Parametric design analysis of a hybrid composite flywheel using a laminated central disc and a filament wound outer ring

NASA Astrophysics Data System (ADS)

Nimmer, R. P.

1980-09-01

A hybrid flywheel design concept based on the use of a laminated central disk with a filament-wound outer ring is analyzed for several different combinations of composite materials. Some of the results of this study are: (1) an optimized E-glass disk with Kevlar-49 outer ring offers the prospect of 30% additional energy density over a laminated disk without a ring; (2) a laminated S2-glass disk is capable of storing more energy per unit mass than an E-glass disk because of its higher tensile strength; and (3) the use of wound graphite outer rings with S2-glass disks leads to substantial reductions in the size of the interference fit while offering still higher energy densities than for a Kevlar-49 outer ring.

Atmospheric entry probes for outer planet exploration. Outer planet entry probe technical summary

NASA Technical Reports Server (NTRS)

1974-01-01

The use of unmanned space probes for investigating the conditions existing on and around the outer planets of the solar system is discussed. The subjects included in the report are: (1) the design of a common entry probe for outer planet missions, (2) the significant trades related to the development of a common probe design, (3) the impact of bus selection on probe design, (4) the impact of probe requirements on bus modifications, and (5) the key technology elements recommended for advanced development. Drawings and illustrations of typical probes are included to show the components and systems used in the space probes.

Research on a 170 GHz, 2 MW coaxial cavity gyrotron with inner-outer corrugation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hou, Shenyong, E-mail: houshenyong@sohu.com; Yu, Sheng; Li, Hongfu

2015-03-15

In this paper, a coaxial cavity gyrotron with inner-outer corrugation is researched. The electron kineto-equations and the first order transmission line equations of the gyrotron are derived from Lorentz force equation and the transmission line theory, respectively. And then, a 2 MW, 170 GHz coaxial cavity gyrotron with inner-outer corrugation is designed. By means of numerical calculation, the beam-wave interaction of the coaxial cavity gyrotron with inner-outer corrugation is investigated. Results show that the efficient and the outpower of the gyrotron are 42.3% and 2.38 MW, respectively.

The Properties of Outer Retinal Band Three Investigated With Adaptive-Optics Optical Coherence Tomography.

PubMed

Jonnal, Ravi S; Gorczynska, Iwona; Migacz, Justin V; Azimipour, Mehdi; Zawadzki, Robert J; Werner, John S

2017-09-01

Optical coherence tomography's (OCT) third outer retinal band has been attributed to the zone of interdigitation between RPE cells and cone outer segments. The purpose of this paper is to investigate the structure of this band with adaptive optics (AO)-OCT. Using AO-OCT, images were obtained from two subjects. Axial structure was characterized by measuring band 3 thickness and separation between bands 2 and 3 in segmented cones. Lateral structure was characterized by correlation of band 3 with band 2 and comparison of their power spectra. Band thickness and separation were also measured in a clinical OCT image of one subject. Band 3 thickness ranged from 4.3 to 6.4 μm. Band 2 correlations ranged between 0.35 and 0.41 and power spectra of both bands confirmed peak frequencies that agree with histologic density measurements. In clinical images, band 3 thickness was between 14 and 19 μm. Measurements of AO-OCT of interband distance were lower than our corresponding clinical OCT measurements. Band 3 originates from a structure with axial extent similar to a single surface. Correlation with band 2 suggests an origin within the cone photoreceptor. These two observations indicate that band 3 corresponds predominantly to cone outer segment tips (COST). Conventional OCT may overestimate both the thickness of band 3 and outer segment length.

The Properties of Outer Retinal Band Three Investigated With Adaptive-Optics Optical Coherence Tomography

PubMed Central

Jonnal, Ravi S.; Gorczynska, Iwona; Migacz, Justin V.; Azimipour, Mehdi; Zawadzki, Robert J.; Werner, John S.

2017-01-01

Purpose Optical coherence tomography's (OCT) third outer retinal band has been attributed to the zone of interdigitation between RPE cells and cone outer segments. The purpose of this paper is to investigate the structure of this band with adaptive optics (AO)-OCT. Methods Using AO-OCT, images were obtained from two subjects. Axial structure was characterized by measuring band 3 thickness and separation between bands 2 and 3 in segmented cones. Lateral structure was characterized by correlation of band 3 with band 2 and comparison of their power spectra. Band thickness and separation were also measured in a clinical OCT image of one subject. Results Band 3 thickness ranged from 4.3 to 6.4 μm. Band 2 correlations ranged between 0.35 and 0.41 and power spectra of both bands confirmed peak frequencies that agree with histologic density measurements. In clinical images, band 3 thickness was between 14 and 19 μm. Measurements of AO-OCT of interband distance were lower than our corresponding clinical OCT measurements. Conclusions Band 3 originates from a structure with axial extent similar to a single surface. Correlation with band 2 suggests an origin within the cone photoreceptor. These two observations indicate that band 3 corresponds predominantly to cone outer segment tips (COST). Conventional OCT may overestimate both the thickness of band 3 and outer segment length. PMID:28877320

Positive contact, self retaining bearing seals

DOEpatents

Johnson, Bruce H.; Larsen, Lawrence E.; Welch, Edmund F.

1992-05-05

An ultra-low friction bearing including an inner race, an outer race, bearing elements engaged between the inner and outer races and a seal between the inner and outer races is disclosed. The seal includes first and second sealing washers. The first washer has an outer diameter greater than an inner diameter of the outer race and an inner diameter greater than the outer diameter of the inner race. The second washer has an inner diameter less than the outer diameter of the inner race and an outer diameter less than the inner diameter of the outer race. The first washer slidably engages the outer race, the second washer slidably engages the inner race and the washers overlap and slidably engage one another. One of the washers snap fits into its respective inner or outer race while the other washer engages a stepped surface of the other of the inner and outer races. The grooved and stepped surface are offset from one another in a longitudinal direction of the races such that the washers are conically loaded thus providing a seal between the inner and outer races sufficient to prevent lubricant and contaminating particles from passing therethrough. The washers are made from a non-metallic semi-flexible low-modulus material.

Activities conducted during the definition phase of the outer planets missions program

NASA Technical Reports Server (NTRS)

1972-01-01

The activities are described of the Meteoroid Science Team for the definition phase of the outer planet missions. Studies reported include: (1) combined zodiacal experiment for the Grand Tour Missions of the outer planets, (2) optical transmission of a honeycomb panel and its effectiveness as a particle impact surface, (3) element identification data from the combined zodiacal OPGT experiment and (4) development of lightweight thermally stable mirrors.

Component with inspection-facilitating features

DOEpatents

Marra, John J; Zombo, Paul J

2014-02-11

A turbine airfoil can be formed with features to facilitate measurement of its wall thickness. An outer wall of the airfoil can include an outer surface and an inner surface. The outer surface of the airfoil can have an outer inspection target surface, and the inner surface of the airfoil can have an inner inspection target surface. The inner and outer target surfaces can define substantially flat regions in surfaces that are otherwise highly contoured. The inner and outer inspection target surfaces can be substantially aligned with each other. The inner and outer target surfaces can be substantially parallel to each other. As a result of these arrangements, a highly accurate measurement of wall thickness can be obtained. In one embodiment, the outer inspection target surface can be defined by an innermost surface of a groove formed in the outer surface of the outer wall of the airfoil.

Characterization of polymer chain fractions of kiwifruit starch.

PubMed

Li, Dongxing; Zhu, Fan

2018-02-01

In this report, the amylose composition and molecular structure of starches from the core and outer pericarp of 3 golden kiwifruit varieties were characterised, using enzymatic and chromatographic techniques. Starches from the core tissues of kiwifruit tend to have higher amylose contents (by ∼3-5%) and longer unit chains of both amylopectins and their φ, β-limit dextrins (LDs) than those of the outer pericarp starches. The contents of short B-chains of the φ, β-LDs of amylopectins from the outer pericarp were higher (by ∼3%) than those of φ, β-LDs of the core amylopectins. Overall, the composition and structure of starches from the outer pericarp and core tissues of a golden kiwifruit were different. This study provides a structural basis to further investigate the starch degradation in kiwifruit, which may be of importance for the storage and eating quality of the fruit. Copyright © 2017 Elsevier Ltd. All rights reserved.

Star Formation Activity Beyond the Outer Arm. I. WISE -selected Candidate Star-forming Regions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Izumi, Natsuko; Yasui, Chikako; Saito, Masao

The outer Galaxy beyond the Outer Arm provides a good opportunity to study star formation in an environment significantly different from that in the solar neighborhood. However, star-forming regions in the outer Galaxy have never been comprehensively studied or cataloged because of the difficulties in detecting them at such large distances. We studied 33 known young star-forming regions associated with 13 molecular clouds at R {sub G} ≥ 13.5 kpc in the outer Galaxy with data from the Wide-field Infrared Survey Explorer ( WISE ) mid-infrared all-sky survey. From their color distribution, we developed a simple identification criterion of star-forming regions inmore » the outer Galaxy with the WISE color. We applied the criterion to all the WISE sources in the molecular clouds in the outer Galaxy at R {sub G} ≥ 13.5 kpc detected with the Five College Radio Astronomy Observatory (FCRAO) {sup 12}CO survey of the outer Galaxy, of which the survey region is 102.°49 ≤  l  ≤ 141.°54, −3.°03 ≤  b  ≤ 5.°41, and successfully identified 711 new candidate star-forming regions in 240 molecular clouds. The large number of samples enables us to perform the statistical study of star formation properties in the outer Galaxy for the first time. This study is crucial to investigate the fundamental star formation properties, including star formation rate, star formation efficiency, and initial mass function, in a primordial environment such as the early phase of the Galaxy formation.« less

Relationship between macular ganglion cell complex thickness and macular outer retinal thickness: a spectral-domain optical coherence tomography study.

PubMed

Kita, Yoshiyuki; Kita, Ritsuko; Takeyama, Asuka; Anraku, Ayako; Tomita, Goji; Goldberg, Ivan

2013-01-01

To assess the relationship between macular ganglion cell complex and macular outer retinal thicknesses. Case-control study. Forty-two normal eyes and 91 eyes with primary open-angle glaucoma were studied. Spectral-domain optical coherence tomography (RTVue-100) was used to measure the macular ganglion cell complex and macular outer retinal thickness. Ganglion cell complex to outer retinal thickness ratio was also calculated. The relationships between the ganglion cell complex and outer retinal thicknesses and between the ganglion cell complex to outer retinal thickness ratio and outer retinal thickness were evaluated. There was a positive correlation between ganglion cell complex and outer retinal thicknesses in the normal group and the glaucoma group (r = 0.53, P < 0.001 and r = 0.42, P < 0.001, respectively). In that respect, there was no correlation between ganglion cell complex to outer retinal thickness ratio and outer retinal thickness in the both groups (r = -0.07, P = 0.657, and r = 0.04, P = 0.677, respectively). The ganglion cell complex to outer retinal thickness ratio was 55.65% in the normal group, 45.07% in the glaucoma group. This difference was statistically significant. The ganglion cell complex thickness may be affected by outer retinal thickness, and there is individual variation in the outer retinal thickness. Therefore, when determining the ganglion cell complex, it seems necessary to consider the outer retinal thickness as well. We propose the ratio as a suitable parameter to account for individual variations in outer retinal thickness. © 2013 The Authors. Clinical and Experimental Ophthalmology © 2013 Royal Australian and New Zealand College of Ophthalmologists.

The Leptospira outer membrane protein LipL32 induces tubulointerstitial nephritis-mediated gene expression in mouse proximal tubule cells.

PubMed

Yang, Chih-Wei; Wu, Mai-Szu; Pan, Ming-Jeng; Hsieh, Wang-Ju; Vandewalle, Alain; Huang, Chiu-Ching

2002-08-01

Tubulointerstitial nephritis is a main renal manifestation caused by pathogenic leptospira that accumulate mostly in the proximal tubules, thereby inducing tubular injury and tubulointerstitial nephritis. To elucidate the role of leptospira outer membrane proteins in tubulointerstitial nephritis, outer membrane proteins from pathogenic Leptospira shermani and nonpathogenic Leptospira patoc extracted by Triton X-114 were administered to cultured mouse proximal tubule cells. A dose-dependent increase of monocyte chemoattractant protein-1 (MCP-1), RANTES, nitrite, and tumor necrosis factor-alpha (TNF-alpha) in the culture supernatant was observed 48 h after incubating Leptospira shermani outer membrane proteins with mouse proximal tubule cells. RT competitive-PCR experiments showed that Leptospira shermani outer membrane proteins (0.2 microg/ml) increased the expression of MCP-1, nitric oxide synthase (iNOS), RANTES, and TNF-alpha mRNA by 3.0-, 9.4-, 2.5-, and 2.5-fold, respectively, when compared with untreated cells. Outer membrane proteins extract from avirulent Leptospira patoc did not induce significant effects. The pathogenic outer membrane proteins extract contain a major component of a 32-kD lipoprotein (LipL32), which is absent in the nonpathogenic leptospira outer membrane. An antibody raised against LipL32 prevented the stimulatory effect of Leptospira shermani outer membrane proteins extract on MCP-1 and iNOS mRNA expression in cultured proximal tubule cells, whereas recombinant LipL32 significantly stimulated the expression of MCP-1 and iNOS mRNAs and augmented nuclear binding of nuclear factor-kappaB (NF-kappaB) and AP-1 transcription factors in proximal tubule cells. An antibody raised against LipL32 also blunted the effects induced by the recombinant LipL32. This study demonstrates that LipL32 is a major component of pathogenic leptospira outer membrane proteins involved in the pathogenesis of tubulointerstitial nephritis.

Double-ended metal halide arc discharge lamp with electrically isolated containment shroud

NASA Technical Reports Server (NTRS)

Muzeroll, Martin M. (Inventor)

1994-01-01

A double-ended arc discharge lamp includes a sealed, light-transmissive outer jacket, a light-transmissive shroud mounted within the outer jacket and directly supported by the outer jacket, and an arc discharge tube mounted within the shroud. The arc tube is typically a metal halide arc discharge tube. In a preferred embodiment, the shroud includes an outwardly flared portion at each end. The outwardly flared portions space the shroud from the outer jacket and support the shroud within the outer jacket. The outwardly flared portions of the shroud can be affixed to the outer jacket by fusing. The outer jacket can be provided with inwardly extending dimples for locating the shroud with respect to the outer jacket. In another embodiment, the outer jacket includes reduced diameter portions near each end which are attached to the shroud.

Asymmetric Outer Bow Length and Cervical Headgear Force System: 3D Analysis Using Finite Element Method

PubMed Central

Geramy, Allahyar; Hassanpour, Mehdi; Emadian Razavi, Elham sadat

2015-01-01

Objectives: This study sought to assess distal and lateral forces and moments of asymmetric headgears by variable outer bow lengths. Materials and Methods: Four 3D finite element method (FEM) models of a cervical headgear attached to the maxillary first molars were designed in SolidWorks 2010 software and transferred to ANSYS Workbench ver. 11 software. Models contained the first molars, their periodontal ligament (PDL), cancellous and cortical bones, a mesiodistal slice of the maxillae and the headgear. Models were the same except for the outer bow length in headgears. The headgear was symmetric in model 1. In models 2 to 4, the headgears were asymmetric in length with differences of 5mm, 10mm and 15mm, respectively. A 2.5 N force in horizontal plane was applied and the loading manner of each side of the outer bow was calculated trigonometrically using data from a volunteer. Results: The 15mm difference in outer bow length caused the greatest difference in lateral (=0.21 N) and distal (= 1.008 N) forces and also generated moments (5.044 N.mm). Conclusion: As the difference in outer bow length became greater, asymmetric effects increased. Greater distal force in the longer arm side was associated with greater lateral force towards the shorter arm side and more net yawing moment. Clinical Relevance: A difference range of 1mm to 15 mm of length in cervical headgear can be considered as a safe length of outer bow shortening in clinical use. PMID:26622275

Atmospheric Mining in the Outer Solar System:. [Aerial Vehicle Reconnaissance and Exploration Options

NASA Technical Reports Server (NTRS)

Palaszewski, Bryan A.

2014-01-01

Atmospheric mining in the outer solar system has been investigated as a means of fuel production for high energy propulsion and power. Fusion fuels such as Helium 3 (3He) and hydrogen can be wrested from the atmospheres of Uranus and Neptune and either returned to Earth or used in-situ for energy production. Helium 3 and hydrogen (deuterium, etc.) were the primary gases of interest with hydrogen being the primary propellant for nuclear thermal solid core and gas core rocket-based atmospheric flight. A series of analyses were undertaken to investigate resource capturing aspects of atmospheric mining in the outer solar system. This included the gas capturing rate, storage options, and different methods of direct use of the captured gases. Additional supporting analyses were conducted to illuminate vehicle sizing and orbital transportation issues. While capturing 3He, large amounts of hydrogen and 4He are produced. With these two additional gases, the potential for fueling small and large fleets of additional exploration and exploitation vehicles exists. Additional aerospacecraft or other aerial vehicles (UAVs, balloons, rockets, etc.) could fly through the outer planet atmospheres, for global weather observations, localized storm or other disturbance investigations, wind speed measurements, polar observations, etc. Deep-diving aircraft (built with the strength to withstand many atmospheres of pressure) powered by the excess hydrogen or helium 4 may be designed to probe the higher density regions of the gas giants. Outer planet atmospheric properties, atmospheric storm data, and mission planning for future outer planet UAVs are presented.

A comparative study on component volumes from outer to inner dental enamel in relation to enamel tufts.

PubMed

Setally Azevedo Macena, Marcus; de Alencar e Silva Leite, Maria Luísa; de Lima Gouveia, Cíntia; de Lima, Tamires Alcoforado Sena; Athayde, Priscilla Alves Aguiar; de Sousa, Frederico Barbosa

2014-06-01

Dental enamel presents marked mechanical properties gradients from outer to inner enamel, a region lacking component volumes profiles. Tufts, structures of inner enamel, have been shown to play a role in enamel resilience. We aimed at comparing component volumes from inner to outer enamel in relation to enamel tufts. Transversal ground sections from the cervical half of unerupted human third molars (n=10) were prepared and histological points were selected along transversal lines (extending from innermost to outer enamel) traced across tufts and adjacent control areas without tufts. Component volumes were measured at each histological point. Component volumes ranges were: 70.6-98.5% (mineral), 0.02-20.78% (organic), 3.8-9.8% (total water), 3-9% (firmly bound water), and 0.02-3.3% (loosely bound water). Inner enamel presented the lowest mineral volumes and the highest non-mineral volumes. Mineral, water and organic contents differed as a function of the distance from innermost enamel but not between the tuft and control lines. Tufts presented opaqueness in polarizing microscopy (feature of fracture lines). Organic volume gradient correlated with a relatively flat profile of loosely bound water. Inner, but not outer enamel, rehydrated after air-dried enamel was heated to 50°C and re-exposed to room conditions, as predicted by the organic/water gradient profiles. Component volumes vary markedly from outer to inner enamel, but not between areas with or without tufts (that behave like fracture lines under polarizing microscopy). Copyright © 2014 Elsevier Ltd. All rights reserved.

27 CFR 9.207 - Outer Coastal Plain.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Outer Coastal Plain. (a) Name. The name of the viticultural area described in this section is “Outer...,000 scale. (c) Boundary. The Outer Coastal Plain viticultural area includes all of Cumberland, Cape... Counties in the State of New Jersey. The boundary of the Outer Coastal Plain viticultural area is as...

Cooled turbine vane with endcaps

DOEpatents

Cunha, Frank J.; Schiavo, Jr., Anthony L.; Nordlund, Raymond Scott; Malow, Thomas; McKinley, Barry L.

2002-01-01

A turbine vane assembly which includes an outer endcap having a plurality of generally straight passages and passage segments therethrough, an inner endcap having a plurality of passages and passage segments therethrough, and a vane assembly having an outer shroud, an airfoil body, and an inner shroud. The outer shroud, airfoil body and inner shroud each have a plurality of generally straight passages and passage segments therethrough as well. The outer endcap is coupled to the outer shroud so that outer endcap passages and said outer shroud passages form a fluid circuit. The inner endcap is coupled to the inner shroud so that the inner end cap passages and the inner shroud passages from a fluid circuit. Passages in the vane casting are in fluid communication with both the outer shroud passages and the inner shroud passages. Passages in the outer endcap may be coupled to a cooling system that supplies a coolant and takes away the heated exhaust.

Stellar populations, stellar masses and the formation of galaxy bulges and discs at z < 3 in CANDELS

NASA Astrophysics Data System (ADS)

Margalef-Bentabol, Berta; Conselice, Christopher J.; Mortlock, Alice; Hartley, Will; Duncan, Kenneth; Kennedy, Rebecca; Kocevski, Dale D.; Hasinger, Guenther

2018-02-01

We present a multicomponent structural analysis of the internal structure of 1074 high-redshift massive galaxies at 1 < z < 3 from the CANDELS HST Survey. In particular, we examine galaxies best fitted by two structural components, and thus likely forming discs and bulges. We examine the stellar mass, star formation rates (SFRs) and colours of both the inner 'bulge' and outer 'disc' components for these systems using Spectral Energy Distribution (SED) information from the resolved ACS+WFC3 HST imaging. We find that the majority of both inner and outer components lie in the star-forming region of UVJ space (68 and 90 per cent, respectively). However, the inner portions, or the likely forming bulges, are dominated by dusty star formation. Furthermore, we show that the outer components of these systems have a higher SFR than their inner regions, and the ratio of SFR between 'disc' and 'bulge' increases at lower redshifts. Despite the higher SFR of the outer component, the stellar mass ratio of inner to outer component remains constant through this epoch. This suggests that there is mass transfer from the outer to inner components for typical two-component-forming systems, thus building bulges from discs. Finally, using Chandra data we find that the presence of an active galactic nucleus is more common in both one-component spheroid-like galaxies and two-component systems (13 ± 3 and 11 ± 2 per cent) than in one-component disc-like galaxies (3 ± 1 per cent), demonstrating that the formation of a central inner component likely triggers the formation of central massive black holes in these galaxies.

Unilateral Outer Bow Expanded Cervical Headgear Force System: 3D Analysis Using Finite Element Method.

PubMed

Geramy, Allahyar; Mortezai, Omid; Esmaily, Masomeh; Darvishpour, Hojat

2015-04-01

Headgears are among the effective orthodontic appliances to achieve treatment goals. Unilateral molar distal movement is sometimes needed during an orthodontic treatment, which can be achieved by an asymmetric headgear. Different unilateral headgears have been introduced. The main goal of this study was to analyze the force system of unilateral expanded outer bow asymmetric headgears by the finite element method (FEM). Six 3D finite element models of a mesiodistal slice of the maxilla containing upper first molars, their periodontal ligaments (PDLs), cancellous bone, cortical bone, and a cervical headgear with expanded outer bow attached to maxillary first molars were designed in SolidWorks 2010 and meshed in ANSYS Workbench ver. 12.1. The models were the same except for the degree of outer bow expansion. The outer bow ends were loaded with 2 N force. The distal driving force and the net moment were evaluated. A decrease in the distalizing force in the normal side molar from 1.69 N to 1.37 N was shown by increasing the degree of unilateral expansion. At the same time, the force increased from 2.19 N to 2.49 N in the expanded side molar. A net moment increasing from 2.26 N.mm to 4.64 N.mm was also shown. Unilateral outer bow expansion can produce different distalizing forces in molars, which increase by increasing the expansion.

Autofluorescence from the outer retina and subretinal space: hypothesis and review.

PubMed

Spaide, Richard

2008-01-01

To review the pathophysiologic principles underlying increased autofluorescence from the outer retina and subretinal space using selected diseases as examples. The ocular imaging information and histopathologic features, when known, were integrated for diseases causing increased autofluorescence from the outer retina and subretinal space. Inferences were taken from this information and used to create a classification scheme. These diseases are principally those that cause separation of the outer retina from the retinal pigment epithelium, thereby preventing proper phagocytosis of photoreceptor outer segments. The separation can arise from increased exudation into the subretinal space or inadequate removal of fluid from the subretinal space. Lack of normal outer segment processing initially leads to increased accumulation of outer segments on the outer retina and subretinal space. Over time, this material is visible as an increasingly thick coating on the outer retina, is yellow, and is autofluorescent. Over time, atrophy develops with thinning of the deposited material and decreasing autofluorescence. The accumulated material is ultimately capable of inducing damage to the retinal pigment epithelium. Diseases causing accumulation of the material include central serous chorioretinopathy, vitelliform macular dystrophy, acute exudative polymorphous vitelliform maculopathy, choroidal tumors, and vitreomacular traction syndrome. The physical separation of the retinal outer segments from the retinal pigment epithelium hinders proper phagocytosis of the outer segments. Accumulation of the shed but not phagocytized outer segments plays a role in disease manifestations for a number of macular diseases.

Review of the outer scale of the atmospheric turbulence

NASA Astrophysics Data System (ADS)

Ziad, Aziz

2016-07-01

Outer scale is a relevant parameter for the experimental performance evaluation of large telescopes. Different techniques have been used for the outer scale estimation. In situ measurements with radiosounding balloons have given very small values of outer scale. This latter has also been estimated directly at the ground level from the wavefront analysis with High Angular Resolution (HAR) techniques using interferometric or Shack-Hartmann or more generally AO systems data. Dedicated instruments have been also developed for the outer scale monitoring such as the Generalized Seeing Monitor (GSM) and the Monitor of Outer Scale Profile (MOSP). The measured values of outer scale from HAR techniques, GSM and MOSP are somewhat coherent and are larger than the in situ results. The main explanation of this difference comes from the definition of the outer scale itself. This paper aims to give a review in a non-exhaustive way of different techniques and instruments for the measurement of the outer scale. Comparisons of outer scale measurements will be discussed in the light of the different definitions of this parameter, the associated observable quantities and the atmospheric turbulence model as well.

THE M33 GLOBULAR CLUSTER SYSTEM WITH PAndAS DATA: THE LAST OUTER HALO CLUSTER?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cockcroft, Robert; Harris, William E.; Ferguson, Annette M. N., E-mail: cockcroft@physics.mcmaster.ca, E-mail: harris@physics.mcmaster.ca, E-mail: ferguson@roe.ac.uk

2011-04-01

We use CFHT/MegaCam data to search for outer halo star clusters in M33 as part of the Pan-Andromeda Archaeological Survey. This work extends previous studies out to a projected radius of 50 kpc and covers over 40 deg{sup 2}. We find only one new unambiguous star cluster in addition to the five previously known in the M33 outer halo (10 kpc {<=} r {<=} 50 kpc). Although we identify 2440 cluster candidates of various degrees of confidence from our objective image search procedure, almost all of these are likely background contaminants, mostly faint unresolved galaxies. We measure the luminosity, color,more » and structural parameters of the new cluster in addition to the five previously known outer halo clusters. At a projected radius of 22 kpc, the new cluster is slightly smaller, fainter, and redder than all but one of the other outer halo clusters, and has g' {approx} 19.9, (g' - i') {approx} 0.6, concentration parameter c {approx} 1.0, a core radius r{sub c} {approx} 3.5 pc, and a half-light radius r{sub h} {approx} 5.5 pc. For M33 to have so few outer halo clusters compared to M31 suggests either tidal stripping of M33's outer halo clusters by M31, or a very different, much calmer accretion history of M33.« less

The M33 Globular Cluster System with PAndAS Data: the Last Outer Halo Cluster?

NASA Astrophysics Data System (ADS)

Cockcroft, Robert; Harris, William E.; Ferguson, Annette M. N.; Huxor, Avon; Ibata, Rodrigo; Irwin, Mike J.; McConnachie, Alan W.; Woodley, Kristin A.; Chapman, Scott C.; Lewis, Geraint F.; Puzia, Thomas H.

2011-04-01

We use CFHT/MegaCam data to search for outer halo star clusters in M33 as part of the Pan-Andromeda Archaeological Survey. This work extends previous studies out to a projected radius of 50 kpc and covers over 40 deg2. We find only one new unambiguous star cluster in addition to the five previously known in the M33 outer halo (10 kpc <= r <= 50 kpc). Although we identify 2440 cluster candidates of various degrees of confidence from our objective image search procedure, almost all of these are likely background contaminants, mostly faint unresolved galaxies. We measure the luminosity, color, and structural parameters of the new cluster in addition to the five previously known outer halo clusters. At a projected radius of 22 kpc, the new cluster is slightly smaller, fainter, and redder than all but one of the other outer halo clusters, and has g' ≈ 19.9, (g' - i') ≈ 0.6, concentration parameter c ≈ 1.0, a core radius rc ≈ 3.5 pc, and a half-light radius rh ≈ 5.5 pc. For M33 to have so few outer halo clusters compared to M31 suggests either tidal stripping of M33's outer halo clusters by M31, or a very different, much calmer accretion history of M33.

Turbine exhaust diffuser with region of reduced flow area and outer boundary gas flow

DOEpatents

Orosa, John

2014-03-11

An exhaust diffuser system and method for a turbine engine. The outer boundary may include a region in which the outer boundary extends radially inwardly toward the hub structure and may direct at least a portion of an exhaust flow in the diffuser toward the hub structure. At least one gas jet is provided including a jet exit located on the outer boundary. The jet exit may discharge a flow of gas downstream substantially parallel to an inner surface of the outer boundary to direct a portion of the exhaust flow in the diffuser toward the outer boundary to effect a radially outward flow of at least a portion of the exhaust gas flow toward the outer boundary to balance an aerodynamic load between the outer and inner boundaries.

Action of sympathetic nerves of inner and outer muscle of sheep carotid artery, and effect of pressure on nerve distribution.

PubMed Central

Keatinge, W R; Torrie, C

1976-01-01

1. The direction of torsion produced during active shortening of helical strips of sheep carotid arteries was measured to assess whether inner or outer muscle was contracting. 2. Noradrenaline contracted inner (non-innervated) muscle in lower concentrations than were needed to contract outer (innervated) muscle, even with desipramine present to prevent uptake of noradrenaline by the nerves and with enough cyanide present to rise the normally low O2 tension of inner muscle to that of outer muscle. 3. Activation of sympathetic nerves in the outer part of the artery by nicotine caused almost evenly balanced contraction of both parts of the wall, with slight bias to outer contraction. 4. Moderate external constriction of the artery in vivo for 10-17 days, in order to raise pressure throughout the wall to intraluminal pressure, made the entire wall nerve-free. 5. The results provide evidence that the nerves can induce substantial activation of inner muscle, which is highly sensitive to noradrenaline, and that the absence of nerves from inner muscle can be explained by the high pressure there. Images Plate 1 PMID:950610

75 FR 1076 - Outer Continental Shelf Civil Penalties

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-08

...The Outer Continental Shelf Lands Act requires the MMS to review the maximum daily civil penalty assessment for violations of regulations governing oil and gas operations in the Outer Continental Shelf at least once every 3 years. This review ensures that the maximum penalty assessment reflects any increases in the Consumer Price Index as prepared by the Bureau of Labor Statistics, U.S. Department of Labor. After conducting the required review in August 2009, the MMS determined that no adjustment is necessary at this time.

Quality improvement of laminated board made from oil palm trunk at various outer layer using phenol formaldehyde adhesive

NASA Astrophysics Data System (ADS)

Hartono, R.; Sucipto, T.

2018-02-01

Characteristic of laminated board from oil palm trunk (OPT) is very low in quality. The effort to improved it’s quality done by using the outer layer from high density wood. The purpose of this experiment was to analyzed the effects of the outer layer on physical and mechanical properties of OPT and to obtain optimum treatment to fulfills JAS 234:2003. All of laminated board was made of 3 layers, and for the middle layer was made by densified-OPT. Then for the outer layer was made of sengon and meranti wood. The sample size was 5 cm (width) × 3 cm (thick) × 45 cm (length). The various outer layer of laminated board were A (OPT/densified OPT/OPT); B (Sengon/densified OPT/OPT); C (Sengon/densified OPT/sengon); D (Meranti/densified OPT/OPT) and E (Meranti/densified OPT/meranti). The results showed that the moisture content, density, thickness swelling, delamination, MOR and MOE were 6.10-8.48%; 0.40-0.63 g/cm3; 6.43-13.20%; 0%; 168.79-438.29 kg/cm2 and 30115-100454 kg/cm2, respectively. The moisture content and delamination fulfills JAS 234:2003, while density and thickness swelling did not fulfill standard. Whereas for MOR and MOE value, only type D and E that fulfill standard. There are strongth relationship between density and mechanical properties, such as MOR and MOE value. The optimum treatment in this reseach to made laminated board made from OPT was type D that using the meranti as outer layer.

Magnetic circuit for hall effect plasma accelerator

NASA Technical Reports Server (NTRS)

Manzella, David H. (Inventor); Jacobson, David T. (Inventor); Hofer, Richard (Inventor); Peterson, Peter (Inventor); Jankovsky, Robert S. (Inventor)

2009-01-01

A Hall effect plasma accelerator includes inner and outer electromagnets, circumferentially surrounding the inner electromagnet along a thruster centerline axis and separated therefrom, inner and outer magnetic conductors, in physical connection with their respective inner and outer electromagnets, with the inner magnetic conductor having a mostly circular shape and the outer magnetic conductor having a mostly annular shape, a discharge chamber, located between the inner and outer magnetic conductors, a magnetically conducting back plate, in magnetic contact with the inner and outer magnetic conductors, and a combined anode electrode/gaseous propellant distributor, located at a bottom portion of the discharge chamber. The inner and outer electromagnets, the inner and outer magnetic conductors and the magnetically conducting back plate form a magnetic circuit that produces a magnetic field that is largely axial and radially symmetric with respect to the thruster centerline.

Evaluation of inner-outer space distinction and verbal hallucinations in schizophrenia.

PubMed

Stephane, Massoud; Kuskowski, Michael; McClannahan, Kate; Surerus, Christa; Nelson, Katie

2010-09-01

Verbal hallucinations could result from attributing one's own inner speech to another. Inner speech is usually experienced in inner space, whereas hallucinations are often experienced in outer space. To clarify this paradox, we investigated schizophrenia patients' ability to distinguish between speech experienced in inner space, and speech experienced in outer space. 32 schizophrenia patients and 26 matched healthy controls underwent a two-stage experiment. First, they read sentences aloud or silently. Afterwards, they were required to distinguish between the sentences read aloud (experienced in outer space), the sentences read silently (experienced in inner space), and new sentences not previously read (no space coding). The sentences were in the first, second, or third person in equal proportions. Linear mixed models were used to investigate the effects of group, sentence location, pronoun, and hallucinations status. Schizophrenia patients were similar to controls in recognition capacity of sentences without space coding. They exhibited both inner-outer and outer-inner space confusion (they confused silently read sentences for sentences read aloud, and vice versa). Patients who experienced hallucinations inside their head were more likely to have outer-inner space bias. For speech generated by one's own brain, schizophrenia patients have bidirectional failure of inner-outer space distinction (inner-outer and outer-inner space biases); this might explain why hallucinations (abnormal inner speech) could be experienced in outer space. Furthermore, the direction of inner-outer space indistinction could determine the spatial location of the experienced hallucinations (inside or outside the head).

Plasmas in the outer heliosphere

NASA Technical Reports Server (NTRS)

Belcher, J. W.; Richardson, J. D.; Lazarus, A. J.; Gazis, P. R.; Barnes, A.

1995-01-01

We review the observed properties of the solar wind in the outer heliosphere, including observations from Voyager and the Pioneers, as well as from inner heliospheric probes as appropriate. These observations are crucial to modeling of the heliosphere and its interactions with the interstellar medium, since the wind ram pressure and its temporal variations are important in understanding the distance to the termination shock and heliopause and how those boundaries might vary in time. We focus on results since Solar Wind 7. Among the issues we will discuss are: (1) the time scales for and statistical properties of variations in the ram pressure in the outer heliosphere, and how those variations might affect the morphology of the heliospheric/interstellar medium interface; (2) the question of possible solar wind slowing in the outer heliosphere due to the pick-up of interstellar ions; (3) the issue of whether there is bulk heating of the solar wind associated either with interstellar ion pick-up or with continued heating due to stream-stream interactions; (4) evidence for latitudinal variations in solar wind properties; and (5) the 1.3 year periodicities apparent in the outer heliosphere, and the close correspondence with similar variations seen with inner heliospheric probes.

Physicochemical properties of kiwifruit starch.

PubMed

Li, Dongxing; Zhu, Fan

2017-04-01

Three varieties of golden kiwifruit (Actinidia chinensis) (Gold3, Gold9 and Hort16A) were collected at the commercial harvesting time, and physicochemical properties of starches from core and outer pericarp were studied. Starch contents (dry weight basis) in outer pericarp and core tissues ranged from 38.6 to 51.8% and 34.6 to 40.7%, respectively. All the kiwifruit starches showed B-type polymorph. Compared to the outer pericarp starches, amylose content and enzyme susceptibility of core starches were higher, and the degree of crystallinity, granule size and gelatinization parameters of core starches were somewhat lower. This suggests different biosynthetic properties between these two starches. The enthalpy changes of gelatinization of outer pericarp starches were high (∼21J/g). Rheological properties of outer pericarp starches were compared with normal maize and potato starches showed high yield stress of flow properties. This study revealed the unique properties of kiwifruit starch among various types of starches. Copyright © 2016 Elsevier Ltd. All rights reserved.

78 FR 76643 - Atlantic Wind Lease Sale 3 (ATLW3) Commercial Leasing for Wind Power on the Outer Continental...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-18

...: Nameplate capacity is the maximum rated electric output, expressed in MW, which the turbines of the wind facility under commercial operations can produce at their rated wind speed as designated by the turbine's...; MMAA104000] Atlantic Wind Lease Sale 3 (ATLW3) Commercial Leasing for Wind Power on the Outer Continental...

Normal Mode Derived Models of the Physical Properties of Earth's Outer Core

NASA Astrophysics Data System (ADS)

Irving, J. C. E.; Cottaar, S.; Lekic, V.; Wu, W.

2017-12-01

Earth's outer core, the largest reservoir of metal in our planet, is comprised of an iron alloy of an uncertain composition. Its dynamical behaviour is responsible for the generation of Earth's magnetic field, with convection driven both by thermal and chemical buoyancy fluxes. Existing models of the seismic velocity and density of the outer core exhibit some variation, and there are only a small number of models which aim to represent the outer core's density.It is therefore important that we develop a better understanding of the physical properties of the outer core. Though most of the outer core is likely to be well mixed, it is possible that the uppermost outer core is stably stratified: it may be enriched in light elements released during the growth of the solid, iron enriched, inner core; by elements dissolved from the mantle into the outer core; or by exsolution of compounds previously dissolved in the liquid metal which will eventually be swept into the mantle. The stratified layer may host MAC or Rossby waves and it could impede communication between the chemically differentiated mantle and outer core, including screening out some of the geodynamo's signal. We use normal mode center frequencies to estimate the physical properties of the outer core in a Bayesian framework. We estimate the mineral physical parameters needed to best produce velocity and density models of the outer core which are consistent with the normal mode observations. We require that our models satisfy realistic physical constraints. We create models of the outer core with and without a distinct uppermost layer and assess the importance of this region.Our normal mode-derived models are compared with observations of body waves which travel through the outer core. In particular, we consider SmKS waves which are especially sensitive to the uppermost outer core and are therefore an important way to understand the robustness of our models.

Unilateral Outer Bow Expanded Cervical Headgear Force System: 3D Analysis Using Finite Element Method

PubMed Central

Mortezai, Omid; Esmaily, Masomeh; Darvishpour, Hojat

2015-01-01

Objectives: Headgears are among the effective orthodontic appliances to achieve treatment goals. Unilateral molar distal movement is sometimes needed during an orthodontic treatment, which can be achieved by an asymmetric headgear. Different unilateral headgears have been introduced. The main goal of this study was to analyze the force system of unilateral expanded outer bow asymmetric headgears by the finite element method (FEM). Materials and Methods: Six 3D finite element models of a mesiodistal slice of the maxilla containing upper first molars, their periodontal ligaments (PDLs), cancellous bone, cortical bone, and a cervical headgear with expanded outer bow attached to maxillary first molars were designed in SolidWorks 2010 and meshed in ANSYS Workbench ver. 12.1. The models were the same except for the degree of outer bow expansion. The outer bow ends were loaded with 2 N force. The distal driving force and the net moment were evaluated. Results: A decrease in the distalizing force in the normal side molar from 1.69 N to 1.37 N was shown by increasing the degree of unilateral expansion. At the same time, the force increased from 2.19 N to 2.49 N in the expanded side molar. A net moment increasing from 2.26 N.mm to 4.64 N.mm was also shown. Conclusion: Unilateral outer bow expansion can produce different distalizing forces in molars, which increase by increasing the expansion. PMID:26622282

76 FR 2919 - Outer Continental Shelf Official Protraction Diagram and Supplemental Official Outer Continental...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-18

...: Availability of Revised North American Datum of 1983 (NAD 83) Outer Continental Shelf Official Protraction... that effective with this publication, the following NAD 83-based Outer Continental Shelf (OCS) Official...

A Deficiency in Arabinogalactan Biosynthesis Affects Corynebacterium glutamicum Mycolate Outer Membrane Stability▿

PubMed Central

Bou Raad, Roland; Méniche, Xavier; de Sousa-d'Auria, Celia; Chami, Mohamed; Salmeron, Christophe; Tropis, Marielle; Labarre, Cecile; Daffé, Mamadou; Houssin, Christine; Bayan, Nicolas

2010-01-01

Corynebacterineae is a specific suborder of Gram-positive bacteria that includes Mycobacterium tuberculosis and Corynebacterium glutamicum. The ultrastructure of the cell envelope is very atypical. It is composed of a heteropolymer of peptidoglycan and arabinogalactan (AG) covalently associated to an outer membrane. Five arabinosyltransferases are involved in the biosynthesis of AG in C. glutamicum. AftB catalyzes the transfer of Araf (arabinofuranosyl) onto the arabinan domain of the arabinogalactan to form terminal β(1 → 2)-linked Araf residues. Here we show that ΔaftB cells lack half of the arabinogalactan mycoloylation sites but are still able to assemble an outer membrane. In addition, we show that a ΔaftB mutant grown on a rich medium has a perturbed cell envelope and sheds a significant amount of membrane fragments in the external culture medium. These fragments contain mono- and dimycolate of trehalose and PorA/H, the major porin of C. glutamicum, but lack conventional phospholipids that typify the plasma membrane, suggesting that they are derived from the atypical mycolate outer membrane of the cell envelope. This is the first report of outer membrane destabilization in the Corynebacterineae, and it suggests that a strong interaction between the mycolate outer membrane and the underlying polymer is essential for cell envelope integrity. The presence of outer membrane-derived fragments (OMFs) in the external medium of the ΔaftB mutant is also a very promising tool for outer membrane characterization. Indeed, fingerprint analysis of major OMF-associated proteins has already led to the identification of 3 associated mycoloyltransferases and an unknown protein with a C-terminal hydrophobic anchoring domain reminiscent of that found for the S-layer protein PS2 of C. glutamicum. PMID:20363942

Bidirectional chaos communication between two outer semiconductor lasers coupled mutually with a central semiconductor laser.

PubMed

Li, Ping; Wu, Jia-Gui; Wu, Zheng-Mao; Lin, Xiao-Dong; Deng, Dao; Liu, Yu-Ran; Xia, Guang-Qiong

2011-11-21

Based on a linear chain composed of a central semiconductor laser and two outer semiconductor lasers, chaos synchronization and bidirectional communication between two outer lasers have been investigated under the case that the central laser and the two outer lasers are coupled mutually, whereas there exists no coupling between the two outer lasers. The simulation results show that high-quality and stable isochronal synchronization between the two outer lasers can be achieved, while the cross-correlation coefficients between the two outer lasers and the central laser are very low under proper operation condition. Based on the high performance chaos synchronization between the two outer lasers, message bidirectional transmissions of bit rates up to 20 Gbit/s can be realized through adopting a novel decoding scheme which is different from that based on chaos pass filtering effect. Furthermore, the security of bidirectional communication is also analyzed. © 2011 Optical Society of America

Light induces a rapid and transient increase in inositol-trisphosphate in toad rod outer segments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, J.E.; Blazynski, C.; Cohen, A.I.

1987-08-14

The sub-second time course of changes in the content of (/sup 3/H)inositol-1,4,5-trisphosphate was determined in rod outer segments from very rapidly frozen Bufo retinas that had been incubated with (/sup 3/H)inositol. Rod outer segments were cut off frozen specimens with a cryostat microtome and the water soluble extracts were analyzed. The content of (/sup 3/H)inositol-1,4,5-trisphosphate rose after approximately 250 msec of bright illumination, but returned to the unstimulated level after 1 sec, whether the stimulus remained on or not. That is, there was rapid but transient change in the content of (/sup 3/H)inositol-1,4,5-trisphosphate after the onset of stimulation.

Elimination of Lifetime Limiting Mechanism of Hall Thrusters

NASA Technical Reports Server (NTRS)

Jacobson, David T. (Inventor); Manzella, David H. (Inventor)

2009-01-01

A Hall thruster includes inner and outer electromagnets, with the outer electromagnet circumferentially surrounding the inner electromagnet along a centerline axis and separated therefrom, inner and outer poles, in physical connection with their respective inner and outer electromagnets, with the inner pole having a mostly circular shape and the outer pole having a mostly annular shape, a discharge chamber separating the inner and outer poles, a combined anode electrode/gaseous propellant distributor, located at an upstream portion of the discharge chamber and supplying propellant gas and an actuator, in contact with a sleeve portion of the discharge chamber. The actuator is configured to extend the sleeve portion or portions of the discharge chamber along the centerline axis with respect to the inner and outer poles.

76 FR 54787 - Outer Continental Shelf Official Protraction Diagram, Lease Maps, and Supplemental Official Outer...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-02

.... ACTION: Availability of revised North American Datum of 1927 (NAD 27) Outer Continental Shelf Official...: Notice is hereby given that effective with this publication, the following NAD 27-based Outer Continental...

Origin of Outer Solar System

NASA Technical Reports Server (NTRS)

Holman, Matthew J.; Lindstrom, David (Technical Monitor)

2005-01-01

Our ongoing research program combines extensive deep and wide-field observations using a variety of observational platforms with numerical studies of the dynamics of small bodies in the outer solar system in order to advance the main scientific goals of the community studying the Kuiper belt and the outer solar system. These include: (1) determining the relative populations of the known classes of KBOs as well as other possible classes; ( 2 ) determining the size distributions or luminosity function of the individual populations or the Kuiper belt as a whole; (3) determining the inclinations distributions of these populations; (4) establishing the radial extent of the Kuiper belt; ( 5 ) measuring and relating the physical properties of different types of KBOs to those of other solar system bodies; and, (6) completing our systematic inventory of the satellites of the outer planets.

High voltage coaxial switch

DOEpatents

Rink, J.P.

1983-07-19

A coaxial high voltage, high current switch having a solid cylindrical cold cathode coaxially surrounded by a thin hollow cylindrical inner electrode and a larger hollow cylindrical outer electrode. A high voltage trigger between the cathode and the inner electrode causes electrons to be emitted from the cathode and flow to the inner electrode preferably through a vacuum. Some of the electrons penetrate the inner electrode and cause a volumetric discharge in the gas (which may be merely air) between the inner and outer electrodes. The discharge provides a low impedance path between a high voltage charge placed on the outer electrode and a load (which may be a high power laser) coupled to the inner electrode. For high repetition rate the gas between the inner and outer electrodes may be continuously exchanged or refreshed under pressure. 3 figs.

Using Real and Simulated TNOs to Constrain the Outer Solar System

NASA Astrophysics Data System (ADS)

Kaib, Nathan

2018-04-01

Over the past 2-3 decades our understanding of the outer solar system’s history and current state has evolved dramatically. An explosion in the number of detected trans-Neptunian objects (TNOs) coupled with simultaneous advances in numerical models of orbital dynamics has driven this rapid evolution. However, successfully constraining the orbital architecture and evolution of the outer solar system requires accurately comparing simulation results with observational datasets. This process is challenging because observed datasets are influenced by orbital discovery biases as well as TNO size and albedo distributions. Meanwhile, such influences are generally absent from numerical results. Here I will review recent work I and others have undertaken using numerical simulations in concert with catalogs of observed TNOs to constrain the outer solar system’s current orbital architecture and past evolution.

Quantitative evaluation of bone development of the distal phalanx of the cow hind limb using computed tomography.

PubMed

Tsuka, T; Ooshita, K; Sugiyama, A; Osaki, T; Okamoto, Y; Minami, S; Imagawa, T

2012-01-01

Computed tomography (CT) was performed on 400 claws (200 inner and 200 outer claws) of 100 pairs of bovine hind limbs to investigate the etiological theory that an exacerbating factor for ulceration is exostosis of the tuberculum flexorium within the distal phalanx. A variety of morphological changes of the tuberculum flexorium of bovine hind limb claws was visualized by 3-dimensional CT, and the geometry of these claws suggested a growth pattern of bone development with respect to the assumed daily loading patterns. This growth occurs initially at the abaxial caudal aspect of the distal phalanx and is followed by horizontal progression toward the axial aspect. The length of downward bone development on the solar face of the distal phalanx was 2.73±1.32 mm in the outer claws, significantly greater than in the inner claws (2.38±0.96 mm). Ratios of downward (vertical) bone development to the thickness of the subcutis and the corium (VerBD ratios) did not differ between the outer and inner claws (36.7 vs. 38.3%, respectively). Ratios of horizontal bone development to the axial-to-abaxial line of the tuberculum flexorium (HorBD ratios) were approximately 60% for both outer and inner claws. These quantitative measures regarding horizontal and vertical bone development within the distal phalanx were positively correlated with age and VerBD ratios (r=0.53 and r=0.36 for the inner and outer claws, respectively). Correlations between claw width of the outer claw and length of vertical bone development (r=0.43), the HorBD ratio (r=0.51), and the VerBD ratio (r=0.42) suggested that the relative size difference between the inner and outer claws enhances bone development in the outer claw. Correlation coefficients between VerBD and HorBD ratios (r=0.52 and 0.63 for the inner and outer claws, respectively) suggested that horizontal and vertical bone development occurs as a synchronized process within the tuberculum flexorium. This age-related progress of bone development within the tuberculum flexorium is associated with increased exposure to several exacerbating factors and the laminitic process. Copyright © 2012 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Ultrasonic isolation of the outer membrane of Escherichia coli with autodisplayed Z-domains.

PubMed

Bong, Ji-Hong; Yoo, Gu; Park, Min; Kang, Min-Jung; Jose, Joachim; Pyun, Jae-Chul

2014-11-01

The outer membrane of Escherichia coli was previously isolated as a liposome-like outer membrane particle using an enzymatic treatment for lysozymes; for immunoassays, the particles were subsequently layered on solid supports via hydrophobic interactions. This work presents an enzyme-free isolation method for the E. coli outer membrane with autodisplayed Z-domains using ultrasonication. First, the properties of the outer membrane particle, such as the particle size, zeta potential, and total protein, were compared with the properties of particles obtained using the previous preparation methods. Compared with the conventional isolation method using an enzyme treatment, the ultrasonic method exhibited a higher efficiency at isolating the outer membrane and less contamination by cytosolic proteins. The isolated outer membrane particles were layered on a gold surface, and the roughness and thickness of the layered outer membrane layers were subsequently analyzed using AFM analysis. Finally, the antibody-binding activity of two outer membrane layers with autodisplayed Z-domains created from particles that were isolated using the enzymatic and ultrasonic isolation methods was measured using fluorescein-labeled antibody as a model analyte, and the activity of the outer membrane layer that was isolated from the ultrasonic method was estimated to be more than 20% higher than that from the conventional enzymatic method. Copyright © 2014 Elsevier Inc. All rights reserved.

