thus support not only the spatiotemporal dissociation of gaze and reach, but also the optimization of vision for their separate requirements for guiding movements. PMID:25717165
Selective enhancement of orientation tuning before saccades.
Ohl, Sven; Kuper, Clara; Rolfs, Martin
2017-11-01
Saccadic eye movements cause a rapid sweep of the visual image across the retina and bring the saccade's target into high-acuity foveal vision. Even before saccade onset, visual processing is selectively prioritized at the saccade target. To determine how this presaccadic attention shift exerts its influence on visual selection, we compare the dynamics of perceptual tuning curves before movement onset at the saccade target and in the opposite hemifield. Participants monitored a 30-Hz sequence of randomly oriented gratings for a target orientation. Combining a reverse correlation technique previously used to study orientation tuning in neurons and general additive mixed modeling, we found that perceptual reports were tuned to the target orientation. The gain of orientation tuning increased markedly within the last 100 ms before saccade onset. In addition, we observed finer orientation tuning right before saccade onset. This increase in gain and tuning occurred at the saccade target location and was not observed at the incongruent location in the opposite hemifield. The present findings suggest, therefore, that presaccadic attention exerts its influence on vision in a spatially and feature-selective manner, enhancing performance and sharpening feature tuning at the future gaze location before the eyes start moving.
Tilt aftereffect following adaptation to translational Glass patterns
Pavan, Andrea; Hocketstaller, Johanna; Contillo, Adriano; Greenlee, Mark W.
2016-01-01
Glass patterns (GPs) consist of randomly distributed dot pairs (dipoles) whose orientations are determined by specific geometric transforms. We assessed whether adaptation to stationary oriented translational GPs suppresses the activity of orientation selective detectors producing a tilt aftereffect (TAE). The results showed that adaptation to GPs produces a TAE similar to that reported in previous studies, though reduced in amplitude. This suggests the involvement of orientation selective mechanisms. We also measured the interocular transfer (IOT) of the GP-induced TAE and found an almost complete IOT, indicating the involvement of orientation selective and binocularly driven units. In additional experiments, we assessed the role of attention in TAE from GPs. The results showed that distraction during adaptation similarly modulates the TAE after adapting to both GPs and gratings. Moreover, in the case of GPs, distraction is likely to interfere with the adaptation process rather than with the spatial summation of local dipoles. We conclude that TAE from GPs possibly relies on visual processing levels in which the global orientation of GPs has been encoded by neurons that are mostly binocularly driven, orientation selective and whose adaptation-related neural activity is strongly modulated by attention. PMID:27005949
THE LIMITED EFFECT OF COINCIDENT ORIENTATION ON THE CHOICE OF INTRINSIC AXIS (.).
Li, Jing; Su, Wei
2015-06-01
The allocentric system computes and represents general object-to-object spatial relationships to provide a spatial frame of reference other than the egocentric system. The intrinsic frame-of-reference system theory, which suggests people learn the locations of objects based upon an intrinsic axis, is important in research about the allocentric system. The purpose of the current study was to determine whether the effect of coincident orientation on the choice of intrinsic axis was limited. Two groups of participants (24 men, 24 women; M age = 24 yr., SD = 2) encoded different spatial layouts in which the objects shared the coincident orientation of 315° and 225° separately at learning perspective (0°). The response pattern of partial-scene-recognition task following learning reflected different strategies for choosing the intrinsic axis under different conditions. Under the 315° object-orientation condition, the objects' coincident orientation was as important as the symmetric axis in the choice of the intrinsic axis. However, participants were more likely to choose the symmetric axis as the intrinsic axis under the 225° object-orientation condition. The results suggest the effect of coincident orientation on the choice of intrinsic axis is limited.
Accessibility versus Accuracy in Retrieving Spatial Memory: Evidence for Suboptimal Assumed Headings
ERIC Educational Resources Information Center
Yerramsetti, Ashok; Marchette, Steven A.; Shelton, Amy L.
2013-01-01
Orientation dependence in spatial memory has often been interpreted in terms of accessibility: Object locations are encoded relative to a reference orientation that affords the most accurate access to spatial memory. An open question, however, is whether people naturally use this "preferred" orientation whenever recalling the space. We…
Palgi, Yuval; Shrira, Amit
2016-03-01
Self-oriented adversity refers to traumatic events that primarily inflict the self, whereas other-oriented adversity refers to events that affect the self by primarily targeting others. The present study aimed to examine whether cultural background moderates the effects of self-oriented and other-oriented adversity on mental and physical health of older adults. Using longitudinal data from the Israeli component of the Survey of Health and Retirement, we focused on 370 Jews and 239 Arabs who reported their exposure to various adversities across the life span, and completed questionnaires regarding mental and physical health. Results showed that the effect of self-oriented adversity on health did not differ among Jews and Arabs. However, other-oriented adversity showed a stronger effect on Arabs' mental and physical health than on Jews' health. Our findings suggest that the accumulation of adverse events that affect the self by primarily targeting others may have a stronger impact in collectivist cultures than in individualist cultures. (c) 2016 APA, all rights reserved).
Perception of Upright: Multisensory Convergence and the Role of Temporo-Parietal Cortex
Kheradmand, Amir; Winnick, Ariel
2017-01-01
We inherently maintain a stable perception of the world despite frequent changes in the head, eye, and body positions. Such “orientation constancy” is a prerequisite for coherent spatial perception and sensorimotor planning. As a multimodal sensory reference, perception of upright represents neural processes that subserve orientation constancy through integration of sensory information encoding the eye, head, and body positions. Although perception of upright is distinct from perception of body orientation, they share similar neural substrates within the cerebral cortical networks involved in perception of spatial orientation. These cortical networks, mainly within the temporo-parietal junction, are crucial for multisensory processing and integration that generate sensory reference frames for coherent perception of self-position and extrapersonal space transformations. In this review, we focus on these neural mechanisms and discuss (i) neurobehavioral aspects of orientation constancy, (ii) sensory models that address the neurophysiology underlying perception of upright, and (iii) the current evidence for the role of cerebral cortex in perception of upright and orientation constancy, including findings from the neurological disorders that affect cortical function. PMID:29118736
Cognitive indicators of social anxiety in youth: a structural equation analysis.
Rudy, Brittany M; Davis, Thompson E; Matthews, Russell A
2014-01-01
Previous studies have demonstrated significant relationships among various cognitive variables such as negative cognition, self-efficacy, and social anxiety. Unfortunately, few studies focus on the role of cognition among youth, and researchers often fail to use domain-specific measures when examining cognitive variables. Therefore, the purpose of the present study was to examine domain-specific cognitive variables (i.e., socially oriented negative self-referent cognition and social self-efficacy) and their relationships to social anxiety in children and adolescents using structural equation modeling techniques. A community sample of children and adolescents (n=245; 55.9% female; 83.3% Caucasian, 9.4% African American, 2% Asian, 2% Hispanic, 2% "other," and 1.2% not reported) completed questionnaires assessing social cognition and social anxiety symptomology. Three latent variables were created to examine the constructs of socially oriented negative self-referent cognition (as measured by the SONAS scale), social self-efficacy (as measured by the SEQSS-C), and social anxiety (as measured by the SPAI-C and the Brief SA). The resulting measurement model of latent variables fit the data well. Additionally, consistent with the study hypothesis, results indicated that social self-efficacy likely mediates the relationship between socially oriented negative self-referent cognition and social anxiety, and socially oriented negative self-referent cognition yields significant direct and indirect effects on social anxiety. These findings indicate that socially oriented negative cognitions are associated with youth's beliefs about social abilities and the experience of social anxiety. Future directions for research and study limitations, including use of cross-sectional data, are discussed. © 2013.
Farin, E
2008-04-01
Measuring the results of rehabilitation interventions presents a number of issues regarding content and method, two of which have been selected for discussion in view of the findings of current research--the significance of patient orientation and the relation to the International Classification of Functioning, Disability and Health, ICF. Compilation of patients' treatment goals, expectations and preferences, patient participation in the development of assessment instruments, compilation of patients' evaluations of treatment results and consideration of the subjectivity of the physician as well as interaction between patient and physician were discussed with respect to involving patients in measuring results. The ICF is a terminology system presenting a uniform international classification for describing health conditions that could assume the function of a common language for the members of various occupations involved in medical rehabilitation. Orienting the measurement of results to the ICF is an obvious next step. This can promote patient orientation, as the categories used by the ICF--in particular for the domains of activities and participation--are formulated in terms relevant to daily routine and are thus pertinent to the patients' lifestyle. The consequences resulting from this overview concern future research needs on the one hand, and on the other hand tips for carrying out a patient-oriented, ICF-based measurement of results. The need for research becomes especially clear regarding the measurement of results based on patient preferences, the determination of the participation relevance perceived by the patient as a criterion for "patient significance" (analogous to "clinical significance"), the integration and weighting of patient and physician assessments of success, the consideration of physicians' subjective concepts and patients' communication preferences, and the design of new, ICF-oriented assessment instruments.
Gravity orientation tuning in macaque anterior thalamus.
Laurens, Jean; Kim, Byounghoon; Dickman, J David; Angelaki, Dora E
2016-12-01
Gravity may provide a ubiquitous allocentric reference to the brain's spatial orientation circuits. Here we describe neurons in the macaque anterior thalamus tuned to pitch and roll orientation relative to gravity, independently of visual landmarks. We show that individual cells exhibit two-dimensional tuning curves, with peak firing rates at a preferred vertical orientation. These results identify a thalamic pathway for gravity cues to influence perception, action and spatial cognition.
Face inversion and acquired prosopagnosia reduce the size of the perceptual field of view.
Van Belle, Goedele; Lefèvre, Philippe; Rossion, Bruno
2015-03-01
Using a gaze-contingent morphing approach, we asked human observers to choose one of two faces that best matched the identity of a target face: one face corresponded to the reference face's fixated part only (e.g., one eye), the other corresponded to the unfixated area of the reference face. The face corresponding to the fixated part was selected significantly more frequently in the inverted than in the upright orientation. This observation provides evidence that face inversion reduces an observer's perceptual field of view, even when both upright and inverted faces are displayed at full view and there is no performance difference between these conditions. It rules out an account of the drop of performance for inverted faces--one of the most robust effects in experimental psychology--in terms of a mere difference in local processing efficiency. A brain-damaged patient with pure prosopagnosia, viewing only upright faces, systematically selected the face corresponding to the fixated part, as if her perceptual field was reduced relative to normal observers. Altogether, these observations indicate that the absence of visual knowledge reduces the perceptual field of view, supporting an indirect view of visual perception. Copyright © 2014 Elsevier B.V. All rights reserved.
On the computer analysis of structures and mechanical systems
NASA Technical Reports Server (NTRS)
Bennett, B. E.
1984-01-01
The governing equations for the analysis of open branch-chain mechanical systems are developed in a form suitable for implementation in a general purpose finite element computer program. Lagrange's form of d'Alembert's principle is used to derive the system mass matrix and force vector. The generalized coordinates are selected as the unconstrained relative degrees of freedom giving the position and orientation of each slave link with respect to their master link. Each slave link may have from zero to six degrees of freedom relative to the reference frames of its master link. A strategy for automatic generation of the system mass matrix and force vector is described.
Experimental investigation of an astronaut maneuvering scheme.
NASA Technical Reports Server (NTRS)
Kane, T. R.; Headrick, M. R.; Yatteau, J. D.
1972-01-01
A new concept for astronaut maneuvering in space is proposed, and an experimental study undertaken to test this concept is described. The series of experiments performed appear to promise advantages over previously proposed schemes in terms of propellant economy, system weight, reliability, and safety. The simulation tests established the feasibility of the proposed maneuvering concept by showing that test subjects were able to place their bodies sufficiently near the reference position to avoid excessive angular momentum build-up; no difficulties were encountered in selecting self-rotation maneuvers suitable for effecting desired changes in orientation; and the execution of these maneuvers produced predicted reorientations without tiring the test subject significantly.
Orientation selective deep brain stimulation
NASA Astrophysics Data System (ADS)
Lehto, Lauri J.; Slopsema, Julia P.; Johnson, Matthew D.; Shatillo, Artem; Teplitzky, Benjamin A.; Utecht, Lynn; Adriany, Gregor; Mangia, Silvia; Sierra, Alejandra; Low, Walter C.; Gröhn, Olli; Michaeli, Shalom
2017-02-01
Objective. Target selectivity of deep brain stimulation (DBS) therapy is critical, as the precise locus and pattern of the stimulation dictates the degree to which desired treatment responses are achieved and adverse side effects are avoided. There is a clear clinical need to improve DBS technology beyond currently available stimulation steering and shaping approaches. We introduce orientation selective neural stimulation as a concept to increase the specificity of target selection in DBS. Approach. This concept, which involves orienting the electric field along an axonal pathway, was tested in the corpus callosum of the rat brain by freely controlling the direction of the electric field on a plane using a three-electrode bundle, and monitoring the response of the neurons using functional magnetic resonance imaging (fMRI). Computational models were developed to further analyze axonal excitability for varied electric field orientation. Main results. Our results demonstrated that the strongest fMRI response was observed when the electric field was oriented parallel to the axons, while almost no response was detected with the perpendicular orientation of the electric field relative to the primary fiber tract. These results were confirmed by computational models of the experimental paradigm quantifying the activation of radially distributed axons while varying the primary direction of the electric field. Significance. The described strategies identify a new course for selective neuromodulation paradigms in DBS based on axonal fiber orientation.
NASA Astrophysics Data System (ADS)
Wang, Xiaohui; Foos, David H.; Doran, James; Rogers, Michael K.
2004-05-01
Full-leg and full-spine imaging with standard computed radiography (CR) systems requires several cassettes/storage phosphor screens to be placed in a staggered arrangement and exposed simultaneously to achieve an increased imaging area. A method has been developed that can automatically and accurately stitch the acquired sub-images without relying on any external reference markers. It can detect and correct the order, orientation, and overlap arrangement of the subimages for stitching. The automatic determination of the order, orientation, and overlap arrangement of the sub-images consists of (1) constructing a hypothesis list that includes all cassette/screen arrangements, (2) refining hypotheses based on a set of rules derived from imaging physics, (3) correlating each consecutive sub-image pair in each hypothesis and establishing an overall figure-of-merit, (4) selecting the hypothesis of maximum figure-of-merit. The stitching process requires the CR reader to over scan each CR screen so that the screen edges are completely visible in the acquired sub-images. The rotational displacement and vertical displacement between two consecutive sub-images are calculated by matching the orientation and location of the screen edge in the front image and its corresponding shadow in the back image. The horizontal displacement is estimated by maximizing the correlation function between the two image sections in the overlap region. Accordingly, the two images are stitched together. This process is repeated for the newly stitched composite image and the next consecutive sub-image until a full-image composite is created. The method has been evaluated in both phantom experiments and clinical studies. The standard deviation of image misregistration is below one image pixel.
Statistics of natural scenes and cortical color processing.
Cecchi, Guillermo A; Rao, A Ravishankar; Xiao, Youping; Kaplan, Ehud
2010-09-01
We investigate the spatial correlations of orientation and color information in natural images. We find that the correlation of orientation information falls off rapidly with increasing distance, while color information is more highly correlated over longer distances. We show that orientation and color information are statistically independent in natural images and that the spatial correlation of jointly encoded orientation and color information decays faster than that of color alone. Our findings suggest that: (a) orientation and color information should be processed in separate channels and (b) the organization of cortical color and orientation selectivity at low spatial frequencies is a reflection of the cortical adaptation to the statistical structure of the visual world. These findings are in agreement with biological observations, as form and color are thought to be represented by different classes of neurons in the primary visual cortex, and the receptive fields of color-selective neurons are larger than those of orientation-selective neurons. The agreement between our findings and biological observations supports the ecological theory of perception.
The Determination of Earth Orientation by VLBI and GNSS: Principles and Results
NASA Astrophysics Data System (ADS)
Capitaine, Nicole
2017-10-01
The Earth Orientation Parameters (EOP) connect the International Terrestrial Reference System (ITRS) to the Geocentric Celestial Reference System (GCRS). These parameters, i.e., Universal Time, UT1, and pole coordinates in the ITRS and in the GCRS, describe the irregularities of the Earth's rotation. They are mainly determined by two modern astro-geodetic techniques, VLBI (Very Long Baseline Radio Interferometry) on extragalactic radio sources, which is used to realize and maintain the International Celestial Reference System (ICRS), and Global Navigation Satellite System (GNSS), especially GPS (Global Positioning System), which has an important contribution to the realization of the ITRS. The aim of this presentation is twofold: to present the modern bases for the consider- ation of Earth orientation and to discuss how the principles of VLBI and GPS give access to the measure of different components of the EOP variations, especially UT1. The accuracy that can be achieved is based on the improved concepts, definitions, and models that have been adopted by IAU/IUGG resolutions on reference systems and Earth's rotation, as well as on the refined strategy of the observations.
Effect of gravito-inertial cues on the coding of orientation in pre-attentive vision.
Stivalet, P; Marendaz, C; Barraclough, L; Mourareau, C
1995-01-01
To see if the spatial reference frame used by pre-attentive vision is specified in a retino-centered frame or in a reference frame integrating visual and nonvisual information (vestibular and somatosensory), subjects were centrifuged in a non-pendular cabin and were asked to search for a target distinguishable from distractors by difference in orientation (Treisman's "pop-out" paradigm [1]). In a control condition, in which subjects were sitting immobilized but not centrifuged, this task gave an asymmetric search pattern: Search was rapid and pre-attentional except when the target was aligned with the horizontal retinal/head axis, in which case search was slow and attentional (2). Results using a centrifuge showed that slow/serial search patterns were obtained when the target was aligned with the subjective horizontal axis (and not with the horizontal retinal/head axis). These data suggest that a multisensory reference frame is used in pre-attentive vision. The results are interpreted in terms of Riccio and Stoffregen's "ecological theory" of orientation in which the vertical and horizontal axes constitute independent reference frames (3).
Visualization of the IMIA Yearbook of Medical Informatics Publications over the Last 25 Years
Tam-Tham, H.; Minty, E. P.
2016-01-01
Summary Background The last 25 years have been a period of innovation in the area of medical informatics. The International Medical Informatics Association (IMIA) has published, every year for the last quarter century, the Yearbook of Medical Informatics, collating selected papers from various journals in an attempt to provide a summary of the academic medical informatics literature. The objective of this paper is to visualize the evolution of the medical informatics field over the last 25 years according to the frequency of word occurrences in the papers published in the IMIA Yearbook of Medical Informatics. Methods A literature review was conducted examining the IMIA Yearbook of Medical Informatics between 1992 and 2015. These references were collated into a reference manager application to examine the literature using keyword searches, word clouds, and topic clustering. The data was considered in its entirety, as well as segregated into 3 time periods to examine the evolution of main trends over time. Several methods were used, including word clouds, cluster maps, and custom developed web-based information dashboards. Results The literature search resulted in a total of 1210 references published in the Yearbook, of which 213 references were excluded, resulting in 997 references for visualization. Overall, we found that publications were more technical and methods-oriented between 1992 and 1999; more clinically and patient-oriented between 2000 and 2009; and noted the emergence of “big data”, decision support, and global health in the past decade between 2010 and 2015. Dashboards were additionally created to show individual reference data, as well as, aggregated information. Conclusion Medical informatics is a vast and expanding area with new methods and technologies being researched, implemented, and evaluated. Determining visualization approaches that enhance our understanding of literature is an active area of research, and like medical informatics, is constantly evolving as new software and algorithms are developed. This paper examined several approaches for visualizing the medical informatics literature to show historical trends, associations, and aggregated summarized information to illustrate the state and changes in the IMIA Yearbook publications over the last quarter century. PMID:27362591
Visualization of the IMIA Yearbook of Medical Informatics Publications over the Last 25 Years.
Yergens, D W; Tam-Tham, H; Minty, E P
2016-06-30
The last 25 years have been a period of innovation in the area of medical informatics. The International Medical Informatics Association (IMIA) has published, every year for the last quarter century, the Yearbook of Medical Informatics, collating selected papers from various journals in an attempt to provide a summary of the academic medical informatics literature. The objective of this paper is to visualize the evolution of the medical informatics field over the last 25 years according to the frequency of word occurrences in the papers published in the IMIA Yearbook of Medical Informatics. A literature review was conducted examining the IMIA Yearbook of Medical Informatics between 1992 and 2015. These references were collated into a reference manager application to examine the literature using keyword searches, word clouds, and topic clustering. The data was considered in its entirety, as well as segregated into 3 time periods to examine the evolution of main trends over time. Several methods were used, including word clouds, cluster maps, and custom developed web-based information dashboards. The literature search resulted in a total of 1210 references published in the Yearbook, of which 213 references were excluded, resulting in 997 references for visualization. Overall, we found that publications were more technical and methods-oriented between 1992 and 1999; more clinically and patient-oriented between 2000 and 2009; and noted the emergence of "big data", decision support, and global health in the past decade between 2010 and 2015. Dashboards were additionally created to show individual reference data, as well as, aggregated information. Medical informatics is a vast and expanding area with new methods and technologies being researched, implemented, and evaluated. Determining visualization approaches that enhance our understanding of literature is an active area of research, and like medical informatics, is constantly evolving as new software and algorithms are developed. This paper examined several approaches for visualizing the medical informatics literature to show historical trends, associations, and aggregated summarized information to illustrate the state and changes in the IMIA Yearbook publications over the last quarter century.
Dual-task results and the lateralization of spatial orientation: artifact of test selection?
Bowers, C A; Milham, L M; Price, C
1998-01-01
An investigation was conducted to identify the degree to which results regarding the lateralization of spatial orientation among men and women are artifacts of test selection. A dual-task design was used to study possible lateralization differences, providing baseline and dual-task measures of spatial-orientation performance, right- and left-hand tapping, and vocalization of "cat, dog, horse." The Guilford-Zimmerman Test (Guilford & Zimmerman, 1953), the Eliot-Price Test (Eliot & Price, 1976), and the Stumpf-Fay Cube Perspectives Test (Stumpf & Fay, 1983) were the three spatial-orientation tests used to investigate possible artifacts of test selection. Twenty-eight right-handed male and 39 right-handed female undergraduates completed random baseline and dual-task sessions. Analyses indicated no significant sex-related differences in spatial-orientation ability for all three tests. Furthermore, there was no evidence of differential lateralization of spatial orientation between the sexes.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen Bo; State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Science, Beijing 100101; Xia Jing
Physiological and behavioral studies have demonstrated that a number of visual functions such as visual acuity, contrast sensitivity, and motion perception can be impaired by acute alcohol exposure. The orientation- and direction-selective responses of cells in primary visual cortex are thought to participate in the perception of form and motion. To investigate how orientation selectivity and direction selectivity of neurons are influenced by acute alcohol exposure in vivo, we used the extracellular single-unit recording technique to examine the response properties of neurons in primary visual cortex (A17) of adult cats. We found that alcohol reduces spontaneous activity, visual evoked unitmore » responses, the signal-to-noise ratio, and orientation selectivity of A17 cells. In addition, small but detectable changes in both the preferred orientation/direction and the bandwidth of the orientation tuning curve of strongly orientation-biased A17 cells were observed after acute alcohol administration. Our findings may provide physiological evidence for some alcohol-related deficits in visual function observed in behavioral studies.« less
Homography-based visual servo regulation of mobile robots.
Fang, Yongchun; Dixon, Warren E; Dawson, Darren M; Chawda, Prakash
2005-10-01
A monocular camera-based vision system attached to a mobile robot (i.e., the camera-in-hand configuration) is considered in this paper. By comparing corresponding target points of an object from two different camera images, geometric relationships are exploited to derive a transformation that relates the actual position and orientation of the mobile robot to a reference position and orientation. This transformation is used to synthesize a rotation and translation error system from the current position and orientation to the fixed reference position and orientation. Lyapunov-based techniques are used to construct an adaptive estimate to compensate for a constant, unmeasurable depth parameter, and to prove asymptotic regulation of the mobile robot. The contribution of this paper is that Lyapunov techniques are exploited to craft an adaptive controller that enables mobile robot position and orientation regulation despite the lack of an object model and the lack of depth information. Experimental results are provided to illustrate the performance of the controller.
Raval, Heli S; Nayak, J B; Patel, B M; Bhadesiya, C M
2015-06-01
The present study was undertaken to understand the zoonotic importance of canine scabies and dermatophytosis with special reference to the knowledge level of dog owners in urban areas of Gujarat. The study was carried out in randomly selected 120 dog owners of 3 urban cities (viz., Ahmedabad, Anand and Vadodara) of Gujarat state, India. Dog owners (i.e., respondents) were subjected to a detailed interview regarding the zoonotic importance of canine scabies and dermatophytosis in dogs. Ex-post-facto research design was selected because of the independent variables of the selected respondent population for the study. The crucial method used in collecting data was a field survey to generate null hypothesis (Ho1). Available data was subjected to statistical analysis. The three independent variables, viz., extension contact (r=0.522**), mass-media exposure (r=0.205*) and management orientation (r=0.264**) had significant relationship with knowledge of dog owners about zoonotic diseases. Other independent variables, viz., education, experience in dog keeping and housing space were observed to have negative and non-significant relationship with knowledge of dog owners about zoonotic diseases. Extension contact, exposure to extension mass-media, management orientation and innovation proneness among dog owners of 3 urban cities of Gujarat state had significant relationship with knowledge of dog owners on zoonotic aspects of canine scabies and dermatophytosis. Data provided new insights on the present status of zoonotic disease-awareness, which would be an aid to plan preventive measures.
Sadeh, Sadra; Rotter, Stefan
2014-01-01
Neurons in the primary visual cortex are more or less selective for the orientation of a light bar used for stimulation. A broad distribution of individual grades of orientation selectivity has in fact been reported in all species. A possible reason for emergence of broad distributions is the recurrent network within which the stimulus is being processed. Here we compute the distribution of orientation selectivity in randomly connected model networks that are equipped with different spatial patterns of connectivity. We show that, for a wide variety of connectivity patterns, a linear theory based on firing rates accurately approximates the outcome of direct numerical simulations of networks of spiking neurons. Distance dependent connectivity in networks with a more biologically realistic structure does not compromise our linear analysis, as long as the linearized dynamics, and hence the uniform asynchronous irregular activity state, remain stable. We conclude that linear mechanisms of stimulus processing are indeed responsible for the emergence of orientation selectivity and its distribution in recurrent networks with functionally heterogeneous synaptic connectivity. PMID:25469704
Eliminating barriers to transit-oriented development : final report, March 2010.
DOT National Transportation Integrated Search
2010-03-01
Transit-oriented development refers to dense, mixed-use development near transit facilities, : particularly denser housing development. Achieving such density is a politically difficult goal. In New : Jersey, the main barriers are community con...
NASA Astrophysics Data System (ADS)
Mouchi, Vincent; Vonlanthen, Pierre; Verrecchia, Eric P.; Crowley, Quentin G.
2016-04-01
Lophelia pertusa is a cold-water coral, which may form reefs by the association of multiple coralites within which a polyp lives. Each individual polyp builds an aragonite skeleton by an initial phase of early mineralization (traditionally referred to as centres of calcification) from which aragonite fibres grow in thickening deposits. The skeleton wall features successive optically opaque and translucent bands previously attributed to different regimes of growth as either uniform in crystal orientation (translucent bands) or with a chaotic organization (opaque bands). The processes involved in any organizational changes are still unknown. Microlayers in the coral wall, which represent separate periods of skeletal growth, have been recently identified and described. These growth patterns are readily visible under scanning electron microscope (SEM) after etching in dilute formic acid, but they do not necessarily form continuously visible structures. Here we present high quality SEM images and electron backscatter diffraction (EBSD) maps to study aragonite fibre orientation across the wall of L. pertusa. Both microlayers and opaque and translucent bands are compared to the crystallographic orientation of the aragonite fibres. EBSD maps and SEM images indicate that aragonite fibres do not exhibit a chaotic orientation, even in opaque bands. The absence of continuity of microlayers is partially explained by an association of multiple crystallographic preferred orientations of aragonite fibres. In the case of L. pertusa, careful textural characterisation is necessary prior to elemental or isotope analysis in order to select a skeletal transect representing a linear and continuous time period.
Jiang, Nan; Cortese, Daniel K; Lewis, M Jane; Ling, Pamela M
2016-06-01
Advertising influences people's health behaviors. Tobacco companies have linked tobacco and alcohol in their marketing activities. We examined how depictions of alcohol were placed in lifestyle magazines produced by tobacco companies, and if these references differed depending on if the magazine was oriented towards men, women, or if it was unisex. Content analysis of 6 different tobacco industry lifestyle magazines (73 issues), including 73 magazine covers, 1558 articles, 444 tobacco ads, and 695 non-tobacco ads. 14 of 73 (19%) magazine covers featured alcohol; 581 of 1558 (37%) magazine articles mentioned alcohol; 119 of 444 (27%) tobacco ads showed alcohol images; and 57 of 695 (8%) non-tobacco ads portrayed alcohol. Male-oriented magazines ( Unlimited , CML , and Real Edge ) contained the most alcohol references, and the references were mainly beer, mixed drinks, and liquor or spirits. Female-oriented magazines ( All Woman and Flair ) contained the fewest alcohol references, and wine and mixed drinks were the major types of alcoholic beverage portrayed. For unisex magazine ( P.S. ), the frequency of alcohol references fell between the male- and female-oriented magazines, and most frequently mentioned mixed drinks. Frequent depictions of smoking and drinking in tobacco industry lifestyle magazines might have reinforced norms about paired use of tobacco and alcohol among young adults. The pairing of tobacco and alcohol may particularly target young men. Anti-tobacco interventions need to address the co-use of tobacco and alcohol, change the social acceptability of smoking in any social settings, and tailor alcohol related anti-tobacco messaging by gender.
A study of parallelism of the occlusal plane and ala-tragus line.
Sadr, Katayoun; Sadr, Makan
2009-01-01
Orientation of the occlusal plane is one of the most important clinical procedures in prostho-dontic rehabilitation of edentulous patients. The aim of this study was to define the best posterior reference point of ala-tragus line for orientation of occlusal plane for complete denture fabrication. Fifty-three dental students (27 females and 26 males) with complete natural dentition and Angel's Class I occlusal relationship were selected. The subjects were photographed in natural head position while clenching on a Fox plane. After tracing the photographs, the angles between the following lines were measured: the occlusal plane (Fox plane) and the superior border of ala-tragus, the occlusal plane (Fox plane) and the middle of ala-tragus as well as the occlusal plane (Fox plane) and the inferior border of ala-tragus. Descriptive statistics, one sample t-test and independent t-test were used. P value less than 0.05 was considered significant. There was no parallelism between the occlusal plane and ala-tragus line with three different posterior ends and one sample t-test showed that the angles between them were significantly different from zero (p<0.05). However, the supe-rior border of ala-tragus line had the lowest mean angle, 1.80° (3.12) and was almost parallel to the occlusal plane. The superior border of the tragus is suggested as the posterior reference for ala-tragus line.
Masking reduces orientation selectivity in rat visual cortex
Alwis, Dasuni S.; Richards, Katrina L.
2016-01-01
In visual masking the perception of a target stimulus is impaired by a preceding (forward) or succeeding (backward) mask stimulus. The illusion is of interest because it allows uncoupling of the physical stimulus, its neuronal representation, and its perception. To understand the neuronal correlates of masking, we examined how masks affected the neuronal responses to oriented target stimuli in the primary visual cortex (V1) of anesthetized rats (n = 37). Target stimuli were circular gratings with 12 orientations; mask stimuli were plaids created as a binarized sum of all possible target orientations. Spatially, masks were presented either overlapping or surrounding the target. Temporally, targets and masks were presented for 33 ms, but the stimulus onset asynchrony (SOA) of their relative appearance was varied. For the first time, we examine how spatially overlapping and center-surround masking affect orientation discriminability (rather than visibility) in V1. Regardless of the spatial or temporal arrangement of stimuli, the greatest reductions in firing rate and orientation selectivity occurred for the shortest SOAs. Interestingly, analyses conducted separately for transient and sustained target response components showed that changes in orientation selectivity do not always coincide with changes in firing rate. Given the near-instantaneous reductions observed in orientation selectivity even when target and mask do not spatially overlap, we suggest that monotonic visual masking is explained by a combination of neural integration and lateral inhibition. PMID:27535373
Li, De-Jing; Gu, Zhi-Gang; Vohra, Ismail; Kang, Yao; Zhu, Yong-Sheng; Zhang, Jian
2017-05-01
This study reports an oriented and homogenous cobalt-metalloporphyrin network (PIZA-1) thin film prepared by liquid phase epitaxial (LPE) method. The thickness of the obtained thin films can be well controlled, and their photocurrent properties can also be tuned by LPE cycles or the introduction of conductive guest molecules (tetracyanoquinodimethane and C 60 ) into the PIZA-1 pores. The study of quartz crystal microbalance adsorption confirms that the PIZA-1 thin film with [110]-orientation presents much higher selectivity of benzene over toluene and p-xylene than that of the PIZA-1 powder with mixed orientations. These results reveal that the selective adsorption of volatile organic compounds highly depends on the growth orientations of porphyrin-based metal-organic framework thin films. Furthermore, the work will provide a new perspective for developing important semiconductive sensing materials with improved selectivity of guest compounds. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Krahe, Thomas E.; Wang, Weili; Medina, Alexandre E.
2009-01-01
Background Fetal alcohol spectrum disorders (FASD) are the leading cause of mental retardation in the western world and children with FASD present altered somatosensory, auditory and visual processing. There is growing evidence that some of these sensory processing problems may be related to altered cortical maps caused by impaired developmental neuronal plasticity. Methodology/Principal Findings Here we show that the primary visual cortex of ferrets exposed to alcohol during the third trimester equivalent of human gestation have decreased CREB phosphorylation and poor orientation selectivity revealed by western blotting, optical imaging of intrinsic signals and single-unit extracellular recording techniques. Treating animals several days after the period of alcohol exposure with a phosphodiesterase type 1 inhibitor (Vinpocetine) increased CREB phosphorylation and restored orientation selectivity columns and neuronal orientation tuning. Conclusions/Significance These findings suggest that CREB function is important for the maturation of orientation selectivity and that plasticity enhancement by vinpocetine may play a role in the treatment of sensory problems in FASD. PMID:19680548
Murphy-Baum, Benjamin L; Taylor, W Rowland
2015-09-30
Much of the computational power of the retina derives from the activity of amacrine cells, a large and diverse group of GABAergic and glycinergic inhibitory interneurons. Here, we identify an ON-type orientation-selective, wide-field, polyaxonal amacrine cell (PAC) in the rabbit retina and demonstrate how its orientation selectivity arises from the structure of the dendritic arbor and the pattern of excitatory and inhibitory inputs. Excitation from ON bipolar cells and inhibition arising from the OFF pathway converge to generate a quasi-linear integration of visual signals in the receptive field center. This serves to suppress responses to high spatial frequencies, thereby improving sensitivity to larger objects and enhancing orientation selectivity. Inhibition also regulates the magnitude and time course of excitatory inputs to this PAC through serial inhibitory connections onto the presynaptic terminals of ON bipolar cells. This presynaptic inhibition is driven by graded potentials within local microcircuits, similar in extent to the size of single bipolar cell receptive fields. Additional presynaptic inhibition is generated by spiking amacrine cells on a larger spatial scale covering several hundred microns. The orientation selectivity of this PAC may be a substrate for the inhibition that mediates orientation selectivity in some types of ganglion cells. Significance statement: The retina comprises numerous excitatory and inhibitory circuits that encode specific features in the visual scene, such as orientation, contrast, or motion. Here, we identify a wide-field inhibitory neuron that responds to visual stimuli of a particular orientation, a feature selectivity that is primarily due to the elongated shape of the dendritic arbor. Integration of convergent excitatory and inhibitory inputs from the ON and OFF visual pathways suppress responses to small objects and fine textures, thus enhancing selectivity for larger objects. Feedback inhibition regulates the strength and speed of excitation on both local and wide-field spatial scales. This study demonstrates how different synaptic inputs are regulated to tune a neuron to respond to specific features in the visual scene. Copyright © 2015 the authors 0270-6474/15/3513336-15$15.00/0.
Interactive effects of culture and sex hormones on the sex role self-concept
Pletzer, Belinda; Petasis, Ourania; Ortner, Tuulia M.; Cahill, Larry
2015-01-01
Sex role orientation, i.e., a person's masculinity or femininity, influences cognitive and emotional performance, like biological sex. While it is now widely accepted that sex differences are modulated by the hormonal status of female participants (menstrual cycle, hormonal contraceptive use), the question, whether hormonal status and sex hormones also modulate participants sex role orientation has hardly been addressed previously. The present study assessed sex role orientation and hormonal status as well as sex hormone levels in three samples of participants from two different cultures (Northern American, Middle European). Menstrual cycle phase did not affect participant's masculinity or femininity, but had a significant impact on reference group. While women in their follicular phase (low levels of female sex hormones) determined their masculinity and femininity in reference to men, women in their luteal phase (high levels of female sex hormones) determined their masculinity and femininity in reference to women. Hormonal contraceptive users rated themselves as significantly more feminine and less masculine than naturally cycling women. Furthermore, the impact of biological sex on the factorial structure of sex role orientation as well as the relationship of estrogen to masculinity/femininity was modulated by culture. We conclude that culture and sex hormones interactively affect sex role orientation and hormonal status of participants should be controlled for when assessing masculinity and/or femininity. PMID:26236181
Connection Between the ICRF and the Dynamical Reference Frame for the Outer Planets
NASA Astrophysics Data System (ADS)
da Silva Neto, D. N.; Assafin, M.; Andrei, A. H.; Vieira Martins, R.
2005-01-01
This work brings an approach intending to improve the connection between the Dynamical Reference Frame and the Extragalactic Reference Frame. For that, close encounters of outer Solar System objects and quasars are used. With this goal, Uranus, Neptune and two quasars were observed at Laborat´orio Nacional de Astrof´ısica (LNA), Brazil. The optical reference frame is the HCRF, as given by the UCAC2 catalogue. The first results show an accuracy of 45 mas - 50 mas in the optical positions. The optical minus radio offsets give the local orientation between the catalogue and radio frame. From this, it is possible to place the optical planet coordinates on the extragalactic frame. A comparison between the new corrected optical coordinates and the respective DE ephemeris to these planets can give the instant orientations of the Dynamical Reference Frame with regard to the ICRS, for this zone of outer Solar System.
Snijders, Thom E; Willemsen, Koen; van Gaalen, Steven M; Castelein, Rene M; Weinans, Harrie; de Gast, Arthur
2018-05-01
Dislocation is one of the main reasons for revision of total hip arthroplasty but dislocation rates have not changed in the past decades, compromising patients' well-being. Acetabular cup orientation plays a key role in implant stability and has been widely studied. This article investigates whether there is a consensus on optimal cup orientation, which is necessary when using a navigation system. A systematic search of the literature in the PubMed, Embase and Cochrane databases was performed (March 2017) to identify articles that investigated the direct relationship between cup orientation and dislocation, including a thorough evaluation of postoperative cup orientation assessment methods. Twenty eight relevant articles evaluating a direct relation between dislocation and cup orientation could not come to a consensus. The key reason is a lack of uniformity in the assessment of cup orientation. Cup orientation is assessed with different imaging modalities, different methodologies, different definitions for inclination and anteversion, several reference planes and distinct patient positions. All available studies lack uniformity in cup orientation assessment; therefore it is impossible to reach consensus on optimal cup orientation. Using navigation systems for placement of the cup is inevitably flawed when using different definitions in the preoperative planning, peroperative placement and postoperative evaluation. Further methodological development is required to assess cup orientation. Consequently, the postoperative assessment should be uniform, thus differentiating between anterior and posterior dislocation, use the same definitions for inclination and anteversion with the same reference plane and with the patient in the same position.
Sexual orientation and spatial memory.
Cánovas, Ma Rosa; Cimadevilla, José Manuel
2011-11-01
The present study aimed at determining the influence of sexual orientation in human spatial learning and memory. Participants performed the Boxes Room, a virtual reality version of the Holeboard. In Experiment I, a reference memory task, the position of the hidden rewards remained constant during the whole experiment. In Experiment II, a working memory task, the position of rewards changed between blocks. Each block consisted of two trials: One trial for acquisition and another for retrieval. The results of Experiment I showed that heterosexual men performed better than homosexual men and heterosexual women. They found the rewarded boxes faster. Moreover, homosexual participants committed more errors than heterosexuals. Experiment II showed that working memory abilities are the same in groups of different sexual orientation. These results suggest that sexual orientation is related to spatial navigation abilities, but mostly in men, and limited to reference memory, which depends more on the function of the hippocampal system.
Heyers, Dominik; Manns, Martina; Luksch, Harald; Güntürkün, Onur; Mouritsen, Henrik
2007-09-26
The magnetic compass of migratory birds has been suggested to be light-dependent. Retinal cryptochrome-expressing neurons and a forebrain region, "Cluster N", show high neuronal activity when night-migratory songbirds perform magnetic compass orientation. By combining neuronal tracing with behavioral experiments leading to sensory-driven gene expression of the neuronal activity marker ZENK during magnetic compass orientation, we demonstrate a functional neuronal connection between the retinal neurons and Cluster N via the visual thalamus. Thus, the two areas of the central nervous system being most active during magnetic compass orientation are part of an ascending visual processing stream, the thalamofugal pathway. Furthermore, Cluster N seems to be a specialized part of the visual wulst. These findings strongly support the hypothesis that migratory birds use their visual system to perceive the reference compass direction of the geomagnetic field and that migratory birds "see" the reference compass direction provided by the geomagnetic field.
Foster, D H; Westland, S
1998-01-01
Visual search for an edge or line element differing in orientation from a background of other edge or line elements can be performed rapidly and effortlessly. In this study, based on psychophysical measurements with ten human observers, threshold values of the angle between a target and background line elements were obtained as functions of background-element orientation, in brief masked displays. A repeated-loess analysis of the threshold functions suggested the existence of several groups of orientation-selective mechanisms contributing to rapid orientated-line detection; specifically, coarse, intermediate and fine mechanisms with preferred orientations spaced at angles of approximately 90 degrees, 35 degrees, and 10 degrees-25 degrees, respectively. The preferred orientations of coarse and some intermediate mechanisms coincided with the vertical or horizontal of the frontoparallel plane, but the preferred orientations of fine mechanisms varied randomly from observer to observer, possibly reflecting individual variations in neuronal sampling characteristics. PMID:9753784
Spatial attention can modulate unconscious orientation processing.
Bahrami, Bahador; Carmel, David; Walsh, Vincent; Rees, Geraint; Lavie, Nilli
2008-01-01
It has recently been suggested that visual spatial attention can only affect consciously perceived events. We measured the effects of sustained spatial attention on orientation-selective adaptation to gratings, rendered invisible by prolonged interocular suppression. Spatial attention augmented the orientation-selective adaptation to invisible adaptor orientation. The effect of attention was clearest for test stimuli at peri-threshold, intermediate contrast levels, suggesting that previous negative results were due to assessing orientation discrimination at maximum contrast. On the basis of these findings we propose a constrained hypothesis for the difference between neuronal mechanisms of spatial attention in the presence versus absence of awareness.
Attention improves encoding of task-relevant features in the human visual cortex
Jehee, Janneke F.M.; Brady, Devin K.; Tong, Frank
2011-01-01
When spatial attention is directed towards a particular stimulus, increased activity is commonly observed in corresponding locations of the visual cortex. Does this attentional increase in activity indicate improved processing of all features contained within the attended stimulus, or might spatial attention selectively enhance the features relevant to the observer’s task? We used fMRI decoding methods to measure the strength of orientation-selective activity patterns in the human visual cortex while subjects performed either an orientation or contrast discrimination task, involving one of two laterally presented gratings. Greater overall BOLD activation with spatial attention was observed in areas V1-V4 for both tasks. However, multivariate pattern analysis revealed that orientation-selective responses were enhanced by attention only when orientation was the task-relevant feature, and not when the grating’s contrast had to be attended. In a second experiment, observers discriminated the orientation or color of a specific lateral grating. Here, orientation-selective responses were enhanced in both tasks but color-selective responses were enhanced only when color was task-relevant. In both experiments, task-specific enhancement of feature-selective activity was not confined to the attended stimulus location, but instead spread to other locations in the visual field, suggesting the concurrent involvement of a global feature-based attentional mechanism. These results suggest that attention can be remarkably selective in its ability to enhance particular task-relevant features, and further reveal that increases in overall BOLD amplitude are not necessarily accompanied by improved processing of stimulus information. PMID:21632942
Attention improves encoding of task-relevant features in the human visual cortex.
