Sample records for oscillation frequency correlation

  1. Coexistence of gamma and high-frequency oscillations in rat medial entorhinal cortex in vitro

    PubMed Central

    Cunningham, M O; Halliday, David M; Davies, Ceri H; Traub, Roger D; Buhl, Eberhard H; Whittington, Miles A

    2004-01-01

    High frequency oscillations (> 80–90 Hz) occur in neocortex and hippocampus in vivo where they are associated with specific behavioural states and more classical EEG frequency bands. In the hippocampus in vitro these oscillations can occur in the absence of pyramidal neuronal somatodendritic compartments and are temporally correlated with on-going, persistent gamma frequency oscillations. Their occurrence in the hippocampus is dependent on gap-junctional communication and it has been suggested that these high frequency oscillations originate as collective behaviour in populations of electrically coupled principal cell axonal compartments. Here we demonstrate that the superficial layers of medial entorhinal cortex can also generate high frequency oscillations associated with gamma rhythms. During persistent gamma frequency oscillations high frequency oscillations occur with a high bispectral coherence with the field gamma activity. Bursts of high frequency oscillations are temporally correlated with both the onset of compound excitatory postsynaptic potentials in fast-spiking interneurones and spikelet potentials in both pyramidal and stellate principal neurones. Both the gamma frequency and high frequency oscillations were attenuated by the gap junction blocker carbenoxolone. These data suggest that high frequency oscillations may represent the substrate for phasic drive to interneurones during persistent gamma oscillations in the medial entorhinal cortex. PMID:15254156

  2. Correlated states of a quantum oscillator acted by short pulses

    NASA Technical Reports Server (NTRS)

    Manko, O. V.

    1993-01-01

    Correlated squeezed states for a quantum oscillator are constructed based on the method of quantum integrals of motion. The quantum oscillator is acted upon by short duration pulses. Three delta-kickings of frequency are used to model the pulses' dependence upon the time aspects of the frequency of the oscillator. Additionally, the correlation coefficient and quantum variances of operations of coordinates and momenta are written in explicit form.

  3. Phase coherence induced by correlated disorder.

    PubMed

    Hong, Hyunsuk; O'Keeffe, Kevin P; Strogatz, Steven H

    2016-02-01

    We consider a mean-field model of coupled phase oscillators with quenched disorder in the coupling strengths and natural frequencies. When these two kinds of disorder are uncorrelated (and when the positive and negative couplings are equal in number and strength), it is known that phase coherence cannot occur and synchronization is absent. Here we explore the effects of correlating the disorder. Specifically, we assume that any given oscillator either attracts or repels all the others, and that the sign of the interaction is deterministically correlated with the given oscillator's natural frequency. For symmetrically correlated disorder with zero mean, we find that the system spontaneously synchronizes, once the width of the frequency distribution falls below a critical value. For asymmetrically correlated disorder, the model displays coherent traveling waves: the complex order parameter becomes nonzero and rotates with constant frequency different from the system's mean natural frequency. Thus, in both cases, correlated disorder can trigger phase coherence.

  4. Noise induced oscillations and coherence resonance in a generic model of the nonisothermal chemical oscillator

    PubMed Central

    Simakov, David S. A.; Pérez-Mercader, Juan

    2013-01-01

    Oscillating chemical reactions are common in biological systems and they also occur in artificial non-biological systems. Generally, these reactions are subject to random fluctuations in environmental conditions which translate into fluctuations in the values of physical variables, for example, temperature. We formulate a mathematical model for a nonisothermal minimal chemical oscillator containing a single negative feedback loop and study numerically the effects of stochastic fluctuations in temperature in the absence of any deterministic limit cycle or periodic forcing. We show that noise in temperature can induce sustained limit cycle oscillations with a relatively narrow frequency distribution and some characteristic frequency. These properties differ significantly depending on the noise correlation. Here, we have explored white and colored (correlated) noise. A plot of the characteristic frequency of the noise induced oscillations as a function of the correlation exponent shows a maximum, therefore indicating the existence of autonomous stochastic resonance, i.e. coherence resonance. PMID:23929212

  5. Low Frequency Quasi-periodic Oscillations in the High-eccentric LMXB Cir X-1: Extending the WK Correlation for Z Sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bu, Qingcui; Chen, Li; Belloni, T. M.

    Using archival Rossi X-ray Timing Explorer ( RXTE ) data, we studied the low-frequency quasi-periodic oscillations (LFQPOs) in the neutron star low-mass X-ray binary (LMXB) Cir X-1 and examined their contribution to frequency–frequency correlations for Z sources. We also studied the orbital phase effects on the LFQPO properties and found them to be phase independent. Comparing LFQPO frequencies in different classes of LMXBs, we found that systems that show both Z and atoll states form a common track with atoll/BH sources in the so-called WK correlation, while persistent Z systems are offset by a factor of about two. We foundmore » that neither source luminosity nor mass accretion rate is related to the shift of persistent Z systems. We discuss the possibility of a misidentification of fundamental frequency for horizontal branch oscillations from persistent Z systems and interpreted the oscillations in terms of models based on relativistic precession.« less

  6. Beta Peak Frequencies at Rest Correlate with Endogenous GABA+/Cr Concentrations in Sensorimotor Cortex Areas

    PubMed Central

    Baumgarten, Thomas J.; Oeltzschner, Georg; Hoogenboom, Nienke; Wittsack, Hans-Jörg; Schnitzler, Alfons; Lange, Joachim

    2016-01-01

    Neuronal oscillatory activity in the beta band (15–30 Hz) is a prominent signal within the human sensorimotor cortex. Computational modeling and pharmacological modulation studies suggest an influence of GABAergic interneurons on the generation of beta band oscillations. Accordingly, studies in humans have demonstrated a correlation between GABA concentrations and power of beta band oscillations. It remains unclear, however, if GABA concentrations also influence beta peak frequencies and whether this influence is present in the sensorimotor cortex at rest and without pharmacological modulation. In the present study, we investigated the relation between endogenous GABA concentration (measured by magnetic resonance spectroscopy) and beta oscillations (measured by magnetoencephalography) at rest in humans. GABA concentrations and beta band oscillations were measured for left and right sensorimotor and occipital cortex areas. A significant positive linear correlation between GABA concentration and beta peak frequency was found for the left sensorimotor cortex, whereas no significant correlations were found for the right sensorimotor and the occipital cortex. The results show a novel connection between endogenous GABA concentration and beta peak frequency at rest. This finding supports previous results that demonstrated a connection between oscillatory beta activity and pharmacologically modulated GABA concentration in the sensorimotor cortex. Furthermore, the results demonstrate that for a predominantly right-handed sample, the correlation between beta band oscillations and endogenous GABA concentrations is evident only in the left sensorimotor cortex. PMID:27258089

  7. Analytically exploiting noise correlations inside the feedback loop to improve locked-oscillator performance.

    PubMed

    Sastrawan, J; Jones, C; Akhalwaya, I; Uys, H; Biercuk, M J

    2016-08-01

    We introduce concepts from optimal estimation to the stabilization of precision frequency standards limited by noisy local oscillators. We develop a theoretical framework casting various measures for frequency standard variance in terms of frequency-domain transfer functions, capturing the effects of feedback stabilization via a time series of Ramsey measurements. Using this framework, we introduce an optimized hybrid predictive feedforward measurement protocol that employs results from multiple past measurements and transfer-function-based calculations of measurement covariance to improve the accuracy of corrections within the feedback loop. In the presence of common non-Markovian noise processes these measurements will be correlated in a calculable manner, providing a means to capture the stochastic evolution of the local oscillator frequency during the measurement cycle. We present analytic calculations and numerical simulations of oscillator performance under competing feedback schemes and demonstrate benefits in both correction accuracy and long-term oscillator stability using hybrid feedforward. Simulations verify that in the presence of uncompensated dead time and noise with significant spectral weight near the inverse cycle time predictive feedforward outperforms traditional feedback, providing a path towards developing a class of stabilization software routines for frequency standards limited by noisy local oscillators.

  8. Dominant side in single-leg stance stability during floor oscillations at various frequencies

    PubMed Central

    2014-01-01

    Background We investigated lateral dominance in the postural stability of single-leg stance with anteroposterior floor oscillations at various frequencies. Methods Thirty adults maintained a single-leg stance on a force platform for 20 seconds per trial. Trials were performed with no oscillation (static condition) and with anteroposterior floor oscillations (2.5-cm amplitude) at six frequencies: 0.25, 0.5, 0.75, 1.0, 1.25 and 1.5 Hz (dynamic condition). A set of three trials was performed on each leg in each oscillation frequency in random order. The mean speed of the center of pressure in the anteroposterior direction (CoPap) was calculated as an index of postural stability, and frequency analysis of CoPap sway was performed. Footedness for carrying out mobilizing activities was assessed with a questionnaire. Results CoPap speed exponentially increased as oscillation frequency increased in both legs. The frequency analysis of CoPap showed a peak <0.3 Hz at no oscillation. The frequency components at 0.25-Hz oscillation included common components with no oscillation and those at 1.5-Hz oscillation showed the maximum amplitude among all conditions. Postural stability showed no significant difference between left- and right-leg stance at no oscillation and oscillations ≤1.25 Hz, but at 1.5-Hz oscillation was significantly higher in the right-leg stance than in the left-leg stance. For the lateral dominance of postural stability at individual levels, the lateral difference in postural stability at no oscillation was positively correlated with that at 0.25-Hz oscillation (r = 0.51) and negatively correlated with that at 1.5-Hz oscillation (r = -0.53). For 70% of subjects, the dominant side of postural stability was different at no oscillation and 1.5-Hz oscillation. In the subjects with left- or right-side dominance at no oscillation, 94% or 38% changed their dominant side at 1.5-Hz oscillation, with a significant difference between these percentages. In the 1.5-Hz oscillation, 73% of subjects had concordance between the dominant side of postural stability and that of mobilizing footedness. Conclusion In static conditions, there was no lateral dominance of stability during single-leg stance. At 1.5-Hz oscillation, the highest frequency, right-side dominance of postural stability was recognized. Functional role in supporting leg may be divided between left and right legs according to the change of balance condition from static to dynamic. PMID:25127541

  9. Dynamic Interaction of Spindles and Gamma Activity during Cortical Slow Oscillations and Its Modulation by Subcortical Afferents

    PubMed Central

    Valencia, Miguel; Artieda, Julio; Bolam, J. Paul; Mena-Segovia, Juan

    2013-01-01

    Slow oscillations are a hallmark of slow wave sleep. They provide a temporal framework for a variety of phasic events to occur and interact during sleep, including the expression of high-frequency oscillations and the discharge of neurons across the entire brain. Evidence shows that the emergence of distinct high-frequency oscillations during slow oscillations facilitates the communication among brain regions whose activity was correlated during the preceding waking period. While the frequencies of oscillations involved in such interactions have been identified, their dynamics and the correlations between them require further investigation. Here we analyzed the structure and dynamics of these signals in anesthetized rats. We show that spindles and gamma oscillations coexist but have distinct temporal dynamics across the slow oscillation cycle. Furthermore, we observed that spindles and gamma are functionally coupled to the slow oscillations and between each other. Following the activation of ascending pathways from the brainstem by means of a carbachol injection in the pedunculopontine nucleus, we were able to modify the gain in the gamma oscillations that are independent of the spindles while the spindle amplitude was reduced. Furthermore, carbachol produced a decoupling of the gamma oscillations that are dependent on the spindles but with no effect on their amplitude. None of the changes in the high-frequency oscillations affected the onset or shape of the slow oscillations, suggesting that slow oscillations occur independently of the phasic events that coexist with them. Our results provide novel insights into the regulation, dynamics and homeostasis of cortical slow oscillations. PMID:23844020

  10. Finding brain oscillations with power dependencies in neuroimaging data.

    PubMed

    Dähne, Sven; Nikulin, Vadim V; Ramírez, David; Schreier, Peter J; Müller, Klaus-Robert; Haufe, Stefan

    2014-08-01

    Phase synchronization among neuronal oscillations within the same frequency band has been hypothesized to be a major mechanism for communication between different brain areas. On the other hand, cross-frequency communications are more flexible allowing interactions between oscillations with different frequencies. Among such cross-frequency interactions amplitude-to-amplitude interactions are of a special interest as they show how the strength of spatial synchronization in different neuronal populations relates to each other during a given task. While, previously, amplitude-to-amplitude correlations were studied primarily on the sensor level, we present a source separation approach using spatial filters which maximize the correlation between the envelopes of brain oscillations recorded with electro-/magnetoencephalography (EEG/MEG) or intracranial multichannel recordings. Our approach, which is called canonical source power correlation analysis (cSPoC), is thereby capable of extracting genuine brain oscillations solely based on their assumed coupling behavior even when the signal-to-noise ratio of the signals is low. In addition to using cSPoC for the analysis of cross-frequency interactions in the same subject, we show that it can also be utilized for studying amplitude dynamics of neuronal oscillations across subjects. We assess the performance of cSPoC in simulations as well as in three distinctively different analysis scenarios of real EEG data, each involving several subjects. In the simulations, cSPoC outperforms unsupervised state-of-the-art approaches. In the analysis of real EEG recordings, we demonstrate excellent unsupervised discovery of meaningful power-to-power couplings, within as well as across subjects and frequency bands. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Detecting scaling in the period dynamics of multimodal signals: Application to Parkinsonian tremor

    NASA Astrophysics Data System (ADS)

    Sapir, Nir; Karasik, Roman; Havlin, Shlomo; Simon, Ely; Hausdorff, Jeffrey M.

    2003-03-01

    Patients with Parkinson’s disease exhibit tremor, involuntary movement of the limbs. The frequency spectrum of tremor typically has broad peaks at “harmonic” frequencies, much like that seen in other physical processes. In general, this type of harmonic structure in the frequency domain may be due to two possible mechanisms: a nonlinear oscillation or a superposition of (multiple) independent modes of oscillation. A broad peak spectrum generally indicates that a signal is semiperiodic with a fluctuating period. These fluctuations may posses intrinsic order that can be quantified using scaling analysis. We propose a method to extract the correlation (scaling) properties in the period dynamics of multimodal oscillations, in order to distinguish between a nonlinear oscillation and a superposition of individual modes of oscillation. The method is based on our finding that the information content of the temporal correlations in a fluctuating period of a single oscillator is contained in a finite frequency band in the power spectrum, allowing for decomposition of modes by bandpass filtering. Our simulations for a nonlinear oscillation show that harmonic modes possess the same scaling properties. In contrast, when the method is applied to tremor records from patients with Parkinson’s disease, the first two modes of oscillations yield different scaling patterns, suggesting that these modes may not be simple harmonics, as might be initially assumed.

  12. Ictal high frequency oscillations distinguish two types of seizure territories in humans

    PubMed Central

    Weiss, Shennan A.; Banks, Garrett P.; McKhann, Guy M.; Goodman, Robert R.; Emerson, Ronald G.; Trevelyan, Andrew J.

    2013-01-01

    High frequency oscillations have been proposed as a clinically useful biomarker of seizure generating sites. We used a unique set of human microelectrode array recordings (four patients, 10 seizures), in which propagating seizure wavefronts could be readily identified, to investigate the basis of ictal high frequency activity at the cortical (subdural) surface. Sustained, repetitive transient increases in high gamma (80–150 Hz) amplitude, phase-locked to the low-frequency (1–25 Hz) ictal rhythm, correlated with strong multi-unit firing bursts synchronized across the core territory of the seizure. These repetitive high frequency oscillations were seen in recordings from subdural electrodes adjacent to the microelectrode array several seconds after seizure onset, following ictal wavefront passage. Conversely, microelectrode recordings demonstrating only low-level, heterogeneous neural firing correlated with a lack of high frequency oscillations in adjacent subdural recording sites, despite the presence of a strong low-frequency signature. Previously, we reported that this pattern indicates a failure of the seizure to invade the area, because of a feedforward inhibitory veto mechanism. Because multi-unit firing rate and high gamma amplitude are closely related, high frequency oscillations can be used as a surrogate marker to distinguish the core seizure territory from the surrounding penumbra. We developed an efficient measure to detect delayed-onset, sustained ictal high frequency oscillations based on cross-frequency coupling between high gamma amplitude and the low-frequency (1–25 Hz) ictal rhythm. When applied to the broader subdural recording, this measure consistently predicted the timing or failure of ictal invasion, and revealed a surprisingly small and slowly spreading seizure core surrounded by a far larger penumbral territory. Our findings thus establish an underlying neural mechanism for delayed-onset, sustained ictal high frequency oscillations, and provide a practical, efficient method for using them to identify the small ictal core regions. Our observations suggest that it may be possible to reduce substantially the extent of cortical resections in epilepsy surgery procedures without compromising seizure control. PMID:24176977

  13. A one-parametric formula relating the frequencies of twin-peak quasi-periodic oscillations

    NASA Astrophysics Data System (ADS)

    Török, Gabriel; Goluchová, Kateřina; Šrámková, Eva; Horák, Jiří; Bakala, Pavel; Urbanec, Martin

    2017-12-01

    Timing analysis of X-ray flux in more than a dozen low-mass X-ray binary systems containing a neutron star reveals remarkable correlations between frequencies of two characteristic peaks present in the power-density spectra. We find a simple analytic relation that well reproduces all these individual correlations. We link this relation to a physical model which involves accretion rate modulation caused by an oscillating torus.

  14. Why earthquakes correlate weakly with the solid Earth tides: Effects of periodic stress on the rate and probability of earthquake occurrence

    USGS Publications Warehouse

    Beeler, N.M.; Lockner, D.A.

    2003-01-01

    We provide an explanation why earthquake occurrence does not correlate well with the daily solid Earth tides. The explanation is derived from analysis of laboratory experiments in which faults are loaded to quasiperiodic failure by the combined action of a constant stressing rate, intended to simulate tectonic loading, and a small sinusoidal stress, analogous to the Earth tides. Event populations whose failure times correlate with the oscillating stress show two modes of response; the response mode depends on the stressing frequency. Correlation that is consistent with stress threshold failure models, e.g., Coulomb failure, results when the period of stress oscillation exceeds a characteristic time tn; the degree of correlation between failure time and the phase of the driving stress depends on the amplitude and frequency of the stress oscillation and on the stressing rate. When the period of the oscillating stress is less than tn, the correlation is not consistent with threshold failure models, and much higher stress amplitudes are required to induce detectable correlation with the oscillating stress. The physical interpretation of tn is the duration of failure nucleation. Behavior at the higher frequencies is consistent with a second-order dependence of the fault strength on sliding rate which determines the duration of nucleation and damps the response to stress change at frequencies greater than 1/tn. Simple extrapolation of these results to the Earth suggests a very weak correlation of earthquakes with the daily Earth tides, one that would require >13,000 earthquakes to detect. On the basis of our experiments and analysis, the absence of definitive daily triggering of earthquakes by the Earth tides requires that for earthquakes, tn exceeds the daily tidal period. The experiments suggest that the minimum typical duration of earthquake nucleation on the San Andreas fault system is ???1 year.

  15. Oscillations in motor unit discharge are reflected in the low-frequency component of rectified surface EMG and the rate of change in force.

    PubMed

    Yoshitake, Yasuhide; Shinohara, Minoru

    2013-11-01

    Common drive to a motor unit (MU) pool manifests as low-frequency oscillations in MU discharge rate, producing fluctuations in muscle force. The aim of the study was to examine the temporal correlation between instantaneous MU discharge rate and rectified EMG in low frequencies. Additionally, we attempted to examine whether there is a temporal correlation between the low-frequency oscillations in MU discharge rate and the first derivative of force (dF/dt). Healthy young subjects produced steady submaximal force with their right finger as a single task or while maintaining a pinch-grip force with the left hand as a dual task. Surface EMG and fine-wire MU potentials were recorded from the first dorsal interosseous muscle in the right hand. Surface EMG was band-pass filtered (5-1,000 Hz) and full-wave rectified. Rectified surface EMG and the instantaneous discharge rate of MUs were smoothed by a Hann-window of 400 ms duration (equivalent to 2 Hz low-pass filtering). In each of the identified MUs, the smoothed MU discharge rate was positively correlated with the rectified-and-smoothed EMG as confirmed by the distinct peak in cross-correlation function with greater values in the dual task compared with the single task. Additionally, the smoothed MU discharge rate was temporally correlated with dF/dt more than with force and with rectified-and-smoothed EMG. The results indicated that the low-frequency component of rectified surface EMG and the first derivative of force provide temporal information on the low-frequency oscillations in the MU discharge rate.

  16. Dynamics of the solar chromosphere. I - Long-period network oscillations

    NASA Technical Reports Server (NTRS)

    Lites, B. W.; Rutten, R. J.; Kalkofen, W.

    1993-01-01

    We analyze differences in solar oscillations between the chromospheric network and internetwork regions from a 1 hr sequence of spectrograms of a quiet region near disk center. The spectrograms contain Ca II H, Ca I 422.7 nm, and various Fe I blends in the Ca II H wing. They permit vertical tracing of oscillations throughout the photosphere and into the low chromosphere. We find that the rms amplitude of Ca II H line center Doppler fluctuations is about 1.5 km/s for both network and internetwork, but that the character of the oscillations differs markedly in these two regions. Within internetwork areas the chromospheric velocity power spectrum is dominated by oscillations with frequencies at and above the acoustic cutoff frequency. They are well correlated with the oscillations in the underlying photosphere, but they are much reduced in the network. In contrast, the network Ca II H line center velocity and intensity power spectra are dominated by low-frequency oscillations with periods of 5-20 min. Their signature is much clearer in our Ca II H line center measurements than in previously used diagnostics which are contaminated by signals from deeper layers. We find that these long-period oscillations are not correlated with underlying photospheric disturbances, and we discuss their nature.

  17. Multifaceted roles for low-frequency oscillations in bottom-up and top-down processing during navigation and memory.

    PubMed

    Ekstrom, Arne D; Watrous, Andrew J

    2014-01-15

    A prominent and replicated finding is the correlation between running speed and increases in low-frequency oscillatory activity in the hippocampal local field potential. A more recent finding concerns low-frequency oscillations that increase in coherence between the hippocampus and neocortical brain areas such as prefrontal cortex during memory-related behaviors (i.e., remembering the correct location to visit). In this review, we tie together movement-related and memory-related low-frequency oscillations in the rodent with similar findings in humans. We argue that although movement-related low-frequency oscillations, in particular, may have slightly different characteristics in humans than rodents, placing important constraints on our thinking about this issue, both phenomena have similar functional foundations. We review four prominent theoretical models that provide partially conflicting accounts of movement-related low-frequency oscillations. We attempt to tie together these theoretical proposals, and existing data in rodents and humans, with memory-related low-frequency oscillations. We propose that movement-related low-frequency oscillations and memory-related low-frequency oscillatory activity, both of which show significant coherence with oscillations in other brain regions, represent different facets of "spectral fingerprints," or different resonant frequencies within the same brain networks underlying different cognitive processes. Together, movement-related and memory-related low-frequency oscillatory coupling may be linked by their distinct contributions to bottom-up, sensorimotor driven processing and top-down, controlled processing characterizing aspects of memory encoding and retrieval. Copyright © 2013. Published by Elsevier Inc.

  18. Multifaceted roles for low-frequency oscillations in bottom-up and top-down processing during navigation and memory

    PubMed Central

    Ekstrom, Arne D.; Watrous, Andrew J.

    2014-01-01

    A prominent and replicated finding is the correlation between running speed and increases in low-frequency oscillatory activity in the hippocampal local field potential. A more recent finding concerns low-frequency oscillations that increase in coherence between the hippocampus and neocortical brain areas such as prefrontal cortex during memory-related behaviors (i.e., remembering the correct arm to explore). In this review, we tie together movement-related and memory-related low-frequency oscillations in the rodent with similar findings in humans. We argue that although movement-related low-frequency oscillations, in particular, may have slightly different characteristics in humans than rodents, placing important constraints on our thinking about this issue, both phenomena have similar functional foundations. We review four prominent theoretical models that provide partially conflicting accounts of movement-related low-frequency oscillations. We attempt to tie together these theoretical proposals, and existing data in rodents and humans, with memory-related low-frequency oscillations. We propose that movement-related low-frequency oscillations and memory-related low-frequency oscillatory activity, both of which show significant coherence with oscillations in other brain regions, represent different facets of “spectral fingerprints,” or different resonant frequencies within the same brain networks underlying different cognitive processes. Together, movement-related and memory-related low-frequency oscillatory coupling may be linked by their distinct contributions to bottom-up, sensorimotor driven processing and top-down, controlled processing characterizing aspects of memory encoding and retrieval. PMID:23792985

  19. Nondegenerate parametric oscillations in a tunable superconducting resonator

    NASA Astrophysics Data System (ADS)

    Bengtsson, Andreas; Krantz, Philip; Simoen, Michaël; Svensson, Ida-Maria; Schneider, Ben; Shumeiko, Vitaly; Delsing, Per; Bylander, Jonas

    2018-04-01

    We investigate nondegenerate parametric oscillations in a superconducting microwave multimode resonator that is terminated by a superconducting quantum interference device (SQUID). The parametric effect is achieved by modulating magnetic flux through the SQUID at a frequency close to the sum of two resonator-mode frequencies. For modulation amplitudes exceeding an instability threshold, self-sustained oscillations are observed in both modes. The amplitudes of these oscillations show good quantitative agreement with a theoretical model. The oscillation phases are found to be correlated and exhibit strong fluctuations which broaden the oscillation spectral linewidths. These linewidths are significantly reduced by applying a weak on-resonant tone, which also suppresses the phase fluctuations. When the weak tone is detuned, we observe synchronization of the oscillation frequency with the frequency of the input. For the detuned input, we also observe an emergence of three idlers in the output. This observation is in agreement with theory indicating four-mode amplification and squeezing of a coherent input.

  20. Cholinergic enhancement of visual attention and neural oscillations in the human brain.

    PubMed

    Bauer, Markus; Kluge, Christian; Bach, Dominik; Bradbury, David; Heinze, Hans Jochen; Dolan, Raymond J; Driver, Jon

    2012-03-06

    Cognitive processes such as visual perception and selective attention induce specific patterns of brain oscillations. The neurochemical bases of these spectral changes in neural activity are largely unknown, but neuromodulators are thought to regulate processing. The cholinergic system is linked to attentional function in vivo, whereas separate in vitro studies show that cholinergic agonists induce high-frequency oscillations in slice preparations. This has led to theoretical proposals that cholinergic enhancement of visual attention might operate via gamma oscillations in visual cortex, although low-frequency alpha/beta modulation may also play a key role. Here we used MEG to record cortical oscillations in the context of administration of a cholinergic agonist (physostigmine) during a spatial visual attention task in humans. This cholinergic agonist enhanced spatial attention effects on low-frequency alpha/beta oscillations in visual cortex, an effect correlating with a drug-induced speeding of performance. By contrast, the cholinergic agonist did not alter high-frequency gamma oscillations in visual cortex. Thus, our findings show that cholinergic neuromodulation enhances attentional selection via an impact on oscillatory synchrony in visual cortex, for low rather than high frequencies. We discuss this dissociation between high- and low-frequency oscillations in relation to proposals that lower-frequency oscillations are generated by feedback pathways within visual cortex. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. [The noncoherent components of evoked brain activity].

    PubMed

    Kovalev, V P; Novototskiĭ-Vlasov, V Iu

    1998-01-01

    Poststimulus spectral EEG changes and their correlation with evoked potential (EP) were analyzed. The non-stationary components of the brain evoked activity were revealed in 32 volunteers during simple motor reaction and choice reaction to visual stimuli. This nonstationary activity was manifested in poststimulus changes in the mean wave half-period duration (MWHPD) and mean wave half-period power of the delta- and beta-frequency oscillations computed in the EEG realizations after the EP subtraction. The latencies of high-frequency EP components fell into the intervals of the MWHPD decrease and increase in the power of beta-oscillations, and the latencies of low-frequency EP components coincided with the intervals of the MWHPD increase and decrease in the power of delta and beta-oscillations, which pointed to correlation of these changes with the EP.

  2. Detecting the BCS pairing amplitude via a sudden lattice ramp in a honeycomb lattice

    NASA Astrophysics Data System (ADS)

    Tiesinga, Eite; Nuske, Marlon; Mathey, Ludwig

    2016-05-01

    We determine the exact time evolution of an initial Bardeen-Cooper-Schrieffer (BCS) state of ultra-cold atoms in a hexagonal optical lattice. The dynamical evolution is triggered by ramping the lattice potential up, such that the interaction strength Uf is much larger than the hopping amplitude Jf. The quench initiates collective oscillations with frequency | Uf | /(2 π) in the momentum occupation numbers and imprints an oscillating phase with the same frequency on the order parameter Δ. The latter is not reproduced by treating the time evolution in mean-field theory. The momentum density-density or noise correlation functions oscillate at frequency | Uf | /(2 π) as well as its second harmonic. For a very deep lattice, with negligible tunneling energy, the oscillations of momentum occupation numbers are undamped. Non-zero tunneling after the quench leads to dephasing of the different momentum modes and a subsequent damping of the oscillations. This occurs even for a finite-temperature initial BCS state, but not for a non-interacting Fermi gas. We therefore propose to use this dephasing to detect a BCS state. Finally, we predict that the noise correlation functions in a honeycomb lattice will develop strong anti-correlations near the Dirac point. We acknowledge funding from the National Science Foundation.

  3. The θ-γ neural code.

    PubMed

    Lisman, John E; Jensen, Ole

    2013-03-20

    Theta and gamma frequency oscillations occur in the same brain regions and interact with each other, a process called cross-frequency coupling. Here, we review evidence for the following hypothesis: that the dual oscillations form a code for representing multiple items in an ordered way. This form of coding has been most clearly demonstrated in the hippocampus, where different spatial information is represented in different gamma subcycles of a theta cycle. Other experiments have tested the functional importance of oscillations and their coupling. These involve correlation of oscillatory properties with memory states, correlation with memory performance, and effects of disrupting oscillations on memory. Recent work suggests that this coding scheme coordinates communication between brain regions and is involved in sensory as well as memory processes. Copyright © 2013 Elsevier Inc. All rights reserved.

  4. CHARACTERIZING INTERMITTENCY OF 4-Hz QUASI-PERIODIC OSCILLATION IN XTE J1550–564 USING HILBERT–HUANG TRANSFORM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Su, Yi-Hao; Chou, Yi; Hu, Chin-Ping

    We present time-frequency analysis results based on the Hilbert–Huang transform (HHT) for the evolution of a 4-Hz low-frequency quasi-periodic oscillation (LFQPO) around the black hole X-ray binary XTE J1550–564. The origin of LFQPOs is still debated. To understand the cause of the peak broadening, we utilized a recently developed time-frequency analysis, HHT, for tracking the evolution of the 4-Hz LFQPO from XTE J1550–564. By adaptively decomposing the ∼4-Hz oscillatory component from the light curve and acquiring its instantaneous frequency, the Hilbert spectrum illustrates that the LFQPO is composed of a series of intermittent oscillations appearing occasionally between 3 and 5more » Hz. We further characterized this intermittency by computing the confidence limits of the instantaneous amplitudes of the intermittent oscillations, and constructed both the distributions of the QPO’s high- and low-amplitude durations, which are the time intervals with and without significant ∼4-Hz oscillations, respectively. The mean high-amplitude duration is 1.45 s and 90% of the oscillation segments have lifetimes below 3.1 s. The mean low-amplitude duration is 0.42 s and 90% of these segments are shorter than 0.73 s. In addition, these intermittent oscillations exhibit a correlation between the oscillation’s rms amplitude and mean count rate. This correlation could be analogous to the linear rms-flux relation found in the 4-Hz LFQPO through Fourier analysis. We conclude that the LFQPO peak in the power spectrum is broadened owing to intermittent oscillations with varying frequencies, which could be explained by using the Lense–Thirring precession model.« less

  5. Collisionless damping of flows in the TJ-II stellarator

    NASA Astrophysics Data System (ADS)

    Sánchez, E.; Kleiber, R.; Hatzky, R.; Borchardt, M.; Monreal, P.; Castejón, F.; López-Fraguas, A.; Sáez, X.; Velasco, J. L.; Calvo, I.; Alonso, A.; López-Bruna, D.

    2013-01-01

    The results of global linear gyrokinetic simulations of residual flows carried out with the code EUTERPE in the TJ-II three-dimensional geometry are reported. The linear response of the plasma to potential perturbations homogeneous in a magnetic surface shows several oscillation frequencies: a Geodesic-acoustic-mode-like frequency, in qualitative agreement with the formula given by Sugama and Watanabe (2006 Plasma Phys. 72 825), and a much lower frequency oscillation in agreement with the predictions of Mishchenko et al (2008 Phys. Plasmas 15 072309) and Helander et al (2011 Plasma Phys. Control. Fusion 53 054006) for stellarators. The dependence of both oscillations on ion and electron temperatures and the magnetic configuration is studied. The low-frequency oscillations are in the frequency range supporting the long-range correlations between potential signals experimentally observed in TJ-II.

  6. Coupled opto-electronic oscillator

    NASA Technical Reports Server (NTRS)

    Yao, X. Steve (Inventor); Maleki, Lute (Inventor)

    1999-01-01

    A coupled opto-electronic oscillator that directly couples a laser oscillation with an electronic oscillation to simultaneously achieve a stable RF oscillation at a high frequency and ultra-short optical pulsation by mode locking with a high repetition rate and stability. Single-mode selection can be achieved even with a very long opto-electronic loop. A multimode laser can be used to pump the electronic oscillation, resulting in a high operation efficiency. The optical and the RF oscillations are correlated to each other.

  7. Metastability and Inter-Band Frequency Modulation in Networks of Oscillating Spiking Neuron Populations

    PubMed Central

    Bhowmik, David; Shanahan, Murray

    2013-01-01

    Groups of neurons firing synchronously are hypothesized to underlie many cognitive functions such as attention, associative learning, memory, and sensory selection. Recent theories suggest that transient periods of synchronization and desynchronization provide a mechanism for dynamically integrating and forming coalitions of functionally related neural areas, and that at these times conditions are optimal for information transfer. Oscillating neural populations display a great amount of spectral complexity, with several rhythms temporally coexisting in different structures and interacting with each other. This paper explores inter-band frequency modulation between neural oscillators using models of quadratic integrate-and-fire neurons and Hodgkin-Huxley neurons. We vary the structural connectivity in a network of neural oscillators, assess the spectral complexity, and correlate the inter-band frequency modulation. We contrast this correlation against measures of metastable coalition entropy and synchrony. Our results show that oscillations in different neural populations modulate each other so as to change frequency, and that the interaction of these fluctuating frequencies in the network as a whole is able to drive different neural populations towards episodes of synchrony. Further to this, we locate an area in the connectivity space in which the system directs itself in this way so as to explore a large repertoire of synchronous coalitions. We suggest that such dynamics facilitate versatile exploration, integration, and communication between functionally related neural areas, and thereby supports sophisticated cognitive processing in the brain. PMID:23614040

  8. Data mining neocortical high-frequency oscillations in epilepsy and controls

    PubMed Central

    Stead, Matt; Krieger, Abba; Stacey, William; Maus, Douglas; Marsh, Eric; Viventi, Jonathan; Lee, Kendall H.; Marsh, Richard; Litt, Brian; Worrell, Gregory A.

    2011-01-01

    Transient high-frequency (100–500 Hz) oscillations of the local field potential have been studied extensively in human mesial temporal lobe. Previous studies report that both ripple (100–250 Hz) and fast ripple (250–500 Hz) oscillations are increased in the seizure-onset zone of patients with mesial temporal lobe epilepsy. Comparatively little is known, however, about their spatial distribution with respect to seizure-onset zone in neocortical epilepsy, or their prevalence in normal brain. We present a quantitative analysis of high-frequency oscillations and their rates of occurrence in a group of nine patients with neocortical epilepsy and two control patients with no history of seizures. Oscillations were automatically detected and classified using an unsupervised approach in a data set of unprecedented volume in epilepsy research, over 12 terabytes of continuous long-term micro- and macro-electrode intracranial recordings, without human preprocessing, enabling selection-bias-free estimates of oscillation rates. There are three main results: (i) a cluster of ripple frequency oscillations with median spectral centroid = 137 Hz is increased in the seizure-onset zone more frequently than a cluster of fast ripple frequency oscillations (median spectral centroid = 305 Hz); (ii) we found no difference in the rates of high frequency oscillations in control neocortex and the non-seizure-onset zone neocortex of patients with epilepsy, despite the possibility of different underlying mechanisms of generation; and (iii) while previous studies have demonstrated that oscillations recorded by parenchyma-penetrating micro-electrodes have higher peak 100–500 Hz frequencies than penetrating macro-electrodes, this was not found for the epipial electrodes used here to record from the neocortical surface. We conclude that the relative rate of ripple frequency oscillations is a potential biomarker for epileptic neocortex, but that larger prospective studies correlating high-frequency oscillations rates with seizure-onset zone, resected tissue and surgical outcome are required to determine the true predictive value. PMID:21903727

  9. Data mining neocortical high-frequency oscillations in epilepsy and controls.

    PubMed

    Blanco, Justin A; Stead, Matt; Krieger, Abba; Stacey, William; Maus, Douglas; Marsh, Eric; Viventi, Jonathan; Lee, Kendall H; Marsh, Richard; Litt, Brian; Worrell, Gregory A

    2011-10-01

    Transient high-frequency (100-500 Hz) oscillations of the local field potential have been studied extensively in human mesial temporal lobe. Previous studies report that both ripple (100-250 Hz) and fast ripple (250-500 Hz) oscillations are increased in the seizure-onset zone of patients with mesial temporal lobe epilepsy. Comparatively little is known, however, about their spatial distribution with respect to seizure-onset zone in neocortical epilepsy, or their prevalence in normal brain. We present a quantitative analysis of high-frequency oscillations and their rates of occurrence in a group of nine patients with neocortical epilepsy and two control patients with no history of seizures. Oscillations were automatically detected and classified using an unsupervised approach in a data set of unprecedented volume in epilepsy research, over 12 terabytes of continuous long-term micro- and macro-electrode intracranial recordings, without human preprocessing, enabling selection-bias-free estimates of oscillation rates. There are three main results: (i) a cluster of ripple frequency oscillations with median spectral centroid = 137 Hz is increased in the seizure-onset zone more frequently than a cluster of fast ripple frequency oscillations (median spectral centroid = 305 Hz); (ii) we found no difference in the rates of high frequency oscillations in control neocortex and the non-seizure-onset zone neocortex of patients with epilepsy, despite the possibility of different underlying mechanisms of generation; and (iii) while previous studies have demonstrated that oscillations recorded by parenchyma-penetrating micro-electrodes have higher peak 100-500 Hz frequencies than penetrating macro-electrodes, this was not found for the epipial electrodes used here to record from the neocortical surface. We conclude that the relative rate of ripple frequency oscillations is a potential biomarker for epileptic neocortex, but that larger prospective studies correlating high-frequency oscillations rates with seizure-onset zone, resected tissue and surgical outcome are required to determine the true predictive value.

  10. Oscillation Baselining and Analysis Tool

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    PNNL developed a new tool for oscillation analysis and baselining. This tool has been developed under a new DOE Grid Modernization Laboratory Consortium (GMLC) Project (GM0072 - “Suite of open-source applications and models for advanced synchrophasor analysis”) and it is based on the open platform for PMU analysis. The Oscillation Baselining and Analysis Tool (OBAT) performs the oscillation analysis and identifies modes of oscillations (frequency, damping, energy, and shape). The tool also does oscillation event baselining (fining correlation between oscillations characteristics and system operating conditions).

  11. Stereotyped high-frequency oscillations discriminate seizure onset zones and critical functional cortex in focal epilepsy.

    PubMed

    Liu, Su; Gurses, Candan; Sha, Zhiyi; Quach, Michael M; Sencer, Altay; Bebek, Nerses; Curry, Daniel J; Prabhu, Sujit; Tummala, Sudhakar; Henry, Thomas R; Ince, Nuri F

    2018-01-30

    High-frequency oscillations in local field potentials recorded with intracranial EEG are putative biomarkers of seizure onset zones in epileptic brain. However, localized 80-500 Hz oscillations can also be recorded from normal and non-epileptic cerebral structures. When defined only by rate or frequency, physiological high-frequency oscillations are indistinguishable from pathological ones, which limit their application in epilepsy presurgical planning. We hypothesized that pathological high-frequency oscillations occur in a repetitive fashion with a similar waveform morphology that specifically indicates seizure onset zones. We investigated the waveform patterns of automatically detected high-frequency oscillations in 13 epilepsy patients and five control subjects, with an average of 73 subdural and intracerebral electrodes recorded per patient. The repetitive oscillatory waveforms were identified by using a pipeline of unsupervised machine learning techniques and were then correlated with independently clinician-defined seizure onset zones. Consistently in all patients, the stereotypical high-frequency oscillations with the highest degree of waveform similarity were localized within the seizure onset zones only, whereas the channels generating high-frequency oscillations embedded in random waveforms were found in the functional regions independent from the epileptogenic locations. The repetitive waveform pattern was more evident in fast ripples compared to ripples, suggesting a potential association between waveform repetition and the underlying pathological network. Our findings provided a new tool for the interpretation of pathological high-frequency oscillations that can be efficiently applied to distinguish seizure onset zones from functionally important sites, which is a critical step towards the translation of these signature events into valid clinical biomarkers.awx374media15721572971001. © The Author(s) (2018). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. High-frequency neural oscillations and visual processing deficits in schizophrenia

    PubMed Central

    Tan, Heng-Ru May; Lana, Luiz; Uhlhaas, Peter J.

    2013-01-01

    Visual information is fundamental to how we understand our environment, make predictions, and interact with others. Recent research has underscored the importance of visuo-perceptual dysfunctions for cognitive deficits and pathophysiological processes in schizophrenia. In the current paper, we review evidence for the relevance of high frequency (beta/gamma) oscillations towards visuo-perceptual dysfunctions in schizophrenia. In the first part of the paper, we examine the relationship between beta/gamma band oscillations and visual processing during normal brain functioning. We then summarize EEG/MEG-studies which demonstrate reduced amplitude and synchrony of high-frequency activity during visual stimulation in schizophrenia. In the final part of the paper, we identify neurobiological correlates as well as offer perspectives for future research to stimulate further inquiry into the role of high-frequency oscillations in visual processing impairments in the disorder. PMID:24130535

  13. Explosive synchronization transitions in complex neural networks.

    PubMed

    Chen, Hanshuang; He, Gang; Huang, Feng; Shen, Chuansheng; Hou, Zhonghuai

    2013-09-01

    It has been recently reported that explosive synchronization transitions can take place in networks of phase oscillators [Gómez-Gardeñes et al. Phys. Rev. Lett. 106, 128701 (2011)] and chaotic oscillators [Leyva et al. Phys. Rev. Lett. 108, 168702 (2012)]. Here, we investigate the effect of a microscopic correlation between the dynamics and the interacting topology of coupled FitzHugh-Nagumo oscillators on phase synchronization transition in Barabási-Albert (BA) scale-free networks and Erdös-Rényi (ER) random networks. We show that, if natural frequencies of the oscillations are positively correlated with node degrees and the width of the frequency distribution is larger than a threshold value, a strong hysteresis loop arises in the synchronization diagram of BA networks, indicating the evidence of an explosive transition towards synchronization of relaxation oscillators system. In contrast to the results in BA networks, in more homogeneous ER networks, the synchronization transition is always of continuous type regardless of the width of the frequency distribution. Moreover, we consider the effect of degree-mixing patterns on the nature of the synchronization transition, and find that the degree assortativity is unfavorable for the occurrence of such an explosive transition.

  14. Explosive synchronization transitions in complex neural networks

    NASA Astrophysics Data System (ADS)

    Chen, Hanshuang; He, Gang; Huang, Feng; Shen, Chuansheng; Hou, Zhonghuai

    2013-09-01

    It has been recently reported that explosive synchronization transitions can take place in networks of phase oscillators [Gómez-Gardeñes et al. Phys. Rev. Lett. 106, 128701 (2011)] and chaotic oscillators [Leyva et al. Phys. Rev. Lett. 108, 168702 (2012)]. Here, we investigate the effect of a microscopic correlation between the dynamics and the interacting topology of coupled FitzHugh-Nagumo oscillators on phase synchronization transition in Barabási-Albert (BA) scale-free networks and Erdös-Rényi (ER) random networks. We show that, if natural frequencies of the oscillations are positively correlated with node degrees and the width of the frequency distribution is larger than a threshold value, a strong hysteresis loop arises in the synchronization diagram of BA networks, indicating the evidence of an explosive transition towards synchronization of relaxation oscillators system. In contrast to the results in BA networks, in more homogeneous ER networks, the synchronization transition is always of continuous type regardless of the width of the frequency distribution. Moreover, we consider the effect of degree-mixing patterns on the nature of the synchronization transition, and find that the degree assortativity is unfavorable for the occurrence of such an explosive transition.

  15. Ultra-Broad-Band Optical Parametric Amplifier or Oscillator

    NASA Technical Reports Server (NTRS)

    Strekalov, Dmitry; Matsko, Andrey; Savchenkov, Anatolly; Maleki, Lute

    2009-01-01

    A concept for an ultra-broad-band optical parametric amplifier or oscillator has emerged as a by-product of a theoretical study in fundamental quantum optics. The study was originally intended to address the question of whether the two-photon temporal correlation function of light [in particular, light produced by spontaneous parametric down conversion (SPDC)] can be considerably narrower than the inverse of the spectral width (bandwidth) of the light. The answer to the question was found to be negative. More specifically, on the basis of the universal integral relations between the quantum two-photon temporal correlation and the classical spectrum of light, it was found that the lower limit of two-photon correlation time is set approximately by the inverse of the bandwidth. The mathematical solution for the minimum two-photon correlation time also provides the minimum relative frequency dispersion of the down-converted light components; in turn, the minimum relative frequency dispersion translates to the maximum bandwidth, which is important for the design of an ultra-broad-band optical parametric oscillator or amplifier. In the study, results of an analysis of the general integral relations were applied in the case of an optically nonlinear, frequency-dispersive crystal in which SPDC produces collinear photons. Equations were found for the crystal orientation and pump wavelength, specific for each parametric-down-converting crystal, that eliminate the relative frequency dispersion of collinear degenerate (equal-frequency) signal and idler components up to the fourth order in the frequency-detuning parameter

  16. Theta and Alpha Oscillations Are Traveling Waves in the Human Neocortex.

    PubMed

    Zhang, Honghui; Watrous, Andrew J; Patel, Ansh; Jacobs, Joshua

    2018-06-01

    Human cognition requires the coordination of neural activity across widespread brain networks. Here, we describe a new mechanism for large-scale coordination in the human brain: traveling waves of theta and alpha oscillations. Examining direct brain recordings from neurosurgical patients performing a memory task, we found contiguous clusters of cortex in individual patients with oscillations at specific frequencies within 2 to 15 Hz. These oscillatory clusters displayed spatial phase gradients, indicating that they formed traveling waves that propagated at ∼0.25-0.75 m/s. Traveling waves were relevant behaviorally because their propagation correlated with task events and was more consistent when subjects performed the task well. Human traveling theta and alpha waves can be modeled by a network of coupled oscillators because the direction of wave propagation correlated with the spatial orientation of local frequency gradients. Our findings suggest that oscillations support brain connectivity by organizing neural processes across space and time. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. In vivo mouse inferior olive neurons exhibit heterogeneous subthreshold oscillations and spiking patterns

    PubMed Central

    Khosrovani, S.; Van Der Giessen, R. S.; De Zeeuw, C. I.; De Jeu, M. T. G.

    2007-01-01

    In vitro whole-cell recordings of the inferior olive have demonstrated that its neurons are electrotonically coupled and have a tendency to oscillate. However, it remains to be shown to what extent subthreshold oscillations do indeed occur in the inferior olive in vivo and whether its spatiotemporal firing pattern may be dynamically generated by including or excluding different types of oscillatory neurons. Here, we did whole-cell recordings of olivary neurons in vivo to investigate the relation between their subthreshold activities and their spiking behavior in an intact brain. The vast majority of neurons (85%) showed subthreshold oscillatory activities. The frequencies of these subthreshold oscillations were used to distinguish four main olivary subtypes by statistical means. Type I showed both sinusoidal subthreshold oscillations (SSTOs) and low-threshold Ca2+ oscillations (LTOs) (16%); type II showed only sinusoidal subthreshold oscillations (13%); type III showed only low-threshold Ca2+ oscillations (56%); and type IV did not reveal any subthreshold oscillations (15%). These subthreshold oscillation frequencies were strongly correlated with the frequencies of preferred spiking. The frequency characteristics of the subthreshold oscillations and spiking behavior of virtually all olivary neurons were stable throughout the recordings. However, the occurrence of spontaneous or evoked action potentials modified the subthreshold oscillation by resetting the phase of its peak toward 90°. Together, these findings indicate that the inferior olive in intact mammals offers a rich repertoire of different neurons with relatively stable frequency settings, which can be used to generate and reset temporal firing patterns in a dynamically coupled ensemble. PMID:17895389

  18. Low frequency oscillations in total ozone measurements

    NASA Technical Reports Server (NTRS)

    Gao, X. H.; Stanford, J. L.

    1989-01-01

    Low frequency oscillations with periods of approximately one to two months are found in eight years of global grids of total ozone data from the Total Ozone Mapping Spectrometer (TOMS) satellite instrument. The low frequency oscillations corroborate earlier analyses based on four years of data. In addition, both annual and seasonal one-point correlation maps based on the 8-year TOMS data are presented. The results clearly show a standing dipole in ozone perturbations, oscillating with 35 to 50 day periods over the equatorial Indian Ocean-west Pacific region. This contrasts with the eastward moving dipole reported in other data sets. The standing ozone dipole appears to be a dynamical feature associated with vertical atmospheric motions. Consistent with prior analyses based on lower stratospheric temperature fields, large-scale standing patterns are also found in the extratropics of both hemispheres, correlated with ozone fluctuations over the equatorial west Pacific. In the Northern Hemisphere, a standing pattern is observed extending from the tropical Indian Ocean to the north Pacific, across North America, and down to the equatorial Atlantic Ocean region. This feature is most pronounced in the NH summer.

  19. Timekeeping for the Space Technology 5 (ST-5) Mission

    NASA Technical Reports Server (NTRS)

    Raphael, Dave; Luers, Phil; Sank, Victor; Jackson, George

    2002-01-01

    Space Technology 5, or better known as ST-5, is a space technology development mission in the New Millennium Program (NMP) and NASA s first experiment in the design of miniaturized satellite constellations. The mission will design, integrate and launch multiple spacecraft into an orbit high above the Earth s protective magnetic field known as the magnetosphere. Each spacecraft incorporates innovative technology and constellation concepts which will be instrumental in future space science missions. A total of three ST-5 spacecraft will be launched as secondary payloads into a highly elliptical geo-synchronous transfer orbit, and will operate as a 3-element constellation for a minimum duration of 90 days. In order to correlate the time of science measurements with orbit position relative to the Earth, orbit position in space (with respect to other objects in space) and/or with events measured on Earth or other spacecraft, accurate knowledge of spacecraft and ground time is needed. Ground time as used in the USA (known as Universal Time Coordinated or UTC) is maintained by the U.S. Naval Observatory. Spacecraft time is maintained onboard within the Command and Data Handling (C&DH) system. The science requirements for ST-5 are that spacecraft time and ground time be correlatable to each other, with some degree of accuracy. Accurate knowledge of UTC time on a spacecraft is required so that science measurements can be correlated with orbit position relative to the Earth, orbit position in space and with events measured on Earth or other spacecraft. The most crucial parameter is not the clock oscillator frequency, but more importantly, how the clock oscillator frequency varies with time or temperature (clock oscillator drift). Even with an incorrect clock oscillator frequency, if there were no drift, the frequency could be assessed by comparing the spacecraft clock to a ground clock during a few correlation events. Once the frequency is accurately known, it is easy enough to make a regular adjustment to the spacecraft clock or to calculate the correct ground time for a given spacecraft clock time. The oscillator frequency, however, is temperature dependent, drifts with age and is affected by radiation; hence, repeated correlation measurements are required.

  20. Effect of wind tunnel acoustic modes on linear oscillating cascade aerodynamics

    NASA Technical Reports Server (NTRS)

    Buffum, Daniel H.; Fleeter, Sanford

    1993-01-01

    The aerodynamics of a biconvex airfoil cascade oscillating in torsion is investigated using the unsteady aerodynamic influence coefficient technique. For subsonic flow and reduced frequencies as large as 0.9, airfoil surface unsteady pressures resulting from oscillation of one of the airfoils are measured using flush-mounted high-frequency-response pressure transducers. The influence coefficient data are examined in detail and then used to predict the unsteady aerodynamics of a cascade oscillating at various interblade phase angles. These results are correlated with experimental data obtained in the traveling-wave mode of oscillation and linearized analysis predictions. It is found that the unsteady pressure disturbances created by an oscillating airfoil excite wind tunnel acoustic modes which have detrimental effects on the experimental data. Acoustic treatment is proposed to rectify this problem.

  1. Frequency modulation of neural oscillations according to visual task demands.

    PubMed

    Wutz, Andreas; Melcher, David; Samaha, Jason

    2018-02-06

    Temporal integration in visual perception is thought to occur within cycles of occipital alpha-band (8-12 Hz) oscillations. Successive stimuli may be integrated when they fall within the same alpha cycle and segregated for different alpha cycles. Consequently, the speed of alpha oscillations correlates with the temporal resolution of perception, such that lower alpha frequencies provide longer time windows for perceptual integration and higher alpha frequencies correspond to faster sampling and segregation. Can the brain's rhythmic activity be dynamically controlled to adjust its processing speed according to different visual task demands? We recorded magnetoencephalography (MEG) while participants switched between task instructions for temporal integration and segregation, holding stimuli and task difficulty constant. We found that the peak frequency of alpha oscillations decreased when visual task demands required temporal integration compared with segregation. Alpha frequency was strategically modulated immediately before and during stimulus processing, suggesting a preparatory top-down source of modulation. Its neural generators were located in occipital and inferotemporal cortex. The frequency modulation was specific to alpha oscillations and did not occur in the delta (1-3 Hz), theta (3-7 Hz), beta (15-30 Hz), or gamma (30-50 Hz) frequency range. These results show that alpha frequency is under top-down control to increase or decrease the temporal resolution of visual perception.

  2. Revealing plasma oscillation in THz spectrum from laser plasma of molecular jet.

    PubMed

    Li, Na; Bai, Ya; Miao, Tianshi; Liu, Peng; Li, Ruxin; Xu, Zhizhan

    2016-10-03

    Contribution of plasma oscillation to the broadband terahertz (THz) emission is revealed by interacting two-color (ω/2ω) laser pulses with a supersonic jet of nitrogen molecules. Temporal and spectral shifts of THz waves are observed as the plasma density varies. The former owes to the changing refractive index of the THz waves, and the latter correlates to the varying plasma frequency. Simulation of considering photocurrents, plasma oscillation and decaying plasma density explains the broadband THz spectrum and the varying THz spectrum. Plasma oscillation only contributes to THz waves at low plasma density owing to negligible plasma absorption. At the longer medium or higher density, the combining effects of plasma oscillation and absorption results in the observed low-frequency broadband THz spectra.

  3. Testing the relativistic precession model using low-frequency and kHz quasi-periodic oscillations in neutron star low-mass X-ray binaries with known spin

    NASA Astrophysics Data System (ADS)

    van Doesburgh, Marieke; van der Klis, Michiel

    2017-03-01

    We analyse all available RXTE data on a sample of 13 low-mass X-ray binaries with known neutron star spin that are not persistent pulsars. We carefully measure the correlations between the centroid frequencies of the quasi-periodic oscillations (QPOs). We compare these correlations to the prediction of the relativistic precession model that, due to frame dragging, a QPO will occur at the Lense-Thirring precession frequency νLT of a test-particle orbit whose orbital frequency is the upper kHz QPO frequency νu. Contrary to the most prominent previous studies, we find two different oscillations in the range predicted for νLT that are simultaneously present over a wide range of νu. Additionally, one of the low-frequency noise components evolves into a (third) QPO in the νLT range when νu exceeds 600 Hz. The frequencies of these QPOs all correlate to νu following power laws with indices between 0.4 and 3.3, significantly exceeding the predicted value of 2.0 in 80 per cent of the cases (at 3 to >20σ). Also, there is no evidence that the neutron star spin frequency affects any of these three QPO frequencies, as would be expected for frame dragging. Finally, the observed QPO frequencies tend to be higher than the νLT predicted for reasonable neutron star specific moment of inertia. In the light of recent successes of precession models in black holes, we briefly discuss ways in which such precession can occur in neutron stars at frequencies different from test-particle values and consistent with those observed. A precessing torus geometry and other torques than frame dragging may allow precession to produce the observed frequency correlations, but can only explain one of the three QPOs in the νLT range.

  4. Low-frequency oscillations in default mode subnetworks are associated with episodic memory impairments in Alzheimer's disease.

    PubMed

    Veldsman, Michele; Egorova, Natalia; Singh, Baljeet; Mungas, Dan; DeCarli, Charles; Brodtmann, Amy

    2017-11-01

    Disruptions to functional connectivity in subsystems of the default mode network are evident in Alzheimer's disease (AD). Functional connectivity estimates correlations in the time course of low-frequency activity. Much less is known about other potential perturbations to this activity, such as changes in the amplitude of oscillations and how this relates to cognition. We examined the amplitude of low-frequency fluctuations in 44 AD patients and 128 cognitively normal participants and related this to episodic memory, the core deficit in AD. We show higher amplitudes of low-frequency oscillations in AD patients. Rather than being compensatory, this appears to be maladaptive, with greater amplitude in the ventral default mode subnetwork associated with poorer episodic memory. Perturbations to default mode subnetworks in AD are evident in the amplitude of low-frequency oscillations in the resting brain. These disruptions are associated with episodic memory demonstrating their behavioral and clinical relevance in AD. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Identifying Wave-Particle Interactions in the Solar Wind using Statistical Correlations

    NASA Astrophysics Data System (ADS)

    Broiles, T. W.; Jian, L. K.; Gary, S. P.; Lepri, S. T.; Stevens, M. L.

    2017-12-01

    Heavy ions are a trace component of the solar wind, which can resonate with plasma waves, causing heating and acceleration relative to the bulk plasma. While wave-particle interactions are generally accepted as the cause of heavy ion heating and acceleration, observations to constrain the physics are lacking. In this work, we statistically link specific wave modes to heavy ion heating and acceleration. We have computed the Fast Fourier Transform (FFT) of transverse and compressional magnetic waves between 0 and 5.5 Hz using 9 days of ACE and Wind Magnetometer data. The FFTs are averaged over plasma measurement cycles to compute statistical correlations between magnetic wave power at each discrete frequency, and ion kinetic properties measured by ACE/SWICS and Wind/SWE. The results show that lower frequency transverse oscillations (< 0.2 Hz) and higher frequency compressional oscillations (> 0.4 Hz) are positively correlated with enhancements in the heavy ion thermal and drift speeds. Moreover, the correlation results for the He2+ and O6+ were similar on most days. The correlations were often weak, but most days had some frequencies that correlated with statistical significance. This work suggests that the solar wind heavy ions are possibly being heated and accelerated by both transverse and compressional waves at different frequencies.

  6. Long-range correlation of the membrane potential in neocortical neurons during slow oscillation

    PubMed Central

    Volgushev, Maxim; Chauvette, Sylvain; Timofeev, Igor

    2012-01-01

    Large amplitude slow waves are characteristic for the summary brain activity, recorded as electroencephalogram (EEG) or local field potentials (LFP), during deep stages of sleep and some types of anesthesia. Slow rhythm of the synchronized EEG reflects an alternation of active (depolarized, UP) and silent (hyperpolarized, DOWN) states of neocortical neurons. In neurons, involvement in the generalized slow oscillation results in a long-range synchronization of changes of their membrane potential as well as their firing. Here, we aimed at intracellular analysis of details of this synchronization. We asked which components of neuronal activity exhibit long-range correlations during the synchronized EEG? To answer this question, we made simultaneous intracellular recordings from two to four neocortical neurons in cat neocortex. We studied how correlated is the occurrence of active and silent states, and how correlated are fluctuations of the membrane potential in pairs of neurons located close one to the other or separated by up to 13 mm. We show that strong long-range correlation of the membrane potential was observed only (i) during the slow oscillation but not during periods without the oscillation, (ii) during periods which included transitions between the states but not during within-the-state periods, and (iii) for the low-frequency (<5 Hz) components of membrane potential fluctuations but not for the higher-frequency components (>10 Hz). In contrast to the neurons located several millimeters one from the other, membrane potential fluctuations in neighboring neurons remain strongly correlated during periods without slow oscillation. We conclude that membrane potential correlation in distant neurons is brought about by synchronous transitions between the states, while activity within the states is largely uncorrelated. The lack of the generalized fine-scale synchronization of membrane potential changes in neurons during the active states of slow oscillation may allow individual neurons to selectively engage in short living episodes of correlated activity—a process that may be similar to dynamical formation of neuronal ensembles during activated brain states. PMID:21854963

  7. Examining the neural correlates of depressive and motor symptoms in Parkinson's disease using Frequency Component Analysis (FCA)

    NASA Astrophysics Data System (ADS)

    Song, Xiaopeng; Hu, Xiao; Zhou, Shuqin; Liu, Weiguo; Liu, Yijun; Zhu, Huaiqiu; Gao, Jia-Hong

    2016-03-01

    Depression is prevalent among patients with Parkinson's disease (PD); however the pathophysiology of depression in PD is not well understood. In order to investigate how depression and motor impairments differentially and interactively affect specific brain regions in Parkinson's disease, we introduced a new data driven approach, namely Frequency Component Analysis (FCA), to decompose the resting-state functional magnetic resonance imaging data of 59 subjects with Parkinson's disease into different frequency bands. We then evaluated the main effects of motor severity and depression, and their interactive effects on the BOLD-fMRI signal oscillation energy in these specific frequency components. Our results show that the severity of motor symptoms is more negatively correlated with energy in the frequency band of 0.10-0.25Hz in the bilateral thalamus (THA), but more positively correlated with energy in the frequency band of 0.01-0.027Hz in the bilateral postcentral gyrus (PoCG). In contrast, the severity of depressive symptoms is more associated with the higher energy of the high frequency oscillations (>0.1Hz) but lower energy of 0.01-0.027Hz in the bilateral subgenual gyrus (SGC). Importantly, the interaction between motor and depressive symptoms is negatively correlated with the energy of high frequency oscillations (>0.1Hz) in the substantia nigra/ventral tegmental area (SN/VTA), left hippocampus (HIPP), left inferior orbital frontal cortex (OFC), and left temporoparietal junction (TPJ), but positively correlated with the energy of 0.02-0.05Hz in the left inferior OFC, left TPJ, left inferior temporal gyrus (ITG), and bilateral cerebellum. These results demonstrated that FCA was a promising method in interrogating the neurophysiological implications of different brain rhythms. Our findings further revealed the neural bases underlying the interactions as well the dissociations between motor and depressive symptoms in Parkinson's disease.

  8. Synchronization, non-linear dynamics and low-frequency fluctuations: Analogy between spontaneous brain activity and networked single-transistor chaotic oscillators

    PubMed Central

    Minati, Ludovico; Chiesa, Pietro; Tabarelli, Davide; D'Incerti, Ludovico

    2015-01-01

    In this paper, the topographical relationship between functional connectivity (intended as inter-regional synchronization), spectral and non-linear dynamical properties across cortical areas of the healthy human brain is considered. Based upon functional MRI acquisitions of spontaneous activity during wakeful idleness, node degree maps are determined by thresholding the temporal correlation coefficient among all voxel pairs. In addition, for individual voxel time-series, the relative amplitude of low-frequency fluctuations and the correlation dimension (D2), determined with respect to Fourier amplitude and value distribution matched surrogate data, are measured. Across cortical areas, high node degree is associated with a shift towards lower frequency activity and, compared to surrogate data, clearer saturation to a lower correlation dimension, suggesting presence of non-linear structure. An attempt to recapitulate this relationship in a network of single-transistor oscillators is made, based on a diffusive ring (n = 90) with added long-distance links defining four extended hub regions. Similarly to the brain data, it is found that oscillators in the hub regions generate signals with larger low-frequency cycle amplitude fluctuations and clearer saturation to a lower correlation dimension compared to surrogates. The effect emerges more markedly close to criticality. The homology observed between the two systems despite profound differences in scale, coupling mechanism and dynamics appears noteworthy. These experimental results motivate further investigation into the heterogeneity of cortical non-linear dynamics in relation to connectivity and underline the ability for small networks of single-transistor oscillators to recreate collective phenomena arising in much more complex biological systems, potentially representing a future platform for modelling disease-related changes. PMID:25833429

  9. Activity Parameters of Subthalamic Nucleus Neurons Selectively Predict Motor Symptom Severity in Parkinson's Disease

    PubMed Central

    Gulberti, Alessandro; Zittel, Simone; Tudor Jones, Adam A.; Fickel, Ulrich; Münchau, Alexander; Köppen, Johannes A.; Gerloff, Christian; Westphal, Manfred; Buhmann, Carsten; Hamel, Wolfgang; Engel, Andreas K.

    2014-01-01

    Parkinson's disease (PD) is a heterogeneous disorder that leads to variable expression of several different motor symptoms. While changes in firing rate, pattern, and oscillation of basal ganglia neurons have been observed in PD patients and experimental animals, there is limited evidence linking them to specific motor symptoms. Here we examined this relationship using extracellular recordings of subthalamic nucleus neurons from 19 PD patients undergoing surgery for deep brain stimulation. For each patient, ≥10 single units and/or multi-units were recorded in the OFF medication state. We correlated the proportion of neurons displaying different activities with preoperative Unified Parkinson's Disease Rating Scale subscores (OFF medication). The mean spectral power at sub-beta frequencies and percentage of units oscillating at beta frequencies were positively correlated with the axial and limb rigidity scores, respectively. The percentage of units oscillating at gamma frequency was negatively correlated with the bradykinesia scores. The mean intraburst rate was positively correlated with both bradykinesia and axial scores, while the related ratio of interspike intervals below/above 10 ms was positively correlated with these symptoms and limb rigidity. None of the activity parameters correlated with tremor. The grand average of all the significantly correlated subthalamic nucleus activities accounted for >60% of the variance of the combined bradykinetic-rigid and axial scores. Our results demonstrate that the occurrence of alterations in the rate and pattern of basal ganglia neurons could partly underlie the variability in parkinsonian phenotype. PMID:24790198

  10. Correlated disorder in the Kuramoto model: Effects on phase coherence, finite-size scaling, and dynamic fluctuations.

    PubMed

    Hong, Hyunsuk; O'Keeffe, Kevin P; Strogatz, Steven H

    2016-10-01

    We consider a mean-field model of coupled phase oscillators with quenched disorder in the natural frequencies and coupling strengths. A fraction p of oscillators are positively coupled, attracting all others, while the remaining fraction 1-p are negatively coupled, repelling all others. The frequencies and couplings are deterministically chosen in a manner which correlates them, thereby correlating the two types of disorder in the model. We first explore the effect of this correlation on the system's phase coherence. We find that there is a critical width γ c in the frequency distribution below which the system spontaneously synchronizes. Moreover, this γ c is independent of p. Hence, our model and the traditional Kuramoto model (recovered when p = 1) have the same critical width γ c . We next explore the critical behavior of the system by examining the finite-size scaling and the dynamic fluctuation of the traditional order parameter. We find that the model belongs to the same universality class as the Kuramoto model with deterministically (not randomly) chosen natural frequencies for the case of p < 1.

  11. Frequency comb generation in a continuously pumped optical parametric oscillator

    NASA Astrophysics Data System (ADS)

    Mosca, S.; Parisi, M.; Ricciardi, I.; Leo, F.; Hansson, T.; Erkintalo, M.; Maddaloni, P.; De Natale, P.; Wabnitz, S.; De Rosa, M.

    2018-02-01

    We demonstrate optical frequency comb generation in a continuously pumped optical parametric oscillator, in the parametric region around half of the pump frequency. We also model the dynamics of such quadratic combs using a single time-domain mean-field equation, and obtain simulation results that are in good agreement with experimentally observed spectra. Moreover, we numerically investigate the coherence properties of simulated combs, showing the existence of correlated and phase-locked combs. Our work could pave the way for a new class of frequency comb sources, which may enable straightforward access to new spectral regions and stimulate novel applications of frequency combs.

  12. [Multi-channel in vivo recording techniques: signal processing of action potentials and local field potentials].

    PubMed

    Xu, Jia-Min; Wang, Ce-Qun; Lin, Long-Nian

    2014-06-25

    Multi-channel in vivo recording techniques are used to record ensemble neuronal activity and local field potentials (LFP) simultaneously. One of the key points for the technique is how to process these two sets of recorded neural signals properly so that data accuracy can be assured. We intend to introduce data processing approaches for action potentials and LFP based on the original data collected through multi-channel recording system. Action potential signals are high-frequency signals, hence high sampling rate of 40 kHz is normally chosen for recording. Based on waveforms of extracellularly recorded action potentials, tetrode technology combining principal component analysis can be used to discriminate neuronal spiking signals from differently spatially distributed neurons, in order to obtain accurate single neuron spiking activity. LFPs are low-frequency signals (lower than 300 Hz), hence the sampling rate of 1 kHz is used for LFPs. Digital filtering is required for LFP analysis to isolate different frequency oscillations including theta oscillation (4-12 Hz), which is dominant in active exploration and rapid-eye-movement (REM) sleep, gamma oscillation (30-80 Hz), which is accompanied by theta oscillation during cognitive processing, and high frequency ripple oscillation (100-250 Hz) in awake immobility and slow wave sleep (SWS) state in rodent hippocampus. For the obtained signals, common data post-processing methods include inter-spike interval analysis, spike auto-correlation analysis, spike cross-correlation analysis, power spectral density analysis, and spectrogram analysis.

  13. Simultaneous EEG/fMRI analysis of the resonance phenomena in steady-state visual evoked responses.

    PubMed

    Bayram, Ali; Bayraktaroglu, Zubeyir; Karahan, Esin; Erdogan, Basri; Bilgic, Basar; Ozker, Muge; Kasikci, Itir; Duru, Adil D; Ademoglu, Ahmet; Oztürk, Cengizhan; Arikan, Kemal; Tarhan, Nevzat; Demiralp, Tamer

    2011-04-01

    The stability of the steady-state visual evoked potentials (SSVEPs) across trials and subjects makes them a suitable tool for the investigation of the visual system. The reproducible pattern of the frequency characteristics of SSVEPs shows a global amplitude maximum around 10 Hz and additional local maxima around 20 and 40 Hz, which have been argued to represent resonant behavior of damped neuronal oscillators. Simultaneous electroencephalogram/functional magnetic resonance imaging (EEG/fMRI) measurement allows testing of the resonance hypothesis about the frequency-selective increases in SSVEP amplitudes in human subjects, because the total synaptic activity that is represented in the fMRI-Blood Oxygen Level Dependent (fMRI-BOLD) response would not increase but get synchronized at the resonance frequency. For this purpose, 40 healthy volunteers were visually stimulated with flickering light at systematically varying frequencies between 6 and 46 Hz, and the correlations between SSVEP amplitudes and the BOLD responses were computed. The SSVEP frequency characteristics of all subjects showed 3 frequency ranges with an amplitude maximum in each of them, which roughly correspond to alpha, beta and gamma bands of the EEG. The correlation maps between BOLD responses and SSVEP amplitude changes across the different stimulation frequencies within each frequency band showed no significant correlation in the alpha range, while significant correlations were obtained in the primary visual area for the beta and gamma bands. This non-linear relationship between the surface recorded SSVEP amplitudes and the BOLD responses of the visual cortex at stimulation frequencies around the alpha band supports the view that a resonance at the tuning frequency of the thalamo-cortical alpha oscillator in the visual system is responsible for the global amplitude maximum of the SSVEP around 10 Hz. Information gained from the SSVEP/fMRI analyses in the present study might be extrapolated to the EEG/fMRI analysis of the transient event-related potentials (ERPs) in terms of expecting more reliable and consistent correlations between EEG and fMRI responses, when the analyses are carried out on evoked or induced oscillations (spectral perturbations) in separate frequency bands instead of the time-domain ERP peaks.

  14. Spectrally pure RF photonic source based on a resonant optical hyper-parametric oscillator

    NASA Astrophysics Data System (ADS)

    Liang, W.; Eliyahu, D.; Matsko, A. B.; Ilchenko, V. S.; Seidel, D.; Maleki, L.

    2014-03-01

    We demonstrate a free running 10 GHz microresonator-based RF photonic hyper-parametric oscillator characterized with phase noise better than -60 dBc/Hz at 10 Hz, -90 dBc/Hz at 100 Hz, and -150 dBc/Hz at 10 MHz. The device consumes less than 25 mW of optical power. A correlation between the frequency of the continuous wave laser pumping the nonlinear resonator and the generated RF frequency is confirmed. The performance of the device is compared with the performance of a standard optical fiber based coupled opto-electronic oscillator of OEwaves.

  15. Amplitude envelope correlations measure synchronous cortical oscillations in performing musicians.

    PubMed

    Zamm, Anna; Debener, Stefan; Bauer, Anna-Katharina R; Bleichner, Martin G; Demos, Alexander P; Palmer, Caroline

    2018-05-14

    A major question facing cognitive neuroscience is measurement of interbrain synchrony between individuals performing joint actions. We describe the application of a novel method for measuring musicians' interbrain synchrony: amplitude envelope correlations (AECs). Amplitude envelopes (AEs) reflect energy fluctuations in cortical oscillations over time; AE correlations measure the degree to which two envelope fluctuations are temporally correlated, such as cortical oscillations arising from two individuals performing a joint action. Wireless electroencephalography was recorded from two pianists performing a musical duet; an analysis pipeline is described for computing AEs of cortical oscillations at the duet performance frequency (number of tones produced per second) to test whether these oscillations reflect the temporal dynamics of partners' performances. The pianists' AE correlations were compared with correlations based on a distribution of AEs simulated from white noise signals using the same methods. The AE method was also applied to the temporal characteristics of the pianists' performances, to show that the observed pair's AEs reflect the temporal dynamics of their performance. AE correlations offer a promising approach for assessing interbrain correspondences in cortical activity associated with performing joint tasks. © 2018 New York Academy of Sciences.

  16. Role of local network oscillations in resting-state functional connectivity.

    PubMed

    Cabral, Joana; Hugues, Etienne; Sporns, Olaf; Deco, Gustavo

    2011-07-01

    Spatio-temporally organized low-frequency fluctuations (<0.1 Hz), observed in BOLD fMRI signal during rest, suggest the existence of underlying network dynamics that emerge spontaneously from intrinsic brain processes. Furthermore, significant correlations between distinct anatomical regions-or functional connectivity (FC)-have led to the identification of several widely distributed resting-state networks (RSNs). This slow dynamics seems to be highly structured by anatomical connectivity but the mechanism behind it and its relationship with neural activity, particularly in the gamma frequency range, remains largely unknown. Indeed, direct measurements of neuronal activity have revealed similar large-scale correlations, particularly in slow power fluctuations of local field potential gamma frequency range oscillations. To address these questions, we investigated neural dynamics in a large-scale model of the human brain's neural activity. A key ingredient of the model was a structural brain network defined by empirically derived long-range brain connectivity together with the corresponding conduction delays. A neural population, assumed to spontaneously oscillate in the gamma frequency range, was placed at each network node. When these oscillatory units are integrated in the network, they behave as weakly coupled oscillators. The time-delayed interaction between nodes is described by the Kuramoto model of phase oscillators, a biologically-based model of coupled oscillatory systems. For a realistic setting of axonal conduction speed, we show that time-delayed network interaction leads to the emergence of slow neural activity fluctuations, whose patterns correlate significantly with the empirically measured FC. The best agreement of the simulated FC with the empirically measured FC is found for a set of parameters where subsets of nodes tend to synchronize although the network is not globally synchronized. Inside such clusters, the simulated BOLD signal between nodes is found to be correlated, instantiating the empirically observed RSNs. Between clusters, patterns of positive and negative correlations are observed, as described in experimental studies. These results are found to be robust with respect to a biologically plausible range of model parameters. In conclusion, our model suggests how resting-state neural activity can originate from the interplay between the local neural dynamics and the large-scale structure of the brain. Copyright © 2011 Elsevier Inc. All rights reserved.

  17. Nusselt correlation to predict heat transfer from an oscillated vertical annular fluid column through a porous domain

    NASA Astrophysics Data System (ADS)

    Sayar, Ersin; Sari, Ugurcan

    2017-04-01

    Experimental evaluation of the heat transfer in oscillating flow under the constant heat flux and constant amplitude fluid displacement conditions is presented for a vertical annular flow through a stainless steel wool porous media. The analysis is carried out for two different heat fluxes and for five different frequencies. The data is acquired from the measurements both in the initial transient period and in the pseudo-steady (cyclic) period by the system. The physical and mathematical behavior of the resulting Nusselt numbers are analyzed, according to data acquired from the experiments and in accordance with the results of the Buckingham Pi theorem. A cycle and space averaged Nusselt number correlation is suggested as a function of kinetic Reynolds number for oscillating flows. The suggested correlation is useful in predicting heat transfer from oscillating flows through highly porous and permeable solid media at low actuation frequencies and at low heat fluxes applied in the wall. The validity of the Nusselt numbers acquired by correlation is discussed using experimental Nusselt numbers for the selected kinetic Reynolds number interval. The present investigation has possible applications in moderate sized wicked heat pipes, solid matrix compact heat exchangers compromising of metallic foams, filtration equipment, and steam generators.

  18. REPRODUCING THE CORRELATIONS OF TYPE C LOW-FREQUENCY QUASI-PERIODIC OSCILLATION PARAMETERS IN XTE J1550–564 WITH A SPIRAL STRUCTURE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Varniere, Peggy; Vincent, Frederic H., E-mail: varniere@apc.univ-paris7.fr

    While it has been observed that the parameters intrinsic to the type C low-frequency quasi-periodic oscillations are related in a nonlinear manner among themselves, there has been, up to now, no model to explain or reproduce how the frequency, the FWHM, and the rms amplitude of the type C low-frequency quasi-periodic oscillations behave with respect to one another. Here we are using a simple toy model representing the emission from a standard disk and a spiral such as that caused by the accretion–ejection instability to reproduce the overall observed behavior and shed some light on its origin. This allows usmore » to prove the ability of such a spiral structure to be at the origin of flux modulation over more than an order of magnitude in frequency.« less

  19. Investigation of low-frequency-oscillating water flow in metal foam with 10 pores per inch

    NASA Astrophysics Data System (ADS)

    Bağcı, Ö.; Arbak, A.; De Paepe, M.; Dukhan, N.

    2018-01-01

    In this study, oscillating water flow in metal foam with open cells is investigated experimentally. The metal foam sample has a porosity of 88% and 10 pores. The water was oscillated in the test section with three frequencies between 0.116 Hz and 0.348 Hz, which are considered low for water oscillation, and three flow displacements ranging between 74.35 mm and 111.53 mm. The combinations of frequencies of displacements were studied for their impacts of dimensional and non-dimensional pressure loss quantities. To this purpose, friction factor was correlated as a function of kinetic Reynolds number. The same metal foam sample was studied by exposing it to steady-state water flow to investigate its permeability and drag coefficient in low-velocity flow regimes. The friction factor distribution for oscillating flow was found to be over that found for steady state. The outcomes of the study are important for studying heat transfer under the same flow conditions.

  20. Experimental development of a Nusselt correlation for forced reciprocating oscillated vertical annular glycerol flow through a porous domain

    NASA Astrophysics Data System (ADS)

    Sayar, Ersin

    2017-07-01

    The objective of this paper is to investigate the heat transfer to oscillating annular flow of a viscous fluid. The flow media includes stationary stainless steel wool porous domain and glycerol as the working fluid. The effects of actuation frequency and wall heat flux on the temperature field and resultant heat convection coefficient are studied. The temperature values at radial direction are close each other as porous media mixes the glycerol successfully. A correlation with a functional dependence to kinetic Reynolds number is recommended that can be used to acquire the averaged heat transfer for oscillating flows. Present experimental results with glycerol in a porous media are compared to the published experimental works with water. For the limited case of the two working fluids, Nusselt number is normalized well using the Prandtl number (Pr0.67). Results are also compared to non-porous media study and heat transfer is found to increase up to a factor of five in porous media. The recommended correlation is claimed to have a significant role for anticipating heat transfer of oscillating viscous fluid not only at low frequencies but also at low heat fluxes in a porous and permeable solid media.

  1. Altered modulation of gamma oscillation frequency by speed of visual motion in children with autism spectrum disorders.