Dual character of Sundarban estuary as a source and sink of CO2 during summer: an investigation of spatial dynamics.

PubMed

Akhand, Anirban; Chanda, Abhra; Dutta, Sachinandan; Manna, Sudip; Sanyal, Pranabes; Hazra, Sugata; Rao, K H; Dadhwal, V K

2013-08-01

A comprehensive attempt has been made to evaluate the diurnal and spatial pattern of CO2 exchange between the atmosphere and water along the estuarine track of Indian Sundarbans during the two summer months, April and May, 2011. Rigorous field observations were carried out which included the hourly measurements of total alkalinity, pH, fugacity of CO2 in ambient air and water surface, dissolved oxygen, and chlorophyll a. The estuarine water was found rich in total alkalinity and was oversaturated with CO2 throughout the diurnal cycle in the two stations situated at the inner and middle estuary, respectively, whereas an entirely reverse situation was observed in the outer fringes. The fugacity of CO2 in water ranged from 152 to 657 μatm during the study period. The percentage of over-saturation in inner and middle estuary varied from 103 to 168 and 103 to 176 %, respectively, whereas the degree of under-saturation in the outer estuary lied between 40 and 99 %. Chlorophyll a concentrations were found higher in the outer estuary (12.3 ± 2.2 mg m(-3)) compared to the middle (6.4 ± 0.6 mg m(-3)) and inner parts (1.6 ± 0.2 mg m(-3)), followed by a similar decreasing pattern in nutrient availability from the outer to inner estuary. The sampling stations situated at the inner and middle estuary acted as a net source of 29.69 and 23.62 mg CO2 m(-2) day(-1), respectively, whereas the outer station behaved as a net sink of -33.37 mg CO2 m(-2) day(-1). The study of primary production and community respiration further supports the heterotrophic nature of the estuary in the inner region while the outer periphery was marked by dominant autotrophic character. These contrasting results are in parity with the source characters of many inner estuaries and sinking characters of the outer estuaries situated at the distal continental shelf areas.

Effect of two inner-ring oil-flow distribution schemes on the operating characteristics of a 35 millimeter bore ball bearing to 2.5 million DN

NASA Technical Reports Server (NTRS)

Schuller, F. T.; Pinel, S. I.; Signer, H. R.

1985-01-01

Parametric tests were conducted with a 35-mm-bore, split-inner-ring ball bearing with a double-inner-land-guided cage. Provisions were made for through-the-inner-ring lubrication. Test condictions were either a thrust load of 667 N (150 lb) or a combined load of 667 N (150 lb) thrust and 222 N (50 lb) radial, shaft speeds from 32000 to 72000 rpm, and an oil-inlet temperature of 394 K (250 deg F). Outer ring cooling was used in some tests. Tests were run with either 50 or 75 percent of the total oil flow distributed to the inner-ring raceway. Successful operation was experienced with both 50% and 75% flow patterns to 2.5 million DN. Cooling the outer ring had little effect on inner-ring temperature; however, the outer-ring temperature decreased as much as 7% at 2.5 million DN. Maximum recorded power loss was 3.1 kW (4.2 hp), and maximum cage slip was 8.7 percent. Both occurred at a shaft speed of 72000 rpm, a lubricant flow rate of 1900 cu/min (0.50 gal/min), a combined load, and no outer-ring cooling.

A DFT investigation of a bulky biomimetic model catalyzing the 5'-outer ring deiodination of thyroxine.

PubMed

Fortino, Mariagrazia; Marino, Tiziana; Russo, Nino; Sicilia, Emilia

2016-12-01

This paper illustrates the outcomes of a density functional theory investigation aimed at unraveling mechanistic aspects of the 5'-outer ring deiodination process of thyroxine (T4) assisted by the sterically protected organoselenol compound BpqSeH. BpqSeH, which was previously synthesized and tested for its deiodinase activity, is able to afford the active hormone 3,5,3'-tetraiodothyronine (T3) by selective outer-ring deiodination of T4, and to protect the SeH moiety inside the nano-sized molecular cavity from further reactivity, allowing its isolation and characterization. Calculations were also performed including an imidazole ring that, mimicking a His residue in the active site of the original enzyme, plays an crucial role in deprotonating the selenol moiety. Both the suggested enol/keto tautomerization and the previously proven formation of an intermediate whose main characteristic is the presence of a Se⋯I⋯C halogen bond, were examined along the pathway leading to 5'-outer ring deiodination. The calculated potential energy surface showed that neither the pathway encompassing enol/keto tautomerism nor the formation of a halogen bond paving the way to C-I bond breaking and chalcogen-I bond forming is viable. The exergonic formation of the final selenenyl iodide product confirms the stabilization effect of the molecular cavity. Graphical Abstract Computed free energy profile describing the 5'-outer deiodination of thyroxine assisted by the steric hindered organoselenol BpqSH compound. The molecular electrostatic potential map reoported for the INT1 intermediate shows the non-covalent Se-I interaction, due to the attraction between charges of opposite sign, that weakens the C-I bond and prepares the formation of the new Se-I bond.

Molecular Clouds in the Extreme Outer Galaxy between l  = 34.°75 to 45.°25

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, Yan; Su, Yang; Zhang, Shao-Bo

We present the results of an unbiased CO survey in the Galactic range of 34.°75 ≤  l  ≤ 45.°25 and −5.°25 ≤  b  ≤ 5.°25, and the velocity range beyond the Outer arm. A total of 168 molecular clouds (MCs) are identified within the Extreme Outer Galaxy (EOG) region, and 31 of these MCs are associated with {sup 13}CO  emission. However, none of them show significant C{sup 18}O  emission under the current detection limit. The typical size and mass of these MCs are 5 pc and 3 × 10{sup 3} M {sub ⊙}, implying a lack of large and massive MCs in the EOG region. Similar to MCsmore » in the outer Galaxy, the velocity dispersions of EOG clouds are also correlated with their sizes; however, they are well displaced below the scaling relationship defined by the inner Galaxy MCs. These MCs with a median Galactocentric radius of 12.6 kpc show very different distributions from those of the MCs in the Outer arm published in our previous paper, while roughly following the Outer Scutum–Centaurus arm defined by Dame and Thaddeus. This result may provide robust evidence for the existence of the Outer Scutum–Centaurus arm. The lower limit of the total mass of this segment is about 2.7 × 10{sup 5} M {sub ⊙}, which is about one magnitude lower than that of the Outer arm. The mean thickness of the gaseous disk is about 1.°45 or 450 pc, and the scale height is about 1.°27, or 400 pc above the b  = 0° plane. The warp traced by CO emission is very obvious in the EOG region and its amplitude is consistent with the predictions by other warp models using different tracers, such as dust, H i, and stellar components of our Galaxy.« less

Quantitative evaluation of the relationship between dorsal wall length, sole thickness, and rotation of the distal phalanx in the bovine claw using computed tomography.

PubMed

Tsuka, T; Murahata, Y; Azuma, K; Osaki, T; Ito, N; Okamoto, Y; Imagawa, T

2014-10-01

Computed tomography (CT) was performed on 800 untrimmed claws (400 inner claws and 400 outer claws) of 200 pairs of bovine hindlimbs to investigate the relationships between dorsal wall length and sole thickness, and between dorsal wall length and the relative rotation angle of distal phalanx-to-sole surface (S-D angle). Sole thickness was 3.8 and 4.0 mm at the apex of the inner claws and outer claws, respectively, with dorsal wall lengths <70 mm. These sole thickness values were less than the critical limit of 5 mm, which is associated with a softer surface following thinning of the soles. A sole thickness of 5 mm at the apex was estimated to correlate with dorsal wall lengths of 72.1 and 72.7 mm for the inner and outer claws, respectively. Sole thickness was 6.1 and 6.4 mm at the apex of the inner and outer claws, respectively, with dorsal wall lengths of 75 mm. These sole thickness values were less than the recommended sole thickness of 7 mm based on the protective function of the soles. A sole thickness >7 mm at the apex was estimated to correlate with a dorsal wall length of 79.8 and 78.4mm for the inner and outer claws, respectively. The S-D angles were recorded as anteversions of 2.9° and 4.7° for the inner and outer claws, respectively, with a dorsal wall length of 75 mm. These values indicate that the distal phalanx is likely to have rotated naturally forward toward the sole surface. The distal phalanx rotated backward to the sole surface at 3.2° and 7.6° for inner claws with dorsal wall lengths of 90-99 and ≥100 mm, respectively; and at 3.5° for outer claws with a dorsal wall length ≥100 mm. Dorsal wall lengths of 85.7 and 97.2 mm were estimated to correlate with a parallel positional relationship of the distal phalanx to the sole surface in the inner and outer claws, respectively. Copyright © 2014 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Gas turbine combustor

NASA Technical Reports Server (NTRS)

Burd, Steven W. (Inventor); Cheung, Albert K. (Inventor); Dempsey, Dae K. (Inventor); Hoke, James B. (Inventor); Kramer, Stephen K. (Inventor); Ols, John T. (Inventor); Smith, Reid Dyer Curtis (Inventor); Sowa, William A. (Inventor)

2011-01-01

A gas turbine engine has a combustor module including an annular combustor having a liner assembly that defines an annular combustion chamber having a length, L. The liner assembly includes a radially inner liner, a radially outer liner that circumscribes the inner liner, and a bulkhead, having a height, H1, which extends between the respective forward ends of the inner liner and the outer liner. The combustor has an exit height, H3, at the respective aft ends of the inner liner and the outer liner interior. The annular combustor has a ratio H1/H3 having a value less than or equal to 1.7. The annular combustor may also have a ration L/H3 having a value less than or equal to 6.0.

Will Outer Tropical Cyclone Size Change due to Anthropogenic Warming?

NASA Astrophysics Data System (ADS)

Schenkel, B. A.; Lin, N.; Chavas, D. R.; Vecchi, G. A.; Knutson, T. R.; Oppenheimer, M.

2017-12-01

Prior research has shown significant interbasin and intrabasin variability in outer tropical cyclone (TC) size. Moreover, outer TC size has even been shown to vary substantially over the lifetime of the majority of TCs. However, the factors responsible for both setting initial outer TC size and determining its evolution throughout the TC lifetime remain uncertain. Given these gaps in our physical understanding, there remains uncertainty in how outer TC size will change, if at all, due to anthropogenic warming. The present study seeks to quantify whether outer TC size will change significantly in response to anthropogenic warming using data from a high-resolution global climate model and a regional hurricane model. Similar to prior work, the outer TC size metric used in this study is the radius in which the azimuthal-mean surface azimuthal wind equals 8 m/s. The initial results from the high-resolution global climate model data suggest that the distribution of outer TC size shifts significantly towards larger values in each global TC basin during future climates, as revealed by 1) statistically significant increase of the median outer TC size by 5-10% (p<0.05) according to a 1,000-sample bootstrap resampling approach with replacement and 2) statistically significant differences between distributions of outer TC size from current and future climate simulations as shown using two-sample Kolmogorov Smirnov testing (p<<0.01). Additional analysis of the high-resolution global climate model data reveals that outer TC size does not uniformly increase within each basin in future climates, but rather shows substantial locational dependence. Future work will incorporate the regional mesoscale hurricane model data to help focus on identifying the source of the spatial variability in outer TC size increases within each basin during future climates and, more importantly, why outer TC size changes in response to anthropogenic warming.

Pyrometer mount for a closed-circuit thermal medium cooled gas turbine

DOEpatents

Jones, Raymond Joseph; Kirkpatrick, Francis Lawrence; Burns, James Lee; Fulton, John Robert

2002-01-01

A steam-cooled second-stage nozzle segment has an outer band and an outer cover defining a plenum therebetween for receiving cooling steam for flow through the nozzles to the inner band and cover therefor and return flow through the nozzles. To measure the temperature of the buckets of the stage forwardly of the nozzle stage, a pyrometer boss is electron beam-welded in an opening through the outer band and TIG-welded to the outer cover plate. By machining a hole through the boss and seating a linearly extending tube in the boss, a line of sight between a pyrometer mounted on the turbine frame and the buckets is provided whereby the temperature of the buckets can be ascertained. The welding of the boss to the outer band and outer cover enables steam flow through the plenum without leakage, while providing a line of sight through the outer cover and outer band to measure bucket temperature.

Error Control Coding Techniques for Space and Satellite Communications

NASA Technical Reports Server (NTRS)

Lin, Shu

2000-01-01

This paper presents a concatenated turbo coding system in which a Reed-Solomom outer code is concatenated with a binary turbo inner code. In the proposed system, the outer code decoder and the inner turbo code decoder interact to achieve both good bit error and frame error performances. The outer code decoder helps the inner turbo code decoder to terminate its decoding iteration while the inner turbo code decoder provides soft-output information to the outer code decoder to carry out a reliability-based soft-decision decoding. In the case that the outer code decoding fails, the outer code decoder instructs the inner code decoder to continue its decoding iterations until the outer code decoding is successful or a preset maximum number of decoding iterations is reached. This interaction between outer and inner code decoders reduces decoding delay. Also presented in the paper are an effective criterion for stopping the iteration process of the inner code decoder and a new reliability-based decoding algorithm for nonbinary codes.

An Interactive Concatenated Turbo Coding System

NASA Technical Reports Server (NTRS)

Liu, Ye; Tang, Heng; Lin, Shu; Fossorier, Marc

1999-01-01

This paper presents a concatenated turbo coding system in which a Reed-Solomon outer code is concatenated with a binary turbo inner code. In the proposed system, the outer code decoder and the inner turbo code decoder interact to achieve both good bit error and frame error performances. The outer code decoder helps the inner turbo code decoder to terminate its decoding iteration while the inner turbo code decoder provides soft-output information to the outer code decoder to carry out a reliability-based soft- decision decoding. In the case that the outer code decoding fails, the outer code decoder instructs the inner code decoder to continue its decoding iterations until the outer code decoding is successful or a preset maximum number of decoding iterations is reached. This interaction between outer and inner code decoders reduces decoding delay. Also presented in the paper are an effective criterion for stopping the iteration process of the inner code decoder and a new reliability-based decoding algorithm for nonbinary codes.

Ferrules seals

DOEpatents

Smith, J.L.

1984-07-10

A device is provided for sealing an inner tube and an outer tube without excessively deforming the tubes. The device includes two ferrules which cooperate to form a vacuum-tight seal between the inner tube and outer tube and having mating surfaces such that overtightening is not possible. 3 figs.

Investigation, development and application of optimal output feedback theory. Volume 2: Development of an optimal, limited state feedback outer-loop digital flight control system for 3-D terminal area operation

NASA Technical Reports Server (NTRS)

Broussard, J. R.; Halyo, N.

1984-01-01

This report contains the development of a digital outer-loop three dimensional radio navigation (3-D RNAV) flight control system for a small commercial jet transport. The outer-loop control system is designed using optimal stochastic limited state feedback techniques. Options investigated using the optimal limited state feedback approach include integrated versus hierarchical control loop designs, 20 samples per second versus 5 samples per second outer-loop operation and alternative Type 1 integration command errors. Command generator tracking techniques used in the digital control design enable the jet transport to automatically track arbitrary curved flight paths generated by waypoints. The performance of the design is demonstrated using detailed nonlinear aircraft simulations in the terminal area, frequency domain multi-input sigma plots, frequency domain single-input Bode plots and closed-loop poles. The response of the system to a severe wind shear during a landing approach is also presented.

Is "black geode" sign a characteristic MRI finding for extracranial schwannomas?

PubMed

Kato, Hiroki; Kanematsu, Masayuki; Ohno, Takatoshi; Nishimoto, Yutaka; Oshima, Koji; Hirose, Yoshinobu; Nishibori, Hironori

2013-04-01

To evaluate whether the "black geode" sign is a characteristic magnetic resonance imaging (MRI) finding for extracranial schwannomas. Forty-three patients with pathologically confirmed extracranial schwannomas underwent preoperative gadolinium-enhanced MRI. The black geode sign was defined as the appearance of enhanced outer and inner rings. MR images were retrospectively reviewed for size, configuration, and signal intensity of the lesions in addition to the presence of the black geode sign. Gadolinium-enhanced T1-weighted images revealed the black geode sign in seven of 43 patients (16%). The thickness of inner rings (mean 0.6 cm, range 0.3-0.8 cm) was significantly greater than that of outer rings (mean 0.2 cm, range 0.1-0.3 cm) (P < 0.01). While outer rings were circular or elliptical in shape with smooth contours, inner rings had a lobular configuration with irregular thickness and contours. The degrees of enhancement were significantly stronger with inner rings than with outer rings (P < 0.01). In histopathological correlation of five patients who underwent total excision, inner and outer rings corresponded to peridegenerative areas and fibrous capsules, respectively. The black geode sign may be fairly specific to extracranial schwannomas on gadolinium-enhanced MR images. Copyright © 2012 Wiley Periodicals, Inc.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tang, Ya-Wen; Dutrey, Anne; Guilloteau, Stéphane

We aim to unveil the observational imprint of physical mechanisms that govern planetary formation in the young, multiple system GG Tau A. We present ALMA observations of {sup 12}CO and {sup 13}CO 3–2 and 0.9 mm continuum emission with 0.″35 resolution. The {sup 12}CO 3–2 emission, found within the cavity of the circumternary dust ring (at radius <180 au) where no {sup 13}CO emission is detected, confirms the presence of CO gas near the circumstellar disk of GG Tau Aa. The outer disk and the recently detected hot spot lying at the outer edge of the dust ring are mappedmore » both in {sup 12}CO and {sup 13}CO. The gas emission in the outer disk can be radially decomposed as a series of slightly overlapping Gaussian rings, suggesting the presence of unresolved gaps or dips. The dip closest to the disk center lies at a radius very close to the hot spot location at ∼250–260 au. The CO excitation conditions indicate that the outer disk remains in the shadow of the ring. The hot spot probably results from local heating processes. The two latter points reinforce the hypothesis that the hot spot is created by an embedded proto-planet shepherding the outer disk.« less

Optical power splitter and polarization splitter

NASA Technical Reports Server (NTRS)

Bogert, Gail A. (Inventor)

1988-01-01

A 3.times.3 optical guiding arrangement is disclosed for providing both power splitting between a pair of output guides in the 3.times.3 guide structure and polarization splitting (into the TE and TM modes) between the central guide and the pair of outer guides. In accordance with the present invention, the mutual coupling length L and separation distance d between adjacent guides are chosen to provide the desired polarization splitting and total intensity (power) in the outer guides. For example, an input signal of intensity I comprising both the TE and TM modes may be launched in the center guide and with correct choices for L and d, will result in output signals of I.sub.TM /2 each of the outer pair of guides and I.sub.TE from the central guide.

Apparatus and filtering systems relating to combustors in combustion turbine engines

DOEpatents

Johnson, Thomas Edward [Greer, SC; Zuo, Baifang [Simpsonville, SC; Stevenson, Christian Xavier [Inman, SC

2012-07-24

A combustor for a combustion turbine engine, the combustor that includes: a chamber defined by an outer wall and forming a channel between windows defined through the outer wall toward a forward end of the chamber and at least one fuel injector positioned toward an aft end of the chamber; a screen; and a standoff comprising a raised area on an outer surface of the outer wall near the periphery of the windows; wherein the screen extends over the windows and is supported by the standoff in a raised position in relation to the outer surface of the outer wall and the windows.

Outer Membrane Permeability of Cyanobacterium Synechocystis sp. Strain PCC 6803: Studies of Passive Diffusion of Small Organic Nutrients Reveal the Absence of Classical Porins and Intrinsically Low Permeability

PubMed Central

Kowata, Hikaru; Tochigi, Saeko; Takahashi, Hideyuki

2017-01-01

ABSTRACT The outer membrane of heterotrophic Gram-negative bacteria plays the role of a selective permeability barrier that prevents the influx of toxic compounds while allowing the nonspecific passage of small hydrophilic nutrients through porin channels. Compared with heterotrophic Gram-negative bacteria, the outer membrane properties of cyanobacteria, which are Gram-negative photoautotrophs, are not clearly understood. In this study, using small carbohydrates, amino acids, and inorganic ions as permeation probes, we determined the outer membrane permeability of Synechocystis sp. strain PCC 6803 in intact cells and in proteoliposomes reconstituted with outer membrane proteins. The permeability of this cyanobacterium was >20-fold lower than that of Escherichia coli. The predominant outer membrane proteins Slr1841, Slr1908, and Slr0042 were not permeable to organic nutrients and allowed only the passage of inorganic ions. Only the less abundant outer membrane protein Slr1270, a homolog of the E. coli export channel TolC, was permeable to organic solutes. The activity of Slr1270 as a channel was verified in a recombinant Slr1270-producing E. coli outer membrane. The lack of putative porins and the low outer membrane permeability appear to suit the cyanobacterial autotrophic lifestyle; the highly impermeable outer membrane would be advantageous to cellular survival by protecting the cell from toxic compounds, especially when the cellular physiology is not dependent on the uptake of organic nutrients. IMPORTANCE Because the outer membrane of Gram-negative bacteria affects the flux rates for various substances into and out of the cell, its permeability is closely associated with cellular physiology. The outer membrane properties of cyanobacteria, which are photoautotrophic Gram-negative bacteria, are not clearly understood. Here, we examined the outer membrane of Synechocystis sp. strain PCC 6803. We revealed that it is relatively permeable to inorganic ions but is markedly less permeable to organic nutrients, with >20-fold lower permeability than the outer membrane of Escherichia coli. Such permeability appears to fit the cyanobacterial lifestyle, in which the diffusion pathway for inorganic solutes may suffice to sustain the autotrophic physiology, illustrating a link between outer membrane permeability and the cellular lifestyle. PMID:28696278

Ground Based Studies of the Outer Planets

NASA Technical Reports Server (NTRS)

Trafton, Laurence M.

2005-01-01

This report covers progress to date under this grant on our continuing program to conduct ground based studies of the outer solar system planets and satellites, with emphasis on spectroscopy and atmospheric phenomena. The research continues under our new PAST grant, NNG04G131G beginning 5/1/2004. The original period of performance of the subject grant was 3/1/2001 to 2/28/2004, but was extended one year at no cost. Although there is some overlap in the scientific projects conducted during the extended year with those of the new grant, this report is confined to the portion of the work funded under NAG5-10435. The primary goals for this grant period were a comparative study of outer planet thermospheres/ionospheres near solar maximum, extended to the mid-IR, and the investigation of molecular dimers in outer solar system atmospheres. This project supports NASA's planned space missions, Jupiter Polar Orbiter, outer Planet Microprobes, and the recent Cassini flyby of Jupiter. It also supports the OSS strategic plan themes, The Exploration of the Solar System and The Sun-Earth Connection/ Understanding comparative planetary space environments.

LGM-30B, Stage II Dissected Motors Test Report,

DTIC Science & Technology

1980-07-01

Relaxation Test Data (Outer Propellant) 29 Table 9, Stress Relaxation Test Data (Inner Propellant) 31 Table 10 , Cohesive Tear Energy Test Data (Outer...Outer) 45 7 Maximum Stress (Inner) 46 8Strain at Rupture (Inner) 47 9 Modulus (Inner) 48 Regression Plot, Low Rate Tensile 10 Maximum Stress (Outer...outer propellants are almost the same. H. TEAR ENERGY TEST: Data from this test period are contained in Tables 10 and 11. Sufficient valid data became

Particle trap with dielectric barrier for use in gas insulated transmission lines

DOEpatents

Dale, Steinar J.

1982-01-01

A gas-insulated transmission line includes an outer sheath, an inner conductor within the outer sheath, insulating supports supporting the inner conductor within the outer sheath, and an insulating gas electrically insulating the inner conductor from the outer sheath. An apertured particle trapping electrode is disposed within the outer sheath, and the electrode has a pair of dielectric members secured at each longitudinal end thereof, with the dielectric members extending outwardly from the apertured electrode.

Growth of farmed blue mussels ( Mytilus edulis L.) in a Norwegian coastal area; comparison of food proxies by DEB modeling

NASA Astrophysics Data System (ADS)

Handå, Aleksander; Alver, Morten; Edvardsen, Christian Vik; Halstensen, Stein; Olsen, Anders Johny; Øie, Gunvor; Reitan, Kjell Inge; Olsen, Yngvar; Reinertsen, Helge

2011-11-01

Seston variables and growth of the blue mussel ( Mytilus edulis L.) were measured during the growth season from March to October in three suspended longline farms in Central Norway; one in the inner part of Åfjorden (63° 56' N, 10° 11' E) and two in Inner and Outer Koet, respectively (63° 49' N, 9° 42' and 47' E). Four seston variables were used as alternative input values in a Dynamic Energy Budget (DEB) model to compare their suitability as food proxies for predicting mussel growth: 1; total particulate matter (TPM), 2; particulate organic matter (POM), 3; organic content (OC) and 4; chlorophyll a (chl a). Mean TPM and POM measured 6.1 and 1.9 mg L - 1 in Åfjorden, 10.3 and 4.2 mg L - 1 in Inner Koet, and 10.5 and 4.6 mg L - 1 in Outer Koet, respectively, resulting in a mean OC of 32, 41 and 44% in Åfjorden and Inner and Outer Koet, respectively. Mean chl a measured 1.6 μg L - 1 in Åfjorden, 3.1 μg L - 1 in Inner Koet, and 1.6 μg L - 1 in Outer Koet. Average length growth was 0.20% day - 1 in medium sized mussels (24-36 mm) in Åfjorden and 0.08% day - 1 in large mussels (40-55 mm) in Inner and Outer Koet. Mean standardized soft tissue dry weight ranged between 250 and 390 mg in Åfjorden, 600 and 1175 in Inner Koet, and 600 and 960 mg in Outer Koet, and showed a seasonal pattern independent of growth in length with scattered spawnings. The model showed the best match for a single criterion for growth in both length and soft tissue dry weight for different food proxies depending on location. TPM gave the best match in Åfjorden, while chl a and POM gave the best match in Inner and Outer Koet, respectively. For Åfjorden, growth in length decreased markedly at the end of the sampling period, and this decrease was not reproduced by the model for any of the food proxies. For Inner and Outer Koet, agreement between measured and modeled length was quite good for the optimal choices of food proxy, with clear variations between the proxies for both farms. The model fit the observed soft tissue dry weight well in Åfjorden and Outer Koet, while underestimating it in Inner Koet. The differences in fit between proxies were minor for Åfjorden and Outer Koet, while OC gave the best fit and chl a the poorest fit for Inner Koet. The results indicate that different food sources have different impact on growth at different locations. DEB modeling is a useful tool in comparing which proxies give the most relevant information.

A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria.

PubMed

Gornicka, Agnieszka; Bragoszewski, Piotr; Chroscicki, Piotr; Wenz, Lena-Sophie; Schulz, Christian; Rehling, Peter; Chacinska, Agnieszka

2014-12-15

Mitochondrial proteins are synthesized on cytosolic ribosomes and imported into mitochondria with the help of protein translocases. For the majority of precursor proteins, the role of the translocase of the outer membrane (TOM) and mechanisms of their transport across the outer mitochondrial membrane are well recognized. However, little is known about the mode of membrane translocation for proteins that are targeted to the intermembrane space via the redox-driven mitochondrial intermembrane space import and assembly (MIA) pathway. On the basis of the results obtained from an in organello competition import assay, we hypothesized that MIA-dependent precursor proteins use an alternative pathway to cross the outer mitochondrial membrane. Here we demonstrate that this alternative pathway involves the protein channel formed by Tom40. We sought a translocation intermediate by expressing tagged versions of MIA-dependent proteins in vivo. We identified a transient interaction between our model substrates and Tom40. Of interest, outer membrane translocation did not directly involve other core components of the TOM complex, including Tom22. Thus MIA-dependent proteins take another route across the outer mitochondrial membrane that involves Tom40 in a form that is different from the canonical TOM complex. © 2014 Gornicka et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

The truth about laser fiber diameters.

PubMed

Kronenberg, Peter; Traxer, Olivier

2014-12-01

To measure the various diameters of laser fibers from various manufacturers and compare them with the advertised diameter. Fourteen different unused laser fibers from 6 leading manufacturers with advertised diameters of 200, 270, 272, 273, 365, and 400 μm were measured by light microscopy. The outer diameter (including the fiber coating, cladding, and core), cladding diameter (including the cladding and the fiber core), and core diameter were measured. Industry representatives of the manufacturers were interviewed about the diameter of their fibers. For all fibers, the outer and cladding diameters differed significantly from the advertised diameter (P <.00001). The outer diameter, which is of most practical relevance for urologists, exhibited a median increase of 87.3% (range, 50.7%-116.7%). The outer, cladding, and core diameters of fibers with equivalent advertised diameters differed by up to 180, 100, and 78 μm, respectively. Some 200-μm fibers had larger outer diameters than the 270- to 273-μm fibers. All packaging material and all laser fibers lacked clear and precise fiber diameter information labels. Of 12 representatives interviewed, 8, 3, and 1 considered the advertised diameter to be the outer, the cladding, and the core diameter, respectively. Representatives within the same company frequently gave different answers. This study suggests that, at present, there is a lack of uniformity between laser fiber manufacturers, and most of the information conveyed to urologists regarding laser fiber diameter may be incorrect. Because fibers larger than the advertised laser fibers are known to influence key interventional parameters, this misinformation can have surgical repercussions. Copyright © 2014 Elsevier Inc. All rights reserved.

Systems to facilitate reducing flashback/flame holding in combustion systems

DOEpatents

Lacy, Benjamin Paul [Greer, SC; Kraemer, Gilbert Otto [Greer, SC; Varatharajan, Balachandar [Clifton Park, NY; Yilmaz, Ertan [Albany, NY; Zuo, Baifang [Simpsonville, SC

2012-02-21

A method for assembling a premixing injector is provided. The method includes providing a centerbody including a center axis and a radially outer surface, and providing an inlet flow conditioner. The inlet flow conditioner includes a radially outer wall, a radially inner wall, and an end wall coupled substantially perpendicularly between the outer wall and the inner wall. Each of the outer wall and the end wall include a plurality of openings defined therein. The outer wall, the inner wall, and the end wall define a first passage therebetween. The method also includes coupling the inlet flow conditioner to the centerbody such that the inlet flow conditioner substantially circumscribes the centerbody, such that the inner wall is substantially parallel to the centerbody outer surface, and such that a second passage is defined between the centerbody outer surface and the inner wall.

Simulation of a Dispersive Tsunami due to the 2016 El Salvador-Nicaragua Outer-Rise Earthquake (M w 6.9)

NASA Astrophysics Data System (ADS)

Tanioka, Yuichiro; Ramirez, Amilcar Geovanny Cabrera; Yamanaka, Yusuke

2018-01-01

The 2016 El Salvador-Nicaragua outer-rise earthquake (M w 6.9) generated a small tsunami observed at the ocean bottom pressure sensor, DART 32411, in the Pacific Ocean off Central America. The dispersive observed tsunami is well simulated using the linear Boussinesq equations. From the dispersive character of tsunami waveform, the fault length and width of the outer-rise event is estimated to be 30 and 15 km, respectively. The estimated seismic moment of 3.16 × 1019 Nm is the same as the estimation in the Global CMT catalog. The dispersive character of the tsunami in the deep ocean caused by the 2016 outer-rise El Salvador-Nicaragua earthquake could constrain the fault size and the slip amount or the seismic moment of the event.

Saturn's outer magnetosphere

NASA Technical Reports Server (NTRS)

Schardt, A. W.; Behannon, K. W.; Carbary, J. F.; Eviatar, A.; Lepping, R. P.; Siscoe, G. L.

1983-01-01

Similarities between the Saturnian and terrestrial outer magnetosphere are examined. Saturn, like Earth, has a fully developed magnetic tail, 80 to 100 RS in diameter. One major difference between the two outer magnetospheres is the hydrogen and nitrogen torus produced by Titan. This plasma is, in general, convected in the corotation direction at nearly the rigid corotation speed. Energies of magnetospheric particles extend to above 500 keV. In contrast, interplanetary protons and ions above 2 MeV have free access to the outer magnetosphere to distances well below the Stormer cutoff. This access presumably occurs through the magnetotail. In addition to the H+, H2+, and H3+ ions primarily of local origin, energetic He, C, N, and O ions are found with solar composition. Their flux can be substantially enhanced over that of interplanetary ions at energies of 0.2 to 0.4 MeV/nuc.

Operating characteristics of a three-piece-inner-ring large-bore roller bearing to speeds of 3 million DN

NASA Technical Reports Server (NTRS)

Schuller, F. T.

1984-01-01

A 118 mm bore roller bearing with a three piece inner ring ran successfully at 300,000 DN for 20 hr. Provisions were made for lubrication and cooling through the inner ring. In some tests the outer ring was also cooled. Power loss within the bearing increased with both speed and total oil flow rate to the inner ring. Outer ring temperature decreased by as much as 22 K (40 F) when outer ring cooling was employed whereas inner ring temperature remained essentially constant. Cage slip was greatly reduced or even eliminated by using a bearing with a very tight clearance at operating speed. A three piece inner ring bearing had higher inner ring temperatures and less temperature difference between the inner and outer rings than a conventional one piece inner ring bearing.

Simulation of a Dispersive Tsunami due to the 2016 El Salvador-Nicaragua Outer-Rise Earthquake ( M w 6.9)

NASA Astrophysics Data System (ADS)

Tanioka, Yuichiro; Ramirez, Amilcar Geovanny Cabrera; Yamanaka, Yusuke

2018-04-01

The 2016 El Salvador-Nicaragua outer-rise earthquake ( M w 6.9) generated a small tsunami observed at the ocean bottom pressure sensor, DART 32411, in the Pacific Ocean off Central America. The dispersive observed tsunami is well simulated using the linear Boussinesq equations. From the dispersive character of tsunami waveform, the fault length and width of the outer-rise event is estimated to be 30 and 15 km, respectively. The estimated seismic moment of 3.16 × 1019 Nm is the same as the estimation in the Global CMT catalog. The dispersive character of the tsunami in the deep ocean caused by the 2016 outer-rise El Salvador-Nicaragua earthquake could constrain the fault size and the slip amount or the seismic moment of the event.

Gene cloning and prokaryotic expression of recombinant outer membrane protein from Vibrio parahaemolyticus

NASA Astrophysics Data System (ADS)

Yuan, Ye; Wang, Xiuli; Guo, Sheping; Qiu, Xuemei

2011-06-01

Gram-negative Vibrio parahaemolyticus is a common pathogen in humans and marine animals. The outer membrane protein of bacteria plays an important role in the infection and pathogenicity to the host. Thus, the outer membrane proteins are an ideal target for vaccines. We amplified a complete outer membrane protein gene (ompW) from V. parahaemolyticus ATCC 17802. We then cloned and expressed the gene into Escherichia coli BL21 (DE3) cells. The gene coded for a protein that was 42.78 kDa. We purified the protein using Ni-NTA affinity chromatography and Anti-His antibody Western blotting, respectively. Our results provide a basis for future application of the OmpW protein as a vaccine candidate against infection by V. parahaemolyticus. In addition, the purified OmpW protein can be used for further functional and structural studies.

2,4-Dichlorophenoxyacetic Acid Inhibits the Outer Membrane NADH Dehydrogenase of Plant Mitochondria 1

PubMed Central

Mannella, Carmen A.; Bonner, Walter D.

1978-01-01

The NADH dehydrogenase of potato (Solanum tuberosum) and mung bean (Phaseolus aureus) outer mitochondrial membranes is specifically inhibited by both 2,4-dichlorophenoxyacetic and 2,4,5-trichlorophenoxyacetic acids but not by the natural auxin indole-3-acetic acid. PMID:16660539

49 CFR 178.707 - Standards for composite IBCs.

Code of Federal Regulations, 2013 CFR

2013-10-01

... designed to bear the entire stacking load. The inner receptacle and outer packaging form an integral... outer packaging. (2) A composite IBC with a fully enclosing outer packaging must be designed to permit assessment of the integrity of the inner container following the leakproofness and hydraulic tests. The outer...

Zone heated diesel particulate filter electrical connection

DOEpatents

Gonze, Eugene V.; Paratore, Jr., Michael J.

2010-03-30

An electrical connection system for a particulate filter is provided. The system includes: a particulate filter (PF) disposed within an outer shell wherein the PF is segmented into a plurality of heating zones; an outer mat disposed between the particulate filter and the outer shell; an electrical connector coupled to the outer shell of the PF; and a plurality of printed circuit connections that extend along the outer surface of the PF from the electrical connector to the plurality of heating zones.

Redundant Bearing Assembly

NASA Technical Reports Server (NTRS)

Wright, Jay M.

1995-01-01

Proposed redundant bearing assembly consists of two modified ball or roller bearings, one held by other. Outer race of inner bearing press-fit into inner race of outer bearing. Within each bearing, side walls of inner and outer races extended radially toward each other leaving only small gap. In assembly, one bearing continues to allow free rotation when other fails. Bearing wear monitored by examination of gaps between races. In alternative design, inner race of outer bearing and outer race of inner bearing manufactured as single piece.

Particle trap with dielectric barrier for use in gas insulated transmission lines

DOEpatents

Dale, S.J.

1982-06-15

A gas-insulated transmission line includes an outer sheath, an inner conductor within the outer sheath, insulating supports supporting the inner conductor within the outer sheath, and an insulating gas electrically insulating the inner conductor from the outer sheath. An apertured particle trapping electrode is disposed within the outer sheath, and the electrode has a pair of dielectric members secured at each longitudinal end thereof, with the dielectric members extending outwardly from the apertured electrode. 7 figs.

Annular fuel and air co-flow premixer

DOEpatents

Stevenson, Christian Xavier; Melton, Patrick Benedict; York, William David

2013-10-15

Disclosed is a premixer for a combustor including an annular outer shell and an annular inner shell. The inner shell defines an inner flow channel inside of the inner shell and is located to define an outer flow channel between the outer shell and the inner shell. A fuel discharge annulus is located between the outer flow channel and the inner flow channel and is configured to inject a fuel flow into a mixing area in a direction substantially parallel to an outer airflow through the outer flow channel and an inner flow through the inner flow channel. Further disclosed are a combustor including a plurality of premixers and a method of premixing air and fuel in a combustor.

Article, component, and method of forming an article

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lacy, Benjamin Paul; Itzel, Gary Michael; Kottilingam, Srikanth Chandrudu

An article and method of forming an article are provided. The article includes a body portion separating an inner region and an outer region, an aperture in the body portion, the aperture fluidly connecting the inner region to the outer region, and a conduit extending from an outer surface of the body portion at the aperture and being arranged and disposed to controllably direct fluid from the inner region to the outer region. The method includes providing a body portion separating an inner region and an outer region, providing an aperture in the body portion, and forming a conduit overmore » the aperture, the conduit extending from an outer surface of the body portion and being arranged and disposed to controllably direct fluid from the inner region to the outer region. The article is arranged and disposed for insertion within a hot gas path component.« less

Swirling structure for mixing two concentric fluid flows at nozzle outlet

DOEpatents

Mensink, Daniel L.

1993-01-01

A nozzle device for causing two fluids to mix together. In particular, a spray nozzle comprise two hollow, concentric housings, an inner housing and an outer housing. The inner housing has a channel formed therethrough for a first fluid. Its outer surface cooperates with the interior surface of the outer housing to define the second channel for a second fluid. The outer surface of the inner housing and the inner surface of the outer housing each carry a plurality of vanes that interleave but do not touch, each vane of one housing being between two vanes of the other housing. The vanes are curved and the inner surface of the outer housing and the outer surface of the inner housing converge to narrow the second channel. The shape of second channel results in a swirling, accelerating second fluid that will impact the first fluid just past the end of the nozzle where mixing will take place.

Light-Induced Thickening of Photoreceptor Outer Segment Layer Detected by Ultra-High Resolution OCT Imaging.

PubMed

Li, Yichao; Fariss, Robert N; Qian, Jennifer W; Cohen, Ethan D; Qian, Haohua

2016-07-01

We examined if light induces changes in the retinal structure that can be observed using optical coherence tomography (OCT). Normal C57BL/6J mice (age 3-6 months) adapted to either room light (15 minutes to ∼5 hours, 50-500 lux) or darkness (overnight) were imaged using a Bioptigen UHR-OCT system. Confocal histologic images were obtained from mice killed under light- or dark-adapted conditions. The OCT image of eyes adapted to room light exhibited significant increases (6.1 ± 0.8 μm, n = 13) in total retina thickness compared to the same eyes after overnight dark adaptation. These light-adapted retinal thickness changes occurred mainly in the outer retina, with the development of a hyporeflective band between the RPE and photoreceptor-tip layers. Histologic analysis revealed a light-evoked elongation between the outer limiting membrane and Bruch's membrane from 45.8 ± 1.7 μm in the dark (n = 5) to 52.1 ± 3.7 μm (n = 5) in the light. Light-adapted retinas showed an increase of actin staining in RPE apical microvilli at the same location as the hyporeflective band observed in OCT images. Elongation of the outer retina could be detected even with brief light exposures, increasing 2.1 ± 0.3 μm after 15 minutes (n = 9), and 4.1 ± 1.0 μm after 2 hours (n = 6). Conversely, dark-adaptation caused outer retinal shortening of 1.4 ± 0.4 μm (n = 7) and 3.0 ± 0.5 μm (n = 8) after 15 minutes and 2 hours, respectively. Light-adaption induces an increase in the thickness of the outer retina and the appearance of a hyporeflective band in the OCT image. This is consistent with previous reports of light-induced fluid accumulation in the subretinal space.

49 CFR 179.220 - General specifications applicable to nonpressure tank car tanks consisting of an inner container...

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false General specifications applicable to nonpressure tank car tanks consisting of an inner container supported within an outer shell (class DOT-115). 179... within an outer shell (class DOT-115). ...

77 FR 19321 - Geological and Geophysical Exploration on the Atlantic Outer Continental Shelf (OCS)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-30

... by BOEM: (1) Oil and gas exploration and development; (2) renewable energy; and (3) marine minerals... DEPARTMENT OF THE INTERIOR Bureau of Ocean Energy Management Geological and Geophysical Exploration on the Atlantic Outer Continental Shelf (OCS) AGENCY: Bureau of Ocean Energy Management (BOEM...

76 FR 7518 - Outer Continental Shelf Air Regulations Consistency Update for Alaska

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-10

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 55 [EPA-R10-OAR-2011-0045; FRL-9265-3] Outer Continental Shelf Air Regulations Consistency Update for Alaska AGENCY: Environmental Protection Agency (``EPA... Greaves, Federal and Delegated Air Programs Unit, U.S. Environmental Protection Agency, Region 10, 1200...

3-D orbital evolution model of outer asteroid belt

NASA Technical Reports Server (NTRS)

Solovaya, Nina A.; Gerasimov, Igor A.; Pittich, Eduard M.

1992-01-01

The evolution of minor planets in the outer part of the asteroid belt is considered. In the framework of the semi-averaged elliptic restricted three-dimensional three-body model, the boundary of regions of the Hill's stability is found. As was shown in our work, the Jacobian integral exists.

49 CFR Appendix D to Part 178 - Thermal Resistance Test

Code of Federal Regulations, 2013 CFR

2013-10-01

... large enough in size to fully house the test outer package without clearance problems. The test oven....3Instrumentation. A calibrated recording device or a computerized data acquisition system with an appropriate range... Configuration. Each outer package material type and design must be tested, including any features such as...

49 CFR Appendix D to Part 178 - Thermal Resistance Test

Code of Federal Regulations, 2014 CFR

2014-10-01

... large enough in size to fully house the test outer package without clearance problems. The test oven....3Instrumentation. A calibrated recording device or a computerized data acquisition system with an appropriate range... Configuration. Each outer package material type and design must be tested, including any features such as...

49 CFR Appendix D to Part 178 - Thermal Resistance Test

Code of Federal Regulations, 2011 CFR

2011-10-01

... large enough in size to fully house the test outer package without clearance problems. The test oven....3Instrumentation. A calibrated recording device or a computerized data acquisition system with an appropriate range... Configuration. Each outer package material type and design must be tested, including any features such as...

49 CFR Appendix D to Part 178 - Thermal Resistance Test

Code of Federal Regulations, 2012 CFR

2012-10-01

... large enough in size to fully house the test outer package without clearance problems. The test oven....3Instrumentation. A calibrated recording device or a computerized data acquisition system with an appropriate range... Configuration. Each outer package material type and design must be tested, including any features such as...

Implementation of an Outer Can Welding System for Savannah River Site FB-Line

DOE Office of Scientific and Technical Information (OSTI.GOV)

Howard, S.R.

2003-03-27

This paper details three phases of testing to confirm use of a Gas Tungsten Arc (GTA) system for closure welding the 3013 outer container used for stabilization/storage of plutonium metals and oxides. The outer container/lid closure joint was originally designed for laser welding, but for this application, the gas tungsten arc (GTA) welding process has been adapted. The testing progressed in three phases: (1) system checkout to evaluate system components for operational readiness, (2) troubleshooting to evaluate high weld failure rates and develop corrective techniques, and (3) pre-installation acceptance testing.

78 FR 29091 - Safety Zone; Outer Banks Bluegrass Festival; Shallowbag Bay, Manteo, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-17

...-AA00 Safety Zone; Outer Banks Bluegrass Festival; Shallowbag Bay, Manteo, NC AGENCY: Coast Guard, DHS... the Outer Banks Bluegrass Festival. This action is necessary to protect the life and property of the... vessels from a portion of Shallowbag Bay River during the Outer Banks Bluegrass Festival Fireworks display...

77 FR 58794 - Airworthiness Directives; Bell Helicopter Textron, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-24

... swashplate outer ring assemblies (outer ring). This AD would establish a lower life limit on certain outer rings, requiring a revision of the retirement life on the components' history card or equivalent record.... The outer ring previously had a life limit of 10,000 hours TIS, but Bell has recommended reducing the...

46 CFR 154.170 - Outer hull steel plating.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Structure § 154.170 Outer hull steel plating. (a) Except as required in paragraph (b) of this section, the outer hull steel plating, including the shell and deck plating must meet the material standards of the... 46 Shipping 5 2014-10-01 2014-10-01 false Outer hull steel plating. 154.170 Section 154.170...

46 CFR 154.170 - Outer hull steel plating.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Structure § 154.170 Outer hull steel plating. (a) Except as required in paragraph (b) of this section, the outer hull steel plating, including the shell and deck plating must meet the material standards of the... 46 Shipping 5 2012-10-01 2012-10-01 false Outer hull steel plating. 154.170 Section 154.170...

46 CFR 154.170 - Outer hull steel plating.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Structure § 154.170 Outer hull steel plating. (a) Except as required in paragraph (b) of this section, the outer hull steel plating, including the shell and deck plating must meet the material standards of the... 46 Shipping 5 2013-10-01 2013-10-01 false Outer hull steel plating. 154.170 Section 154.170...

Wing kinematics measurement and aerodynamics of a dragonfly in turning flight.

PubMed

Li, Chengyu; Dong, Haibo

2017-02-03

This study integrates high-speed photogrammetry, 3D surface reconstruction, and computational fluid dynamics to explore a dragonfly (Erythemis Simplicicollis) in free flight. Asymmetric wing kinematics and the associated aerodynamic characteristics of a turning dragonfly are analyzed in detail. Quantitative measurements of wing kinematics show that compared to the outer wings, the inner wings sweep more slowly with a higher angle of attack during the downstroke, whereas they flap faster with a lower angle of attack during the upstroke. The inner-outer asymmetries of wing deviations result in an oval wingtip trajectory for the inner wings and a figure-eight wingtip trajectory for the outer wings. Unsteady aerodynamics calculations indicate significantly asymmetrical force production between the inner and outer wings, especially for the forewings. Specifically, the magnitude of the drag force on the inner forewing is approximately 2.8 times greater than that on the outer forewing during the downstroke. In the upstroke, the outer forewing generates approximately 1.9 times greater peak thrust than the inner forewing. To keep the body aloft, the forewings contribute approximately 64% of the total lift, whereas the hindwings provide 36%. The effect of forewing-hindwing interaction on the aerodynamic performance is also examined. It is found that the hindwings can benefit from this interaction by decreasing power consumption by 13% without sacrificing force generation.

Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles.

PubMed

Kahnt, Jörg; Aguiluz, Kryssia; Koch, Jürgen; Treuner-Lange, Anke; Konovalova, Anna; Huntley, Stuart; Hoppert, Michael; Søgaard-Andersen, Lotte; Hedderich, Reiner

2010-10-01

Social behavior in the bacterium Myxococcus xanthus relies on contact-dependent activities involving cell-cell and cell-substratum interactions. To identify outer membrane proteins that have a role in these activities, we profiled the outer membrane proteome of growing and starving cells using two strategies. First, outer membrane proteins were enriched by biotinylation of intact cells using the reagent NHS (N-hydroxysuccinimide)-PEO(12) (polyethylene oxide)-biotin with subsequent membrane solubilization and affinity chromatography. Second, the proteome of outer membrane vesicles (OMV) was determined. Comparisons of detected proteins show that these methods have different detection profiles and together provide a comprehensive view of the outer membrane proteome. From 362 proteins identified, 274 (76%) were cell envelope proteins including 64 integral outer membrane proteins and 85 lipoproteins. The majority of these proteins were of unknown function. Among integral outer membrane proteins with homologues of known function, TonB-dependent transporters comprise the largest group. Our data suggest novel functions for these transporters. Among lipoproteins with homologues of known function, proteins with hydrolytic functions comprise the largest group. The luminal load of OMV was enriched for proteins with hydrolytic functions. Our data suggest that OMV have functions in predation and possibly in transfer of intercellular signaling molecules between cells.

Turbine nozzle/nozzle support structure

DOEpatents

Boyd, Gary L.; Shaffer, James E.

1997-01-01

An axial flow turbine's nozzle/nozzle support structure having a cantilevered nozzle outer structure including an outer shroud and airfoil vanes extending radially inwardly therefrom, an inner shroud radially adjacent the inner end of the airfoil vanes and cooperatively disposed relative to the outer shroud to provide an annular fluid flow path, an inner and an outer support ring respectively arranged radially inside the inner shroud and axially adjacent a portion of the outer shroud, and pins extending through such portion and into the outer support ring. The inner support ring or inner shroud has a groove therein bounded by end walls for receiving and being axially abuttable with a locating projection from the adjacent airfoil vane, inner shroud, or inner support ring. The nozzle outer structure may comprise segments each of which has a single protrusion which is axially engageable with the outer support ring or, alternatively, a first and second protrusion which are arcuately and axially separated and which include axial openings therein whereby first and second protrusions on respective, arcuately adjacent nozzle segments have axial openings therein which are alignable with connector openings in the outer support ring and within each of such aligned openings a pin is receivable. The inner shroud may, likewise, comprise segments which, when assembled in operating configuration, have a 360 degree expanse.

Turbine nozzle/nozzle support structure

DOEpatents

Boyd, G.L.; Shaffer, J.E.