Jehee, Janneke F M; Brady, Devin K; Tong, Frank
2011-06-01
When spatial attention is directed toward a particular stimulus, increased activity is commonly observed in corresponding locations of the visual cortex. Does this attentional increase in activity indicate improved processing of all features contained within the attended stimulus, or might spatial attention selectively enhance the features relevant to the observer's task? We used fMRI decoding methods to measure the strength of orientation-selective activity patterns in the human visual cortex while subjects performed either an orientation or contrast discrimination task, involving one of two laterally presented gratings. Greater overall BOLD activation with spatial attention was observed in visual cortical areas V1-V4 for both tasks. However, multivariate pattern analysis revealed that orientation-selective responses were enhanced by attention only when orientation was the task-relevant feature and not when the contrast of the grating had to be attended. In a second experiment, observers discriminated the orientation or color of a specific lateral grating. Here, orientation-selective responses were enhanced in both tasks, but color-selective responses were enhanced only when color was task relevant. In both experiments, task-specific enhancement of feature-selective activity was not confined to the attended stimulus location but instead spread to other locations in the visual field, suggesting the concurrent involvement of a global feature-based attentional mechanism. These results suggest that attention can be remarkably selective in its ability to enhance particular task-relevant features and further reveal that increases in overall BOLD amplitude are not necessarily accompanied by improved processing of stimulus information.
Interactions of form and orientation
NASA Technical Reports Server (NTRS)
Mittelstaedt, Horst
1989-01-01
It is well known that the orientation of an optical pattern relative to egocentric or extraneous references affects its figural quality, that is, alters its perceived form and concomitantly delays or quickens its identification (Rock 1973). A square presented in the frontal plane to an upright person (S), for instance, changes from a box to a diamond when it is rotated with respect to the S's median plane by 45 deg. This angle, that is, the angle between the orientations of the pattern in which the two apparent figures (Gestalten) attain a summit of purity and distinctness, will be called the figural disparity of the pattern. If, as in this case, the S is upright, the retinal meridian and the subjective vertical (SV) are both in the viewer's median plane. The question arises with respect to which of these orientation references the two figures are identified. The answer may be found when the pattern and the S are oriented in such a way that the projections of the retinal meridian and the SV into the plane of the pattern diverge by the pattern's figural disparity or its periodic multiples: that is, in this case of a square by 45 or 135 deg, respectively. Similarly, which reference determines whether an equilateral triangle is seen as a pyramid or a traffic warning sign may be revealed at a divergence of SV and retinal meridian of 60 or 180 deg, respectively. It is generally found that for head roll tilts (Rho) and figural disparities of up to 90 deg, the figure whose axis coincides with the SV is seen. At head tilts of Rho=180 deg, however, the retinal reference dominates, as a rule independently of the figural disparity.
New Kids on the Block: How To Recruit, Select, and Orient School Employees.
ERIC Educational Resources Information Center
Anderson, Mark E.; And Others
A conference presentation on the recruitment, selection, and orientation of school employees are highlighted in this paper. Part 1 describes organizing strategies for recruitment and selection, such as defining administrative roles, assessing current practices, and scheduling. Practices for attracting capable teacher candidates are presented in…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Johnson, D.G.; Niemczyk, M.P.; Minsek, D.W.
1993-06-30
The photochemistry of four chlorophyll-porphyrin-naphthoquinone molecules possessing both fixed distances and orientations between the three components is described. These molecules consist of a methyl pyropheophorbide a or pyrochlorophyllide a that is directly bonded at its 3-position to the 5-position of a 2,8,12,18-tetraethyl-3,7,13,-17-tetramethylporphyrin, which is in turn bonded at its 15-position to a 2-triptycenenaphthoquinone. In addition, porphyrin-quinone compounds in which the chlorins are replaced by a p-tolyl group were also prepared as reference compounds. Selective metalation of the macrocycles with zinc gives the series ZCHPNQ, ZCZPNQ, HCZPNQ, HCHPNQ, HPNQ, and ZPNQ, where H, Z, C, P, and NQ denote free base,more » Zn derivative, chlorophyll, porphyrin, and naphthoquinone, respectively. Selective excitation of ZC in ZCZPNQ and ZCHPNQ, and HC in HCHPNQ dissolved in butyronitrile yields ZC[sup +]ZPNQ[sup [minus
Viste, A; Chouteau, J; Testa, R; Chèze, L; Fessy, M-H; Moyen, B
2011-05-01
Accurate positioning of the acetabular cup in primary total hip arthroplasty is critical to decrease the rate of dislocation. Inaccurate orientation of the cup is the most common error during this procedure. Target acetabular orientation is still controversial. An original study found a dislocation rate of 0.6% when the cup was aligned with the transverse acetabular ligament (TAL). TAL is a patient-specific anatomical landmark and a tool for cup orientation. Eight cadaveric pelves (14 hips included for study) were harvested in toto at our research laboratory. Anatomical versions of the TAL, labrum and horns were measured in relation to the anterior pelvic plane. A navigator sensor and an optoelectronic device (Motion Analysis™) were used. Anatomical versions of the TAL, horns and labrum averaged 1.9° (range, -8° to +13.3°), 3° (range, -12.2° to 14°), and 26.3° (range, 17.4° to 41.8°), respectively. To our knowledge, this is the first study to report the orientation of the periacetabular soft-tissues. TAL anteversion was outside the safe zone described by Lewinnek, while labrum anteversion was within this safe-zone. We discuss the reference used, Lewinnek's safe zone, and functional orientation of the implants. Lewinnek's safe-zone does not seem to be valid. The TAL seems to be a specific reference for each patient but its reliability must still be confirmed as an adequate reference for positioning the cup in total hip arthroplasty. Copyright © 2011 Elsevier Masson SAS. All rights reserved.
Deconstructing sexual orientation: understanding the phenomena of sexual orientation.
Stein, T S
1997-01-01
The very terms of a debate about whether or not sexual orientation is primarily a biological phenomenon fail to consider the complex origins of the phenomenon. Deconstruction of the term "homosexuality" shows that it refers to multiple factors which cannot be studied as or subsumed under a unitary concept. Adequate understanding of sexual orientation must consider the developmental, interpersonal, experiential, and cultural dimensions of sexuality, as well as any biological contributions to sexual attraction, behavior, and identity.
The impact of orientation filtering on face-selective neurons in monkey inferior temporal cortex.
Taubert, Jessica; Goffaux, Valerie; Van Belle, Goedele; Vanduffel, Wim; Vogels, Rufin
2016-02-16
Faces convey complex social signals to primates. These signals are tolerant of some image transformations (e.g. changes in size) but not others (e.g. picture-plane rotation). By filtering face stimuli for orientation content, studies of human behavior and brain responses have shown that face processing is tuned to selective orientation ranges. In the present study, for the first time, we recorded the responses of face-selective neurons in monkey inferior temporal (IT) cortex to intact and scrambled faces that were filtered to selectively preserve horizontal or vertical information. Guided by functional maps, we recorded neurons in the lateral middle patch (ML), the lateral anterior patch (AL), and an additional region located outside of the functionally defined face-patches (CONTROL). We found that neurons in ML preferred horizontal-passed faces over their vertical-passed counterparts. Neurons in AL, however, had a preference for vertical-passed faces, while neurons in CONTROL had no systematic preference. Importantly, orientation filtering did not modulate the firing rate of neurons to phase-scrambled face stimuli in any recording region. Together these results suggest that face-selective neurons found in the face-selective patches are differentially tuned to orientation content, with horizontal tuning in area ML and vertical tuning in area AL.
Introducing an Instrument to Assess Time Orientation and Time Relation in Adolescents
ERIC Educational Resources Information Center
Mello, Zena R.; Finan, Laura J.; Worrell, Frank C.
2013-01-01
We report on two studies that examine new instruments that assess time orientation and time relation in adolescents. These concepts refer to how individuals think about the past, the present, and the future, with time orientation defined as the emphasis one gives toward each time period and time relation defined as the degree one perceives that…
ERIC Educational Resources Information Center
Lavine, Carolyn
1992-01-01
Describes orienteering courses for children, including courses that introduce young children to the idea of navigating in the outdoors and courses that teach map and compass skills and problem-solving techniques to older children. Lists sources of information and references. (SV)
Tong, Frank; Harrison, Stephenie A; Dewey, John A; Kamitani, Yukiyasu
2012-11-15
Orientation-selective responses can be decoded from fMRI activity patterns in the human visual cortex, using multivariate pattern analysis (MVPA). To what extent do these feature-selective activity patterns depend on the strength and quality of the sensory input, and might the reliability of these activity patterns be predicted by the gross amplitude of the stimulus-driven BOLD response? Observers viewed oriented gratings that varied in luminance contrast (4, 20 or 100%) or spatial frequency (0.25, 1.0 or 4.0 cpd). As predicted, activity patterns in early visual areas led to better discrimination of orientations presented at high than low contrast, with greater effects of contrast found in area V1 than in V3. A second experiment revealed generally better decoding of orientations at low or moderate as compared to high spatial frequencies. Interestingly however, V1 exhibited a relative advantage at discriminating high spatial frequency orientations, consistent with the finer scale of representation in the primary visual cortex. In both experiments, the reliability of these orientation-selective activity patterns was well predicted by the average BOLD amplitude in each region of interest, as indicated by correlation analyses, as well as decoding applied to a simple model of voxel responses to simulated orientation columns. Moreover, individual differences in decoding accuracy could be predicted by the signal-to-noise ratio of an individual's BOLD response. Our results indicate that decoding accuracy can be well predicted by incorporating the amplitude of the BOLD response into simple simulation models of cortical selectivity; such models could prove useful in future applications of fMRI pattern classification. Copyright © 2012 Elsevier Inc. All rights reserved.
Tong, Frank; Harrison, Stephenie A.; Dewey, John A.; Kamitani, Yukiyasu
2012-01-01
Orientation-selective responses can be decoded from fMRI activity patterns in the human visual cortex, using multivariate pattern analysis (MVPA). To what extent do these feature-selective activity patterns depend on the strength and quality of the sensory input, and might the reliability of these activity patterns be predicted by the gross amplitude of the stimulus-driven BOLD response? Observers viewed oriented gratings that varied in luminance contrast (4, 20 or 100%) or spatial frequency (0.25, 1.0 or 4.0 cpd). As predicted, activity patterns in early visual areas led to better discrimination of orientations presented at high than low contrast, with greater effects of contrast found in area V1 than in V3. A second experiment revealed generally better decoding of orientations at low or moderate as compared to high spatial frequencies. Interestingly however, V1 exhibited a relative advantage at discriminating high spatial frequency orientations, consistent with the finer scale of representation in the primary visual cortex. In both experiments, the reliability of these orientation-selective activity patterns was well predicted by the average BOLD amplitude in each region of interest, as indicated by correlation analyses, as well as decoding applied to a simple model of voxel responses to simulated orientation columns. Moreover, individual differences in decoding accuracy could be predicted by the signal-to-noise ratio of an individual's BOLD response. Our results indicate that decoding accuracy can be well predicted by incorporating the amplitude of the BOLD response into simple simulation models of cortical selectivity; such models could prove useful in future applications of fMRI pattern classification. PMID:22917989
Sexual orientation data collection and progress toward Healthy People 2010.
Sell, R L; Becker, J B
2001-06-01
Without scientifically obtained data and published reports, it is difficult to raise awareness and acquire adequate resources to address the health concerns of lesbian, gay, and bisexual Americans. The Department of Health and Human Services must recognize gaps in its information systems regarding sexual orientation data and take immediate steps to monitor and eliminate health disparities as delineated in Healthy People 2010. A paper supported by funding from the Office of the Assistant Secretary for Planning and Evaluation explores these concerns and suggests that the department (1) create work groups to examine the collection of sexual orientation data; (2) create a set of guiding principles to govern the process of selecting standard definitions and measures; (3) recognize that racial/ethnic, immigrant-status, age, socioeconomic, and geographic differences must be taken into account when standard measures of sexual orientation are selected; (4) select a minimum set of standard sexual orientation measures; and (5) develop a long-range strategic plan for the collection of sexual orientation data.
Sexual orientation data collection and progress toward Healthy People 2010.
Sell, R L; Becker, J B
2001-01-01
Without scientifically obtained data and published reports, it is difficult to raise awareness and acquire adequate resources to address the health concerns of lesbian, gay, and bisexual Americans. The Department of Health and Human Services must recognize gaps in its information systems regarding sexual orientation data and take immediate steps to monitor and eliminate health disparities as delineated in Healthy People 2010. A paper supported by funding from the Office of the Assistant Secretary for Planning and Evaluation explores these concerns and suggests that the department (1) create work groups to examine the collection of sexual orientation data; (2) create a set of guiding principles to govern the process of selecting standard definitions and measures; (3) recognize that racial/ethnic, immigrant-status, age, socioeconomic, and geographic differences must be taken into account when standard measures of sexual orientation are selected; (4) select a minimum set of standard sexual orientation measures; and (5) develop a long-range strategic plan for the collection of sexual orientation data. PMID:11392926
Isableu, B; Ohlmann, T; Cremieux, J; Vuillerme, N; Amblard, B; Gresty, M A
2010-09-01
The causes of the interindividual differences (IDs) in how we perceive and control spatial orientation are poorly understood. Here, we propose that IDs partly reflect preferred modes of spatial referencing and that these preferences or "styles" are maintained from the level of spatial perception to that of motor control. Two groups of experimental subjects, one with high visual field dependency (FD) and one with marked visual field independency (FI) were identified by the Rod and Frame Test, which identifies relative dependency on a visual frame of reference (VFoR). FD and FI subjects were tasked with standing still in conditions of increasing postural difficulty while visual cues of self-orientation (a visual frame tilted in roll) and self-motion (in stroboscopic illumination) were varied and in darkness to assess visual dependency. Postural stability, overall body orientation and modes of segmental stabilization relative to either external (space) or egocentric (adjacent segments) frames of reference in the roll plane were analysed. We hypothesized that a moderate challenge to balance should enhance subjects' reliance on VFoR, particularly in FD subjects, whereas a substantial challenge should constrain subjects to use a somatic-vestibular based FoR to prevent falling in which case IDs would vanish. The results showed that with increasing difficulty, FD subjects became more unstable and more disoriented shown by larger effects of the tilted visual frame on posture. Furthermore, their preference to coalign body/VFoR coordinate systems lead to greater fixation of the head-trunk articulation and stabilization of the hip in space, whereas the head and trunk remained more stabilized in space with the hip fixed on the leg in FI subjects. These results show that FD subjects have difficulties at identifying and/or adopting a more appropriate FoR based on proprioceptive and vestibular cues to regulate the coalignment of posturo/exocentric FoRs. The FI subjects' resistance in the face of altered VFoR and balance challenge resides in their greater ability to coordinate movement by coaligning body axes with more appropriate FoRs (provided by proprioceptive and vestibular co-variance). Copyright (c) 2010 IBRO. Published by Elsevier Ltd. All rights reserved.
Surface immobilized antibody orientation determined using ToF-SIMS and multivariate analysis.
Welch, Nicholas G; Madiona, Robert M T; Payten, Thomas B; Easton, Christopher D; Pontes-Braz, Luisa; Brack, Narelle; Scoble, Judith A; Muir, Benjamin W; Pigram, Paul J
2017-06-01
Antibody orientation at solid phase interfaces plays a critical role in the sensitive detection of biomolecules during immunoassays. Correctly oriented antibodies with solution-facing antigen binding regions have improved antigen capture as compared to their randomly oriented counterparts. Direct characterization of oriented proteins with surface analysis methods still remains a challenge however surface sensitive techniques such as Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) provide information-rich data that can be used to probe antibody orientation. Diethylene glycol dimethyl ether plasma polymers (DGpp) functionalized with chromium (DGpp+Cr) have improved immunoassay performance that is indicative of preferential antibody orientation. Herein, ToF-SIMS data from proteolytic fragments of anti-EGFR antibody bound to DGpp and DGpp+Cr are used to construct artificial neural network (ANN) and principal component analysis (PCA) models indicative of correctly oriented systems. Whole antibody samples (IgG) test against each of the models indicated preferential antibody orientation on DGpp+Cr. Cross-reference between ANN and PCA models yield 20 mass fragments associated with F(ab') 2 region representing correct orientation, and 23 mass fragments associated with the Fc region representing incorrect orientation. Mass fragments were then compared to amino acid fragments and amino acid composition in F(ab') 2 and Fc regions. A ratio of the sum of the ToF-SIMS ion intensities from the F(ab') 2 fragments to the Fc fragments demonstrated a 50% increase in intensity for IgG on DGpp+Cr as compared to DGpp. The systematic data analysis methodology employed herein offers a new approach for the investigation of antibody orientation applicable to a range of substrates. Controlled orientation of antibodies at solid phases is critical for maximizing antigen detection in biosensors and immunoassays. Surface-sensitive techniques (such as ToF-SIMS), capable of direct characterization of surface immobilized and oriented antibodies, are under-utilized in current practice. Selection of a small number of mass fragments for analysis, typically pertaining to amino acids, is commonplace in literature, leaving the majority of the information-rich spectra unanalyzed. The novelty of this work is the utilization of a comprehensive, unbiased mass fragment list and the employment of principal component analysis (PCA) and artificial neural network (ANN) models in a unique methodology to prove antibody orientation. This methodology is of significant and broad interest to the scientific community as it is applicable to a range of substrates and allows for direct, label-free characterization of surface bound proteins. Copyright © 2017 Acta Materialia Inc. All rights reserved.
A morphological basis for orientation tuning in primary visual cortex.
Mooser, François; Bosking, William H; Fitzpatrick, David
2004-08-01
Feedforward connections are thought to be important in the generation of orientation-selective responses in visual cortex by establishing a bias in the sampling of information from regions of visual space that lie along a neuron's axis of preferred orientation. It remains unclear, however, which structural elements-dendrites or axons-are ultimately responsible for conveying this sampling bias. To explore this question, we have examined the spatial arrangement of feedforward axonal connections that link non-oriented neurons in layer 4 and orientation-selective neurons in layer 2/3 of visual cortex in the tree shrew. Target sites of labeled boutons in layer 2/3 resulting from focal injections of biocytin in layer 4 show an orientation-specific axial bias that is sufficient to confer orientation tuning to layer 2/3 neurons. We conclude that the anisotropic arrangement of axon terminals is the principal source of the orientation bias contributed by feedforward connections.
An evaluation of the effects of transit oriented development in a suburban environment
DOT National Transportation Integrated Search
2010-10-01
Transit-Oriented Development (TOD) refers to dense, pedestrian-friendly, livable communities : that have good transit as a nucleus. While transit facilities are missing in most suburban towns and the residents are heavily dependent on their vehicles,...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Burgmans, Mark Christiaan, E-mail: m.c.burgmans@lumc.nl; Harder, J. Michiel den, E-mail: chiel.den.harder@gmail.com; Meershoek, Philippa, E-mail: P.Meershoek@lumc.nl
PurposeTo determine the accuracy of automatic and manual co-registration methods for image fusion of three-dimensional computed tomography (CT) with real-time ultrasonography (US) for image-guided liver interventions.Materials and MethodsCT images of a skills phantom with liver lesions were acquired and co-registered to US using GE Logiq E9 navigation software. Manual co-registration was compared to automatic and semiautomatic co-registration using an active tracker. Also, manual point registration was compared to plane registration with and without an additional translation point. Finally, comparison was made between manual and automatic selection of reference points. In each experiment, accuracy of the co-registration method was determined bymore » measurement of the residual displacement in phantom lesions by two independent observers.ResultsMean displacements for a superficial and deep liver lesion were comparable after manual and semiautomatic co-registration: 2.4 and 2.0 mm versus 2.0 and 2.5 mm, respectively. Both methods were significantly better than automatic co-registration: 5.9 and 5.2 mm residual displacement (p < 0.001; p < 0.01). The accuracy of manual point registration was higher than that of plane registration, the latter being heavily dependent on accurate matching of axial CT and US images by the operator. Automatic reference point selection resulted in significantly lower registration accuracy compared to manual point selection despite lower root-mean-square deviation (RMSD) values.ConclusionThe accuracy of manual and semiautomatic co-registration is better than that of automatic co-registration. For manual co-registration using a plane, choosing the correct plane orientation is an essential first step in the registration process. Automatic reference point selection based on RMSD values is error-prone.« less
A spatial reference frame model of Beijing based on spatial cognitive experiment
NASA Astrophysics Data System (ADS)
Zhang, Jie; Zhang, Jing; Liu, Yu
2006-10-01
Orientation relation in the spatial relation is very important in GIS. People can obtain orientation information by making use of map reading and the cognition of the surrounding environment, and then create the spatial reference frame. City is a kind of special spatial environment, a person with life experiences has some spatial knowledge about the city where he or she lives in. Based on the spatial knowledge of the city environment, people can position, navigate and understand the meaning embodied in the environment correctly. Beijing as a real geographic space, its layout is very special and can form a kind of new spatial reference frame. Based on the characteristics of the layout of Beijing city, this paper will introduce a new spatial reference frame of Beijing and use two psychological experiments to validate its cognitive plausibility.
Impact of seasonal and postglacial surface displacement on global reference frames
NASA Astrophysics Data System (ADS)
Krásná, Hana; Böhm, Johannes; King, Matt; Memin, Anthony; Shabala, Stanislav; Watson, Christopher
2014-05-01
The calculation of actual station positions requires several corrections which are partly recommended by the International Earth Rotation and Reference Systems Service (IERS) Conventions (e.g., solid Earth tides and ocean tidal loading) as well as other corrections, e.g. accounting for hydrology and atmospheric loading. To investigate the pattern of omitted non-linear seasonal motion we estimated empirical harmonic models for selected stations within a global solution of suitable Very Long Baseline Interferometry (VLBI) sessions as well as mean annual models by stacking yearly time series of station positions. To validate these models we compare them to displacement series obtained from the Gravity Recovery and Climate Experiment (GRACE) data and to hydrology corrections determined from global models. Furthermore, we assess the impact of the seasonal station motions on the celestial reference frame as well as on Earth orientation parameters derived from real and also artificial VLBI observations. In the second part of the presentation we apply vertical rates of the ICE-5G_VM2_2012 vertical land movement grid on vertical station velocities. We assess the impact of postglacial uplift on the variability in the scale given different sampling of the postglacial signal in time and hence on the uncertainty in the scale rate of the estimated terrestrial reference frame.
Junk, Matthias J.N.; Spiess, Hans W.; Hinderberger, Dariush
2011-01-01
The structure of human serum albumin loaded with a metal porphyrin and fatty acids in solution is characterized by orientation-selective double electron-electron resonance (DEER) spectroscopy. Human serum albumin, spin-labeled fatty acids, and Cu(II) protoporphyrin IX—a hemin analog—form a fully self-assembled system that allows obtaining distances and mutual orientations between the paramagnetic guest molecules. We report a simplified analysis for the orientation-selective DEER data which can be applied when the orientation selection of one spin in the spin pair dominates the orientation selection of the other spin. The dipolar spectra reveal a dominant distance of 3.85 nm and a dominant orientation of the spin-spin vectors between Cu(II) protoporphyrin IX and 16-doxyl stearic acid, the electron paramagnetic resonance reporter group of the latter being located near the entry points to the fatty acid binding sites. This observation is in contrast to crystallographic data that suggest an asymmetric distribution of the entry points in the protein and hence the occurrence of various distances. In conjunction with the findings of a recent DEER study, the obtained data are indicative of a symmetric distribution of the binding site entries on the protein's surface. The overall anisotropic shape of the protein is reflected by one spin-spin vector orientation dominating the DEER data. PMID:21539799
A privacy-preserving solution for compressed storage and selective retrieval of genomic data.
Huang, Zhicong; Ayday, Erman; Lin, Huang; Aiyar, Raeka S; Molyneaux, Adam; Xu, Zhenyu; Fellay, Jacques; Steinmetz, Lars M; Hubaux, Jean-Pierre
2016-12-01
In clinical genomics, the continuous evolution of bioinformatic algorithms and sequencing platforms makes it beneficial to store patients' complete aligned genomic data in addition to variant calls relative to a reference sequence. Due to the large size of human genome sequence data files (varying from 30 GB to 200 GB depending on coverage), two major challenges facing genomics laboratories are the costs of storage and the efficiency of the initial data processing. In addition, privacy of genomic data is becoming an increasingly serious concern, yet no standard data storage solutions exist that enable compression, encryption, and selective retrieval. Here we present a privacy-preserving solution named SECRAM (Selective retrieval on Encrypted and Compressed Reference-oriented Alignment Map) for the secure storage of compressed aligned genomic data. Our solution enables selective retrieval of encrypted data and improves the efficiency of downstream analysis (e.g., variant calling). Compared with BAM, the de facto standard for storing aligned genomic data, SECRAM uses 18% less storage. Compared with CRAM, one of the most compressed nonencrypted formats (using 34% less storage than BAM), SECRAM maintains efficient compression and downstream data processing, while allowing for unprecedented levels of security in genomic data storage. Compared with previous work, the distinguishing features of SECRAM are that (1) it is position-based instead of read-based, and (2) it allows random querying of a subregion from a BAM-like file in an encrypted form. Our method thus offers a space-saving, privacy-preserving, and effective solution for the storage of clinical genomic data. © 2016 Huang et al.; Published by Cold Spring Harbor Laboratory Press.
A privacy-preserving solution for compressed storage and selective retrieval of genomic data
Huang, Zhicong; Ayday, Erman; Lin, Huang; Aiyar, Raeka S.; Molyneaux, Adam; Xu, Zhenyu; Hubaux, Jean-Pierre
2016-01-01
In clinical genomics, the continuous evolution of bioinformatic algorithms and sequencing platforms makes it beneficial to store patients’ complete aligned genomic data in addition to variant calls relative to a reference sequence. Due to the large size of human genome sequence data files (varying from 30 GB to 200 GB depending on coverage), two major challenges facing genomics laboratories are the costs of storage and the efficiency of the initial data processing. In addition, privacy of genomic data is becoming an increasingly serious concern, yet no standard data storage solutions exist that enable compression, encryption, and selective retrieval. Here we present a privacy-preserving solution named SECRAM (Selective retrieval on Encrypted and Compressed Reference-oriented Alignment Map) for the secure storage of compressed aligned genomic data. Our solution enables selective retrieval of encrypted data and improves the efficiency of downstream analysis (e.g., variant calling). Compared with BAM, the de facto standard for storing aligned genomic data, SECRAM uses 18% less storage. Compared with CRAM, one of the most compressed nonencrypted formats (using 34% less storage than BAM), SECRAM maintains efficient compression and downstream data processing, while allowing for unprecedented levels of security in genomic data storage. Compared with previous work, the distinguishing features of SECRAM are that (1) it is position-based instead of read-based, and (2) it allows random querying of a subregion from a BAM-like file in an encrypted form. Our method thus offers a space-saving, privacy-preserving, and effective solution for the storage of clinical genomic data. PMID:27789525
Orientation selectivity sharpens motion detection in Drosophila
Fisher, Yvette E.; Silies, Marion; Clandinin, Thomas R.
2015-01-01
SUMMARY Detecting the orientation and movement of edges in a scene is critical to visually guided behaviors of many animals. What are the circuit algorithms that allow the brain to extract such behaviorally vital visual cues? Using in vivo two-photon calcium imaging in Drosophila, we describe direction selective signals in the dendrites of T4 and T5 neurons, detectors of local motion. We demonstrate that this circuit performs selective amplification of local light inputs, an observation that constrains motion detection models and confirms a core prediction of the Hassenstein-Reichardt Correlator (HRC). These neurons are also orientation selective, responding strongly to static features that are orthogonal to their preferred axis of motion, a tuning property not predicted by the HRC. This coincident extraction of orientation and direction sharpens directional tuning through surround inhibition and reveals a striking parallel between visual processing in flies and vertebrate cortex, suggesting a universal strategy for motion processing. PMID:26456048
Refinement of ground reference data with segmented image data
NASA Technical Reports Server (NTRS)
Robinson, Jon W.; Tilton, James C.
1991-01-01
One of the ways to determine ground reference data (GRD) for satellite remote sensing data is to photo-interpret low altitude aerial photographs and then digitize the cover types on a digitized tablet and register them to 7.5 minute U.S.G.S. maps (that were themselves digitized). The resulting GRD can be registered to the satellite image or, vice versa. Unfortunately, there are many opportunities for error when using digitizing tablet and the resolution of the edges for the GRD depends on the spacing of the points selected on the digitizing tablet. One of the consequences of this is that when overlaid on the image, errors and missed detail in the GRD become evident. An approach is discussed for correcting these errors and adding detail to the GRD through the use of a highly interactive, visually oriented process. This process involves the use of overlaid visual displays of the satellite image data, the GRD, and a segmentation of the satellite image data. Several prototype programs were implemented which provide means of taking a segmented image and using the edges from the reference data to mask out these segment edges that are beyond a certain distance from the reference data edges. Then using the reference data edges as a guide, those segment edges that remain and that are judged not to be image versions of the reference edges are manually marked and removed. The prototype programs that were developed and the algorithmic refinements that facilitate execution of this task are described.
Why the Greenwich Meridian Moved
2015-08-01
that are related to the geocentric reference frame introduced by the Bureau International de l’Heure (BIH) in 1984. This BIHTerrestrial System provided...the basis for orientation of subsequent geocentric reference frames, including all realizations of theWorld Geodetic Sys- tem 1984 and the...astronomical time. The coordinates of satellite-navigation receivers are provided in reference frames that are related to the geocentric reference
Conservative Orientation as a Determinant of Hopelessness.
ERIC Educational Resources Information Center
Cheung, Chau-Kiu; Kwok, Siu-Tong
1996-01-01
Hypothesizes that a conservative and individualistic orientation results in the fatalistic, alienated, and helpless outlook known as hopelessness. Provides extensive references to studies and theories characterizing conservatism and a work ethic belief as manifestations of an a maladaptive stage of psychological development. (MJP)
van Doorn, Andrea J.; Wagemans, Johan
2016-01-01
Research on the influence of reference frames has generally focused on visual phenomena such as the oblique effect, the subjective visual vertical, the perceptual upright, and ambiguous figures. Another line of research concerns mental rotation studies in which participants had to discriminate between familiar or previously seen 2-D figures or pictures of 3-D objects and their rotated versions. In the present study, we disentangled the influence of the environmental and the viewer-centered reference frame, as classically done, by comparing the performances obtained in various picture and participant orientations. However, this time, the performance is the pictorial relief: the probed 3-D shape percept of the depicted object reconstructed from the local attitude settings of the participant. Comparisons between the pictorial reliefs based on different picture and participant orientations led to two major findings. First, in general, the pictorial reliefs were highly similar if the orientation of the depicted object was vertical with regard to the environmental or the viewer-centered reference frame. Second, a viewpoint-from-above interpretation could almost completely account for the shears occurring between the pictorial reliefs. More specifically, the shears could largely be considered as combinations of slants generated from the viewpoint-from-above, which was determined by the environmental as well as by the viewer-centered reference frame. PMID:27433329
Raval, Heli S.; Nayak, J. B.; Patel, B. M.; Bhadesiya, C. M.
2015-01-01
Aim: The present study was undertaken to understand the zoonotic importance of canine scabies and dermatophytosis with special reference to the knowledge level of dog owners in urban areas of Gujarat. Materials and Methods: The study was carried out in randomly selected 120 dog owners of 3 urban cities (viz., Ahmedabad, Anand and Vadodara) of Gujarat state, India. Dog owners (i.e., respondents) were subjected to a detailed interview regarding the zoonotic importance of canine scabies and dermatophytosis in dogs. Ex-post-facto research design was selected because of the independent variables of the selected respondent population for the study. The crucial method used in collecting data was a field survey to generate null hypothesis (Ho1). Available data was subjected to statistical analysis. Results: The three independent variables, viz., extension contact (r=0.522**), mass-media exposure (r=0.205*) and management orientation (r=0.264**) had significant relationship with knowledge of dog owners about zoonotic diseases. Other independent variables, viz., education, experience in dog keeping and housing space were observed to have negative and non-significant relationship with knowledge of dog owners about zoonotic diseases. Conclusion: Extension contact, exposure to extension mass-media, management orientation and innovation proneness among dog owners of 3 urban cities of Gujarat state had significant relationship with knowledge of dog owners on zoonotic aspects of canine scabies and dermatophytosis. Data provided new insights on the present status of zoonotic disease-awareness, which would be an aid to plan preventive measures. PMID:27065644
Early Visual Cortex Dynamics during Top-Down Modulated Shifts of Feature-Selective Attention.
Müller, Matthias M; Trautmann, Mireille; Keitel, Christian
2016-04-01
Shifting attention from one color to another color or from color to another feature dimension such as shape or orientation is imperative when searching for a certain object in a cluttered scene. Most attention models that emphasize feature-based selection implicitly assume that all shifts in feature-selective attention underlie identical temporal dynamics. Here, we recorded time courses of behavioral data and steady-state visual evoked potentials (SSVEPs), an objective electrophysiological measure of neural dynamics in early visual cortex to investigate temporal dynamics when participants shifted attention from color or orientation toward color or orientation, respectively. SSVEPs were elicited by four random dot kinematograms that flickered at different frequencies. Each random dot kinematogram was composed of dashes that uniquely combined two features from the dimensions color (red or blue) and orientation (slash or backslash). Participants were cued to attend to one feature (such as color or orientation) and respond to coherent motion targets of the to-be-attended feature. We found that shifts toward color occurred earlier after the shifting cue compared with shifts toward orientation, regardless of the original feature (i.e., color or orientation). This was paralleled in SSVEP amplitude modulations as well as in the time course of behavioral data. Overall, our results suggest different neural dynamics during shifts of attention from color and orientation and the respective shifting destinations, namely, either toward color or toward orientation.
Selective processing of multiple features in the human brain: effects of feature type and salience.
McGinnis, E Menton; Keil, Andreas
2011-02-09
Identifying targets in a stream of items at a given constant spatial location relies on selection of aspects such as color, shape, or texture. Such attended (target) features of a stimulus elicit a negative-going event-related brain potential (ERP), termed Selection Negativity (SN), which has been used as an index of selective feature processing. In two experiments, participants viewed a series of Gabor patches in which targets were defined as a specific combination of color, orientation, and shape. Distracters were composed of different combinations of color, orientation, and shape of the target stimulus. This design allows comparisons of items with and without specific target features. Consistent with previous ERP research, SN deflections extended between 160-300 ms. Data from the subsequent P3 component (300-450 ms post-stimulus) were also examined, and were regarded as an index of target processing. In Experiment A, predominant effects of target color on SN and P3 amplitudes were found, along with smaller ERP differences in response to variations of orientation and shape. Manipulating color to be less salient while enhancing the saliency of the orientation of the Gabor patch (Experiment B) led to delayed color selection and enhanced orientation selection. Topographical analyses suggested that the location of SN on the scalp reliably varies with the nature of the to-be-attended feature. No interference of non-target features on the SN was observed. These results suggest that target feature selection operates by means of electrocortical facilitation of feature-specific sensory processes, and that selective electrocortical facilitation is more effective when stimulus saliency is heightened.
Lhermitte, L; Mejstrikova, E; van der Sluijs-Gelling, A J; Grigore, G E; Sedek, L; Bras, A E; Gaipa, G; Sobral da Costa, E; Novakova, M; Sonneveld, E; Buracchi, C; de Sá Bacelar, T; te Marvelde, J G; Trinquand, A; Asnafi, V; Szczepanski, T; Matarraz, S; Lopez, A; Vidriales, B; Bulsa, J; Hrusak, O; Kalina, T; Lecrevisse, Q; Martin Ayuso, M; Brüggemann, M; Verde, J; Fernandez, P; Burgos, L; Paiva, B; Pedreira, C E; van Dongen, J J M; Orfao, A; van der Velden, V H J
2018-01-01
Precise classification of acute leukemia (AL) is crucial for adequate treatment. EuroFlow has previously designed an AL orientation tube (ALOT) to guide towards the relevant classification panel (T-cell acute lymphoblastic leukemia (T-ALL), B-cell precursor (BCP)-ALL and/or acute myeloid leukemia (AML)) and final diagnosis. Now we built a reference database with 656 typical AL samples (145 T-ALL, 377 BCP-ALL, 134 AML), processed and analyzed via standardized protocols. Using principal component analysis (PCA)-based plots and automated classification algorithms for direct comparison of single-cells from individual patients against the database, another 783 cases were subsequently evaluated. Depending on the database-guided results, patients were categorized as: (i) typical T, B or Myeloid without or; (ii) with a transitional component to another lineage; (iii) atypical; or (iv) mixed-lineage. Using this automated algorithm, in 781/783 cases (99.7%) the right panel was selected, and data comparable to the final WHO-diagnosis was already provided in >93% of cases (85% T-ALL, 97% BCP-ALL, 95% AML and 87% mixed-phenotype AL patients), even without data on the full-characterization panels. Our results show that database-guided analysis facilitates standardized interpretation of ALOT results and allows accurate selection of the relevant classification panels, hence providing a solid basis for designing future WHO AL classifications. PMID:29089646
NASA Astrophysics Data System (ADS)
MacMillan, D. S.
2014-12-01
Galactic aberration is due to the motion of the solar system barycenter around the galactic center. It results in a systematic pattern of apparent proper motion of radio sources observed by VLBI. This effect is not currently included in VLBI analysis. Estimates of the size of this effect indicate that it is important that this secular aberration drift be accounted for in order to maintain an accurate celestial reference frame and allow astrometry at the several microarcsecond level. Future geodetic observing systems are being designed to be capable of producing a future terrestrial reference frame with an accuracy of 1 mm and stability of 0.1 mm/year. We evaluate the effect galactic aberration on attaining these reference frame goals. This presentation will discuss 1) the estimation of galactic aberration from VLBI data and 2) the effect of aberration on the Terrestrial and Celestial Reference Frames and the Earth Orientation Parameters that connect these frames.
Sexual minorities and selection of a primary care physician in a midwestern U.S. city.
Labig, Chalmer E; Peterson, Tim O
2006-01-01
How and why sexual minorities select a primary care physician is critical to the development of methods for attracting these clients to a physician's practice. Data obtained from a sample of sexual minorities in a mid-size city in our nation's heartland would indicate that these patients are loyal when the primary care physician has a positive attitude toward their sexual orientation. The data also confirms that most sexual minorities select same sex physicians but not necessarily same sexual orientation physicians because of lack of knowledge of physicians' sexual orientation. Family practice physicians and other primary care physicians can reach out to this population by encouraging word of mouth advertising and by displaying literature on health issues for all sexual orientations in their offices.
A Study of Parallelism of the Occlusal Plane and Ala-Tragus Line
Sadr, Katayoun; Sadr, Makan
2009-01-01
Background and aims Orientation of the occlusal plane is one of the most important clinical procedures in prostho-dontic rehabilitation of edentulous patients. The aim of this study was to define the best posterior reference point of ala-tragus line for orientation of occlusal plane for complete denture fabrication. Materials and methods Fifty-three dental students (27 females and 26 males) with complete natural dentition and Angel’s Class I occlusal relationship were selected. The subjects were photographed in natural head position while clenching on a Fox plane. After tracing the photographs, the angles between the following lines were measured: the occlusal plane (Fox plane) and the superior border of ala-tragus, the occlusal plane (Fox plane) and the middle of ala-tragus as well as the occlusal plane (Fox plane) and the inferior border of ala-tragus. Descriptive statistics, one sample t-test and independent t-test were used. P value less than 0.05 was considered significant. Results There was no parallelism between the occlusal plane and ala-tragus line with three different posterior ends and one sample t-test showed that the angles between them were significantly different from zero (p<0.05). However, the supe-rior border of ala-tragus line had the lowest mean angle, 1.80° (3.12) and was almost parallel to the occlusal plane. Conclusion The superior border of the tragus is suggested as the posterior reference for ala-tragus line. PMID:23230496
Cross-sensory reference frame transfer in spatial memory: the case of proprioceptive learning.
Avraamides, Marios N; Sarrou, Mikaella; Kelly, Jonathan W
2014-04-01
In three experiments, we investigated whether the information available to visual perception prior to encoding the locations of objects in a path through proprioception would influence the reference direction from which the spatial memory was formed. Participants walked a path whose orientation was misaligned to the walls of the enclosing room and to the square sheet that covered the path prior to learning (Exp. 1) and, in addition, to the intrinsic structure of a layout studied visually prior to walking the path and to the orientation of stripes drawn on the floor (Exps. 2 and 3). Despite the availability of prior visual information, participants constructed spatial memories that were aligned with the canonical axes of the path, as opposed to the reference directions primed by visual experience. The results are discussed in the context of previous studies documenting transfer of reference frames within and across perceptual modalities.
Reference Frames in Earth Rotation Theories
NASA Astrophysics Data System (ADS)
Ferrándiz, José M.; Belda, Santiago; Heinkelmann, Robert; Getino, Juan; Schuh, Harald; Escapa, Alberto
2015-04-01
Nowadays the determination of the Earth Orientation Parameters (EOP) and the different Terrestrial Reference Frames (TRF) are not independent. The available theories of Earth rotation aims at providing the orientation of a certain reference system linked somehow to the Earth with respect to a given celestial system, considered as inertial. In the past years a considerable effort has been dedicated to the improvement of the TRF realizations, following the lines set up in the 1980's. However, the reference systems used in the derivation of the theories have been rather considered as something fully established, not deserving a special attention. In this contribution we review the definitions of the frames used in the main theoretical approaches, focusing on those used in the construction of IAU2000, and the extent to which their underlying hypotheses hold. The results are useful to determine the level of consistency of the predicted and determined EOP.
Collected software engineering papers, volume 9
NASA Technical Reports Server (NTRS)
1991-01-01
This document is a collection of selected technical papers produced by participants in the Software Engineering Laboratory (SEL) from November 1990 through October 1991. The purpose of the document is to make available, in one reference, some results of SEL research that originally appeared in a number of different forums. This is the ninth such volume of technical papers produced by the SEL. Although these papers cover several topics related to software engineering, they do not encompass the entire scope of SEL activities and interests. For the convenience of this presentation, the eight papers contained here are grouped into three major categories: (1) software models studies; (2) software measurement studies; and (3) Ada technology studies. The first category presents studies on reuse models, including a software reuse model applied to maintenance and a model for an organization to support software reuse. The second category includes experimental research methods and software measurement techniques. The third category presents object-oriented approaches using Ada and object-oriented features proposed for Ada. The SEL is actively working to understand and improve the software development process at GSFC.
Language and spatial frames of reference in mind and brain.
Gallistel, C R.
2002-08-01
Some language communities routinely use allocentric reference directions (e.g. 'uphill-downhill') where speakers of European languages would use egocentric references ('left-right'). Previous experiments have suggested that the different language groups use different reference frames in non-linguistic tasks involving the recreation of oriented arrays. However, a recent paper argues that manipulating test conditions produces similar effects in monolingual English speakers, and in animals.
Integration of color, orientation, and size functional domains in the ventral pathway
Ghose, Geoffrey M.; Ts’o, Daniel Y.