    PubMed

    Stroganova, Tatiana A; Butorina, Anna V; Sysoeva, Olga V; Prokofyev, Andrey O; Nikolaeva, Anastasia Yu; Tsetlin, Marina M; Orekhova, Elena V

    2015-01-01

    Recent studies link autism spectrum disorders (ASD) with an altered balance between excitation and inhibition (E/I balance) in cortical networks. The brain oscillations in high gamma-band (50-120 Hz) are sensitive to the E/I balance and may appear useful biomarkers of certain ASD subtypes. The frequency of gamma oscillations is mediated by level of excitation of the fast-spiking inhibitory basket cells recruited by increasing strength of excitatory input. Therefore, the experimental manipulations affecting gamma frequency may throw light on inhibitory networks dysfunction in ASD. Here, we used magnetoencephalography (MEG) to investigate modulation of visual gamma oscillation frequency by speed of drifting annular gratings (1.2, 3.6, 6.0 °/s) in 21 boys with ASD and 26 typically developing boys aged 7-15 years. Multitaper method was used for analysis of spectra of gamma power change upon stimulus presentation and permutation test was applied for statistical comparisons. We also assessed in our participants visual orientation discrimination thresholds, which are thought to depend on excitability of inhibitory networks in the visual cortex. Although frequency of the oscillatory gamma response increased with increasing velocity of visual motion in both groups of participants, the velocity effect was reduced in a substantial proportion of children with ASD. The range of velocity-related gamma frequency modulation correlated inversely with the ability to discriminate oblique line orientation in the ASD group, while no such correlation has been observed in the group of typically developing participants. Our findings suggest that abnormal velocity-related gamma frequency modulation in ASD may constitute a potential biomarker for reduced excitability of fast-spiking inhibitory neurons in a subset of children with ASD.

  2. Quantum correlations in microwave frequency combs

    NASA Astrophysics Data System (ADS)

    Weissl, Thomas; Jolin, Shan W.; Haviland, David B.; Department of Applied Physics Team

    Non-linear superconducting resonators are used as parametric amplifiers in circuit quantum electrodynamics experiments. When a strong pump is applied to a non-linear microwave oscillator, it correlates vacuum fluctuations at signal and idler frequencies symmetrically located around the pump, resulting in two-mode squeezed vacuum. When the non-linear oscillator is pumped with a frequency comb, complex multipartite entangled states can be created as demonstrated with experiments in the optical domain. Such cluster states are considered to be a universal resource for one-way quantum computing. With our microwave measurement setup it is possible to pump and measure response at as many as 42 frequencies in parallel, with independent control over all pump amplitudes and phases. We show results of two-mode squeezing for of pairs of tones in a microwave frequency comb. The squeezing is created by four-wave mixing of a pump tone applied to a non-linear coplanar-waveguide resonator. We acknowledge financial support from the Knut and Alice Wallenberg foundation.

  3. Subthalamic nucleus phase–amplitude coupling correlates with motor impairment in Parkinson’s disease

    PubMed Central

    van Wijk, Bernadette C.M.; Beudel, Martijn; Jha, Ashwani; Oswal, Ashwini; Foltynie, Tom; Hariz, Marwan I.; Limousin, Patricia; Zrinzo, Ludvic; Aziz, Tipu Z.; Green, Alexander L.; Brown, Peter; Litvak, Vladimir

    2016-01-01

    Objective High-amplitude beta band oscillations within the subthalamic nucleus are frequently associated with Parkinson’s disease but it is unclear how they might lead to motor impairments. Here we investigate a likely pathological coupling between the phase of beta band oscillations and the amplitude of high-frequency oscillations around 300 Hz. Methods We analysed an extensive data set comprising resting-state recordings obtained from deep brain stimulation electrodes in 33 patients before and/or after taking dopaminergic medication. We correlated mean values of spectral power and phase–amplitude coupling with severity of hemibody bradykinesia/rigidity. In addition, we used simultaneously recorded magnetoencephalography to look at functional interactions between the subthalamic nucleus and ipsilateral motor cortex. Results Beta band power and phase–amplitude coupling within the subthalamic nucleus correlated positively with severity of motor impairment. This effect was more pronounced within the low-beta range, whilst coherence between subthalamic nucleus and motor cortex was dominant in the high-beta range. Conclusions We speculate that the beta band might impede pro-kinetic high-frequency activity patterns when phase–amplitude coupling is prominent. Furthermore, results provide evidence for a functional subdivision of the beta band into low and high frequencies. Significance Our findings contribute to the interpretation of oscillatory activity within the cortico-basal ganglia circuit. PMID:26971483

  4. Determination of Atomic and Molecular Excited-State Lifetimes Using an Opto-electronic Cross-Correlation Method.

    DTIC Science & Technology

    1981-10-07

    new instrument (cf. Fig. 1) is simply a four - quadrant ring-diode multi- 5 plier (Fig. 2). The reference frequency (RF) and local oscillator (LO) inputs...movement, and scan speed of the corner-cube. Other Components. A rotating-sector chopper modulates the laser pulse train at a frequency of approximately 50...the cross-correlation experiment. In this application, the detection bandpass is simply displaced from DC to the chopper frequency; problems arising

  5. Energy Spectra and High Frequency Oscillations in 4U 0614+091

    NASA Technical Reports Server (NTRS)

    Ford, E. C.; Kaaret, P.; Chen, K.; Tavani, M.; Barret, D.; Bloser, P.; Grindlay, J.; Harmon, B. A.; Paciesas, W. S.; Zhang, S. N.

    1997-01-01

    We investigate the behavior of the high frequency quasi-periodic oscillations (QPOs) in 4U 0614+091, combining timing and spectral analysis of RXTE (Rossi X-ray Timing Explorer) observations. The energy spectrum of the source can be described by a power law plus a blackbody component. The blackbody has a variable temperature (kT approximately 0.8 to 1.4 keV) and accounts for 10 to 25% of the total energy flux. The power law flux and photon index also vary (F approximately 0.8 to 1.6 x 10(exp -9) erg/sq cm.s and alpha approximately 2.0 to 2.8 respectively). We find a robust correlation of the frequency of the higher frequency QPO with the flux of the blackbody. The source follows the same relation even in observations separated by several months. The QPO frequency does not have a similarly unique correlation with the total flux or the flux of the power law component. The RMS amplitudes of the higher frequency QPO rise with energy but are consistent with a constant for the lower frequency QPO. These results may be interpreted in terms of a beat frequency model for the production of the high frequency QPOs.

  6. Synchronization, non-linear dynamics and low-frequency fluctuations: Analogy between spontaneous brain activity and networked single-transistor chaotic oscillators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Minati, Ludovico, E-mail: lminati@ieee.org, E-mail: ludovico.minati@unitn.it, E-mail: lminati@istituto-besta.it; Center for Mind/Brain Sciences, University of Trento, Trento; Chiesa, Pietro

    In this paper, the topographical relationship between functional connectivity (intended as inter-regional synchronization), spectral and non-linear dynamical properties across cortical areas of the healthy human brain is considered. Based upon functional MRI acquisitions of spontaneous activity during wakeful idleness, node degree maps are determined by thresholding the temporal correlation coefficient among all voxel pairs. In addition, for individual voxel time-series, the relative amplitude of low-frequency fluctuations and the correlation dimension (D{sub 2}), determined with respect to Fourier amplitude and value distribution matched surrogate data, are measured. Across cortical areas, high node degree is associated with a shift towards lower frequencymore » activity and, compared to surrogate data, clearer saturation to a lower correlation dimension, suggesting presence of non-linear structure. An attempt to recapitulate this relationship in a network of single-transistor oscillators is made, based on a diffusive ring (n = 90) with added long-distance links defining four extended hub regions. Similarly to the brain data, it is found that oscillators in the hub regions generate signals with larger low-frequency cycle amplitude fluctuations and clearer saturation to a lower correlation dimension compared to surrogates. The effect emerges more markedly close to criticality. The homology observed between the two systems despite profound differences in scale, coupling mechanism and dynamics appears noteworthy. These experimental results motivate further investigation into the heterogeneity of cortical non-linear dynamics in relation to connectivity and underline the ability for small networks of single-transistor oscillators to recreate collective phenomena arising in much more complex biological systems, potentially representing a future platform for modelling disease-related changes.« less

  7. Role of the Ionosphere in the Generation of Large-Amplitude Ulf Waves at High Latitudes

    NASA Astrophysics Data System (ADS)

    Tulegenov, B.; Guido, T.; Streltsov, A. V.

    2014-12-01

    We present results from the statistical study of ULF waves detected by the fluxgate magnetometer in Gakona, Alaska during several experimental campaigns conducted at the High Frequency Active Auroral Research Program (HAARP) facility in years 2011-2013. We analyzed frequencies of ULF waves recorded during 26 strongly disturbed geomagnetic events (substorms) and compared them with frequencies of ULF waves detected during magnetically quite times. Our analysis demonstrates that the frequency of the waves carrying most of the power almost in all these events is less than 1 mHz. We also analyzed data from the ACE satellite, measuring parameters of the solar wind in the L1 Lagrangian point between Earth and Sun, and found that in several occasions there is a strong correlation between oscillations of the magnetic field in the solar wind and oscillations detected on the ground. We also found several cases when there is no correlation between signals detected on ACE and on the ground. This finding suggests that these frequencies correspond to the fundamental eigenfrequency of the coupled magnetosphere-ionosphere system. The low frequency of the oscillations is explained by the effect of the ionosphere, where the current is carried by ions through highly collisional media. The amplitude of these waves can reach significant magnitude when the system is driven by the external driver (for example, the solar wind) with this particular frequency. When the frequency of the driver does not match the frequency of the system, the waves still are observed, but their amplitudes are much smaller.

  8. Alpha-Band Rhythms in Visual Task Performance: Phase-Locking by Rhythmic Sensory Stimulation

    PubMed Central

    de Graaf, Tom A.; Gross, Joachim; Paterson, Gavin; Rusch, Tessa; Sack, Alexander T.; Thut, Gregor

    2013-01-01

    Oscillations are an important aspect of neuronal activity. Interestingly, oscillatory patterns are also observed in behaviour, such as in visual performance measures after the presentation of a brief sensory event in the visual or another modality. These oscillations in visual performance cycle at the typical frequencies of brain rhythms, suggesting that perception may be closely linked to brain oscillations. We here investigated this link for a prominent rhythm of the visual system (the alpha-rhythm, 8–12 Hz) by applying rhythmic visual stimulation at alpha-frequency (10.6 Hz), known to lead to a resonance response in visual areas, and testing its effects on subsequent visual target discrimination. Our data show that rhythmic visual stimulation at 10.6 Hz: 1) has specific behavioral consequences, relative to stimulation at control frequencies (3.9 Hz, 7.1 Hz, 14.2 Hz), and 2) leads to alpha-band oscillations in visual performance measures, that 3) correlate in precise frequency across individuals with resting alpha-rhythms recorded over parieto-occipital areas. The most parsimonious explanation for these three findings is entrainment (phase-locking) of ongoing perceptually relevant alpha-band brain oscillations by rhythmic sensory events. These findings are in line with occipital alpha-oscillations underlying periodicity in visual performance, and suggest that rhythmic stimulation at frequencies of intrinsic brain-rhythms can be used to reveal influences of these rhythms on task performance to study their functional roles. PMID:23555873

  9. Large-scale cortical correlation structure of spontaneous oscillatory activity

    PubMed Central

    Hipp, Joerg F.; Hawellek, David J.; Corbetta, Maurizio; Siegel, Markus; Engel, Andreas K.

    2013-01-01

    Little is known about the brain-wide correlation of electrophysiological signals. Here we show that spontaneous oscillatory neuronal activity exhibits frequency-specific spatial correlation structure in the human brain. We developed an analysis approach that discounts spurious correlation of signal power caused by the limited spatial resolution of electrophysiological measures. We applied this approach to source estimates of spontaneous neuronal activity reconstructed from magnetoencephalography (MEG). Overall, correlation of power across cortical regions was strongest in the alpha to beta frequency range (8–32 Hz) and correlation patterns depended on the underlying oscillation frequency. Global hubs resided in the medial temporal lobe in the theta frequency range (4–6 Hz), in lateral parietal areas in the alpha to beta frequency range (8–23 Hz), and in sensorimotor areas for higher frequencies (32–45 Hz). Our data suggest that interactions in various large-scale cortical networks may be reflected in frequency specific power-envelope correlations. PMID:22561454

  10. Resting state cortical oscillations of patients with Parkinson disease and with and without subthalamic deep brain stimulation: a magnetoencephalography study.

    PubMed

    Cao, Chunyan; Li, Dianyou; Jiang, Tianxiao; Ince, Nuri Firat; Zhan, Shikun; Zhang, Jing; Sha, Zhiyi; Sun, Bomin

    2015-04-01

    In this study, we investigate the modification to cortical oscillations of patients with Parkinson disease (PD) by subthalamic deep brain stimulation (STN-DBS). Spontaneous cortical oscillations of patients with PD were recorded with magnetoencephalography during on and off subthalamic nucleus deep brain stimulation states. Several features such as average frequency, average power, and relative subband power in regions of interest were extracted in the frequency domain, and these features were correlated with Unified Parkinson Disease Rating Scale III evaluation. The same features were also investigated in patients with PD without surgery and healthy controls. Patients with Parkinson disease without surgery compared with healthy controls had a significantly lower average frequency and an increased average power in 1 to 48 Hz range in whole cortex. Higher relative power in theta and simultaneous decrease in beta and gamma over temporal and occipital were also observed in patients with PD. The Unified Parkinson Disease Rating Scale III rigidity score correlated with the average frequency and with the relative power of beta and gamma in frontal areas. During subthalamic nucleus deep brain stimulation, the average frequency increased significantly when stimulation was on compared with off state. In addition, the relative power dropped in delta, whereas it rose in beta over the whole cortex. Through the course of stimulation, the Unified Parkinson Disease Rating Scale III rigidity and tremor scores correlated with the relative power of alpha over left parietal. Subthalamic nucleus deep brain stimulation improves the symptoms of PD by suppressing the synchronization of alpha rhythm in somatomotor region.

  11. Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives.

    PubMed

    Brötzner, Christina P; Klimesch, Wolfgang; Doppelmayr, Michael; Zauner, Andrea; Kerschbaum, Hubert H

    2014-08-19

    Ongoing intrinsic brain activity in resting, but awake humans is dominated by alpha oscillations. In human, individual alpha frequency (IAF) is associated with cognitive performance. Noticeable, performance in cognitive and emotional tasks in women is associated with menstrual cycle phase and sex hormone levels, respectively. In the present study, we correlated frequency of alpha oscillation in resting women with menstrual cycle phase, sex hormone level, or use of oral contraceptives. Electroencephalogram (EEG) was recorded from 57 women (aged 24.07 ± 3.67 years) having a natural menstrual cycle as well as from 57 women (aged 22.37 ± 2.20 years) using oral contraceptives while they sat in an armchair with eyes closed. Alpha frequency was related to the menstrual cycle phase. Luteal women showed highest and late follicular women showed lowest IAF or center frequency. Furthermore, IAF as well as center frequency correlated negatively with endogenous estradiol level, but did not reveal an association with endogenous progesterone. Women using oral contraceptives showed an alpha frequency similar to women in the early follicular phase. We suggest that endogenous estradiol modulate resting alpha frequency. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  12. FREQUENCY SHIFTS OF RESONANT MODES OF THE SUN DUE TO NEAR-SURFACE CONVECTIVE SCATTERING

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhattacharya, J.; Hanasoge, S.; Antia, H. M.

    Measurements of oscillation frequencies of the Sun and stars can provide important independent constraints on their internal structure and dynamics. Seismic models of these oscillations are used to connect structure and rotation of the star to its resonant frequencies, which are then compared with observations, the goal being that of minimizing the difference between the two. Even in the case of the Sun, for which structure models are highly tuned, observed frequencies show systematic deviations from modeled frequencies, a phenomenon referred to as the “surface term.” The dominant source of this systematic effect is thought to be vigorous near-surface convection,more » which is not well accounted for in both stellar modeling and mode-oscillation physics. Here we bring to bear the method of homogenization, applicable in the asymptotic limit of large wavelengths (in comparison to the correlation scale of convection), to characterize the effect of small-scale surface convection on resonant-mode frequencies in the Sun. We show that the full oscillation equations, in the presence of temporally stationary three-dimensional (3D) flows, can be reduced to an effective “quiet-Sun” wave equation with altered sound speed, Brünt–Väisäla frequency, and Lamb frequency. We derive the modified equation and relations for the appropriate averaging of 3D flows and thermal quantities to obtain the properties of this effective medium. Using flows obtained from 3D numerical simulations of near-surface convection, we quantify their effect on solar oscillation frequencies and find that they are shifted systematically and substantially. We argue therefore that consistent interpretations of resonant frequencies must include modifications to the wave equation that effectively capture the impact of vigorous hydrodynamic convection.« less

  13. Resonant Thermalization of Periodically Driven Strongly Correlated Electrons

    NASA Astrophysics Data System (ADS)

    Peronaci, Francesco; Schiró, Marco; Parcollet, Olivier

    2018-05-01

    We study the dynamics of the Fermi-Hubbard model driven by a time-periodic modulation of the interaction within nonequilibrium dynamical mean-field theory. For moderate interaction, we find clear evidence of thermalization to a genuine infinite-temperature state with no residual oscillations. Quite differently, in the strongly correlated regime, we find a quasistationary extremely long-lived state with oscillations synchronized with the drive (Floquet prethermalization). Remarkably, the nature of this state dramatically changes upon tuning the drive frequency. In particular, we show the existence of a critical frequency at which the system rapidly thermalizes despite the large interaction. We characterize this resonant thermalization and provide an analytical understanding in terms of a breakdown of the periodic Schrieffer-Wolff transformation.

  14. Theta frequency decreases throughout the hippocampal formation in a focal epilepsy model.

    PubMed

    Kilias, Antje; Häussler, Ute; Heining, Katharina; Froriep, Ulrich P; Haas, Carola A; Egert, Ulrich

    2018-06-01

    Mesial temporal lobe epilepsy is characterized by focal, recurrent spontaneous seizures, sclerosis and granule cell dispersion (GCD) in the hippocampal formation. Changes in theta rhythm properties have been correlated with the severity of hippocampal restructuring and were suggested as a cause of memory deficits accompanying epilepsy. For severe sclerosis, it has even been questioned whether theta band oscillations persist. We asked how theta oscillations change with graded restructuring along the longitudinal hippocampal axis and whether these changes correlate with the overall severity of temporal lobe epilepsy. We recorded local field potentials in the medial entorhinal cortex and along the septo-temporal axis of the dentate gyrus at sites with different degrees of GCD in freely behaving epileptic mice. Theta frequency was decreased at all recording positions throughout the dentate gyrus and in the medial entorhinal cortex, irrespective of the extent of GCD or the rate of severe epileptic events. The frequency reduction by up to 1.7 Hz, corresponding to 1/3 octaves within the theta range, was present during rest, exploration and running. Despite the frequency reduction, theta oscillations remained coherent across the hippocampal formation and were modulated by running speed as in controls. The reduction in theta frequency thus is likely not a consequence of the local restructuring but rather a global phenomenon affecting the hippocampal formation as a whole. © 2018 Wiley Periodicals, Inc.

  15. Development of structural correlations and synchronization from adaptive rewiring in networks of Kuramoto oscillators

    NASA Astrophysics Data System (ADS)

    Papadopoulos, Lia; Kim, Jason Z.; Kurths, Jürgen; Bassett, Danielle S.

    2017-07-01

    Synchronization of non-identical oscillators coupled through complex networks is an important example of collective behavior, and it is interesting to ask how the structural organization of network interactions influences this process. Several studies have explored and uncovered optimal topologies for synchronization by making purposeful alterations to a network. On the other hand, the connectivity patterns of many natural systems are often not static, but are rather modulated over time according to their dynamics. However, this co-evolution and the extent to which the dynamics of the individual units can shape the organization of the network itself are less well understood. Here, we study initially randomly connected but locally adaptive networks of Kuramoto oscillators. In particular, the system employs a co-evolutionary rewiring strategy that depends only on the instantaneous, pairwise phase differences of neighboring oscillators, and that conserves the total number of edges, allowing the effects of local reorganization to be isolated. We find that a simple rule—which preserves connections between more out-of-phase oscillators while rewiring connections between more in-phase oscillators—can cause initially disordered networks to organize into more structured topologies that support enhanced synchronization dynamics. We examine how this process unfolds over time, finding a dependence on the intrinsic frequencies of the oscillators, the global coupling, and the network density, in terms of how the adaptive mechanism reorganizes the network and influences the dynamics. Importantly, for large enough coupling and after sufficient adaptation, the resulting networks exhibit interesting characteristics, including degree-frequency and frequency-neighbor frequency correlations. These properties have previously been associated with optimal synchronization or explosive transitions in which the networks were constructed using global information. On the contrary, by considering a time-dependent interplay between structure and dynamics, this work offers a mechanism through which emergent phenomena and organization can arise in complex systems utilizing local rules.

  16. Investigation of oscillating cascade aerodynamics by an experimental influence coefficient technique

    NASA Technical Reports Server (NTRS)

    Buffum, Daniel H.; Fleeter, Sanford

    1988-01-01

    Fundamental experiments are performed in the NASA Lewis Transonic Oscillating Cascade Facility to investigate the torsion mode unsteady aerodynamics of a biconvex airfoil cascade at realistic values of the reduced frequency for all interblade phase angles at a specified mean flow condition. In particular, an unsteady aerodynamic influence coefficient technique is developed and utilized in which only one airfoil in the cascade is oscillated at a time and the resulting airfoil surface unsteady pressure distribution measured on one dynamically instrumented airfoil. The unsteady aerodynamics of an equivalent cascade with all airfoils oscillating at a specified interblade phase angle are then determined through a vector summation of these data. These influence coefficient determined oscillation cascade data are correlated with data obtained in this cascade with all airfoils oscillating at several interblade phase angle values. The influence coefficients are then utilized to determine the unsteady aerodynamics of the cascade for all interblade phase angles, with these unique data subsequently correlated with predictions from a linearized unsteady cascade model.

  17. Chemical event chain model of coupled genetic oscillators.

    PubMed

    Jörg, David J; Morelli, Luis G; Jülicher, Frank

    2018-03-01

    We introduce a stochastic model of coupled genetic oscillators in which chains of chemical events involved in gene regulation and expression are represented as sequences of Poisson processes. We characterize steady states by their frequency, their quality factor, and their synchrony by the oscillator cross correlation. The steady state is determined by coupling and exhibits stochastic transitions between different modes. The interplay of stochasticity and nonlinearity leads to isolated regions in parameter space in which the coupled system works best as a biological pacemaker. Key features of the stochastic oscillations can be captured by an effective model for phase oscillators that are coupled by signals with distributed delays.

  18. Chemical event chain model of coupled genetic oscillators

    NASA Astrophysics Data System (ADS)

    Jörg, David J.; Morelli, Luis G.; Jülicher, Frank

    2018-03-01

    We introduce a stochastic model of coupled genetic oscillators in which chains of chemical events involved in gene regulation and expression are represented as sequences of Poisson processes. We characterize steady states by their frequency, their quality factor, and their synchrony by the oscillator cross correlation. The steady state is determined by coupling and exhibits stochastic transitions between different modes. The interplay of stochasticity and nonlinearity leads to isolated regions in parameter space in which the coupled system works best as a biological pacemaker. Key features of the stochastic oscillations can be captured by an effective model for phase oscillators that are coupled by signals with distributed delays.

  19. Enhanced detection of a low-frequency signal by using broad squeezed light and a bichromatic local oscillator

    NASA Astrophysics Data System (ADS)

    Li, Wei; Jin, Yuanbin; Yu, Xudong; Zhang, Jing

    2017-08-01

    We experimentally study a protocol of using the broadband high-frequency squeezed vacuum to detect the low-frequency signal. In this scheme, the lower sideband field of the squeezed light carries the low-frequency modulation signal, and the two strong coherent light fields are applied as the bichromatic local oscillator in the homodyne detection to measure the quantum entanglement of the upper and lower sideband for the broadband squeezed light. The power of one of the local oscillators for detecting the upper sideband can be adjusted to optimize the conditional variance in the low-frequency regime by subtracting the photocurrent of the upper sideband field of the squeezed light from that of the lower sideband field. By means of the quantum correlation of the upper and lower sideband for the broadband squeezed light, the low-frequency signal beyond the standard quantum limit is measured. This scheme is appropriate for enhancing the sensitivity of the low-frequency signal by the aid of the broad squeezed light, such as gravitational waves detection, and does not need to directly produce the low-frequency squeezing in an optical parametric process.

  20. Cross-correlated and oscillatory visual responses of superficial-layer and tecto-reticular neurones in cat superior colliculus.

    PubMed

    Chabli, A; Guitton, D; Fortin, S; Molotchnikoff, S

    2000-03-01

    The present study examined, in the superior colliculus (SC) of anaesthetised cats, the functional connectivity between superficial-layer neurones (SLNs) and tectoreticular neurones (TRNs: collicular output cells). TRNs were antidromically identified by electrical stimulation of the predorsal bundle. The auto- and cross-correlation histograms of visual responses of both types of neurones were recorded and analysed. A delayed, sharp peak in cross-correlograms allowed us to verify whether SLN and TRN cells were coupled; in addition, oscillatory activities were compared to verify if rhythmic responses of SLN sites were transmitted to TRN sites. We found that oscillatory activity was rarely observed in spontaneous activity of superficial (1/74) and TRN sites (1/48). Moving light bars induced oscillation in 31% (23/74) of the superficial-layer and in 23% (11/48) of the TRN sites. The strength of the rhythmic responses was determined by specific ranges of stimulus velocity in 83% (19/23) and 64% (7/11) of oscillating SLN and TRN sites, respectively. Frequencies of oscillations ranged between 5 and 125 Hz and were confined, for 53% of the cells, to the 5-20 Hz band. Thus, the band-width of frequencies of the stimulus-related oscillations in the superior colliculus was broader than the gamma range. Analysis of cross-correlation histograms revealed a significant predominant peak with a mean delay of 2.7+/-0.9 ms in 46% (17/37) of SLN-TRN pairs. Most correlated SLN-TRN pairs (88%: 15/17) had superimposed receptive fields, suggesting they were functionally interconnected. However, individual oscillatory frequencies of correlated and oscillatory SLN and TRN cells were never the same (0/8). Together, these results suggest that the neurones in collicular superficial layer contact TRNs and, consequently, support the idea that the superficial layers contribute to collicular outputs producing eye- and head-orienting movements.

  1. Comparing Optical Oscillators across the Air to Milliradians in Phase and 10^{-17} in Frequency.

    PubMed

    Sinclair, Laura C; Bergeron, Hugo; Swann, William C; Baumann, Esther; Deschênes, Jean-Daniel; Newbury, Nathan R

    2018-02-02

    We demonstrate carrier-phase optical two-way time-frequency transfer (carrier-phase OTWTFT) through the two-way exchange of frequency comb pulses. Carrier-phase OTWTFT achieves frequency comparisons with a residual instability of 1.2×10^{-17} at 1 s across a turbulent 4-km free space link, surpassing previous OTWTFT by 10-20 times and enabling future high-precision optical clock networks. Furthermore, by exploiting the carrier phase, this approach is able to continuously track changes in the relative optical phase of distant optical oscillators to 9 mrad (7 as) at 1 s averaging, effectively extending optical phase coherence over a broad spatial network for applications such as correlated spectroscopy between distant atomic clocks.

  2. CORRELATIONS IN HORIZONTAL BRANCH OSCILLATIONS AND BREAK COMPONENTS IN XTE J1701-462 AND GX 17+2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bu, Qing-cui; Chen, Li; Zhang, Liang

    2015-01-20

    We studied the horizontal branch oscillations (HBO) and the band-limited components observed in the power spectra of the transient neutron star low-mass X-ray binary XTE J1701-462 and the persistent ''Sco-like'' Z source GX 17+2. These two components were studied based on the state-resolved spectra. We found that the frequencies of XTE J1701-462 lie on the known correlations (WK and PBK), showing consistency with other types of X-ray binaries (black holes, atoll sources, and millisecond X-ray pulsars). However, GX 17+2 is shifted from the WK correlation like other typical Z sources. We suggest that the WK/PBK main track forms a boundarymore » that separates persistent sources from transient sources. The characteristic frequencies of break and HBO are independent of accretion rate in both sources, though it depends on spectral models. We also report the energy dependence of the HBO and break frequencies in XTE J1701-462 and how the temporal properties change with spectral state in XTE J1701-462 and GX 17+2. We studied the correlation between rms at the break and the HBO frequency. We suggest that HBO and break components for both sources probably arise from a similar physical mechanism: Comptonization emission from the corona. These two components could be caused by the same kind of oscillation in a corona with uneven density, and they could be generated from different areas of the corona. We further suggest that different proportions of the Comptonization component in the total flux cause the different distribution between GX 17+2 and XTE J1701-462 in the rms{sub break}-rms{sub HBO} diagram.« less

  3. Nonrandom variability in respiratory cycle parameters of humans during stage 2 sleep.

    PubMed

    Modarreszadeh, M; Bruce, E N; Gothe, B

    1990-08-01

    We analyzed breath-to-breath inspiratory time (TI), expiratory time (TE), inspiratory volume (VI), and minute ventilation (Vm) from 11 normal subjects during stage 2 sleep. The analysis consisted of 1) fitting first- and second-order autoregressive models (AR1 and AR2) and 2) obtaining the power spectra of the data by fast-Fourier transform. For the AR2 model, the only coefficients that were statistically different from zero were the average alpha 1 (a1) for TI, VI, and Vm (a1 = 0.19, 0.29, and 0.15, respectively). However, the power spectra of all parameters often exhibited peaks at low frequency (less than 0.2 cycles/breath) and/or at high frequency (greater than 0.2 cycles/breath), indicative of periodic oscillations. After accounting for the corrupting effects of added oscillations on the a1 estimates, we conclude that 1) breath-to-breath fluctuations of VI, and to a lesser extent TI and Vm, exhibit a first-order autoregressive structure such that fluctuations of each breath are positively correlated with those of immediately preceding breaths and 2) the correlated components of variability in TE are mostly due to discrete high- and/or low-frequency oscillations with no underlying autoregressive structure. We propose that the autoregressive structure of VI, TI, and Vm during spontaneous breathing in stage 2 sleep may reflect either a central neural mechanism or the effects of noise in respiratory chemical feedback loops; the presence of low-frequency oscillations, seen more often in Vm, suggests possible instability in the chemical feedback loops. Mechanisms of high-frequency periodicities, seen more often in TE, are unknown.

  4. Field transients of coherent terahertz synchrotron radiation accessed via time-resolving and correlation techniques

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pohl, A.; Hübers, H.-W.; Institute of Optical Sensor Systems, German Aerospace Center

    2016-03-21

    Decaying oscillations of the electric field in repetitive pulses of coherent synchrotron radiation in the terahertz frequency range was evaluated by means of time-resolving and correlation techniques. Comparative analysis of real-time voltage transients of the electrical response and interferograms, which were obtained with an ultrafast zero-bias Schottky diode detector and a Martin-Puplett interferometer, delivers close values of the pulse duration. Consistent results were obtained via the correlation technique with a pair of Golay Cell detectors and a pair of resonant polarisation-sensitive superconducting detectors integrated on one chip. The duration of terahertz synchrotron pulses does not closely correlate with the durationmore » of single-cycle electric field expected for the varying size of electron bunches. We largely attribute the difference to the charge density oscillations in electron bunches and to the low-frequency spectral cut-off imposed by both the synchrotron beamline and the coupling optics of our detectors.« less

  5. The Role of Oscillatory Phase in Determining the Temporal Organization of Perception: Evidence from Sensory Entrainment.

    PubMed

    Ronconi, Luca; Melcher, David

    2017-11-01

    Recent behavioral, neuroimaging, and neurophysiological studies have renewed the idea that the information processing within different temporal windows is linked to the phase and/or frequency of the ongoing oscillations, predominantly in the theta/alpha band (∼4-7 and 8-12 Hz, respectively). However, being correlational in nature, this evidence might reflect a nonfunctional byproduct rather than having a causal role. A more direct link can be shown with methods that manipulate oscillatory activity. Here, we used audiovisual entrainment at different frequencies in the prestimulus period of a temporal integration/segregation task. We hypothesized that entrainment would align ongoing oscillations and drive them toward the stimulation frequency. To reveal behavioral oscillations in temporal perception after the entrainment, we sampled the segregation/integration performance densely in time. In Experiment 1, two groups of human participants (both males and females) received stimulation either at the lower or the upper boundary of the alpha band (∼8.5 vs 11.5 Hz). For both entrainment frequencies, we found a phase alignment of the perceptual oscillation across subjects, but with two different power spectra that peaked near the entrainment frequency. These results were confirmed when perceptual oscillations were characterized in the time domain with sinusoidal fittings. In Experiment 2, we replicated the findings in a within-subject design, extending the results for frequencies in the theta (∼6.5 Hz), but not in the beta (∼15 Hz), range. Overall, these findings show that temporal segregation can be modified by sensory entrainment, providing evidence for a critical role of ongoing oscillations in the temporal organization of perception. SIGNIFICANCE STATEMENT The continuous flow of sensory input is not processed in an analog fashion, but rather is grouped by the perceptual system over time. Recent studies pinpointed the phase and/or frequency of the neural oscillations in the theta/alpha band (∼4-12 Hz) as possible mechanisms underlying temporal windows in perception. Here, we combined two innovative methodologies to provide more direct support for this evidence. We used sensory entrainment to align neural oscillations to different frequencies and then characterized the resultant perceptual oscillation with a temporal dense sampling of the integration/segregation performance. Our results provide the first evidence that the frequency of temporal segregation can be modified by sensory entrainment, supporting a critical role of ongoing oscillations in the integration/segregation of information over time. Copyright © 2017 Ronconi and Melcher.

  6. UNUSUAL TRENDS IN SOLAR P-MODE FREQUENCIES DURING THE CURRENT EXTENDED MINIMUM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tripathy, S. C.; Jain, K.; Hill, F.

    2010-03-10

    We investigate the behavior of the intermediate-degree mode frequencies of the Sun during the current extended minimum phase to explore the time-varying conditions in the solar interior. Using contemporaneous helioseismic data from the Global Oscillation Network Group (GONG) and the Michelson Doppler Imager (MDI), we find that the changes in resonant mode frequencies during the activity minimum period are significantly greater than the changes in solar activity as measured by different proxies. We detect a seismic minimum in MDI p-mode frequency shifts during 2008 July-August but no such signature is seen in mean shifts computed from GONG frequencies. We alsomore » analyze the frequencies of individual oscillation modes from GONG data as a function of latitude and observe a signature of the onset of the solar cycle 24 in early 2009. Thus, the intermediate-degree modes do not confirm the onset of the cycle 24 during late 2007 as reported from the analysis of the low-degree Global Oscillations at Low Frequency frequencies. Further, both the GONG and MDI frequencies show a surprising anti-correlation between frequencies and activity proxies during the current minimum, in contrast to the behavior during the minimum between cycles 22 and 23.« less

  7. Comprehensive Analysis of RXTE Data from Cyg X-1. Spectral Index-Quasi-Periodic Oscillation Frequency-Luminosity Correlations

    NASA Technical Reports Server (NTRS)

    Shaposhnikov, Nickolai; Titarchuk, Lev

    2006-01-01

    We present timing and spectral analysis of approx. 2.2 Ms of Rossi X-ray Time Explorer (RXTE) archival data from Cyg X-1. Using the generic Comptonization model we reveal that the spectrum of Cyg X-1 consists of three components: a thermal seed photon spectrum, a Comptonized part of the seed photon spectrum and the iron line. We find a strong correlation between 0.1-20 Hz frequencies of quasiperiodic oscillations (QPOs) and the spectral power-law index. Presence of two spectral phases (states) are clearly seen in the data when the spectral indices saturate at low and high values of QPO frequencies. This saturation effect was discovered earlier in a number of black hole candidate (BHC) sources and now we strongly confirm this phenomenon in Cyg X-1. In the soft state this index- QPO frequency correlation shows a saturation of the photon index Gamma approx. 2.1 at high values of the low frequency upsilon(sub L). The saturation level of Gamma approx. 2.1 is the lowest value found yet in BHCs. The bolometric luminosity does not show clear correlation with the index. We also show that Fe K(sub alpha) emission line strength (equivalent width, EW) correlates with the QPO frequency. EW increases from 200 eV in the low/hard state to 1.5 keV in the high/soft state. The revealed observational correlations allow us to propose a scenario for the spectral transition and iron line formation which occur in BHC sources. We also present the spectral state (the power-law index) evolution for eight years of Cyg X-1 observations by RXTE.

  8. Different Stimulation Frequencies Alter Synchronous Fluctuations in Motor Evoked Potential Amplitude of Intrinsic Hand Muscles—a TMS Study

    PubMed Central

    Sale, Martin V.; Rogasch, Nigel C.; Nordstrom, Michael A.

    2016-01-01

    The amplitude of motor-evoked potentials (MEPs) elicited with transcranial magnetic stimulation (TMS) varies from trial-to-trial. Synchronous oscillations in cortical neuronal excitability contribute to this variability, however it is not known how different frequencies of stimulation influence MEP variability, and whether these oscillations are rhythmic or aperiodic. We stimulated the motor cortex with TMS at different regular (i.e., rhythmic) rates, and compared this with pseudo-random (aperiodic) timing. In 18 subjects, TMS was applied at three regular frequencies (0.05 Hz, 0.2 Hz, 1 Hz) and one aperiodic frequency (mean 0.2 Hz). MEPs (n = 50) were recorded from three intrinsic hand muscles of the left hand with different functional and anatomical relations. MEP amplitude correlation was highest for the functionally related muscle pair, less for the anatomically related muscle pair and least for the functionally- and anatomically-unrelated muscle pair. MEP correlations were greatest with 1 Hz, and least for stimulation at 0.05 Hz. Corticospinal neuron synchrony is higher with shorter TMS intervals. Further, corticospinal neuron synchrony is similar irrespective of whether the stimulation is periodic or aperiodic. These findings suggest TMS frequency is a crucial consideration for studies using TMS to probe correlated activity between muscle pairs. PMID:27014031

  9. Characteristics of solar-like oscillations in red giants observed in the CoRoT exoplanet field

    NASA Astrophysics Data System (ADS)

    Hekker, S.; Kallinger, T.; Baudin, F.; De Ridder, J.; Barban, C.; Carrier, F.; Hatzes, A. P.; Weiss, W. W.; Baglin, A.

    2009-10-01

    Context: Observations during the first long run (~150 days) in the exo-planet field of CoRoT increase the number of G-K giant stars for which solar-like oscillations are observed by a factor of 100. This opens the possibility to study the characteristics of their oscillations in a statistical sense. Aims: We aim to understand the statistical distribution of the frequencies of maximum oscillation power (ν_max) in red giants and to search for a possible correlation between ν_max and the large separation (Δ ν). Methods: Red giants with detectable solar-like oscillations are identified using both semi-automatic and manual procedures. For these stars, we determine ν_max as the centre of a Gaussian fit to the oscillation power excess. For the determination of Δ ν, we use the autocorrelation of the Fourier spectra, the comb response function and the power spectrum of the power spectrum. Results: The resulting ν_max distribution shows a pronounced peak between 20-40 μHz. For about half of the stars we obtain Δ ν with at least two methods. The correlation between ν_max and Δ ν follows the same scaling relation as inferred for solar-like stars. Conclusions: The shape of the ν_max distribution can partly be explained by granulation at low frequencies and by white noise at high frequencies, but the population density of the observed stars turns out to be also an important factor. From the fact that the correlation between Δ ν and ν_max for red giants follows the same scaling relation as obtained for sun-like stars, we conclude that the sound travel time over the pressure scale height of the atmosphere scales with the sound travel time through the whole star irrespective of evolution. The fraction of stars for which we determine Δ ν does not correlate with ν_max in the investigated frequency range, which confirms theoretical predictions. The CoRoT space mission which was developed and is operated by the French space agency CNES, with participation of ESA's RSSD and Science Programmes, Austria, Belgium, Brazil, Germany, and Spain. Light curves can be retrieved from the CoRoT archive: http://idoc-corot.ias.u-psud.fr Table 1 is only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A/506/465

  10. Full-Field Measurements of Self-Excited Oscillations in Momentum-Dominated Helium Jets

    NASA Technical Reports Server (NTRS)

    Yildirim, B. S.; Agrawal, A. K.

    2005-01-01

    Flow structure of momentum-dominated helium jets discharged vertically into ambient air was investigated using a high-speed rainbow schlieren deflectometry (RSD) apparatus operated at up to 2000 Hz. The operating parameters, i.e., Reynolds number and Richardson number were varied independently to examine the self-excited, flow oscillatory behavior over a range of experimental conditions. Measurements revealed highly periodic oscillations in the laminar region at a unique frequency as well as high regularity in the flow transition and initial turbulent regions. The buoyancy was shown to affect the oscillation frequency and the distance from the jet exit to the flow transition plane. Instantaneous helium concentration contours across the field of view revealed changes in the jet flow structure and the evolution of the vortical structures during an oscillation cycle. A cross-correlation technique was applied to track the vortices and to find their convection velocity. Time-traces of helium concentration at different axial locations provided detailed information about the oscillating flow.

  11. Functional connectivity changes in adults with developmental stuttering: a preliminary study using quantitative electro-encephalography

    PubMed Central

    Joos, Kathleen; De Ridder, Dirk; Boey, Ronny A.; Vanneste, Sven

    2014-01-01

    Introduction: Stuttering is defined as speech characterized by verbal dysfluencies, but should not be seen as an isolated speech disorder, but as a generalized sensorimotor timing deficit due to impaired communication between speech related brain areas. Therefore we focused on resting state brain activity and functional connectivity. Method: We included 11 patients with developmental stuttering and 11 age matched controls. To objectify stuttering severity and the impact on quality of life (QoL), we used the Dutch validated Test for Stuttering Severity-Readers (TSS-R) and the Overall Assessment of the Speaker’s Experience of Stuttering (OASES), respectively. Furthermore, we used standardized low resolution brain electromagnetic tomography (sLORETA) analyses to look at resting state activity and functional connectivity differences and their correlations with the TSS-R and OASES. Results: No significant results could be obtained when looking at neural activity, however significant alterations in resting state functional connectivity could be demonstrated between persons who stutter (PWS) and fluently speaking controls, predominantly interhemispheric, i.e., a decreased functional connectivity for high frequency oscillations (beta and gamma) between motor speech areas (BA44 and 45) and the contralateral premotor (BA6) and motor (BA4) areas. Moreover, a positive correlation was found between functional connectivity at low frequency oscillations (theta and alpha) and stuttering severity, while a mixed increased and decreased functional connectivity at low and high frequency oscillations correlated with QoL. Discussion: PWS are characterized by decreased high frequency interhemispheric functional connectivity between motor speech, premotor and motor areas in the resting state, while higher functional connectivity in the low frequency bands indicates more severe speech disturbances, suggesting that increased interhemispheric and right sided functional connectivity is maladaptive. PMID:25352797

  12. Slow oscillation of membrane currents mediated by glutamatergic inputs of rat somatosensory cortical neurons: in vivo patch-clamp analysis.

    PubMed

    Doi, Atsushi; Mizuno, Masaharu; Katafuchi, Toshihiko; Furue, Hidemasa; Koga, Kohei; Yoshimura, Megumu

    2007-11-01

    Using in vivo patch-clamp technique, the slow oscillation of membrane currents was characterized by its synaptic nature, correlation with electroencephalogram (EEG) and responses to different anesthetic agents, in primary somatosensory cortex (SI) neurons in urethane-anesthetized rats. In more than 90% of the SI neurons, the slow oscillation of the inward currents (0.1-2.5 Hz) with the duration of several hundreds of a millisecond was observed at the holding membrane potential of -70 mV. The reversal potential of the inward currents was approximately 0 mV and was suppressed by application of an alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor antagonist. In most cases (> 90%) the inward current was synchronized with positive wave of the surface EEG recorded from ipsilateral and even contralateral cortical regions. The frequency as well as duration of the slow oscillation decreased by a volatile anesthetic agent, isoflurane (1.5-5.0%), and excitatory postsynaptic currents (EPSCs) were almost abolished at the highest concentration. Intraperitoneal injection of pentobarbital (25 mg/kg) also decreased the frequency of the slow oscillation without affecting short EPSCs. When gamma-aminobutyric acid A (GABA(A)) receptors were activated by local microinjection of muscimol (3 x 10(-3) m, 1-10 microL) into the thalamus, the frequency of the slow oscillation markedly decreased, but was not abolished completely. These findings suggest that the slow oscillation of the inward currents is generated by the summation of glutamatergic EPSCs, and affected by isoflurane and pentobarbital differently. In addition, GABAergic system in the thalamus can affect the frequency, but is not essentially implicated in the genesis of the slow oscillation.

  13. Experimental study of the oscillating flow characteristics for a regenerator in a pulse tube cryocooler

    NASA Astrophysics Data System (ADS)

    Ju, Yonglin; Jiang, Yan; Zhou, Yuan

    A dynamic experimental apparatus was designed and constructed to investigate oscillating flow characteristics in a regenerator subjected to a periodically reversing flow established by means of a self-made linear compressor. Detailed experimental data of oscillating pressure drops and phase shift characteristics for regenerators in a high frequency pulse tube cryocooler with an operating frequency of 50 Hz were given. The correlation equations for the maximum and cycle-averaged friction factors in terms of Reynolds numbers and dimensionless distance X were obtained. It was found that the value of the cycle-averaged pressure drop in the oscillating flow across the regenerator is two to three times higher than that of a steady flow at the same Reynolds numbers based on the cross-sectional mean velocity. In addition, the relationship of the phase shifts between the velocity and pressure wave is also discussed.

  14. Calculations of wall shear stress in harmonically oscillated turbulent pipe flow using a low-Reynolds-number {kappa}-{epsilon} model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ismael, J.O.; Cotton, M.A.

    1996-03-01

    The low-Reynolds-number {kappa}-{epsilon} turbulence model of Launder and Sharma is applied to the calculation of wall shear stress in spatially fully-developed turbulent pipe flow oscillated at small amplitudes. It is believed that the present study represents the first systematic evaluation of the turbulence closure under consideration over a wide range of frequency. Model results are well correlated in terms of the parameter {omega}{sup +} = {omega}{nu}/{bar U}{sub {tau}}{sup 2} at high frequencies, whereas at low frequencies there is an additional Reynolds number dependence. Comparison is made with the experimental data of Finnicum and Hanratty.

  15. On one-parametric formula relating the frequencies of twin-peak quasi-periodic oscillations

    NASA Astrophysics Data System (ADS)

    Török, Gabriel; Goluchová, Kateřina; Šrámková, Eva; Horák, Jiří; Bakala, Pavel; Urbanec, Martin

    2018-01-01

    Twin-peak quasi-periodic oscillations (QPOs) are observed in several low-mass X-ray binary systems containing neutron stars. Timing the analysis of X-ray fluxes of more than dozen of such systems reveals remarkable correlations between the frequencies of two characteristic peaks present in the power density spectra. The individual correlations clearly differ, but they roughly follow a common individual pattern. High values of measured QPO frequencies and strong modulation of the X-ray flux both suggest that the observed correlations are connected to orbital motion in the innermost part of an accretion disc. Several attempts to model these correlations with simple geodesic orbital models or phenomenological relations have failed in the past. We find and explore a surprisingly simple analytic relation that reproduces individual correlations for a group of several sources through a single parameter. When an additional free parameter is considered within our relation, it well reproduces the data of a large group of 14 sources. The very existence and form of this simple relation support the hypothesis of the orbital origin of QPOs and provide the key for further development of QPO models. We discuss a possible physical interpretation of our relation's parameters and their links to concrete QPO models.

  16. The measurement of linear frequency drift in oscillators

    NASA Astrophysics Data System (ADS)

    Barnes, J. A.

    1985-04-01

    A linear drift in frequency is an important element in most stochastic models of oscillator performance. Quartz crystal oscillators often have drifts in excess of a part in ten to the tenth power per day. Even commercial cesium beam devices often show drifts of a few parts in ten to the thirteenth per year. There are many ways to estimate the drift rates from data samples (e.g., regress the phase on a quadratic; regress the frequency on a linear; compute the simple mean of the first difference of frequency; use Kalman filters with a drift term as one element in the state vector; and others). Although most of these estimators are unbiased, they vary in efficiency (i.e., confidence intervals). Further, the estimation of confidence intervals using the standard analysis of variance (typically associated with the specific estimating technique) can give amazingly optimistic results. The source of these problems is not an error in, say, the regressions techniques, but rather the problems arise from correlations within the residuals. That is, the oscillator model is often not consistent with constraints on the analysis technique or, in other words, some specific analysis techniques are often inappropriate for the task at hand. The appropriateness of a specific analysis technique is critically dependent on the oscillator model and can often be checked with a simple whiteness test on the residuals.

  17. Current-driven ion-acoustic and potential-relaxation instabilities excited in plasma plume during electron beam welding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Trushnikov, D. N., E-mail: trdimitr@yandex.ru; Mladenov, G. M., E-mail: gmmladenov@abv.bg; Koleva, E. G., E-mail: eligeorg@abv.bg

    Many papers have sought correlations between the parameters of secondary particles generated above the beam/work piece interaction zone, dynamics of processes in the keyhole, and technological processes. Low- and high-frequency oscillations of the current, collected by plasma have been observed above the welding zone during electron beam welding. Low-frequency oscillations of secondary signals are related to capillary instabilities of the keyhole, however; the physical mechanisms responsible for the high-frequency oscillations (>10 kHz) of the collected current are not fully understood. This paper shows that peak frequencies in the spectra of the collected high-frequency signal are dependent on the reciprocal distancemore » between the welding zone and collector electrode. From the relationship between current harmonics frequency and distance of the collector/welding zone, it can be estimated that the draft velocity of electrons or phase velocity of excited waves is about 1600 m/s. The dispersion relation with the properties of ion-acoustic waves is related to electron temperature 10 000 K, ion temperature 2 400 K and plasma density 10{sup 16} m{sup −3}, which is analogues to the parameters of potential-relaxation instabilities, observed in similar conditions. The estimated critical density of the transported current for creating the anomalous resistance state of plasma is of the order of 3 A·m{sup −2}, i.e. 8 mA for a 3–10 cm{sup 2} collector electrode. Thus, it is assumed that the observed high-frequency oscillations of the current collected by the positive collector electrode are caused by relaxation processes in the plasma plume above the welding zone, and not a direct demonstration of oscillations in the keyhole.« less

  18. Current-driven ion-acoustic and potential-relaxation instabilities excited in plasma plume during electron beam welding

    NASA Astrophysics Data System (ADS)

    Trushnikov, D. N.; Mladenov, G. M.; Belenkiy, V. Ya.; Koleva, E. G.; Varushkin, S. V.

    2014-04-01

    Many papers have sought correlations between the parameters of secondary particles generated above the beam/work piece interaction zone, dynamics of processes in the keyhole, and technological processes. Low- and high-frequency oscillations of the current, collected by plasma have been observed above the welding zone during electron beam welding. Low-frequency oscillations of secondary signals are related to capillary instabilities of the keyhole, however; the physical mechanisms responsible for the high-frequency oscillations (>10 kHz) of the collected current are not fully understood. This paper shows that peak frequencies in the spectra of the collected high-frequency signal are dependent on the reciprocal distance between the welding zone and collector electrode. From the relationship between current harmonics frequency and distance of the collector/welding zone, it can be estimated that the draft velocity of electrons or phase velocity of excited waves is about 1600 m/s. The dispersion relation with the properties of ion-acoustic waves is related to electron temperature 10 000 K, ion temperature 2 400 K and plasma density 1016 m-3, which is analogues to the parameters of potential-relaxation instabilities, observed in similar conditions. The estimated critical density of the transported current for creating the anomalous resistance state of plasma is of the order of 3 A.m-2, i.e. 8 mA for a 3-10 cm2 collector electrode. Thus, it is assumed that the observed high-frequency oscillations of the current collected by the positive collector electrode are caused by relaxation processes in the plasma plume above the welding zone, and not a direct demonstration of oscillations in the keyhole.

  19. Quantitative EEG and low resolution electromagnetic tomography (LORETA) imaging of patients with persistent auditory hallucinations.

    PubMed

    Lee, Seung-Hwan; Wynn, Jonathan K; Green, Michael F; Kim, Hyun; Lee, Kang-Joon; Nam, Min; Park, Joong-Kyu; Chung, Young-Cho

    2006-04-01

    Electrophysiological studies have demonstrated gamma and beta frequency oscillations in response to auditory stimuli. The purpose of this study was to test whether auditory hallucinations (AH) in schizophrenia patients reflect abnormalities in gamma and beta frequency oscillations and to investigate source generators of these abnormalities. This theory was tested using quantitative electroencephalography (qEEG) and low-resolution electromagnetic tomography (LORETA) source imaging. Twenty-five schizophrenia patients with treatment refractory AH, lasting for at least 2 years, and 23 schizophrenia patients with non-AH (N-AH) in the past 2 years were recruited for the study. Spectral analysis of the qEEG and source imaging of frequency bands of artifact-free 30 s epochs were examined during rest. AH patients showed significantly increased beta 1 and beta 2 frequency amplitude compared with N-AH patients. Gamma and beta (2 and 3) frequencies were significantly correlated in AH but not in N-AH patients. Source imaging revealed significantly increased beta (1 and 2) activity in the left inferior parietal lobule and the left medial frontal gyrus in AH versus N-AH patients. These results imply that AH is reflecting increased beta frequency oscillations with neural generators localized in speech-related areas.

  20. Corrective jitter motion shows similar individual frequencies for the arm and the finger.

    PubMed

    Noy, Lior; Alon, Uri; Friedman, Jason

    2015-04-01

    A characteristic of visuomotor tracking of non-regular oscillating stimuli are high-frequency jittery corrective motions, oscillating around the tracked stimuli. However, the properties of these corrective jitter responses are not well understood. For example, does the jitter response show an idiosyncratic signature? What is the relationship between stimuli properties and jitter properties? Is the jitter response similar across effectors with different inertial properties? To answer these questions, we measured participants' jitter frequencies in two tracking tasks in the arm and the finger. Thirty participants tracked the same set of eleven non-regular oscillating stimuli, vertically moving on a screen, once with forward-backward arm movements (holding a tablet stylus) and once with upward-downward index finger movements (with a motion tracker attached). Participants' jitter frequencies and tracking errors varied systematically as a function of stimuli frequency and amplitude. Additionally, there were clear individual differences in average jitter frequencies between participants, ranging from 0.7 to 1.15 Hz, similar to values reported previously. A comparison of individual jitter frequencies in the two tasks showed a strong correlation between participants' jitter frequencies in the finger and the arm, despite the very different inertial properties of the two effectors. This result suggests that the corrective jitter response stems from common neural processes.

  1. Evidence for an Optical Low-frequency Quasi-periodic Oscillation in the Kepler Light Curve of an Active Galaxy

    NASA Astrophysics Data System (ADS)

    Smith, Krista Lynne; Mushotzky, Richard F.; Boyd, Patricia T.; Wagoner, Robert V.

    2018-06-01

    We report evidence for a quasi-periodic oscillation (QPO) in the optical light curve of KIC 9650712, a narrow-line Seyfert 1 galaxy in the original Kepler field. After the development and application of a pipeline for Kepler data specific to active galactic nuclei (AGNs), one of our sample of 21 AGNs selected by infrared photometry and X-ray flux demonstrates a peak in the power spectrum at log ν = ‑6.58 Hz, corresponding to a temporal period of t = 44 days. We note that although the power spectrum is well fit by a model consisting of a Lorentzian and a single power law, alternative continuum models cannot be ruled out. From optical spectroscopy, we measure the black hole mass of this AGN as log (M BH/M ⊙) = 8.17. We find that this frequency lies along a correlation between low-frequency QPOs and black hole mass from stellar and intermediate mass black holes to AGNs, similar to the known correlation in high-frequency QPOs.

  2. Relationship between neighbor number and vibrational spectra in disordered colloidal clusters with attractive interactions

    NASA Astrophysics Data System (ADS)

    Yunker, Peter J.; Zhang, Zexin; Gratale, Matthew; Chen, Ke; Yodh, A. G.

    2013-03-01

    We study connections between vibrational spectra and average nearest neighbor number in disordered clusters of colloidal particles with attractive interactions. Measurements of displacement covariances between particles in each cluster permit calculation of the stiffness matrix, which contains effective spring constants linking pairs of particles. From the cluster stiffness matrix, we derive vibrational properties of corresponding "shadow" glassy clusters, with the same geometric configuration and interactions as the "source" cluster but without damping. Here, we investigate the stiffness matrix to elucidate the origin of the correlations between the median frequency of cluster vibrational modes and average number of nearest neighbors in the cluster. We find that the mean confining stiffness of particles in a cluster, i.e., the ensemble-averaged sum of nearest neighbor spring constants, correlates strongly with average nearest neighbor number, and even more strongly with median frequency. Further, we find that the average oscillation frequency of an individual particle is set by the total stiffness of its nearest neighbor bonds; this average frequency increases as the square root of the nearest neighbor bond stiffness, in a manner similar to the simple harmonic oscillator.

  3. Structural and Functional Effect of an Oscillating Electric Field on the Dopamine-D3 Receptor: A Molecular Dynamics Simulation Study

    PubMed Central

    Fallah, Zohreh; Jamali, Yousef; Rafii-Tabar, Hashem

    2016-01-01

    Dopamine as a neurotransmitter plays a critical role in the functioning of the central nervous system. The structure of D3 receptor as a member of class A G-protein coupled receptors (GPCRs) has been reported. We used MD simulation to investigate the effect of an oscillating electric field, with frequencies in the range 0.6–800 GHz applied along the z-direction, on the dopamine-D3R complex. The simulations showed that at some frequencies, the application of an external oscillating electric field along the z-direction has a considerable effect on the dopamine-D3R. However, there is no enough evidence for prediction of changes in specific frequency, implying that there is no order in changes. Computing the correlation coefficient parameter showed that increasing the field frequency can weaken the interaction between dopamine and D3R and may decrease the Arg128{3.50}-Glu324{6.30} distance. Because of high stability of α helices along the z-direction, applying an oscillating electric field in this direction with an amplitude 10-time higher did not have a considerable effect. However, applying the oscillating field at the frequency of 0.6 GHz along other directions, such as X-Y and Y-Z planes, could change the energy between the dopamine and the D3R, and the number of internal hydrogen bonds of the protein. This can be due to the effect of the direction of the electric field vis-à-vis the ligands orientation and the interaction of the oscillating electric field with the dipole moment of the protein. PMID:27832207

  4. Association of specific frequency bands of functional MRI signal oscillations with motor symptoms and depression in Parkinson's disease.

    PubMed

    Song, Xiaopeng; Hu, Xiao; Zhou, Shuqin; Xu, Yuanyuan; Zhang, Yi; Yuan, Yonggui; Liu, Yijun; Zhu, Huaiqiu; Liu, Weiguo; Gao, Jia-Hong

    2015-11-17

    A novel empirical mode decomposition method was adopted to investigate the dissociative or interactive neural impact of depression and motor impairments in Parkinson's disease (PD). Resting-state fMRI data of 59 PD subjects were first decomposed into characteristic frequency bands, and the main effects of motor severity and depression and their interaction on the energy of blood-oxygen-level-dependent signal oscillation in specific frequency bands were then evaluated. The results show that the severity of motor symptoms is negatively correlated with the energy in the frequency band of 0.10-0.25 Hz in the bilateral thalamus, but positively correlated with 0.01-0.027 Hz band energy in the bilateral postcentral gyrus. The severity of depression, on the other hand, is positively correlated with the energy of 0.10-0.25 Hz but negatively with 0.01-0.027 Hz in the bilateral subgenual gyrus. Notably, the interaction between motor and depressive symptoms is negatively correlated with the energy of 0.10-0.25 Hz in the substantia nigra, hippocampus, inferior orbitofrontal cortex, and temporoparietal junction, but positively correlated with 0.02-0.05 Hz in the same regions. These findings indicate unique associations of fMRI band signals with motor and depressive symptoms in PD in specific brain regions, which may underscore the neural impact of the comorbidity and the differentiation between the two PD-related disorders.

  5. Detailed Characterization of Local Field Potential Oscillations and Their Relationship to Spike Timing in the Antennal Lobe of the Moth Manduca sexta

    PubMed Central

    Daly, Kevin C.; Galán, Roberto F.; Peters, Oakland J.; Staudacher, Erich M.

    2011-01-01

    The transient oscillatory model of odor identity encoding seeks to explain how odorants with spatially overlapped patterns of input into primary olfactory networks can be discriminated. This model provides several testable predictions about the distributed nature of network oscillations and how they control spike timing. To test these predictions, 16 channel electrode arrays were placed within the antennal lobe (AL) of the moth Manduca sexta. Unitary spiking and multi site local field potential (LFP) recordings were made during spontaneous activity and in response to repeated presentations of an odor panel. We quantified oscillatory frequency, cross correlations between LFP recording sites, and spike–LFP phase relationships. We show that odor-driven AL oscillations in Manduca are frequency modulating (FM) from ∼100 to 30 Hz; this was odorant and stimulus duration dependent. FM oscillatory responses were localized to one or two recording sites suggesting a localized (perhaps glomerular) not distributed source. LFP cross correlations further demonstrated that only a small (r < 0.05) distributed and oscillatory component was present. Cross spectral density analysis demonstrated the frequency of these weakly distributed oscillations was state dependent (spontaneous activity = 25–55 Hz; odor-driven = 55–85 Hz). Surprisingly, vector strength analysis indicated that unitary phase locking of spikes to the LFP was strongest during spontaneous activity and dropped significantly during responses. Application of bicuculline, a GABAA receptor antagonist, significantly lowered the frequency content of odor-driven distributed oscillatory activity. Bicuculline significantly reduced spike phase locking generally, but the ubiquitous pattern of increased phase locking during spontaneous activity persisted. Collectively, these results indicate that oscillations perform poorly as a stimulus-mediated spike synchronizing mechanism for Manduca and hence are incongruent with the transient oscillatory model. PMID:22046161

  6. Experimental and analytical study of thermal acoustic oscillations. [in the transfer and storage of cryogens

    NASA Technical Reports Server (NTRS)

    Spradley, L. W.; Dean, W. G.; Karu, Z. S.

    1976-01-01

    The thermal acoustic oscillations (TAO) data base was expanded by running a large number of tubes over a wide range of parameters known to affect the TAO phenomenon. These parameters include tube length, wall thickness, diameter, material, insertion length and length-to-diameter ratio. Emphasis was placed on getting good boiloff data. A large quantity of data was obtained, reduced, correlated and analyzed and is presented. Also presented are comparisons with previous types of correlations. These comparisons show that the boiloff data did not correlate with intensity. The data did correlate in the form used by Rott, that is boiloff versus TAO pressure squared times frequency to the one-half power. However, this latter correlation required a different set of correlation constants, slope and intercept, for each tube tested.

  7. Endogenously generated gamma-band oscillations in early visual cortex: A neurofeedback study.

    PubMed

    Merkel, Nina; Wibral, Michael; Bland, Gareth; Singer, Wolf

    2018-04-26

    Human subjects were trained with neurofeedback (NFB) to enhance the power of narrow-band gamma oscillations in circumscribed regions of early visual cortex. To select the region and the oscillation frequency for NFB training, gamma oscillations were induced with locally presented drifting gratings. The source and frequency of these induced oscillations were determined using beamforming methods. During NFB training the power of narrow band gamma oscillations was continuously extracted from this source with online beamforming and converted into the pitch of a tone signal. We found that seven out of ten subjects were able to selectively increase the amplitude of gamma oscillations in the absence of visual stimulation. One subject however failed completely and two subjects succeeded to manipulate the feedback signal by contraction of muscles. In all subjects the attempts to enhance visual gamma oscillations were associated with an increase of beta oscillations over precentral/frontal regions. Only successful subjects exhibited an additional marked increase of theta oscillations over precentral/prefrontal and temporal regions whereas unsuccessful subjects showed an increase of alpha band oscillations over occipital regions. We argue that spatially confined networks in early visual cortex can be entrained to engage in narrow band gamma oscillations not only by visual stimuli but also by top down signals. We interpret the concomitant increase in beta oscillations as indication for an engagement of the fronto-parietal attention network and the increase of theta oscillations as a correlate of imagery. Our finding support the application of NFB in disease conditions associated with impaired gamma synchronization. © 2018 Wiley Periodicals, Inc.

  8. A multiscale interaction model for the origin of the tropospheric QBO

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goswami, B.N.

    1995-03-01

    A conceptual model for the origin of the tropospheric quasi-biennial oscillation (QBO) is presented. It is argued that the tropospheric QBO may not be a fundamental mode of oscillation of the tropical coupled system. It is proposed that it may arise due to multiscale interactions between high-frequency synoptic and intraseasonal oscillations of the atmosphere and a low-frequency oscillation of the couple system in the presence of the annual cycle. This is demonstrated using a conceptual low-order system consisting of three variables representing the nonlinear atmospheric oscillations and a linear oscillator representing the low-frequency coupled mode. The annual cycle and couplingmore » to the low-frequency linear oscillator provide slowly varying forcings for the atmospheric high-frequency oscillations. The atmospheric oscillations go through a chaotic regime during a certain part of the slowly varying forcing. Such variable forcing introduces a low-frequency tail in the spectrum of the atmospheric high-frequency oscillations. The low-frequency tail resonantly interacts with the low-frequency oscillation and produces the QBO in addition to broadening the spectrum of the low-frequency oscillator. The conceptual model simulates features similar to many observed features of the tropospheric QBO but depends on the assumption that there is an inherent low-frequency El Nino-Southern Oscillation oscillation with a four-year period that occurs independently of the high-frequency forcing or the QBO.« less

  9. Harmonic Brain Modes: A Unifying Framework for Linking Space and Time in Brain Dynamics.

    PubMed

    Atasoy, Selen; Deco, Gustavo; Kringelbach, Morten L; Pearson, Joel

    2018-06-01

    A fundamental characteristic of spontaneous brain activity is coherent oscillations covering a wide range of frequencies. Interestingly, these temporal oscillations are highly correlated among spatially distributed cortical areas forming structured correlation patterns known as the resting state networks, although the brain is never truly at "rest." Here, we introduce the concept of harmonic brain modes-fundamental building blocks of complex spatiotemporal patterns of neural activity. We define these elementary harmonic brain modes as harmonic modes of structural connectivity; that is, connectome harmonics, yielding fully synchronous neural activity patterns with different frequency oscillations emerging on and constrained by the particular structure of the brain. Hence, this particular definition implicitly links the hitherto poorly understood dimensions of space and time in brain dynamics and its underlying anatomy. Further we show how harmonic brain modes can explain the relationship between neurophysiological, temporal, and network-level changes in the brain across different mental states ( wakefulness, sleep, anesthesia, psychedelic). Notably, when decoded as activation of connectome harmonics, spatial and temporal characteristics of neural activity naturally emerge from the interplay between excitation and inhibition and this critical relation fits the spatial, temporal, and neurophysiological changes associated with different mental states. Thus, the introduced framework of harmonic brain modes not only establishes a relation between the spatial structure of correlation patterns and temporal oscillations (linking space and time in brain dynamics), but also enables a new dimension of tools for understanding fundamental principles underlying brain dynamics in different states of consciousness.

  10. Dynamic Runner Forces and Pressure Fluctuations on the Draft Tube Wall of a Model Pump-Turbine

    NASA Astrophysics Data System (ADS)

    Kirschner, O.; Ruprecht, A.; Göde, E.; Riedelbauch, S.

    2016-11-01

    When Francis-turbines and pump-turbines operate at off-design conditions, typically a vortex rope develops. The vortex rope causes pressure oscillations leading to fluctuations of the forces affecting the runner. The presence of dynamic runner forces over a long period of time might damage the bearings and possibly the runner. In this experimental investigation, the fluctuating part of the runner forces and the pressure oscillations on the draft tube wall were measured on a model pump-turbine with a simplified straight cone draft tube in different operating conditions. The investigation focuses on the correlation of the pressure fluctuations frequency measured at the draft tube wall with the frequency of the fluctuating forces on the runner. The comparison between pressure fluctuations and dynamic forces shows a significant correlation in all operating points. For the comparison of different components in the spatial directions of the forces, the pressure fluctuations were separated in a synchronous part and a rotating part for operating points with higher amplitudes. The rotating pressure fluctuations correlate with the radial forces especially in the operating points with a rotating vortex rope. At frequencies with higher amplitudes in the pressure fluctuations caused by the vortex rope movement, there are also higher amplitudes in the radial forces at the same frequencies.

  11. Heart rate and respiratory rhythm dynamics on ascent to high altitude.

    PubMed Central

    Lipsitz, L. A.; Hashimoto, F.; Lubowsky, L. P.; Mietus, J.; Moody, G. B.; Appenzeller, O.; Goldberger, A. L.

    1995-01-01

    OBJECTIVE--To investigate the alterations in autonomic control of heart rate at high altitude and to test the hypothesis that hypoxaemic stress during exposure to high altitude induces non-linear, periodic heart rate oscillations, similar to those seen in heart failure and the sleep apnoea syndrome. SUBJECTS--11 healthy subjects aged 24-64. MAIN OUTCOME MEASURES--24 hour ambulatory electrocardiogram records obtained at baseline (1524 m) and at 4700 m. Simultaneous heart rate and respiratory dynamics during 2.5 hours of sleep by fast Fourier transform analysis of beat to beat heart rate and of an electrocardiographically derived respiration signal. RESULTS--All subjects had resting hypoxaemia at high altitude, with an average oxyhaemoglobin saturation of 81% (5%). There was no significant change in mean heart rate, but low frequency (0.01-0.05 Hz) spectral power was increased (P < 0.01) at high altitude. Time series analysis showed a complex range of non-linear sinus rhythm dynamics. Striking low frequency (0.04-0.06 Hz) heart rate oscillations were observed during sleep in eight subjects at high altitude. Analysis of the electrocardiographically derived respiration signal indicated that these heart rate oscillations correlated with low frequency respiratory oscillations. CONCLUSIONS--These data suggest (a) that increased low frequency power during high altitude exposure is not simply attributable to increased sympathetic modulation of heart rate, but relates to distinctive cardiopulmonary oscillations at approximately 0.05 Hz and (b) that the emergence of periodic heart rate oscillations at high altitude is consistent with an unstable cardiopulmonary control system that may develop on acute exposure to hypoxaemic stress. PMID:7488453

  12. Heart rate and respiratory rhythm dynamics on ascent to high altitude

    NASA Technical Reports Server (NTRS)

    Lipsitz, L. A.; Hashimoto, F.; Lubowsky, L. P.; Mietus, J.; Moody, G. B.; Appenzeller, O.; Goldberger, A. L.

    1995-01-01

    OBJECTIVE--To investigate the alterations in autonomic control of heart rate at high altitude and to test the hypothesis that hypoxaemic stress during exposure to high altitude induces non-linear, periodic heart rate oscillations, similar to those seen in heart failure and the sleep apnoea syndrome. SUBJECTS--11 healthy subjects aged 24-64. MAIN OUTCOME MEASURES--24 hour ambulatory electrocardiogram records obtained at baseline (1524 m) and at 4700 m. Simultaneous heart rate and respiratory dynamics during 2.5 hours of sleep by fast Fourier transform analysis of beat to beat heart rate and of an electrocardiographically derived respiration signal. RESULTS--All subjects had resting hypoxaemia at high altitude, with an average oxyhaemoglobin saturation of 81% (5%). There was no significant change in mean heart rate, but low frequency (0.01-0.05 Hz) spectral power was increased (P < 0.01) at high altitude. Time series analysis showed a complex range of non-linear sinus rhythm dynamics. Striking low frequency (0.04-0.06 Hz) heart rate oscillations were observed during sleep in eight subjects at high altitude. Analysis of the electrocardiographically derived respiration signal indicated that these heart rate oscillations correlated with low frequency respiratory oscillations. CONCLUSIONS--These data suggest (a) that increased low frequency power during high altitude exposure is not simply attributable to increased sympathetic modulation of heart rate, but relates to distinctive cardiopulmonary oscillations at approximately 0.05 Hz and (b) that the emergence of periodic heart rate oscillations at high altitude is consistent with an unstable cardiopulmonary control system that may develop on acute exposure to hypoxaemic stress.

  13. Induction of θ-frequency oscillations in the rat medial septal diagonal band slice by metabotropic glutamate receptor agonists.

    PubMed

    Lu, C B; Ouyang, G; Henderson, Z; Li, X

    2011-03-17

    The aim of this study was to examine the role of metabotropic glutamate receptors (mGluR) in the generation of oscillatory field activity at theta frequency (4-12 Hz) in the medial septal slice prepared from rat brain. Bath application of mGluR agonists and antagonists showed that activation of mGluR1-type receptors produces persistent theta frequency oscillations in a dose-responsive manner. This activity, induced by the group I mGluR agonist (RS)-3,5-dihydroxyphenylglycine (DHPG), was reduced by ionotropic glutamate receptor antagonists and abolished by further addition of a GABAA receptor antagonist. However, addition of a GABAA receptor antagonist on its own converted the DHPG-induced oscillations to intermittent episodes of accentuated theta frequency activity following a burst. In a proportion of slices, DHPG induced large amplitude field population spiking activity (100-300 μV) which is correlated linearly with the field theta oscillations and is sensitive to glutamate receptor antagonists, suggesting a role of this type of spikes in theta generation induced by DHPG. These data demonstrate that DHPG-sensitive neuronal networks within medial septum generate theta rhythmic activity and are differentially modulated by excitatory and inhibitory ionotropic neurotransmissions. Copyright © 2011 IBRO. Published by Elsevier Ltd. All rights reserved.

  14. A Linear Model of Phase-Dependent Power Correlations in Neuronal Oscillations

    PubMed Central

    Eriksson, David; Vicente, Raul; Schmidt, Kerstin

    2011-01-01

    Recently, it has been suggested that effective interactions between two neuronal populations are supported by the phase difference between the oscillations in these two populations, a hypothesis referred to as “communication through coherence” (CTC). Experimental work quantified effective interactions by means of the power correlations between the two populations, where power was calculated on the local field potential and/or multi-unit activity. Here, we present a linear model of interacting oscillators that accounts for the phase dependency of the power correlation between the two populations and that can be used as a reference for detecting non-linearities such as gain control. In the experimental analysis, trials were sorted according to the coupled phase difference of the oscillators while the putative interaction between oscillations was taking place. Taking advantage of the modeling, we further studied the dependency of the power correlation on the uncoupled phase difference, connection strength, and topology. Since the uncoupled phase difference, i.e., the phase relation before the effective interaction, is the causal variable in the CTC hypothesis we also describe how power correlations depend on that variable. For uni-directional connectivity we observe that the width of the uncoupled phase dependency is broader than for the coupled phase. Furthermore, the analytical results show that the characteristics of the phase dependency change when a bidirectional connection is assumed. The width of the phase dependency indicates which oscillation frequencies are optimal for a given connection delay distribution. We propose that a certain width enables a stimulus-contrast dependent extent of effective long-range lateral connections. PMID:21808618

  15. Effective deep brain stimulation suppresses low-frequency network oscillations in the basal ganglia by regularizing neural firing patterns.

    PubMed

    McConnell, George C; So, Rosa Q; Hilliard, Justin D; Lopomo, Paola; Grill, Warren M

    2012-11-07

    Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for the motor symptoms of Parkinson's disease (PD). The effects of DBS depend strongly on stimulation frequency: high frequencies (>90 Hz) improve motor symptoms, while low frequencies (<50 Hz) are either ineffective or exacerbate symptoms. The neuronal basis for these frequency-dependent effects of DBS is unclear. The effects of different frequencies of STN-DBS on behavior and single-unit neuronal activity in the basal ganglia were studied in the unilateral 6-hydroxydopamine lesioned rat model of PD. Only high-frequency DBS reversed motor symptoms, and the effectiveness of DBS depended strongly on stimulation frequency in a manner reminiscent of its clinical effects in persons with PD. Quantification of single-unit activity in the globus pallidus externa (GPe) and substantia nigra reticulata (SNr) revealed that high-frequency DBS, but not low-frequency DBS, reduced pathological low-frequency oscillations (∼9 Hz) and entrained neurons to fire at the stimulation frequency. Similarly, the coherence between simultaneously recorded pairs of neurons within and across GPe and SNr shifted from the pathological low-frequency band to the stimulation frequency during high-frequency DBS, but not during low-frequency DBS. The changes in firing patterns in basal ganglia neurons were not correlated with changes in firing rate. These results indicate that high-frequency DBS is more effective than low-frequency DBS, not as a result of changes in firing rate, but rather due to its ability to replace pathological low-frequency network oscillations with a regularized pattern of neuronal firing.

  16. Effective deep brain stimulation suppresses low frequency network oscillations in the basal ganglia by regularizing neural firing patterns

    PubMed Central

    McConnell, George C.; So, Rosa Q.; Hilliard, Justin D; Lopomo, Paola; Grill, Warren M.

    2012-01-01

    Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for the motor symptoms of Parkinson’s disease (PD). The effects of DBS depend strongly on stimulation frequency: high frequencies (>90Hz) improve motor symptoms, while low frequencies (<50Hz) are either ineffective or exacerbate symptoms. The neuronal basis for these frequency-dependent effects of DBS is unclear. The effects of different frequencies of STN-DBS on behavior and single-unit neuronal activity in the basal ganglia were studied in the unilateral 6-hydroxydopamine lesioned rat model of PD. Only high frequency DBS reversed motor symptoms and the effectiveness of DBS depended strongly on stimulation frequency in a manner reminiscent of its clinical effects in persons with PD. Quantification of single-unit activity in the globus pallidus externa (GPe) and substantia nigra reticulata (SNr) revealed that high frequency DBS, but not low frequency DBS, reduced pathological low frequency oscillations (~9Hz) and entrained neurons to fire at the stimulation frequency. Similarly, the coherence between simultaneously recorded pairs of neurons within and across GPe and SNr shifted from the pathological low frequency band to the stimulation frequency during high frequency DBS, but not during low frequency DBS. The changes in firing patterns in basal ganglia neurons were not correlated with changes in firing rate. These results indicate that high frequency DBS is more effective than low frequency DBS, not as a result of changes in firing rate, but rather due to its ability to replace pathological low frequency network oscillations with a regularized pattern of neuronal firing. PMID:23136407

  17. Resting state low-frequency fluctuations in prefrontal cortex reflect degrees of harm avoidance and novelty seeking: an exploratory NIRS study

    PubMed Central

    Nakao, Takashi; Matsumoto, Tomoya; Shimizu, Daisuke; Morita, Machiko; Yoshimura, Shinpei; Northoff, Georg; Morinobu, Shigeru; Okamoto, Yasumasa; Yamawaki, Shigeto

    2013-01-01

    Harm avoidance (HA) and novelty seeking (NS) are temperament dimensions defined by Temperament and Character Inventory (TCI), respectively, reflecting a heritable bias for intense response to aversive stimuli or for excitement in response to novel stimuli. High HA is regarded as a risk factor for major depressive disorder and anxiety disorder. In contrast, higher NS is linked to increased risk for substance abuse and pathological gambling disorder. A growing body of evidence suggests that patients with these disorders show abnormality in the power of slow oscillations of resting-state brain activity. It is particularly interesting that previous studies have demonstrated that resting state activities in medial prefrontal cortex (MPFC) are associated with HA or NS scores, although the relation between the power of resting state slow oscillations and these temperament dimensions remains poorly elucidated. This preliminary study investigated the biological bases of these temperament traits by particularly addressing the resting state low-frequency fluctuations in MPFC. Regional hemodynamic changes in channels covering MPFC during 5-min resting states were measured from 22 healthy participants using near-infrared spectroscopy (NIRS). These data were used for correlation analyses. Results show that the power of slow oscillations during resting state around the dorsal part of MPFC is negatively correlated with the HA score. In contrast, NS was positively correlated with the power of resting state slow oscillations around the ventral part of MPFC. These results suggest that the powers of slow oscillation at rest in dorsal or ventral MPFC, respectively, reflect the degrees of HA and NS. This exploratory study therefore uncovers novel neural bases of HA and NS. We discuss a neural mechanism underlying aversion-related and reward-related processing based on results obtained from this study. PMID:24381545

  18. On the Nature of the mHz X-ray Quasi-Periodic Oscillations from Ultraluminous X-ray source M82 X-1: Search for Timing-Spectral Correlations

    NASA Technical Reports Server (NTRS)

    Pasham, Dheeraj R.; Strohmayer, Tod E.

    2013-01-01

    Using all the archival XMM-Newton X-ray (3-10 keV) observations of the ultraluminous X-ray source (ULX) M82 X-1, we searched for a correlation between its variable mHz quasi-periodic oscillation (QPO) frequency and its hardness ratio (5-10 keV/3-5 keV), an indicator of the energy spectral power-law index. When stellar-mass black holes (StMBHs) exhibit type-C low-frequency QPOs (0.2-15 Hz), the centroid frequency of the QPO is known to correlate with the energy spectral index. The detection of such a correlation would strengthen the identification of M82 X-1's mHz QPOs as type-C and enable a more reliable mass estimate by scaling its QPO frequencies to those of type-C QPOs in StMBHs of known mass.We resolved the count rates and the hardness ratios of M82 X-1 and a nearby bright ULX (source 5/X42.3+59) through surface brightness modeling.We detected QPOs in the frequency range of 36-210 mHz during which M82 X-1's hardness ratio varied from 0.42 to 0.47. Our primary results are (1) that we do not detect any correlation between the mHz QPO frequency and the hardness ratio (a substitute for the energy spectral power-law index) and (2) similar to some accreting X-ray binaries, we find that M82 X-1's mHz QPO frequency increases with its X-ray count rate (Pearson's correlation coefficient = +0.97). The apparent lack of a correlation between the QPO centroid frequency and the hardness ratio poses a challenge to the earlier claims that the mHz QPOs of M82 X-1 are the analogs of the type-C low-frequency QPOs of StMBHs. On the other hand, it is possible that the observed relation between the hardness ratio and the QPO frequency represents the saturated portion of the correlation seen in type-C QPOs of StMBHs-in which case M82 X-1's mHz QPOs can still be analogous to type-C QPOs.