1997-01-07

An axial flow turbine`s nozzle/nozzle support structure is described having a cantilevered nozzle outer structure including an outer shroud and airfoil vanes extending radially inwardly therefrom, an inner shroud radially adjacent the inner end of the airfoil vanes and cooperatively disposed relative to the outer shroud to provide an annular fluid flow path, an inner and an outer support ring respectively arranged radially inside the inner shroud and axially adjacent a portion of the outer shroud, and pins extending through such portion and into the outer support ring. The inner support ring or inner shroud has a groove therein bounded by end walls for receiving and being axially abuttable with a locating projection from the adjacent airfoil vane, inner shroud, or inner support ring. The nozzle outer structure may comprise segments each of which has a single protrusion which is axially engageable with the outer support ring or, alternatively, a first and second protrusion which are arcuately and axially separated and which include axial openings therein whereby first and second protrusions on respective, arcuately adjacent nozzle segments have axial openings therein which are alignable with connector openings in the outer support ring and within each of such aligned openings a pin is receivable. The inner shroud may, likewise, comprise segments which, when assembled in operating configuration, have a 360 degree expanse. 6 figs.

Turbine nozzle/nozzle support structure

DOEpatents

Boyd, Gary L.; Shaffer, James E.

1996-01-01

An axial flow turbine's nozzle/nozzle support structure having a cantilevered nozzle outer structure including an outer shroud and airfoil vanes extending radially inwardly therefrom, an inner shroud radially adjacent the inner end of the airfoil vanes and cooperatively disposed relative to the outer shroud to provide an annular fluid flow path, an inner and an outer support ring respectively arranged radially inside the inner shroud and axially adjacent a portion of the outer shroud, and pins extending through such portion and into the outer support ring. The inner support ring or inner shroud has a groove therein bounded by end walls for receiving and being axially abuttable with a locating projection from the adjacent airfoil vane, inner shroud, or inner support ring. The nozzle outer structure may comprise segments each of which has a single protrusion which is axially engageable with the outer support ring or, alternatively, a first and second protrusion which are arcuately and axially separated and which include axial openings therein whereby first and second protrusions on respective, arcuately adjacent nozzle segments have axial openings therein which are alignable with connector openings in the outer support ring and within each of such aligned openings a pin is receivable. The inner shroud may, likewise, comprise segments which, when assembled in operating configuration, have a 360 degree expanse.

Turbine nozzle/nozzle support structure

DOEpatents

Boyd, G.L.; Shaffer, J.E.

1996-09-10

An axial flow turbine`s nozzle/nozzle support structure is described having a cantilevered nozzle outer structure including an outer shroud and airfoil vanes extending radially inwardly therefrom, an inner shroud radially adjacent the inner end of the airfoil vanes and cooperatively disposed relative to the outer shroud to provide an annular fluid flow path, an inner and an outer support ring respectively arranged radially inside the inner shroud and axially adjacent a portion of the outer shroud, and pins extending through such portion and into the outer support ring. The inner support ring or inner shroud has a groove therein bounded by end walls for receiving and being axially abuttable with a locating projection from the adjacent airfoil vane, inner shroud, or inner support ring. The nozzle outer structure may comprise segments each of which has a single protrusion which is axially engageable with the outer support ring or, alternatively, a first and second protrusion which are arcuately and axially separated and which include axial openings therein whereby first and second protrusions on respective, arcuately adjacent nozzle segments have axial openings therein which are alignable with connector openings in the outer support ring and within each of such aligned openings a pin is receivable. The inner shroud may, likewise, comprise segments which, when assembled in operating configuration, have a 360 degree expanse. 6 figs.

Turbine nozzle/nozzle support structure

DOEpatents

Boyd, Gary L.; Shaffer, James E.

1995-01-01

An axial flow turbine's nozzle/nozzle support structure having a cantilevered nozzle outer structure including an outer shroud and airfoil vanes extending radially inwardly therefrom, an inner shroud radially adjacent the inner end of the airfoil vanes and cooperatively disposed relative to the outer shroud to provide an annular fluid flow path, an inner and an outer support ring respectively arranged radially inside the inner shroud and axially adjacent a portion of the outer shroud, and pins extending through such portion and into the outer support ring. The inner support ring or inner shroud has a groove therein bounded by end walls for receiving and being axially abuttable with a locating projection from the adjacent airfoil vane, inner shroud, or inner support ring. The nozzle outer structure may comprise segments each of which has a single protrusion which is axially engageable with the outer support ring or, alternatively, a first and second protrusion which are arcuately and axially separated and which include axial openings therein whereby first and second protrusions on respective, arcuately adjacent nozzle segments have axial openings therein which are alignable with connector openings in the outer support ring and within each of such aligned openings a pin is receivable. The inner shroud may, likewise, comprise segments which, when assembled in operating configuration, have a 360 degree expanse.

Turbine nozzle/nozzle support structure

DOEpatents

Boyd, G.L.; Shaffer, J.E.

1995-08-15

An axial flow turbine`s nozzle/nozzle support structure is described having a cantilevered nozzle outer structure including an outer shroud and airfoil vanes extending radially inwardly therefrom, an inner shroud radially adjacent the inner end of the airfoil vanes and cooperatively disposed relative to the outer shroud to provide an annular fluid flow path, an inner and an outer support ring respectively arranged radially inside the inner shroud and axially adjacent a portion of the outer shroud, and pins extending through such portion and into the outer support ring. The inner support ring or inner shroud has a groove therein bounded by end walls for receiving and being axially abuttable with a locating projection from the adjacent airfoil vane, inner shroud, or inner support ring. The nozzle outer structure may comprise segments each of which has a single protrusion which is axially engageable with the outer support ring or, alternatively, a first and second protrusion which are arcuately and axially separated and which include axial openings therein whereby first and second protrusions on respective, arcuately adjacent nozzle segments have axial openings therein which are alignable with connector openings in the outer support ring and within each of such aligned openings a pin is receivable. The inner shroud may, likewise, comprise segments which, when assembled in operating configuration, have a 360 degree expanse. 6 figs.

Formation of the outer layer of the Dictyostelium spore coat depends on the inner-layer protein SP85/PsB.

PubMed

Metcalf, Talibah; Kelley, Karen; Erdos, Gregory W; Kaplan, Lee; West, Christopher M

2003-02-01

The Dictyostelium spore is surrounded by a 220 microm thick trilaminar coat that consists of inner and outer electron-dense layers surrounding a central region of cellulose microfibrils. In previous studies, a mutant strain (TL56) lacking three proteins associated with the outer layer exhibited increased permeability to macromolecular tracers, suggesting that this layer contributes to the coat permeability barrier. Electron microscopy now shows that the outer layer is incomplete in the coats of this mutant and consists of a residual regular array of punctate electron densities. The outer layer is also incomplete in a mutant lacking a cellulose-binding protein associated with the inner layer, and these coats are deficient in an outer-layer protein and another coat protein. To examine the mechanism by which this inner-layer protein, SP85, contributes to outer-layer formation, various domain fragments were overexpressed in forming spores. Most of these exert dominant negative effects similar to the deletion of outer-layer proteins, but one construct, consisting of a fusion of the N-terminal and Cys-rich C1 domain, induces a dense mat of novel filaments at the surface of the outer layer. Biochemical studies show that the C1 domain binds cellulose, and a combination of site-directed mutations that inhibits its cellulose-binding activity suppresses outer-layer filament induction. The results suggest that, in addition to a previously described early role in regulating cellulose synthesis, SP85 subsequently contributes a cross-bridging function between cellulose and other coat proteins to organize previously unrecognized structural elements in the outer layer of the coat.

Estimation of outer-middle ear transmission using DPOAEs and fractional-order modeling of human middle ear

NASA Astrophysics Data System (ADS)

Naghibolhosseini, Maryam

Our ability to hear depends primarily on sound waves traveling through the outer and middle ear toward the inner ear. Hence, the characteristics of the outer and middle ear affect sound transmission to/from the inner ear. The role of the middle and outer ear in sound transmission is particularly important for otoacoustic emissions (OAEs), which are sound signals generated in a healthy cochlea, and recorded by a sensitive microphone placed in the ear canal. OAEs are used to evaluate the health and function of the cochlea; however, they are also affected by outer and middle ear characteristics. To better assess cochlear health using OAEs, it is critical to quantify the impact of the outer and middle ear on sound transmission. The reported research introduces a noninvasive approach to estimate outer-middle ear transmission using distortion product otoacoustic emissions (DPOAEs). In addition, the role of the outer and middle ear on sound transmission was investigated by developing a physical/mathematical model, which employed fractional-order lumped elements to include the viscoelastic characteristics of biological tissues. Impedance estimations from wideband refectance measurements were used for parameter fitting of the model. The model was validated comparing its estimates of the outer-middle ear sound transmission with those given by DPOAEs. The outer-middle ear transmission by the model was defined as the sum of forward and reverse outer-middle ear transmissions. To estimate the reverse transmission by the model, the probe-microphone impedance was calculated through estimating the Thevenin-equivalent circuit of the probe-microphone. The Thevenin-equivalent circuit was calculated using measurements in a number of test cavities. Such modeling enhances our understanding of the roles of different parts of the outer and middle ear and how they work together to determine their function. In addition, the model would be potentially helpful in diagnosing pathologies of cochlear or middle ear origin.

The membrane current of single rod outer segments.

PubMed

Baylor, D A; Lamb, T D; Yau, K W

1979-03-01

1. Outer segments of individual rods in the retina of the toad, Bufo marinus, were drawn into a glass pipette to record the membrane current. 2. Light flashes evoked transient outward currents. The peak response amplitude was related to flash intensity by a Michaelis equation with half-saturating intensity about 1 photon mum-2. 3. The saturating response amplitude ranged up to 27 pA and corresponded closely to complete suppression of the steady inward current present in darkness. 4. For a given cell the saturating response amplitude varied linearly with the length of outer segment within the pipette. This is consistent with a uniform density of light-sensitive channels and negligible gradient of membrane potential along the outer segment. 5. Responses to bright flashes never showed the relaxation from an initial peak seen previously in intracellular voltage recordings, suggesting that the conductance change responsible for the relaxation does not occur in the outer segment. 6. Responses to local illumination of only the recorded outer segment were very similar to those obtained with diffuse light at the same intensity, indicating that peripheral rods made little contribution to the responses. 7. The spectral sensitivity of 'red' rods was consistent with a retinal1-based pigment with lambda max = 498 +/- 2 nm. 8. The kinetics of the response were consistent with four stages of delay affecting action of the internal transmitter. Responses were faster at the basal end of the outer segment than at the distal tip. 9. Background light reduced the sensitivity to a superposed dim test flash and shortened the time course of the response, indicating that adapting light modifies the kinetics and gain of the transduction mechanism within the outer segment. 10. Responses to dim lights exhibited pronounced fluctuations which are attributed in the succeeding paper (Baylor, Lamb & Yau, 1979) to the quantal nature of light.

The outer magnetosphere. [composition and comparison with earth

NASA Technical Reports Server (NTRS)

Schardt, A. W.; Behannon, K. W.; Lepping, R. P.; Carbary, J. F.; Eviatar, A.; Siscoe, G. L.

1984-01-01

Similarities between the Saturnian and terrestrial outer magnetosphere are examined. Saturn, like earth, has a fully developed magnetic tail, 80 to 100 RS in diameter. One major difference between the two outer magnetospheres is the hydrogen and nitrogen torus produced by Titan. This plasma is, in general, convected in the corotation direction at nearly the rigid corotation speed. Energies of magnetospheric particles extend to above 500 keV. In contrast, interplanetary protons and ions above 2 MeV have free access to the outer magnetosphere to distances well below the Stormer cutoff. This access presumably occurs through the magnetotail. In addition to the H+, H2+, and H3+ ions primarily of local origin, energetic He, C, N, and O ions are found with solar composition. Their flux can be substantially enhanced over that of interplanetary ions at energies of 0.2 to 0.4 MeV/nuc.

Structure of Rotavirus Outer-Layer Protein VP7 Bound with a Neutralizing Fab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aoki, Scott T.; Settembre, Ethan C.; Trask, Shane D.

2009-06-17

Rotavirus outer-layer protein VP7 is a principal target of protective antibodies. Removal of free calcium ions (Ca{sup 2+}) dissociates VP7 trimers into monomers, releasing VP7 from the virion, and initiates penetration-inducing conformational changes in the other outer-layer protein, VP4. We report the crystal structure at 3.4 angstrom resolution of VP7 bound with the Fab fragment of a neutralizing monoclonal antibody. The Fab binds across the outer surface of the intersubunit contact, which contains two Ca{sup 2+} sites. Mutations that escape neutralization by other antibodies suggest that the same region bears the epitopes of most neutralizing antibodies. The monovalent Fab ismore » sufficient to neutralize infectivity. We propose that neutralizing antibodies against VP7 act by stabilizing the trimer, thereby inhibiting the uncoating trigger for VP4 rearrangement. A disulfide-linked trimer is a potential subunit immunogen.« less

75 FR 67454 - Allowance for Private Purchase of an Outer Burial Receptacle in Lieu of a Government-Furnished...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-02

... DEPARTMENT OF VETERANS AFFAIRS Allowance for Private Purchase of an Outer Burial Receptacle in... Department of Veterans Affairs (VA) to provide a monetary allowance towards the private purchase of an outer..., Section 213, VA may provide a monetary allowance for the private purchase of an outer burial receptacle...

75 FR 1454 - Allowance for Private Purchase of an Outer Burial Receptacle in Lieu of a Government-Furnished...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-11

... DEPARTMENT OF VETERANS AFFAIRS Allowance for Private Purchase of an Outer Burial Receptacle in... Department of Veterans Affairs (VA) to provide a monetary allowance towards the private purchase of an outer..., Section 213, VA may provide a monetary allowance for the private purchase of an outer burial receptacle...

78 FR 76712 - Allowance for Private Purchase of an Outer Burial Receptacle in Lieu of a Government-Furnished...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-18

... DEPARTMENT OF VETERANS AFFAIRS Allowance for Private Purchase of an Outer Burial Receptacle in... Department of Veterans Affairs (VA) to provide a monetary allowance towards the private purchase of an outer..., Section 213, VA may provide a monetary allowance for the private purchase of an outer burial receptacle...

76 FR 55090 - Commercial Lease of Submerged Lands for Renewable Energy Development on the Outer Continental Shelf

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-06

...-2011-0039] Commercial Lease of Submerged Lands for Renewable Energy Development on the Outer... renewable energy leases on the Outer Continental Shelf. In the preamble to the April 29, 2009, Final Rule, ``Renewable Energy and Alternate Uses of Existing Facilities on the Outer Continental Shelf,'' BOEMRE stated...

Methods and apparatus for radially compliant component mounting

DOEpatents

Bulman, David Edward [Cincinnati, OH; Darkins, Jr., Toby George; Stumpf, James Anthony [Columbus, IN; Schroder, Mark S [Greenville, SC; Lipinski, John Joseph [Simpsonville, SC

2012-03-27

Methods and apparatus for a mounting assembly for a liner of a gas turbine engine combustor are provided. The combustor includes a combustor liner and a radially outer annular flow sleeve. The mounting assembly includes an inner ring surrounding a radially outer surface of the liner and including a plurality of axially extending fingers. The mounting assembly also includes a radially outer ring coupled to the inner ring through a plurality of spacers that extend radially from a radially outer surface of the inner ring to the outer ring.

Rotation flexure with temperature controlled modal frequency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salas, Theodore E.; Barney, Patrick S.; Ison, Aaron M.

A flexure bearing includes an inner race, an outer race, and a plurality of substantially planar radially extending blades coupled between the inner and outer race. The blades have a thickness that is thinner than a thickness of the inner and outer races. The inner race, outer race, and blades have substantially the same height. At least one heating element is coupled to the inner race and/or the outer race. The heating element is configured to apply heat to the race that it is coupled to in order to tune the flexure bearing.

Strategy for outer planets exploration

NASA Technical Reports Server (NTRS)

1975-01-01

NASA's Planetary Programs Office formed a number of scientific working groups to study in depth the potential scientific return from the various candidate missions to the outer solar system. The results of these working group studies were brought together in a series of symposia to evaluate the potential outer planet missions and to discuss strategies for exploration of the outer solar system that were consistent with fiscal constraints and with anticipated spacecraft and launch vehicle capabilities. A logical, scientifically sound, and cost effective approach to exploration of the outer solar system is presented.

Particle trap to sheath contact for a gas-insulated transmission line having a corrugated outer conductor

DOEpatents

Fischer, William H.; Cookson, Alan H.; Yoon, Kue H.

1984-04-10

A particle trap to outer elongated conductor or sheath contact for gas-insulated transmission lines. The particle trap to outer sheath contact of the invention is applicable to gas-insulated transmission lines having either corrugated or non-corrugated outer sheaths. The contact of the invention includes an electrical contact disposed on a lever arm which in turn is rotatably disposed on the particle trap and biased in a direction to maintain contact between the electrical contact and the outer sheath.

Material with core-shell structure

DOEpatents

Luhrs, Claudia [Rio Rancho, NM; Richard, Monique N [Ann Arbor, MI; Dehne, Aaron [Maumee, OH; Phillips, Jonathan [Rio Rancho, NM; Stamm, Kimber L [Ann Arbor, MI; Fanson, Paul T [Brighton, MI

2011-11-15

Disclosed is a material having a composite particle, the composite particle including an outer shell and a core. The core is made from a lithium alloying material and the outer shell has an inner volume that is greater in size than the core of the lithium alloying material. In some instances, the outer mean diameter of the outer shell is less than 500 nanometers and the core occupies between 5 and 99% of the inner volume. In addition, the outer shell can have an average wall thickness of less than 100 nanometers.

Evidence of early ultrastructural photoreceptor abnormalities in light-induced retinal degeneration using spectral domain optical coherence tomography.

PubMed

Aziz, Mehak K; Ni, Aiguo; Esserman, Denise A; Chavala, Sai H

2014-07-01

To study spatiotemporal in vivo changes in retinal morphology and quantify thickness of retinal layers in a mouse model of light-induced retinal degeneration using spectral domain optical coherence tomography (SD-OCT). BALB/c mice were exposed to 5000 lux of constant light for 3 h. SD-OCT images were taken 3 h, 24 h, 3 days, 1 week and 1 month after light exposure and were compared with histology at the same time points. SD-OCT images were also taken at 0, 1 and 2 h after light exposure in order to analyse retinal changes at the earliest time points. The thickness of retinal layers was measured using the Bioptigen software InVivoVue Diver. SD-OCT demonstrated progressive outer retinal thinning. 3 h after light exposure, the outer nuclear layer converted from hyporeflective to hyper-reflective. At 24 h, outer retinal bands and nuclear layer demonstrated similar levels of hyper-reflectivity. Significant variations in outer retinal thickness, vitreous opacities and retinal detachments occurred within days of injury. Thinning of the retina was observed at 1 month after injury. It was also determined that outer nuclear layer changes precede photoreceptor segment structure disintegration and the greatest change in segment structure occurs between 1 and 2 h after light exposure. Longitudinal SD-OCT reveals intraretinal changes that cannot be observed by histopathology at early time points in the light injury model. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Structural and functional changes associated with normal and abnormal fundus autofluorescence in patients with retinitis pigmentosa.

PubMed

Greenstein, Vivienne C; Duncker, Tobias; Holopigian, Karen; Carr, Ronald E; Greenberg, Jonathan P; Tsang, Stephen H; Hood, Donald C

2012-02-01

To analyze the structure and visual function of regions bordering the hyperautofluorescent ring/arcs in retinitis pigmentosa. Twenty-one retinitis pigmentosa patients (21 eyes) with rings/arcs and 21 normal individuals (21 eyes) were studied. Visual sensitivity in the central 10° was measured with microperimetry. Retinal structure was evaluated with spectral-domain optical coherence tomography. The distance from the fovea to disruption/loss of the inner outer segment (IS/OS) junction and thicknesses of the total receptor plus retinal pigment epithelial complex and outer segment plus retinal pigment epithelial complex layers were measured. Results were compared with measurements of the distance from the fovea to the inner and outer borders of the ring/arc seen on fundus autofluorescence. Disruption/loss of the inner outer segment junction occurred closer to the inner border of the ring/arc and it was closer to the fovea in eight eyes. For 19 eyes, outer segment plus and receptor plus RPE complex thicknesses were significantly decreased at locations closer to the fovea than the appearance of the inner border of hyperautofluorescence. Mean visual sensitivity was decreased inside, across, and outside the ring/arc by 3.5 ± 3.8, 8.9 ± 4.8, and 17.0 ± 2.4 dB, respectively. Structural and functional changes can occur inside the hyperfluorescent ring/arc in retinitis pigmentosa.

Densification control and analysis of outer shell of new high-temperature vacuum insulated composite

NASA Astrophysics Data System (ADS)

Wang, Yang; Chen, Zhaofeng; Jiang, Yun; Yu, Shengjie; Xu, Tengzhou; Li, Binbin; Chen, Zhou

2017-11-01

A novel high temperature vacuum insulated composite with low thermal conductivity composed of SiC foam core material and sealing outer shell is discussed, which will have a great potential to be used as thermal protection system material. In this composite, the outer shell is the key to maintain its internal vacuum, which is consisted of 2.5D C/C and SiC coating. So the densification processes of outer shell, including 2.5D braiding process, chemical vapor infiltration (CVI) pyrolytic carbon (PyC) process, polymer infiltration and pyrolysis (PIP) glassy carbon (GC) process and chemical vapor deposition (CVD) SiC process, are focused in this paper. The measuring result of the gas transmission quantity of outer shell is only 0.14 cm3/m2 · d · Pa after 5 times CVD processes, which is two order of magnitude lower than that sample deposited one time. After 10 times thermal shock cycles, the gas transmission quantity increases to 1.2 cm3/m2 · d · Pa. The effective thermal conductivity of high temperature vacuum insulated composite ranged from 0.19 W m-1 K-1 to 0.747 W m-1 K-1 within the temperature from 20 °C to 900 °C. Even after 10 thermal shock cycles, the variation of the effective thermal conductivity is still consistent with that without treatments.

Appendiceal outer diameter as an indicator for differentiating appendiceal mucocele from appendicitis.

PubMed

Lien, Wan-Ching; Huang, Shih-Pei; Chi, Chun-Lin; Liu, Kao-Lang; Lin, Ming-Tsan; Lai, Ting-I; Liu, Yueh-Ping; Wang, Hsiu-Po

2006-11-01

Patients with appendiceal mucocele (AM) commonly present with features indicative of acute appendicitis. In emergency departments, accurate preoperative diagnosis is crucial to prompt appropriate treatment. This study investigates the clinical and sonographic characteristics of AM, which may prove useful in preoperatively differentiating AM from appendicitis. This case-control study compares the clinical and sonographic findings of 16 histologically confirmed AM with sex- and age-matched control subjects (n = 64) with appendicitis by a 1:4 ratio. Conditional logistic regression was applied to estimate the odds ratio (OR) and 95% confidence intervals (CI) of clinical and sonographic parameters associated with AM. Univariate analysis demonstrated that the larger appendiceal outer diameter by sonography was positively correlated with diagnosis of AM (OR, 2.31; 95% CI, 1.42-3.72) and right lower quadrant abdominal pain was negatively correlated (OR, 0.38; 95% CI, 0.17-0.82). However, multiple regression analysis suggested that only outer diameter remained significant (OR, 2.21; 95% CI, 1.36-3.59) after adjusting for age, sex, and right lower quadrant pain. An outer diameter of 15 mm or more was predictive of AM diagnosis, with a sensitivity of 83% and specificity of 92%. When the threshold is set at 15 mm, appendiceal outer diameter by sonography is a useful preoperative measurement for differentiating between AM and acute appendicitis.

Investigation of compound jet electrospray: Particle encapsulation

NASA Astrophysics Data System (ADS)

Mei, Fan; Chen, Da-Ren

2007-10-01

Experiments were performed to investigate the effect of surface tension on the particle encapsulation formation in the compound jet electrospray process. The outer liquid used in this study were olive oil and mineral oil; and inner liquids were ethanol, tri-butyl phosphate, ethylene glycol, and triethylene glycol. It was found that the core-shell structured droplets are formed only when the ratio of charge relaxation lengths of the inner and outer jets [i.e., rO*/rI*, where r *=(Qɛɛ0/K)1/3, in which ɛ is the dielectric constant of liquid] is less than 500, and the ratio of inertial breakup lengths of the inner and outer jets [i.e., RO*/RI*, where R *=(ρQ2/γ)1/3, in which ρ and γ are the density and surface tension of liquid, respectively] is less than 0.015. In this work we further studied the effect of inner and outer liquid flow rates on the size of compound droplets using an Aerosizer (TSI model 3220). The parameters affecting the droplet size distribution were obtained. We also observed that the spray current emitted through the compound jet was merely a linear function of the inner jet flow rate. This observation implies that olive oil and mineral oil, as the outer liquids, serve as an electrically insulated layer during the spray process.

On the Effect of Geomagnetic Storms on Relativistic Electrons in the Outer Radiation Belt: Van Allen Probes Observations

NASA Astrophysics Data System (ADS)

Moya, Pablo S.; Pinto, Víctor A.; Sibeck, David G.; Kanekal, Shrikanth G.; Baker, Daniel N.

2017-11-01

Using Van Allen Probes Energetic Particle, Composition, and Thermal Plasma-Relativistic Electron-Proton Telescope (ECT-REPT) observations, we performed a statistical study on the effect of geomagnetic storms on relativistic electrons fluxes in the outer radiation belt for 78 storms between September 2012 and June 2016. We found that the probability of enhancement, depletion, and no change in flux values depends strongly on L and energy. Enhancement events are more common for ˜2 MeV electrons at L ˜ 5, and the number of enhancement events decreases with increasing energy at any given L shell. However, considering the percentage of occurrence of each kind of event, enhancements are more probable at higher energies, and the probability of enhancement tends to increases with increasing L shell. Depletion are more probable for 4-5 MeV electrons at the heart of the outer radiation belt, and no-change events are more frequent at L < 3.5 for E ˜ 3 MeV particles. Moreover, for L > 4.5 the probability of enhancement, depletion, or no-change response presents little variation for all energies. Because these probabilities remain relatively constant as a function of radial distance in the outer radiation belt, measurements obtained at geosynchronous orbit may be used as a proxy to monitor E≥1.8 MeV electrons in the outer belt.

The MASSIVE survey - VIII. Stellar velocity dispersion profiles and environmental dependence of early-type galaxies

NASA Astrophysics Data System (ADS)

Veale, Melanie; Ma, Chung-Pei; Greene, Jenny E.; Thomas, Jens; Blakeslee, John P.; Walsh, Jonelle L.; Ito, Jennifer

2018-02-01

We measure the radial profiles of the stellar velocity dispersions, σ(R), for 90 early-type galaxies (ETGs) in the MASSIVE survey, a volume-limited integral-field spectroscopic (IFS) galaxy survey targeting all northern-sky ETGs with absolute K-band magnitude MK < -25.3 mag, or stellar mass M* ≳ 4 × 1011M⊙, within 108 Mpc. Our wide-field 107 arcsec × 107 arcsec IFS data cover radii as large as 40 kpc, for which we quantify separately the inner (2 kpc) and outer (20 kpc) logarithmic slopes γinner and γouter of σ(R). While γinner is mostly negative, of the 56 galaxies with sufficient radial coverage to determine γouter we find 36 per cent to have rising outer dispersion profiles, 30 per cent to be flat within the uncertainties and 34 per cent to be falling. The fraction of galaxies with rising outer profiles increases with M* and in denser galaxy environment, with 10 of the 11 most massive galaxies in our sample having flat or rising dispersion profiles. The strongest environmental correlations are with local density and halo mass, but a weaker correlation with large-scale density also exists. The average γouter is similar for brightest group galaxies, satellites and isolated galaxies in our sample. We find a clear positive correlation between the gradients of the outer dispersion profile and the gradients of the velocity kurtosis h4. Altogether, our kinematic results suggest that the increasing fraction of rising dispersion profiles in the most massive ETGs are caused (at least in part) by variations in the total mass profiles rather than in the velocity anisotropy alone.

SU-E-I-37: Low-Dose Real-Time Region-Of-Interest X-Ray Fluoroscopic Imaging with a GPU-Accelerated Spatially Different Bilateral Filtering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chung, H; Lee, J; Pua, R

2014-06-01

Purpose: The purpose of our study is to reduce imaging radiation dose while maintaining image quality of region of interest (ROI) in X-ray fluoroscopy. A low-dose real-time ROI fluoroscopic imaging technique which includes graphics-processing-unit- (GPU-) accelerated image processing for brightness compensation and noise filtering was developed in this study. Methods: In our ROI fluoroscopic imaging, a copper filter is placed in front of the X-ray tube. The filter contains a round aperture to reduce radiation dose to outside of the aperture. To equalize the brightness difference between inner and outer ROI regions, brightness compensation was performed by use of amore » simple weighting method that applies selectively to the inner ROI, the outer ROI, and the boundary zone. A bilateral filtering was applied to the images to reduce relatively high noise in the outer ROI images. To speed up the calculation of our technique for real-time application, the GPU-acceleration was applied to the image processing algorithm. We performed a dosimetric measurement using an ion-chamber dosimeter to evaluate the amount of radiation dose reduction. The reduction of calculation time compared to a CPU-only computation was also measured, and the assessment of image quality in terms of image noise and spatial resolution was conducted. Results: More than 80% of dose was reduced by use of the ROI filter. The reduction rate depended on the thickness of the filter and the size of ROI aperture. The image noise outside the ROI was remarkably reduced by the bilateral filtering technique. The computation time for processing each frame image was reduced from 3.43 seconds with single CPU to 9.85 milliseconds with GPU-acceleration. Conclusion: The proposed technique for X-ray fluoroscopy can substantially reduce imaging radiation dose to the patient while maintaining image quality particularly in the ROI region in real-time.« less

49 CFR 179.400-3 - Type.

Code of Federal Regulations, 2010 CFR

2010-10-01

... essentially concentric within an outer jacket of circular cross section, with the out of roundness of both the inner tank and outer jacket limited in accordance with Paragraph UG-80 in Section VIII of the ASME Code (IBR, see § 171.7 of this subchapter); (2) Have the annular space evacuated after filling the annular...

49 CFR 179.400-3 - Type.

Code of Federal Regulations, 2011 CFR

2011-10-01

... essentially concentric within an outer jacket of circular cross section, with the out of roundness of both the inner tank and outer jacket limited in accordance with Paragraph UG-80 in Section VIII of the ASME Code (IBR, see § 171.7 of this subchapter); (2) Have the annular space evacuated after filling the annular...

49 CFR 179.400-3 - Type.

Code of Federal Regulations, 2012 CFR

2012-10-01

... essentially concentric within an outer jacket of circular cross section, with the out of roundness of both the inner tank and outer jacket limited in accordance with Paragraph UG-80 in Section VIII of the ASME Code (IBR, see § 171.7 of this subchapter); (2) Have the annular space evacuated after filling the annular...

49 CFR 179.400-3 - Type.

Code of Federal Regulations, 2014 CFR

2014-10-01

... essentially concentric within an outer jacket of circular cross section, with the out of roundness of both the inner tank and outer jacket limited in accordance with Paragraph UG-80 in Section VIII of the ASME Code (IBR, see § 171.7 of this subchapter); (2) Have the annular space evacuated after filling the annular...

49 CFR Appendix D to Part 178 - Thermal Resistance Test

Code of Federal Regulations, 2010 CFR

2010-10-01

... must be large enough in size to fully house the test outer package without clearance problems. The test....3Instrumentation. A calibrated recording device or a computerized data acquisition system with an appropriate range... Configuration. Each outer package material type and design must be tested, including any features such as...

STRUCTURAL ASSESSMENT OF HYPERAUTOFLUORESCENT RING IN PATIENTS WITH RETINITIS PIGMENTOSA

PubMed Central

LIMA, LUIZ H.; CELLA, WENER; GREENSTEIN, VIVIENNE C.; WANG, NAN-KAI; BUSUIOC, MIHAI; THEODORE SMITH, R.; YANNUZZI, LAWRENCE A.; TSANG, STEPHEN H.

2009-01-01

Purpose To analyze the retinal structure underlying the hyperautofluorescent ring visible on fundus autofluorescence in patients with retinitis pigmentosa. Methods Twenty-four eyes of 13 patients with retinitis pigmentosa, aged 13 years to 67 years, were studied. The integrity of the photoreceptor cilia, also known as the inner/outer segment junction of the photoreceptors, the outer nuclear layer, and retinal pigment epithelium, was evaluated outside, across, and inside the ring with spectral-domain optical coherence tomography (OCT). Results Inside the foveal area, fundus autofluorescence did not detect abnormalities. Outside the ring, fundus autofluorescence revealed hypoautofluorescence compatible with the photoreceptor/retinal pigment epithelium degeneration. Spectral-domain OCT inside the ring, in the area of normal foveal fundus autofluorescence, revealed an intact retinal structure in all eyes and total retinal thickness values that were within normal limits. Across the ring, inner/outer segment junction disruption was observed and the outer nuclear layer was decreased in thickness in a centrifugal direction in all eyes. Outside the hyperautofluorescent ring, the inner/outer segment junction and the outer nuclear layer appeared to be absent and there were signs of retinal pigment epithelium degeneration. Conclusion Disruption of the inner/outer segment junction and a decrease in outer retinal thickness were found across the central hyperautofluorescent ring seen in retinitis pigmentosa. Outer segment phagocytosis by retinal pigment epithelium is necessary for the formation of an hyperautofluorescent ring. PMID:19584660

Progressive outer retinal necrosis associated with occlusive vasculitis in acquired immunodeficiency syndrome.

PubMed

Tseng, Chien-Chi; Chen, San-Ni; Hwang, Jiunn-Feng; Lin, Chun-Ju; Chen, Huan-Sheng

2015-05-01

A 45-year-old man, a case of acquired immunodeficiency syndrome, received a highly active antiretroviral therapy at the outpatient service for 4 years without regular follow-up. He experienced progressively blurred vision for 6 months and a cutaneous zoster on his back 3 months ago. He was diagnosed with progressive outer retinal necrosis by polymerase chain reaction-restriction fragment length polymorphism using an aqueous humor sample, which revealed an existence of varicella zoster virus. He was given a combination of systemic, intravitreal antiviral and a highly active antiretroviral therapy. Occlusive vasculitis, an unusual finding for progressive outer retinal necrosis, developed in both eyes 1 week after the secondary intravitreal injection. Unfortunately, his vision deteriorated to no light perception in both eyes within 2 weeks. Progressive outer retinal necrosis is characterized clinically as showing minimal or no inflammation in the aqueous and vitreous humors, absence of retinal vasculitis, and patches of yellowish spots located deep in the retina. Physicians should pay attention to this rare case of progressive outer retinal necrosis associated occlusive vasculitis with very poor prognosis in spite of aggressive treatment. Copyright © 2015. Published by Elsevier B.V.

Decomposition of the Seismic Source Using Numerical Simulations and Observations of Nuclear Explosions

DTIC Science & Technology

2017-05-31

SUBJECT TERMS nonlinear finite element calculations, nuclear explosion monitoring, topography 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18...3D North Korea calculations........ Figure 6. The CRAM 3D finite element outer grid (left) is rectangular......................... Figure 7. Stress...Figure 6. The CRAM 3D finite element outer grid (left) is rectangular. The inner grid (center) is shaped to match the shape of the explosion shock wave

77 FR 71612 - Atlantic Wind Lease Sale 2 (ATLW2) Commercial Leasing for Wind Power on the Outer Continental...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-03

... Wind Lease Sale 2 (ATLW2) Commercial Leasing for Wind Power on the Outer Continental Shelf Offshore...), Interior. ACTION: Proposed Sale Notice for commercial leasing for wind power on the Outer Continental Shelf... sale of commercial wind energy leases on the Outer Continental Shelf (OCS) offshore Rhode Island and...

Identification of a novel type III secretion-associated outer membrane-bound protein from Xanthomonas campestris pv. campestris

PubMed Central

Li, Lei; Li, Rui-Fang; Ming, Zhen-Hua; Lu, Guang-Tao; Tang, Ji-Liang

2017-01-01

Many bacterial pathogens employ the type III secretion system (T3SS) to translocate effector proteins into eukaryotic cells to overcome host defenses. To date, most of our knowledge about the T3SS molecular architecture comes from the studies on animal pathogens. In plant pathogens, nine Hrc proteins are believed to be structural components of the T3SS, of which HrcC and HrcJ form the outer and inner rings of the T3SS, respectively. Here, we demonstrated that a novel outer membrane-bound protein (HpaM) of Xanthomonas campestris pv. campestris is critical for the type III secretion and is structurally and functionally conserved in phytopathogenic Xanthomonas spp. We showed that the C-terminus of HpaM extends into the periplasm to interact physically with HrcJ and the middle part of HpaM interacts physically with HrcC. It is clear that the outer and inner rings compose the main basal body of the T3SS apparatus in animal pathogens. Therefore, we presume that HpaM may act as a T3SS structural component, or play a role in assisting assembling or affecting the stability of the T3SS apparatus. HpaM is a highly prevalent and specific protein in Xanthomonas spp., suggesting that the T3SS of Xanthomonas is distinctive in some aspects from other pathogens. PMID:28198457

Delimitation of air space and outer space - Is such a boundary needed now?

NASA Technical Reports Server (NTRS)

Hosenball, S. N.

1983-01-01

A discussion is presented of the question of establishing a boundary between air space and outer space. Four theories and approaches for establishing a delimitation between air space and outer space are examined. Spatial approaches include demarcation based on the division of the atmosphere into layers, demarcation based on aerodynamic characteristics of flight instrumentalities (von Karman Line), demarcation according to the lowest perigee of an orbiting satellite, and demarcation based upon the earth's gravitational effects. The functionalist approach is based on the delimitation or definition of the air space/outer space regime by the purpose and activities for which an object is designed in air space or outer space. The arbitrarist approach is supported by those who wish to draw an arbitrary line between air space and outer space. It is proposed that a pragmatist approach will be more useful than the other three approaches. The pragmatist approach advocates not establishing a boundary between air space and outer space at the present time or in the immediate future. It is argued that there are at present no serious problems that can be resolved by the definition/delimitation of air space and outer space.

Wedge assembly for electrical transformer component spacing

DOEpatents

Baggett, Franklin E.; Cage, W. Franklin

1991-01-01

A wedge assembly that is easily inserted between two surfaces to be supported thereby, and thereafter expanded to produce a selected spacing between those surfaces. This wedge assembly has two outer members that are substantially identical except that they are mirror images of each other. Oppositely directed faces of these of these outer members are substantially parallel for the purpose of contacting the surfaces to be separated. The outer faces of these outer members that are directed toward each other are tapered so as to contact a center member having complementary tapers on both faces. A washer member is provided to contact a common end of the outer members, and a bolt member penetrates this washer and is threadably received in a receptor of the center member. As the bolt member is threaded into the center member, the center member is drawn further into the gap between the outer members and thereby separates these outer members to contact the surfaces to be separated. In the preferred embodiment, the contacting surfaces of the outer member and the center member are provided with guide elements. The wedge assembly is described for use in separating the secondary windings from the laminations of an electrical power transformer.

Hybrid particle traps and conditioning procedure for gas insulated transmission lines

DOEpatents

Dale, Steinar J.; Cookson, Alan H.

1982-01-01

A gas insulated transmission line includes an outer sheath, an inner condor within the outer sheath, insulating supports supporting the inner conductor within the outer sheath, and an insulating gas electrically insulating the inner conductor from the outer sheath. An apertured particle trapping ring is disposed within the outer sheath, and the trapping ring has a pair of dielectric members secured at each longitudinal end thereof, with the dielectric members extending outwardly from the trapping ring along an arc. A support sheet having an adhesive coating thereon is secured to the trapping ring and disposed on the outer sheath within the low field region formed between the trapping ring and the outer sheath. A conditioning method used to condition the transmission line prior to activation in service comprises applying an AC voltage to the inner conductor in a plurality of voltage-time steps, with the voltage-time steps increasing in voltage magnitude while decreasing in time duration.

Tryptophan 375 stabilizes the outer-domain core of gp120 for HIV vaccine immunogen design.

PubMed

Hu, Duoyi; Bowder, Dane; Wei, Wenzhong; Thompson, Jesse; Wilson, Mark A; Xiang, Shi-Hua

2017-05-25

The outer-domain core of gp120 may serve as a better HIV vaccine immunogen than the full-length gp120 because of its greater stability and immunogenicity. In our previous report, we introduced two disulfide bonds to the outer-domain core of gp120 to fix its conformation into a CD4-bound state, which resulted in a significant increase in its immunogenicity when compared to the wild-type outer-domain core. In this report, to further improve the immunogenicity of the outer-domain core based immunogen, we have introduced a Tryptophan residue at gp120 amino acid sequence position 375 (375S/W). Our data from immunized guinea pigs indeed shows a striking increase in the immune response due to this stabilized core outer-domain. Therefore, we conclude that the addition of 375W to the outer-domain core of gp120 further stabilizes the structure of immunogen and increases the immunogenicity. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Swirling structure for mixing two concentric fluid flows at nozzle outlet

DOEpatents

Mensink, D.L.

1993-07-20

A nozzle device is described for causing two fluids to mix together. In particular, a spray nozzle comprises two hollow, concentric housings, an inner housing and an outer housing. The inner housing has a channel formed therethrough for a first fluid. Its outer surface cooperates with the interior surface of the outer housing to define the second channel for a second fluid. The outer surface of the inner housing and the inner surface of the outer housing each carry a plurality of vanes that interleave but do not touch, each vane of one housing being between two vanes of the other housing. The vanes are curved and the inner surface of the outer housing and the outer surface of the inner housing converge to narrow the second channel. The shape of second channel results in a swirling, accelerating second fluid that will impact the first fluid just past the end of the nozzle where mixing will take place.

Turbine stator vane segment having internal cooling circuits

DOEpatents

Jones, Raymond Joseph; Burns, James Lee; Bojappa, Parvangada Ganapathy; Jones, Schotsch Margaret

2003-01-01

A turbine stator vane includes outer and inner walls each having outer and inner chambers and a vane extending between the outer and inner walls. The vane includes first, second, third, fourth and fifth cavities for flowing a cooling medium. The cooling medium enters the outer chamber of the outer wall, flows through an impingement plate for impingement cooling of the outer band wall defining in part the hot gas path and through openings in the first, second and fourth cavities for flow radially inwardly, cooling the vane. The spent cooling medium flows into the inner wall and inner chamber for flow through an impingement plate radially outwardly to cool the inner wall. The spent cooling medium flows through the third cavity for egress from the turbine vane segment from the outer wall. The first, second or third cavities contain inserts having impingement openings for impingement cooling of the vane walls. The fifth cavity provides air cooling for the trailing edge.

Gas turbine row #1 steam cooled vane

DOEpatents

Cunha, Frank J.

2000-01-01

A design for a vane segment having a closed-loop steam cooling system is provided. The vane segment comprises an outer shroud, an inner shroud and an airfoil, each component having a target surface on the inside surface of its walls. A plurality of rectangular waffle structures are provided on the target surface to enhance heat transfer between each component and cooling steam. Channel systems are provided in the shrouds to improve the flow of steam through the shrouds. Insert legs located in cavities in the airfoil are also provided. Each insert leg comprises outer channels located on a perimeter of the leg, each outer channel having an outer wall and impingement holes on the outer wall for producing impingement jets of cooling steam to contact the airfoil's target surface. Each insert leg further comprises a plurality of substantially rectangular-shaped ribs located on the outer wall and a plurality of openings located between outer channels of the leg to minimize cross flow degradation.

Effect of cage design on characteristics of high-speed-jet-lubricated 35-millimeter-bore ball bearing. [turbojet engines

NASA Technical Reports Server (NTRS)

Schuller, F. T.; Pinel, S. I.; Signer, H. R.

1980-01-01

Parametric tests were conducted with a 35 mm bore angular contact ball bearing with a double outer land guided cage. Provisions were made for jet lubrication and outer-ring cooling of the bearing. Test conditions included a combined thrust and radial load at nominal shaft speeds of 48,000 rpm, and an oil-in temperature of 394 K (250 F). Successful operation of the test bearing was accomplished up to 2.5 million DN. Test results were compared with those obtained with similar bearing having a single outer land guided cage. Higher temperatures were generated with the double outer land guided cage bearing, and bearing power loss and cage slip were greater. Cooling the outer ring resulted in a decrease in overall bearing operating temperature.

Atmospheric Mining in the Outer Solar System: Resource Capturing, Storage, and Utilization

NASA Technical Reports Server (NTRS)

Palaszewski, Bryan

2014-01-01

Atmospheric mining in the outer solar system has been investigated as a means of fuel production for high energy propulsion and power. Fusion fuels such as helium 3 and hydrogen can be wrested from the atmospheres of Uranus and Neptune and either returned to Earth or used in-situ for energy production. Helium 3 and hydrogen (deuterium, etc.) were the primary gases of interest with hydrogen being the primary propellant for nuclear thermal solid core and gas core rocket-based atmospheric flight. A series of analyses were undertaken to investigate resource capturing aspects of atmospheric mining in the outer solar system. This included the gas capturing rate for hydrogen helium 4 and helium 3, storage options, and different methods of direct use of the captured gases. Additional supporting analyses were conducted to illuminate vehicle sizing and orbital transportation issues.

Effect of Steel Framing for Securing Drywall Panels on Thermal and Humidity Parameters of the Outer Walls

NASA Astrophysics Data System (ADS)

Major, Maciej; Kosiń, Mariusz

2017-12-01

The paper analyses the effect of steel framing used to secure drywall panels on thermal and humidity properties of outer walls. In the practice of building a light structure, the most popular components are steel and wood studs. They are used to obtain framing for building a wall (an outer wall in this study). Analysis presented in this study concerned the corner of the outer wall build using the technology of light steel framing. Computer simulation was used to perform thermal and humidity analysis for the joint of the outer wall.

Accurate quantification of local changes for carotid arteries in 3D ultrasound images using convex optimization-based deformable registration

NASA Astrophysics Data System (ADS)

Cheng, Jieyu; Qiu, Wu; Yuan, Jing; Fenster, Aaron; Chiu, Bernard

2016-03-01

Registration of longitudinally acquired 3D ultrasound (US) images plays an important role in monitoring and quantifying progression/regression of carotid atherosclerosis. We introduce an image-based non-rigid registration algorithm to align the baseline 3D carotid US with longitudinal images acquired over several follow-up time points. This algorithm minimizes the sum of absolute intensity differences (SAD) under a variational optical-flow perspective within a multi-scale optimization framework to capture local and global deformations. Outer wall and lumen were segmented manually on each image, and the performance of the registration algorithm was quantified by Dice similarity coefficient (DSC) and mean absolute distance (MAD) of the outer wall and lumen surfaces after registration. In this study, images for 5 subjects were registered initially by rigid registration, followed by the proposed algorithm. Mean DSC generated by the proposed algorithm was 79:3+/-3:8% for lumen and 85:9+/-4:0% for outer wall, compared to 73:9+/-3:4% and 84:7+/-3:2% generated by rigid registration. Mean MAD of 0:46+/-0:08mm and 0:52+/-0:13mm were generated for lumen and outer wall respectively by the proposed algorithm, compared to 0:55+/-0:08mm and 0:54+/-0:11mm generated by rigid registration. The mean registration time of our method per image pair was 143+/-23s.

Atmospheric Mining in the Outer Solar System: Resource Capturing, Storage, and Utilization

NASA Technical Reports Server (NTRS)

Palaszewski, Bryan

2012-01-01

Atmospheric mining in the outer solar system has been investigated as a means of fuel production for high energy propulsion and power. Fusion fuels such as Helium 3 (3He) and hydrogen can be wrested from the atmospheres of Uranus and Neptune and either returned to Earth or used in-situ for energy production. Helium 3 and hydrogen (deuterium, etc.) were the primary gases of interest with hydrogen being the primary propellant for nuclear thermal solid core and gas core rocket-based atmospheric flight. A series of analyses were undertaken to investigate resource capturing aspects of atmospheric mining in the outer solar system. This included the gas capturing rate for hydrogen helium 4 and helium 3, storage options, and different methods of direct use of the captured gases. Additional supporting analyses were conducted to illuminate vehicle sizing and orbital transportation issues.

Structural basis for maintenance of bacterial outer membrane lipid asymmetry.

PubMed

Abellón-Ruiz, Javier; Kaptan, Shreyas S; Baslé, Arnaud; Claudi, Beatrice; Bumann, Dirk; Kleinekathöfer, Ulrich; van den Berg, Bert

2017-12-01

The Gram-negative bacterial outer membrane (OM) is a unique bilayer that forms an efficient permeation barrier to protect the cell from noxious compounds 1 , 2 . The defining characteristic of the OM is lipid asymmetry, with phospholipids comprising the inner leaflet and lipopolysaccharides comprising the outer leaflet 1-3 . This asymmetry is maintained by the Mla pathway, a six-component system that is widespread in Gram-negative bacteria and is thought to mediate retrograde transport of misplaced phospholipids from the outer leaflet of the OM to the cytoplasmic membrane 4 . The OM lipoprotein MlaA performs the first step in this process via an unknown mechanism that does not require external energy input. Here we show, using X-ray crystallography, molecular dynamics simulations and in vitro and in vivo functional assays, that MlaA is a monomeric α-helical OM protein that functions as a phospholipid translocation channel, forming a ~20-Å-thick doughnut embedded in the inner leaflet of the OM with a central, amphipathic pore. This architecture prevents access of inner leaflet phospholipids to the pore, but allows outer leaflet phospholipids to bind to a pronounced ridge surrounding the channel, followed by diffusion towards the periplasmic space. Enterobacterial MlaA proteins form stable complexes with OmpF/C 5,6 , but the porins do not appear to play an active role in phospholipid transport. MlaA represents a lipid transport protein that selectively removes outer leaflet phospholipids to help maintain the essential barrier function of the bacterial OM.

Atmospheric Mining in the Outer Solar System: Aerial Vehicle Mission and Design Issues

NASA Technical Reports Server (NTRS)

Palaszewski, Bryan

2015-01-01

Atmospheric mining in the outer solar system has been investigated as a means of fuel production for high energy propulsion and power. Fusion fuels such as Helium 3 (3He) and deuterium can be wrested from the atmospheres of Uranus and Neptune and either returned to Earth or used in-situ for energy production. Helium 3 and deuterium were the primary gases of interest with hydrogen being the primary propellant for nuclear thermal solid core and gas core rocket-based atmospheric flight. A series of analyses were undertaken to investigate resource capturing aspects of atmospheric mining in the outer solar system. This included the gas capturing rate, storage options, and different methods of direct use of the captured gases. While capturing 3He, large amounts of hydrogen and 4He are produced. With these two additional gases, the potential for fueling small and large fleets of additional exploration and exploitation vehicles exists. The mining aerospacecraft (ASC) could fly through the outer planet atmospheres, for global weather observations, localized storm or other disturbance investigations, wind speed measurements, polar observations, etc. Analyses of orbital transfer vehicles (OTVs), landers, and in-situ resource utilization (ISRU) mining factories are included. Preliminary observations are presented on near-optimal selections of moon base orbital locations, OTV power levels, and OTV and lander rendezvous points.