2017-01-01
Abstract. Functional specialization within the extrastriate areas of the ventral pathway associated with visual form analysis is poorly understood. Studies comparing the functional selectivities of neurons within the early visual areas have found that there are more similar than different between the areas. We simultaneously imaged visually evoked activation over regions of V2 and V4 and parametrically varied three visual attributes for which selectivity exists in both areas: color, orientation, and size. We found that color selective regions were observed in both areas and were of similar size and spatial distribution. However, two major areal distinctions were observed: V4 contained a greater number and diversity of color-specific regions than V2 and exhibited a higher degree of overlap between domains for different functional attributes. In V2, size and color regions were largely segregated from orientation domains, whereas in V4 both color and size regions overlapped considerably with orientation regions. Our results suggest that higher-order composite selectivities in the extrastriate cortex may arise organically from the interactions afforded by an overlap of functional domains for lower order selectivities. PMID:28573155
Jirmann, Kay-Uwe; Pernberg, Joachim; Eysel, Ulf T
2009-01-01
The role of GABAergic inhibition in orientation and direction selectivity has been investigated with the GABA(A)-Blocker bicuculline in the cat visual cortex, and results indicated a region specific difference of functional contributions of GABAergic inhibition in areas 17 and 18. In area 17 inhibition appeared mainly involved in sculpturing orientation and direction tuning, while in area 18 inhibition seemed more closely associated with temporal receptive field properties. However, different types of stimuli were used to test areas 17 and 18 and further studies performed in area 17 suggested an important influence of the stimulus type (single light bars vs. moving gratings) on the evoked responses (transient vs. sustained) and inhibitory mechanisms (GABA(A) vs. GABA(B)) which in turn might be more decisive for the specific results than the cortical region. To insert the missing link in this chain of arguments it was necessary to study GABAergic inhibition in area 18 with moving light bars, which has not been done so far. Therefore, in the present study we investigated area 18 cells responding to oriented moving light bars with extracellular recordings and reversible microiontophoretic blockade of GABAergig inhibition with bicuculline methiodide. The majority of neurons was characterized by a pronounced orientation specificity and variable degrees of direction selectivity. GABA(A)ergic inhibition significantly influenced preferred orientation and preferred direction in area 18. During the action of bicuculline orientation tuning width increased and orientation and direction selectivity indices decreased. Our results obtained in area 18 with moving bar stimuli, although in the proportion of affected cells similar to those described in area 17, quantitatively matched the findings for direction and orientation specificity obtained with moving gratings in area 18. Accordingly, stimulus type is not decisive in area 18 and the GABA(A) dependent, inhibitory intracortical computations involved in orientation specificity are indeed region-specific and in comparison to area 17 less effective in area 18.
NASA Technical Reports Server (NTRS)
Abbott, Terence S.; Steinmetz, George G.
1987-01-01
A ground-based aircraft simulation study was conducted to determine the effect on pilot performance of replacing the electromechanical altimeter and airspeed indicators with electronically generated representations integrated into the primary flight display via moving-tape (linear moving scale) formats. Several key factors relating to moving-tape formats were examined during the study: tape centering, secondary (trend) information, and tape orientation. The factor of centering refers to whether the tape was centered about the actual airspeed or altitude or about some defined reference value. Tape orientation refers to whether the values represented are arranged in either descending or ascending order. Six pilots participated in this study, with each subject performing 18 runs along a single, known flight profile. Subjective results indicated that the moving-tape formats were generally better than that of the conventional instruments. They also indicated that an actual-centered fixed pointer was preferred to a reference-centered pointer. Performance data for a visual secondary task showed that formats not containing trend information produced better performance; however, no difference was noted in airspeed tracking or altitude tracking performance. Regarding tape orientation, subjective comments indicated that there was lower work load and better performance when the airspeed tape had the high numbers at the top.
Earth Orientation Help - Naval Oceanography Portal
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Sexual orientation and adolescents.
Frankowski, Barbara L
2004-06-01
The American Academy of Pediatrics issued its first statement on homosexuality and adolescents in 1983, with a revision in 1993. This report reflects the growing understanding of youth of differing sexual orientations. Young people are recognizing their sexual orientation earlier than in the past, making this a topic of importance to pediatricians. Pediatricians should be aware that some youths in their care may have concerns about their sexual orientation or that of siblings, friends, parents, relatives, or others. Health care professionals should provide factual, current, nonjudgmental information in a confidential manner. All youths, including those who know or wonder whether they are not heterosexual, may seek information from physicians about sexual orientation, sexually transmitted diseases, substance abuse, or various psychosocial difficulties. The pediatrician should be attentive to various potential psychosocial difficulties, offer counseling or refer for counseling when necessary and ensure that every sexually active youth receives a thorough medical history, physical examination, immunizations, appropriate laboratory tests, and counseling about sexually transmitted diseases (including human immunodeficiency virus infection) and appropriate treatment if necessary. Not all pediatricians may feel able to provide the type of care described in this report. Any pediatrician who is unable to care for and counsel nonheterosexual youth should refer these patients to an appropriate colleague.
An exploration for research-oriented teaching model in biology teaching.
Xing, Wanjin; Mo, Morigen; Su, Huimin
2014-07-01
Training innovative talents, as one of the major aims for Chinese universities, needs to reform the traditional teaching methods. The research-oriented teaching method has been introduced and its connotation and significance for Chinese university teaching have been discussed for years. However, few practical teaching methods for routine class teaching were proposed. In this paper, a comprehensive and concrete research-oriented teaching model with contents of reference value and evaluation method for class teaching was proposed based on the current teacher-guiding teaching model in China. We proposed that the research-oriented teaching model should include at least seven aspects on: (1) telling the scientific history for the skills to find out scientific questions; (2) replaying the experiments for the skills to solve scientific problems; (3) analyzing experimental data for learning how to draw a conclusion; (4) designing virtual experiments for learning how to construct a proposal; (5) teaching the lesson as the detectives solve the crime for learning the logic in scientific exploration; (6) guiding students how to read and consult the relative references; (7) teaching students differently according to their aptitude and learning ability. In addition, we also discussed how to evaluate the effects of the research-oriented teaching model in examination.
The continuous end-state comfort effect: weighted integration of multiple biases.
Herbort, Oliver; Butz, Martin V
2012-05-01
The grasp orientation when grasping an object is frequently aligned in anticipation of the intended rotation of the object (end-state comfort effect). We analyzed grasp orientation selection in a continuous task to determine the mechanisms underlying the end-state comfort effect. Participants had to grasp a box by a circular handle-which allowed for arbitrary grasp orientations-and then had to rotate the box by various angles. Experiments 1 and 2 revealed both that the rotation's direction considerably determined grasp orientations and that end-postures varied considerably. Experiments 3 and 4 further showed that visual stimuli and initial arm postures biased grasp orientations if the intended rotation could be easily achieved. The data show that end-state comfort but also other factors determine grasp orientation selection. A simple mechanism that integrates multiple weighted biases can account for the data.
Yang, Kai-Fu; Li, Chao-Yi; Li, Yong-Jie
2015-01-01
Both the neurons with orientation-selective and with non-selective surround inhibition have been observed in the primary visual cortex (V1) of primates and cats. Though the inhibition coming from the surround region (named as non-classical receptive field, nCRF) has been considered playing critical role in visual perception, the specific role of orientation-selective and non-selective inhibition in the task of contour detection is less known. To clarify above question, we first carried out computational analysis of the contour detection performance of V1 neurons with different types of surround inhibition, on the basis of which we then proposed two integrated models to evaluate their role in this specific perceptual task by combining the two types of surround inhibition with two different ways. The two models were evaluated with synthetic images and a set of challenging natural images, and the results show that both of the integrated models outperform the typical models with orientation-selective or non-selective inhibition alone. The findings of this study suggest that V1 neurons with different types of center–surround interaction work in cooperative and adaptive ways at least when extracting organized structures from cluttered natural scenes. This work is expected to inspire efficient phenomenological models for engineering applications in field of computational machine-vision. PMID:26136664
Yang, Kai-Fu; Li, Chao-Yi; Li, Yong-Jie
2015-01-01
Both the neurons with orientation-selective and with non-selective surround inhibition have been observed in the primary visual cortex (V1) of primates and cats. Though the inhibition coming from the surround region (named as non-classical receptive field, nCRF) has been considered playing critical role in visual perception, the specific role of orientation-selective and non-selective inhibition in the task of contour detection is less known. To clarify above question, we first carried out computational analysis of the contour detection performance of V1 neurons with different types of surround inhibition, on the basis of which we then proposed two integrated models to evaluate their role in this specific perceptual task by combining the two types of surround inhibition with two different ways. The two models were evaluated with synthetic images and a set of challenging natural images, and the results show that both of the integrated models outperform the typical models with orientation-selective or non-selective inhibition alone. The findings of this study suggest that V1 neurons with different types of center-surround interaction work in cooperative and adaptive ways at least when extracting organized structures from cluttered natural scenes. This work is expected to inspire efficient phenomenological models for engineering applications in field of computational machine-vision.
Natural selective attention: Orienting and emotion
BRADLEY, MARGARET M.
2013-01-01
The foundations of orienting and attention are hypothesized to stem from activation of defensive and appetitive motivational systems that evolved to protect and sustain the life of the individual. Motivational activation initiates a cascade of perceptual and motor processes that facilitate the selection of appropriate behavior. Among these are detection of significance, indexed by a late centro-parietal positivity in the event-related potential, enhanced perceptual processing, indexed by a initial cardiac deceleration, and preparation for action, indexed by electrodermal changes. Data exploring the role of stimulus novelty and significance in orienting are presented that indicate different components of the orienting response habituate at different rates. Taken together, it is suggested that orienting is mediated by activation of fundamental motivational systems that have evolved to support survival. PMID:18778317
Characterizing Feature Matching Performance Over Long Time Periods (Author’s Manuscript)
2015-01-05
older imagery. These applications, including approaches to geo-location, geo- orientation [13], geo-tagging [16], landmark recognition [23], image... orientation between features is less than 10 degrees. We calculate the percent of features from the reference image that fit into each of these three...always because the key point detection algorithm did not find feature points at the same locations and orientation . 5. Conclusions In this paper, we offer
Distributed Object Oriented Programming
1990-02-01
of the object oriented model of computation. Therefore, object oriented programming can provide the programmer with good conceptual tools to divide his...LABOR SALES-COMMISSION). The symbol + refers to the addition function and takes any number of numeric arguments. The third subtype of list forms is the...2) ’(:SEND-DONE) (SEWF (AREF OBJECT-i1-MESSAGES-SENT 2) ’(PROGN (FORMAT T "-s methd completely executed instr-ptr -s-V NAME %INSTR-PTR%) (INCF
Combined influence of visual scene and body tilt on arm pointing movements: gravity matters!
Scotto Di Cesare, Cécile; Sarlegna, Fabrice R; Bourdin, Christophe; Mestre, Daniel R; Bringoux, Lionel
2014-01-01
Performing accurate actions such as goal-directed arm movements requires taking into account visual and body orientation cues to localize the target in space and produce appropriate reaching motor commands. We experimentally tilted the body and/or the visual scene to investigate how visual and body orientation cues are combined for the control of unseen arm movements. Subjects were asked to point toward a visual target using an upward movement during slow body and/or visual scene tilts. When the scene was tilted, final pointing errors varied as a function of the direction of the scene tilt (forward or backward). Actual forward body tilt resulted in systematic target undershoots, suggesting that the brain may have overcompensated for the biomechanical movement facilitation arising from body tilt. Combined body and visual scene tilts also affected final pointing errors according to the orientation of the visual scene. The data were further analysed using either a body-centered or a gravity-centered reference frame to encode visual scene orientation with simple additive models (i.e., 'combined' tilts equal to the sum of 'single' tilts). We found that the body-centered model could account only for some of the data regarding kinematic parameters and final errors. In contrast, the gravity-centered modeling in which the body and visual scene orientations were referred to vertical could explain all of these data. Therefore, our findings suggest that the brain uses gravity, thanks to its invariant properties, as a reference for the combination of visual and non-visual cues.
Lebel, Karina; Hamel, Mathieu; Duval, Christian; Nguyen, Hung; Boissy, Patrick
2018-01-01
Joint kinematics can be assessed using orientation estimates from Attitude and Heading Reference Systems (AHRS). However, magnetically-perturbed environments affect the accuracy of the estimated orientations. This study investigates, both in controlled and human mobility conditions, a trial calibration technic based on a 2D photograph with a pose estimation algorithm to correct initial difference in AHRS Inertial reference frames and improve joint angle accuracy. In controlled conditions, two AHRS were solidly affixed onto a wooden stick and a series of static and dynamic trials were performed in varying environments. Mean accuracy of relative orientation between the two AHRS was improved from 24.4° to 2.9° using the proposed correction method. In human conditions, AHRS were placed on the shank and the foot of a participant who performed repeated trials of straight walking and walking while turning, varying the level of magnetic perturbation in the starting environment and the walking speed. Mean joint orientation accuracy went from 6.7° to 2.8° using the correction algorithm. The impact of starting environment was also greatly reduced, up to a point where one could consider it as non-significant from a clinical point of view (maximum mean difference went from 8° to 0.6°). The results obtained demonstrate that the proposed method improves significantly the mean accuracy of AHRS joint orientation estimations in magnetically-perturbed environments and can be implemented in post processing of AHRS data collected during biomechanical evaluation of motion. Copyright © 2017 Elsevier B.V. All rights reserved.
Prieur, J-M; Bourdin, C; Sarès, F; Vercher, J-L
2006-01-01
A major issue in motor control studies is to determine whether and how we use spatial frames of reference to organize our spatially oriented behaviors. In previous experiments we showed that simulated body tilt during off-axis rotation affected the performance in verbal localization and manual pointing tasks. It was hypothesized that the observed alterations were at least partly due to a change in the orientation of the egocentric frame of reference, which was indeed centered on the body but aligned with the gravitational vector. The present experiments were designed to test this hypothesis in a situation where no inertial constraints (except the usual gravitational one) exist and where the orientation of the body longitudinal z-axis was not aligned with the direction of the gravity. Eleven subjects were exposed to real static body tilt and were required to verbally localize (experiment 1) and to point as accurately as possible towards (experiment 2) memorized visual targets, in two conditions, Head-Free and Head-Fixed conditions. Results show that the performance was only affected by real body tilt in the localization task performed when the subject's head was tilted relative to the body. Thus, dissociation between gravity and body longitudinal z-axis alone is not responsible for localization nor for pointing errors. Therefore, the egocentric frame of reference seems independent from the orientation of the gravity with regard to body z-axis as expected from our previous studies. Moreover, the use of spatial referentials appears to be less mandatory than expected for pointing movements (motor task) than for localization task (cognitive task).
Combined Influence of Visual Scene and Body Tilt on Arm Pointing Movements: Gravity Matters!
Scotto Di Cesare, Cécile; Sarlegna, Fabrice R.; Bourdin, Christophe; Mestre, Daniel R.; Bringoux, Lionel
2014-01-01
Performing accurate actions such as goal-directed arm movements requires taking into account visual and body orientation cues to localize the target in space and produce appropriate reaching motor commands. We experimentally tilted the body and/or the visual scene to investigate how visual and body orientation cues are combined for the control of unseen arm movements. Subjects were asked to point toward a visual target using an upward movement during slow body and/or visual scene tilts. When the scene was tilted, final pointing errors varied as a function of the direction of the scene tilt (forward or backward). Actual forward body tilt resulted in systematic target undershoots, suggesting that the brain may have overcompensated for the biomechanical movement facilitation arising from body tilt. Combined body and visual scene tilts also affected final pointing errors according to the orientation of the visual scene. The data were further analysed using either a body-centered or a gravity-centered reference frame to encode visual scene orientation with simple additive models (i.e., ‘combined’ tilts equal to the sum of ‘single’ tilts). We found that the body-centered model could account only for some of the data regarding kinematic parameters and final errors. In contrast, the gravity-centered modeling in which the body and visual scene orientations were referred to vertical could explain all of these data. Therefore, our findings suggest that the brain uses gravity, thanks to its invariant properties, as a reference for the combination of visual and non-visual cues. PMID:24925371
Queer narratives and minority stress: Stories from lesbian, gay and bisexual individuals in Norway.
Synnes, Oddgeir; Malterud, Kirsti
2018-03-01
This study aims to explore how minority stress related to sexual orientation is reflected in narratives from lesbian, gay and bisexual (LGB) individuals in Norway, with an impact for national public health policy. Arthur Frank's dialogical narrative analysis was applied to personal stories from 65 persons self-referring to different categories of queer identities, submitted online anonymously to a Norwegian national archive for queer history. A purposive sample of three different stories were selected due to their capacity to illuminate how various aspects of minority stress are narrated in diverse interplays between individual voices and resources, and cultural scripts and societal influences. Our analysis highlighted how stories may offer significant glimpses into the dynamic and complex fashioning of sexual identities, giving precious clues to the vulnerabilities and strengths of the narrator. Contemporary queer narratives from Norway reflect meaning-making related to sexual orientation that are influenced by, and expand upon, the classical scripts dominated by tragedy and tristesse, personal progress or simply no particular tension. LGB individuals of different ages and backgrounds had experienced aspects of minority stress related to their sexual orientation, with a substantial impact on identity, even when significant others were encouraging. The stories indicate that positive proximal processes, such as personal resilience and sympathetic environments, can support mental health and counteract negative effects of distal processes contributing to minority stress, such as heteronormativity and subtle microaggression. Public health strategies addressing attitudes to sexual orientation among the general population may contribute to diverse affirmative cultural scripts about queer lives, thereby enhancing queer mental health.
Supply-Chain Optimization Template
NASA Technical Reports Server (NTRS)
Quiett, William F.; Sealing, Scott L.
2009-01-01
The Supply-Chain Optimization Template (SCOT) is an instructional guide for identifying, evaluating, and optimizing (including re-engineering) aerospace- oriented supply chains. The SCOT was derived from the Supply Chain Council s Supply-Chain Operations Reference (SCC SCOR) Model, which is more generic and more oriented toward achieving a competitive advantage in business.
Curriculum Reform in Mathematics and the Target Oriented Curriculum.
ERIC Educational Resources Information Center
Fung, Chun Ip
1995-01-01
Highlights issues and ideas in the reform of school mathematics curricula with reference to Australia, the United Kingdom, and the United States. Interprets the ideas set out in documents related to the Target Oriented Curriculum (TOC) initiative in Hong Kong. Discusses factors that hinder the implementation of the TOC. (DSK)
Teachers' Stages of Concern about the Target-Oriented Curriculum.
ERIC Educational Resources Information Center
Cheung, Derek; Ng, Davis
2000-01-01
Investigates teachers' concerns about the Target-Oriented Curriculum (TOC) in Hong Kong (China). Finds that most teachers showed concern about the management of TOC (found in the third stage) and most were concerned with efficiency, time demands, organization, scheduling, and the best use of resources. Includes references. (CMK)
A Cluster Analytic Study of Clinical Orientations among Chemical Dependency Counselors.
ERIC Educational Resources Information Center
Thombs, Dennis L.; Osborn, Cynthia J.
2001-01-01
Three distinct clinical orientations were identified in a sample of chemical dependency counselors (N=406). Based on cluster analysis, the largest group, identified and labeled as "uniform counselors," endorsed a simple, moral-disease model with little interest in psychosocial interventions. (Contains 50 references and 4 tables.) (GCP)
Exploring the Value Orientations of Inuit and White Students: An Empirical Inquiry.
ERIC Educational Resources Information Center
Roberts, Lance W.; And Others
1989-01-01
Finds that, among 46 Inuit and 11 White 10-16-year-old students in the Northwest Territories (Canada), Inuit students had less modern values than their white peers, but Inuit scores varied considerably both within and among the 5 value orientations examined. Contains 34 references. (SV)
Temporal Effects of Alignment in Text-Based, Task-Oriented Discourse
ERIC Educational Resources Information Center
Foltz, Anouschka; Gaspers, Judith; Meyer, Carolin; Thiele, Kristina; Cimiano, Philipp; Stenneken, Prisca
2015-01-01
Communicative alignment refers to adaptation to one's communication partner. Temporal aspects of such alignment have been little explored. This article examines temporal aspects of lexical and syntactic alignment (i.e., tendencies to use the interlocutor's lexical items and syntactic structures) in task-oriented discourse. In particular, we…
Meilinger, Tobias; Frankenstein, Julia; Simon, Nadine; Bülthoff, Heinrich H; Bresciani, Jean-Pierre
2016-02-01
Reference frames in spatial memory encoding have been examined intensively in recent years. However, their importance for recall has received considerably less attention. In the present study, passersby used tags to arrange a configuration map of prominent city center landmarks. It has been shown that such configurational knowledge is memorized within a north-up reference frame. However, participants adjusted their maps according to their body orientations. For example, when participants faced south, the maps were likely to face south-up. Participants also constructed maps along their location perspective-that is, the self-target direction. If, for instance, they were east of the represented area, their maps were oriented west-up. If the location perspective and body orientation were in opposite directions (i.e., if participants faced away from the city center), participants relied on location perspective. The results indicate that reference frames in spatial recall depend on the current situation rather than on the organization in long-term memory. These results cannot be explained by activation spread within a view graph, which had been used to explain similar results in the recall of city plazas. However, the results are consistent with forming and transforming a spatial image of nonvisible city locations from the current location. Furthermore, prior research has almost exclusively focused on body- and environment-based reference frames. The strong influence of location perspective in an everyday navigational context indicates that such a reference frame should be considered more often when examining human spatial cognition.
NASA Astrophysics Data System (ADS)
Ruggles, Clive L. N.
During the 1970s and early 1980s, British archaeoastronomers were striving to bridge the interpretative gulf between the "megalithic observatories" of Alexander Thom and an archaeological mainstream that, generally speaking, was hostile to any mention of astronomy in relation to the megalithic monuments of Neolithic and Early Bronze Age Britain. The Scottish recumbent stone circles (RSCs) came to represent an example where sounder methodology could overcome many of the data selection issues that had beset earlier studies and, with due restraint, produce credible interpretations. Systematic studies of their orientations consistently concluded that the RSCs had a strong lunar connection, and it was widely envisaged that they were the setting for ceremonies associated with the appearance of the moon over the recumbent stone. Other evidence such as the presence of white quartz and the spatial distribution of cupmarks appeared to back up this conclusion. New archaeological investigations since 1999 have challenged and modified these conclusions, confirming in particular that the circles were built to enclose cairns rather than to demarcate open spaces. Yet the restricted pattern of orientations of these structures could only have been achieved by reference to the basic diurnal motions of the skies, and orientation in relation to simple observations of the midsummer moon remains the most likely reading of the alignment evidence taken as a whole. On the other hand, a consideration of the broader context, which includes the nearby Clava cairns, highlights instead the symbolic importance of the sun.
Possible systematics in the VLBI catalogs as seen from Gaia
NASA Astrophysics Data System (ADS)
Liu, N.; Zhu, Z.; Liu, J.-C.
2018-01-01
Aims: In order to investigate the systematic errors in the very long baseline interferometry (VLBI) positions of extragalactic sources (quasars) and the global differences between Gaia and VLBI catalogs, we use the first data release of Gaia (Gaia DR1) quasar positions as the reference and study the positional offsets of the second realization of the International Celestial Reference Frame (ICRF2) and the Goddard VLBI solution 2016a (gsf2016a) catalogs. Methods: We select a sample of 1032 common sources among three catalogs and adopt two methods to represent the systematics: considering the differential orientation (offset) and declination bias; analyzing with the vector spherical harmonics (VSH) functions. Results: Between two VLBI catalogs and Gaia DR1, we find that: i) the estimated orientation is consistent with the alignment accuracy of Gaia DR1 to ICRF, of 0.1 mas, but the southern and northern hemispheres show opposite orientations; ii) the declination bias in the southern hemisphere between Gaia DR1 and ICRF2 is estimated to be +152 μas, much larger than that between Gaia DR1 and gsf2016a which is +34 μas. Between two VLBI catalogs, we find that: i) the rotation component shows that ICRF2 and gsf2016a are generally consistent within 30 μas; ii) the glide component and quadrupole component report two declination-dependent offsets: dipolar deformation of +50 μas along the Z-axis, and quadrupolar deformation of -50 μas that would induce a pattern of sin2δ. Conclusions: The significant declination bias between Gaia DR1 and ICRF2 catalogs reported in previous studies is possibly attributed to the systematic errors of ICRF2 in the southern hemisphere. The global differences between ICRF2 and gsf2016a catalogs imply that possible, mainly declination-dependent systematics exit in the VLBI positions and need further investigations in the future Gaia data release and the next generation of ICRF.
Human centromedian-parafascicular complex signals sensory cues for goal-oriented behavior selection.
Schepers, Inga M; Beck, Anne-Kathrin; Bräuer, Susann; Schwabe, Kerstin; Abdallat, Mahmoud; Sandmann, Pascale; Dengler, Reinhard; Rieger, Jochem W; Krauss, Joachim K
2017-05-15
Experimental research has shown that the centromedian-parafascicular complex (CM-Pf) of the intralaminar thalamus is activated in attentional orienting and processing of behaviorally relevant stimuli. These observations resulted in the hypothesis that the CM-Pf plays a pivotal role in goal-oriented behavior selection. We here set out to test this hypothesis with electrophysiological recordings from patients with electrodes implanted in CM-Pf for deep brain stimulation (DBS) treatment of chronic neuropathic pain. Six patients participated in (1) an auditory three-class oddball experiment, which required a button press to target tones, but not to standard and deviant tones and in (2) a multi-speaker experiment with a target word that required attention selection and a target image that required response selection. Subjects showed transient neural responses (8-15Hz) to the target tone and the target word. Two subjects additionally showed transient neural responses (15-25Hz) to the target image. All sensory target stimuli were related to an internal goal and required a behavior selection (attention selection, response selection). In group analyses, neural responses were greater to target tones than deviant and standard tones and to target words than other task-relevant words that did not require attention selection. The transient neural responses occurred after the target stimuli but prior to the overt behavioral response. Our results demonstrate that in human subjects the CM-Pf is involved in signaling sensory inputs related to goal-oriented selection of behavior. Copyright © 2017 Elsevier Inc. All rights reserved.
Selective attention without a neocortex.
Krauzlis, Richard J; Bogadhi, Amarender R; Herman, James P; Bollimunta, Anil
2018-05-01
Selective attention refers to the ability to restrict neural processing and behavioral responses to a relevant subset of available stimuli, while simultaneously excluding other valid stimuli from consideration. In primates and other mammals, descriptions of this ability typically emphasize the neural processing that takes place in the cerebral neocortex. However, non-mammals such as birds, reptiles, amphibians and fish, which completely lack a neocortex, also have the ability to selectively attend. In this article, we survey the behavioral evidence for selective attention in non-mammals, and review the midbrain and forebrain structures that are responsible. The ancestral forms of selective attention are presumably selective orienting behaviors, such as prey-catching and predator avoidance. These behaviors depend critically on a set of subcortical structures, including the optic tectum (OT), thalamus and striatum, that are highly conserved across vertebrate evolution. In contrast, the contributions of different pallial regions in the forebrain to selective attention have been subject to more substantial changes and reorganization. This evolutionary perspective makes plain that selective attention is not a function achieved de novo with the emergence of the neocortex, but instead is implemented by circuits accrued and modified over hundreds of millions of years, beginning well before the forebrain contained a neocortex. Determining how older subcortical circuits interact with the more recently evolved components in the neocortex will likely be crucial for understanding the complex properties of selective attention in primates and other mammals, and for identifying the etiology of attention disorders. Published by Elsevier Ltd.
NASA Astrophysics Data System (ADS)
Lundegård, Iann
2015-09-01
Today an increasing number of countries around the world have acquired almost the same metaphorical speech about teaching and learning. These theories grown in the Western world are largely produced within the framework of psychology and individualistic oriented educational philosophy and fits with the ever-expanding financial growth paradigm. This article gives a brief reference to an exchange that in the early 1900's took place between two different ways to go in American educational philosophy. Then selects John Dewey's route choice, which took a step away from attempts to create a rationalistic ultimate definition of teaching and learning. Instead, a couple of different metaphors for education are demonstrated that can be used as a basis for pragmatically organizing teaching toward specific purposes and consequences in relation to different cultural traditions.
Pavlovčič, Urban; Diaci, Janez; Možina, Janez; Jezeršek, Matija
2013-09-26
Knowing the orientation of the head is important in many fields, including medicine. Many methods and measuring systems exist, but usually they use different markers or sensors attached to the subject's head for head orientation determination. In certain applications these attachments may represent a burden or a distraction to the subject under study which may have an unfavourable impact on the measurement. We propose a non-contact optical method for head-to-trunk orientation measurement that does not require any attachments to the subject under study. An innovative handheld 3D apparatus has been developed for non-invasive and fast 3D shape measurements. It is based on the triangulation principle in combination with fringe projection. The shape of the subject's upper trunk and head is reconstructed from a single image using the Fourier transform profilometry method. Two shape measurements are required to determine the head-to-trunk orientation angles: one in the reference (neutral) position and the other one in the position of interest. The algorithm for the head-to-trunk orientation angle extraction is based on the separate alignment of the shape of the subject's upper trunk and head against the corresponding shape in the reference pose. Single factor analysis of variance (ANOVA) was used for statistical characterisation of the method precision. The method and the 3D apparatus were verified in-vitro using a mannequin and a reference orientation tracker. The uncertainty of the calculated orientation was 2°. During the in-vivo test with a human subject diagnosed with cervical dystonia (aged 60), the repeatability of the measurements was 3°. In-vitro and in-vivo comparison was done on the basis of an experiment with the mannequin and a healthy male (aged 29). These results show that only the difference between flexion/extension measured angles was statistically significant. The differences between means were less than 1° for all ranges. The new non-contact method enables the compensation of the movement of the measuring instrument or the subject's body as a whole, is non-invasive, requires little additional equipment and causes little stress for the subject and operator. We find that it is appropriate for measurements of the head orientation with respect to the trunk for the characterization of the cervical dystonia.
NASA Astrophysics Data System (ADS)
Sakashita, Tatsuo; Deluca, Marco; Yamamoto, Shinsuke; Chazono, Hirokazu; Pezzotti, Giuseppe
2007-06-01
The stress dependence of the Raman spectrum of polycrystalline barium titanate (BaTiO3, BT) ceramics has been examined with microprobe polarized Raman spectroscopy. The angular dependence of the Raman spectrum of the tetragonal BT crystal has been theoretically established, enabling us to assess the stress dependence of selected spectral modes without the influence of crystallographic domain orientation. Upon considering the frequency shift of selected Raman modes as a function of orientation between the crystallographic axis and the polarization vector of incident and scattered light, a suitable instrumental configuration has been selected, which allowed a direct residual stress measurement according to a modified piezospectroscopic procedure. The analysis is based on the selection of mixed photostimulated spectral modes in two perpendicular angular orientations.
Cultural Orientation and Its Associations with Alcohol Use by University Students in China
Wang, Shiyuan; Shell, Duane F.
2016-01-01
Cultural orientation is defined as an individual’s cultural preferences when encountering imported culture while still living in the native culture. Data was analyzed from 1305 Chinese university students attending universities in Beijing, Kunming, and Wuhan. Cultural orientation was assessed with the Chinese Cultural Orientation Questionnaire, which assesses both Western and Traditional Chinese cultural orientations. The analysis used hierarchical logistic regression with nondrinkers as the reference group and controlling for demographic factors (age, gender, and urban/rural background). Western cultural orientation was found to significantly increase the odds of recent drinking. The results indicated that higher Western cultural orientation was, after gender, the second most important factor associated with Chinese college student drinking frequency. Traditional Chinese cultural orientation was not associated with drinking frequency. This study highlights an unexpected outcome of globalization on students who have not left their home cultures. PMID:27806096
Cultural Orientation and Its Associations with Alcohol Use by University Students in China.
Wang, Shiyuan; Newman, Ian M; Shell, Duane F
2016-01-01
Cultural orientation is defined as an individual's cultural preferences when encountering imported culture while still living in the native culture. Data was analyzed from 1305 Chinese university students attending universities in Beijing, Kunming, and Wuhan. Cultural orientation was assessed with the Chinese Cultural Orientation Questionnaire, which assesses both Western and Traditional Chinese cultural orientations. The analysis used hierarchical logistic regression with nondrinkers as the reference group and controlling for demographic factors (age, gender, and urban/rural background). Western cultural orientation was found to significantly increase the odds of recent drinking. The results indicated that higher Western cultural orientation was, after gender, the second most important factor associated with Chinese college student drinking frequency. Traditional Chinese cultural orientation was not associated with drinking frequency. This study highlights an unexpected outcome of globalization on students who have not left their home cultures.
Hayes, D.B.; Baylis, J.R.; Carl, L.M.; Dodd, H.R.; Goldstein, J.D.; McLaughlin, R.L.; Noakes, D.L.G.; Porto, L.M.
2003-01-01
Four sampling designs for quantifying the effect of low-head sea lamprey (Petromyzon marinus) barriers on fish communities were evaluated, and the contribution of process-oriented research to the overall confidence of results obtained was discussed. The designs include: (1) sample barrier streams post-construction; (2) sample barrier and reference streams post-construction; (3) sample barrier streams pre- and post-construction; and (4) sample barrier and reference streams pre- and post-construction. In the statistical literature, the principal basis for comparison of sampling designs is generally the precision achieved by each design. In addition to precision, designs should be compared based on the interpretability of results and on the scale to which the results apply. Using data collected in a broad survey of streams with and without sea lamprey barriers, some of the tradeoffs that occur among precision, scale, and interpretability are illustrated. Although circumstances such as funding and availability of pre-construction data may limit which design can be implemented, a pre/post-construction design including barrier and reference streams provides the most meaningful information for use in barrier management decisions. Where it is not feasible to obtain pre-construction data, a design including reference streams is important to maintain the interpretability of results. Regardless of the design used, process-oriented research provides a framework for interpreting results obtained in broad surveys. As such, information from both extensive surveys and intensive process-oriented research provides the best basis for fishery management actions, and gives researchers and managers the most confidence in the conclusions reached regarding the effects of sea lamprey barriers.
Aversive learning shapes neuronal orientation tuning in human visual cortex.
McTeague, Lisa M; Gruss, L Forest; Keil, Andreas
2015-07-28
The responses of sensory cortical neurons are shaped by experience. As a result perceptual biases evolve, selectively facilitating the detection and identification of sensory events that are relevant for adaptive behaviour. Here we examine the involvement of human visual cortex in the formation of learned perceptual biases. We use classical aversive conditioning to associate one out of a series of oriented gratings with a noxious sound stimulus. After as few as two grating-sound pairings, visual cortical responses to the sound-paired grating show selective amplification. Furthermore, as learning progresses, responses to the orientations with greatest similarity to the sound-paired grating are increasingly suppressed, suggesting inhibitory interactions between orientation-selective neuronal populations. Changes in cortical connectivity between occipital and fronto-temporal regions mirror the changes in visuo-cortical response amplitudes. These findings suggest that short-term behaviourally driven retuning of human visual cortical neurons involves distal top-down projections as well as local inhibitory interactions.
On the engineering design for systematic integration of agent-orientation in industrial automation.
Yu, Liyong; Schüller, Andreas; Epple, Ulrich
2014-09-01
In today's automation industry, agent-oriented development of system functionalities appears to have a great potential for increasing autonomy and flexibility of complex operations, while lowering the workload of users. In this paper, we present a reference model for the harmonious and systematical integration of agent-orientation in industrial automation. Considering compatibility with existing automation systems and best practice, this model combines advantages of function block technology, service orientation and native description methods from the automation standard IEC 61131-3. This approach can be applied as a guideline for the engineering design of future agent-oriented automation systems. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.
Thermoregulatory behavior and orientation preference in bearded dragons.
Black, Ian R G; Tattersall, Glenn J
2017-10-01
The regulation of body temperature is a critical function for animals. Although reliant on ambient temperature as a heat source, reptiles, and especially lizards, make use of multiple voluntary and involuntary behaviors to thermoregulate, including postural changes in body orientation, either toward or away from solar sources of heat. This thermal orientation may also result from a thermoregulatory drive to maintain precise control over cranial temperatures or a rostrally-driven sensory bias. The purpose of this work was to examine thermal orientation behavior in adult and neonatal bearded dragons (Pogona vitticeps), to ascertain its prevalence across different life stages within a laboratory situation and its interaction with behavioral thermoregulation. Both adult and neonatal bearded dragons were placed in a thermal gradient and allowed to voluntarily select temperatures for up to 8h to observe the presence and development of a thermoregulatory orientation preference. Both adult and neonatal dragons displayed a non-random orientation, preferring to face toward a heat source while achieving mean thermal preferences of ~ 33-34°C. Specifically, adult dragons were more likely to face a heat source when at cooler ambient temperatures and less likely at warmer temperatures, suggesting that orientation behavior counter-balances local selected temperatures but contributes to their thermoregulatory response. Neonates were also more likely to select cooler temperatures when facing a heat source, but required more experience before this orientation behavior emerged. Combined, these results demonstrate the importance of orientation to behavioral thermoregulation in multiple life stages of bearded dragons. Copyright © 2017 Elsevier Ltd. All rights reserved.
Gyhlesten Back, Jessica; Engberg, Göran
2017-01-01
Crystallographic reconstruction of parent austenite grain boundaries from the martensitic microstructure in a wear resistant steel was carried out using electron backscattered diffraction (EBSD). The present study mainly aims to investigate the parent austenite grains from the martensitic structure in an as-rolled (reference) steel sample and samples obtained by quenching at different cooling rates with corresponding dilatometry. Subsequently, this study is to correlate the nearest cooling rate by the dilatometer which yields a similar orientation relationship and substructure as the reference sample. The Kurdjumov-Sachs orientation relationship was used to reconstruct the parent austenite grain boundaries from the martensite boundaries in both reference and dilatometric samples using EBSD crystallographic data. The parent austenite grain boundaries were successfully evaluated from the EBSD data and the corresponding grain sizes were measured. The parent austenite grain boundaries of the reference sample match the sample quenched at 100 °C/s (CR100). Also the martensite substructures and crystallographic textures are similar in these two samples. The results from hardness measurements show that the reference sample exhibits higher hardness than the CR100 sample due to the presence of carbides in the reference sample. PMID:28772813
Gyhlesten Back, Jessica; Engberg, Göran
2017-04-26
Crystallographic reconstruction of parent austenite grain boundaries from the martensitic microstructure in a wear resistant steel was carried out using electron backscattered diffraction (EBSD). The present study mainly aims to investigate the parent austenite grains from the martensitic structure in an as-rolled (reference) steel sample and samples obtained by quenching at different cooling rates with corresponding dilatometry. Subsequently, this study is to correlate the nearest cooling rate by the dilatometer which yields a similar orientation relationship and substructure as the reference sample. The Kurdjumov-Sachs orientation relationship was used to reconstruct the parent austenite grain boundaries from the martensite boundaries in both reference and dilatometric samples using EBSD crystallographic data. The parent austenite grain boundaries were successfully evaluated from the EBSD data and the corresponding grain sizes were measured. The parent austenite grain boundaries of the reference sample match the sample quenched at 100 °C/s (CR100). Also the martensite substructures and crystallographic textures are similar in these two samples. The results from hardness measurements show that the reference sample exhibits higher hardness than the CR100 sample due to the presence of carbides in the reference sample.
Observation-Oriented Modeling: Going beyond "Is It All a Matter of Chance"?
ERIC Educational Resources Information Center
Grice, James W.; Yepez, Maria; Wilson, Nicole L.; Shoda, Yuichi
2017-01-01
An alternative to null hypothesis significance testing is presented and discussed. This approach, referred to as observation-oriented modeling, is centered on model building in an effort to explicate the structures and processes believed to generate a set of observations. In terms of analysis, this novel approach complements traditional methods…
Basic Needs and the Development of Interest and Intrinsic Motivational Orientations
ERIC Educational Resources Information Center
Krapp, Andreas
2005-01-01
From the perspective of the ''person-object-theory of interest'' (POI) the development of interest and interest-related motivational orientations can be explained at the level of functional principles by referring to a dual regulation system that consists of both, cognitive-rational and partly subconscious emotional control mechanisms. Within this…
Lunar Data Information Center: A Shortcut to the Riddle of the Moon
ERIC Educational Resources Information Center
Waranius, Frances B.; Heiken, Jody H.
1975-01-01
The Lunar Data Information Center is a reference and lending collection for researchers, educators, and students of lunar science, worldwide. Such methods as a classification scheme for mission-oriented documentation, sample photo browse files, lunar feature index, and color coding have resulted in a user-oriented collection. Search capability is…
ERIC Educational Resources Information Center
Towler, Annette
2009-01-01
This study focuses on trainer expressiveness and trainee mastery orientation within the context of the seductive details effect. The seductive details effect refers to inclusion of "highly interesting and entertaining information that is only tangentially related to the topic" (Harp & Mayer, 1998, p. 1). One hundred thirty-two participants…
ERIC Educational Resources Information Center
Sleight, Christine C.; Prinz, Philip M.
1985-01-01
Forty language-disordered and nondisordered elementary children viewed a nonverbal film, wrote the story, and narrated it to language-disordered and nondisordered peers unfamiliar with the film. Language-disordered Ss made fewer references to the orientation clauses of props and activities than nondisordered Ss. Neither group modified their…
Correction of radiographic measurements of acetabular cup wear for variations in pelvis orientation.
Derbyshire, Brian
2018-03-01
Radiographic measurement of two-dimensional acetabular cup wear is usually carried out on a series of follow-up radiographs of the patient's pelvis. Since the orientation of the pelvis might not be consistent at every X-ray examination, the resulting change in view of the wear plane introduces error into the linear wear measurement. This effect is amplified on some designs of cup in which the centre of the socket is several millimetres below the centre of the cup or circular wire marker. This study describes the formulation of a mathematical method to correct radiographic wear measurements for changes in pelvis orientation. A mathematical simulation of changes in cup orientation and wear vectors caused by pelvic tilt was used to confirm that the formulae corrected the wear exactly if the radiographic plane of the reference radiograph was parallel to the true plane of wear. An error analysis showed that even when the true wear plane was not parallel to the reference radiographic plane, the formulae could still provide a useful correction. A published correction formula was found to be ineffective.
Correction of radiographic measurements of acetabular cup wear for variations in pelvis orientation
Derbyshire, Brian
2018-01-01
Radiographic measurement of two-dimensional acetabular cup wear is usually carried out on a series of follow-up radiographs of the patient’s pelvis. Since the orientation of the pelvis might not be consistent at every X-ray examination, the resulting change in view of the wear plane introduces error into the linear wear measurement. This effect is amplified on some designs of cup in which the centre of the socket is several millimetres below the centre of the cup or circular wire marker. This study describes the formulation of a mathematical method to correct radiographic wear measurements for changes in pelvis orientation. A mathematical simulation of changes in cup orientation and wear vectors caused by pelvic tilt was used to confirm that the formulae corrected the wear exactly if the radiographic plane of the reference radiograph was parallel to the true plane of wear. An error analysis showed that even when the true wear plane was not parallel to the reference radiographic plane, the formulae could still provide a useful correction. A published correction formula was found to be ineffective. PMID:29473454
Selection of medical students according to their moral orientation.
Bore, Miles; Munro, Don; Kerridge, Ian; Powis, David
2005-03-01
Consideration has been given to the use of tests of moral reasoning in the selection procedure for medical students. We argue that moral orientation, rather than moral reasoning, might be more efficacious in minimising the likelihood of inappropriate ethical behaviour in medicine. A conceptualisation and measure of moral orientation are presented, together with findings from 11 samples of medical school applicants and students. To provide empirical evidence for the reliability and validity of a measure of moral orientation and to explore gender, age, cultural and educational influences on moral orientation. A questionnaire designed to measure a libertarian-dual-communitarian dimension of moral orientation was completed by 7864 medical school applicants and students in Australia, Israel, Fiji, New Zealand, Scotland and England and by 84 Australian psychology students between 1997 and 2001. Older respondents produced marginally higher (more communitarian) moral orientation scores, as did women compared to men. Minor but significant (P <0.05) cultural differences were found. The Israeli samples produced higher mean moral orientation scores, while the Australian psychology student sample produced a lower (more libertarian) mean score relative to all other samples. No significant change in moral orientation score was observed after 1 year in a sample of Australian medical school students (n=59), although some differences observed between 5 cohorts of Australian medical students (Years 1-5; n=234) did reach significance. Moral orientation scores were found to be significantly correlated with a number of personality measures, providing evidence of construct validity. In all samples moral orientation significantly predicted the moral decisions made in response to the hypothetical dilemmas embedded in the measurement instrument. Discussion The results provide support for the conceptualisation of a libertarian-dual-communitarian dimension of moral orientation and demonstrate the psychometric properties of the measurement instrument. A number of questions concerning the use of such tests in selection procedures are considered.
Viswanathan, Sivaram; Jayakumar, Jaikishan; Vidyasagar, Trichur R
2015-09-01
Responses of most neurons in the primary visual cortex of mammals are markedly selective for stimulus orientation and their orientation tuning does not vary with changes in stimulus contrast. The basis of such contrast invariance of orientation tuning has been shown to be the higher variability in the response for low-contrast stimuli. Neurons in the lateral geniculate nucleus (LGN), which provides the major visual input to the cortex, have also been shown to have higher variability in their response to low-contrast stimuli. Parallel studies have also long established mild degrees of orientation selectivity in LGN and retinal cells. In our study, we show that contrast invariance of orientation tuning is already present in the LGN. In addition, we show that the variability of spike responses of LGN neurons increases at lower stimulus contrasts, especially for non-preferred orientations. We suggest that such contrast- and orientation-sensitive variability not only explains the contrast invariance observed in the LGN but can also underlie the contrast-invariant orientation tuning seen at the level of the primary visual cortex. © 2015 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.