  19. Multimode and multistate ladder oscillator and frequency recognition device

    NASA Technical Reports Server (NTRS)

    Aumann, Herbert M. (Inventor)

    1976-01-01

    A ladder oscillator composed of capacitive and inductive impedances connected together to form a ladder network which has a chosen number N oscillation modes at N different frequencies. Each oscillation mode is characterized by a unique standing wave voltage pattern along the nodes of the ladder oscillator, with the mode in which the ladder oscillator is oscillating being determinable from the amplitudes or phase of the oscillations at the nodes. A logic circuit may be connected to the nodes of the oscillator to compare the phases of selected nodes and thereby determine which mode the oscillator is oscillating in. A ladder oscillator composed of passive capacitive and inductive impedances can be utilized as a frequency recognition device, since the passive ladder oscillator will display the characteristic standing wave patterns if an input signal impressed upon the ladder oscillator is close to one of the mode frequencies of the oscillator. A CL ladder oscillator having series capacitive impedances and shunt inductive impedances can exhibit sustained and autonomous oscillations if active nonlinear devices are connected in parallel with the shunt inductive impedances. The active CL ladder oscillator can be synchronized to input frequencies impressed upon the oscillator, and will continue to oscillate after the input signal has been removed at a mode frequency which is, in general, nearest to the input signal frequency. Autonomous oscillations may also be obtained as desired from the active CL ladder oscillator at the mode frequencies.

  20. Brain state-dependent recruitment of high-frequency oscillations in the human hippocampus.

    PubMed

    Billeke, Pablo; Ossandon, Tomas; Stockle, Marcelo; Perrone-Bertolotti, Marcela; Kahane, Philippe; Lachaux, Jean-Philippe; Fuentealba, Pablo

    2017-09-01

    Ripples are high-frequency bouts of coordinated hippocampal activity believed to be crucial for information transfer and memory formation. We used intracortical macroelectrodes to record neural activity in the human hippocampus of awake subjects undergoing surgical treatment for refractory epilepsy and distinguished two populations of ripple episodes based on their frequency spectrum. The phase-coupling of one population, slow ripples (90-110 Hz), to cortical delta oscillations was differentially modulated by cognitive task; whereas the second population, fast ripples (130-170 Hz), was not seemingly correlated to local neural activity. Furthermore, as cognitive tasks changed, the ongoing coordination of neural activity associated to slow ripples progressively augmented along the parahippocampal axis. Thus, during resting states, slow ripples were coordinated in restricted hippocampal territories; whereas during active states, such as attentionally-demanding tasks, high frequency activity emerged across the hippocampus and parahippocampal cortex, that was synchronized with slow ripples, consistent with ripples supporting information transfer and coupling anatomically distant regions. Hence, our results provide further evidence of neural diversity in hippocampal high-frequency oscillations and their association to cognitive processing in humans. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Resting and Task-Modulated High-Frequency Brain Rhythms Measured by Scalp Encephalography in Infants with Tuberous Sclerosis Complex

    ERIC Educational Resources Information Center

    Stamoulis, Catherine; Vogel-Farley, Vanessa; Degregorio, Geneva; Jeste, Shafali S.; Nelson, Charles A.

    2015-01-01

    The electrophysiological correlates of cognitive deficits in tuberous sclerosis complex (TSC) are not well understood, and modulations of neural dynamics by neuroanatomical abnormalities that characterize the disorder remain elusive. Neural oscillations (rhythms) are a fundamental aspect of brain function, and have dominant frequencies in a wide…

  2. Large-amplitude ULF waves at high latitudes

    NASA Astrophysics Data System (ADS)

    Guido, T.; Tulegenov, B.; Streltsov, A. V.

    2014-11-01

    We present results from the statistical study of ULF waves detected by the fluxgate magnetometer in Gakona, Alaska during several experimental campaigns conducted at the High Frequency Active Auroral Research Program (HAARP) facility in years 2011-2013. We analyzed frequencies of ULF waves recorded during 26 strongly disturbed geomagnetic events (substorms) and compared them with frequencies of ULF waves detected during magnetically quiet times. Our analysis demonstrates that the frequency of the waves carrying most of the power in almost all these events is less than 1 mHz. We also analyzed data from the ACE satellite, measuring parameters of the solar wind in the L1 Lagrangian point between Earth and Sun, and found that in several occasions there is a strong correlation between oscillations of the magnetic field in the solar wind and oscillations detected on the ground. We also found several cases when there is no correlation between signals detected on ACE and on the ground. This finding suggests that these frequencies correspond to the fundamental eigenfrequency of the coupled magnetosphere-ionosphere system, and the amplitude of these waves can reach significant magnitude when the system is driven by the external driver (for example, the solar wind) with this particular frequency. When the frequency of the driver does not match the frequency of the system, the waves still are observed, but their amplitudes are much smaller.

  3. Frequency-band signatures of visual responses to naturalistic input in ferret primary visual cortex during free viewing.

    PubMed

    Sellers, Kristin K; Bennett, Davis V; Fröhlich, Flavio

    2015-02-19

    Neuronal firing responses in visual cortex reflect the statistics of visual input and emerge from the interaction with endogenous network dynamics. Artificial visual stimuli presented to animals in which the network dynamics were constrained by anesthetic agents or trained behavioral tasks have provided fundamental understanding of how individual neurons in primary visual cortex respond to input. In contrast, very little is known about the mesoscale network dynamics and their relationship to microscopic spiking activity in the awake animal during free viewing of naturalistic visual input. To address this gap in knowledge, we recorded local field potential (LFP) and multiunit activity (MUA) simultaneously in all layers of primary visual cortex (V1) of awake, freely viewing ferrets presented with naturalistic visual input (nature movie clips). We found that naturalistic visual stimuli modulated the entire oscillation spectrum; low frequency oscillations were mostly suppressed whereas higher frequency oscillations were enhanced. In average across all cortical layers, stimulus-induced change in delta and alpha power negatively correlated with the MUA responses, whereas sensory-evoked increases in gamma power positively correlated with MUA responses. The time-course of the band-limited power in these frequency bands provided evidence for a model in which naturalistic visual input switched V1 between two distinct, endogenously present activity states defined by the power of low (delta, alpha) and high (gamma) frequency oscillatory activity. Therefore, the two mesoscale activity states delineated in this study may define the degree of engagement of the circuit with the processing of sensory input. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Modulating action of low frequency oscillations on high frequency instabilities in Hall thrusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liqiu, Wei, E-mail: weiliqiu@gmail.com, E-mail: weiliqiu@hit.edu.cn; Liang, Han; Ziyi, Yang

    2015-02-07

    It is found that the low frequency oscillations have modulating action on high frequency instabilities in Hall thrusters. The physical mechanism of this modulation is discussed and verified by numerical simulations. Theoretical analyses indicate that the wide-range fluctuations of plasma density and electric field associated with the low frequency oscillations affect the electron drift velocity and anomalous electron transport across the magnetic field. The amplitude and frequency of high frequency oscillations are modulated by low frequency oscillations, which show the periodic variation in the time scale of low frequency oscillations.

  5. NERNST Vortex Potential Of A Genetic Oscillator

    NASA Astrophysics Data System (ADS)

    Garnett, Merrill; Jones, Bill

    The vortex is a dynamic spiral. In molecular biology these have not been reported. We report a vortex compound, with oscillating energy. Toroglobulin (1) transfers 416 mv. to histone. This histone reductase enriches charge in the chromosome in spool proteins around which DNA is coiled. Controlling chromosome charge introduces energetics to gene compression. Impedance spectroscopy shows symmetric oscillations. Specific frequencies show amplitude increases. The Mott-Schottky scans show frequency bands. Histone bands are electronically reduced by Toroglobulin by 416 mv. The Nernst potentials of chemical systems correlate electric gradient to concentration gradients of charged particles. Charge polarization refers to laminar alignment. In formation of the Toroglobulin Ginzburg-Landau vortex, the polarization follows filament curvatures which spiral back on themselves. The magnetic dipoles achieve interactive resonance (esr). This spiral resonator with magnetic interfaces produces the measured Nernst potential.

  6. Multiscale characterization and prediction of monsoon rainfall in India using Hilbert-Huang transform and time-dependent intrinsic correlation analysis

    NASA Astrophysics Data System (ADS)

    Adarsh, S.; Reddy, M. Janga

    2017-07-01

    In this paper, the Hilbert-Huang transform (HHT) approach is used for the multiscale characterization of All India Summer Monsoon Rainfall (AISMR) time series and monsoon rainfall time series from five homogeneous regions in India. The study employs the Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (CEEMDAN) for multiscale decomposition of monsoon rainfall in India and uses the Normalized Hilbert Transform and Direct Quadrature (NHT-DQ) scheme for the time-frequency characterization. The cross-correlation analysis between orthogonal modes of All India monthly monsoon rainfall time series and that of five climate indices such as Quasi Biennial Oscillation (QBO), El Niño Southern Oscillation (ENSO), Sunspot Number (SN), Atlantic Multi Decadal Oscillation (AMO), and Equatorial Indian Ocean Oscillation (EQUINOO) in the time domain showed that the links of different climate indices with monsoon rainfall are expressed well only for few low-frequency modes and for the trend component. Furthermore, this paper investigated the hydro-climatic teleconnection of ISMR in multiple time scales using the HHT-based running correlation analysis technique called time-dependent intrinsic correlation (TDIC). The results showed that both the strength and nature of association between different climate indices and ISMR vary with time scale. Stemming from this finding, a methodology employing Multivariate extension of EMD and Stepwise Linear Regression (MEMD-SLR) is proposed for prediction of monsoon rainfall in India. The proposed MEMD-SLR method clearly exhibited superior performance over the IMD operational forecast, M5 Model Tree (MT), and multiple linear regression methods in ISMR predictions and displayed excellent predictive skill during 1989-2012 including the four extreme events that have occurred during this period.

  7. Consciousness in waking and dreaming: the roles of neuronal oscillation and neuromodulation in determining similarities and differences.

    PubMed

    Kahn, D; Pace-Schott, E F; Hobson, J A

    1997-05-01

    State-dependent aspects of consciousness are explored with particular attention to waking and dreaming. First, those phenomenological differences between waking and dreaming that have been established through subjective reports are reviewed. These differences are robustly expressed in most aspects of consciousness including perception, attention, memory, emotion, orientation, and thought. Next, the roles of high frequency neuronal oscillation and neuromodulation are explored in waking and rapid eye movement sleep, the stage of sleep with which the most intense dreaming is associated. The high frequency neuronal oscillations serve similar functions in the wake and rapid eye movement states sleep but neuromodulation is very different in the two states. The collective high frequency oscillatory activity gives coherence to spatially separate neurons but, because of the different neuromodulation, the binding of sensory input in the wake state is very different from the binding of internally perceived input during rapid eye movement sleep. An explanatory model is presented which states that neuromodulation, as well as input source and brain activation level differentiate states of the brain, while the self-organized collective neuronal oscillations unify consciousness via long range correlations.

  8. Multiple linear regression to estimate time-frequency electrophysiological responses in single trials

    PubMed Central

    Hu, L.; Zhang, Z.G.; Mouraux, A.; Iannetti, G.D.

    2015-01-01

    Transient sensory, motor or cognitive event elicit not only phase-locked event-related potentials (ERPs) in the ongoing electroencephalogram (EEG), but also induce non-phase-locked modulations of ongoing EEG oscillations. These modulations can be detected when single-trial waveforms are analysed in the time-frequency domain, and consist in stimulus-induced decreases (event-related desynchronization, ERD) or increases (event-related synchronization, ERS) of synchrony in the activity of the underlying neuronal populations. ERD and ERS reflect changes in the parameters that control oscillations in neuronal networks and, depending on the frequency at which they occur, represent neuronal mechanisms involved in cortical activation, inhibition and binding. ERD and ERS are commonly estimated by averaging the time-frequency decomposition of single trials. However, their trial-to-trial variability that can reflect physiologically-important information is lost by across-trial averaging. Here, we aim to (1) develop novel approaches to explore single-trial parameters (including latency, frequency and magnitude) of ERP/ERD/ERS; (2) disclose the relationship between estimated single-trial parameters and other experimental factors (e.g., perceived intensity). We found that (1) stimulus-elicited ERP/ERD/ERS can be correctly separated using principal component analysis (PCA) decomposition with Varimax rotation on the single-trial time-frequency distributions; (2) time-frequency multiple linear regression with dispersion term (TF-MLRd) enhances the signal-to-noise ratio of ERP/ERD/ERS in single trials, and provides an unbiased estimation of their latency, frequency, and magnitude at single-trial level; (3) these estimates can be meaningfully correlated with each other and with other experimental factors at single-trial level (e.g., perceived stimulus intensity and ERP magnitude). The methods described in this article allow exploring fully non-phase-locked stimulus-induced cortical oscillations, obtaining single-trial estimate of response latency, frequency, and magnitude. This permits within-subject statistical comparisons, correlation with pre-stimulus features, and integration of simultaneously-recorded EEG and fMRI. PMID:25665966

  9. A Multi-Channel Method for Detecting Periodic Forced Oscillations in Power Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Follum, James D.; Tuffner, Francis K.

    2016-11-14

    Forced oscillations in electric power systems are often symptomatic of equipment malfunction or improper operation. Detecting and addressing the cause of the oscillations can improve overall system operation. In this paper, a multi-channel method of detecting forced oscillations and estimating their frequencies is proposed. The method operates by comparing the sum of scaled periodograms from various channels to a threshold. A method of setting the threshold to specify the detector's probability of false alarm while accounting for the correlation between channels is also presented. Results from simulated and measured power system data indicate that the method outperforms its single-channel counterpartmore » and is suitable for real-world applications.« less

  10. PRSA hydrogen tank thermal acoustic oscillation study

    NASA Technical Reports Server (NTRS)

    Riemer, D. H.

    1979-01-01

    The power reactant storage assembly (PRSA) hydrogen tank test data were reviewed. Two hundred and nineteen data points illustrating the effect of flow rate, temperature ratio and configuration were identified. The test data were reduced to produce the thermal acoustic oscillation parameters. Frequency and amplitude were determined for model correlation. A comparison of PRSA hydrogen tank test data with the analytical models indicated satisfactory agreement for the supply and poor agreement for the full line.

  11. AUTOMATIC FREQUENCY CONTROL SYSTEM

    DOEpatents

    Hansen, C.F.; Salisbury, J.D.

    1961-01-10

    A control is described for automatically matching the frequency of a resonant cavity to that of a driving oscillator. The driving oscillator is disconnected from the cavity and a secondary oscillator is actuated in which the cavity is the frequency determining element. A low frequency is mixed with the output of the driving oscillator and the resultant lower and upper sidebands are separately derived. The frequencies of the sidebands are compared with the secondary oscillator frequency. deriving a servo control signal to adjust a tuning element in the cavity and matching the cavity frequency to that of the driving oscillator. The driving oscillator may then be connected to the cavity.

  12. Prediction of unsteady separated flows on oscillating airfoils

    NASA Technical Reports Server (NTRS)

    Mccroskey, W. J.

    1978-01-01

    Techniques for calculating high Reynolds number flow around an airfoil undergoing dynamic stall are reviewed. Emphasis is placed on predicting the values of lift, drag, and pitching moments. Methods discussed include: the discrete potential vortex method; thin boundary layer method; strong interaction between inviscid and viscous flows; and solutions to the Navier-Stokes equations. Empirical methods for estimating unsteady airloads on oscillating airfoils are also described. These methods correlate force and moment data from wind tunnel tests to indicate the effects of various parameters, such as airfoil shape, Mach number, amplitude and frequency of sinosoidal oscillations, mean angle, and type of motion.

  13. Relationships between hippocampal sharp waves, ripples and fast gamma oscillation: influence of dentate and entorhinal cortical activity

    PubMed Central

    Sullivan, David; Csicsvari, Jozsef; Mizuseki, Kenji; Montgomery, Sean; Diba, Kamran; Buzsáki, György

    2011-01-01

    Summary Hippocampal sharp waves (SPW) and associated fast (‘ripple’) oscillations in the CA1 region are among the most synchronous physiological patterns in the mammalian brain. Using two-dimensional arrays of electrodes for recording local field potentials and unit discharges in freely moving rats, we studied the emergence of ripple oscillations (140–220 Hz) and compared their origin and cellular-synaptic mechanisms with fast gamma oscillations (90–140 Hz). We show that (a) hippocampal SPW-Rs and fast gamma oscillations are quantitatively distinct patterns but involve the same networks and share similar mechanisms, (b) both the frequency and magnitude of fast oscillations is positively correlated with the magnitude of SPWs, (c) during both ripples and fast gamma oscillations the frequency of network oscillation is higher in CA1 than in CA3, (d) SPWs and associated firing of neurons are synchronous in the dorsal hippocampus and dorso-medial entorhinal cortex but ripples are confined to the CA1 pyramidal layer and its downstream targets and (e) the emergence of CA3 population bursts, a prerequisite for SPW-ripples, is biased by activity patterns in the dentate gyrus and entorhinal cortex, with highest probability of ripples associated with an ‘optimum’ level of dentate gamma power. We hypothesize that each hippocampal subnetwork possesses distinct resonant properties, tuned by the magnitude of the excitatory drive. PMID:21653864

  14. Quantum correlation of high dimensional system in a dephasing environment

    NASA Astrophysics Data System (ADS)

    Ji, Yinghua; Ke, Qiang; Hu, Juju

    2018-05-01

    For a high dimensional spin-S system embedded in a dephasing environment, we theoretically analyze the time evolutions of quantum correlation and entanglement via Frobenius norm and negativity. The quantum correlation dynamics can be considered as a function of the decoherence parameters, including the ratio between the system oscillator frequency ω0 and the reservoir cutoff frequency ωc , and the different environment temperature. It is shown that the quantum correlation can not only measure nonclassical correlation of the considered system, but also perform a better robustness against the dissipation. In addition, the decoherence presents the non-Markovian features and the quantum correlation freeze phenomenon. The former is much weaker than that in the sub-Ohmic or Ohmic thermal reservoir environment.

  15. The human brain pacemaker: Synchronized infra-slow neurovascular coupling in patients undergoing non-pulsatile cardiopulmonary bypass.

    PubMed

    Zanatta, Paolo; Toffolo, Gianna Maria; Sartori, Elisa; Bet, Anna; Baldanzi, Fabrizio; Agarwal, Nivedita; Golanov, Eugene

    2013-05-15

    In non-pulsatile cardiopulmonary bypass surgery, middle cerebral artery blood flow velocity (BFV) is characterized by infra-slow oscillations of approximately 0.06Hz, which are paralleled by changes in total EEG power variability (EEG-PV), measured in 2s intervals. Since the origin of these BFV oscillations is not known, we explored their possible causative relationships with oscillations in EEG-PV at around 0.06Hz. We monitored 28 patients undergoing non-pulsatile cardiopulmonary bypass using transcranial Doppler sonography and scalp electroencephalography at two levels of anesthesia, deep (prevalence of burst suppression rhythm) and moderate (prevalence of theta rhythm). Under deep anesthesia, the EEG bursts suppression pattern was highly correlative with BFV oscillations. Hence, a detailed quantitative picture of the coupling between electrical brain activity and BFV was derived, both in deep and moderate anesthesia, via linear and non linear processing of EEG-PV and BFV signals, resorting to widely used measures of signal coupling such as frequency of oscillations, coherence, Granger causality and cross-approximate entropy. Results strongly suggest the existence of coupling between EEG-PV and BFV. In moderate anesthesia EEG-PV mean dominant frequency is similar to frequency of BFV oscillations (0.065±0.010Hz vs 0.045±0.019Hz); coherence between the two signals was significant in about 55% of subjects, and the Granger causality suggested an EEG-PV→BFV causal effect direction. The strength of the coupling increased with deepening anesthesia, as EEG-PV oscillations mean dominant frequency virtually coincided with the BFV peak frequency (0.062±0.017Hz vs 0.060±0.024Hz), and coherence became significant in a larger number (65%) of subjects. Cross-approximate entropy decreased significantly from moderate to deep anesthesia, indicating a higher level of synchrony between the two signals. Presence of a subcortical brain pacemaker that drives vascular infra-slow oscillations in the brain is proposed. These findings allow to suggest an original hypothesis explaining the mechanism underlying infra-slow neurovascular coupling. Copyright © 2013 Elsevier Inc. All rights reserved.

  16. Asymptotic correlation functions and FFLO signature for the one-dimensional attractive Hubbard model

    NASA Astrophysics Data System (ADS)

    Cheng, Song; Jiang, Yuzhu; Yu, Yi-Cong; Batchelor, Murray T.; Guan, Xi-Wen

    2018-04-01

    We study the long-distance asymptotic behavior of various correlation functions for the one-dimensional (1D) attractive Hubbard model in a partially polarized phase through the Bethe ansatz and conformal field theory approaches. We particularly find the oscillating behavior of these correlation functions with spatial power-law decay, of which the pair (spin) correlation function oscillates with a frequency ΔkF (2 ΔkF). Here ΔkF = π (n↑ -n↓) is the mismatch in the Fermi surfaces of spin-up and spin-down particles. Consequently, the pair correlation function in momentum space has peaks at the mismatch k = ΔkF, which has been observed in recent numerical work on this model. These singular peaks in momentum space together with the spatial oscillation suggest an analog of the Fulde-Ferrell-Larkin-Ovchinnikov (FFLO) state in the 1D Hubbard model. The parameter β representing the lattice effect becomes prominent in critical exponents which determine the power-law decay of all correlation functions. We point out that the backscattering of unpaired fermions and bound pairs within their own Fermi points gives a microscopic origin of the FFLO pairing in 1D.

  17. Contribution of inter-muscular synchronization in the modulation of tremor intensity in Parkinson's disease.

    PubMed

    He, Xin; Hao, Man-Zhao; Wei, Ming; Xiao, Qin; Lan, Ning

    2015-12-01

    Involuntary central oscillations at single and double tremor frequencies drive the peripheral neuromechanical system of muscles and joints to cause tremor in Parkinson's disease (PD). The central signal of double tremor frequency was found to correlate more directly to individual muscle EMGs (Timmermann et al. 2003). This study is aimed at investigating what central components of oscillation contribute to inter-muscular synchronization in a group of upper extremity muscles during tremor in PD patients. 11 idiopathic, tremor dominant PD subjects participated in this study. Joint kinematics during tremor in the upper extremity was recorded along with EMGs of six upper arm muscles using a novel experimental apparatus. The apparatus provided support for the upper extremity on a horizontal surface with reduced friction, so that resting tremor in the arm can be recorded with a MotionMonitor II system. In each subject, the frequencies of rhythmic firings in upper arm muscles were determined using spectral analysis. Paired and pool-averaged coherence analyses of EMGs for the group of muscles were performed to correlate the level of inter-muscular synchronization to tremor amplitudes at shoulder and elbow. The phase shift between synchronized antagonistic muscle pairs was calculated to aid coherence analysis in the muscle pool. Recorded EMG revealed that rhythmic firings were present in most recorded muscles, which were either synchronized to form phase-locked bursting cycles at a subject specific frequency, or unsynchronized with a random phase distribution. Paired coherence showed a stronger synchronization among a subset of recorded arm muscles at tremor frequency than that at double tremor frequency. Furthermore, the number of synchronized muscles in the arm was positively correlated to tremor amplitudes at elbow and shoulder. Pool-averaged coherence at tremor frequency also showed a better correlation with the amplitude of resting tremor than that of double tremor frequency, indicating that the neuromechanical coupling in peripheral neuromuscular system was stronger at tremor frequency. Both paired and pool-averaged coherences are more consistent indexes to correlate to tremor intensity in a group of upper extremity muscles of PD patients. The central drive at tremor frequency contributes mainly to synchronize peripheral muscles in the modulation of tremor intensity.

  18. Many-body and spin-orbit aspects of the alternating current phenomena

    NASA Astrophysics Data System (ADS)

    Glenn, Rachel M.

    The thesis reports on research in the general field of light interaction with matter. According to the topics addressed, it can be naturally divided into two parts: Part I, many-body aspects of the Rabi oscillations which a two-level systems undergoes under a strong resonant drive; and Part II, absorption of the ac field between the spectrum branches of two-dimensional fermions that are split by the combined action of Zeeman and spin-orbit (SO) fields. The focus of Part I is the following many-body effects that modify the conventional Rabi oscillations: Chapter 1, coupling of a two-level system to a single vibrational mode of the environment. Chapter 2, correlated Rabi oscillations in two electron-hole systems coupled by tunneling with strong electron-hole attraction. In Chapter 1, a new effect of Rabi-vibronic resonance is uncovered. If the frequency of the Rabi oscillations, OR, is close to the frequency o0 of the vibrational mode, the oscillations acquire a collective character. It is demonstrated that the actual frequency of the collective oscillations exhibits a bistable behavior as a function of OR - o0. The main finding in Chapter 2 is, that the Fourier spectrum of the Rabi oscillations in two coupled electron-hole systems undergoes a strong transformation with increasing O R. For OR smaller than the tunneling frequency, the spectrum is dominated by a low-frequency (<< OR ) component and contains two additional weaker lines; conventional Rabi oscillations are restored only as OR exceeds the electron-hole attraction strength. The highlight of Part II is a finding that, while the spectrum of absorption between either Zeeman-split branches or SO-split branches is close to a delta-peak, in the presence of both, it transforms into a broad line with singular behavior at the edges. In particular, when the magnitudes of Zeeman and SO are equal, absorption of very low (much smaller than the splitting) frequencies become possible. The shape of the absorption spectrum is highly anisotropic with respect to the exciting field. This peculiar behavior of the absorption is also studied in wire geometry, where the interplay between two couplings (Zeeman and spin-orbit splitting) affects the shape of numerous absorption peaks.

  19. Variational treatment of entanglement in the Dicke model

    NASA Astrophysics Data System (ADS)

    Bakemeier, L.; Alvermann, A.; Fehske, H.

    2015-10-01

    We introduce a variational ansatz for the Dicke model that extends mean-field theory through the inclusion of spin-oscillator correlations. The correlated variational state is obtained from the mean-field product state via a unitary transformation. The ansatz becomes correct in the limit of large oscillator frequency and in the limit of a large spin, for which it captures the leading quantum corrections to the classical limit exactly including the spin-oscillator entanglement entropy. We explain the origin of the unitary transformation before we show that the ansatz improves substantially upon mean-field theory, giving near exact results for the ground state energy and very good results for other observables. We then discuss why the ansatz still encounters problems in the transition regime at moderate spin lengths, where it fails to capture the precursors of the superradiant quantum phase transition faithfully. This observation illustrates the principal limits of semi-classical formulations, even after they are extended with correlations and entanglement.

  20. Frequency dependence and frequency control of microbubble streaming flows

    NASA Astrophysics Data System (ADS)

    Wang, Cheng; Rallabandi, Bhargav; Hilgenfeldt, Sascha

    2013-02-01

    Steady streaming from oscillating microbubbles is a powerful actuating mechanism in microfluidics, enjoying increased use due to its simplicity of manufacture, ease of integration, low heat generation, and unprecedented control over the flow field and particle transport. As the streaming flow patterns are caused by oscillations of microbubbles in contact with walls of the set-up, an understanding of the bubble dynamics is crucial. Here we experimentally characterize the oscillation modes and the frequency response spectrum of such cylindrical bubbles, driven by a pressure variation resulting from ultrasound in the range of 1 kHz raisebox {-.9ex{stackrel{textstyle <}{˜ }} }f raisebox {-.9ex{stackrel{textstyle <}{˜ }} } 100 kHz. We find that (i) the appearance of 2D streaming flow patterns is governed by the relative amplitudes of bubble azimuthal surface modes (normalized by the volume response), (ii) distinct, robust resonance patterns occur independent of details of the set-up, and (iii) the position and width of the resonance peaks can be understood using an asymptotic theory approach. This theory describes, for the first time, the shape oscillations of a pinned cylindrical bubble at a wall and gives insight into necessary mode couplings that shape the response spectrum. Having thus correlated relative mode strengths and observed flow patterns, we demonstrate that the performance of a bubble micromixer can be optimized by making use of such flow variations when modulating the driving frequency.

  1. Subsonic roll oscillation experiments on the Standard Dynamics Model

    NASA Technical Reports Server (NTRS)

    Beyers, M. E.

    1983-01-01

    The experimental determination of the subsonic roll derivatives of the Standard Dynamics Model, which is representative of a current fighter aircraft configuration, is described. The direct, cross and cross-coupling derivatives are presented for angles of attack up to 41 deg and sideslip angles in the range from -5 deg to 5 deg, as functions of oscillation frequency. The derivatives exhibited significant nonlinear trends at high incidences and were found to be extremely sensitive to sideslip angle at angles of attack near 36 deg. The roll damping and dynamic cross derivatives were highly frequency dependent at angles of attack above 30 deg. The highest values measured for the dynamic cross and cross-coupling derivatives were comparable in magnitude with the maximum roll damping. The effects of oscillation amplitude and Mach number were also investigated, and the direct derivatives were correlated with data from another facility.

  2. Are there intracellular Ca2+ oscillations correlated with flagellar beating in human sperm? A three vs. two-dimensional analysis.

    PubMed

    Corkidi, G; Montoya, F; Hernández-Herrera, P; Ríos-Herrera, W A; Müller, M F; Treviño, C L; Darszon, A

    2017-09-01

    Are there intracellular Ca2+ ([Ca2+]i) oscillations correlated with flagellar beating in human sperm? The results reveal statistically significant [Ca2+]i oscillations that are correlated with the human sperm flagellar beating frequency, when measured in three-dimensions (3D). Fast [Ca2+]i oscillations that are correlated to the beating flagellar frequency of cells swimming in a restricted volume have been detected in hamster sperm. To date, such findings have not been confirmed in any other mammalian sperm species. An important question that has remained regarding these observations is whether the fast [Ca2+]i oscillations are real or might they be due to remaining defocusing effects of the Z component arising from the 3D beating of the flagella. Healthy donors whose semen samples fulfill the WHO criteria between the age of 18-28 were selected. Cells from at least six different donors were utilized for analysis. Approximately the same number of experimental and control cells were analyzed. Motile cells were obtained by the swim-up technique and were loaded with Fluo-4 (Ca2+ sensitive dye) or with Calcein (Ca2+ insensitive dye). Ni2+ was used as a non-specific plasma membrane Ca2+ channel blocker. Fluorescence data and flagella position were acquired in 3D. Each cell was recorded for up to 5.6 s within a depth of 16 microns with a high speed camera (coupled to an image intensifier) acquiring at a rate of 3000 frames per second, while an oscillating objective vibrated at 90 Hz via a piezoelectric device. From these samples, eight experimental and nine control sperm cells were analyzed in both 2D and 3D. We have implemented a new system that allows [Ca2+]i measurements of the human sperm flagellum beating in 3D. These measurements reveal statistically significant [Ca2+]i oscillations that correlate with the flagellar beating frequency. These oscillations may arise from intracellular sources and/or Ca2+ transporters, as they were insensitive to external Ni2+, a non-specific plasma membrane Ca2+ channel blocker. N/A. Analysis in 3D needs a very fast image acquisition rate to correctly sample a volume containing swimming sperm. This condition requires a very short exposure time per image making it necessary to use an image intensifier which also increases noise. The lengthy analysis time required to obtain reliable results limited the number of cells that could be analyzed. The possibility of recording flagellar [Ca2+]i oscillations described here may open a new avenue to better understand ciliary and flagellar beating that are fundamental for mucociliary clearance, oocyte transport, fertilization, cerebrospinal fluid pressure regulation and developmental left-right symmetry breaking in the embryonic node. This work was supported by Consejo Nacional de Ciencia y Tecnología (CONACyT) (grants 253952 to G.C.; 156667 to F.M.M. and Fronteras 71 39908-Q to A.D. and Post-doctoral scholarships 366844 to P.H.-H. and 291028 to F.M.) and the Dirección General de Asuntos del Personal Académico of the Universidad Nacional Autónoma de México (DGAPA-UNAM) (grants CJIC/CTIC/4898/2016 to F.M. and IN205516 to A.D.). There are no conflicts of interest to declare. © The Author 2017. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  3. Oscillation Mode Variability in Evolved Compact Pulsators from Kepler Photometry. I. The Hot B Subdwarf Star KIC 3527751

    NASA Astrophysics Data System (ADS)

    Zong, Weikai; Charpinet, Stéphane; Fu, Jian-Ning; Vauclair, Gérard; Niu, Jia-Shu; Su, Jie

    2018-02-01

    We present the first results of an ensemble and systematic survey of oscillation mode variability in pulsating hot B subdwarf (sdB) and white dwarf stars observed with the original Kepler mission. The satellite provides uninterrupted high-quality photometric data with a time baseline that can reach up to 4 yr collected on pulsating stars. This is a unique opportunity to characterize long-term behaviors of oscillation modes. A mode modulation in amplitude and frequency can be independently inferred by its fine structure in the Fourier spectrum, from the sLSP, or with prewhitening methods applied to various parts of the light curve. We apply all these techniques to the sdB star KIC 3527751, a long-period-dominated hybrid pulsator. We find that all the detected modes with sufficiently large amplitudes to be thoroughly studied show amplitude and/or frequency variations. Components of three identified quintuplets around 92, 114, and 253 μHz show signatures that can be linked to nonlinear interactions according to the resonant mode coupling theory. This interpretation is further supported by the fact that many oscillation modes are found to have amplitudes and frequencies showing correlated or anticorrelated variations, a behavior that can be linked to the amplitude equation formalism, where nonlinear frequency corrections are determined by their amplitude variations. Our results suggest that oscillation modes varying with diverse patterns are a very common phenomenon in pulsating sdB stars. Close structures around main frequencies therefore need to be carefully interpreted in light of this finding to secure a robust identification of real eigenfrequencies, which is crucial for seismic modeling. The various modulation patterns uncovered should encourage further developments in the field of nonlinear stellar oscillation theory. It also raises a warning to any long-term project aiming at measuring the rate of period change of pulsations caused by stellar evolution, or at discovering stellar (planetary) companions around pulsating stars using timing methods, as both require very stable pulsation modes.

  4. Turbulent Boundary Layers in Oscillating Flows. Part 1: an Experimental and Computational Study

    NASA Technical Reports Server (NTRS)

    Cook, W. J.

    1986-01-01

    An experimental-computational study of the behavior of turbulent boundary layers for oscillating air flows over a plane surface with a small favorable mean pressure gradient is described. Experimental studies were conducted for boundary layers generated on the test section wall of a facility that produces a flow with a mean free stream velocity and a superposed nearly-pure sinusoidal component over a wide range of frequency. Flow at a nominal mean free stream velocity of 50 m/s were studied at atmospheric pressure and temperature at selected axial positions over a 2 m test length for frequencies ranging from 4 to 29 Hz. Quantitative experimental results are presented for unsteady velocity profiles and longitudinal turbulence levels obtained from hot wire anemometer measurements at three axial positions. Mean velocity profiles for oscillating flows were found to exhibit only small deviations from corresponding steady flow profiles, while amplitudes and phase relationships exhibited a strong dependence on axial position and frequency. Since sinusoidal flows could be generated over a wide range of frequency, studies at fixed values of reduced frequency at different axial positions were studied. Results show that there is some utility in the use of reduced frequency to correlate unsteady velocity results. The turbulence level u' sub rms was observed to vary essentially sinusoidally around values close to those measured in steady flow. However, the amplitude of oscillation and phase relations for turbulence level were found to be strongly frequency dependent. Numerical predictions were obtained using an unsteady boundary layer computational code and the Cebeci-Smith and Glushko turbulence models. Predicted quantities related to unsteady velocity profiles exhibit fair agreement with experiment when the Cebeci-Smith turbulence model is used.

  5. Circuit oscillations in odor perception and memory.

    PubMed

    Kay, Leslie M

    2014-01-01

    Olfactory system neural oscillations as seen in the local field potential have been studied for many decades. Recent research has shown that there is a functional role for the most studied gamma oscillations (40-100Hz in rats and mice, and 20Hz in insects), without which fine odor discrimination is poor. When these oscillations are increased artificially, fine discrimination is increased, and when rats learn difficult and highly overlapping odor discriminations, gamma is increased in power. Because of the depth of study on this oscillation, it is possible to point to specific changes in neural firing patterns as represented by the increase in gamma oscillation amplitude. However, we know far less about the mechanisms governing beta oscillations (15-30Hz in rats and mice), which are best associated with associative learning of responses to odor stimuli. These oscillations engage every part of the olfactory system that has so far been tested, plus the hippocampus, and the beta oscillation frequency band is the one that is most reliably coherent with other regions during odor processing. Respiratory oscillations overlapping with the theta frequency band (2-12Hz) are associated with odor sniffing and normal breathing in rats. They also show coupling in some circumstances between olfactory areas and rare coupling between the hippocampus and olfactory bulb. The latter occur in specific learning conditions in which coherence strength is negatively or positively correlated with performance, depending on the task. There is still much to learn about the role of neural oscillations in learning and memory, but techniques that have been brought to bear on gamma oscillations (current source density, computational modeling, slice physiology, behavioral studies) should deliver much needed knowledge of these events. © 2014 Elsevier B.V. All rights reserved.

  6. Movement-related beta oscillations show high intra-individual reliability.

    PubMed

    Espenhahn, Svenja; de Berker, Archy O; van Wijk, Bernadette C M; Rossiter, Holly E; Ward, Nick S

    2017-02-15

    Oscillatory activity in the beta frequency range (15-30Hz) recorded from human sensorimotor cortex is of increasing interest as a putative biomarker of motor system function and dysfunction. Despite its increasing use in basic and clinical research, surprisingly little is known about the test-retest reliability of spectral power and peak frequency measures of beta oscillatory signals from sensorimotor cortex. Establishing that these beta measures are stable over time in healthy populations is a necessary precursor to their use in the clinic. Here, we used scalp electroencephalography (EEG) to evaluate intra-individual reliability of beta-band oscillations over six sessions, focusing on changes in beta activity during movement (Movement-Related Beta Desynchronization, MRBD) and after movement termination (Post-Movement Beta Rebound, PMBR). Subjects performed visually-cued unimanual wrist flexion and extension. We assessed Intraclass Correlation Coefficients (ICC) and between-session correlations for spectral power and peak frequency measures of movement-related and resting beta activity. Movement-related and resting beta power from both sensorimotor cortices was highly reliable across sessions. Resting beta power yielded highest reliability (average ICC=0.903), followed by MRBD (average ICC=0.886) and PMBR (average ICC=0.663). Notably, peak frequency measures yielded lower ICC values compared to the assessment of spectral power, particularly for movement-related beta activity (ICC=0.386-0.402). Our data highlight that power measures of movement-related beta oscillations are highly reliable, while corresponding peak frequency measures show greater intra-individual variability across sessions. Importantly, our finding that beta power estimates show high intra-individual reliability over time serves to validate the notion that these measures reflect meaningful individual differences that can be utilised in basic research and clinical studies. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  7. Power spectrum, growth velocities and cross-correlations of longitudinal and transverse oscillations of individual Nicotiana tabacum pollen tube.

    PubMed

    Haduch-Sendecka, Aleksandra; Pietruszka, Mariusz; Zajdel, Paweł

    2014-08-01

    We report on our results concerning growth rate and oscillation modes of the individual pollen tube apex. The observed volumetric growth and growth rate periodicity in the longitudinal (axial) direction are accompanied by transverse oscillations with similar frequencies but higher energies than the axial modes. Examination of the time-domain coherence between oscillations in mutually perpendicular directions revealed minimal energy dissipation in the unperturbed (isotonic) case, opposite to the two remaining cases (hypertonic, hypotonic) with notable correlations. We conjecture that the minimal energy loss is therefore optimal in the natural growth conditions. The longitudinal growth velocity is also found to be the fastest in the unperturbed case. As a result, the isolated system (pollen tube tip) is conserving energy by transforming it from elastic potential energy of extending apical wall to the kinetic energy of periodical motion. The energy dissipation is found to be about 20 % smaller in axial direction than in lateral one, indicating that the main energy consumption is dedicated to the elongation. We further observe that the hypertonic spectrum is shifted towards lower and the hypotonic towards higher frequencies with respect to the isotonic spectrum. In consequence, the turgor pressure inside the growing cell influences monotonically the frequency of both modes of oscillations. The calculated power spectrum seen as a measure of the overall energy efficiency of tip growth under hypertonic, hypotonic and isotonic conditions implies that the biochemistry has been fine tuned to be optimal under normal growth conditions, which is the developmental implication of this work. A simple theoretical extension of the Ortega equation is derived and analysed with respect to its contribution to power spectrum. We show that the plastic term, related to the effective turgor pressure, with maximum contribution at frequency f = 0 is responsible for the steady growth. In turn, the elastic contribution dependent on the time derivative of pressure fluctuations tends to move the system into oscillatory mode (f > 0). None of those mechanisms is privileged over another. The coupling mechanism is naturally generated through a convolution of those two terms and will decide about the overall character of the growth for each particular case.

  8. Influence of the oscillation frequency of different side-to-side toothbrushes on noncontact biofilm removal.

    PubMed

    Schmidt, Julia C; Astasov-Frauenhoffer, Monika; Waltimo, Tuomas; Weiger, Roland; Walter, Clemens

    2018-01-22

    The objective of this study was to investigate the influence of different oscillation frequencies of three powered toothbrushes with side-to-side action for noncontact biofilm removal in an artificial interdental space model. A three-species biofilm (Porphyromonas gingivalis, Fusobacterium nucleatum and Streptococcus sanguinis) was formed in vitro on protein-coated titanium disks using a flow chamber system combined with a static biofilm growth model. The oscillation frequencies of three commercial side-to-side toothbrushes were evaluated by means of a dose response. The frequency was decreased in steps (100, 85, 70, 55, and 40%). Subsequently, the biofilm-coated substrates were exposed to the side-to-side toothbrushes. The biofilm volumes were measured using volumetric analyses (Imaris 8.1.2) with confocal laser scanning microscope images (Zeiss LSM700). Compared to maximum oscillation frequency (100%), lower oscillation frequencies (up to 40%) resulted in reduced median percentages of biofilm reduction (median biofilm reduction up to 53% for maximum oscillation frequency, and up to 13% for 40% oscillation frequency) (p ≥ 0.03). In addition, decreasing the oscillation frequencies of the side-to-side toothbrushes showed an enhanced variety in the results of repeated experiments. The oscillation frequency of the tested side-to-side toothbrushes affected the biofilm reduction in an interdental space model. Within a toothbrush, higher oscillation frequencies may lead to beneficial effects on interdental biofilm removal by noncontact brushing.

  9. Relationships between interdecadal variability and extreme precipitation events in South America during the monsoon season

    NASA Astrophysics Data System (ADS)

    Grimm, Alice; Laureanti, Nicole; Rodakoviski, Rodrigo

    2016-04-01

    This study aims to clarify the impact of interdecadal climate oscillations (periods of 8 years and longer) on the frequency of extreme precipitation events over South America in the monsoon season (austral spring and summer), and determine the influence of these oscillations on the daily precipitation frequency distribution. Interdecadal variability modes of precipitation during the monsoon season are provided by a continental-scale rotated empirical orthogonal function analysis for the 60 years period 1950-2009. The main disclosed modes are robust, since they are reproduced for different periods. They can produce differences around 50% in monthly precipitation between opposite phases. Oceanic and atmospheric anomalous fields associated with these modes indicate that they have physical basis. The first modes in spring and summer display highest correlation with the Interdecadal Pacific Oscillation (IPO) SST mode, while the second modes have strongest correlation with the Atlantic Multidecadal Oscillation (AMO) SST mode. However, there are also other influences on these modes. As the most dramatic consequences of climate variability stem from its influence on the frequency of extreme precipitation events, it is important to also assess this influence, since variations in monthly or seasonal precipitation do not necessarily imply significant alterations in their extreme events. This study seeks to answer the questions: i) Do opposite phases of the main interdecadal modes of seasonal precipitation produce significant anomalies in the frequency of extreme events? ii) Does the interdecadal variability of the frequency of extreme events show similar spatial and temporal structure as the interdecadal variability of the seasonal precipitation? iii) Does the interdecadal variability change the daily precipitation probability distribution between opposite phases? iv) In this case, which ranges of daily precipitation are most affected? The significant anomalies of the extreme events frequency in opposite phases of the interdecadal oscillations display spatial patterns very similar to those of the corresponding modes. In addition, the modes of extreme events frequency bear similarity to the modes of seasonal precipitation, although a complete assessment of this similarity is not possible with the daily data available. The Kolmogorov-Smirnov test is applied to the daily precipitation series for positive and negative phases of the interdecadal modes, in regions with high factor loadings. It shows, with significance level better than 0.01, that daily precipitation from opposite phases pertains to different frequency distributions. Further analyses disclose clearly that there is much greater relative impact of the interdecadal oscillations on the extreme ranges of daily rainfall than in the ranges of moderate and light rainfall. This impact is more linear is spring than in summer. Acknowledgments: This work was supported by: Inter-American Institute for Global Change Research (IAI) CRN3035 which is supported by the US National Science Foundation (Grant GEO-1128040), European Community's Seventh Framework Programme under Grant Agreement n° 212492 (CLARIS LPB), and CNPq-Brazil (National Council for Scientific and Technologic Development).

  10. Oscillating load-induced acoustic emission in laboratory experiment

    USGS Publications Warehouse

    Ponomarev, Alexander; Lockner, David A.; Stroganova, S.; Stanchits, S.; Smirnov, Vladmir

    2010-01-01

    Spatial and temporal patterns of acoustic emission (AE) were studied. A pre-fractured cylinder of granite was loaded in a triaxial machine at 160 MPa confining pressure until stick-slip events occurred. The experiments were conducted at a constant strain rate of 10−7 s−1 that was modulated by small-amplitude sinusoidal oscillations with periods of 175 and 570 seconds. Amplitude of the oscillations was a few percent of the total load and was intended to simulate periodic loading observed in nature (e.g., earth tides or other sources). An ultrasonic acquisition system with 13 piezosensors recorded acoustic emissions that were generated during deformation of the sample. We observed a correlation between AE response and sinusoidal loading. The effect was more pronounced for higher frequency of the modulating force. A time-space spectral analysis for a “point” process was used to investigate details of the periodic AE components. The main result of the study was the correlation of oscillations of acoustic activity synchronized with the applied oscillating load. The intensity of the correlated AE activity was most pronounced in the “aftershock” sequences that followed large-amplitude AE events. We suggest that this is due to the higher strain-sensitivity of the failure area when the sample is in a transient, unstable mode. We also found that the synchronization of AE activity with the oscillating external load nearly disappeared in the period immediately after the stick-slip events and gradually recovered with further loading.

  11. Stimulus-dependent modulation of spontaneous low-frequency oscillations in the rat visual cortex.

    PubMed

    Huang, Liangming; Liu, Yadong; Gui, Jianjun; Li, Ming; Hu, Dewen

    2014-08-06

    Research on spontaneous low-frequency oscillations is important to reveal underlying regulatory mechanisms in the brain. The mechanism for the stimulus modulation of low-frequency oscillations is not known. Here, we used the intrinsic optical imaging technique to examine stimulus-modulated low-frequency oscillation signals in the rat visual cortex. The stimulation was presented monocularly as a flashing light with different frequencies and intensities. The phases of low-frequency oscillations in different regions tended to be synchronized and the rhythms typically accelerated within a 30-s period after stimulation. These phenomena were confined to visual stimuli with specific flashing frequencies (12.5-17.5 Hz) and intensities (5-10 mA). The acceleration and synchronization induced by the flashing frequency were more marked than those induced by the intensity. These results show that spontaneous low-frequency oscillations can be modulated by parameter-dependent flashing lights and indicate the potential utility of the visual stimulus paradigm in exploring the origin and function of low-frequency oscillations.

  12. Spectral Index and Quasi-Periodic Oscillation Frequency Correlation in Black Hole (BH) Sources: Observational Evidence of Two Phases and Phase Transition in BHs

    NASA Technical Reports Server (NTRS)

    Titarchuk, Lev; Fiorito, Ralph

    2004-01-01

    Recent studies have shown that strong correlations are observed between the low frequencies (1-10 Hz) of quasiperiodic oscillations (QPOs) and the spectral power law index of several Black Hole (BH) candidate sources, in low hard states, steep power-law (soft) states and in transition between these states. The observations indicate that the X-ray spectrum of such state (phases) show the presence of a power-law component and are sometimes related to simultaneous radio emission indicated the probable presence of a jet. Strong QPOs (less than 20% rms) are present in the power density spectrum in the spectral range where the power-law component is dominant ( i.e. 60-90% ). This evidence contradicts the dominant long standing interpretation of QPOs as a signature of the thermal accretion disk. We present the data from the literature and our own data to illustrate the dominance of power-law index-QPO frequency correlations. We provide a model, that identifies and explains the origin of the QPOs and how they are imprinted on the properties of power-law flux component. We argue the existence of a bounded compact coronal region which is a natural consequence of the adjustment of Keplerian disk flow to the innermost sub-Keplerian boundary conditions near the central object and that ultimately leads to the formation of a transition layer (TL) between the adjustment radius and the innermost boundary. The model predicts two phases or states dictated by the photon upscattering produced in the TL: (1) hard state, in which the TL is optically thin and very hot (kT approx. greater than 50 keV) producing photon upscattering via thermal Componization; the photon spectrum index Gamma appprox.1.5 for this state is dictated by gravitational energy release and Compton cooling in an optically thin shock near the adjustment radius; (2) a soft state which is optically thick and relatively cold (approx. less than 5 keV); the index for this state, Gamma approx. 2.8 is determined by soft-photon upscattering and photon trapping in converging flow into BH. In the TL model for corona the QPO frequency vnu(sub high) is related to the gravitational (close to Keplerian) frequency nu(sub K) at the outer (adjustment) radius and nu(sub low) is related to the TL s normal mode (magnetoacoustic) oscillation frequency nu(sub MA). The observed correlations between index and low and high QPO frequencies are readily explained in terms of this model. We also suggest a new method for evaluation of the BH mass using the index-frequency correlation.

  13. Spectral Index and Quasi-Periodic Oscillation Frequency Correlation in Black Hole Sources: Observational Evidence of Two Phases and Phase Transition in Black Holes

    NASA Technical Reports Server (NTRS)

    Titarchuk, Lev; Fiorito, Ralph

    2004-01-01

    Recent studies have shown that strong correlations are observed between the low frequencies (1-10 Hz) of quasi-periodic oscillations (QPOs) and the spectral power law index of several black hole (BH) candidate sources, in low (hard) states, steep power law (soft) states, and transitions between these states. The observations indicate that the X-ray spectra of such state (phases) show the presence of a power-law component and are sometimes related to simultaneous radio emission, indicating the probable presence of a jet. Strong QPOs (>20% rms) are present in the power density spectrum in the spectral range where the power-law component is dominant (i.e., 60%90%). This evidence contradicts the dominant, long-standing interpretation of QPOs as a signature of the thermal accretion disk. We present the data from the literature and our own data to illustrate the dominance of power-law index-QPO frequency correlations. We provide a model that identifies and explains the origin of the QPOs and how they are imprinted on the properties of the power-law flux component. We argue for the existence of a bounded compact coronal region that is a natural consequence of the adjustment of the Keplerian disk flow to the innermost sub-Keplerian boundary conditions near the central object and that ultimately leads to the formation of a transition layer (TL) between the adjustment radius and the innermost boundary. The model predicts two phases or states dictated by the photon upscattering produced in the TL: (1) a hard state, in which the TL is optically thin and very hot (kT approximately greater than 50 keV), producing photon upscattering via thermal Comptonization (the photon spectrum index Gamma approximates 1.7 for this state is dictated by gravitational energy release and Compton cooling in an optically thin shock near the adjustment radius), and (2) a soft state that is optically thick and relatively cold (kT approximately less than 5 keV the index for this state, Gamma approximates 2.8, is determined by soft-photon upscattering and photon trapping in a converging flow into the BH). In the TL model for the corona, the QPO frequency V(sub high) is related to the gravitational (close to Keplerian) frequency V(sub K) at the outer (adjustment) radius and v(sub low) is related to the TL's normal mode (magnetoacoustic) oscillation frequency v(sub MA) . The observed correlations between index and low and high QPO frequencies are readily explained in terms of this model. We also suggest a new method for evaluation of the BH mass using the index-frequency correlation.

  14. Mutual 3:1 subharmonic synchronization in a micromachined silicon disk resonator

    NASA Astrophysics Data System (ADS)

    Taheri-Tehrani, Parsa; Guerrieri, Andrea; Defoort, Martial; Frangi, Attilio; Horsley, David A.

    2017-10-01

    We demonstrate synchronization between two intrinsically coupled oscillators that are created from two distinct vibration modes of a single micromachined disk resonator. The modes have a 3:1 subharmonic frequency relationship and cubic, non-dissipative electromechanical coupling between the modes enables their two frequencies to synchronize. Our experimental implementation allows the frequency of the lower frequency oscillator to be independently controlled from that of the higher frequency oscillator, enabling study of the synchronization dynamics. We find close quantitative agreement between the experimental behavior and an analytical coupled-oscillator model as a function of the energy in the two oscillators. We demonstrate that the synchronization range increases when the lower frequency oscillator is strongly driven and when the higher frequency oscillator is weakly driven. This result suggests that synchronization can be applied to the frequency-selective detection of weak signals and other mechanical signal processing functions.

  15. A very high frequency radio interferometer for investigating ionospheric disturbances using geostationary satellites. Determination of changes in exospheric electron content by a comparison of group delay and Faraday rotation

    NASA Technical Reports Server (NTRS)

    Terry, R.; Flaherty, B. J.; Dubroff, R. E.

    1972-01-01

    The theory and development of a VHF correlation radio interferometer for investigating ionospheric disturbances are discussed. The system was developed to receive signals from the geostationary Applications Technology Satellites. Amplitude and phase variations of the signal passing through the ionosphere can be detected by this instrument. The system consists of two superheterodyne receivers separated by a distance known as the baseline of the system. Since the system is a phase sensitive instrument, the local oscillators of the two receivers must be phase coherent. This is accomplished by using phase-locked loops for generating the local oscillators. The two signals from the separate receivers are cross-correlated by multiplying the two signals together and then time averaging the result. The sensitivity of the instrument is increased by off-setting one of the local oscillators by a small amount.

  16. Spherical ion oscillations in a positive polarity gridded inertial-electrostatic confinement device

    NASA Astrophysics Data System (ADS)

    Bandara, R.; Khachan, J.

    2013-07-01

    A pulsed, positive polarity gridded inertial electrostatic confinement device has been investigated experimentally, using a differential emissive probe and potential traces as primary diagnostics. Large amplitude oscillations in the plasma current and plasma potential were observed within a microsecond of the discharge onset, which are indicative of coherent ion oscillations about a temporarily confined excess of recirculating electron space charge. The magnitude of the depth of the potential well in the established virtual cathode was determined using a differential emissive Langmuir probe, which correlated well to the potential well inferred from the ion oscillation frequency for both hydrogen and argon experiments. It was found that the timescale for ion oscillation dispersion is strongly dependent on the neutral gas density, and weakly dependent on the peak anode voltage. The cessation of the oscillations was found to be due to charge exchange processes converting ions to high velocity neutrals, causing the abrupt de-coherence of the oscillations through an avalanche dispersion in phase space.

  17. How to Distinguish Neutron Star and Black Hole X-ray Binaries? Spectral Index and Quasi-Periodic Oscillation Frequency Correlation

    NASA Technical Reports Server (NTRS)

    Titarchuk, Lev; Shaposhnikov, Nickolai

    2005-01-01

    Recent studies have revealed strong correlations between 1-10 Hz frequencies of quasiperiodic oscillations (QPOs) and the spectral power law index of several Black Hole (BH) candidate sources when seen in the low/hard state, the steep power-law (soft) state, and in transition between these states. In the soft state these index-QPO frequency correlations show a saturation of the photon index GAMMA approximately equal to 2.7 at high values of the low frequency nu(sub L). This saturation effect was previously identified as a black hole signature. In this paper we argue that this saturation does not occur, at least for one neutron star (NS) source 4U 1728-34, for which the index GAMMA monotonically increases with nu(sub L) to the values of 6 and higher. We base this conclusion on our analysis of approximately 1.5 Msec of RXTE archival data for 4U 1728-34. We reveal the spectral evolution of the Comptonized blackbody spectra when the source transitions from the hard to soft states. The hard state spectrum is a typical thermal Comptonization spectrum of the soft photons which originate in the disk and the NS outer photospheric layers. The hard state photon index is GAMMA approximately 2. The soft state spectrum consists of two blackbody components which are only slightly Comptonized. Thus we can claim (as expected from theory) that in NS sources thermal equilibrium is established for the soft state. To the contrary in BH sources, the equilibrium is never established due to the presence of the BH horizon. The emergent BH spectrum, even in the high/soft state, has a power law component. We also identify the low QPO frequency nu(sub L) as a fundamental frequency of the quasi-spherical component of the transition layer (presumably related to the corona and the NS and disk magnetic closed field lines). The lower frequency nu(sub SL) is identified as the frequency of oscillations of a quasi-cylindrical configuration of the TL (presumably related to the NS and disk magnetic open field lines). We also show that the presence of Fe K(sub alpha), emission-line strengths, QPOs, and the link between them does not depend on radio flux in 4U 1728-34.

  18. Theory and simulation of ion noise in microwave tubes

    NASA Astrophysics Data System (ADS)

    Manheimer, W. M.; Freund, H. P.; Levush, B.; Antonsen, T. M.

    2001-01-01

    Since there is always some ambient gas in electron beam devices, background ionization is ubiquitous. For long pulse times, the electrostatic potentials associated with this ionization can reach significant levels and give rise to such observed phenomena as phase noise in microwave tubes. This noise is usually associated with the motion of ions in the device; therefore, it is called ion noise. It often manifests itself as a slow phase fluctuation on the output signal. Observations of noise in microwave tubes such as coupled-cavity traveling wave tubes (CC-TWTs) and klystrons have been discussed in the literature. In this paper, a hybrid model is discussed in which the electron beam is described by the beam envelope equation, and the ions generated by beam ionization are treated as discrete particles using the one-dimensional equations of motion. The theoretical model provides good qualitative as well as reasonable quantitative insight into the origin of ion noise phenomena. The numerical results indicate that the model reproduces the salient features of the phase oscillations observed experimentally. That is, the scaling of the frequency of the phase oscillations with gas pressure in the device and the sensitive dependence of the phase oscillations on the focusing magnetic field. Two distinct time scales are observed in simulation. The fastest time scale oscillation is related to the bounce motion of ions in the axial potential wells formed by the scalloping of the electron beam. Slower sawtooth oscillations are observed to correlate with the well-to-well interactions induced by the ion coupling to the electron equilibrium. These oscillations are also correlated with ion dumping to the cathode or collector. As a practical matter, simulations indicate that the low frequency oscillations can be reduced significantly by using a well-matched electron beam propagating from the electron gun into the interaction circuit.

  19. A Comprehensive Analysis of the Correlations between Resting-State Oscillations in Multiple-Frequency Bands and Big Five Traits

    PubMed Central

    Ikeda, Shigeyuki; Takeuchi, Hikaru; Taki, Yasuyuki; Nouchi, Rui; Yokoyama, Ryoichi; Kotozaki, Yuka; Nakagawa, Seishu; Sekiguchi, Atsushi; Iizuka, Kunio; Yamamoto, Yuki; Hanawa, Sugiko; Araki, Tsuyoshi; Miyauchi, Carlos Makoto; Sakaki, Kohei; Nozawa, Takayuki; Yokota, Susumu; Magistro, Daniele; Kawashima, Ryuta

    2017-01-01

    Recently, the association between human personality traits and resting-state brain activity has gained interest in neuroimaging studies. However, it remains unclear if Big Five personality traits are represented in frequency bands (~0.25 Hz) of resting-state functional magnetic resonance imaging (fMRI) activity. Based on earlier neurophysiological studies, we investigated the correlation between the five personality traits assessed by the NEO Five-Factor Inventory (NEO-FFI), and the fractional amplitude of low-frequency fluctuation (fALFF) at four distinct frequency bands (slow-5 (0.01–0.027 Hz), slow-4 (0.027–0.073 Hz), slow-3 (0.073–0.198 Hz) and slow-2 (0.198–0.25 Hz)). We enrolled 835 young subjects and calculated the correlations of resting-state fMRI signals using a multiple regression analysis. We found a significant and consistent correlation between fALFF and the personality trait of extraversion at all frequency bands. Furthermore, significant correlations were detected in distinct brain regions for each frequency band. This finding supports the frequency-specific spatial representations of personality traits as previously suggested. In conclusion, our data highlight an association between human personality traits and fALFF at four distinct frequency bands. PMID:28680397

  20. A Comprehensive Analysis of the Correlations between Resting-State Oscillations in Multiple-Frequency Bands and Big Five Traits.

    PubMed

    Ikeda, Shigeyuki; Takeuchi, Hikaru; Taki, Yasuyuki; Nouchi, Rui; Yokoyama, Ryoichi; Kotozaki, Yuka; Nakagawa, Seishu; Sekiguchi, Atsushi; Iizuka, Kunio; Yamamoto, Yuki; Hanawa, Sugiko; Araki, Tsuyoshi; Miyauchi, Carlos Makoto; Sakaki, Kohei; Nozawa, Takayuki; Yokota, Susumu; Magistro, Daniele; Kawashima, Ryuta

    2017-01-01

    Recently, the association between human personality traits and resting-state brain activity has gained interest in neuroimaging studies. However, it remains unclear if Big Five personality traits are represented in frequency bands (~0.25 Hz) of resting-state functional magnetic resonance imaging (fMRI) activity. Based on earlier neurophysiological studies, we investigated the correlation between the five personality traits assessed by the NEO Five-Factor Inventory (NEO-FFI), and the fractional amplitude of low-frequency fluctuation (fALFF) at four distinct frequency bands (slow-5 (0.01-0.027 Hz), slow-4 (0.027-0.073 Hz), slow-3 (0.073-0.198 Hz) and slow-2 (0.198-0.25 Hz)). We enrolled 835 young subjects and calculated the correlations of resting-state fMRI signals using a multiple regression analysis. We found a significant and consistent correlation between fALFF and the personality trait of extraversion at all frequency bands. Furthermore, significant correlations were detected in distinct brain regions for each frequency band. This finding supports the frequency-specific spatial representations of personality traits as previously suggested. In conclusion, our data highlight an association between human personality traits and fALFF at four distinct frequency bands.

  1. Effects of gap junction inhibition on contraction waves in the murine small intestine in relation to coupled oscillator theory.

    PubMed

    Parsons, Sean P; Huizinga, Jan D

    2015-02-15

    Waves of contraction in the small intestine correlate with slow waves generated by the myenteric network of interstitial cells of Cajal. Coupled oscillator theory has been used to explain steplike gradients in the frequency (frequency plateaux) of contraction waves along the length of the small intestine. Inhibition of gap junction coupling between oscillators should lead to predictable effects on these plateaux and the wave dislocation (wave drop) phenomena associated with their boundaries. It is these predictions that we wished to test. We used a novel multicamera diameter-mapping system to measure contraction along 25- to 30-cm lengths of murine small intestine. There were typically two to three plateaux per length of intestine. Dislocations could be limited to the wavefronts immediately about the terminated wave, giving the appearance of a three-pronged fork, i.e., a fork dislocation; additionally, localized decreases in velocity developed across a number of wavefronts, ending with the terminated wave, which could appear as a fork, i.e., slip dislocations. The gap junction inhibitor carbenoxolone increased the number of plateaux and dislocations and decreased contraction wave velocity. In some cases, the usual frequency gradient was reversed, with a plateau at a higher frequency than its proximal neighbor; thus fork dislocations were inverted, and the direction of propagation was reversed. Heptanol had no effect on the frequency or velocity of contractions but did reduce their amplitude. To understand intestinal motor patterns, the pacemaker network of the interstitial cells of Cajal is best evaluated as a system of coupled oscillators. Copyright © 2015 the American Physiological Society.

  2. Characteristic effects of stochastic oscillatory forcing on neural firing: analytical theory and comparison to paddlefish electroreceptor data.

    PubMed

    Bauermeister, Christoph; Schwalger, Tilo; Russell, David F; Neiman, Alexander B; Lindner, Benjamin

    2013-01-01

    Stochastic signals with pronounced oscillatory components are frequently encountered in neural systems. Input currents to a neuron in the form of stochastic oscillations could be of exogenous origin, e.g. sensory input or synaptic input from a network rhythm. They shape spike firing statistics in a characteristic way, which we explore theoretically in this report. We consider a perfect integrate-and-fire neuron that is stimulated by a constant base current (to drive regular spontaneous firing), along with Gaussian narrow-band noise (a simple example of stochastic oscillations), and a broadband noise. We derive expressions for the nth-order interval distribution, its variance, and the serial correlation coefficients of the interspike intervals (ISIs) and confirm these analytical results by computer simulations. The theory is then applied to experimental data from electroreceptors of paddlefish, which have two distinct types of internal noisy oscillators, one forcing the other. The theory provides an analytical description of their afferent spiking statistics during spontaneous firing, and replicates a pronounced dependence of ISI serial correlation coefficients on the relative frequency of the driving oscillations, and furthermore allows extraction of certain parameters of the intrinsic oscillators embedded in these electroreceptors.

  3. Generation of mechanical oscillation applicable to vibratory rate gyroscopes

    NASA Technical Reports Server (NTRS)

    Lemkin, Mark A. (Inventor); Juneau, Thor N. (Inventor); Clark, William A. (Inventor); Roessig, Allen W. (Inventor)

    2001-01-01

    To achieve a drive-axis oscillation with improved frequency and amplitude stability, additional feedback loops are used to adjust force-feedback loop parameters. An amplitude-control loop measures oscillation amplitude, compares this value to the desired level, and adjusts damping of the mechanical sense-element to grow or shrink oscillation amplitude as appropriate. A frequency-tuning loop measures the oscillation frequency, compares this value with a highly stable reference, and adjusts the gain in the force-feedback loop to keep the drive-axis oscillation frequency at the reference value. The combined topology simultaneously controls both amplitude and frequency. Advantages of the combined topology include improved stability, fast oscillation start-up, low power consumption, and excellent shock rejection.

  4. Frequency stability improvement for piezoresistive micromechanical oscillators via synchronization

    NASA Astrophysics Data System (ADS)

    Pu, Dong; Huan, Ronghua; Wei, Xueyong

    2017-03-01

    Synchronization phenomenon first discovered in Huygens' clock shows that the rhythms of oscillating objects can be adjusted via an interaction. Here we show that the frequency stability of a piezoresistive micromechanical oscillator can be enhanced via synchronization. The micromechanical clamped-clamped beam oscillator is built up using the electrostatic driving and piezoresistive sensing technique and the synchronization phenomenon is observed after coupling it to an external oscillator. An enhancement of frequency stability is obtained in the synchronization state. The influences of the synchronizing perturbation intensity and frequency detuning applied on the oscillator are studied experimentally. A theoretical analysis of phase noise leads to an analytical formula for predicting Allan deviation of the frequency output of the piezoresistive oscillator, which successfully explains the experimental observations and the mechanism of frequency stability enhancement via synchronization.

  5. Covariability of seasonal temperature and precipitation over the Iberian Peninsula in high-resolution regional climate simulations (1001-2099)

    NASA Astrophysics Data System (ADS)

    Fernández-Montes, S.; Gómez-Navarro, J. J.; Rodrigo, F. S.; García-Valero, J. A.; Montávez, J. P.

    2017-04-01

    Precipitation and surface temperature are interdependent variables, both as a response to atmospheric dynamics and due to intrinsic thermodynamic relationships and feedbacks between them. This study analyzes the covariability of seasonal temperature (T) and precipitation (P) across the Iberian Peninsula (IP) using regional climate paleosimulations for the period 1001-1990, driven by reconstructions of external forcings. Future climate (1990-2099) was simulated according to SRES scenarios A2 and B2. These simulations enable exploring, at high spatial resolution, robust and physically consistent relationships. In winter, positive P-T correlations dominate west-central IP (Pearson correlation coefficient ρ = + 0.43, for 1001-1990), due to prevalent cold-dry and warm-wet conditions, while this relationship weakens and become negative towards mountainous, northern and eastern regions. In autumn, negative correlations appear in similar regions as in winter, whereas for summer they extend also to the N/NW of the IP. In spring, the whole IP depicts significant negative correlations, strongest for eastern regions (ρ = - 0.51). This is due to prevalent frequency of warm-dry and cold-wet modes in these regions and seasons. At the temporal scale, regional correlation series between seasonal anomalies of temperature and precipitation (assessed in 31 years running windows in 1001-1990) show very large multidecadal variability. For winter and spring, periodicities of about 50-60 years arise. The frequency of warm-dry and cold-wet modes appears correlated with the North Atlantic Oscillation (NAO), explaining mainly co-variability changes in spring. For winter and some regions in autumn, maximum and minimum P-T correlations appear in periods with enhanced meridional or easterly circulation (low or high pressure anomalies in the Mediterranean and Europe). In spring and summer, the Atlantic Multidecadal Oscillation shows some fingerprint on the frequency of warm/cold modes. For future scenarios, an intensification of the negative P-T relationship is generally found, as a result of an increased frequency of the warm-dry mode.

  6. Spherical Pendulum Small Oscillations for Slewing Crane Motion

    PubMed Central

    Perig, Alexander V.; Stadnik, Alexander N.; Deriglazov, Alexander I.

    2014-01-01

    The present paper focuses on the Lagrange mechanics-based description of small oscillations of a spherical pendulum with a uniformly rotating suspension center. The analytical solution of the natural frequencies' problem has been derived for the case of uniform rotation of a crane boom. The payload paths have been found in the inertial reference frame fixed on earth and in the noninertial reference frame, which is connected with the rotating crane boom. The numerical amplitude-frequency characteristics of the relative payload motion have been found. The mechanical interpretation of the terms in Lagrange equations has been outlined. The analytical expression and numerical estimation for cable tension force have been proposed. The numerical computational results, which correlate very accurately with the experimental observations, have been shown. PMID:24526891

  7. Chaos in a chemical system

    NASA Astrophysics Data System (ADS)

    Srivastava, R.; Srivastava, P. K.; Chattopadhyay, J.

    2013-07-01

    Chaotic oscillations have been observed experimentally in dual-frequency oscillator OAP - Ce+4-BrO- 3-H2SO4 in CSTR. The system shows variation of oscillating potential and frequencies when it moves from low frequency to high frequency region and vice-versa. It was observed that system bifurcate from low frequency to chaotic regime through periode-2 and period-3 on the other hand system bifurcate from chaotic regime to high frequency oscillation through period-2. It was established that the observed oscillations are chaotic in nature on the basis of next amplitude map and bifurcation sequences.

  8. Alpha oscillations in the pedunculopontine nucleus correlate with gait performance in parkinsonism

    PubMed Central

    Thevathasan, Wesley; Pogosyan, Alek; Hyam, Jonathan A.; Jenkinson, Ned; Foltynie, Tom; Limousin, Patricia; Bogdanovic, Marko; Zrinzo, Ludvic; Green, Alexander L.; Aziz, Tipu Z.

    2012-01-01

    The pedunculopontine nucleus, a component of the reticular formation, is topographically organized in animal models and implicated in locomotor control. In Parkinson's disease, pedunculopontine nucleus stimulation is an emerging treatment for gait freezing. Local field potentials recorded from pedunculopontine nucleus electrodes in such patients have demonstrated oscillations in the alpha and beta frequency bands, reactive to self-paced movement. Whether these oscillations are topographically organized or relevant to locomotion is unknown. Here, we recorded local field potentials from the pedunculopontine nucleus in parkinsonian patients during rest and unconstrained walking. Relative gait speed was assessed with trunk accelerometry. Peaks of alpha power were present at rest and during gait, when they correlated with gait speed. Gait freezing was associated with attenuation of alpha activity. Beta peaks were less consistently observed across rest and gait, and did not correlate with gait speed. Alpha power was maximal in the caudal pedunculopontine nucleus region and beta power was maximal rostrally. These results indicate a topographic distribution of neuronal activity in the pedunculopontine nucleus region and concur with animal data suggesting that the caudal subregion has particular relevance to gait. Alpha synchronization, proposed to suppress ‘task irrelevant’ distraction, has previously been demonstrated to correlate with performance of cognitive tasks. Here, we demonstrate a correlation between alpha oscillations and improved gait performance. The results raise the possibility that stimulation of caudal and rostral pedunculopontine nucleus regions may differ in their clinical effects. PMID:22232591

  9. Flood frequencies and durations and their response to El Niño Southern Oscillation: Global analysis

    NASA Astrophysics Data System (ADS)

    Ward, P. J.; Kummu, M.; Lall, U.

    2016-08-01

    Floods are one of the most serious forms of natural hazards in terms of the damages they cause. In 2012 alone, flood damages exceeded 19 billion. A large proportion of the damages from several recent major flood disasters, such as those in South India and South Carolina (2015), England and Wales (2014), the Mississippi (2012), Thailand (2011), Queensland (Australia) (2010-2011), and Pakistan (2010), were related to the long duration of those flood events. However, most flood risk studies to date do not account for flood duration. In this paper, we provide the first global modelling exercise to assess the link between interannual climate variability and flood duration and frequency. Specifically, we examine relationships between simulated flood events and El Niño Southern Oscillation (ENSO). Our results show that the duration of flooding appears to be more sensitive to ENSO than is the case for flood frequency. At the globally aggregated scale, we found floods to be significantly longer during both El Niño and La Niña years, compared to neutral years. At the scale of individual river basins, we found strong correlations between ENSO and both flood frequency and duration for a large number of basins, with generally stronger correlations for flood duration than for flood frequency. Future research on flood impacts should attempt to incorporate more information on flood durations.

  10. Synchronous Oscillations in Van Der Pol Generator with Modulated Natural Frequency

    NASA Astrophysics Data System (ADS)

    Nimets, A. Yu.; Vavriv, D. M.

    2015-12-01

    The synchronous operation of Van Der Pole generator with the low-frequency modulated natural frequency has been investigated. The presence of low-frequency modulation is shown to lead to formation of additional synchronization regions. The appearance of such regions is found to be caused by threefrequency resonances resulted from the interaction between oscillations of the generator natural frequency, modulation frequency and synchronized signal frequency. Characteristics of synchronous oscillations due to the below mentioned three-frequency interaction are obtained and comparison with the case of synchronization of oscillator on the main mode made.

  11. Inter-annual and decadal changes in teleconnections drive continental-scale synchronization of tree reproduction.

    PubMed

    Ascoli, Davide; Vacchiano, Giorgio; Turco, Marco; Conedera, Marco; Drobyshev, Igor; Maringer, Janet; Motta, Renzo; Hacket-Pain, Andrew

    2017-12-20

    Climate teleconnections drive highly variable and synchronous seed production (masting) over large scales. Disentangling the effect of high-frequency (inter-annual variation) from low-frequency (decadal trends) components of climate oscillations will improve our understanding of masting as an ecosystem process. Using century-long observations on masting (the MASTREE database) and data on the Northern Atlantic Oscillation (NAO), we show that in the last 60 years both high-frequency summer and spring NAO, and low-frequency winter NAO components are highly correlated to continent-wide masting in European beech and Norway spruce. Relationships are weaker (non-stationary) in the early twentieth century. This finding improves our understanding on how climate variation affects large-scale synchronization of tree masting. Moreover, it supports the connection between proximate and ultimate causes of masting: indeed, large-scale features of atmospheric circulation coherently drive cues and resources for masting, as well as its evolutionary drivers, such as pollination efficiency, abundance of seed dispersers, and natural disturbance regimes.

  12. Identified Cellular Correlates of Neocortical Ripple and High-Gamma Oscillations during Spindles of Natural Sleep.

    PubMed

    Averkin, Robert G; Szemenyei, Viktor; Bordé, Sándor; Tamás, Gábor

    2016-11-23

    Ultra-high-frequency network events in the hippocampus are instrumental in a dialogue with the neocortex during memory formation, but the existence of transient ∼200 Hz network events in the neocortex is not clear. Our recordings from neocortical layer II/III of freely behaving rats revealed field potential events at ripple and high-gamma frequencies repeatedly occurring at troughs of spindle oscillations during sleep. Juxtacellular recordings identified subpopulations of fast-spiking, parvalbumin-containing basket cells with epochs of firing at ripple (∼200 Hz) and high-gamma (∼120 Hz) frequencies detected during spindles and centered with millisecond precision at the trough of spindle waves in phase with field potential events but phase shifted relative to pyramidal cell firing. The results suggest that basket cell subpopulations are involved in spindle-nested, high-frequency network events that hypothetically provide repeatedly occurring neocortical temporal reference states potentially involved in mnemonic processes. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  13. Human Genomic Signatures of Brain Oscillations During Memory Encoding.

    PubMed

    Berto, Stefano; Wang, Guang-Zhong; Germi, James; Lega, Bradley C; Konopka, Genevieve

    2018-05-01

    Memory encoding is an essential step for all learning. However, the genetic and molecular mechanisms underlying human memory encoding remain poorly understood, and how this molecular framework permits the emergence of specific patterns of brain oscillations observed during mnemonic processing is unknown. Here, we directly compare intracranial electroencephalography recordings from the neocortex in individuals performing an episodic memory task with human gene expression from the same areas. We identify genes correlated with oscillatory memory effects across 6 frequency bands. These genes are enriched for autism-related genes and have preferential expression in neurons, in particular genes encoding synaptic proteins and ion channels, supporting the idea that the genes regulating voltage gradients are involved in the modulation of oscillatory patterns during successful memory encoding across brain areas. Memory-related genes are distinct from those correlated with other forms of cognitive processing and resting state fMRI. These data are the first to identify correlations between gene expression and active human brain states as well as provide a molecular window into memory encoding oscillations in the human brain.

  14. Trains of electrical stimulation of the trapezius muscles redistribute the frequencies of body oscillations during stance.

    PubMed

    Nhouvannasak, V; Clément, S; Manto, M

    2015-09-01

    We investigated the postural effects of trains of electrical stimulation (TES) applied unilaterally or bilaterally on the trapezius muscle in 20 healthy subjects (mean age: 23.1 ± 1.33 years; F/M: 8/12). The anterior-posterior (AP) displacements (AP axis), medio-lateral displacements (ML axis) and total travelled distances (TTW) of the centre of pressure (COP) remained unchanged with TES. However, detailed spectral analysis of COP oscillations revealed a marked decrease of the magnitudes of peak power spectral density (peak PSD) following application of TES. Peak PSD was highly correlated with the intensity of stimulation (P < 0.001 both the AP and ML axes). For the AP axis, the integrals of the sub-bands 0-0.4, 0.4-1.5, 1.5-3 Hz were significantly decreased (P < 0.001), the integrals of the sub-bands 3-5 and 5-8 Hz were not significantly affected (P>0.30) and the integrals of the sub-band 8-10 Hz were significantly increased (P < 0.001). The ratios of the integrals of sub-bands 8-10 Hz/0-3 Hz were markedly enhanced with bilateral TES (P < 0.001). For the ML axis, the effects were striking (P < 0.001) for the sub-bands 0-0.4, 0.4-1.5 and 8-10 Hz. For both the AP and ML axes, a significant inverse linear relationship was found between the intensity of TES and the average speed of COP. We show that TES applied over the trapezius muscles exerts significant and so far unrecognised effects upon oscillations of the COP, decreasing low-frequency oscillations and enhancing high-frequency oscillations. Our data unravel a novel property of the trapezius muscles upon postural control. We suggest that this muscle plays a role of a distributor of low-frequency versus high-frequency sub-bands of frequency during stance. Previous studies have shown that patients with supra-tentorial stroke show an increased peak PSD in low frequencies of body oscillations. Therefore, our findings provide a rationale to assess neurostimulation of the trapezius muscle in the rehabilitation of postural deficits in supra-tentorial stroke.

  15. Nonlinear dynamics of the human lumbar intervertebral disc.

    PubMed

    Marini, Giacomo; Huber, Gerd; Püschel, Klaus; Ferguson, Stephen J

    2015-02-05

    Systems with a quasi-static response similar to the axial response of the intervertebral disc (i.e. progressive stiffening) often present complex dynamics, characterized by peculiar nonlinearities in the frequency response. However, such characteristics have not been reported for the dynamic response of the disc. The accurate understanding of disc dynamics is essential to investigate the unclear correlation between whole body vibration and low back pain. The present study investigated the dynamic response of the disc, including its potential nonlinear response, over a range of loading conditions. Human lumbar discs were tested by applying a static preload to the top and a sinusoidal displacement at the bottom of the disc. The frequency of the stimuli was set to increase linearly from a low frequency to a high frequency limit and back down. In general, the response showed nonlinear and asymmetric characteristics. For each test, the disc had different response in the frequency-increasing compared to the frequency-decreasing sweep. In particular, the system presented abrupt changes of the oscillation amplitude at specific frequencies, which differed between the two sweeps. This behaviour indicates that the system oscillation has a different equilibrium condition depending on the path followed by the stimuli. Preload and amplitude of the oscillation directly influenced the disc response by changing the nonlinear dynamics and frequency of the jump-phenomenon. These results show that the characterization of the dynamic response of physiological systems should be readdressed to determine potential nonlinearities. Their direct effect on the system function should be further investigated. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiang, Z.; Lawson, B.; Asaba, T.