Processing of ammonia-containing ices by heavy ions and its relevance to outer Solar System surfaces

NASA Astrophysics Data System (ADS)

Pilling, Sergio; Seperuelo Duarte, Eduardo; da Silveira, Enio F.; Domaracka, Alicja; Balanzat, Emmanuel; Rothard, Hermann; Boduch, Philippe

Ammonia-containing ices have been detected or postulated as important components of the icy surfaces of planetary satellites (e.g. Enceladus, Miranda), in the outer Solar System objects (e.g. Charon, Quaoar) and in Oort cloud comets. We present experimental studies of the interaction of heavy, highly-charged, and energetic ions with ammonia-containing ices (pure NH3 ; NH3 :CO; NH3 :H2 O and NH3 :H2 O:CO) in an attempt to simulate the physical chemistry induced by heavy-ion cosmic rays and heavy-ion solar wind particles at outer Solar System surfaces. The measurements were performed inside a high vacuum chamber at the heavy-ion accelerator GANIL (Grand Accelerateur National d'Ions Lourds) in Caen, France. The gas samples were deposited onto a polished CsI substrate previously cooled to 13 K. In-situ analysis was performed by a Fourier transform infrared spectrometer (FTIR) at different ion fluences. The dissociation cross-section and sputtering yield of ammonia and other ice compounds have been determined. Half-life of frozen ammonia due to heavy ion bombardment at different Solar System surfaces has been estimated. Radiolysis products have been identified and their implications for the chemistry on outer Solar System surfaces are discussed.

Study of Plasma Flow Modes in Imploding Nested Arrays

NASA Astrophysics Data System (ADS)

Mitrofanov, K. N.; Aleksandrov, V. V.; Gritsuk, A. N.; Branitsky, A. V.; Frolov, I. N.; Grabovski, E. V.; Sasorov, P. V.; Ol'khovskaya, O. G.; Zaitsev, V. I.

2018-02-01

Results from experimental studies of implosion of nested wire and fiber arrays at currents of up to 4 MA at the Angara-5-1 facility are presented. Depending on the ratio between the radii of the inner and outer arrays, different modes of the plasma flow in the space between the inner and outer arrays were implemented: the sub-Alfvénic ( V r < V A ) and super-Alfvénic ( V r > V A ) modes and a mode with the formation of the transition shock wave (SW) region between the cascades. By varying the material of the outer array (tungsten wires or kapron fibers), it is shown that the plasma flow mode between the inner and outer arrays depends on the ratio between the plasma production rates ṁ in / ṁ out in the inner and outer arrays. The obtained experimental results are compared with the results of one-dimensional MHD simulation of the plasma flow between the arrays. Stable implosion of the inner array plasma was observed in experiments with combined nested arrays consisting of a fiber outer array and a tungsten inner array. The growth rates of magnetic Rayleigh-Taylor (MRT) instability in the inner array plasma at different numbers of fibers in the outer array and different ratios between the radii of the inner and outer arrays are compared. Suppression of MRT instability during the implosion of the inner array plasma results in the formation of a stable compact Z-pinch and generation of a soft X-ray pulse. A possible scenario of interaction between the plasmas of the inner and outer arrays is offered. The stability of the inner array plasma in the stage of final compression depends on the character of interaction of plasma jets from the outer array with the magnetic field of the inner array.

Valve assembly for use with high temperature and high pressure fluids

DOEpatents

De Feo, Angelo

1982-01-01

The valve assembly for use with high temperature and high pressure fluids has inner and outer spaced shells and a valve actuator support of inner and outer spaced members which are connected at their end portions to the inner and outer shells, respectively, to extend substantially normal to the longitudinal axis of the inner shell. A layer of resilient heat insulating material covers the outer surfaces of the inner shell and the inner actuator support member and is of a thickness to only occupy part of the spaces between the inner and outer shells and inner and outer actuator support members. The remaining portion of the space between the inner and outer shells and the space between the inner and outer members is substantially filled with a body of castable, rigid refractory material. A movable valve member is disposed in the inner shell. A valve actuator assembly is supported in the valve actuator support to extend into the inner shell for connection with the movable valve member for movement of the movable valve member to positions from a fully open to a fully closed position to control flow of fluid through the inner shell. An anchor mneans is disposed adjacent opposite sides of the axis of the valve actuator support and attached to the inner shell so that relative radial movement between the inner and outer shell is permitted by the layer of resilient heat insulating material and relative longitudinal movement of the inner shell to the outer shell is permitted in opposite directions from the anchor means to thereby maintain the functional integrity of the movable valve member by providing an area of the inner shell surrounding the movable valve member longitdinally stationary, but at the same time allowing radial movement.

The effects of external planets on inner systems: multiplicities, inclinations and pathways to eccentric warm Jupiters

NASA Astrophysics Data System (ADS)

Mustill, Alexander J.; Davies, Melvyn B.; Johansen, Anders

2017-07-01

We study how close-in systems such as those detected by Kepler are affected by the dynamics of bodies in the outer system. We consider two scenarios: outer systems of giant planets potentially unstable to planet-planet scattering and wide binaries that may be capable of driving Kozai or other secular variations of outer planets' eccentricities. Dynamical excitation of planets in the outer system reduces the multiplicity of Kepler-detectable planets in the inner system in ˜20-25 per cent of our systems. Accounting for the occurrence rates of wide-orbit planets and binary stars, ≈18 per cent of close-in systems could be destabilized by their outer companions in this way. This provides some contribution to the apparent excess of systems with a single transiting planet compared to multiple; however, it only contributes at most 25 per cent of the excess. The effects of the outer dynamics can generate systems similar to Kepler-56 (two coplanar planets significantly misaligned with the host star) and Kepler-108 (two significantly non-coplanar planets in a binary). We also identify three pathways to the formation of eccentric warm Jupiters resulting from the interaction between outer and inner systems: direct inelastic collision between an eccentric outer and an inner planet; secular eccentricity oscillations that may 'freeze out' when scattering resolves in the outer system; and scattering in the inner system followed by 'uplift', where inner planets are removed by interaction with the outer planets. In these scenarios, the formation of eccentric warm Jupiters is a signature of a past history of violent dynamics among massive planets beyond ˜1 au.

Correlation between spectral-domain OCT findings and visual acuity in X-linked retinoschisis.

PubMed

Yang, Hyun Seung; Lee, Jung Bok; Yoon, Young Hee; Lee, Joo Yong

2014-05-08

To investigate the tomographic characteristics of the outer retina and choroid and their relationship with visual acuity in X-linked juvenile retinoschisis (XLRS) patients using spectral-domain optical coherence tomography (SD-OCT). In this retrospective, observational, case-control study, we analyzed 20 eyes of 10 patients with XLRS using SD-OCT. The clinical and tomographic features of the outer retina, including the external limiting membrane (ELM), inner segment/outer segment (IS/OS) junction, cone cell outer segment tips (COST) line, photoreceptor outer segment (PROS) length, and choroid, were evaluated. As controls, 40 age-, sex-, and refraction-matched healthy eyes (1:2 matched) were randomly selected and imaged in parallel. The most prevalent area of abnormality in the outer retina layer of our patients was the outer plexiform layer (OPL; 60% of all affected eyes) and COST line (75% of all affected eyes). On average, the subfoveal choroid and PROS lengths were 35 μm thicker and 19 μm thinner, respectively, in XLRS patients (P = 0.084 and P < 0.001, respectively). A dominant IS/OS junction, COST line defects, and PROS length were related to patient best-corrected visual acuity (BCVA; P = 0.029, P = 0.001, and P < 0.001, respectively) by univariate analysis. Cone cell outer segment tips line defect and PROS length were the only factors related to BCVA in multivariate analysis (P = 0.028 and 0.003, respectively). Outer plexiform layer and photoreceptor microstructure defects are frequent in XLRS patients. Cone cell outer segment tips line defects and shortened PROS lengths as well as other photoreceptor microstructure defects may be closely related to poor vision in XLRS.

Ranging Behaviour of Commercial Free-Range Laying Hens.

PubMed

Chielo, Leonard Ikenna; Pike, Tom; Cooper, Jonathan

2016-04-26

In this study, the range use and behaviour of laying hens in commercial free-range flocks was explored. Six flocks were each visited on four separate days and data collected from their outdoor area (divided into zones based on distance from shed and available resources). These were: apron (0-10 m from shed normally without cover or other enrichments); enriched belt (10-50 m from shed where resources such as manmade cover, saplings and dust baths were provided); and outer range (beyond 50 m from shed with no cover and mainly grass pasture). Data collection consisted of counting the number of hens in each zone and recording behaviour, feather condition and nearest neighbour distance (NND) of 20 birds per zone on each visit day. In addition, we used techniques derived from ecological surveys to establish four transects perpendicular to the shed, running through the apron, enriched belt and outer range. Number of hens in each 10 m × 10 m quadrat was recorded four times per day as was the temperature and relative humidity of the outer range. On average, 12.5% of hens were found outside. Of these, 5.4% were found in the apron; 4.3% in the enriched zone; and 2.8% were in the outer range. This pattern was supported by data from quadrats, where the density of hens sharply dropped with increasing distance from shed. Consequently, NND was greatest in the outer range, least in the apron and intermediate in the enriched belt. Hens sampled in outer range and enriched belts had better feather condition than those from the apron. Standing, ground pecking, walking and foraging were the most commonly recorded activities with standing and pecking most likely to occur in the apron, and walking and foraging more common in the outer range. Use of the outer range declined with lower temperatures and increasing relative humidity, though use of apron and enriched belt was not affected by variation in these measures. These data support previous findings that outer range areas tend to be under-utilized in commercial free-range flocks and suggest positive relationships between range use, feather condition and increased behavioural opportunities and decline in the use of range in cold and/or damp conditions.

Signatures of broken protoplanetary discs in scattered light and in sub-millimetre observations

NASA Astrophysics Data System (ADS)

Facchini, Stefano; Juhász, Attila; Lodato, Giuseppe

2018-02-01

Spatially resolved observations of protoplanetary discs are revealing that their inner regions can be warped or broken from the outer disc. A few mechanisms are known to lead to such 3D structures; among them, the interaction with a stellar companion. We perform a 3D SPH simulation of a circumbinary disc misaligned by 60° with respect to the binary orbital plane. The inner disc breaks from the outer regions, precessing as a rigid body and leading to a complex evolution. As the inner disc precesses, the misalignment angle between the inner and outer discs varies by more than 100°. Different snapshots of the evolution are post-processed with a radiative transfer code, in order to produce observational diagnostics of the process. Even though the simulation was produced for the specific case of a circumbinary disc, most of the observational predictions hold for any disc hosting a precessing inner rim. Synthetic scattered light observations show strong azimuthal asymmetries, where the pattern depends strongly on the misalignment angle between the inner and outer discs. The asymmetric illumination of the outer disc leads to azimuthal variations of the temperature structure, in particular in the upper layers, where the cooling time is short. These variations are reflected in asymmetric surface brightness maps of optically thick lines, as CO J = 3-2. The kinematical information obtained from the gas lines is unique in determining the disc structure. The combination of scattered light images and (sub-)mm lines can distinguish between radial inflow and misaligned inner disc scenarios.

Herpesvirus gB-induced fusion between the virion envelope and outer nuclear membrane during virus egress is regulated by the viral US3 kinase.

PubMed

Wisner, Todd W; Wright, Catherine C; Kato, Akihisa; Kawaguchi, Yasushi; Mou, Fan; Baines, Joel D; Roller, Richard J; Johnson, David C

2009-04-01

Herpesvirus capsids collect along the inner surface of the nuclear envelope and bud into the perinuclear space. Enveloped virions then fuse with the outer nuclear membrane (NM). We previously showed that herpes simplex virus (HSV) glycoproteins gB and gH act in a redundant fashion to promote fusion between the virion envelope and the outer NM. HSV mutants lacking both gB and gH accumulate enveloped virions in herniations, vesicles that bulge into the nucleoplasm. Earlier studies had shown that HSV mutants lacking the viral serine/threonine kinase US3 also accumulate herniations. Here, we demonstrate that HSV gB is phosphorylated in a US3-dependent manner in HSV-infected cells, especially in a crude nuclear fraction. Moreover, US3 directly phosphorylated the gB cytoplasmic (CT) domain in in vitro assays. Deletion of gB in the context of a US3-null virus did not add substantially to defects in nuclear egress. The majority of the US3-dependent phosphorylation of gB involved the CT domain and amino acid T887, a residue present in a motif similar to that recognized by US3 in other proteins. HSV recombinants lacking gH and expressing either gB substitution mutation T887A or a gB truncated at residue 886 displayed substantial defects in nuclear egress. We concluded that phosphorylation of the gB CT domain is important for gB-mediated fusion with the outer NM. This suggested a model in which the US3 kinase is incorporated into the tegument layer (between the capsid and envelope) in HSV virions present in the perinuclear space. By this packaging, US3 might be brought close to the gB CT tail, leading to phosphorylation and triggering fusion between the virion envelope and the outer NM.

The presequence pathway is involved in protein sorting to the mitochondrial outer membrane.

PubMed

Wenz, Lena-Sophie; Opaliński, Lukasz; Schuler, Max-Hinderk; Ellenrieder, Lars; Ieva, Raffaele; Böttinger, Lena; Qiu, Jian; van der Laan, Martin; Wiedemann, Nils; Guiard, Bernard; Pfanner, Nikolaus; Becker, Thomas

2014-06-01

The mitochondrial outer membrane contains integral α-helical and β-barrel proteins that are imported from the cytosol. The machineries importing β-barrel proteins have been identified, however, different views exist on the import of α-helical proteins. It has been reported that the biogenesis of Om45, the most abundant signal-anchored protein, does not depend on proteinaceous components, but involves direct insertion into the outer membrane. We show that import of Om45 occurs via the translocase of the outer membrane and the presequence translocase of the inner membrane. Assembly of Om45 in the outer membrane involves the MIM machinery. Om45 thus follows a new mitochondrial biogenesis pathway that uses elements of the presequence import pathway to direct a protein to the outer membrane. © 2014 The Authors.

Cooperation of Pd-1 and LAG-3 contributes to T-cell exhaustion in anaplasma marginale-infected cattle

USDA-ARS?s Scientific Manuscript database

The CD4+ T-cell response is central for control of Anaplasma marginale infection in cattle. However, the infection induces a functional exhaustion of antigen-specific CD4+ T cells in cattle immunized with A. marginale outer membrane proteins or purified outer membranes (OM), which presumably facilit...

Imaging Shock Fronts in the Outer Ejecta of Eta Carinae

NASA Astrophysics Data System (ADS)

Smith, Nathan

2017-08-01

Although Eta Car has been imaged many times with HST to monitor the central star and the bright Homunculus Nebula, we propose the first WFC3 imaging of Eta Car to study the more extended Outer Ejecta from previous eruptions. WFC3 has two key filters that have not been used before to image Eta Car, which will provide critical physical information about its eruptive history: (1) F280N with WFC3/UVIS will produce the first Mg II 2800 image of Eta Car, the sharpest image of its complex Outer Ejecta, and will unambiguously trace shock fronts, and (2) F126N with WFC3/IR will sample [Fe II] 12567 arising in the densest post-shock gas. Eta Car is surrounded by a bright, soft X-ray shell seen in Chandra images, which arises from the fastest 1840s ejecta overtaking slower older material. Our recent proper motion measurements show that the outer knots were ejected in two outbursts several hundred years before the 1840s eruption, and spectroscopy of light echoes has recently revealed extremely fast ejecta during the 1840s that indicate an explosive event. Were those previous eruptions explosive as well? If so, were they as energetic, did they also have such fast ejecta, and did they have the same geometry? The structure and excitation of the Outer Ejecta hold unique clues for reconstructing Eta Car's violent mass loss history. The locations of shock fronts in circumstellar material provide critical information, because they identify past discontinuities in the mass loss. This is one of the only ways to investigate the long term (i.e. centuries) evolution and duty cycle of eruptive mass loss in the most massive stars.

BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment

PubMed Central

Hsu, Ying; Kim, Gunhee; Zhang, Qihong; Datta, Poppy; Seo, Seongjin

2017-01-01

Genetic mutations disrupting the structure and function of primary cilia cause various inherited retinal diseases in humans. Bardet-Biedl syndrome (BBS) is a genetically heterogeneous, pleiotropic ciliopathy characterized by retinal degeneration, obesity, postaxial polydactyly, intellectual disability, and genital and renal abnormalities. To gain insight into the mechanisms of retinal degeneration in BBS, we developed a congenital knockout mouse of Bbs8, as well as conditional mouse models in which function of the BBSome (a protein complex that mediates ciliary trafficking) can be temporally inactivated or restored. We demonstrate that BBS mutant mice have defects in retinal outer segment morphogenesis. We further demonstrate that removal of Bbs8 in adult mice affects photoreceptor function and disrupts the structural integrity of the outer segment. Notably, using a mouse model in which a gene trap inhibiting Bbs8 gene expression can be removed by an inducible FLP recombinase, we show that when BBS8 is restored in immature retinas with malformed outer segments, outer segment extension can resume normally and malformed outer segment discs are displaced distally by normal outer segment structures. Over time, the retinas of the rescued mice become morphologically and functionally normal, indicating that there is a window of plasticity when initial retinal outer segment morphogenesis defects can be ameliorated. PMID:29049287

Erosion resistant elbow for solids conveyance

DOEpatents

Everett, J.W.

1984-10-23

An elbow and process for fabrication for use in particulate material conveyancing comprises a curved outer pipe, a curved inner pipe having the same radius of curvature as the outer pipe, concentric with and internal to the outer pipe, comprising an outer layer comprised of a first material and an inner layer comprised of a second material wherein said first material is characterized by high erosion resistance when impinged by particulate material and wherein said second material is characterized by high tensile strength and flexibility, and an inner pipe supporting means for providing support to said inner pipe, disposed between said inner pipe and said outer pipe. 4 figs.

Erosion resistant elbow for solids conveyance

DOEpatents

Everett, James W.

1984-10-23

An elbow and process for fabrication for use in particulate material conveyancing comprising a curved outer pipe, a curved inner pipe having the same radius of curvature as the outer pipe, concentric with and internal to the outer pipe, comprising an outer layer comprised of a first material and an inner layer comprised of a second material wherein said first material is characterized by high erosion resistance when impinged by particulate material and wherein said second material is characterized by high tensile strength and flexibility, and an inner pipe supporting means for providing support to said inner pipe, disposed between said inner pipe and said outer pipe.

Erosion resistant elbow for solids conveyance

DOEpatents

Not Available

An elvow and process for fabrication for use in particulate material conveying comprising a curved outer pipe, a curved inner pipe having the same radius of curvature as the outer pipe, concentric with and internal to the outer pipe, comprising an outer layer comprised of a first material and an inner layer comprised of a second material wherein said first material is characterized by high erosion resistance when impinged by particulate material and wherein said second material is characterized by high tensile strength and flexibility, and an inner pipe supporting means for providing support to said inner pipe, disposed between said inner pipe and said outer pipe. 4 figures.

Performance and component frontal areas of a hypothetical two-spool turbojet engine for three modes of operation

NASA Technical Reports Server (NTRS)

Dugan, James F , Jr

1955-01-01

Engine performance is better for constant outer-spool mechanical-speed operation than for constant inner-spool mechanical-speed operation over most of the flight range considered. Combustor and afterburner frontal areas are about the same for the two modes. Engine performance for a mode characterized by a constant outer-spool equivalent speed over part of the flight range and a constant outer-spool mechanical speed over the rest of the flight range is better that that for constant outer-spool mechanical speed operation. The former mode requires larger outer-spool centrifugal stresses and larger component frontal areas.

Methods and systems to facilitate reducing NO.sub.x emissions in combustion systems

DOEpatents

Lacy, Benjamin Paul [Greer, SC; Kraemer, Gilbert Otto [Greer, SC; Varatharajan, Balachandar [Clifton Park, NY; Yilmaz, Ertan [Albany, NY; Lipinski, John Joseph [Simpsonville, SC; Ziminsky, Willy Steve [Simpsonville, SC

2011-02-15

A method for assembling a gas turbine combustor system is provided. The method includes providing a combustion liner including a center axis, an outer wall, a first end, and a second end. The outer wall is orientated substantially parallel to the center axis. The method also includes coupling a transition piece to the liner second end. The transition piece includes an outer wall. The method further includes coupling a plurality of lean-direct injectors along at least one of the liner outer wall and the transition piece outer wall such that the injectors are spaced axially apart along the wall.

Peaceful Use of Outer Space: principles of Japanese Policies on Utilization and Activities in Outer space

NASA Astrophysics Data System (ADS)

Kosuge, Toshio

2002-01-01

" P e aceful use of outer space of outer space.....Principles of exploitation of outer space was passed in the Japanese Diet. It clearly mentioned that any activity of launching space object into outer space and developing launching rocket should be exclusively for peaceful purpose. NASDA was also established based upon the same principles of the public law. Japanese interpretation of Space Treaty and other related international agreements has been more strict on peaceful use of outer space, like non-military use rather than non-aggressive, because of influence of Japanese Constitution. Treaty and other agreements is analyzed through rapid development of its space activities, technologies and international cooperation with other space powers. Through more than thirty years experiences in space activities in public and private sectors, Japanese domestic laws and policies have not been changed in relation with basic principles. and laws relating to space activities in order to develop new space law and more international cooperation for space utilization rather than military use in new century.

Protein targeting and integration signal for the chloroplastic outer envelope membrane.

PubMed Central

Li, H M; Chen, L J

1996-01-01

Most proteins in chloroplasts are encoded by the nuclear genome and synthesized in the cytosol. With the exception of most quter envelope membrane proteins, nuclear-encoded chloroplastic proteins are synthesized with N-terminal extensions that contain the chloroplast targeting information of these proteins. Most outer membrane proteins, however, are synthesized without extensions in the cytosol. Therefore, it is not clear where the chloroplastic outer membrane targeting information resides within these polypeptides. We have analyzed a chloroplastic outer membrane protein, OEP14 (outer envelope membrane protein of 14 kD, previously named OM14), and localized its outer membrane targeting and integration signal to the first 30 amino acids of the protein. This signal consists of a positively charged N-terminal portion followed by a hydrophobic core, bearing resemblance to the signal peptides of proteins targeted to the endoplasmic reticulum. However, a chimeric protein containing this signal fused to a passenger protein did not integrate into the endoplasmic reticulum membrane. Furthermore, membrane topology analysis indicated that the signal inserts into the chloroplastic outer membrane in an orientation opposite to that predicted by the "positive inside" rule. PMID:8953775

Method of Fabricating Protective Coating for a Crucible with the Coating Having Channels Formed Therein

NASA Technical Reports Server (NTRS)

Grugel, Richard N. (Inventor)

2004-01-01

A method is provided for the fabrication of a protective coating for a crucible with channels being formed in the coating. A material is adhered to the outer wall of the crucible to form a pattern thereon. The outer wall of the crucible along with the pattern of material adhered thereto is next coated with another material. The material used to form the pattern should extend through the outer material coating to define at least one port therein. Next, the crucible with its pattern of material and outer coating material is heated to a temperature of transformation at which the pattern of material is transformed to a fluidic state while the crucible and outer coating material maintain their solid integrity. Such transformation could also be accomplished by using a solvent that causes the pattern of material to dissolve. Finally, the material in its fluidic state is removed via the at least one port formed in the outer material coating thereby leaving channels defined in the coating adjacent the outer wall of the crucible.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Du, Xinyu; Xu, Ye; Yang, Ji

The lack of arm tracers, especially remote tracers, is one of the most difficult problems preventing us from studying the structure of the Milky Way. Fortunately, with its high-sensitivity CO survey, the Milky Way Imaging Scroll Painting (MWISP) project offers such an opportunity. Since completing about one-third of its mission, an area of l = [100, 150]°, b = [−3, 5]° has nearly been covered. The Outer arm of the Milky Way first clearly revealed its shape in the second galactic quadrant in the form of molecular gas—this is the first time that the Outer arm has been reported inmore » such a large-scale mapping of molecular gas. Using the 115 GHz {sup 12}CO(1–0) data of MWISP at the LSR velocity ≃[−100, −60] km s{sup −1} and in the area mentioned above, we have detected 481 molecular clouds in total, and among them 332 (about 69%) are newly detected and 457 probably belong to the Outer arm. The total mass of the detected Outer arm clouds is ∼3.1 × 10{sup 6} M {sub ⊙}. Assuming that the spiral arm is a logarithmic spiral, the pitch angle is fitted as ∼13.°1. Besides combining both the CO data from MWISP and the 21 cm H i data from the Canadian Galactic Plane Survey (CGPS), the gas distribution, warp, and thickness of the Outer arm are also studied.« less

State dynamics of a double sandbar system

NASA Astrophysics Data System (ADS)

Price, T. D.; Ruessink, B. G.

2011-04-01

A 9.3-year dataset of low-tide time-exposure images from Surfers Paradise, Northern Gold Coast, Australia was used to characterise the state dynamics of a double sandbar system. The morphology of the nearshore sandbars was described by means of the sequential bar state classification scheme of Wright and Short [1984. Morphodynamic variability of surf zones and beaches: a synthesis. Marine Geology 56, 93-118]. Besides the two end members (the dissipative (D) and the reflective (R) states) and the four intermediate states (longshore bar and trough (LBT), rhythmic bar and beach (RBB), transverse bar and rip (TBR) and low tide terrace (LTT)), we identified two additional intermediate bar states. The erosive transverse bar and rip (eTBR) state related to the dominant oblique angle of wave incidence at the study site and the rhythmic low tide terrace (rLTT) related to the multiple bar setting. Using the alongshore barline variability and alongshore trough continuity as morphological indicators enabled the objective classification of the inner and outer bar states from the images. The outer bar was mostly in the TBR state and generally advanced sequentially through the states LBT-RBB-TBR-eTBR-LBT, with occasional transitions to the D state. Wave events led to abrupt state transitions of the outer bar, but, in contrast to expectations, did not necessarily correspond to upstate transitions. Instead, upstate (downstate) transitions coincided with angles of wave incidence θ larger (smaller) than 30°. The upstate TBR-eTBR-LBT sequence during high-angle events highlights the role of alongshore currents in bar straightening. The outer bar was found to govern the state of the inner bar to a large extent. Two types of inner bar behaviour were distinguished, based on the outer bar state. For intermediate outer bar states, the alongshore variability of the dominant inner rLTT state (52% in time) mainly related to that of the outer bar, implying some sort of morphological coupling. For dissipative outer bar states, however, the more upstate inner bar frequently separated from the shoreline and persistently developed rip channels as TBR became the most frequent state (60% in time).

Localization of the calcium channel subunits Cav1.2 (alpha1C) and Cav2.3 (alpha1E) in the mouse organ of Corti.

PubMed

Waka, N; Knipper, M; Engel, J

2003-10-01

Voltage-activated Ca2+ channels play an important role in synaptic transmission, signal processing and development. The immunohistochemical localization of Cav1.2 (alpha1C) and Cav2.3 (alpha1E) Ca2+ channels was studied in the developing and adult mouse organ of Corti using subunit-specific antibodies and fluorescent secondary antibodies with cochlear cryosections. Cav1.2 immunoreactivity has been detected from postnatal day 14 (P14) onwards at the synapses between cholinergic medial efferents and outer hair cells as revealed by co-staining with anti-synaptophysin and anti-choline acetyltransferase. Most likely the Cav1.2 immunoreactivity was located presynaptically at the site of contact of the efferent bouton with the outer hair cell which suggests a role for class C L-type Ca2+ channels in synaptic transmission of the medial efferent system. The localization of the second Ca2+ channel tested, Cav2.3, showed a pronounced change during cochlear development. From P2 until P10, Cav2.3 immunoreactivity was found in the outer spiral bundle followed by the inner spiral bundle, efferent endings and by medial efferent fibers. Around P14, Cav2.3 immunoreactivity disappeared from these structures and from P19 onwards it was observed in the basal poles of the outer hair cell membranes.

30 CFR 256.0 - Authority for information collection.

Code of Federal Regulations, 2010 CFR

2010-07-01

... OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and... part 256, Leasing of Sulphur or Oil and Gas in the Outer Continental Shelf.” (b) MMS collects this...

Drug discovery strategies to outer membrane targets in Gram-negative pathogens.

PubMed

Brown, Dean G

2016-12-15

This review will cover selected recent examples of drug discovery strategies which target the outer membrane (OM) of Gram-negative bacteria either by disruption of outer membrane function or by inhibition of essential gene products necessary for outer membrane assembly. Significant advances in pathway elucidation, structural biology and molecular inhibitor designs have created new opportunities for drug discovery within this target-class space. Copyright © 2016 Elsevier Ltd. All rights reserved.

System to control contamination during retrieval of buried TRU waste

DOEpatents

Menkhaus, Daniel E.; Loomis, Guy G.; Mullen, Carlan K.; Scott, Donald W.; Feldman, Edgar M.; Meyer, Leroy C.

1993-01-01

A system to control contamination during the retrieval of hazardous waste comprising an outer containment building, an inner containment building, within the outer containment building, an electrostatic radioactive particle recovery unit connected to and in communication with the inner and outer containment buildings, and a contaminate suppression system including a moisture control subsystem, and a rapid monitoring system having the ability to monitor conditions in the inner and outer containment buildings.

System to control contamination during retrieval of buried TRU waste

DOEpatents

Menkhaus, D.E.; Loomis, G.G.; Mullen, C.K.; Scott, D.W.; Feldman, E.M.; Meyer, L.C.

1993-04-20

A system is described to control contamination during the retrieval of hazardous waste comprising an outer containment building, an inner containment building, within the outer containment building, an electrostatic radioactive particle recovery unit connected to and in communication with the inner and outer containment buildings, and a contaminate suppression system including a moisture control subsystem, and a rapid monitoring system having the ability to monitor conditions in the inner and outer containment buildings.

Thrust rollers

NASA Technical Reports Server (NTRS)

Vranish, John M. (Inventor)

2007-01-01

A thrust roller bearing system comprising an inner rotating member, an outer rotating member and multiple rollers coupling the inner rotating member with outer rotating member. The inner and outer rotating members include thrust lips to enable the rollers to act as thrust rollers. The rollers contact inner and outer rotating members at bearing contact points along a contact line. Consequently, the radial/tilt and thrust forces move synchronously and simultaneously to create a bearing action with no slipping.

Orthogonally referenced integrated ensemble for navigation and timing

DOEpatents

Smith, Stephen Fulton; Moore, James Anthony

2013-02-26

An orthogonally referenced integrated ensemble for navigation and timing includes a dual-polyhedral oscillator array, including an outer sensing array of oscillators and an inner clock array of oscillators situated inside the outer sensing array. The outer sensing array includes a first pair of sensing oscillators situated along a first axis of the outer sensing array, a second pair of sensing oscillators situated along a second axis of the outer sensing array, and a third pair of sensing oscillators situated along a third axis of the outer sensing array. The inner clock array of oscillators includes a first pair of clock oscillators situated along a first axis of the inner clock array, a second pair of clock oscillators situated along a second axis of the inner clock array, and a third pair of clock oscillators situated along a third axis of the inner clock array.

Coaxial fuel and air premixer for a gas turbine combustor

DOEpatents

York, William D; Ziminsky, Willy S; Lacy, Benjamin P

2013-05-21

An air/fuel premixer comprising a peripheral wall defining a mixing chamber, a nozzle disposed at least partially within the peripheral wall comprising an outer annular wall spaced from the peripheral wall so as to define an outer air passage between the peripheral wall and the outer annular wall, an inner annular wall disposed at least partially within and spaced from the outer annular wall, so as to define an inner air passage, and at least one fuel gas annulus between the outer annular wall and the inner annular wall, the at least one fuel gas annulus defining at least one fuel gas passage, at least one air inlet for introducing air through the inner air passage and the outer air passage to the mixing chamber, and at least one fuel inlet for injecting fuel through the fuel gas passage to the mixing chamber to form an air/fuel mixture.

Containers and systems for the measurement of radioactive gases and related methods

DOEpatents

Mann, Nicholas R; Watrous, Matthew G; Oertel, Christopher P; McGrath, Christopher A

2017-06-20

Containers for a fluid sample containing a radionuclide for measurement of radiation from the radionuclide include an outer shell having one or more ports between an interior and an exterior of the outer shell, and an inner shell secured to the outer shell. The inner shell includes a detector receptacle sized for at least partial insertion into the outer shell. The inner shell and outer shell together at least partially define a fluid sample space. The outer shell and inner shell are configured for maintaining an operating pressure within the fluid sample space of at least about 1000 psi. Systems for measuring radioactivity in a fluid include such a container and a radiation detector received at least partially within the detector receptacle. Methods of measuring radioactivity in a fluid sample include maintaining a pressure of a fluid sample within a Marinelli-type container at least at about 1000 psi.

Orthogonally referenced integrated ensemble for navigation and timing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Stephen Fulton; Moore, James Anthony

2014-04-01

An orthogonally referenced integrated ensemble for navigation and timing includes a dual-polyhedral oscillator array, including an outer sensing array of oscillators and an inner clock array of oscillators situated inside the outer sensing array. The outer sensing array includes a first pair of sensing oscillators situated along a first axis of the outer sensing array, a second pair of sensing oscillators situated along a second axis of the outer sensing array, and a third pair of sensing oscillators situated along a third axis of the outer sensing array. The inner clock array of oscillators includes a first pair of clockmore » oscillators situated along a first axis of the inner clock array, a second pair of clock oscillators situated along a second axis of the inner clock array, and a third pair of clock oscillators situated along a third axis of the inner clock array.« less

Two-axis tracker for solar panels and the like

DOEpatents

Liao, Henry H.

2013-04-16

A tracker including an outer post having elongated bore and a lower end mounted on a sub-structure, an inner pole rotatably received in the elongated bore, a lower bearing in the bore adjacent a lower end of the outer post and attached thereto to be constrained from lateral movement and mounted on the sub-structure such that a lower end of the inner pole rests on and is supported by the lower bearing, an upper bearing near an upper end of the outer post, a circumferential drive supported on the outer post for rotating the inner pole relative to the outer post, such that substantially a full weight of a load on the inner pole is directly transmitted to the sub-structure and lateral force and torque leverage are placed on a full length of the outer post by way of the upper and lower bearing.

Outer Membrane Targeting of Passenger Proteins by the Vacuolating Cytotoxin Autotransporter of Helicobacter pylori

PubMed Central

Fischer, Wolfgang; Buhrdorf, Renate; Gerland, Elke; Haas, Rainer

2001-01-01

Helicobacter pylori produces a number of proteins associated with the outer membrane, including adhesins and the vacuolating cytotoxin. These proteins are supposed to integrate into the outer membrane by β-barrel structures, characteristic of the family of autotransporter proteins. By using the SOMPES (shuttle vector-based outer membrane protein expression) system for outer membrane protein production, we were able to functionally express in H. pylori the cholera toxin B subunit genetically fused to the C-terminal VacA domain. We demonstrate that the fusion protein is translocated to the H. pylori outer membrane and that the CtxB domain is exposed on the H. pylori surface. Thus, we provide the first experimental evidence that the C-terminal β-domain of VacA can transport a foreign passenger protein to the H. pylori surface and hence acts as a functional autotransporter. PMID:11598049

Axial flow positive displacement worm gas generator

NASA Technical Reports Server (NTRS)

Giffin, Rollin George (Inventor); Fakunle, Oladapo (Inventor); Murrow, Kurt David (Inventor)

2010-01-01

An axial flow positive displacement engine has an inlet axially spaced apart and upstream from an outlet. Inner and outer bodies have offset inner and outer axes extend from the inlet to the outlet through first, second, and third sections of a core assembly in serial downstream flow relationship. At least one of the bodies is rotatable about its axis. The inner and outer bodies have intermeshed inner and outer helical blades wound about the inner and outer axes respectively. The inner and outer helical blades extend radially outwardly and inwardly respectively. The helical blades have first, second, and third twist slopes in the first, second, and third sections respectively. The first twist slopes are less than the second twist slopes and the third twist slopes are less than the second twist slopes. A combustor section extends axially downstream through at least a portion of the second section.

Axial flow positive displacement worm compressor

NASA Technical Reports Server (NTRS)

Murrow, Kurt David (Inventor); Giffin, Rollin George (Inventor); Fakunle, Oladapo (Inventor)

2010-01-01

An axial flow positive displacement compressor has an inlet axially spaced apart and upstream from an outlet. Inner and outer bodies have offset inner and outer axes extend from the inlet to the outlet through first and second sections of a compressor assembly in serial downstream flow relationship. At least one of the bodies is rotatable about its axis. The inner and outer bodies have intermeshed inner and outer helical blades wound about the inner and outer axes respectively. The inner and outer helical blades extend radially outwardly and inwardly respectively. The helical blades have first and second twist slopes in the first and second sections respectively. The first twist slopes are less than the second twist slopes. An engine including the compressor has in downstream serial flow relationship from the compressor a combustor and a high pressure turbine drivingly connected to the compressor by a high pressure shaft.

Lubrication of 35-millimeter-bore ball bearings of several designs to 2.5 million DN

NASA Technical Reports Server (NTRS)

Schuller, F. T.

1983-01-01

Parametric tests were conducted with 35mm bore, angular contact ball bearings with either a single or double outer and guided cage. The bearings were either lubricated by oil jets or employed inner ring lubrication. Outer ring cooling was added in selected tests. Lubricant flow to the bearing ranged from 300 to 1900 cc/min. All bearings were successfully run at speeds to 2.5 million DN. Increasing the lubricant flow decreased bearing ring temperatures but increased bearing power lines. The power loss and race temperatures of a jet lubricated with double outer land guided cage were always higher than those of the single land guided design at similar test conditions. The lowest bearing operating temperatures were achieved when inner ring lubrication and outer ring cooling were combined. It is found that cage slip of a double outer land guided cage is approximately twice that of a single outer land guided cage.

Torque command steering law for double-gimbaled control moment gyros applied to rotor energy storage

NASA Technical Reports Server (NTRS)

Kennel, H. F.

1984-01-01

A steering law is presented which has all the features required for space applications, assuming the CMG outer gimbal freedom is unlimited. The reason is the idea of mounting all the outer gimbal axes of the CMGs parallel to each other. This allows the decomposition of the steering law problem into a linear one for the inner gimbal angle rates and a planar one for the outer gimbal angle rates. The inner gimbal angle rates are calculated first, since they are not affected by the outer gimbal angle rates. For the calculation of the outer rates, the inner rates are then known quantities. An outer gimbal angle distribution function (to avoid singularities internal to the total angular momentum envelope) generates distribution rates next, and finally the pseudoinverse method is used to insure that the desired total torque is delivered.

Lateral release of proteins from the TOM complex into the outer membrane of mitochondria.

PubMed

Harner, Max; Neupert, Walter; Deponte, Marcel

2011-07-15

The TOM complex of the outer membrane of mitochondria is the entry gate for the vast majority of precursor proteins that are imported into the mitochondria. It is made up by receptors and a protein conducting channel. Although precursor proteins of all subcompartments of mitochondria use the TOM complex, it is not known whether its channel can only mediate passage across the outer membrane or also lateral release into the outer membrane. To study this, we have generated fusion proteins of GFP and Tim23 which are inserted into the inner membrane and, at the same time, are spanning either the TOM complex or are integrated into the outer membrane. Our results demonstrate that the TOM complex, depending on sequence determinants in the precursors, can act both as a protein conducting pore and as an insertase mediating lateral release into the outer membrane.

Otoscopic examinations reveal high prevalence of outer and middle ear pathologies in paediatrics in Limpopo, South Africa.

PubMed

Phanguphangu, Mukovhe Chad

2017-04-01

To determine the prevalence of outer and middle ear pathologies in paediatrics in Limpopo, South Africa. Cross-sectional retrospective review of otoscopy results obtained during a school health screening campaign conducted between March and June 2015. Descriptive statistics through percentages and frequency tables were used to analyse the data. Logistic regression was used to determine associations between age, gender and pathologies observed. Medical folders of 1089 pupils. Forty-nine percent had normal otoscopy results. A significant 36% (n = 392) had impacted cerumen. Furthermore, 45% of those with impacted cerumen were bilaterally impacted. Additionally, 4% presented with foreign bodies and a further 8% had otitis externa and otitis media. The remaining 3% had tympanic membrane perforations. The odds of developing outer and middle ear pathologies were higher in pupils below 6 years of age (p = 0.046). This study highlights a high prevalence of outer and middle ear pathologies in paediatrics in Limpopo and therefore recommends comprehensive baseline and periodic screenings; to identify children with outer and middle ear pathologies and need further management, and consequently prevent the complications of these pathologies. Additionally, this report highlights a rising need for large-scale research to provide comprehensive analysis of these pathologies.

The Effects of Forming Parameters on Conical Ring Rolling Process

PubMed Central

Meng, Wen; Zhao, Guoqun; Guan, Yanjin

2014-01-01

The plastic penetration condition and biting-in condition of a radial conical ring rolling process with a closed die structure on the top and bottom of driven roll, simplified as RCRRCDS, were established. The reasonable value range of mandrel feed rate in rolling process was deduced. A coupled thermomechanical 3D FE model of RCRRCDS process was established. The changing laws of equivalent plastic strain (PEEQ) and temperature distributions with rolling time were investigated. The effects of ring's outer radius growth rate and rolls sizes on the uniformities of PEEQ and temperature distributions, average rolling force, and average rolling moment were studied. The results indicate that the PEEQ at the inner layer and outer layer of rolled ring are larger than that at the middle layer of ring; the temperatures at the “obtuse angle zone” of ring's cross-section are higher than those at “acute angle zone”; the temperature at the central part of ring is higher than that at the middle part of ring's outer surfaces. As the ring's outer radius growth rate increases at its reasonable value ranges, the uniformities of PEEQ and temperature distributions increase. Finally, the optimal values of the ring's outer radius growth rate and rolls sizes were obtained. PMID:25202716

Guidance and navigation requirements for unmanned flyby and swingby missions to the outer planets. Volume 2: impulsive high thrust missions, phase A

NASA Technical Reports Server (NTRS)

1969-01-01

The impulsive, high thrust missions portion of a study on guidance and navigation requirements for unmanned flyby and swingby missions to the outer planet is presented. The proper balance between groundbased navigational capability, using the deep space network (DSN) alone, and an onboard navigational capability with and without supplemental use of DSN tracking, for unmanned missions to the outer planets of the solar system is defined. A general guidance and navigation requirements program is used to survey parametrically the characteristics associated with three types of navigation systems: (1) totally onboard, (2) totally Earth-based, and (3) a combination of these two.

Anatomical correlates to the bands seen in the outer retina by optical coherence tomography: literature review and model.

PubMed

Spaide, Richard F; Curcio, Christine A

2011-09-01

To evaluate the validity of commonly used anatomical designations for the four hyperreflective outer retinal bands seen in current-generation optical coherence tomography, a scale model of outer retinal morphology was created using published information for direct comparison with optical coherence tomography scans. Articles and books concerning histology of the outer retina from 1900 until 2009 were evaluated, and data were used to create a scale model drawing. Boundaries between outer retinal tissue compartments described by the model were compared with intensity variations of representative spectral-domain optical coherence tomography scans using longitudinal reflectance profiles to determine the region of origin of the hyperreflective outer retinal bands. This analysis showed a high likelihood that the spectral-domain optical coherence tomography bands attributed to the external limiting membrane (the first, innermost band) and to the retinal pigment epithelium (the fourth, outermost band) are correctly attributed. Comparative analysis showed that the second band, often attributed to the boundary between inner and outer segments of the photoreceptors, actually aligns with the ellipsoid portion of the inner segments. The third band corresponded to an ensheathment of the cone outer segments by apical processes of the retinal pigment epithelium in a structure known as the contact cylinder. Anatomical attributions and subsequent pathophysiologic assessments pertaining to the second and third outer retinal hyperreflective bands may not be correct. This analysis has identified testable hypotheses for the actual correlates of the second and third bands. Nonretinal pigment epithelium contributions to the fourth band (e.g., Bruch membrane) remain to be determined.

A likely planet-induced gap in the disc around T Cha

NASA Astrophysics Data System (ADS)

Hendler, Nathanial P.; Pinilla, Paola; Pascucci, Ilaria; Pohl, Adriana; Mulders, Gijs; Henning, Thomas; Dong, Ruobing; Clarke, Cathie; Owen, James; Hollenbach, David

2018-03-01

We present high-resolution (0.11 × 0.06 arcsec2) 3 mm ALMA observations of the highly inclined transition disc around the star T Cha. Our continuum image reveals multiple dust structures: an inner disc, a spatially resolved dust gap, and an outer ring. When fitting sky-brightness models to the real component of the 3 mm visibilities, we infer that the inner emission is compact (≤1 au in radius), the gap width is between 18 and 28 au, and the emission from the outer ring peaks at ˜36 au. We compare our ALMA image with previously published 1.6 μm VLT/SPHERE imagery. This comparison reveals that the location of the outer ring is wavelength dependent. More specifically, the peak emission of the 3 mm ring is at a larger radial distance than that of the 1.6 μm ring, suggesting that millimeter-sized grains in the outer disc are located farther away from the central star than micron-sized grains. We discuss different scenarios to explain our findings, including dead zones, star-driven photoevaporation, and planet-disc interactions. We find that the most likely origin of the dust gap is from an embedded planet, and estimate - for a single planet scenario - that T Cha's gap is carved by a 1.2MJup planet.

Cosmological perturbations in the (1 + 3 + 6)-dimensional space-times

NASA Astrophysics Data System (ADS)

Tomita, K.

2014-12-01

Cosmological perturbations in the (1+3+6)-dimensional space-times including photon gas without viscous processes are studied on the basis of Abbott et al.'s formalism [R. B. Abbott, B. Bednarz, and S. D. Ellis, Phys. Rev. D 33, 2147 (1986)]. Space-times consist of outer space (the 3-dimensional expanding section) and inner space (the 6-dimensional section). The inner space expands initially and later contracts. Abbott et al. derived only power-type solutions, which appear at the final stage of the space-times, in the small wave-number limit. In this paper, we derive not only small wave-number solutions, but also large wave-number solutions. It is found that the latter solutions depend on the two wave-numbers k_r and k_R (which are defined in the outer and inner spaces, respectively), and that the k_r-dependent and k_R-dependent parts dominate the total perturbations when (k_r/r(t))/(k_R/R(t)) ≫ 1 or ≪ 1, respectively, where r(t) and R(t) are the scale-factors in the outer and inner spaces. By comparing the behaviors of these perturbations, moreover, changes in the spectrum of perturbations in the outer space with time are discussed.

Outer Space Treaty Signed in Moscow (1967)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Various shots of the representatives of various countries signing the outer space treaty in Moscow. Various shots as the 'big 3' sign the agreement - Mr Andrei Gromyko for Russia, then British Ambassador Sir Geoffrey Harrison for Britain and American Ambassador Llewllyn Thompson for America. Prime Minister of USSR Alexei Kosygin stands behind and watches events. They address the assembly after signing.

pF3D Simulations of Large Outer-Beam Brillouin Scattering from NIF Rugby Hohlraums

NASA Astrophysics Data System (ADS)

Langer, Steven; Strozzi, David; Chapman, Thomas; Amendt, Peter

2015-11-01

We assess the cause of large outer-beam stimulated Brillouin scattering (SBS) in a NIF shot with a rugby-shaped hohlraum, which has less wall surface loss and thus higher x-ray drive than a cylindrical hohlraum of the same radius. This shot differed from a prior rugby shot with low SBS in three ways: outer beam pointing, split-pointing of the four beams within each outer-beam quadruplet, and a small amount of neon added to the hohlraum helium fill gas. We use pF3D, a massively-parallel, paraxial-envelope laser plasma interaction code, with plasma profiles from the radiation-hydrodynamics code Lasnex. We determine which change between the two shots increased the SBS by adding them one at a time to the simulations. We compare the simulations to experimental data for total SBS power, its spatial distribution at the lens, and the SBS spectrum. For each shot, we use profiles from Lasnex simulations with and without a model for mix at the hohlraum wall-gas interface. Work performed under the auspices of the U.S. Department of Energy by LLNL under Contract DE-AC52-07NA27344. Release number LLNL-ABS-674893.

The Dynamics of Tightly-packed Planetary Systems in the Presence of an Outer Planet: Case Studies Using Kepler-11 and Kepler-90

NASA Astrophysics Data System (ADS)

Granados Contreras, A. P.; Boley, A. C.

2018-03-01

We explore the effects of an undetected outer giant planet on the dynamics, observability, and stability of Systems with Tightly-packed Inner Planets (STIPs). We use direct numerical simulations along with secular theory and synthetic secular frequency spectra to analyze how analogues of Kepler-11 and Kepler-90 behave in the presence of a nearly co-planar, Jupiter-like outer perturber with semimajor axes between 1 and 5.2 au. Most locations of the outer perturber do not affect the evolution of the inner planetary systems, apart from altering precession frequencies. However, there are locations at which an outer planet causes system instability due to, in part, secular eccentricity resonances. In Kepler-90, there is a range of orbital distances for which the outer perturber drives planets b and c, through secular interactions, onto orbits with inclinations that are ∼16° away from the rest of the planets. Kepler-90 is stable in this configuration. Such secular resonances can thus affect the observed multiplicity of transiting systems. We also compare the synthetic apsidal and nodal precession frequencies with the secular theory and find some misalignment between principal frequencies, indicative of strong interactions between the planets (consistent with the system showing TTVs). First-order libration angles are calculated to identify MMRs in the systems, for which two near-MMRs are shown in Kepler-90, with a 5:4 between b and c, as well as a 3:2 between g and h.

Two passive mechanical conditions modulate power generation by the outer hair cells

PubMed Central

Gracewski, Sheryl M.

2017-01-01

In the mammalian cochlea, small vibrations of the sensory epithelium are amplified due to active electro-mechanical feedback of the outer hair cells. The level of amplification is greater in the base than in the apex of the cochlea. Theoretical studies have used longitudinally varying active feedback properties to reproduce the location-dependent amplification. The active feedback force has been considered to be proportional to the basilar membrane displacement or velocity. An underlying assumption was that organ of Corti mechanics are governed by rigid body kinematics. However, recent progress in vibration measurement techniques reveals that organ of Corti mechanics are too complicated to be fully represented with rigid body kinematics. In this study, two components of the active feedback are considered explicitly—organ of Corti mechanics, and outer hair cell electro-mechanics. Physiological properties for the outer hair cells were incorporated, such as the active force gain, mechano-transduction properties, and membrane RC time constant. Instead of a kinematical model, a fully deformable 3D finite element model was used. We show that the organ of Corti mechanics dictate the longitudinal trend of cochlear amplification. Specifically, our results suggest that two mechanical conditions are responsible for location-dependent cochlear amplification. First, the phase of the outer hair cell’s somatic force with respect to its elongation rate varies along the cochlear length. Second, the local stiffness of the organ of Corti complex felt by individual outer hair cells varies along the cochlear length. We describe how these two mechanical conditions result in greater amplification toward the base of the cochlea. PMID:28880884

Calcium homeostasis in the outer segments of retinal rods from the tiger salamander.