Carter, Rona; Silverman, Wendy K.; Jaccard, James
2011-01-01
This study evaluated whether pubertal development and gender role orientation (i.e., masculinity and femininity) can partially explain sex variations in youth anxiety symptoms among clinic referred anxious youth (N = 175; ages 9-13 years; 74% Hispanic; 48% female). Using youth and parent ratings of youth anxiety symptoms, structural equation modeling results indicated that youth who reported being more advanced in their pubertal development reported high levels of femininity and anxiety symptoms. Youth who reported high levels of masculinity had low levels of anxiety symptoms as reported by both youths and parents. The estimated effects of pubertal development, femininity, and masculinity on youth and parent ratings of youth anxiety symptoms were not significantly moderated by biological sex. Pubertal development and gender role orientation appear to be important in explaining levels of youth anxiety symptoms among clinic referred anxious youth. PMID:21916691
Carter, Rona; Silverman, Wendy K; Jaccard, James
2011-01-01
This study evaluated whether pubertal development and gender role orientation (i.e., masculinity and femininity) can partially explain sex variations in youth anxiety symptoms among clinic-referred anxious youth (N = 175; ages 9-13 years; 74% Hispanic; 48% female). Using youth and parent ratings of youth anxiety symptoms, structural equation modeling results indicated that youth who reported being more advanced in their pubertal development reported high levels of femininity and anxiety symptoms. Youth who reported high levels of masculinity had low levels of anxiety symptoms as reported by both youths and parents. The estimated effects of pubertal development, femininity, and masculinity on youth and parent ratings of youth anxiety symptoms were not significantly moderated by biological sex. Pubertal development and gender role orientation appear to be important in explaining levels of youth anxiety symptoms among clinic-referred anxious youth.
Early valproic acid exposure alters functional organization in the primary visual cortex
Pohl-Guimaraes, Fernanda; Krahe, Thomas E.; Medina, Alexandre E.
2018-01-01
Epilepsy is one of the most common neurologic disorders and affects 0.5 to 1% of pregnant women. The use of antiepileptic drugs, which is usually continued throughout pregnancy, can cause in offspring mild to severe sensory deficits. Neuronal selectivity to stimulus orientation is a basic functional property of the visual cortex that is crucial for perception of shapes and borders. Here we investigate the effects of early exposure to valproic acid (Val) and levetiracetam (Lev), commonly used antiepileptic drugs, on the development of cortical neuron orientation selectivity and organization of cortical orientation columns. Ferrets pups were exposed to Val (200 mg/kg), Lev (100 mg/kg) or saline every other day between postnatal day (P) 10 and P30, a period roughly equivalent to the third trimester of human gestation. Optical imaging of intrinsic signals or single-unit recordings were examined at P42–P84, when orientation selectivity in the ferret cortex has reached a mature state. Optical imaging of intrinsic signals revealed decreased contrast of orientation maps in Val-but not Lev- or saline-treated animals. Moreover, single-unit recordings revealed that early Val treatment also reduced orientation selectivity at the cellular level. These findings indicate that Val exposure during a brief period of development disrupts cortical processing of sensory information at a later age and suggest a neurobiological substrate for some types of sensory deficits in fetal anticonvulsant syndrome. PMID:21215743
Early valproic acid exposure alters functional organization in the primary visual cortex.
Pohl-Guimaraes, Fernanda; Krahe, Thomas E; Medina, Alexandre E
2011-03-01
Epilepsy is one of the most common neurologic disorders and affects 0.5 to 1% of pregnant women. The use of antiepileptic drugs, which is usually continued throughout pregnancy, can cause in offspring mild to severe sensory deficits. Neuronal selectivity to stimulus orientation is a basic functional property of the visual cortex that is crucial for perception of shapes and borders. Here we investigate the effects of early exposure to valproic acid (Val) and levetiracetam (Lev), commonly used antiepileptic drugs, on the development of cortical neuron orientation selectivity and organization of cortical orientation columns. Ferrets pups were exposed to Val (200mg/kg), Lev (100mg/kg) or saline every other day between postnatal day (P) 10 and P30, a period roughly equivalent to the third trimester of human gestation. Optical imaging of intrinsic signals or single-unit recordings were examined at P42-P84, when orientation selectivity in the ferret cortex has reached a mature state. Optical imaging of intrinsic signals revealed decreased contrast of orientation maps in Val- but not Lev- or saline-treated animals. Moreover, single-unit recordings revealed that early Val treatment also reduced orientation selectivity at the cellular level. These findings indicate that Val exposure during a brief period of development disrupts cortical processing of sensory information at a later age and suggest a neurobiological substrate for some types of sensory deficits in fetal anticonvulsant syndrome. Copyright © 2011 Elsevier Inc. All rights reserved.
Klein, Brennan J; Li, Zhi; Durgin, Frank H
2016-04-01
What is the natural reference frame for seeing large-scale spatial scenes in locomotor action space? Prior studies indicate an asymmetric angular expansion in perceived direction in large-scale environments: Angular elevation relative to the horizon is perceptually exaggerated by a factor of 1.5, whereas azimuthal direction is exaggerated by a factor of about 1.25. Here participants made angular and spatial judgments when upright or on their sides to dissociate egocentric from allocentric reference frames. In Experiment 1, it was found that body orientation did not affect the magnitude of the up-down exaggeration of direction, suggesting that the relevant orientation reference frame for this directional bias is allocentric rather than egocentric. In Experiment 2, the comparison of large-scale horizontal and vertical extents was somewhat affected by viewer orientation, but only to the extent necessitated by the classic (5%) horizontal-vertical illusion (HVI) that is known to be retinotopic. Large-scale vertical extents continued to appear much larger than horizontal ground extents when observers lay sideways. When the visual world was reoriented in Experiment 3, the bias remained tied to the ground-based allocentric reference frame. The allocentric HVI is quantitatively consistent with differential angular exaggerations previously measured for elevation and azimuth in locomotor space. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
Klein, Brennan J.; Li, Zhi; Durgin, Frank H.
2015-01-01
What is the natural reference frame for seeing large-scale spatial scenes in locomotor action space? Prior studies indicate an asymmetric angular expansion in perceived direction in large-scale environments: Angular elevation relative to the horizon is perceptually exaggerated by a factor of 1.5, whereas azimuthal direction is exaggerated by a factor of about 1.25. Here participants made angular and spatial judgments when upright or on their sides in order to dissociate egocentric from allocentric reference frames. In Experiment 1 it was found that body orientation did not affect the magnitude of the up-down exaggeration of direction, suggesting that the relevant orientation reference frame for this directional bias is allocentric rather than egocentric. In Experiment 2, the comparison of large-scale horizontal and vertical extents was somewhat affected by viewer orientation, but only to the extent necessitated by the classic (5%) horizontal-vertical illusion (HVI) that is known to be retinotopic. Large-scale vertical extents continued to appear much larger than horizontal ground extents when observers lay sideways. When the visual world was reoriented in Experiment 3, the bias remained tied to the ground-based allocentric reference frame. The allocentric HVI is quantitatively consistent with differential angular exaggerations previously measured for elevation and azimuth in locomotor space. PMID:26594884
An adaptable neuromorphic model of orientation selectivity based on floating gate dynamics
Gupta, Priti; Markan, C. M.
2014-01-01
The biggest challenge that the neuromorphic community faces today is to build systems that can be considered truly cognitive. Adaptation and self-organization are the two basic principles that underlie any cognitive function that the brain performs. If we can replicate this behavior in hardware, we move a step closer to our goal of having cognitive neuromorphic systems. Adaptive feature selectivity is a mechanism by which nature optimizes resources so as to have greater acuity for more abundant features. Developing neuromorphic feature maps can help design generic machines that can emulate this adaptive behavior. Most neuromorphic models that have attempted to build self-organizing systems, follow the approach of modeling abstract theoretical frameworks in hardware. While this is good from a modeling and analysis perspective, it may not lead to the most efficient hardware. On the other hand, exploiting hardware dynamics to build adaptive systems rather than forcing the hardware to behave like mathematical equations, seems to be a more robust methodology when it comes to developing actual hardware for real world applications. In this paper we use a novel time-staggered Winner Take All circuit, that exploits the adaptation dynamics of floating gate transistors, to model an adaptive cortical cell that demonstrates Orientation Selectivity, a well-known biological phenomenon observed in the visual cortex. The cell performs competitive learning, refining its weights in response to input patterns resembling different oriented bars, becoming selective to a particular oriented pattern. Different analysis performed on the cell such as orientation tuning, application of abnormal inputs, response to spatial frequency and periodic patterns reveal close similarity between our cell and its biological counterpart. Embedded in a RC grid, these cells interact diffusively exhibiting cluster formation, making way for adaptively building orientation selective maps in silicon. PMID:24765062
ERIC Educational Resources Information Center
Freeman, Mark S.; Hayes, B. Grant; Kuch, Tyson H.; Taub, Gordon
2007-01-01
Selecting a single psychotherapeutic orientation can be a challenge for counselor education students. The authors examined the relationship between counseling theory selection and personality variables of students enrolled in a counseling theories course. A discriminant function analysis was used to identify the personality traits that would…
Visuospatial Orientational Shifts: Evidence for Three Independent Mechanisms.
ERIC Educational Resources Information Center
Noonan, Michael; Axelrod, Seymour
While it is often assumed that a single mechanism underlies varied experimental evidences of selectivity, Berlyne (1969) suggested that attention-like selectivity may take place in a number of quite separate neural systems. This study examined the issue of visuospatial attention by investigating covert orientation or "looking out of the corner of…
NASA Astrophysics Data System (ADS)
Martín-González, Fidel; Martín-Velazquez, Silvia; Rodrigez-Pascua, Miguel Angel; Pérez-López, Raul; Silva, Pablo
2014-05-01
The intensity scales determined the damage caused by an earthquake. However, a new methodology takes into account not only the damage but the type of damage "Earthquake Archaeological Effects", EAE's, and its orientation (e.g. displaced masonry blocks, conjugated fractures, fallen and oriented columns, impact marks, dipping broken corners, etc.) (Rodriguez-Pascua et al., 2011; Giner-Robles et al., 2012). Its main contribution is that it focuses not only on the amount of damage but also in its orientation, giving information about the ground motion during the earthquake. Therefore, this orientations and instrumental data can be correlated with historical earthquakes. In 2011 an earthquake of magnitude Mw 5.2 took place in Lorca (SE Spain) (9 casualties and 460 million Euros in reparations). The study of the EAE's was carried out through the whole city (Giner-Robles et al., 2012). The present study aimed to a.- validate the EAE's methodology using it only in a small place, specifically the cemetery of San Clemente in Lorca, and b.- constraining the range of orientation for each EAE's. This cemetery has been selected because these damage orientation data can be correlated with instrumental information available, and also because this place has: a.- wide variety of architectural styles (neogothic, neobaroque, neoarabian), b.- its Cultural Interest (BIC), and c.- different building materials (brick, limestone, marble). The procedure involved two main phases: a.- inventory and identification of damage (EAE's) by pictures, and b.- analysis of the damage orientations. The orientation was calculated for each EAE's and plotted in maps. Results are NW-SE damage orientation. This orientation is consistent with that recorded in the accelerometer of Lorca (N160°E) and with that obtained from the analysis of EAE's for the whole town of Lorca (N130°E) (Giner-Robles et al., 2012). Due to the existence of an accelerometer, we know the orientation of the peak ground acceleration and we have been able to constrain the ranges of orientation for each EAE's. The orientation of the damage is not usually recorded after an earthquake; however, it can provide information on seismic source in historical earthquakes. References Giner-Robles, J. L., Perez-Lopez, R., Silva Barroso, P., Rodriguez-Pascua, M. A., Martin-Gonzalez, F. and Cabanas, L. 2012. Analisis estructural de danos orientados en el terremoto de Lorca del 11 de mayo de 2011. Aplicaciones en arqueosismologia. Boletín Geológico y Minero, 123 (4): 503-513 Rodriguez-Pascua, M.A., Perez-Lopez, R., Silva, P.G., Giner- Robles, J.L., Garduno-Monroy, V.H. and Reicherter, K. 2011. A Comprehensive Classification of Earthquake Archaeological Effects (EAE) for Archaeoseismology. Quaternary International, 242, 20-30.
Controlled placement and orientation of nanostructures
Zettl, Alex K; Yuzvinsky, Thomas D; Fennimore, Adam M
2014-04-08
A method for controlled deposition and orientation of molecular sized nanoelectromechanical systems (NEMS) on substrates is disclosed. The method comprised: forming a thin layer of polymer coating on a substrate; exposing a selected portion of the thin layer of polymer to alter a selected portion of the thin layer of polymer; forming a suspension of nanostructures in a solvent, wherein the solvent suspends the nanostructures and activates the nanostructures in the solvent for deposition; and flowing a suspension of nanostructures across the layer of polymer in a flow direction; thereby: depositing a nanostructure in the suspension of nanostructures only to the selected portion of the thin layer of polymer coating on the substrate to form a deposited nanostructure oriented in the flow direction. By selectively employing portions of the method above, complex NEMS may be built of simpler NEMSs components.
Willke, Richard J; Zheng, Zhiyuan; Subedi, Prasun; Althin, Rikard; Mullins, C Daniel
2012-12-13
Implicit in the growing interest in patient-centered outcomes research is a growing need for better evidence regarding how responses to a given intervention or treatment may vary across patients, referred to as heterogeneity of treatment effect (HTE). A variety of methods are available for exploring HTE, each associated with unique strengths and limitations. This paper reviews a selected set of methodological approaches to understanding HTE, focusing largely but not exclusively on their uses with randomized trial data. It is oriented for the "intermediate" outcomes researcher, who may already be familiar with some methods, but would value a systematic overview of both more and less familiar methods with attention to when and why they may be used. Drawing from the biomedical, statistical, epidemiological and econometrics literature, we describe the steps involved in choosing an HTE approach, focusing on whether the intent of the analysis is for exploratory, initial testing, or confirmatory testing purposes. We also map HTE methodological approaches to data considerations as well as the strengths and limitations of each approach. Methods reviewed include formal subgroup analysis, meta-analysis and meta-regression, various types of predictive risk modeling including classification and regression tree analysis, series of n-of-1 trials, latent growth and growth mixture models, quantile regression, and selected non-parametric methods. In addition to an overview of each HTE method, examples and references are provided for further reading.By guiding the selection of the methods and analysis, this review is meant to better enable outcomes researchers to understand and explore aspects of HTE in the context of patient-centered outcomes research.
Single-chip microcomputer application in high-altitude balloon orientation system
NASA Technical Reports Server (NTRS)
Lim, T. S.; Ehrmann, C. H.; Allison, S. R.
1980-01-01
This paper describes the application of a single-chip microcomputer in a high-altitude balloon instrumentation system. The system, consisting of a magnetometer, a stepping motor, a microcomputer and a gray code shaft encoder, is used to provide an orientation reference to point a scientific instrument at an object in space. The single-chip microcomputer, Intel's 8748, consisting of a CPU, program memory, data memory and I/O ports, is used to control the orientation of the system.
ERIC Educational Resources Information Center
Chan, Matthew
2017-01-01
This study provides an overview and a snapshot of new student orientation (NSO) and new student e-orientation (NSEO) programs, with a focus on the content and feature analysis of the NSEOs. It offers an overview of currently available NSO programs of 100 randomly selected community colleges from a master list of nearly 900 community colleges in…
Method for Statically Checking an Object-oriented Computer Program Module
NASA Technical Reports Server (NTRS)
Bierhoff, Kevin M. (Inventor); Aldrich, Jonathan (Inventor)
2012-01-01
A method for statically checking an object-oriented computer program module includes the step of identifying objects within a computer program module, at least one of the objects having a plurality of references thereto, possibly from multiple clients. A discipline of permissions is imposed on the objects identified within the computer program module. The permissions enable tracking, from among a discrete set of changeable states, a subset of states each object might be in. A determination is made regarding whether the imposed permissions are violated by a potential reference to any of the identified objects. The results of the determination are output to a user.
Common lines modeling for reference free Ab-initio reconstruction in cryo-EM.
Greenberg, Ido; Shkolnisky, Yoel
2017-11-01
We consider the problem of estimating an unbiased and reference-free ab initio model for non-symmetric molecules from images generated by single-particle cryo-electron microscopy. The proposed algorithm finds the globally optimal assignment of orientations that simultaneously respects all common lines between all images. The contribution of each common line to the estimated orientations is weighted according to a statistical model for common lines' detection errors. The key property of the proposed algorithm is that it finds the global optimum for the orientations given the common lines. In particular, any local optima in the common lines energy landscape do not affect the proposed algorithm. As a result, it is applicable to thousands of images at once, very robust to noise, completely reference free, and not biased towards any initial model. A byproduct of the algorithm is a set of measures that allow to asses the reliability of the obtained ab initio model. We demonstrate the algorithm using class averages from two experimental data sets, resulting in ab initio models with resolutions of 20Å or better, even from class averages consisting of as few as three raw images per class. Copyright © 2017 Elsevier Inc. All rights reserved.
Chen, Hsin-Chen; Jia, Wenyan; Yue, Yaofeng; Li, Zhaoxin; Sun, Yung-Nien; Fernstrom, John D.; Sun, Mingui
2013-01-01
Dietary assessment is important in health maintenance and intervention in many chronic conditions, such as obesity, diabetes, and cardiovascular disease. However, there is currently a lack of convenient methods for measuring the volume of food (portion size) in real-life settings. We present a computational method to estimate food volume from a single photographical image of food contained in a typical dining plate. First, we calculate the food location with respect to a 3D camera coordinate system using the plate as a scale reference. Then, the food is segmented automatically from the background in the image. Adaptive thresholding and snake modeling are implemented based on several image features, such as color contrast, regional color homogeneity and curve bending degree. Next, a 3D model representing the general shape of the food (e.g., a cylinder, a sphere, etc.) is selected from a pre-constructed shape model library. The position, orientation and scale of the selected shape model are determined by registering the projected 3D model and the food contour in the image, where the properties of the reference are used as constraints. Experimental results using various realistically shaped foods with known volumes demonstrated satisfactory performance of our image based food volume measurement method even if the 3D geometric surface of the food is not completely represented in the input image. PMID:24223474
NASA Astrophysics Data System (ADS)
Chen, Hsin-Chen; Jia, Wenyan; Yue, Yaofeng; Li, Zhaoxin; Sun, Yung-Nien; Fernstrom, John D.; Sun, Mingui
2013-10-01
Dietary assessment is important in health maintenance and intervention in many chronic conditions, such as obesity, diabetes and cardiovascular disease. However, there is currently a lack of convenient methods for measuring the volume of food (portion size) in real-life settings. We present a computational method to estimate food volume from a single photographic image of food contained on a typical dining plate. First, we calculate the food location with respect to a 3D camera coordinate system using the plate as a scale reference. Then, the food is segmented automatically from the background in the image. Adaptive thresholding and snake modeling are implemented based on several image features, such as color contrast, regional color homogeneity and curve bending degree. Next, a 3D model representing the general shape of the food (e.g., a cylinder, a sphere, etc) is selected from a pre-constructed shape model library. The position, orientation and scale of the selected shape model are determined by registering the projected 3D model and the food contour in the image, where the properties of the reference are used as constraints. Experimental results using various realistically shaped foods with known volumes demonstrated satisfactory performance of our image-based food volume measurement method even if the 3D geometric surface of the food is not completely represented in the input image.
ERIC Educational Resources Information Center
Badertscher, James A.
This bulletin is designed to provide an overview of teacher orientation practices and suggestions. Its primary audience is the building principals who find themselves responsible for orientation activities. The contents are based on extensive literature reviews, orientation materials and methods used by several selected Oregon school districts,…
NASA Technical Reports Server (NTRS)
Folkner, W. M.; Charlot, P.; Finger, M. H.; Williams, J. G.; Sovers, O. J.; Newhall, XX; Standish, E. M., Jr.
1994-01-01
Very Long Baseline Interferometry (VLBI) observations of extragalactic radio sources provide the basis for defining an accurate non-rotating reference frame in terms of angular positions of the sources. Measurements of the distance from the Earth to the Moon and to the inner planets provide the basis for defining an inertial planetary ephemeris reference frame. The relative orientation, or frame tie, between these two reference frames is of interest for combining Earth orientation measurements, for comparing Earth orientation results with theories referred to the mean equator and equinox, and for determining the positions of the planets with respect to the extragalactic reference frame. This work presents an indirect determination of the extragalactic-planetary frame tie from a combined reduction of VLBI and Lunar Laser Ranging (LLR) observations. For this determination, data acquired by LLR tracking stations since 1969 have been analyzed and combined with 14 years of VLBI data acquired by NASA's Deep Space Network since 1978. The frame tie derived from this joint analysis, with an accuracy of 0.003 sec, is the most accurate determination obtained so far. This result, combined with a determination of the mean ecliptic (defined in the rotating sense), shows that the mean equinox of epoch J2000 is offset from the x-axis of the extragalactic frame adopted by the International Earth Rotation Service for astrometric and geodetic applications by 0.078 sec +/- 0.010 sec along the y-direction and y 0.019 sec +/- 0.001 sec. along the z-direction.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Doug Blankenship
Natural fracture data from wells 33-7, 33A-7,52A-7, 52B-7 and 83-11 at West Flank. Fracture orientations were determined from image logs of these wells (see accompanying submissions). Data files contain depth, apparent (in wellbore reference frame) and true (in geographic reference frame) azimuth and dip, respectively.
NASA Astrophysics Data System (ADS)
He, Hong-Sen; Zhang, Ming-Ming; Dong, Jun; Ueda, Ken-Ichi
2016-12-01
A tilted, linearly polarized laser diode end-pumped Cr4+:YAG passively Q-switched a-cut Nd:YVO4 microchip laser for generating numerous Ince-Gaussian (IG) laser modes with controllable orientations has been demonstrated by selecting the crystalline orientation of an a-cut Nd:YVO4 crystal. The same IG laser mode with different orientations has been achieved with the same absorbed pump power in a passively Q-switched Nd:YVO4 microchip laser under linearly polarized pumping when the incident pump power and the crystalline orientation of an a-cut Nd:YVO4 crystal are both properly selected. The significant improvement of pulsed laser performance of controllable IG modes has been achieved by selecting the crystalline orientation of an a-cut Nd:YVO4 crystal. The maximum pulse energy is obtained along the a-axis of an a-cut Nd:YVO4 crystal and the highest peak power is achieved along the c-axis of an a-cut Nd:YVO4 crystal, respectively, which has potential applications on quantum computation and optical manipulation. The generation of controllable IG laser modes in microchip lasers under linearly polarized pumping provides a convenient and universal way to control IG laser mode numbers with anisotropic crystal as a gain medium.
Sadeh, Sadra; Rotter, Stefan
2015-01-01
The neuronal mechanisms underlying the emergence of orientation selectivity in the primary visual cortex of mammals are still elusive. In rodents, visual neurons show highly selective responses to oriented stimuli, but neighboring neurons do not necessarily have similar preferences. Instead of a smooth map, one observes a salt-and-pepper organization of orientation selectivity. Modeling studies have recently confirmed that balanced random networks are indeed capable of amplifying weakly tuned inputs and generating highly selective output responses, even in absence of feature-selective recurrent connectivity. Here we seek to elucidate the neuronal mechanisms underlying this phenomenon by resorting to networks of integrate-and-fire neurons, which are amenable to analytic treatment. Specifically, in networks of perfect integrate-and-fire neurons, we observe that highly selective and contrast invariant output responses emerge, very similar to networks of leaky integrate-and-fire neurons. We then demonstrate that a theory based on mean firing rates and the detailed network topology predicts the output responses, and explains the mechanisms underlying the suppression of the common-mode, amplification of modulation, and contrast invariance. Increasing inhibition dominance in our networks makes the rectifying nonlinearity more prominent, which in turn adds some distortions to the otherwise essentially linear prediction. An extension of the linear theory can account for all the distortions, enabling us to compute the exact shape of every individual tuning curve in our networks. We show that this simple form of nonlinearity adds two important properties to orientation selectivity in the network, namely sharpening of tuning curves and extra suppression of the modulation. The theory can be further extended to account for the nonlinearity of the leaky model by replacing the rectifier by the appropriate smooth input-output transfer function. These results are robust and do not depend on the state of network dynamics, and hold equally well for mean-driven and fluctuation-driven regimes of activity.
Sadeh, Sadra; Rotter, Stefan
2015-01-01
The neuronal mechanisms underlying the emergence of orientation selectivity in the primary visual cortex of mammals are still elusive. In rodents, visual neurons show highly selective responses to oriented stimuli, but neighboring neurons do not necessarily have similar preferences. Instead of a smooth map, one observes a salt-and-pepper organization of orientation selectivity. Modeling studies have recently confirmed that balanced random networks are indeed capable of amplifying weakly tuned inputs and generating highly selective output responses, even in absence of feature-selective recurrent connectivity. Here we seek to elucidate the neuronal mechanisms underlying this phenomenon by resorting to networks of integrate-and-fire neurons, which are amenable to analytic treatment. Specifically, in networks of perfect integrate-and-fire neurons, we observe that highly selective and contrast invariant output responses emerge, very similar to networks of leaky integrate-and-fire neurons. We then demonstrate that a theory based on mean firing rates and the detailed network topology predicts the output responses, and explains the mechanisms underlying the suppression of the common-mode, amplification of modulation, and contrast invariance. Increasing inhibition dominance in our networks makes the rectifying nonlinearity more prominent, which in turn adds some distortions to the otherwise essentially linear prediction. An extension of the linear theory can account for all the distortions, enabling us to compute the exact shape of every individual tuning curve in our networks. We show that this simple form of nonlinearity adds two important properties to orientation selectivity in the network, namely sharpening of tuning curves and extra suppression of the modulation. The theory can be further extended to account for the nonlinearity of the leaky model by replacing the rectifier by the appropriate smooth input-output transfer function. These results are robust and do not depend on the state of network dynamics, and hold equally well for mean-driven and fluctuation-driven regimes of activity. PMID:25569445
Marno, Hanna; Farroni, Teresa; Vidal Dos Santos, Yamil; Ekramnia, Milad; Nespor, Marina; Mehler, Jacques
2015-01-01
Infants’ sensitivity to selectively attend to human speech and to process it in a unique way has been widely reported in the past. However, in order to successfully acquire language, one should also understand that speech is a referential, and that words can stand for other entities in the world. While there has been some evidence showing that young infants can make inferences about the communicative intentions of a speaker, whether they would also appreciate the direct relationship between a specific word and its referent, is still unknown. In the present study we tested four-month-old infants to see whether they would expect to find a referent when they hear human speech. Our results showed that compared to other auditory stimuli or to silence, when infants were listening to speech they were more prepared to find some visual referents of the words, as signalled by their faster orienting towards the visual objects. Hence, our study is the first to report evidence that infants at a very young age already understand the referential relationship between auditory words and physical objects, thus show a precursor in appreciating the symbolic nature of language, even if they do not understand yet the meanings of words. PMID:26323990
ERIC Educational Resources Information Center
Edward, Norrie; Middleton, June
2002-01-01
First-year engineering students at Robert Gordon University (Scotland) were presented with a task-oriented induction program. Students were divided into groups and assigned a facilitator, later personal tutor, to whom they could refer. Student reaction to the experience was very favorable. Effect on progression rates is yet to be determined. (AEF)
ERIC Educational Resources Information Center
Clark, John L.; And Others
This document sets out a "Framework" to underpin the development and ongoing renewal of the school curriculum in Hong Kong. It also indicates the bases on which the Framework is developed. The Framework forms the foundation of Hong Kong's Target-Oriented Curriculum (TOC) initiative and provides a useful reference for curriculum…
ERIC Educational Resources Information Center
Carter, Rona; Silverman, Wendy K.; Jaccard, James
2011-01-01
This study evaluated whether pubertal development and gender role orientation (i.e., masculinity and femininity) can partially explain sex variations in youth anxiety symptoms among clinic-referred anxious youth (N = 175; ages 9-13 years; 74% Hispanic; 48% female). Using youth and parent ratings of youth anxiety symptoms, structural equation…
ERIC Educational Resources Information Center
Yadavaia, James E.; Hayes, Steven C.
2012-01-01
This study evaluated the effectiveness of 6 to 10 sessions of Acceptance and Commitment Therapy (ACT) for self-stigma around sexual orientation linked to same-sex attraction (what has generally been referred to as internalized homophobia; IH) in a concurrent multiple-baseline across-participants design. Three men and 2 women showed sizeable…
ERIC Educational Resources Information Center
Foa, Chiara; Brugman, Daniel; Mancini, Tiziana
2012-01-01
The school moral atmosphere refers to informal norms and values that regulate the relationships in school and their degree of sharing among students. We tested whether the school moral atmosphere is a mediating variable between adolescents' normative orientation and their self-reported aggressive and transgressive behaviours. A total of 664…
Keystone Life Orientation (LO) Teachers: Implications for Educational, Social, and Cultural Contexts
ERIC Educational Resources Information Center
Pillay, Jace
2012-01-01
The aim of this study was to identify and describe skills, characteristics and support networks needed by keystone Life Orientation (LO) teachers in six Gauteng schools. In this study "keystone" refers to LO teachers who make a positive impact in their schools. A qualitative research design was used to collect data through interviews,…
NASA Astrophysics Data System (ADS)
Koroloff, Sophie N.; Nevzorov, Alexander A.
2017-01-01
Spectroscopic assignment of NMR spectra for oriented uniformly labeled membrane proteins embedded in their native-like bilayer environment is essential for their structure determination. However, sequence-specific assignment in oriented-sample (OS) NMR is often complicated by insufficient resolution and spectral crowding. Therefore, the assignment process is usually done by a laborious and expensive "shotgun" method involving multiple selective labeling of amino acid residues. Presented here is a strategy to overcome poor spectral resolution in crowded regions of 2D spectra by selecting resolved "seed" residues via soft Gaussian pulses inserted into spin-exchange separated local-field experiments. The Gaussian pulse places the selected polarization along the z-axis while dephasing the other signals before the evolution of the 1H-15N dipolar couplings. The transfer of magnetization is accomplished via mismatched Hartmann-Hahn conditions to the nearest-neighbor peaks via the proton bath. By optimizing the length and amplitude of the Gaussian pulse, one can also achieve a phase inversion of the closest peaks, thus providing an additional phase contrast. From the superposition of the selective spin-exchanged SAMPI4 onto the fully excited SAMPI4 spectrum, the 15N sites that are directly adjacent to the selectively excited residues can be easily identified, thereby providing a straightforward method for initiating the assignment process in oriented membrane proteins.
Use of an Orientation Clinic to Reduce Failed New Patient Appointments in Primary Care
Jain, Sharad; Chou, Calvin L
2000-01-01
Patients who fail to attend initial appointments reduce clinic efficiency. To maximize attendance by newly referred outpatients, we introduced a mandatory group orientation clinic for all new patients and determined its effects on no-show rates. Orientation clinic also provided health care screening and opportunities for patient feedback. The new patient no-show rate for initial provider visits decreased significantly from 45% before institution of orientation clinic to 18% afterwards (P < .0001). The total no-show (patients who failed to attend orientation clinic or an initial provider visit) rate of the postintervention group was 51% (P = .28, compared with before the intervention). This intervention improved the efficiency and minimized the wasted time of our clinicians. PMID:11119184
Atom probe field ion microscopy and related topics: A bibliography 1993
DOE Office of Scientific and Technical Information (OSTI.GOV)
Godfrey, R.D.; Miller, M.K.; Russell, K.F.
1994-10-01
This bibliography, covering the period 1993, includes references related to the following topics: atom probe field ion microscopy (APFIM), field emission (FE), and field ion microscopy (FIM). Technique-oriented studies and applications are included. The references contained in this document were compiled from a variety of sources including computer searches and personal lists of publications. To reduce the length of this document, the references have been reduced to the minimum necessary to locate the articles. The references are listed alphabetically by authors, an Addendum of references missed in previous bibliographies is included.
ERIC Educational Resources Information Center
Kornilova, Tatiana V.; Kornilov, Sergey A.; Chumakova, Maria A.
2009-01-01
The study examined the relationship between implicit theories, goal orientations, subjective and test estimates of intelligence, academic self-concept, and achievement in a selective student population (N=300). There was no direct impact of implicit theories of intelligence and goal orientations on achievement. However, subjective evaluations of…
ERIC Educational Resources Information Center
Mak, Kendrew K. W.; Lai, Y. M.; Siu, Yuk-Hong
2006-01-01
This article describes a discovery-oriented experiment for demonstrating the selectivity of two epoxidation reactions. Peroxy acids and alkaline H[subscript 2]O[subscript 2] are two commonly used reagents for alkene epoxidation. The former react preferentially with electron-rich alkenes while the latter works better with alpha,beta-unsaturated…
Morphology and Orientation Selection of Non-metallic Inclusions in Electrified Molten Metal
NASA Astrophysics Data System (ADS)
Zhao, Z. C.; Qin, R. S.
2017-10-01
The effect of electric current on morphology and orientation selection of non-metallic inclusions in molten metal has been investigated using theoretical modeling and numerical calculation. Two geometric factors, namely the circularity ( fc ) and alignment ratio ( fe ) were introduced to describe the inclusions shape and configuration. Electric current free energy was calculated and the values were used to determine the thermodynamic preference between different microstructures. Electric current promotes the development of inclusion along the current direction by either expatiating directional growth or enhancing directional agglomeration. Reconfiguration of the inclusions to reduce the system electric resistance drives the phenomena. The morphology and orientation selection follow the routine to reduce electric free energy. The numerical results are in agreement with our experimental observations.
Transhomosexuality, or the dissociation of sexual orientation and sex object choice.
Clare, D; Tully, B
1989-12-01
Subjects whose sexual orientation and identification is with homosexual persons of the opposite biological sex were studied. "Transhomosexual" has been coined to describe such persons. Forms of transhomosexual expression vary with different emphases found in regard to orientation to, idealization of, and wish to participate in activities of homosexuals of the opposite biological sex. Where identification is strong or overriding, such persons become "transsexual." However, there are important differences between these and conventionally diagnosed transsexuals. Sexual orientation then is not defined entirely or always by the sex of the sexual object choice, but sometimes additionally by references to preferred heterosexual or homosexual styles of relationship.
Representing object oriented specifications and designs with extended data flow notations
NASA Technical Reports Server (NTRS)
Buser, Jon Franklin; Ward, Paul T.
1988-01-01
The issue of using extended data flow notations to document object oriented designs and specifications is discussed. Extended data flow notations, for the purposes here, refer to notations that are based on the rules of Yourdon/DeMarco data flow analysis. The extensions include additional notation for representing real-time systems as well as some proposed extensions specific to object oriented development. Some advantages of data flow notations are stated. How data flow diagrams are used to represent software objects are investigated. Some problem areas with regard to using data flow notations for object oriented development are noted. Some initial solutions to these problems are proposed.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Escobedo, Fernando A., E-mail: fe13@cornell.edu
The phase behavior and the homogeneous nucleation of an equimolar mixture of octahedra and cuboctahedra are studied using thermodynamic integration, Gibbs-Duhem integration, and umbrella sampling simulations. The components of this mixture are modeled as polybead objects of equal edge lengths so that they can assemble into a space-filling compound with the CsCl crystal structure. Taking as reference the hard-core system where the compound crystal does not spontaneously nucleate, we quantified the effect of inter-species selective interactions on facilitating the disorder-to-order transition. Facet selective and facet non-selective inter-species attractions were considered, and while the former was expectedly more favorable toward themore » target tessellating structure, the latter was found to be similarly effective in nucleating the crystal compound. Ranges for the strength of attractions and degree of supersaturation were identified where the nucleation free-energy barrier was small enough to foretell a fast process but large enough to prevent spinodal fluctuations that can trap the system in dense metastable states lacking long-range order. At those favorable conditions, the tendency toward the local orientational order favored by packing entropy is amplified and found to play a key role seeding nuclei with the CsCl structure.« less
Achievement Goal Orientation for Athletic Training Education: Preparing for Lifelong Learning
ERIC Educational Resources Information Center
Peer, Kimberly S.
2007-01-01
Objective: This review of literature presents the theoretical framework of goal orientation and student achievement from a pedagogical perspective while providing practical applications and implications for integrating goal orientation into athletic training education programs. Data Sources: Selected literature derived from EBSCO, Education…
Markant, Julie; Ackerman, Laura K.; Nussenbaum, Kate; Amso, Dima
2015-01-01
Socioeconomic status (SES) has a documented impact on brain and cognitive development. We demonstrate that engaging spatial selective attention mechanisms may counteract this negative influence of impoverished environments on early learning. We previously used a spatial cueing task to compare target object encoding in the context of basic orienting (“facilitation”) versus a spatial selective attention orienting mechanism that engages distractor suppression (“IOR”). This work showed that object encoding in the context of IOR boosted 9-month-old infants’ recognition memory relative to facilitation (Markant and Amso, 2013). Here we asked whether this attention-memory links further interacted with SES in infancy. Results indicated that SES was related to memory but not attention orienting efficacy. However, the correlation between SES and memory performance was moderated by the attention mechanism engaged during encoding. SES predicted memory performance when objects were encoded with basic orienting processes, with infants from low-SES environments showing poorer memory than those from high-SES environments. However, SES did not predict memory performance among infants who engaged selective attention during encoding. Spatial selective attention engagement mitigated the effects of SES on memory and may offer an effective mechanism for promoting learning among infants at risk for poor cognitive outcomes related to SES. PMID:26597046
Gender differences associated with orienting attentional networks in healthy subjects.
Liu, Gang; Hu, Pan-Pan; Fan, Jin; Wang, Kai
2013-06-01
Selective attention is considered one of the main components of cognitive functioning. A number of studies have demonstrated gender differences in cognition. This study aimed to investigate the gender differences in selective attention in healthy subjects. The present experiment examined the gender differences associated with the efficiency of three attentional networks: alerting, orienting, and executive control attention in 73 healthy subjects (38 males). All participants performed a modified version of the Attention Network Test (ANT). Females had higher orienting scores than males (t = 2.172, P < 0.05). Specifically, females were faster at covert orienting of attention to a spatially cued location. There were no gender differences between males and females in alerting (t = 0.813, P > 0.05) and executive control (t = 0.945, P > 0.05) attention networks. There was a significant gender difference between males and females associated with the orienting network. Enhanced orienting attention in females may function to motivate females to direct their attention to a spatially cued location.
Supranormal orientation selectivity of visual neurons in orientation-restricted animals.
Sasaki, Kota S; Kimura, Rui; Ninomiya, Taihei; Tabuchi, Yuka; Tanaka, Hiroki; Fukui, Masayuki; Asada, Yusuke C; Arai, Toshiya; Inagaki, Mikio; Nakazono, Takayuki; Baba, Mika; Kato, Daisuke; Nishimoto, Shinji; Sanada, Takahisa M; Tani, Toshiki; Imamura, Kazuyuki; Tanaka, Shigeru; Ohzawa, Izumi
2015-11-16
Altered sensory experience in early life often leads to remarkable adaptations so that humans and animals can make the best use of the available information in a particular environment. By restricting visual input to a limited range of orientations in young animals, this investigation shows that stimulus selectivity, e.g., the sharpness of tuning of single neurons in the primary visual cortex, is modified to match a particular environment. Specifically, neurons tuned to an experienced orientation in orientation-restricted animals show sharper orientation tuning than neurons in normal animals, whereas the opposite was true for neurons tuned to non-experienced orientations. This sharpened tuning appears to be due to elongated receptive fields. Our results demonstrate that restricted sensory experiences can sculpt the supranormal functions of single neurons tailored for a particular environment. The above findings, in addition to the minimal population response to orientations close to the experienced one, agree with the predictions of a sparse coding hypothesis in which information is represented efficiently by a small number of activated neurons. This suggests that early brain areas adopt an efficient strategy for coding information even when animals are raised in a severely limited visual environment where sensory inputs have an unnatural statistical structure.
Supranormal orientation selectivity of visual neurons in orientation-restricted animals
Sasaki, Kota S.; Kimura, Rui; Ninomiya, Taihei; Tabuchi, Yuka; Tanaka, Hiroki; Fukui, Masayuki; Asada, Yusuke C.; Arai, Toshiya; Inagaki, Mikio; Nakazono, Takayuki; Baba, Mika; Kato, Daisuke; Nishimoto, Shinji; Sanada, Takahisa M.; Tani, Toshiki; Imamura, Kazuyuki; Tanaka, Shigeru; Ohzawa, Izumi
2015-01-01
Altered sensory experience in early life often leads to remarkable adaptations so that humans and animals can make the best use of the available information in a particular environment. By restricting visual input to a limited range of orientations in young animals, this investigation shows that stimulus selectivity, e.g., the sharpness of tuning of single neurons in the primary visual cortex, is modified to match a particular environment. Specifically, neurons tuned to an experienced orientation in orientation-restricted animals show sharper orientation tuning than neurons in normal animals, whereas the opposite was true for neurons tuned to non-experienced orientations. This sharpened tuning appears to be due to elongated receptive fields. Our results demonstrate that restricted sensory experiences can sculpt the supranormal functions of single neurons tailored for a particular environment. The above findings, in addition to the minimal population response to orientations close to the experienced one, agree with the predictions of a sparse coding hypothesis in which information is represented efficiently by a small number of activated neurons. This suggests that early brain areas adopt an efficient strategy for coding information even when animals are raised in a severely limited visual environment where sensory inputs have an unnatural statistical structure. PMID:26567927
The Egocentric Reference for Visual Exploration and Orientation
ERIC Educational Resources Information Center
Nico, Daniele; Daprati, Elena
2009-01-01
Clinical signs of damage to the egocentric reference system range from the inability to detect stimuli in the real environment to a defect in recovering items from an internal representation. Despite clinical dissociations, current interpretations consider all symptoms as due to a single perturbation, differentially expressed according to the…
Environmental Services (Bibliography), January 1973 (Revised).
ERIC Educational Resources Information Center
Hoduski, Bernadine E., Comp.
This bibliography of environmental services is designed for general orientation and not intended as a comprehensive listing. Reference is made only to information systems initiated by the Environmental Protection Agency (EPA) or those which contain reference to EPA services. The booklet is divided into three sections: (1) EPA information systems,…
The Interview as Collaborative Achievement: Interaction, Identity, and Ideology in a Speech Event
ERIC Educational Resources Information Center
Talmy, Steven
2011-01-01
This article contrasts a common conceptualization of the interview in applied linguistics, referred to as an "interview as research instrument" perspective, with an alternative, referred to as a "research interview as social practice" orientation. It illustrates implications of the two perspectives on interviews by contrasting…
Border Crossings and Multimodal Composition in the Arts
ERIC Educational Resources Information Center
Morrison, Andrew
2005-01-01
Developmental and development-oriented learning with digital media are discussed in relation to the concepts border crossings and multimodal composition. The first concept refers to a transveral of disciplines and recombinations of elements from them. Local-global relations in knowledge building are covered. The second refers to the collaborative…
Solav, Dana; Rubin, M B; Cereatti, Andrea; Camomilla, Valentina; Wolf, Alon
2016-04-01
Accurate estimation of the position and orientation (pose) of a bone from a cluster of skin markers is limited mostly by the relative motion between the bone and the markers, which is known as the soft tissue artifact (STA). This work presents a method, based on continuum mechanics, to describe the kinematics of a cluster affected by STA. The cluster is characterized by triangular cosserat point elements (TCPEs) defined by all combinations of three markers. The effects of the STA on the TCPEs are quantified using three parameters describing the strain in each TCPE and the relative rotation and translation between TCPEs. The method was evaluated using previously collected ex vivo kinematic data. Femur pose was estimated from 12 skin markers on the thigh, while its reference pose was measured using bone pins. Analysis revealed that instantaneous subsets of TCPEs exist which estimate bone position and orientation more accurately than the Procrustes Superimposition applied to the cluster of all markers. It has been shown that some of these parameters correlate well with femur pose errors, which suggests that they can be used to select, at each instant, subsets of TCPEs leading an improved estimation of the underlying bone pose.
A digital system for surface reconstruction
Zhou, Weiyang; Brock, Robert H.; Hopkins, Paul F.