    The Kondo insulator samarium hexaboride (SmB 6) has been intensely studied in recent years as a potential candidate of a strongly correlated topological insulator. One of the most exciting phenomena observed in SmB 6 is the clear quantum oscillations appearing in magnetic torque at a low temperature despite the insulating behavior in resistance. These quantum oscillations show multiple frequencies and varied effective masses. The origin of quantum oscillation is, however, still under debate with evidence of both two-dimensional Fermi surfaces and three-dimensional Fermi surfaces. Here, we carry out angle-resolved torque magnetometry measurements in a magnetic field up to 45 Tmore » and a temperature range down to 40 mK. With the magnetic field rotated in the (010) plane, the quantum oscillation frequency of the strongest oscillation branch shows a fourfold rotational symmetry. However, in the angular dependence of the amplitude of the same branch, this fourfold symmetry is broken and, instead, a twofold symmetry shows up, which is consistent with the prediction of a two-dimensional Lifshitz-Kosevich model. No deviation of Lifshitz-Kosevich behavior is observed down to 40 mK. Our results suggest the existence of multiple light-mass surface states in SmB 6, with their mobility significantly depending on the surface disorder level.« less

  17. Bulk Rotational Symmetry Breaking in Kondo Insulator SmB 6

    DOE PAGES

    Xiang, Z.; Lawson, B.; Asaba, T.; ...

    2017-09-25

    The Kondo insulator samarium hexaboride (SmB 6) has been intensely studied in recent years as a potential candidate of a strongly correlated topological insulator. One of the most exciting phenomena observed in SmB 6 is the clear quantum oscillations appearing in magnetic torque at a low temperature despite the insulating behavior in resistance. These quantum oscillations show multiple frequencies and varied effective masses. The origin of quantum oscillation is, however, still under debate with evidence of both two-dimensional Fermi surfaces and three-dimensional Fermi surfaces. Here, we carry out angle-resolved torque magnetometry measurements in a magnetic field up to 45 Tmore » and a temperature range down to 40 mK. With the magnetic field rotated in the (010) plane, the quantum oscillation frequency of the strongest oscillation branch shows a fourfold rotational symmetry. However, in the angular dependence of the amplitude of the same branch, this fourfold symmetry is broken and, instead, a twofold symmetry shows up, which is consistent with the prediction of a two-dimensional Lifshitz-Kosevich model. No deviation of Lifshitz-Kosevich behavior is observed down to 40 mK. Our results suggest the existence of multiple light-mass surface states in SmB 6, with their mobility significantly depending on the surface disorder level.« less

  18. Traveling Theta Waves in the Human Hippocampus

    PubMed Central

    Zhang, Honghui

    2015-01-01

    The hippocampal theta oscillation is strongly correlated with behaviors such as memory and spatial navigation, but we do not understand its specific functional role. One hint of theta's function came from the discovery in rodents that theta oscillations are traveling waves that allow parts of the hippocampus to simultaneously exhibit separate oscillatory phases. Because hippocampal theta oscillations in humans have different properties compared with rodents, we examined these signals directly using multielectrode recordings from neurosurgical patients. Our findings confirm that human hippocampal theta oscillations are traveling waves, but also show that these oscillations appear at a broader range of frequencies compared with rodents. Human traveling waves showed a distinctive pattern of spatial propagation such that there is a consistent phase spread across the hippocampus regardless of the oscillations' frequency. This suggests that traveling theta oscillations are important functionally in humans because they coordinate phase coding throughout the hippocampus in a consistent manner. SIGNIFICANCE STATEMENT We show for the first time in humans that hippocampal theta oscillations are traveling waves, moving along the length of the hippocampus in a posterior–anterior direction. The existence of these traveling theta waves is important for understanding hippocampal neural coding because they cause neurons at separate positions in the hippocampus to experience different theta phases simultaneously. The theta phase that a neuron measures is a key factor in how that cell represents behavioral information. Therefore, the existence of traveling theta waves indicates that, to fully understand how a hippocampal neuron represents information, it is vital to also account for that cell's location in addition to conventional measures of neural activity. PMID:26354915

  19. Quantum correlations across two octaves from combined up- and down-conversion

    NASA Astrophysics Data System (ADS)

    Li, Jingyan; Olsen, M. K.

    2018-04-01

    We propose and analyze a cascaded optical parametric system which involves three interacting modes across two octaves of frequency difference. Our system, combining degenerate optical parametric oscillation (OPO) with second harmonic generation (SHG), promises to be a useful source of squeezed and entangled light at three differing frequencies. We show how changes in damping rates and the ratio of the two concurrent nonlinearities affect the quantum correlations in the output fields. We analyze the threshold behavior, showing how the normal OPO threshold is changed by the addition of the SHG interactions. We also find that the inclusion of the OPO interaction removes the self-pulsing behavior found in normal SHG. Finally, we show how the Einstein-Podolsky-Rosen correlations can be controlled by the injection of a coherent seed field at the lower frequency.

  20. Synchronization of electrically coupled micromechanical oscillators with a frequency ratio of 3:1

    NASA Astrophysics Data System (ADS)

    Pu, Dong; Wei, Xueyong; Xu, Liu; Jiang, Zhuangde; Huan, Ronghua

    2018-01-01

    In this Letter, synchronization of micromechanical oscillators with a frequency ratio of 3:1 is reported. Two electrically coupled piezoresistive micromechanical oscillators are built for the study, and their oscillation frequencies are tuned via the Joule heating effect to find out the synchronization region. Experimental results show that the larger coupling strength or bias driving voltage is applied and a wider synchronization region is obtained. Interestingly, however, the oscillator's frequency tunability is dramatically reduced from -809.1 Hz/V to -23.1 Hz/V when synchronization is reached. A nearly 10-fold improvement of frequency stability at 1 s is observed from one of the synchronized oscillators, showing a comparable performance of the other. The stable high order synchronization of micromechanical oscillators is helpful to design high performance resonant sensors with a better frequency resolution and a larger scale factor.

  1. Low-Frequency Oscillations and Control of the Motor Output

    PubMed Central

    Lodha, Neha; Christou, Evangelos A.

    2017-01-01

    A less precise force output impairs our ability to perform movements, learn new motor tasks, and use tools. Here we show that low-frequency oscillations in force are detrimental to force precision. We summarize the recent evidence that low-frequency oscillations in force output represent oscillations of the spinal motor neuron pool from the voluntary drive, and can be modulated by shifting power to higher frequencies. Further, force oscillations below 0.5 Hz impair force precision with increased voluntary drive, aging, and neurological disease. We argue that the low-frequency oscillations are (1) embedded in the descending drive as shown by the activation of multiple spinal motor neurons, (2) are altered with force intensity and brain pathology, and (3) can be modulated by visual feedback and motor training to enhance force precision. Thus, low-frequency oscillations in force provide insight into how the human brain regulates force precision. PMID:28261107

  2. Elastic constant and Brillouin oscillations in sputtered vitreous SiO2 thin films

    NASA Astrophysics Data System (ADS)

    Ogi, H.; Shagawa, T.; Nakamura, N.; Hirao, M.; Odaka, H.; Kihara, N.

    2008-10-01

    We studied the relationship between elastic constants and microstructure in sputtered vitreous SiO2 thin films using pump-probe picosecond laser ultrasound. The delayed probe light pulse is diffracted by the acoustic wave excited by the pump light pulse, inducing Brillouin oscillations, seen as reflectivity change in the probe pulse, whose frequency can be used to extract the sound velocity and elastic moduli. Theoretical calculations were made to explain the asymmetric response of Brillouin oscillations and to predict the possible error limit of the determined elastic constants. The thin films containing defects exhibited lower elastic constant. A micromechanics modeling was developed to evaluate defect porosity and attenuation caused by scattering was able to predict the defect size. Elastic moduli of the defect-free specimens increased with increasing sputtering power, eventually exceeding the bulk value, and correlated with phonon frequencies, indicating that the decrease in the Si-O-Si bond angle of the tetrahedral structure increased the stiffness.

  3. METHOD FOR STABILIZING KLYSTRONS

    DOEpatents

    Magnuson, D.W.; Smith, D.F.

    1959-04-14

    High-frequency oscillators for the generation of microwaves, particularly a system for stabilizing frequency-modulated klystron oscillators of the reflex type, are described. The system takos advantage of the fact that a change in oscillator frequency will alter the normal phase displacement between the cavity and its modulator, creating an error voltage which is utilized to regulate the frequency of the oscillator and stabilize it.

  4. Characterization of Low-Frequency Combustion Stability of the Fastrac Engine

    NASA Technical Reports Server (NTRS)

    Rocker, Marvin; Jones, Preston (Technical Monitor)

    2002-01-01

    A series of tests were conducted to measure the combustion performance of the Fastrac engine thrust chamber. During mainstage, the thrust chamber exhibited no large-amplitude chamber pressure oscillations that could be identified as low-frequency combustion instability or 'chug'. However, during start-up and shutdown, the thrust chamber very briefly exhibited large-amplitude chamber pressure oscillations that were identified as chug. These instabilities during start-up and shutdown were regarded as benign due to their brevity. Linear models of the thrust chamber and the propellant feed systems were formulated for both the thrust chamber component tests and the flight engine tests. These linear models determined the frequency and decay rate of chamber pressure oscillations given the design and operating conditions of the thrust chamber and feed system. The frequency of chamber pressure oscillations determined from the model closely matched the frequency of low-amplitude, low-frequency chamber pressure oscillations exhibited in some of the later thrust chamber mainstage tests. The decay rate of the chamber pressure oscillations determined from the models indicated that these low-frequency oscillations were stable. Likewise, the decay rate, determined from the model of the flight engine tests indicated that the low-frequency chamber pressure oscillations would be stable.

  5. Improved Tracking of an Atomic-Clock Resonance Transition

    NASA Technical Reports Server (NTRS)

    Prestage, John D.; Chung, Sang K.; Tu, Meirong

    2010-01-01

    An improved method of making an electronic oscillator track the frequency of an atomic-clock resonance transition is based on fitting a theoretical nonlinear curve to measurements at three oscillator frequencies within the operational frequency band of the transition (in other words, at three points within the resonance peak). In the measurement process, the frequency of a microwave oscillator is repeatedly set at various offsets from the nominal resonance frequency, the oscillator signal is applied in a square pulse of the oscillator signal having a suitable duration (typically, of the order of a second), and, for each pulse at each frequency offset, fluorescence photons of the transition in question are counted. As described below, the counts are used to determine a new nominal resonance frequency. Thereafter, offsets are determined with respect to the new resonance frequency. The process as described thus far is repeated so as to repeatedly adjust the oscillator to track the most recent estimate of the nominal resonance frequency.

  6. Recent progress in opto-electronic oscillator

    NASA Technical Reports Server (NTRS)

    Maleki, Lute

    2005-01-01

    The optoelectronic oscillator (OEO) is a unique device based on photonics techniques to generate highly spectrally pure microwave signals [1]. The development of the OEO was motivated by the need for high performance oscillators in the frequency range larger than 10 GHz, where conventional electronic oscillators have a number of limitations. These limitations typically stem from the product of fQ, where f is the oscillator frequency and Q is the quality factor of the resonator in the oscillator. In conventional resonators, whether electromagnetic or piezoelectric, this product is usually a constant. Thus, as the oscillator frequency is pushed higher, the quality factor degrades, resulting in degradation of the phase noise of the oscillator. An approach to mitigate the problem is to start with a very high quality signal in the 5 to 100 MHz range generated by a quartz oscillator and multiply the frequency to achieve the desired microwave signal. Here again, frequency multiplication also results in an increase of the phase noise by a factor of 2010gN, where N is the multiplication factor.

  7. Initial high-degree p-mode frequency splittings from the 1988 Mt. Wilson 60-foot Tower Solar Oscillation Program

    NASA Technical Reports Server (NTRS)

    Rhodes, Edward J., Jr.; Cacciani, Alessandro; Korzennik, Sylvain G.

    1988-01-01

    The initial frequency splitting results of solar p-mode oscillations obtained from the 1988 helioseismology program at the Mt. Wilson Observatory are presented. The frequency splittings correspond to the rotational splittings of sectoral harmonics which range in degree between 10 and 598. They were obtained from a cross-correlation analysis of the prograde and retrograde portions of a two-dimensional (t - v) power spectrum. This power spectrum was computed from an eight-hour sequence of full-disk Dopplergrams obtained on July 2, 1988, at the 60-foot tower telescope with a Na magneto-optical filter and a 1024x1024 pixel CCD camera. These frequency splittings have an inherently larger scatter than did the splittings obtained from earlier 16-day power spectra. These splittings are consistent with an internal solar rotational velocity which is independent of radius along the equatorial plane. The normalized frequency splittings averaged 449 + or - 3 nHz, a value which is very close to the observed equatorial rotation rate of the photospheric gas of 451.7 nHz.

  8. Neuronal Oscillations with Non-sinusoidal Morphology Produce Spurious Phase-to-Amplitude Coupling and Directionality

    PubMed Central

    Lozano-Soldevilla, Diego; ter Huurne, Niels; Oostenveld, Robert

    2016-01-01

    Neuronal oscillations support cognitive processing. Modern views suggest that neuronal oscillations do not only reflect coordinated activity in spatially distributed networks, but also that there is interaction between the oscillations at different frequencies. For example, invasive recordings in animals and humans have found that the amplitude of fast oscillations (>40 Hz) occur non-uniformly within the phase of slower oscillations, forming the so-called cross-frequency coupling (CFC). However, the CFC patterns might be influenced by features in the signal that do not relate to underlying physiological interactions. For example, CFC estimates may be sensitive to spectral correlations due to non-sinusoidal properties of the alpha band wave morphology. To investigate this issue, we performed CFC analysis using experimental and synthetic data. The former consisted in a double-blind magnetoencephalography pharmacological study in which participants received either placebo, 0.5 or 1.5 mg of lorazepam (LZP; GABAergic enhancer) in different experimental sessions. By recording oscillatory brain activity with during rest and working memory (WM), we were able to demonstrate that posterior alpha (8–12 Hz) phase was coupled to beta-low gamma band (20–45 Hz) amplitude envelope during all sessions. Importantly, bicoherence values around the harmonics of the alpha frequency were similar both in magnitude and topographic distribution to the cross-frequency coherence (CFCoh) values observed in the alpha-phase to beta-low gamma coupling. In addition, despite the large CFCoh we found no significant cross-frequency directionality (CFD). Critically, simulations demonstrated that a sizable part of our empirical CFCoh between alpha and beta-low gamma coupling and the lack of CFD could be explained by two-three harmonics aligned in zero phase-lag produced by the physiologically characteristic alpha asymmetry in the amplitude of the peaks relative to the troughs. Furthermore, we showed that periodic signals whose waveform deviate from pure sine waves produce non-zero CFCoh with predictable CFD. Our results reveal the important role of the non-sinusoidal wave morphology on state of the art CFC metrics and we recommend caution with strong physiological interpretations of CFC and suggest basic data quality checks to enhance the mechanistic understanding of CFC. PMID:27597822

  9. Frequency-locked chaotic opto-RF oscillator.

    PubMed

    Thorette, Aurélien; Romanelli, Marco; Brunel, Marc; Vallet, Marc

    2016-06-15

    A driven opto-RF oscillator, consisting of a dual-frequency laser (DFL) submitted to frequency-shifted feedback, is experimentally and numerically studied in a chaotic regime. Precise control of the reinjection strength and detuning permits isolation of a parameter region of bounded-phase chaos, where the opto-RF oscillator is frequency-locked to the master oscillator, in spite of chaotic phase and intensity oscillations. Robust experimental evidence of this synchronization regime is found, and phase noise spectra allow us to compare phase-locking and bounded-phase chaos regimes. In particular, it is found that the long-term phase stability of the master oscillator is well transferred to the opto-RF oscillator, even in the chaotic regime.

  10. Quantum-correlated two-photon transitions to excitons in semiconductor quantum wells.

    PubMed

    Salazar, L J; Guzmán, D A; Rodríguez, F J; Quiroga, L

    2012-02-13

    The dependence of the excitonic two-photon absorption on the quantum correlations (entanglement) of exciting biphotons by a semiconductor quantum well is studied. We show that entangled photon absorption can display very unusual features depending on space-time-polarization biphoton parameters and absorber density of states for both bound exciton states as well as for unbound electron-hole pairs. We report on the connection between biphoton entanglement, as quantified by the Schmidt number, and absorption by a semiconductor quantum well. Comparison between frequency-anti-correlated, unentangled and frequency-correlated biphoton absorption is addressed. We found that exciton oscillator strengths are highly increased when photons arrive almost simultaneously in an entangled state. Two-photon-absorption becomes a highly sensitive probe of photon quantum correlations when narrow semiconductor quantum wells are used as two-photon absorbers.

  11. Solution to the indexing problem of frequency domain simulation experiments

    NASA Technical Reports Server (NTRS)

    Mitra, Mousumi; Park, Stephen K.

    1991-01-01

    A frequency domain simulation experiment is one in which selected system parameters are oscillated sinusoidally to induce oscillations in one or more system statistics of interest. A spectral (Fourier) analysis of these induced oscillations is then performed. To perform this spectral analysis, all oscillation frequencies must be referenced to a common, independent variable - an oscillation index. In a discrete-event simulation, the global simulation clock is the most natural choice for the oscillation index. However, past efforts to reference all frequencies to the simulation clock generally yielded unsatisfactory results. The reason for these unsatisfactory results is explained in this paper and a new methodology which uses the simulation clock as the oscillation index is presented. Techniques for implementing this new methodology are demonstrated by performing a frequency domain simulation experiment for a network of queues.

  12. Frequency spectrum analyzer with phase-lock

    DOEpatents

    Boland, Thomas J.

    1984-01-01

    A frequency-spectrum analyzer with phase-lock for analyzing the frequency and amplitude of an input signal is comprised of a voltage controlled oscillator (VCO) which is driven by a ramp generator, and a phase error detector circuit. The phase error detector circuit measures the difference in phase between the VCO and the input signal, and drives the VCO locking it in phase momentarily with the input signal. The input signal and the output of the VCO are fed into a correlator which transfers the input signal to a frequency domain, while providing an accurate absolute amplitude measurement of each frequency component of the input signal.

  13. Intermittent stick-slip dynamics during the peeling of an adhesive tape from a roller.

    PubMed

    Cortet, Pierre-Philippe; Dalbe, Marie-Julie; Guerra, Claudia; Cohen, Caroline; Ciccotti, Matteo; Santucci, Stéphane; Vanel, Loïc

    2013-02-01

    We study experimentally the fracture dynamics during the peeling at a constant velocity of a roller adhesive tape mounted on a freely rotating pulley. Thanks to a high speed camera, we measure, in an intermediate range of peeling velocities, high frequency oscillations between phases of slow and rapid propagation of the peeling fracture. This so-called stick-slip regime is well known as the consequence of a decreasing fracture energy of the adhesive in a certain range of peeling velocity coupled to the elasticity of the peeled tape. Simultaneously with stick slip, we observe low frequency oscillations of the adhesive roller angular velocity which are the consequence of a pendular instability of the roller submitted to the peeling force. The stick-slip dynamics is shown to become intermittent due to these slow pendular oscillations which produce a quasistatic oscillation of the peeling angle while keeping constant the peeling fracture velocity (averaged over each stick-slip cycle). The observed correlation between the mean peeling angle and the stick-slip amplitude questions the validity of the usually admitted independence with the peeling angle of the fracture energy of adhesives.

  14. Frequency jumps in single chip microwave LC oscillators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gualco, Gabriele; Grisi, Marco; Boero, Giovanni, E-mail: giovanni.boero@epfl.ch

    2014-12-15

    We report on the experimental observation of oscillation frequency jumps in microwave LC oscillators fabricated using standard complementary metal-oxide-semiconductor technologies. The LC oscillators, operating at a frequency of about 20 GHz, consist of a single turn planar coil, a metal-oxide-metal capacitor, and two cross-coupled metal-oxide-semiconductor field effect transistors used as negative resistance network. At 300 K as well as at 77 K, the oscillation frequency is a continuous function of the oscillator bias voltage. At 4 K, frequency jumps as large as 30 MHz are experimentally observed. This behavior is tentatively attributed to the emission and capture of single electrons from defects andmore » dopant atoms.« less

  15. Phase reduction of a limit cycle oscillator perturbed by a strong amplitude-modulated high-frequency force.

    PubMed

    Pyragas, Kestutis; Novičenko, Viktor

    2015-07-01

    The phase reduction method for a limit cycle oscillator subjected to a strong amplitude-modulated high-frequency force is developed. An equation for the phase dynamics is derived by introducing a new, effective phase response curve. We show that if the effective phase response curve is everywhere positive (negative), then an entrainment of the oscillator to an envelope frequency is possible only when this frequency is higher (lower) than the natural frequency of the oscillator. Also, by using the Pontryagin maximum principle, we have derived an optimal waveform of the perturbation that ensures an entrainment of the oscillator with minimal power. The theoretical results are demonstrated with the Stuart-Landau oscillator and model neurons.

  16. Membrane Resonance Enables Stable and Robust Gamma Oscillations

    PubMed Central

    Moca, Vasile V.; Nikolić, Danko; Singer, Wolf; Mureşan, Raul C.

    2014-01-01

    Neuronal mechanisms underlying beta/gamma oscillations (20–80 Hz) are not completely understood. Here, we show that in vivo beta/gamma oscillations in the cat visual cortex sometimes exhibit remarkably stable frequency even when inputs fluctuate dramatically. Enhanced frequency stability is associated with stronger oscillations measured in individual units and larger power in the local field potential. Simulations of neuronal circuitry demonstrate that membrane properties of inhibitory interneurons strongly determine the characteristics of emergent oscillations. Exploration of networks containing either integrator or resonator inhibitory interneurons revealed that: (i) Resonance, as opposed to integration, promotes robust oscillations with large power and stable frequency via a mechanism called RING (Resonance INduced Gamma); resonance favors synchronization by reducing phase delays between interneurons and imposes bounds on oscillation cycle duration; (ii) Stability of frequency and robustness of the oscillation also depend on the relative timing of excitatory and inhibitory volleys within the oscillation cycle; (iii) RING can reproduce characteristics of both Pyramidal INterneuron Gamma (PING) and INterneuron Gamma (ING), transcending such classifications; (iv) In RING, robust gamma oscillations are promoted by slow but are impaired by fast inputs. Results suggest that interneuronal membrane resonance can be an important ingredient for generation of robust gamma oscillations having stable frequency. PMID:23042733

  17. A theoretical and experimental investigation of the linear and nonlinear impulse responses from a magnetoplasma column

    NASA Technical Reports Server (NTRS)

    Grody, N. C.

    1973-01-01

    Linear and nonlinear responses of a magnetoplasma resulting from inhomogeneity in the background plasma density are studied. The plasma response to an impulse electric field was measured and the results are compared with the theory of an inhomogeneous cold plasma. Impulse responses were recorded for the different plasma densities, static magnetic fields, and neutral pressures and generally appeared as modulated, damped oscillations. The frequency spectra of the waveforms consisted of two separated resonance peaks. For weak excitation, the results correlate with the linear theory of a cold, inhomogeneous, cylindrical magnetoplasma. The damping mechanism is identified with that of phase mixing due to inhomogeneity in plasma density. With increasing excitation voltage, the nonlinear impulse responses display stronger damping and a small increase in the frequency of oscillation.

  18. Neuromuscular mechanisms and neural strategies in the control of time-varying muscle contractions.

    PubMed

    Erimaki, Sophia; Agapaki, Orsalia M; Christakos, Constantinos N

    2013-09-01

    The organization of the neural input to motoneurons that underlies time-varying muscle force is assumed to depend on muscle transfer characteristics and neural strategies or control modes utilizing sensory signals. We jointly addressed these interlinked, but previously studied individually and partially, issues for sinusoidal (range 0.5-5.0 Hz) force-tracking contractions of a human finger muscle. Using spectral and correlation analyses of target signal, force signal, and motor unit (MU) discharges, we studied 1) patterns of such discharges, allowing inferences on the motoneuronal input; 2) transformation of MU population activity (EMG) into quasi-sinusoidal force; and 3) relation of force oscillation to target, carrying information on the input's organization. A broad view of force control mechanisms and strategies emerged. Specifically, synchronized MU and EMG modulations, reflecting a frequency-modulated motoneuronal input, accompanied the force variations. Gain and delay drops between EMG modulation and force oscillation, critical for the appropriate organization of this input, occurred with increasing target frequency. According to our analyses, gain compensation was achieved primarily through rhythmical activation/deactivation of higher-threshold MUs and secondarily through the adaptation of the input's strength expected during tracking tasks. However, the input's timing was not adapted to delay behaviors and seemed to depend on the control modes employed. Thus, for low-frequency targets, the force oscillation was highly coherent with, but led, a target, this timing error being compatible with predictive feedforward control partly based on the target's derivatives. In contrast, the force oscillation was weakly coherent, but in phase, with high-frequency targets, suggesting control mainly based on a target's rhythm.

  19. Spectral modification of seismic waves propagating through solids exhibiting a resonance frequency: a 1-D coupled wave propagation-oscillation model

    NASA Astrophysics Data System (ADS)

    Frehner, Marcel; Schmalholz, Stefan M.; Podladchikov, Yuri

    2009-02-01

    A 1-D model is presented that couples the microscale oscillations of non-wetting fluid blobs in a partially saturated poroelastic medium with the macroscale wave propagation through the elastic skeleton. The fluid oscillations are caused by surface tension forces that act as the restoring forces driving the oscillations. The oscillations are described mathematically with the equation for a linear oscillator and the wave propagation is described with the 1-D elastic wave equation. Coupling is done using Hamilton's variational principle for continuous systems. The resulting linear system of two partial differential equations is solved numerically with explicit finite differences. Numerical simulations are used to analyse the effect of solids exhibiting internal oscillations, and consequently a resonance frequency, on seismic waves propagating through such media. The phase velocity dispersion relation shows a higher phase velocity in the high-frequency limit and a lower phase velocity in the low-frequency limit. At the resonance frequency a singularity in the dispersion relation occurs. Seismic waves can initiate oscillations of the fluid by transferring energy from solid to fluid at the resonance frequency. Due to this transfer, the spectral amplitude of the solid particle velocity decreases at the resonance frequency. After initiation, the oscillatory movement of the fluid continuously transfers energy at the resonance frequency back to the solid. Therefore, the spectral amplitude of the solid particle velocity is increased at the resonance frequency. Once initiated, fluid oscillations decrease in amplitude with increasing time. Consequently, the spectral peak of the solid particle velocity at the resonance frequency decreases with time.

  20. Quantifying the correlation between photoplethysmography and laser Doppler flowmetry microvascular low-frequency oscillations

    NASA Astrophysics Data System (ADS)

    Mizeva, Irina; Di Maria, Costanzo; Frick, Peter; Podtaev, Sergey; Allen, John

    2015-03-01

    Photoplethysmography (PPG) and laser Doppler flowmetry (LDF) are two recognized optical techniques that can track low-frequency perfusion changes in microcirculation. The aim of this study was to determine, in healthy subjects, the correlation between the techniques for specific low-frequency bands previously defined for microcirculation. Twelve healthy male subjects (age range 18 to 50 years) were studied, with PPG and LDF signals recorded for 20 min from their right and left index (PPG) and middle (LDF) fingers. Wavelet analysis comprised dividing the low-frequency integral wavelet spectrum (IWS) into five established physiological bands relating to cardiac, respiratory, myogenic, neurogenic, and endothelial activities. The correlation between PPG and LDF was quantified using wavelet correlation analysis and Spearman correlation analysis of the median IWS amplitude. The median wavelet correlation between signals (right-left side average) was 0.45 (cardiac), 0.49 (respiratory), 0.86 (myogenic), 0.91 (neurogenic), and 0.91 (endothelial). The correlation of IWS amplitude values (right-left side average) was statistically significant for the cardiac (ρ=0.64, p<0.05) and endothelial (ρ=0.62, p<0.05) bands. This pilot study has shown good correlation between PPG and LDF for specific physiological frequency bands. In particular, the results suggest that PPG has the potential to be a low-cost replacement for LDF for endothelial activity assessments.

  1. GABA level, gamma oscillation, and working memory performance in schizophrenia

    PubMed Central

    Chen, Chi-Ming A.; Stanford, Arielle D.; Mao, Xiangling; Abi-Dargham, Anissa; Shungu, Dikoma C.; Lisanby, Sarah H.; Schroeder, Charles E.; Kegeles, Lawrence S.

    2014-01-01

    A relationship between working memory impairment, disordered neuronal oscillations, and abnormal prefrontal GABA function has been hypothesized in schizophrenia; however, in vivo GABA measurements and gamma band neural synchrony have not yet been compared in schizophrenia. This case–control pilot study (N = 24) compared baseline and working memory task-induced neuronal oscillations acquired with high-density electroencephalograms (EEGs) to GABA levels measured in vivo with magnetic resonance spectroscopy. Working memory performance, baseline GABA level in the left dorsolateral prefrontal cortex (DLPFC), and measures of gamma oscillations from EEGs at baseline and during a working memory task were obtained. A major limitation of this study is a relatively small sample size for several analyses due to the integration of diverse methodologies and participant compliance. Working memory performance was significantly lower for patients than for controls. During the working memory task, patients (n = 7) had significantly lower amplitudes in gamma oscillations than controls (n = 9). However, both at rest and across working memory stages, there were significant correlations between gamma oscillation amplitude and left DLPFC GABA level. Peak gamma frequency during the encoding stage of the working memory task (n = 16) significantly correlated with GABA level and working memory performance. Despite gamma band amplitude deficits in patients across working memory stages, both baseline and working memory-induced gamma oscillations showed strong dependence on baseline GABA levels in patients and controls. These findings suggest a critical role for GABA function in gamma band oscillations, even under conditions of system and cognitive impairments as seen in schizophrenia. PMID:24749063

  2. GABA level, gamma oscillation, and working memory performance in schizophrenia.

    PubMed

    Chen, Chi-Ming A; Stanford, Arielle D; Mao, Xiangling; Abi-Dargham, Anissa; Shungu, Dikoma C; Lisanby, Sarah H; Schroeder, Charles E; Kegeles, Lawrence S

    2014-01-01

    A relationship between working memory impairment, disordered neuronal oscillations, and abnormal prefrontal GABA function has been hypothesized in schizophrenia; however, in vivo GABA measurements and gamma band neural synchrony have not yet been compared in schizophrenia. This case-control pilot study (N = 24) compared baseline and working memory task-induced neuronal oscillations acquired with high-density electroencephalograms (EEGs) to GABA levels measured in vivo with magnetic resonance spectroscopy. Working memory performance, baseline GABA level in the left dorsolateral prefrontal cortex (DLPFC), and measures of gamma oscillations from EEGs at baseline and during a working memory task were obtained. A major limitation of this study is a relatively small sample size for several analyses due to the integration of diverse methodologies and participant compliance. Working memory performance was significantly lower for patients than for controls. During the working memory task, patients (n = 7) had significantly lower amplitudes in gamma oscillations than controls (n = 9). However, both at rest and across working memory stages, there were significant correlations between gamma oscillation amplitude and left DLPFC GABA level. Peak gamma frequency during the encoding stage of the working memory task (n = 16) significantly correlated with GABA level and working memory performance. Despite gamma band amplitude deficits in patients across working memory stages, both baseline and working memory-induced gamma oscillations showed strong dependence on baseline GABA levels in patients and controls. These findings suggest a critical role for GABA function in gamma band oscillations, even under conditions of system and cognitive impairments as seen in schizophrenia.

  3. Parametric resonance in acoustically levitated water drops

    NASA Astrophysics Data System (ADS)

    Shen, C. L.; Xie, W. J.; Wei, B.

    2010-05-01

    Liquid drops can be suspended in air with acoustic levitation method. When the sound pressure is periodically modulated, the levitated drop is usually forced into an axisymmetric oscillation. However, a transition from axisymmetric oscillation into sectorial oscillation occurs when the modulation frequency approaches some specific values. The frequency of the sectorial oscillation is almost exactly half of the modulation frequency. It is demonstrated that this transition is induced by the parametric resonance of levitated drop. The natural frequency of sectorial oscillation is found to decrease with the increase of drop distortion extent.

  4. A self-contained quantum harmonic engine

    NASA Astrophysics Data System (ADS)

    Reid, B.; Pigeon, S.; Antezza, M.; De Chiara, G.

    2017-12-01

    We propose a system made of three quantum harmonic oscillators as a compact quantum engine for producing mechanical work. The three oscillators play respectively the role of the hot bath, the working medium and the cold bath. The working medium performs an Otto cycle during which its frequency is changed and it is sequentially coupled to each of the two other oscillators. As the two environments are finite, the lifetime of the machine is finite and after a number of cycles it stops working and needs to be reset. Remarkably, we show that this machine can extract more than 90% of the available energy during 70 cycles. Differently from usually investigated infinite-reservoir configurations, this machine allows the protection of induced quantum correlations and we analyse the entanglement and quantum discord generated during the strokes. Interestingly, we show that high work generation is always accompanied by large quantum correlations. Our predictions can be useful for energy management at the nanoscale, and can be relevant for experiments with trapped ions and experiments with light in integrated optical circuits.

  5. Ultrastable Cryogenic Microwave Oscillators

    NASA Astrophysics Data System (ADS)

    Mann, Anthony G.

    Ultrastable cryogenic microwave oscillators are secondary frequency standards in the microwave domain. The best of these oscillators have demonstrated a short term frequency stability in the range 10-14 to a few times 10-16. The main application for these oscillators is as flywheel oscillators for the next generation of passive atomic frequency standards, and as local oscillators in space telemetry ground stations to clean up the transmitter close in phase noise. Fractional frequency stabilities of passive atomic frequency standards are now approaching 3 x10^-14 /τ where τ is the measurement time, limited only by the number of atoms that are being interrogated. This requires an interrogation oscillator whose short-term stability is of the order of 10-14 or better, which cannot be provided by present-day quartz technology. Ultrastable cryogenic microwave oscillators are based on resonators which have very high electrical Q-factors. The resolution of the resonator's linewidth is typically limited by electronics noise to about 1ppm and hence Q-factors in excess of 108 are required. As these are only attained in superconducting cavities or sapphire resonators at low temperatures, use of liquid helium cooling is mandatory, which has so far restricted these oscillators to the research or metrology laboratory. Recently, there has been an effort to dispense with the need for liquid helium and make compact flywheel oscillators for the new generation of primary frequency standards. Work is under way to achieve this goal in space-borne and mobile liquid-nitrogen-cooled systems. The best cryogenic oscillators developed to date are the ``whispering gallery'' (WG) mode sapphire resonator-oscillators of NASA's Jet Propulsion Laboratory (JPL) and the University of Western Australia (UWA), as well as Stanford University's superconducting cavity stabilized oscillator (SCSO). All of these oscillators have demonstrated frequency stabilities in the range of a few times 10-15 to a few times 10-16. In this contribution we review only liquid-helium-cooled secondary frequency standards, such as those just mentioned, which have attained frequency stabilities of 10-14 or better.

  6. Heat release and flame structure measurements of self-excited acoustically-driven premixed methane flames

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kopp-Vaughan, Kristin M.; Tuttle, Steven G.; Renfro, Michael W.

    An open-open organ pipe burner (Rijke tube) with a bluff-body ring was used to create a self-excited, acoustically-driven, premixed methane-air conical flame, with equivalence ratios ranging from 0.85 to 1.05. The feed tube velocities corresponded to Re = 1780-4450. Coupled oscillations in pressure, velocity, and heat release from the flame are naturally encouraged at resonant frequencies in the Rijke tube combustor. This coupling creates sustainable self-excited oscillations in flame front area and shape. The period of the oscillations occur at the resonant frequency of the combustion chamber when the flame is placed {proportional_to}1/4 of the distance from the bottom ofmore » the tube. In this investigation, the shape of these acoustically-driven flames is measured by employing both OH planar laser-induced fluorescence (PLIF) and chemiluminescence imaging and the images are correlated to simultaneously measured pressure in the combustor. Past research on acoustically perturbed flames has focused on qualitative flame area and heat release relationships under imposed velocity perturbations at imposed frequencies. This study reports quantitative empirical fits with respect to pressure or phase angle in a self-generated pressure oscillation. The OH-PLIF images were single temporal shots and the chemiluminescence images were phase averaged on chip, such that 15 exposures were used to create one image. Thus, both measurements were time resolved during the flame oscillation. Phase-resolved area and heat release variations throughout the pressure oscillation were computed. A relation between flame area and the phase angle before the pressure maximum was derived for all flames in order to quantitatively show that the Rayleigh criterion was satisfied in the combustor. Qualitative trends in oscillating flame area were found with respect to feed tube flow rates. A logarithmic relation was found between the RMS pressure and both the normalized average area and heat release rate for all flames. (author)« less

  7. Inward rectifier potassium current IKir promotes intrinsic pacemaker activity of thalamocortical neurons.

    PubMed

    Amarillo, Yimy; Tissone, Angela I; Mato, Germán; Nadal, Marcela S

    2018-06-01

    Slow repetitive burst firing by hyperpolarized thalamocortical (TC) neurons correlates with global slow rhythms (<4 Hz), which are the physiological oscillations during non-rapid eye movement sleep or pathological oscillations during idiopathic epilepsy. The pacemaker activity of TC neurons depends on the expression of several subthreshold conductances, which are modulated in a behaviorally dependent manner. Here we show that upregulation of the small and neglected inward rectifier potassium current I Kir induces repetitive burst firing at slow and delta frequency bands. We demonstrate this in mouse TC neurons in brain slices by manipulating the Kir maximum conductance with dynamic clamp. We also performed a thorough theoretical analysis that explains how the unique properties of I Kir enable this current to induce slow periodic bursting in TC neurons. We describe a new ionic mechanism based on the voltage- and time-dependent interaction of I Kir and hyperpolarization-activated cationic current I h that endows TC neurons with the ability to oscillate spontaneously at very low frequencies, even below 0.5 Hz. Bifurcation analysis of conductance-based models of increasing complexity demonstrates that I Kir induces bistability of the membrane potential at the same time that it induces sustained oscillations in combination with I h and increases the robustness of low threshold-activated calcium current I T -mediated oscillations. NEW & NOTEWORTHY The strong inwardly rectifying potassium current I Kir of thalamocortical neurons displays a region of negative slope conductance in the current-voltage relationship that generates potassium currents activated by hyperpolarization. Bifurcation analysis shows that I Kir induces bistability of the membrane potential; generates sustained subthreshold oscillations by interacting with the hyperpolarization-activated cationic current I h ; and increases the robustness of oscillations mediated by the low threshold-activated calcium current I T . Upregulation of I Kir in thalamocortical neurons induces repetitive burst firing at slow and delta frequency bands (<4 Hz).

  8. Short-term climate variability and atmospheric teleconnections from satellite-observed outgoing longwave radiation. I Simultaneous relationships. II - Lagged correlations

    NASA Technical Reports Server (NTRS)

    Lau, K.-M.; Chan, P. H.

    1983-01-01

    Attention is given to the low-frequency variability of outgoing longwave radiation (OLR) fluctuations, their possible correlations over different parts of the globe, and their relationships with teleconnections obtained from other meteorological parameters, for example, geopotential and temperature fields. Simultaneous relationships with respect to the Southern Oscillation (Namais, 1978; Barnett, 1981) signal and the reference OLR fluctuation over the equatorial central Pacific are investigated. Emphasis is placed on the relative importance of the Southern Oscillation (SO) signal over preferred regions. Using lag cross-correlation statistics, possible lagged relationships between the tropics and midlatitudes and their relationships with the SO are then investigated. Only features that are consistent with present knowledge of the dynamics of the system are emphasized. Certain features which may not meet rigorous statistical significance tests but yet are either expected a priori from independent observations or are predicted from dynamical theories are also explored.

  9. Infrasonic harmonic tremor and degassing bursts from Halema'uma'u Crater, Kilauea Volcano, Hawaii

    USGS Publications Warehouse

    Fee, David; Garcés, Milton; Patrick, Matt; Chouet, Bernard; Dawson, Phil; Swanson, Donald A.

    2010-01-01

    The formation, evolution, collapse, and subsequent resurrection of a vent within Halema'uma'u Crater, Kilauea Volcano, produced energetic and varied degassing signals recorded by a nearby infrasound array between 2008 and early 2009. After 25 years of quiescence, a vent-clearing explosive burst on 19 March 2008 produced a clear, complex acoustic signal. Near-continuous harmonic infrasonic tremor followed this burst until 4 December 2008, when a period of decreased degassing occurred. The tremor spectra suggest volume oscillation and reverberation of a shallow gas-filled cavity beneath the vent. The dominant tremor peak can be sustained through Helmholtz oscillations of the cavity, while the secondary tremor peak and overtones are interpreted assuming acoustic resonance. The dominant tremor frequency matches the oscillation frequency of the gas emanating from the vent observed by video. Tremor spectra and power are also correlated with cavity geometry and dynamics, with the cavity depth estimated at ~219 m and volume ~3 x 106 m3 in November 2008. Over 21 varied degassing bursts were observed with extended burst durations and frequency content consistent with a transient release of gas exciting the cavity into resonance. Correlation of infrasound with seismicity suggests an open system connecting the atmosphere to the seismic excitation process at depth. Numerous degassing bursts produced very long period (0.03-0.1 Hz) infrasound, the first recorded at Kilauea, indicative of long-duration atmospheric accelerations. Kilauea infrasound appears controlled by the exsolution of gas from the magma, and the interaction of this gas with the conduits and cavities confining it.

  10. VARIABLE TIME-INTERVAL GENERATOR

    DOEpatents

    Gross, J.E.

    1959-10-31

    This patent relates to a pulse generator and more particularly to a time interval generator wherein the time interval between pulses is precisely determined. The variable time generator comprises two oscillators with one having a variable frequency output and the other a fixed frequency output. A frequency divider is connected to the variable oscillator for dividing its frequency by a selected factor and a counter is used for counting the periods of the fixed oscillator occurring during a cycle of the divided frequency of the variable oscillator. This defines the period of the variable oscillator in terms of that of the fixed oscillator. A circuit is provided for selecting as a time interval a predetermined number of periods of the variable oscillator. The output of the generator consists of a first pulse produced by a trigger circuit at the start of the time interval and a second pulse marking the end of the time interval produced by the same trigger circuit.

  11. Searching for oscillations in the primordial power spectrum. II. Constraints from Planck data

    NASA Astrophysics Data System (ADS)

    Meerburg, P. Daniel; Spergel, David N.; Wandelt, Benjamin D.

    2014-03-01

    In this second of two papers we apply our recently developed code to search for resonance features in the Planck CMB temperature data. We search both for log-spaced oscillations or linear-spaced oscillations and compare our findings with results of our WMAP9 analysis and the Planck team analysis [P. A. R. Ade et al. (Planck Collaboration>), arXiv:1303.5082]. While there are hints of log-spaced resonant features present in the WMAP9 data, the significance of these features weaken with more data. With more accurate small scale measurements, we also find that the best-fit frequency has shifted and the amplitude has been reduced. We confirm the presence of a several low frequency peaks, earlier identified by the Planck team, but with a better improvement of fit (Δχeff2˜12). We further investigate this improvement by allowing the lensing potential to vary as well, showing mild correlation between the amplitude of the oscillations and the lensing amplitude. We find that the improvement of the fit increases even more (Δχeff2˜14) for the low frequencies that modify the spectrum in a way that mimics the lensing effect. Since these features were not present in the WMAP data, they are primarily due to better measurements of Planck at small angular scales. For linear-spaced oscillations we find a maximum Δχeff2˜13 scanning two orders of magnitude in frequency space, and the biggest improvements are at extremely high frequencies. Again, we recover a best-fit frequency very close to the one found in WMAP9, which confirms that the fit improvement is driven by low ℓ. Further comparisons with WMAP9 show Planck contains many more features, both for linear- and log-spaced oscillations, but with a smaller improvement of fit. We discuss the improvement as a function of the number of modes and study the effect of the 217 GHz map, which appears to drive most of the improvement for log-spaced oscillations. Two points strongly suggest that the detected features are fitting a combination of the noise and the dip at ℓ˜1800 in the 217 GHz map: the fit improvement mostly comes from a small range of ℓ, and comparison with simulations shows that the fit improvement is consistent with a statistical fluctuation. We conclude that none of the detected features are statistically significant.

  12. Microbar sensor

    DOEpatents

    Wachter, Eric A.; Thundat, Thomas G.

    1995-01-01

    A mass microsensor is fabricated with a microcantilever oscillated by a piezoelectric transducer. A chemical coating having absorptive or adsorptive affinity for a specifically targeted chemical or compound is applied to the microcantilever for oscillation in the monitored atmosphere. Molecules of the targeted chemical attach to the microcantilever coating resulting in an oscillating mass increase which influences the resonant frequency of the microcantilever oscillation. The rate at which the coated microcantilever accumulates the target chemical is functional of the target chemical concentration. Consequently, the extent of microcantilever oscillation frequency change is related to the concentration of the target chemical within the monitored atmosphere. Such oscillation frequency changes are detected by a center-crossing photodiode which responds to a laser diode beam reflected from the microcantilever surface resulting in an output frequency from the photodiode that is synchronous with the microcantilever frequency.

  13. Crystal oscillators using negative voltage gain, single pole response amplifiers

    NASA Technical Reports Server (NTRS)

    Kleinberg, Leonard L. (Inventor)

    1989-01-01

    A simple and inexpensive crystal oscillator is provided which employs negative voltage gain, single pole response amplifiers. The amplifiers may include such configurations as gate inverters, operational amplifiers and conventional bipolar transistor amplifiers, all of which operate at a frequency which is on the roll-off portion of their gain versus frequency curve. Several amplifier feedback circuit variations are employed to set desired bias levels and to allow the oscillator to operate at the crystal's fundamental frequency or at an overtone of the fundamental frequency. The oscillator is made less expensive than comparable oscillators by employing relatively low frequency amplifiers and operating them at roll-off, at frequencies beyond which they are customarily used. Simplicity is provided because operation at roll-off eliminates components ordinarily required in similar circuits to provide sufficient phase-shift in the feedback circuitry for oscillation to occur.

  14. Frequency Regulation and Oscillation Damping Contributions of Variable-Speed Wind Generators in the U.S. Eastern Interconnection (EI)

    DOE PAGES

    Liu, Yong; Gracia, Jose R,; King, Jr, Thomas J.; ...

    2014-05-16

    The U.S. Eastern Interconnection (EI) is one of the largest electric power grids in the world and is expected to have difficulties in dealing with frequency regulation and oscillation damping issues caused by the increasing wind power. On the other side, variable-speed wind generators can actively engage in frequency regulation or oscillation damping with supplementary control loops. This paper creates a 5% wind power penetration simulation scenario based on the 16 000-bus EI system dynamic model and developed the user-defined wind electrical control model in PSS (R) E that incorporates additional frequency regulation and oscillation damping control loops. We evaluatedmore » the potential contributions of variable-speed wind generations to the EI system frequency regulation and oscillation damping, and simulation results demonstrate that current and future penetrations of wind power are promising in the EI system frequency regulation and oscillation damping.« less

  15. Low-frequency oscillations in Hall thrusters

    NASA Astrophysics Data System (ADS)

    Wei, Li-Qiu; Han, Liang; Yu, Da-Ren; Guo, Ning

    2015-05-01

    In this paper, we summarize the research development of low-frequency oscillations in the last few decades. The findings of physical mechanism, characteristics and stabilizing methods of low-frequency oscillations are discussed. It shows that it is unreasonable and incomplete to model an ionization region separately to analyze the physical mechanism of low-frequency oscillations. Electro-dynamics as well as the formation conditions of ionization distribution play an important role in characteristics and stabilizing of low-frequency oscillations. Understanding the physical mechanism and characteristics of low- frequency oscillations thoroughly and developing a feasible method stabilizing this instability are still important research subjects. Project supported by the National Natural Science Foundation of China (Grant No. 51477035), the Fundamental Research Funds for the Central Universities, China (Grant No. HIT.NSRIF 2015064), and the Open Research Fund Program of State Key Laboratory of Cryogenic Vacuum Technology and Physics, China (Grant No. ZDK201304).

  16. Analysis of high-frequency oscillations in mutually-coupled nano-lasers.

    PubMed

    Han, Hong; Shore, K Alan

    2018-04-16

    The dynamics of mutually coupled nano-lasers has been analyzed using rate equations which include the Purcell cavity-enhanced spontaneous emission factor F and the spontaneous emission coupling factor β. It is shown that in the mutually-coupled system, small-amplitude oscillations with frequencies of order 100 GHz are generated and are maintained with remarkable stability. The appearance of such high-frequency oscillations is associated with the effective reduction of the carrier lifetime for larger values of the Purcell factor, F, and spontaneous coupling factor, β. In mutually-coupled nano-lasers the oscillation frequency changes linearly with the frequency detuning between the lasers. For non-identical bias currents, the oscillation frequency of mutually-coupled nano-lasers also increases with bias current. The stability of the oscillations which appear in mutually coupled nano-lasers offers opportunities for their practical applications and notably in photonic integrated circuits.

  17. Discovery of Nearly Coherent Oscillations with a Frequency of approximately 567 Hz During Type I X-ray Bursts of the X-ray Transient and Eclipsing Binary X1658-298

    NASA Technical Reports Server (NTRS)

    Wijnands, Rudy; Strohmayer, Tod; Franco, Lucia M.; White, Nicholas E. (Technical Monitor)

    2001-01-01

    We report the discovery of nearly coherent oscillations with a frequency of approximately 567 Hz during type I X-ray bursts from the X-ray transient and eclipsing binary X1658-298. If these oscillations are directly related to the neutron star rotation, then the spin period of the neutron star in X1658-298 is approximately 1.8 ms. The oscillations can be present during the rise or decay phase of the bursts. Oscillations during the decay phase of the bursts show an increase in frequency of approximately 0.5-1 Hz. However, in one particular burst the oscillations reappear at the end of the decay phase at about 571.5 Hz. This represents an increase in oscillation frequency of about 5 Hz, which is the largest frequency change seen so far in a burst oscillation. It is unclear if such a large change can be accommodated by present models used to explain the frequency evolution of the oscillations. The oscillations at 571.5 Hz are unusually soft compared to the oscillations found at 567 Hz. We also observed several bursts during which the oscillations are detected at much lower significance or not at all. Most of these bursts happen during periods of X-ray dipping behavior, suggesting that the X-ray dipping might decrease the amplitude of the oscillations (although several complications exist with this simple picture). We discuss our discovery in the framework of the neutron star spin interpretation.

  18. THE PECULIAR LIGHT CURVE OF THE SYMBIOTIC STAR AX PER OF THE LAST 125 YEARS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leibowitz, Elia M.; Formiggini, Liliana, E-mail: elia@wise.tau.ac.il

    We analyze the optical light curve (LC) of the last 125 years of the symbiotic star AX Per through some remarkable correlations that we discovered in its power spectrum (PS). The data were assembled from the literature and from the American Association of Variable Stars Observers database. A series of six major outbursts dominate the LC. They are presented in the PS as 13 harmonics of the fundamental frequency f {sub a} = 1/P {sub a} = 1/23,172 day{sup –1}. We refer to them as the ''red'' frequencies. Oscillations with the binary periodicity of the system P {sub b} =more » 1/f {sub b} = 681.48 days are also seen in the LC, with particularly large amplitudes during outbursts. The f {sub b} peak in the PS is accompanied by 13 other peaks on each side, which we refer to as the ''blue'' frequencies. A distinct structure in the frequency distribution of the blue peaks, as well as in their peak power, is best interpreted as reflecting beating of the 13 ''red'' frequencies with the binary one. We suggest, following others, that the major outbursts of the system result from events of intense mass loss from the giant star. Mass accretion onto the hot component, partially through the L1 point of the system, took place in the last 125 years at a rate that oscillated with the 13 first harmonics of the f {sub a} frequency. The binary orbit is slightly eccentric and periastron passages induced modulation of the L1 accretion at the binary frequency. Hence the f {sub b} oscillations in the brightness of the star of an amplitude that is modulated by the ''red'' frequencies of the system.« less

  19. Modulation linearization of a frequency-modulated voltage controlled oscillator, part 3

    NASA Technical Reports Server (NTRS)

    Honnell, M. A.

    1975-01-01

    An analysis is presented for the voltage versus frequency characteristics of a varactor modulated VHF voltage controlled oscillator in which the frequency deviation is linearized by using the nonlinear characteristics of a field effect transistor as a signal amplifier. The equations developed are used to calculate the oscillator output frequency in terms of pertinent circuit parameters. It is shown that the nonlinearity exponent of the FET has a pronounced influence on frequency deviation linearity, whereas the junction exponent of the varactor controls total frequency deviation for a given input signal. A design example for a 250 MHz frequency modulated oscillator is presented.

  20. Dynamic Neural State Identification in Deep Brain Local Field Potentials of Neuropathic Pain.

    PubMed

    Luo, Huichun; Huang, Yongzhi; Du, Xueying; Zhang, Yunpeng; Green, Alexander L; Aziz, Tipu Z; Wang, Shouyan

    2018-01-01

    In neuropathic pain, the neurophysiological and neuropathological function of the ventro-posterolateral nucleus of the thalamus (VPL) and the periventricular gray/periaqueductal gray area (PVAG) involves multiple frequency oscillations. Moreover, oscillations related to pain perception and modulation change dynamically over time. Fluctuations in these neural oscillations reflect the dynamic neural states of the nucleus. In this study, an approach to classifying the synchronization level was developed to dynamically identify the neural states. An oscillation extraction model based on windowed wavelet packet transform was designed to characterize the activity level of oscillations. The wavelet packet coefficients sparsely represented the activity level of theta and alpha oscillations in local field potentials (LFPs). Then, a state discrimination model was designed to calculate an adaptive threshold to determine the activity level of oscillations. Finally, the neural state was represented by the activity levels of both theta and alpha oscillations. The relationship between neural states and pain relief was further evaluated. The performance of the state identification approach achieved sensitivity and specificity beyond 80% in simulation signals. Neural states of the PVAG and VPL were dynamically identified from LFPs of neuropathic pain patients. The occurrence of neural states based on theta and alpha oscillations were correlated to the degree of pain relief by deep brain stimulation. In the PVAG LFPs, the occurrence of the state with high activity levels of theta oscillations independent of alpha and the state with low-level alpha and high-level theta oscillations were significantly correlated with pain relief by deep brain stimulation. This study provides a reliable approach to identifying the dynamic neural states in LFPs with a low signal-to-noise ratio by using sparse representation based on wavelet packet transform. Furthermore, it may advance closed-loop deep brain stimulation based on neural states integrating multiple neural oscillations.

  1. Dynamic Neural State Identification in Deep Brain Local Field Potentials of Neuropathic Pain

    PubMed Central

    Luo, Huichun; Huang, Yongzhi; Du, Xueying; Zhang, Yunpeng; Green, Alexander L.; Aziz, Tipu Z.; Wang, Shouyan

    2018-01-01

    In neuropathic pain, the neurophysiological and neuropathological function of the ventro-posterolateral nucleus of the thalamus (VPL) and the periventricular gray/periaqueductal gray area (PVAG) involves multiple frequency oscillations. Moreover, oscillations related to pain perception and modulation change dynamically over time. Fluctuations in these neural oscillations reflect the dynamic neural states of the nucleus. In this study, an approach to classifying the synchronization level was developed to dynamically identify the neural states. An oscillation extraction model based on windowed wavelet packet transform was designed to characterize the activity level of oscillations. The wavelet packet coefficients sparsely represented the activity level of theta and alpha oscillations in local field potentials (LFPs). Then, a state discrimination model was designed to calculate an adaptive threshold to determine the activity level of oscillations. Finally, the neural state was represented by the activity levels of both theta and alpha oscillations. The relationship between neural states and pain relief was further evaluated. The performance of the state identification approach achieved sensitivity and specificity beyond 80% in simulation signals. Neural states of the PVAG and VPL were dynamically identified from LFPs of neuropathic pain patients. The occurrence of neural states based on theta and alpha oscillations were correlated to the degree of pain relief by deep brain stimulation. In the PVAG LFPs, the occurrence of the state with high activity levels of theta oscillations independent of alpha and the state with low-level alpha and high-level theta oscillations were significantly correlated with pain relief by deep brain stimulation. This study provides a reliable approach to identifying the dynamic neural states in LFPs with a low signal-to-noise ratio by using sparse representation based on wavelet packet transform. Furthermore, it may advance closed-loop deep brain stimulation based on neural states integrating multiple neural oscillations. PMID:29695951

  2. Fundamental and subharmonic excitation for an oscillator with several tunneling diodes in series

    NASA Technical Reports Server (NTRS)

    Boric-Lubecke, Olga; Pan, Dee-Son; Itoh, Tatsuo

    1995-01-01

    Connecting several tunneling diodes in series shows promise as a method for increasing the output power of these devices as millimeter-wave oscillators. However, due to the negative differential resistance (NDR) region in the dc I-V curve of a single tunneling diode, a circuit using several devices connected in series, and biased simultaneously in the NDR region, is dc unstable. Because of this instability, an oscillator with several tunneling diodes in series has a demanding excitation condition. Excitation using an externally applied RF signal is one approach to solving this problem. This is experimentally demonstrated using an RF source, both with frequency close to as well as with frequency considerably lower than the oscillation frequency. Excitation by an RF (radio frequency) source with a frequency as low as one sixth of the oscillation frequency was demonstrated in a proof-of-principle experiment at 2 GHz, for an oscillator with two tunnel diodes connected in series. Strong harmonics of the oscillation signal were generated as a result of the highly nonlinear dc I-V curve of the tunnel diode and a large signal oscillator design. Third harmonic output power comparable to that of the fundamental was observed in one oscillator circuit. If submillimeter wave resonant-tunneling diodes (RTD's) are used instead of tunnel diodes, this harmonic output may be useful for generating signals at frequencies well into the terahertz range.

  3. Frequency-stabilization of mode-locked laser-based photonic microwave oscillator

    NASA Technical Reports Server (NTRS)

    Yu, Nan; Tu, Meirong; Salik, Ertan; Maleki, Lute

    2005-01-01

    In this paper, we will describe our recent phase-noise measurements of photonic microwave oscillators. We will aslo discuss our investigation of the frequency stability link between the optical and microwave frequencies in the coupled oscillator.

  4. Cochlear microphonic responses to acoustic clicks in guinea pig and their relation with microphonic responses to pure tones.

    PubMed

    Echeverría, E L; Robles, L W

    1983-02-01

    Cochlear microphonic (CM) responses to acoustic transient stimuli were studied at the three more basal turns of the cochlea in the guinea pig. The responses to rarefaction and condensation pressure pulses of less than 100-mus duration were recorded using the differential electrode technique. In some animals the CM response to pure tones was recorded at the same position at which the transient response was obtained. The transient responses recorded at the three turns of the cochlea displayed a damped oscillation at a frequency consistent with the values of cutoff frequency already known for the electrode positions. Some of the responses were significantly less damped than click responses previously reported. There was a good correlation between the cutoff frequency in the frequency response curve and the frequency of oscillation in the transient response for recordings obtained at the same position in the cochlea. A nonlinear effect was observed for changes in stimulus intensity. There was a less than proportional decrease in amplitude of the initial part of the damped oscillation for a decrease of the stimulus intensity, while the late part of the response behaved almost linearly. This nonlinearity observed in the CM transient response could not be explained by a nonlinear characteristic of the sort reported in the basilar membrane of the squirrel monkey by Robles et al. [J. Acoust. Soc. Am. 59, 926-939 (1976)]; rather it seems to be a saturation nonlinearity similar to the one known for sinusoidal stimulation.

  5. Parkinsonian Rest Tremor Is Associated With Modulations of Subthalamic High-Frequency Oscillations.

    PubMed

    Hirschmann, Jan; Butz, Markus; Hartmann, Christian J; Hoogenboom, Nienke; Özkurt, Tolga E; Vesper, Jan; Wojtecki, Lars; Schnitzler, Alfons

    2016-10-01

    High frequency oscillations (>200 Hz) have been observed in the basal ganglia of PD patients and were shown to be modulated by the administration of levodopa and voluntary movement. The objective of this study was to test whether the power of high-frequency oscillations in the STN is associated with spontaneous manifestation of parkinsonian rest tremor. The electromyogram of both forearms and local field potentials from the STN were recorded in 11 PD patients (10 men, age 58 [9.4] years, disease duration 9.2 [6.3] years). Patients were recorded at rest and while performing repetitive hand movements before and after levodopa intake. High-frequency oscillation power was compared across epochs containing rest tremor, tremor-free rest, or voluntary movement and related to the tremor cycle. We observed prominent slow (200-300 Hz) and fast (300-400 Hz) high-frequency oscillations. The ratio between slow and fast high-frequency oscillation power increased when tremor became manifest. This increase was consistent across nuclei (94%) and occurred in medication ON and OFF. The ratio outperformed other potential markers of tremor, such as power at individual tremor frequency, beta power, or low gamma power. For voluntary movement, we did not observe a significant difference when compared with rest or rest tremor. Finally, rhythmic modulations of high-frequency oscillation power occurred within the tremor cycle. Subthalamic high-frequency oscillation power is closely linked to the occurrence of parkinsonian rest tremor. The balance between slow and fast high-frequency oscillation power combines information on motor and medication state. © 2016 International Parkinson and Movement Disorder Society. © 2016 International Parkinson and Movement Disorder Society.

  6. Quantifying the impact of Teleconnections on Hydrologic Regimes in Texas

    NASA Astrophysics Data System (ADS)

    Bhatia, N.; Singh, V. P.; Srivastav, R. K.

    2016-12-01

    Climate change is being alleged to have led to the increased frequency of extreme flooding events and the resulting damages are severe, especially where the flood-plain population densities are higher. Much research in the field of hydroclimatology is focusing on improving real-time flood forecasting models. Recent studies show that, in the state of Texas, extreme regional floods are actually triggered by abruptly higher precipitation intensities. Such intensities are further driven by sea-surface temperature and pressure anomalies, defined by certain patterns of teleconnections. In this study, climate variability is defined on the basis of five major Atlantic and Pacific Ocean related teleconnections: (i) Atlantic Multidecadal Oscillation (AMO), (ii) North Atlantic Oscillation (NAO), (iii) Pacific Decadal Oscillation (PDO), (iv) Pacific North American Pattern (PNA), and (v) Southern Oscillation Index (SOI). Hydrologic extremes will be modeled using probabilistic distributions. Leave-One-Out-Test (LOOT) will be employed to address the outliers in the extremes, and to eventually obtain the robust correlation coefficient. The variation in the effect of most correlated teleconnection with respect to hydrologic attributes will be investigated for the entire state. This study will attempt to identify potential teleconnection inputs for data-driven hydrologic models under varying climatic conditions.

  7. Stress-induced birefringence in the isotropic phases of lyotropic mixtures

    NASA Astrophysics Data System (ADS)

    Fernandes, P. R. G.; Maki, J. N.; Gonçalves, L. B.; de Oliveira, B. F.; Mukai, H.

    2018-02-01

    In this work, the frequency dependence of the known mechano-optical effect which occurs in the micellar isotropic phases (I ) of mixtures of potassium laurate (KL), decanol (DeOH), and water is investigated in the range from 200 mHz to 200 Hz . In order to fit the experimental data, a model of superimposed damped harmonic oscillators is proposed. In this phenomenological approach, the micelles (microscopic oscillators) interact very weakly with their neighbors. Due to shape anisotropy of the basic structures, each oscillator i (i =1 ,2 ,3 ,...,N ) remains in its natural oscillatory rotational movement around its axes of symmetry with a frequency ω0 i. The system will be in the resonance state when the frequency of the driving force ω reaches a value near ω0 i. This phenomenological approach shows excellent agreement with the experimental data. One can find f ˜2.5 , 9.0, and 4.0 Hz as fundamental frequencies of the micellar isotropic phases I , I1, and I2, respectively. The different micellar isotropic phases I , I1, and I2 that we find in the phase diagram of the KL-DeOH-water mixture are a consequence of possible differences in the intermicellar correlation lengths. This work reinforces the possibilities of technological applications of these phases in devices such as mechanical vibration sensors.

  8. Crosslinking EEG time-frequency decomposition and fMRI in error monitoring.

    PubMed

    Hoffmann, Sven; Labrenz, Franziska; Themann, Maria; Wascher, Edmund; Beste, Christian

    2014-03-01

    Recent studies implicate a common response monitoring system, being active during erroneous and correct responses. Converging evidence from time-frequency decompositions of the response-related ERP revealed that evoked theta activity at fronto-central electrode positions differentiates correct from erroneous responses in simple tasks, but also in more complex tasks. However, up to now it is unclear how different electrophysiological parameters of error processing, especially at the level of neural oscillations are related, or predictive for BOLD signal changes reflecting error processing at a functional-neuroanatomical level. The present study aims to provide crosslinks between time domain information, time-frequency information, MRI BOLD signal and behavioral parameters in a task examining error monitoring due to mistakes in a mental rotation task. The results show that BOLD signal changes reflecting error processing on a functional-neuroanatomical level are best predicted by evoked oscillations in the theta frequency band. Although the fMRI results in this study account for an involvement of the anterior cingulate cortex, middle frontal gyrus, and the Insula in error processing, the correlation of evoked oscillations and BOLD signal was restricted to a coupling of evoked theta and anterior cingulate cortex BOLD activity. The current results indicate that although there is a distributed functional-neuroanatomical network mediating error processing, only distinct parts of this network seem to modulate electrophysiological properties of error monitoring.

  9. Nonuniform gyrotropic oscillation of skyrmion in a nanodisk

    NASA Astrophysics Data System (ADS)

    Xuan, Shengjie; Liu, Yan

    2018-04-01

    It was predicted that magnetic skyrmions have potential application in the spin nano-oscillators. The oscillation frequency is a key parameter. In this paper, we study the skyrmion relaxation in a FeGe nanodisk and find that the oscillation frequency depends on the skyrmion position. The relaxation process is associated with the variation of skyrmion diameter. By analyzing the system energy, we believe that the nonuniform gyrotropic oscillation frequency is due to the change of the skyrmion diameter.

  10. Surprises of the Transformer as a Coupled Oscillator System

    ERIC Educational Resources Information Center

    Silva, J. P.; Silvestre, A. J.

    2008-01-01

    We study a system of two RLC oscillators coupled through a variable mutual inductance. The system is interesting because it exhibits some peculiar features of coupled oscillators: (i) there are two natural frequencies; (ii) in general, the resonant frequencies do not coincide with the natural frequencies; (iii) the resonant frequencies of both…

  11. Weld pool oscillation during pulsed GTA welding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aendenroomer, A.J.R.; Ouden, G. den

    1996-12-31

    This paper deals with weld pool oscillation during pulsed GTA welding and with the possibility to use this oscillation for in-process control of weld penetration. Welding experiments were carried out under different welding conditions. During welding the weld pool was triggered into oscillation by the normal welding pulses or by extra current pulses. The oscillation frequency was measured both during the pulse time and during the base time by analyzing the arc voltage variation using a Fast Fourier Transformation program. Optimal results are obtained when full penetration occurs during the pulse time and partial penetration during the base time. Undermore » these conditions elliptical overlapping spot welds are formed. In the case of full penetration the weld pool oscillates in a low frequency mode (membrane oscillation), whereas in the case of partial penetration the weld pool oscillates in a high frequency mode (surface oscillation). Deviation from the optimal welding conditions occurs when high frequency oscillation is observed during both pulse time and base time (underpenetration) or when low frequency oscillation is observed during both pulse time and base time (overpenetration). In line with these results a penetration sensing system with feedback control was designed, based on the criterion that optimal weld penetration is achieved when two peaks are observed in the frequency distribution. The feasibility of this sensing system for orbital tube welding was confirmed by the results of experiments carried out under various welding conditions.« less

  12. The effects of ion channel blockers validate the conductance-based model of saccadic oscillations

    PubMed Central

    Shaikh, Aasef G.; Zee, David S.; Optican, Lance M.; Miura, Kenichiro; Ramat, Stefano; Leigh, R. John

    2012-01-01

    Conductance-based models of reciprocally inhibiting burst neurons suggest that intrinsic membrane properties and postinhibitory rebound (PIR) determine the amplitude and frequency of saccadic oscillations. Reduction of the low-threshold calcium currents (IT) in the model decreased the amplitude but increased the frequency of the simulated oscillations. Combined reduction of hyperpolarization-activated cation current (Ih) and IT in the model abolished the simulated oscillations. We measured the effects of a selective blocker of IT (ethosuximide) in healthy subjects on the amplitude and frequency of saccadic oscillations evoked by eye closure and of a nonselective blocker of Ih and IT (propronolol) in a patient with microsaccadic oscillation and limb tremor syndrome (mSOLT). Ethosuximide significantly reduced the amplitude but increased the frequency of the saccadic oscillations during eye closure in healthy subjects. Propranolol abolished saccadic oscillations in the mSOLT patient. These results support the hypothetical role of postinhibitory rebound, Ih, and IT, in generation of saccadic oscillations and determining their kinematic properties. PMID:21950976

  13. EEG Beta Oscillations in the Temporoparietal Area Related to the Accuracy in Estimating Others' Preference

    PubMed Central

    Park, Jonghyeok; Kim, Hackjin; Sohn, Jeong-Woo; Choi, Jong-ryul; Kim, Sung-Phil

    2018-01-01

    Humans often attempt to predict what others prefer based on a narrow slice of experience, called thin-slicing. According to the theoretical bases for how humans can predict the preference of others, one tends to estimate the other's preference using a perceived difference between the other and self. Previous neuroimaging studies have revealed that the network of dorsal medial prefrontal cortex (dmPFC) and right temporoparietal junction (rTPJ) is related to the ability of predicting others' preference. However, it still remains unknown about the temporal patterns of neural activities for others' preference prediction through thin-slicing. To investigate such temporal aspects of neural activities, we investigated human electroencephalography (EEG) recorded during the task of predicting the preference of others while only a facial picture of others was provided. Twenty participants (all female, average age: 21.86) participated in the study. In each trial of the task, participants were shown a picture of either a target person or self for 3 s, followed by the presentation of a movie poster over which participants predicted the target person's preference as liking or disliking. The time-frequency EEG analysis was employed to analyze temporal changes in the amplitudes of brain oscillations. Participants could predict others' preference for movies with accuracy of 56.89 ± 3.16% and 10 out of 20 participants exhibited prediction accuracy higher than a chance level (95% interval). There was a significant difference in the power of the parietal alpha (10~13 Hz) oscillation 0.6~0.8 s after the onset of poster presentation between the cases when participants predicted others' preference and when they reported self-preference (p < 0.05). The power of brain oscillations at any frequency band and time period during the trial did not show a significant correlation with individual prediction accuracy. However, when we measured differences of the power between the trials of predicting other's preference and reporting self-preference, the right temporal beta oscillations 1.6~1.8 s after the onset of facial picture presentation exhibited a significant correlation with individual accuracy. Our results suggest that right temporoparietal beta oscillations may be correlated with one's ability to predict what others prefer with minimal information. PMID:29479312

  14. EEG Beta Oscillations in the Temporoparietal Area Related to the Accuracy in Estimating Others' Preference.

    PubMed

    Park, Jonghyeok; Kim, Hackjin; Sohn, Jeong-Woo; Choi, Jong-Ryul; Kim, Sung-Phil

    2018-01-01

    Humans often attempt to predict what others prefer based on a narrow slice of experience, called thin-slicing. According to the theoretical bases for how humans can predict the preference of others, one tends to estimate the other's preference using a perceived difference between the other and self. Previous neuroimaging studies have revealed that the network of dorsal medial prefrontal cortex (dmPFC) and right temporoparietal junction (rTPJ) is related to the ability of predicting others' preference. However, it still remains unknown about the temporal patterns of neural activities for others' preference prediction through thin-slicing. To investigate such temporal aspects of neural activities, we investigated human electroencephalography (EEG) recorded during the task of predicting the preference of others while only a facial picture of others was provided. Twenty participants (all female, average age: 21.86) participated in the study. In each trial of the task, participants were shown a picture of either a target person or self for 3 s, followed by the presentation of a movie poster over which participants predicted the target person's preference as liking or disliking. The time-frequency EEG analysis was employed to analyze temporal changes in the amplitudes of brain oscillations. Participants could predict others' preference for movies with accuracy of 56.89 ± 3.16% and 10 out of 20 participants exhibited prediction accuracy higher than a chance level (95% interval). There was a significant difference in the power of the parietal alpha (10~13 Hz) oscillation 0.6~0.8 s after the onset of poster presentation between the cases when participants predicted others' preference and when they reported self-preference ( p < 0.05). The power of brain oscillations at any frequency band and time period during the trial did not show a significant correlation with individual prediction accuracy. However, when we measured differences of the power between the trials of predicting other's preference and reporting self-preference, the right temporal beta oscillations 1.6~1.8 s after the onset of facial picture presentation exhibited a significant correlation with individual accuracy. Our results suggest that right temporoparietal beta oscillations may be correlated with one's ability to predict what others prefer with minimal information.

  15. Microstructure and Solidification Crack Susceptibility of Al 6014 Molten Alloy Subjected to a Spatially Oscillated Laser Beam.

    PubMed

    Kang, Minjung; Han, Heung Nam; Kim, Cheolhee

    2018-04-23

    Oscillating laser beam welding for Al 6014 alloy was performed using a single mode fiber laser and two-axis scanner system. Its effect on the microstructural evolution of the fusion zone was investigated. To evaluate the influence of oscillation parameters, self-restraint test specimens were fabricated with different beam patterns, widths, and frequencies. The behavior of hot cracking propagation was analyzed by high-speed camera and electron backscatter diffraction. The behavior of crack propagation was observed to be highly correlated with the microstructural evolution of the fusion zone. For most oscillation conditions, the microstructure resembled that of linear welds. A columnar structure was formed near the fusion line and an equiaxed structure was generated at its center. The wide equiaxed zone of oscillation welding increased solidification crack susceptibility. For an oscillation with an infinite-shaped scanning pattern at 100 Hz and 3.5 m/min welding speed, the bead width, solidification microstructure, and the width of the equiaxed zone at the center of fusion fluctuated. Furthermore, the equiaxed and columnar regions alternated periodically, which could reduce solidification cracking susceptibility.

  16. Inherent rhythm of smooth muscle cells in rat mesenteric arterioles: An eigensystem formulation

    NASA Astrophysics Data System (ADS)

    Ho, I. Lin; Moshkforoush, Arash; Hong, Kwangseok; Meininger, Gerald A.; Hill, Michael A.; Tsoukias, Nikolaos M.; Kuo, Watson

    2016-04-01

    On the basis of experimental data and mathematical equations in the literature, we remodel the ionic dynamics of smooth muscle cells (SMCs) as an eigensystem formulation, which is valid for investigating finite variations of variables from the equilibrium such as in common experimental operations. This algorithm provides an alternate viewpoint from frequency-domain analysis and enables one to probe functionalities of SMCs' rhythm by means of a resonance-related mechanism. Numerical results show three types of calcium oscillations of SMCs in mesenteric arterioles: spontaneous calcium oscillation, agonist-dependent calcium oscillation, and agonist-dependent calcium spike. For simple single and double SMCs, we demonstrate properties of synchronization among complex signals related to calcium oscillations, and show different correlation relations between calcium and voltage signals for various synchronization and resonance conditions. For practical cell clusters, our analyses indicate that the rhythm of SMCs could (1) benefit enhancements of signal communications among remote cells, (2) respond to a significant calcium peaking against transient stimulations for triggering globally oscillating modes, and (3) characterize the globally oscillating modes via frog-leap (non-molecular-diffusion) calcium waves across inhomogeneous SMCs.

  17. Microstructure and Solidification Crack Susceptibility of Al 6014 Molten Alloy Subjected to a Spatially Oscillated Laser Beam

    PubMed Central

    Kang, Minjung; Han, Heung Nam

    2018-01-01

    Oscillating laser beam welding for Al 6014 alloy was performed using a single mode fiber laser and two-axis scanner system. Its effect on the microstructural evolution of the fusion zone was investigated. To evaluate the influence of oscillation parameters, self-restraint test specimens were fabricated with different beam patterns, widths, and frequencies. The behavior of hot cracking propagation was analyzed by high-speed camera and electron backscatter diffraction. The behavior of crack propagation was observed to be highly correlated with the microstructural evolution of the fusion zone. For most oscillation conditions, the microstructure resembled that of linear welds. A columnar structure was formed near the fusion line and an equiaxed structure was generated at its center. The wide equiaxed zone of oscillation welding increased solidification crack susceptibility. For an oscillation with an infinite-shaped scanning pattern at 100 Hz and 3.5 m/min welding speed, the bead width, solidification microstructure, and the width of the equiaxed zone at the center of fusion fluctuated. Furthermore, the equiaxed and columnar regions alternated periodically, which could reduce solidification cracking susceptibility. PMID:29690630

  18. A preliminary analysis of low frequency pressure oscillations in hybrid rocket motors

    NASA Technical Reports Server (NTRS)

    Jenkins, Rhonald M.

    1994-01-01

    Past research with hybrid rockets has suggested that certain motor operating conditions are conducive to the formation of pressure oscillations, or flow instabilities, within the motor combustion chamber. These combustion-related vibrations or pressure oscillations may be encountered in virtually any type of rocket motor and typically fall into three frequency ranges: low frequency oscillations (0-300 Hz); intermediate frequency oscillations (400-1000 Hz); and high frequency oscillations (greater than 1000 Hz). In general, combustion instability is characterized by organized pressure oscillations occurring at well-defined intervals with pressure peaks that may maintain themselves, grow, or die out. Usually, such peaks exceed +/- 5% of the mean chamber pressure. For hybrid motors, these oscillations have been observed to grow to a limiting amplitude which may be dependent on factors such as fuel characteristics, oxidizer injector characteristics, average chamber pressure, oxidizer mass flux, combustion chamber length, and grain geometry. The approach taken in the present analysis is to develop a modified chamber length, L, instability theory which accounts for the relationship between pressure and oxidizer to fuel concentration ratio in the motor.

  19. Mean-field modeling of the basal ganglia-thalamocortical system. II Dynamics of parkinsonian oscillations.

    PubMed

    van Albada, S J; Gray, R T; Drysdale, P M; Robinson, P A

    2009-04-21

    Neuronal correlates of Parkinson's disease (PD) include a shift to lower frequencies in the electroencephalogram (EEG) and enhanced synchronized oscillations at 3-7 and 7-30 Hz in the basal ganglia, thalamus, and cortex. This study describes the dynamics of a recent physiologically based mean-field model of the basal ganglia-thalamocortical system, and shows how it accounts for many key electrophysiological correlates of PD. Its detailed functional connectivity comprises partially segregated direct and indirect pathways through two populations of striatal neurons, a hyperdirect pathway involving a corticosubthalamic projection, thalamostriatal feedback, and local inhibition in striatum and external pallidum (GPe). In a companion paper, realistic steady-state firing rates were obtained for the healthy state, and after dopamine loss modeled by weaker direct and stronger indirect pathways, reduced intrapallidal inhibition, lower firing thresholds of the GPe and subthalamic nucleus (STN), a stronger projection from striatum to GPe, and weaker cortical interactions. Here it is shown that oscillations around 5 and 20 Hz can arise with a strong indirect pathway, which also causes increased synchronization throughout the basal ganglia. Furthermore, increased theta power with progressive nigrostriatal degeneration is correlated with reduced alpha power and peak frequency, in agreement with empirical results. Unlike the hyperdirect pathway, the indirect pathway sustains oscillations with phase relationships that coincide with those found experimentally. Alterations in the responses of basal ganglia to transient stimuli accord with experimental observations. Reduced cortical gains due to both nigrostriatal and mesocortical dopamine loss lead to slower changes in cortical activity and may be related to bradykinesia. Finally, increased EEG power found in some studies may be partly explained by a lower effective GPe firing threshold, reduced GPe-GPe inhibition, and/or weaker intracortical connections in parkinsonian patients. Strict separation of the direct and indirect pathways is not necessary to obtain these results.

  20. Neural Entrainment to Polyrhythms: A Comparison of Musicians and Non-musicians.

    PubMed

    Stupacher, Jan; Wood, Guilherme; Witte, Matthias

    2017-01-01

    Music can be thought of as a dynamic path over time. In most cases, the rhythmic structure of this path, such as specific sequences of strong and weak beats or recurring patterns, allows us to predict what and particularly when sounds are going to happen. Without this ability we would not be able to entrain body movements to music, like we do when we dance. By combining EEG and behavioral measures, the current study provides evidence illustrating the importance of ongoing neural oscillations at beat-related frequencies-i.e., neural entrainment-for tracking and predicting musical rhythms. Participants (13 musicians and 13 non-musicians) listened to drum rhythms that switched from a quadruple rhythm to a 3-over-4 polyrhythm. After a silent period of ~2-3 s, participants had to decide whether a target stimulus was presented on time with the triple beat of the polyrhythm, too early, or too late. Results showed that neural oscillations reflected the rhythmic structure of both the simple quadruple rhythm and the more complex polyrhythm with no differences between musicians and non-musicians. During silent periods, the observation of time-frequency plots and more commonly used frequency spectra analyses suggest that beat-related neural oscillations were more pronounced in musicians compared to non-musicians. Neural oscillations during silent periods are not driven by an external input and therefore are thought to reflect top-down controlled endogenous neural entrainment. The functional relevance of endogenous neural entrainment was demonstrated by a positive correlation between the amplitude of task-relevant neural oscillations during silent periods and the number of correctly identified target stimuli. In sum, our findings add to the evidence supporting the neural resonance theory of pulse and meter. Furthermore, they indicate that beat-related top-down controlled neural oscillations can exist without external stimulation and suggest that those endogenous oscillations are strengthened by musical expertise. Finally, this study shows that the analysis of neural oscillations can be a useful tool to assess how we perceive and process complex auditory stimuli such as polyrhythms.