PubMed Central

Lagnado, L; Cervetto, L; McNaughton, P A

1992-01-01

1. The processes regulating intracellular calcium in the outer segments of salamander rods have been investigated. The main preparation used was the isolated rod loaded with the Ca(2+)-sensitive photoprotein aequorin, from which outer segment membrane current and free [Ca2+]i could be recorded simultaneously. Two other preparations were also used: outer segment membrane current was recorded from intact, isolated rods using a suction pipette, and from detached outer segments using a whole-cell pipette. 2. Measurements of free intracellular [Ca2+] in Ringer solution were obtained from two aequorin-loaded rods. Mean [Ca2+]i in darkness was 0.41 microM, and after a bright flash [Ca2+]i fell to below detectable levels ( < 0.3 microM). No release of intracellular Ca2+ by a bright flash of light could be detected ( < 0.2 microM). 3. Application of the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine (IBMX) caused an increase in the size of the light-sensitive current and a rise in [Ca2+]i, but application of IBMX either when the light-sensitive channels had been closed by a bright light or in the absence of external Ca2+ caused no detectable rise in [Ca2+]i. It is concluded that IBMX increases [Ca2+]i by opening light-sensitive channels, and does not release Ca2+ from stores within the outer segment. 4. Removal of external Na+ caused a rise in [Ca2+]i to around 2 microM and completely suppressed the light-sensitive current. 5. The Na(+)-Ca2+, K+ exchange current in aequorin-loaded rods was activated in first-order manner by internal free calcium, with a mean Michaelis constant, KCa, of 1.6 microM. 6. The KCa of the Na(+)-Ca2+, K+ exchange was increased by elevating internal [Na+]. 7. The Michaelis relation between [Ca2+]i and the activity of the Na(+)-Ca2+, K+ exchange was used to calculate the change in [Ca2+]i occurring during the response to a bright light. In aequorin-loaded rods in Ringer solution the mean change in free [Ca2+]i after a bright flash was 0.34 microM. In these rods 10% of the dark current was carried by Ca2+. 8. Most of the calcium entering the outer segment was taken up rapidly and reversibly by buffer systems. The time constant of equilibration between free and rapidly bound Ca2+ was less than 20 ms. No slow component of calcium uptake was detected. 9. Two components of calcium buffering could be distinguished in the outer segments of aequorin-loaded rods.(ABSTRACT TRUNCATED AT 400 WORDS) PMID:1282928

Injectors for Multipoint Injection

NASA Technical Reports Server (NTRS)

Prociw, Lev Alexander (Inventor); Ryon, Jason (Inventor)

2015-01-01

An injector for a multipoint combustor system includes an inner air swirler which defines an interior flow passage and a plurality of swirler inlet ports in an upstream portion thereof. The inlet ports are configured and adapted to impart swirl on flow in the interior flow passage. An outer air cap is mounted outboard of the inner swirler. A fuel passage is defined between the inner air swirler and the outer air cap, and includes a discharge outlet between downstream portions of the inner air swirler and the outer air cap for issuing fuel for combustion. The outer air cap defines an outer air circuit configured for substantially unswirled injection of compressor discharge air outboard of the interior flow passage.

Theory of nanotube faraday cage

NASA Astrophysics Data System (ADS)

Roxana Margine, Elena; Nisoli, Cristiano; Kolmogorov, Aleksey; Crespi, Vincent H.

2003-03-01

Charge transfer between dopants and double-wall carbon nanotubes is examined theoretically. We model the system as a triple cylindrical capacitor with the dopants forming a shell around the outer wall of the nanotube. The total energy of the system contains three terms: the band structure energies of the inner and outer tube, calculated in a tight-binding model with rigid bands, and the electrostatic energy of the tri-layer distribution. Even for metallic inner and outer tube walls, wherein the diameter dependence of the bandgap does not favor the outer wall, nearly all of the dopant charge resides on the outer layer, a nanometer-scale Faraday cage. The calculated charge distribution is in agreement with recent experimental measurements.

Corrugated outer sheath gas-insulated transmission line

DOEpatents

Kemeny, George A.; Cookson, Alan H.

1981-01-01

A gas-insulated transmission line includes two transmission line sections each of which are formed of a corrugated outer housing enclosing an inner high-voltage conductor disposed therein, with insulating support means supporting the inner conductor within the outer housing and an insulating gas providing electrical insulation therebetween. The outer housings in each section have smooth end sections at the longitudinal ends thereof which are joined together by joining means which provide for a sealing fixed joint.

Iodination of Escherichia coli with chloramine T: selective labeling of the outer membrane lipoprotein.

PubMed Central

Munford, R S; Gotschlich, E C

1977-01-01

Iodination of Escherichia coli cells with chloramine T preferentially labels the free and murein-bound forms of the outer membrane lipoprotein. Iodination for 15 s at 15 degrees C labels the two forms of the lipoprotein almost exclusively, whereas iodination for 60 s at 25 degrees C also labels the other major outer membrane proteins. Chloramine T iodination is a rapid, simple technique for labeling the outer membrane lipoprotein. PMID:400793

Kar5p is required for multiple functions in both inner and outer nuclear envelope fusion in Saccharomyces cerevisiae.

PubMed

Rogers, Jason V; Rose, Mark D

2014-12-02

During mating in the budding yeast Saccharomyces cerevisiae, two haploid nuclei fuse via two sequential membrane fusion steps. SNAREs (i.e., soluble N-ethylmaleimide-sensitive factor attachment protein receptors) and Prm3p mediate outer nuclear membrane fusion, but the inner membrane fusogen remains unknown. Kar5p is a highly conserved transmembrane protein that localizes adjacent to the spindle pole body (SPB), mediates nuclear envelope fusion, and recruits Prm3p adjacent to the SPB. To separate Kar5p's functions, we tested localization, Prm3p recruitment, and nuclear fusion efficiency in various kar5 mutants. All domains and the conserved cysteine residues were essential for nuclear fusion. Several kar5 mutant proteins localized properly but did not mediate Prm3p recruitment; other kar5 mutant proteins localized and recruited Prm3p but were nevertheless defective for nuclear fusion, demonstrating additional functions beyond Prm3p recruitment. We identified one Kar5p domain required for SPB localization, which is dependent on the half-bridge protein Mps3p. Electron microscopy revealed a kar5 mutant that arrests with expanded nuclear envelope bridges, suggesting that Kar5p is required after outer nuclear envelope fusion. Finally, a split-GFP assay demonstrated that Kar5p localizes to both the inner and outer nuclear envelope. These insights suggest a mechanism by which Kar5p mediates inner nuclear membrane fusion. Copyright © 2015 Rogers and Rose.

Kar5p Is Required for Multiple Functions in Both Inner and Outer Nuclear Envelope Fusion in Saccharomyces cerevisiae

PubMed Central

Rogers, Jason V.; Rose, Mark D.

2014-01-01

During mating in the budding yeast Saccharomyces cerevisiae, two haploid nuclei fuse via two sequential membrane fusion steps. SNAREs (i.e., soluble N-ethylmaleimide–sensitive factor attachment protein receptors) and Prm3p mediate outer nuclear membrane fusion, but the inner membrane fusogen remains unknown. Kar5p is a highly conserved transmembrane protein that localizes adjacent to the spindle pole body (SPB), mediates nuclear envelope fusion, and recruits Prm3p adjacent to the SPB. To separate Kar5p’s functions, we tested localization, Prm3p recruitment, and nuclear fusion efficiency in various kar5 mutants. All domains and the conserved cysteine residues were essential for nuclear fusion. Several kar5 mutant proteins localized properly but did not mediate Prm3p recruitment; other kar5 mutant proteins localized and recruited Prm3p but were nevertheless defective for nuclear fusion, demonstrating additional functions beyond Prm3p recruitment. We identified one Kar5p domain required for SPB localization, which is dependent on the half-bridge protein Mps3p. Electron microscopy revealed a kar5 mutant that arrests with expanded nuclear envelope bridges, suggesting that Kar5p is required after outer nuclear envelope fusion. Finally, a split-GFP assay demonstrated that Kar5p localizes to both the inner and outer nuclear envelope. These insights suggest a mechanism by which Kar5p mediates inner nuclear membrane fusion. PMID:25467943

Multimodal imaging in a case of bilateral outer retinitis associated with mumps infection.

PubMed

Kahloun, Rim; Ben Amor, Hager; Ksiaa, Imen; Zina, Sourour; Jelliti, Bechir; Ben Yahia, Salim; Khairallah, Moncef

2018-02-01

To report the results of multimodal imaging of acute outer retinitis associated to mumps infection. A patient with mumps-associated outer retinitis evaluated by color fundus photography, spectral domain optical coherence tomography (SD-OCT), optical coherence tomography angiography, fundus autofluorescence (FAF), fluorescein angiography (FA), and indocyanine green angiography (ICGA). We report a case of a 12-year-old boy who developed bilateral outer retinitis related to mumps. Ophthalmoscopy showed confluent areas of outer retinitis involving the posterior pole and the periphery with a centrifugal gyrate pattern. SD-OCT revealed a marked disorganization of the outer retinal layers with multiple highly reflective spicules. FA shows diffuse late hyperfluorescence with optic disk staining. ICGA shows macular and peripheral hyperfluorescent lesions with a geographical pattern in the late phases. The patient was treated with acyclovir and oral prednisone. Four weeks after presentation visual acuity remained unchanged, and retinal changes seen at the acute phase had resolved leading to extensive retinal atrophy and optic disk pallor. SD-OCT showed atrophy of the retinal pigment epithelial and outer retinal layers. FAF revealed scattered hyperautofluorescent lesions. Electrophysiology showed generalized retinal dysfunction. Mumps infection should be considered in the differential diagnosis of bilateral necrotizing outer retinitis in children and young adults. A multimodal imaging approach may help distinguish mumps-associated retinitis from other causes of viral retinitis and facilitate appropriate management.

The relationship between the plasmapause and outer belt electrons

DOE PAGES

Goldstein, J.; Baker, D. N.; Blake, J. B.; ...

2016-09-01

Here, we quantify the spatial relationship between the plasmapause and outer belt electrons for a 5 day period, 15–20 January 2013, by comparing locations of relativistic electron flux peaks to the plasmapause. A peak-finding algorithm is applied to 1.8–7.7 MeV relativistic electron flux data. A plasmapause gradient finder is applied to wave-derived electron number densities >10 cm –3. We identify two outer belts. Outer belt 1 is a stable zone of >3 MeV electrons located 1–2 R E inside the plasmapause. Outer belt 2 is a dynamic zone of <3 MeV electrons within 0.5 R E of the moving plasmapause.more » Electron fluxes earthward of each belt's peak are anticorrelated with cold plasma density. Belt 1 decayed on hiss timescales prior to a disturbance on 17 January and suffered only a modest dropout, perhaps owing to shielding by the plasmasphere. Afterward, the partially depleted belt 1 continued to decay at the initial rate. Belt 2 was emptied out by strong disturbance-time losses but restored within 24 h. For global context we use a plasmapause test particle simulation and derive a new plasmaspheric index F p, the fraction of a circular drift orbit inside the plasmapause. We find that the locally measured plasmapause is (for this event) a good proxy for the globally integrated opportunity for losses in cold plasma. Our analysis of the 15–20 January 2013 time interval confirms that high-energy electron storage rings can persist for weeks or even months if prolonged quiet conditions prevail. This case study must be followed up by more general study (not limited to a 5 day period).« less

The relationship between the plasmapause and outer belt electrons

NASA Astrophysics Data System (ADS)

Goldstein, J.; Baker, D. N.; Blake, J. B.; De Pascuale, S.; Funsten, H. O.; Jaynes, A. N.; Jahn, J.-M.; Kletzing, C. A.; Kurth, W. S.; Li, W.; Reeves, G. D.; Spence, H. E.

2016-09-01

We quantify the spatial relationship between the plasmapause and outer belt electrons for a 5 day period, 15-20 January 2013, by comparing locations of relativistic electron flux peaks to the plasmapause. A peak-finding algorithm is applied to 1.8-7.7 MeV relativistic electron flux data. A plasmapause gradient finder is applied to wave-derived electron number densities >10 cm-3. We identify two outer belts. Outer belt 1 is a stable zone of >3 MeV electrons located 1-2 RE inside the plasmapause. Outer belt 2 is a dynamic zone of <3 MeV electrons within 0.5 RE of the moving plasmapause. Electron fluxes earthward of each belt's peak are anticorrelated with cold plasma density. Belt 1 decayed on hiss timescales prior to a disturbance on 17 January and suffered only a modest dropout, perhaps owing to shielding by the plasmasphere. Afterward, the partially depleted belt 1 continued to decay at the initial rate. Belt 2 was emptied out by strong disturbance-time losses but restored within 24 h. For global context we use a plasmapause test particle simulation and derive a new plasmaspheric index Fp, the fraction of a circular drift orbit inside the plasmapause. We find that the locally measured plasmapause is (for this event) a good proxy for the globally integrated opportunity for losses in cold plasma. Our analysis of the 15-20 January 2013 time interval confirms that high-energy electron storage rings can persist for weeks or even months if prolonged quiet conditions prevail. This case study must be followed up by more general study (not limited to a 5 day period).

Temporal dynamics of stem expansion and contraction in savanna trees: withdrawal and recharge of stored water.

PubMed

Scholz, Fabian C; Bucci, Sandra J; Goldstein, Guillermo; Meinzer, Frederick C; Franco, Augusto C; Miralles-Wilhelm, Fernando

2008-03-01

Relationships between diel changes in stem expansion and contraction and discharge and refilling of stem water storage tissues were studied in six dominant Neotropical savanna (cerrado) tree species from central Brazil. Two stem tissues were studied, the active xylem or sapwood and the living tissues located between the cambium and the cork, made up predominantly of parenchyma cells (outer parenchyma). Outer parenchyma and sapwood density ranged from 320 to 410 kg m(-3) and from 420 to 620 kg m(-3), respectively, depending on the species. The denser sapwood tissues exhibited smaller relative changes in cross-sectional area per unit change in water potential compared with the outer parenchyma. Despite undergoing smaller relative changes in cross-sectional area, the sapwood released about 3.5 times as much stored water for a given change in area as the outer parenchyma. Cross-sectional area decreased earlier in the morning in the outer parenchyma than in the sapwood with lag times up to 30 min for most species. The relatively small lag time between dimensional changes of the two tissues suggested that they were hydraulically well connected. The initial morning increase in basal sap flow lagged about 10 to 130 min behind that of branch sap flow. Species-specific lag times between morning declines in branch and main stem cross-sectional area were a function of relative stem water storage capacity, which ranged from 16 to 31% of total diurnal water loss. Reliance on stored water to temporarily replace transpirational losses is one of the homeostatic mechanisms that constrain the magnitude of leaf water deficits in cerrado trees.

Prototype Moving Base Rotating Gravity Gradiometer

DTIC Science & Technology

1975-05-01

general similarity. Figure II-A-1-3 depicts the first step in disassembly. Number 1 points to the Stator or housing assembly, which in turn...mounts to an environmental isolation system. Number 2 points to the Outer Rotor which is supported within the Stator, at each end, by two journal...bear- ings (not shown). The Outer Rotor is rotated by two electric motors. Number 3 points to the "drag cup" component of each motor. Number 4

Atmospheric Mining in the Outer Solar System: Outer Planet In-Space Bases and Moon Bases for Resource Processing

NASA Technical Reports Server (NTRS)

Palaszewski, Bryan

2017-01-01

Atmospheric mining in the outer solar system has been investigated as a means of fuel production for high energy propulsion and power. Fusion fuels such as Helium 3 (3He) and deuterium can be wrested from the atmospheres of Uranus and Neptune and either returned to Earth or used in-situ for energy production. Helium 3 and deuterium were the primary gases of interest with hydrogen being the primary propellant for nuclear thermal solid core and gas core rocket-based atmospheric flight. A series of analyses were undertaken to investigate resource capturing aspects of atmospheric mining in the outer solar system. This included the gas capturing rate, storage options, and different methods of direct use of the captured gases. While capturing 3He, large amounts of hydrogen and 4He are produced. The propulsion and transportation requirements for all of the major moons of Uranus and Neptune are presented. Analyses of orbital transfer vehicles (OTVs), landers, factories, and the issues with in-situ resource utilization (ISRU) low gravity processing factories are included. Preliminary observations are presented on near-optimal selections of moon base orbital locations, OTV power levels, and OTV and lander rendezvous points. Several artificial gravity in-space base designs and orbital sites at Uranus and Neptune and the OTV requirements to support them are also addressed.

THE MECHANISM OF ACTION OF COLCHICINE

PubMed Central

Wilson, Leslie; Meza, Isaura

1973-01-01

The thermal depolymerization procedure of Stephens (1970. J. Mol. Biol. 47:353) has been employed for solubilization of Strongylocentrotus purpuratus sperm tail outer doublet microtubules with the use of a buffer during solubilization which is of optimal pH and ionic strength for the preservation of colchicine binding activity of chick embryo brain tubulin. Colchicine binding values were corrected for first-order decay during heat solubilization at 50°C (t½ = 5.4 min) and incubation with colchicine at 37°C in the presence of vinblastine sulfate (t½ = 485 min). The colchicine binding properties of heat-solubilized outer doublet tubulin were qualitatively identical with those of other soluble forms of tubulin. The solubilized tubulin (mol wt, 115,000) bound 0.9 ± 0.2 mol of colchicine per mol of tubulin, with a binding constant of 6.3 x 105 liters/mol at 37°C. The colchicine binding reaction was both time and temperature dependent, and the binding of colchicine was prevented in a competitive manner by podophyllotoxin (Ki = 1.3 x 10-6 M). The first-order decay of colchicine binding activity was substantially decreased by the addition of the vinca alkaloids, vinblastine sulfate or vincristine sulfate, thus demonstrating the presence of a vinca alkaloid binding site(s) on the outer doublet tubulin. Tubulin contained within the assembled microtubules did not decay. Intact outer doublet microtubules bound less than 0.001 mol of colchicine per mol of tubulin contained in the microtubules, under conditions where soluble tubulin would have bound 1 mol of colchicine per mol of tubulin (saturating concentration of colchicine, no decay of colchicine binding activity). The presence of colchicine had no effect on the rate of solubilization of outer doublet microtubules during incubation at 37°C. Therefore, the colchicine binding site on tubulin is blocked (not available to bind colchicine) when the tubulin is in the assembled outer doublet microtubules. PMID:4747924

The Width of a Solar Coronal Mass Ejection and the Source of the Driving Magnetic Explosion: A Test of the Standard Scenario for CME Production

NASA Technical Reports Server (NTRS)

Moore, Ronald L.; Sterling, Alphonse C.; Suess, Steven T.

2007-01-01

We show that the strength (B(sub F1are)) of the magnetic field in the area covered by the flare arcade following a CME-producing ejective solar eruption can be estimated from the final angular width (Final Theta(sub CME)) of the CME in the outer corona and the final angular width (Theta(sub Flare)) of the flare arcade: B(sub Flare) approx. equals 1.4[(Final Theta(sub CME)/Theta(sub Flare)] (exp 2)G. We assume (1) the flux-rope plasmoid ejected from the flare site becomes the interior of the CME plasmoid; (2) in the outer corona (R > 2 (solar radius)) the CME is roughly a "spherical plasmoid with legs" shaped like a lightbulb; and (3) beyond some height in or below the outer corona the CME plasmoid is in lateral pressure balance with the surrounding magnetic field. The strength of the nearly radial magnetic field in the outer corona is estimated from the radial component of the interplanetary magnetic field measured by Ulysses. We apply this model to three well-observed CMEs that exploded from flare regions of extremely different size and magnetic setting. One of these CMEs was an over-and-out CME, that is, in the outer corona the CME was laterally far offset from the flare-marked source of the driving magnetic explosion. In each event, the estimated source-region field strength is appropriate for the magnetic setting of the flare. This agreement (1) indicates that CMEs are propelled by the magnetic field of the CME plasmoid pushing against the surrounding magnetic field; (2) supports the magnetic-arch-blowout scenario for over-and-out CMEs; and (3) shows that a CME's final angular width in the outer corona can be estimated from the amount of magnetic flux covered by the source-region flare arcade.

Outer Retinal Tubulation in Degenerative Retinal Disorders

PubMed Central

Goldberg, Naomi R.; Greenberg, Jonathan P.; Laud, Ketan; Tsang, Stephen; Freund, K. Bailey

2013-01-01

Objective To demonstrate outer retinal tubulation (ORT) in various degenerative retinal disorders. Methods This was a retrospective review of the multimodal imaging of 29 eyes of 15 patients with various retinal dystrophies and inflammatory maculopathies manifesting ORT. The morphologic features of ORT and its evolution over time were analyzed using spectral-domain optical coherence tomography (SD-OCT) data. Results Outer retinal tubulation was identified as round or ovoid structures with hyper-reflective borders in pattern dystrophy (6 eyes), acute zonal occult outer retinopathy (5 eyes), retinitis pigmentosa (4 eyes), Stargardt disease (4 eyes), gyrate atrophy (2 eyes), choroideremia (2 eyes), and various other degenerative conditions. These structures appeared to develop from the invagination of photoreceptors at the junction of intact and atrophic outer retina. During follow-up, the number and distribution of ORT largely remained stable. As zones of atrophy enlarged, the frequency of ORT appeared to increase. The ORT structures were found in fewer than 10% of patients with retinitis pigmentosa, Stargardt, or pattern dystrophy. Conclusion Outer retinal tubulation is found in various degenerative retinal disorders that share in common damage to the outer retina and/or retinal pigment epithelium. The presence of ORT may be in an indicator of underlying disease stage and severity. PMID:23676993

Large thermal protection system panel

NASA Technical Reports Server (NTRS)

Weinberg, David J. (Inventor); Myers, Franklin K. (Inventor); Tran, Tu T. (Inventor)

2003-01-01

A protective panel for a reusable launch vehicle provides enhanced moisture protection, simplified maintenance, and increased temperature resistance. The protective panel includes an outer ceramic matrix composite (CMC) panel, and an insulative bag assembly coupled to the outer CMC panel for isolating the launch vehicle from elevated temperatures and moisture. A standoff attachment system attaches the outer CMC panel and the bag assembly to the primary structure of the launch vehicle. The insulative bag assembly includes a foil bag having a first opening shrink fitted to the outer CMC panel such that the first opening and the outer CMC panel form a water tight seal at temperatures below a desired temperature threshold. Fibrous insulation is contained within the foil bag for protecting the launch vehicle from elevated temperatures. The insulative bag assembly further includes a back panel coupled to a second opening of the foil bag such that the fibrous insulation is encapsulated by the back panel, the foil bag, and the outer CMC panel. The use of a CMC material for the outer panel in conjunction with the insulative bag assembly eliminates the need for waterproofing processes, and ultimately allows for more efficient reentry profiles.

30 CFR 256.4 - Authority.

Code of Federal Regulations, 2011 CFR

2011-07-01

... OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas... for oil and gas, and sulphur, in submerged lands of the outer Continental Shelf (OCS). The Act... major oil and gas producers. [64 FR 72795, Dec. 28, 1999] ...

Attachment device for an inflatable protective cushion

DOEpatents

Nelsen, J.M.; Luna, D.A.; Gwinn, K.W.

1997-11-18

An inflatable cushion assembly for use with an inflator comprises an inflatable cushion having an inner surface, outer surface, and at least one protrusion extending from one of the inner or outer surfaces. The inflatable cushion defines an opening between the inner surface and the outer surface for receiving the inflator. An attachment member contacts the one of the inner or outer surfaces adjacent the opening and includes a groove for receiving the protrusion, the attachment member securing the inflator within the opening. 22 figs.

Attachment device for an inflatable protective cushion

DOEpatents

Nelsen, J.M.; Luna, D.A.; Gwinn, K.W.

1998-12-08

An inflatable cushion assembly for use with an inflator comprises an inflatable cushion having an inner surface, outer surface, and at least one protrusion extending from one of the inner or outer surfaces. The inflatable cushion defines an opening between the inner surface and the outer surface for receiving the inflator. An attachment member contacts the one of the inner or outer surfaces adjacent the opening and includes a groove for receiving the protrusion, the attachment member securing the inflator within the opening. 22 figs.

Lid design for low level waste container

DOEpatents

Holbrook, R.H.; Keener, W.E.

1995-02-28

A container for low level waste includes a shell and a lid. The lid has a frame to which a planar member is welded. The lid frame includes a rectangular outer portion made of square metal tubing, a longitudinal beam extending between axial ends of the rectangular outer portion, and a transverse beam extending between opposite lateral sides of the rectangular outer portion. Two pairs of diagonal braces extend between the longitudinal beam and the four corners of the rectangular outer portion of the frame. 6 figs.

Liquid metal reactor air cooling baffle

DOEpatents

Hunsbedt, Anstein

1994-01-01

A baffle is provided between a relatively hot containment vessel and a relatively cold silo for enhancing air cooling performance. The baffle includes a perforate inner wall positionable outside the containment vessel to define an inner flow riser therebetween, and an imperforate outer wall positionable outside the inner wall to define an outer flow riser therebetween. Apertures in the inner wall allow thermal radiation to pass laterally therethrough to the outer wall, with cooling air flowing upwardly through the inner and outer risers for removing heat.

Lid design for low level waste container

DOEpatents

Holbrook, Richard H.; Keener, Wendell E.

1995-01-01

A container for low level waste includes a shell and a lid. The lid has a frame to which a planar member is welded. The lid frame includes a rectangular outer portion made of square metal tubing, a longitudinal beam extending between axial ends of the rectangular outer portion, and a transverse beam extending between opposite lateral sides of the rectangular outer portion. Two pairs of diagonal braces extend between the longitudinal beam and the four corners of the rectangular outer portion of the frame.

Method for Detecting Perlite Compaction in Large Cryogenic Tanks

NASA Technical Reports Server (NTRS)

Youngquist, Robert

2010-01-01

Perlite is the most typical insulating powder used to separate the inner and outer shells of cryogenic tanks. The inner tank holds the low-temperature commodity, while the outer shell is exposed to the ambient temperature. Perlite minimizes radiative energy transfer between the two tanks. Being a powder, perlite will settle over time, leading to the danger of transferring any loads from the inner shell to the outer shell. This can cause deformation of the outer shell, leading to damaged internal fittings. The method proposed is to place strain or displacement sensors on several locations of the outer shell. Loads induced on the shell by the expanding inner shell and perlite would be monitored, providing an indication of the location and degree of compaction.

Electrochemical cell design

DOEpatents

Arntzen, John D.

1978-01-01

An electrochemical cell includes two outer electrodes and a central electrode of opposite polarity, all nested within a housing having two symmetrical halves which together form an offset configuration. The outer electrodes are nested within raised portions within the side walls of each housing half while the central electrode sealingly engages the perimetric margins of the side-wall internal surfaces. Suitable interelectrode separators and electrical insulating material electrically isolate the central electrode from the housing and the outer electrodes. The outer electrodes are electrically connected to the internal surfaces of the cell housing to provide current collection. The nested structure minimizes void volume that would otherwise be filled with gas or heavy electrolyte and also provides perimetric edge surfaces for sealing and supporting at the outer margins of frangible interelectrode separator layers.

Independent segregation of two antigenic specificities (VP3 and VP7) involved in neutralization of rotavirus infectivity.

PubMed Central

Hoshino, Y; Sereno, M M; Midthun, K; Flores, J; Kapikian, A Z; Chanock, R M

1985-01-01

Antiserum prepared against the M37 strain of rotavirus, recovered from an asymptomatic newborn infant in Venezuela, neutralized two prototype human rotaviruses that define two separate serotypes: serotype 1 (Wa) and serotype 4 (ST3). Thus, the M37 strain is a naturally occurring intertypic rotavirus. Analysis of reassortant viruses produced during coinfection in vitro indicated that the observed dual serotype specificity of M37 resulted from sharing a related outer capsid protein, VP3, with the ST3 virus and another related outer capsid protein, VP7, with the Wa virus. Analysis of single (VP3)-gene-substitution reassortants indicated that VP3 was as potent an immunogen as VP7. In addition, direct evidence was obtained that the serotype specificity of neutralizing antibody elicited by VP3 can differ from the serotype specificity of neutralizing antibody elicited by VP7, indicating the need for a dual system of rotavirus classification in which the neutralization specificity of both VP3 and VP7 outer capsid proteins are identified. Images PMID:3001716

Suppression of the lethal effect of acidic-phospholipid deficiency by defective formation of the major outer membrane lipoprotein in Escherichia coli.

PubMed Central

Asai, Y; Katayose, Y; Hikita, C; Ohta, A; Shibuya, I

1989-01-01

The Escherichia coli pgsA3 allele encoding a defective phosphatidylglycerophosphate synthase is lethal for all but certain strains. Genetic analysis of such strains has revealed that the lethal effect is fully suppressed by the lack of the major outer membrane lipoprotein that consumes phosphatidylglycerol for its maturation. Images PMID:2556377

A Bibliography of Aerospace Books and Teaching Aids for Secondary School Students and Teachers

DTIC Science & Technology

1961-11-13

p., llus.. HEim-E5. KENNETH. A.N ADVENTURE IN ASTRO.NOMY. 19539. $2.50. An introduction to radio astrono )my Viking. 127 1P.. illus.. 1958. $3.30...8217. ASTRONO )MY. Watts. 2:A; l., illus.. 1960. outer Si1-Pe. 14.5. The history of astronomy, the development Mt-rz,. lai.tyl. Tilns IS OUTER SPACE

Formation of ZrO{sub 2} in coating on Mg–3 wt.%Al–1 wt.%Zn alloy via plasma electrolytic oxidation: Phase and structure of zirconia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Kang Min; Kim, Yeon Sung; Yang, Hae Woong

2015-01-15

An investigation of the coating structure formed on Mg–3 wt.%Al–1 wt.%Zn alloy sample subjected to plasma electrolytic oxidation was examined by field-emission transmission electron microscopy. The plasma electrolytic oxidation process was conducted in a phosphoric acid electrolyte containing K{sub 2}ZrF{sub 6} for 600 s. Microstructural observations showed that the coating consisting of MgO, MgF{sub 2}, and ZrO{sub 2} phases was divided into three distinctive parts, the barrier, intermediate, and outer layers. Nanocrystalline MgO and MgF{sub 2} compounds were observed mainly in the barrier layer of ~ 1 μm thick near to the substrate. From the intermediate to outer layers, variousmore » ZrO{sub 2} polymorphs appeared due to the effects of the plasma arcing temperature on the phase transition of ZrO{sub 2} compounds during the plasma electrolytic oxidation process. In the outer layer, MgO compound grew in the form of a dendrite-like structure surrounded by cubic ZrO{sub 2}. - Highlights: • The barrier layer containing MgO and MgF{sub 2} was observed near to the Mg substrate. • In the intermediate layer, m-, t-, and o-ZrO{sub 2} compounds were additionally detected. • The outer layer contained MgO with the dendrite-like structure surrounded by c-ZrO{sub 2}. • The grain sizes of compounds in oxide layer increased from barrier to outer layer.« less

Oxygen isotope reservoirs in the outer asteroid belt inferred from oxygen isotope systematics of chondrule olivines and isolated forsterite and olivine grains in Tagish Lake-type carbonaceous chondrites, WIS 91600 and MET 00432

NASA Astrophysics Data System (ADS)

Yamanobe, Masakuni; Nakamura, Tomoki; Nakashima, Daisuke

2018-03-01

To understand oxygen isotope ratios and redox conditions of the chondrule formation environments of the outer rigions of the asteroid belt, we analyzed major element concentrations and oxygen isotope ratios of olivine grains in chondrules, isolated forsterite, and isolated olivine from the WIS 91600 and MET 00432 carbonaceous chondrites, which are thought to have originated from D-type asteroids located in the outer asteroid belt. The oxygen isotope ratios of individual chondrules and isolated grains show a wide variation in δ18O from -9.9‰ to +9.1‰ along the carbonaceous chondrite anhydrous mineral (CCAM) and primitive chondrule mineral (PCM) lines. The Δ17O (= δ17O - 0.52 × δ18O) values of the measured objects increase with decreasing Mg#; i.e., FeO-poor objects (Mg# > 90; type I chondrules and isolated forsterites) mainly have Δ17O values of ca. -6‰, and FeO-rich objects (Mg# < 90; type II chondrules and isolated olivines) have Δ17O values ranging from -3‰ to +2‰. Similar trends are observed for ferromagnesian silicate particles from comet Wild2 and CR chondrite chondrules, particularly in terms of FeO-rich objects with Δ17O values ranging from -3‰ to +2‰. It is suggested that FeO-rich objects formed in the outer regions of the asteroid belt and were transported to the outer solar nebular regions where comet Wild2 formed.

Facilitative glucose transporter Glut1 is actively excluded from rod outer segments.

PubMed

Gospe, Sidney M; Baker, Sheila A; Arshavsky, Vadim Y

2010-11-01

Photoreceptors are among the most metabolically active cells in the body, relying on both oxidative phosphorylation and glycolysis to satisfy their high energy needs. Local glycolysis is thought to be particularly crucial in supporting the function of the photoreceptor's light-sensitive outer segment compartment, which is devoid of mitochondria. Accordingly, it has been commonly accepted that the facilitative glucose transporter Glut1 responsible for glucose entry into photoreceptors is localized in part to the outer segment plasma membrane. However, we now demonstrate that Glut1 is entirely absent from the rod outer segment and is actively excluded from this compartment by targeting information present in its cytosolic C-terminal tail. Our data indicate that glucose metabolized in the outer segment must first enter through other parts of the photoreceptor cell. Consequently, the entire energy supply of the outer segment is dependent on diffusion of energy-rich substrates through the thin connecting cilium that links this compartment to the rest of the cell.

Process for the manufacture of seamless metal-clad fiber-reinforced organic matrix composite structures

NASA Technical Reports Server (NTRS)

Bluck, Raymond M. (Inventor); Bush, Harold G. (Inventor); Johnson, Robert R. (Inventor)

1991-01-01

A process for producing seamless metal-clad composite structures includes providing a hollow, metallic inner member and an outer sleeve to surround the inner member and define an inner space therebetween. A plurality of continuous reinforcing fibers is attached to the distal end of the outside diameter of the inner member, and the inner member is then introduced, distal end first, into one end of the outer sleeve. The inner member is then moved, distal end first, into the outer sleeve until the inner member is completely enveloped by the outer sleeve. A liquid matrix material is then injected into the space containing the reinforcing fibers between the inner member and the outer sleeve. Next a pressurized heat transfer medium is passed through the inner member to cure the liquid matrix material. Finally, the wall thickness of both the inner member and the outer sleeve are reduced to desired dimensions by chemical etching, which adjusts the thermal expansion coefficient of the metal-clad composite structure to a desired value.

[Stress analysis on the acetabular side of bipolar hemiarthroplasty by the two-dimensional finite element method incorporating the boundary friction layer].

PubMed

Ichihashi, K; Imura, S; Oomori, H; Gesso, H

1994-11-01

We compared the biomechanical characteristics of bipolar and unipolar hemiarthroplasty on the proximal migration of the outer head by determining the von Mises stress distribution and acetabular (outer head) displacement with clinical assessment of hemiarthroplasty in 75 patients. This analysis used the two-dimensional finite element method, which incorporated boundary friction layers on both the inner and outer bearings of the prosthesis. Acetabular reaming increased stress within the pelvic bone and migration of the outer head. A combination of the acetabular reaming and bone transplantation increased the stress within the pelvic bone and grafted bone, and caused outer head migration. These findings were supported by clinical results. Although the bipolar endoprosthesis was biomechanically superior to the unipolar endoprosthesis, migration of the outer head still occurred. The bipolar endoprosthesis appeared to be indicated in cases of a femoral neck fracture or of avascular necrosis in the femoral head, but its use in cases of osteoarthritis in the hip required caution.

A nonlinear cochlear model with the outer hair cell piezoelectric activity

NASA Astrophysics Data System (ADS)

Jiang, Xiaoai; Grosh, Karl

2003-10-01

In this paper we present a simple cochlear model which captures the most important aspect of nonlinearity in the cochlea-the nonlinearity caused by the piezoelectric-like activity of outer hair cells and the variable conductance of the outer hair cell stereocilia. A one-dimensional long-wave model is built to simulate the dynamic response of the fluid-loaded basilar membrane. The basilar membrane is simulated as isolated linear oscillators along the cochlear length, and its motion is coupled with the fluid pressure and the nonlinear force produced by the outer hair cells. As the basilar membrane moves, the fluid shears stereocilia, and the resulting ion flow changes the transmembrane potential of the outer hair cells and subsequently their length, leading to further movement of the basilar membrane. The piezoelectric-like activity of the outer hair cell is simulated by a current source, and stereocilia motion is modeled as a varying conductance that changes as the basilar membrane moves. A solution in the time domain will be presented. [Work supported by NIH.

Four-wall turbine airfoil with thermal strain control for reduced cycle fatigue

DOEpatents

Cambell, Christian X

2013-09-17

A turbine airfoil (20B) with a thermal expansion control mechanism that increases the airfoil camber (60, 61) under operational heating. The airfoil has four-wall geometry, including pressure side outer and inner walls (26, 28B), and suction side outer and inner walls (32, 34B). It has near-wall cooling channels (31F, 31A, 33F, 33A) between the outer and inner walls. A cooling fluid flow pattern (50C, 50W, 50H) in the airfoil causes the pressure side inner wall (28B) to increase in curvature under operational heating. The pressure side inner wall (28B) is thicker than walls (26, 34B) that oppose it in camber deformation, so it dominates them in collaboration with the suction side outer wall (32), and the airfoil camber increases. This reduces and relocates a maximum stress area (47) from the suction side outer wall (32) to the suction side inner wall (34B, 72) and the pressure side outer wall (26).

Electrophoretic characterisation of the outer membrane proteins of Yersinia pestis isolated in north-east Brazil.

PubMed Central

Abath, F. G.; Almeida, A. M.; Ferreira, L. C.

1989-01-01

The outer membrane proteins of 38 Yersinia pestis isolates from all known plague foci of north-east Brazil were analysed by SDS-PAGE. Approximately 20 bands were consistently found in all strains analysed and 11 were selected for comparative studies. Although qualitative differences among the electrophoretic profiles of outer membrane proteins of wild Y. pestis isolates were not observed, quantitative alterations were clearly noted for most of these proteins. No particular quantitative alteration of the electrophoretic profile of outer membrane proteins could be associated with the period of isolation and geographic origin of the isolates. The 64 kDa outer membrane protein was significantly expressed in higher amounts among Y. pestis strains isolated from a recent plague outbreak. The possible use of electrophoretic profiles of outer membrane proteins of wild Y. pestis isolates as a tool for epidemiological studies and for the analysis of virulence determinants is discussed. Images Fig. 2 PMID:2606164

Mechanical thermal motor

NASA Technical Reports Server (NTRS)

Hein, L. A.; Myers, W. N. (Inventor)

1976-01-01

An apparatus is described for converting thermal energy such as solar energy into mechanical motion for driving fluid pumps and similar equipment. The thermal motor comprises an inner concentric cylinder carried by a stationary core member. The core member has a cylindrical disc plate fixed adjacent to a lower portion and extending radially from it. An outer concentric cylinder rotatably carried on the disc plate defining a space between the inner and outer concentric cylinders. A spiral tubular member encircles the inner concentric cylinder and is contained within the space between the inner and outer cylinders. One portion is connected to the inner concentric cylinder and a second portion connected to the outer concentric cylinder. A heated fluid is conveyed through the tubular member and is periodically cooled causing the tubular member to expand and contract. This causes the outer concentric cylinder to reciprocally rotate on the base plate accordingly. The reciprocating motion of the outer concentric cylinder is then utilized to drive a pump member in a pump chamber.

First-principles calculation of the geometric and electronic structure of the Be(0001) surface

NASA Astrophysics Data System (ADS)

Feibelman, Peter J.

1992-07-01

Linearized-augmented-plane-wave calculations for a nine-layer Be(0001) slab agree with the unusual experimental finding of a substantial outer-layer expansion relative to the truncated bulk lattice. They imply that the separation between the outer two layers should be 3.9% larger than in the bulk, while the second- to third-layer separation should be 2.2% larger. The surface expansion is accompanied by demotion of pσ to s electrons on outer-layer Be's. The surface Be's loss of three neighbors makes the energy cost of s- to pσ-electron promotion, which is necessary for the formation of strong bonds to the next layer down, less profitable than in the bulk.

Purification and Bicelle Crystallization for Structure Determination of the E. coli Outer Membrane Protein TamA.

PubMed

Gruss, Fabian; Hiller, Sebastian; Maier, Timm

2015-01-01

TamA is an Omp85 protein involved in autotransporter assembly in the outer membrane of Escherichia coli. It comprises a C-terminal 16-stranded transmembrane β-barrel as well as three periplasmic POTRA domains, and is a challenging target for structure determination. Here, we present a method for crystal structure determination of TamA, including recombinant expression in E. coli, detergent extraction, chromatographic purification, and bicelle crystallization in combination with seeding. As a result, crystals in space group P21212 are obtained, which diffract to 2.3 Å resolution. This protocol also serves as a template for structure determination of other outer membrane proteins, in particular of the Omp85 family.

Evolution of Initial Atmospheric Corrosion of Carbon Steel in an Industrial Atmosphere

NASA Astrophysics Data System (ADS)

Pan, Chen; Han, Wei; Wang, Zhenyao; Wang, Chuan; Yu, Guocai

2016-12-01

The evolution of initial corrosion of carbon steel exposed to an industrial atmosphere in Shenyang, China, has been investigated by gravimetric, XRD, SEM/EDS and electrochemical techniques. The kinetics of the corrosion process including the acceleration and deceleration processes followed the empirical equation D = At n . The rust formed on the steel surface was bi-layered, comprised of an inner and outer layer. The outer layer was formed within the first 245 days and had lower iron content compared to the inner layer. However, the outer layer disappeared after 307 days of exposure, which is considered to be associated with the depletion of Fe3O4. The evolution of the rust layer formed on the carbon steel has also been discussed.

Multiple Lines of Evidence Localize Signaling, Morphology, and Lipid Biosynthesis Machinery to the Mitochondrial Outer Membrane of Arabidopsis[W][OA

PubMed Central

Duncan, Owen; Taylor, Nicolas L.; Carrie, Chris; Eubel, Holger; Kubiszewski-Jakubiak, Szymon; Zhang, Botao; Narsai, Reena; Millar, A. Harvey; Whelan, James

2011-01-01

The composition of the mitochondrial outer membrane is notoriously difficult to deduce by orthology to other organisms, and biochemical enrichments are inevitably contaminated with the closely associated inner mitochondrial membrane and endoplasmic reticulum. In order to identify novel proteins of the outer mitochondrial membrane in Arabidopsis (Arabidopsis thaliana), we integrated a quantitative mass spectrometry analysis of highly enriched and prefractionated samples with a number of confirmatory biochemical and cell biology approaches. This approach identified 42 proteins, 27 of which were novel, more than doubling the number of confirmed outer membrane proteins in plant mitochondria and suggesting novel functions for the plant outer mitochondrial membrane. The novel components identified included proteins that affected mitochondrial morphology and/or segregation, a protein that suggests the presence of bacterial type lipid A in the outer membrane, highly stress-inducible proteins, as well as proteins necessary for embryo development and several of unknown function. Additionally, proteins previously inferred via orthology to be present in other compartments, such as an NADH:cytochrome B5 reductase required for hydroxyl fatty acid accumulation in developing seeds, were shown to be located in the outer membrane. These results also revealed novel proteins, which may have evolved to fulfill plant-specific requirements of the mitochondrial outer membrane, and provide a basis for the future functional characterization of these proteins in the context of mitochondrial intracellular interaction. PMID:21896887

Planar ceramic membrane assembly and oxidation reactor system

DOEpatents

Carolan, Michael Francis; Dyer, legal representative, Kathryn Beverly; Wilson, Merrill Anderson; Ohm, Ted R.; Kneidel, Kurt E.; Peterson, David; Chen, Christopher M.; Rackers, Keith Gerard; Dyer, deceased, Paul Nigel

2007-10-09

Planar ceramic membrane assembly comprising a dense layer of mixed-conducting multi-component metal oxide material, wherein the dense layer has a first side and a second side, a porous layer of mixed-conducting multi-component metal oxide material in contact with the first side of the dense layer, and a ceramic channeled support layer in contact with the second side of the dense layer. The planar ceramic membrane assembly can be used in a ceramic wafer assembly comprising a planar ceramic channeled support layer having a first side and a second side; a first dense layer of mixed-conducting multi-component metal oxide material having an inner side and an outer side, wherein the inner side is in contact with the first side of the ceramic channeled support layer; a first outer support layer comprising porous mixed-conducting multi-component metal oxide material and having an inner side and an outer side, wherein the inner side is in contact with the outer side of the first dense layer; a second dense layer of mixed-conducting multi-component metal oxide material having an inner side and an outer side, wherein the inner side is in contact with the second side of the ceramic channeled layer; and a second outer support layer comprising porous mixed-conducting multi-component metal oxide material and having an inner side and an outer side, wherein the inner side is in contact with the outer side of the second dense layer.

Planar ceramic membrane assembly and oxidation reactor system

DOEpatents

Carolan, Michael Francis; Dyer, legal representative, Kathryn Beverly; Wilson, Merrill Anderson; Ohrn, Ted R.; Kneidel, Kurt E.; Peterson, David; Chen, Christopher M.; Rackers, Keith Gerard; Dyer, Paul Nigel

2009-04-07

Planar ceramic membrane assembly comprising a dense layer of mixed-conducting multi-component metal oxide material, wherein the dense layer has a first side and a second side, a porous layer of mixed-conducting multi-component metal oxide material in contact with the first side of the dense layer, and a ceramic channeled support layer in contact with the second side of the dense layer. The planar ceramic membrane assembly can be used in a ceramic wafer assembly comprising a planar ceramic channeled support layer having a first side and a second side; a first dense layer of mixed-conducting multi-component metal oxide material having an inner side and an outer side, wherein the inner side is in contact with the first side of the ceramic channeled support layer; a first outer support layer comprising porous mixed-conducting multi-component metal oxide material and having an inner side and an outer side, wherein the inner side is in contact with the outer side of the first dense layer; a second dense layer of mixed-conducting multi-component metal oxide material having an inner side and an outer side, wherein the inner side is in contact with the second side of the ceramic channeled layer; and a second outer support layer comprising porous mixed-conducting multi-component metal oxide material and having an inner side and an outer side, wherein the inner side is in contact with the outer side of the second dense layer.

Prompt enhancement of the Earth's outer radiation belt due to substorm electron injections

DOE PAGES

Tang, C. L.; Zhang, J. -C.; Reeves, G. D.; ...

2016-12-17

Here, we present multipoint simultaneous observations of the near-Earth magnetotail and outer radiation belt during the substorm electron injection event on 16 August 2013. Time History of Events and Macroscale Interactions during Substorms A in the near-Earth magnetotail observed flux-enhanced electrons of 300 keV during the magnetic field dipolarization. Geosynchronous orbit satellites also observed the intensive electron injections. Located in the outer radiation belt, RBSP-A observed enhancements of MeV electrons accompanied by substorm dipolarization. The phase space density (PSD) of MeV electrons at L* ~5.4 increased by 1 order of magnitude in 1 h, resulting in a local PSD peakmore » of MeV electrons, which was caused by the direct effect of substorm injections. We also detected an enhanced MeV electrons in the heart of the outer radiation belt within 2 h, which may be associated with intensive substorm electron injections and subsequent local acceleration by chorus waves. Multipoint observations have shown that substorm electron injections not only can be the external source of MeV electrons at the outer edge of the outer radiation belt (L* ~5.4) but also can provide the intensive seed populations in the outer radiation belt. These initial higher-energy electrons from injection can reach relativistic energy much faster. Furthermore, these observations also provide evidence that enhanced substorm electron injections can explain rapid enhancements of MeV electrons in the outer radiation belt.« less

Prompt enhancement of the Earth's outer radiation belt due to substorm electron injections

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tang, C. L.; Zhang, J. -C.; Reeves, G. D.

Here, we present multipoint simultaneous observations of the near-Earth magnetotail and outer radiation belt during the substorm electron injection event on 16 August 2013. Time History of Events and Macroscale Interactions during Substorms A in the near-Earth magnetotail observed flux-enhanced electrons of 300 keV during the magnetic field dipolarization. Geosynchronous orbit satellites also observed the intensive electron injections. Located in the outer radiation belt, RBSP-A observed enhancements of MeV electrons accompanied by substorm dipolarization. The phase space density (PSD) of MeV electrons at L* ~5.4 increased by 1 order of magnitude in 1 h, resulting in a local PSD peakmore » of MeV electrons, which was caused by the direct effect of substorm injections. We also detected an enhanced MeV electrons in the heart of the outer radiation belt within 2 h, which may be associated with intensive substorm electron injections and subsequent local acceleration by chorus waves. Multipoint observations have shown that substorm electron injections not only can be the external source of MeV electrons at the outer edge of the outer radiation belt (L* ~5.4) but also can provide the intensive seed populations in the outer radiation belt. These initial higher-energy electrons from injection can reach relativistic energy much faster. Furthermore, these observations also provide evidence that enhanced substorm electron injections can explain rapid enhancements of MeV electrons in the outer radiation belt.« less

Hydroxyl Ion Diffusion through Radicular Dentine When Calcium Hydroxide Is Used under Different Conditions

PubMed Central

Cai, Michael; Castro Salgado, Jacqueline

2018-01-01

Calcium hydroxide’s anti-bacterial action relies on high pH. The aim here was to investigate hydroxyl ion diffusion through dentine under different conditions. Teeth were divided into control (n = 4) and four experimental groups (n = 10): Group 1—no medicament; Group 2—Calmix; Group 3—Calmix/Ledermix; Group 4—Calasept Plus/Ledermix; Group 5—Pulpdent/smear layer. Deep (inner dentine) and shallow (outer dentine) cavities were cut into each root. pH was measured in these cavities for 12 weeks. The inner and outer dentine pH in Group 2 was significantly higher than all groups. Inner dentine pH in Group 3 was slightly higher than that in Group 4 initially but subsequently comparable. After Day 2, Group 5 had significantly lower pH than Groups 3 and 4. The outer dentine pH in Group 3 started higher than that in Groups 4 and 5, but by Day 28 the difference was insignificant. The time for the inner dentine to reach maximum pH was one week for Group 2 and four weeks for Groups 3 and 4. The time for the outer dentine to reach maximum pH was eight weeks for all experimental groups. Mixing different Ca(OH)2 formulations with Ledermix gave similar hydroxyl ion release but pH and total diffusion was lower than Ca(OH)2 alone. The smear layer inhibited diffusion. PMID:29342093

The Outer Limits: English.

ERIC Educational Resources Information Center

Tyler, Barbara R.; Biesekerski, Joan

The Quinmester course "The Outer Limits" involves an exploration of unknown worlds, mental and physical, through fiction and nonfiction. Its purpose is to focus attention on the ongoing conquest of the frontiers of the mind, the physical world, and outer space. The subject matter includes identification and investigation of unknown…

Electron beam selectively seals porous metal filters

NASA Technical Reports Server (NTRS)

Snyder, J. A.; Tulisiak, G.

1968-01-01

Electron beam welding selectively seals the outer surfaces of porous metal filters and impedances used in fluid flow systems. The outer surface can be sealed by melting a thin outer layer of the porous material with an electron beam so that the melted material fills all surface pores.

A Digital Temperature Control and Measurement System.

DTIC Science & Technology

1980-07-04

tubing. Vacuum connections, indicated by closed circles, are made with elastomer o-rings. 9.10 The outer vacuum can A is made entirely of aluminum , which...provides good thermal conductivity with minimal weight. Around the outer can is wrapped a 3/8" o.d. aluminum 3 tubing at one turn per inch. The first...through the aluminum tubing. The second stage, radiation shield B. is made entirely of coDper. A heater wire of #32 manganin wire with a total

The role of outer membrane in Serratia marcescens intrinsic resistance to antibiotics.