1996-01-01
A digital photogrammetric system, STEREO, was developed to determine three dimensional coordinates of points of interest (POIs) defined with a grid on a textureless and smooth-surfaced specimen. Two CCD cameras were set up with unknown orientation and recorded digital images of a reference model and a specimen. Points on the model were selected as control or check points for calibrating or assessing the system. A new algorithm for edge-detection called local maximum convolution (LMC) helped extract the POIs from the stereo image pairs. The system then matched the extracted POIs and used a least squares “bundle” adjustment procedure to solve for the camera orientation parameters and the coordinates of the POIs. An experiment with STEREO found that the standard deviation of the residuals at the check points was approximately 24%, 49% and 56% of the pixel size in the X, Y and Z directions, respectively. The average of the absolute values of the residuals at the check points was approximately 19%, 36% and 49% of the pixel size in the X, Y and Z directions, respectively. With the graphical user interface, STEREO demonstrated a high degree of automation and its operation does not require special knowledge of photogrammetry, computers or image processing.
NASA Astrophysics Data System (ADS)
Chen, J.; Chen, W.; Dou, A.; Li, W.; Sun, Y.
2018-04-01
A new information extraction method of damaged buildings rooted in optimal feature space is put forward on the basis of the traditional object-oriented method. In this new method, ESP (estimate of scale parameter) tool is used to optimize the segmentation of image. Then the distance matrix and minimum separation distance of all kinds of surface features are calculated through sample selection to find the optimal feature space, which is finally applied to extract the image of damaged buildings after earthquake. The overall extraction accuracy reaches 83.1 %, the kappa coefficient 0.813. The new information extraction method greatly improves the extraction accuracy and efficiency, compared with the traditional object-oriented method, and owns a good promotional value in the information extraction of damaged buildings. In addition, the new method can be used for the information extraction of different-resolution images of damaged buildings after earthquake, then to seek the optimal observation scale of damaged buildings through accuracy evaluation. It is supposed that the optimal observation scale of damaged buildings is between 1 m and 1.2 m, which provides a reference for future information extraction of damaged buildings.
Hamm, J V
2000-03-01
Variability in adolescent-friend similarity is documented in a diverse sample of African American, Asian American, and European American adolescents. Similarity was greatest for substance use, modest for academic orientations, and low for ethnic identity. Compared with Asian American and European American adolescents, African American adolescents chose friends who were less similar with respect to academic orientation or substance use but more similar with respect to ethnic identity. For all three ethnic groups, personal endorsement of the dimension in question and selection of cross-ethnic-group friends heightened similarity. Similarity was a relative rather than an absolute selection criterion: Adolescents did not choose friends with identical orientations. These findings call for a comprehensive theory of friendship selection sensitive to diversity in adolescents' experiences. Implications for peer influence and self-development are discussed.
Why Johnny can't reengineer health care processes with information technology.
Webster, C; McLinden, S; Begler, K
1995-01-01
Many educational institutions are developing curricula that integrate computer and business knowledge and skills concerning a specific industry, such as banking or health care. We have developed a curriculum that emphasizes, equally, medical, computer, and business management concepts. Along the way we confronted a formidable obstacle, namely the domain specificity of the reference disciplines. Knowledge within each domain is sufficiently different from other domains that it reduces the leverage of building on preexisting knowledge and skills. We review this problem from the point of view of cognitive science (in particular, knowledge representation and machine learning) to suggest strategies for coping with incommensurate domain ontologies. These strategies include reflective judgment, implicit learning, abstraction, generalization, analogy, multiple inheritance, project-orientation, selectivity, goal- and failure-driven learning, and case- and story-based learning.
The Helicopter Antenna Radiation Prediction Code (HARP)
NASA Technical Reports Server (NTRS)
Klevenow, F. T.; Lynch, B. G.; Newman, E. H.; Rojas, R. G.; Scheick, J. T.; Shamansky, H. T.; Sze, K. Y.
1990-01-01
The first nine months effort in the development of a user oriented computer code, referred to as the HARP code, for analyzing the radiation from helicopter antennas is described. The HARP code uses modern computer graphics to aid in the description and display of the helicopter geometry. At low frequencies the helicopter is modeled by polygonal plates, and the method of moments is used to compute the desired patterns. At high frequencies the helicopter is modeled by a composite ellipsoid and flat plates, and computations are made using the geometrical theory of diffraction. The HARP code will provide a user friendly interface, employing modern computer graphics, to aid the user to describe the helicopter geometry, select the method of computation, construct the desired high or low frequency model, and display the results.
Dynamic visual attention: motion direction versus motion magnitude
NASA Astrophysics Data System (ADS)
Bur, A.; Wurtz, P.; Müri, R. M.; Hügli, H.
2008-02-01
Defined as an attentive process in the context of visual sequences, dynamic visual attention refers to the selection of the most informative parts of video sequence. This paper investigates the contribution of motion in dynamic visual attention, and specifically compares computer models designed with the motion component expressed either as the speed magnitude or as the speed vector. Several computer models, including static features (color, intensity and orientation) and motion features (magnitude and vector) are considered. Qualitative and quantitative evaluations are performed by comparing the computer model output with human saliency maps obtained experimentally from eye movement recordings. The model suitability is evaluated in various situations (synthetic and real sequences, acquired with fixed and moving camera perspective), showing advantages and inconveniences of each method as well as preferred domain of application.
The Map in Our Head Is Not Oriented North: Evidence from a Real-World Environment.
Brunyé, Tad T; Burte, Heather; Houck, Lindsay A; Taylor, Holly A
2015-01-01
Like most physical maps, recent research has suggested that cognitive maps of familiar environments may have a north-up orientation. We demonstrate that north orientation is not a necessary feature of cognitive maps and instead may arise due to coincidental alignment between cardinal directions and the built and natural environment. Experiment 1 demonstrated that pedestrians have difficulty pointing north while navigating a familiar real-world environment with roads, buildings, and green spaces oriented oblique to cardinal axes. Instead, north estimates tended to be parallel or perpendicular to roads. In Experiment 2, participants did not demonstrate privileged memory access when oriented toward north while making relative direction judgments. Instead, retrieval was fastest and most accurate when orientations were aligned with roads. In sum, cognitive maps are not always oriented north. Rather, in some real-world environments they can be oriented with respect to environment-specific features, serving as convenient reference systems for organizing and using spatial memory.
Genomic Model with Correlation Between Additive and Dominance Effects.
Xiang, Tao; Christensen, Ole Fredslund; Vitezica, Zulma Gladis; Legarra, Andres
2018-05-09
Dominance genetic effects are rarely included in pedigree-based genetic evaluation. With the availability of single nucleotide polymorphism markers and the development of genomic evaluation, estimates of dominance genetic effects have become feasible using genomic best linear unbiased prediction (GBLUP). Usually, studies involving additive and dominance genetic effects ignore possible relationships between them. It has been often suggested that the magnitude of functional additive and dominance effects at the quantitative trait loci are related, but there is no existing GBLUP-like approach accounting for such correlation. Wellmann and Bennewitz showed two ways of considering directional relationships between additive and dominance effects, which they estimated in a Bayesian framework. However, these relationships cannot be fitted at the level of individuals instead of loci in a mixed model and are not compatible with standard animal or plant breeding software. This comes from a fundamental ambiguity in assigning the reference allele at a given locus. We show that, if there has been selection, assigning the most frequent as the reference allele orients the correlation between functional additive and dominance effects. As a consequence, the most frequent reference allele is expected to have a positive value. We also demonstrate that selection creates negative covariance between genotypic additive and dominance genetic values. For parameter estimation, it is possible to use a combined additive and dominance relationship matrix computed from marker genotypes, and to use standard restricted maximum likelihood (REML) algorithms based on an equivalent model. Through a simulation study, we show that such correlations can easily be estimated by mixed model software and accuracy of prediction for genetic values is slightly improved if such correlations are used in GBLUP. However, a model assuming uncorrelated effects and fitting orthogonal breeding values and dominant deviations performed similarly for prediction. Copyright © 2018, Genetics.
Consistent realization of Celestial and Terrestrial Reference Frames
NASA Astrophysics Data System (ADS)
Kwak, Younghee; Bloßfeld, Mathis; Schmid, Ralf; Angermann, Detlef; Gerstl, Michael; Seitz, Manuela
2018-03-01
The Celestial Reference System (CRS) is currently realized only by Very Long Baseline Interferometry (VLBI) because it is the space geodetic technique that enables observations in that frame. In contrast, the Terrestrial Reference System (TRS) is realized by means of the combination of four space geodetic techniques: Global Navigation Satellite System (GNSS), VLBI, Satellite Laser Ranging (SLR), and Doppler Orbitography and Radiopositioning Integrated by Satellite. The Earth orientation parameters (EOP) are the link between the two types of systems, CRS and TRS. The EOP series of the International Earth Rotation and Reference Systems Service were combined of specifically selected series from various analysis centers. Other EOP series were generated by a simultaneous estimation together with the TRF while the CRF was fixed. Those computation approaches entail inherent inconsistencies between TRF, EOP, and CRF, also because the input data sets are different. A combined normal equation (NEQ) system, which consists of all the parameters, i.e., TRF, EOP, and CRF, would overcome such an inconsistency. In this paper, we simultaneously estimate TRF, EOP, and CRF from an inter-technique combined NEQ using the latest GNSS, VLBI, and SLR data (2005-2015). The results show that the selection of local ties is most critical to the TRF. The combination of pole coordinates is beneficial for the CRF, whereas the combination of Δ UT1 results in clear rotations of the estimated CRF. However, the standard deviations of the EOP and the CRF improve by the inter-technique combination which indicates the benefits of a common estimation of all parameters. It became evident that the common determination of TRF, EOP, and CRF systematically influences future ICRF computations at the level of several μas. Moreover, the CRF is influenced by up to 50 μas if the station coordinates and EOP are dominated by the satellite techniques.
NASA Technical Reports Server (NTRS)
Abbott, Terence S.; Nataupsky, Mark; Steinmetz, George G.
1987-01-01
A ground-based aircraft simulation study was conducted to determine the effects on pilot preference and performance of integrating airspeed and altitude information into an advanced electronic primary flight display via moving-tape (linear moving scale) formats. Several key issues relating to the implementation of moving-tape formats were examined in this study: tape centering, tape orientation, and trend information. The factor of centering refers to whether the tape was centered about the actual airspeed or altitude or about some other defined reference value. Tape orientation refers to whether the represented values are arranged in descending or ascending order. Two pilots participated in this study, with each performing 32 runs along seemingly random, previously unknown flight profiles. The data taken, analyzed, and presented consisted of path performance parameters, pilot-control inputs, and electrical brain response measurements.
He, Xingrong; Yang, Yongqiang; Wu, Weihui; Wang, Di; Ding, Huanwen; Huang, Weihong
2010-06-01
In order to simplify the distal femoral comminuted fracture surgery and improve the accuracy of the parts to be reset, a kind of surgery orienting model for the surgery operation was designed according to the scanning data of computer tomography and the three-dimensional reconstruction image. With the use of DiMetal-280 selective laser melting rapid prototyping system, the surgery orienting model of 316L stainless steel was made through orthogonal experiment for processing parameter optimization. The technology of direct manufacturing of surgery orienting model by selective laser melting was noted to have obvious superiority with high speed, precise profile and good accuracy in size when compared with the conventional one. The model was applied in a real surgical operation for thighbone replacement; it worked well. The successful development of the model provides a new method for the automatic manufacture of customized surgery model, thus building a foundation for more clinical applications in the future.
Gender variance in childhood and sexual orientation in adulthood: a prospective study.
Steensma, Thomas D; van der Ende, Jan; Verhulst, Frank C; Cohen-Kettenis, Peggy T
2013-11-01
Several retrospective and prospective studies have reported on the association between childhood gender variance and sexual orientation and gender discomfort in adulthood. In most of the retrospective studies, samples were drawn from the general population. The samples in the prospective studies consisted of clinically referred children. In understanding the extent to which the association applies for the general population, prospective studies using random samples are needed. This prospective study examined the association between childhood gender variance, and sexual orientation and gender discomfort in adulthood in the general population. In 1983, we measured childhood gender variance, in 406 boys and 473 girls. In 2007, sexual orientation and gender discomfort were assessed. Childhood gender variance was measured with two items from the Child Behavior Checklist/4-18. Sexual orientation was measured for four parameters of sexual orientation (attraction, fantasy, behavior, and identity). Gender discomfort was assessed by four questions (unhappiness and/or uncertainty about one's gender, wish or desire to be of the other gender, and consideration of living in the role of the other gender). For both men and women, the presence of childhood gender variance was associated with homosexuality for all four parameters of sexual orientation, but not with bisexuality. The report of adulthood homosexuality was 8 to 15 times higher for participants with a history of gender variance (10.2% to 12.2%), compared to participants without a history of gender variance (1.2% to 1.7%). The presence of childhood gender variance was not significantly associated with gender discomfort in adulthood. This study clearly showed a significant association between childhood gender variance and a homosexual sexual orientation in adulthood in the general population. In contrast to the findings in clinically referred gender-variant children, the presence of a homosexual sexual orientation in adulthood was substantially lower. © 2012 International Society for Sexual Medicine.
NASA Astrophysics Data System (ADS)
Yang, Ruijie; Dai, Jianrong; Yang, Yong; Hu, Yimin
2006-08-01
The purpose of this study is to extend an algorithm proposed for beam orientation optimization in classical conformal radiotherapy to intensity-modulated radiation therapy (IMRT) and to evaluate the algorithm's performance in IMRT scenarios. In addition, the effect of the candidate pool of beam orientations, in terms of beam orientation resolution and starting orientation, on the optimized beam configuration, plan quality and optimization time is also explored. The algorithm is based on the technique of mixed integer linear programming in which binary and positive float variables are employed to represent candidates for beam orientation and beamlet weights in beam intensity maps. Both beam orientations and beam intensity maps are simultaneously optimized in the algorithm with a deterministic method. Several different clinical cases were used to test the algorithm and the results show that both target coverage and critical structures sparing were significantly improved for the plans with optimized beam orientations compared to those with equi-spaced beam orientations. The calculation time was less than an hour for the cases with 36 binary variables on a PC with a Pentium IV 2.66 GHz processor. It is also found that decreasing beam orientation resolution to 10° greatly reduced the size of the candidate pool of beam orientations without significant influence on the optimized beam configuration and plan quality, while selecting different starting orientations had large influence. Our study demonstrates that the algorithm can be applied to IMRT scenarios, and better beam orientation configurations can be obtained using this algorithm. Furthermore, the optimization efficiency can be greatly increased through proper selection of beam orientation resolution and starting beam orientation while guaranteeing the optimized beam configurations and plan quality.
Aesthetic judgement of orientation in modern art.
Mather, George
2012-01-01
When creating an artwork, the artist makes a decision regarding the orientation at which the work is to be hung based on their aesthetic judgement and the message conveyed by the piece. Is the impact or aesthetic appeal of a work diminished when it is hung at an incorrect orientation? To investigate this question, Experiment 1 asked whether naïve observers can appreciate the correct orientation (as defined by the artist) of 40 modern artworks, some of which are entirely abstract. Eighteen participants were shown 40 paintings in a series of trials. Each trial presented all four cardinal orientations on a computer screen, and the participant was asked to select the orientation that was most attractive or meaningful. Results showed that the correct orientation was selected in 48% of trials on average, significantly above the 25% chance level, but well below perfect performance. A second experiment investigated the extent to which the 40 paintings contained recognisable content, which may have mediated orientation judgements. Recognition rates varied from 0% for seven of the paintings to 100% for five paintings. Orientation judgements in Experiment 1 correlated significantly with "meaningful" content judgements in Experiment 2: 42% of the variance in orientation judgements in Experiment 1 was shared with recognition of meaningful content in Experiment 2. For the seven paintings in which no meaningful content at all was detected, 41% of the variance in orientation judgements was shared with variance in a physical measure of image content, Fourier amplitude spectrum slope. For some paintings, orientation judgements were quite consistent, despite a lack of meaningful content. The origin of these orientation judgements remains to be identified.
CSAR-web: a web server of contig scaffolding using algebraic rearrangements.
Chen, Kun-Tze; Lu, Chin Lung
2018-05-04
CSAR-web is a web-based tool that allows the users to efficiently and accurately scaffold (i.e. order and orient) the contigs of a target draft genome based on a complete or incomplete reference genome from a related organism. It takes as input a target genome in multi-FASTA format and a reference genome in FASTA or multi-FASTA format, depending on whether the reference genome is complete or incomplete, respectively. In addition, it requires the users to choose either 'NUCmer on nucleotides' or 'PROmer on translated amino acids' for CSAR-web to identify conserved genomic markers (i.e. matched sequence regions) between the target and reference genomes, which are used by the rearrangement-based scaffolding algorithm in CSAR-web to order and orient the contigs of the target genome based on the reference genome. In the output page, CSAR-web displays its scaffolding result in a graphical mode (i.e. scalable dotplot) allowing the users to visually validate the correctness of scaffolded contigs and in a tabular mode allowing the users to view the details of scaffolds. CSAR-web is available online at http://genome.cs.nthu.edu.tw/CSAR-web.
ERIC Educational Resources Information Center
Longo, Paul J.
This study explored the mechanics of using an enhanced, comprehensive multipurpose logic model, the Performance Blueprint, as a means of building evaluation capacity, referred to in this paper as performance measurement literacy, to facilitate the attainment of both service-delivery oriented and community-oriented outcomes. The application of this…
The Moral Reasoning of Adolescent Boys and Girls in the Light of Gilligan's Theory
ERIC Educational Resources Information Center
Kalsoom, Farhat; Behlol, Malik Ghulam; Kayani, Muhammad Munir; Kaini, Aneesa
2012-01-01
The study was conducted to assess the moral reasoning of adolescent boys and girls in the light of Gilligan theory. The main objectives of the study were to investigate the moral reasoning of adolescent boys and girls with reference to responsibility orientation versus justice orientation and to compare the frequency of adolescent boys and girls…
ERIC Educational Resources Information Center
Leondari, Angeliki; Gonida, Eleftheria
2007-01-01
Background: Academic self-handicapping refers to the use of impediments to successful performance on academic tasks. Previous studies have shown that it is related to personal achievement goals. A performance goal orientation is a positive predictor of self-handicapping, whereas a task goal orientation is unrelated to self-handicapping. Aims: The…
Gravitational Effects on Brain and Behavior
NASA Technical Reports Server (NTRS)
Young, Laurence R.
1991-01-01
Visual, vestibular, tactile, proprioceptive, and perhaps auditory clues are combined with knowledge of commanded voluntary movement to produce a single, usually consistent, perception of spatial orientation. The recent Spacelab flights have provided especially valuable observations on the effects of weightlessness and space flight. The response of the otolith organs to weightlessness and readapting to Earth's gravitation is described. Reference frames for orientation are briefly discussed.
Specificity of V1-V2 Orientation Networks in the Primate Visual Cortex
Roe, Anna W.; Ts'o, Daniel Y.
2015-01-01
The computation of texture and shape involves integration of features of various orientations. Orientation networks within V1 tend to involve cells which share similar orientation selectivity. However, emergent properties in V2 require the integration of multiple orientations. We now show that, unlike interactions within V1, V1-V2 orientation interactions are much less synchronized and are not necessarily orientation dependent. We find V1-V2 orientation networks are of two types: a more tightly synchronized, orientation-preserving network and a less synchronized orientation-diverse network. We suggest that such diversity of V1-V2 interactions underlies the spatial and functional integration required for computation of higher order contour and shape in V2. PMID:26314798
Nesting in an Object Oriented Language is NOT for the Birds
NASA Astrophysics Data System (ADS)
Buhr, P. A.; Zarnke, C. R.
The notion of nested blocks has come into disfavour or has been ignored in recent program language design. Many of the current object oriented programming languages use subclassing as the sole mechanism to establish relationships between classes and have no general notion of nesting. We argue that nesting (and, more generally, hierarchical organization) is a powerful mechanism that provides facilities that are not otherwise possible in a class based programming language. We agree that traditional block structure and its associated nesting have severe problems, and we suggest several extensions to the notion of blocks and block structure that indirectly make nesting a useful and powerful mechanism, particularly in an object oriented programming system. The main extension is to allow references to definitions from outside of the containing block, thereby making the contained definitions available in a larger scope. References are made using either the name of the containing entity or an instance of the containing entity. The extensions suggest a way to organize the programming environment for a large, multi-user system. These facilities are not available with subclassing, and subclassing provides facilities not available by nesting; hence, an object oriented language can benefit by providing nesting as well.
1990-10-01
to economic, technological, spatial or logistic concerns, or involve training, man-machine interfaces, or integration into existing systems. Once the...probabilistic reasoning, mixed analysis- and simulation-oriented, mixed computation- and communication-oriented, nonpreemptive static priority...scheduling base, nonrandomized, preemptive static priority scheduling base, randomized, simulation-oriented, and static scheduling base. The selection of both
Film as a Lens for Teaching Culture: Balancing Concepts, Ambiguity, and Paradox.
ERIC Educational Resources Information Center
Mallinger, Mark; Rossy, Gerard
2003-01-01
Discusses how to apply dimensions of an integrated cultural framework (ability to influence, comfort with ambiguity, achievement orientation, individualism/collectivism, time orientation, space orientation) to analysis of films as part of the study of culture. Gives an application example and selection guidelines and discusses limitations. (SK)
A Person-Oriented Approach: Methods for Today and Methods for Tomorrow
ERIC Educational Resources Information Center
Bergman, Lars R.; El-Khouri, Bassam M.
2003-01-01
Methodological implications of a person-oriented, holistic-interactionistic perspective in research on individual development are outlined, desirable properties of a mathematical model of a phenomenon are discussed, and selected methods for carrying out person-oriented research are briefly overviewed. These methods are: (1) the classificatory…
ERIC Educational Resources Information Center
Williamson, Ian O.; Lepak, David P.; King, James
2003-01-01
To obtain information on job opportunities, business students (n=252) visited company websites having either a recruitment or selection orientation or both. Attractiveness of the organization was significantly higher for recruitment-oriented sites. Perceived usefulness and ease of use influenced outcome expectancy and organizational…
What’s New? Children Prefer Novelty in Referent Selection
Horst, Jessica S.; Samuelson, Larissa K.; Kucker, Sarah C.; McMurray, Bob
2010-01-01
Determining the referent of a novel name is a critical task for young language learners. The majority of studies on children’s referent selection focus on manipulating the sources of information (linguistic, contextual and pragmatic) that children can use to solve the referent mapping problem. Here, we take a step back and explore how children’s endogenous biases towards novelty and their own familiarity with novel objects influence their performance in such a task. We familiarized 2-year-old children with previously novel objects. Then, on novel name referent selection trials children were asked to select the referent from three novel objects: two previously seen and one completely novel object. Children demonstrated a clear bias to select the most novel object. A second experiment controls for pragmatic responding and replicates this finding. We conclude, therefore, that children’s referent selection is biased by previous exposure and children’s endogenous bias to novelty. PMID:21092945
Child-oriented marketing techniques in snack food packages in Guatemala.
Chacon, Violeta; Letona, Paola; Barnoya, Joaquin
2013-10-18
Childhood overweight in Guatemala is now becoming a public health concern. Child-oriented marketing contributes to increase children's food preference, purchase and consumption. This study sought to assess the availability of child-oriented snack foods sold in school kiosks and convenience stores near public schools in Guatemala, to identify the marketing techniques used in child-oriented snack food packages and to classify the snacks as "healthy" or "less-healthy". We purchased all child-oriented snacks found in stores inside and within 200 square meters from four schools in an urban community. Snacks were classified as child-oriented if the package had any promotional characters, premium offers, children's television/movie tie-ins, sports references, or the word "child". We used a checklist to assess child-oriented references and price. Snacks were classified as "healthy" or "less-healthy" according to the UK standards for the Nutritional Profiling Model. We analyzed 106 packages found in 55 stores. The most commonly used technique was promotional characters (92.5%) of which 32.7% were brand-specific characters. Premium offers were found in 34% of packages and were mostly collectibles (50%). Most marketing techniques were located on the front and covered nearly 25% of the package surface. Median (interquartile range) price was US$ 0.19 (0.25). Nutrition labels were found in 91 (86%) packages and 41% had a nutrition related health claim. Most snacks (97.1%) were classified as "less-healthy". In Guatemala, the food industry targets children through several marketing techniques promoting inexpensive and unhealthy snacks in the school environment. Evidence-based policies restricting the use of promotional characters in unhealthy snack food packages need to be explored as a contributing strategy to control the obesity epidemic.
NASA Technical Reports Server (NTRS)
Wood, S. J.; Paloski, W. H.; Reschke, M. F.
1998-01-01
This purpose of this study was to examine the spatial coding of eye movements during static roll tilt (up to +/-45 degrees) relative to perceived earth and head orientations. Binocular videographic recordings obtained in darkness from eight subjects allowed us to quantify the mean deviations in gaze trajectories along both horizontal and vertical coordinates relative to the true earth and head orientations. We found that both variability and curvature of gaze trajectories increased with roll tilt. The trajectories of eye movements made along the perceived earth-horizontal (PEH) were more accurate than movements along the perceived head-horizontal (PHH). The trajectories of both PEH and PHH saccades tended to deviate in the same direction as the head tilt. The deviations in gaze trajectories along the perceived earth-vertical (PEV) and perceived head-vertical (PHV) were both similar to the PHH orientation, except that saccades along the PEV deviated in the opposite direction relative to the head tilt. The magnitude of deviations along the PEV, PHH, and PHV corresponded to perceptual overestimations of roll tilt obtained from verbal reports. Both PEV gaze trajectories and perceptual estimates of tilt orientation were different following clockwise rather than counterclockwise tilt rotation; however, the PEH gaze trajectories were less affected by the direction of tilt rotation. Our results suggest that errors in gaze trajectories along PEV and perceived head orientations increase during roll tilt in a similar way to perceptual errors of tilt orientation. Although PEH and PEV gaze trajectories became nonorthogonal during roll tilt, we conclude that the spatial coding of eye movements during roll tilt is overall more accurate for the perceived earth reference frame than for the perceived head reference frame.
Child-oriented marketing techniques in snack food packages in Guatemala
2013-01-01
Background Childhood overweight in Guatemala is now becoming a public health concern. Child-oriented marketing contributes to increase children’s food preference, purchase and consumption. This study sought to assess the availability of child-oriented snack foods sold in school kiosks and convenience stores near public schools in Guatemala, to identify the marketing techniques used in child-oriented snack food packages and to classify the snacks as “healthy” or “less-healthy”. Methods We purchased all child-oriented snacks found in stores inside and within 200 square meters from four schools in an urban community. Snacks were classified as child-oriented if the package had any promotional characters, premium offers, children′s television/movie tie-ins, sports references, or the word “child”. We used a checklist to assess child-oriented references and price. Snacks were classified as “healthy” or “less-healthy” according to the UK standards for the Nutritional Profiling Model. Results We analyzed 106 packages found in 55 stores. The most commonly used technique was promotional characters (92.5%) of which 32.7% were brand-specific characters. Premium offers were found in 34% of packages and were mostly collectibles (50%). Most marketing techniques were located on the front and covered nearly 25% of the package surface. Median (interquartile range) price was US$ 0.19 (0.25). Nutrition labels were found in 91 (86%) packages and 41% had a nutrition related health claim. Most snacks (97.1%) were classified as “less-healthy”. Conclusion In Guatemala, the food industry targets children through several marketing techniques promoting inexpensive and unhealthy snacks in the school environment. Evidence-based policies restricting the use of promotional characters in unhealthy snack food packages need to be explored as a contributing strategy to control the obesity epidemic. PMID:24139325
Tutorial: Crystal orientations and EBSD — Or which way is up?
DOE Office of Scientific and Technical Information (OSTI.GOV)
Britton, T.B., E-mail: b.britton@imperial.ac.uk; Jiang, J.; Guo, Y.
2016-07-15
Electron backscatter diffraction (EBSD) is an automated technique that can measure the orientation of crystals in a sample very rapidly. There are many sophisticated software packages that present measured data. Unfortunately, due to crystal symmetry and differences in the set-up of microscope and EBSD software, there may be accuracy issues when linking the crystal orientation to a particular microstructural feature. In this paper we outline a series of conventions used to describe crystal orientations and coordinate systems. These conventions have been used to successfully demonstrate that a consistent frame of reference is used in the sample, unit cell, pole figuremore » and diffraction pattern frames of reference. We establish a coordinate system rooted in measurement of the diffraction pattern and subsequently link this to all other coordinate systems. A fundamental outcome of this analysis is to note that the beamshift coordinate system needs to be precisely defined for consistent 3D microstructure analysis. This is supported through a series of case studies examining particular features of the microscope settings and/or unambiguous crystallographic features. These case studies can be generated easily in most laboratories and represent an opportunity to demonstrate confidence in use of recorded orientation data. Finally, we include a simple software tool, written in both MATLAB® and Python, which the reader can use to compare consistency with their own microscope set-up and which may act as a springboard for further offline analysis. - Highlights: • Presentation of conventions used to describe crystal orientations • Three case studies that outline how conventions are consistent • Demonstrates a pathway for calibration and validation of EBSD based orientation measurements • EBSD computer code supplied for validation by the reader.« less
Retrieving Enduring Spatial Representations after Disorientation
Li, Xiaoou; Mou, Weimin; McNamara, Timothy P.
2012-01-01
Four experiments tested whether there are enduring spatial representations of objects’ locations in memory. Previous studies have shown that under certain conditions the internal consistency of pointing to objects using memory is disrupted by disorientation. This disorientation effect has been attributed to an absence of or to imprecise enduring spatial representations of objects’ locations. Experiment 1 replicated the standard disorientation effect. Participants learned locations of objects in an irregular layout and then pointed to objects after physically turning to face an object and after disorientation. The expected disorientation was observed. In Experiment 2, after disorientation, participants were asked to imagine they were facing the original learning direction and then physically turned to adopt the test orientation. In Experiment 3, after disorientation, participants turned to adopt the test orientation and then were informed of the original viewing direction by the experimenter. A disorientation effect was not observed in Experiment 2 or 3. In Experiment 4, after disorientation, participants turned to face the test orientation but were not told the original learning orientation. As in Experiment 1, a disorientation effect was observed. These results suggest that there are enduring spatial representations of objects’ locations specified in terms of a spatial reference direction parallel to the learning view, and that the disorientation effect is caused by uncertainty in recovering the spatial reference direction relative to the testing orientation following disorientation. PMID:22682765
Ramírez, Fernando M
2018-05-01
Viewpoint-invariant face recognition is thought to be subserved by a distributed network of occipitotemporal face-selective areas that, except for the human anterior temporal lobe, have been shown to also contain face-orientation information. This review begins by highlighting the importance of bilateral symmetry for viewpoint-invariant recognition and face-orientation perception. Then, monkey electrophysiological evidence is surveyed describing key tuning properties of face-selective neurons-including neurons bimodally tuned to mirror-symmetric face-views-followed by studies combining functional magnetic resonance imaging (fMRI) and multivariate pattern analyses to probe the representation of face-orientation and identity information in humans. Altogether, neuroimaging studies suggest that face-identity is gradually disentangled from face-orientation information along the ventral visual processing stream. The evidence seems to diverge, however, regarding the prevalent form of tuning of neural populations in human face-selective areas. In this context, caveats possibly leading to erroneous inferences regarding mirror-symmetric coding are exposed, including the need to distinguish angular from Euclidean distances when interpreting multivariate pattern analyses. On this basis, this review argues that evidence from the fusiform face area is best explained by a view-sensitive code reflecting head angular disparity, consistent with a role of this area in face-orientation perception. Finally, the importance is stressed of explicit models relating neural properties to large-scale signals.
Dynamics of Stability of Orientation Maps Recorded with Optical Imaging.
Shumikhina, S I; Bondar, I V; Svinov, M M
2018-03-15
Orientation selectivity is an important feature of visual cortical neurons. Optical imaging of the visual cortex allows for the generation of maps of orientation selectivity that reflect the activity of large populations of neurons. To estimate the statistical significance of effects of experimental manipulations, evaluation of the stability of cortical maps over time is required. Here, we performed optical imaging recordings of the visual cortex of anesthetized adult cats. Monocular stimulation with moving clockwise square-wave gratings that continuously changed orientation and direction was used as the mapping stimulus. Recordings were repeated at various time intervals, from 15 min to 16 h. Quantification of map stability was performed on a pixel-by-pixel basis using several techniques. Map reproducibility showed clear dynamics over time. The highest degree of stability was seen in maps recorded 15-45 min apart. Averaging across all time intervals and all stimulus orientations revealed a mean shift of 2.2 ± 0.1°. There was a significant tendency for larger shifts to occur at longer time intervals. Shifts between 2.8° (mean ± 2SD) and 5° were observed more frequently at oblique orientations, while shifts greater than 5° appeared more frequently at cardinal orientations. Shifts greater than 5° occurred rarely overall (5.4% of cases) and never exceeded 11°. Shifts of 10-10.6° (0.7%) were seen occasionally at time intervals of more than 4 h. Our findings should be considered when evaluating the potential effect of experimental manipulations on orientation selectivity mapping studies. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.
Justice orientation as a moderator of the framing effect on procedural justice perception.
Sasaki, Hiroyuki; Hayashi, Yoichiro
2014-01-01
Justice orientation is a justice-relevant personality trait, which is referred to as the tendency to attend to fairness issues and to internalize justice as a moral virtue. This study examined the moderating role of justice orientation in the relationship between justice perception and response to a decision problem. The authors manipulated procedural justice and the outcome valence of the decision frame within a vignette, and measured justice orientation of 174 Japanese participants. As hypothesized, the results indicated an interaction between procedural justice and framing manipulation, which was moderated by individual differences in justice orientation. In negative framing, justice effects were larger for individuals with high rather than low justice orientation. The results are explained from a social justice perspective, and the contributions and limitations of this study are also discussed with respect to our sample and framing manipulation.
Language Teacher Identity and the Domestication of Dissent: An Exploratory Account
ERIC Educational Resources Information Center
Morgan, Brian
2016-01-01
In this article, the notion of dissent refers to a more critical, ideological orientation to advocacy for and by TESOL professionals. The notion of domestication refers to identity-forming practices in the knowledge base of language teacher education (LTE) and in professional certification processes that potentially displace this critical…
ERIC Educational Resources Information Center
Andrade, Luis M.; Lundberg, Carol A.
2018-01-01
This study investigated the ways that mission statements from 70 Hispanic-serving community colleges communicated their commitment to their Hispanic-serving function. Reference specifically to the Hispanic-serving function was absent, but references to culture and access were relatively common. Findings describe the ways culture and access were…
ERIC Educational Resources Information Center
Wharton, Sika
This annotated bibliography focuses on academic library usage of audiovisual (AV) methods of instruction, particularly for the enhancement of the reference teaching function. The bibliography's objectives are as follows: to identify current trends with regard to AV methods in library orientation and bibliographic instruction; to isolate instances…
D'Este, B R
1990-01-01
The author gives a brief chronological syntesis, starting from the XVIII century, of the various provisions issued in Italy, with particular reference to the Republic of Venice, relating to the saving of the drowned, as an introduction to the discipline of "Life-Saving" oriented swimming.
NASA Astrophysics Data System (ADS)
Heinkelmann, R.; Belda-Palazon, S.; Ferrándiz, J.; Schuh, H.
2015-08-01
For applications in Earth sciences, navigation, and astronomy the celestial (ICRF) and terrestrial (ITRF) reference frames as well as the orientation among them, the Earth orientation parameters (EOP), have to be consistent at the level of 1 mm and 0.1 mm/yr (GGOS recommendations). We assess the effect of unmodelled geophysical signals in the regularized coordinates and the sensitivity with respect to different a priori EOP and celestial reference frames. The EOP are determined using the same VLBI data but with station coordinates fixed on different TRFs. The conclusion is that within the time span of data incorporated into ITRF2008 (Altamimi, et al., 2011) the ITRF2008 and the IERS 08 C04 are consistent. This consistency involves that non-linear station motion such as unmodelled geophysical signals partly affect the IERS 08 C04 EOP. There are small but not negligible inconsistencies between the conventional celestial reference frame, ICRF2 (Fey, et al., 2009), the ITRF2008 and the conventional EOP that are quantified by comparing VTRF2008 (Böckmann, et al., 2010) and ITRF2008.
Pitch body orientation influences the perception of self-motion direction induced by optic flow.
Bourrelly, A; Vercher, J-L; Bringoux, L
2010-10-04
We studied the effect of static pitch body tilts on the perception of self-motion direction induced by a visual stimulus. Subjects were seated in front of a screen on which was projected a 3D cluster of moving dots visually simulating a forward motion of the observer with upward or downward directional biases (relative to a true earth horizontal direction). The subjects were tilted at various angles relative to gravity and were asked to estimate the direction of the perceived motion (nose-up, as during take-off or nose-down, as during landing). The data showed that body orientation proportionally affected the amount of error in the reported perceived direction (by 40% of body tilt magnitude in a range of +/-20 degrees) and these errors were systematically recorded in the direction of body tilt. As a consequence, a same visual stimulus was differently interpreted depending on body orientation. While the subjects were required to perform the task in a geocentric reference frame (i.e., relative to a gravity-related direction), they were obviously influenced by egocentric references. These results suggest that the perception of self-motion is not elaborated within an exclusive reference frame (either egocentric or geocentric) but rather results from the combined influence of both. (c) 2010 Elsevier Ireland Ltd. All rights reserved.
De Cuyper, Kathleen; Claes, Laurence; Hermans, Dirk; Pieters, Guido; Smits, Dirk
2015-01-01
We administered the Dutch Multidimensional Perfectionism Scale of Hewitt and Flett (1991, 2004) in a large student sample (N = 959) and performed a confirmatory factor analysis to test the factorial structure proposed by the original authors. The existence of a method factor referring to the negatively keyed items in the questionnaire was investigated by including it in the tested models. Next, we investigated how the 3 perfectionism dimensions are associated with the Five-factor model (FFM) of personality. The 3-factor structure originally observed by the authors was confirmed, at least when a method factor that refers to the negatively keyed items was included in the model. Self-oriented and socially prescribed perfectionism were both distinguished by low extraversion and low emotional stability. Self-oriented perfectionism's positive relationship with both conscientiousness and openness to experience differentiated the 2 perfectionism dimensions from each other. Other-oriented perfectionism was not well-characterized by the Big Five personality traits.
Morselli, Davide; Passini, Stefano
2015-11-01
In Crimes of obedience, Kelman and Hamilton argue that societies can be protected by the degeneration of authority only when citizenship is based on a strong values orientation. This reference to values may be the weakest point in their theory because they do not explicitly define these values. Nevertheless, their empirical findings suggest that the authors are referring to specific democratic principles and universal values (e.g., equality, fairness, harmlessness). In this article, a composite index known as the value-oriented citizenship (VOC) index is introduced and empirically analysed. The results confirm that the VOC index discriminates between people who relate to authority based on values rather than based on their role or on rules in general. The article discusses the utility of the VOC index to develop Kelman and Hamilton's framework further empirically as well as its implications for the analysis of the relationship between individuals and authority. Copyright © 2015 Elsevier Inc. All rights reserved.
Cavity-mode selection in spontaneous emission from oriented molecules in a microparticle.
Arnold, S; Holler, S; Goddard, N L; Griffel, G
1997-10-01
We observe preferential cavity-mode selection in spontaneous emission by oriented molecules at the surface of a microparticle. Polarization-analyzed images of a levitated microdroplet containing surface active molecules reveal a well-defined system in terms of molecular position and orientation. The measured fluorescence spectrum is compared with that of a semiclassical emission-rate-enhancement model that treats the coupling between an excited state and Mie resonances as an oscillating dipole interacting with its self-scattered field. By comparing results obtained with this theory with the relative strengths of TE to TM modes measured in the emission spectrum, we show that one can elucidate the heterogeneity of a particle from this resonant structure and determine the orientation of the emission moments relative to the phase boundary.
Problems and Limitations of Satellite Image Orientation for Determination of Height Models
NASA Astrophysics Data System (ADS)
Jacobsen, K.
2017-05-01
The usual satellite image orientation is based on bias corrected rational polynomial coefficients (RPC). The RPC are describing the direct sensor orientation of the satellite images. The locations of the projection centres today are without problems, but an accuracy limit is caused by the attitudes. Very high resolution satellites today are very agile, able to change the pointed area over 200km within 10 to 11 seconds. The corresponding fast attitude acceleration of the satellite may cause a jitter which cannot be expressed by the third order RPC, even if it is recorded by the gyros. Only a correction of the image geometry may help, but usually this will not be done. The first indication of jitter problems is shown by systematic errors of the y-parallaxes (py) for the intersection of corresponding points during the computation of ground coordinates. These y-parallaxes have a limited influence to the ground coordinates, but similar problems can be expected for the x-parallaxes, determining directly the object height. Systematic y-parallaxes are shown for Ziyuan-3 (ZY3), WorldView-2 (WV2), Pleiades, Cartosat-1, IKONOS and GeoEye. Some of them have clear jitter effects. In addition linear trends of py can be seen. Linear trends in py and tilts in of computed height models may be caused by limited accuracy of the attitude registration, but also by bias correction with affinity transformation. The bias correction is based on ground control points (GCPs). The accuracy of the GCPs usually does not cause some limitations but the identification of the GCPs in the images may be difficult. With 2-dimensional bias corrected RPC-orientation by affinity transformation tilts of the generated height models may be caused, but due to large affine image deformations some satellites, as Cartosat-1, have to be handled with bias correction by affinity transformation. Instead of a 2-dimensional RPC-orientation also a 3-dimensional orientation is possible, respecting the object height more as by 2-dimensional orientation. The 3-dimensional orientation showed advantages for orientation based on a limited number of GCPs, but in case of poor GCP distribution it may cause also negative effects. For some of the used satellites the bias correction by affinity transformation showed advantages, but for some other the bias correction by shift was leading to a better levelling of the generated height models, even if the root mean square (RMS) differences at the GCPs were larger as for bias correction by affinity transformation. The generated height models can be analyzed and corrected with reference height models. For the used data sets accurate reference height models are available, but an analysis and correction with the free of charge available SRTM digital surface model (DSM) or ALOS World 3D (AW3D30) is also possible and leads to similar results. The comparison of the generated height models with the reference DSM shows some height undulations, but the major accuracy influence is caused by tilts of the height models. Some height model undulations reach up to 50 % of the ground sampling distance (GSD), this is not negligible but it cannot be seen not so much at the standard deviations of the height. In any case an improvement of the generated height models is possible with reference height models. If such corrections are applied it compensates possible negative effects of the type of bias correction or 2-dimensional orientations against 3-dimensional handling.
Sakata, H; Taira, M; Kusunoki, M; Murata, A; Tanaka, Y
1997-08-01
Recent neurophysiological studies in alert monkeys have revealed that the parietal association cortex plays a crucial role in depth perception and visually guided hand movement. The following five classes of parietal neurons covering various aspects of these functions have been identified: (1) depth-selective visual-fixation (VF) neurons of the inferior parietal lobule (IPL), representing egocentric distance; (2) depth-movement sensitive (DMS) neurons of V5A and the ventral intraparietal (VIP) area representing direction of linear movement in 3-D space; (3) depth-rotation-sensitive (RS) neurons of V5A and the posterior parietal (PP) area representing direction of rotary movement in space; (4) visually responsive manipulation-related neurons (visual-dominant or visual-and-motor type) of the anterior intraparietal (AIP) area, representing 3-D shape or orientation (or both) of objects for manipulation; and (5) axis-orientation-selective (AOS) and surface-orientation-selective (SOS) neurons in the caudal intraparietal sulcus (cIPS) sensitive to binocular disparity and representing the 3-D orientation of the longitudinal axes and flat surfaces, respectively. Some AOS and SOS neurons are selective in both orientation and shape. Thus the dorsal visual pathway is divided into at least two subsystems, V5A, PP and VIP areas for motion vision and V6, LIP and cIPS areas for coding position and 3-D features. The cIPS sends the signals of 3-D features of objects to the AIP area, which is reciprocally connected to the ventral premotor (F5) area and plays an essential role in matching hand orientation and shaping with 3-D objects for manipulation.