  1. Frequency equation for the submicron CMOS ring oscillator using the first order characterization

    NASA Astrophysics Data System (ADS)

    Koithyar, Aravinda; Ramesh, T. K.

    2018-05-01

    By utilizing the first order behavior of the device, an equation for the frequency of operation of the submicron CMOS ring oscillator is presented. A 5-stage ring oscillator is utilized as the initial design, with different Beta ratios, for the computation of the operating frequency. Later on, the circuit simulation is performed from 5-stage till 23-stage, with the range of oscillating frequency being 3.0817 and 0.6705 GHz respectively. It is noted that the output frequency is inversely proportional to the square of the device length, and when the value of Beta ratio is used as 2.3, a difference of 3.64% is observed on an average, in between the computed and the simulated values of frequency. As an outcome, the derived equation can be utilized, with the inclusion of an empirical constant in general, for arriving at the ring oscillator circuit’s output frequency.

  2. Method to improve optical parametric oscillator beam quality

    DOEpatents

    Smith, Arlee V.; Alford, William J.; Bowers, Mark S.

    2003-11-11

    A method to improving optical parametric oscillator (OPO) beam quality having an optical pump, which generates a pump beam at a pump frequency greater than a desired signal frequency, a nonlinear optical medium oriented so that a signal wave at the desired signal frequency and a corresponding idler wave are produced when the pump beam (wave) propagates through the nonlinear optical medium, resulting in beam walk off of the signal and idler waves, and an optical cavity which directs the signal wave to repeatedly pass through the nonlinear optical medium, said optical cavity comprising an equivalently even number of non-planar mirrors that produce image rotation on each pass through the nonlinear optical medium. Utilizing beam walk off where the signal wave and said idler wave have nonparallel Poynting vectors in the nonlinear medium and image rotation, a correlation zone of distance equal to approximately .rho.L.sub.crystal is created which, through multiple passes through the nonlinear medium, improves the beam quality of the OPO output.

  3. Beta-gamma burst stimulations of the inferior olive induce high-frequency oscillations in the deep cerebellar nuclei.

    PubMed

    Cheron, Julian; Cheron, Guy

    2018-02-20

    The cerebellum displays various sorts of rhythmic activities covering both low- and high-frequency oscillations. These cerebellar high-frequency oscillations were observed in the cerebellar cortex. Here, we hypothesised that not only is the cerebellar cortex a generator of high-frequency oscillations but also that the deep cerebellar nuclei may also play a similar role. Thus, we analysed local field potentials and single-unit activities in the deep cerebellar nuclei before, during and after electric stimulation in the inferior olive of awake mice. A high-frequency oscillation of 350 Hz triggered by the stimulation of the inferior olive, within the beta-gamma range, was observed in the deep cerebellar nuclei. The amplitude and frequency of the oscillation were independent of the frequency of stimulation. This oscillation emerged during the period of stimulation and persisted after the end of the stimulation. The oscillation coincided with the inhibition of deep cerebellar neurons. As the inhibition of the deep cerebellar nuclei is related to inhibitory inputs from Purkinje cells, we speculate that the oscillation represents the unmasking of the synchronous activation of another subtype of deep cerebellar neuronal subtype, devoid of GABA receptors and under the direct control of the climbing fibres from the inferior olive. Still, the mechanism sustaining this oscillation remains to be deciphered. Our study sheds new light on the role of the olivo-cerebellar loop as the final output control of the intercerebellar circuitry. © 2018 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  4. Mode transition of a Hall thruster discharge plasma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hara, Kentaro, E-mail: kenhara@umich.edu; Sekerak, Michael J., E-mail: msekerak@umich.edu; Boyd, Iain D.

    2014-05-28

    A Hall thruster is a cross-field plasma device used for spacecraft propulsion. An important unresolved issue in the development of Hall thrusters concerns the effect of discharge oscillations in the range of 10–30 kHz on their performance. The use of a high speed Langmuir probe system and ultra-fast imaging of the discharge plasma of a Hall thruster suggests that the discharge oscillation mode, often called the breathing mode, is strongly correlated to an axial global ionization mode. Stabilization of the global oscillation mode is achieved as the magnetic field is increased and azimuthally rotating spokes are observed. A hybrid-direct kinetic simulationmore » that takes into account the transport of electronically excited atoms is used to model the discharge plasma of a Hall thruster. The predicted mode transition agrees with experiments in terms of the mean discharge current, the amplitude of discharge current oscillation, and the breathing mode frequency. It is observed that the stabilization of the global oscillation mode is associated with reduced electron transport that suppresses the ionization process inside the channel. As the Joule heating balances the other loss terms including the effects of wall loss and inelastic collisions, the ionization oscillation is damped, and the discharge oscillation stabilizes. A wide range of the stable operation is supported by the formation of a space charge saturated sheath that stabilizes the electron axial drift and balances the Joule heating as the magnetic field increases. Finally, it is indicated from the numerical results that there is a strong correlation between the emitted light intensity and the discharge current.« less

  5. Stable And Oscillating Acoustic Levitation

    NASA Technical Reports Server (NTRS)

    Barmatz, Martin B.; Garrett, Steven L.

    1988-01-01

    Sample stability or instability determined by levitating frequency. Degree of oscillation of acoustically levitated object along axis of levitation chamber controlled by varying frequency of acoustic driver for axis above or below frequency of corresponding chamber resonance. Stabilization/oscillation technique applied in normal Earth gravity, or in absence of gravity to bring object quickly to rest at nominal levitation position or make object oscillate in desired range about that position.

  6. Dependence of synchronization on frequency mismatch and network configuration in chemo-mechanical oscillators

    NASA Astrophysics Data System (ADS)

    Kumar, Pawan; Parmananda, P.

    2018-04-01

    In this paper, synchronization among the mercury beating heart (MBH) oscillators is studied. In the first set of experiments, two MBH oscillators were taken. Frequency of one oscillator is kept constant and that of the other is increased monotonically. These were then coupled using bidirectional and unidirectional coupling mechanisms separately. Dependence of synchronization on the frequency difference between the two oscillators is investigated. For the second set of experiments involving unidirectional coupling, an ensemble of fifteen oscillators was taken and different configurations of these oscillators were considered. These include an all-to-all network and fractionally distributed master slave configurations. The effect of both the extent of coupling and network configuration on synchronization among these oscillators was investigated.

  7. QPO from the rapid burster

    NASA Astrophysics Data System (ADS)

    Dotani, T.

    1989-11-01

    Strong Quasi-Periodic Oscillations (QPO) in type 2 bursts from the rapid burster with Ginga were detected. The QPD have centroid frequency of approximately 5 and 2 Hz during bursts which lasted for approximately 10 and 30 sec, respectively. The QPO observations were analyzed and the following results were obtained: QPO centroid frequencies have some correlation with burst duration and peak count rate, however the correlations are complicated and the burst parameters do not uniquely determine the QPO centroid frequency; the appearance of the QPO is closely related to the so-called timescale-invariant profile of the bursts; the QPO are significant only in the even numbered peaks of the profile and not in the odd numbered peaks; in most cases the QPO centroid frequency decreases up to approximately 25 percent during a burst. The energy spectra at the QPO peaks and valleys were investigated and the QPO peaks were found to have significantely higher blackbody temperature than the QPD valleys.

  8. Changes in hippocampal theta rhythm and their correlations with speed during different phases of voluntary wheel running in rats.

    PubMed

    Li, J-Y; Kuo, T B J; Hsieh, I-T; Yang, C C H

    2012-06-28

    Hippocampal theta rhythm (4-12 Hz) can be observed during locomotor behavior, but findings on the relationship between locomotion speed and theta frequency are inconsistent if not contradictory. The inconsistency may be because of the difficulties that previous analyses and protocols have had excluding the effects of behavior training. We recorded the first or second voluntary wheel running each day, and assumed that theta frequency and activity are correlated with speed in different running phases. By simultaneously recording electroencephalography, physical activity, and wheel running speed, this experiment explored the theta oscillations during spontaneous running of the 12-h dark period. The recording was completely wireless and allowed the animal to run freely while being recorded in the wheel. Theta frequency and theta power of middle frequency were elevated before running and theta frequency, theta power of middle frequency, physical activity, and running speed maintained persistently high levels during running. The slopes of the theta frequency and theta activity (4-9.5 Hz) during the initial running were different compared to the same values during subsequent running. During the initial running, the running speed was positively correlated with theta frequency and with theta power of middle frequency. Over the 12-h dark period, the running speed did not positively correlate with theta frequency but was significantly correlated with theta power of middle frequency. Thus, theta frequency was associated with running speed only at the initiation of running. Furthermore, theta power of middle frequency was associated with speed and with physical activity during running when chronological order was not taken into consideration. Copyright © 2012 IBRO. Published by Elsevier Ltd. All rights reserved.

  9. Boundary versus bulk behavior of time-dependent correlation functions in one-dimensional quantum systems

    NASA Astrophysics Data System (ADS)

    Eliëns, I. S.; Ramos, F. B.; Xavier, J. C.; Pereira, R. G.

    2016-05-01

    We study the influence of reflective boundaries on time-dependent responses of one-dimensional quantum fluids at zero temperature beyond the low-energy approximation. Our analysis is based on an extension of effective mobile impurity models for nonlinear Luttinger liquids to the case of open boundary conditions. For integrable models, we show that boundary autocorrelations oscillate as a function of time with the same frequency as the corresponding bulk autocorrelations. This frequency can be identified as the band edge of elementary excitations. The amplitude of the oscillations decays as a power law with distinct exponents at the boundary and in the bulk, but boundary and bulk exponents are determined by the same coupling constant in the mobile impurity model. For nonintegrable models, we argue that the power-law decay of the oscillations is generic for autocorrelations in the bulk, but turns into an exponential decay at the boundary. Moreover, there is in general a nonuniversal shift of the boundary frequency in comparison with the band edge of bulk excitations. The predictions of our effective field theory are compared with numerical results obtained by time-dependent density matrix renormalization group (tDMRG) for both integrable and nonintegrable critical spin-S chains with S =1 /2 , 1, and 3 /2 .

  10. A Resonantly Excited Disk-Oscillation Model of High-Frequency QPOs of Microquasars

    NASA Astrophysics Data System (ADS)

    Kato, Shoji

    2012-12-01

    A possible model of twin high-frequency QPOs (HF QPOs) of microquasars is examined. The disk is assumed to have global magnetic fields and to be deformed with a two-armed pattern. In this deformed disk, a set of a two-armed (m = 2) vertical p-mode oscillation and an axisymmetric (m = 0) g-mode oscillation is considered. They resonantly interact through the disk deformation when their frequencies are the same. This resonant interaction amplifies the set of the above oscillations in the case where these two oscillations have wave energies of opposite signs. These oscillations are assumed to be excited most efficiently in the case where the radial group velocities of these two waves vanish at the same place. The above set of oscillations is not unique, depending on the node number n, of oscillations in the vertical direction. We consider that the basic two sets of oscillations correspond to the twin QPOs. The frequencies of these oscillations depend on the disk parameters, such as the strength of the magnetic fields. For observational mass ranges of GRS 1915+ 105, GRO J1655-40, XTE J1550-564, and HEAO H1743-322, the spins of these sources are estimated. High spins of these sources can be described if the disks have weak poloidal magnetic fields as well as toroidal magnetic fields of moderate strength. In this model the 3:2 frequency ratio of high-frequency QPOs is not related to their excitation, but occurs by chance.

  11. A novel optogenetically tunable frequency modulating oscillator

    PubMed Central

    2018-01-01

    Synthetic biology has enabled the creation of biological reconfigurable circuits, which perform multiple functions monopolizing a single biological machine; Such a system can switch between different behaviours in response to environmental cues. Previous work has demonstrated switchable dynamical behaviour employing reconfigurable logic gate genetic networks. Here we describe a computational framework for reconfigurable circuits in E.coli using combinations of logic gates, and also propose the biological implementation. The proposed system is an oscillator that can exhibit tunability of frequency and amplitude of oscillations. Further, the frequency of operation can be changed optogenetically. Insilico analysis revealed that two-component light systems, in response to light within a frequency range, can be used for modulating the frequency of the oscillator or stopping the oscillations altogether. Computational modelling reveals that mixing two colonies of E.coli oscillating at different frequencies generates spatial beat patterns. Further, we show that these oscillations more robustly respond to input perturbations compared to the base oscillator, to which the proposed oscillator is a modification. Compared to the base oscillator, the proposed system shows faster synchronization in a colony of cells for a larger region of the parameter space. Additionally, the proposed oscillator also exhibits lesser synchronization error in the transient period after input perturbations. This provides a strong basis for the construction of synthetic reconfigurable circuits in bacteria and other organisms, which can be scaled up to perform functions in the field of time dependent drug delivery with tunable dosages, and sets the stage for further development of circuits with synchronized population level behaviour. PMID:29389936

  12. A novel optogenetically tunable frequency modulating oscillator.

    PubMed

    Mahajan, Tarun; Rai, Kshitij

    2018-01-01

    Synthetic biology has enabled the creation of biological reconfigurable circuits, which perform multiple functions monopolizing a single biological machine; Such a system can switch between different behaviours in response to environmental cues. Previous work has demonstrated switchable dynamical behaviour employing reconfigurable logic gate genetic networks. Here we describe a computational framework for reconfigurable circuits in E.coli using combinations of logic gates, and also propose the biological implementation. The proposed system is an oscillator that can exhibit tunability of frequency and amplitude of oscillations. Further, the frequency of operation can be changed optogenetically. Insilico analysis revealed that two-component light systems, in response to light within a frequency range, can be used for modulating the frequency of the oscillator or stopping the oscillations altogether. Computational modelling reveals that mixing two colonies of E.coli oscillating at different frequencies generates spatial beat patterns. Further, we show that these oscillations more robustly respond to input perturbations compared to the base oscillator, to which the proposed oscillator is a modification. Compared to the base oscillator, the proposed system shows faster synchronization in a colony of cells for a larger region of the parameter space. Additionally, the proposed oscillator also exhibits lesser synchronization error in the transient period after input perturbations. This provides a strong basis for the construction of synthetic reconfigurable circuits in bacteria and other organisms, which can be scaled up to perform functions in the field of time dependent drug delivery with tunable dosages, and sets the stage for further development of circuits with synchronized population level behaviour.

  13. [Mg2+]o/[Ca2+]o determines Ca2+ response at fertilization: tuning of adult phenotype?

    PubMed

    Ozil, Jean-Pierre; Sainte-Beuve, Thierry; Banrezes, Bernadette

    2017-11-01

    Alteration of the postnatal phenotype has sparked great concern about the developmental impact of culture media used at fertilization. However, the mechanisms and compounds involved are yet to be determined. Here, we used the Ca 2+ responses from mouse eggs fertilized by ICSI as a dynamic and quantitative marker to understand the role of compounds in egg functioning and establish possible correlations with adult phenotypes. We computed 134 Ca 2+ responses from the first to the last oscillation in media with specific formulations. Analyses demonstrate that eggs generated two times as many Ca 2+ oscillations in KSOM as in M16 media (18.8 ± 7.0 vs 9.2 ± 2.5). Moreover, the time increment of the delay between two consecutive oscillations, named TIbO, is the most sensitive coefficient characterizing the mechanism that paces Ca 2+ oscillations once the egg has been fertilized. Neither doubling external free Ca 2+ nor dispermic fertilization increased significantly the total number of Ca 2+ oscillations. In contrast, removing Mg 2+ from the M16 boosted Ca 2+ oscillations to 54.0 ± 35.2. Hence, [Mg 2+ ] o /[Ca 2+ ] o appears to determine the number, duration and frequency of the Ca 2+ oscillations. These changes were correlated with long-term effects. The rate of female's growth was impacted with the 'KSOM' females having only half the fat deposit of 'M16' females. Moreover, adult animals issued from M16 had significantly smaller brain weight vs 'KSOM' and 'control' animals. TIbO is a new Ca 2+ coefficient that gauges the very early functional impact of culture media. It offers the possibility of establishing correlations with postnatal consequences according to IVF medium formulation.Free French abstract: A French translation of this abstract is freely available at http://www.reproduction-online.org/content/154/5/675/suppl/DC2. © 2017 Society for Reproduction and Fertility.

  14. Fast frequency divider circuit using combinational logic

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Helinski, Ryan

    The various technologies presented herein relate to performing on-chip frequency division of an operating frequency of a ring oscillator (RO). Per the various embodiments herein, a conflict between RO size versus operational frequency can be addressed by dividing the output frequency of the RO to a frequency that can be measured on-chip. A frequency divider circuit (comprising NOR gates and latches, for example) can be utilized in conjunction with the RO on the chip. In an embodiment, the frequency divider circuit can include a pair of latches coupled to the RO to facilitate dividing the oscillating frequency of the ROmore » by 2. In another embodiment, the frequency divider circuit can include four latches (operating in pairs) coupled to the RO to facilitate dividing the oscillating frequency of the RO by 4. A plurality of ROs can be MUXed to the plurality of ROs by a single oscillation-counting circuit.« less

  15. Beat-to-Beat Variability of Ventricular Action Potential Duration Oscillates at Low Frequency During Sympathetic Provocation in Humans

    PubMed Central

    Porter, Bradley; van Duijvenboden, Stefan; Bishop, Martin J.; Orini, Michele; Claridge, Simon; Gould, Justin; Sieniewicz, Benjamin J.; Sidhu, Baldeep; Razavi, Reza; Rinaldi, Christopher A.; Gill, Jaswinder S.; Taggart, Peter

    2018-01-01

    Background: The temporal pattern of ventricular repolarization is of critical importance in arrhythmogenesis. Enhanced beat-to-beat variability (BBV) of ventricular action potential duration (APD) is pro-arrhythmic and is increased during sympathetic provocation. Since sympathetic nerve activity characteristically exhibits burst patterning in the low frequency range, we hypothesized that physiologically enhanced sympathetic activity may not only increase BBV of left ventricular APD but also impose a low frequency oscillation which further increases repolarization instability in humans. Methods and Results: Heart failure patients with cardiac resynchronization therapy defibrillator devices (n = 11) had activation recovery intervals (ARI, surrogate for APD) recorded from left ventricular epicardial electrodes alongside simultaneous non-invasive blood pressure and respiratory recordings. Fixed cycle length was achieved by right ventricular pacing. Recordings took place during resting conditions and following an autonomic stimulus (Valsalva). The variability of ARI and the normalized variability of ARI showed significant increases post Valsalva when compared to control (p = 0.019 and p = 0.032, respectively). The oscillatory behavior was quantified by spectral analysis. Significant increases in low frequency (LF) power (p = 0.002) and normalized LF power (p = 0.019) of ARI were seen following Valsalva. The Valsalva did not induce changes in conduction variability nor the LF oscillatory behavior of conduction. However, increases in the LF power of ARI were accompanied by increases in the LF power of systolic blood pressure (SBP) and the rate of systolic pressure increase (dP/dtmax). Positive correlations were found between LF-SBP and LF-dP/dtmax (rs = 0.933, p < 0.001), LF-ARI and LF-SBP (rs = 0.681, p = 0.001) and between LF-ARI and LF-dP/dtmax (rs = 0.623, p = 0.004). There was a strong positive correlation between the variability of ARI and LF power of ARI (rs = 0.679, p < 0.001). Conclusions: In heart failure patients, physiological sympathetic provocation induced low frequency oscillation (~0.1 Hz) of left ventricular APD with a strong positive correlation between the LF power of APD and the BBV of APD. These findings may be of importance in mechanisms underlying stability/instability of repolarization and arrhythmogenesis in humans. PMID:29670531

  16. Non-stationarity in US droughts and implications for water resources planning and management

    NASA Astrophysics Data System (ADS)

    Apurv, T.; Cai, X.

    2017-12-01

    The concepts of return period and reliability are widely used in hydrology for quantifying the risk of extreme events. The conventional way of calculating return period and reliability requires the assumption of stationarity and independence of extreme events in successive years. These assumptions may not be true for droughts since a single drought event can last for more than one year. Further, droughts are known to be influenced by multi-year to multi-decadal oscillations (eg. El Nino Southern Oscillation (ENSO), Atlantic Multidecadal Oscillation (AMO), Pacific Decadal Oscillation (PDO)), which means that the underlying distribution can change with time. In this study, we develop a non-stationary frequency analysis for relating meteorological droughts in the continental US (CONUS) with physical covariates. We calculate the return period and reliability of meteorological droughts in different parts of CONUS by considering the correlation and the non-stationarity in drought events. We then compare the return period and reliability calculated assuming non-stationarity with that calculated assuming stationarity. The difference between the two estimates is used to quantify the extent of non-stationarity in droughts in different parts of CONUS. We also use the non-stationary frequency analysis model for attributing the causes of non-stationarity. Finally we will discuss the implications for water resources planning and management in the United States.

  17. Cross-frequency coupling of brain oscillations in studying motivation and emotion.

    PubMed

    Schutter, Dennis J L G; Knyazev, Gennady G

    2012-03-01

    Research has shown that brain functions are realized by simultaneous oscillations in various frequency bands. In addition to examining oscillations in pre-specified bands, interactions and relations between the different frequency bandwidths is another important aspect that needs to be considered in unraveling the workings of the human brain and its functions. In this review we provide evidence that studying interdependencies between brain oscillations may be a valuable approach to study the electrophysiological processes associated with motivation and emotional states. Studies will be presented showing that amplitude-amplitude coupling between delta-alpha and delta-beta oscillations varies as a function of state anxiety and approach-avoidance-related motivation, and that changes in the association between delta-beta oscillations can be observed following successful psychotherapy. Together these studies suggest that cross-frequency coupling of brain oscillations may contribute to expanding our understanding of the neural processes underlying motivation and emotion.

  18. Water-absorbing capacitor system for measuring relative humidity

    NASA Technical Reports Server (NTRS)

    Laue, Eric G. (Inventor)

    1987-01-01

    A method and apparatus using a known water-absorbent polymer as a capacitor which is operated at a dc voltage for measuring relative humidity is presented. When formed as a layer between porous electrically-conductive electrodes and operated in an RC oscillator circuit, the oscillator frequency varies inversely with the partial pressure of the moisture to be measured. In a preferred embodiment, the capacitor is formed from Nafion and is operated at a low dc voltage with a resistor as an RC circuit in an RC oscillator. At the low voltage, the leakage current is proper for oscillation over a satisfactory range. The frequency of oscillation varies in an essentially linear fashion with relative humidity which is represented by the moisture being absorbed into the Nafion. The oscillation frequency is detected by a frequency detector.

  19. Spectral Analysis of Vibrational Harmonic Motion by use of a Continuous-Wave CO2 Doppler Lidar

    NASA Technical Reports Server (NTRS)

    Jarzembski, Maurice A.; Srivastava, Vandana

    1999-01-01

    Vibrational motion of a harmonic oscillator was investigated using a focused continuous wave CO2 Doppler lidar at 9.1 microns wavelength. A continuum of frequencies along with many discrete, equally spaced, resonant frequency modes was observed. The frequency modes are similar in structure to the oscillatory longitudinal modes of a laser cavity and arise because of interference of the natural resonant frequency of the oscillator with specific frequencies within the continuum. The spectra revealed departures from linear motion for vigorous vibrations of the oscillator. Each consecutive resonant frequency mode occurred for a movement of the oscillator much less than the wavelength of incident lidar radiation.

  20. A dynamical systems approach for estimating phase interactions between rhythms of different frequencies from experimental data.

    PubMed

    Onojima, Takayuki; Goto, Takahiro; Mizuhara, Hiroaki; Aoyagi, Toshio

    2018-01-01

    Synchronization of neural oscillations as a mechanism of brain function is attracting increasing attention. Neural oscillation is a rhythmic neural activity that can be easily observed by noninvasive electroencephalography (EEG). Neural oscillations show the same frequency and cross-frequency synchronization for various cognitive and perceptual functions. However, it is unclear how this neural synchronization is achieved by a dynamical system. If neural oscillations are weakly coupled oscillators, the dynamics of neural synchronization can be described theoretically using a phase oscillator model. We propose an estimation method to identify the phase oscillator model from real data of cross-frequency synchronized activities. The proposed method can estimate the coupling function governing the properties of synchronization. Furthermore, we examine the reliability of the proposed method using time-series data obtained from numerical simulation and an electronic circuit experiment, and show that our method can estimate the coupling function correctly. Finally, we estimate the coupling function between EEG oscillation and the speech sound envelope, and discuss the validity of these results.

  1. SOLAR-LIKE OSCILLATIONS IN LOW-LUMINOSITY RED GIANTS: FIRST RESULTS FROM KEPLER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bedding, T. R.; Huber, D.; Stello, D.

    2010-04-20

    We have measured solar-like oscillations in red giants using time-series photometry from the first 34 days of science operations of the Kepler Mission. The light curves, obtained with 30 minute sampling, reveal clear oscillations in a large sample of G and K giants, extending in luminosity from the red clump down to the bottom of the giant branch. We confirm a strong correlation between the large separation of the oscillations ({delta}{nu}) and the frequency of maximum power ({nu}{sub max}). We focus on a sample of 50 low-luminosity stars ({nu}{sub max} > 100 {mu}Hz, L {approx}< 30 L {sub sun}) havingmore » high signal-to-noise ratios and showing the unambiguous signature of solar-like oscillations. These are H-shell-burning stars, whose oscillations should be valuable for testing models of stellar evolution and for constraining the star formation rate in the local disk. We use a new technique to compare stars on a single echelle diagram by scaling their frequencies and find well-defined ridges corresponding to radial and non-radial oscillations, including clear evidence for modes with angular degree l = 3. Measuring the small separation between l = 0 and l = 2 allows us to plot the so-called C-D diagram of {delta}{nu}{sub 02} versus {delta}{nu}. The small separation {delta}{nu}{sub 01} of l = 1 from the midpoint of adjacent l = 0 modes is negative, contrary to the Sun and solar-type stars. The ridge for l = 1 is notably broadened, which we attribute to mixed modes, confirming theoretical predictions for low-luminosity giants. Overall, the results demonstrate the tremendous potential of Kepler data for asteroseismology of red giants.« less

  2. Nanoconstriction spin-Hall oscillator with perpendicular magnetic anisotropy

    NASA Astrophysics Data System (ADS)

    Divinskiy, B.; Demidov, V. E.; Kozhanov, A.; Rinkevich, A. B.; Demokritov, S. O.; Urazhdin, S.

    2017-07-01

    We experimentally study spin-Hall nano-oscillators based on [Co/Ni] multilayers with perpendicular magnetic anisotropy. We show that these devices exhibit single-frequency auto-oscillations at current densities comparable to those for in-plane magnetized oscillators. The demonstrated oscillators exhibit large magnetization precession amplitudes, and their oscillation frequency is highly tunable by the electric current. These features make them promising for applications in high-speed integrated microwave circuits.

  3. Different responses of spontaneous and stimulus-related alpha activity to ambient luminance changes.

    PubMed

    Benedetto, Alessandro; Lozano-Soldevilla, Diego; VanRullen, Rufin

    2017-12-04

    Alpha oscillations are particularly important in determining our percepts and have been implicated in fundamental brain functions. Oscillatory activity can be spontaneous or stimulus-related. Furthermore, stimulus-related responses can be phase- or non-phase-locked to the stimulus. Non-phase-locked (induced) activity can be identified as the average amplitude changes in response to a stimulation, while phase-locked activity can be measured via reverse-correlation techniques (echo function). However, the mechanisms and the functional roles of these oscillations are far from clear. Here, we investigated the effect of ambient luminance changes, known to dramatically modulate neural oscillations, on spontaneous and stimulus-related alpha. We investigated the effect of ambient luminance on EEG alpha during spontaneous human brain activity at rest (experiment 1) and during visual stimulation (experiment 2). Results show that spontaneous alpha amplitude increased by decreasing ambient luminance, while alpha frequency remained unaffected. In the second experiment, we found that under low-luminance viewing, the stimulus-related alpha amplitude was lower, and its frequency was slightly faster. These effects were evident in the phase-locked part of the alpha response (echo function), but weaker or absent in the induced (non-phase-locked) alpha responses. Finally, we explored the possible behavioural correlates of these modulations in a monocular critical flicker frequency task (experiment 3), finding that dark adaptation in the left eye decreased the temporal threshold of the right eye. Overall, we found that ambient luminance changes impact differently on spontaneous and stimulus-related alpha expression. We suggest that stimulus-related alpha activity is crucial in determining human temporal segmentation abilities. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  4. Temporal structure of neuronal population oscillations with empirical model decomposition

    NASA Astrophysics Data System (ADS)

    Li, Xiaoli

    2006-08-01

    Frequency analysis of neuronal oscillation is very important for understanding the neural information processing and mechanism of disorder in the brain. This Letter addresses a new method to analyze the neuronal population oscillations with empirical mode decomposition (EMD). Following EMD of neuronal oscillation, a series of intrinsic mode functions (IMFs) are obtained, then Hilbert transform of IMFs can be used to extract the instantaneous time frequency structure of neuronal oscillation. The method is applied to analyze the neuronal oscillation in the hippocampus of epileptic rats in vivo, the results show the neuronal oscillations have different descriptions during the pre-ictal, seizure onset and ictal periods of the epileptic EEG at the different frequency band. This new method is very helpful to provide a view for the temporal structure of neural oscillation.

  5. Implantable, Ingestible Electronic Thermometer

    NASA Technical Reports Server (NTRS)

    Kleinberg, Leonard

    1987-01-01

    Small quartz-crystal-controlled oscillator swallowed or surgically implanted provides continuous monitoring of patient's internal temperature. Receiver placed near patient measures oscillator frequency, and temperature inferred from previously determined variation of frequency with temperature. Frequency of crystal-controlled oscillator varies with temperature. Circuit made very small and implanted or ingested to measure internal body temperature.

  6. Effect of section shape on frequencies of natural oscillations of tubular springs

    NASA Astrophysics Data System (ADS)

    Pirogov, S. P.; Chuba, A. Yu; Cherentsov, D. A.

    2018-05-01

    The necessity of determining the frequencies of natural oscillations of manometric tubular springs is substantiated. Based on the mathematical model and computer program, numerical experiments were performed that allowed us to reveal the effect of geometric parameters on the frequencies of free oscillations of manometric tubular springs.

  7. Forced Longitudinal Oscillations of a Gas in an Open Pipe Near the Resonance Excitation Frequency

    NASA Astrophysics Data System (ADS)

    Zaripov, R. G.; Tkachenko, L. A.; Shaidullin, L. R.

    2017-11-01

    Results of theoretical and experimental investigations of forced longitudinal oscillations of a homogeneous gas in an open pipe near the first natural frequency are presented. It has been established that at the resonance frequency the shape of the gas pressure wave changes with time by a law different from the harmonic one. The amplitude-frequency characteristics of the indicated oscillations have been derived. Satisfactory agreement of the theoretical calculation of the gas pressure oscillation range with experimental data has been obtained.

  8. Analysis of Power System Low Frequency Oscillation Based on Energy Shift Theory

    NASA Astrophysics Data System (ADS)

    Zhang, Junfeng; Zhang, Chunwang; Ma, Daqing

    2018-01-01

    In this paper, a new method for analyzing low-frequency oscillation between analytic areas based on energy coefficient is proposed. The concept of energy coefficient is proposed by constructing the energy function, and the low-frequency oscillation is analyzed according to the energy coefficient under the current operating conditions; meanwhile, the concept of model energy is proposed to analyze the energy exchange behavior between two generators. Not only does this method provide an explanation of low-frequency oscillation from the energy point of view, but also it helps further reveal the dynamic behavior of complex power systems. The case analysis of four-machine two-area and the power system of Jilin Power Grid proves the correctness and effectiveness of the proposed method in low-frequency oscillation analysis of power system.

  9. A Novel Photonic Clock and Carrier Recovery Device

    NASA Technical Reports Server (NTRS)

    Yao, X. Steve; Lutes, George; Maleki, Lute

    1996-01-01

    As data communication rates climb toward ten Gb/s, clock recovery and synchronization become more difficult, if not impossible, using conventional electronic circuits. We present in this article experimental results of a high speed clock and carrier recovery using a novel device called a photonic oscillator that we recently developed in our laboratory. This device is capable of recovering clock signals up to 70 GHz. To recover the clock, the incoming data is injected into the photonic oscillator either through the optical injection port or the electrical injection port. The free running photonic oscillator is tuned to oscillate at a nominal frequency equal to the clock frequency of the incoming data. With the injection of the data, the photonic oscillator will be quickly locked to clock frequency of the data stream while rejecting other frequency components associated with the data. Consequently, the output of the locked photonic oscillator is a continuous periodical wave synchronized with the incoming data or simply the recovered clock. We have demonstrated a clock to spur ratio of more than 60 dB of the recovered clock using this technique. Similar to the clock recovery, the photonic oscillator can be used to recover a high frequency carrier degraded by noise and an improvement of about 50 dB in signal-to-noise ratio was demonstrated. The photonic oscillator has both electrical and optical inputs and outputs and can be directly interfaced with a photonic system without signal conversion. In addition to clock and carrier recovery, the photonic oscillator can also be used for (1) stable high frequency clock signal generation, (2) frequency multiplication, (3) square wave and comb frequency generation, and (4) photonic phase locked loop.

  10. The effects of ion channel blockers validate the conductance-based model of saccadic oscillations.

    PubMed

    Shaikh, Aasef G; Zee, David S; Optican, Lance M; Miura, Kenichiro; Ramat, Stefano; Leigh, R John

    2011-09-01

    Conductance-based models of reciprocally inhibiting burst neurons suggest that intrinsic membrane properties and postinhibitory rebound (PIR) determine the amplitude and frequency of saccadic oscillations. Reduction of the low-threshold calcium currents (I(T)) in the model decreased the amplitude but increased the frequency of the simulated oscillations. Combined reduction of hyperpolarization-activated cation current (I(h)) and I(T) in the model abolished the simulated oscillations. We measured the effects of a selective blocker of I(T) (ethosuximide) in healthy subjects on the amplitude and frequency of saccadic oscillations evoked by eye closure and of a nonselective blocker of I(h) and I(T) (propronolol) in a patient with microsaccadic oscillation and limb tremor syndrome (mSOLT). Ethosuximide significantly reduced the amplitude but increased the frequency of the saccadic oscillations during eye closure in healthy subjects. Propranolol abolished saccadic oscillations in the mSOLT patient. These results support the hypothetical role of postinhibitory rebound, I(h), and I(T) , in generation of saccadic oscillations and determining their kinematic properties. © 2011 New York Academy of Sciences.

  11. Electro-opto-mechanical radio-frequency oscillator driven by guided acoustic waves in standard single-mode fiber

    NASA Astrophysics Data System (ADS)

    London, Yosef; Diamandi, Hilel Hagai; Zadok, Avi

    2017-04-01

    An opto-electronic radio-frequency oscillator that is based on forward scattering by the guided acoustic modes of a standard single-mode optical fiber is proposed and demonstrated. An optical pump wave is used to stimulate narrowband, resonant guided acoustic modes, which introduce phase modulation to a co-propagating optical probe wave. The phase modulation is converted to an intensity signal at the output of a Sagnac interferometer loop. The intensity waveform is detected, amplified, and driven back to modulate the optical pump. Oscillations are achieved at a frequency of 319 MHz, which matches the resonance of the acoustic mode that provides the largest phase modulation of the probe wave. Oscillations at the frequencies of competing acoustic modes are suppressed by at least 40 dB. The linewidth of the acoustic resonance is sufficiently narrow to provide oscillations at a single longitudinal mode of the hybrid cavity. Competing longitudinal modes are suppressed by at least 38 dB as well. Unlike other opto-electronic oscillators, no radio-frequency filtering is required within the hybrid cavity. The frequency of oscillations is entirely determined by the fiber opto-mechanics.

  12. Atomic fountain clock with very high frequency stability employing a pulse-tube-cryocooled sapphire oscillator.

    PubMed

    Takamizawa, Akifumi; Yanagimachi, Shinya; Tanabe, Takehiko; Hagimoto, Ken; Hirano, Iku; Watabe, Ken-ichi; Ikegami, Takeshi; Hartnett, John G

    2014-09-01

    The frequency stability of an atomic fountain clock was significantly improved by employing an ultra-stable local oscillator and increasing the number of atoms detected after the Ramsey interrogation, resulting in a measured Allan deviation of 8.3 × 10(-14)τ(-1/2)). A cryogenic sapphire oscillator using an ultra-low-vibration pulse-tube cryocooler and cryostat, without the need for refilling with liquid helium, was applied as a local oscillator and a frequency reference. High atom number was achieved by the high power of the cooling laser beams and optical pumping to the Zeeman sublevel m(F) = 0 employed for a frequency measurement, although vapor-loaded optical molasses with the simple (001) configuration was used for the atomic fountain clock. The resulting stability is not limited by the Dick effect as it is when a BVA quartz oscillator is used as the local oscillator. The stability reached the quantum projection noise limit to within 11%. Using a combination of a cryocooled sapphire oscillator and techniques to enhance the atom number, the frequency stability of any atomic fountain clock, already established as primary frequency standard, may be improved without opening its vacuum chamber.

  13. Periodic forcing of a shock train in a scramjet inlet-isolator at overspeed condition

    NASA Astrophysics Data System (ADS)

    Jiao, Xiaoliang; Chang, Juntao; Wang, Zhongqi; Yu, Daren

    2018-02-01

    Unsteady viscous numerical simulations are performed to explore the response of a shock train to downstream backpressure forcing in a scramjet inlet-isolator at the overspeed condition. A sinusoidal dynamic backpressure is applied at the exit of the isolator, thus leading a forced shock train oscillation. The results show that the shock train travels along a different path for the upstream and downstream movements. There is a clear hysteresis loop during the shock train oscillation. Under the low forcing frequency, the shock train travels in a clockwise loop. While it travels in a counter-clockwise loop under the high forcing frequency. Moreover, there is a lag between the shock train oscillation and the fluctuating backpressure. Especially for the high forcing frequency, the phase of the shock train oscillation is opposite to the fluctuating backpressure. The effects of the amplitude and frequency of the periodic fluctuating backpressure on the oscillation range of the shock train are also investigated. With the amplitude of the fluctuating backpressure increasing, the oscillation range of the shock train increases. With the frequency of the fluctuating backpressure increasing, the oscillation range of the shock train increases first and then decreases under high frequency.

  14. Design considerations of Miller oscillators for high-sensitivity QCM sensors in damping media.

    PubMed

    Rodriguez-Pardo, Loreto; Fariña, Jose; Gabrielli, Claude; Perrot, Hubert; Brendel, Remi

    2007-10-01

    In this paper, a new contribution to the design of quartz crystal oscillators for high-sensitivity microbalance sensors used in liquid media is presented. The oscillation condition for a Miller configuration was studied to work in a wide dynamic range of the resonator losses. The equations relating the values of the active and passive components with the maximum supported damping and mass were obtained. Also, the conditions to obtain a stable frequency according to the resonator damping (R(Q)), the static capacity (Cp) and the filter frequency (f(F)) were found. Under these conditions, the circuit oscillation frequency will be proportional to the resonant series frequency and does not depend on the previous parameters (R(Q), f(F), and Cp). If these conditions cannot be satisfied, the expression of the oscillation frequency is given and the discrimination of these effects is obtained through resonator frequency measurements.

  15. High-frequency resonant-tunneling oscillators

    NASA Technical Reports Server (NTRS)

    Brown, E. R.; Parker, C. D.; Calawa, A. R.; Manfra, M. J.; Chen, C. L.

    1991-01-01

    Advances in high-frequency resonant-tunneling-diode (RTD) oscillators are described. Oscillations up to a frequency of 420 GHz have been achieved in the GaAs/AlAs system. Recent results obtained with In0.53Ga0.47As/AlAs and InAs/AlSb RTDs show a greatly increased power density and indicate the potential for fundamental oscillations up to about 1 THz. These results are consistent with a lumped-element equivalent circuit model of the RTD. The model shows that the maximum oscillation frequency of the GaAs/AlAs RTDs is limited primarily by series resistance, and that the power density is limited by low peak-to-valley current ratio.

  16. Adaptive Injection-locking Oscillator Array for RF Spectrum Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leung, Daniel

    2011-04-19

    A highly parallel radio frequency receiver using an array of injection-locking oscillators for on-chip, rapid estimation of signal amplitudes and frequencies is considered. The oscillators are tuned to different natural frequencies, and variable gain amplifiers are used to provide negative feedback to adapt the locking band-width with the input signal to yield a combined measure of input signal amplitude and frequency detuning. To further this effort, an array of 16 two-stage differential ring oscillators and 16 Gilbert-cell mixers is designed for 40-400 MHz operation. The injection-locking oscillator array is assembled on a custom printed-circuit board. Control and calibration is achievedmore » by on-board microcontroller.« less

  17. Relationship between oscillatory neuronal activity during reward processing and trait impulsivity and sensation seeking.

    PubMed

    Leicht, Gregor; Troschütz, Stefan; Andreou, Christina; Karamatskos, Evangelos; Ertl, Matthias; Naber, Dieter; Mulert, Christoph

    2013-01-01

    The processing of reward and punishment stimuli in humans appears to involve brain oscillatory activity of several frequencies, probably each with a distinct function. The exact nature of associations of these electrophysiological measures with impulsive or risk-seeking personality traits is not completely clear. Thus, the aim of the present study was to investigate event-related oscillatory activity during reward processing across a wide spectrum of frequencies, and its associations with impulsivity and sensation seeking in healthy subjects. During recording of a 32-channel EEG 22 healthy volunteers were characterized with the Barratt Impulsiveness and the Sensation Seeking Scale and performed a computerized two-choice gambling task comprising different feedback options with positive vs. negative valence (gain or loss) and high or low magnitude (5 vs. 25 points). We observed greater increases of amplitudes of the feedback-related negativity and of activity in the theta, alpha and low-beta frequency range following loss feedback and, in contrast, greater increase of activity in the high-beta frequency range following gain feedback. Significant magnitude effects were observed for theta and delta oscillations, indicating greater amplitudes upon feedback concerning large stakes. The theta amplitude changes during loss were negatively correlated with motor impulsivity scores, whereas alpha and low-beta increase upon loss and high-beta increase upon gain were positively correlated with various dimensions of sensation seeking. The findings suggest that the processing of feedback information involves several distinct processes, which are subserved by oscillations of different frequencies and are associated with different personality traits.

  18. Surface oscillation of levitated liquid droplets under microgravity

    NASA Astrophysics Data System (ADS)

    Watanabe, Masahito; Hibiya, Taketoshi; Ozawa, Shumpei; Mizuno, Akitoshi

    2012-07-01

    Microgravity conditions have advantages of measurement of surface tension and viscosity of metallic liquids by the oscillating drop method with an electromagnetic levitation (EML) device. Thus, we are now planning the thermophysical properties, the surface tension, viscosity, density and etc., measurements of liquid alloys using the electromagnetic levitator named MSL-EML (Materials Science Laboratory Electromagnetic Levitator), which ahs been developed by the European Space Agency (ESA), installed in the International Space Station (ISS). The surface tension and the viscosity of liquid samples by the oscillating drop method are obtained from the surface oscillation frequency and damping time of surface oscillation respectively. However, analysis of oscillating drop method in EML must be improved even in the microgravity conditions, because on the EML conditions the electromagnetic force (EMF) cannot generate the surface oscillation with discretely oscillation mode. Since under microgravity the levitated droplet shape is completely spherical, the surface oscillation frequency with different oscillation modes degenerates into the single frequency. Therefore, surface tension will be not affected the EML condition under microgravity, but viscosity will be affected on the different oscillation mode of surface oscillations. Because dumping time of surface oscillation of liquid droplets depends on the oscillation modes, the case of surface oscillation including multi oscillation modes the viscosity values obtained from dumping time will be modified from the correct viscosity. Therefore, we investigate the dumping time of surface oscillation of levitated droplets with different oscillation modes and also with including multi oscillation modes using the electrostatic levitation (ESL) on ground and EML under microgravity conditions by the parabolic flight of airplane. The ESL can discretely generate the surface oscillation with different oscillation modes by the change of generation frequency of surface oscillation, so we can obtain dumping time of surface oscillation with discrete oscillation mode. We repot the results of the damping time of the surface oscillation of levitated liquid droplet by ESL and EML experiment with numerical simulation of the damped oscillation model.

  19. Weld pool oscillation during GTA welding of mild steel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiao, Y.H.; Ouden, G. den

    1993-08-01

    In this paper the results are reported of a study dealing with the oscillation behavior of weld pools in the case of GTA bead-on-plate welding of mild steel, Fe 360. During welding, the weld pool was brought into oscillation by applying short current pulses, and the oscillation frequency and amplitude were measured by monitoring the arc voltage. It was found that the oscillation of the partially penetrated weld pool is dominated by one of two different oscillation modes (Mode 1 and Mode 2) depending on the welding conditions, whereas the oscillation of the fully penetrated weld pool is characterized bymore » a third oscillation mode (Mode 3). It is possible to maintain partially penetrated weld pool oscillation in Mode 1 by choosing appropriate welding conditions. Under these conditions, an abrupt decrease in oscillation frequency occurs when the weld pool transfers from partial penetration to full penetration. Thus, weld penetration can be in-process controlled by monitoring the oscillation frequency during welding.« less

  20. Exciton absorption of entangled photons in semiconductor quantum wells

    NASA Astrophysics Data System (ADS)

    Rodriguez, Ferney; Guzman, David; Salazar, Luis; Quiroga, Luis; Condensed Matter Physics Group Team

    2013-03-01

    The dependence of the excitonic two-photon absorption on the quantum correlations (entanglement) of exciting biphotons by a semiconductor quantum well is studied. We show that entangled photon absorption can display very unusual features depending on space-time-polarization biphoton parameters and absorber density of states for both bound exciton states as well as for unbound electron-hole pairs. We report on the connection between biphoton entanglement, as quantified by the Schmidt number, and absorption by a semiconductor quantum well. Comparison between frequency-anti-correlated, unentangled and frequency-correlated biphoton absorption is addressed. We found that exciton oscillator strengths are highly increased when photons arrive almost simultaneously in an entangled state. Two-photon-absorption becomes a highly sensitive probe of photon quantum correlations when narrow semiconductor quantum wells are used as two-photon absorbers. Research funds from Facultad de Ciencias, Universidad de los Andes

  1. Recent Developments in the Analysis of Couple Oscillator Arrays

    NASA Technical Reports Server (NTRS)

    Pogorzelski, Ronald J.

    2000-01-01

    This presentation considers linear arrays of coupled oscillators. Our purpose in coupling oscillators together is to achieve high radiated power through the spatial power combining which results when the oscillators are injection locked to each other. York, et. al. have shown that, left to themselves, the ensemble of injection locked oscillators oscillate at the average of the tuning frequencies of all the oscillators. Coupling these arrays achieves high radiated power through coherent spatial power combining. The coupled oscillators are usually designed to produce constant aperture phase. Oscillators are injection locked to each other or to a master oscillator to produce coherent radiation. Oscillators do not necessarily oscillate at their tuning frequency.

  2. Dynamics of a spin-boson model with structured spectral density

    NASA Astrophysics Data System (ADS)

    Kurt, Arzu; Eryigit, Resul

    2018-05-01

    We report the results of a study of the dynamics of a two-state system coupled to an environment with peaked spectral density. An exact analytical expression for the bath correlation function is obtained. Validity range of various approximations to the correlation function for calculating the population difference of the system is discussed as function of tunneling splitting, oscillator frequency, coupling constant, damping rate and the temperature of the bath. An exact expression for the population difference, for a limited range of parameters, is derived.

  3. Subthalamic Synchronized Oscillatory Activity Correlates With Motor Impairment in Patients With Parkinson’s Disease

    PubMed Central

    Neumann, Wolf-Julian; Degen, Katharina; Schneider, Gerd-Helge; Brücke, Christof; Huebl, Julius; Brown, Peter; Kühn, Andrea A.

    2016-01-01

    Objective Beta band oscillations in the subthalamic nucleus (STN) have been proposed as a pathophysiological signature in patients with Parkinson’s disease (PD). The aim of this study was to investigate the potential association between oscillatory activity in the STN and symptom severity in PD. Methods Subthalamic local field potentials were recorded from 63 PD patients in a dopaminergic OFF state. Power-spectra were analyzed for the frequency range from 5 to 95 Hz and correlated with individual UPDRS-III motor scores in the OFF state. Results A correlation between total UPDRS-III scores and 8 to 35 Hz activity was revealed across all patients (ρ = 0.44, P <.0001). When correlating each frequency bin, a narrow range from 10 to 15 Hz remained significant for the correlation (false discovery rate corrected P <.05). Conclusion Our results show a correlation between local STN 8 to 35 Hz power and impairment in PD, further supporting the role of subthalamic oscillatory activity as a potential biomarker for PD. PMID:27548068

  4. Ketamine-Induced Oscillations in the Motor Circuit of the Rat Basal Ganglia

    PubMed Central

    Alegre, Manuel; Pérez-Alcázar, Marta; Iriarte, Jorge; Artieda, Julio

    2011-01-01

    Oscillatory activity can be widely recorded in the cortex and basal ganglia. This activity may play a role not only in the physiology of movement, perception and cognition, but also in the pathophysiology of psychiatric and neurological diseases like schizophrenia or Parkinson's disease. Ketamine administration has been shown to cause an increase in gamma activity in cortical and subcortical structures, and an increase in 150 Hz oscillations in the nucleus accumbens in healthy rats, together with hyperlocomotion. We recorded local field potentials from motor cortex, caudate-putamen (CPU), substantia nigra pars reticulata (SNr) and subthalamic nucleus (STN) in 20 awake rats before and after the administration of ketamine at three different subanesthetic doses (10, 25 and 50 mg/Kg), and saline as control condition. Motor behavior was semiautomatically quantified by custom-made software specifically developed for this setting. Ketamine induced coherent oscillations in low gamma (50 Hz), high gamma (80 Hz) and high frequency (HFO, 150 Hz) bands, with different behavior in the four structures studied. While oscillatory activity at these three peaks was widespread across all structures, interactions showed a different pattern for each frequency band. Imaginary coherence at 150 Hz was maximum between motor cortex and the different basal ganglia nuclei, while low gamma coherence connected motor cortex with CPU and high gamma coherence was more constrained to the basal ganglia nuclei. Power at three bands correlated with the motor activity of the animal, but only coherence values in the HFO and high gamma range correlated with movement. Interactions in the low gamma band did not show a direct relationship to movement. These results suggest that the motor effects of ketamine administration may be primarily mediated by the induction of coherent widespread high-frequency activity in the motor circuit of the basal ganglia, together with a frequency-specific pattern of connectivity among the structures analyzed. PMID:21829443

  5. Dose-response relationship of autonomic nervous system responses to individualized training impulse in marathon runners.

    PubMed

    Manzi, Vincenzo; Castagna, Carlo; Padua, Elvira; Lombardo, Mauro; D'Ottavio, Stefano; Massaro, Michele; Volterrani, Maurizio; Iellamo, Ferdinando

    2009-06-01

    In athletes, exercise training induces autonomic nervous system (ANS) adaptations that could be used to monitor training status. However, the relationship between training and ANS in athletes has been investigated without regard for individual training loads. We tested the hypothesis that in long-distance athletes, changes in ANS parameters are dose-response related to individual volume/intensity training load and could predict athletic performance. A spectral analysis of heart rate (HR), systolic arterial pressure variability, and baroreflex sensitivity by the sequences technique was investigated in eight recreational athletes during a 6-mo training period culminating with a marathon. Individualized training load responses were monitored by a modified training impulse (TRIMP(i)) method, which was determined in each athlete using the individual HR and lactate profiling determined during a treadmill test. Monthly TRIMP(i) steadily increased during the training period. All the ANS parameters were significantly and very highly correlated to the dose of exercise with a second-order regression model (r(2) ranged from 0.90 to 0.99; P < 0.001). Variance, high-frequency oscillations of HR variability (HRV), and baroreflex sensitivity resembled a bell-shaped curve with a minimum at the highest TRIMP(i), whereas low-frequency oscillations of HR and systolic arterial pressure variability and the low frequency (LF)-to-high frequency ratio resembled an U-shaped curve with a maximum at the highest TRIMP(i). The LF component of HRV assessed at the last recording session was significantly and inversely correlated to the time needed to complete the nearing marathon. These results suggest that in recreational athletes, ANS adaptations to exercise training are dose related on an individual basis, showing a progressive shift toward a sympathetic predominance, and that LF oscillations in HRV at peak training load could predict athletic achievement in this athlete population.

  6. Random perturbations of a periodically driven nonlinear oscillator: escape from a resonance zone

    NASA Astrophysics Data System (ADS)

    Lingala, Nishanth; Sri Namachchivaya, N.; Pavlyukevich, Ilya

    2017-04-01

    For nonlinear oscillators, frequency of oscillations depends on the oscillation amplitude. When a nonlinear oscillator is periodically driven, the phase space consists of many resonance zones where the oscillator frequency and the driving frequency are commensurable. It is well known that, a small subset of initial conditions can lead to capture in one of the resonance zones. In this paper we study the effect of weak noise on the escape from a resonance zone. Using averaging techniques we obtain the mean exit time from a resonance zone and study the dependence of the exit rate on the parameters of the oscillator. Paper dedicated to Professor Peter W Sauer of University of Illinois on the occasion of his 70th birthday.

  7. High Speed Laser with 100 Ghz Resonance Frequency

    DTIC Science & Technology

    2014-02-28

    applications, such as opto - electronic oscillators . Recently, however, by optimizing the detuning frequency and injection ratio, we have shown enhanced...semiconductor lasers has been limited by relaxation oscillation frequency to < 40 GHz. By using strong optical injection locking, we report resonance...direct modulation bandwidth of semiconductor lasers. In a typical laser, the relaxation oscillation [resonance] frequency is a figure-of-merit that is a

  8. Effects Of Local Oscillator Errors On Digital Beamforming

    DTIC Science & Technology

    2016-03-01

    processor EF element factor EW electronic warfare FFM flicker frequency modulation FOV field-of-view FPGA field-programmable gate array FPM flicker...frequencies and also more difficult to measure [15]. 2. Flicker frequency modulation The source for flicker frequency modulation ( FFM ) is attributed to...a physical resonance mechanism of an oscillator or issues controlling electronic components. Some oscillators might not show FFM noise, which might

  9. Duffing revisited: phase-shift control and internal resonance in self-sustained oscillators

    NASA Astrophysics Data System (ADS)

    Arroyo, Sebastián I.; Zanette, Damián H.

    2016-01-01

    We address two aspects of the dynamics of the forced Duffing oscillator which are relevant to the technology of micromechanical devices and, at the same time, have intrinsic significance to the field of nonlinear oscillating systems. First, we study the stability of periodic motion when the phase shift between the external force and the oscillation is controlled - contrary to the standard case, where the control parameter is the frequency of the force. Phase-shift control is the operational configuration under which self-sustained oscillators - and, in particular, micromechanical oscillators - provide a frequency reference useful for time keeping. We show that, contrary to the standard forced Duffing oscillator, under phase-shift control oscillations are stable over the whole resonance curve, and provide analytical approximate expressions for the time dependence of the oscillation amplitude and frequency during transients. Second, we analyze a model for the internal resonance between the main Duffing oscillation mode and a higher-harmonic mode of a vibrating solid bar clamped at its two ends. We focus on the stabilization of the oscillation frequency when the resonance takes place, and present preliminary experimental results that illustrate the phenomenon. This synchronization process has been proposed to counteract the undesirable frequency-amplitude interdependence in nonlinear time-keeping micromechanical devices. Supplementary material in the form of one pdf file and one gif file available from the Journal web page at http://dx.doi.org/10.1140/epjb/e2015-60517-3

  10. Spontaneous ripples in the hippocampus correlate with epileptogenicity and not memory function in patients with refractory epilepsy.

    PubMed

    Jacobs, Julia; Banks, Sarah; Zelmann, Rina; Zijlmans, Maeike; Jones-Gotman, Marilyn; Gotman, Jean

    2016-09-01

    High-frequency oscillations (HFOs, 80-500Hz) are newly-described EEG markers of epileptogenicity. The proportion of physiological and pathological HFOs is unclear, as frequency analysis is insufficient for separating the two types of events. For instance, ripples (80-250Hz) also occur physiologically during memory consolidation processes in medial temporal lobe structures. We investigated the correlation between HFO rates and memory performance. Patients investigated with bilateral medial temporal electrodes and an intellectual capacity allowing for memory testing were included. High-frequency oscillations were visually marked, and rates of HFOs were calculated for each channel during slow-wave sleep. Patients underwent three verbal and three nonverbal memory tests. They were grouped into severe impairment, some impairment, mostly intact, or intact for verbal and nonverbal memory. We calculated a Pearson correlation between HFO rates in the hippocampi and the memory category and compared HFO rates in each hippocampus with the corresponding (verbal - left, nonverbal - right) memory result using Wilcoxon rank-sum test. Twenty patients were included; ten had bilateral, five had unilateral, and five had no memory impairment. Unilateral memory impairment was verbal in one patient and nonverbal in four. There was no correlation between HFO rates and memory performance in seizure onset areas. There was, however, a significant negative correlation between the overall memory performance and ripple rates (r=-0.50, p=0.03) outside the seizure onset zone. Our results suggest that the majority of spontaneous hippocampal ripples, as defined in the present study, may reflect pathological activity, taking into account the association with memory impairment. The absence of negative correlation between memory performance and HFO rates in seizure onset areas could be explained by HFO rates in the SOZ being generally so high that differences between areas with remaining and impaired memory function cannot be seen. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. A finite state machine read-out chip for integrated surface acoustic wave sensors

    NASA Astrophysics Data System (ADS)

    Rakshit, Sambarta; Iliadis, Agis A.

    2015-01-01

    A finite state machine based integrated sensor circuit suitable for the read-out module of a monolithically integrated SAW sensor on Si is reported. The primary sensor closed loop consists of a voltage controlled oscillator (VCO), a peak detecting comparator, a finite state machine (FSM), and a monolithically integrated SAW sensor device. The output of the system oscillates within a narrow voltage range that correlates with the SAW pass-band response. The period of oscillation is of the order of the SAW phase delay. We use timing information from the FSM to convert SAW phase delay to an on-chip 10 bit digital output operating on the principle of time to digital conversion (TDC). The control inputs of this digital conversion block are generated by a second finite state machine operating under a divided system clock. The average output varies with changes in SAW center frequency, thus tracking mass sensing events in real time. Based on measured VCO gain of 16 MHz/V our system will convert a 10 kHz SAW frequency shift to a corresponding mean voltage shift of 0.7 mV. A corresponding shift in phase delay is converted to a one or two bit shift in the TDC output code. The system can handle alternate SAW center frequencies and group delays simply by adjusting the VCO control and TDC delay control inputs. Because of frequency to voltage and phase to digital conversion, this topology does not require external frequency counter setups and is uniquely suitable for full monolithic integration of autonomous sensor systems and tags.

  12. Somatic evoked high-frequency magnetic oscillations reflect activity of inhibitory interneurons in the human somatosensory cortex.

    PubMed

    Hashimoto, I; Mashiko, T; Imada, T

    1996-05-01

    High-frequency potential oscillations in the range of 300-900 Hz have recently been shown to concur with the primary response (N20) of the somatosensory cortex in awake humans. However, the physiological mechanisms of the high-frequency oscillations remained undetermined. We addressed the issue by analyzing magnetic fields during wakefulness and sleep over the left hemisphere to right median nerve stimulation with a wide bandpass (0.1-2000 Hz) recording with subsequent high-pass (> 300 Hz) and low-pass (< 300 Hz) filtering. With wide bandpass recordings, high-frequency magnetic oscillations with the main signal energy at 580-780 Hz were superimposed on the N20m during wakefulness. Isofield mapping at each peak of the high-pass filtered and isolated high-frequency oscillations showed a dipolar pattern and the estimated source for these peaks was the primary somatosensory cortex (area 3b) very close to that for the N20m peak. During sleep, the high-frequency oscillations showed dramatic diminution in amplitude while the N20m amplitude exhibited a moderate increment. This reciprocal relation between the high-frequency oscillations and the N20m during a wake-sleep cycle suggests that they represent different generator substrates. We speculate that the high-frequency oscillations represent a localized activity of the GABAergic inhibitory interneurons of layer 4, which have been shown in animal experiments to respond monosynaptically to thalamo-cortical input with a high-frequency (600-900 Hz) burst of short duration spikes. On the other hand, the underlying N20m represents activity of pyramidal neurons which receive monosynaptic excitatory input from the thalamus as well as a feed-forward inhibition from the interneurons.

  13. Changes in interhemispheric motor connectivity after muscle fatigue

    NASA Astrophysics Data System (ADS)

    Peltier, Scott; LaConte, Stephen M.; Niyazov, Dmitriy; Liu, Jing; Sahgal, Vinod; Yue, Guang; Hu, Xiaoping

    2005-04-01

    Synchronized oscillations in resting state timecourses have been detected in recent fMRI studies. These oscillations are low frequency in nature (< 0.08 Hz), and seem to be a property of symmetric cortices. These fluctuations are important as a potential signal of interest, which could indicate connectivity between functionally related areas of the brain. It has also been shown that the synchronized oscillations decrease in some spontaneous pathological states. Thus, detection of these functional connectivity patterns may help to serve as a gauge of normal brain activity. The cognitive effects of muscle fatigue are not well characterized. Sustained fatigue has the potential to dynamically alter activity in brain networks. In this work, we examined the interhemispheric correlations in the left and right primary motor cortices and how they change with muscle fatigue. Resting-state functional MRI imaging was done before and after a repetitive unilateral fatigue task. We find that the number of significant correlations in the bilateral motor network decreases with fatigue. These results suggest that resting-state interhemispheric motor cortex functional connectivity is affected by muscle fatigue.

  14. Abnormal functional integration of thalamic low frequency oscillation in the BOLD signal after acute heroin treatment.

    PubMed

    Denier, Niklaus; Schmidt, André; Gerber, Hana; Vogel, Marc; Huber, Christian G; Lang, Undine E; Riecher-Rossler, Anita; Wiesbeck, Gerhard A; Radue, Ernst-Wilhelm; Walter, Marc; Borgwardt, Stefan

    2015-12-01

    Heroin addiction is a severe relapsing brain disorder associated with impaired cognitive control, including deficits in attention allocation. The thalamus has a high density of opiate receptors and is critically involved in orchestrating cortical activity during cognitive control. However, there have been no studies on how acute heroin treatment modulates thalamic activity. In a cross-over, double-blind, vehicle-controlled study, 29 heroin-maintained outpatients were studied after heroin and placebo administration, while 20 healthy controls were included for the placebo condition only. Resting-state functional magnetic resonance imaging was used to analyze functional integration of the thalamus by three different resting state analysis techniques. Thalamocortical functional connectivity (FC) was analyzed by seed-based correlation, while intrinsic thalamic oscillation was assessed by analysis of regional homogeneity (ReHo) and the fractional amplitude of low frequency fluctuations (fALFF). Relative to the placebo treatment and healthy controls, acute heroin administration reduced thalamocortical FC to cortical regions, including the frontal cortex, while the reductions in FC to the mediofrontal cortex, orbitofrontal cortex, and frontal pole were positively correlated with the plasma level of morphine, the main psychoactive metabolite of heroin. Furthermore, heroin treatment was associated with increased thalamic ReHo and fALFF values, whereas fALFF following heroin exposure correlated negatively with scores of attentional control. The heroin-associated increase in fALFF was mainly dominated by slow-4 (0.027-0.073 Hz) oscillations. Our findings show that there are acute effects of heroin within the thalamocortical system and may shed new light on the role of the thalamus in cognitive control in heroin addiction. Future research is needed to determine the underlying physiological mechanisms and their role in heroin addiction. © 2015 Wiley Periodicals, Inc.

  15. Selective Coupling between Theta Phase and Neocortical Fast Gamma Oscillations during REM-Sleep in Mice

    PubMed Central

    Scheffzük, Claudia; Kukushka, Valeriy I.; Vyssotski, Alexei L.; Draguhn, Andreas

    2011-01-01

    Background The mammalian brain expresses a wide range of state-dependent network oscillations which vary in frequency and spatial extension. Such rhythms can entrain multiple neurons into coherent patterns of activity, consistent with a role in behaviour, cognition and memory formation. Recent evidence suggests that locally generated fast network oscillations can be systematically aligned to long-range slow oscillations. It is likely that such cross-frequency coupling supports specific tasks including behavioural choice and working memory. Principal Findings We analyzed temporal coupling between high-frequency oscillations and EEG theta activity (4–12 Hz) in recordings from mouse parietal neocortex. Theta was exclusively present during active wakefulness and REM-sleep. Fast oscillations occurred in two separate frequency bands: gamma (40–100 Hz) and fast gamma (120–160 Hz). Theta, gamma and fast gamma were more prominent during active wakefulness as compared to REM-sleep. Coupling between theta and the two types of fast oscillations, however, was more pronounced during REM-sleep. This state-dependent cross-frequency coupling was particularly strong for theta-fast gamma interaction which increased 9-fold during REM as compared to active wakefulness. Theta-gamma coupling increased only by 1.5-fold. Significance State-dependent cross-frequency-coupling provides a new functional characteristic of REM-sleep and establishes a unique property of neocortical fast gamma oscillations. Interactions between defined patterns of slow and fast network oscillations may serve selective functions in sleep-dependent information processing. PMID:22163023

  16. Effects of dendritic load on the firing frequency of oscillating neurons.

    PubMed

    Schwemmer, Michael A; Lewis, Timothy J

    2011-03-01

    We study the effects of passive dendritic properties on the dynamics of neuronal oscillators. We find that the addition of a passive dendrite can sometimes have counterintuitive effects on firing frequency. Specifically, the addition of a hyperpolarized passive dendritic load can either increase, decrease, or have negligible effects on firing frequency. We use the theory of weak coupling to derive phase equations for "ball-and-stick" model neurons and two-compartment model neurons. We then develop a framework for understanding how the addition of passive dendrites modulates the frequency of neuronal oscillators. We show that the average value of the neuronal oscillator's phase response curves measures the sensitivity of the neuron's firing rate to the dendritic load, including whether the addition of the dendrite causes an increase or decrease in firing frequency. We interpret this finding in terms of to the slope of the neuronal oscillator's frequency-applied current curve. We also show that equivalent results exist for constant and noisy point-source input to the dendrite. We note that the results are not specific to neurons but are applicable to any oscillator subject to a passive load.

  17. Nonlinearity induced synchronization enhancement in mechanical oscillators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Czaplewski, David A.; Lopez, Omar; Guest, Jeffrey R.

    An autonomous oscillator synchronizes to an external harmonic force only when the forcing frequency lies within a certain interval, known as the synchronization range, around the oscillator's natural frequency. Under ordinary conditions, the width of the synchronization range decreases when the oscillation amplitude grows, which constrains synchronized motion of micro- and nano-mechanical resonators to narrow frequency and amplitude bounds. The present invention shows that nonlinearity in the oscillator can be exploited to manifest a regime where the synchronization range increases with an increasing oscillation amplitude. The present invention shows that nonlinearities in specific configurations of oscillator systems, as described herein,more » are the key determinants of the effect. The present invention presents a new configuration and operation regime that enhances the synchronization of micro- and nano-mechanical oscillators by capitalizing on their intrinsic nonlinear dynamics.« less

  18. TESTING SCALING RELATIONS FOR SOLAR-LIKE OSCILLATIONS FROM THE MAIN SEQUENCE TO RED GIANTS USING KEPLER DATA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huber, D.; Bedding, T. R.; Stello, D.

    2011-12-20

    We have analyzed solar-like oscillations in {approx}1700 stars observed by the Kepler Mission, spanning from the main sequence to the red clump. Using evolutionary models, we test asteroseismic scaling relations for the frequency of maximum power ({nu}{sub max}), the large frequency separation ({Delta}{nu}), and oscillation amplitudes. We show that the difference of the {Delta}{nu}-{nu}{sub max} relation for unevolved and evolved stars can be explained by different distributions in effective temperature and stellar mass, in agreement with what is expected from scaling relations. For oscillation amplitudes, we show that neither (L/M){sup s} scaling nor the revised scaling relation by Kjeldsen andmore » Bedding is accurate for red-giant stars, and demonstrate that a revised scaling relation with a separate luminosity-mass dependence can be used to calculate amplitudes from the main sequence to red giants to a precision of {approx}25%. The residuals show an offset particularly for unevolved stars, suggesting that an additional physical dependency is necessary to fully reproduce the observed amplitudes. We investigate correlations between amplitudes and stellar activity, and find evidence that the effect of amplitude suppression is most pronounced for subgiant stars. Finally, we test the location of the cool edge of the instability strip in the Hertzsprung-Russell diagram using solar-like oscillations and find the detections in the hottest stars compatible with a domain of hybrid stochastically excited and opacity driven pulsation.« less

  19. Cardiovascular regulation in humans in response to oscillatory lower body negative pressure

    NASA Technical Reports Server (NTRS)

    Levenhagen, D. K.; Evans, J. M.; Wang, M.; Knapp, C. F.

    1994-01-01

    The frequency response characteristics of human cardiovascular regulation during hypotensive stress have not been determined. We therefore exposed 10 male volunteers to seven frequencies (0.004-0.1 Hz) of oscillatory lower body negative pressure (OLBNP; 0-50 mmHg). Fourier spectra of arterial pressure (AP), central venous pressure (CVP), stroke volume (SV), cardiac output (CO), heart rate (HR), and total peripheral resistance (TPR) were determined and first harmonic mean, amplitude, and phase angles with respect to OLBNP are presented. AP was relatively well regulated as demonstrated by small oscillations in half amplitude (3.5 mmHg) that were independent of OLBNP frequency and similar to unstressed control spectra. Due to the biomechanics of the system, the magnitudes of oscillations in calf circumference (CC) and CVP decreased with increasing frequency; therefore, we normalized responses by these indexes of the fluid volume shifted. The ratios of oscillations in AP to oscillations in CC increased by an order of magnitude, whereas oscillations in CVP to oscillations in CC and oscillations in AP to oscillations in CVP both tripled between 0.004 and 0.1 Hz. Therefore, even though the amount of fluid shifted by OLBNP decreased with increasing frequency, the magnitude of both CVP and AP oscillations per volume of fluid shifted increased (peaking at 0.08 Hz). The phase relationships between variables, particularly the increasing lags in SV and TPR, but not CVP, indicated that efferent responses with lags of 5-6 s could account for the observed responses. We conclude that, at frequencies below 0.02 Hz, the neural system of humans functioned optimally in regulating AP; OLBNP-induced decreases in SV (by as much as 50%) were counteracted by appropriate oscillations in HR and TPR responses. As OLBNP frequency increased, SV, TPR, and HR oscillations increasingly lagged the input and became less optimally timed for AP regulation.

  20. Optical parametric amplification and oscillation assisted by low-frequency stimulated emission.

    PubMed

    Longhi, Stefano

    2016-04-15

    Optical parametric amplification and oscillation provide powerful tools for coherent light generation in spectral regions inaccessible to lasers. Parametric gain is based on a frequency down-conversion process and, thus, it cannot be realized for signal waves at a frequency ω3 higher than the frequency of the pump wave ω1. In this Letter, we suggest a route toward the realization of upconversion optical parametric amplification and oscillation, i.e., amplification of the signal wave by a coherent pump wave of lower frequency, assisted by stimulated emission of the auxiliary idler wave. When the signal field is resonated in an optical cavity, parametric oscillation is obtained. Design parameters for the observation of upconversion optical parametric oscillation at λ3=465 nm are given for a periodically poled lithium-niobate (PPLN) crystal doped with Nd(3+) ions.

  1. Applications of surface acoustic and shallow bulk acoustic wave devices

    NASA Astrophysics Data System (ADS)

    Campbell, Colin K.

    1989-10-01

    Surface acoustic wave (SAW) device coverage includes delay lines and filters operating at selected frequencies in the range from about 10 MHz to 11 GHz; modeling with single-crystal piezoelectrics and layered structures; resonators and low-loss filters; comb filters and multiplexers; antenna duplexers; harmonic devices; chirp filters for pulse compression; coding with fixed and programmable transversal filters; Barker and quadraphase coding; adaptive filters; acoustic and acoustoelectric convolvers and correlators for radar, spread spectrum, and packet radio; acoustooptic processors for Bragg modulation and spectrum analysis; real-time Fourier-transform and cepstrum processors for radar and sonar; compressive receivers; Nyquist filters for microwave digital radio; clock-recovery filters for fiber communications; fixed-, tunable-, and multimode oscillators and frequency synthesizers; acoustic charge transport; and other SAW devices for signal processing on gallium arsenide. Shallow bulk acoustic wave device applications include gigahertz delay lines, surface-transverse-wave resonators employing energy-trapping gratings, and oscillators with enhanced performance and capability.

  2. Oscillations up to 712 GHz in InAs/AlSb resonant-tunneling diodes

    NASA Technical Reports Server (NTRS)

    Brown, E. R.; Parker, C. D.; Mahoney, L. J.; Molvar, K. M.; Soderstrom, J. R.

    1991-01-01

    Oscillations have been obtained at frequencies from 100 to 712 GHz in InAs/AlSb double-barrier resonant-tunneling diodes at room temperature. The measured power density at 360 GHz was 90 W/sq cm, which is 50 times that generated by GaAs/AlAs diodes at essentially the same frequency. The oscillation at 712 GHz represents the highest frequency reported to date from a solid-state electronic oscillator at room temperature.

  3. Network properties of interstitial cells of Cajal affect intestinal pacemaker activity and motor patterns, according to a mathematical model of weakly coupled oscillators.

    PubMed

    Wei, Ruihan; Parsons, Sean P; Huizinga, Jan D

    2017-03-01

    What is the central question of this study? What are the effects of interstitial cells of Cajal (ICC) network perturbations on intestinal pacemaker activity and motor patterns? What is the main finding and its importance? Two-dimensional modelling of the ICC pacemaker activity according to a phase model of weakly coupled oscillators showed that network properties (coupling strength between oscillators, frequency gradient and frequency noise) strongly influence pacemaker network activity and subsequent motor patterns. The model explains motor patterns observed in physiological conditions and provides predictions and testable hypotheses for effects of ICC loss and frequency modulation on the motor patterns. Interstitial cells of Cajal (ICC) are the pacemaker cells of gut motility and are associated with motility disorders. Interstitial cells of Cajal form a network, but the contributions of its network properties to gut physiology and dysfunction are poorly understood. We modelled an ICC network as a two-dimensional network of weakly coupled oscillators with a frequency gradient and showed changes over time in video and graphical formats. Model parameters were obtained from slow-wave-driven contraction patterns in the mouse intestine and pacemaker slow-wave activities from the cat intestine. Marked changes in propagating oscillation patterns (including changes from propagation to non-propagating) were observed by changing network parameters (coupling strength between oscillators, the frequency gradient and frequency noise), which affected synchronization, propagation velocity and occurrence of dislocations (termination of an oscillation). Complete uncoupling of a circumferential ring of oscillators caused the proximal and distal section to desynchronize, but complete synchronization was maintained with only a single oscillator connecting the sections with high enough coupling. The network of oscillators could withstand loss; even with 40% of oscillators lost randomly within the network, significant synchronization and anterograde propagation remained. A local increase in pacemaker frequency diminished anterograde propagation; the effects were strongly dependent on location, frequency gradient and coupling strength. In summary, the model puts forth the hypothesis that fundamental changes in oscillation patterns (ICC slow-wave activity or circular muscle contractions) can occur through physiological modulation of network properties. Strong evidence is provided to accept the ICC network as a system of coupled oscillators. © 2016 The Authors. Experimental Physiology © 2016 The Physiological Society.

  4. UWB multi-burst transmit driver for averaging receivers

    DOEpatents

    Dallum, Gregory E

    2012-11-20

    A multi-burst transmitter for ultra-wideband (UWB) communication systems generates a sequence of precisely spaced RF bursts from a single trigger event. There are two oscillators in the transmitter circuit, a gated burst rate oscillator and a gated RF burst or RF power output oscillator. The burst rate oscillator produces a relatively low frequency, i.e., MHz, square wave output for a selected transmit cycle, and drives the RF burst oscillator, which produces RF bursts of much higher frequency, i.e., GHz, during the transmit cycle. The frequency of the burst rate oscillator sets the spacing of the RF burst packets. The first oscillator output passes through a bias driver to the second oscillator. The bias driver conditions, e.g., level shifts, the signal from the first oscillator for input into the second oscillator, and also controls the length of each RF burst. A trigger pulse actuates a timing circuit, formed of a flip-flop and associated reset time delay circuit, that controls the operation of the first oscillator, i.e., how long it oscillates (which defines the transmit cycle).

  5. Ionization oscillations in Hall accelerators

    NASA Astrophysics Data System (ADS)

    Barral, S.; Peradzyński, Z.

    2010-01-01

    The underlying mechanism of low-frequency oscillations in Hall accelerators is investigated theoretically. It is shown that relaxation oscillations arise from a competition between avalanche ionization and the advective transport of the working gas. The model derived recovers the slow progression and fast recession of the ionization front. Analytical approximations of the shape of current pulses and of the oscillation frequency are provided for the case of large amplitude oscillations.

  6. Acupuncture analgesia involves modulation of pain-induced gamma oscillations and cortical network connectivity.

    PubMed

    Hauck, Michael; Schröder, Sven; Meyer-Hamme, Gesa; Lorenz, Jürgen; Friedrichs, Sunja; Nolte, Guido; Gerloff, Christian; Engel, Andreas K

    2017-11-24

    Recent studies support the view that cortical sensory, limbic and executive networks and the autonomic nervous system might interact in distinct manners under the influence of acupuncture to modulate pain. We performed a double-blind crossover design study to investigate subjective ratings, EEG and ECG following experimental laser pain under the influence of sham and verum acupuncture in 26 healthy volunteers. We analyzed neuronal oscillations and inter-regional coherence in the gamma band of 128-channel-EEG recordings as well as heart rate variability (HRV) on two experimental days. Pain ratings and pain-induced gamma oscillations together with vagally-mediated power in the high-frequency bandwidth (vmHF) of HRV decreased significantly stronger during verum than sham acupuncture. Gamma oscillations were localized in the prefrontal cortex (PFC), mid-cingulate cortex (MCC), primary somatosensory cortex and insula. Reductions of pain ratings and vmHF-power were significantly correlated with increase of connectivity between the insula and MCC. In contrast, connectivity between left and right PFC and between PFC and insula correlated positively with vmHF-power without a relationship to acupuncture analgesia. Overall, these findings highlight the influence of the insula in integrating activity in limbic-saliency networks with vagally mediated homeostatic control to mediate antinociception under the influence of acupuncture.

  7. Numerical simulation of the transition to chaos in a dissipative Duffing oscillator with two-frequency excitation

    NASA Astrophysics Data System (ADS)

    Zavrazhina, T. V.

    2007-10-01

    A mathematical modeling technique is proposed for oscillation chaotization in an essentially nonlinear dissipative Duffing oscillator with two-frequency excitation on an invariant torus in ℝ2. The technique is based on the joint application of the parameter continuation method, Floquet stability criteria, bifurcation theory, and the Everhart high-accuracy numerical integration method. This approach is used for the numerical construction of subharmonic solutions in the case when the oscillator passes to chaos through a sequence of period-multiplying bifurcations. The value of a universal constant obtained earlier by the author while investigating oscillation chaotization in dissipative oscillators with single-frequency periodic excitation is confirmed.

  8. Graphene-hexagonal boron nitride resonant tunneling diodes as high-frequency oscillators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gaskell, J.; Fromhold, T. M.; Greenaway, M. T.

    We assess the potential of two-terminal graphene-hexagonal boron nitride-graphene resonant tunneling diodes as high-frequency oscillators, using self-consistent quantum transport and electrostatic simulations to determine the time-dependent response of the diodes in a resonant circuit. We quantify how the frequency and power of the current oscillations depend on the diode and circuit parameters including the doping of the graphene electrodes, device geometry, alignment of the graphene lattices, and the circuit impedances. Our results indicate that current oscillations with frequencies of up to several hundred GHz should be achievable.