PubMed

Sánchez, L; Ruiz, N; Leranoz, S; Viñas, M; Puig, M

1997-09-01

Three different porins from Serratia marcescens were described. They were named Omp1, Omp2 and Omp3 and their molecular weights were 42, 40 and 39 kDa respectively. Omp2 and Omp3 showed osmoregulation and thermoregulation in a similar way to OmpC and OmpF of Escherichia coli. Permeability coefficients of the outer membrane of this species were calculated following the Zimmermann and Rosselet method. P values were similar to those obtained in Escherichia coli, which suggests that the chromosomal beta-lactamase would play a major role in the resistance of Serratia marcescens to beta-lactam antibiotics. Both MIC values and permeabilities were modified by salycilates and acetylsalycilate. Synergism between the outer membrane and the beta-lactamase was also evaluated. When bacteria grew in the presence of a beta-lactam in the medium, the beta-lactamase accounted for most of the resistance.

The composition and origin of the C, P, and D asteroids - Water as a tracer of thermal evolution in the outer belt

NASA Technical Reports Server (NTRS)

Jones, Thomas D.; Lebofsky, Larry A.; Lewis, John S.; Marley, Mark S.

1990-01-01

A telescopic and laboratory investigation of water distribution among low albedo asteroids in the outer belt, using the 3-micron reflectance absorption of molecular H2O and structural OH ions (coincident with the 3-micron spectral signature of meteorite and asteroid hydrated silicates) shows that 66 percent of the C-class asteroids in the sample have hydrated silicate surfaces. In conjunction with the apparently anhydrous P and D surfaces, this pronounced hydration difference between C-class asteroids and the more distant P and D classes points to an original outer belt asteroid composition of anhydrous silicates, water ice, and complex organic material. Early solar-wind induction heating of protoasteroids, declining in intensity with distance from the sun, is conjectured to have produced the observed diminution of hydrated silicate abundance.

Outer brain barriers in rat and human development

PubMed Central

Brøchner, Christian B.; Holst, Camilla B.; Møllgård, Kjeld

2015-01-01

Complex barriers at the brain's surface, particularly in development, are poorly defined. In the adult, arachnoid blood-cerebrospinal fluid (CSF) barrier separates the fenestrated dural vessels from the CSF by means of a cell layer joined by tight junctions. Outer CSF-brain barrier provides diffusion restriction between brain and subarachnoid CSF through an initial radial glial end feet layer covered with a pial surface layer. To further characterize these interfaces we examined embryonic rat brains from E10 to P0 and forebrains from human embryos and fetuses (6–21st weeks post-conception) and adults using immunohistochemistry and confocal microscopy. Antibodies against claudin-11, BLBP, collagen 1, SSEA-4, MAP2, YKL-40, and its receptor IL-13Rα2 and EAAT1 were used to describe morphological characteristics and functional aspects of the outer brain barriers. Claudin-11 was a reliable marker of the arachnoid blood-CSF barrier. Collagen 1 delineated the subarachnoid space and stained pial surface layer. BLBP defined radial glial end feet layer and SSEA-4 and YKL-40 were present in both leptomeningeal cells and end feet layer, which transformed into glial limitans. IL-13Rα2 and EAAT1 were present in the end feet layer illustrating transporter/receptor presence in the outer CSF-brain barrier. MAP2 immunostaining in adult brain outlined the lower border of glia limitans; remnants of end feet were YKL-40 positive in some areas. We propose that outer brain barriers are composed of at least 3 interfaces: blood-CSF barrier across arachnoid barrier cell layer, blood-CSF barrier across pial microvessels, and outer CSF-brain barrier comprising glial end feet layer/pial surface layer. PMID:25852456

Outer brain barriers in rat and human development.

PubMed

Brøchner, Christian B; Holst, Camilla B; Møllgård, Kjeld

2015-01-01

Complex barriers at the brain's surface, particularly in development, are poorly defined. In the adult, arachnoid blood-cerebrospinal fluid (CSF) barrier separates the fenestrated dural vessels from the CSF by means of a cell layer joined by tight junctions. Outer CSF-brain barrier provides diffusion restriction between brain and subarachnoid CSF through an initial radial glial end feet layer covered with a pial surface layer. To further characterize these interfaces we examined embryonic rat brains from E10 to P0 and forebrains from human embryos and fetuses (6-21st weeks post-conception) and adults using immunohistochemistry and confocal microscopy. Antibodies against claudin-11, BLBP, collagen 1, SSEA-4, MAP2, YKL-40, and its receptor IL-13Rα2 and EAAT1 were used to describe morphological characteristics and functional aspects of the outer brain barriers. Claudin-11 was a reliable marker of the arachnoid blood-CSF barrier. Collagen 1 delineated the subarachnoid space and stained pial surface layer. BLBP defined radial glial end feet layer and SSEA-4 and YKL-40 were present in both leptomeningeal cells and end feet layer, which transformed into glial limitans. IL-13Rα2 and EAAT1 were present in the end feet layer illustrating transporter/receptor presence in the outer CSF-brain barrier. MAP2 immunostaining in adult brain outlined the lower border of glia limitans; remnants of end feet were YKL-40 positive in some areas. We propose that outer brain barriers are composed of at least 3 interfaces: blood-CSF barrier across arachnoid barrier cell layer, blood-CSF barrier across pial microvessels, and outer CSF-brain barrier comprising glial end feet layer/pial surface layer.

Effect of ranibizumab on high-speed indocyanine green angiography and minimum intensity projection optical coherence tomography findings in neovascular age-related macular degeneration.

PubMed

Nicholson, Benjamin P; Nigam, Divya; Toy, Brian; Stetson, Paul F; Agrón, Elvira; Jacobs-El, Naima; Cunningham, Denise; Cukras, Catherine; Wong, Wai; Wiley, Henry; Chew, Emily; Ferris, Frederick; Meyerle, Catherine B

2015-01-01

The purpose of this 1-year prospective study was to investigate how induction/pro re nata ranibizumab intravitreal treatment of eyes with neovascular age-related macular degeneration affects the anatomy of choroidal neovascularization (CNV) and the overlying outer retinal tissue. High-speed indocyanine green (HS-ICG) angiography measurements provided quantification of the CNV size in 60 patients followed for 1 year. Minimum intensity projection optical coherence tomography (MinIP OCT), a novel algorithm assessing minimum optical intensity between the internal limiting membrane and retinal pigment epithelium, measured the area of outer retinal disruption overlying the CNV. Fluorescein angiography was also assessed to evaluate late retinal leakage. After 1 year, the mean area of CNV measured with indocyanine green angiography decreased by 5.8%. The mean area of MinIP OCT of outer retinal disruption overlying the CNV decreased by 4.2%. Mean area of fluorescein angiography leakage decreased by 6.3%. Both the area of outer retinal disruption measured with MinIP OCT and the area of leakage on fluorescein angiography typically exceeded the area of CNV on indocyanine green angiography at baseline and 1 year. Choroidal neovascularization treated with induction/pro re nata intravitreal ranibizumab for 1 year essentially remained static. Minimum intensity projection optical coherence tomography suggests that the area of outer retinal disruption overlying the CNV may be greater than the CNV itself and often correlates with the leakage area on fluorescein angiography. Additionally, there was minimal change in the area of outer retinal disruption on MinIP OCT even when fluid resolved. Measurements of the extent of CNV lesions based on indocyanine green angiography and MinIP OCT may provide useful outcome variables to help assess the CNV complex longitudinally and warrant further validation.

Measuring In Vivo Free Radical Production by the Outer Retina

PubMed Central

Berkowitz, Bruce A.; Bredell, Bryce X.; Davis, Christopher; Samardzija, Marijana; Grimm, Christian; Roberts, Robin

2015-01-01

Purpose Excessive and continuously produced free radicals in the outer retina are implicated in retinal aging and the pathogenesis of sight-threatening retinopathies, yet measuring outer retinal oxidative stress in vivo remains a challenge. Here, we test the hypothesis that continuously produced paramagnetic free radicals from the outer retina can be measured in vivo using high-resolution (22-μm axial resolution) 1/T1magnetic resonance imaging (MRI) without and with a confirmatory quench (quench-assisted MRI). Methods Low-dose sodium iodate–treated and diabetic C57Bl6/J mice (and their controls), and rod-dominated (129S6) or cone-only R91W;Nrl−/− mice were studied. In dark-adapted groups, 1/T1 was mapped transretinally in vivo without or with (1) the antioxidant combination of methylene blue (MB) and α-lipoic acid (LPA), or (2) light exposure; in subgroups, retinal superoxide production was measured ex vivo (lucigenin). Results In the sodium iodate model, retinal superoxide production and outer retina-specific 1/T1 values were both significantly greater than normal and corrected to baseline with MB+LPA therapy. Nondiabetic mice at two ages and 1.2-month diabetic mice (before the appearance of oxidative stress) had similar transretinal 1/T1 profiles. By 2.3 months of diabetes, only outer retinal 1/T1 values were significantly greater than normal and were corrected to baseline with MB+LPA therapy. In mice with healthy photoreceptors, a light quench caused 1/T1 of rods, but not cones, to significantly decrease from their values in the dark. Conclusions Quench-assisted MRI is a feasible method for noninvasively measuring normal and pathologic production of free radicals in photoreceptors/RPE in vivo. PMID:26670830

A MegaCam Survey of Outer Halo Satellites. III. Photometric and Structural Parameters

NASA Astrophysics Data System (ADS)

Muñoz, Ricardo R.; Côté, Patrick; Santana, Felipe A.; Geha, Marla; Simon, Joshua D.; Oyarzún, Grecco A.; Stetson, Peter B.; Djorgovski, S. G.

2018-06-01

We present structural parameters from a wide-field homogeneous imaging survey of Milky Way satellites carried out with the MegaCam imagers on the 3.6 m Canada–France–Hawaii Telescope and 6.5 m Magellan-Clay telescope. Our survey targets an unbiased sample of “outer halo” satellites (i.e., substructures having galactocentric distances greater than 25 kpc) and includes classical dSph galaxies, ultra-faint dwarfs, and remote globular clusters. We combine deep, panoramic gr imaging for 44 satellites and archival gr imaging for 14 additional objects (primarily obtained with the DECam instrument as part of the Dark Energy Survey) to measure photometric and structural parameters for 58 outer halo satellites. This is the largest and most uniform analysis of Milky Way satellites undertaken to date and represents roughly three-quarters (58/81 ≃ 72%) of all known outer halo satellites. We use a maximum-likelihood method to fit four density laws to each object in our survey: exponential, Plummer, King, and Sérsic models. We systematically examine the isodensity contour maps and color–magnitude diagrams for each of our program objects, present a comparison with previous results, and tabulate our best-fit photometric and structural parameters, including ellipticities, position angles, effective radii, Sérsic indices, absolute magnitudes, and surface brightness measurements. We investigate the distribution of outer halo satellites in the size–magnitude diagram and show that the current sample of outer halo substructures spans a wide range in effective radius, luminosity, and surface brightness, with little evidence for a clean separation into star cluster and galaxy populations at the faintest luminosities and surface brightnesses.

The Width of a CME and the Source of the Driving Magnetic Explosion

NASA Technical Reports Server (NTRS)

Moore, R. L.; Sterling, A. C.; Suess, S. T.

2007-01-01

We show that the strength of the magnetic field in the area covered by the flare arcade following a CME-producing ejective solar eruption can be estimated from the final angular width of the CME in the outer corona and the final angular width of the flare arcade. We assume (1) the flux-rope plasmoid ejected from the flare site becomes the interior of the CME plasmoid, (2) in the outer corona the CME is roughly a "spherical plasmoid with legs" shaped like a light bulb, and (3) beyond some height in or below the outer corona the CME plasmoid is in lateral pressure balance with the surrounding magnetic field. The strength of the nearly radial magnetic field in the outer corona is estimated from the radial component of the interplanetary magnetic field measured by Ulysses. We apply this model to three well-observed CMEs that exploded from flare regions of extremely different size and magnetic setting. In each event, the estimated source-region field strength is appropriate for the magnetic setting of the flare. This agreement indicates via the model that CMEs (1) are propelled by the magnetic field of the CME plasmoid pushing against the surrounding magnetic field, and (2) can explode from flare regions that are laterally far offset from the radial path of the CME in the outer corona.

A description of the "event manager" role in resuscitations: A qualitative study of interviews and focus groups of resuscitation participants.

PubMed

Taylor, Katherine L; Parshuram, Christopher S; Ferri, Susan; Mema, Briseida

2017-06-01

Communication during resuscitation is essential for the provision of coordinated, effective care. Previously, we observed 44% of resuscitation communication originated from participants other than the physician team leader; 65% of which was directed to the team, exclusive of the team leader. We called this outer-loop communication. This institutional review board-approved qualitative study used grounded theory analysis of focus groups and interviews to describe and define outer-loop communication and the role of "event manager" as an additional "leader." Participants were health care staff involved in the medical management of resuscitations in a quaternary pediatric academic hospital. The following 3 domains were identified: the existence and rationale of outer-loop communication; the functions fulfilled by outer-loop communication; and the leadership and learning of event manager skills. The role was recognized by all team members and evolved organically as resuscitation complexity increased. A "good" manager has similar qualities to a "good team leader" with strong nontechnical skills. Event managers were not formally identified and no specific training had occurred. "Outer-loop" communication supports resuscitation activities. An event manager gives direction to the team, coordinates activities, and supports the team leader. We describe a new role in resuscitation in light of structural organizational theory and cognitive load with a view to incorporating this structure into resuscitation training. Copyright © 2017 Elsevier Inc. All rights reserved.

Three Members of the LC8/DYNLL Family Are Required for Outer Arm Dynein Motor Function

PubMed Central

Tanner, Christopher A.; Rompolas, Panteleimon; Patel-King, Ramila S.; Gorbatyuk, Oksana; Wakabayashi, Ken-ichi; Pazour, Gregory J.

2008-01-01

The highly conserved LC8/DYNLL family proteins were originally identified in axonemal dyneins and subsequently found to function in multiple enzyme systems. Genomic analysis uncovered a third member (LC10) of this protein class in Chlamydomonas. The LC10 protein is extracted from flagellar axonemes with 0.6 M NaCl and cofractionates with the outer dynein arm in sucrose density gradients. Furthermore, LC10 is specifically missing only from axonemes of those strains that fail to assemble outer dynein arms. Previously, the oda12-1 insertional allele was shown to lack the Tctex2-related dynein light chain LC2. The LC10 gene is located ∼2 kb from that of LC2 and is also completely missing from this mutant but not from oda12-2, which lacks only the 3′ end of the LC2 gene. Although oda12-1 cells assemble outer arms that lack only LC2 and LC10, this strain exhibits a flagellar beat frequency that is consistently less than that observed for strains that fail to assemble the entire outer arm and docking complex (e.g., oda1). These results support a key regulatory role for the intermediate chain/light chain complex that is an integral and highly conserved feature of all oligomeric dynein motors. PMID:18579685

Region-Specific Effect of the Decellularized Meniscus Extracellular Matrix on Mesenchymal Stem Cell-Based Meniscus Tissue Engineering.

PubMed

Shimomura, Kazunori; Rothrauff, Benjamin B; Tuan, Rocky S

2017-03-01

The meniscus is the most commonly injured knee structure, and surgical repair is often ineffective. Tissue engineering-based repair or regeneration may provide a needed solution. Decellularized, tissue-derived extracellular matrices (ECMs) have received attention for their potential use as tissue-engineered scaffolds. In considering meniscus-derived ECMs (mECMs) for meniscus tissue engineering, it is noteworthy that the inner and outer regions of the meniscus have different structural and biochemical features, potentially directing the differentiation of cells toward region-specific phenotypes. To investigate the applicability of mECMs for meniscus tissue engineering by specifically comparing region-dependent effects of mECMs on 3-dimensional constructs seeded with human bone marrow mesenchymal stem cells (hBMSCs). Controlled laboratory study. Bovine menisci were divided into inner and outer halves and were minced, treated with Triton X-100 and DNase, and extracted with urea. Then, hBMSCs (1 × 10 6 cells/mL) were encapsulated in a photo-cross-linked 10% polyethylene glycol diacrylate scaffold containing mECMs (60 μg/mL) derived from either the inner or outer meniscus, with an ECM-free scaffold as a control. The cell-seeded constructs were cultured with chondrogenic medium containing recombinant human transforming growth factor β3 (TGF-β3) and were analyzed for expression of meniscus-associated genes as well as for the collagen (hydroxyproline) and glycosaminoglycan content as a function of time. Decellularization was verified by the absence of 4',6-diamidino-2-phenylindole (DAPI)-stained cell nuclei and a reduction in the DNA content. Quantitative real-time polymerase chain reaction showed that collagen type I expression was significantly higher in the outer mECM group than in the other groups, while collagen type II and aggrecan expression was highest in the inner mECM group. The collagen (hydroxyproline) content was highest in the outer mECM group, while the glycosaminoglycan content was higher in both the inner and outer mECM groups compared with the control group. These results showed that the inner mECM enhances the fibrocartilaginous differentiation of hBMSCs, while the outer mECM promotes a more fibroblastic phenotype. Our findings support the feasibility of fabricating bioactive scaffolds using region-specific mECM preparations for meniscus tissue engineering. This is the first report to demonstrate the feasibility of applying region-specific mECMs for the engineering of meniscus implants capable of reproducing the biphasic, anatomic, and biochemical characteristics of the meniscus, features that should contribute to the feasibility of their clinical application.

76 FR 63654 - Outer Continental Shelf Official Protraction Diagram, Lease Maps, and Supplemental Official Outer...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-13

... Protraction Diagram, Lease Maps, and Supplemental Official Outer Continental Shelf Block Diagrams AGENCY... Supplemental Official OCS Block Diagrams (SOBDs); Correction. SUMMARY: BOEM (formerly the Bureau of Ocean... Official OCS Shelf Block Diagrams'' that contained an error. This notice corrects the address of the Web...

49 CFR 178.338-1 - General requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... outer shell or jacket, with insulation between the inner vessel and outer shell or jacket, and having... specification, tank means inner vessel and jacket means either the outer shell or insulation cover. (c) Each.... (1) Each cargo tank must have an insulation system that will prevent the tank pressure from exceeding...

49 CFR 178.338-1 - General requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... outer shell or jacket, with insulation between the inner vessel and outer shell or jacket, and having... specification, tank means inner vessel and jacket means either the outer shell or insulation cover. (c) Each.... (1) Each cargo tank must have an insulation system that will prevent the tank pressure from exceeding...

49 CFR 178.338-1 - General requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... outer shell or jacket, with insulation between the inner vessel and outer shell or jacket, and having... specification, tank means inner vessel and jacket means either the outer shell or insulation cover. (c) Each.... (1) Each cargo tank must have an insulation system that will prevent the tank pressure from exceeding...

75 FR 20870 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-21

... for Improved Outer Tactical Vests and related accessories under Product Service Code (PSC) 8470 (Armor... granting a waiver of the Nonmanufacturer Rule for Improved Outer Tactical Vests. According to a request, no... Outer Tactical Vests and related accessories under NAICS code 339113, Surgical Appliance and Supplies...

77 FR 4294 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-27

... Activities; Submission to OMB for Review and Approval; Comment Request; Air Pollution Regulations for Outer... electronic docket, go to www.regulations.gov . Title: Air Pollution Regulations for Outer Continental Shelf... Act gives EPA responsibility for regulating air pollution from outer continental shelf (OCS) sources...

9 CFR 355.15 - Inedible material operating and storage rooms; outer premises, docks, driveways, etc.; fly...

Code of Federal Regulations, 2012 CFR

2012-01-01

... storage rooms; outer premises, docks, driveways, etc.; fly-breeding material; nuisances. 355.15 Section....15 Inedible material operating and storage rooms; outer premises, docks, driveways, etc.; fly... departments where certified products are prepared, handled, or stored. Docks and areas where cars and vehicles...

9 CFR 355.15 - Inedible material operating and storage rooms; outer premises, docks, driveways, etc.; fly...

Code of Federal Regulations, 2014 CFR

2014-01-01

... storage rooms; outer premises, docks, driveways, etc.; fly-breeding material; nuisances. 355.15 Section....15 Inedible material operating and storage rooms; outer premises, docks, driveways, etc.; fly... departments where certified products are prepared, handled, or stored. Docks and areas where cars and vehicles...

9 CFR 355.15 - Inedible material operating and storage rooms; outer premises, docks, driveways, etc.; fly...

Code of Federal Regulations, 2013 CFR

2013-01-01

... storage rooms; outer premises, docks, driveways, etc.; fly-breeding material; nuisances. 355.15 Section....15 Inedible material operating and storage rooms; outer premises, docks, driveways, etc.; fly... departments where certified products are prepared, handled, or stored. Docks and areas where cars and vehicles...

[Sulfhydryl group distribution along the axis of the rod outer segment in the frog].

PubMed

Derevianchenko, T G; Fedorovich, I B; Ostrovskiĭ, M A

1985-10-01

The existence of SH-group concentration axial gradient in frog's retinal rod outer segments has been shown. A diminution of SH-groups in the outer segment apical part points to a damage of the vision pigment during the life span of the rod disks.

Dual mode fuel injector with one piece needle valve member

DOEpatents

Lawrence, Keith E.; Hinrichsen, Michael H.; Buckman, Colby

2005-01-18

A fuel injector includes a homogenous charge nozzle outlet set and a conventional nozzle outlet set controlled respectively by inner and outer needle value members. The homogenous charged nozzle outlet set is defined by an outer needle value member that is moveably positioned in an injector body, which defines the conventional nozzle outlet set. The inner needle valve member is positioned in the outer needle valve member. The outer needle valve member is a piece component that includes at least one external guide surface, an external value surface and an internal valve seat.

Pre-stressed/pre-compressed gas turbine nozzle

DOEpatents

Jang, Hoyle; Itzel, Gary Michael; Yu, Yufeng Phillip

2002-01-01

A method of increasing low cycle fatigue life of a turbine nozzle comprising a plurality of stationary airfoils extending between radially inner and outer ring segments comprising a) providing at least one radial passage in each of the plurality of airfoils; b) installing a rod in the radial passage extending between the radially inner and outer ring segments and fixing one end of the rod to one of the inner and outer rings; and c) pre-loading the rod to compress the airfoil between the inner and outer ring segments.

Depletion of the Outer Asteroid Belt

PubMed

Liou; Malhotra

1997-01-17

During the early history of the solar system, it is likely that the outer planets changed their distance from the sun, and hence, their influence on the asteroid belt evolved with time. The gravitational influence of Jupiter and Saturn on the orbital evolution of asteroids in the outer asteroid belt was calculated. The results show that the sweeping of mean motion resonances associated with planetary migration efficiently destabilizes orbits in the outer asteroid belt on a time scale of 10 million years. This mechanism provides an explanation for the observed depletion of asteroids in that region.

Flame holding tolerant fuel and air premixer for a gas turbine combustor

DOEpatents

York, William David; Johnson, Thomas Edward; Ziminsky, Willy Steve

2012-11-20

A fuel nozzle with active cooling is provided. It includes an outer peripheral wall, a nozzle center body concentrically disposed within the outer wall in a fuel and air pre-mixture. The fuel and air pre-mixture includes an air inlet, a fuel inlet and a premixing passage defined between the outer wall in the center body. A gas fuel flow passage is provided. A first cooling passage is included within the center body in a second cooling passage is defined between the center body and the outer wall.

Floating nut retention system

NASA Technical Reports Server (NTRS)

Charles, J. F.; Theakston, H. A. (Inventor)

1980-01-01

A floating nut retention system includes a nut with a central aperture. An inner retainer plate has an opening which is fixedly aligned with the nut aperture. An outer retainer member is formed of a base plate having an opening and a surface adjacent to a surface of the inner retainer plate. The outer retainer member includes a securing mechanism for retaining the inner retainer plate adjacent to the outer retainer member. The securing mechanism enables the inner retainer plate to float with respect to the outer retainer number, while simultaneously forming a bearing surface for inner retainer plate.

Depletion of the Outer Asteroid Belt

NASA Technical Reports Server (NTRS)

Liou, Jer-Chyi; Malhotra, Renu

1997-01-01

During the early history of the solar system, it is likely that the outer planets changed their distance from the sun, and hence, their influence on the asteroid belt evolved with time. The gravitational influence of Jupiter and Saturn on the orbital evolution of asteroids in the outer asteroid belt was calculated. The results show that the sweeping of mean motion resonances associated with planetary migration efficiently destabilizes orbits in the outer asteroid belt on a time scale of 10 million years. This mechanism provides an explanation for the observed depletion of asteroids in that region.

Radioisotope Electric Propulsion for Fast Outer Planetary Orbiters

NASA Technical Reports Server (NTRS)

Oleson, Steven; Benson, Scott; Gefert, Leon; Patterson, Michael; Schreiber, Jeffrey

2002-01-01

Recent interest in outer planetary targets by the Office of Space Science has spurred the search for technology options to enable relatively quick missions to outer planetary targets. Several options are being explored including solar electric propelled stages combined with aerocapture at the target and nuclear electric propulsion. Another option uses radioisotope powered electric thrusters to reach the outer planets. Past work looked at using this technology to provide faster flybys. A better use for this technology is for outer planet orbiters. Combined with medium class launch vehicles and a new direct trajectory these small, sub-kilowatt ion thrusters and Stirling radioisotope generators were found to allow missions as fast as 5 to 12 years for objects from Saturn to Pluto, respectively. Key to the development is light spacecraft and science payload technologies.

Flow rate measurement in a volume

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galvez, Cristhian

A system for measuring flow rate within a volume includes one or more transmission devices that transmit one or more signals through fluid contained within the volume. The volume may be bounded, at least in part, by an outer structure and by an object at least partially contained within the outer structure. A transmission device located at a first location of the outer structure transmits a first signal to a second location of the outer structure. A second signal is transmitted through the fluid from the second location to a third location of the outer structure. The flow rate ofmore » the fluid within the volume may be determined based, at least in part, on the time of flight of both the first signal and the second signal.« less

Alternative irradiation schemes for NIF and LMJ hohlraums

DOE PAGES

Bourgade, Jean-Luc; Bowen, Christopher; Gauthier, Pascal; ...

2017-12-13

Here, we explore two alternative irradiation schemes for the large ('outer') and small ('inner') angle beams that currently illuminate National Ignition Facility (NIF) and Laser Mégajoule cavities. In the first, while the outer laser beams enter through the usual end laser entrance holes (LEH), the inner beams enter through slots along the cavity axis wall, illuminating the back wall of the cavity. This avoids the current interaction of the inner laser beams with the gold wall bubbles generated by the outer beams, which leads to large time-dependent changes in drive symmetry. Another scheme potentially useful for NIF uses only themore » outer beams. The radiative losses through the slots or from the use of outer beams only are compensated by using a smaller cavity and LEH.« less

Alternative irradiation schemes for NIF and LMJ hohlraums

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bourgade, Jean-Luc; Bowen, Christopher; Gauthier, Pascal

Here, we explore two alternative irradiation schemes for the large ('outer') and small ('inner') angle beams that currently illuminate National Ignition Facility (NIF) and Laser Mégajoule cavities. In the first, while the outer laser beams enter through the usual end laser entrance holes (LEH), the inner beams enter through slots along the cavity axis wall, illuminating the back wall of the cavity. This avoids the current interaction of the inner laser beams with the gold wall bubbles generated by the outer beams, which leads to large time-dependent changes in drive symmetry. Another scheme potentially useful for NIF uses only themore » outer beams. The radiative losses through the slots or from the use of outer beams only are compensated by using a smaller cavity and LEH.« less

Magnetic field transfer device and method

DOEpatents

Wipf, S.L.

1990-02-13

A magnetic field transfer device includes a pair of oppositely wound inner coils which each include at least one winding around an inner coil axis, and an outer coil which includes at least one winding around an outer coil axis. The windings may be formed of superconductors. The axes of the two inner coils are parallel and laterally spaced from each other so that the inner coils are positioned in side-by-side relation. The outer coil is outwardly positioned from the inner coils and rotatable relative to the inner coils about a rotational axis substantially perpendicular to the inner coil axes to generate a hypothetical surface which substantially encloses the inner coils. The outer coil rotates relative to the inner coils between a first position in which the outer coil axis is substantially parallel to the inner coil axes and the outer coil augments the magnetic field formed in one of the inner coils, and a second position 180[degree] from the first position, in which the augmented magnetic field is transferred into the other inner coil and reoriented 180[degree] from the original magnetic field. The magnetic field transfer device allows a magnetic field to be transferred between volumes with negligible work being required to rotate the outer coil with respect to the inner coils. 16 figs.

Magnetic field transfer device and method

DOEpatents

Wipf, Stefan L.

1990-01-01

A magnetic field transfer device includes a pair of oppositely wound inner coils which each include at least one winding around an inner coil axis, and an outer coil which includes at least one winding around an outer coil axis. The windings may be formed of superconductors. The axes of the two inner coils are parallel and laterally spaced from each other so that the inner coils are positioned in side-by-side relation. The outer coil is outwardly positioned from the inner coils and rotatable relative to the inner coils about a rotational axis substantially perpendicular to the inner coil axes to generate a hypothetical surface which substantially encloses the inner coils. The outer coil rotates relative to the inner coils between a first position in which the outer coil axis is substantially parallel to the inner coil axes and the outer coil augments the magnetic field formed in one of the inner coils, and a second position 180.degree. from the first position, in which the augmented magnetic field is transferred into the other inner coil and reoriented 180.degree. from the original magnetic field. The magnetic field transfer device allows a magnetic field to be transferred between volumes with negligible work being required to rotate the outer coil with respect to the inner coils.

Cooking utensil with improved heat retention

DOEpatents

Potter, Thomas F.; Benson, David K.; Burch, Steven D.

1997-01-01

A cooking utensil with improved heat retention includes an inner pot received within an outer pot and separated in a closely spaced-apart relationship to form a volume or chamber therebetween. The chamber is evacuated and sealed with foil leaves at the upper edges of the inner and outer pot. The vacuum created between the inner and outer pot, along with the minimum of thermal contact between the inner and outer pot, and the reduced radiative heat transfer due to low emissivity coatings on the inner and outer pot, provide for a highly insulated cooking utensil. Any combination of a plurality of mechanisms for selectively disabling and re-enabling the insulating properties of the pot are provided within the chamber. These mechanisms may include: a hydrogen gas producing and reabsorbing device such as a metal hydride, a plurality of metal contacts which can be adjusted to bridge the gap between the inner and outer pot, and a plurality of bimetallic switches which can selectively bridge the gap between the inner and outer pot. In addition, phase change materials with superior heat retention characteristics may be provided within the cooking utensil. Further, automatic and programmable control of the cooking utensil can be provided through a microprocessor and associated hardware for controlling the vacuum disable/enable mechanisms to automatically cook and save food.

Nose-only exposure system

DOEpatents

Cannon, William C.; Bass, Edward W.; Decker, Jr., John R.

1988-01-01

An exposure system for supplying a gaseous material, i.e. an aerosol, gas or a vapor, directly to the noses of experimental animals includes concentric vertical inner and outer manifolds. The outer manifold connects with the necks of a large number of bottles in which the animals are confined with their noses adjacent the bottle necks. Readily detachable small tubes communicate with the inner manifold and extend to the necks of the bottles. The upper end of the outer manifold and the lower end of the inner manifold are closed. Gaseous material is supplied to the upper end of the inner manifold, flows through the small tubes to points adjacent the noses of the individual animals, then is drawn out through the bottom of the outer manifold. The bottles are readily removable and the device can be disassembled, e.g., for cleaning, by removing the bottles, removing the small tubes, and lifting the inner manifold from the outer manifold. The bottles are supported by engagement of their necks with the outer manifold supplemented, if additional support is required, by individual wire cradles. The outer ends of the bottles are closed by plugs, through which pass metal tubes which receive the tails of the animals (usually rodents) and which serve to dissipate body heat. The entire device is mounted for rotation on turntable bearings.

Differential Response to Heat Stress in Outer and Inner Onion Bulb Scales.

PubMed

Galsurker, Ortal; Doron-Faigenboim, Adi; Teper-Bamnolker, Paula; Daus, Avinoam; Lers, Amnon; Eshel, Dani

2018-05-18

Brown protective skin formation in onion bulbs can be induced by rapid postharvest heat treatment. Onions that were peeled to different depths and were exposed to heat stress showed that only the outer scale formed dry brown skin, whereas the inner scales maintained high water content and did not change color. Our results reveal that browning of the outer scale during heat treatment is due to an enzymatic process that is associated with high levels of oxidation components, such as peroxidase and quercetin glucoside. De-novo transcriptome analysis revealed differential molecular responses of the outer and inner scales to the heat stress. Genes involved in lipid metabolism, oxidation pathways and cell-wall modification were highly expressed in the outer scale during heating. Defense-response-related genes such as those encoding heat-shock proteins, antioxidative stress defense or production of osmoprotectant metabolites were mostly induced in the inner scale in response to the heat exposure. These transcriptomic data led to a conceptual model that suggests sequential processes for browning development and desiccation of the outer scales versus processes associated with defense response and heat tolerance in the inner scale. Thus, the observed physiological differences between the outer and inner scales is supported by the identified molecular differences.

Cooking utensil with improved heat retention

DOEpatents

Potter, T.F.; Benson, D.K.; Burch, S.D.

1997-07-01

A cooking utensil with improved heat retention includes an inner pot received within an outer pot and separated in a closely spaced-apart relationship to form a volume or chamber there between. The chamber is evacuated and sealed with foil leaves at the upper edges of the inner and outer pot. The vacuum created between the inner and outer pot, along with the minimum of thermal contact between the inner and outer pot, and the reduced radiative heat transfer due to low emissivity coatings on the inner and outer pot, provide for a highly insulated cooking utensil. Any combination of a plurality of mechanisms for selectively disabling and re-enabling the insulating properties of the pot are provided within the chamber. These mechanisms may include: a hydrogen gas producing and reabsorbing device such as a metal hydride, a plurality of metal contacts which can be adjusted to bridge the gap between the inner and outer pot, and a plurality of bimetallic switches which can selectively bridge the gap between the inner and outer pot. In addition, phase change materials with superior heat retention characteristics may be provided within the cooking utensil. Further, automatic and programmable control of the cooking utensil can be provided through a microprocessor and associated hardware for controlling the vacuum disable/enable mechanisms to automatically cook and save food. 26 figs.

High-performance, lightweight coaxial cable from carbon nanotube conductors.

PubMed

Jarosz, Paul R; Shaukat, Aalyia; Schauerman, Christopher M; Cress, Cory D; Kladitis, Paul E; Ridgley, Richard D; Landi, Brian J

2012-02-01

Coaxial cables have been constructed with carbon nanotube (CNT) materials serving as both the inner and outer conductors. Treatment of the CNT outer and inner conductors with KAuBr(4) was found to significantly reduce the attenuation of these cables, which demonstrates that chemical agents can be used to improve power transmission through CNT networks at high frequencies (150 kHz-3 GHz). For cables constructed with a KAuBr(4)-treated CNT outer conductor, power attenuation per length approaches parity with cables constructed from metallic conductors at significantly lower weight per length (i.e., 7.1 g/m for CNT designs compared to 38.8 g/m for an RG-58 design). A relationship between the thickness of the CNT outer conductor and the cable attenuation was observed and used to estimate the effective skin depth at high frequency. These results establish reliable, reproducible methods for the construction of coaxial cables from CNT materials that can facilitate further investigation of their performance in high-frequency transmission structures, and highlight a specific opportunity for significant reduction in coaxial cable mass.

Cloning and expression of soluble truncated variants of Borrelia OspA, OspB and Vmp7

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunn, J.J.; Barbour, A.G.

1996-11-05

A method is provided for preparing soluble recombinant variations of Borrelia lipoproteins such as Borrelia burgdorferi outer surface protein A (OspA) and outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The method includes synthesizing a set of oligonucleotide primers, amplifying the template DNA utilizing the PCR, purifying the amplification products, cloning the amplification products into a suitable expression vector, transforming a suitable host utilizing the cloned expression vector, cultivating the transformed host for protein production and subsequently isolating and purifying the resulting protein. Also provided are soluble, recombinant variations of Borrelia burgdorferi outer surface proteinmore » A (OspA), outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The expression vectors harboring DNA encoding the recombinant variations, pET9-OspA, pET9-OspB and pET9-Vmp7, as well as the E. coli host BL21(DE3)/pLysS transformed with each of these vectors, are also disclosed. 38 figs.« less

QATAR-2: A K DWARF ORBITED BY A TRANSITING HOT JUPITER AND A MORE MASSIVE COMPANION IN AN OUTER ORBIT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bryan, Marta L.; Alsubai, Khalid A.; Latham, David W.

We report the discovery and initial characterization of Qatar-2b, a hot Jupiter transiting a V = 13.3 mag K dwarf in a circular orbit with a short period, P{sub b} = 1.34 days. The mass and radius of Qatar-2b are M{sub P} = 2.49 M{sub J} and R{sub P} = 1.14 R{sub J}, respectively. Radial-velocity monitoring of Qatar-2 over a span of 153 days revealed the presence of a second companion in an outer orbit. The Systemic Console yielded plausible orbits for the outer companion, with periods on the order of a year and a companion mass of at leastmore » several M{sub J}. Thus, Qatar-2 joins the short but growing list of systems with a transiting hot Jupiter and an outer companion with a much longer period. This system architecture is in sharp contrast to that found by Kepler for multi-transiting systems, which are dominated by objects smaller than Neptune, usually with tightly spaced orbits that must be nearly coplanar.« less

Convection of Plasmaspheric Plasma into the Outer Magnetosphere and Boundary Layer Region: Initial Results

NASA Technical Reports Server (NTRS)

Ober, Daniel M.; Horwitz, J. L.

1998-01-01

We present initial results on the modeling of the circulation of plasmaspheric-origin plasma into the outer magnetosphere and low-latitude boundary layer (LLBL), using a dynamic global core plasma model (DGCPM). The DGCPM includes the influences of spatially and temporally varying convection and refilling processes to calculate the equatorial core plasma density distribution throughout the magnetosphere. We have developed an initial description of the electric and magnetic field structures in the outer magnetosphere region. The purpose of this paper is to examine both the losses of plasmaspheric-origin plasma into the magnetopause boundary layer and the convection of this plasma that remains trapped on closed magnetic field lines. For the LLBL electric and magnetic structures we have adopted here, the plasmaspheric plasma reaching the outer magnetosphere is diverted anti-sunward primarily along the dusk flank. These plasmas reach X= -15 R(sub E) in the LLBL approximately 3.2 hours after the initial enhancement of convection and continues to populate the LLBL for 12 hours as the convection electric field diminishes.

Identification of Major Outer Surface Proteins of Streptococcus agalactiae

PubMed Central

Hughes, Martin J. G.; Moore, Joanne C.; Lane, Jonathan D.; Wilson, Rebecca; Pribul, Philippa K.; Younes, Zabin N.; Dobson, Richard J.; Everest, Paul; Reason, Andrew J.; Redfern, Joanne M.; Greer, Fiona M.; Paxton, Thanai; Panico, Maria; Morris, Howard R.; Feldman, Robert G.; Santangelo, Joseph D.

2002-01-01

To identify the major outer surface proteins of Streptococcus agalactiae (group B streptococcus), a proteomic analysis was undertaken. An extract of the outer surface proteins was separated by two-dimensional electrophoresis. The visualized spots were identified through a combination of peptide sequencing and reverse genetic methodologies. Of the 30 major spots identified as S. agalactiae specific, 27 have been identified. Six of these proteins, previously unidentified in S. agalactiae, were sequenced and cloned. These were ornithine carbamoyltransferase, phosphoglycerate kinase, nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase, purine nucleoside phosphorylase, enolase, and glucose-6-phosphate isomerase. Using a gram-positive expression system, we have overexpressed two of these proteins in an in vitro system. These recombinant, purified proteins were used to raise antisera. The identification of these proteins as residing on the outer surface was confirmed by the ability of the antisera to react against whole, live bacteria. Further, in a neonatal-animal model system, we demonstrate that some of these sera are protective against lethal doses of bacteria. These studies demonstrate the successful application of proteomics as a technique for identifying vaccine candidates. PMID:11854208

Cloning and expression of soluble truncated variants of Borrelia OspA, OspB and Vmp7

DOEpatents

Dunn, John J.; Barbour, Alan G.

1996-11-05

A method is provided herein for preparing soluble recombinant variations of Borrelia lipoproteins such as Borrelia burgdorferi outer surface protein A (OspA) and outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The method includes synthesizing a set of oligonucleotide primers, amplifying the template DNA utilizing the PCR, purifying the amplification products, cloning the amplification products into a suitable expression vector, transforming a suitable host utilizing the cloned expression vector, cultivating the transformed host for protein production and subsequently isolating and purifying the resulting protein. Also provided are soluble, recombinant variations of Borrelia burgdorferi outer surface protein A (OspA), outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The expression vectors harboring DNA encoding the recombinant variations, pET9-OspA, pET9-OspB and pET9-Vmp7, as well as the E. coli host BL21(DE3)/pLysS transformed with each of these vectors, are also disclosed.

Cloning and expression of soluble truncated variants of Borrelia OspA, OspB and Vmp7

DOEpatents

Dunn, J.J.; Barbour, A.G.

1996-11-05

A method is provided for preparing soluble recombinant variations of Borrelia lipoproteins such as Borrelia burgdorferi outer surface protein A (OspA) and outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The method includes synthesizing a set of oligonucleotide primers, amplifying the template DNA utilizing the PCR, purifying the amplification products, cloning the amplification products into a suitable expression vector, transforming a suitable host utilizing the cloned expression vector, cultivating the transformed host for protein production and subsequently isolating and purifying the resulting protein. Also provided are soluble, recombinant variations of Borrelia burgdorferi outer surface protein A (OspA), outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The expression vectors harboring DNA encoding the recombinant variations, pET9-OspA, pET9-OspB and pET9-Vmp7, as well as the E. coli host BL21(DE3)/pLysS transformed with each of these vectors, are also disclosed. 38 figs.

Sputtering of ices in the outer solar system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, R.E.

1996-01-01

Exploration of the outer solar system has led to studies in a new area of physics: electronically induced sputtering of low-temperature, condensed-gas solids (ices). Many of the icy bodies in the outer solar system were found to be bombarded by relatively intense fluxes of ions and electrons, causing both changes in their optical reflectance and ejection (sputtering) of molecules from their surfaces. The small cohesive energies of the condensed-gas solids afford relatively large sputtering rates from the electronic excitations produced in the solid by fast ions and electrons. Such sputtering produces an ambient gas about an icy body, often themore » source of the local plasma. This colloquium outlines the physics of the sputtering of ices and its relevance to several outer-solar-system phenomena: the sputter-produced plasma trapped in Saturn{close_quote}s magnetosphere; the O{sub 2} atmosphere on Europa; and optical absorption features such as SO{sub 2} in the surface of Europa and O{sub 2} and, possibly, O{sub 3} in the surface of Ganymede. {copyright} {ital 1996 The American Physical Society.}« less

Characterization of N-linked oligosaccharides assembled on secretory recombinant glucose oxidase and cell wall mannoproteins from the methylotrophic yeast Hansenula polymorpha.

PubMed

Kim, Moo Woong; Rhee, Sang Ki; Kim, Jeong-Yoon; Shimma, Yoh-ichi; Chiba, Yasunori; Jigami, Yoshifumi; Kang, Hyun Ah

2004-03-01

Presently almost no information is available on the oligosaccharide structure of the glycoproteins secreted from the methylotrophic yeast Hansenula polymorpha, a promising host for the production of recombinant proteins. In this study, we analyze the size distribution and structure of N-linked oligosaccharides attached to the recombinant glycoprotein glucose oxidase (GOD) and the cell wall mannoproteins obtained from H. polymorpha. Oligosaccharide profiling showed that the major oligosaccharide species derived from the H. polymorpha-secreted recombinant GOD (rGOD) had core-type structures (Man(8-12)GlcNAc(2)). Analyses using anti-alpha 1,3-mannose antibody and exoglycosidases specific for alpha 1,2- or alpha 1,6-mannose linkages revealed that the mannose outer chains of N-glycans on the rGOD have very short alpha 1,6 extensions and are mainly elongated in alpha 1,2-linkages without a terminal alpha 1,3-linked mannose addition. The N-glycans released from the H. polymorpha mannoproteins were shown to contain mostly mannose in their outer chains, which displayed almost identical size distribution and structure to those of H. polymorpha-derived rGOD. These results strongly indicate that the outer chain processing of N-glycans by H. polymorpha significantly differs from that by Saccharomyces cerevisiae, thus generating much shorter mannose outer chains devoid of terminal alpha 1,3-linked mannoses.

Dynamical evolution of V-type photometric candidates in the central and outer main belt asteroids

NASA Astrophysics Data System (ADS)

Carruba, V.; Huaman, M.

2014-07-01

V-type asteroids are associated with basaltic composition, and are supposed to be fragments of crust of differentiated objects. Most V-type asteroids in the main belt are found in the inner main belt, and are either current members of the Vesta dynamical family (Vestoids), or past members that drifted away. However, several V-type photometric candidates have been recently identified in the central and outer main belt. The origin of this large population of V-type objects is not well understood, since it seems unlikely that Vestoids crossing the 3:1 and 5:2 mean-motion resonance with Jupiter could account for the whole observed population. In this work, we investigated a possible origin of the bodies from local sources, such as the parent bodies of the Eunomia, Merxia, and Agnia asteroid families in the central main belt, and Dembowska, Eos and Magnya asteroid families in the outer main belt. Our results show that dynamical evolution from the parent bodies of the Eunomia and Merxia/Agnia families on timescales of 2 Gyr or more could be responsible for the current orbital location of most of the V-type photometric candidates in the central main belt. Studies for the outer main belt are currently in progress. by the FAPESP (grant 2011/19863-3) and CAPES (grant 15029-12-3) funding agencies.

Proceedings: Outer Planet Probe Technology Workshop, summary volume

NASA Technical Reports Server (NTRS)

1974-01-01

A summary report and overview of the Outer Planet Probe Technology Conference are given. Summary data cover: (1) state of the art concerning mission definitions, probe requirements, systems, subsystems, and mission peculiar hardware, (2) mission and equipment trade-offs associated with Saturn/Uranus baseline configuration and the influence of Titan and Jupiter options on mission performance and costs, and (3) identification of critically required future R and D activities.

Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells.

PubMed

Wahlin, Karl J; Maruotti, Julien A; Sripathi, Srinivasa R; Ball, John; Angueyra, Juan M; Kim, Catherine; Grebe, Rhonda; Li, Wei; Jones, Bryan W; Zack, Donald J

2017-04-10

The retinal degenerative diseases, which together constitute a leading cause of hereditary blindness worldwide, are largely untreatable. Development of reliable methods to culture complex retinal tissues from human pluripotent stem cells (hPSCs) could offer a means to study human retinal development, provide a platform to investigate the mechanisms of retinal degeneration and screen for neuroprotective compounds, and provide the basis for cell-based therapeutic strategies. In this study, we describe an in vitro method by which hPSCs can be differentiated into 3D retinas with at least some important features reminiscent of a mature retina, including exuberant outgrowth of outer segment-like structures and synaptic ribbons, photoreceptor neurotransmitter expression, and membrane conductances and synaptic vesicle release properties consistent with possible photoreceptor synaptic function. The advanced outer segment-like structures reported here support the notion that 3D retina cups could serve as a model for studying mature photoreceptor development and allow for more robust modeling of retinal degenerative disease in vitro.

Solar System Exploration Augmented by Lunar and Outer Planet Resource Utilization: Historical Perspectives and Future Possibilities

NASA Technical Reports Server (NTRS)

Palaszewski, Bryan

2014-01-01

Establishing a lunar presence and creating an industrial capability on the Moon may lead to important new discoveries for all of human kind. Historical studies of lunar exploration, in-situ resource utilization (ISRU) and industrialization all point to the vast resources on the Moon and its links to future human and robotic exploration. In the historical work, a broad range of technological innovations are described and analyzed. These studies depict program planning for future human missions throughout the solar system, lunar launched nuclear rockets, and future human settlements on the Moon, respectively. Updated analyses based on the visions presented are presented. While advanced propulsion systems were proposed in these historical studies, further investigation of nuclear options using high power nuclear thermal propulsion, nuclear surface power, as well as advanced chemical propulsion can significantly enhance these scenarios. Robotic and human outer planet exploration options are described in many detailed and extensive studies. Nuclear propulsion options for fast trips to the outer planets are discussed. To refuel such vehicles, atmospheric mining in the outer solar system has also been investigated as a means of fuel production for high energy propulsion and power. Fusion fuels such as Helium 3 (3He) and hydrogen can be wrested from the atmospheres of Uranus and Neptune and either returned to Earth or used in-situ for energy production. Helium 3 and hydrogen (deuterium, etc.) were the primary gases of interest with hydrogen being the primary propellant for nuclear thermal solid core and gas core rocket-based atmospheric flight. A series of analyses have investigated resource capturing aspects of atmospheric mining in the outer solar system. These analyses included the gas capturing rate, storage options, and different methods of direct use of the captured gases. While capturing 3He, large amounts of hydrogen and 4He are produced. With these two additional gases, the potential for fueling small and large fleets of additional exploration and exploitation vehicles exists.

Solar System Exploration Augmented by Lunar and Outer Planet Resource Utilization: Historical Perspectives and Future Possibilities

NASA Technical Reports Server (NTRS)

Palaszewski, Bryan

2014-01-01

Establishing a lunar presence and creating an industrial capability on the Moon may lead to important new discoveries for all of human kind. Historical studies of lunar exploration, in-situ resource utilization (ISRU) and industrialization all point to the vast resources on the Moon and its links to future human and robotic exploration. In the historical work, a broad range of technological innovations are described and analyzed. These studies depict program planning for future human missions throughout the solar system, lunar launched nuclear rockets, and future human settlements on the Moon, respectively. Updated analyses based on the visions presented are presented. While advanced propulsion systems were proposed in these historical studies, further investigation of nuclear options using high power nuclear thermal propulsion, nuclear surface power, as well as advanced chemical propulsion can significantly enhance these scenarios. Robotic and human outer planet exploration options are described in many detailed and extensive studies. Nuclear propulsion options for fast trips to the outer planets are discussed. To refuel such vehicles, atmospheric mining in the outer solar system has also been investigated as a means of fuel production for high energy propulsion and power. Fusion fuels such as helium 3 (3He) and hydrogen (H2) can be wrested from the atmospheres of Uranus and Neptune and either returned to Earth or used in-situ for energy production. Helium 3 and H2 (deuterium, etc.) were the primary gases of interest with hydrogen being the primary propellant for nuclear thermal solid core and gas core rocket-based atmospheric flight. A series of analyses have investigated resource capturing aspects of atmospheric mining in the outer solar system. These analyses included the gas capturing rate, storage options, and different methods of direct use of the captured gases. While capturing 3He, large amounts of hydrogen and 4He are produced. With these two additional gases, the potential for fueling small and large fleets of additional exploration and exploitation vehicles exists.

Le concept suédois pour stockage définitif des déchets nucléaires

NASA Astrophysics Data System (ADS)

Hedman, Tommy; Nyström, Anders; Thegerström, Claes

2002-10-01

The purpose of a disposal is to isolate the radioactive waste from man and the environment. If the isolation is broken, the leakage and transport of radioactive substances must be retarded. The package is one of several barriers, used to achieve these two main functions. For short-lived, low and intermediate level waste four standard containers of steel and concrete are used. Spent fuel will be placed in a canister consisting of a pressure-bearing insert of cast nodular iron and an outer corrosion barrier of copper before it is deposited in a deep geological repository. In particular, the development of a high integrity copper canister for the isolation of spent nuclear fuel is described in this paper. To cite this article: T. Hedman et al., C. R. Physique 3 (2002) 903-913.