Markant, Julie; Ackerman, Laura K; Nussenbaum, Kate; Amso, Dima
2016-04-01
Socioeconomic status (SES) has a documented impact on brain and cognitive development. We demonstrate that engaging spatial selective attention mechanisms may counteract this negative influence of impoverished environments on early learning. We previously used a spatial cueing task to compare target object encoding in the context of basic orienting ("facilitation") versus a spatial selective attention orienting mechanism that engages distractor suppression ("IOR"). This work showed that object encoding in the context of IOR boosted 9-month-old infants' recognition memory relative to facilitation (Markant and Amso, 2013). Here we asked whether this attention-memory link further interacted with SES in infancy. Results indicated that SES was related to memory but not attention orienting efficacy. However, the correlation between SES and memory performance was moderated by the attention mechanism engaged during encoding. SES predicted memory performance when objects were encoded with basic orienting processes, with infants from low-SES environments showing poorer memory than those from high-SES environments. However, SES did not predict memory performance among infants who engaged selective attention during encoding. Spatial selective attention engagement mitigated the effects of SES on memory and may offer an effective mechanism for promoting learning among infants at risk for poor cognitive outcomes related to SES. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.
Human Occipital and Parietal GABA Selectively Influence Visual Perception of Orientation and Size.
Song, Chen; Sandberg, Kristian; Andersen, Lau Møller; Blicher, Jakob Udby; Rees, Geraint
2017-09-13
GABA is the primary inhibitory neurotransmitter in human brain. The level of GABA varies substantially across individuals, and this variability is associated with interindividual differences in visual perception. However, it remains unclear whether the association between GABA level and visual perception reflects a general influence of visual inhibition or whether the GABA levels of different cortical regions selectively influence perception of different visual features. To address this, we studied how the GABA levels of parietal and occipital cortices related to interindividual differences in size, orientation, and brightness perception. We used visual contextual illusion as a perceptual assay since the illusion dissociates perceptual content from stimulus content and the magnitude of the illusion reflects the effect of visual inhibition. Across individuals, we observed selective correlations between the level of GABA and the magnitude of contextual illusion. Specifically, parietal GABA level correlated with size illusion magnitude but not with orientation or brightness illusion magnitude; in contrast, occipital GABA level correlated with orientation illusion magnitude but not with size or brightness illusion magnitude. Our findings reveal a region- and feature-dependent influence of GABA level on human visual perception. Parietal and occipital cortices contain, respectively, topographic maps of size and orientation preference in which neural responses to stimulus sizes and stimulus orientations are modulated by intraregional lateral connections. We propose that these lateral connections may underlie the selective influence of GABA on visual perception. SIGNIFICANCE STATEMENT GABA, the primary inhibitory neurotransmitter in human visual system, varies substantially across individuals. This interindividual variability in GABA level is linked to interindividual differences in many aspects of visual perception. However, the widespread influence of GABA raises the question of whether interindividual variability in GABA reflects an overall variability in visual inhibition and has a general influence on visual perception or whether the GABA levels of different cortical regions have selective influence on perception of different visual features. Here we report a region- and feature-dependent influence of GABA level on human visual perception. Our findings suggest that GABA level of a cortical region selectively influences perception of visual features that are topographically mapped in this region through intraregional lateral connections. Copyright © 2017 Song, Sandberg et al.
Sampath, Sujatha; Yarger, Jeffery L.
2014-11-27
Interaction with water causes shrinkage and significant changes in the structure of spider dragline silks, which has been referred to as supercontraction in the literature. Preferred orientation or alignment of protein chains with respect to the fiber axis is extensively changed during this supercontraction process. Synchrotron X-ray micro-fiber diffraction experiments have been performed on Nephila clavipes and Argiope aurantia major and minor ampullate dragline spider fibers in the native dry, contracted (by immersion in water) and restretched (from contracted) states. Changes in the orientation of β-sheet nanocrystallites and the oriented component of the amorphous network have been determined from wide-anglemore » X-ray diffraction patterns. While both the crystalline and amorphous components lose preferred orientation on wetting with water, the nano-crystallites regain their orientation on wet-restretching, whereas the oriented amorphous components only partially regain their orientation. Dragline major ampullate silks in both the species contract more than their minor ampullate silks.« less
NASA Astrophysics Data System (ADS)
Goldberg, Niels; Ospald, Felix; Schneider, Matti
2017-10-01
In this article we introduce a fiber orientation-adapted integration scheme for Tucker's orientation averaging procedure applied to non-linear material laws, based on angular central Gaussian fiber orientation distributions. This method is stable w.r.t. fiber orientations degenerating into planar states and enables the construction of orthotropic hyperelastic energies for truly orthotropic fiber orientation states. We establish a reference scenario for fitting the Tucker average of a transversely isotropic hyperelastic energy, corresponding to a uni-directional fiber orientation, to microstructural simulations, obtained by FFT-based computational homogenization of neo-Hookean constituents. We carefully discuss ideas for accelerating the identification process, leading to a tremendous speed-up compared to a naive approach. The resulting hyperelastic material map turns out to be surprisingly accurate, simple to integrate in commercial finite element codes and fast in its execution. We demonstrate the capabilities of the extracted model by a finite element analysis of a fiber reinforced chain link.
2012-01-01
Implicit in the growing interest in patient-centered outcomes research is a growing need for better evidence regarding how responses to a given intervention or treatment may vary across patients, referred to as heterogeneity of treatment effect (HTE). A variety of methods are available for exploring HTE, each associated with unique strengths and limitations. This paper reviews a selected set of methodological approaches to understanding HTE, focusing largely but not exclusively on their uses with randomized trial data. It is oriented for the “intermediate” outcomes researcher, who may already be familiar with some methods, but would value a systematic overview of both more and less familiar methods with attention to when and why they may be used. Drawing from the biomedical, statistical, epidemiological and econometrics literature, we describe the steps involved in choosing an HTE approach, focusing on whether the intent of the analysis is for exploratory, initial testing, or confirmatory testing purposes. We also map HTE methodological approaches to data considerations as well as the strengths and limitations of each approach. Methods reviewed include formal subgroup analysis, meta-analysis and meta-regression, various types of predictive risk modeling including classification and regression tree analysis, series of n-of-1 trials, latent growth and growth mixture models, quantile regression, and selected non-parametric methods. In addition to an overview of each HTE method, examples and references are provided for further reading. By guiding the selection of the methods and analysis, this review is meant to better enable outcomes researchers to understand and explore aspects of HTE in the context of patient-centered outcomes research. PMID:23234603
Cyclic Solvent Vapor Annealing for Rapid, Robust Vertical Orientation of Features in BCP Thin Films
NASA Astrophysics Data System (ADS)
Paradiso, Sean; Delaney, Kris; Fredrickson, Glenn
2015-03-01
Methods for reliably controlling block copolymer self assembly have seen much attention over the past decade as new applications for nanostructured thin films emerge in the fields of nanopatterning and lithography. While solvent assisted annealing techniques are established as flexible and simple methods for achieving long range order, solvent annealing alone exhibits a very weak thermodynamic driving force for vertically orienting domains with respect to the free surface. To address the desire for oriented features, we have investigated a cyclic solvent vapor annealing (CSVA) approach that combines the mobility benefits of solvent annealing with selective stress experienced by structures oriented parallel to the free surface as the film is repeatedly swollen with solvent and dried. Using dynamical self-consistent field theory (DSCFT) calculations, we establish the conditions under which the method significantly outperforms both static and cyclic thermal annealing and implicate the orientation selection as a consequence of the swelling/deswelling process. Our results suggest that CSVA may prove to be a potent method for the rapid formation of highly ordered, vertically oriented features in block copolymer thin films.
Induced Stress, Artificial Environment, Simulated Tactical Operations Center Model
1973-06-01
oriented 4 activities or, at best , tre application of dor:trinal i. 14 concepts to command post exercises. Unlike mechanical skills, weapon’s...training model identified as APSTRAT, an acronym indicating aptitude and strategies , be considered as a point of reference. Several instructional...post providing visual and aural sensing tasks and training objective oriented performance tasks. Vintilly, ho concludes that failure should be
Transitioning Domain Analysis: An Industry Experience.
1996-06-01
References 6 Implementation 6.1 Analysis of Operator Services’ Requirements Process 21 6.2 Preliminary Planning for FODA Training by SEI 21...an academic and industry partnership took feature oriented domain analysis ( FODA ) from a methodology that is still being defined to a well-documented...to pilot the use of the Software Engineering Institute (SEI) domain analysis methodology known as feature-oriented domain analysis ( FODA ). Supported
The Perils of Electron Microprobe Analysis of Apatite
NASA Astrophysics Data System (ADS)
Henderson, C. E.; Essene, E. J.; Wang, K. L.; Zhang, Y.
2010-12-01
Accurate electron microprobe analysis of apatite is problematic, especially for F and Cl, whose concentrations are essential in calculating a non-analyzable OH component. The issues include beam-induced sample damage and temporal variation of F and Cl X-rays; both effects are mainly dependent on beam current, beam spot size and apatite orientation [1]. To establish a rigorous analytical procedure, several oriented apatite samples, including the well-known Durango and Wilberforce fluorapatites, were analyzed for a large suite of elements, including oxygen. Careful X-ray spectroscopy was performed, including selection of appropriate analytical standards, background measurement positions and comparison of area peak factors. Polarized infrared spectra on oriented apatite samples were also collected for complementary information. The results show that when apatite samples are oriented with the c-axis parallel to the electron beam, there is significant nonlinear variation (an increase or decrease, depending on measurement conditions) of F and Cl X-ray intensities during analyses, and systematically higher-than-expected F apparent concentrations, despite the careful selection of electron beam conditions from a series of X-ray time scans and zero-time count rate extrapolation. On the other hand, when the electron beam is oriented perpendicular to the c-axis, with a ≤ 15 nA beam current and a ≥ 5 µm diameter defocused beam, F and Cl X-ray intensities do not vary or vary slowly and predictably with time, yielding quantitative analysis results for the Durango and Wilberforce apatites (both containing little OH) which are in good agreement with published wet chemical analyses. Furthermore, the OH and CO2 contents inferred for three other analyzed apatite samples are roughly consistent with infrared analyses. For example, for an apatite from Silver Crater Mine in Ontario, significant deficiency in the P site, as well as extra F, was inferred from microprobe analyses. Infrared spectra show a strong band of (CO3)2- for this apatite, which indicates a possible substitution of (CO3)2-(F)- for (PO4)3-. Other techniques to mitigate temporal variation of F and Cl, including alternative metal coatings, concurrent stage movement, and cryogenic sample-cooling were attempted, but did not eliminate the disparity in measured F concentrations between the two sample orientations. Thus, we believe that F measurements on F-rich apatite samples of unknown orientation are immediately suspect and should be regarded as upper limits of true F concentration. X-ray mapping, CL imaging and subsequent quantitative analyses show compositional variations in Na, S, Si, and REE in the Durango and Wilberforce fluorapatite samples used in this study. Problems of electron beam sensitivity, X-ray intensity anisotropy due to sample orientation, and compositional heterogeneity call into question their continued use as routine microanalysis reference materials. Microanalysts are encouraged to use more robust calibration standards, such as Cl-rich or other F-poor apatites for Ca, P, O and Cl, and MgF2 for F measurements. [1] Stormer, J.C., Pierson, M.L, and Tacker, R.C. (1993) Variation of F and Cl X-ray intensity due to anisotropic diffusion in apatite during electron microprobe analysis. Am. Min., 78, 641-648.
NASA Astrophysics Data System (ADS)
Hernández Ernst, Vera; Poigné, Axel; Los, Walter
2010-05-01
Understanding and managing the complexity of the biodiversity system in relation to global changes concerning land use and climate change with their social and economic implications is crucial to mitigate species loss and biodiversity changes in general. The sustainable development and exploitation of existing biodiversity resources require flexible and powerful infrastructures offering, on the one hand, the access to large-scale databases of observations and measures, to advanced analytical and modelling software, and to high performance computing environments and, on the other hand, the interlinkage of European scientific communities among each others and with national policies. The European Strategy Forum on Research Infrastructures (ESFRI) selected the "LifeWatch e-science and technology infrastructure for biodiversity research" as a promising development to construct facilities to contribute to meet those challenges. LifeWatch collaborates with other selected initiatives (e.g. ICOS, ANAEE, NOHA, and LTER-Europa) to achieve the integration of the infrastructures at landscape and regional scales. This should result in a cooperating cluster of such infrastructures supporting an integrated approach for data capture and transmission, data management and harmonisation. Besides, facilities for exploration, forecasting, and presentation using heterogeneous and distributed data and tools should allow the interdisciplinary scientific research at any spatial and temporal scale. LifeWatch is an example of a new generation of interoperable research infrastructures based on standards and a service-oriented architecture that allow for linkage with external resources and associated infrastructures. External data sources will be established data aggregators as the Global Biodiversity Information Facility (GBIF) for species occurrences and other EU Networks of Excellence like the Long-Term Ecological Research Network (LTER), GMES, and GEOSS for terrestrial monitoring, the MARBEF network for marine data, and the Consortium for European Taxonomic Facilities (CETAF) and its European Distributed Institute for Taxonomy (EDIT) for taxonomic data. But also "smaller" networks and "volunteer scientists" may send data (e.g. GPS supported species observations) to a LifeWatch repository. Autonomous operating wireless environmental sensors and other smart hand-held devices will contribute to increase data capture activities. In this way LifeWatch will directly underpin the development of GEOBON, the biodiversity component if GEOSS, the Global Earth observation System. To overcome all major technical difficulties imposed by the variety of currently and future technologies, protocols, data formats, etc., LifeWatch will define and use common open interfaces. For this purpose, the LifeWatch Reference Model was developed during the preparatory phase specifying the service-oriented architecture underlying the ICT-infrastructure. The Reference Model identifies key requirements and key architectural concepts to support workflows for scientific in-silico experiments, tracking of provenance, and semantic enhancement, besides meeting the functional requirements mentioned before. It provides guidelines for the specification and implementation of services and information models, defining as well a number of generic services and models. Another key issue addressed by the Reference Model is that the cooperation of many developer teams residing in many European countries has to be organized to obtain compatible results in that conformance with the specifications and policies of the Reference Model will be required. The LifeWatch Reference Model is based on the ORCHESTRA Reference Model for geospatial-oriented architectures and services networks that provides a generic framework and has been endorsed as best practice by the Open Geospatial Consortium (OGC). The LifeWatch Infrastructure will allow (interdisciplinary) scientific researchers to collaborate by creating e-Laboratories or by composing e-Services which can be shared and jointly developed. For it a long-term vision for the LifeWatch Biodiversity Workbench Portal has been developed as a one-stop application for the LifeWatch infrastructure based on existing and emerging technologies. There the user can find all available resources such as data, workflows, tools, etc. and access LifeWatch applications that integrate different resource and provides key capabilities like resource discovery and visualisation, creation of workflows, creation and management of provenance, and the support of collaborative activities. While LifeWatch developers will construct components for solving generic LifeWatch tasks, users may add their own facilities to fulfil individual needs. Examples for application of the LifeWatch Reference Model and the LifeWatch Biodiversity Workbench Portal will be given.
NASA Astrophysics Data System (ADS)
Duxbury, T. C.; Christensen, P.; Smith, D. E.; Neumann, G. A.; Kirk, R. L.; Caplinger, M. A.; Albee, A. A.; Seregina, N. V.; Neukum, G.; Archinal, B. A.
2014-12-01
The small crater Airy-0 was selected from Mariner 9 images to be the reference for the Mars prime meridian. Initial analyses in the year 2000 tied Viking Orbiter and Mars Orbiter Camera images of Airy-0 to the evolving Mars Orbiter Laser Altimeter global digital terrain model to update the location of Airy-0. Based upon this tie and radiometric tracking of landers/rovers from Earth, new expressions for the Mars spin axis direction, spin rate, and prime meridian epoch value were produced to define the orientation of the Martian surface in inertial space over time. Since the Mars Global Surveyor mission and Mars Orbiter Laser Altimeter global digital terrain model were completed some time ago, a more exhaustive study has been performed to determine the accuracy of the Airy-0 location and orientation of Mars at the standard epoch. Thermal Emission Imaging System (THEMIS) IR image cubes of the Airy and Gale crater regions were tied to the global terrain grid using precision stereo photogrammetric image processing techniques. The Airy-0 location was determined to be about 0.001° east of its predicted location using the currently defined International Astronomical Union (IAU) prime meridian location. Information on this new location and how it was derived will be provided to the NASA Mars Exploration Program Geodesy and Cartography Working Group for their assessment. This NASA group will make a recommendation to the IAU Working Group on Cartographic Coordinates and Rotational Elements to update the expression for the Mars spin axis direction, spin rate, and prime meridian location.
Li, Ya-tang; Liu, Bao-hua; Chou, Xiao-lin; Zhang, Li I.
2015-01-01
In the primary visual cortex (V1), orientation-selective neurons can be categorized into simple and complex cells primarily based on their receptive field (RF) structures. In mouse V1, although previous studies have examined the excitatory/inhibitory interplay underlying orientation selectivity (OS) of simple cells, the synaptic bases for that of complex cells have remained obscure. Here, by combining in vivo loose-patch and whole-cell recordings, we found that complex cells, identified by their overlapping on/off subfields, had significantly weaker OS than simple cells at both spiking and subthreshold membrane potential response levels. Voltage-clamp recordings further revealed that although excitatory inputs to complex and simple cells exhibited a similar degree of OS, inhibition in complex cells was more narrowly tuned than excitation, whereas in simple cells inhibition was more broadly tuned than excitation. The differential inhibitory tuning can primarily account for the difference in OS between complex and simple cells. Interestingly, the differential synaptic tuning correlated well with the spatial organization of synaptic input: the inhibitory visual RF in complex cells was more elongated in shape than its excitatory counterpart and also was more elongated than that in simple cells. Together, our results demonstrate that OS of complex and simple cells is differentially shaped by cortical inhibition based on its orientation tuning profile relative to excitation, which is contributed at least partially by the spatial organization of RFs of presynaptic inhibitory neurons. SIGNIFICANCE STATEMENT Simple and complex cells, two classes of principal neurons in the primary visual cortex (V1), are generally thought to be equally selective for orientation. In mouse V1, we report that complex cells, identified by their overlapping on/off subfields, has significantly weaker orientation selectivity (OS) than simple cells. This can be primarily attributed to the differential tuning selectivity of inhibitory synaptic input: inhibition in complex cells is more narrowly tuned than excitation, whereas in simple cells inhibition is more broadly tuned than excitation. In addition, there is a good correlation between inhibitory tuning selectivity and the spatial organization of inhibitory inputs. These complex and simple cells with differential degree of OS may provide functionally distinct signals to different downstream targets. PMID:26245969
Li, Ya-tang; Liu, Bao-hua; Chou, Xiao-lin; Zhang, Li I; Tao, Huizhong W
2015-08-05
In the primary visual cortex (V1), orientation-selective neurons can be categorized into simple and complex cells primarily based on their receptive field (RF) structures. In mouse V1, although previous studies have examined the excitatory/inhibitory interplay underlying orientation selectivity (OS) of simple cells, the synaptic bases for that of complex cells have remained obscure. Here, by combining in vivo loose-patch and whole-cell recordings, we found that complex cells, identified by their overlapping on/off subfields, had significantly weaker OS than simple cells at both spiking and subthreshold membrane potential response levels. Voltage-clamp recordings further revealed that although excitatory inputs to complex and simple cells exhibited a similar degree of OS, inhibition in complex cells was more narrowly tuned than excitation, whereas in simple cells inhibition was more broadly tuned than excitation. The differential inhibitory tuning can primarily account for the difference in OS between complex and simple cells. Interestingly, the differential synaptic tuning correlated well with the spatial organization of synaptic input: the inhibitory visual RF in complex cells was more elongated in shape than its excitatory counterpart and also was more elongated than that in simple cells. Together, our results demonstrate that OS of complex and simple cells is differentially shaped by cortical inhibition based on its orientation tuning profile relative to excitation, which is contributed at least partially by the spatial organization of RFs of presynaptic inhibitory neurons. Simple and complex cells, two classes of principal neurons in the primary visual cortex (V1), are generally thought to be equally selective for orientation. In mouse V1, we report that complex cells, identified by their overlapping on/off subfields, has significantly weaker orientation selectivity (OS) than simple cells. This can be primarily attributed to the differential tuning selectivity of inhibitory synaptic input: inhibition in complex cells is more narrowly tuned than excitation, whereas in simple cells inhibition is more broadly tuned than excitation. In addition, there is a good correlation between inhibitory tuning selectivity and the spatial organization of inhibitory inputs. These complex and simple cells with differential degree of OS may provide functionally distinct signals to different downstream targets. Copyright © 2015 the authors 0270-6474/15/3511081-13$15.00/0.
NASA Astrophysics Data System (ADS)
Nargund-Joshi, Vanashri
This study explores the concepts and behaviors, otherwise referred to as orientations, of six Indian science teachers and the alignment of these orientations to the 2005 India National Curriculum Framework (NCF-2005). Differences in teachers' orientations across grade bands (elementary, middle, and secondary) and school types (public versus private) are also examined to determine how contextual factors may influence this alignment. First, a content analysis of the NCF-2005 was completed to identify the overarching principles of the NCF-2005 and goals specific to the teaching and learning of science. Interviews with school principals were also analyzed to understand how the goals of NCF-2005 were communicated to schools and teachers. Together, these data sources served to answer research question one. Next, profiles were created based on three interviews with each teacher and several observations of their teaching. These profiles provide a point of reference for answering the remaining three research questions. Findings include teacher's orientations falling along a continuum from traditionalist in nature to inquiry/constructivist in nature. Stark contrasts were found between traditionalist orientations and the goals of NCF-2005, with much of this contrast due to the limited pedagogical content knowledge these teachers have regarding students' scientific thinking, curriculum design, instructional strategies, and assessment. Inquiry/constructivist teachers' orientations, while more in line with reform, still have a few key areas of pedagogical content knowledge needing attention (e.g., knowledge of assessment and a variety of purposes for constructivist instructional strategies). In response to the final research question, several contextual factors contributed to teachers' orientations including environmental constraints, such as limited resources and large class sizes, cultural testing pressures, and limited accessibility to professional development. Suggestions for improving the implementation of NCF-2005 in India's classrooms are discussed according to various stakeholders (e.g., policy makers, curriculum designers, professional developers).
A three-dimensional axis for the study of femoral neck orientation
Bonneau, Noémie; Libourel, Paul-Antoine; Simonis, Caroline; Puymerail, Laurent; Baylac, Michel; Tardieu, Christine; Gagey, Olivier
2012-01-01
A common problem in the quantification of the orientation of the femoral neck is the difficulty to determine its true axis; however, this axis is typically estimated visually only. Moreover, the orientation of the femoral neck is commonly analysed using angles that are dependent on anatomical planes of reference and only quantify the orientation in two dimensions. The purpose of this study is to establish a method to determine the three-dimensional orientation of the femoral neck using a three-dimensional model. An accurate determination of the femoral neck axis requires a reconsideration of the complex architecture of the proximal femur. The morphology of the femoral neck results from both the medial and arcuate trabecular systems, and the asymmetry of the cortical bone. Given these considerations, two alternative models, in addition to the cylindrical one frequently assumed, were tested. The surface geometry of the femoral neck was subsequently used to fit one cylinder, two cylinders and successive cross-sectional ellipses. The model based on successive ellipses provided a significantly smaller average deviation than the two other models (P < 0.001) and reduced the observer-induced measurement error. Comparisons with traditional measurements and analyses on a sample of 91 femora were also performed to assess the validity of the model based on successive ellipses. This study provides a semi-automatic and accurate method for the determination of the functional three-dimensional femoral neck orientation avoiding the use of a reference plane. This innovative method has important implications for future studies that aim to document and understand the change in the orientation of the femoral neck associated with the acquisition of a bipedal gait in humans. Moreover, the precise determination of the three-dimensional orientation has implications in current research involved in developing clinical applications in diagnosis, hip surgery and rehabilitation. PMID:22967192
Functional implications of orientation maps in primary visual cortex
NASA Astrophysics Data System (ADS)
Koch, Erin; Jin, Jianzhong; Alonso, Jose M.; Zaidi, Qasim
2016-11-01
Stimulus orientation in the primary visual cortex of primates and carnivores is mapped as iso-orientation domains radiating from pinwheel centres, where orientation preferences of neighbouring cells change circularly. Whether this orientation map has a function is currently debated, because many mammals, such as rodents, do not have such maps. Here we show that two fundamental properties of visual cortical responses, contrast saturation and cross-orientation suppression, are stronger within cat iso-orientation domains than at pinwheel centres. These differences develop when excitation (not normalization) from neighbouring oriented neurons is applied to different cortical orientation domains and then balanced by inhibition from un-oriented neurons. The functions of the pinwheel mosaic emerge from these local intra-cortical computations: Narrower tuning, greater cross-orientation suppression and higher contrast gain of iso-orientation cells facilitate extraction of object contours from images, whereas broader tuning, greater linearity and less suppression of pinwheel cells generate selectivity for surface patterns and textures.
Ji, Young Rae; Warrier, Sunita; Jiang, Tao
2018-01-01
The orientation of hair bundles on top of sensory hair cells (HCs) in neuromasts of the lateral line system allows fish to detect direction of water flow. Each neuromast shows hair bundles arranged in two opposing directions and each afferent neuron innervates only HCs of the same orientation. Previously, we showed that this opposition is established by expression of Emx2 in half of the HCs, where it mediates hair bundle reversal (Jiang et al., 2017). Here, we show that Emx2 also regulates neuronal selection: afferent neurons innervate either Emx2-positive or negative HCs. In emx2 knockout and gain-of-function neuromasts, all HCs are unidirectional and the innervation patterns and physiological responses of the afferent neurons are dependent on the presence or absence of Emx2. Our results indicate that Emx2 mediates the directional selectivity of neuromasts by two distinct processes: regulating hair bundle orientation in HCs and selecting afferent neuronal targets. PMID:29671737
NASA Astrophysics Data System (ADS)
Kankipati, Venkata Varun
This thesis presents a method to determine the angular orientation of a projectile in flight, by mechanically scanning a linearly polarized, microwave reference source. In particular, the research focuses on real time measurement of the roll angle. A 10 GHz, linearly polarized electromagnetic wave is radiated toward the projectile by means of a 10 dB horn antenna. The projectile is equipped with a backward facing 10 dB horn antenna, which has orientation, namely roll angle, sensitivity. The response of the received signal follows a cosine law, producing a maximum when the receiver orientation is aligned with the transmitting polarization. As expected, the peak response shifts in response to the roll-angle, however, unambiguous recovery of the angle requires synchronization with the polarization orientation of the source. This has been achieved through the use of a unique transmitter power sequence, which includes a start-of-scan and end-of-scan time stamp. Based on the above concept, a complete system comprising a polarization scanning reference source, the receiving antenna mounted on a vehicle, and pertinent electronic components, has been tested for both line of sight and non-line of sight applications. The transmitter antenna, mounted on a computer controlled stepper motor allowed source polarization to be scanned from -90° to 90° in 0.3 seconds. The receiving antenna continuously samples the received electromagnetic background at the source frequency and uses a RF detector and a data acquisition system to record the subsequent time-varying voltage signal, which is processed to recover the roll-angle. Measurements in an anechoic chamber were used to confirm the efficacy of the system and field trials, using a transmitter power of 2 W, were successfully demonstrated over a distance of 0.15 miles. The distance limit can be extended by increasing the transmitter power, receiver sensitivity and increase source frequency.
Polarization-dependent DANES study on vertically-aligned ZnO nanorods
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sun, Chengjun; Park, Chang-In; Jin, Zhenlan
2016-05-01
The local structural and local density of states of vertically-aligned ZnO nanorods were examined by using a polarization-dependent diffraction anomalous near edge structure (DANES) measurements from c-oriented ZnO nanorods at the Zn K edge with the incident x-ray electric field parallel and perpendicular to the x-ray momentum transfer direction. Orientation-dependent local structures determined by DANES were comparable with polarization-dependent EXAFS results. Unlike other techniques, polarization-dependent DANES can uniquely describe the orientation-dependent local structural properties and the local density of states of a selected element in selected-phased crystals of compounds or mixed-phased structures.
W-band PELDOR with 1 kW microwave power: molecular geometry, flexibility and exchange coupling.
Reginsson, Gunnar W; Hunter, Robert I; Cruickshank, Paul A S; Bolton, David R; Sigurdsson, Snorri Th; Smith, Graham M; Schiemann, Olav
2012-03-01
A technique that is increasingly being used to determine the structure and conformational flexibility of biomacromolecules is Pulsed Electron-Electron Double Resonance (PELDOR or DEER), an Electron Paramagnetic Resonance (EPR) based technique. At X-band frequencies (9.5 GHz), PELDOR is capable of precisely measuring distances in the range of 1.5-8 nm between paramagnetic centres but the orientation selectivity is weak. In contrast, working at higher frequencies increases the orientation selection but usually at the expense of decreased microwave power and PELDOR modulation depth. Here it is shown that a home-built high-power pulsed W-band EPR spectrometer (HiPER) with a large instantaneous bandwidth enables one to achieve PELDOR data with a high degree of orientation selectivity and large modulation depths. We demonstrate a measurement methodology that gives a set of PELDOR time traces that yield highly constrained data sets. Simulating the resulting time traces provides a deeper insight into the conformational flexibility and exchange coupling of three bisnitroxide model systems. These measurements provide strong evidence that W-band PELDOR may prove to be an accurate and quantitative tool in assessing the relative orientations of nitroxide spin labels and to correlate those orientations to the underlying biological structure and dynamics. Copyright © 2012 Elsevier Inc. All rights reserved.
[Orienting reflex: "targeting reaction" and "searchlight of attention"].
Sokolov, E N; Nezlina, N I; Polianskiĭ, V B; Evtikhin, D V
2001-01-01
The concept of orienting reflex based on the principle of vector coding of cognitive and executive processes is proposed. The orienting reflex to non-signal and signal stimuli is a set of orienting reactions: motor, autonomic, neuronal, and subjective emphasizing new and significant stimuli. Two basic mechanisms can be identified within the orienting reflex: a "targeting reaction" and a "searchlight of attention". In the visual system the first one consists in a foveation of a target stimulus. The foveation is performed with participation of premotor neurons excited by saccadic command neurons of the superior colliculi. The "searchlight of attention" is based on the resonance of gamma-oscillations in the reticular thalamus selectively enhancing responses of cortical neurons (involuntary attention). The novelty signal is generated in novelty neurons of the hippocampus, which are selectively tuned to a repeatedly presented standard stimulus. The selective tuning is caused by the depression of plastic synapses representing a "neuronal model" of the standard stimulus. A mismatch of the novel stimulus with the established neuronal model gives rise to a "novelty signal" enhancing the novel input. The novelty signal inhibits current conditioned reflexes (external inhibition) contributing to redirecting the behavior. By triggering the expression of early genes the novelty signal initiates the formation of the long-term memory connected with neoneurogenesis.
Sanchez-Barcelo, Emilio J; Mediavilla, Maria D; Alonso-Gonzalez, Carolina; Reiter, Russel J
2012-06-01
The possible oncostatic properties of melatonin on different types of neoplasias have been studied especially in hormone-dependent adenocarcinomas. Despite the promising results of these experimental investigations, the use of melatonin in breast cancer treatment in humans is still uncommon. This article reviews the usefulness of this indoleamine for specific aspects of breast cancer management, particularly in reference to melatonin's antiestrogenic and antioxidant properties: i) treatments oriented to breast cancer prevention, especially when the risk factors are obesity, steroid hormone treatment or chronodisruption by exposure to light at night (LAN); ii) treatment of the side effects associated with chemo- or radiotherapy. The clinical utility of melatonin depends on the appropriate identification of its actions. Because of its SERM (selective estrogen receptor modulators) and SEEM (selective estrogen enzyme modulators) properties, and its virtual absence of contraindications, melatonin could be an excellent adjuvant with the drugs currently used for breast cancer prevention (antiestrogens and antiaromatases). The antioxidant actions also make melatonin a suitable treatment to reduce oxidative stress associated with chemotherapy, especially with anthracyclines, and radiotherapy.
Decision Tree Repository and Rule Set Based Mingjiang River Estuarine Wetlands Classifaction
NASA Astrophysics Data System (ADS)
Zhang, W.; Li, X.; Xiao, W.
2018-05-01
The increasing urbanization and industrialization have led to wetland losses in estuarine area of Mingjiang River over past three decades. There has been increasing attention given to produce wetland inventories using remote sensing and GIS technology. Due to inconsistency training site and training sample, traditionally pixel-based image classification methods can't achieve a comparable result within different organizations. Meanwhile, object-oriented image classification technique shows grate potential to solve this problem and Landsat moderate resolution remote sensing images are widely used to fulfill this requirement. Firstly, the standardized atmospheric correct, spectrally high fidelity texture feature enhancement was conducted before implementing the object-oriented wetland classification method in eCognition. Secondly, we performed the multi-scale segmentation procedure, taking the scale, hue, shape, compactness and smoothness of the image into account to get the appropriate parameters, using the top and down region merge algorithm from single pixel level, the optimal texture segmentation scale for different types of features is confirmed. Then, the segmented object is used as the classification unit to calculate the spectral information such as Mean value, Maximum value, Minimum value, Brightness value and the Normalized value. The Area, length, Tightness and the Shape rule of the image object Spatial features and texture features such as Mean, Variance and Entropy of image objects are used as classification features of training samples. Based on the reference images and the sampling points of on-the-spot investigation, typical training samples are selected uniformly and randomly for each type of ground objects. The spectral, texture and spatial characteristics of each type of feature in each feature layer corresponding to the range of values are used to create the decision tree repository. Finally, with the help of high resolution reference images, the random sampling method is used to conduct the field investigation, achieve an overall accuracy of 90.31 %, and the Kappa coefficient is 0.88. The classification method based on decision tree threshold values and rule set developed by the repository, outperforms the results obtained from the traditional methodology. Our decision tree repository and rule set based object-oriented classification technique was an effective method for producing comparable and consistency wetlands data set.
Gueguen, Marc; Vuillerme, Nicolas; Isableu, Brice
2012-01-01
Background The selection of appropriate frames of reference (FOR) is a key factor in the elaboration of spatial perception and the production of robust interaction with our environment. The extent to which we perceive the head axis orientation (subjective head orientation, SHO) with both accuracy and precision likely contributes to the efficiency of these spatial interactions. A first goal of this study was to investigate the relative contribution of both the visual and egocentric FOR (centre-of-mass) in the SHO processing. A second goal was to investigate humans' ability to process SHO in various sensory response modalities (visual, haptic and visuo-haptic), and the way they modify the reliance to either the visual or egocentric FORs. A third goal was to question whether subjects combined visual and haptic cues optimally to increase SHO certainty and to decrease the FORs disruption effect. Methodology/Principal Findings Thirteen subjects were asked to indicate their SHO while the visual and/or egocentric FORs were deviated. Four results emerged from our study. First, visual rod settings to SHO were altered by the tilted visual frame but not by the egocentric FOR alteration, whereas no haptic settings alteration was observed whether due to the egocentric FOR alteration or the tilted visual frame. These results are modulated by individual analysis. Second, visual and egocentric FOR dependency appear to be negatively correlated. Third, the response modality enrichment appears to improve SHO. Fourth, several combination rules of the visuo-haptic cues such as the Maximum Likelihood Estimation (MLE), Winner-Take-All (WTA) or Unweighted Mean (UWM) rule seem to account for SHO improvements. However, the UWM rule seems to best account for the improvement of visuo-haptic estimates, especially in situations with high FOR incongruence. Finally, the data also indicated that FOR reliance resulted from the application of UWM rule. This was observed more particularly, in the visual dependent subject. Conclusions: Taken together, these findings emphasize the importance of identifying individual spatial FOR preferences to assess the efficiency of our interaction with the environment whilst performing spatial tasks. PMID:22509295
Does Changing the Reference Frame Affect Infant Categorization of the Spatial Relation BETWEEN?
ERIC Educational Resources Information Center
Quinn, Paul C.; Doran, Matthew M.; Papafragou, Anna
2011-01-01
Past research has shown that variation in the target objects depicting a given spatial relation disrupts the formation of a category representation for that relation. In the current research, we asked whether changing the orientation of the referent frame depicting the spatial relation would also disrupt the formation of a category representation…
Using Picture Books as a Vehicle to Teach Young Children about Social Justice
ERIC Educational Resources Information Center
Dever, Martha Taylor; Sorenson, Brooke; Broderick, Julie
2005-01-01
Most teachers and administrators have witnessed children using a derogatory reference to a group of people as a put down. Put downs usually reference non-mainstream groups who are different in ethnicity, gender, religion, ability, sexual orientation, class, or appearance. Hurtful name calling is but one example of how children express prejudiced…
Aerospace-Oriented Units for Use in Humanities Classes, Grades 7-12.
ERIC Educational Resources Information Center
Rademacher, Jean, Ed.; Williams, Mary H., Ed.
This curriculum guide, funded under ESEA Title 3, is designed to help students in English and social studies classes develop a global frame of reference and increase their awareness of advances in air and space technology. The history of aerospace technology from the first mythological references to flight to the space exploration of the future is…
Laminar Neural Field Model of Laterally Propagating Waves of Orientation Selectivity
2015-01-01
We construct a laminar neural-field model of primary visual cortex (V1) consisting of a superficial layer of neurons that encode the spatial location and orientation of a local visual stimulus coupled to a deep layer of neurons that only encode spatial location. The spatially-structured connections in the deep layer support the propagation of a traveling front, which then drives propagating orientation-dependent activity in the superficial layer. Using a combination of mathematical analysis and numerical simulations, we establish that the existence of a coherent orientation-selective wave relies on the presence of weak, long-range connections in the superficial layer that couple cells of similar orientation preference. Moreover, the wave persists in the presence of feedback from the superficial layer to the deep layer. Our results are consistent with recent experimental studies that indicate that deep and superficial layers work in tandem to determine the patterns of cortical activity observed in vivo. PMID:26491877
Interactions between motion and form processing in the human visual system.
Mather, George; Pavan, Andrea; Bellacosa Marotti, Rosilari; Campana, Gianluca; Casco, Clara
2013-01-01
The predominant view of motion and form processing in the human visual system assumes that these two attributes are handled by separate and independent modules. Motion processing involves filtering by direction-selective sensors, followed by integration to solve the aperture problem. Form processing involves filtering by orientation-selective and size-selective receptive fields, followed by integration to encode object shape. It has long been known that motion signals can influence form processing in the well-known Gestalt principle of common fate; texture elements which share a common motion property are grouped into a single contour or texture region. However, recent research in psychophysics and neuroscience indicates that the influence of form signals on motion processing is more extensive than previously thought. First, the salience and apparent direction of moving lines depends on how the local orientation and direction of motion combine to match the receptive field properties of motion-selective neurons. Second, orientation signals generated by "motion-streaks" influence motion processing; motion sensitivity, apparent direction and adaptation are affected by simultaneously present orientation signals. Third, form signals generated by human body shape influence biological motion processing, as revealed by studies using point-light motion stimuli. Thus, form-motion integration seems to occur at several different levels of cortical processing, from V1 to STS.
Neural Correlate of the Thatcher Face Illusion in a Monkey Face-Selective Patch.
Taubert, Jessica; Van Belle, Goedele; Vanduffel, Wim; Rossion, Bruno; Vogels, Rufin
2015-07-08
Compelling evidence that our sensitivity to facial structure is conserved across the primate order comes from studies of the "Thatcher face illusion": humans and monkeys notice changes in the orientation of facial features (e.g., the eyes) only when faces are upright, not when faces are upside down. Although it is presumed that face perception in primates depends on face-selective neurons in the inferior temporal (IT) cortex, it is not known whether these neurons respond differentially to upright faces with inverted features. Using microelectrodes guided by functional MRI mapping, we recorded cell responses in three regions of monkey IT cortex. We report an interaction in the middle lateral face patch (ML) between the global orientation of a face and the local orientation of its eyes, a response profile consistent with the perception of the Thatcher illusion. This increased sensitivity to eye orientation in upright faces resisted changes in screen location and was not found among face-selective neurons in other areas of IT cortex, including neurons in another face-selective region, the anterior lateral face patch. We conclude that the Thatcher face illusion is correlated with a pattern of activity in the ML that encodes faces according to a flexible holistic template. Copyright © 2015 the authors 0270-6474/15/359872-07$15.00/0.
Interactions between motion and form processing in the human visual system
Mather, George; Pavan, Andrea; Bellacosa Marotti, Rosilari; Campana, Gianluca; Casco, Clara
2013-01-01
The predominant view of motion and form processing in the human visual system assumes that these two attributes are handled by separate and independent modules. Motion processing involves filtering by direction-selective sensors, followed by integration to solve the aperture problem. Form processing involves filtering by orientation-selective and size-selective receptive fields, followed by integration to encode object shape. It has long been known that motion signals can influence form processing in the well-known Gestalt principle of common fate; texture elements which share a common motion property are grouped into a single contour or texture region. However, recent research in psychophysics and neuroscience indicates that the influence of form signals on motion processing is more extensive than previously thought. First, the salience and apparent direction of moving lines depends on how the local orientation and direction of motion combine to match the receptive field properties of motion-selective neurons. Second, orientation signals generated by “motion-streaks” influence motion processing; motion sensitivity, apparent direction and adaptation are affected by simultaneously present orientation signals. Third, form signals generated by human body shape influence biological motion processing, as revealed by studies using point-light motion stimuli. Thus, form-motion integration seems to occur at several different levels of cortical processing, from V1 to STS. PMID:23730286
Sleight, C C; Prinz, P M
1985-11-01
In this study language-disordered and nondisordered children viewed a nonverbal film, wrote the story, and narrated it to language-disordered and nondisordered peers who were unfamiliar with the film. The narratives were analyzed for the use of abstracts, orientations (background information), and codas. Language-disordered children made fewer references to the orientation clauses of props and activities than nondisordered children. Neither group modified their language in the areas examined to take into account the communicative status of their listeners. Therapeutic implications for the language-disordered children are presented as are suggestions for future research.
The neural code for face orientation in the human fusiform face area.
Ramírez, Fernando M; Cichy, Radoslaw M; Allefeld, Carsten; Haynes, John-Dylan
2014-09-03
Humans recognize faces and objects with high speed and accuracy regardless of their orientation. Recent studies have proposed that orientation invariance in face recognition involves an intermediate representation where neural responses are similar for mirror-symmetric views. Here, we used fMRI, multivariate pattern analysis, and computational modeling to investigate the neural encoding of faces and vehicles at different rotational angles. Corroborating previous studies, we demonstrate a representation of face orientation in the fusiform face-selective area (FFA). We go beyond these studies by showing that this representation is category-selective and tolerant to retinal translation. Critically, by controlling for low-level confounds, we found the representation of orientation in FFA to be compatible with a linear angle code. Aspects of mirror-symmetric coding cannot be ruled out when FFA mean activity levels are considered as a dimension of coding. Finally, we used a parametric family of computational models, involving a biased sampling of view-tuned neuronal clusters, to compare different face angle encoding models. The best fitting model exhibited a predominance of neuronal clusters tuned to frontal views of faces. In sum, our findings suggest a category-selective and monotonic code of face orientation in the human FFA, in line with primate electrophysiology studies that observed mirror-symmetric tuning of neural responses at higher stages of the visual system, beyond the putative homolog of human FFA. Copyright © 2014 the authors 0270-6474/14/3412155-13$15.00/0.
NASA Astrophysics Data System (ADS)
Ghafaryasl, Babak; Baart, Robert; de Boer, Johannes F.; Vermeer, Koenraad A.; van Vliet, Lucas J.
2017-02-01
Optical coherence tomography (OCT) yields high-resolution, three-dimensional images of the retina. A better understanding of retinal nerve fiber bundle (RNFB) trajectories in combination with visual field data may be used for future diagnosis and monitoring of glaucoma. However, manual tracing of these bundles is a tedious task. In this work, we present an automatic technique to estimate the orientation of RNFBs from volumetric OCT scans. Our method consists of several steps, starting from automatic segmentation of the RNFL. Then, a stack of en face images around the posterior nerve fiber layer interface was extracted. The image showing the best visibility of RNFB trajectories was selected for further processing. After denoising the selected en face image, a semblance structure-oriented filter was applied to probe the strength of local linear structure in a discrete set of orientations creating an orientation space. Gaussian filtering along the orientation axis in this space is used to find the dominant orientation. Next, a confidence map was created to supplement the estimated orientation. This confidence map was used as pixel weight in normalized convolution to regularize the semblance filter response after which a new orientation estimate can be obtained. Finally, after several iterations an orientation field corresponding to the strongest local orientation was obtained. The RNFB orientations of six macular scans from three subjects were estimated. For all scans, visual inspection shows a good agreement between the estimated orientation fields and the RNFB trajectories in the en face images. Additionally, a good correlation between the orientation fields of two scans of the same subject was observed. Our method was also applied to a larger field of view around the macula. Manual tracing of the RNFB trajectories shows a good agreement with the automatically obtained streamlines obtained by fiber tracking.