  9. Using a laser-Doppler flowmetry to measure pulsatile microcirculation on the kidney in rats

    NASA Astrophysics Data System (ADS)

    Jan, Ming-Yie; Chao, Pin-Tsun; Hsu, Tse-Lin; Wang, Yuh-Yin L.; Wang, Wei-Kung

    2001-10-01

    Although Laser Doppler flowmetery (LDF) been extensively used in measurement of microvascular blood flow of different tissues. However, due to some physiological vibrations, fast oscillations of the renal cortical flux (RCF) are hard to be measured. In the study, a commercial 3mW 780nm Laser Doppler flowmetery, with a single fiber and a de-vibration holder, was used to measure the pulsatile RCF in rats. Considering the fast response due to the heart rate of rats, the time constant (TC) was set to 0.05 second and thus the frequency response is up to 20Hz. Furthermore, a calibration standard and a static blood sample were also measured as the references without the pulsatile driving force. In order not to perturb the RCF with tiny momentum, the applying force that the fiber exerted on the renal surface was controlled below 100 dyne. To enhance the signal to noise ratio (SNR), an averaged periodogram was used to estimate the frequency components of the pulsatile microcirculation. It is found that the dominating fast oscillation of RCF is pulsatile and its harmonic components are directly correlated with those of the heartbeat (correlation coefficient =0.999, P<0.001, n=17). The result shows that, in the kidney, the pulsatile RCF is the dominating component of microcirculation oscillation and driven by the fast propagating blood pressure. This technique could be further utilized to analyze the pharmacological effect and hemodynamic parameters on renal function.

  10. Multichannel brain recordings in behaving Drosophila reveal oscillatory activity and local coherence in response to sensory stimulation and circuit activation

    PubMed Central

    Paulk, Angelique C.; Zhou, Yanqiong; Stratton, Peter; Liu, Li

    2013-01-01

    Neural networks in vertebrates exhibit endogenous oscillations that have been associated with functions ranging from sensory processing to locomotion. It remains unclear whether oscillations may play a similar role in the insect brain. We describe a novel “whole brain” readout for Drosophila melanogaster using a simple multichannel recording preparation to study electrical activity across the brain of flies exposed to different sensory stimuli. We recorded local field potential (LFP) activity from >2,000 registered recording sites across the fly brain in >200 wild-type and transgenic animals to uncover specific LFP frequency bands that correlate with: 1) brain region; 2) sensory modality (olfactory, visual, or mechanosensory); and 3) activity in specific neural circuits. We found endogenous and stimulus-specific oscillations throughout the fly brain. Central (higher-order) brain regions exhibited sensory modality-specific increases in power within narrow frequency bands. Conversely, in sensory brain regions such as the optic or antennal lobes, LFP coherence, rather than power, best defined sensory responses across modalities. By transiently activating specific circuits via expression of TrpA1, we found that several circuits in the fly brain modulate LFP power and coherence across brain regions and frequency domains. However, activation of a neuromodulatory octopaminergic circuit specifically increased neuronal coherence in the optic lobes during visual stimulation while decreasing coherence in central brain regions. Our multichannel recording and brain registration approach provides an effective way to track activity simultaneously across the fly brain in vivo, allowing investigation of functional roles for oscillations in processing sensory stimuli and modulating behavior. PMID:23864378

  11. Laser Raman spectroscopy of the effect of solvent on the low-frequency oscillations of organic molecules

    NASA Astrophysics Data System (ADS)

    Brandt, N. N.; Chikishev, A. Yu.; Dolgovskii, V. I.; Lebedenko, S. I.

    2007-09-01

    The effect of solvent on low-frequency oscillations is studied using an example of the 1,1,2,2-tetrachloroethane (TCE) and 1,1,2,2-tetrabromoethane (TBE) molecules, which exhibit torsional oscillations in the terahertz range. Dimethylsulfoxide (DMSO) and carbon tetrachloride (CTC) are used as solvents. It is demonstrated that a decrease in the concentration of the substance under study in the TBE/CTC, TCE/DMSO, and TCE/CTC mixtures leads to a frequency shift of the low-frequency oscillation. The shift is not observed in the TBE/DMSO mixture but a decrease in the TBE concentration causes significant broadening of the low-frequency line.

  12. A dynamical systems approach for estimating phase interactions between rhythms of different frequencies from experimental data

    PubMed Central

    Goto, Takahiro; Aoyagi, Toshio

    2018-01-01

    Synchronization of neural oscillations as a mechanism of brain function is attracting increasing attention. Neural oscillation is a rhythmic neural activity that can be easily observed by noninvasive electroencephalography (EEG). Neural oscillations show the same frequency and cross-frequency synchronization for various cognitive and perceptual functions. However, it is unclear how this neural synchronization is achieved by a dynamical system. If neural oscillations are weakly coupled oscillators, the dynamics of neural synchronization can be described theoretically using a phase oscillator model. We propose an estimation method to identify the phase oscillator model from real data of cross-frequency synchronized activities. The proposed method can estimate the coupling function governing the properties of synchronization. Furthermore, we examine the reliability of the proposed method using time-series data obtained from numerical simulation and an electronic circuit experiment, and show that our method can estimate the coupling function correctly. Finally, we estimate the coupling function between EEG oscillation and the speech sound envelope, and discuss the validity of these results. PMID:29337999

  13. Frequency and function in the basal ganglia: the origins of beta and gamma band activity.

    PubMed

    Blenkinsop, Alexander; Anderson, Sean; Gurney, Kevin

    2017-07-01

    Neuronal oscillations in the basal ganglia have been observed to correlate with behaviours, although the causal mechanisms and functional significance of these oscillations remain unknown. We present a novel computational model of the healthy basal ganglia, constrained by single unit recordings from non-human primates. When the model is run using inputs that might be expected during performance of a motor task, the network shows emergent phenomena: it functions as a selection mechanism and shows spectral properties that match those seen in vivo. Beta frequency oscillations are shown to require pallido-striatal feedback, and occur with behaviourally relevant cortical input. Gamma oscillations arise in the subthalamic-globus pallidus feedback loop, and occur during movement. The model provides a coherent framework for the study of spectral, temporal and functional analyses of the basal ganglia and lays the foundation for an integrated approach to study basal ganglia pathologies such as Parkinson's disease in silico. Neural oscillations in the basal ganglia (BG) are well studied yet remain poorly understood. Behavioural correlates of spectral activity are well described, yet a quantitative hypothesis linking time domain dynamics and spectral properties to BG function has been lacking. We show, for the first time, that a unified description is possible by interpreting previously ignored structure in data describing globus pallidus interna responses to cortical stimulation. These data were used to expose a pair of distinctive neuronal responses to the stimulation. This observation formed the basis for a new mathematical model of the BG, quantitatively fitted to the data, which describes the dynamics in the data, and is validated against other stimulus protocol experiments. A key new result is that when the model is run using inputs hypothesised to occur during the performance of a motor task, beta and gamma frequency oscillations emerge naturally during static-force and movement, respectively, consistent with experimental local field potentials. This new model predicts that the pallido-striatum connection has a key role in the generation of beta band activity, and that the gamma band activity associated with motor task performance has its origins in the pallido-subthalamic feedback loop. The network's functionality as a selection mechanism also occurs as an emergent property, and closer fits to the data gave better selection properties. The model provides a coherent framework for the study of spectral, temporal and functional analyses of the BG and therefore lays the foundation for an integrated approach to study BG pathologies such as Parkinson's disease in silico. © 2017 The Authors. The Journal of Physiology © 2017 The Physiological Society.

  14. Superburst oscillations: ocean and crustal modes excited by carbon-triggered type I X-ray bursts

    NASA Astrophysics Data System (ADS)

    Chambers, F. R. N.; Watts, A. L.; Cavecchi, Y.; Garcia, F.; Keek, L.

    2018-07-01

    Accreting neutron stars (NS) can exhibit high frequency modulations in their light curves during thermonuclear X-ray bursts, known as burst oscillations. The frequencies can be offset from the spin frequency of the NS by several Hz, and can drift by 1-3 Hz. One possible explanation is a mode in the bursting ocean, the frequency of which would decrease (in the rotating frame) as the burst cools, hence explaining the drifts. Most burst oscillations have been observed during the H/He-triggered bursts; however there has been one observation of oscillations during a superburst; hours long Type I X-ray bursts caused by unstable carbon burning deeper in the ocean. This paper calculates the frequency evolution of an oceanic r mode during a superburst. The rotating frame frequency varies during the burst from 4-14 Hz and is sensitive to the background parameters, in particular the temperature of the ocean and ignition depth. This calculation is compared to the superburst oscillations observed on 4U-1636-536. The predicted mode frequencies (˜10 Hz) would require a spin frequency of ˜592 Hz to match observations; 6 Hz higher than the spin inferred from an oceanic r-mode model for the H/He-triggered burst oscillations. This model also overpredicts the frequency drift during the superburst by 90 per cent.

  15. Superburst oscillations: ocean and crustal modes excited by Carbon-triggered Type I X-ray bursts

    NASA Astrophysics Data System (ADS)

    Chambers, F. R. N.; Watts, A. L.; Cavecchi, Y.; Garcia, F.; Keek, L.

    2018-04-01

    Accreting neutron stars (NS) can exhibit high frequency modulations in their lightcurves during thermonuclear X-ray bursts, known as burst oscillations. The frequencies can be offset from the spin frequency of the NS by several Hz, and can drift by 1-3 Hz. One possible explanation is a mode in the bursting ocean, the frequency of which would decrease (in the rotating frame) as the burst cools, hence explaining the drifts. Most burst oscillations have been observed during H/He triggered bursts, however there has been one observation of oscillations during a superburst; hours' long Type I X-ray bursts caused by unstable carbon burning deeper in the ocean. This paper calculates the frequency evolution of an oceanic r-mode during a superburst. The rotating frame frequency varies during the burst from 4 - 14 Hz, and is sensitive to the background parameters, in particular the temperature of the ocean and ignition depth. This calculation is compared to the superburst oscillations observed on 4U-1636-536. The predicted mode frequencies (˜10 Hz) would require a spin frequency of ˜592 Hz to match observations; 6 Hz higher than the spin inferred from an oceanic r-mode model for the H/He triggered burst oscillations. This model also over-predicts the frequency drift during the superburst by 90%.

  16. High spectral purity Kerr frequency comb radio frequency photonic oscillator

    PubMed Central

    Liang, W.; Eliyahu, D.; Ilchenko, V. S.; Savchenkov, A. A.; Matsko, A. B.; Seidel, D.; Maleki, L.

    2015-01-01

    Femtosecond laser-based generation of radio frequency signals has produced astonishing improvements in achievable spectral purity, one of the basic features characterizing the performance of an radio frequency oscillator. Kerr frequency combs hold promise for transforming these lab-scale oscillators to chip-scale level. In this work we demonstrate a miniature 10 GHz radio frequency photonic oscillator characterized with phase noise better than −60 dBc Hz−1 at 10 Hz, −90 dBc Hz−1 at 100 Hz and −170 dBc Hz−1 at 10 MHz. The frequency stability of this device, as represented by Allan deviation measurements, is at the level of 10−10 at 1–100 s integration time—orders of magnitude better than existing radio frequency photonic devices of similar size, weight and power consumption. PMID:26260955

  17. Subthalamic nucleus long-range synchronization—an independent hallmark of human Parkinson's disease

    PubMed Central

    Moshel, Shay; Shamir, Reuben R.; Raz, Aeyal; de Noriega, Fernando R.; Eitan, Renana; Bergman, Hagai; Israel, Zvi

    2013-01-01

    Beta-band synchronous oscillations in the dorsolateral region of the subthalamic nucleus (STN) of human patients with Parkinson's disease (PD) have been frequently reported. However, the correlation between STN oscillations and synchronization has not been thoroughly explored. The simultaneous recordings of 2390 multi-unit pairs recorded by two parallel microelectrodes (separated by fixed distance of 2 mm, n = 72 trajectories with two electrode tracks >4 mm STN span) in 57 PD patients undergoing STN deep brain stimulation surgery were analyzed. Automatic procedures were utilized to divide the STN into dorsolateral oscillatory and ventromedial non-oscillatory regions, and to quantify the intensity of STN oscillations and synchronicity. Finally, the synchronicity of simultaneously vs. non-simultaneously recorded pairs were compared using a shuffling procedure. Synchronization was observed predominately in the beta range and only between multi-unit pairs in the dorsolateral oscillatory region (n = 615). In paired recordings between sites in the dorsolateral and ventromedial (n = 548) and ventromedial-ventromedial region pairs (n = 1227), no synchronization was observed. Oscillation and synchronicity intensity decline along the STN dorsolateral-ventromedial axis suggesting a fuzzy border between the STN regions. Synchronization strength was significantly correlated to the oscillation power, but synchronization was no longer observed following shuffling. We conclude that STN long-range beta oscillatory synchronization is due to increased neuronal coupling in the Parkinsonian brain and does not merely reflect the outcome of oscillations at similar frequency. The neural synchronization in the dorsolateral (probably the motor domain) STN probably augments the pathological changes in firing rate and patterns of subthalamic neurons in PD patients. PMID:24312018

  18. Beta Oscillatory Dynamics in the Prefrontal and Superior Temporal Cortices Predict Spatial Working Memory Performance.

    PubMed

    Proskovec, Amy L; Wiesman, Alex I; Heinrichs-Graham, Elizabeth; Wilson, Tony W

    2018-05-31

    The oscillatory dynamics serving spatial working memory (SWM), and how such dynamics relate to performance, are poorly understood. To address these topics, the present study recruited 22 healthy adults to perform a SWM task during magnetoencephalography (MEG). The resulting MEG data were transformed into the time-frequency domain, and significant oscillatory responses were imaged using a beamformer. Voxel time series data were extracted from the cluster peaks to quantify the dynamics, while whole-brain partial correlation maps were computed to identify regions where oscillatory strength varied with accuracy on the SWM task. The results indicated transient theta oscillations in spatially distinct subregions of the prefrontal cortices at the onset of encoding and maintenance, which may underlie selection of goal-relevant information. Additionally, strong and persistent decreases in alpha and beta oscillations were observed throughout encoding and maintenance in parietal, temporal, and occipital regions, which could serve sustained attention and maintenance processes during SWM performance. The neuro-behavioral correlations revealed that beta activity within left dorsolateral prefrontal control regions and bilateral superior temporal integration regions was negatively correlated with SWM accuracy. Notably, this is the first study to employ a whole-brain approach to significantly link neural oscillations to behavioral performance in the context of SWM.

  19. Human EEG gamma oscillations in neuropsychiatric disorders.

    PubMed

    Herrmann, C S; Demiralp, T

    2005-12-01

    Due to their small amplitude, the importance of high-frequency EEG oscillations with respect to cognitive functions and disorders is often underestimated as compared to slower oscillations. This article reviews the literature on the alterations of gamma oscillations (about 30-80 Hz) during the course of neuropsychiatric disorders and relates them to a model for the functional role of these oscillations for memory matching. The synchronous firing of neurons in the gamma-band has been proposed to bind multiple features of an object, which are coded in a distributed manner in the brain, and is modulated by cognitive processes such as attention and memory. In certain neuropsychiatric disorders the gamma activity shows significant changes. In schizophrenic patients, negative symptoms correlate with a decrease of gamma responses, whereas a significant increase in gamma amplitudes is observed during positive symptoms such as hallucinations. A reduction is also observed in Alzheimer's Disease (AD), whereas an increase is found in epileptic patients, probably reflecting both cortical excitation and perceptual distortions such as déjà vu phenomena frequently observed in epilepsy. ADHD patients also exhibit increased gamma amplitudes. A hypothesis of a gamma axis of these disorders mainly based on the significance of gamma oscillations for memory matching is formulated.

  20. Phase measurement by using a forced delay-line oscillator and its application for an acoustic fiber sensor.

    PubMed

    Fleyer, Michael; Horowitz, Moshe

    2018-04-02

    We demonstrate, theoretically and experimentally, a new method to measure small changes in the cavity length of oscillators. The method is based on the high sensitivity of the phase of forced delay-line oscillators to changes in their cavity length. The oscillator phase is directly detected by mixing the oscillator output with the injected signal. We describe a comprehensive theoretical model for studying the signal and the noise at the output of a general forced delay-line oscillator with an instantaneous gain saturation and an amplitude-to-phase conversion. The results indicate that the magnitude and the bandwidth of the oscillator response to a small perturbation can be controlled by adjusting the injection ratio and the injected frequency. For signals with a frequency that is smaller than the device bandwidth, the oscillator noise is dominated by the noise of the injected signal. This noise is highly suppressed by mixing the oscillator output with the injected signal. Hence, the device sensitivity at frequencies below its bandwidth is limited only by the internal noise that is added in a single roundtrip in the oscillator cavity. We demonstrate the use of a forced oscillator as an acoustic fiber sensor in an optoelectronic oscillator. A good agreement is obtained between theory and experiments. The magnitude of the output signal can be controlled by adjusting the injection ratio while the noise power at low frequencies is not enhanced as in sensors that are based on a free-running oscillator.

  1. Tympanal spontaneous oscillations reveal mechanisms for the control of amplified frequency in tree crickets

    NASA Astrophysics Data System (ADS)

    Mhatre, Natasha; Robert, Daniel

    2018-05-01

    Tree cricket hearing shows all the features of an actively amplified auditory system, particularly spontaneous oscillations (SOs) of the tympanal membrane. As expected from an actively amplified auditory system, SO frequency and the peak frequency in evoked responses as observed in sensitivity spectra are correlated. Sensitivity spectra also show compressive non-linearity at this frequency, i.e. a reduction in peak height and sharpness with increasing stimulus amplitude. Both SO and amplified frequency also change with ambient temperature, allowing the auditory system to maintain a filter that is matched to song frequency. In tree crickets, remarkably, song frequency varies with ambient temperature. Interestingly, active amplification has been reported to be switched ON and OFF. The mechanism of this switch is as yet unknown. In order to gain insights into this switch, we recorded and analysed SOs as the auditory system transitioned from the passive (OFF) state to the active (ON) state. We found that while SO amplitude did not follow a fixed pattern, SO frequency changed during the ON-OFF transition. SOs were first detected above noise levels at low frequencies, sometimes well below the known song frequency range (0.5-1 kHz lower). SO frequency was observed to increase over the next ˜30 minutes, in the absence of any ambient temperature change, before settling at a frequency within the range of conspecific song. We examine the frequency shift in SO spectra with temperature and during the ON/OFF transition and discuss the mechanistic implications. To our knowledge, such modulation of active auditory amplification, and its dynamics are unique amongst auditory animals.

  2. Driven damped harmonic oscillator resonance with an Arduino

    NASA Astrophysics Data System (ADS)

    Goncalves, A. M. B.; Cena, C. R.; Bozano, D. F.

    2017-07-01

    In this paper we propose a simple experimental apparatus that can be used to show quantitative and qualitative results of resonance in a driven damped harmonic oscillator. The driven oscillation is made by a servo motor, and the oscillation amplitude is measured by an ultrasonic position sensor. Both are controlled by an Arduino board. The frequency of free oscillation measured was campatible with the resonance frequency that was measured.

  3. Changes in Alpha Frequency and Power of the Electroencephalogram during Volatile-Based General Anesthesia.

    PubMed

    Hight, Darren; Voss, Logan J; Garcia, Paul S; Sleigh, Jamie

    2017-01-01

    Oscillations in the electroencephalogram (EEG) at the alpha frequency (8-12 Hz) are thought to be ubiquitous during surgical anesthesia, but the details of how this oscillation responds to ongoing changes in volatile anesthetic concentration have not been well characterized. It is not known how often alpha oscillations are absent in the clinical context, how sensitively alpha frequency and power respond to changes in anesthetic concentration, and what effect increased age has on alpha frequency. Bipolar EEG was recorded frontally from 305 patients undergoing surgery with sevoflurane or desflurane providing general anesthesia. A new method of detecting the presence of alpha oscillations based on the stability of the rate of change of the peak frequency in the alpha range was developed. Linear concentration-response curves were fitted to assess the sensitivity of alpha power and frequency measures to changing levels of anesthesia. Alpha oscillations were seen to be inexplicably absent in around 4% of patients. Maximal alpha power increased with increasing volatile anesthetic concentrations in half of the patients, and decreased in the remaining patients. Alpha frequency decreased with increasing anesthetic concentrations in near to 90% of patients. Increasing age was associated with decreased sensitivity to volatile anesthesia concentrations, and with decreased alpha frequency, which sometimes transitioned into the theta range (5-7 Hz). While peak alpha frequency shows a consistent slowing to increasing volatile concentrations, the peak power of the oscillation does not, suggesting that frequency might be more informative of depth of anesthesia than traditional power based measures during volatile-based anesthesia. The alpha oscillation becomes slower with increasing age, even when the decreased anesthetic needs of older patients were taken into account.

  4. Improving the frequency precision of oscillators by synchronization.

    PubMed

    Cross, M C

    2012-04-01

    Improving the frequency precision by synchronizing a lattice of N oscillators with disparate frequencies is studied in the phase reduction limit. In the general case where the coupling is not purely dissipative the synchronized state consists of targetlike waves radiating from a local source, which is a region of higher-frequency oscillators. In this state the improvement of the frequency precision is shown to be independent of N for large N, but instead depends on the disorder and reflects the dependence of the frequency of the synchronized state on just those oscillators in the source region of the waves. These results are obtained by a mapping of the nonlinear phase dynamics onto the linear Anderson problem of the quantum mechanics of electrons on a random lattice in the tight-binding approximation.

  5. Observation of beat oscillation generation by coupled waves associated with parametric decay during radio frequency wave heating of a spherical tokamak plasma.

    PubMed

    Nagashima, Yoshihiko; Oosako, Takuya; Takase, Yuichi; Ejiri, Akira; Watanabe, Osamu; Kobayashi, Hiroaki; Adachi, Yuuki; Tojo, Hiroshi; Yamaguchi, Takashi; Kurashina, Hiroki; Yamada, Kotaro; An, Byung Il; Kasahara, Hiroshi; Shimpo, Fujio; Kumazawa, Ryuhei; Hayashi, Hiroyuki; Matsuzawa, Haduki; Hiratsuka, Junichi; Hanashima, Kentaro; Kakuda, Hidetoshi; Sakamoto, Takuya; Wakatsuki, Takuma

    2010-06-18

    We present an observation of beat oscillation generation by coupled modes associated with parametric decay instability (PDI) during radio frequency (rf) wave heating experiments on the Tokyo Spherical Tokamak-2. Nearly identical PDI spectra, which are characterized by the coexistence of the rf pump wave, the lower-sideband wave, and the low-frequency oscillation in the ion-cyclotron range of frequency, are observed at various locations in the edge plasma. A bispectral power analysis was used to experimentally discriminate beat oscillation from the resonant mode for the first time. The pump and lower-sideband waves have resonant mode components, while the low-frequency oscillation is exclusively excited by nonlinear coupling of the pump and lower-sideband waves. Newly discovered nonlocal transport channels in spectral space and in real space via PDI are described.

  6. Common medial frontal mechanisms of adaptive control in humans and rodents

    PubMed Central

    Frank, Michael J.; Laubach, Mark

    2013-01-01

    In this report, we describe how common brain networks within the medial frontal cortex facilitate adaptive behavioral control in rodents and humans. We demonstrate that low frequency oscillations below 12 Hz are dramatically modulated after errors in humans over mid-frontal cortex and in rats within prelimbic and anterior cingulate regions of medial frontal cortex. These oscillations were phase-locked between medial frontal cortex and motor areas in both rats and humans. In rats, single neurons that encoded prior behavioral outcomes were phase-coherent with low-frequency field oscillations particularly after errors. Inactivating medial frontal regions in rats led to impaired behavioral adjustments after errors, eliminated the differential expression of low frequency oscillations after errors, and increased low-frequency spike-field coupling within motor cortex. Our results describe a novel mechanism for behavioral adaptation via low-frequency oscillations and elucidate how medial frontal networks synchronize brain activity to guide performance. PMID:24141310

  7. Fishbone Oscillations in the Experimental Advanced Superconductivity Tokamak

    NASA Astrophysics Data System (ADS)

    Xu, Li-Qing; Hu, Li-Qun; Yuan, Yi; Li, Ying-Ying; Zhong, Guo-Qiang; Liu, Hai-Qing; Chen, Kai-Yun; Shi, Tong-Hui; Duan, Yan-Min

    2018-03-01

    A fishbone oscillation was observed in the neutral beam injection plasma at Experimental Advanced Superconductivity Tokamak (EAST). This m = 1/n = 1 ( m, n: poloidal, toroidal mode numbers, respectively) typical internal kink mode travels in the ion-diamagnetism direction in the poloidal section with a rotation speed close to the ion diamagnetic drift frequency. A high thermal plasma beta and high amounts of energetic ions are necessary for the mode to develop. Fishbone oscillations can expel heavy impurities in the core, which favors sustaining a high-performance plasma. The born frequency of the fishbone oscillation is the ion diamagnetic drift frequency and the chirping down of the frequency during the initial growth phase is the result of a drop in iondiamagnetic drift frequency. The excitation energy is thought to be due to the thermal plasma pressure gradient; however, the development of a fishbone oscillation is related to energetic ions.

  8. Active locking and entanglement in type II optical parametric oscillators

    NASA Astrophysics Data System (ADS)

    Ruiz-Rivas, Joaquín; de Valcárcel, Germán J.; Navarrete-Benlloch, Carlos

    2018-02-01

    Type II optical parametric oscillators are amongst the highest-quality sources of quantum-correlated light. In particular, when pumped above threshold, such devices generate a pair of bright orthogonally-polarized beams with strong continuous-variable entanglement. However, these sources are of limited practical use, because the entangled beams emerge with different frequencies and a diffusing phase difference. It has been proven that the use of an internal wave-plate coupling the modes with orthogonal polarization is capable of locking the frequencies of the emerging beams to half the pump frequency, as well as reducing the phase-difference diffusion, at the expense of reducing the entanglement levels. In this work we characterize theoretically an alternative locking mechanism: the injection of a laser at half the pump frequency. Apart from being less invasive, this method should allow for an easier real-time experimental control. We show that such an injection is capable of generating the desired phase locking between the emerging beams, while still allowing for large levels of entanglement. Moreover, we find an additional region of the parameter space (at relatively large injections) where a mode with well defined polarization is in a highly amplitude-squeezed state.

  9. Solid-state lasers for coherent communication and remote sensing

    NASA Technical Reports Server (NTRS)

    Byer, Robert L.

    1992-01-01

    Semiconductor-diode laser-pumped solid-state lasers have properties that are superior to other lasers for the applications of coherent communication and remote sensing. These properties include efficiency, reliability, stability, and capability to be scaled to higher powers. We have demonstrated that an optical phase-locked loop can be used to lock the frequency of two diode-pumped 1.06 micron Nd:YAG lasers to levels required for coherent communication. Monolithic nonplanar ring oscillators constructed from solid pieces of the laser material provide better than 10 kHz frequency stability over 0.1 sec intervals. We have used active feedback stabilization of the cavity length of these lasers to demonstrate 0.3 Hz frequency stabilization relative to a reference cavity. We have performed experiments and analysis to show that optical parametric oscillators (OPO's) reproduce the frequency stability of the pump laser in outputs that can be tuned to arbitrary wavelengths. Another measurement performed in this program has demonstrated the sub-shot-noise character of correlations of the fluctuations in the twin output of OPO's. Measurements of nonlinear optical coefficients by phase-matched second harmonic generation are helping to resolve inconsistency in these important parameters.

  10. Validation of a Manually Oscillating Chair for In-The-Field Assessment of Dynamic Visual Acuity on Crewmembers Within Hours of Returning from Long-Duration Spaceflight

    NASA Technical Reports Server (NTRS)

    Kreutzberg, G. A.; Rosenberg, M. J. F.; Peters, B. T.; Reschke, M. F.

    2017-01-01

    Due to the deconditioned state of crewmembers in the initial hours after landing, it is safer and more practical to perform a vision test while seated in a chair versus walking on a treadmill. The purpose of this study was to validate the ability of a manually operated oscillating chair to produce the oscillatory frequency and displacement equivalent of walking on a treadmill at a 4 mph pace. A fast Fourier transform (FFT)was performed on the vertical trunk acceleration to compare the peak and spread of the distribution of oscillation frequencies for each oscillating condition. Peak oscillation frequencies achieved with the manual chair were lower and more variable than those of treadmill walking and the automatic chair. This can mostly be attributed to operator fatigue. However, DVA scores across conditions were not significantly different, indicating that the manual chair can provide adequate vertical oscillation frequency and displacement with the added advantage of being portable enough for testing outside a laboratory. Furthermore the automatic chair very closely matches the oscillation frequency of treadmill walking, making it an ideal method for testing DVA in a laboratory setting.

  11. Optical Links and RF Distribution for Antenna Arrays

    NASA Technical Reports Server (NTRS)

    Huang, Shouhua; Calhoun, Malcolm; Tjoelker, Robert

    2006-01-01

    An array of three antennas has recently been developed at the NASA Jet Propulsion Laboratory capable of detecting signals at X and Ka band. The array requires a common frequency reference and high precision phase alignment to correlate received signals. Frequency and timing references are presently provided from a remotely located hydrogen maser and clock through a combination of commercially and custom developed optical links. The selected laser, photodetector, and fiber components have been tested under anticipated thermal and simulated antenna rotation conditions. The resulting stability limitations due to thermal perturbations or induced stress on the optical fiber have been characterized. Distribution of the X band local oscillator includes a loop back and precision phase monitor to enable correlation of signals received from each antenna.

  12. Pulsing frequency induced change in optical constants and dispersion energy parameters of WO3 films grown by pulsed direct current magnetron sputtering

    NASA Astrophysics Data System (ADS)

    Punitha, K.; Sivakumar, R.; Sanjeeviraja, C.

    2014-03-01

    In this work, we present the pulsing frequency induced change in the structural, optical, vibrational, and luminescence properties of tungsten oxide (WO3) thin films deposited on microscopic glass and fluorine doped tin oxide (SnO2:F) coated glass substrates by pulsed dc magnetron sputtering technique. The WO3 films deposited on SnO2:F substrate belongs to monoclinic phase. The pulsing frequency has a significant influence on the preferred orientation and crystallinity of WO3 film. The maximum optical transmittance of 85% was observed for the film and the slight shift in transmission threshold towards higher wavelength region with increasing pulsing frequency revealed the systematic reduction in optical energy band gap (3.78 to 3.13 eV) of the films. The refractive index (n) of films are found to decrease (1.832 to 1.333 at 550 nm) with increasing pulsing frequency and the average value of extinction coefficient (k) is in the order of 10-3. It was observed that the dispersion data obeyed the single oscillator of the Wemple-Didomenico model, from which the dispersion energy (Ed) parameters, dielectric constants, plasma frequency, oscillator strength, and oscillator energy (Eo) of WO3 films were calculated and reported for the first time due to variation in pulsing frequency during deposition by pulsed dc magnetron sputtering. The Eo is change between 6.30 and 3.88 eV, while the Ed varies from 25.81 to 7.88 eV, with pulsing frequency. The Raman peak observed at 1095 cm-1 attributes the presence of W-O symmetric stretching vibration. The slight shift in photoluminescence band is attributed to the difference in excitons transition. We have made an attempt to discuss and correlate these results with the light of possible mechanisms underlying the phenomena.

  13. α-Adrenergic effects on low-frequency oscillations in blood pressure and R-R intervals during sympathetic activation.

    PubMed

    Kiviniemi, Antti M; Frances, Maria F; Tiinanen, Suvi; Craen, Rosemary; Rachinsky, Maxim; Petrella, Robert J; Seppänen, Tapio; Huikuri, Heikki V; Tulppo, Mikko P; Shoemaker, J Kevin

    2011-08-01

    The present study was designed to address the contribution of α-adrenergic modulation to the genesis of low-frequency (LF; 0.04-0.15 Hz) oscillations in R-R interval (RRi), blood pressure (BP) and muscle sympathetic nerve activity (MSNA) during different sympathetic stimuli. Blood pressure and RRi were measured continuously in 12 healthy subjects during 5 min periods each of lower body negative pressure (LBNP; -40 mmHg), static handgrip exercise (HG; 20% of maximal force) and postexercise forearm circulatory occlusion (PECO) with and without α-adrenergic blockade by phentolamine. Muscle sympathetic nerve activity was recorded in five subjects during LBNP and in six subjects during HG and PECO. Low-frequency powers and median frequencies of BP, RRi and MSNA were calculated from power spectra. Low-frequency power during LBNP was lower with phentolamine versus without for both BP and RRi oscillations (1.6 ± 0.6 versus 1.2 ± 0.7 ln mmHg(2), P = 0.049; and 6.9 ± 0.8 versus 5.4 ± 0.9 ln ms(2), P = 0.001, respectively). In contrast, the LBNP with phentolamine increased the power of high-frequency oscillations (0.15-0.4 Hz) in BP and MSNA (P < 0.01 for both), which was not observed during saline infusion. Phentolamine also blunted the increases in the LBNP-induced increase in frequency of LF oscillations in BP and RRi. Phentolamine decreased the LF power of RRi during HG (P = 0.015) but induced no other changes in LF powers or frequencies during HG. Phentolamine resulted in decreased frequency of LF oscillations in RRi (P = 0.004) during PECO, and a similar tendency was observed in BP and MSNA. The power of LF oscillation in MSNA did not change during any intervention. We conclude that α-adrenergic modulation contributes to LF oscillations in BP and RRi during baroreceptor unloading (LBNP) but not during static exercise. Also, α-adrenergic modulation partly explains the shift to a higher frequency of LF oscillations during baroreceptor unloading and muscle metaboreflex activation.

  14. A Population of Indirect Pathway Striatal Projection Neurons Is Selectively Entrained to Parkinsonian Beta Oscillations

    PubMed Central

    Vinciati, Federica

    2017-01-01

    Classical schemes of basal ganglia organization posit that parkinsonian movement difficulties presenting after striatal dopamine depletion stem from the disproportionate firing rates of spiny projection neurons (SPNs) therein. There remains, however, a pressing need to elucidate striatal SPN firing in the context of the synchronized network oscillations that are abnormally exaggerated in cortical–basal ganglia circuits in parkinsonism. To address this, we recorded unit activities in the dorsal striatum of dopamine-intact and dopamine-depleted rats during two brain states, respectively defined by cortical slow-wave activity (SWA) and activation. Dopamine depletion escalated striatal net output but had contrasting effects on “direct pathway” SPNs (dSPNs) and “indirect pathway” SPNs (iSPNs); their firing rates became imbalanced, and they disparately engaged in network oscillations. Disturbed striatal activity dynamics relating to the slow (∼1 Hz) oscillations prevalent during SWA partly generalized to the exaggerated beta-frequency (15–30 Hz) oscillations arising during cortical activation. In both cases, SPNs exhibited higher incidences of phase-locked firing to ongoing cortical oscillations, and SPN ensembles showed higher levels of rhythmic correlated firing, after dopamine depletion. Importantly, in dopamine-depleted striatum, a widespread population of iSPNs, which often displayed excessive firing rates and aberrant phase-locked firing to cortical beta oscillations, preferentially and excessively synchronized their firing at beta frequencies. Conversely, dSPNs were neither hyperactive nor synchronized to a large extent during cortical activation. These data collectively demonstrate a cell type-selective entrainment of SPN firing to parkinsonian beta oscillations. We conclude that a population of overactive, excessively synchronized iSPNs could orchestrate these pathological rhythms in basal ganglia circuits. SIGNIFICANCE STATEMENT Chronic depletion of dopamine from the striatum, a part of the basal ganglia, causes some symptoms of Parkinson's disease. Here, we elucidate how dopamine depletion alters striatal neuron firing in vivo, with an emphasis on defining whether and how spiny projection neurons (SPNs) engage in the synchronized beta-frequency (15–30 Hz) oscillations that become pathologically exaggerated throughout basal ganglia circuits in parkinsonism. We discovered that a select population of so-called “indirect pathway” SPNs not only fire at abnormally high rates, but are also particularly prone to being recruited to exaggerated beta oscillations. Our results provide an important link between two complementary theories that explain the presentation of disease symptoms on the basis of changes in firing rate or firing synchronization/rhythmicity. PMID:28847810

  15. Frequency control of a spin-torque oscillator using magnetostrictive anisotropy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Park, Min Gyu Albert; Lee, Seok-Hee, E-mail: bgpark@kaist.ac.kr, E-mail: shlee@kaist.edu; Baek, Seung-heon Chris

    2016-01-11

    We report the working principle of a spin-torque oscillator, of which the frequency is efficiently controlled by manipulating the magnetostrictive anisotropy. To justify the scheme, we simulate a conventional magnetic-tunnel junction-based oscillator which is fabricated on a piezoelectric material. By applying mechanical stress to a free layer using a piezoelectric material, the oscillation frequency can be controlled to ensure a broad tuning range without a significant reduction of the dynamic resistance variation. Such controllability, which appears in the absence of an external magnetic field, will not only enable the integration of spin-torque oscillators and conventional complimentary metal-oxide semiconductor technology butmore » will also broaden the applicability of spin-torque oscillators.« less

  16. Network Oscillations Drive Correlated Spiking of ON and OFF Ganglion Cells in the rd1 Mouse Model of Retinal Degeneration

    PubMed Central

    Margolis, David J.; Gartland, Andrew J.; Singer, Joshua H.; Detwiler, Peter B.

    2014-01-01

    Following photoreceptor degeneration, ON and OFF retinal ganglion cells (RGCs) in the rd-1/rd-1 mouse receive rhythmic synaptic input that elicits bursts of action potentials at ∼10 Hz. To characterize the properties of this activity, RGCs were targeted for paired recording and morphological classification as either ON alpha, OFF alpha or non-alpha RGCs using two-photon imaging. Identified cell types exhibited rhythmic spike activity. Cross-correlation of spike trains recorded simultaneously from pairs of RGCs revealed that activity was correlated more strongly between alpha RGCs than between alpha and non-alpha cell pairs. Bursts of action potentials in alpha RGC pairs of the same type, i.e. two ON or two OFF cells, were in phase, while bursts in dissimilar alpha cell types, i.e. an ON and an OFF RGC, were 180 degrees out of phase. This result is consistent with RGC activity being driven by an input that provides correlated excitation to ON cells and inhibition to OFF cells. A2 amacrine cells were investigated as a candidate cellular mechanism and found to display 10 Hz oscillations in membrane voltage and current that persisted in the presence of antagonists of fast synaptic transmission and were eliminated by tetrodotoxin. Results support the conclusion that the rhythmic RGC activity originates in a presynaptic network of electrically coupled cells including A2s via a Na+-channel dependent mechanism. Network activity drives out of phase oscillations in ON and OFF cone bipolar cells, entraining similar frequency fluctuations in RGC spike activity over an area of retina that migrates with changes in the spatial locus of the cellular oscillator. PMID:24489706

  17. The direct relationship between inhibitory currents and local field potentials.

    PubMed

    Trevelyan, Andrew J

    2009-12-02

    The frequency profiles of various extracellular field oscillations are known to reflect functional brain states, yet we lack detailed explanations of how these brain oscillations arise. Of particular clinical relevance are the high-frequency oscillations (HFOs) associated with interictal events and the onset of seizures. These time periods are also when pyramidal firing appears to be vetoed by high-frequency volleys of inhibitory synaptic currents, thereby providing an inhibitory restraint that opposes epileptiform spread (Trevelyan et al., 2006, 2007). The pattern and timing of this inhibitory volley is suggestive of a causal relationship between the restraint and HFOs. I show that at these times, isolated inhibitory currents from single pyramidal cells have a similarity to the extracellular signal that significantly exceeds chance. The ability to extrapolate from discrete currents in single cells to the extracellular signal arises because these inhibitory currents are synchronized in local populations of pyramidal cells. The visibility of these inhibitory currents in the field recordings is greatest when local pyramidal activity is suppressed: the correlation between the inhibitory currents and the field signal becomes worse when local activity increases, suggestive of a switch from one source of HFO to another as the restraint starts to fail. This association suggests that a significant component of HFOs reflects the last act of defiance in the face of an advancing ictal event.

  18. Phase and frequency structure of superradiance pulses generated by relativistic Ka-band backward-wave oscillator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rostov, V. V.; Romanchenko, I. V.; Elchaninov, A. A.

    2016-08-15

    Phase and frequency stability of electromagnetic oscillations in sub-gigawatt superradiance (SR) pulses generated by an extensive slow-wave structure of a relativistic Ka-band backward-wave oscillator were experimentally investigated. Data on the frequency tuning and radiation phase stability of SR pulses with a variation of the energy and current of electron beam were obtained.

  19. Chimera Type Behavior in Nonlocal Coupling System with Two Different Inherent Frequencies

    NASA Astrophysics Data System (ADS)

    Lin, Larry; Li, Ping-Cheng; Tseng, Hseng-Che

    2014-03-01

    From the research of Kuramoto and Strogatz, arrays of identical oscillators can display a remarkable pattern, named chimera state, in which phase-locked oscillators coexist with drifting ones in nonlocal coupling oscillator system. We consider further in this study, two groups of oscillators with different inherent frequencies and arrange them in a ring. When the difference of the inherent frequencies is within some specific parameter range, oscillators of nonlocal coupling system show two distinct chimera states. When the parameter value exceeds some threshold value, two chimera states disappear. They show different features. The statistical dynamic behavior of the system can be described by Kuramoto theory.

  20. A report on the gravitational redshift test for non-metric theories of gravitation

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The frequencies of two atomic hydrogen masers and of three superconducting cavity stabilized oscillators were compared as the ensemble of oscillators was moved in the Sun's gravitational field by the rotation and orbital motion of the Earth. Metric gravitation theories predict that the gravitational redshifts of the two types of oscillators are identical, and that there should be no relative frequency shift between the oscillators; nonmetric theories, in contrast, predict a frequency shift between masers and SCSOs that is proportional to the change in solar gravitational potential experienced by the oscillators. The results are consistent with metric theories of gravitation at a level of 2%.

  1. CAVITY EXCITATION CIRCUIT

    DOEpatents

    Franck, J.V.

    1959-10-20

    An electronic oscillator is described for energizing a resonant cavity and to a system for stabilizing the operatin g frequency of the oscillator at the particular frequency necessary to establish a particular preferred field configuration or mode in the cavity, in this instance a linear accelerator. A freely rnnning oscillator has an output coupled to a resonant cavity wherein a field may be built up at any one of several adjacent frequencies. A pickup loop in the cavity is suitably shielded and positioned in the cavity so that only energy at the panticular desired frequency is fed back to stabilize the oscillator. A phase and gain control is in cluded in the feedback line.

  2. Concentration Measurements in Self-Excited, Momentum-Dominated Helium Jets

    NASA Technical Reports Server (NTRS)

    Yildirim, Bekir Sedat

    2004-01-01

    Flow structure of momentum-dominated pure helium jets discharged vertically into ambient air was investigated using high-speed rainbow schlieren deflectometry (RSD) technique. Effects of the operating parameters, i.e., Reynolds number (Re) and Richardson number (Ri), on the oscillatory behavior of the flow were examined over a range of experimental conditions. To seek the individual effect of these parameters, one of them was fixed and the other was varied with certain constraints. Measurements revealed highly periodic oscillations in the laminar region as well as high regularity in transition and turbulent regions. Maximum spectral power profiles at different axial locations indicated the oscillation amplitude increasing until the breakdown of the jet in the turbulent regime. The transition from the laminar to turbulent flow was also investigated. Fast Fourier transform analysis performed in the transition regime showed that the flow oscillates at a unique frequency, which was the same in the upstream laminar flow region. Measured deflection angle data were used in Abel inversion algorithm to construct the helium concentration fields. Instantaneous helium concentration contours revealed changes in the flow structure and evolution of vortical structures during an oscillation cycle. Temporal evolution plots of helium concentration at different axial location showed repeatable oscillations at all axial and radial locations up to the turbulent regime. A cross-correlation technique, applied to find the spatial displacements of the vortical structures, provided correlation coefficient peaks between consecutive schlieren images. Results show that the vortical structure convected and accelerated only in the axial direction.

  3. The effect of low-frequency oscillations on cardio-respiratory synchronization. Observations during rest and exercise

    NASA Astrophysics Data System (ADS)

    Kenwright, D. A.; Bahraminasab, A.; Stefanovska, A.; McClintock, P. V. E.

    2008-10-01

    We show that the transitions which occur between close orders of synchronization in the cardiorespiratory system are mainly due to modulation of the cardiac and respiratory processes by low-frequency components. The experimental evidence is derived from recordings on healthy subjects at rest and during exercise. Exercise acts as a perturbation of the system that alters the mean cardiac and respiratory frequencies and changes the amount of their modulation by low-frequency oscillations. The conclusion is supported by numerical evidence based on a model of phase-coupled oscillators, with white noise and lowfrequency noise. Both the experimental and numerical approaches confirm that low-frequency oscillations play a significant role in the transitional behavior between close orders of synchronization.

  4. Quantum Correlations of Light from a Room-Temperature Mechanical Oscillator

    NASA Astrophysics Data System (ADS)

    Sudhir, V.; Schilling, R.; Fedorov, S. A.; Schütz, H.; Wilson, D. J.; Kippenberg, T. J.

    2017-07-01

    When an optical field is reflected from a compliant mirror, its intensity and phase become quantum-correlated due to radiation pressure. These correlations form a valuable resource: the mirror may be viewed as an effective Kerr medium generating squeezed states of light, or the correlations may be used to erase backaction from an interferometric measurement of the mirror's position. To date, optomechanical quantum correlations have been observed in only a handful of cryogenic experiments, owing to the challenge of distilling them from thermomechanical noise. Accessing them at room temperature, however, would significantly extend their practical impact, with applications ranging from gravitational wave detection to chip-scale accelerometry. Here, we observe broadband quantum correlations developed in an optical field due to its interaction with a room-temperature nanomechanical oscillator, taking advantage of its high-cooperativity near-field coupling to an optical microcavity. The correlations manifest as a reduction in the fluctuations of a rotated quadrature of the field, in a frequency window spanning more than an octave below mechanical resonance. This is due to coherent cancellation of the two sources of quantum noise contaminating the measured quadrature—backaction and imprecision. Supplanting the backaction force with an off-resonant test force, we demonstrate the working principle behind a quantum-enhanced "variational" force measurement.

  5. Optical Stabilization of a Microwave Oscillator for Fountain Clock Interrogation.

    PubMed

    Lipphardt, Burghard; Gerginov, Vladislav; Weyers, Stefan

    2017-04-01

    We describe an optical frequency stabilization scheme of a microwave oscillator that is used for the interrogation of primary cesium fountain clocks. Because of its superior phase noise properties, this scheme, which is based on an ultrastable laser and a femtosecond laser frequency comb, overcomes the frequency instability limitations of fountain clocks given by the previously utilized quartz-oscillator-based frequency synthesis. The presented scheme combines the transfer of the short-term frequency instability of an optical cavity and the long-term frequency instability of a hydrogen maser to the microwave oscillator and is designed to provide continuous long-term operation for extended measurement periods of several weeks. The utilization of the twofold stabilization scheme on the one hand ensures the referencing of the fountain frequency to the hydrogen maser frequency and on the other hand results in a phase noise level of the fountain interrogation signal, which enables fountain frequency instabilities at the 2.5 ×10 -14 (τ/s) -1/2 level that are quantum projection noise limited.

  6. The effect of a hot, spherical scattering cloud on quasi-periodic oscillation behavior

    NASA Astrophysics Data System (ADS)

    Bussard, R. W.; Weisskopf, M. C.; Elsner, R. F.; Shibazaki, N.

    1988-04-01

    A Monte Carlo technique is used to investigate the effects of a hot electron scattering cloud surrounding a time-dependent X-ray source. Results are presented for the time-averaged emergent energy spectra and the mean residence time in the cloud as a function of energy. Moreover, after Fourier transforming the scattering Green's function, it is shown how the cloud affects both the observed power spectrum of a time-dependent source and the cross spectrum (Fourier transform of a cross correlation between energy bands). It is found that the power spectra intrinsic to the source are related to those observed by a relatively simple frequency-dependent multiplicative factor (a transmission function). The cloud can severely attenuate high frequencies in the power spectra, depending on optical depth, and, at lower frequencies, the transmission function has roughly a Lorentzian shape. It is also found that if the intrinsic energy spectrum is constant in time, the phase of the cross spectrum is determined entirely by scattering. Finally, the implications of the results for studies of the X-ray quasi-periodic oscillators are discussed.

  7. Slowing of the hippocampal θ-rhythm correlates with anesthetic-induced amnesia

    PubMed Central

    Perouansky, Misha; Rau, Vinuta; Ford, Tim; Oh, S. Irene; Perkins, Mark; Eger, Edmond I.; Pearce, Robert A.

    2010-01-01

    Background Temporary, antegrade amnesia is one of the core desirable endpoints of general anesthesia. Multiple lines of evidence support a role for the hippocampal θ-rhythm, a synchronized rhythmic oscillation of field potentials at 4–12 Hz, in memory formation. Previous studies have revealed a disruption of the θ-rhythm at surgical levels of anesthesia. We hypothesized that modulation of θ-rhythm would also occur at subhypnotic but amnestic concentrations. Therefore we examined the effect of three inhaled agents on properties of the θ-rhythm that are considered to be critical for the formation of hippocampus-dependent memories. Methods We studied the effects of halothane and nitrous oxide, two agents known to modulate different molecular targets (GABAergic vs. non-GABAergic, respectively), and isoflurane (both GABAergic and non-GABAergic targets), on fear-conditioned learning and θ-oscillations in freely behaving rats. Results All three anesthetics slowed θ-peak frequency in proportion to their inhibition of fear conditioning (by 1 Hz, 0.7 Hz and 0.5 Hz for 0.32% isoflurane, 60% N2O and 0.24% halothane). The anesthetics inconsistently affected other characteristics of θ-oscillations. Conclusions At sub-hypnotic amnestic concentrations, θ-oscillation frequency was the parameter most consistently affected by these three anesthetics. These results are consistent with the hypothesis that modulation of the θ-rhythm contributes to anesthetic-induced amnesia. PMID:21042201

  8. Interaction of oscillations, and their suppression via deep brain stimulation, in a model of the cortico-basal ganglia network.

    PubMed

    Kang, Guiyeom; Lowery, Madeleine M

    2013-03-01

    Growing evidence suggests that synchronized neural oscillations in the cortico-basal ganglia network may play a critical role in the pathophysiology of Parkinson's disease. In this study, a new model of the closed loop network is used to explore the generation and interaction of network oscillations and their suppression through deep brain stimulation (DBS). Under simulated dopamine depletion conditions, increased gain through the hyperdirect pathway resulted in the interaction of neural oscillations at different frequencies in the cortex and subthalamic nucleus (STN), leading to the emergence of synchronized oscillations at a new intermediate frequency. Further increases in synaptic gain resulted in the cortex driving synchronous oscillatory activity throughout the network. When DBS was added to the model a progressive reduction in STN power at the tremor and beta frequencies was observed as the frequency of stimulation was increased, with resonance effects occurring for low frequency DBS (40 Hz) in agreement with experimental observations. The results provide new insights into the mechanisms by which synchronous oscillations can arise within the network and how DBS may suppress unwanted oscillatory activity.

  9. Frequency stabilization in nonlinear MEMS and NEMS oscillators

    DOEpatents

    Lopez, Omar Daniel; Antonio, Dario

    2014-09-16

    An illustrative system includes an amplifier operably connected to a phase shifter. The amplifier is configured to amplify a voltage from an oscillator. The phase shifter is operably connected to a driving amplitude control, wherein the phase shifter is configured to phase shift the amplified voltage and is configured to set an amplitude of the phase shifted voltage. The oscillator is operably connected to the driving amplitude control. The phase shifted voltage drives the oscillator. The oscillator is at an internal resonance condition, based at least on the amplitude of the phase shifted voltage, that stabilizes frequency oscillations in the oscillator.

  10. Numerical study on the instabilities in H2-air rotating detonation engines

    NASA Astrophysics Data System (ADS)

    Liu, Yan; Zhou, Weijiang; Yang, Yunjun; Liu, Zhou; Wang, Jianping

    2018-04-01

    Numerical simulations of rotating detonation engines (RDEs) are performed using two-dimensional Euler equations and a detailed chemistry model of H2-air. Two propagation modes, the one-wave mode and the two-wave mode, are observed in the RDEs. The instabilities of the RDEs are studied and analyzed specifically. A low frequency instability and a high frequency instability are found from the pressure-time trace measured at a fixed location and the average density-time trace of the RDEs. For the low frequency instability, the pressure peak of the pressure-time trace oscillates with a low frequency while the average density is stable. The deviation between the measurement location and the location of the detonation wave results in the low frequency instability. For the high frequency instability, the average density of the RDEs oscillates regularly with a single frequency while the pressure oscillates irregularly with several frequencies. The oscillation of the detonation wave height results in the high frequency instability. Furthermore, the low frequency instability and the high frequency instability both occur in the one-wave and two-wave mode RDEs.

  11. Interannual-to-multidecadal hydroclimate variability and its sectoral impacts in northeastern Argentina

    NASA Astrophysics Data System (ADS)

    Lovino, Miguel A.; Müller, Omar V.; Müller, Gabriela V.; Sgroi, Leandro C.; Baethgen, Walter E.

    2018-06-01

    This study examines the joint variability of precipitation, river streamflow and temperature over northeastern Argentina; advances the understanding of their links with global SST forcing; and discusses their impacts on water resources, agriculture and human settlements. The leading patterns of variability, and their nonlinear trends and cycles are identified by means of a principal component analysis (PCA) complemented with a singular spectrum analysis (SSA). Interannual hydroclimatic variability centers on two broad frequency bands: one of 2.5-6.5 years corresponding to El Niño Southern Oscillation (ENSO) periodicities and the second of about 9 years. The higher frequencies of the precipitation variability (2.5-4 years) favored extreme events after 2000, even during moderate extreme phases of the ENSO. Minimum temperature is correlated with ENSO with a main frequency close to 3 years. Maximum temperature time series correlate well with SST variability over the South Atlantic, Indian and Pacific oceans with a 9-year frequency. Interdecadal variability is characterized by low-frequency trends and multidecadal oscillations that have induced a transition from dryer and cooler climate to wetter and warmer decades starting in the mid-twentieth century. The Paraná River streamflow is influenced by North and South Atlantic SSTs with bidecadal periodicities. The hydroclimate variability at all timescales had significant sectoral impacts. Frequent wet events between 1970 and 2005 favored floods that affected agricultural and livestock productivity and forced population displacements. On the other hand, agricultural droughts resulted in soil moisture deficits that affected crops at critical growth stages. Hydrological droughts affected surface water resources, causing water and food scarcity and stressing the capacity for hydropower generation. Lastly, increases in minimum temperature reduced wheat and barley yields.

  12. Active shunt capacitance cancelling oscillator circuit

    DOEpatents

    Wessendorf, Kurt O.

    2003-09-23

    An oscillator circuit is disclosed which can be used to produce oscillation using a piezoelectric crystal, with a frequency of oscillation being largely independent of any shunt capacitance associated with the crystal (i.e. due to electrodes on the surfaces of the crystal and due to packaging and wiring for the crystal). The oscillator circuit is based on a tuned gain stage which operates the crystal at a frequency, f, near a series resonance frequency, f.sub.S. The oscillator circuit further includes a compensation circuit that supplies all the ac current flow through the shunt resistance associated with the crystal so that this ac current need not be supplied by the tuned gain stage. The compensation circuit uses a current mirror to provide the ac current flow based on the current flow through a reference capacitor that is equivalent to the shunt capacitance associated with the crystal. The oscillator circuit has applications for driving piezoelectric crystals for sensing of viscous, fluid or solid media by detecting a change in the frequency of oscillation of the crystal and a resonator loss which occur from contact of an exposed surface of the crystal by the viscous, fluid or solid media.

  13. Low-Frequency Oscillations and Transport Processes Induced by Multiscale Transverse Structures in the Polar Wind Outflow: A Three-Dimensional Simulation

    NASA Technical Reports Server (NTRS)

    Ganguli, Supriya B.; Gavrishchaka, Valeriy V.

    1999-01-01

    Multiscale transverse structures in the magnetic-field-aligned flows have been frequently observed in the auroral region by FAST and Freja satellites. A number of multiscale processes, such as broadband low-frequency oscillations and various cross-field transport effects are well correlated with these structures. To study these effects, we have used our three-dimensional multifluid model with multiscale transverse inhomogeneities in the initial velocity profile. Self-consistent-frequency mode driven by local transverse gradients in the generation of the low field-aligned ion flow and associated transport processes were simulated. Effects of particle interaction with the self-consistent time-dependent three-dimensional wave potential have been modeled using a distribution of test particles. For typical polar wind conditions it has been found that even large-scale (approximately 50 - 100 km) transverse inhomogeneities in the flow can generate low-frequency oscillations that lead to significant flow modifications, cross-field particle diffusion, and other transport effects. It has also been shown that even small-amplitude (approximately 10 - 20%) short-scale (approximately 10 km) modulations of the original large-scale flow profile significantly increases low-frequency mode generation and associated cross-field transport, not only at the local spatial scales imposed by the modulations but also on global scales. Note that this wave-induced cross-field transport is not included in any of the global numerical models of the ionosphere, ionosphere-thermosphere, or ionosphere-polar wind. The simulation results indicate that the wave-induced cross-field transport not only affects the ion outflow rates but also leads to a significant broadening of particle phase-space distribution and transverse particle diffusion.

  14. Characterization of Tissue Structure at Varying Length Scales Using Temporal Diffusion Spectroscopy

    PubMed Central

    Gore, John C.; Xu, Junzhong; Colvin, Daniel C.; Yankeelov, Thomas E.; Parsons, Edward C.; Does, Mark D.

    2011-01-01

    The concepts, theoretical behavior and experimental applications of temporal diffusion spectroscopy are reviewed and illustrated. Temporal diffusion spectra are obtained by using oscillating gradient waveforms in diffusion-weighted measurements, and represent the manner in which various spectral components of molecular velocity correlations vary in different geometrical structures that restrict or hinder free movements. Measurements made at different gradient frequencies reveal information on the scale of restrictions or hindrances to free diffusion, and the shape of a spectrum reveals the relative contributions of spatial restrictions at different distance scales. Such spectra differ from other so-called diffusion spectra which depict spatial frequencies and are defined at a fixed diffusion time. Experimentally, oscillating gradients at moderate frequency are more feasible for exploring restrictions at very short distances, which in tissues correspond to structures smaller than cells. We describe the underlying concepts of temporal diffusion spectra and provide analytical expressions for the behavior of the diffusion coefficient as a function of gradient frequency in simple geometries with different dimensions. Diffusion in more complex model media that mimic tissues has been simulated using numerical methods. Experimental measurements of diffusion spectra have been obtained in suspensions of particles and cells, as well as in vivo in intact animals. An observation of particular interest is the increased contrast and heterogeneity observed in tumors using oscillating gradients at moderate frequency compared to conventional pulse gradient methods, and the potential for detecting changes in tumors early in their response to treatment. Computer simulations suggest that diffusion spectral measurements may be sensitive to intracellular structures such as nuclear size, and that changes in tissue diffusion properties may be measured before there are changes in cell density. PMID:20677208

  15. Premonitory slip and tidal triggering of earthquakes

    USGS Publications Warehouse

    Lockner, D.A.; Beeler, N.M.

    1999-01-01

    We have conducted a series of laboratory simulations of earthquakes using granite cylinders containing precut bare fault surfaces at 50 MPa confining pressure. Axial shortening rates between 10-4 and 10-6 mm/s were imposed to simulate tectonic loading. Average loading rate was then modulated by the addition of a small-amplitude sine wave to simulate periodic loading due to Earth tides or other sources. The period of the modulating signal ranged from 10 to 10,000 s. For each combination of amplitude and period of the modulating signal, multiple stick-slip events were recorded to determine the degree of correlation between the timing of simulated earthquakes and the imposed periodic loading function. Over the range of parameters studied, the degree of correlation of earthquakes was most sensitive to the amplitude of the periodic loading, with weaker dependence on the period of oscillations and the average loading rate. Accelerating premonitory slip was observed in these experiments and is a controlling factor in determining the conditions under which correlated events occur. In fact, some form of delayed failure is necessary to produce the observed correlations between simulated earthquake timing and characteristics of the periodic loading function. The transition from strongly correlated to weakly correlated model earthquake populations occurred when the amplitude of the periodic loading was approximately 0.05 to 0.1 MPa shear stress (0.03 to 0.06 MPa Coulomb failure function). Lower-amplitude oscillations produced progressively lower correlation levels. Correlations between static stress increases and earthquake aftershocks are found to degrade at similar stress levels. Typical stress variations due to Earth tides are only 0.001 to 0.004 MPa, so that the lack of correlation between Earth tides and earthquakes is also consistent with our findings. A simple extrapolation of our results suggests that approximately 1% of midcrustal earthquakes should be correlated with Earth tides. Triggered seismicity has been reported resulting from the passage of surface waves excited by the Landers earthquake. These transient waves had measured amplitudes in excess of 0.1 MPa at frequencies of 0.05 to 0.2 Hz in regions of notable seismicity increase. Similar stress oscillations in our laboratory experiments produced strongly correlated stick-slip events. We suggest that seemingly inconsistent natural observations of triggered seismicity and absence of tidal triggering indicate that failure is amplitude and frequency dependent. This is the expected result if, as in our laboratory experiments, the rheology of the Earth's crust permits delayed failure.

  16. Rotational-oscillational motions of the nonrigid Earth about the center of mass

    NASA Astrophysics Data System (ADS)

    Bondarenko, V. V.; Perepelkin, V. V.

    2009-10-01

    We use the model of a nearly axisymmetric viscoelastic rigid body to study perturbed rotational-oscillational motions of the Earth's pole. We point out that the Chandler component of oscillations is of celestial-mechanics nature and is caused by the gravitational-tidal actions of the Sun and the Moon. We analyze the pole oscillation excitation mechanism at a frequency close to the Chandler frequency and show that the undamped pole oscillations are caused by the resonance harmonic of the external perturbation at a frequency close to the free nutation frequency. We discuss whether it is possible to solve the problem of constructing a short-term forecast of the pole motion on the basis of a polynomial filter obtained by the least-squares method without taking into account small-scale oscillations caused by wide-band random factors of arbitrary physical nature. In the present paper, we perform numerical simulation of tidal inhomogeneities in the Earth's axial rotation. Attention is mainly paid to the analysis of day length variations on short time intervals with periods less than or equal to one year (interannual oscillations) and to their forecast.

  17. The frequency preference of neurons and synapses in a recurrent oscillatory network.

    PubMed

    Tseng, Hua-an; Martinez, Diana; Nadim, Farzan

    2014-09-17

    A variety of neurons and synapses shows a maximal response at a preferred frequency, generally considered to be important in shaping network activity. We are interested in whether all neurons and synapses in a recurrent oscillatory network can have preferred frequencies and, if so, whether these frequencies are the same or correlated, and whether they influence the network activity. We address this question using identified neurons in the pyloric network of the crab Cancer borealis. Previous work has shown that the pyloric pacemaker neurons exhibit membrane potential resonance whose resonance frequency is correlated with the network frequency. The follower lateral pyloric (LP) neuron makes reciprocally inhibitory synapses with the pacemakers. We find that LP shows resonance at a higher frequency than the pacemakers and the network frequency falls between the two. We also find that the reciprocal synapses between the pacemakers and LP have preferred frequencies but at significantly lower values. The preferred frequency of the LP to pacemaker synapse is correlated with the presynaptic preferred frequency, which is most pronounced when the peak voltage of the LP waveform is within the dynamic range of the synaptic activation curve and a shift in the activation curve by the modulatory neuropeptide proctolin shifts the frequency preference. Proctolin also changes the power of the LP neuron resonance without significantly changing the resonance frequency. These results indicate that different neuron types and synapses in a network may have distinct preferred frequencies, which are subject to neuromodulation and may interact to shape network oscillations. Copyright © 2014 the authors 0270-6474/14/3412933-13$15.00/0.

  18. Dissociation of frontal-midline delta-theta and posterior alpha oscillations: A mobile EEG study.

    PubMed

    Liang, Mingli; Starrett, Michael J; Ekstrom, Arne D

    2018-04-22

    Numerous reports have demonstrated low-frequency oscillations during navigation using invasive recordings in the hippocampus of both rats and human patients. Given evidence, in some cases, of low-frequency synchronization between midline cortex and hippocampus, it is also possible that low-frequency movement-related oscillations manifest in healthy human neocortex. However, this possibility remains largely unexplored, in part due to the difficulties of coupling free ambulation and effective scalp EEG recordings. In the current study, participants freely ambulated on an omnidirectional treadmill and explored an immersive virtual reality city rendered on a head-mounted display while undergoing simultaneous wireless scalp EEG recordings. We found that frontal-midline (FM) delta-theta (2-7.21 Hz) oscillations increased during movement compared to standing still periods, consistent with a role in navigation. In contrast, posterior alpha (8.32-12.76 Hz) oscillations were suppressed in the presence of visual input, independent of movement. Our findings suggest that FM delta-theta and posterior alpha oscillations arise at independent frequencies, under complementary behavioral conditions, and, at least for FM delta-theta oscillations, at independent recordings sites. Together, our findings support a double dissociation between movement-related FM delta-theta and resting-related posterior alpha oscillations. Our study thus provides novel evidence that FM delta-theta oscillations arise, in part, from real-world ambulation, and are functionally independent from posterior alpha oscillations. © 2018 Society for Psychophysiological Research.

  19. Optical distribution of local oscillators in future telecommunication satellite payloads

    NASA Astrophysics Data System (ADS)

    Benazet, Benoît; Sotom, Michel; Maignan, Michel; Berthon, Jacques

    2017-11-01

    The distribution of high spectral purity reference signals over optical fibre in future telecommunication satellite payloads is presented. Several types of applications are considered, including the distribution of a reference frequency at 10 MHz (Ultra-Stable Reference Oscillator) as well as the distribution of a radiofrequency oscillator around 800 MHz (Master Local Oscillator). The results of both experimental and theoretical studies are reported. In order to meet phase noise requirements for the USRO distribution, the use of an optimised receiver circuit based on an optically synchronised oscillator is investigated. Finally, the optical distribution of microwave local oscillators at frequencies exceeding 20 GHz is described. Such a scheme paves the way to more advanced sub-systems involving optical frequency-mixing and optical transmission of microwave signals, with applications to multiple-beam active antennas.

  20. High-frequency gamma oscillations coexist with low-frequency gamma oscillations in the rat visual cortex in vitro.

    PubMed

    Oke, Olaleke O; Magony, Andor; Anver, Himashi; Ward, Peter D; Jiruska, Premysl; Jefferys, John G R; Vreugdenhil, Martin

    2010-04-01

    Synchronization of neuronal activity in the visual cortex at low (30-70 Hz) and high gamma band frequencies (> 70 Hz) has been associated with distinct visual processes, but mechanisms underlying high-frequency gamma oscillations remain unknown. In rat visual cortex slices, kainate and carbachol induce high-frequency gamma oscillations (fast-gamma; peak frequency approximately 80 Hz at 37 degrees C) that can coexist with low-frequency gamma oscillations (slow-gamma; peak frequency approximately 50 Hz at 37 degrees C) in the same column. Current-source density analysis showed that fast-gamma was associated with rhythmic current sink-source sequences in layer III and slow-gamma with rhythmic current sink-source sequences in layer V. Fast-gamma and slow-gamma were not phase-locked. Slow-gamma power fluctuations were unrelated to fast-gamma power fluctuations, but were modulated by the phase of theta (3-8 Hz) oscillations generated in the deep layers. Fast-gamma was spatially less coherent than slow-gamma. Fast-gamma and slow-gamma were dependent on gamma-aminobutyric acid (GABA)(A) receptors, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors and gap-junctions, their frequencies were reduced by thiopental and were weakly dependent on cycle amplitude. Fast-gamma and slow-gamma power were differentially modulated by thiopental and adenosine A(1) receptor blockade, and their frequencies were differentially modulated by N-methyl-D-aspartate (NMDA) receptors, GluK1 subunit-containing receptors and persistent sodium currents. Our data indicate that fast-gamma and slow-gamma both depend on and are paced by recurrent inhibition, but have distinct pharmacological modulation profiles. The independent co-existence of fast-gamma and slow-gamma allows parallel processing of distinct aspects of vision and visual perception. The visual cortex slice provides a novel in vitro model to study cortical high-frequency gamma oscillations.

  1. Generation of a tunable environment for electrical oscillator systems.

    PubMed

    León-Montiel, R de J; Svozilík, J; Torres, Juan P

    2014-07-01

    Many physical, chemical, and biological systems can be modeled by means of random-frequency harmonic oscillator systems. Even though the noise-free evolution of harmonic oscillator systems can be easily implemented, the way to experimentally introduce, and control, noise effects due to a surrounding environment remains a subject of lively interest. Here, we experimentally demonstrate a setup that provides a unique tool to generate a fully tunable environment for classical electrical oscillator systems. We illustrate the operation of the setup by implementing the case of a damped random-frequency harmonic oscillator. The high degree of tunability and control of our scheme is demonstrated by gradually modifying the statistics of the oscillator's frequency fluctuations. This tunable system can readily be used to experimentally study interesting noise effects, such as noise-induced transitions in systems driven by multiplicative noise, and noise-induced transport, a phenomenon that takes place in quantum and classical coupled oscillator networks.

  2. Patients with Chronic Visceral Pain Show Sex-Related Alterations in Intrinsic Oscillations of the Resting Brain

    PubMed Central

    Hong, Jui-Yang; Kilpatrick, Lisa A.; Labus, Jennifer; Gupta, Arpana; Jiang, Zhiguo; Ashe-McNalley, Cody; Stains, Jean; Heendeniya, Nuwanthi; Ebrat, Bahar; Smith, Suzanne; Tillisch, Kirsten; Naliboff, Bruce

    2013-01-01

    Abnormal responses of the brain to delivered and expected aversive gut stimuli have been implicated in the pathophysiology of irritable bowel syndrome (IBS), a visceral pain syndrome occurring more commonly in women. Task-free resting-state functional magnetic resonance imaging (fMRI) can provide information about the dynamics of brain activity that may be involved in altered processing and/or modulation of visceral afferent signals. Fractional amplitude of low-frequency fluctuation is a measure of the power spectrum intensity of spontaneous brain oscillations. This approach was used here to identify differences in the resting-state activity of the human brain in IBS subjects compared with healthy controls (HCs) and to identify the role of sex-related differences. We found that both the female HCs and female IBS subjects had a frequency power distribution skewed toward high frequency to a greater extent in the amygdala and hippocampus compared with male subjects. In addition, female IBS subjects had a frequency power distribution skewed toward high frequency in the insula and toward low frequency in the sensorimotor cortex to a greater extent than male IBS subjects. Correlations were observed between resting-state blood oxygen level-dependent signal dynamics and some clinical symptom measures (e.g., abdominal discomfort). These findings provide the first insight into sex-related differences in IBS subjects compared with HCs using resting-state fMRI. PMID:23864686

  3. Separation control with fluidic oscillators in water

    NASA Astrophysics Data System (ADS)

    Schmidt, H.-J.; Woszidlo, R.; Nayeri, C. N.; Paschereit, C. O.

    2017-08-01

    The present study assesses the applicability of fluidic oscillators for separation control in water. The first part of this work evaluates the properties of the fluidic oscillators including frequency, cavitation effects, and exerted thrust. Derived from the governing internal dynamics, the oscillation frequency is found to scale directly with the jet's exit velocity and the size of the fluidic oscillator independent of the working fluid. Frequency data from various experiments collapse onto a single curve. The occurrence of cavitation is examined by visual inspection and hydrophone measurements. The oscillation frequency is not affected by cavitation because it does not occur inside the oscillators. The spectral information obtained with the hydrophone provide a reliable indicator for the onset of cavitation at the exit. The performance of the fluidic oscillators for separation control on a bluff body does not seem to be affected by the presence of cavitation. The thrust exerted by an array of fluidic oscillators with water as the working fluid is measured to be even larger than theoretically estimated values. The second part of the presented work compares the performance of fluidic oscillators for separation control in water with previous results in air. The array of fluidic oscillators is installed into the rear end of a bluff body model. The drag improvements based on force balance measurements agree well with previous wind tunnel experiments on the same model. The flow field is examined by pressure measurements and with particle image velocimetry. Similar performance and flow field characteristics are observed in both water and air.

  4. Twin peak high-frequency quasi-periodic oscillations as a spectral imprint of dual oscillation modes of accretion tori

    NASA Astrophysics Data System (ADS)

    Bakala, P.; Goluchová, K.; Török, G.; Šrámková, E.; Abramowicz, M. A.; Vincent, F. H.; Mazur, G. P.

    2015-09-01

    Context. High-frequency (millisecond) quasi-periodic oscillations (HF QPOs) are observed in the X-ray power-density spectra of several microquasars and low-mass X-ray binaries. Two distinct QPO peaks, so-called twin peak QPOs, are often detected simultaneously exhibiting their frequency ratio close or equal to 3:2. A widely discussed class of proposed QPOs models is based on oscillations of accretion toroidal structures orbiting in the close vicinity of black holes or neutron stars. Aims: Following the analytic theory and previous studies of observable spectral signatures, we aim to model the twin peak QPOs as a spectral imprint of specific dual oscillation regime defined by a combination of the lowest radial and vertical oscillation mode of slender tori. We consider the model of an optically thick slender accretion torus with constant specific angular momentum. We examined power spectra and fluorescent Kα iron line profiles for two different simulation setups with the mode frequency relations corresponding to the epicyclic resonance HF QPOs model and modified relativistic precession QPOs model. Methods: We used relativistic ray-tracing implemented in the parallel simulation code LSDplus. In the background of the Kerr spacetime geometry, we analyzed the influence of the distant observer inclination and the spin of the central compact object. Relativistic optical projection of the oscillating slender torus is illustrated by images in false colours related to the frequency shift. Results: We show that performed simulations yield power spectra with the pair of dominant peaks that correspond to the frequencies of radial and vertical oscillation modes and with the peak frequency ratio equal to the proper value 3:2 on a wide range of inclinations and spin values. We also discuss exceptional cases of a very low and very high inclination, as well as unstable high spin relativistic precession-like configurations that predict a constant frequency ratio equal to 1:2. We demonstrate a significant dependency of broadened Kα iron line profiles on the inclination of the distant observer. Conclusions: This study presents a further step towards the proper model of oscillating accretion tori producing HF QPOs. More realistic future simulations should be based on incorporating the resonant coupling of oscillation modes, the influence of torus opacity, and the pressure effects on the mode frequencies and the torus shape.

  5. Condensate oscillations in a Penrose tiling lattice

    NASA Astrophysics Data System (ADS)

    Akdeniz, Z.; Vignolo, P.

    2017-07-01

    We study the dynamics of a Bose-Einstein condensate subject to a particular Penrose tiling lattice. In such a lattice, the potential energy at each site depends on the neighbour sites, accordingly to the model introduced by Sutherland [16]. The Bose-Einstein wavepacket, initially at rest at the lattice symmetry center, is released. We observe a very complex time-evolution that strongly depends on the symmetry center (two choices are possible), on the potential energy landscape dispersion, and on the interaction strength. The condensate-width oscillates at different frequencies and we can identify large-frequency reshaping oscillations and low-frequency rescaling oscillations. We discuss in which conditions these oscillations are spatially bounded, denoting a self-trapping dynamics.

  6. Climatic controls of the interannual to decadal variability in Saudi Arabian dust activity: Towards the development of a seasonal prediction tool

    NASA Astrophysics Data System (ADS)

    Yu, Y.; Notaro, M.; Liu, Z.; Alkolibi, F.; Fadda, E.; Bakhrjy, F.

    2013-12-01

    Atmospheric dust significantly influences the climate system, as well as human life in Saudi Arabia. Skillful seasonal prediction of dust activity with climatic variables will help prevent some negative social impacts of dust storms. Yet, the climatic regulators on Saudi Arabian dust activity remain largely unaddressed. Remote sensing and station observations show consistent seasonal cycles in Saudi Arabian dust activity, which peaks in spring and summer. The climatic controls on springtime and summertime Saudi Arabian dust activity during 1975-2010 are studied using observational and reanalysis data. Empirical Orthogonal Function (EOF) of the observed Saudi Arabian dust storm frequency shows a dominant homogeneous pattern across the country, which has distinct interannual and decadal variations, as revealed by the power spectrum. Regression and correlation analyses reveal that Saudi Arabian dust activity is largely tied to precipitation on the Arabian Peninsula in spring and northwesterly (Shamal) wind in summer. On the seasonal-interannual time scale, warm El Niño-Southern Oscillation (ENSO) phase (El Niño) in winter-to-spring inhibits spring dust activity by increasing the precipitation over the Rub'al Khali Desert, a major dust source region on the southern Arabian Peninsula; warm ENSO and warm Indian Ocean Basin Mode (IOBM) in winter-to-spring favor less summer dust activity by producing anomalously low sea-level pressure over eastern north Africa and Arabian Peninsula, which leads to the reduced Shamal wind speed. The decadal variation in dust activity is likely associated with the Atlantic Multidecadal Oscillation (AMO), which impacts Sahel rainfall and North African dust, and likely dust transport to Saudi Arabia. The Pacific Decadal Oscillation (PDO) and tropical Indian Ocean SST also have influence on the decadal variation in Saudi Arabian dust activity, by altering precipitation over the Arabian Peninsula and summer Shamal wind speed. Using eastern tropical Pacific SST as the high-frequency predictor and antecedent accumulated precipitation over the Arabian Peninsula and North Africa as low-frequency predictors, the predicted seasonal dust activity over Saudi Arabia is well correlated with the original time series (correlation above 0.6).

  7. Plasma oscillations in a 6-kW magnetically shielded Hall thruster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jorns, Benjamin A., E-mail: benjamin.a.jorns@jpl.nasa.gov; Hofer, Richard R.

    2014-05-15

    Plasma oscillations from 0–100 kHz in a 6-kW magnetically shielded Hall thruster are experimentally characterized with a high-speed, optical camera. Two modes are identified at 7–12 kHz and 70–90 kHz. The low frequency mode is found to be azimuthally uniform across the thruster face, while the high frequency oscillation is peaked close to the centerline-mounted cathode with an m = 1 azimuthal dependence. An analysis of these results in the context of wave-based theory suggests that the low frequency wave is the breathing mode oscillation, while the higher frequency mode is gradient-driven. The effect of these oscillations on thruster operation is examined through an analysismore » of thruster discharge current and a comparison with published observations from an unshielded variant of the thruster. Most notably, it is found that although the oscillation spectra of the two thrusters are different, they exhibit nearly identical steady-state behavior.« less

  8. A wide-range variable-frequency resonant tunneling diode oscillator using a variable resonator suitable for simple MEMS process

    NASA Astrophysics Data System (ADS)

    Yamashita, Takashi; Nakano, Daisuke; Mori, Masayuki; Maezawa, Koichi

    2018-04-01

    A resonant tunneling diode oscillator having a wide frequency variation range based on a novel MEMS resonator was proposed, which exploits the change in the signal propagation velocity on a coplanar waveguide according to a movable ground plane. First, we discussed the velocity modulation mechanism, and clarified the importance of the dielectric constant of the substrate. Then, a prototype device oscillating in a 10 to 20 GHz frequency range was fabricated to demonstrate the basic operation. A large and continuous increase in the oscillation frequency of about two times was achieved with this device. This is promising for various applications including THz spectroscopy.

  9. Detection of frequency-mode-shift during thermoacoustic combustion oscillations in a staged aircraft engine model combustor

    NASA Astrophysics Data System (ADS)

    Kobayashi, Hiroaki; Gotoda, Hiroshi; Tachibana, Shigeru; Yoshida, Seiji

    2017-12-01

    We conduct an experimental study using time series analysis based on symbolic dynamics to detect a precursor of frequency-mode-shift during thermoacoustic combustion oscillations in a staged aircraft engine model combustor. With increasing amount of the main fuel, a significant shift in the dominant frequency-mode occurs in noisy periodic dynamics, leading to a notable increase in oscillation amplitudes. The sustainment of noisy periodic dynamics during thermoacoustic combustion oscillations is clearly shown by the multiscale complexity-entropy causality plane in terms of statistical complexity. A modified version of the permutation entropy allows us to detect a precursor of the frequency-mode-shift before the amplification of pressure fluctuations.

  10. Rate control and quality assurance during rhythmic force tracking.

    PubMed

    Huang, Cheng-Ya; Su, Jyong-Huei; Hwang, Ing-Shiou

    2014-02-01

    Movement characteristics can be coded in the single neurons or in the summed activity of neural populations. However, whether neural oscillations are conditional to the frequency demand and task quality of rhythmic force regulation is still unclear. This study was undertaken to investigate EEG dynamics and behavior correlates during force-tracking at different target rates. Fourteen healthy volunteers conducted load-varying isometric abduction of the index finger by coupling the force output to sinusoidal targets at 0.5 Hz, 1.0 Hz, and 2.0 Hz. Our results showed that frequency demand significantly affected EEG delta oscillation (1-4 Hz) in the C3, CP3, CPz, and CP4 electrodes, with the greatest delta power and lowest delta peak around 1.5 Hz for slower tracking at 0.5 Hz. Those who had superior tracking congruency also manifested enhanced alpha oscillation (8-12 Hz). Alpha rhythms of the skilled performers during slow tracking spread through the whole target cycle, except for the phase of direction changes. However, the alpha rhythms centered at the mid phase of a target cycle with increasing target rate. In conclusion, our findings clearly suggest two advanced roles of cortical oscillation in rhythmic force regulation. Rate-dependent delta oscillation involves a paradigm shift in force control under different time scales. Phasic organization of alpha rhythms during rhythmic force tracking is related to behavioral success underlying the selective use of bimodal controls (feedback and feedforward processes) and the timing of attentional focus on the target's peak velocity. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. GABAergic modulation of visual gamma and alpha oscillations and its consequences for working memory performance.