78 FR 1759 - Notice of Approval of Clean Air Act Outer Continental Shelf Minor Source/Title V Minor Permit...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-09

... Outer Continental Shelf Minor Source/Title V Minor Permit Modification Issued to Shell Offshore, Inc. for the Kulluk Conical Drilling Unit AGENCY: United States Environmental Protection Agency (EPA... decision granting Shell Offshore Inc.'s (``Shell'') request for minor modifications of Clean Air Act Outer...

77 FR 61633 - Information Collection: Renewable Energy and Alternate Uses of Existing Facilities on the Outer...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-10

...] Information Collection: Renewable Energy and Alternate Uses of Existing Facilities on the Outer Continental... requirements in the regulations under ``Renewable Energy and Alternate Uses of Existing Facilities on the Outer..., transportation, or transmission of energy from sources other than oil and gas (renewable energy). Specifically...

77 FR 24980 - Notice on Outer Continental Shelf Oil and Gas Lease Sales

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-26

... DEPARTMENT OF THE INTERIOR Bureau of Ocean Energy Management Notice on Outer Continental Shelf Oil... Outer Continental Shelf oil and gas lease sales to be held during the bidding period May 1, 2012... Corporation ExxonMobil Exploration Company Group II. Shell Oil Company Shell Offshore Inc. SWEPI LP Shell...

30 CFR 256.0 - Authority for information collection.

Code of Federal Regulations, 2011 CFR

2011-07-01

... OF THE INTERIOR OFFSHORE LEASING OF SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Oil, Gas, and Sulphur Management, General § 256.0 Authority for information collection. (a... information collection is “30 CFR part 256, Leasing of Sulphur or Oil and Gas in the Outer Continental Shelf...

77 FR 15118 - Information Collection Activities: Operations in the Outer Continental Shelf for Minerals Other...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-14

...-0005; OMB Number 1014-NEW] Information Collection Activities: Operations in the Outer Continental Shelf for Minerals Other Than Oil, Gas, and Sulphur; Submitted for Office of Management and Budget (OMB... (ICR) for approval of the paperwork requirements in the regulations under Operations in the Outer...

75 FR 82055 - Commercial Leasing for Wind Power on the Outer Continental Shelf (OCS) Offshore Massachusetts...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-29

... No. BOEM-2010-0063] Commercial Leasing for Wind Power on the Outer Continental Shelf (OCS) Offshore..., Interior. ACTION: RFI in Commercial Wind Energy Leasing Offshore Massachusetts, and Invitation for Comments... the construction of a wind energy project(s) on the Outer Continental Shelf (OCS) offshore...

46 CFR 154.170 - Outer hull steel plating.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 5 2010-10-01 2010-10-01 false Outer hull steel plating. 154.170 Section 154.170... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Hull Structure § 154.170 Outer hull steel plating. (a) Except as required in paragraph (b) of this section, the...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Groenendaal, J.C. Jr.; Anemone, J.J.

This patent describes low pressure steam turbine apparatus having inner and outer cylinders, the outer cylinder having a support shelf, and inner cylinder support means for providing flexible support of the inner cylinder on the outer cylinder. It comprises: a horizontal joint flange and at least one support foot integrally connected thereto which projects substantially radially outward form the horizontal joint flange.

78 FR 40394 - Safety Zone; Outer Banks Bluegrass Festival; Shallowbag Bay, Manteo, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-05

...-AA00 Safety Zone; Outer Banks Bluegrass Festival; Shallowbag Bay, Manteo, NC AGENCY: Coast Guard, DHS... Festival. This action is necessary to protect the life and property of the maritime public from the hazards... Shallowbag Bay River during the Outer Banks Bluegrass Festival Fireworks display. DATES: This rule is...

75 FR 45195 - Office of Hazardous Materials Safety; Notice of Applications for Modification of Special Permit

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-02

... compressed oxygen without rigid outer packaging when no other means of transportation exist. 14860-M Alaska... authorizing the transportation in commerce of compressed oxygen without rigid outer packaging when no other... transportation in commerce of compressed oxygen without rigid outer packaging when no other means of...

Fine tuning the ionic liquid-vacuum outer atomic surface using ion mixtures.

PubMed

Villar-Garcia, Ignacio J; Fearn, Sarah; Ismail, Nur L; McIntosh, Alastair J S; Lovelock, Kevin R J

2015-03-28

Ionic liquid-vacuum outer atomic surfaces can be created that are remarkably different from the bulk composition. In this communication we demonstrate, using low-energy ion scattering (LEIS), that for ionic liquid mixtures the outer atomic surface shows significantly more atoms from anions with weaker cation-anion interactions (and vice versa).

19 CFR 10.41b - Clearance of serially numbered substantial holders or outer containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... or outer containers. 10.41b Section 10.41b Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... holders or outer containers. (a) The holders and containers described in this section may be released... intermodal and similar containers or containers which are themselves vehicles or vehicle appurtenances and...

19 CFR 10.41b - Clearance of serially numbered substantial holders or outer containers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... or outer containers. 10.41b Section 10.41b Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... holders or outer containers. (a) The holders and containers described in this section may be released... intermodal and similar containers or containers which are themselves vehicles or vehicle appurtenances and...

19 CFR 10.41b - Clearance of serially numbered substantial holders or outer containers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... or outer containers. 10.41b Section 10.41b Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... holders or outer containers. (a) The holders and containers described in this section may be released... intermodal and similar containers or containers which are themselves vehicles or vehicle appurtenances and...

19 CFR 10.41b - Clearance of serially numbered substantial holders or outer containers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... or outer containers. 10.41b Section 10.41b Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... holders or outer containers. (a) The holders and containers described in this section may be released... intermodal and similar containers or containers which are themselves vehicles or vehicle appurtenances and...

19 CFR 10.41b - Clearance of serially numbered substantial holders or outer containers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... or outer containers. 10.41b Section 10.41b Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... holders or outer containers. (a) The holders and containers described in this section may be released... intermodal and similar containers or containers which are themselves vehicles or vehicle appurtenances and...

78 FR 67326 - Safety and Environmental Management System Requirements for Vessels on the U.S. Outer Continental...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-12

... 1625-AC05 Safety and Environmental Management System Requirements for Vessels on the U.S. Outer... ``Safety and Environmental Management System Requirements for Vessels on the U.S. Outer Continental Shelf... of industry to ensure stakeholders have adequate time to submit complete responses. DATES: Comments...

Flow field and dissolved oxygen distributions in the outer channel of the Orbal oxidation ditch by monitor and CFD simulation.

PubMed

Guo, Xuesong; Zhou, Xin; Chen, Qiuwen; Liu, Junxin

2013-04-01

In the Orbal oxidation ditch, denitrification is primarily accomplished in the outer channel. However, the detailed characteristics of the flow field and dissolved oxygen (DO) distribution in the outer channel are not well understood. Therefore, in this study, the flow velocity and DO concentration in the outer channel of an Orbal oxidation ditch system in a wastewater treatment plant in Beijing (China) were monitored under actual operation conditions. The flow field and DO concentration distributions were analyzed by computed fluid dynamic modeling. In situ monitoring and modeling both showed that the flow velocity was heterogeneous in the outer channel. As a result, the DO was also heterogeneously distributed in the outer channel, with concentration gradients occurring along the flow direction as well as in the cross-section. This heterogeneous DO distribution created many anoxic and aerobic zones, which may have facilitated simultaneous nitrification-denitrification in the channel. These findings may provide supporting information for rational optimization of the performance of the Orbal oxidation ditch.

Seamless metal-clad fiber-reinforced organic matrix composite structures and process for their manufacture

NASA Technical Reports Server (NTRS)

Bluck, Raymond M. (Inventor); Bush, Harold G. (Inventor); Johnson, Robert R. (Inventor)

1990-01-01

A metallic outer sleeve is provided which is capable of enveloping a hollow metallic inner member having continuous reinforcing fibers attached to the distal end thereof. The inner member is then introduced into outer sleeve until inner member is completely enveloped by outer sleeve. A liquid matrix member is then injected into space between inner member and outer sleeve. A pressurized heat transfer medium is flowed through the inside of inner member, thereby forming a fiber reinforced matrix composite material. The wall thicknesses of both inner member and outer sleeve are then reduced to the appropriate size by chemical etching, to adjust the thermal expansion coefficient of the metal-clad composite structure to the desired value. thereby forming a fiber reinforced matrix composite material. The wall thicknesses of both inner member and outer sleeve are then reduced to the appropriate size by chemical etching, to adjust the thermal expansion coefficient of the metal-clad composite structure to the desired value. The novelty of this invention resides in the development of a efficient method of producing seamless metal clad fiber reinforced organic matrix composite structures.

Heat pump water heater and method of making the same

DOEpatents

Mei, Viung C.; Tomlinson, John J.; Chen, Fang C.

2001-01-01

An improved heat pump water heater wherein the condenser assembly of the heat pump is inserted into the water tank through an existing opening in the top of the tank, the assembly comprising a tube-in-a-tube construction with an elongated cylindrical outer body heat exchanger having a closed bottom with the superheated refrigerant that exits the compressor of the heat pump entering the top of the outer body. As the refrigerant condenses along the interior surface of the outer body, the heat from the refrigerant is transferred to the water through the outer body. The refrigerant then enters the bottom of an inner body coaxially disposed within the outer body and exits the top of the inner body into the refrigerant conduit leading into the expansion device of the heat pump. The outer body, in a second embodiment of the invention, acts not only as a heat exchanger but also as the sacrificial anode in the water tank by being constructed of a metal which is more likely to corrode than the metal of the tank.

Usher syndrome type 1–associated cadherins shape the photoreceptor outer segment

PubMed Central

Parain, Karine; Aghaie, Asadollah; Picaud, Serge

2017-01-01

Usher syndrome type 1 (USH1) causes combined hearing and sight defects, but how mutations in USH1 genes lead to retinal dystrophy in patients remains elusive. The USH1 protein complex is associated with calyceal processes, which are microvilli of unknown function surrounding the base of the photoreceptor outer segment. We show that in Xenopus tropicalis, these processes are connected to the outer-segment membrane by links composed of protocadherin-15 (USH1F protein). Protocadherin-15 deficiency, obtained by a knockdown approach, leads to impaired photoreceptor function and abnormally shaped photoreceptor outer segments. Rod basal outer disks displayed excessive outgrowth, and cone outer segments were curved, with lamellae of heterogeneous sizes, defects also observed upon knockdown of Cdh23, encoding cadherin-23 (USH1D protein). The calyceal processes were virtually absent in cones and displayed markedly reduced F-actin content in rods, suggesting that protocadherin-15–containing links are essential for their development and/or maintenance. We propose that calyceal processes, together with their associated links, control the sizing of rod disks and cone lamellae throughout their daily renewal. PMID:28495838

Usher syndrome type 1-associated cadherins shape the photoreceptor outer segment.

PubMed

Schietroma, Cataldo; Parain, Karine; Estivalet, Amrit; Aghaie, Asadollah; Boutet de Monvel, Jacques; Picaud, Serge; Sahel, José-Alain; Perron, Muriel; El-Amraoui, Aziz; Petit, Christine

2017-06-05

Usher syndrome type 1 (USH1) causes combined hearing and sight defects, but how mutations in USH1 genes lead to retinal dystrophy in patients remains elusive. The USH1 protein complex is associated with calyceal processes, which are microvilli of unknown function surrounding the base of the photoreceptor outer segment. We show that in Xenopus tropicalis , these processes are connected to the outer-segment membrane by links composed of protocadherin-15 (USH1F protein). Protocadherin-15 deficiency, obtained by a knockdown approach, leads to impaired photoreceptor function and abnormally shaped photoreceptor outer segments. Rod basal outer disks displayed excessive outgrowth, and cone outer segments were curved, with lamellae of heterogeneous sizes, defects also observed upon knockdown of Cdh23 , encoding cadherin-23 (USH1D protein). The calyceal processes were virtually absent in cones and displayed markedly reduced F-actin content in rods, suggesting that protocadherin-15-containing links are essential for their development and/or maintenance. We propose that calyceal processes, together with their associated links, control the sizing of rod disks and cone lamellae throughout their daily renewal. © 2017 Schietroma et al.

Conductor load bearing roller for a gas-insulated transmission line having a corrugated outer conductor

DOEpatents

Fischer, William H.; Yoon, Kue H.

1984-04-10

A gas-insulated transmission line includes a corrugated outer conductor, an inner conductor disposed within and insulated from the outer conductor by means of support insulators and an insulating gas, and a transport device for supporting and permitting movement of the inner conductor/insulating support assembly axially along the corrugated outer conductor without radial displacement. The transport device includes two movable contacts, such as skids or rollers, supported on a common pivot lever, the pivot lever being rotatably disposed about a pivot lever axis, which pivot lever axis is in turn disposed on the periphery of a support insulator or particle trap if one is used. The movable contacts are separated axially a distance equal to the axial distance between the peaks and valleys of the corrugations of the outer conductor and separated radially a distance equal to the radial distance between the peaks and valleys of the corrugations of the outer conductor. The transport device has the pivot lever axis disposed perpendicular to the direction of travel of the inner conductor/insulating support assembly.

Recent developments on SU UMa stars - theory vs. observation

NASA Astrophysics Data System (ADS)

Cannizzo, John K.

2015-01-01

Kepler light curves of short period dwarf novae have resparked interest in the nature of superoutbursts and led to the question: Is the thermal-tidal instability needed, or can the plain vanilla version of the accretion disk limit cycle do the job all by itself? A detailed time-resolved study of an eclipsing SU UMa system during superoutburst onset should settle the question - if there is a dramatic contraction of the disk at superoutburst onset, Osaki's thermal-tidal model would be preferred; if not, the plain disk instability model would be sufficient. I will present recent results that support the contention by Osaki & Kato that the time varying negative superhump frequencies can be taken as a surrogate for the outer disk radius variations. Finally, it may be necessaryto look beyond the short period dwarf novae to gain perspective on the nature of embedded precursors in long outbursts.

Measuring the Density of States of the Inner and Outer Wall of Double-Walled Carbon Nanotubes.

PubMed

Chambers, Benjamin A; Shearer, Cameron J; Yu, LePing; Gibson, Christopher T; Andersson, Gunther G

2018-06-19

The combination of ultraviolet photoelectron spectroscopy and metastable helium induced electron spectroscopy is used to determine the density of states of the inner and outer coaxial carbon nanotubes. Ultraviolet photoelectron spectroscopy typically measures the density of states across the entire carbon nanotube, while metastable helium induced electron spectroscopy measures the density of states of the outermost layer alone. The use of double-walled carbon nanotubes in electronic devices allows for the outer wall to be functionalised whilst the inner wall remains defect free and the density of states is kept intact for electron transport. Separating the information of the inner and outer walls enables development of double-walled carbon nanotubes to be independent, such that the charge transport of the inner wall is maintained and confirmed whilst the outer wall is modified for functional purposes.

Inner and Outer Recursive Neural Networks for Chemoinformatics Applications.

PubMed

Urban, Gregor; Subrahmanya, Niranjan; Baldi, Pierre

2018-02-26

Deep learning methods applied to problems in chemoinformatics often require the use of recursive neural networks to handle data with graphical structure and variable size. We present a useful classification of recursive neural network approaches into two classes, the inner and outer approach. The inner approach uses recursion inside the underlying graph, to essentially "crawl" the edges of the graph, while the outer approach uses recursion outside the underlying graph, to aggregate information over progressively longer distances in an orthogonal direction. We illustrate the inner and outer approaches on several examples. More importantly, we provide open-source implementations [available at www.github.com/Chemoinformatics/InnerOuterRNN and cdb.ics.uci.edu ] for both approaches in Tensorflow which can be used in combination with training data to produce efficient models for predicting the physical, chemical, and biological properties of small molecules.

Gas turbine structural mounting arrangement between combustion gas duct annular chamber and turbine vane carrier

DOEpatents

Wiebe, David J.; Charron, Richard C.; Morrison, Jay A.

2016-10-18

A gas turbine engine ducting arrangement (10), including: an annular chamber (14) configured to receive a plurality of discrete flows of combustion gases originating in respective can combustors and to deliver the discrete flows to a turbine inlet annulus, wherein the annular chamber includes an inner diameter (52) and an outer diameter (60); an outer diameter mounting arrangement (34) configured to permit relative radial movement and to prevent relative axial and circumferential movement between the outer diameter and a turbine vane carrier (20); and an inner diameter mounting arrangement (36) including a bracket (64) secured to the turbine vane carrier, wherein the bracket is configured to permit the inner diameter to move radially with the outer diameter and prevent axial deflection of the inner diameter with respect to the outer diameter.

Skin Friction Reduction by Micro-Blowing Technique

NASA Technical Reports Server (NTRS)

Hwang, Danny P. (Inventor)

1998-01-01

A system and method for reducing skin friction of an object in relative motion to a fluid. A skin forming a boundary between the object and the fluid, the skin having holes through which micro-blowing of air is blown and a transmitting mechanism for transmitting air through the skin. The skin has an inner layer and an outer layer. the inner layer being a low permeable porous sheet, the outer layer being a plate having high aspect ratio high porosity. and small holes. The system may further include a suction apparatus for suctioning air from the outer layer. The method includes the steps of transmitting air through the inner layer and passing the air transmitted through the inner layer to the outer layer. The method may further include the step of bleeding air off the outer layer using the suction apparatus.

Power inverters

DOEpatents

Miller, David H [Redondo Beach, CA; Korich, Mark D [Chino Hills, CA; Smith, Gregory S [Woodland Hills, CA

2011-11-15

Power inverters include a frame and a power module. The frame has a sidewall including an opening and defining a fluid passageway. The power module is coupled to the frame over the opening and includes a substrate, die, and an encasement. The substrate includes a first side, a second side, a center, an outer periphery, and an outer edge, and the first side of the substrate comprises a first outer layer including a metal material. The die are positioned in the substrate center and are coupled to the substrate first side. The encasement is molded over the outer periphery on the substrate first side, the substrate second side, and the substrate outer edge and around the die. The encasement, coupled to the substrate, forms a seal with the metal material. The second side of the substrate is positioned to directly contact a fluid flowing through the fluid passageway.

Premixed direct injection nozzle for highly reactive fuels

DOEpatents

Ziminsky, Willy Steve; Johnson, Thomas Edward; Lacy, Benjamin Paul; York, William David; Uhm, Jong Ho; Zuo, Baifang

2013-09-24

A fuel/air mixing tube for use in a fuel/air mixing tube bundle is provided. The fuel/air mixing tube includes an outer tube wall extending axially along a tube axis between an inlet end and an exit end, the outer tube wall having a thickness extending between an inner tube surface having a inner diameter and an outer tube surface having an outer tube diameter. The tube further includes at least one fuel injection hole having a fuel injection hole diameter extending through the outer tube wall, the fuel injection hole having an injection angle relative to the tube axis. The invention provides good fuel air mixing with low combustion generated NOx and low flow pressure loss translating to a high gas turbine efficiency, that is durable, and resistant to flame holding and flash back.

Semi-flexible gas-insulated transmission line using protection tube in conductor plug-in joint

DOEpatents

Kommineni, P.R.

1983-01-25

A gas-insulated transmission line includes an outer sheath, an inner conductor, an insulating gas electrically insulating the inner conductor from the outer sheath, and insulating supports insulatably supporting the inner conductor within the outer sheath. The inner conductor is provided with flexibility by main conductor sections which are joined together through a conductor hub section and flexible flexing elements. Stress shields are provided to control the electric field at the locations of the conductor hub sections where the insulating supports are contacting the inner conductor. A plug and socket arrangement is utilized for joining adjacent sections of the inner conductor, and a protection tube is utilized inside the hollow plug to maintain proper alignment of the joint when the transmission line is bent. 3 figs.

In situ spectroscopic evidence for neptunium(V)-carbonate inner-sphere and outer-sphere ternary surface complexes on hematite surfaces.

PubMed

Arai, Yuji; Moran, P B; Honeyman, B D; Davis, J A

2007-06-01

Np(V) surface speciation on hematite surfaces at pH 7-9 under pC2 = 10(-3.45) atm was investigated using X-ray absorption spectroscopy (XAS). In situ XAS analyses suggest that bis-carbonato inner-sphere and tris-carbonato outer-sphere ternary surface species coexist at the hematite-water interface at pH 7-8.8, and the fraction of outer-sphere species gradually increases from 27 to 54% with increasing pH from 7 to 8.8. The results suggest that the heretofore unknown Np(V)-carbonato ternary surface species may be important in predicting the fate and transport of Np(V) in the subsurface environment down gradient of high-level nuclear waste respositories.

The Width of a Solar Coronal Mass Ejection and the Source of the Driving Magnetic Explosion

NASA Technical Reports Server (NTRS)

Moore, Ronald L.; Sterling, Alphonse C.; Suess, Steven T.

2007-01-01

We show that the strength of the magnetic field in the area covered by the flare arcade following a CME-producing ejective solar eruption can be estimated from the final angular width of the CME in the outer corona and the final angular width of the flare arcade. We assume (1) the flux-rope plasmoid ejected from the flare site becomes the interior of the CME plasmoid, (2) in the outer corona (R greater than 2R(sub Sun)) the CME is roughly a spherical plasmoid with legs shaped like a light bulb, and (3) beyond some height in or below the outer corona the CME plasmoid is in lateral pressure balance with the surrounding magnetic field. The strength of the nearly radial magnetic field in the outer corona is estimated from the radial component of the interplanetary magnetic field measured by Ulysses. We apply this model to three well-observed CMEs that exploded from flare regions of extremely different size and magnetic setting. One of these CMEs is an over-and-out CME that exploded from a laterally far offset compact ejective flare. In each event, the estimated source-region field strength is appropriate for the magnetic setting of the flare. This agreement (1) indicates that CMEs are propelled by the magnetic field of the CME plasmoid pushing against the surrounding magnetic field, (2) supports the magnetic-arch-blowout scenario for over-and-out CMEs, and (3) shows that a CME s final angular width in the outer corona can be estimated from the amount of magnetic flux covered by the source-region flare arcade.

RefMoB, a Reflectivity Feature Model-Based Automated Method for Measuring Four Outer Retinal Hyperreflective Bands in Optical Coherence Tomography

PubMed Central

Ross, Douglas H.; Clark, Mark E.; Godara, Pooja; Huisingh, Carrie; McGwin, Gerald; Owsley, Cynthia; Litts, Katie M.; Spaide, Richard F.; Sloan, Kenneth R.; Curcio, Christine A.

2015-01-01

Purpose. To validate a model-driven method (RefMoB) of automatically describing the four outer retinal hyperreflective bands revealed by spectral-domain optical coherence tomography (SDOCT), for comparison with histology of normal macula; to report thickness and position of bands, particularly band 2 (ellipsoid zone [EZ], commonly called IS/OS). Methods. Foveal and superior perifoveal scans of seven SDOCT volumes of five individuals aged 28 to 69 years with healthy maculas were used (seven eyes for validation, five eyes for measurement). RefMoB determines band thickness and position by a multistage procedure that models reflectivities as a summation of Gaussians. Band thickness and positions were compared with those obtained by manual evaluators for the same scans, and compared with an independent published histological dataset. Results. Agreement among manual evaluators was moderate. Relative to manual evaluation, RefMoB reported reduced thickness and vertical shifts in band positions in a band-specific manner for both simulated and empirical data. In foveal and perifoveal scans, band 1 was thick relative to the anatomical external limiting membrane, band 2 aligned with the outer one-third of the anatomical IS ellipsoid, and band 3 (IZ, interdigitation of retinal pigment epithelium and photoreceptors) was cleanly delineated. Conclusions. RefMoB is suitable for automatic description of the location and thickness of the four outer retinal hyperreflective bands. Initial results suggest that band 2 aligns with the outer ellipsoid, thus supporting its recent designation as EZ. Automated and objective delineation of band 3 will help investigations of structural biomarkers of dark-adaptation changes in aging. PMID:26132776

Contributions from inner and outer shell electron energies to reaction heats for C/sub 1/, C/sub 2/, and C/sub 3/ hydrocarbons

DOE Office of Scientific and Technical Information (OSTI.GOV)

George, P.; Bock, C.W.; Trachtman, M.

1979-04-01

The expectation energy values E/sub k/, V/sub ee/, V/sub nn/, V/sub en/, and E/sub T/ have been calculated for H/sub 2/ and the C/sub 1/, C/sub 2/, and C/sub 3/ hydrocarbons using a (9,5) basis set and the experimental geometries. Treating the theoretical reaction heat, ..delta..E/sub T/, as the resultant of the nuclear repulsion term, ..delta..V/sub nn/, and the net electron energy term, ..delta..E/sub elec/ = ..delta..E/sub k/ + ..delta..V/sub ee/ + ..delta..V/sub en/, the contribution of inner and outer shell electron energies to ..delta..E/sub elec/, and hence to ..delta..E/sub T/, has been calculated for a large number of hydrocarbonmore » reactions by evaluating the Coulson--Neilson energies eta/sub i/, where eta/sub i/ = E/sub elec/. For the vast majority of reactions, 67/84, the change in inner shell electron energy, (..delta sigma..eta/sub i/)/sub inner/, accounts for more than 10% of ..delta..E/sub elec/, in many cases being as high as 20-35%. Furthermore, in addition to these cases in which the change in inner shell electron energy serves to augment (significantly) the change in outer shell electron energy, there are other cases in which the change in inner shell electron energy either exceeds in magnitude the change in outer shell energy, or is even opposite in sign, indicative of inner and outer shell electrons acting contrariwise. Inner shell electron energies contribute to the reaction heats because they are structure dependent, like the more familiar orbital energies epsilon, but the dependence is of a different kind.« less

Comparison of High-Speed Operating Characteristics of Size 215 Cylindrical-Roller Bearings as Determined in Turbojet Engine and in Laboratory Test Rig

NASA Technical Reports Server (NTRS)

Macks, E Fred; Nemeth, Zolton N

1951-01-01

A comparison of the operating characteristics of 75-millimeter-bore (size 215) cylindrical-roller one-piece inner-race-riding cage-type bearings was made using a laboratory test rig and a turbojet engine. Cooling correlation parameters were determined by means of dimensional analysis, and the generalized results for both the inner- and outer-race bearing operating temperatures are compared for the laboratory test rig and the turbojet engine. Inner- and outer-race cooling-correlation curves were obtained for the turbojet-engine turbine-roller bearing with the same inner- and outer-race correlation parameters and exponents as those determined for the laboratory test-rig bearing. The inner- and outer-race turbine roller-bearing temperatures may be predicted from a single curve, regardless of variations in speed, load, oil flow, oil inlet temperature, oil inlet viscosity, oil-jet diameter or any combination of these parameters. The turbojet-engine turbine-roller-bearing inner-race temperatures were 30 to 60 F greater than the outer-race-maximum temperatures, the exact values depending on the operating condition and oil viscosity; these results are in contrast to the laboratory test-rig results where the inner-race temperatures were less than the outer-race-maximum temperatures. The turbojet-engine turbine-roller bearing, maximum outer-race circumferential temperature variation was approximately 30 F for each of the oils used. The effect of oil viscosity on inner- and outer-race turbojet-engine turbine-roller-bearing temperatures was found to be significant. With the lower viscosity oil (6x10(exp -7) reyns (4.9 centistokes) at 100 F; viscosity index, 83), the inner-race temperature was approximately 30 to 35 F less than with the higher viscosity oil (53x10(exp -7) reyns (42.8 centistokes) at 100 F; viscosity index, 150); whereas the outer-race-maximum temperatures were 12 to 28 F lower with the lower viscosity oil over the DN range investigated.

Inner shell radial pin geometry and mounting arrangement

DOEpatents

Leach, David; Bergendahl, Peter Allen

2002-01-01

Circumferentially spaced arrays of support pins are disposed through access openings in an outer turbine shell and have projections received in recesses in forward and aft sections of an inner turbine shell supported from the outer shell. The projections have arcuate sides in a circumferential direction affording line contacts with the side walls of the recesses and are spaced from end faces of the recesses, enabling radial and axial expansion and contraction of the inner shell relative to the outer shell. All loads are taken up in a tangential direction by the outer shell with the support pins taking no radial loadings.

Remote vacuum compaction of compressible hazardous waste

DOEpatents

Coyne, M.J.; Fiscus, G.M.; Sammel, A.G.

1998-10-06

A system is described for remote vacuum compaction and containment of low-level radioactive or hazardous waste comprising a vacuum source, a sealable first flexible container, and a sealable outer flexible container for receiving one or more first flexible containers. A method for compacting low level radioactive or hazardous waste materials at the point of generation comprising the steps of sealing the waste in a first flexible container, sealing one or more first containers within an outer flexible container, breaching the integrity of the first containers, evacuating the air from the inner and outer containers, and sealing the outer container shut. 8 figs.

Remote vacuum compaction of compressible hazardous waste

DOEpatents

Coyne, Martin J.; Fiscus, Gregory M.; Sammel, Alfred G.

1998-01-01

A system for remote vacuum compaction and containment of low-level radioactive or hazardous waste comprising a vacuum source, a sealable first flexible container, and a sealable outer flexible container for receiving one or more first flexible containers. A method for compacting low level radioactive or hazardous waste materials at the point of generation comprising the steps of sealing the waste in a first flexible container, sealing one or more first containers within an outer flexible container, breaching the integrity of the first containers, evacuating the air from the inner and outer containers, and sealing the outer container shut.

Concentric Coplanar Capacitive Sensor System with Quantitative Model

NASA Technical Reports Server (NTRS)

Chen, Tianming (Inventor); Bowler, Nicola (Inventor)

2014-01-01

A concentric coplanar capacitive sensor includes a charged central disc forming a first electrode, an outer annular ring coplanar with and outer to the charged central disc, the outer annular ring forming a second electrode, and a gap between the charged central disc and the outer annular ring. The first electrode and the second electrode may be attached to an insulative film. A method provides for determining transcapacitance between the first electrode and the second electrode and using the transcapacitance in a model that accounts for a dielectric test piece to determine inversely the properties of the dielectric test piece.

Photovoltaic module mounting clip with integral grounding

DOEpatents

Lenox, Carl J.

2008-10-14

An electrically conductive mounting/grounding clip, for use with a photovoltaic assembly of the type having an electrically conductive frame, comprises an electrically conductive body. The body has a central portion and first and second spaced-apart arms extending generally perpendicular to the central portion. Each arm has an outer portion with each outer portion having an outer end. At least one frame surface-disrupting element is at each outer end. The central portion defines a plane with the frame surface-disrupting elements pointing towards the plane. In some examples each arm extends from the central portion at an acute angle to the plane.

Flexure Bearing Reduces Startup Friction

NASA Technical Reports Server (NTRS)

Clingman, W. Dean

1991-01-01

Design concept for ball bearing incorporates small pieces of shim stock, wire spokes like those in bicycle wheels, or other flexing elements to reduce both stiction and friction slope. In flexure bearing, flexing elements placed between outer race of ball bearing and outer ring. Elements flex when ball bearings encounter small frictional-torque "bumps" or even larger ones when bearing balls encounter buildups of grease on inner or outer race. Flexure of elements reduce high friction slopes of "bumps", helping to keep torque between outer ring and inner race low and more nearly constant. Concept intended for bearings in gimbals on laser and/or antenna mirrors.

Remote vacuum compaction of compressible hazardous waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coyne, M.J.; Fiscus, G.M.; Sammel, A.G.

1996-12-31

A system is described for remote vacuum compaction and containment of low-level radioactive or hazardous waste comprising a vacuum source, a sealable first flexible container, and a sealable outer flexible container for receiving one or more first flexible containers. A method for compacting low level radioactive or hazardous waste materials at the point of generation comprising the steps of sealing the waste in a first flexible container, sealing one or more first containers within an outer flexible container, breaching the integrity of the first containers, evacuating the air from the inner and outer containers, and sealing the outer container shut.

Flow and heat transfer in a curved channel

NASA Technical Reports Server (NTRS)

Brinich, P. F.; Graham, R. W.

1977-01-01

Flow and heat transfer in a curved channel of aspect ratio 6 and inner- to outer-wall radius ratio 0.96 were studied. Secondary currents and large longitudinal vortices were found. The heat-transfer rates of the outer and inner walls were independently controlled to maintain a constant wall temperature. Heating the inner wall increased the pressure drop along the channel length, whereas heating the outer wall had little effect. Outer-wall heat transfer was as much as 40 percent greater than the straight-channel correlation, and inner-wall heat transfer was 22 percent greater than the straight-channel correlation.

Radioisotope Reduction Using Solar Power for Outer Planetary Missions

NASA Technical Reports Server (NTRS)

Fincannon, James

2008-01-01

Radioisotope power systems have historically been (and still are) the power system of choice from a mass and size perspective for outer planetary missions. High demand for and limited availability of radioisotope fuel has made it necessary to investigate alternatives to this option. Low mass, high efficiency solar power systems have the potential for use at low outer planetary temperatures and illumination levels. This paper documents the impacts of using solar power systems instead of radioisotope power for all or part of the power needs of outer planetary spacecraft and illustrates the potential fuel savings of such an approach.

Surgical Marking Pen Dye Inhibits Saphenous Vein Cell Proliferation and Migration in Saphenous Vein Graft Tissue

PubMed Central

Kikuchi, Shinsuke; Kenagy, Richard D; Gao, Lu; Wight, Thomas N; Azuma, Nobuyoshi; Sobel, Michael; Clowes, Alexander W

2014-01-01

Objective Markers containing dyes such as crystal violet (CAS 548-62-9) are routinely used on the adventitia of vein bypass grafts to avoid twisting during placement. Since little is known about how these dyes affect vein graft healing and function, we determined the effect of crystal violet on cell migration and proliferation, which are responses to injury after grafting. Methods Fresh human saphenous veins were obtained as residual specimens from leg bypass surgeries. Portions of the vein that had been surgically marked with crystal violet were analyzed separately from those that had no dye marking. In the laboratory, they were split into easily dissected inner and outer layers after removal of endothelium. This f cleavage plane was within the circular muscle layer of the media. Cell migration from explants was measured daily as either 1) % migration positive explants, which exclusively measures migration, or 2) the number of cells on the plastic surrounding each explant, which measures migration plus proliferation. Cell proliferation and apoptosis (Ki67 and TUNEL staining, respectively) were determined in dye-marked and unmarked areas of cultured vein rings. The dose-dependent effects of crystal violet were measured for cell migration from explants as well as proliferation, migration, and death of cultured outer layer cells. Dye was extracted from explants with ethanol and quantified by spectrophotometry. Results There was significantly less cell migration from visibly blue, compared to unstained, outer layer explants by both methods. There was no significant difference in migration from inner layer explants adjacent to blue-stained or unstained sections of vein, because dye did not penetrate to the inner layer. Ki67 staining of vein in organ culture, which is a measure of proliferation, progressively increased up to 6 days in non-blue outer layer and was abolished in the blue outer layer. Evidence of apoptosis (TUNEL staining) was present throughout the wall and not different in blue-stained and unstained vein wall segments. Blue outer layer explants had 65.9±8.0 ng dye/explant compared to 2.1±1.3 for non-blue outer layer explants. Dye applied in vitro to either outer or inner layer explants dose-dependently inhibited migration (IC50=8.5 ng/explant). The IC50s of crystal violet for outer layer cell proliferation and migration were 0.1 and 1.2 μg/ml, while the EC50 for death was between 1 and 10 μg/ml. Conclusion Crystal violet inhibits venous cell migration and proliferation indicating that alternative methods should be considered for marking vein grafts. PMID:25935273

A New Perspective on Galaxy Evolution from the Low Density Outskirts of Galaxies

NASA Astrophysics Data System (ADS)

Emery Watkins, Aaron

2017-01-01

In order to investigate the nature of galaxy outskirts, we carried out a deep imaging campaign of several nearby ($D\\lesssim$10Mpc) galaxies, across a range of environments. We found that most of the galaxies we imaged show red and non-star-forming outer disks, implying evolved stellar populations. Such populations in outer disks are expected as the result of radial migration, yet through Fourier analysis we found no evidence of extended spiral structure in these galaxies. Without star formation or outer spiral structure, it is difficult to determine how these outer disks formed. To investigate the effects of interactions on outer disks, we also observed the Leo I Group; however, while group environments are expected to promote frequent interactions, we found only three extremely faint tidal streams, implying a calm interaction history. As Leo I is fairly low density, this implies that loose groups are ineffective at producing intragroup light (IGL). In the famous interacting system M51, we found that its extended tidal features show similarly red colors as the typical outer disks we observed, implying that M51 had a similar outer disk prior to the interaction, and that the interaction induced no extended star formation, including in the system's HI tail. Therefore, to investigate the nature of star formation in low-density environments, we carried out deep narrow-band H$\\alpha$ imaging of M101 and M51.

Process for off-gas particulate removal and apparatus therefor

DOEpatents

Carl, D.E.

1997-10-21

In the event of a breach in the off-gas line of a melter operation requiring closure of the line, a secondary vessel vent line is provided with a particulate collector utilizing atomization for removal of large particulates from the off-gas. The collector receives the gas containing particulates and directs a portion of the gas through outer and inner annular channels. The collector further receives a fluid, such as water, which is directed through the outer channel together with a second portion of the particulate-laden gas. The outer and inner channels have respective ring-like termination apertures concentrically disposed adjacent one another on the outer edge of the downstream side of the particulate collector. Each of the outer and inner channels curves outwardly away from the collector`s centerline in proceeding toward the downstream side of the collector. Gas flow in the outer channel maintains the fluid on the channel`s wall in the form of a ``wavy film,`` while the gas stream from the inner channel shears the fluid film as it exits the outer channel in reducing the fluid to small droplets. Droplets formed by the collector capture particulates in the gas stream by one of three mechanisms: impaction, interception or Brownian diffusion in removing the particulates. The particulate-laden droplets are removed from the fluid stream by a vessel vent condenser or mist eliminator. 4 figs.

Dissecting Escherichia coli Outer Membrane Biogenesis Using Differential Proteomics

PubMed Central

Martorana, Alessandra M.; Motta, Sara; Di Silvestre, Dario; Falchi, Federica; Dehò, Gianni; Mauri, Pierluigi; Sperandeo, Paola; Polissi, Alessandra

2014-01-01

The cell envelope of Gram-negative bacteria is a complex multi-layered structure comprising an inner cytoplasmic membrane and an additional asymmetric lipid bilayer, the outer membrane, which functions as a selective permeability barrier and is essential for viability. Lipopolysaccharide, an essential glycolipid located in the outer leaflet of the outer membrane, greatly contributes to the peculiar properties exhibited by the outer membrane. This complex molecule is transported to the cell surface by a molecular machine composed of seven essential proteins LptABCDEFG that form a transenvelope complex and function as a single device. While advances in understanding the mechanisms that govern the biogenesis of the cell envelope have been recently made, only few studies are available on how bacterial cells respond to severe envelope biogenesis defects on a global scale. Here we report the use of differential proteomics based on Multidimensional Protein Identification Technology (MudPIT) to investigate how Escherichia coli cells respond to a block of lipopolysaccharide transport to the outer membrane. We analysed the envelope proteome of a lptC conditional mutant grown under permissive and non permissive conditions and identified 123 proteins whose level is modulated upon LptC depletion. Most such proteins belong to pathways implicated in cell envelope biogenesis, peptidoglycan remodelling, cell division and protein folding. Overall these data contribute to our understanding on how E. coli cells respond to LPS transport defects to restore outer membrane functionality. PMID:24967819

Viability of cumulus cells is associated with basal AMH levels in assisted reproduction.

PubMed

Ebner, Thomas; Shebl, Omar; Holzer, Sandra; Oppelt, Peter; Petek, Erwin; Schappacher-Tilp, Gudrun; Mayer, Richard B

2014-12-01

An interesting non-invasive approach to select embryos for transfer is analyzing the health state of somatic granulosa cells surrounding the oocyte addressing their mutual dependence. This prospective study was set up to analyse whether the DNA integrity of cumulus cells correlates with preimplantation development and basal AMH levels. Therefore, 56 patients who gave written consent were enrolled. Sequential denudation of the cumulus-oocyte-complexes was performed in order to separate corona radiata from outer cumulus cells. DNA integrity of both cell types was analysed using a modified chromatin dispersion test. The percentage of viable corona radiata cells per patient showed a linear correlation to blastulation (P<0.05). These innermost cells showed significantly lower rates of strand breaks (P<0.01) as compared to outer cumulus cells. Age-corrected AMH was significantly associated with the DNA integrity of outer cumulus cells (P<0.05). For the first time it could be shown that in fact clinical embryologists deal with two different entities of cumulus cells, inner and outer ones. It seems that any protective mechanism of the female gamete follows an outward gradient, so that negative effects, e.g. apoptosis, may impair outer cumulus cells first. Age-corrected AMH reflects quality of these outer cumulus cells. AMH; Corona radiata cells; DNA fragmentation; Outer cumulus cells; SCD test. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

77 FR 74736 - Petition for Waiver of Compliance

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-17

... deficiency is a technical term describing the imbalance of inner and outer wheel loads when a rail vehicle... rail is elevated above the inner rail), the loads on both inner and outer wheels will be equal, i.e... than the balance speed, the centrifugal force will cause the outer wheel load to increase and the inner...

Assessment of Identity Status in College Women Using Outer Space and Inner Space Interviews.

ERIC Educational Resources Information Center

Hopkins, Linda B.

1982-01-01

Investigated the validity of two approaches to the assessment of female identity status: the standard Outer Space interview used with males, and an Inner Space interview specifically developed for females. Found that, contrary to Erikson's theory, college women form their identities around Outer Space as well as Inner Space issues. (Author/GC)

Design Of Robots For Outer Space

NASA Technical Reports Server (NTRS)

Roston, Gerald P.

1990-01-01

Report discusses design of robots for use in zero gravity and vacuum, with attention to differences between requirements imposed on designs by outer space and by terrestrial applications. Terrestrial robots designed for multiple purposes and for minimal cost. Outer-space robots designed specialized to one task where cost has relatively low priority. Design optimal in one environment unlikely optimal in another.

77 FR 5529 - Commercial Lease of Submerged Lands for Renewable Energy Development on the Outer Continental Shelf

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-03

... Submerged Lands for Renewable Energy Development on the Outer Continental Shelf AGENCY: Bureau of Ocean... use Form 0008 to issue commercial renewable energy leases on the Outer Continental Shelf (OCS). In the preamble to the April 29, 2009, Final Rule, ``Renewable Energy and Alternate Uses of Existing Facilities on...

49 CFR 173.340 - Tear gas devices.

Code of Federal Regulations, 2013 CFR

2013-10-01

... functioning elements must be packed in one box, and the gross weight of the outer box may not exceed 35 kg (77... inner packagings must be packed in one outer box, and the gross weight of the outer box may not exceed... similar devices must be packaged in one of the following packagings conforming to the requirements of part...

49 CFR 173.340 - Tear gas devices.

Code of Federal Regulations, 2014 CFR

2014-10-01

... functioning elements must be packed in one box, and the gross weight of the outer box may not exceed 35 kg (77... inner packagings must be packed in one outer box, and the gross weight of the outer box may not exceed... similar devices must be packaged in one of the following packagings conforming to the requirements of part...

77 FR 71621 - Atlantic Wind One (ATLW1) Commercial Leasing for Wind Power on the Outer Continental Shelf...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-03

... Wind One (ATLW1) Commercial Leasing for Wind Power on the Outer Continental Shelf Offshore Virginia... Notice for Commercial Leasing for Wind Power on the Outer Continental Shelf Offshore Virginia. SUMMARY... (FONSI) for commercial wind lease issuance and site assessment activities on the Atlantic OCS offshore...

77 FR 10707 - Safety Zone; NOBLE DISCOVERER, Outer Continental Shelf Drillship, Chukchi and Beaufort Seas, Alaska

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-23

...-AA00 Safety Zone; NOBLE DISCOVERER, Outer Continental Shelf Drillship, Chukchi and Beaufort Seas... Chukchi and Beaufort Seas Outer Continental Shelf, Alaska, from 12:01 a.m. on July 1, 2012 through 11:59 p... order to drill exploratory wells in several prospects located in the Chukchi and Beaufort Seas during...

Long-Lived Glass Mirrors For Outer Space

NASA Technical Reports Server (NTRS)

Bouquet, Frank L.; Maag, Carl R.; Heggen, Philip M.

1988-01-01

Paper summarizes available knowledge about glass mirrors for use in outer space. Strengths and weaknesses of various types of first and second reflective surfaces identified. Second-surface glass mirrors used in outer space designed to different criteria more stringent for terrestrial mirrors. Protons, electrons, cosmic rays, meteorites, and orbiting space debris affect longevities of components. Contamination also factor in space.

76 FR 20530 - Safety Zone; Boom Days, Buffalo Outer Harbor, Buffalo, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

...[deg]51'47.61'' W (NAD 83). (b) Effective period. This regulation will be effective and the safety zone...-AA00 Safety Zone; Boom Days, Buffalo Outer Harbor, Buffalo, NY AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone in the Buffalo Outer...

Newborns' Face Recognition: Role of Inner and Outer Facial Features

ERIC Educational Resources Information Center

Turati, Chiara; Macchi Cassia, Viola; Simion, Francesca; Leo, Irene

2006-01-01

Existing data indicate that newborns are able to recognize individual faces, but little is known about what perceptual cues drive this ability. The current study showed that either the inner or outer features of the face can act as sufficient cues for newborns' face recognition (Experiment 1), but the outer part of the face enjoys an advantage…

ETR, TRA642. ON GROUND FLOOR. WITH OUTER THERMAL RING IN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ETR, TRA-642. ON GROUND FLOOR. WITH OUTER THERMAL RING IN PLACE AND CONDUIT PRESERVED, HIGH-DENSITY CONCRETE IS PLACED BETWEEN THE THERMAL RING AND THE OUTER REACTOR FORM. INL NEGATIVE NO. 56-2400. Jack L. Anderson, Photographer, 6/10/1956 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

Adsorption mechanisms of selenium oxyanions at the aluminum oxide/water interface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peak, Derek

2008-06-09

Sorption processes at the mineral/water interface typically control the mobility and bioaccessibility of many inorganic contaminants such as oxyanions. Selenium is an important micronutrient for human and animal health, but at elevated concentrations selenium toxicity is a concern. The objective of this study was to determine the bonding mechanisms of selenate (SeO{sub 4}{sup 2-}) and selenite (SeO{sub 3}{sup 2-}) on hydrous aluminum oxide (HAO) over a wide range of reaction pH using extended X-ray absorption fine structure (EXAFS) spectroscopy. Additionally, selenate adsorption on corundum ({alpha}-Al{sub 2}O{sub 3}) was studied to determine if adsorption mechanisms change as the aluminum oxide surfacemore » structure changes. The overall findings were that selenite forms a mixture of outer-sphere and inner-sphere bidentate-binuclear (corner-sharing) surface complexes on HAO, selenate forms primarily outer-sphere surface complexes on HAO, and on corundum selenate forms outer-sphere surface complexes at pH 3.5 but inner-sphere monodentate surface complexes at pH 4.5 and above. It is possible that the lack of inner-sphere complex formation at pH 3.5 is caused by changes in the corundum surface at low pH or secondary precipitate formation. The results are consistent with a structure-based reactivity for metal oxides, wherein hydrous metal oxides form outer-sphere complexes with sulfate and selenate, but inner-sphere monodentate surface complexes are formed between sulfate and selenate and {alpha}-Me{sub 2}O{sub 3}.« less

Continuous Time Random Walk and Migration-Proliferation Dichotomy of Brain Cancer

NASA Astrophysics Data System (ADS)

Iomin, A.

A theory of fractional kinetics of glial cancer cells is presented. A role of the migration-proliferation dichotomy in the fractional cancer cell dynamics in the outer-invasive zone is discussed and explained in the framework of a continuous time random walk. The main suggested model is based on a construction of a 3D comb model, where the migration-proliferation dichotomy becomes naturally apparent and the outer-invasive zone of glioma cancer is considered as a fractal composite with a fractal dimension Dfr < 3.

Superficial Macromolecular Arrays on the Cell Wall of Spirillum putridiconchylium

PubMed Central

Beveridge, T. J.; Murray, R. G. E.

1974-01-01

Electron microscopy of the cell envelope of Spirillum putridiconchylium, using negatively stained, thin-sectioned, and replicated freeze-etched preparations, showed two superficial wall layers forming a complex macromolecular pattern on the external surface. The outer structured layer was a linear array of particles overlying an inner tetragonal array of larger subunits. They were associated in a very regular fashion, and the complex was bonded to the outer, pitted surface of the lipopolysaccharide tripartite layer of the cell wall. The relationship of the components of the two structured layers was resolved with the aid of optical diffraction, combined with image filtering and reconstruction and linear and rotary integration techniques. The outer structural layer consisted of spherical 1.5-nm units set in double lines determined by the size and arrangement of 6- by 3-nm inner structural layer subunits, which bore one outer structural layer unit on each outer corner. The total effect of this arrangement was a double-ridged linear structure that was evident in surface replicas and negatively stained fragments of the whole wall. The packing of these units was not square but skewed by 2° off the perpendicular so that the “unit array” described by optical diffraction and linear integration appeared to be a deformed tetragon. The verity of the model was checked by using a photographically reduced image to produce an optical diffraction pattern for comparison with that of the actual layers. The correspondence was nearly perfect. Images PMID:4137219

Comparing private and public transport access to diabetic health services across inner, middle, and outer suburbs of Melbourne, Australia.

PubMed

Madill, Rebecca; Badland, Hannah; Mavoa, Suzanne; Giles-Corti, Billie

2018-04-13

Melbourne, Australia is experiencing rapid population growth, with much of this occurring in metropolitan outer suburban areas, also known as urban growth areas. Currently little is known about differences in travel times when using private and public transport to access primary and secondary services across Melbourne's urban growth areas. Plan Melbourne Refresh, a recent strategic land use document has called for a 20 min city, which is where essential services including primary health care, can be accessed within a 20 min journey. Type 2 diabetes mellitus (T2DM) is a major chronic condition in Australia, with some of Melbourne's growth areas having some of the highest prevalence across Australia. This study explores travel times to diabetic health care services for populations residing in inner, middle and outer suburbs of metropolitan Melbourne. Geographic information systems (GIS) software were used to map the location of selected diabetic primary and secondary health care service providers across metropolitan inner, middle, outer established, outer urban growth and outer fringe areas of Melbourne. An origin-destination matrix was used to estimate travel distances from point of origin (using a total of approximately 50,000 synthetic residential addresses) to the closest type of each diabetic health care service provider (destinations) across Melbourne. ArcGIS was used to estimate travel times for private transport and public transport; comparisons were made by area. Our study indicated increased travel times to diabetic health services for people living in Melbourne's outer growth and outer fringe areas compared with the rest of Melbourne (inner, middle and outer established). Compared with those living in inner city areas, the median time spent travelling to diabetic services was between 2.46 and 23.24 min (private motor vehicle) and 12.01 and 43.15 min (public transport) longer for those living in outer suburban areas. Irrespective of travel mode used, results indicate that those living in inner and middle suburbs of Melbourne have shorter travel times to access diabetic health services, compared with those living in outer areas of Melbourne. Private motor vehicle travel times were approximately 4 to 5 times faster than public transport modes to access diabetic health services in all areas. Those living in new urban growth communities spend considerably more time travelling to access diabetic health services - particularly specialists - than those living in established areas across Melbourne.