ERIC Educational Resources Information Center
Center for Applied Linguistics, Washington, DC. Language and Orientation Resource Center.
An annotated bibliography of materials for the orientation of refugees and their sponsors is a supplement to "A Guide to Orientation Materials for Indochinese Refugees and their Sponsors," and includes 40 entries for materials pertinent to many other, non-Indochinese refugee groups. The materials are grouped alphabetically by the…
Ma, Hing Keung
2006-01-01
Moral competence refers to the orientation to perform altruistic behavior and the ability to judge moral issues logically, consistently and at an advanced level of development. A brief review of the concepts of altruism and justice is presented. The gender and cultural issues are also discussed. The contents of moral competence program units include four major topics: (1) Fairness, (2) Proper conduct (mainly altruistic and prosocial orientation), (3) Responsibility and altruistic orientation, and (4) Integrity and fairness. The general goal is to help students to develop an altruistic orientation and a judgment structure of a high level of justice. This paper is part of the development of the positive youth development program in Hong Kong.
NASA Technical Reports Server (NTRS)
Foxlin, Eric M. (Inventor)
2004-01-01
A self contained sensor apparatus generates a signal that corresponds to at least two of the three orientational aspects of yaw, pitch and roll of a human-scale body, relative to an external reference frame. A sensor generates first sensor signals that correspond to rotational accelerations or rates of the body about certain body axes. The sensor may be mounted to the body. Coupled to the sensor is a signal processor for generating orientation signals relative to the external reference frame that correspond to the angular rate or acceleration signals. The first sensor signals are impervious to interference from electromagnetic, acoustic, optical and mechanical sources. The sensors may be rate sensors. An integrator may integrate the rate signal over time. A drift compensator is coupled to the rate sensors and the integrator. The drift compensator may include a gravitational tilt sensor or a magnetic field sensor or both. A verifier periodically measures the orientation of the body by a means different from the drift sensitive sate sensors. The verifier may take into account characteristic features of human motion, such as stillness periods. The drift compensator may be, in part, a Kalman filter, which may utilize statistical data about human head motion.
NASA Technical Reports Server (NTRS)
Foxlin, Eric M. (Inventor)
2000-01-01
A self contained sensor apparatus generates a signal that corresponds to at least two of the three orientational aspects of yaw, pitch and roll of a human-scale body, relative to an external reference frame. A sensor generates first sensor signals that correspond to rotational accelerations or rates of the body about certain body axes. The sensor may be mounted to the body. Coupled to the sensor is a signal processor for generating orientation signals relative to the external reference frame that correspond to the angular rate or acceleration signals. The first sensor signals are impervious to interference from electromagnetic, acoustic, optical and mechanical sources. The sensors may be rate sensors. An integrator may integrate the rate signal over time. A drift compensator is coupled to the rate sensors and the integrator. The drift compensator may include a gravitational tilt sensor or a magnetic field sensor or both. A verifier periodically measures the orientation of the body by a means different from the drift sensitive rate sensors. The verifier may take into account characteristic features of human motion, such as stillness periods. The drift compensator may be, in part, a Kalman filter, which may utilize statistical data about human head motion.
NASA Technical Reports Server (NTRS)
Foxlin, Eric M. (Inventor)
2002-01-01
A self contained sensor apparatus generates a signal that corresponds to at least two of the three orientational aspects of yaw, pitch and roll of a human-scale body, relative to an external reference frame. A sensor generates first sensor signals that correspond to rotational accelerations or rates of the body about certain body axes. The sensor may be mounted to the body. Coupled to the sensor is a signal processor for generating orientation signals relative to the external reference frame that correspond to the angular rate or acceleration signals. The first sensor signals are impervious to interference from electromagnetic, acoustic, optical and mechanical sources. The sensors may be rate sensors. An integrator may integrate the rate signal over time. A drift compensator is coupled to the rate sensors and the integrator. The drift compensator may include a gravitational tilt sensor or a magnetic field sensor or both. A verifier periodically measures the orientation of the body by a means different from the drift sensitive rate sensors. The verifier may take into account characteristic features of human motion, such as stillness periods. The drift compensator may be, in part, a Kalman filter, which may utilize statistical data about human head motion.
NASA Technical Reports Server (NTRS)
Foxlin, Eric M. (Inventor)
1998-01-01
A self contained sensor apparatus generates a signal that corresponds to at least two of the three orientational aspects of yaw, pitch and roll of a human-scale body, relative to an external reference frame. A sensor generates first sensor signals that correspond to rotational accelerations or rates of the body about certain body axes. The sensor may be mounted to the body. Coupled to the sensor is a signal processor for generating orientation signals relative to the external reference frame that correspond to the angular rate or acceleration signals. The first sensor signals are impervious to interference from electromagnetic, acoustic, optical and mechanical sources. The sensors may be rate sensors. An integrator may integrate the rate signal over time. A drift compensator is coupled to the rate sensors and the integrator. The drift compensator may include a gravitational tilt sensor or a magnetic field sensor or both. A verifier periodically measures the orientation of the body by a means different from the drift sensitive rate sensors. The verifier may take into account characteristic features of human motion, such as stillness periods. The drift compensator may be, in part, a Kalman filter, which may utilize statistical data about human head motion.
NASA Technical Reports Server (NTRS)
Foxlin, Eric M. (Inventor)
1997-01-01
A self contained sensor apparatus generates a signal that corresponds to at least two of the three orientational aspects of yaw, pitch and roll of a human-scale body, relative to an external reference frame. A sensor generates first sensor signals that correspond to rotational accelerations or rates of the body about certain body axes. The sensor may be mounted to the body. Coupled to the sensor is a signal processor for generating orientation signals relative to the external reference frame that correspond to the angular rate or acceleration signals. The first sensor signals are impervious to interference from electromagnetic, acoustic, optical and mechanical sources. The sensors may be rate sensors. An integrator may integrate the rate signal over time. A drift compensator is coupled to the rate sensors and the integrator. The drift compensator may include a gravitational tilt sensor or a magnetic field sensor or both. A verifier periodically measures the orientation of the body by a means different from the drift sensitive rate sensors. The verifier may take into account characteristic features of human motion, such as stillness periods. The drift compensator may be, in part, a Kalman filter, which may utilize statistical data about human head motion.
NASA Astrophysics Data System (ADS)
Du, J.; Chen, C.; Lesur, V.; Wang, L.
2015-07-01
General expressions of magnetic vector (MV) and magnetic gradient tensor (MGT) in terms of the first- and second-order derivatives of spherical harmonics at different degrees/orders are relatively complicated and singular at the poles. In this paper, we derived alternative non-singular expressions for the MV, the MGT and also the third-order partial derivatives of the magnetic potential field in the local north-oriented reference frame. Using our newly derived formulae, the magnetic potential, vector and gradient tensor fields and also the third-order partial derivatives of the magnetic potential field at an altitude of 300 km are calculated based on a global lithospheric magnetic field model GRIMM_L120 (GFZ Reference Internal Magnetic Model, version 0.0) with spherical harmonic degrees 16-90. The corresponding results at the poles are discussed and the validity of the derived formulas is verified using the Laplace equation of the magnetic potential field.
Baron, Ellen Jo; D'Souza, Holly; Qi Wang, Andrew; Gibbs, David L.
2008-01-01
The Biomic V3 microbiology system identifies bacteria by reading the color of colonies selected by the user. For CHROMagar orientation, Biomic results agreed with conventional methods for 94% of the strains assayed. For CHROMagar MRSA, Biomic correctly identified 100% of the strains tested and did not misidentify two methicillin-susceptible Staphylococcus aureus strains growing on the plates. PMID:18701661
Mechanisms of Selective Attention in Generalized Anxiety Disorder
Yiend, Jenny; Mathews, Andrew; Burns, Tom; Dutton, Kevin; Fernández-Martín, Andrés; Georgiou, George A.; Luckie, Michael; Rose, Alexandra; Russo, Riccardo; Fox, Elaine
2015-01-01
A well-established literature has identified different selective attentional orienting mechanisms underlying anxiety-related attentional bias, such as engagement and disengagement of attention. These mechanisms are thought to contribute to the onset and maintenance of anxiety disorders. However, conclusions to date have relied heavily on experimental work from subclinical samples. We therefore investigated individuals with diagnosed generalized anxiety disorder (GAD), healthy volunteers, and individuals with high trait anxiety (but not meeting GAD diagnostic criteria). Across two experiments we found faster disengagement from negative (angry and fearful) faces in GAD groups, an effect opposite to that expected on the basis of the subclinical literature. Together these data challenge current assumptions that we can generalize, to those with GAD, the pattern of selective attentional orienting to threat found in subclinical groups. We suggest a decisive two-stage experiment identifying stimuli of primary salience in GAD, then using these to reexamine orienting mechanisms across groups. PMID:26504675
Horak, Fay B
2006-09-01
Postural control is no longer considered simply a summation of static reflexes but, rather, a complex skill based on the interaction of dynamic sensorimotor processes. The two main functional goals of postural behaviour are postural orientation and postural equilibrium. Postural orientation involves the active alignment of the trunk and head with respect to gravity, support surfaces, the visual surround and internal references. Sensory information from somatosensory, vestibular and visual systems is integrated, and the relative weights placed on each of these inputs are dependent on the goals of the movement task and the environmental context. Postural equilibrium involves the coordination of movement strategies to stabilise the centre of body mass during both self-initiated and externally triggered disturbances of stability. The specific response strategy selected depends not only on the characteristics of the external postural displacement but also on the individual's expectations, goals and prior experience. Anticipatory postural adjustments, prior to voluntary limb movement, serve to maintain postural stability by compensating for destabilising forces associated with moving a limb. The amount of cognitive processing required for postural control depends both on the complexity of the postural task and on the capability of the subject's postural control system. The control of posture involves many different underlying physiological systems that can be affected by pathology or sub-clinical constraints. Damage to any of the underlying systems will result in different, context-specific instabilities. The effective rehabilitation of balance to improve mobility and to prevent falls requires a better understanding of the multiple mechanisms underlying postural control.
Representation of Gravity-Aligned Scene Structure in Ventral Pathway Visual Cortex.
Vaziri, Siavash; Connor, Charles E
2016-03-21
The ventral visual pathway in humans and non-human primates is known to represent object information, including shape and identity [1]. Here, we show the ventral pathway also represents scene structure aligned with the gravitational reference frame in which objects move and interact. We analyzed shape tuning of recently described macaque monkey ventral pathway neurons that prefer scene-like stimuli to objects [2]. Individual neurons did not respond to a single shape class, but to a variety of scene elements that are typically aligned with gravity: large planes in the orientation range of ground surfaces under natural viewing conditions, planes in the orientation range of ceilings, and extended convex and concave edges in the orientation range of wall/floor/ceiling junctions. For a given neuron, these elements tended to share a common alignment in eye-centered coordinates. Thus, each neuron integrated information about multiple gravity-aligned structures as they would be seen from a specific eye and head orientation. This eclectic coding strategy provides only ambiguous information about individual structures but explicit information about the environmental reference frame and the orientation of gravity in egocentric coordinates. In the ventral pathway, this could support perceiving and/or predicting physical events involving objects subject to gravity, recognizing object attributes like animacy based on movement not caused by gravity, and/or stabilizing perception of the world against changes in head orientation [3-5]. Our results, like the recent discovery of object weight representation [6], imply that the ventral pathway is involved not just in recognition, but also in physical understanding of objects and scenes. Copyright © 2016 Elsevier Ltd. All rights reserved.
Sexual Orientation Disparities in Purging and Binge Eating From Early to Late Adolescence
Austin, S. Bryn; Ziyadeh, Najat J.; Corliss, Heather L.; Rosario, Margaret; Wypij, David; Haines, Jess; Camargo, Carlos A.; Field, Alison E.
2009-01-01
Purpose To describe patterns of purging and binge eating from early through late adolescence in female and male youth across a range of sexual orientations. Methods Using data from the prospective Growing Up Today Study, a large cohort of U.S. youth, we investigated trends in past-year self-reports of purging (ever vomit or use laxatives for weight control) and binge eating at least monthly. The analytic sample included 57,668 observations from repeated measures gathered from 13,795 youth ages 12 to 23 years providing information collected by self-administered questionnaires from six waves of data collection. We used multivariable logistic regression models to examine sexual orientation group (heterosexual, “mostly heterosexual,” bisexual, and lesbian/gay) differences in purging and binge eating throughout adolescence, with same-gender heterosexuals as the referent group and controlling for age and race/ethnicity. Results Throughout adolescence, in most cases, sexual orientation group differences were evident at the youngest ages and persisted through adolescence. Among females and compared to heterosexuals, “mostly heterosexuals,” bisexuals, and lesbians were more likely to report binge eating, but only “mostly heterosexuals” and bisexuals were also more likely to report purging. Among males, all three sexual orientation subgroups were more likely than heterosexual males to report both binge eating and purging. Within each orientation subgroup, females generally reported higher prevalence of purging and binge eating than did males. Conclusions Clinicians need to be alert to the risk of eating disordered behaviors in lesbian, gay, bisexual, and “mostly heterosexual” adolescents of both genders in order to better evaluate these youth and refer them for treatment. PMID:19699419
Bahadori, Mohammadkarim; Yaghoubi, Maryam; Javadi, Marzieh; Rahimi, Zahreh Agha
2015-01-01
Considering globalization of health care and quality improvement trend to respond to competition and customer orientation, attention to organizational structure and its relationship with market orientation is essential. Therefore, this study reviews the relationship between organizational structure and market orientation in selected hospitals of Isfahan (Iran). This study was a descriptive survey. The study population comprised nurse managers from selected hospitals (n = 80). Data collection tools were two questionnaires (market orientation questionnaire and organizational structure) that the validity and reliability were confirmed (r = 0.83 for market orientation questionnaire and r = 0.87 for organizational structure). SPSS (Ver. 16) software was used for the analyses. The mean score of organizational structure was 65.4 (11.2) and total mean of market orientation was 51.14 (17.6). All aspects of the organizational structure (Organization Centralization, Formalization in Organization, and Organization Complication) and market orientation (responding to competition, accountability, customer satisfaction, intelligent organization)-except by responding to clients with Formalization in Organization-as well as all aspects of the Systemic attitude (the system of internal coordination and communication systems_ and market orientation (responding to competition, accountability, customer satisfaction, intelligent organization), there was a meaningful relationship (P < 0.05). Market orientation and its dimensions have a significant relationship with organizational structure and can lead managers' view to the analysis and recognizing elements of success and achievement to goals. With increasing competition in markets, globalization of health services, and presence in international markets and more attention to patients' satisfaction, hospitals need to understand and use of market orientation in order to promote quality and services in the health care system.
McDonald, J Scott; Seymour, Kiley J; Schira, Mark M; Spehar, Branka; Clifford, Colin W G
2009-05-01
The responses of orientation-selective neurons in primate visual cortex can be profoundly affected by the presence and orientation of stimuli falling outside the classical receptive field. Our perception of the orientation of a line or grating also depends upon the context in which it is presented. For example, the perceived orientation of a grating embedded in a surround tends to be repelled from the predominant orientation of the surround. Here, we used fMRI to investigate the basis of orientation-specific surround effects in five functionally-defined regions of visual cortex: V1, V2, V3, V3A/LO1 and hV4. Test stimuli were luminance-modulated and isoluminant gratings that produced responses similar in magnitude. Less BOLD activation was evident in response to gratings with parallel versus orthogonal surrounds across all the regions of visual cortex investigated. When an isoluminant test grating was surrounded by a luminance-modulated inducer, the degree of orientation-specific contextual modulation was no larger for extrastriate areas than for V1, suggesting that the observed effects might originate entirely in V1. However, more orientation-specific modulation was evident in extrastriate cortex when both test and inducer were luminance-modulated gratings than when the test was isoluminant; this difference was significant in area V3. We suggest that the pattern of results in extrastriate cortex may reflect a refinement of the orientation-selectivity of surround suppression specific to the colour of the surround or, alternatively, processes underlying the segmentation of test and inducer by spatial phase or orientation when no colour cue is available.
Bahadori, Mohammadkarim; Yaghoubi, Maryam; Javadi, Marzieh; Rahimi, Zahreh Agha
2015-01-01
Background: Considering globalization of health care and quality improvement trend to respond to competition and customer orientation, attention to organizational structure and its relationship with market orientation is essential. Therefore, this study reviews the relationship between organizational structure and market orientation in selected hospitals of Isfahan (Iran). Materials and Methods: This study was a descriptive survey. The study population comprised nurse managers from selected hospitals (n = 80). Data collection tools were two questionnaires (market orientation questionnaire and organizational structure) that the validity and reliability were confirmed (r = 0.83 for market orientation questionnaire and r = 0.87 for organizational structure). SPSS (Ver. 16) software was used for the analyses. Results: The mean score of organizational structure was 65.4 (11.2) and total mean of market orientation was 51.14 (17.6). All aspects of the organizational structure (Organization Centralization, Formalization in Organization, and Organization Complication) and market orientation (responding to competition, accountability, customer satisfaction, intelligent organization)—except by responding to clients with Formalization in Organization—as well as all aspects of the Systemic attitude (the system of internal coordination and communication systems_ and market orientation (responding to competition, accountability, customer satisfaction, intelligent organization), there was a meaningful relationship (P < 0.05). Conclusion: Market orientation and its dimensions have a significant relationship with organizational structure and can lead managers’ view to the analysis and recognizing elements of success and achievement to goals. With increasing competition in markets, globalization of health services, and presence in international markets and more attention to patients’ satisfaction, hospitals need to understand and use of market orientation in order to promote quality and services in the health care system. PMID:25861660
A test of the hypothesis that correlational selection generates genetic correlations.
Roff, Derek A; Fairbairn, Daphne J
2012-09-01
Theory predicts that correlational selection on two traits will cause the major axis of the bivariate G matrix to orient itself in the same direction as the correlational selection gradient. Two testable predictions follow from this: for a given pair of traits, (1) the sign of correlational selection gradient should be the same as that of the genetic correlation, and (2) the correlational selection gradient should be positively correlated with the value of the genetic correlation. We test this hypothesis with a meta-analysis utilizing empirical estimates of correlational selection gradients and measures of the correlation between the two focal traits. Our results are consistent with both predictions and hence support the underlying hypothesis that correlational selection generates a genetic correlation between the two traits and hence orients the bivariate G matrix. © 2012 The Author(s). Evolution© 2012 The Society for the Study of Evolution.
Advances in 6d diffraction contrast tomography
NASA Astrophysics Data System (ADS)
Viganò, N.; Ludwig, W.
2018-04-01
The ability to measure 3D orientation fields and to determine grain boundary character plays a key role in understanding many material science processes, including: crack formation and propagation, grain coarsening, and corrosion processes. X-ray diffraction imaging techniques offer the ability to retrieve such information in a non-destructive manner. Among them, Diffraction Contrast Tomography (DCT) is a monochromatic beam, near-field technique, that uses an extended beam and offers fast mapping of 3D sample volumes. It was previously shown that the six-dimensional extension of DCT can be applied to moderately deformed samples (<= 5% total strain), made from materials that exhibit low levels of elastic deformation of the unit cell (<= 1%). In this article, we improved over the previously proposed 6D-DCT reconstruction method, through the introduction of both a more advanced forward model and reconstruction algorithm. The results obtained with the proposed improvements are compared against the reconstructions previously published in [1], using Electron Backscatter Diffraction (EBSD) measurements as a reference. The result was a noticeably higher quality reconstruction of the grain boundary positions and local orientation fields. The achieved reconstruction quality, together with the low acquisition times, render DCT a valuable tool for the stop-motion study of polycrystalline microstructures, evolving as a function of applied strain or thermal annealing treatments, for selected materials.
Ioriatti, Claudio; Anfora, Gianfranco; Angeli, Gino; Civolani, Stefano; Schmidt, Silvia; Pasqualini, Edison
2009-03-01
Emamectin benzoate is a novel macrocyclic lactone insecticide derived from naturally occurring avermectin molecules isolated by fermentation from the soil microorganism Streptomyces avermitilis Kim & Goodfellow. The present study aims to evaluate the toxicity of emamectin benzoate to codling moth, Cydia pomonella (L.), and oriental fruit moth, C. molesta (Busck), under laboratory and semi-field conditions. Dose response bioassays showed that emamectin benzoate had a high level of intrinsic toxicity to early-stage larvae of both species, and that contact activity might contribute significantly to mortality. In the semi-field trials, residual toxicity lasted for more than 1 week. Ovicidal activity was recorded only for C. pomonella (approximately 30%), irrespective of the concentrations tested. Field trials confirmed the efficacy of emamectin benzoate on codling moth when applied at 7 day intervals. Fruit damage, both from the first and second generations, was comparable with that on treatment with chlorpyrifos-ethyl, used as a chemical reference. Emamectin benzoate may be considered a valuable tool for the control of codling moth as a component of an IPM programme. Its collective advantages are: high efficacy, lack of cross-resistance with currently used products, control of secondary pests such as oriental fruit moth and selective toxicity that spares beneficials. 2008 Society of Chemical Industry
Mapping number to space in the two hemispheres of the avian brain.
Rugani, Rosa; Vallortigara, Giorgio; Regolin, Lucia
2016-09-01
Pre-verbal infants and non-human animals associate small numbers with the left space and large numbers with the right space. Birds and primates, trained to identify a given position in a sagittal series of identical positions, whenever required to respond on a left/right oriented series, referred the given position starting from the left end. Here, we extended this evidence by selectively investigating the role of either cerebral hemisphere, using the temporary monocular occlusion technique. In birds, lacking the corpus callosum, visual input is fed mainly to the contralateral hemisphere. We trained 4-day-old chicks to identify the 4th element in a sagittal series of 10 identical elements. At test, the series was identical but left/right oriented. Test was conducted in right monocular, left monocular or binocular condition of vision. Right monocular chicks pecked at the 4th right element; left monocular and binocular chicks pecked at the 4th left element. Data on monocular chicks demonstrate that both hemispheres deal with an ordinal (sequential) task. Data on binocular chicks indicate that the left bias is linked to a right hemisphere dominance, that allocates the attention toward the left hemispace. This constitutes a first step towards understanding the neural basis of number space mapping. Copyright © 2016 Elsevier Inc. All rights reserved.
A comparative study of six European databases of medically oriented Web resources.
Abad García, Francisca; González Teruel, Aurora; Bayo Calduch, Patricia; de Ramón Frias, Rosa; Castillo Blasco, Lourdes
2005-10-01
The paper describes six European medically oriented databases of Web resources, pertaining to five quality-controlled subject gateways, and compares their performance. The characteristics, coverage, procedure for selecting Web resources, record structure, searching possibilities, and existence of user assistance were described for each database. Performance indicators for each database were obtained by means of searches carried out using the key words, "myocardial infarction." Most of the databases originated in the 1990s in an academic or library context and include all types of Web resources of an international nature. Five databases use Medical Subject Headings. The number of fields per record varies between three and nineteen. The language of the search interfaces is mostly English, and some of them allow searches in other languages. In some databases, the search can be extended to Pubmed. Organizing Medical Networked Information, Catalogue et Index des Sites Médicaux Francophones, and Diseases, Disorders and Related Topics produced the best results. The usefulness of these databases as quick reference resources is clear. In addition, their lack of content overlap means that, for the user, they complement each other. Their continued survival faces three challenges: the instability of the Internet, maintenance costs, and lack of use in spite of their potential usefulness.
Bergamini, Elena; Ligorio, Gabriele; Summa, Aurora; Vannozzi, Giuseppe; Cappozzo, Aurelio; Sabatini, Angelo Maria
2014-10-09
Magnetic and inertial measurement units are an emerging technology to obtain 3D orientation of body segments in human movement analysis. In this respect, sensor fusion is used to limit the drift errors resulting from the gyroscope data integration by exploiting accelerometer and magnetic aiding sensors. The present study aims at investigating the effectiveness of sensor fusion methods under different experimental conditions. Manual and locomotion tasks, differing in time duration, measurement volume, presence/absence of static phases, and out-of-plane movements, were performed by six subjects, and recorded by one unit located on the forearm or the lower trunk, respectively. Two sensor fusion methods, representative of the stochastic (Extended Kalman Filter) and complementary (Non-linear observer) filtering, were selected, and their accuracy was assessed in terms of attitude (pitch and roll angles) and heading (yaw angle) errors using stereophotogrammetric data as a reference. The sensor fusion approaches provided significantly more accurate results than gyroscope data integration. Accuracy improved mostly for heading and when the movement exhibited stationary phases, evenly distributed 3D rotations, it occurred in a small volume, and its duration was greater than approximately 20 s. These results were independent from the specific sensor fusion method used. Practice guidelines for improving the outcome accuracy are provided.
How do reference montage and electrodes setup affect the measured scalp EEG potentials?
NASA Astrophysics Data System (ADS)
Hu, Shiang; Lai, Yongxiu; Valdes-Sosa, Pedro A.; Bringas-Vega, Maria L.; Yao, Dezhong
2018-04-01
Objective. Human scalp electroencephalogram (EEG) is widely applied in cognitive neuroscience and clinical studies due to its non-invasiveness and ultra-high time resolution. However, the representativeness of the measured EEG potentials for the underneath neural activities is still a problem under debate. This study aims to investigate systematically how both reference montage and electrodes setup affect the accuracy of EEG potentials. Approach. First, the standard EEG potentials are generated by the forward calculation with a single dipole in the neural source space, for eleven channel numbers (10, 16, 21, 32, 64, 85, 96, 128, 129, 257, 335). Here, the reference is the ideal infinity implicitly determined by forward theory. Then, the standard EEG potentials are transformed to recordings with different references including five mono-polar references (Left earlobe, Fz, Pz, Oz, Cz), and three re-references (linked mastoids (LM), average reference (AR) and reference electrode standardization technique (REST)). Finally, the relative errors between the standard EEG potentials and the transformed ones are evaluated in terms of channel number, scalp regions, electrodes layout, dipole source position and orientation, as well as sensor noise and head model. Main results. Mono-polar reference recordings are usually of large distortions; thus, a re-reference after online mono-polar recording should be adopted in general to mitigate this effect. Among the three re-references, REST is generally superior to AR for all factors compared, and LM performs worst. REST is insensitive to head model perturbation. AR is subject to electrodes coverage and dipole orientation but no close relation with channel number. Significance. These results indicate that REST would be the first choice of re-reference and AR may be an alternative option for high level sensor noise case. Our findings may provide the helpful suggestions on how to obtain the EEG potentials as accurately as possible for cognitive neuroscientists and clinicians.
Living in the Past, Present, and Future: Measuring Temporal Orientation With Language.
Park, Gregory; Schwartz, H Andrew; Sap, Maarten; Kern, Margaret L; Weingarten, Evan; Eichstaedt, Johannes C; Berger, Jonah; Stillwell, David J; Kosinski, Michal; Ungar, Lyle H; Seligman, Martin E P
2017-04-01
Temporal orientation refers to individual differences in the relative emphasis one places on the past, present, or future, and it is related to academic, financial, and health outcomes. We propose and evaluate a method for automatically measuring temporal orientation through language expressed on social media. Judges rated the temporal orientation of 4,302 social media messages. We trained a classifier based on these ratings, which could accurately predict the temporal orientation of new messages in a separate validation set (accuracy/mean sensitivity = .72; mean specificity = .77). We used the classifier to automatically classify 1.3 million messages written by 5,372 participants (50% female; ages 13-48). Finally, we tested whether individual differences in past, present, and future orientation differentially related to gender, age, Big Five personality, satisfaction with life, and depressive symptoms. Temporal orientations exhibit several expected correlations with age, gender, and Big Five personality. More future-oriented people were older, more likely to be female, more conscientious, less impulsive, less depressed, and more satisfied with life; present orientation showed the opposite pattern. Language-based assessments can complement and extend existing measures of temporal orientation, providing an alternative approach and additional insights into language and personality relationships. © 2015 Wiley Periodicals, Inc.
ERIC Educational Resources Information Center
Lysander, Katya; Horton, William S.
2012-01-01
Many communicative situations present interlocutors with the opportunity to use multiple modalities to establish shared perspectives on conversational referents, a process known as grounding. In the current study, we use a card-matching task to examine how conversational grounding in younger and older adults is influenced both by direct visual…
ERIC Educational Resources Information Center
Shapero, Joshua A.
2017-01-01
Previous studies have shown that language contributes to humans' ability to orient using landmarks and shapes their use of frames of reference (FoRs) for memory. However, the role of environmental experience in shaping spatial cognition has not been investigated. This study addresses such a possibility by examining the use of FoRs in a nonverbal…
Orientation selectivity in a multi-gated organic electrochemical transistor
NASA Astrophysics Data System (ADS)
Gkoupidenis, Paschalis; Koutsouras, Dimitrios A.; Lonjaret, Thomas; Fairfield, Jessamyn A.; Malliaras, George G.
2016-06-01
Neuromorphic devices offer promising computational paradigms that transcend the limitations of conventional technologies. A prominent example, inspired by the workings of the brain, is spatiotemporal information processing. Here we demonstrate orientation selectivity, a spatiotemporal processing function of the visual cortex, using a poly(3,4ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) organic electrochemical transistor with multiple gates. Spatially distributed inputs on a gate electrode array are found to correlate with the output of the transistor, leading to the ability to discriminate between different stimuli orientations. The demonstration of spatiotemporal processing in an organic electronic device paves the way for neuromorphic devices with new form factors and a facile interface with biology.
Rigorous Combination of GNSS and VLBI: How it Improves Earth Orientation and Reference Frames
NASA Astrophysics Data System (ADS)
Lambert, S. B.; Richard, J. Y.; Bizouard, C.; Becker, O.
2017-12-01
Current reference series (C04) of the International Earth Rotation and Reference Systems Service (IERS) are produced by a weighted combination of Earth orientation parameters (EOP) time series built up by combination centers of each technique (VLBI, GNSS, Laser ranging, DORIS). In the future, we plan to derive EOP from a rigorous combination of the normal equation systems of the four techniques.We present here the results of a rigorous combination of VLBI and GNSS pre-reduced, constraint-free, normal equations with the DYNAMO geodetic analysis software package developed and maintained by the French GRGS (Groupe de Recherche en GeÌodeÌsie Spatiale). The used normal equations are those produced separately by the IVS and IGS combination centers to which we apply our own minimal constraints.We address the usefulness of such a method with respect to the classical, a posteriori, combination method, and we show whether EOP determinations are improved.Especially, we implement external validations of the EOP series based on comparison with geophysical excitation and examination of the covariance matrices. Finally, we address the potential of the technique for the next generation celestial reference frames, which are currently determined by VLBI only.
Multiple reference frames in haptic spatial processing
NASA Astrophysics Data System (ADS)
Volčič, R.
2008-08-01
The present thesis focused on haptic spatial processing. In particular, our interest was directed to the perception of spatial relations with the main focus on the perception of orientation. To this end, we studied haptic perception in different tasks, either in isolation or in combination with vision. The parallelity task, where participants have to match the orientations of two spatially separated bars, was used in its two-dimensional and three-dimensional versions in Chapter 2 and Chapter 3, respectively. The influence of non-informative vision and visual interference on performance in the parallelity task was studied in Chapter 4. A different task, the mental rotation task, was introduced in a purely haptic study in Chapter 5 and in a visuo-haptic cross-modal study in Chapter 6. The interaction of multiple reference frames and their influence on haptic spatial processing were the common denominators of these studies. In this thesis we approached the problems of which reference frames play the major role in haptic spatial processing and how the relative roles of distinct reference frames change depending on the available information and the constraints imposed by different tasks. We found that the influence of a reference frame centered on the hand was the major cause of the deviations from veridicality observed in both the two-dimensional and three-dimensional studies. The results were described by a weighted average model, in which the hand-centered egocentric reference frame is supposed to have a biasing influence on the allocentric reference frame. Performance in haptic spatial processing has been shown to depend also on sources of information or processing that are not strictly connected to the task at hand. When non-informative vision was provided, a beneficial effect was observed in the haptic performance. This improvement was interpreted as a shift from the egocentric to the allocentric reference frame. Moreover, interfering visual information presented in the vicinity of the haptic stimuli parametrically modulated the magnitude of the deviations. The influence of the hand-centered reference frame was shown also in the haptic mental rotation task where participants were quicker in judging the parity of objects when these were aligned with respect to the hands than when they were physically aligned. Similarly, in the visuo-haptic cross-modal mental rotation task the parity judgments were influenced by the orientation of the exploring hand with respect to the viewing direction. This effect was shown to be modulated also by an intervening temporal delay that supposedly counteracts the influence of the hand-centered reference frame. We suggest that the hand-centered reference frame is embedded in a hierarchical structure of reference frames where some of these emerge depending on the demands and the circumstances of the surrounding environment and the needs of an active perceiver.
Ariz-Extreme, Igor; Hub, Jochen S
2017-02-23
Membrane channels facilitate the efficient and selective flux of various solutes across biological membranes. A common approach to investigate the selectivity of a channel has been the calculation of potentials of mean force (PMFs) for solute permeation across the pore. PMFs have been frequently computed from molecular dynamics (MD) simulations, yet the three-dimensional reference interaction site model (3D-RISM) has been suggested as a computationally efficient alternative to MD. Whether the two methods yield comparable PMFs for solute permeation has remained unclear. In this study, we calculated potentials of mean force for water, ammonia, urea, molecular oxygen, and methanol across the urea transporter B (UT-B) and aquaporin-1 (AQP1), using 3D-RISM, as well as using MD simulations and umbrella sampling. To allow direct comparison between the PMFs from 3D-RISM and MD, we ensure that all PMFs refer to a well-defined reference area in the bulk or, equivalently, to a well-defined density of channels in the membrane. For PMFs of water permeation, we found reasonable agreement between the two methods, with differences of ≲3 kJ mol -1 . In contrast, we found stark discrepancies for the PMFs for all other solutes. Additional calculations confirm that discrepancies between MD and 3D-RISM are not explained by the choice for the closure relation, the definition the reaction coordinate (center of mass-based versus atomic site-based), details of the molecule force field, or fluctuations of the protein. Comparison of the PMFs suggests that 3D-RISM may underestimate effects from hydrophobic solute-channel interactions, thereby, for instance, missing the urea binding sites in UT-B. Furthermore, we speculate that the orientational averages inherent to 3D-RISM might lead to discrepancies in the narrow channel lumen. These findings suggest that current 3D-RISM solvers provide reasonable estimates for the PMF for water permeation, but that they are not suitable to study the selectivity of membrane channels with respect to uncharged nonwater solutes.
Trainable multiscript orientation detection
NASA Astrophysics Data System (ADS)
Van Beusekom, Joost; Rangoni, Yves; Breuel, Thomas M.
2010-01-01
Detecting the correct orientation of document images is an important step in large scale digitization processes, as most subsequent document analysis and optical character recognition methods assume upright position of the document page. Many methods have been proposed to solve the problem, most of which base on ascender to descender ratio computation. Unfortunately, this cannot be used for scripts having no descenders nor ascenders. Therefore, we present a trainable method using character similarity to compute the correct orientation. A connected component based distance measure is computed to compare the characters of the document image to characters whose orientation is known. This allows to detect the orientation for which the distance is lowest as the correct orientation. Training is easily achieved by exchanging the reference characters by characters of the script to be analyzed. Evaluation of the proposed approach showed accuracy of above 99% for Latin and Japanese script from the public UW-III and UW-II datasets. An accuracy of 98.9% was obtained for Fraktur on a non-public dataset. Comparison of the proposed method to two methods using ascender / descender ratio based orientation detection shows a significant improvement.
The surface orientation of some Apollo 14 rocks.
NASA Technical Reports Server (NTRS)
Hoerz, F.; Morrison, D. A.; Hartung, J. B.
1972-01-01
Detailed stereomicroscopic studies of the distribution of microcraters, soil covers, and glass coatings were performed to reconstruct the most recent surface orientations of selected Apollo 14 rocks. Surface orientations could be established for rocks 14053, 14073, 14301, 14303, 14307, 14310, and 14311 (which includes rock 14308). A tentative orientation of rock 14055 is suggested, and comments concerning the surface history of rocks 14302, 14305, and 14318 are presented. The examination of rocks 14066, 14306, and 14321 indicates that these specimens have complicated surface histories that prevent reconstruction of their orientation by the criteria that were established in these stereomicroscopic studies.
A variational approach to dynamics of flexible multibody systems
NASA Technical Reports Server (NTRS)
Wu, Shih-Chin; Haug, Edward J.; Kim, Sung-Soo
1989-01-01
This paper presents a variational formulation of constrained dynamics of flexible multibody systems, using a vector-variational calculus approach. Body reference frames are used to define global position and orientation of individual bodies in the system, located and oriented by position of its origin and Euler parameters, respectively. Small strain linear elastic deformation of individual components, relative to their body references frames, is defined by linear combinations of deformation modes that are induced by constraint reaction forces and normal modes of vibration. A library of kinematic couplings between flexible and/or rigid bodies is defined and analyzed. Variational equations of motion for multibody systems are obtained and reduced to mixed differential-algebraic equations of motion. A space structure that must deform during deployment is analyzed, to illustrate use of the methods developed.
Residual effects of ecstasy (3,4-methylenedioxymethamphetamine) on low level visual processes.
Murray, Elizabeth; Bruno, Raimondo; Brown, John
2012-03-01
'Ecstasy' (3,4-methylenedioxymethamphetamine) induces impaired functioning in the serotonergic system, including the occipital lobe. This study employed the 'tilt aftereffect' paradigm to operationalise the function of orientation-selective neurons among ecstasy consumers and controls as a means of investigating the role of reduced serotonin on visual orientation processing. The magnitude of the tilt aftereffect reflects the extent of lateral inhibition between orientation-selective neurons and is elicited to both 'real' contours, processed in visual cortex area V1, and illusory contours, processed in V2. The magnitude of tilt aftereffect to both contour types was examined among 19 ecstasy users (6 ecstasy only; 13 ecstasy-plus-cannabis users) and 23 matched controls (9 cannabis-only users; 14 drug-naive). Ecstasy users had a significantly greater tilt magnitude than non-users for real contours (Hedge's g = 0.63) but not for illusory contours (g = 0.20). These findings provide support for literature suggesting that residual effects of ecstasy (and reduced serotonin) impairs lateral inhibition between orientation-selective neurons in V1, which however suggests that ecstasy may not substantially affect this process in V2. Multiple studies have now demonstrated ecstasy-related deficits on basic visual functions, including orientation and motion processing. Such low-level effects may contribute to the impact of ecstasy use on neuropsychological tests of visuospatial function. Copyright © 2012 John Wiley & Sons, Ltd.
Perez-Felkner, Lara; McDonald, Sarah-Kathryn; Schneider, Barbara; Grogan, Erin
2012-11-01
Although important strides toward gender parity have been made in several scientific fields, women remain underrepresented in the physical sciences, engineering, mathematics, and computer sciences (PEMCs). This study examines the effects of adolescents' subjective orientations, course taking, and academic performance on the likelihood of majoring in PEMC in college. Results indicate that racial-ethnic and gender underrepresentation in science, technology, engineering, and mathematics (STEM) fields are interrelated and should be examined with attention to the intersecting factors influencing female and racial-ethnic minority adolescents' pathways toward careers in these fields. Among those who major in PEMC fields, women closely resemble men with respect to their subjective orientations. The effects of subjective orientations on women's chances of majoring in PEMC vary by their secondary school mathematics course completion levels. Women who take more mathematics courses are more likely to major in PEMC; however, course taking alone does not attenuate gender disparities in declaring these majors. High mathematics ability (as measured by standardized test scores in the 10th grade) appears to be positively associated with women's selection of social, behavioral, clinical, and health science majors. This association is less robust (and slightly negative) for women in PEMC. While advanced course taking appears to assist women in selecting PEMC majors, women who enter these fields may not be as strong as those who select other, less male-dominated scientific fields.
GetData: A filesystem-based, column-oriented database format for time-ordered binary data
NASA Astrophysics Data System (ADS)
Wiebe, Donald V.; Netterfield, Calvin B.; Kisner, Theodore S.
2015-12-01
The GetData Project is the reference implementation of the Dirfile Standards, a filesystem-based, column-oriented database format for time-ordered binary data. Dirfiles provide a fast, simple format for storing and reading data, suitable for both quicklook and analysis pipelines. GetData provides a C API and bindings exist for various other languages. GetData is distributed under the terms of the GNU Lesser General Public License.
Gender Bias in Leader Selection.
ERIC Educational Resources Information Center
Teaching of Psychology, 1995
1995-01-01
Describes a classroom exercise showing students how stereotypes can result in sex-biased leader selection. Finds that task-oriented competitive instructions produce a disproportionate number of selected male leaders. Includes procedures for replicating and evaluating the exercise. (CFR)
Poch, Claudia; Campo, Pablo; Barnes, Gareth R
2014-07-01
Selective attention mechanisms allow us to focus on information that is relevant to the current behavior and, equally important, ignore irrelevant information. An influential model proposes that oscillatory neural activity in the alpha band serves as an active functional inhibitory mechanism. Recent studies have shown that, in the same way that attention can be selectively oriented to bias sensory processing in favor of relevant stimuli in perceptual tasks, it is also possible to retrospectively orient attention to internal representations held in working memory. However, these studies have not explored the associated oscillatory phenomena. In the current study, we analysed the patterns of neural oscillatory activity recorded with magnetoencephalography while participants performed a change detection task, in which a spatial retro-cue was presented during the maintenance period, indicating which item or items were relevant for subsequent retrieval. Participants benefited from retro-cues in terms of accuracy and reaction time. Retro-cues also modulated oscillatory activity in the alpha and gamma frequency bands. We observed greater alpha activity in a ventral visual region ipsilateral to the attended hemifield, thus supporting its suppressive role, i.e., a functional disengagement of task-irrelevant regions. Accompanying this modulation, we found an increase in gamma activity contralateral to the attended hemifield, which could reflect attentional orienting and selective processing. These findings suggest that the oscillatory mechanisms underlying attentional orienting to representations held in working memory are similar to those engaged when attention is oriented in the perceptual space. © 2014 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd.
Ingleby, S J; Griffin, P F; Arnold, A S; Chouliara, M; Riis, E
2017-04-01
An integrated system of hardware and software allowing precise definition of arbitrarily oriented magnetic fields up to |B| = 1 μT within a five-layer Mumetal shield is described. The system is calibrated with reference to magnetic resonance observed between Zeeman states of the 6S 1/2 F = 4 133 Cs ground state. Magnetic field definition over the full 4π solid angle is demonstrated with one-sigma tolerances in magnitude, orientation, and gradient of δ|B| = 0.94 nT, δθ = 5.9 mrad, and δ|∇B|=13.0 pT/mm, respectively. This field control is used to empirically map M x magnetometer signal amplitude as a function of the static field (B 0 ) orientation.
Tian, Kaiyu; Rao, Hong; Lin, Yongqing; He, Yang; Zhao, Junqing; Chen, Qiang
2017-03-12
Acupuncture with Point Location is one of the mandatory examinations for the Diplomate of Oriental Medicine (Dipl.OM.) or Acupuncture (Dipl. Ac.) by American National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM). In reference to NCCAOM Certification Handbook, Acupuncture with Point Location Expanded Content Outline , and Study Guide for Diplomates in Acupuncture Certification , the authors introduced the examination pattern and examination-related contents including such aspects as safety and professional responsibilities, treatment plan, and point location and discussed additionally the enlightening effects on acupuncture practice and examination in universities and international associations of Chinese medicine in our country.
A Selective Critique of Animal Experiments in Human-Orientated Biological Research.
ERIC Educational Resources Information Center
Webb, G. P.
1990-01-01
The advantages and justifications for using small animals in human-oriented research are reviewed. Some of the pitfalls of extrapolating animal-derived data to humans are discussed. Several specific problems with animal experimentation are highlighted. (CW)
Spatial vision within egocentric and exocentric frames of reference
NASA Technical Reports Server (NTRS)
Howard, Ian P.