    PubMed

    Lozano-Soldevilla, Diego; ter Huurne, Niels; Cools, Roshan; Jensen, Ole

    2014-12-15

    Impressive in vitro research in rodents and computational modeling has uncovered the core mechanisms responsible for generating neuronal oscillations. In particular, GABAergic interneurons play a crucial role for synchronizing neural populations. Do these mechanistic principles apply to human oscillations associated with function? To address this, we recorded ongoing brain activity using magnetoencephalography (MEG) in healthy human subjects participating in a double-blind pharmacological study receiving placebo, 0.5 mg and 1.5 mg of lorazepam (LZP; a benzodiazepine upregulating GABAergic conductance). Participants performed a demanding visuospatial working memory (WM) task. We found that occipital gamma power associated with WM recognition increased with LZP dosage. Importantly, the frequency of the gamma activity decreased with dosage, as predicted by models derived from the rat hippocampus. A regionally specific gamma increase correlated with the drug-related performance decrease. Despite the system-wide pharmacological intervention, gamma power drug modulations were specific to visual cortex: sensorimotor gamma power and frequency during button presses remained unaffected. In contrast, occipital alpha power modulations during the delay interval decreased parametrically with drug dosage, predicting performance impairment. Consistent with alpha oscillations reflecting functional inhibition, LZP affected alpha power strongly in early visual regions not required for the task demonstrating a regional specific occipital impairment. GABAergic interneurons are strongly implicated in the generation of gamma and alpha oscillations in human occipital cortex where drug-induced power modulations predicted WM performance. Our findings bring us an important step closer to linking neuronal dynamics to behavior by embracing established animal models. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. An Evaluation of Teleconnections Over the United States in an Ensemble of AMIP Simulations with the MERRA-2 Configuration of the GEOS Atmospheric Model

    NASA Technical Reports Server (NTRS)

    Collow, Allison B. Marquardt; Mahanama, Sarith P.; Bosilovich, Michael G.; Koster, Randal D.; Schubert, Siegfried D.

    2017-01-01

    The atmospheric general circulation model that is used in NASA's Modern Era Retrospective Analysis for Research and Applications Version 2 (MERRA-2) is evaluated with respect to the relationship between large-scale teleconnection patterns and daily temperature and precipitation over the United States (US) using a ten-member ensemble of simulations, referred to as M2AMIP. A focus is placed on four teleconnection patterns that are known to influence weather and climate in the US: El Nino Southern Oscillation, the Pacific Decadal Oscillation, the North Atlantic Oscillation, and the Pacific-North American Pattern. The monthly and seasonal indices associated with the patterns are correlated with daily temperature and precipitation statistics including: (i) monthly mean 2 m temperature and precipitation, (ii) the frequency of extreme temperature events at the 90th, 95th, and 99th percentiles, and (iii) the frequency and intensity of extreme precipitation events classified at the 90th, 95th, and 99th percentiles.Correlations obtained with M2AMIP data and thus the strength of teleconnections in the free-running model are evaluated through comparison against corresponding correlations computed from observations and from MERRA-2. Overall, the strongest teleconnections in all datasets occur during the winter and coincide with the largest agreement between the observations, MERRA-2, and M2AMIP. When M2AMIP does capture the correlation seen in observations, there is a tendency for the spatial extent to be exaggerated. The weakest agreement between the data sources, for all teleconnection patterns, is in the correlation with extreme precipitation; however there are discrepancies between the datasets in the number of days with at least 1 mm of precipitation: M2AMIP has too few days with precipitation in the Northwest and the Northern Great Plains and too many days in the Northeast. In JJA, M2AMIP has too few days with precipitation in the western two-thirds of the country and too many days with precipitation along the east coast.

  13. S-band SBAW microwave source, phase 2

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Results of aging experiments on 1.072 GHz SBAW oscillators are discussed as well as the design, fabrication and test of 2.143 GHz SBAW delay lines. Two design approaches were implemented. The third harmonic transducer on 36 deg rotated Y cut quartz proved to be the most useful design, whereas the fifth harmonic transducer on - 50 5 deg rotated Y cut quartz suffered from high insertion loss and poor sidelobe rejection. The construction and characterization of the 2 GHz SBAW oscillator are described. Phase noise, frequency dependence on temperature, and 6-month aging were measured. Some SAW and SBAW oscillators were compared as were both the 1 and 2 GHz oscillators. The 2 GHz SBAW oscillator showed significant improvement in phase noise and temperature stability over the 2 GHz SAW oscillator developed in previous NASA programs. A technique to produce SBAW delay lines of different frequencies from a single mask is examined. The delay lines were incorporated into oscillator circuits to demonstrate the ability to select the frequency output of the SBAW oscillator.

  14. Transverse distribution of beam current oscillations of a 14 GHz electron cyclotron resonance ion source.

    PubMed

    Tarvainen, O; Toivanen, V; Komppula, J; Kalvas, T; Koivisto, H

    2014-02-01

    The temporal stability of oxygen ion beams has been studied with the 14 GHz A-ECR at JYFL (University of Jyvaskyla, Department of Physics). A sector Faraday cup was employed to measure the distribution of the beam current oscillations across the beam profile. The spatial and temporal characteristics of two different oscillation "modes" often observed with the JYFL 14 GHz ECRIS are discussed. It was observed that the low frequency oscillations below 200 Hz are distributed almost uniformly. In the high frequency oscillation "mode," with frequencies >300 Hz at the core of the beam, carrying most of the current, oscillates with smaller amplitude than the peripheral parts of the beam. The results help to explain differences observed between the two oscillation modes in terms of the transport efficiency through the JYFL K-130 cyclotron. The dependence of the oscillation pattern on ion source parameters is a strong indication that the mechanisms driving the fluctuations are plasma effects.

  15. Exploring the time-frequency content of high frequency oscillations for automated identification of seizure onset zone in epilepsy.

    PubMed

    Liu, Su; Sha, Zhiyi; Sencer, Altay; Aydoseli, Aydin; Bebek, Nerse; Abosch, Aviva; Henry, Thomas; Gurses, Candan; Ince, Nuri Firat

    2016-04-01

    High frequency oscillations (HFOs) in intracranial electroencephalography (iEEG) recordings are considered as promising clinical biomarkers of epileptogenic regions in the brain. The aim of this study is to improve and automatize the detection of HFOs by exploring the time-frequency content of iEEG and to investigate the seizure onset zone (SOZ) detection accuracy during the sleep, awake and pre-ictal states in patients with epilepsy, for the purpose of assisting the localization of SOZ in clinical practice. Ten-minute iEEG segments were defined during different states in eight patients with refractory epilepsy. A three-stage algorithm was implemented to detect HFOs in these segments. First, an amplitude based initial detection threshold was used to generate a large pool of HFO candidates. Then distinguishing features were extracted from the time and time-frequency domain of the raw iEEG and used with a Gaussian mixture model clustering to isolate HFO events from other activities. The spatial distribution of HFO clusters was correlated with the seizure onset channels identified by neurologists in seven patient with good surgical outcome. The overlapping rates of localized channels and seizure onset locations were high in all states. The best result was obtained using the iEEG data during sleep, achieving a sensitivity of 81%, and a specificity of 96%. The channels with maximum number of HFOs identified epileptogenic areas where the seizures occurred more frequently. The current study was conducted using iEEG data collected in realistic clinical conditions without channel pre-exclusion. HFOs were investigated with novel features extracted from the entire frequency band, and were correlated with SOZ in different states. The results indicate that automatic HFO detection with unsupervised clustering methods exploring the time-frequency content of raw iEEG can be efficiently used to identify the epileptogenic zone with an accurate and efficient manner.

  16. WIDE BAND REGENERATIVE FREQUENCY DIVIDER AND MULTIPLIER

    DOEpatents

    Laine, E.F.

    1959-11-17

    A regenerative frequency divider and multiplier having wide band input characteristics is presented. The circuit produces output oscillations having frequencies related by a fixed ratio to input oscillations over a wide band of frequencies. In accomplishing this end, the divider-multiplier includes a wide band input circuit coupled by mixer means to a wide band output circuit having a pass band related by a fixed ratio to that of the input circuit. A regenerative feedback circuit derives a fixed frequency ratio feedback signal from the output circuit and applies same to the mixer means in proper phase relation to sustain fixed frequency ratio oscillations in the output circuit.

  17. Dynamic cerebral autoregulation during repeated squat-stand maneuvers

    PubMed Central

    Claassen, Jurgen A. H. R.; Levine, Benjamin D.; Zhang, Rong

    2009-01-01

    Transfer function analysis of spontaneous oscillations in blood pressure (BP) and cerebral blood flow (CBF) can quantify the dynamic relationship between BP and CBF. However, such oscillation amplitudes are often small and of questionable clinical significance, vary substantially, and cannot be controlled. At the very low frequencies (<0.07 Hz), coherence between BP and CBF often is low (<0.50) and their causal relationship is debated. Eight healthy subjects performed repeated squat-stand maneuvers to induce large oscillations in BP at frequencies of 0.025 and 0.05 Hz (very low frequency) and 0.1 Hz (low frequency), respectively. BP (Finapres), CBF velocity (CBFV; transcranial Doppler), and end-tidal CO2 (capnography) were monitored. Spectral analysis was used to quantify oscillations in BP and CBFV and to estimate transfer function phase, gain, and coherence. Compared with spontaneous oscillations, induced oscillations had higher coherence [mean 0.8 (SD 0.11); >0.5 in all subjects at all frequencies] and lower variability in phase estimates. However, gain estimates remained unchanged. Under both conditions, the “high-pass filter” characteristics of dynamic autoregulation were observed. In conclusion, using repeated squat-stand maneuvers, we were able to study dynamic cerebral autoregulation in the low frequencies under conditions of hemodynamically strong and causally related oscillations in BP and CBFV. This not only enhances the confidence of transfer function analysis as indicated by high coherence and improved phase estimation but also strengthens the clinical relevance of this method as induced oscillations in BP and CBFV mimic those associated with postural changes in daily life. PMID:18974368

  18. Effect of temperature oscillation on thermal characteristics of an aluminum thin film

    NASA Astrophysics Data System (ADS)

    Ali, H.; Yilbas, B. S.

    2014-12-01

    Energy transport in aluminum thin film is examined due to temperature disturbance at the film edge. Thermal separation of electron and lattice systems is considered in the analysis, and temperature variation in each sub-system is formulated. The transient analysis of frequency-dependent and frequency-independent phonon radiative transport incorporating electron-phonon coupling is carried out in the thin film. The dispersion relations of aluminum are used in the frequency-dependent analysis. Temperature at one edge of the film is oscillated at various frequencies, and temporal response of phonon intensity distribution in the film is predicted numerically using the discrete ordinate method. To assess the phonon transport characteristics, equivalent equilibrium temperature is introduced. It is found that equivalent equilibrium temperature in the electron and lattice sub-systems oscillates due to temperature oscillation at the film edge. The amplitude of temperature oscillation reduces as the distance along the film thickness increases toward the low-temperature edge of the film. Equivalent equilibrium temperature attains lower values for the frequency-dependent solution of the phonon transport equation than that corresponding to frequency-independent solution.

  19. Velocity correlations and spatial dependencies between neighbors in a unidirectional flow of pedestrians

    NASA Astrophysics Data System (ADS)

    Porzycki, Jakub; WÄ s, Jarosław; Hedayatifar, Leila; Hassanibesheli, Forough; Kułakowski, Krzysztof

    2017-08-01

    The aim of the paper is an analysis of self-organization patterns observed in the unidirectional flow of pedestrians. On the basis of experimental data from Zhang et al. [J. Zhang et al., J. Stat. Mech. (2011) P06004, 10.1088/1742-5468/2011/06/P06004], we analyze the mutual positions and velocity correlations between pedestrians when walking along a corridor. The angular and spatial dependencies of the mutual positions reveal a spatial structure that remains stable during the crowd motion. This structure differs depending on the value of n , for the consecutive n th -nearest-neighbor position set. The preferred position for the first-nearest neighbor is on the side of the pedestrian, while for further neighbors, this preference shifts to the axis of movement. The velocity correlations vary with the angle formed by the pair of neighboring pedestrians and the direction of motion and with the time delay between pedestrians' movements. The delay dependence of the correlations shows characteristic oscillations, produced by the velocity oscillations when striding; however, a filtering of the main frequency of individual striding out reduces the oscillations only partially. We conclude that pedestrians select their path directions so as to evade the necessity of continuously adjusting their speed to their neighbors'. They try to keep a given distance, but follow the person in front of them, as well as accepting and observing pedestrians on their sides. Additionally, we show an empirical example that illustrates the shape of a pedestrian's personal space during movement.

  20. Comparing performance of three oscillating positive expiratory pressure devices at similar amplitude and frequencies of oscillations on displacement of mucus inside trachea during cough.

    PubMed

    Ragavan, Anpalaki J

    2012-03-13

    Performance of Flutter® (Axcan Scandipharm Inc, Birmingham, AL), Acapella® (Smiths Medicals Inc, Rockland, MA) and Quake® (Thayer Medical, Tucson, AZ) were compared at similar frequencies and amplitudes of oscillations at nine angles of the device in clearing simulated mucus inside a tracheal model (trachea) oriented at three angles with or without simulated constrictions in airway upstream of trachea. Displacement of 0.4mL of simulated mucus prepared with viscoelastic properties similar to healthy individuals (syrup-like) or patients with COPD (gel-like) using locust bean gum(LBG) solution (0.38g LBG in 100mL water) cross-linked with 3mL or 12mL borax solution (0.02 molar), respectively were measured inside trachea during coughs of 300ms at low cough velocity (15±0.5m/s) generated using a computer controlled solenoid valve. Oscillations were superimposed on cough by connecting the oscillator device to the outlet of the trachea. Frequency and amplitude of oscillations generated by Quake and Acapella and resulting mucus displacement were independent of angle of oscillator, while amplitude of oscillations and resulting mucus displacement generated by Flutter, increased up to 30o upward and 20o downward angles of Flutter from horizontal but decreased significantly thereafter. Displacement with Quake increased significantly with frequencies of oscillations up to 25 Hz and decreased thereafter but increased with amplitudes of oscillations up to 22±4.7 m/s. Quake showed significantly larger displacements than Flutter and Acapella at equal frequencies and amplitudes (p<0.05). Displacements were significantly larger with trachea positioned 30o upwards than horizontal or 20o downwards (p<0.0001). Displacement was the greatest for gel-like mucus than syrup-like (p<0.0001). Airway constrictions upstream resulted in enhanced displacement of mucus (p<0.0001). Mucus clearance can be significantly enhanced by coughing through oscillating positive expiratory devices that generate high amplitude oscillations at moderate frequencies, increasing frontal depths of mucus facing airflow and slightly increasing resistance to airflow in airways in COPD patients.

  1. Amplitude mode oscillations in pump-probe photoemission spectra from a d -wave superconductor

    NASA Astrophysics Data System (ADS)

    Nosarzewski, B.; Moritz, B.; Freericks, J. K.; Kemper, A. F.; Devereaux, T. P.

    2017-11-01

    Recent developments in the techniques of ultrafast pump-probe photoemission have made possible the search for collective modes in strongly correlated systems out of equilibrium. Including inelastic scattering processes and a retarded interaction, we simulate time- and angle-resolved photoemission spectroscopy (trARPES) to study the amplitude mode of a d -wave superconductor, a collective mode excited through the nonlinear light-matter coupling to the pump pulse. We find that the amplitude mode oscillations of the d -wave order parameter occur in phase at a single frequency that is twice the quasi-steady-state maximum gap size after pumping. We comment on the necessary conditions for detecting the amplitude mode in trARPES experiments.

  2. Brain rhythms and neural syntax: implications for efficient coding of cognitive content and neuropsychiatric disease.

    PubMed Central

    Buzsáki, György; Watson, Brendon O.

    2012-01-01

    The perpetual activity of the cerebral cortex is largely supported by the variety of oscillations the brain generates, spanning a number of frequencies and anatomical locations, as well as behavioral correlates. First, we review findings from animal studies showing that most forms of brain rhythms are inhibition-based, producing rhythmic volleys of inhibitory inputs to principal cell populations, thereby providing alternating temporal windows of relatively reduced and enhanced excitability in neuronal networks. These inhibition-based mechanisms offer natural temporal frames to group or “chunk” neuronal activity into cell assemblies and sequences of assemblies, with more complex multi-oscillation interactions creating syntactical rules for the effective exchange of information among cortical networks. We then review recent studies in human psychiatric patients demonstrating a variety alterations in neural oscillations across all major psychiatric diseases, and suggest possible future research directions and treatment approaches based on the fundamental properties of brain rhythms. PMID:23393413

  3. Modeling high-order synchronization epochs and transitions in the cardiovascular system

    NASA Astrophysics Data System (ADS)

    García-Álvarez, David; Bahraminasab, Alireza; Stefanovska, Aneta; McClintock, Peter V. E.

    2007-12-01

    We study a system consisting of two coupled phase oscillators in the presence of noise. This system is used as a model for the cardiorespiratory interaction in wakefulness and anaesthesia. We show that longrange correlated noise produces transitions between epochs with different n:m synchronisation ratios, as observed in the cardiovascular system. Also, we see that, the smaller the noise (specially the one acting on the slower oscillator), the bigger the synchronisation time, exactly as happens in anaesthesia compared with wakefulness. The dependence of the synchronisation time on the couplings, in the presence of noise, is studied; such dependence is softened by low-frequency noise. We show that the coupling from the slow oscillator to the fast one (respiration to heart) plays a more important role in synchronisation. Finally, we see that the isolines with same synchronisation time seem to be a linear combination of the two couplings.

  4. Plasma fluctuations in a Kaufman thruster. [root mean square magnitude, spectra and cross correlation

    NASA Technical Reports Server (NTRS)

    Serafini, J. S.; Terdan, F. F.

    1973-01-01

    Measurements of the RMS magnitude, spectra and cross-correlations for the fluctuations in the beam, discharge and neutralizer keeper currents are presented for a 30-cm diameter dished grid ion thrustor for a range of magnetic baffle currents and up to 2.0 amperes beam current. The ratio of RMS to mean ion beam current varied from 0.04 to 0.23. The spectra of the amplitudes of the beam and discharge current fluctuations were taken up to 9 MHz and show that the predominant amplitudes occur at frequencies of 10 kHz or below. The fall-off with increasing frequency is rapid. Frequencies above 100 kHz the spectral levels are 45 kb or more below the maximum peak amplitudes. The cross-correlations revealed the ion beam fluctuations to have large radial and axial scales which implied that the beam fluctuates as a whole or 'in-phase.' The cross-correlations of the beam and neutralizer keeper current fluctuations indicated the neutralizer contributions to the beam fluctuations to be small, but not negligible. The mode of operation of the thrustor (values of beam and magnetic baffle currents) was significant in determining the RMS magnitude and spectral shape of the beam fluctuations. The major oscillations were not found to be directly dependent on the power conditioner inverter frequencies.

  5. Say hello to the DSO

    NASA Astrophysics Data System (ADS)

    Pate, G.; Roberts, T.

    1981-05-01

    In the 2-to-10 GHz frequency range, the dielectrically stabilized oscillators (DSOs) with their small size, simple construction, and modest bias requirements, have advantages over cavity-stabilized oscillators (CSOs) and crystal-controlled multiplier chains (XCOs). Commercially available DSOs consist of a transistor oscillator locked to some frequency by a resonant disk of dielectric material. The disk is coupled to a microstrip line at the output of the oscillator. The stability of a DSO lies between that of a crystal-controlled oscillator and that of a cavity-stabilized oscillator. Dielectrically stabilized oscillators, built with nine basic parts and few solder joints, can be expected to be much more reliable than a CSO or XCO.

  6. Frequency comb based on a narrowband Yb-fiber oscillator: pre-chirp management for self-referenced carrier envelope offset frequency stabilization.

    PubMed

    Lim, Jinkang; Chen, Hung-Wen; Chang, Guoqing; Kärtner, Franz X

    2013-02-25

    Laser frequency combs are normally based on mode-locked oscillators emitting ultrashort pulses of ~100-fs or shorter. In this paper, we present a self-referenced frequency comb based on a narrowband (5-nm bandwidth corresponding to 415-fs transform-limited pulses) Yb-fiber oscillator with a repetition rate of 280 MHz. We employ a nonlinear Yb-fiber amplifier to both amplify the narrowband pulses and broaden their optical spectrum. To optimize the carrier envelope offset frequency (fCEO), we optimize the nonlinear pulse amplification by pre-chirping the pulses at the amplifier input. An optimum negative pre-chirp exists, which produces a signal-to-noise ratio of 35 dB (100 kHz resolution bandwidth) for the detected fCEO. We phase stabilize the fCEO using a feed-forward method, resulting in 0.64-rad (integrated from 1 Hz to 10 MHz) phase noise for the in-loop error signal. This work demonstrates the feasibility of implementing frequency combs from a narrowband oscillator, which is of particular importance for realizing large line-spacing frequency combs based on multi-GHz oscillators usually emitting long (>200 fs) pulses.

  7. Direct EPR irradiation of a sample using a quartz oscillator operating at 250 MHz for EPR measurements.

    PubMed

    Yokoyama, Hidekatsu

    2012-01-01

    Direct irradiation of a sample using a quartz oscillator operating at 250 MHz was performed for EPR measurements. Because a quartz oscillator is a frequency fixed oscillator, the operating frequency of an EPR resonator (loop-gap type) was tuned to that of the quartz oscillator by using a single-turn coil with a varactor diode attached (frequency shift coil). Because the frequency shift coil was mobile, the distance between the EPR resonator and the coil could be changed. Coarse control of the resonant frequency was achieved by changing this distance mechanically, while fine frequency control was implemented by changing the capacitance of the varactor electrically. In this condition, EPR measurements of a phantom (comprised of agar with a nitroxide radical and physiological saline solution) were made. To compare the presented method with a conventional method, the EPR measurements were also done by using a synthesizer at the same EPR frequency. In the conventional method, the noise level increased at high irradiation power. Because such an increase in the noise was not observed in the presented method, high sensitivity was obtained at high irradiation power. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. An integrated low phase noise radiation-pressure-driven optomechanical oscillator chipset

    PubMed Central

    Luan, Xingsheng; Huang, Yongjun; Li, Ying; McMillan, James F.; Zheng, Jiangjun; Huang, Shu-Wei; Hsieh, Pin-Chun; Gu, Tingyi; Wang, Di; Hati, Archita; Howe, David A.; Wen, Guangjun; Yu, Mingbin; Lo, Guoqiang; Kwong, Dim-Lee; Wong, Chee Wei

    2014-01-01

    High-quality frequency references are the cornerstones in position, navigation and timing applications of both scientific and commercial domains. Optomechanical oscillators, with direct coupling to continuous-wave light and non-material-limited f × Q product, are long regarded as a potential platform for frequency reference in radio-frequency-photonic architectures. However, one major challenge is the compatibility with standard CMOS fabrication processes while maintaining optomechanical high quality performance. Here we demonstrate the monolithic integration of photonic crystal optomechanical oscillators and on-chip high speed Ge detectors based on the silicon CMOS platform. With the generation of both high harmonics (up to 59th order) and subharmonics (down to 1/4), our chipset provides multiple frequency tones for applications in both frequency multipliers and dividers. The phase noise is measured down to −125 dBc/Hz at 10 kHz offset at ~400 μW dropped-in powers, one of the lowest noise optomechanical oscillators to date and in room-temperature and atmospheric non-vacuum operating conditions. These characteristics enable optomechanical oscillators as a frequency reference platform for radio-frequency-photonic information processing. PMID:25354711

  9. Direct reading inductance meter

    NASA Technical Reports Server (NTRS)

    Kolby, R. B. (Inventor)

    1977-01-01

    A direct reading inductance meter comprised of a crystal oscillator and an LC tuned oscillator is presented. The oscillators function respectively to generate a reference frequency, f(r), and to generate an initial frequency, f(0), which when mixed produce a difference equal to zero. Upon connecting an inductor of small unknown value in the LC circuit to change its resonant frequency to f(x), a difference frequency (f(r)-f(x)) is produced that is very nearly a linear function of the inductance of the inductor. The difference frequency is measured and displayed on a linear scale in units of inductance.

  10. High-frequency sarcomeric auto-oscillations induced by heating in living neonatal cardiomyocytes of the rat

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shintani, Seine A.; Oyama, Kotaro; Fukuda, Norio, E-mail: noriof@jikei.ac.jp

    2015-02-06

    Highlights: • We tested the effects of infra-red laser irradiation on cardiac sarcomere dynamics. • A rise in temperature (>∼38 °C) induced high-frequency sarcomeric auto-oscillations. • These oscillations occurred with and without blockade of intracellular Ca{sup 2+} stores. • Cardiac sarcomeres can play a role as a temperature-dependent rhythm generator. - Abstract: In the present study, we investigated the effects of infra-red laser irradiation on sarcomere dynamics in living neonatal cardiomyocytes of the rat. A rapid increase in temperature to >∼38 °C induced [Ca{sup 2+}]{sub i}-independent high-frequency (∼5–10 Hz) sarcomeric auto-oscillations (Hyperthermal Sarcomeric Oscillations; HSOs). In myocytes with the intactmore » sarcoplasmic reticular functions, HSOs coexisted with [Ca{sup 2+}]{sub i}-dependent spontaneous beating in the same sarcomeres, with markedly varying frequencies (∼10 and ∼1 Hz for the former and latter, respectively). HSOs likewise occurred following blockade of the sarcoplasmic reticular functions, with the amplitude becoming larger and the frequency lower in a time-dependent manner. The present findings suggest that in the mammalian heart, sarcomeres spontaneously oscillate at higher frequencies than the sinus rhythm at temperatures slightly above the physiologically relevant levels.« less

  11. Low-noise correlation measurements based on software-defined-radio receivers and cooled microwave amplifiers.

    PubMed

    Nieminen, Teemu; Lähteenmäki, Pasi; Tan, Zhenbing; Cox, Daniel; Hakonen, Pertti J

    2016-11-01

    We present a microwave correlation measurement system based on two low-cost USB-connected software defined radio dongles modified to operate as coherent receivers by using a common local oscillator. Existing software is used to obtain I/Q samples from both dongles simultaneously at a software tunable frequency. To achieve low noise, we introduce an easy low-noise solution for cryogenic amplification at 600-900 MHz based on single discrete HEMT with 21 dB gain and 7 K noise temperature. In addition, we discuss the quantization effects in a digital correlation measurement and determination of optimal integration time by applying Allan deviation analysis.

  12. Continuous quantum measurement with independent detector cross correlations.

    PubMed

    Jordan, Andrew N; Büttiker, Markus

    2005-11-25

    We investigate the advantages of using two independent, linear detectors for continuous quantum measurement. For single-shot measurement, the detection process may be quantum limited if the detectors are twins. For weak continuous measurement, cross correlations allow a violation of the Korotkov-Averin bound for the detector's signal-to-noise ratio. The joint weak measurement of noncommuting observables is also investigated, and we find the cross correlation changes sign as a function of frequency, reflecting a crossover from incoherent relaxation to coherent, out of phase oscillations. Our results are applied to a double quantum-dot charge qubit, simultaneously measured by two quantum point contacts.

  13. Voluntary reduction of force variability via modulation of low-frequency oscillations.

    PubMed

    Park, Seoung Hoon; Casamento-Moran, Agostina; Yacoubi, Basma; Christou, Evangelos A

    2017-09-01

    Visual feedback can influence the force output by changing the power in frequencies below 1 Hz. However, it remains unknown whether visual guidance can help an individual reduce force variability voluntarily. The purpose of this study, therefore, was to determine whether an individual can voluntarily reduce force variability during constant contractions with visual guidance, and whether this reduction is associated with a decrease in the power of low-frequency oscillations (0-1 Hz) in force and muscle activity. Twenty young adults (27.6 ± 3.4 years) matched a force target of 15% MVC (maximal voluntary contraction) with ankle dorsiflexion. Participants performed six visually unrestricted contractions, from which we selected the trial with the least variability. Following, participants performed six visually guided contractions and were encouraged to reduce their force variability within two guidelines (±1 SD of the least variable unrestricted trial). Participants decreased the SD of force by 45% (P < 0.001) during the guided condition, without changing mean force (P > 0.2). The decrease in force variability was associated with decreased low-frequency oscillations (0-1 Hz) in force (R 2  = 0.59), which was associated with decreased low-frequency oscillations in EMG bursts (R 2  = 0.35). The reduction in low-frequency oscillations in EMG burst was positively associated with power in the interference EMG from 35 to 60 Hz (R 2  = 0.47). In conclusion, voluntary reduction of force variability is associated with decreased low-frequency oscillations in EMG bursts and consequently force output. We provide novel evidence that visual guidance allows healthy young adults to reduce force variability voluntarily likely by adjusting the low-frequency oscillations in the neural drive.

  14. Nature's Autonomous Oscillators

    NASA Technical Reports Server (NTRS)

    Mayr, H. G.; Yee, J.-H.; Mayr, M.; Schnetzler, R.

    2012-01-01

    Nonlinearity is required to produce autonomous oscillations without external time dependent source, and an example is the pendulum clock. The escapement mechanism of the clock imparts an impulse for each swing direction, which keeps the pendulum oscillating at the resonance frequency. Among nature's observed autonomous oscillators, examples are the quasi-biennial oscillation and bimonthly oscillation of the Earth atmosphere, and the 22-year solar oscillation. The oscillations have been simulated in numerical models without external time dependent source, and in Section 2 we summarize the results. Specifically, we shall discuss the nonlinearities that are involved in generating the oscillations, and the processes that produce the periodicities. In biology, insects have flight muscles, which function autonomously with wing frequencies that far exceed the animals' neural capacity; Stretch-activation of muscle contraction is the mechanism that produces the high frequency oscillation of insect flight, discussed in Section 3. The same mechanism is also invoked to explain the functioning of the cardiac muscle. In Section 4, we present a tutorial review of the cardio-vascular system, heart anatomy, and muscle cell physiology, leading up to Starling's Law of the Heart, which supports our notion that the human heart is also a nonlinear oscillator. In Section 5, we offer a broad perspective of the tenuous links between the fluid dynamical oscillators and the human heart physiology.

  15. High frequency oscillations are associated with cognitive processing in human recognition memory.

    PubMed

    Kucewicz, Michal T; Cimbalnik, Jan; Matsumoto, Joseph Y; Brinkmann, Benjamin H; Bower, Mark R; Vasoli, Vincent; Sulc, Vlastimil; Meyer, Fred; Marsh, W R; Stead, S M; Worrell, Gregory A

    2014-08-01

    High frequency oscillations are associated with normal brain function, but also increasingly recognized as potential biomarkers of the epileptogenic brain. Their role in human cognition has been predominantly studied in classical gamma frequencies (30-100 Hz), which reflect neuronal network coordination involved in attention, learning and memory. Invasive brain recordings in animals and humans demonstrate that physiological oscillations extend beyond the gamma frequency range, but their function in human cognitive processing has not been fully elucidated. Here we investigate high frequency oscillations spanning the high gamma (50-125 Hz), ripple (125-250 Hz) and fast ripple (250-500 Hz) frequency bands using intracranial recordings from 12 patients (five males and seven females, age 21-63 years) during memory encoding and recall of a series of affectively charged images. Presentation of the images induced high frequency oscillations in all three studied bands within the primary visual, limbic and higher order cortical regions in a sequence consistent with the visual processing stream. These induced oscillations were detected on individual electrodes localized in the amygdala, hippocampus and specific neocortical areas, revealing discrete oscillations of characteristic frequency, duration and latency from image presentation. Memory encoding and recall significantly modulated the number of induced high gamma, ripple and fast ripple detections in the studied structures, which was greater in the primary sensory areas during the encoding (Wilcoxon rank sum test, P = 0.002) and in the higher-order cortical association areas during the recall (Wilcoxon rank sum test, P = 0.001) of memorized images. Furthermore, the induced high gamma, ripple and fast ripple responses discriminated the encoded and the affectively charged images. In summary, our results show that high frequency oscillations, spanning a wide range of frequencies, are associated with memory processing and generated along distributed cortical and limbic brain regions. These findings support an important role for fast network synchronization in human cognition and extend our understanding of normal physiological brain activity during memory processing. © The Author (2014). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. Observation of contrast agent response to chirp insonation with a simultaneous optical-acoustical system.

    PubMed

    Sun, Yang; Zhao, Shukui; Dayton, Paul A; Ferrara, Katherine W

    2006-06-01

    Rayleigh-Plesset analysis, ultra-high speed photography, and single bubble acoustical recordings previously were applied independently to characterize the radial oscillation and resulting echoes from a microbubble in response to an ultrasonic pulse. In addition, high-speed photography has shown that microbubbles are destroyed over a single pulse or pulse train by diffusion and fragmentation. In order to develop a single model to characterize microbubble echoes based on oscillatory and destructive characteristics, an optical-acoustical system was developed to simultaneously record the optical image and backscattered echo from each microbubble. Combined observation provides the opportunity to compare predictions for oscillation and echoes with experimental results and identify discrepancies due to diffusion or fragmentation. Optimization of agents and insonating pulse parameters may be facilitated with this system. The mean correlation of the predicted and experimental radius-time curves and echoes exceeds 0.7 for the parameters studied here. An important application of this new system is to record and analyze microbubble response to a long pulse in which diffusion is shown to occur over the pulse duration. The microbubble response to an increasing or decreasing chirp is evaluated using this new tool. For chirp insonation beginning with the lower center frequency, low-frequency modulation of the oscillation envelope was obvious. However, low-frequency modulation was not observed in the radial oscillation produced by decreasing chirp insonation. Comparison of the echoes from similar sized microbubbles following increasing and decreasing chirp insonation demonstrated that the echoes were not time-reversed replicas. Using a transmission pressure of 620 kPa, the -6 dB echo length was 0.9 and 1.1 micros for increasing and decreasing chirp insonation, respectively (P = 0.02). The mean power in the low-frequency portion of the echoes was 8 (mV)2 and 13 (mV)2 for increasing and decreasing chirp insonation, respectively (P = 0.01).

  17. Observation of contrast agent response to chirp insonation with a simultaneous optical-acoustical system

    PubMed Central

    Sun, Yang; Zhao, Shukui; Dayton, Paul A.; Ferrara, Katherine W.

    2006-01-01

    Rayleigh-Plesset analysis, ultra-high speed photography, and single bubble acoustical recordings have previously been applied independently to characterize the radial oscillation and resulting echoes from a microbubble in response to an ultrasonic pulse. In addition, high speed photography has shown that microbubbles are destroyed over a single pulse or pulse train by diffusion and fragmentation. In order to develop a single model to characterize microbubble echoes based on oscillatory and destructive characteristics, an optical-acoustical system was developed to simultaneously record the optical image and backscattered echo from each microbubble. Combined observation provides the opportunity to compare predictions for oscillation and echoes with experimental results and identify discrepancies due to diffusion or fragmentation. Optimization of agents and insonating pulse parameters may be facilitated with this system. The mean correlation of the predicted and experimental radius-time curves and echoes exceeds 0.7 for the parameters studied here. An important application of this new system is to record and analyze microbubble response to a long pulse where diffusion is shown to occur over the pulse duration. The microbubble response to an increasing or decreasing chirp is evaluated using this new tool. For chirp insonation beginning with the lower center frequency, low frequency modulation of the oscillation envelope was obvious. However, low frequency modulation was not observed in the radial oscillation produced by decreasing chirp insonation. Comparison of the echoes from similar sized microbubbles following increasing and decreasing chirp insonation demonstrated that the echoes were not time-reversed replicas. Using a transmission pressure of 620 kPa, the −6 dB echo length was 0.9 and 1.1 μs for increasing and decreasing chirp insonation, respectively (P = 0.02). The mean power in the low frequency portion of the echoes was 8 (mV)2 and 13 (mV)2 for increasing and decreasing chirp insonation, respectively, (P = 0.01). PMID:16846145

  18. Local inertial oscillations in the surface ocean generated by time-varying winds

    NASA Astrophysics Data System (ADS)

    Chen, Shengli; Polton, Jeff A.; Hu, Jianyu; Xing, Jiuxing

    2015-12-01

    A new relationship is presented to give a review study on the evolution of inertial oscillations in the surface ocean locally generated by time-varying wind stress. The inertial oscillation is expressed as the superposition of a previous oscillation and a newly generated oscillation, which depends upon the time-varying wind stress. This relationship is employed to investigate some idealized wind change events. For a wind series varying temporally with different rates, the induced inertial oscillation is dominated by the wind with the greatest variation. The resonant wind, which rotates anti-cyclonically at the local inertial frequency with time, produces maximal amplitude of inertial oscillations, which grows monotonically. For the wind rotating at non-inertial frequencies, the responses vary periodically, with wind injecting inertial energy when it is in phase with the currents, but removing inertial energy when it is out of phase. The wind rotating anti-cyclonically with time is much more favorable to generate inertial oscillations than the cyclonic rotating wind. The wind with a frequency closer to the inertial frequency generates stronger inertial oscillations. For a diurnal wind, the induced inertial oscillation is dependent on latitude and is most significant at 30 °. This relationship is also applied to examine idealized moving cyclones. The inertial oscillation is much stronger on the right-hand side of the cyclone path than on the left-hand side (in the northern hemisphere). This is due to the wind being anti-cyclonic with time on the right-hand side, but cyclonic on the other side. The inertial oscillation varies with the cyclone translation speed. The optimal translation speed generating the greatest inertial oscillations is 2 m/s at the latitude of 10 ° and gradually increases to 6 m/s at the latitude of 30 °.

  19. Effect of motion artifacts and their correction on near-infrared spectroscopy oscillation data: a study in healthy subjects and stroke patients.

    PubMed

    Selb, Juliette; Yücel, Meryem A; Phillip, Dorte; Schytz, Henrik W; Iversen, Helle K; Vangel, Mark; Ashina, Messoud; Boas, David A

    2015-05-01

    Functional near-infrared spectroscopy is prone to contamination by motion artifacts (MAs). Motion correction algorithms have previously been proposed and their respective performance compared for evoked rain activation studies. We study instead the effect of MAs on "oscillation" data which is at the basis of functional connectivity and autoregulation studies. We use as our metric of interest the interhemispheric correlation (IHC), the correlation coefficient between symmetrical time series of oxyhemoglobin oscillations. We show that increased motion content results in a decreased IHC. Using a set of motion-free data on which we add real MAs, we find that the best motion correction approach consists of discarding the segments of MAs following a careful approach to minimize the contamination due to band-pass filtering of data from "bad" segments spreading into adjacent "good" segments. Finally, we compare the IHC in a stroke group and in a healthy group that we artificially contaminated with the MA content of the stroke group, in order to avoid the confounding effect of increased motion incidence in the stroke patients. After motion correction, the IHC remains lower in the stroke group in the frequency band around 0.1 and 0.04 Hz, suggesting a physiological origin for the difference. We emphasize the importance of considering MAs as a confounding factor in oscillation-based functional near-infrared spectroscopy studies.

  20. Submacropulse electron-beam dynamics correlated with higher-order modes in Tesla-type superconducting rf cavities

    NASA Astrophysics Data System (ADS)

    Lumpkin, A. H.; Thurman-Keup, R.; Edstrom, D.; Ruan, J.; Eddy, N.; Prieto, P.; Napoly, O.; Carlsten, B. E.; Bishofberger, K.

    2018-06-01

    We report the direct observations of submacropulse beam centroid oscillations correlated with higher order modes (HOMs) which were generated by off-axis electron beam steering in TESLA-type superconducting rf cavities. The experiments were performed at the Fermilab Accelerator Science and Technology (FAST) facility using its unique configuration of a photocathode rf gun injecting beam into two separated nine-cell cavities in series with corrector magnets and beam position monitors (BPMs) located before, between, and after them. Oscillations of ˜100 kHz in the vertical plane and ˜380 kHz in the horizontal plane with up to 600 -μ m amplitudes were observed in a 3-MHz micropulse repetition rate beam with charges of 100, 300, 500, and 1000 pC /b . However, the effects were much reduced at 100 pC /b . The measurements were based on HOM detector circuitry targeting the first and second dipole passbands, rf BPM bunch-by-bunch array data, imaging cameras, and a framing camera. Calculations reproduced the oscillation frequencies of the phenomena in the vertical case. In principle, these fundamental results may be scaled to cryomodule configurations of major accelerator facilities.

  1. Submacropulse electron-beam dynamics correlated with higher-order modes in Tesla-type superconducting rf cavities

    DOE PAGES

    Lumpkin, A. H.; Thurman-Keup, R.; Edstrom, D.; ...

    2018-06-04

    Here, we report the direct observations of submacropulse beam centroid oscillations correlated with higher order modes (HOMs) which were generated by off-axis electron beam steering in TESLA-type superconducting rf cavities. The experiments were performed at the Fermilab Accelerator Science and Technology (FAST) facility using its unique configuration of a photocathode rf gun injecting beam into two separated nine-cell cavities in series with corrector magnets and beam position monitors (BPMs) located before, between, and after them. Oscillations of ~100 kHz in the vertical plane and ~380 kHz in the horizontal plane with up to 600-μm amplitudes were observed in a 3-MHzmore » micropulse repetition rate beam with charges of 100, 300, 500, and 1000 pC/b. However, the effects were much reduced at 100 pC/b. The measurements were based on HOM detector circuitry targeting the first and second dipole passbands, rf BPM bunch-by-bunch array data, imaging cameras, and a framing camera. Calculations reproduced the oscillation frequencies of the phenomena in the vertical case. In principle, these fundamental results may be scaled to cryomodule configurations of major accelerator facilities.« less

  2. [Coupling of brain oscillatory systems with cognitive (experience and valence) and physiological (cardiovascular reactivity) components of emotion].

    PubMed

    Aftanas, L I; Reva, N V; Pavlov, S V; Korenek, V V; Brak, I V

    2014-02-01

    We investigated the coupling of EEG oscillators with cognitive (experience and valence) and physiological (cardiovascular reactivity) components of emotion. Emotions of anger and joy were evoked in healthy males (n = 49) using a guided imagery method, multichannel EEG and cardiovascular reactivity (Finometer) were simultaneously recorded. Correlational analysis revealed that specially distributed EEG oscillators seem to be selectively involved into cognitive (experience and valence) and physiological (cardiovascular reactivity) components of emotional responding. We showed that low theta (4-6 Hz) activity from medial and lateral frontal cortex of the right hemisphere predominantly correlated with the anger experience, high alpha (10-12 and 12-14 Hz) and gamma (30-45 Hz) activity from central-parieto-occipital regions of the left hemisphere--with cardiovascular reactivity to anger and joy, gamma-activity (30-45 Hz) from the left hemisphere in parietal areas--with cardiovascular reactivity to joy. The findings suggest that specially distributed neuronal networks oscillating at different frequencies may be regarded as a putative neurobiological mechanism coordination dynamical balance between cognitive and physiological components of emotion as well as psycho-neuro-somatic relationships within the mind-brain-body system.

  3. Rayleigh-enhanced attosecond sum-frequency polarization beats via twin color-locking noisy lights

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang Yanpeng; Li Long; Ma Ruiqiong

    2005-07-15

    Based on color-locking noisy field correlation, a time-delayed method is proposed to suppress the thermal effect, and the ultrafast longitudinal relaxation time can be measured even in an absorbing medium. One interesting feature in field-correlation effects is that Rayleigh-enhanced four-wave mixing (RFWM) with color-locking noisy light exhibits spectral symmetry and temporal asymmetry with no coherence spike at {tau}=0. Due to the interference between the Rayleigh-resonant signal and the nonresonant background, RFWM exhibits hybrid radiation-matter detuning with terahertz damping oscillations. The subtle Markovian high-order correlation effects have been investigated in the homodyne- or heterodyne-detected Rayleigh-enhanced attosecond sum-frequency polarization beats (RASPBs). Analyticmore » closed forms of fourth-order Markovian stochastic correlations are characterized for homodyne (quadratic) and heterodyne (linear) detection, respectively. Based on the polarization interference between two four-wave mixing processes, the phase-sensitive detection of RASPBs has also been used to obtain the real and imaginary parts of the Rayleigh resonance.« less

  4. Facilitation of epileptic activity during sleep is mediated by high amplitude slow waves

    PubMed Central

    von Ellenrieder, Nicolás; Ferrari-Marinho, Taissa; Avoli, Massimo; Dubeau, François; Gotman, Jean

    2015-01-01

    Epileptic discharges in focal epilepsy are frequently activated during non-rapid eye movement sleep. Sleep slow waves are present during this stage and have been shown to include a deactivated (‘down’, hyperpolarized) and an activated state (‘up’, depolarized). The ‘up’ state enhances physiological rhythms, and we hypothesize that sleep slow waves and particularly the ‘up’ state are the specific components of non-rapid eye movement sleep that mediate the activation of epileptic activity. We investigated eight patients with pharmaco-resistant focal epilepsies who underwent combined scalp-intracerebral electroencephalography for diagnostic evaluation. We analysed 259 frontal electroencephalographic channels, and manually marked 442 epileptic spikes and 8487 high frequency oscillations during high amplitude widespread slow waves, and during matched control segments with low amplitude widespread slow waves, non-widespread slow waves or no slow waves selected during the same sleep stages (total duration of slow wave and control segments: 49 min each). During the slow waves, spikes and high frequency oscillations were more frequent than during control segments (79% of spikes during slow waves and 65% of high frequency oscillations, both P ∼ 0). The spike and high frequency oscillation density also increased for higher amplitude slow waves. We compared the density of spikes and high frequency oscillations between the ‘up’ and ‘down’ states. Spike and high frequency oscillation density was highest during the transition from the ‘up’ to the ‘down’ state. Interestingly, high frequency oscillations in channels with normal activity expressed a different peak at the transition from the ‘down’ to the ‘up’ state. These results show that the apparent activation of epileptic discharges by non-rapid eye movement sleep is not a state-dependent phenomenon but is predominantly associated with specific events, the high amplitude widespread slow waves that are frequent, but not continuous, during this state of sleep. Both epileptic spikes and high frequency oscillations do not predominate, like physiological activity, during the ‘up’ state but during the transition from the ‘up’ to the ‘down’ state of the slow wave, a period of high synchronization. Epileptic discharges appear therefore more associated with synchronization than with excitability. Furthermore, high frequency oscillations in channels devoid of epileptic activity peak differently during the slow wave cycle from those in channels with epileptic activity. This property may allow differentiating physiological from pathological high frequency oscillations, a problem that is unresolved until now. PMID:25792528

  5. Magnetosphere-Ionosphere-Thermosphere Response to Quasi-periodic Oscillations in Solar Wind Driving Conditions

    NASA Astrophysics Data System (ADS)

    Liu, J.; Wang, W.; Zhang, B.; Huang, C.

    2017-12-01

    Periodical oscillations with periods of several tens of minutes to several hours are commonly seen in the Alfven wave embedded in the solar wind. It is yet to be known how the solar wind oscillation frequency modulates the solar wind-magnetosphere-ionosphere coupled system. Utilizing the Coupled Magnetosphere-Ionosphere-Thermosphere Model (CMIT), we analyzed the magnetosphere-ionosphere-thermosphere system response to IMF Bz oscillation with periods of 10, 30, and 60 minutes from the perspective of energy budget and electrodynamic coupling processes. Our results indicate that solar wind energy coupling efficiency depends on IMF Bz oscillation frequency; energy coupling efficiency, represented by the ratio between globally integrated Joule heating and Epsilon function, is higher for lower frequency IMF Bz oscillation. Ionospheric Joule heating dissipation not only depends on the direct solar wind driven process but also is affected by the intrinsic nature of magnetosphere (i.e. loading-unloading process). In addition, ionosphere acts as a low-pass filter and tends to filter out very high-frequency solar wind oscillation (i.e. shorter than 10 minutes). Ionosphere vertical ion drift is most sensitive to IMF Bz oscillation compared to hmF2, and NmF2, while NmF2 is less sensitive. This can account for not synchronized NmF2 and hmF2 response to penetration electric fields in association with fast solar wind changes. This research highlights the critical role of IMF Bz oscillation frequency in constructing energy coupling function and understanding electrodynamic processes in the coupled solar wind-magnetosphere-ionosphere system.

  6. Dependence of the colored frequency noise in spin torque oscillators on current and magnetic field

    NASA Astrophysics Data System (ADS)

    Eklund, Anders; Bonetti, Stefano; Sani, Sohrab R.; Majid Mohseni, S.; Persson, Johan; Chung, Sunjae; Amir Hossein Banuazizi, S.; Iacocca, Ezio; Östling, Mikael; Åkerman, Johan; Gunnar Malm, B.

    2014-03-01

    The nano-scale spin torque oscillator (STO) is a compelling device for on-chip, highly tunable microwave frequency signal generation. Currently, one of the most important challenges for the STO is to increase its longer-time frequency stability by decreasing the 1/f frequency noise, but its high level makes even its measurement impossible using the phase noise mode of spectrum analyzers. Here, we present a custom made time-domain measurement system with 150 MHz measurement bandwidth making possible the investigation of the variation of the 1/f as well as the white frequency noise in a STO over a large set of operating points covering 18-25 GHz. The 1/f level is found to be highly dependent on the oscillation amplitude-frequency non-linearity and the vicinity of unexcited oscillation modes. These findings elucidate the need for a quantitative theoretical treatment of the low-frequency, colored frequency noise in STOs. Based on the results, we suggest that the 1/f frequency noise possibly can be decreased by improving the microstructural quality of the metallic thin films.

  7. The Amount of Time Dilation for Visual Flickers Corresponds to the Amount of Neural Entrainments Measured by EEG.

    PubMed

    Hashimoto, Yuki; Yotsumoto, Yuko

    2018-01-01

    The neural basis of time perception has long attracted the interests of researchers. Recently, a conceptual model consisting of neural oscillators was proposed and validated by behavioral experiments that measured the dilated duration in perception of a flickering stimulus (Hashimoto and Yotsumoto, 2015). The model proposed that flickering stimuli cause neural entrainment of oscillators, resulting in dilated time perception. In this study, we examined the oscillator-based model of time perception, by collecting electroencephalography (EEG) data during an interval-timing task. Initially, subjects observed a stimulus, either flickering at 10-Hz or constantly illuminated. The subjects then reproduced the duration of the stimulus by pressing a button. As reported in previous studies, the subjects reproduced 1.22 times longer durations for flickering stimuli than for continuously illuminated stimuli. The event-related potential (ERP) during the observation of a flicker oscillated at 10 Hz, reflecting the 10-Hz neural activity phase-locked to the flicker. Importantly, the longer reproduced duration was associated with a larger amplitude of the 10-Hz ERP component during the inter-stimulus interval, as well as during the presentation of the flicker. The correlation between the reproduced duration and the 10-Hz oscillation during the inter-stimulus interval suggested that the flicker-induced neural entrainment affected time dilation. While the 10-Hz flickering stimuli induced phase-locked entrainments at 10 Hz, we also observed event-related desynchronizations of spontaneous neural oscillations in the alpha-frequency range. These could be attributed to the activation of excitatory neurons while observing the flicker stimuli. In addition, neural activity at approximately the alpha frequency increased during the reproduction phase, indicating that flicker-induced neural entrainment persisted even after the offset of the flicker. In summary, our results suggest that the duration perception is mediated by neural oscillations, and that time dilation induced by flickering visual stimuli can be attributed to neural entrainment.

  8. Position control system for use with micromechanical actuators

    DOEpatents

    Guckel, Henry; Stiers, Eric W.

    2000-01-01

    A positioning system adapted for use with micromechanical actuators provides feedback control of the position of the movable element of the actuator utilizing a low Q sensing coil. The effective inductance of the sensing coil changes with position of the movable element to change the frequency of oscillation of a variable oscillator. The output of the variable oscillator is compared in a phase detector to a reference oscillator signal. The phase detector provides a pulsed output having a pulse duty cycle related to the phase or frequency difference between the oscillator signals. The output of the phase detector is provided to a drive coil which applies a magnetic force to the movable element which balances the force of a spring. The movable element can be displaced to a new position by changing the frequency of the reference oscillator.

  9. On a relativistic particle and a relativistic position-dependent mass particle subject to the Klein–Gordon oscillator and the Coulomb potential

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vitória, R.L.L.; Furtado, C., E-mail: furtado@fisica.ufpb.br; Bakke, K., E-mail: kbakke@fisica.ufpb.br

    2016-07-15

    The relativistic quantum dynamics of an electrically charged particle subject to the Klein–Gordon oscillator and the Coulomb potential is investigated. By searching for relativistic bound states, a particular quantum effect can be observed: a dependence of the angular frequency of the Klein–Gordon oscillator on the quantum numbers of the system. The meaning of this behaviour of the angular frequency is that only some specific values of the angular frequency of the Klein–Gordon oscillator are permitted in order to obtain bound state solutions. As an example, we obtain both the angular frequency and the energy level associated with the ground statemore » of the relativistic system. Further, we analyse the behaviour of a relativistic position-dependent mass particle subject to the Klein–Gordon oscillator and the Coulomb potential.« less

  10. Stochastic Multiresonance for a Fractional Linear Oscillator with Quadratic Trichotomous Noise

    NASA Astrophysics Data System (ADS)

    Zhu, Jian-Qu; Jin, Wei-Dong; Zheng, Gao; Guo, Feng

    2017-11-01

    The stochastic multiresonance behavior for a fractional linear oscillator with random system frequency is investigated. The fluctuation of the system frequency is a quadratic trichotomous noise, the memory kernel of the fractional oscillator is modeled as a Mittag-Leffler function. Based on linear system theory, applying Laplace transform and the definition of fractional derivative, the expression of the system output amplitude (SPA) is obtained. Stochastic multiresonance phenomenon is found on the curves of SPA versus the memory time and the memory exponent of the fractional oscillator, as well as versus the trichotomous noise amplitude. The SPA depends non-monotonically on the stationary probability of the trichotomous noise, on the viscous damping coefficient and system characteristic frequency of the oscillator, as well as on the driving frequency of external force. Supported by National Natural Science Foundation of China under Grant No. 61134002

  11. Frequency transitions in odor-evoked neural oscillations

    PubMed Central

    Ito, Iori; Bazhenov, Maxim; Ong, Rose Chik-ying; Raman, Baranidharan; Stopfer, Mark

    2009-01-01

    Summary In many species sensory stimuli elicit the oscillatory synchronization of groups of neurons. What determines the properties of these oscillations? In the olfactory system of the moth we found that odors elicited oscillatory synchronization through a neural mechanism like that described in locust and Drosophila. During responses to long odor pulses, oscillations suddenly slowed as net olfactory receptor neuron (ORN) output decreased; thus, stimulus intensity appeared to determine oscillation frequency. However, changing the concentration of the odor had little effect upon oscillatory frequency. Our recordings in vivo and computational models based on these results suggested the main effect of increasing odor concentration was to recruit additional, less well-tuned ORNs whose firing rates were tightly constrained by adaptation and saturation. Thus, in the periphery, concentration is encoded mainly by the size of the responsive ORN population, and oscillation frequency is set by the adaptation and saturation of this response. PMID:20005825

  12. Frequency transitions in odor-evoked neural oscillations.

    PubMed

    Ito, Iori; Bazhenov, Maxim; Ong, Rose Chik-ying; Raman, Baranidharan; Stopfer, Mark

    2009-12-10

    In many species, sensory stimuli elicit the oscillatory synchronization of groups of neurons. What determines the properties of these oscillations? In the olfactory system of the moth, we found that odors elicited oscillatory synchronization through a neural mechanism like that described in locust and Drosophila. During responses to long odor pulses, oscillations suddenly slowed as net olfactory receptor neuron (ORN) output decreased; thus, stimulus intensity appeared to determine oscillation frequency. However, changing the concentration of the odor had little effect upon oscillatory frequency. Our recordings in vivo and computational models based on these results suggested that the main effect of increasing odor concentration was to recruit additional, less well-tuned ORNs whose firing rates were tightly constrained by adaptation and saturation. Thus, in the periphery, concentration is encoded mainly by the size of the responsive ORN population, and oscillation frequency is set by the adaptation and saturation of this response.

  13. Burst Oscillation Probes of Neutron Stars and Nuclear Burning with LOFT

    NASA Technical Reports Server (NTRS)

    Strohmayer, Tod

    2012-01-01

    X-ray brightness oscillations during thermonuclear X-ray bursts--burst oscillations--have provided a new probe of neutron star spins as well as of the dependent nuclear burning processes. The frequency drift and amplitude evolution of the oscillations observed during bursts can in principle place constraints on the physics of thermonuclear flame spreading and the dynamics of the burning atmosphere. I use simulations appropriate to LOFT to explore the precision with which the time dependence of the oscillation frequency can be inferred. This can test, for example, different models for the frequency drift, such as up-lift versus geostrophic drift. I also explore the precision with which asymptotic frequencies can be constrained in order to estimate the capability for LOFT to detect the Doppler shifts induced by orbital motion of the neutron star from a sample of bursts at different orbital phases.

  14. Phase-locking dynamics in optoelectronic oscillator

    NASA Astrophysics Data System (ADS)

    Banerjee, Abhijit; Sarkar, Jayjeet; Das, NikhilRanjan; Biswas, Baidyanath

    2018-05-01

    This paper analyzes the phase-locking phenomenon in single-loop optoelectronic microwave oscillators considering weak and strong radio frequency (RF) signal injection. The analyses are made in terms of the lock-range, beat frequency and the spectral components of the unlocked-driven oscillator. The influence of RF injection signal on the frequency pulling of the unlocked-driven optoelectronic oscillator (OEO) is also studied. An approximate expression for the amplitude perturbation of the oscillator is derived and the influence of amplitude perturbation on the phase-locking dynamics is studied. It is shown that the analysis clearly reveals the phase-locking phenomenon and the associated frequency pulling mechanism starting from the fast-beat state through the quasi-locked state to the locked state of the pulled OEO. It is found that the unlocked-driven OEO output signal has a very non-symmetrical sideband distribution about the carrier. The simulation results are also given in partial support to the conclusions of the analysis.

  15. High-frequency modulation of ion-acoustic waves.

    NASA Technical Reports Server (NTRS)

    Albright, N. W.

    1972-01-01

    A large amplitude, high-frequency electromagnetic oscillation is impressed on a nonrelativistic, collisionless plasma from an external source. The frequency is chosen to be far from the plasma frequency (in fact, lower). The resulting electron velocity distribution function strongly modifies the propagation of ion-acoustic waves parallel to the oscillating electric field. The complex frequency is calculated numerically.

  16. A frequency tunable, eight-channel correlation ECE system for electron temperature turbulence measurements on the DIII-D tokamak

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sung, C., E-mail: csung@physics.ucla.edu; Peebles, W. A.; Wannberg, C.

    2016-11-15

    A new eight-channel correlation electron cyclotron emission diagnostic has recently been installed on the DIII-D tokamak to study both turbulent and coherent electron temperature fluctuations under various plasma conditions and locations. This unique system is designed to cover a broad range of operation space on DIII-D (1.6-2.1 T, detection frequency: 72-108 GHz) via four remotely selected local oscillators (80, 88, 96, and 104 GHz). Eight radial locations are measured simultaneously in a single discharge covering as much as half the minor radius. In this paper, we present design details of the quasi-optical system, the receiver, as well as representative datamore » illustrating operation of the system.« less

  17. Atomic Force Microscopy | Materials Science | NREL

    Science.gov Websites

    , the cantilever is oscillated close to its resonant frequency, while the amplitude of the oscillation resonant frequency, which in turns changes the oscillation amplitude. The change in the amplitude is the of photodiodes. Because it uses the force as interaction, AFM can generate high magnifications (up to

  18. Field Potential Oscillations in the Bed Nucleus of the Stria Terminalis Correlate with Compulsion in a Rat Model of Obsessive-Compulsive Disorder.

    PubMed

    Wu, Hemmings; Tambuyzer, Tim; Nica, Ioana; Deprez, Marjolijn; van Kuyck, Kris; Aerts, Jean-Marie; Van Huffel, Sabine; Nuttin, Bart

    2016-09-28

    The bed nucleus of the stria terminalis (BNST) is implicated in anxiety and reward processing, both of which are associated with obsessive-compulsive disorder (OCD). Specific neuronal groups in the BNST related to anxiety and reward have been identified, but quantitative data about the information carried by local field potential (LFP) signals in this area during obsession/compulsion are lacking. Here we investigate the BNST LFP in the schedule-induced polydipsia, an animal model of OCD. We implanted electrodes bilaterally in the BNST and random control brain regions in 32 male Wistar rats, and recorded corresponding LFP during compulsive and noncompulsive behavior. We first applied high-frequency (100 Hz) electrical stimulation through the implanted electrodes and analyzed its effects on compulsive behavior. We then performed time-frequency analysis of LFPs and statistically compared the normalized power of δ (1-4 Hz), θ (4-8 Hz), α (8-12 Hz), β (12-30 Hz), and lower γ (30-45 Hz) bands between different groups. Our data showed that the normalized δ, β, and γ powers in the right BNST were specifically correlated with compulsive behaviors. δ and γ oscillations increased and decreased during the initiation phase of compulsion, respectively, whereas β increased after compulsion stopped. Moreover, the effect of BNST electrical stimulation, in terms of suppression of compulsion, was significantly correlated with the percentage change of these bands during compulsion. Our research reveals potential biomarkers and underlying neurophysiological mechanisms of compulsion and warrants further assessment of the use of LFP for closed-loop neuromodulation in OCD. Although specific neuronal groups in the bed nucleus of the stria terminalis (BNST) related to anxiety and reward circuitries have been identified, psychopathological information carried by local field potentials in the BNST has not yet been described. We discovered that normalized powers of the right BNST δ, β, and γ oscillations were highly correlated with compulsion. Specifically, δ and γ oscillations increased and decreased during the initiation phase of compulsion, respectively, whereas β increased after compulsion stopped. Such correlations were not found in other parts of the brain during compulsion, or in the BNST during noncompulsive behavior. Current findings reveal real-time neurophysiological biomarkers of compulsion and warrant further assessment of the use of local field potentials for closed-loop neuromodulation for OCD. Copyright © 2016 the authors 0270-6474/16/3610051-10$15.00/0.

  19. Multi-Frequency Recirculating Planar Magnetrons

    NASA Astrophysics Data System (ADS)

    Greening, Geoffrey Bruce

    The cavity magnetron is generally accepted as the standard for compactness and high microwave power with applications in industry, science, and defense, with the latter including counter-electronics. In this application, magnetrons are limited because they are narrowband devices. To expand the range of frequencies that can be produced using a single magnetron, a novel multi-frequency variant of the Recirculating Planar Magnetron (RPM) was designed, fabricated, and experimentally demonstrated. This multi-frequency RPM (MFRPM) was the first high-power magnetron capable of generating multiple microwave frequencies simultaneously and demonstrated the first known instance of harmonic frequency-locking in a magnetron. The MFRPM design consisted of two planar cavity arrays coupled by cylindrical electron recirculation bends. The two arrays formed a 1 GHz L-Band Oscillator (LBO) and a 2 GHz S-Band Oscillator (SBO). Experiments were conducted using a 0.1-0.3 T axial magnetic field produced using a pulsed pair of Helmholtz coils and a -300 kV, 200-400 ns, 1-5 kA pulse applied to a Mode-Control Cathode (MCC) using the MELBA-C Marx generator. Six experimental configurations were tested using three anodes (the isolated LBO, the isolated SBO, and the MFRPM), two microwave loads (a standard, matched load, and a waveguide taper load used to characterize the LBO frequency harmonics), and two axial magnetic fields (uniform and nonuniform). Using these configurations, an in-depth characterization of MFRPM operation determined 1) the identity of the observed electromagnetic modes, and the degree of mode competition, 2) the frequencies, powers, and other electrical characteristics associated with those modes and the LBO frequency harmonics, 3) the magnetic fields corresponding to optimal operation, 4) the operational impact of a nonuniform axial magnetic field, and 5) the origin and performance characteristics of a novel harmonic frequency-locked state observed in the MFRPM. The uniform magnetic field consistently yielded better performance relative to the nonuniform magnetic field. In the harmonic frequency-locked state at 0.17 T with the uniform magnetic field, the MFRPM LBO produced 32 +/- 3 MW at 0.984 +/- 0.001 GHz, and the SBO produced 13 +/- 2 MW at 1.970 +/- 0.002 GHz. Relative to the other operating states, the locked state was remarkably consistent. In B = 0.16-0.17 T, the phase drift during a typical locked shot was 8 +/- 4°, and the lock duration was 14 +/- 3 ns. The average phase difference between the oscillators was 93+/-17°. The locking appeared to be Adler-like, where the LBO was the driving oscillator and the SBO was the driven oscillator. Changes in the relative phase difference between the oscillators correlated with changes in the magnetic field, suggesting the coupling occurred through the second harmonic content of the LBO-modulated electron beam as it propagated from the LBO to the SBO. A comparison of the experimental results for this locked state with a new theory for harmonic locking was inconclusive. Using the uniform magnetic field at 0.17 T, the LBO second harmonic power was 178 +/- 60 kW at 1.962 +/- 0.013 GHz. The LBO fourth harmonic power was 5 +/- 1 kW at 3.916 +/- 0.018 GHz. In general, LBO harmonic powers increased when the fundamental circuit modes were operating at reduced power with considerable mode competition. Harmonic powers were also as much as 150% higher using the nonuniform magnetic field relative to the uniform magnetic field.

  20. Effect of stimulus intensity on spike-LFP relationship in Secondary Somatosensory cortex

    PubMed Central

    Hsiao, Steven S.; Crone, Nathan E.; Franaszczuk, Piotr J.; Niebur, Ernst

    2008-01-01

    Neuronal oscillations in the gamma frequency range have been reported in many cortical areas, but the role they play in cortical processing remains unclear. We tested a recently proposed hypothesis that the intensity of sensory input is coded in the timing of action potentials relative to the phase of gamma oscillations, thus converting amplitude information to a temporal code. We recorded spikes and local field potential (LFP) from secondary somatosensory (SII) cortex in awake monkeys while presenting a vibratory stimulus at different amplitudes. We developed a novel technique based on matching pursuit to study the interaction between the highly transient gamma oscillations and spikes with high time-frequency resolution. We found that spikes were weakly coupled to LFP oscillations in the gamma frequency range (40−80 Hz), and strongly coupled to oscillations in higher gamma frequencies. However, the phase relationship of neither low-gamma nor high-gamma oscillations changed with stimulus intensity, even with a ten-fold increase. We conclude that, in SII, gamma oscillations are synchronized with spikes, but their phase does not vary with stimulus intensity. Furthermore, high-gamma oscillations (>60 Hz) appear to be closely linked to the occurrence of action potentials, suggesting that LFP high-gamma power could be a sensitive index of the population firing rate near the microelectrode. PMID:18632937

  1. Measurements of temperature characteristics and estimation of terahertz negative differential conductance in resonant-tunneling-diode oscillators

    NASA Astrophysics Data System (ADS)

    Asada, M.; Suzuki, S.; Fukuma, T.

    2017-11-01

    The temperature dependences of output power, oscillation frequency, and current-voltage curve are measured for resonant-tunneling-diode terahertz (THz) oscillators. The output power largely changes with temperature owing to the change in Ohmic loss. In contrast to the output power, the oscillation frequency and current-voltage curve are almost insensitive to temperature. The measured temperature dependence of output power is compared with the theoretical calculation including the negative differential conductance (NDC) as a fitting parameter assumed to be independent of temperature. Very good agreement was obtained between the measurement and calculation, and the NDC in the THz frequency region is estimated. The results show that the absolute values of NDC in the THz region significantly decrease relative to that at DC, and increases with increasing frequency in the measured frequency range.

  2. Perturbation of myo-inositol-1,4,5-trisphosphate levels during agonist-induced Ca2+ oscillations.

    PubMed Central

    Chatton, J Y; Cao, Y; Stucki, J W

    1998-01-01

    Agonist-induced Ca2+ oscillations in rat hepatocytes involve the production of myo-inositol-1,4,5-trisphosphate (IP3), which stimulates the release of Ca2+ from intracellular stores. The oscillatory frequency is conditioned by the agonist concentration. This study investigated the role of IP3 concentration in the modulation of oscillatory frequency by using microinjected photolabile IP3 analogs. Photorelease of IP3 during hormone-induced oscillations evoked a Ca2+ spike, after which oscillations resumed with a delay corresponding to the period set by the agonists. IP3 photorelease had no influence on the frequency of oscillations. After photorelease of 1-(alpha-glycerophosphoryl)-D-myo-inositol-4,5-diphosphate (GPIP2), a slowly metabolized IP3 analog, the frequency of oscillations initially increased by 34% and declined to its original level within approximately 6 min. Both IP3 and GPIP2 effects can be explained by their rate of degradation: the half-life of IP3, which is a few seconds, can account for the lack of influence of IP3 photorelease on the frequency, whereas the slower metabolism of GPIP2 allowed a transient acceleration of the oscillations. The phase shift introduced by IP3 is likely the result of the brief elevation of Ca2+ during spiking that resets the IP3 receptor to a state of maximum inactivation. A mathematical model of Ca2+ oscillations is in satisfactory agreement with the observed results. PMID:9449352

  3. Respiratory modulation of human autonomic rhythms

    NASA Technical Reports Server (NTRS)

    Badra, L. J.; Cooke, W. H.; Hoag, J. B.; Crossman, A. A.; Kuusela, T. A.; Tahvanainen, K. U.; Eckberg, D. L.

    2001-01-01

    We studied the influence of three types of breathing [spontaneous, frequency controlled (0.25 Hz), and hyperventilation with 100% oxygen] and apnea on R-R interval, photoplethysmographic arterial pressure, and muscle sympathetic rhythms in nine healthy young adults. We integrated fast Fourier transform power spectra over low (0.05-0.15 Hz) and respiratory (0.15-0.3 Hz) frequencies; estimated vagal baroreceptor-cardiac reflex gain at low frequencies with cross-spectral techniques; and used partial coherence analysis to remove the influence of breathing from the R-R interval, systolic pressure, and muscle sympathetic nerve spectra. Coherence among signals varied as functions of both frequency and time. Partialization abolished the coherence among these signals at respiratory but not at low frequencies. The mode of breathing did not influence low-frequency oscillations, and they persisted during apnea. Our study documents the independence of low-frequency rhythms from respiratory activity and suggests that the close correlations that may exist among arterial pressures, R-R intervals, and muscle sympathetic nerve activity at respiratory frequencies result from the influence of respiration on these measures rather than from arterial baroreflex physiology. Most importantly, our results indicate that correlations among autonomic and hemodynamic rhythms vary over time and frequency, and, thus, are facultative rather than fixed.

  4. One node driving synchronisation

    NASA Astrophysics Data System (ADS)

    Wang, Chengwei; Grebogi, Celso; Baptista, Murilo S.

    2015-12-01

    Abrupt changes of behaviour in complex networks can be triggered by a single node. This work describes the dynamical fundamentals of how the behaviour of one node affects the whole network formed by coupled phase-oscillators with heterogeneous coupling strengths. The synchronisation of phase-oscillators is independent of the distribution of the natural frequencies, weakly depends on the network size, but highly depends on only one key oscillator whose ratio between its natural frequency in a rotating frame and its coupling strength is maximum. This result is based on a novel method to calculate the critical coupling strength with which the phase-oscillators emerge into frequency synchronisation. In addition, we put forward an analytical method to approximately calculate the phase-angles for the synchronous oscillators.

  5. One node driving synchronisation

    PubMed Central

    Wang, Chengwei; Grebogi, Celso; Baptista, Murilo S.

    2015-01-01

    Abrupt changes of behaviour in complex networks can be triggered by a single node. This work describes the dynamical fundamentals of how the behaviour of one node affects the whole network formed by coupled phase-oscillators with heterogeneous coupling strengths. The synchronisation of phase-oscillators is independent of the distribution of the natural frequencies, weakly depends on the network size, but highly depends on only one key oscillator whose ratio between its natural frequency in a rotating frame and its coupling strength is maximum. This result is based on a novel method to calculate the critical coupling strength with which the phase-oscillators emerge into frequency synchronisation. In addition, we put forward an analytical method to approximately calculate the phase-angles for the synchronous oscillators. PMID:26656718

  6. Elastomer degradation sensor using a piezoelectric material

    DOEpatents

    Olness, Dolores U.; Hirschfeld, deceased, Tomas B.

    1990-01-01

    A method and apparatus for monitoring the degradation of elastomeric materials is provided. Piezoelectric oscillators are placed in contact with the elastomeric material so that a forced harmonic oscillator with damping is formed. The piezoelectric material is connected to an oscillator circuit,. A parameter such as the resonant frequency, amplitude or Q value of the oscillating system is related to the elasticity of the elastomeric material. Degradation of the elastomeric material causes changes in its elasticity which, in turn, causes the resonant frequency, amplitude or Q of the oscillator to change. These changes are monitored with a peak height monitor, frequency counter, Q-meter, spectrum analyzer, or other measurement circuit. Elasticity of elastomers can be monitored in situ, using miniaturized sensors.

  7. Synchronization of low-frequency oscillations in the cardiovascular system: Application to medical diagnostics and treatment

    NASA Astrophysics Data System (ADS)

    Ponomarenko, V. I.; Prokhorov, M. D.; Karavaev, A. S.; Kiselev, A. R.; Gridnev, V. I.; Bezruchko, B. P.

    2013-10-01

    We investigate synchronization between the low-frequency oscillations of heart rate and blood pressure having in humans a basic frequency close to 0.1 Hz. A quantitative estimation of this synchronization based on calculation of relative time of phase synchronization of oscillations is proposed. We show that assessment of synchronization between the considered oscillations can be useful for selecting an optimal dose of beta-blocker treatment in patients after acute myocardial infarction. It is found out that low value of synchronization between the low-frequency rhythms in heart rate and blood pressure at the first week after acute myocardial infarction is a sensitive marker of high risk of mortality during the subsequent 5 years.

  8. Microwave ice accretion meter

    NASA Technical Reports Server (NTRS)

    Magenheim, Bertram (Inventor); Rocks, James K. (Inventor)

    1984-01-01

    A system for indicating ice thickness and rate of ice thickness growth on surfaces is disclosed. The region to be monitored for ice accretion is provided with a resonant surface waveguide which is mounted flush, below the surface being monitored. A controlled oscillator provides microwave energy via a feed point at a controllable frequency. A detector is coupled to the surface waveguide and is responsive to electrical energy. A measuring device indicates the frequency deviation of the controlled oscillator from a quiescent frequency. A control means is provided to control the frequency of oscillation of the controlled oscillator. In a first, open-loop embodiment, the control means is a shaft operated by an operator. In a second, closed-loop embodiment, the control means is a processor which effects automatic control.

  9. Scale-Free Neural and Physiological Dynamics in Naturalistic Stimuli Processing

    PubMed Central

    Lin, Amy

    2016-01-01

    Abstract Neural activity recorded at multiple spatiotemporal scales is dominated by arrhythmic fluctuations without a characteristic temporal periodicity. Such activity often exhibits a 1/f-type power spectrum, in which power falls off with increasing frequency following a power-law function: P(f)∝1/fβ, which is indicative of scale-free dynamics. Two extensively studied forms of scale-free neural dynamics in the human brain are slow cortical potentials (SCPs)—the low-frequency (<5 Hz) component of brain field potentials—and the amplitude fluctuations of α oscillations, both of which have been shown to carry important functional roles. In addition, scale-free dynamics characterize normal human physiology such as heartbeat dynamics. However, the exact relationships among these scale-free neural and physiological dynamics remain unclear. We recorded simultaneous magnetoencephalography and electrocardiography in healthy subjects in the resting state and while performing a discrimination task on scale-free dynamical auditory stimuli that followed different scale-free statistics. We observed that long-range temporal correlation (captured by the power-law exponent β) in SCPs positively correlated with that of heartbeat dynamics across time within an individual and negatively correlated with that of α-amplitude fluctuations across individuals. In addition, across individuals, long-range temporal correlation of both SCP and α-oscillation amplitude predicted subjects’ discrimination performance in the auditory task, albeit through antagonistic relationships. These findings reveal interrelations among different scale-free neural and physiological dynamics and initial evidence for the involvement of scale-free neural dynamics in the processing of natural stimuli, which often exhibit scale-free dynamics. PMID:27822495

  10. Resonance frequencies of lipid-shelled microbubbles in the regime of nonlinear oscillations

    PubMed Central

    Doinikov, Alexander A.; Haac, Jillian F.; Dayton, Paul A.

    2009-01-01

    Knowledge of resonant frequencies of contrast microbubbles is important for the optimization of ultrasound contrast imaging and therapeutic techniques. To date, however, there are estimates of resonance frequencies of contrast microbubbles only for the regime of linear oscillation. The present paper proposes an approach for evaluating resonance frequencies of contrast agent microbubbles in the regime of nonlinear oscillation. The approach is based on the calculation of the time-averaged oscillation power of the radial bubble oscillation. The proposed procedure was verified for free bubbles in the frequency range 1–4 MHz and then applied to lipid-shelled microbubbles insonified with a single 20-cycle acoustic pulse at two values of the acoustic pressure amplitude, 100 kPa and 200 kPa, and at four frequencies: 1.5, 2.0, 2.5, and 3.0 MHz. It is shown that, as the acoustic pressure amplitude is increased, the resonance frequency of a lipid-shelled microbubble tends to decrease in comparison with its linear resonance frequency. Analysis of existing shell models reveals that models that treat the lipid shell as a linear viscoelastic solid appear may be challenged to provide the observed tendency in the behavior of the resonance frequency at increasing acoustic pressure. The conclusion is drawn that the further development of shell models could be improved by the consideration of nonlinear rheological laws. PMID:18977009

  11. Propagating wave and irregular dynamics: Spatiotemporal patterns of cholinergic theta oscillations in neocortex, in vitro

    PubMed Central

    Bao, Weili; Wu, Jian-young

    2010-01-01

    Neocortical “theta” oscillation (5- 12 Hz) has been observed in animals and human subjects but little is known about how the oscillation is organized in the cortical intrinsic networks. Here we use voltage-sensitive dye and optical imaging to study a carbachol/bicuculline induced theta (~8 Hz) oscillation in rat neocortical slices. The imaging has large signal-to-noise ratio, allowing us to map the phase distribution over the neocortical tissue during the oscillation. The oscillation was organized as spontaneous epochs and each epoch was composed of a “first spike”, a “regular” period (with relatively stable frequency and amplitude) and an “irregular” period (with variable frequency and amplitude) of oscillations. During each cycle of the regular oscillation one wave of activation propagated horizontally (parallel to the cortical lamina) across the cortical section at a velocity of ~50 mm/sec. Vertically the activity was synchronized through all cortical layers. This pattern of one propagating wave associated with one oscillation cycle was seen during all the regular cycles. The oscillation frequency varied noticeably at two neighboring horizontal locations (330 μm apart), suggesting that the oscillation is locally organized and each local oscillator is about equal or less than 300 μm wide horizontally. During irregular oscillations the spatiotemporal patterns were complex and sometimes the vertical synchronization decomposed, suggesting a de-coupling among local oscillators. Our data suggested that neocortical theta oscillation is sustained by multiple local oscillators. The coupling regime among the oscillators may determine the spatiotemporal pattern and switching between propagating waves and irregular patterns. PMID:12612003

  12. Sustaining GHz oscillation of carbon nanotube based oscillators via a MHz frequency excitation

    NASA Astrophysics Data System (ADS)

    Motevalli, Benyamin; Taherifar, Neda; Zhe Liu, Jefferson

    2016-05-01

    There have been intensive studies to investigate the properties of gigahertz nano-oscillators based on multi-walled carbon nanotubes (MWCNTs). Many of these studies, however, revealed that the unique telescopic translational oscillations in such devices would damp quickly due to various energy dissipation mechanisms. This challenge remains the primary obstacle against its practical applications. Herein, we propose a design concept in which a GHz oscillation could be re-excited by a MHz mechanical motion. This design involves a triple-walled CNT, in which sliding of the longer inner tube at a MHz frequency can re-excite and sustain a GHz oscillation of the shorter middle tube. Our molecular dynamics (MD) simulations prove this design concept at ˜10 nm scale. A mathematical model is developed to explore the feasibility at a larger size scale. As an example, in an oscillatory system with the CNT’s length above 100 nm, the high oscillatory frequency range of 1.8-3.3 GHz could be excited by moving the inner tube at a much lower frequency of 53.4 MHz. This design concept together with the mechanical model could energize the development of GHz nano-oscillators in miniaturized electro-mechanical devices.

  13. Oscillations, networks, and their development: MEG connectivity changes with age.

    PubMed

    Schäfer, Carmen B; Morgan, Benjamin R; Ye, Annette X; Taylor, Margot J; Doesburg, Sam M

    2014-10-01

    Magnetoencephalographic (MEG) investigations of inter-regional amplitude correlations have yielded new insights into the organization and neurophysiology of resting-state networks (RSNs) first identified using fMRI. Inter-regional MEG amplitude correlations in adult RSNs have been shown to be most prominent in alpha and beta frequency ranges and to express strong congruence with RSN topologies found using fMRI. Despite such advances, little is known about how oscillatory connectivity in RSNs develops throughout childhood and adolescence. This study used a novel fMRI-guided MEG approach to investigate the maturation of resting-state amplitude correlations in physiologically relevant frequency ranges within and among six RSNs in 59 participants, aged 6-34 years. We report age-related increases in inter-regional amplitude correlations that were largest in alpha and beta frequency bands. In contrast to fMRI reports, these changes were observed both within and between the various RSNs analyzed. Our results provide the first evidence of developmental changes in spontaneous neurophysiological connectivity in source-resolved RSNs, which indicate increasing integration within and among intrinsic functional brain networks throughout childhood, adolescence, and early adulthood. Copyright © 2014 Wiley Periodicals, Inc.

  14. Characteristics of Radio-Frequency Circuits Utilizing Ferroelectric Capacitors

    NASA Technical Reports Server (NTRS)

    Eskridge, Michael; Gui, Xiao; MacLeod, Todd; Ho, Fat D.

    2011-01-01

    Ferroelectric capacitors, most commonly used in memory circuits and variable components, were studied in simple analog radio-frequency circuits such as the RLC resonator and Colpitts oscillator. The goal was to characterize the RF circuits in terms of frequency of oscillation, gain, etc, using ferroelectric capacitors. Frequencies of oscillation of both circuits were measured and studied a more accurate resonant frequency can be obtained using the ferroelectric capacitors. Many experiments were conducted and data collected. A model to simulate the experimental results will be developed. Discrepancies in gain and frequency in these RF circuits when conventional capacitors are replaced with ferroelectric ones were studied. These results will enable circuit designers to anticipate the effects of using ferroelectric components in their radio- frequency applications.

  15. Synchronized delta oscillations correlate with the resting-state functional MRI signal

    PubMed Central

    Lu, Hanbing; Zuo, Yantao; Gu, Hong; Waltz, James A.; Zhan, Wang; Scholl, Clara A.; Rea, William; Yang, Yihong; Stein, Elliot A.

    2007-01-01

    Synchronized low-frequency spontaneous fluctuations of the functional MRI (fMRI) signal have recently been applied to investigate large-scale neuronal networks of the brain in the absence of specific task instructions. However, the underlying neural mechanisms of these fluctuations remain largely unknown. To this end, electrophysiological recordings and resting-state fMRI measurements were conducted in α-chloralose-anesthetized rats. Using a seed-voxel analysis strategy, region-specific, anesthetic dose-dependent fMRI resting-state functional connectivity was detected in bilateral primary somatosensory cortex (S1FL) of the resting brain. Cortical electroencephalographic signals were also recorded from bilateral S1FL; a visual cortex locus served as a control site. Results demonstrate that, unlike the evoked fMRI response that correlates with power changes in the γ bands, the resting-state fMRI signal correlates with the power coherence in low-frequency bands, particularly the δ band. These data indicate that hemodynamic fMRI signal differentially registers specific electrical oscillatory frequency band activity, suggesting that fMRI may be able to distinguish the ongoing from the evoked activity of the brain. PMID:17991778

  16. Rhythmic Activity and Individual Variability in Recognition Memory: Theta Oscillations Correlate with Performance whereas Alpha Oscillations Correlate with ERPs.

    PubMed

    Chen, Yvonne Y; Caplan, Jeremy B

    2017-01-01

    During study trials of a recognition memory task, alpha (∼10 Hz) oscillations decrease, and concurrently, theta (4-8 Hz) oscillations increase when later memory is successful versus unsuccessful (subsequent memory effect). Likewise, at test, reduced alpha and increased theta activity are associated with successful memory (retrieval success effect). Here we take an individual-differences approach to test three hypotheses about theta and alpha oscillations in verbal, old/new recognition, measuring the difference in oscillations between hit trials and miss trials. First, we test the hypothesis that theta and alpha oscillations have a moderately mutually exclusive relationship; but no support for this hypothesis was found. Second, we test the hypothesis that theta oscillations explain not only memory effects within participants, but also individual differences. Supporting this prediction, durations of theta (but not alpha) oscillations at study and at test correlated significantly with d' across participants. Third, we test the hypothesis that theta and alpha oscillations reflect familiarity and recollection processes by comparing oscillation measures to ERPs that are implicated in familiarity and recollection. The alpha-oscillation effects correlated with some ERP measures, but inversely, suggesting that the actions of alpha oscillations on memory processes are distinct from the roles of familiarity- and recollection-linked ERP signals. The theta-oscillation measures, despite differentiating hits from misses, did not correlate with any ERP measure; thus, theta oscillations may reflect elaborative processes not tapped by recollection-related ERPs. Our findings are consistent with alpha oscillations reflecting visual inattention, which can modulate memory, and with theta oscillations supporting recognition memory in ways that complement the most commonly studied ERPs.

  17. Temporal-spatial characteristics of phase-amplitude coupling in electrocorticogram for human temporal lobe epilepsy.

    PubMed

    Zhang, Ruihua; Ren, Ye; Liu, Chunyan; Xu, Na; Li, Xiaoli; Cong, Fengyu; Ristaniemi, Tapani; Wang, YuPing

    2017-09-01

    Neural activity of the epileptic human brain contains low- and high-frequency oscillations in different frequency bands, some of which have been used as reliable biomarkers of the epileptogenic brain areas. However, the relationship between the low- and high-frequency oscillations in different cortical areas during the period from pre-seizure to post-seizure has not been completely clarified. We recorded electrocorticogram data from the temporal lobe and hippocampus of seven patients with temporal lobe epilepsy. The modulation index based on the Kullback-Leibler distance and the phase-amplitude coupling co-modulogram were adopted to quantify the coupling strength between the phase of low-frequency oscillations (0.2-10Hz) and the amplitude of high-frequency oscillations (11-400Hz) in different seizure epochs. The time-varying phase-amplitude modulogram was used to analyze the phase-amplitude coupling pattern during the entire period from pre-seizure to post-seizure in both the left and right temporal lobe and hippocampus. Channels with strong modulation index were compared with the seizure onset channels identified by the neurosurgeons and the resection channels in the clinical surgery. The phase-amplitude coupling strength (modulation index) increased significantly in the mid-seizure epoch and decrease significantly in seizure termination and post-seizure epochs (p<0.001). The strong phase-amplitude-modulating low- and high-frequency oscillations in the mid-seizure epoch were mainly δ, θ, and α oscillations and γ and ripple oscillations, respectively. The phase-amplitude modulation and strength varied among channels and was asymmetrical in the left and right temporal cortex and hippocampus. The "fall-max" phase-amplitude modulation pattern, i.e., high-frequency amplitudes were largest in the low-frequency phase range [-π, 0], which corresponded to the falling edges of low-frequency oscillations, appeared in the middle period of the seizures at epileptic focus channels. Channels with strong modulation index appeared on the corresponding left or right temporal cortex of surgical resection and overlapped with the clinical resection zones in all patients. The "fall-max" pattern between the phase of low-frequency oscillation and amplitude of high-frequency oscillation that appeared in the middle period of the seizures is a reliable biomarker in epileptogenic cortical areas. The modulation index can be used as a good tool for lateralization and localization for the epileptic focus in patients with epilepsy. Phase-amplitude coupling can provide meaningful reference for accurate resection of epileptogenic focus and provide insight into the underlying neural dynamics of the epileptic seizure in patients with temporal lobe epilepsy. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

  18. Dynamics of Relaxation Processes of Spontaneous Otoacoustic Emissions

    NASA Astrophysics Data System (ADS)

    Murphy, William James

    The dynamical response of spontaneous otoacoustic emissions (SOAEs) to suppression by ipsilateral pulsed external tones of different frequencies and levels is investigated in nine female subjects under normal conditions and in four female subjects during periods when aspirin is being administered. A simple Van der Pol limit-cycle oscillator driven by an external tone is used as an interpretive model. Typical results for both the onset of, and recovery from suppression yield 1/r_1 (where -r_1 is the negative linear component of the damping function) in the range of 2-25 msec. In accordance with the predictions of the model: (a) the relaxation time for the onset of suppression increases with the amount of suppression induced by the external tone, (b) the values of r _1 and the amplitudes of the unsuppressed emissions exhibit an inverse correlation, (c) the values inferred for r_1 are not significantly dependent on the frequency of the pulsed suppressor tone and (d) the inferred r_1 values are not significantly dependent upon the amount of suppression. In investigations involving subjects under aspirin administration, the changes in the relaxation time constants indicate that the main effect of aspirin administration is to reduce the negative damping parameter r_1. The salicylate is apparently not metabolized in some subjects whose emissions are negligibly affected by aspirin administration. A modification of the single-oscillator model is used to describe pulsed suppression data obtained from a primary SOAE (2545 Hz) which is suppressed by a neighboring secondary emission (2895 Hz). The response of the SOAE amplitude during pulsed suppression is modeled by a pair of Van der Pol limit-cycle oscillators with the primary oscillator linearly coupled to the displacement of the secondary higher-frequency one. The relaxation time constants for the onset of, and recovery from, suppression are 4.5 and 4.8 msec, respectively, for the primary SOAE and 7.5 and 10.5 msec for the secondary one. Aspirin administration reduces the magnitude of the overshoot by reducing the level of the higher frequency SOAE and thereby eliminating the suppression of the lower frequency one.

  19. A biorobotic model of the human larynx.

    PubMed

    Manti, M; Cianchetti, M; Nacci, A; Ursino, F; Laschi, C

    2015-08-01

    This work focuses on a physical model of the human larynx that replicates its main components and functions. The prototype reproduces the multilayer vocal folds and the ab/adduction movements. In particular, the vocal folds prototype is made with soft materials whose mechanical properties have been obtained to be similar to the natural tissue in terms of viscoelasticity. A computational model was used to study fluid-structure interaction between vocal folds and the airflow. This tool allowed us to make a comparison between theoretical and experimental results. Measurements were performed with this prototype in an experimental platform comprising a controlled air flow, pressure sensors and a high-speed camera for measuring vocal fold vibrations. Data included oscillation frequency at the onset pressure and glottal width. Results show that the combination between vocal fold geometry, mechanical properties and dimensions exhibits an oscillation frequency close to that of the human vocal fold. Moreover, computational results show a high correlation with the experimental one.

  20. High frequency pressure oscillator for microcryocoolers.

    PubMed

    Vanapalli, S; ter Brake, H J M; Jansen, H V; Zhao, Y; Holland, H J; Burger, J F; Elwenspoek, M C

    2008-04-01

    Microminiature pulse tube cryocoolers should operate at a frequency of an order higher than the conventional macro ones because the pulse tube cryocooler operating frequency scales inversely with the square of the pulse tube diameter. In this paper, the design and experiments of a high frequency pressure oscillator is presented with the aim to power a micropulse tube cryocooler operating between 300 and 80 K, delivering a cooling power of 10 mW. Piezoelectric actuators operate efficiently at high frequencies and have high power density making them good candidates as drivers for high frequency pressure oscillator. The pressure oscillator described in this work consists of a membrane driven by a piezoelectric actuator. A pressure ratio of about 1.11 was achieved with a filling pressure of 2.5 MPa and compression volume of about 22.6 mm(3) when operating the actuator with a peak-to-peak sinusoidal voltage of 100 V at a frequency of 1 kHz. The electrical power input was 2.73 W. The high pressure ratio and low electrical input power at high frequencies would herald development of microminiature cryocoolers.

  1. High frequency pressure oscillator for microcryocoolers

    NASA Astrophysics Data System (ADS)

    Vanapalli, S.; ter Brake, H. J. M.; Jansen, H. V.; Zhao, Y.; Holland, H. J.; Burger, J. F.; Elwenspoek, M. C.

    2008-04-01

    Microminiature pulse tube cryocoolers should operate at a frequency of an order higher than the conventional macro ones because the pulse tube cryocooler operating frequency scales inversely with the square of the pulse tube diameter. In this paper, the design and experiments of a high frequency pressure oscillator is presented with the aim to power a micropulse tube cryocooler operating between 300 and 80K, delivering a cooling power of 10mW. Piezoelectric actuators operate efficiently at high frequencies and have high power density making them good candidates as drivers for high frequency pressure oscillator. The pressure oscillator described in this work consists of a membrane driven by a piezoelectric actuator. A pressure ratio of about 1.11 was achieved with a filling pressure of 2.5MPa and compression volume of about 22.6mm3 when operating the actuator with a peak-to-peak sinusoidal voltage of 100V at a frequency of 1kHz. The electrical power input was 2.73W. The high pressure ratio and low electrical input power at high frequencies would herald development of microminiature cryocoolers.

  2. Automatic oscillator frequency control system

    NASA Technical Reports Server (NTRS)

    Smith, S. F. (Inventor)

    1985-01-01

    A frequency control system makes an initial correction of the frequency of its own timing circuit after comparison against a frequency of known accuracy and then sequentially checks and corrects the frequencies of several voltage controlled local oscillator circuits. The timing circuit initiates the machine cycles of a central processing unit which applies a frequency index to an input register in a modulo-sum frequency divider stage and enables a multiplexer to clock an accumulator register in the divider stage with a cyclical signal derived from the oscillator circuit being checked. Upon expiration of the interval, the processing unit compares the remainder held as the contents of the accumulator against a stored zero error constant and applies an appropriate correction word to a correction stage to shift the frequency of the oscillator being checked. A signal from the accumulator register may be used to drive a phase plane ROM and, with periodic shifts in the applied frequency index, to provide frequency shift keying of the resultant output signal. Interposition of a phase adder between the accumulator register and phase plane ROM permits phase shift keying of the output signal by periodic variation in the value of a phase index applied to one input of the phase adder.

  3. Experimental study of the influence of low frequency flow modulation on the whistling behavior of a corrugated pipe.

    PubMed

    Kristiansen, Ulf R; Mattei, Pierre-Olivier; Pinhede, Cedric; Amielh, Muriel

    2011-10-01

    It is well known that airflow in a corrugated pipe can excite whistling at the frequencies of the pipe's longitudinal acoustic modes. This short contribution reports on the results of experiments where a low frequency, oscillating flow with velocity magnitudes of the same order as the airflow has been added. Depending on the oscillation strength, it has been found that this flow may silence the pipe or move the whistling to higher harmonics. It is also shown that the low frequency oscillation itself may excite higher frequency whistling sounds in the pipe. © 2011 Acoustical Society of America

  4. A class of parametrically excited calcium oscillation detectors.

    PubMed Central

    Izu, L T; Spangler, R A

    1995-01-01

    Intracellular Ca2+ oscillations are often a response to external signals such as hormones. Changes in the external signal can alter the frequency, amplitude, or form of the oscillations suggesting that information is encoded in the pattern of Ca2+ oscillations. How might a cell decode this signal? We show that an excitable system whose kinetic parameters are modulated by the Ca2+ concentration can function as a Ca2+ oscillation detector. Such systems have the following properties: (1) They are more sensitive to an oscillatory than to a steady Ca2+ signal. (2) Their response is largely independent of the signal amplitude. (3) They can extract information from a noisy signal. (4) Unlike other frequency sensitive detectors, they have a flat frequency response. These properties make a Ca(2+)-sensitive excitable system nearly ideal for detecting and decoding Ca2+ oscillations. We suggest that Ca2+ oscillations, in concert with these detectors, can act as cellular timekeepers to coordinate related biochemical reactions and enhance their overall efficiency. PMID:7787048

  5. Thin-film piezoelectric-on-silicon resonators for high-frequency reference oscillator applications.

    PubMed

    Abdolvand, Reza; Lavasani, Hossein M; Ho, Gavin K; Ayazi, Farrokh

    2008-12-01

    This paper studies the application of lateral bulk acoustic thin-film piezoelectric-on-substrate (TPoS) resonators in high-frequency reference oscillators. Low-motional-impedance TPoS resonators are designed and fabricated in 2 classes--high-order and coupled-array. Devices of each class are used to assemble reference oscillators and the performance characteristics of the oscillators are measured and discussed. Since the motional impedance of these devices is small, the transimpedance amplifier (TIA) in the oscillator loop can be reduced to a single transistor and 3 resistors, a format that is very power-efficient. The lowest reported power consumption is approximately 350 microW for an oscillator operating at approximately 106 MHz. A passive temperature compensation method is also utilized by including the buried oxide layer of the silicon-on-insulator (SOI) substrate in the structural resonant body of the device, and a very small (-2.4 ppm/ degrees C) temperature coefficient of frequency is obtained for an 82-MHz oscillator.

  6. Emergence of amplitude and oscillation death in identical coupled oscillators.

    PubMed

    Zou, Wei; Senthilkumar, D V; Duan, Jinqiao; Kurths, Jürgen

    2014-09-01

    We deduce rigorous conditions for the onset of amplitude death (AD) and oscillation death (OD) in a system of identical coupled paradigmatic Stuart-Landau oscillators. A nonscalar coupling and high frequency are beneficial for the onset of AD. In strong contrast, scalar diffusive coupling and low intrinsic frequency are in favor of the emergence of OD. Our finding contributes to clearly distinguish intrinsic geneses for AD and OD, and further substantially corroborates that AD and OD are indeed two dynamically distinct oscillation quenching phenomena due to distinctly different mechanisms.

  7. Continuous High Frequency Activity: A peculiar SEEG pattern related to specific brain regions

    PubMed Central

    Melani, Federico; Zelmann, Rina; Mari, Francesco; Gotman, Jean

    2015-01-01

    Objective While visually marking the high frequency oscillations in the stereo-EEG of epileptic patients, we observed a continuous/semicontinuous activity in the ripple band (80–250 Hz), which we defined continuous High Frequency Activity (HFA). We aim to analyze in all brain regions the occurrence and significance of this particular pattern. Methods Twenty patients implanted in mesial temporal and neocortical areas were studied. One minute of slow-wave sleep was reviewed. The background was classified as continuous/semicontinuous, irregular, or sporadic based on the duration of the fast oscillations. Each channel was classified as inside/outside the seizure onset zone (SOZ) or a lesion. Results The continuous/semicontinuous HFA occurred in 54 of the 790 channels analyzed, with a clearly higher prevalence in hippocampus and occipital lobe. No correlation was found with the SOZ or lesions. In the occipital lobe the continuous/semicontinuous HFA was present independently of whether eyes were open or closed. Conclusions We describe what appears to be a new physiological High Frequency Activity, independent of epileptogenicity, present almost exclusively in the hippocampus and occipital cortex but independent of the alpha rhythm. Significance The continuous HFA may be an intrinsic characteristic of specific brain regions, reflecting a particular type of physiological neuronal activity. PMID:23768436

  8. Vibrational dephasing in matter-wave interferometers

    NASA Astrophysics Data System (ADS)

    Rembold, A.; Schütz, G.; Röpke, R.; Chang, W. T.; Hwang, I. S.; Günther, A.; Stibor, A.

    2017-03-01

    Matter-wave interferometry is a highly sensitive tool to measure small perturbations in a quantum system. This property allows the creation of precision sensors for dephasing mechanisms such as mechanical vibrations. They are a challenge for phase measurements under perturbing conditions that cannot be perfectly decoupled from the interferometer, e.g. for mobile interferometric devices or vibrations with a broad frequency range. Here, we demonstrate a method based on second-order correlation theory in combination with Fourier analysis, to use an electron interferometer as a sensor that precisely characterizes the mechanical vibration spectrum of the interferometer. Using the high spatial and temporal single-particle resolution of a delay line detector, the data allows to reveal the original contrast and spatial periodicity of the interference pattern from ‘washed-out’ matter-wave interferograms that have been vibrationally disturbed in the frequency region between 100 and 1000 Hz. Other than with electromagnetic dephasing, due to excitations of higher harmonics and additional frequencies induced from the environment, the parts in the setup oscillate with frequencies that can be different to the applied ones. The developed numerical search algorithm is capable to determine those unknown oscillations and corresponding amplitudes. The technique can identify vibrational dephasing and decrease damping and shielding requirements in electron, ion, neutron, atom and molecule interferometers that generate a spatial fringe pattern on the detector plane.

  9. Early cognitive and language skills are linked to resting frontal gamma power across the first 3 years.

    PubMed

    Benasich, April A; Gou, Zhenkun; Choudhury, Naseem; Harris, Kenneth D

    2008-12-22

    High-frequency cortical activity in humans and animals has been linked to a wide variety of higher cognitive processes. This research suggests that specific changes in neuronal synchrony occur during cognitive processing, distinguished by emergence of fast oscillations in the gamma frequency range. To determine whether the development of high-frequency brain oscillations can be related to the development of cognitive abilities, we studied the power spectra of resting EEG in children 16, 24 and 36 months of age. Individual differences in the distribution of frontal gamma power during rest were highly correlated with concurrent language and cognitive skills at all ages. Gamma power was also associated with attention measures; children who were observed as having better inhibitory control and more mature attention shifting abilities had higher gamma power density functions. We included a group of children with a family history of language impairment (FH+) and thus at higher risk for language disorders. FH+ children, as a group, showed consistently lower gamma over frontal regions than the well-matched FH- controls with no such family history (FH-). We suggest that the emergence of high-frequency neural synchrony may be critical for cognitive and linguistic development, and that children at risk for language impairments may lag in this process.

  10. Timing Studies of X Persei and the Discovery of Its Transient Quasi-periodic Oscillation Feature

    NASA Technical Reports Server (NTRS)

    Acuner, Z.; Inam,S. C.; Sahiner, S.; Serim, M. M.; Baykal, A.; Swank, J.

    2014-01-01

    We present a timing analysis of X Persei (X Per) using observations made between 1998 and 2010 with the Proportional Counter Array (PCA) onboard the Rossi X-ray Timing Explorer (RXTE) and with the INTEGRAL Soft Gamma-Ray Imager (ISGRI). All pulse arrival times obtained from the RXTE-PCA observations are phase-connected and a timing solution is obtained using these arrival times. We update the long-term pulse frequency history of the source by measuring its pulse frequencies using RXTE-PCA and ISGRI data. From the RXTEPCA data, the relation between the frequency derivative and X-ray flux suggests accretion via the companion's stellar wind. However, the detection of a transient quasi-periodic oscillation feature, peaking at approximately 0.2 Hz, suggests the existence of an accretion disc. We find that doublebreak models fit the average power spectra well, which suggests that the source has at least two different accretion flow components dominating the overall flow. From the power spectrum of frequency derivatives, we measure a power-law index of approximately - 1, which implies that, on short time-scales, disc accretion dominates over noise, while on time-scales longer than the viscous time-scales, the noise dominates. From pulse profiles, we find a correlation between the pulse fraction and the count rate of the source.

  11. Anatomical and functional assemblies of brain BOLD oscillations

    PubMed Central

    Baria, Alexis T.; Baliki, Marwan N.; Parrish, Todd; Apkarian, A. Vania

    2011-01-01

    Brain oscillatory activity has long been thought to have spatial properties, the details of which are unresolved. Here we examine spatial organizational rules for the human brain oscillatory activity as measured by blood oxygen level-dependent (BOLD). Resting state BOLD signal was transformed into frequency space (Welch’s method), averaged across subjects, and its spatial distribution studied as a function of four frequency bands, spanning the full bandwidth of BOLD. The brain showed anatomically constrained distribution of power for each frequency band. This result was replicated on a repository dataset of 195 subjects. Next, we examined larger-scale organization by parceling the neocortex into regions approximating Brodmann Areas (BAs). This indicated that BAs of simple function/connectivity (unimodal), vs. complex properties (transmodal), are dominated by low frequency BOLD oscillations, and within the visual ventral stream we observe a graded shift of power to higher frequency bands for BAs further removed from the primary visual cortex (increased complexity), linking frequency properties of BOLD to hodology. Additionally, BOLD oscillation properties for the default mode network demonstrated that it is composed of distinct frequency dependent regions. When the same analysis was performed on a visual-motor task, frequency-dependent global and voxel-wise shifts in BOLD oscillations could be detected at brain sites mostly outside those identified with general linear modeling. Thus, analysis of BOLD oscillations in full bandwidth uncovers novel brain organizational rules, linking anatomical structures and functional networks to characteristic BOLD oscillations. The approach also identifies changes in brain intrinsic properties in relation to responses to external inputs. PMID:21613505

  12. Rocket Chamber Temperature Measurements by Microwave Techniques

    DTIC Science & Technology

    1974-07-01

    acoustic oscillation inside a cylindrical end burner la theoretically derived and experimentally observed. It.« oscillation frequencies observed range...from 3.2 to 4.4 kHz, whereas the theoretic?! oscillation frequencies range from 2.98 to 5.13 kHz for various oscillation modes. Acoustic gain and...loss expressions are derived and applied to the rocket firings. The results show that for a atable system, the acoustic loss exceed« the acoustic

  13. An X-band phase-locked relativistic backward wave oscillator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Y.; Science and Technology on High Power Microwave Laboratory, Mianyang 621900; Li, Z. H.

    2015-08-15

    For the purpose of coherent high power microwave combining at high frequency band, an X-band phase-locked relativistic backward wave oscillator is presented and investigated. The phase-locking of the oscillator is accomplished by modulation of the electron beam before it reaches the oscillator. To produce a bunched beam with an acceptable injected RF power requirement, an overmoded input cavity is employed to provide initial density modulation. And a buncher cavity is introduced to further increase the modulation depth. When the beam enters the oscillator, the modulation depth is enough to lock the frequency and phase of the output microwave generated bymore » the oscillator. Particle-in-cell simulation shows that an input power of 90 kW is sufficient to lock the frequency and phase of 1.5 GW output microwave with locking bandwidth of 60 MHz.« less

  14. Coherent Phonon Rabi Oscillations with a High-Frequency Carbon Nanotube Phonon Cavity.

    PubMed

    Zhu, Dong; Wang, Xin-He; Kong, Wei-Cheng; Deng, Guang-Wei; Wang, Jiang-Tao; Li, Hai-Ou; Cao, Gang; Xiao, Ming; Jiang, Kai-Li; Dai, Xing-Can; Guo, Guang-Can; Nori, Franco; Guo, Guo-Ping

    2017-02-08

    Phonon-cavity electromechanics allows the manipulation of mechanical oscillations similar to photon-cavity systems. Many advances on this subject have been achieved in various materials. In addition, the coherent phonon transfer (phonon Rabi oscillations) between the phonon cavity mode and another oscillation mode has attracted many interest in nanoscience. Here, we demonstrate coherent phonon transfer in a carbon nanotube phonon-cavity system with two mechanical modes exhibiting strong dynamical coupling. The gate-tunable phonon oscillation modes are manipulated and detected by extending the red-detuned pump idea of photonic cavity electromechanics. The first- and second-order coherent phonon transfers are observed with Rabi frequencies 591 and 125 kHz, respectively. The frequency quality factor product fQ m ∼ 2 × 10 12 Hz achieved here is larger than k B T base /h, which may enable the future realization of Rabi oscillations in the quantum regime.

  15. Experimental study on the flow separation and self-excited oscillation phenomenon in a rectangular duct

    NASA Astrophysics Data System (ADS)

    Xiong, Bing; Wang, Zhen-Guo; Fan, Xiao-Qiang; Wang, Yi

    2017-04-01

    To study the characteristics of flow separation and self-excited oscillation of a shock train in a rectangular duct, a simple test case has been conducted and analyzed. The high-speed Schlieren technique and high-frequency pressure measurements have been adopted to collect the data. The experimental results show that there are two separation modes in the duct under M3 incoming condition. The separation mode switch has great effects on the flow effects, such as the pressure distribution, the standard deviation distribution and so on. The separation mode switch can be judged by the history of pressure standard deviation. When it comes to the self-excited oscillation of a shock train, the frequency contents in the undisturbed region, the intermittent region, and the separated bubble have been compared. It was found that the low-frequency disturbance induced by the upstream shock foot motions can travel downstream and the frequency will be magnified by the separation bubble. The oscillation of the small shock foot and the oscillation of the large shock foot are associated with each other rather than oscillating independently.

  16. A neural mass model of basal ganglia nuclei simulates pathological beta rhythm in Parkinson's disease

    NASA Astrophysics Data System (ADS)

    Liu, Fei; Wang, Jiang; Liu, Chen; Li, Huiyan; Deng, Bin; Fietkiewicz, Chris; Loparo, Kenneth A.

    2016-12-01

    An increase in beta oscillations within the basal ganglia nuclei has been shown to be associated with movement disorder, such as Parkinson's disease. The motor cortex and an excitatory-inhibitory neuronal network composed of the subthalamic nucleus (STN) and the external globus pallidus (GPe) are thought to play an important role in the generation of these oscillations. In this paper, we propose a neuron mass model of the basal ganglia on the population level that reproduces the Parkinsonian oscillations in a reciprocal excitatory-inhibitory network. Moreover, it is shown that the generation and frequency of these pathological beta oscillations are varied by the coupling strength and the intrinsic characteristics of the basal ganglia. Simulation results reveal that increase of the coupling strength induces the generation of the beta oscillation, as well as enhances the oscillation frequency. However, for the intrinsic properties of each nucleus in the excitatory-inhibitory network, the STN primarily influences the generation of the beta oscillation while the GPe mainly determines its frequency. Interestingly, describing function analysis applied on this model theoretically explains the mechanism of pathological beta oscillations.

  17. Dynamical Fano-Like Interference between Rabi Oscillations and Coherent Phonons in a Semiconductor Microcavity System.

    PubMed

    Yoshino, S; Oohata, G; Mizoguchi, K

    2015-10-09

    We report on dynamical interference between short-lived Rabi oscillations and long-lived coherent phonons in CuCl semiconductor microcavities resulting from the coupling between the two oscillations. The Fourier-transformed spectra of the time-domain signals obtained from semiconductor microcavities by using a pump-probe technique show that the intensity of the coherent longitudinal optical phonon of CuCl is enhanced by increasing that of the Rabi oscillation, which indicates that the coherent phonon is driven by the Rabi oscillation through the Fröhlich interaction. Moreover, as the Rabi oscillation frequency decreases upon crossing the phonon frequency, the spectral profile of the coherent phonon changes from a peak to a dip with an asymmetric structure. The continuous wavelet transformation reveals that these peak and dip structures originate from constructive and destructive interference between Rabi oscillations and coherent phonons, respectively. We demonstrate that the asymmetric spectral structures in relation to the frequency detuning are well reproduced by using a classical coupled oscillator model on the basis of dynamical Fano-like interference.

  18. Sustainable limitation of high-frequency oscillations of elevator cabin

    NASA Astrophysics Data System (ADS)

    Kaytukov, Batraz

    2017-10-01

    In this paper, a problem of sustainable limitation of vertical high-frequency oscillations of elevator cabin in buildings with various number of storeys is considered. To solve this problem, dynamic model of the elevator movement was developed. In the course of analytical and experimental studies, the main cause for emergence of undesirable high-frequency oscillations of a cabin was defined. The amplification factor which is the function of λ and length of cable was determined. The λ parameter is variable, and length of the cable changes depending on length passed by the cabin and is an amplification factor argument. For sustainable limitation of oscillations, use of dynamic dumper of lever type is proposed. Adjustment of the dumper natural vibration frequency in such a way that it is equal to the excitation frequency allows limiting of oscillations of the cabin and the elevator machine to reasonable value irrespective to position of a moving cabin in the shaft. Using dependences and plots which were obtained in the course of scientific analysis and experimental studies, reasonability of dumper application for sustainable limitation of high-frequency influence of the elevator machine on the base and obtaining of solutions of inertial forces equilibration problem was proved.

  19. Integrated optoelectronic oscillator.

    PubMed

    Tang, Jian; Hao, Tengfei; Li, Wei; Domenech, David; Baños, Rocio; Muñoz, Pascual; Zhu, Ninghua; Capmany, José; Li, Ming

    2018-04-30

    With the rapid development of the modern communication systems, radar and wireless services, microwave signal with high-frequency, high-spectral-purity and frequency tunability as well as microwave generator with light weight, compact size, power-efficient and low cost are increasingly demanded. Integrated microwave photonics (IMWP) is regarded as a prospective way to meet these demands by hybridizing the microwave circuits and the photonics circuits on chip. In this article, we propose and experimentally demonstrate an integrated optoelectronic oscillator (IOEO). All of the devices needed in the optoelectronic oscillation loop circuit are monolithically integrated on chip within size of 5×6cm 2 . By tuning the injection current to 44 mA, the output frequency of the proposed IOEO is located at 7.30 GHz with phase noise value of -91 dBc/Hz@1MHz. When the injection current is increased to 65 mA, the output frequency can be changed to 8.87 GHz with phase noise value of -92 dBc/Hz@1MHz. Both of the oscillation frequency can be slightly tuned within 20 MHz around the center oscillation frequency by tuning the injection current. The method about improving the performance of IOEO is carefully discussed at the end of in this article.

  20. Frequency stability and offset locking of a laser-diode-pumped Nd:YAG monolithic nonplanar ring oscillator

    NASA Technical Reports Server (NTRS)

    Kane, Thomas J.; Nilsson, Alan C.; Byer, Robert L.

    1987-01-01

    The frequency stability of laser-diode-pumped, monolithic Nd:YAG solid-state unidirectional nonplanar ring oscillators was studied by heterodyne measurements. CW single-axial- and transverse-mode power of 25 mW at 1064 nm was obtained at a slope efficiency of 19 percent. Two independent oscillators were offset-locked at 17 MHz with frequency fluctuations of less than + or - 40 kHz for periods of 8 min.

  1. Input-dependent frequency modulation of cortical gamma oscillations shapes spatial synchronization and enables phase coding.

    PubMed

    Lowet, Eric; Roberts, Mark; Hadjipapas, Avgis; Peter, Alina; van der Eerden, Jan; De Weerd, Peter

    2015-02-01

    Fine-scale temporal organization of cortical activity in the gamma range (∼25-80Hz) may play a significant role in information processing, for example by neural grouping ('binding') and phase coding. Recent experimental studies have shown that the precise frequency of gamma oscillations varies with input drive (e.g. visual contrast) and that it can differ among nearby cortical locations. This has challenged theories assuming widespread gamma synchronization at a fixed common frequency. In the present study, we investigated which principles govern gamma synchronization in the presence of input-dependent frequency modulations and whether they are detrimental for meaningful input-dependent gamma-mediated temporal organization. To this aim, we constructed a biophysically realistic excitatory-inhibitory network able to express different oscillation frequencies at nearby spatial locations. Similarly to cortical networks, the model was topographically organized with spatially local connectivity and spatially-varying input drive. We analyzed gamma synchronization with respect to phase-locking, phase-relations and frequency differences, and quantified the stimulus-related information represented by gamma phase and frequency. By stepwise simplification of our models, we found that the gamma-mediated temporal organization could be reduced to basic synchronization principles of weakly coupled oscillators, where input drive determines the intrinsic (natural) frequency of oscillators. The gamma phase-locking, the precise phase relation and the emergent (measurable) frequencies were determined by two principal factors: the detuning (intrinsic frequency difference, i.e. local input difference) and the coupling strength. In addition to frequency coding, gamma phase contained complementary stimulus information. Crucially, the phase code reflected input differences, but not the absolute input level. This property of relative input-to-phase conversion, contrasting with latency codes or slower oscillation phase codes, may resolve conflicting experimental observations on gamma phase coding. Our modeling results offer clear testable experimental predictions. We conclude that input-dependency of gamma frequencies could be essential rather than detrimental for meaningful gamma-mediated temporal organization of cortical activity.

  2. Input-Dependent Frequency Modulation of Cortical Gamma Oscillations Shapes Spatial Synchronization and Enables Phase Coding

    PubMed Central

    Lowet, Eric; Roberts, Mark; Hadjipapas, Avgis; Peter, Alina; van der Eerden, Jan; De Weerd, Peter

    2015-01-01

    Fine-scale temporal organization of cortical activity in the gamma range (∼25–80Hz) may play a significant role in information processing, for example by neural grouping (‘binding’) and phase coding. Recent experimental studies have shown that the precise frequency of gamma oscillations varies with input drive (e.g. visual contrast) and that it can differ among nearby cortical locations. This has challenged theories assuming widespread gamma synchronization at a fixed common frequency. In the present study, we investigated which principles govern gamma synchronization in the presence of input-dependent frequency modulations and whether they are detrimental for meaningful input-dependent gamma-mediated temporal organization. To this aim, we constructed a biophysically realistic excitatory-inhibitory network able to express different oscillation frequencies at nearby spatial locations. Similarly to cortical networks, the model was topographically organized with spatially local connectivity and spatially-varying input drive. We analyzed gamma synchronization with respect to phase-locking, phase-relations and frequency differences, and quantified the stimulus-related information represented by gamma phase and frequency. By stepwise simplification of our models, we found that the gamma-mediated temporal organization could be reduced to basic synchronization principles of weakly coupled oscillators, where input drive determines the intrinsic (natural) frequency of oscillators. The gamma phase-locking, the precise phase relation and the emergent (measurable) frequencies were determined by two principal factors: the detuning (intrinsic frequency difference, i.e. local input difference) and the coupling strength. In addition to frequency coding, gamma phase contained complementary stimulus information. Crucially, the phase code reflected input differences, but not the absolute input level. This property of relative input-to-phase conversion, contrasting with latency codes or slower oscillation phase codes, may resolve conflicting experimental observations on gamma phase coding. Our modeling results offer clear testable experimental predictions. We conclude that input-dependency of gamma frequencies could be essential rather than detrimental for meaningful gamma-mediated temporal organization of cortical activity. PMID:25679780

  3. Sympathetic restraint of respiratory sinus arrhythmia: implications for vagal-cardiac tone assessment in humans

    NASA Technical Reports Server (NTRS)

    Taylor, J. A.; Myers, C. W.; Halliwill, J. R.; Seidel, H.; Eckberg, D. L.

    2001-01-01

    Clinicians and experimentalists routinely estimate vagal-cardiac nerve traffic from respiratory sinus arrhythmia. However, evidence suggests that sympathetic mechanisms may also modulate respiratory sinus arrhythmia. Our study examined modulation of respiratory sinus arrhythmia by sympathetic outflow. We measured R-R interval spectral power in 10 volunteers that breathed sequentially at 13 frequencies, from 15 to 3 breaths/min, before and after beta-adrenergic blockade. We fitted changes of respiratory frequency R-R interval spectral power with a damped oscillator model: frequency-dependent oscillations with a resonant frequency, generated by driving forces and modified by damping influences. beta-Adrenergic blockade enhanced respiratory sinus arrhythmia at all frequencies (at some, fourfold). The damped oscillator model fit experimental data well (39 of 40 ramps; r = 0.86 +/- 0.02). beta-Adrenergic blockade increased respiratory sinus arrhythmia by amplifying respiration-related driving forces (P < 0.05), without altering resonant frequency or damping influences. Both spectral power data and the damped oscillator model indicate that cardiac sympathetic outflow markedly reduces heart period oscillations at all frequencies. This challenges the notion that respiratory sinus arrhythmia is mediated simply by vagal-cardiac nerve activity. These results have important implications for clinical and experimental estimation of human vagal cardiac tone.

  4. [Are simple time lags responsible for cyclic variation of population density? : A comparison of laboratory population dynamics of Brachionus calyciflorus pallas (rotatoria) with computer simulations].

    PubMed

    Halbach, Udo; Burkhardt, Heinz Jürgen

    1972-09-01

    Laboratory populations of the rotifer Brachionus calyciflorus were cultured at different temperatures (25, 20, 15°C) but otherwise at constant conditions. The population densities showed relatively constant oscillations (Figs. 1 to 3A-C). Amplitudes and frequencies of the oscillations were positively correlated with temperature (Table 1). A test was made, whether the logistic growth function with simple time lag is able to describe the population curves. There are strong similarities between the simulations (Figs. 1-3E) and the real population dynamics if minor adjustments of the empirically determined parameters are made. There-fore it is suggested that time lags are responsible for the observed oscillations. However, the actual time lags probably do not act in the simple manner of the model, because birth and death rates react with different time lags, and both parameters are dependent on individual age and population density. A more complex model, which incorporates these modifications, should lead to a more realistic description of the observed oscillations.

  5. Evidence supporting a role for astrocytes in the regulation of cognitive flexibility and neuronal oscillations through the Ca2+ binding protein S100β.

    PubMed

    Brockett, Adam T; Kane, Gary A; Monari, Patrick K; Briones, Brandy A; Vigneron, Pierre-Antoine; Barber, Gabriela A; Bermudez, Andres; Dieffenbach, Uma; Kloth, Alexander D; Buschman, Timothy J; Gould, Elizabeth

    2018-01-01

    The medial prefrontal cortex (mPFC) is important for cognitive flexibility, the ability to switch between two task-relevant dimensions. Changes in neuronal oscillations and alterations in the coupling across frequency ranges have been correlated with attention and cognitive flexibility. Here we show that astrocytes in the mPFC of adult male Sprague Dawley rats, participate in cognitive flexibility through the astrocyte-specific Ca2+ binding protein S100β, which improves cognitive flexibility and increases phase amplitude coupling between theta and gamma oscillations. We further show that reduction of astrocyte number in the mPFC impairs cognitive flexibility and diminishes delta, alpha and gamma power. Conversely, chemogenetic activation of astrocytic intracellular Ca2+ signaling in the mPFC enhances cognitive flexibility, while inactivation of endogenous S100β among chemogenetically activated astrocytes in the mPFC prevents this improvement. Collectively, our work suggests that astrocytes make important contributions to cognitive flexibility and that they do so by releasing a Ca2+ binding protein which in turn enhances coordinated neuronal oscillations.

  6. Continuum modeling investigation of gigahertz oscillators based on a C60 fullerene inside cyclic peptide nanotubes

    NASA Astrophysics Data System (ADS)

    Sadeghi, F.; Ansari, R.; Darvizeh, M.

    2016-02-01

    Research concerning the fabrication of nano-oscillators with operating frequency in the gigahertz (GHz) range has become a focal point in recent years. In this paper, a new type of GHz oscillators is introduced based on a C60 fullerene inside a cyclic peptide nanotube (CPN). To study the dynamic behavior of such nano-oscillators, using the continuum approximation in conjunction with the 6-12 Lennard-Jones (LJ) potential function, analytical expressions are derived to determine the van der Waals (vdW) potential energy and interaction force between the two interacting molecules. Employing Newton's second law, the equation of motion is solved numerically to arrive at the telescopic oscillatory motion of a C60 fullerene inside CPNs. It is shown that the fullerene molecule exhibits different kinds of oscillation inside peptide nanotubes which are sensitive to the system parameters. Furthermore, for the precise evaluation of the oscillation frequency, a novel semi-analytical expression is proposed based on the conservation of the mechanical energy principle. Numerical results are presented to comprehensively study the effects of the number of peptide units and initial conditions (initial separation distance and velocity) on the oscillatory behavior of C60 -CPN oscillators. It is found out that for peptide nanotubes comprised of one unit, the maximum achievable frequency is obtained when the inner core oscillates with respect to its preferred positions located outside the tube, while for other numbers of peptide units, such frequency is obtained when the inner core oscillates with respect to the preferred positions situated in the space between the two first or the two last units. It is further found out that four peptide units are sufficient to obtain the optimal frequency.

  7. Phenomena of oscillations in atmospheric pressure direct current glow discharges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Fu-cheng; Yan, Wen; Wang, De-zhen

    2013-12-15

    Self-sustained oscillations in a dc glow discharge with a semiconductor layer at atmospheric pressure were investigated by means of a one-dimensional fluid model. It is found that the dc glow discharge initially becomes unstable in the subnormal glow region and gives rise to oscillations of plasma parameters. A variety of oscillations with one or more frequencies have been observed under different conditions. The discharge oscillates between the glow discharge mode and the Townsend discharge mode in the oscillations with large amplitude while operates in the subnormal glow discharge mode all the while in the oscillations with small amplitude. Fourier Transformmore » spectra of oscillations reveal the transition mechanism between different oscillations. The effects of semiconductor conductivity on the oscillation frequency of the dominant mode, gas voltage, as well as the discharge current have also been analyzed.« less

  8. Effect of external magnetic field on locking range of spintronic feedback nano oscillator

    NASA Astrophysics Data System (ADS)

    Singh, Hanuman; Konishi, K.; Bose, A.; Bhuktare, S.; Miwa, S.; Fukushima, A.; Yakushiji, K.; Yuasa, S.; Kubota, H.; Suzuki, Y.; Tulapurkar, A. A.

    2018-05-01

    In this work we have studied the effect of external applied magnetic field on the locking range of spintronic feedback nano oscillator. Injection locking of spintronic feedback nano oscillator at integer and fractional multiple of its auto oscillation frequency was demonstrated recently. Here we show that the locking range increases with increasing external magnetic field. We also show synchronization of spintronic feedback nano oscillator at integer (n=1,2,3) multiples of auto oscillation frequency and side band peaks at higher external magnetic field values. We have verified experimental results with macro-spin simulation using similar conditions as used for the experimental study.

  9. Study on ion energy distribution in low-frequency oscillation time scale of Hall thrusters

    NASA Astrophysics Data System (ADS)

    Wei, Liqiu; Li, Wenbo; Ding, Yongjie; Han, Liang; Yu, Daren; Cao, Yong

    2017-11-01

    This paper reports on the dynamic characteristics of the distribution of ion energy during Hall thruster discharge in the low-frequency oscillation time scale through experimental studies, and a statistical analysis of the time-varying peak and width of ion energy and the ratio of high-energy ions during the low-frequency oscillation. The results show that the ion energy distribution exhibits a periodic change during the low-frequency oscillation. Moreover, the variation in the ion energy peak is opposite to that of the discharge current, and the variations in width of the ion energy distribution and the ratio of high-energy ions are consistent with that of the discharge current. The variation characteristics of the ion density and discharge potential were simulated by one-dimensional hybrid-direct kinetic simulations; the simulation results and analysis indicate that the periodic change in the distribution of ion energy during the low-frequency oscillation depends on the relationship between the ionization source term and discharge potential distribution during ionization in the discharge channel.

  10. Indirect synchronization control in a starlike network of phase oscillators

    NASA Astrophysics Data System (ADS)

    Kuptsov, Pavel V.; Kuptsova, Anna V.

    2018-04-01

    A starlike network of non-identical phase oscillators is considered that contains the hub and tree rays each having a single node. In such network effect of indirect synchronization control is reported: changing the natural frequency and the coupling strength of one of the peripheral oscillators one can switch on an off the synchronization of the others. The controlling oscillator at that is not synchronized with them and has a frequency that is approximately four time higher then the frequency of the synchronization. The parameter planes showing a corresponding synchronization tongue are represented and time dependencies of phase differences are plotted for points within and outside of the tongue.

  11. Frequency quenching of microwave-induced resistance oscillations in a high-mobility two-dimensional electron gas

    NASA Astrophysics Data System (ADS)

    Studenikin, S. A.; Sachrajda, A. S.; Gupta, J. A.; Wasilewski, Z. R.; Fedorych, O. M.; Byszewski, M.; Maude, D. K.; Potemski, M.; Hilke, M.; West, K. W.; Pfeiffer, L. N.

    2007-10-01

    The frequency dependence of microwave-induced resistance oscillations (MIROs) has been studied experimentally in high-mobility electron GaAs/AlGaAs structures to explore the limits at which these oscillations can be observed. It is found that in dc transport experiments at frequencies above 120GHz , MIROs start to quench, while above 230GHz , they completely disappear. The results will need to be understood theoretically but are qualitatively discussed within a model in which forced electronic charge oscillations (plasmons) play an intermediate role in the interaction process between the radiation and the single-particle electron excitations between Landau levels.

  12. An Agile Beam Transmit Array Using Coupled Oscillator Phase Control

    NASA Technical Reports Server (NTRS)

    Pogorzelski, Ronald S.; Scaramastra, Rocco P.; Huang, John; Beckon, Robert J.; Petree, Steve M.; Chavez, Cosme

    1993-01-01

    A few years ago York and colleagues suggested that injection locking of voltage controlled oscillators could be used to implement beam steering in a phased array [I]. The scheme makes use of the fact that when an oscillator is injection locked to an external signal, the phase difference between the output of the oscillator and the injection signal is governed by the difference between the injection frequency and the free running frequency of the oscillator (the frequency to which the oscillator is tuned). Thus, if voltage controlled oscillators (VCOs) are used, this phase difference is controlled by an applied voltage. Now, if a set of such oscillators are coupled to nearest neighbors, they can be made to mutually injection lock and oscillate as an ensemble. If they are all tuned to the same frequency, they will all oscillate in phase. Thus, if the outputs are connected to radiating elements forming a linear array, the antenna will radiate normal to the line of elements. Scanning is accomplished by antisymmetrically detuning the end oscillators in the array by application of a pair of appropriate voltages to their tuning ports. This results in a linear phase progression across the array which is just the phasing required to scan the beam. The scan angle is determined by the degree of detuning. We have constructed a seven element one dimensional agile beam array at S-band based on the above principle. Although, a few such arrays have been built in the past, this array possesses two unique features. First, the VCO MMICs have buffer amplifiers which isolate the output from the tuning circuit, and second, the oscillators are weakly coupled to each other at their resonant circuits rather than their outputs. This results in a convenient isolation between the oscillator array design and the radiating aperture design. An important parameter in the design is the so called coupling phase which determines the phase shift of the signals passing from one oscillator to its neighbors. Using this array, we have been able to verify the theoretical predictions concerning the effect of this phase on both the locking range and ensemble frequency of the array. However, the scan range achieved fell somewhat short of the theoretical value because of the amplitude variation of the oscillator outputs with tuning.

  13. Wideband-frequency tunable optoelectronic oscillator based on injection locking to an electronic oscillator.

    PubMed

    Fleyer, Michael; Sherman, Alexander; Horowitz, Moshe; Namer, Moshe

    2016-05-01

    We experimentally demonstrate a wideband-frequency tunable optoelectronic oscillator (OEO) based on injection locking of the OEO to a tunable electronic oscillator. The OEO cavity does not contain a narrowband filter and its frequency can be tuned over a broad bandwidth of 1 GHz. The injection locking is based on minimizing the injected power by adjusting the frequency of one of the OEO cavity modes to be approximately equal to the frequency of the injected signal. The phase noise that is obtained in the injection-locked OEO is similar to that obtained in a long-cavity self-sustained OEO. Although the cavity length of the OEO was long, the spurious modes were suppressed due to the injection locking without the need to use a narrowband filter. The spurious level was significantly below that obtained in a self-sustained OEO after inserting a narrowband electronic filter with a Q-factor of 720 into the cavity.

  14. Value of electrical stimulation and high frequency oscillations (80–500 Hz) in identifying epileptogenic areas during intracranial EEG recordings

    PubMed Central

    Jacobs, Julia; Zijlmans, Maeike; Zelmann, Rina; Olivier, André; Hall, Jeffery; Gotman, Jean; Dubeau, François

    2013-01-01

    Summary Purpose Electrical stimulation (ES) is used during intracranial electroencephalography (EEG) investigations to delineate epileptogenic areas and seizure-onset zones (SOZs) by provoking afterdischarges (ADs) or patients’ typical seizure. High frequency oscillations (HFOs—ripples, 80–250 Hz; fast ripples, 250–500 Hz) are linked to seizure onset. This study investigates whether interictal HFOs are more frequent in areas with a low threshold to provoke ADs or seizures. Methods Intracranial EEG studies were filtered at 500 Hz and sampled at 2,000 Hz. HFOs were visually identified. Twenty patients underwent ES, with gradually increasing currents. Results were interpreted as agreeing or disagreeing with the intracranial study (clinical-EEG seizure onset defined the SOZ). Current thresholds provoking an AD or seizure were correlated with the rate of HFOs of each channel. Results ES provoked a seizure in 12 and ADs in 19 patients. Sixteen patients showed an ES response inside the SOZ, and 10 had additional areas with ADs. The response was more specific for mesiotemporal than for neocortical channels. HFO rates were negatively correlated with thresholds for ES responses; especially in neo-cortical regions; areas with low threshold and high HFO rate were colocalized even outside the SOZ. Discussion Areas showing epileptic HFOs colocalize with those reacting to ES. HFOs may represent a pathologic correlate of regions showing an ES response; both phenomena suggest a more widespread epileptogenicity. PMID:19845730

  15. On-chip microfluid induced by oscillation of microrobot for noncontact cell transportation

    NASA Astrophysics Data System (ADS)

    Feng, Lin; Liang, Shuzhang; Zhou, Xiangcong; Yang, Jianlei; Jiang, Yonggang; Zhang, Deyuan; Arai, Fumihito

    2017-11-01

    The importance of cell manipulation and cultivation is increasing rapidly in various fields, such as drug discovery, regenerative medicine, and investigation of new energy sources. This paper presents a method to transport cells in a microfluidic chip without contact. A local vortex was generated when high-frequency oscillation of a microtool was induced in a microfluidic chip. The vortex was controlled by tuning the tool's oscillation parameters, such as the oscillation amplitude and frequency. The cells were then transported in the chip based on the direction of the tool's movement, and their position, posture, and trajectories were controlled. Bovine oocyte manipulations, that is, transportation and rotation, were conducted to demonstrate the capability of the proposed method, without any contact by the microrobot with high-frequency oscillation.

  16. [The mechanism and function of hippocampal neural oscillation].

    PubMed

    Lu, Ning; Xing, Dan-Qin; Sheng, Tao; Lu, Wei

    2017-10-25

    Neural oscillation is rhythmic or repetitive neural activity in the central nervous system that is usually generated by oscillatory activity of neuronal ensembles, reflecting regular and synchronized activities within these cell populations. According to several oscillatory bands covering frequencies from approximately 0.5 Hz to >100 Hz, neural oscillations are usually classified as delta oscillation (0.5-3 Hz), theta oscillation (4-12 Hz), beta oscillation (12-30 Hz), gamma oscillation (30-100 Hz) and sharp-wave ripples (>100 Hz ripples superimposed on 0.01-3 Hz sharp waves). Neural oscillation in different frequencies can be detected in different brain regions of human and animal during perception, motion and sleep, and plays an essential role in cognition, learning and memory process. In this review, we summarize recent findings on neural oscillations in hippocampus, as well as the mechanism and function of hippocampal theta oscillation, gamma oscillation and sharp-wave ripples. This review may yield new insights into the functions of neural oscillation in general.

  17. Nonlinear Oscillators in Space Physics

    NASA Technical Reports Server (NTRS)

    Lester,Daniel; Thronson, Harley

    2011-01-01

    We discuss dynamical systems that produce an oscillation without an external time dependent source. Numerical results are presented for nonlinear oscillators in the Em1h's atmosphere, foremost the quasi-biennial oscillation (QBOl. These fluid dynamical oscillators, like the solar dynamo, have in common that one of the variables in a governing equation is strongly nonlinear and that the nonlinearity, to first order, has particular form. of 3rd or odd power. It is shown that this form of nonlinearity can produce the fundamental li'equency of the internal oscillation. which has a period that is favored by the dynamical condition of the fluid. The fundamental frequency maintains the oscillation, with no energy input to the system at that particular frequency. Nonlinearities of 2nd or even power could not maintain the oscillation.

  18. Frequency Shift During Mass Properties Testing Using Compound Pendulum Method

    NASA Technical Reports Server (NTRS)

    Wolfe, David; Regan, Chris

    2012-01-01

    During mass properties testing on the X-48B Blended Wing Body aircraft (The Boeing Company, Chicago, Illinois) at the National Aeronautics and Space Administration Dryden Flight Research Center, Edwards, California, large inertia measurement errors were observed in results from compound pendulum swings when compared to analytical models. By comparing periods of oscillations as measured from an average over the test period versus the period of each oscillation, it was noticed that the frequency of oscillation was shifting significantly throughout the test. This phenomenon was only noticed during compound pendulum swings, and not during bifilar pendulum swings. The frequency shift was only visible upon extensive data analysis of the frequency for each oscillation, and did not appear in averaged frequency data over the test period. Multiple test articles, test techniques, and hardware setups were used in attempts to eliminate or identify the cause of the frequency shift. Plotting the frequency of oscillation revealed a region of minimal shift that corresponded to a larger amplitude range. This region of minimal shift provided the most accurate results compared to a known test article; however, the amplitudes that produce accurate inertia measurements are amplitudes larger than those generally accepted in mass properties testing. This paper examines two case studies of the frequency shift, using mass properties testing performed on a dummy test article, and on the X-48B Blended Wing Body aircraft.

  19. Dynamic modulation of epileptic high frequency oscillations by the phase of slower cortical rhythms.

    PubMed

    Ibrahim, George M; Wong, Simeon M; Anderson, Ryan A; Singh-Cadieux, Gabrielle; Akiyama, Tomoyuki; Ochi, Ayako; Otsubo, Hiroshi; Okanishi, Tohru; Valiante, Taufik A; Donner, Elizabeth; Rutka, James T; Snead, O Carter; Doesburg, Sam M

    2014-01-01

    Pathological high frequency oscillations (pHFOs) have been proposed to be robust markers of epileptic cortex. Oscillatory activity below this frequency range has been shown to be modulated by phase of lower frequency oscillations. Here, we tested the hypothesis that dynamic cross-frequency interactions involving pHFOs are concentrated within the epileptogenic cortex. Intracranial electroencephalographic recordings from 17 children with medically-intractable epilepsy secondary to focal cortical dysplasia were obtained. A time-resolved analysis was performed to determine topographic concentrations and dynamic changes in cross-frequency amplitude-to-phase coupling (CFC). CFC between pHFOs and the phase of theta and alpha rhythms was found to be significantly elevated in the seizure-onset zone compared to non-epileptic regions (p<0.01). Data simulations showed that elevated CFC could not be attributed to the presence of sharp transients or other signal properties. The phase of low frequency oscillations at which pHFO amplitudes were maximal was inconsistent at seizure initiation, yet consistently at the trough of the low frequency rhythm at seizure termination. Amplitudes of pHFOs were most significantly modulated by the phase of alpha-band oscillations (p<0.01). These results suggest that increased CFC between pHFO amplitude and alpha phase may constitute a marker of epileptogenic brain areas and may be relevant for understanding seizure dynamics. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Numerical study of low-frequency discharge oscillations in a 5 kW Hall thruster

    NASA Astrophysics Data System (ADS)

    Le, YANG; Tianping, ZHANG; Juanjuan, CHEN; Yanhui, JIA

    2018-07-01

    A two-dimensional particle-in-cell plasma model is built in the R–Z plane to investigate the low-frequency plasma oscillations in the discharge channel of a 5 kW LHT-140 Hall thruster. In addition to the elastic, excitation, and ionization collisions between neutral atoms and electrons, the Coulomb collisions between electrons and electrons and between electrons and ions are analyzed. The sheath characteristic distortion is also corrected. Simulation results indicate the capability of the built model to reproduce the low-frequency oscillation with high accuracy. The oscillations of the discharge current and ion density produced by the model are consistent with the existing conclusions. The model predicts a frequency that is consistent with that calculated by the zero-dimensional theoretical model.

  1. Parametric Oscillation, Frequency Mixing, and Injection Locking of Strongly Coupled Nanomechanical Resonator Modes.

    PubMed

    Seitner, Maximilian J; Abdi, Mehdi; Ridolfo, Alessandro; Hartmann, Michael J; Weig, Eva M

    2017-06-23

    We study locking phenomena of two strongly coupled, high quality factor nanomechanical resonator modes to a common parametric drive at a single drive frequency in different parametric driving regimes. By controlled dielectric gradient forces we tune the resonance frequencies of the flexural in-plane and out-of-plane oscillation of the high stress silicon nitride string through their mutual avoided crossing. For the case of the strong common parametric drive signal-idler generation via nondegenerate parametric two-mode oscillation is observed. Broadband frequency tuning of the very narrow linewidth signal and idler resonances is demonstrated. When the resonance frequencies of the signal and idler get closer to each other, partial injection locking, injection pulling, and complete injection locking to half of the drive frequency occurs depending on the pump strength. Furthermore, satellite resonances, symmetrically offset from the signal and idler by their beat note, are observed, which can be attributed to degenerate four-wave mixing in the highly nonlinear mechanical oscillations.

  2. Early Oscillation Detection Technique for Hybrid DC/DC Converters

    NASA Technical Reports Server (NTRS)

    Wang, Bright L.

    2011-01-01

    Oscillation or instability is a situation that must be avoided for reliable hybrid DC/DC converters. A real-time electronics measurement technique was developed to detect catastrophic oscillations at early stages for hybrid DC/DC converters. It is capable of identifying low-level oscillation and determining the degree of the oscillation at a unique frequency for every individual model of the converters without disturbing their normal operations. This technique is specially developed for space-used hybrid DC/DC converters, but it is also suitable for most of commercial and military switching-mode power supplies. This is a weak-electronic-signal detection technique to detect hybrid DC/DC converter oscillation presented as a specific noise signal at power input pins. It is based on principles of feedback control loop oscillation and RF signal modulations, and is realized by using signal power spectral analysis. On the power spectrum, a channel power amplitude at characteristic frequency (CPcf) and a channel power amplitude at switching frequency (CPsw) are chosen as oscillation level indicators. If the converter is stable, the CPcf is a very small pulse and the CPsw is a larger, clear, single pulse. At early stage of oscillation, the CPcf increases to a certain level and the CPsw shows a small pair of sideband pulses around it. If the converter oscillates, the CPcf reaches to a higher level and the CPsw shows more high-level sideband pulses. A comprehensive stability index (CSI) is adopted as a quantitative measure to accurately assign a degree of stability to a specific DC/DC converter. The CSI is a ratio of normal and abnormal power spectral density, and can be calculated using specified and measured CPcf and CPsw data. The novel and unique feature of this technique is the use of power channel amplitudes at characteristic frequency and switching frequency to evaluate stability and identify oscillations at an early stage without interfering with a DC/DC converter s normal operation. This technique eliminates the probing problem of a gain/phase margin method by connecting the power input to a spectral analyzer. Therefore, it is able to evaluate stability for all kinds of hybrid DC/DC converters with or without remote sense pins, and is suitable for real-time and in-circuit testing. This frequency-domain technique is more sensitive to detect oscillation at early stage than the time-domain method using an oscilloscope.

  3. Acetylcholine modulates gamma frequency oscillations in the hippocampus by activation of muscarinic M1 receptors.

    PubMed

    Betterton, Ruth T; Broad, Lisa M; Tsaneva-Atanasova, Krasimira; Mellor, Jack R

    2017-06-01

    Modulation of gamma oscillations is important for the processing of information and the disruption of gamma oscillations is a prominent feature of schizophrenia and Alzheimer's disease. Gamma oscillations are generated by the interaction of excitatory and inhibitory neurons where their precise frequency and amplitude are controlled by the balance of excitation and inhibition. Acetylcholine enhances the intrinsic excitability of pyramidal neurons and suppresses both excitatory and inhibitory synaptic transmission, but the net modulatory effect on gamma oscillations is not known. Here, we find that the power, but not frequency, of optogenetically induced gamma oscillations in the CA3 region of mouse hippocampal slices is enhanced by low concentrations of the broad-spectrum cholinergic agonist carbachol but reduced at higher concentrations. This bidirectional modulation of gamma oscillations is replicated within a mathematical model by neuronal depolarisation, but not by reducing synaptic conductances, mimicking the effects of muscarinic M1 receptor activation. The predicted role for M1 receptors was supported experimentally; bidirectional modulation of gamma oscillations by acetylcholine was replicated by a selective M1 receptor agonist and prevented by genetic deletion of M1 receptors. These results reveal that acetylcholine release in CA3 of the hippocampus modulates gamma oscillation power but not frequency in a bidirectional and dose-dependent manner by acting primarily through muscarinic M1 receptors. © 2017 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  4. Autonomous and driven dynamics of spin torque nano-oscillators

    NASA Astrophysics Data System (ADS)

    Urazhdin, Sergei

    2012-02-01

    Understanding the dynamical properties of autonomous spin torque nano-oscillators (STNO) and their response to external perturbations is important for their applications as nanoscale microwave sources. We used spectroscopic measurements to study the dynamical characteristics of nanopillar- and point contact-based STNOs incorporating a microstrip in close proximity to the active magnetic layer. By applying microwave current at frequency fext to the microstrip, we were able to generate large microwave fields of more than 30 Oe rms at the location of STNO. We demonstrate that for a wide range of fext, STNO exhibits multiple synchronization regimes with integer and non-integer rational ratios between fext and the oscillation frequency f. We show that the synchronization ranges are determined by the symmetry of the oscillation orbit and the orientation of the driving field relative to the symmetry axis of the orbit. We observe synchronization hysteresis, i.e. a dependence of the synchronization limits on the dynamical history caused by the nonlinearity of STNO. We also show that the oscillation can be parametrically excited in the subcritical regime of STNO by a microwave field at twice the frequency of the oscillation. By measuring the threshold and the frequency range of parametric excitation, we determine damping, spin-polarization efficiency, and coupling to the microwave signal. In addition, by measuring the frequency range of parametric synchronization in the auto-oscillation regime, we determine the dynamic nonlinearity of the nanomagnet. Thus, analysis of the driven oscillations provides complete information about the dynamical characteristics of STNO. Finally, we discuss several unusual dynamical behaviors of STNO caused by their strong nonlinearity.

  5. On the Nature of the mHz X-Ray QPOs from ULX M82 X-1: Evidence for Timing-Spectral (anti) Correlation

    NASA Technical Reports Server (NTRS)

    Pasham, Dheeraj R.; Strohmayer, Tod E.

    2013-01-01

    Using all the archival XMM-Newton X-ray (3-10 keV) observations of the ultraluminous X-ray source (ULX) M82 X-1 we searched for a correlation between its variable mHz quasi-periodic oscillation (QPO) frequency and its energy spectral power-law index. These quantities are known to correlate in stellar mass black holes (StMBHs) exhibiting Type-C QPOs (approx 0.2-15 Hz). The detection of such a correlation would strengthen the identification of its mHz QPOs as Type-C and enable a more reliable mass estimate by scaling its QPO frequencies to those of Type-C QPOs in StMBHs of known mass. We resolved the count rates of M82 X-1 and a nearby bright ULX (source 5/X42.3+59) through surface brightness modeling and identify observations in which M82 X-1 was at least as bright as source 5. Using only those observations, we detect QPOs in the frequency range of 36-210 mHz during which the energy spectral power-law index varied from 1.7-2.2. Interestingly, we find evidence for an anti-correlation (Pearsons correlation coefficient = -0.95) between the power-law index and the QPO centroid frequency. While such an anti-correlation is observed in StMBHs at high Type-C QPO frequencies (approx 5-15 Hz), the frequency range over which it holds in StMBHs is significantly smaller (factor of approx 1.5-3) than the QPO range reported here from M82 X-1 (factor of 6). However, it remains possible that contamination from source 5 can bias our result. Joint Chandra/XMM-Newton observations in the future can resolve this problem and confirm the timing-spectral anti-correlation reported here.

  6. Relationships between atmospheric circulation indices and rainfall in Northern Algeria and comparison of observed and RCM-generated rainfall

    NASA Astrophysics Data System (ADS)

    Taibi, S.; Meddi, M.; Mahé, G.; Assani, A.

    2017-01-01

    This work aims, as a first step, to analyze rainfall variability in Northern Algeria, in particular extreme events, during the period from 1940 to 2010. Analysis of annual rainfall shows that stations in the northwest record a significant decrease in rainfall since the 1970s. Frequencies of rainy days for each percentile (5th, 10th, 25th, 50th, 75th, 90th, 95th, and 99th) and each rainfall interval class (1-5, 5-10, 10-20, 20-50, and ≥50 mm) do not show a significant change in the evolution of daily rainfall. The Tenes station is the only one to show a significant decrease in the frequency of rainy days up to the 75th percentile and for the 10-20-mm interval class. There is no significant change in the temporal evolution of extreme events in the 90th, 95th, and 99th percentiles. The relationships between rainfall variability and general atmospheric circulation indices for interannual and extreme event variability are moderately influenced by the El Niño-Southern Oscillation and Mediterranean Oscillation. Significant correlations are observed between the Southern Oscillation Index and annual rainfall in the northwestern part of the study area, which is likely linked with the decrease in rainfall in this region. Seasonal rainfall in Northern Algeria is affected by the Mediterranean Oscillation and North Atlantic Oscillation in the west. The ENSEMBLES regional climate models (RCMs) are assessed using the bias method to test their ability to reproduce rainfall variability at different time scales. The Centre National de Recherches Météorologiques (CNRM), Czech Hydrometeorological Institute (CHMI), Eidgenössische Technische Hochschule Zürich (ETHZ), and Forschungszentrum Geesthacht (GKSS) models yield the least biased results.

  7. Localization of beta and high-frequency oscillations within the subthalamic nucleus region.

    PubMed

    van Wijk, B C M; Pogosyan, A; Hariz, M I; Akram, H; Foltynie, T; Limousin, P; Horn, A; Ewert, S; Brown, P; Litvak, V

    2017-01-01

    Parkinsonian bradykinesia and rigidity are typically associated with excessive beta band oscillations in the subthalamic nucleus. Recently another spectral peak has been identified that might be implicated in the pathophysiology of the disease: high-frequency oscillations (HFO) within the 150-400 Hz range. Beta-HFO phase-amplitude coupling (PAC) has been found to correlate with severity of motor impairment. However, the neuronal origin of HFO and its usefulness as a potential target for deep brain stimulation remain to be established. For example, it is unclear whether HFO arise from the same neural populations as beta oscillations. We intraoperatively recorded local field potentials from the subthalamic nucleus while advancing DBS electrodes in 2 mm steps from 4 mm above the surgical target point until 2 mm below, resulting in 4 recording sites. Data from 26 nuclei from 14 patients were analysed. For each trajectory, we identified the recording site with the largest spectral peak in the beta range (13-30 Hz), and the largest peak in the HFO range separately. In addition, we identified the recording site with the largest beta-HFO PAC. Recording sites with largest beta power and largest HFO power coincided in 50% of cases. In the other 50%, HFO was more likely to be detected at a more superior recording site in the target area. PAC followed more closely the site with largest HFO (45%) than beta power (27%). HFO are likely to arise from spatially close, but slightly more superior neural populations than beta oscillations. Further work is necessary to determine whether the different activities can help fine-tune deep brain stimulation targeting.

  8. Oscillations in stellar atmospheres

    NASA Technical Reports Server (NTRS)

    Costa, A.; Ringuelet, A. E.; Fontenla, J. M.

    1989-01-01

    Atmospheric excitation and propagation of oscillations are analyzed for typical pulsating stars. The linear, plane-parallel approach for the pulsating atmosphere gives a local description of the phenomenon. From the local analysis of oscillations, the minimum frequencies are obtained for radially propagating waves. The comparison of the minimum frequencies obtained for a variety of stellar types is in good agreement with the observed periods of the oscillations. The role of the atmosphere in the globar stellar pulsations is thus emphasized.

  9. Spectral fingerprints of large-scale neuronal interactions.

    PubMed

    Siegel, Markus; Donner, Tobias H; Engel, Andreas K

    2012-01-11

    Cognition results from interactions among functionally specialized but widely distributed brain regions; however, neuroscience has so far largely focused on characterizing the function of individual brain regions and neurons therein. Here we discuss recent studies that have instead investigated the interactions between brain regions during cognitive processes by assessing correlations between neuronal oscillations in different regions of the primate cerebral cortex. These studies have opened a new window onto the large-scale circuit mechanisms underlying sensorimotor decision-making and top-down attention. We propose that frequency-specific neuronal correlations in large-scale cortical networks may be 'fingerprints' of canonical neuronal computations underlying cognitive processes.

  10. Oscillatory encoding of visual stimulus familiarity.

    PubMed

    Kissinger, Samuel T; Pak, Alexandr; Tang, Yu; Masmanidis, Sotiris C; Chubykin, Alexander A

    2018-06-18

    Familiarity of the environment changes the way we perceive and encode incoming information. However, the neural substrates underlying this phenomenon are poorly understood. Here we describe a new form of experience-dependent low frequency oscillations in the primary visual cortex (V1) of awake adult male mice. The oscillations emerged in visually evoked potentials (VEPs) and single-unit activity following repeated visual stimulation. The oscillations were sensitive to the spatial frequency content of a visual stimulus and required the muscarinic acetylcholine receptors (mAChRs) for their induction and expression. Finally, ongoing visually evoked theta (4-6 Hz) oscillations boost the VEP amplitude of incoming visual stimuli if the stimuli are presented at the high excitability phase of the oscillations. Our results demonstrate that an oscillatory code can be used to encode familiarity and serves as a gate for oncoming sensory inputs. Significance Statement. Previous experience can influence the processing of incoming sensory information by the brain and alter perception. However, the mechanistic understanding of how this process takes place is lacking. We have discovered that persistent low frequency oscillations in the primary visual cortex encode information about familiarity and the spatial frequency of the stimulus. These familiarity evoked oscillations influence neuronal responses to the oncoming stimuli in a way that depends on the oscillation phase. Our work demonstrates a new mechanism of visual stimulus feature detection and learning. Copyright © 2018 the authors.

  11. Radiation sensitivity of quartz crystal oscillators experiment for the Long Duration Exposure Facility (LDEF)

    NASA Technical Reports Server (NTRS)

    Ahearn, J. S.; Venables, J. D.

    1992-01-01

    Factors determining the radiation sensitivity of quartz crystal oscillators were studied on NASA's LDEF. Quartz materials were examined in the transmission electron microscope (TEM) and classified as to their sensitivity to radiation damage by establishing the rate of damage caused by the electron beam in the microscope. Two types of materials, i.e., swept premium Q quartz and natural quartz were chosen because clear differences were observed in their response to the electron beam in the TEM studies. Quartz resonators were then fabricated from them, tested for frequency stability over a greater than 6 mo. period and flown on the LDEF satellite. After retrieval (more than 7 yrs in space) the stability of the resonators was again determined. All of the space exposed resonators fabricated with swept premium Q material exhibited a frequency shift above that of the control resonators: none of the resonators fabricated from the natural quartz materials exhibited such a shift. The significant differences observed between the two types of materials in both the ground-based TEM studies and the space radiation induced frequency changes suggest that there may be a correlation between the two observations.

  12. Nonlinear Dynamics of Photonics for Optical Signal Processing - Optical Frequency Conversion and Optical DSB-to-SSB Conversion

    DTIC Science & Technology

    2015-09-17

    the literature, such as mode-locked lasers, optoelectronic oscillators , and laser optical heterodyne, our scheme is (1) up to 100 times better in... Optoelectronic oscillator : This scheme generates microwaves that are tunable only within a few gigahertz and that are stable with a linewidth down to 1 Hz... oscillation frequency, which can be easily adjusted by changing the power and frequency of the optical input. Tens to hundreds of GHz or even THz of

  13. A low power cryocooled autonomous ultra-stable oscillator

    NASA Astrophysics Data System (ADS)

    Fluhr, C.; Dubois, B.; Grop, S.; Paris, J.; Le Tetû, G.; Giordano, V.

    2016-12-01

    We present the design and the preliminary evaluation of a cryostat equipped with a low power pulse-tube cryocooler intended to maintain near 5 K a high-Q factor sapphire microwave resonator. This cooled resonator constitutes the frequency reference of an ultra-stable oscillator presenting a short term fractional frequency stability of better than 1 ×10-15 . The proposed design enables to reach a state-of-the-art frequency stability with a cryogenic oscillator consuming only 3 kW of electrical power.

  14. Frequency adjustment and synchrony in networks of delayed pulse-coupled oscillators

    NASA Astrophysics Data System (ADS)

    Nishimura, Joel

    2015-01-01

    We introduce a system of pulse-coupled oscillators that can change both their phases and frequencies and prove that when there is a separation of time scales between phase and frequency adjustment the system converges to exact synchrony on strongly connected graphs with time delays. The analysis involves decomposing the network into a forest of tree-like structures that capture causality. These results provide a robust method of sensor net synchronization as well as demonstrate a new avenue of possible pulse-coupled oscillator research.

  15. Wideband tunable 140 GHz second-harmonic InP-TED oscillator

    NASA Astrophysics Data System (ADS)

    Rydberg, A.; Kollberg, E.

    1986-07-01

    A second-harmonic InP-TED oscillator, with an output power of more than 3 dBm at 144 GHz and tunable over a 10 percent frequency range, has been developed. The design incorporates two waveguide resonators. One resonator determines the fundamental frequency of oscillation and the other optimizes the second-harmonic output power.

  16. Activation of D2 autoreceptors alters cocaine-induced locomotion and slows down local field oscillations in the rat ventral tegmental area.

    PubMed

    Koulchitsky, Stanislav; Delairesse, Charlotte; Beeken, Thom; Monteforte, Alexandre; Dethier, Julie; Quertemont, Etienne; Findeisen, Rolf; Bullinger, Eric; Seutin, Vincent

    2016-09-01

    Psychoactive substances affecting the dopaminergic system induce locomotor activation and, in high doses, stereotypies. Network mechanisms underlying the shift from an active goal-directed behavior to a "seemingly purposeless" stereotypic locomotion remain unclear. In the present study we sought to determine the relationships between the behavioral effects of dopaminergic drugs and their effects on local field potentials (LFPs), which were telemetrically recorded within the ventral tegmental area (VTA) of freely moving rats. We used the D2/D3 agonist quinpirole in a low, autoreceptor-selective (0.1 mg/kg, i.p.) and in a high (0.5 mg/kg, i.p.) dose, and a moderate dose of cocaine (10 mg/kg, i.p.). In the control group, power spectrum analysis revealed a prominent peak of LFP power in the theta frequency range during active exploration. Cocaine alone stimulated locomotion, but had no significant effect on the peak of the LFP power. In contrast, co-administration of low dose quinpirole with cocaine markedly altered the pattern of locomotion, from goal-directed exploratory behavior to recurrent motion resembling locomotor stereotypy. This behavioral effect was accompanied by a shift of the dominant theta power toward a significantly lower (by ∼15%) frequency. High dose quinpirole also provoked an increased locomotor activity with signs of behavioral stereotypies, and also induced a shift of the dominant oscillation frequency toward the lower range. These results demonstrate a correlation between the LFP oscillation frequency within the VTA and a qualitative aspect of locomotor behavior, perhaps due to a variable level of coherence of this region with its input or output areas. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Low Frequency (11 mHz) Oscillations in H1743-322: A New Class of Black Hole QPOs?

    NASA Technical Reports Server (NTRS)

    Altamirano, D.; Strohmayer, T.

    2012-01-01

    We report the discovery of quasi-periodic oscillations (QPO) at approx 11 mHz in two RXTE observations and one Chandra observation of the black hole candidate HI743-322. The QPO is observed only at the beginning of the 2010 and 2011 outbursts at similar hard color and intensity, suggestive of an accretion state dependence for the QPO. Although its frequency appears to be correlated with Xray intensity on timescales of a day, in successive outbursts eight months apart we measure a QPO frequency that differs by less than approximately equals 0.0015 Hz while the intensity had changed significantly. We show that this 11 mHz QPO is different from the so-called Type-C QPOs seen in black holes and that the mechanisms that produce the two flavors of variability are most probably independent. We compare the 11 mHz QPO with other variability phenomena seen in accreting black holes and neutron stars and conclude that although at 1-2 orders of magnitude lower in frequency, they best resemble the so-called "1 Hz" QPOs seen in dipping neutron star systems. If confirmed, H1743-322 is the first black hole showing this type of variability. Given the unusual characteristics and the hard-state dependence of the 11 mHz QPO, we speculate that these oscillations might instead be related to the radio jets observed in HI743-322. It remains unexplained, however, why similar QPOs have not yet been identified in other black holes and why they have only been seen in the last two outbursts of HI743-322.

  18. Amplitude mode oscillations in pump-probe photoemission spectra from a d -wave superconductor

    DOE PAGES

    Nosarzewski, B.; Moritz, B.; Freericks, J. K.; ...

    2017-11-20

    Recent developments in the techniques of ultrafast pump-probe photoemission have made possible the search for collective modes in strongly correlated systems out of equilibrium. Including inelastic scattering processes and a retarded interaction, we simulate time- and angle-resolved photoemission spectroscopy (trARPES) to study the amplitude mode of a d-wave superconductor, a collective mode excited through the nonlinear light-matter coupling to the pump pulse. We find that the amplitude mode oscillations of the d-wave order parameter occur in phase at a single frequency that is twice the quasi-steady-state maximum gap size after pumping. As a result, we comment on the necessary conditionsmore » for detecting the amplitude mode in trARPES experiments.« less

  19. Experimental transonic steady state and unsteady pressure measurements on a supercritical wing during flutter and forced discrete frequency oscillations

    NASA Technical Reports Server (NTRS)

    Piette, Douglas S.; Cazier, Frank W., Jr.

    1989-01-01

    Present flutter analysis methods do not accurately predict the flutter speeds in the transonic flow region for wings with supercritical airfoils. Aerodynamic programs using computational fluid dynamic (CFD) methods are being developed, but these programs need to be verified before they can be used with confidence. A wind tunnel test was performed to obtain all types of data necessary for correlating with CFD programs to validate them for use on high aspect ratio wings. The data include steady state and unsteady aerodynamic measurements on a nominal stiffness wing and a wing four times that stiffness. There is data during forced oscillations and during flutter at several angles of attack, Mach numbers, and tunnel densities.

  20. Amplitude mode oscillations in pump-probe photoemission spectra from a d -wave superconductor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nosarzewski, B.; Moritz, B.; Freericks, J. K.

    Recent developments in the techniques of ultrafast pump-probe photoemission have made possible the search for collective modes in strongly correlated systems out of equilibrium. Including inelastic scattering processes and a retarded interaction, we simulate time- and angle-resolved photoemission spectroscopy (trARPES) to study the amplitude mode of a d-wave superconductor, a collective mode excited through the nonlinear light-matter coupling to the pump pulse. We find that the amplitude mode oscillations of the d-wave order parameter occur in phase at a single frequency that is twice the quasi-steady-state maximum gap size after pumping. As a result, we comment on the necessary conditionsmore » for detecting the amplitude mode in trARPES experiments.« less

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