1991-01-01
It is remarkable that we are able to perceive a stable visual world and judge the directions, orientations, and movements of visual objects given that images move on the retina, the eyes move in the head, the head moves on the body, and the body moves in space. An understanding of the mechanisms underlying perceptual stability and spatial judgements requires precise definitions of relevant coordinate systems. An egocentric frame of reference is defined with respect to some part of the observer. There are four principal egocentric frames of reference, a station-point frame associated with the nodal point of the eye, an retinocentric frame associated with the retina, a headcentric frame associated with the head, and a bodycentric frame (torsocentric) associated with the torso. Additional egocentric frames can be identified with respect to any segment of the body. An egocentric task is one in which the position, orientation, or motion of an object is judged with respect to an egocentric frame of reference. A proprioceptive is a special kind of egocentric task in which the object being judged is also part of the body. An example of a proprioceptive task is that of directing the gaze toward the seen or unseen toe. An exocentric frame of reference is external to the observer. Geographical coordinates and the direction of gravity are examples of exocentric frames of reference. These various frames are listed in tabular form, together with examples of judgements of each type.
NASA Astrophysics Data System (ADS)
Muluneh, Ameha A.; Cuffaro, Marco; Doglioni, Carlo
2014-09-01
We present the kinematics of the Ethiopian Rift, in the northern part of East African Rift System, derived from compilation of geodetic velocities, focal mechanism inversions, structural data analysis and geological profiles. In the central Ethiopian Rift, the GPS velocity field shows a systematic magnitude increase in ENE direction, and the incremental extensional strain axes recorded by earthquake focal mechanisms and fault slip inversion show ≈ N100°E orientation. This deviation between direction of GPS velocity vectors and orientation of incremental extensional strain is developed due to left lateral transtensional deformation along the NE-SW trending segment of the rift. This interpretation is consistent with the en-échelon pattern of tensional and transtensional faults, plus the distribution of the volcanic centers, and the asymmetry of the rift itself. We analyzed the kinematics of the Ethiopian Rift also relative to the mantle comparing the results in the deep and shallow hotspot reference frames. While the oblique orientation of the rift was controlled by the pre-existing lithospheric fabric, the two reference frames predict different kinematics of Africa and Somalia plates along the rift itself, both in magnitude and direction, and with respect to the mantle. However, the observed kinematics and tectonics along the rift are more consistent with a faster WSW-ward motion of Africa than Somalia observed in the shallow hotspot framework. The faster WSW motion of Africa with respect to Somalia plate is inferred to be due to the lower viscosity in the top asthenosphere (LVZ-low-velocity zone) beneath Africa. These findings have significant implication for the evolution of continental rifting in transtensional settings and provide evidence for the kinematics of the Ethiopian Rift in the context of the Africa-Somalia plate interaction in the mantle reference frame.
ERIC Educational Resources Information Center
Gafoor, Kunnathodi Abdul; Kurukkan, Abidha
2014-01-01
The purpose of the study is to investigate the relation between parenting style and goal orientation among boys and girls in higher secondary schools of Kerala. Four types of parenting style and five categories of goal orientation. The sample comprised of 467 girls and 365 boys from higher secondary school in Kerala who were selected through…
Improved ultrasonic standard reference blocks
NASA Technical Reports Server (NTRS)
Eitzen, D. G.
1975-01-01
A program to improve the quality, reproducibility and reliability of nondestructive testing through the development of improved ASTM-type ultrasonic reference standards is described. Reference blocks of aluminum, steel, and titanium alloys were considered. Equipment representing the state-of-the-art in laboratory and field ultrasonic equipment was obtained and evaluated. Some RF and spectral data on ten sets of ultrasonic reference blocks were taken as part of a task to quantify the variability in response from nominally identical blocks. Techniques for residual stress, preferred orientation, and microstructural measurements were refined and are applied to a reference block rejected by the manufacturer during fabrication in order to evaluate the effect of metallurgical condition on block response.
Tao, X.; Zhang, B.; Smith, E. L.; Nishimoto, S.; Ohzawa, I.
2012-01-01
We used dynamic dense noise stimuli and local spectral reverse correlation methods to reveal the local sensitivities of neurons in visual area 2 (V2) of macaque monkeys to orientation and spatial frequency within their receptive fields. This minimized the potentially confounding assumptions that are inherent in stimulus selections. The majority of neurons exhibited a relatively high degree of homogeneity for the preferred orientations and spatial frequencies in the spatial matrix of facilitatory subfields. However, about 20% of all neurons showed maximum orientation differences between neighboring subfields that were greater than 25 deg. The neurons preferring horizontal or vertical orientations showed less inhomogeneity in space than the neurons preferring oblique orientations. Over 50% of all units also exhibited suppressive profiles, and those were more heterogeneous than facilitatory profiles. The preferred orientation and spatial frequency of suppressive profiles differed substantially from those of facilitatory profiles, and the neurons with suppressive subfields had greater orientation selectivity than those without suppressive subfields. The peak suppression occurred with longer delays than the peak facilitation. These results suggest that the receptive field profiles of the majority of V2 neurons reflect the orderly convergence of V1 inputs over space, but that a subset of V2 neurons exhibit more complex response profiles having both suppressive and facilitatory subfields. These V2 neurons with heterogeneous subfield profiles could play an important role in the initial processing of complex stimulus features. PMID:22114163
Mento, Giovanni
2017-12-01
A main distinction has been proposed between voluntary and automatic mechanisms underlying temporal orienting (TO) of selective attention. Voluntary TO implies the endogenous directing of attention induced by symbolic cues. Conversely, automatic TO is exogenously instantiated by the physical properties of stimuli. A well-known example of automatic TO is sequential effects (SEs), which refer to the adjustments in participants' behavioral performance as a function of the trial-by-trial sequential distribution of the foreperiod between two stimuli. In this study a group of healthy adults underwent a cued reaction time task purposely designed to assess both voluntary and automatic TO. During the task, both post-cue and post-target event-related potentials (ERPs) were recorded by means of a high spatial resolution EEG system. In the results of the post-cue analysis, the P3a and P3b were identified as two distinct ERP markers showing distinguishable spatiotemporal features and reflecting automatic and voluntary a priori expectancy generation, respectively. The brain source reconstruction further revealed that distinct cortical circuits supported these two temporally dissociable components. Namely, the voluntary P3b was supported by a left sensorimotor network, while the automatic P3a was generated by a more distributed frontoparietal circuit. Additionally, post-cue contingent negative variation (CNV) and post-target P3 modulations were observed as common markers of voluntary and automatic expectancy implementation and response selection, although partially dissociable neural networks subserved these two mechanisms. Overall, these results provide new electrophysiological evidence suggesting that distinct neural substrates can be recruited depending on the voluntary or automatic cognitive nature of the cognitive mechanisms subserving TO. Copyright © 2017 Elsevier Ltd. All rights reserved.
Julstrom, Stephen; Kozma-Spytek, Linda; Isabelle, Scott
2011-09-01
In the development of the requirements for telecoil-compatible magnetic signal sources for wireless and cordless telephones to be specified in the American National Standards Institute (ANSI) C63.19 and ANSI/Telecommunications Industry Association-1083 compatibility standards, it became evident that additional data concerning in-the-field telecoil use and subjective preferences were needed. Primarily, the magnetic signal levels and, secondarily, the field orientations required for effective and comfortable telecoil use with wireless and cordless handsets needed further characterization. (A companion article addresses user signal-to-noise needs and preferences.) Test subjects used their own hearing aids, which were addressed with both a controlled acoustic speech source and a controlled magnetic speech source. Each subject's hearing aid was first measured to find the telecoil's magnetic field orientation for maximum response, and an appropriate large magnetic head-worn coil was selected to apply the magnetic signal. Subjects could control the strength of the magnetic signal, first to match the loudness of a reference acoustic signal and then to find their Most Comfortable Level (MCL). The subjective judgments were compared against objective in-ear probe tube level measurements. The 57 test subjects covered an age range of 22 to 79 yr, with a self-reported hearing loss duration of 12 to 72 yr. All had telecoils that they used for at least some telecommunications needs. The self-reported degree of hearing loss ranged from moderate to profound. A total of 69 hearing aids were surveyed for their telecoil orientation. A guided intake questionnaire yielded general background information for each subject. A custom-built test jig enabled hearing aid telecoil orientation within the aid to be determined. By comparing this observation with the in-use hearing aid position, the in-use orientation for each telecoil was determined. A custom-built test control box fed by prepared speech recordings from computer files enabled the tester to switch between acoustic and magnetic speech signals and to read and record the subject's selected magnetic level settings. The overwhelming majority of behind-the-ear aids tested exhibited in-use telecoil orientations that were substantially vertical. An insufficient number of participants used in-the-ear aids to be able to draw general conclusions concerning the telecoil orientations of this style aid. The subjects showed a generally consistent preference for telecoil speech levels that subjectively matched the level that they heard from 65 dB SPL acoustic speech. The magnetic level needed to achieve their MCL, however, varied over a 30 dB range. Producing the necessary magnetic field strengths from a wireless or cordless telephone's handset in an in-use vertical orientation is vital for compatibility with the vast majority of behind-the-ear aids. Due to the very wide range of preferred magnetic signal levels shown, only indirect conclusions can be drawn concerning required signal levels. The strong preference for a 65 dB SPL equivalent level can be combined with established standards addressing hearing aid performance to derive reasonable source level requirements. Greater consistency between in-the-field hearing aid telecoil and microphone sensitivity adjustments could yield improved results for some users. American Academy of Audiology.
Tracking and nowcasting convective precipitation cells at European scale for transregional warnings
NASA Astrophysics Data System (ADS)
Meyer, Vera; Tüchler, Lukas
2013-04-01
A transregional overview of the current weather situation is considered as highly valuable information to assist forecasters as well as official authorities for disaster management in their decision making processes. The development of the European-wide radar composite OPERA enables for the first time a coherent object-oriented tracking and nowcasting of intense precipitation cells in real time at continental scale and at a resolution of 2 x 2 km² and 15 minutes. Recently, the object-oriented cell-tracking tool A-TNT (Austrian Thunderstorm Nowcasting Tool) has been developed at ZAMG. A-TNT utilizes the method of ec-TRAM [1]. It consists of two autonomously operating routines, which identify, track and nowcast radar- and lightning-cells separately. The two independent outputs are combined to a coherent storm monitoring and nowcasting in a final step. Within the framework of HAREN (Hazard Assessment based on Rainfall European Nowcasts), which is a project funded by the EC Directorate General for Humanitarian Aid and Civil Protection, A-TNT has been adapted to OPERA radar data. The objective of HAREN is the support of forecasters and official authorities in their decision-making processes concerning precipitation induced hazards with pan-European information. This study will present (1) the general performance of the object-oriented approach for thunderstorm tracking and nowcasting on continental scale giving insight into its current capabilities and limitations and (2) the utilization of object-oriented cell information for automated precipitation warnings carried out within the framework of HAREN. Data collected from April to October 2012 are used to assess the performance of cell-tracking based on radar data. Furthermore, the benefit of additional lightning information provided by the European Cooperation for Lightning Detection (EUCLID) for thunderstorm tracking and nowcasting will be summarized in selected analyses. REFERENCES: [1] Meyer, V. K., H. Höller, and H. D. Betz 2012: Automated thunderstorm tracking and nowcasting: utilization of three-dimensional lightning and radar data. Manuscript accepted for publication in ACPD.
STS ancillary equipment study. User reference book
NASA Technical Reports Server (NTRS)
Plough, J. A.
1977-01-01
A record of what is currently known about STS ancillary equipment is presented in this user-oriented design so that a potential user may evaluate whether he could use the described ancillary equipment or if he would need to design and fabricate a payload-unique item. References that the user can use to obtain additional details and requirements to aid in his evaluation and decision are included.
ERIC Educational Resources Information Center
Dierdorff, Erich C.; Surface, Eric A.; Brown, Kenneth G.
2010-01-01
Empirical evidence supporting frame-of-reference (FOR) training as an effective intervention for calibrating raters is convincing. Yet very little is known about who does better or worse in FOR training. We conducted a field study of how motivational factors influence affective, cognitive, and behavioral learning outcomes, as well as near transfer…
Spatial and Feature-Based Attention in a Layered Cortical Microcircuit Model
Wagatsuma, Nobuhiko; Potjans, Tobias C.; Diesmann, Markus; Sakai, Ko; Fukai, Tomoki
2013-01-01
Directing attention to the spatial location or the distinguishing feature of a visual object modulates neuronal responses in the visual cortex and the stimulus discriminability of subjects. However, the spatial and feature-based modes of attention differently influence visual processing by changing the tuning properties of neurons. Intriguingly, neurons' tuning curves are modulated similarly across different visual areas under both these modes of attention. Here, we explored the mechanism underlying the effects of these two modes of visual attention on the orientation selectivity of visual cortical neurons. To do this, we developed a layered microcircuit model. This model describes multiple orientation-specific microcircuits sharing their receptive fields and consisting of layers 2/3, 4, 5, and 6. These microcircuits represent a functional grouping of cortical neurons and mutually interact via lateral inhibition and excitatory connections between groups with similar selectivity. The individual microcircuits receive bottom-up visual stimuli and top-down attention in different layers. A crucial assumption of the model is that feature-based attention activates orientation-specific microcircuits for the relevant feature selectively, whereas spatial attention activates all microcircuits homogeneously, irrespective of their orientation selectivity. Consequently, our model simultaneously accounts for the multiplicative scaling of neuronal responses in spatial attention and the additive modulations of orientation tuning curves in feature-based attention, which have been observed widely in various visual cortical areas. Simulations of the model predict contrasting differences between excitatory and inhibitory neurons in the two modes of attentional modulations. Furthermore, the model replicates the modulation of the psychophysical discriminability of visual stimuli in the presence of external noise. Our layered model with a biologically suggested laminar structure describes the basic circuit mechanism underlying the attention-mode specific modulations of neuronal responses and visual perception. PMID:24324628
Keys and seats: Spatial response coding underlying the joint spatial compatibility effect.
Dittrich, Kerstin; Dolk, Thomas; Rothe-Wulf, Annelie; Klauer, Karl Christoph; Prinz, Wolfgang
2013-11-01
Spatial compatibility effects (SCEs) are typically observed when participants have to execute spatially defined responses to nonspatial stimulus features (e.g., the color red or green) that randomly appear to the left and the right. Whereas a spatial correspondence of stimulus and response features facilitates response execution, a noncorrespondence impairs task performance. Interestingly, the SCE is drastically reduced when a single participant responds to one stimulus feature (e.g., green) by operating only one response key (individual go/no-go task), whereas a full-blown SCE is observed when the task is distributed between two participants (joint go/no-go task). This joint SCE (a.k.a. the social Simon effect) has previously been explained by action/task co-representation, whereas alternative accounts ascribe joint SCEs to spatial components inherent in joint go/no-go tasks that allow participants to code their responses spatially. Although increasing evidence supports the idea that spatial rather than social aspects are responsible for joint SCEs emerging, it is still unclear to which component(s) the spatial coding refers to: the spatial orientation of response keys, the spatial orientation of responding agents, or both. By varying the spatial orientation of the responding agents (Exp. 1) and of the response keys (Exp. 2), independent of the spatial orientation of the stimuli, in the present study we found joint SCEs only when both the seating and the response key alignment matched the stimulus alignment. These results provide evidence that spatial response coding refers not only to the response key arrangement, but also to the-often neglected-spatial orientation of the responding agents.
Sensory substitution in bilateral vestibular a-reflexic patients
Alberts, Bart B G T; Selen, Luc P J; Verhagen, Wim I M; Medendorp, W Pieter
2015-01-01
Patients with bilateral vestibular loss have balance problems in darkness, but maintain spatial orientation rather effectively in the light. It has been suggested that these patients compensate for vestibular cues by relying on extravestibular signals, including visual and somatosensory cues, and integrating them with internal beliefs. How this integration comes about is unknown, but recent literature suggests the healthy brain remaps the various signals into a task-dependent reference frame, thereby weighting them according to their reliability. In this paper, we examined this account in six patients with bilateral vestibular a-reflexia, and compared them to six age-matched healthy controls. Subjects had to report the orientation of their body relative to a reference orientation or the orientation of a flashed luminous line relative to the gravitational vertical, by means of a two-alternative-forced-choice response. We tested both groups psychometrically in upright position (0°) and 90° sideways roll tilt. Perception of body tilt was unbiased in both patients and controls. Response variability, which was larger for 90° tilt, did not differ between groups, indicating that body somatosensory cues have tilt-dependent uncertainty. Perception of the visual vertical was unbiased when upright, but showed systematic undercompensation at 90° tilt. Variability, which was larger for 90° tilt than upright, did not differ between patients and controls. Our results suggest that extravestibular signals substitute for vestibular input in patients’ perception of spatial orientation. This is in line with the current status of rehabilitation programs in acute vestibular patients, targeting at recognizing body somatosensory signals as a reliable replacement for vestibular loss. PMID:25975644
Fractal dimension and the navigational information provided by natural scenes.
Shamsyeh Zahedi, Moosarreza; Zeil, Jochen
2018-01-01
Recent work on virtual reality navigation in humans has suggested that navigational success is inversely correlated with the fractal dimension (FD) of artificial scenes. Here we investigate the generality of this claim by analysing the relationship between the fractal dimension of natural insect navigation environments and a quantitative measure of the navigational information content of natural scenes. We show that the fractal dimension of natural scenes is in general inversely proportional to the information they provide to navigating agents on heading direction as measured by the rotational image difference function (rotIDF). The rotIDF determines the precision and accuracy with which the orientation of a reference image can be recovered or maintained and the range over which a gradient descent in image differences will find the minimum of the rotIDF, that is the reference orientation. However, scenes with similar fractal dimension can differ significantly in the depth of the rotIDF, because FD does not discriminate between the orientations of edges, while the rotIDF is mainly affected by edge orientation parallel to the axis of rotation. We present a new equation for the rotIDF relating navigational information to quantifiable image properties such as contrast to show (1) that for any given scene the maximum value of the rotIDF (its depth) is proportional to pixel variance and (2) that FD is inversely proportional to pixel variance. This contrast dependence, together with scene differences in orientation statistics, explains why there is no strict relationship between FD and navigational information. Our experimental data and their numerical analysis corroborate these results.
Potrzebowski, Wojciech; André, Ingemar
2015-07-01
For highly oriented fibrillar molecules, three-dimensional structures can often be determined from X-ray fiber diffraction data. However, because of limited information content, structure determination and validation can be challenging. We demonstrate that automated structure determination of protein fibers can be achieved by guiding the building of macromolecular models with fiber diffraction data. We illustrate the power of our approach by determining the structures of six bacteriophage viruses de novo using fiber diffraction data alone and together with solid-state NMR data. Furthermore, we demonstrate the feasibility of molecular replacement from monomeric and fibrillar templates by solving the structure of a plant virus using homology modeling and protein-protein docking. The generated models explain the experimental data to the same degree as deposited reference structures but with improved structural quality. We also developed a cross-validation method for model selection. The results highlight the power of fiber diffraction data as structural constraints.
Family physicians' interests in special features of electronic publication
Torre, Dario M.; Wright, Scott M.; Wilson, Renee F.; Diener-West, Marie; Bass, Eric B.
2003-01-01
Objective: Because many of the medical journals read by family physicians now have an electronic version, the authors conducted a survey to determine the interest of family physicians in specific features of electronic journal publications. Setting and Participants: We surveyed 175 family physicians randomly selected from the American Academy of Family Physicians. Results: The response rate was 63%. About half of family physicians reported good to excellent computer proficiency, and about one quarter used online journals sometimes or often. Many respondents reported high interest in having links to: an electronic medical text (48% for original articles, 56% for review articles), articles' list of references (52% for original articles, 56% for review articles), and health-related Websites (48% for original and review articles). Conclusion: Primary care–oriented journals should consider the interests of family physicians when developing and offering electronic features for their readers. PMID:12883561
Nelson, Roger
This brief report is a response to the article by Peter Bancel entitled "Searching for Global Consciousness: A Seventeen Year Exploration" in which he compares a goal orientation (GO) model with a field-like model he refers to as global consciousness (GC). He first attempts to exclude the latter, and then presents selected tests that compare the models. While the article appears to provide support for Bancel׳s conclusion that GC cannot explain the data and must be supplanted by GO, there are good reasons to believe this conclusion is premature at best. I address the vulnerable assumptions underlying Bancel׳s rejection of GC, and then provide multiple examples of parametric structure in the data, which cannot be attributed to GO, but are amenable to explanation by field-like models. Copyright © 2017 Elsevier Inc. All rights reserved.
R&D of the CEPC scintillator-tungsten ECAL
NASA Astrophysics Data System (ADS)
Dong, M. Y.
2018-03-01
The circular electron and positron collider (CEPC) was proposed as a future Higgs factory. To meet the physics requirements, a particle flow algorithm-oriented calorimeter system with high energy resolution and precise reconstruction is considered. A sampling calorimeter with scintillator-tungsten sandwich structure is selected as one of the electromagnetic calorimeter (ECAL) options due to its good performance and relatively low cost. We present the design, the test and the optimization of the scintillator module read out by silicon photomultiplier (SiPM), including the design and the development of the electronics. To estimate the performance of the scintillator and SiPM module for particles with different energy, the beam test of a mini detector prototype without tungsten shower material was performed at the E3 beams in Institute of High Energy Physics (IHEP). The results are consistent with the expectation. These studies provide a reference and promote the development of particle flow electromagnetic calorimeter for the CEPC.
A corrosion control manual for rail rapid transit
NASA Technical Reports Server (NTRS)
Gilbert, L. O.; Fitzgerald, J. F., II; Menke, J. T.
1982-01-01
In 1979, during the planning stage of the Metropolitan Dade County Transit System, the need was expressed for a corrosion control manual oriented to urban rapid transit system use. This manual responds to that need. The objective of the manual is to aid rail rapid transit agencies by providing practical solutions to selected corrosion problems. The scope of the manual encompasses corrosion problems of the facilities of rapid transit systems: structures and tracks, platforms and stations, power and signals, and cars. It also discusses stray electric current corrosion. Both design and maintenance solutions are provided for each problem. Also included are descriptions of the types of corrosion and their causes, descriptions of rapid transit properties, a list of corrosion control committees and NASA, DOD, and ASTM specifications and design criteria to which reference is made in the manual. A bibliography of papers and excerpts of reports and a glossary of frequency used terms are provided.
[Between fetishism and survival: are scientific articles a form of academic merchandise?].
Castiel, Luis David; Sanz-Valero, Javier
2007-12-01
This article discusses the possible meanings of the intense prevailing concern in academic circles over the notion of research productivity, as reflected in an excess number of articles published in various scientific journals. The numerical accounting of articles published by researchers in scientific journals with renowned academic status serves to legitimize academics in their fields of work, in various ways. In this sense, we suggest that scientific articles take on aspects of merchandise-as-fetish, according to Marx's theory of use-value and exchange-value and Benjamin's exposure value. Meanwhile, the biological notions of selection and evolution are used as metaphorical elements in "bibliographic Darwinism". There are references as to the possibility many of the prevailing bibliometric concerns serve as instruments for econometric analysis, especially to orient and enhance cost-effectiveness analysis in research investments of various orders and types, from the point of view of their economic return.
The Role of Competition in Word Learning via Referent Selection
ERIC Educational Resources Information Center
Horst, Jessica S.; Scott, Emilly J.; Pollard, Jessica A.
2010-01-01
Previous research suggests that competition among the objects present during referent selection influences young children's ability to learn words in fast mapping tasks. The present study systematically explored this issue with 30-month-old children. Children first received referent selection trials with a target object and either two, three or…
Comparative Study of Nonlinear Time Warping Techniques in Isolated Word Speech Recognition Systems
1981-06-17
all modules are loaded under a flexible research oriented supervisor, " Cicada ". Cicada allows for the integration of experimental ideas, extensions...evaluate alternate recognition methods. More detailed information about Cicada can be found in7 . In the following we limit our discussion to the design of...43.70 37.78 32.47 44.44 44.32 38 8. Figures Cicada - a flexible research oriented supervisor ReferenceSTernpl ates Front End Matching Digital Signal
Viking lander location and spin axis of Mars: determination from radio tracking data.
Michael, W H; Tolson, R H; Mayo, A P; Blackshear, W T; Kelly, G M; Cain, D L; Brenkle, J P; Shapiro, I I; Reasenberg, R D
1976-08-27
Radio tracking data from the Viking lander have been used to determine the lander position and the orientation of the spin axis of Mars. The areocentric coordinates of the lander are 22.27 degrees N, 48.00 degrees W, and 3389.5 kilometers from the center of mass; the spin axis orientation, referred to Earth's mean equator and equinox of 1950.0, is 317.35 degrees right ascension and 52.71 degrees declination.
MDA-based EHR application security services.
Blobel, Bernd; Pharow, Peter
2004-01-01
Component-oriented, distributed, virtual EHR systems have to meet enhanced security and privacy requirements. In the context of advanced architectural paradigms such as component-orientation, model-driven, and knowledge-based, standardised security services needed have to be specified and implemented in an integrated way following the same paradigm. This concerns the deployment of formal models, meta-languages, reference models such as the ISO RM-ODP, and development as well as implementation tools. International projects' results presented proceed on that streamline.
Aoki, Hirofumi; Ohno, Ryuzo; Yamaguchi, Takao
2005-01-01
In a virtual weightless environment, subjects' orientation skills were studied to examine what kind of cognitive errors people make when they moved through the interior space of virtual space stations and what kind of visual information effectively decreases those errors. Subjects wearing a head-mounted display moved from one end to the other end in space station-like routes constructed of rectangular and cubical modules, and did Pointing and Modeling tasks. In Experiment 1, configurations of the routes were changed with such variables as the number of bends, the number of embedding planes, and the number of planes with respect to the body posture. The results indicated that spatial orientation ability was relevant to the variables and that orientational errors were explained by two causes. One of these was that the place, the direction, and the sequence of turns were incorrect. The other was that subjects did not recognize the rotation of the frame of reference, especially when they turned in pitch direction rather than in yaw. In Experiment 2, the effect of the interior design was examined by testing three design settings. Wall colors that showed the allocentric frame of reference and the different interior design of vertical and horizontal modules were effective; however, there was a limit to the effectiveness in complicated configurations. c2005 Published by Elsevier Ltd.
Scientific communication in clinical psychology: examining patterns of citations and references.
Kiselica, Andrew M; Ruscio, John
2014-01-01
Previous studies of scientific communication used citation mapping, establishing psychology as a 'hub science' from which many other fields draw information. Within psychology, the clinical and counselling discipline is a major 'knowledge broker'. This study analyzed scientific communication among three major subdisciplines of clinical psychology-the cognitive-behavioural, psychodynamic and humanistic schools of thought-by examining patterns of references within and citations to 305 target articles published in leading journals of these subdisciplines. The results suggest that clinical researchers of each theoretical orientation engage in more insular scientific communication than an integrationist would find desirable and that cognitive-behavioural articles are more closely connected to mainstream psychology and related fields. Eclectic practitioners draw on several different theoretical orientations to inform their practice; as such, they should be interested in understanding the patterns of scientific communication within and across theoretical orientations. Practitioners work in a variety of different mental health settings, with a variety of other professionals in psychology-related fields, and should be interested in how much influence their particular theoretical orientation has on the work of colleagues. Many practitioners rely on new, evidence-based research to inform their work. The results of this study provide these individuals with an objective measure of the influence of empirical work in different areas of clinical psychology. Copyright © 2012 John Wiley & Sons, Ltd.
Jumpstarting Transit-Oriented Development Act
Sen. Bennet, Michael F. [D-CO
2012-02-01
Senate - 02/01/2012 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
Examining Long-Term Global Climate Change on the Web.
ERIC Educational Resources Information Center
Huntoon, Jacqueline E.; Ridky, Robert K.
2002-01-01
Describes a web-based, inquiry-oriented activity that enables students to examine long-term global climate change. Supports instruction in other topics such as population growth. (Contains 34 references.) (DDR)
Evidence for the value of health promotion interventions in natural disaster management.
Jackson, Suzanne F; Fazal, Nadia; Gravel, Geneviève; Papowitz, Heather
2017-12-01
A rapid review of literature was conducted to identify effective health promotion (HP) intervention strategies that relate to the management of disasters from natural hazards, including prevention, preparedness, response and recovery measures. Searches were conducted in formal literature from 2000 to 2011 and then updated to 2013. Out of 719 relevant abstracts, 57 studies were selected for more detailed review. In total, 16 studies were annotated for the narrative synthesis; these articles all reported an outcome-oriented evaluation of an HP-related intervention in a natural disaster situation in low- and middle-income countries (LMIC) or vulnerable populations in high-income countries (HIC). These 16 studies were also assessed for quality of their evaluation design. Although it was not possible to select only strong study designs, LMIC weak designs were matched with stronger designs in HIC most of the time. A narrative synthesis was conducted to report the results. In the preparedness and mitigation stages, there were six articles referring to four HP strategies. In the response and recovery phases, there were 10 articles referring to an additional four HP strategies. HP plays a role in regaining a sense of control after disaster through: engaging victims of disaster in group decisions (including children), collaboration and networking, recognition of local strengths and assets, conducting community needs assessments, respecting local knowledge, training local resources as part of an ongoing system and use of pre-existing community focal points or organizations as trusted locations for community services and reconnections. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Theory and Realization of Global Terrestrial Reference Systems
NASA Technical Reports Server (NTRS)
Ma, C.; Bolotin, S.; Gipson, J.; Gordon, D.; Le Bail, K.; MacMillan, D.
2010-01-01
Comparison of realizations of the terrestrial reference frame. IGN and DGFI both generated realizations of the terrestrial reference frame under the auspices of the IERS from combination of the same space geodetic data. We examined both results for VLBI sites using the full geodetic VLBI data set with respect to site positions and velocities and time series of station positions, baselines and Earth orientation parameters. One of the difficulties encountered was matching episodic breaks and periods of non-linear motion of the two realizations with the VLBI models. Our analysis and conclusions will be discussed.
New insights into action-perception coupling.
Feldman, Anatol G
2009-03-01
According to a view that has dominated the field for over a century, the brain programs muscle commands and uses a copy of these commands [efference copy (EC)] to adjust not only resulting motor action but also ongoing perception. This view was helpful in formulating several classical problems of action and perception: (1) the posture-movement problem of how movements away from a stable posture can be made without evoking resistance of posture-stabilizing mechanisms resulting from intrinsic muscle and reflex properties; (2) the problem of kinesthesia or why our sense of limb position is good despite ambiguous positional information delivered by proprioceptive and cutaneous signals; (3) the problem of visual space constancy or why the world is perceived as stable while its retinal image shifts following changes in gaze. On closer inspection, the EC theory actually does not solve these problems in a physiologically feasible way. Here solutions to these problems are proposed based on the advanced formulation of the equilibrium-point hypothesis that suggests that action and perception are accomplished in a common spatial frame of reference selected by the brain from a set of available frames. Experimental data suggest that the brain is also able to translate or/and rotate the selected frame of reference by modifying its major attributes-the origin, metrics and orientation-and thus substantially influence action and perception. Because of this ability, such frames are called physical to distinguish them from symbolic or mathematical frames that are used to describe system behavior without influencing this behavior. Experimental data also imply that once a frame of reference is chosen, its attributes are modified in a feedforward way, thus enabling the brain to act in an anticipatory and predictive manner. This approach is extended to sense of effort, kinesthetic illusions, phantom limb and phantom body phenomena. It also addresses the question of why retinal images of objects are sensed as objects located in the external, physical world, rather than in internal representations of the brain.
Allison, J D; Bonds, A B
1994-01-01
Intracortical inhibition is believed to enhance the orientation tuning of striate cortical neurons, but the origin of this inhibition is unclear. To examine the possible influence of ascending inhibitory projections from the infragranular layers of striate cortex on the orientation selectivity of neurons in the supragranular layers, we measured the spatiotemporal response properties of 32 supragranular neurons in the cat before, during, and after neural activity in the infragranular layers beneath the recorded cells was inactivated by iontophoretic administration of GABA. During GABA iontophoresis, the orientation tuning bandwidth of 15 (46.9%) supragranular neurons broadened as a result of increases in response amplitude to stimuli oriented about +/- 20 degrees away from the preferred stimulus angle. The mean (+/- SD) baseline orientation tuning bandwidth (half width at half height) of these neurons was 13.08 +/- 2.3 degrees. Their mean tuning bandwidth during inactivation of the infragranular layers increased to 19.59 +/- 2.54 degrees, an increase of 49.7%. The mean percentage increase in orientation tuning bandwidth of the individual neurons was 47.4%. Four neurons exhibited symmetrical changes in their orientation tuning functions, while 11 neurons displayed asymmetrical changes. The change in form of the orientation tuning functions appeared to depend on the relative vertical alignment of the recorded neuron and the infragranular region of inactivation. Neurons located in close vertical register with the inactivated infragranular tissue exhibited symmetric changes in their orientation tuning functions. The neurons exhibiting asymmetric changes in their orientation tuning functions were located just outside the vertical register. Eight of these 11 neurons also demonstrated a mean shift of 6.67 +/- 5.77 degrees in their preferred stimulus orientation. The magnitude of change in the orientation tuning functions increased as the delivery of GABA was prolonged. Responses returned to normal approximately 30 min after the delivery of GABA was discontinued. We conclude that inhibitory projections from neurons within the infragranular layers of striate cortex in cats can enhance the orientation selectivity of supragranular striate cortical neurons.
Three-dimensional anthropometry of the adult face.
DOT National Transportation Integrated Search
1978-03-01
This study describes a new three-dimensional anatomical axis system based on four conventional anthropometrical face landmarks. Coincident as a coordinate (orthogonal) axis system, this reference system was developed to provide convenient orientation...
ERIC Educational Resources Information Center
Altshuler, Ken
1994-01-01
Presents a method using art classics to teach that a third vector axis is required to represent orientations in three-dimensional space. Helps students understand the importance of perspective, frame of reference, balance, and color theory. (MVL)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kardash, Maria E.; Dzuba, Sergei A., E-mail: dzuba@kinetics.nsc.ru
Lipid-cholesterol interactions are responsible for different properties of biological membranes including those determining formation in the membrane of spatial inhomogeneities (lipid rafts). To get new information on these interactions, electron spin echo (ESE) spectroscopy, which is a pulsed version of electron paramagnetic resonance (EPR), was applied to study 3β-doxyl-5α-cholestane (DCh), a spin-labeled analog of cholesterol, in phospholipid bilayer consisted of equimolecular mixture of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine and 1,2-dioleoyl-sn-glycero-3-phosphocholine. DCh concentration in the bilayer was between 0.1 mol.% and 4 mol.%. For comparison, a reference system containing a spin-labeled 5-doxyl-stearic acid (5-DSA) instead of DCh was studied as well. The effects of “instantaneousmore » diffusion” in ESE decay and in echo-detected (ED) EPR spectra were explored for both systems. The reference system showed good agreement with the theoretical prediction for the model of spin labels of randomly distributed orientations, but the DCh system demonstrated remarkably smaller effects. The results were explained by assuming that neighboring DCh molecules are oriented in a correlative way. However, this correlation does not imply the formation of clusters of cholesterol molecules, because conventional continuous wave EPR spectra did not show the typical broadening due to aggregation of spin labels and the observed ESE decay was not faster than in the reference system. So the obtained data evidence that cholesterol molecules at low concentrations in biological membranes can interact via large distances of several nanometers which results in their orientational self-ordering.« less
Gravity in the Brain as a Reference for Space and Time Perception.
Lacquaniti, Francesco; Bosco, Gianfranco; Gravano, Silvio; Indovina, Iole; La Scaleia, Barbara; Maffei, Vincenzo; Zago, Myrka
2015-01-01
Moving and interacting with the environment require a reference for orientation and a scale for calibration in space and time. There is a wide variety of environmental clues and calibrated frames at different locales, but the reference of gravity is ubiquitous on Earth. The pull of gravity on static objects provides a plummet which, together with the horizontal plane, defines a three-dimensional Cartesian frame for visual images. On the other hand, the gravitational acceleration of falling objects can provide a time-stamp on events, because the motion duration of an object accelerated by gravity over a given path is fixed. Indeed, since ancient times, man has been using plumb bobs for spatial surveying, and water clocks or pendulum clocks for time keeping. Here we review behavioral evidence in favor of the hypothesis that the brain is endowed with mechanisms that exploit the presence of gravity to estimate the spatial orientation and the passage of time. Several visual and non-visual (vestibular, haptic, visceral) cues are merged to estimate the orientation of the visual vertical. However, the relative weight of each cue is not fixed, but depends on the specific task. Next, we show that an internal model of the effects of gravity is combined with multisensory signals to time the interception of falling objects, to time the passage through spatial landmarks during virtual navigation, to assess the duration of a gravitational motion, and to judge the naturalness of periodic motion under gravity.
Jacob, Francis; Guertler, Rea; Naim, Stephanie; Nixdorf, Sheri; Fedier, André; Hacker, Neville F.; Heinzelmann-Schwarz, Viola
2013-01-01
Reverse Transcription - quantitative Polymerase Chain Reaction (RT-qPCR) is a standard technique in most laboratories. The selection of reference genes is essential for data normalization and the selection of suitable reference genes remains critical. Our aim was to 1) review the literature since implementation of the MIQE guidelines in order to identify the degree of acceptance; 2) compare various algorithms in their expression stability; 3) identify a set of suitable and most reliable reference genes for a variety of human cancer cell lines. A PubMed database review was performed and publications since 2009 were selected. Twelve putative reference genes were profiled in normal and various cancer cell lines (n = 25) using 2-step RT-qPCR. Investigated reference genes were ranked according to their expression stability by five algorithms (geNorm, Normfinder, BestKeeper, comparative ΔCt, and RefFinder). Our review revealed 37 publications, with two thirds patient samples and one third cell lines. qPCR efficiency was given in 68.4% of all publications, but only 28.9% of all studies provided RNA/cDNA amount and standard curves. GeNorm and Normfinder algorithms were used in 60.5% in combination. In our selection of 25 cancer cell lines, we identified HSPCB, RRN18S, and RPS13 as the most stable expressed reference genes. In the subset of ovarian cancer cell lines, the reference genes were PPIA, RPS13 and SDHA, clearly demonstrating the necessity to select genes depending on the research focus. Moreover, a cohort of at least three suitable reference genes needs to be established in advance to the experiments, according to the guidelines. For establishing a set of reference genes for gene normalization we recommend the use of ideally three reference genes selected by at least three stability algorithms. The unfortunate lack of compliance to the MIQE guidelines reflects that these need to be further established in the research community. PMID:23554992
Peng, Xiong; Karakalos, Stavros G; Mustain, William E
2018-01-17
Selective electrochemical reduction of CO 2 is one of the most important processes to study because of its promise to convert this greenhouse gas to value-added chemicals at low cost. In this work, a simple anodization treatment was devised that first oxidizes Ag to Ag 2 CO 3 , then uses rapid electrochemical reduction to create preferentially oriented nanoparticles (PONs) of metallic Ag (PON-Ag) with high surface area as well as high activity and very high selectivity for the reduction of CO 2 to CO. The PON-Ag catalyst was dominated by (110) and (100) orientation, which allowed PON-Ag to achieve a CO Faradaic efficiency of 96.7% at an operating potential of -0.69 V vs RHE. This performance is not only significantly higher than that of polycrystalline Ag (60% at -0.87 V vs RHE) but also represents one of the best combinations of activity and selectivity achieved to date - all with a very simple, scalable approach to electrode fabrication.
Wave-plate structures, power selective optical filter devices, and optical systems using same
Koplow, Jeffrey P [San Ramon, CA
2012-07-03
In an embodiment, an optical filter device includes an input polarizer for selectively transmitting an input signal. The device includes a wave-plate structure positioned to receive the input signal, which includes first and second substantially zero-order, zero-wave plates arranged in series with and oriented at an angle relative to each other. The first and second zero-wave plates are configured to alter a polarization state of the input signal passing in a manner that depends on the power of the input signal. Each zero-wave plate includes an entry and exit wave plate each having a fast axis, with the fast axes oriented substantially perpendicular to each other. Each entry wave plate is oriented relative to a transmission axis of the input polarizer at a respective angle. An output polarizer is positioned to receive a signal output from the wave-plate structure and selectively transmits the signal based on the polarization state.
Sexual orientation in males and the evolution of anisogamy.
Reed, Lawrence Ian
2010-02-01
How might homosexual orientation have evolved and been maintained? Several adaptationist explanations have been examined in attempt to reconcile the presence of same-sex sexual behaviors with traditional selection-based theory, showing little empirical support. The current paper presents a novel adaptationist explanation for the evolution and maintenance of same-sex sexual behaviors in males, both between- and within-species, related to the evolution of anisogamy. Under conditions of isogamy, sexual reproduction occurs between individuals with gametes of similar morphology. With the evolution of anisogamy came greater specificity on the types of individuals that would produce offspring when mated with (i.e. those with opposing gamete sizes). It is suggested that with this evolutionary change, a specified psychological adaptation orienting individuals primarily towards mating partners with newly opposing gamete sizes was then selected for. It is thus hypothesized that sexual orientation will vary along the anisogamy-isogamy continuum, with homosexual orientation being associated with closer approximations towards isogamy. This hypothesis leads to two specific predictions. First, in comparisons between species, the presence of same-sex sexual behaviors will be more likely to occur as sperm to egg ratios approach 1:1. Second, in comparisons within species, those individuals with greater sperm lengths will be more likely to exhibit same-sex sexual behaviors than those with lesser sperm lengths. Examination of the present hypothesis stands to greatly increase our knowledge of the selective forces shaping both biological and psychological evolution.
Evaluating child care in the Family Health Strategy.
da Silva, Simone Albino; Fracolli, Lislaine Aparecida
2016-01-01
to evaluate the healthcare provided to children under two years old by the Family Health Strategy. evaluative, quantitative, cross-sectional study that used the Primary Care Assessment Tool - Child Version for measuring the access, longitudinality, coordination, integrality, family orientation and community orientation. a total of 586 adults responsible for children under two years old and linked to 33 health units in eleven municipalities of the state of Minas Gerais, Brazil, were interviewed. The evaluation was positive for the attributes longitudinality and coordination, and negative for access, integrality, Family orientation and community orientation. there are discrepancies between health needs of children and what is offered by the service; organizational barriers to access; absence of counter-reference; predominance of curative and long-standing and individual preventive practices; verticalization in organization of actions; and lack of good communication between professionals and users.
Improved ultrasonic standard reference blocks
NASA Technical Reports Server (NTRS)
Eitzen, D. G.; Sushinsky, G. F.; Chwirut, D. J.; Bechtoldt, C. J.; Ruff, A. W.
1976-01-01
A program to improve the quality, reproducibility and reliability of nondestructive testing through the development of improved ASTM-type ultrasonic reference standards is described. Reference blocks of aluminum, steel, and titanium alloys are to be considered. Equipment representing the state-of-the-art in laboratory and field ultrasonic equipment was obtained and evaluated. RF and spectral data on ten sets of ultrasonic reference blocks have been taken as part of a task to quantify the variability in response from nominally identical blocks. Techniques for residual stress, preferred orientation, and micro-structural measurements were refined and are applied to a reference block rejected by the manufacturer during fabrication in order to evaluate the effect of metallurgical condition on block response. New fabrication techniques for reference blocks are discussed and ASTM activities are summarized.
Zhang, Jie; Li, Yongxiang; Zheng, Jun; Zhang, Hongwei; Yang, Xiaohong; Wang, Jianhua; Wang, Guoying
2017-01-01
The extensive genetic variation present in maize (Zea mays) germplasm makes it possible to detect signatures of positive artificial selection that occurred during temperate and tropical maize improvement. Here we report an analysis of 532,815 polymorphisms from a maize association panel consisting of 368 diverse temperate and tropical inbred lines. We developed a gene-oriented approach adapting exonic polymorphisms to identify recently selected alleles by comparing haplotypes across the maize genome. This analysis revealed evidence of selection for more than 1100 genomic regions during recent improvement, and included regulatory genes and key genes with visible mutant phenotypes. We find that selected candidate target genes in temperate maize are enriched in biosynthetic processes, and further examination of these candidates highlights two cases, sucrose flux and oil storage, in which multiple genes in a common pathway can be cooperatively selected. Finally, based on available parallel gene expression data, we hypothesize that some genes were selected for regulatory variations, resulting in altered gene expression. PMID:28099470