ACUTE ZONAL OCCULT OUTER RETINOPATHY: Structural and Functional Analysis Across the Transition Zone Between Healthy and Diseased Retina.

PubMed

Duncker, Tobias; Lee, Winston; Jiang, Fan; Ramachandran, Rithambara; Hood, Donald C; Tsang, Stephen H; Sparrow, Janet R; Greenstein, Vivienne C

2018-01-01

To assess structure and function across the transition zone (TZ) between relatively healthy and diseased retina in acute zonal occult outer retinopathy. Six patients (6 eyes; age 22-71 years) with acute zonal occult outer retinopathy were studied. Spectral-domain optical coherence tomography, fundus autofluorescence, near-infrared reflectance, color fundus photography, and fundus perimetry were performed and images were registered to each other. The retinal layers of the spectral-domain optical coherence tomography scans were segmented and the thicknesses of two outer retinal layers, that is, the total receptor and outer segment plus layers, and the retinal nerve fiber layer were measured. All eyes showed a TZ on multimodal imaging. On spectral-domain optical coherence tomography, the TZ was in the nasal retina at varying distances from the fovea. For all eyes, it was associated with loss of the ellipsoid zone band, significant thinning of the two outer retinal layers, and in three eyes with thickening of the retinal nerve fiber layer. On fundus autofluorescence, all eyes had a clearly demarcated peripapillary area of abnormal fundus autofluorescence delimited by a border of high autofluorescence; the latter was associated with loss of the ellipsoid zone band and with a change from relatively normal to markedly decreased or nonrecordable visual sensitivity on fundus perimetry. The results of multimodal imaging clarified the TZ in acute zonal occult outer retinopathy. The TZ was outlined by a distinct high autofluorescence border that correlated with loss of the ellipsoid zone band on spectral-domain optical coherence tomography. However, in fundus areas that seemed healthy on fundus autofluorescence, thinning of the outer retinal layers and thickening of the retinal nerve fiber layer were observed near the TZ. The TZ was also characterized by a decrease in visual sensitivity.

Tom7 modulates the dynamics of the mitochondrial outer membrane translocase and plays a pathway-related role in protein import.

PubMed Central

Hönlinger, A; Bömer, U; Alconada, A; Eckerskorn, C; Lottspeich, F; Dietmeier, K; Pfanner, N

1996-01-01

The preprotein translocase of the outer mitochondrial membrane is a multi-subunit complex with receptors and a general import pore. We report the molecular identification of Tom7, a small subunit of the translocase that behaves as an integral membrane protein. The deletion of TOM7 inhibited the mitochondrial import of the outer membrane protein porin, whereas the import of preproteins destined for the mitochondrial interior was impaired only slightly. However, protein import into the mitochondrial interior was strongly inhibited when it occurred in two steps: preprotein accumulation at the outer membrane in the absence of a membrane potential and subsequent further import after the re-establishment of a membrane potential. The delay of protein import into tom7delta mitochondria seemed to occur after the binding of preproteins to the outer membrane receptor sites. A lack of Tom7 stabilized the interaction between the receptors Tom20 and Tom22 and the import pore component Tom40. This indicated that Tom7 exerts a destabilizing effect on part of the outer membrane translocase, whereas Tom6 stabilizes the interaction between the receptors and the import pore. Synthetic growth defects of the double mutants tom7delta tom20delta and tom7delta tom6delta provided genetic evidence for the functional relationship of Tom7 with Tom20 and Tom6. These results suggest that (i) Tom7 plays a role in sorting and accumulation of the preproteins at the outer membrane, and (ii) Tom7 and Tom6 perform complementary functions in modulating the dynamics of the outer membrane translocase. Images PMID:8641278

Design and Operating Characteristics of High-Speed, Small-Bore, Angular-Contact Ball Bearings

NASA Technical Reports Server (NTRS)

Pinel, Stanley I.; Signer, Hans R.; Zaretsky, Erwin V.

1998-01-01

The computer program SHABERTH was used to analyze 35-mm-bore, angular-contact ball bearings designed and manufactured for high-speed turbomachinery applications. Parametric tests of the bearings were conducted on a high-speed, high-temperature bearing tester and were compared with the computer predictions. Four bearing and cage designs were studied. The bearings were lubricated either by jet lubrication or through the split inner ring with and without outer-ring cooling. The predicted bearing life decreased with increasing speed because of increased operating contact stresses caused by changes in contact angle and centrifugal load. For thrust loads only, the difference in calculated life for the 24 deg. and 30 deg. contact-angle bearings was insignificant. However, for combined loading, the 24 deg. contact-angle bearing gave longer life. For split-inner-ring bearings, optimal operating conditions were obtained with a 24 deg. contact angle and an inner-ring, land-guided cage, using outer-ring cooling in conjunction with low lubricant flow rates. Lower temperature and power losses were obtained with a single-outer-ring, land-guided cage for the 24 deg. contact-angle bearing having a relieved inner ring and partially relieved outer ring. Inner-ring temperatures were independent of lubrication mode and cage design. In comparison with measured values, reasonably good engineering correlation was obtained using the computer program SHABERTH for predicted bearing power loss and for inner- and outer-ring temperatures. The Parker formula for XCAV (used in SHABERTH, a measure of oil volume in the bearing cavity) may need to be refined to reflect bearing lubrication mode, cage design, and location of cage-controlling land.

The Xylella fastidiosa PD1063 Protein Is Secreted in Association with Outer Membrane Vesicles

PubMed Central

Pierce, Brittany K.; Voegel, Tanja; Kirkpatrick, Bruce C.

2014-01-01

Xylella fastidiosa is a gram-negative, xylem-limited plant pathogenic bacterium that causes disease in a variety of economically important agricultural crops including Pierce's disease of grapevines. Xylella fastidiosa biofilms formed in the xylem vessels of plants play a key role in early colonization and pathogenicity by providing a protected niche and enhanced cell survival. Here we investigate the role of Xylella fastidiosa PD1063, the predicted ortholog of Xanthomonas oryzae pv. oryzae PXO_03968, which encodes an outer membrane protein. To assess the function of the Xylella fastidiosa ortholog, we created Xylella fastidiosa mutants deleted for PD1063 and then assessed biofilm formation, cell-cell aggregation and cell growth in vitro. We also assessed disease severity and pathogen titers in grapevines mechanically inoculated with the Xylella fastidiosa PD1063 mutant. We found a significant decrease in cell-cell aggregation among PD1063 mutants but no differences in cell growth, biofilm formation, disease severity or titers in planta. Based on the demonstration that Xanthomonas oryzae pv. oryzae PXO_03968 encodes an outer membrane protein, secreted in association with outer membrane vesicles, we predicted that PD1063 would also be secreted in a similar manner. Using anti-PD1063 antibodies, we found PD1063 in the supernatant and secreted in association with outer membrane vesicles. PD1063 purified from the supernatant, outer membrane fractions and outer membrane vesicles was 19.2 kD, corresponding to the predicted size of the processed protein. Our findings suggest Xylella fastidiosa PD1063 is not essential for development of Pierce's disease in Vitis vinifera grapevines although further research is required to determine the function of the PD1063 outer membrane protein in Xylella fastidiosa. PMID:25426629

The Xylella fastidiosa PD1063 protein is secreted in association with outer membrane vesicles.

PubMed

Pierce, Brittany K; Voegel, Tanja; Kirkpatrick, Bruce C

2014-01-01

Xylella fastidiosa is a gram-negative, xylem-limited plant pathogenic bacterium that causes disease in a variety of economically important agricultural crops including Pierce's disease of grapevines. Xylella fastidiosa biofilms formed in the xylem vessels of plants play a key role in early colonization and pathogenicity by providing a protected niche and enhanced cell survival. Here we investigate the role of Xylella fastidiosa PD1063, the predicted ortholog of Xanthomonas oryzae pv. oryzae PXO_03968, which encodes an outer membrane protein. To assess the function of the Xylella fastidiosa ortholog, we created Xylella fastidiosa mutants deleted for PD1063 and then assessed biofilm formation, cell-cell aggregation and cell growth in vitro. We also assessed disease severity and pathogen titers in grapevines mechanically inoculated with the Xylella fastidiosa PD1063 mutant. We found a significant decrease in cell-cell aggregation among PD1063 mutants but no differences in cell growth, biofilm formation, disease severity or titers in planta. Based on the demonstration that Xanthomonas oryzae pv. oryzae PXO_03968 encodes an outer membrane protein, secreted in association with outer membrane vesicles, we predicted that PD1063 would also be secreted in a similar manner. Using anti-PD1063 antibodies, we found PD1063 in the supernatant and secreted in association with outer membrane vesicles. PD1063 purified from the supernatant, outer membrane fractions and outer membrane vesicles was 19.2 kD, corresponding to the predicted size of the processed protein. Our findings suggest Xylella fastidiosa PD1063 is not essential for development of Pierce's disease in Vitis vinifera grapevines although further research is required to determine the function of the PD1063 outer membrane protein in Xylella fastidiosa.

Inner- and outer-wall sorting of double-walled carbon nanotubes

NASA Astrophysics Data System (ADS)

Li, Han; Gordeev, Georgy; Wasserroth, Sören; Chakravadhanula, Venkata Sai Kiran; Neelakandhan, Shyam Kumar Chethala; Hennrich, Frank; Jorio, Ado; Reich, Stephanie; Krupke, Ralph; Flavel, Benjamin Scott

2017-12-01

Double-walled carbon nanotubes (DWCNTs) consist of two coaxially aligned single-walled carbon nanotubes (SWCNTs), and previous sorting methods only achieved outer-wall electronic-type selectivity. Here, a separation technique capable of sorting DWCNTs by semiconducting (S) or metallic (M) inner- and outer-wall electronic type is presented. Electronic coupling between the inner and outer wall is used to alter the surfactant coating around each of the DWCNT types, and aqueous gel permeation is used to separate them. Aqueous methods are used to remove SWCNT species from the raw material and prepare enriched DWCNT fractions. The enriched DWCNT fractions are then transferred into either chlorobenzene or toluene using the copolymer PFO-BPy to yield the four inner@outer combinations of M@M, M@S, S@M and S@S. The high purity of the resulting fractions is verified by absorption measurements, transmission electron microscopy, atomic force microscopy, resonance Raman mapping and high-density field-effect transistor devices.

Serial turbo trellis coded modulation using a serially concatenated coder

NASA Technical Reports Server (NTRS)

Divsalar, Dariush (Inventor); Dolinar, Samuel J. (Inventor); Pollara, Fabrizio (Inventor)

2010-01-01

Serial concatenated trellis coded modulation (SCTCM) includes an outer coder, an interleaver, a recursive inner coder and a mapping element. The outer coder receives data to be coded and produces outer coded data. The interleaver permutes the outer coded data to produce interleaved data. The recursive inner coder codes the interleaved data to produce inner coded data. The mapping element maps the inner coded data to a symbol. The recursive inner coder has a structure which facilitates iterative decoding of the symbols at a decoder system. The recursive inner coder and the mapping element are selected to maximize the effective free Euclidean distance of a trellis coded modulator formed from the recursive inner coder and the mapping element. The decoder system includes a demodulation unit, an inner SISO (soft-input soft-output) decoder, a deinterleaver, an outer SISO decoder, and an interleaver.

Turbine airfoil with dual wall formed from inner and outer layers separated by a compliant structure

DOEpatents

Campbell,; Christian X. , Morrison; Jay, A [Oviedo, FL

2011-12-20

A turbine airfoil usable in a turbine engine with a cooling system and a compliant dual wall configuration configured to enable thermal expansion between inner and outer layers while eliminating stress formation is disclosed. The compliant dual wall configuration may be formed a dual wall formed from inner and outer layers separated by a compliant structure. The compliant structure may be configured such that the outer layer may thermally expand without limitation by the inner layer. The compliant structure may be formed from a plurality of pedestals positioned generally parallel with each other. The pedestals may include a first foot attached to a first end of the pedestal and extending in a first direction aligned with the outer layer, and may include a second foot attached to a second end of the pedestal and extending in a second direction aligned with the inner layer.

Magnetometer instrument team studies for the definition phase of the outer planets grand tour

NASA Technical Reports Server (NTRS)

Coleman, P. J., Jr.

1972-01-01

The objectives of magnetic field investigations on missions to the outer planets were defined as well as an instrumentation system, a program of studies and instrument development tasks was proposed for the mission definition phase of the Outer Planets Grand Tour project. A report on the status of this program is given. Requirements were also established for the spacecraft and the mission which would insure their compatibility with the magnetic field investigation proposed for the outer planets missions and developed figures of merit for encounter trajectories. The spacecraft-instrumentation interface and the on-board data handling system were defined in various reports by the Project Team and in the reports by the Science Steering Group. The defining program for exploring the outer planets within the more restrictive constraints of the Mariner Jupiter-Saturn project included defining a limited magnetic field investigation.

Multilayer Article Characterized by Low Coefficient of Thermal Expansion Outer Layer

NASA Technical Reports Server (NTRS)

Lee, Kang N. (Inventor)

2004-01-01

A multilayer article comprises a substrate comprising a ceramic or a silicon-containing metal alloy. The ceramic is a Si-containing ceramic or an oxide ceramic with or without silicon. An outer layer overlies the substrate and at least one intermediate layer is located between the outer layer and thc substrate. An optional bond layer is disposed between thc 1 least one intermediate layer and thc substrate. The at least one intermediate layer may comprise an optional chemical barrier layer adjacent the outer layer, a mullite-containing layer and an optional chemical barrier layer adjacent to the bond layer or substrate. The outer layer comprises a compound having a low coefficient of thermal expansion selected from one of the following systems: rare earth (RE) silicates; at least one of hafnia and hafnia-containing composite oxides; zirconia-containing composite oxides and combinations thereof.

Method for pressure modulation of turbine sidewall cavities

DOEpatents

Leone, Sal Albert; Book, Matthew David; Banares, Christopher R.

2002-01-01

A method is provided for controlling cooling air flow for pressure modulation of turbine components, such as the turbine outer sidewall cavities. The pressure at which cooling and purge air is supplied to the turbine outer side wall cavities is modulated, based on compressor discharge pressure (Pcd), thereby to generally maintain the back flow margin (BFM) so as to minimize excessive leakage and the consequent performance deterioration. In an exemplary embodiment, the air pressure within the third stage outer side wall cavity and the air pressure within the fourth stage outer side wall cavity are each controlled to a respective value that is a respective prescribed percentage of the concurrent compressor discharge pressure. The prescribed percentage may be determined from a ratio of the respective outer side wall pressure to compressor discharge pressure at Cold Day Turn Down (CDTD) required to provide a prescribed back flow margin.

System for pressure modulation of turbine sidewall cavities

DOEpatents

Leone, Sal Albert; Book, Matthew David; Banares, Christopher R.

2002-01-01

A system and method are provided for controlling cooling air flow for pressure modulation of turbine components, such as the turbine outer sidewall cavities. The pressure at which cooling and purge air is supplied to the turbine outer side wall cavities is modulated, based on compressor discharge pressure (Pcd), thereby to generally maintain the back flow margin (BFM) so as to minimize excessive leakage and the consequent performance deterioration. In an exemplary embodiment, the air pressure within the third stage outer side wall cavity and the air pressure within the fourth stage outer side wall cavity are each controlled to a respective value that is a respective prescribed percentage of the concurrent compressor discharge pressure. The prescribed percentage may be determined from a ratio of the respective outer side wall pressure to compressor discharge pressure at Cold Day Turn Down (CDTD) required to provide a prescribed back flow margin.

Turbine airfoil with laterally extending snubber having internal cooling system

DOEpatents

Scribner, Carmen Andrew; Messmann, Stephen John; Marsh, Jan H.

2016-09-06

A turbine airfoil usable in a turbine engine and having at least one snubber with a snubber cooling system positioned therein and in communication with an airfoil cooling system is disclosed. The snubber may extend from the outer housing of the airfoil toward an adjacent turbine airfoil positioned within a row of airfoils. The snubber cooling system may include an inner cooling channel separated from an outer cooling channel by an inner wall. The inner wall may include a plurality of impingement cooling orifices that direct impingement fluid against an outer wall defining the outer cooling channel. In one embodiment, the cooling fluids may be exhausted from the snubber, and in another embodiment, the cooling fluids may be returned to the airfoil cooling system. Flow guides may be positioned in the outer cooling channel, which may reduce cross-flow by the impingement orifices, thereby increasing effectiveness.

Turbine vane with high temperature capable skins

DOEpatents

Morrison, Jay A [Oviedo, FL

2012-07-10

A turbine vane assembly includes an airfoil extending between an inner shroud and an outer shroud. The airfoil can include a substructure having an outer peripheral surface. At least a portion of the outer peripheral surface is covered by an external skin. The external skin can be made of a high temperature capable material, such as oxide dispersion strengthened alloys, intermetallic alloys, ceramic matrix composites or refractory alloys. The external skin can be formed, and the airfoil can be subsequently bi-cast around or onto the skin. The skin and the substructure can be attached by a plurality of attachment members extending between the skin and the substructure. The skin can be spaced from the outer peripheral surface of the substructure such that a cavity is formed therebetween. Coolant can be supplied to the cavity. Skins can also be applied to the gas path faces of the inner and outer shrouds.

Cooled airfoil in a turbine engine

DOEpatents

Vitt, Paul H; Kemp, David A; Lee, Ching-Pang; Marra, John J

2015-04-21

An airfoil in a gas turbine engine includes an outer wall and an inner wall. The outer wall includes a leading edge, a trailing edge opposed from the leading edge in a chordal direction, a pressure side, and a suction side. The inner wall is coupled to the outer wall at a single chordal location and includes portions spaced from the pressure and suction sides of the outer wall so as to form first and second gaps between the inner wall and the respective pressure and suction sides. The inner wall defines a chamber therein and includes openings that provide fluid communication between the respective gaps and the chamber. The gaps receive cooling fluid that provides cooling to the outer wall as it flows through the gaps. The cooling fluid, after traversing at least substantial portions of the gaps, passes into the chamber through the openings in the inner wall.

Electronic transport properties of inner and outer shells in near ohmic-contacted double-walled carbon nanotube transistors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Yuchun; Zhou, Liyan; Zhao, Shangqian

2014-06-14

We investigate electronic transport properties of field-effect transistors based on double-walled carbon nanotubes, of which inner shells are metallic and outer shells are semiconducting. When both shells are turned on, electron-phonon scattering is found to be the dominant phenomenon. On the other hand, when outer semiconducting shells are turned off, a zero-bias anomaly emerges in the dependence of differential conductance on the bias voltage, which is characterized according to the Tomonaga-Luttinger liquid model describing tunneling into one-dimensional materials. We attribute these behaviors to different contact conditions for outer and inner shells of the double-walled carbon nanotubes. A simple model combiningmore » Luttinger liquid model for inner metallic shells and electron-phonon scattering in outer semiconducting shells is given here to explain our transport data at different temperatures.« less

Inner- and outer-wall sorting of double-walled carbon nanotubes.

PubMed

Li, Han; Gordeev, Georgy; Wasserroth, Sören; Chakravadhanula, Venkata Sai Kiran; Neelakandhan, Shyam Kumar Chethala; Hennrich, Frank; Jorio, Ado; Reich, Stephanie; Krupke, Ralph; Flavel, Benjamin Scott

2017-12-01

Double-walled carbon nanotubes (DWCNTs) consist of two coaxially aligned single-walled carbon nanotubes (SWCNTs), and previous sorting methods only achieved outer-wall electronic-type selectivity. Here, a separation technique capable of sorting DWCNTs by semiconducting (S) or metallic (M) inner- and outer-wall electronic type is presented. Electronic coupling between the inner and outer wall is used to alter the surfactant coating around each of the DWCNT types, and aqueous gel permeation is used to separate them. Aqueous methods are used to remove SWCNT species from the raw material and prepare enriched DWCNT fractions. The enriched DWCNT fractions are then transferred into either chlorobenzene or toluene using the copolymer PFO-BPy to yield the four inner@outer combinations of M@M, M@S, S@M and S@S. The high purity of the resulting fractions is verified by absorption measurements, transmission electron microscopy, atomic force microscopy, resonance Raman mapping and high-density field-effect transistor devices.

Active magnetic bearings used as exciters for rolling element bearing outer race defect diagnosis.

PubMed

Xu, Yuanping; Di, Long; Zhou, Jin; Jin, Chaowu; Guo, Qintao

2016-03-01

The active health monitoring of rotordynamic systems in the presence of bearing outer race defect is considered in this paper. The shaft is assumed to be supported by conventional mechanical bearings and an active magnetic bearing (AMB) is used in the mid of the shaft location as an exciter to apply electromagnetic force to the system. We investigate a nonlinear bearing-pedestal system model with the outer race defect under the electromagnetic force. The nonlinear differential equations are integrated using the fourth-order Runge-Kutta algorithm. The simulation and experimental results show that the characteristic signal of outer race incipient defect is significantly amplified under the electromagnetic force through the AMBs, which is helpful to improve the diagnosis accuracy of rolling element bearing׳s incipient outer race defect. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

Counter-Rotatable Fan Gas Turbine Engine with Axial Flow Positive Displacement Worm Gas Generator

NASA Technical Reports Server (NTRS)

Giffin, Rollin George (Inventor); Murrow, Kurt David (Inventor); Fakunle, Oladapo (Inventor)

2014-01-01

A counter-rotatable fan turbine engine includes a counter-rotatable fan section, a worm gas generator, and a low pressure turbine to power the counter-rotatable fan section. The low pressure turbine maybe counter-rotatable or have a single direction of rotation in which case it powers the counter-rotatable fan section through a gearbox. The gas generator has inner and outer bodies having offset inner and outer axes extending through first, second, and third sections of a core assembly. At least one of the bodies is rotatable about its axis. The inner and outer bodies have intermeshed inner and outer helical blades wound about the inner and outer axes and extending radially outwardly and inwardly respectively. The helical blades have first, second, and third twist slopes in the first, second, and third sections respectively. A combustor section extends through at least a portion of the second section.

Thermoelectric Outer Planets Spacecraft (TOPS)

NASA Technical Reports Server (NTRS)

1973-01-01

The research and advanced development work is reported on a ballistic-mode, outer planet spacecraft using radioisotope thermoelectric generator (RTG) power. The Thermoelectric Outer Planet Spacecraft (TOPS) project was established to provide the advanced systems technology that would allow the realistic estimates of performance, cost, reliability, and scheduling that are required for an actual flight mission. A system design of the complete RTG-powered outer planet spacecraft was made; major technical innovations of certain hardware elements were designed, developed, and tested; and reliability and quality assurance concepts were developed for long-life requirements. At the conclusion of its active phase, the TOPS Project reached its principal objectives: a development and experience base was established for project definition, and for estimating cost, performance, and reliability; an understanding of system and subsystem capabilities for successful outer planets missions was achieved. The system design answered long-life requirements with massive redundancy, controlled by on-board analysis of spacecraft performance data.

Partially segmented deformable mirror

DOEpatents

Bliss, E.S.; Smith, J.R.; Salmon, J.T.; Monjes, J.A.

1991-05-21

A partially segmented deformable mirror is formed with a mirror plate having a smooth and continuous front surface and a plurality of actuators to its back surface. The back surface is divided into triangular areas which are mutually separated by grooves. The grooves are deep enough to make the plate deformable and the actuators for displacing the mirror plate in the direction normal to its surface are inserted in the grooves at the vertices of the triangular areas. Each actuator includes a transducer supported by a receptacle with outer shells having outer surfaces. The vertices have inner walls which are approximately perpendicular to the mirror surface and make planar contacts with the outer surfaces of the outer shells. The adhesive which is used on these contact surfaces tends to contract when it dries but the outer shells can bend and serve to minimize the tendency of the mirror to warp. 5 figures.

Partially segmented deformable mirror

DOEpatents

Bliss, Erlan S.; Smith, James R.; Salmon, J. Thaddeus; Monjes, Julio A.

1991-01-01

A partially segmented deformable mirror is formed with a mirror plate having a smooth and continuous front surface and a plurality of actuators to its back surface. The back surface is divided into triangular areas which are mutually separated by grooves. The grooves are deep enough to make the plate deformable and the actuators for displacing the mirror plate in the direction normal to its surface are inserted in the grooves at the vertices of the triangular areas. Each actuator includes a transducer supported by a receptacle with outer shells having outer surfaces. The vertices have inner walls which are approximately perpendicular to the mirror surface and make planar contacts with the outer surfaces of the outer shells. The adhesive which is used on these contact surfaces tends to contract when it dries but the outer shells can bend and serve to minimize the tendency of the mirror to warp.

Falling Outer Rotation Curves of Star-forming Galaxies at 0.6 ≲ z ≲ 2.6 Probed with KMOS3D and SINS/zC-SINF

NASA Astrophysics Data System (ADS)

Lang, Philipp; Förster Schreiber, Natascha M.; Genzel, Reinhard; Wuyts, Stijn; Wisnioski, Emily; Beifiori, Alessandra; Belli, Sirio; Bender, Ralf; Brammer, Gabe; Burkert, Andreas; Chan, Jeffrey; Davies, Ric; Fossati, Matteo; Galametz, Audrey; Kulkarni, Sandesh K.; Lutz, Dieter; Mendel, J. Trevor; Momcheva, Ivelina G.; Naab, Thorsten; Nelson, Erica J.; Saglia, Roberto P.; Seitz, Stella; Tacchella, Sandro; Tacconi, Linda J.; Tadaki, Ken-ichi; Übler, Hannah; van Dokkum, Pieter G.; Wilman, David J.

2017-05-01

We exploit the deep, resolved, Hα kinematic data from the KMOS3D and SINS/zC-SINF surveys to examine the largely unexplored outer-disk kinematics of star-forming galaxies (SFGs), out to the peak of cosmic star formation. Our sample contains 101 SFGs, representative of the more massive (9.3≲ {log}{M}* /{M}⊙ ≲ 11.5) main sequence population at 0.6 ≤ z ≤ 2.6. Through a novel stacking approach, we are able to constrain a representative rotation curve extending out to ˜4 effective radii. This average rotation curve exhibits a significant drop in rotation velocity beyond the turnover, with a slope of {{Δ }}V/{{Δ }}R=-{0.26}-0.09+0.10 in units of normalized coordinates V/V max and R/R turn. This result confirms that the fall-off seen in some individual galaxies is a common feature of our sample of high-z disks. The outer fall-off strikingly deviates from the flat or mildly rising rotation curves of local spiral galaxies that have similar masses. Through a comparison with models that include baryons and dark matter, we demonstrate that the falling stacked rotation curve is consistent with a high mass fraction of baryons, relative to the total dark matter halo (m d ≳ 0.05), in combination with a sizeable level of pressure support in the outer disk. These findings agree with recent studies demonstrating that high-z star-forming disks are strongly baryon-dominated within the disk scale, and furthermore suggest that pressure gradients caused by large, turbulent gas motions are present even in their outer disks. These results are largely independent of our model assumptions, such as the presence of stellar bulges, the effect of adiabatic contraction, and variations in halo concentration.

Joint segmentation of lumen and outer wall from femoral artery MR images: Towards 3D imaging measurements of peripheral arterial disease.

PubMed

Ukwatta, Eranga; Yuan, Jing; Qiu, Wu; Rajchl, Martin; Chiu, Bernard; Fenster, Aaron

2015-12-01

Three-dimensional (3D) measurements of peripheral arterial disease (PAD) plaque burden extracted from fast black-blood magnetic resonance (MR) images have shown to be more predictive of clinical outcomes than PAD stenosis measurements. To this end, accurate segmentation of the femoral artery lumen and outer wall is required for generating volumetric measurements of PAD plaque burden. Here, we propose a semi-automated algorithm to jointly segment the femoral artery lumen and outer wall surfaces from 3D black-blood MR images, which are reoriented and reconstructed along the medial axis of the femoral artery to obtain improved spatial coherence between slices of the long, thin femoral artery and to reduce computation time. The developed segmentation algorithm enforces two priors in a global optimization manner: the spatial consistency between the adjacent 2D slices and the anatomical region order between the femoral artery lumen and outer wall surfaces. The formulated combinatorial optimization problem for segmentation is solved globally and exactly by means of convex relaxation using a coupled continuous max-flow (CCMF) model, which is a dual formulation to the convex relaxed optimization problem. In addition, the CCMF model directly derives an efficient duality-based algorithm based on the modern multiplier augmented optimization scheme, which has been implemented on a GPU for fast computation. The computed segmentations from the developed algorithm were compared to manual delineations from experts using 20 black-blood MR images. The developed algorithm yielded both high accuracy (Dice similarity coefficients ≥ 87% for both the lumen and outer wall surfaces) and high reproducibility (intra-class correlation coefficient of 0.95 for generating vessel wall area), while outperforming the state-of-the-art method in terms of computational time by a factor of ≈ 20. Copyright © 2015 Elsevier B.V. All rights reserved.

Si-depleted outer core inferred from sound velocity measurements of liquid Fe-Si alloys

NASA Astrophysics Data System (ADS)

Nakajima, Y.; Imada, S.; Hirose, K.; Kuwayama, Y.; Sinmyo, R.; Tateno, S.; Ozawa, H.; Tsutsui, S.; Uchiyama, H.; Baron, A. Q. R.

2016-12-01

Recent core formation models [1,2] suggested that a large amount of Si could have been incorporated into the core forming metals in the early stage of the Earth. These studies gave estimates for the Si content in the core, from 2 to 9 wt.%. In order to constrain the Si content of the outer core, we have determined the sound wave velocity of liquid Fe-Si alloys under high pressures and high temperatures. Starting materials of Fe-Si alloys with 6.5 and 9 wt.% Si were melted in a laser-heated diamond-anvil cell. The longitudinal acoustic phonon excitation of a liquid metal was measured up to 52 GPa and 3200 K by using high resolution inelastic X-ray scattering spectroscopy at beamline BL35XU [3] of the SPring-8 synchrotron facility. Our results show that silicon significantly increases the P-wave velocity of liquid Fe. Seismological observation shows that the P-wave velocity in the outer core is 3-4% faster than in pure iron. Comparing the present results with seismological observations, the silicon content of the outer core should be limited to be <2 wt.%, significantly lower than previous estimates based on the element partitioning between core forming mental and silicate magma ocean during core formation processes. This indicates that the present-day core is depleted in Si relative to the ancient core just after core formation, which agrees with the recent proposal [4] that the Si content in the outer core has been diminished by SiO2 crystallization through the core cooling history. [1] Rubie et al. (2011) Earth Planet. Sci. Lett. 301, 31-42. [2] Siebert et al. (2013) Science 339, 1194-1197. [3] Baron et al. (2000) J. Phys. Chem. Solids 61, 461-465 [4] Hirose et al. (2015) Abstract presented at AGU Fall Meeting 2015.

Outer edges of debris discs. How sharp is sharp?

NASA Astrophysics Data System (ADS)

Thébault, P.; Wu, Y.

2008-04-01

Context: Rings or annulus-like features have been observed in most imaged debris discs. Outside the main ring, while some systems (e.g., β Pictoris and AU Mic) exhibit smooth surface brightness profiles (SB) that fall off roughly as ~r-3.5, others (e.g. HR 4796A and HD 139664) display large drops in luminosity at the ring's outer edge and steeper radial luminosity profiles. Aims: We seek to understand this diversity of outer edge profiles under the “natural” collisional evolution of the system, without invoking external agents such as planets or gas. Methods: We use a multi-annulus statistical code to follow the evolution of a collisional population, ranging in size from dust grains to planetesimals and initially confined within a belt (the “birth ring”). The crucial effect of radiation pressure on the dynamics and spatial distribution of the smallest grains is taken into account. We explore the dependence of the resulting disc surface brightness profile on various parameters. Results: The disc typically evolves toward a “standard” steady state, where the radial surface brightness profile smoothly decreases with radius as r-3.5 outside the birth ring. This confirms and extends the semi-analytical study of Strubbe & Chiang (2006, ApJ, 648, 652) and provides a firm basis for interpreting observed discs. Deviations from this typical profile, in the form of a sharp outer edge and a steeper fall-off, occur for two “extreme” cases: 1) when the birth ring is so massive that it becomes radially optically thick for the smallest grains. However, the required disc mass is probably too high here to be realistic; 2) when the dynamical excitation of the dust-producing planetesimals is so low (< e> and < i> ≤ 0.01) that the smallest grains, which otherwise dominate the optical depth of the system, are preferentially depleted. This low-excitation case, although possibly not generic, cannot be ruled out by observations for most systems, . Conclusions: Our “standard” profile provides a satisfactory explanation for a large group of debris discs that show smooth outer edges and SB ∝ r-3.5. Systems with sharper outer edges, barring other confining agents, could still be explained by “natural” collisional evolution if their dynamical excitation is very low. We show that such a dynamically-cold case provides a satisfactory fit to the specific HR4796A ring.

4D Hybrid Ensemble-Variational Data Assimilation for the NCEP GFS: Outer Loops and Variable Transforms

NASA Astrophysics Data System (ADS)

Kleist, D. T.; Ide, K.; Mahajan, R.; Thomas, C.

2014-12-01

The use of hybrid error covariance models has become quite popular for numerical weather prediction (NWP). One such method for incorporating localized covariances from an ensemble within the variational framework utilizes an augmented control variable (EnVar), and has been implemented in the operational NCEP data assimilation system (GSI). By taking the existing 3D EnVar algorithm in GSI and allowing for four-dimensional ensemble perturbations, coupled with the 4DVAR infrastructure already in place, a 4D EnVar capability has been developed. The 4D EnVar algorithm has a few attractive qualities relative to 4DVAR, including the lack of need for tangent-linear and adjoint model as well as reduced computational cost. Preliminary results using real observations have been encouraging, showing forecast improvements nearly as large as were found in moving from 3DVAR to hybrid 3D EnVar. 4D EnVar is the method of choice for the next generation assimilation system for use with the operational NCEP global model, the global forecast system (GFS). The use of an outer-loop has long been the method of choice for 4DVar data assimilation to help address nonlinearity. An outer loop involves the re-running of the (deterministic) background forecast from the updated initial condition at the beginning of the assimilation window, and proceeding with another inner loop minimization. Within 4D EnVar, a similar procedure can be adopted since the solver evaluates a 4D analysis increment throughout the window, consistent with the valid times of the 4D ensemble perturbations. In this procedure, the ensemble perturbations are kept fixed and centered about the updated background state. This is analogous to the quasi-outer loop idea developed for the EnKF. Here, we present results for both toy model and real NWP systems demonstrating the impact from incorporating outer loops to address nonlinearity within the 4D EnVar context. The appropriate amplitudes for observation and background error covariances in subsequent outer loops will be explored. Lastly, variable transformations on the ensemble perturbations will be utilized to help address issues of non-Gaussianity. This may be particularly important for variables that clearly have non-Gaussian error characteristics such as water vapor and cloud condensate.

Spatiotemporal definition of neurite outgrowth, refinement and retraction in the developing mouse cochlea.

PubMed

Huang, Lin-Chien; Thorne, Peter R; Housley, Gary D; Montgomery, Johanna M

2007-08-01

The adult mammalian cochlea receives dual afferent innervation: the inner sensory hair cells are innervated exclusively by type I spiral ganglion neurons (SGN), whereas the sensory outer hair cells are innervated by type II SGN. We have characterized the spatiotemporal reorganization of the dual afferent innervation pattern as it is established in the developing mouse cochlea. This reorganization occurs during the first postnatal week just before the onset of hearing. Our data reveal three distinct phases in the development of the afferent innervation of the organ of Corti: (1) neurite growth and extension of both classes of afferents to all hair cells (E18-P0); (2) neurite refinement, with formation of the outer spiral bundles innervating outer hair cells (P0-P3); (3) neurite retraction and synaptic pruning to eliminate type I SGN innervation of outer hair cells, while retaining their innervation of inner hair cells (P3-P6). The characterization of this developmental innervation pattern was made possible by the finding that tetramethylrhodamine-conjugated dextran (TMRD) specifically labeled type I SGN. Peripherin and choline-acetyltransferase immunofluorescence confirmed the type II and efferent innervation patterns, respectively, and verified the specificity of the type I SGN neurites labeled by TMRD. These findings define the precise spatiotemporal neurite reorganization of the two afferent nerve fiber populations in the cochlea, which is crucial for auditory neurotransmission. This reorganization also establishes the cochlea as a model system for studying CNS synapse development, plasticity and elimination.

Vessel density, retinal thickness, and choriocapillaris vascular flow in myopic eyes on OCT angiography.

PubMed

Milani, Paolo; Montesano, Giovanni; Rossetti, Luca; Bergamini, Fulvio; Pece, Alfredo

2018-06-06

To investigate foveal avascular zone area, macular vascular density, choroidal thickness, and outer retina and choriocapillaris flow in myopic eyes by OCT angiography. Automated macular maps and flow calculations were retrospectively evaluated in 42 myopic and in 40 control eyes. Myopic eyes presented lower whole superficial vessel density (46.4 ± 4.9 vs. 51.6 ± 3.6%, P < 0.0001) and higher flow area in the outer retina (1.3 ± 0.2 vs. 1.1 ± 0.3 mm 2 , P = 0.0012). Between the myopic and non-myopic eyes, no significant differences could be detected in the choriocapillaris perfusion area (1.9 ± 0.07 vs. 1.9 ± 0.05 mm 2 , respectively; P = 0.55) and in the foveal avascular zone area (0.23 ± 0.1 vs. 0.26 ± 0.1 mm 2 , respectively; P = 0.12). The spherical correction positively correlated with superficial vessel density and negatively correlated with outer retina perfusion (P ≤ 0.0021). The superficial vessel density and the local retinal thickness positively correlated at all macular locations (P < 0.005), especially in the foveal region (P < 0.0001). Eyes with high myopia present reduced superficial vascular density and increased outer retina flow. Superficial vascular density and retinal thickness appear to be significantly correlated.

Description of a new species of Microhyla from Bali, Indonesia (Amphibia, Anura).

PubMed

Matsui, Masafumi; Hamidy, Amir; Eto, Koshiro

2013-01-01

We describe a microhylid frog from Bali, Indonesia as a new species, Microhyla orientalis sp. nov. It belongs to the M. achatina group and is close to M. mantheyi, M. malang, and M. borneensis. It is distinguished from its congeners by a combination of the following characters: small size (adult males about 16-17 mm in SVL); a faint vertebral stripe present; a black lateral stripe from behind eye to half length of trunk; snout rounded in profile; eyelid without supraciliary spines; first finger less than one-fifth of third; tips of three outer fingers weakly dilated, forming weak disks, dorsally with median longitudinal groove; outer palmar tubercle single; tibiotarsal articulation reaching up to center of eye; tips of toes distinctly dilated into disks, dorsally with median longitudinal groove; inner and outer metatarsal tubercles present; four or more phalanges on inner and outer sides of fourth toe, and three phalanges on inner side of fifth toe free of web; and tail of larva with a black marking at middle. The male advertisement call of the new species consists of a series of notes each lasts for 0.01-0.08 s and composed of 3-5 pulses with a dominant frequency of 3.2-3.6 kHz. Uncorrected sequence divergences between M. orientalis and all homologous 16S rRNA sequences available were > 6.6%. At present, the new species is known from rice fields between 435-815 m elevation in Wongaya Gede and Batukaru.

Marginally outer trapped surfaces and symmetries

NASA Astrophysics Data System (ADS)

Carrasco, Alberto; Mars, Marc

2009-05-01

We study properties of outermost marginally outer trapped surfaces in slices of space-times possessing certain symmetries, like isometries, homotheties or conformal Killings. In particular, we find restrictions on these surfaces for the vector field generating the symmetry. As an application we give a result of non-existence of outermost marginally outer trapped surfaces in accelerated Friedmann-Lemaître-Roberson-Walker spacetimes.

78 FR 47748 - Right-of-Way Grant of Submerged Lands on the Outer Continental Shelf to Support Renewable Energy...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-06

...-Way Grant of Submerged Lands on the Outer Continental Shelf to Support Renewable Energy Development... will use Form 0009 to issue a renewable energy right-of- way (ROW) grant on the Outer Continental Shelf....gov/Renewable-Energy Program/ Regulatory-Information/Index.aspx. DATES: The ROW grant form will be...

77 FR 52353 - Right-of-Way Grant of Submerged Lands on the Outer Continental Shelf to Support Renewable Energy...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-29

... of Submerged Lands on the Outer Continental Shelf to Support Renewable Energy Development AGENCY... would be used to issue Outer Continental Shelf (OCS) renewable energy right-of-way (ROW) grants in order... renewable energy, but does not constitute a project easement. The ability of an ROW grantee to install such...

Maximum outer-bank velocity reduction for vane-dike fields installed in channel bends

Treesearch

S. Michael Scurlock; Amanda L. Cox; Christopher I. Thornton; Drew C. Baird

2011-01-01

Hydraulic conditions associated with channel bends in meandering rivers include secondary, helical currents, mass shift of flow to the outside of the bend, and increased erosion along the outer streambank. Such outer-bank erosion may result in undesired plan-form migration of the stream course, placing valuable land holdings or infrastructure in jeopardy. A type of in-...

78 FR 52239 - Oil and Gas and Sulphur Operations on the Outer Continental Shelf-Oil and Gas Production Safety...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

... Environmental Enforcement 30 CFR Part 250 Oil and Gas and Sulphur Operations on the Outer Continental Shelf--Oil and Gas Production Safety Systems; Proposed Rule #0;#0;Federal Register / Vol. 78 , No. 163 / Thursday...] RIN 1014-AA10 Oil and Gas and Sulphur Operations on the Outer Continental Shelf--Oil and Gas...

Longleaf pine inner bark and outer bark thicknesses: Measurement and relevance

Treesearch

Thomas Eberhardt

2013-01-01

Measurements of bark thickness generally ignore the fact that bark is comprised of both living inner bark (phloem) and essentially dead outer bark (rhytidome).Discerning between them has ramifications for the utility of bark as a byproduct of timber harvesting and its functionality on a living tree. Inner bark and outer bark thicknesses for longleaf pine (Pinus...

Laminated electromagnetic pump stator core

DOEpatents

Fanning, Alan W.

1995-01-01

A stator core for an electromagnetic pump includes a plurality of circumferentially abutting tapered laminations extending radially outwardly from a centerline axis to collectively define a radially inner bore and a radially outer circumference. Each of the laminations includes radially inner and outer edges and has a thickness increasing from the inner edge toward the outer edge to provide a substantially continuous path adjacent the circumference.

Array of titanium dioxide nanostructures for solar energy utilization

DOEpatents

Qiu, Xiaofeng; Parans Paranthaman, Mariappan; Chi, Miaofang; Ivanov, Ilia N; Zhang, Zhenyu

2014-12-30

An array of titanium dioxide nanostructures for solar energy utilization includes a plurality of nanotubes, each nanotube including an outer layer coaxial with an inner layer, where the inner layer comprises p-type titanium dioxide and the outer layer comprises n-type titanium dioxide. An interface between the inner layer and the outer layer defines a p-n junction.

77 FR 39164 - Safety Zone; KULLUK, Outer Continental Shelf Mobile Offshore Drilling Unit (MODU), Beaufort Sea, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-02

... sensitivity of the environmental and subsistence importance to the indigenous population; (4) the lack of any... Outer Continental Shelf Lands Act and 33 C.F.R 147. Accordingly, State and Local law enforcement... due to the location of the MODU KULLUK on the Outer Continental Shelf and its distance from both land...

Grand Tour outer planet missions definition phase. Part 1: Quantitative imaging of the outer planets and their satellites

NASA Technical Reports Server (NTRS)

Belton, M. J. S.; Aksnes, K.; Davies, M. E.; Hartmann, W. K.; Millis, R. L.; Owen, T. C.; Reilly, T. H.; Sagan, C.; Suomi, V. E.; Collins, S. A., Jr.

1972-01-01

A recommended imaging system is outlined for use aboard the Outer Planet Grand Tour Explorer. The system features the high angular resolution capacity necessary to accommodate large encounter distances, and to satisfy the demand for a reasonable amount of time coverage. Specifications for all components within the system are provided in detail.

SU-F-T-08: Brachytherapy Film Dosimetry in a Water Phantom for a Ring and Tandem HDR Applicator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, B; Grelewicz, Z; Kang, Z

2016-06-15

Purpose: The feasibility of dose measurement using new generation EBT3 film was explored in a water phantom for a ring and tandem HDR applicator for measurements tracking mucosal dose during cervical brachytherapy. Methods: An experimental fixture was assembled to position the applicator in a water phantom. Prior to measurement, calibration curves for EBT3 film in water and in solidwater were verified. EBT3 film was placed at different known locations around the applicator in the water tank. A CT scan of the phantom with applicator was performed using clinical protocol. A typical cervical cancer treatment plan was then generated by Oncentramore » brachytherapy planning system. A dose of 500 cGy was prescribed to point A (2 cm, 2 cm). Locations measured by film included the outer surface of the ring, measurement point A-m (2.2 cm, 2.2 cm), and profiles extending from point A-m parallel to the tandem. Three independent measurements were conducted. The doses recorded by film were carefully analyzed and compared with values calculated by the treatment planning system. Results: Assessment of the EBT3 films indicate that the dose at point A matches the values predicted by the planning system. Dose to the point A-m was 411.5 cGy, and the outer circumferential surface dose of the ring was between 500 and 1150 cGy. It was found that from the point A-m, the dose drops 60% within 4.5 cm on the line parallel to the tandem. The measurement doses agree with the treatment planning system. Conclusion: Use of EBT3 film is feasible for in-water measurements for brachytherapy. A carefully machined apparatus will likely improve measurement accuracy. In a typical plan, our study found that the ring surface dose can be 2.5 times larger than the point A prescription dose. EBT3 film can be used to monitor mucosal dose in brachytherapy treatments.« less

Study of the effects of the outer space environment on dormant forms of microorganisms, fungi and plants in the `Expose-R' experiment

NASA Astrophysics Data System (ADS)

Novikova, N.; Deshevaya, E.; Levinskikh, M.; Polikarpov, N.; Poddubko, S.; Gusev, O.

2015-01-01

Investigations of the effects of solar radiation combined with the spaceflight factors on biological objects were performed in the «EXPOSE-R» experiment on the outer surface of ISS. After more than 1 year of outer space exposure, the spores of microorganisms and fungi, as well as two species of plant seeds were analysed for viability and the set of biological properties. The experiment provided evidence that not only bacterial and fungal spores but also dormant forms of plants had the capability to survive a long-term exposure to outer space.

RADIO FREQUENCY ATTENUATOR

DOEpatents

Giordano, S.

1963-11-12

A high peak power level r-f attenuator that is readily and easily insertable along a coaxial cable having an inner conductor and an outer annular conductor without breaking the ends thereof is presented. Spaced first and second flares in the outer conductor face each other with a slidable cylindrical outer conductor portion therebetween. Dielectric means, such as water, contact the cable between the flares to attenuate the radio-frequency energy received thereby. The cylindrical outer conductor portion is slidable to adjust the voltage standing wave ratio to a low level, and one of the flares is slidable to adjust the attenuation level. An integral dielectric container is also provided. (AFC)

Method and system for control of upstream flowfields of vehicle in supersonic or hypersonic atmospheric flight

NASA Technical Reports Server (NTRS)

Daso, Endwell O. (Inventor); Pritchett, II, Victor E. (Inventor); Wang, Ten-See (Inventor); Farr, Rebecca Ann (Inventor)

2012-01-01

The upstream flowfield of a vehicle traveling in supersonic or hypersonic atmospheric flight is actively controlled using attribute(s) experienced by the vehicle. Sensed attribute(s) include pressure along the vehicle's outer mold line, temperature along the vehicle's outer mold line, heat flux along the vehicle's outer mold line, and/or local acceleration response of the vehicle. A non-heated, non-plasma-producing gas is injected into an upstream flowfield of the vehicle from at least one surface location along the vehicle's outer mold line. The pressure of the gas so-injected is adjusted based on the attribute(s) so-sensed.

NEUTRON COUNTER

DOEpatents

Curtis, C.D.; Carlson, R.L.; Tubinis, M.P.

1958-07-29

An ionization chamber instrument is described for cylindrical electrodes with an ionizing gag filling the channber. The inner electrode is held in place by a hermetic insulating seal at one end of the outer electrode, the other end of the outer electrode being closed by a gas filling tube. The outer surface of the inner electrode is coated with an active material which is responsive to neutron bombardment, such as uranium235 or boron-10, to produce ionizing radiations in the gas. The transverse cross sectional area of the inner electrode is small in relation to that of the channber whereby substantially all of the radiations are directed toward the outer electrode.

Spectral domain optical coherence tomography imaging in optic disk pit associated with outer retinal dehiscence

PubMed Central

Wong, Chee Wai; Wong, Doric; Mathur, Ranjana

2014-01-01

A 37-year-old Bangladeshi male presented with an inferotemporal optic disk pit and serous macular detachment in the left eye. Imaging with spectral domain optical coherence tomography (OCT) revealed a multilayer macular schisis pattern with a small subfoveal outer retinal dehiscence. This case illustrates a rare phenotype of optic disk maculopathy with macular schisis and a small outer retinal layer dehiscence. Spectral domain OCT was a useful adjunct in delineating the retinal layers in optic disk pit maculopathy, and revealed a small area of outer retinal layer dehiscence that could only have been detected on high-resolution OCT. PMID:25349471

Non-binding conductor load bearing roller for a gas-insulated transmission line having a corrugated outer conductor

DOEpatents

Fischer, William H.

1984-01-01

A gas-insulated transmission line includes a corrugated outer conductor, an inner conductor disposed within and insulated from the outer conductor by means of support insulators and an insulating gas, and a non-binding transport device for supporting and permitting movement of the inner conductor/insulating support assembly axially along the corrugated outer conductor without radial displacement and for moving without binding along corrugations of any slope less than vertical. The transport device includes two movable contacts, such as skids or rollers, supported on a common pivot lever, the pivot lever being rotatably disposed about a pivot lever axis, which pivot lever axis is in turn disposed on the periphery of a support insulator or particle trap if one is used. The movable contacts are separated axially a distance equal to the axial distance between the peaks and valleys of the corrugations of the outer conductor and separated radially a distance equal to the radial distance between the peaks and valleys of the corrugations of the outer conductor. The transport device has the pivot lever axis disposed parallel to the motion of travel of the inner conductor/insulating support assembly.

Improved Quick-Release Pin Mechanism

NASA Technical Reports Server (NTRS)

Wright, Jay M.

2007-01-01

An improved quick-release pin mechanism supplants a prior such mechanism in which the pin bears a shear load to hold two objects together. The prior mechanism, of a ball-locking design, can fail when vibrations cause balls to fall out. The load-bearing pin is an outer tube with a handle at one end (hereafter denoted the near end). Within the outer tube is a spring-loaded inner tube that includes a handle at its near end and a pivoting tab at its far end. The pin is inserted through holes in the objects to be retained and the inner tube is pushed against an offset pivot inside the outer tube to make the tab rotate outward so that it protrudes past the outer diameter of the outer tube, and the spring load maintains this configuration so that the pin cannot be withdrawn through the holes. Pushing the handles together against the spring load moves the locking tab out far enough that the tab becomes free to rotate inward. Then releasing the inner-tube handle causes the tab to be pulled into a resting position inside the outer tube. The pin can then be pulled out through the holes.

Developmental patterning of sub-epidermal cells in the outer integument of Arabidopsis seeds

PubMed Central

Fiume, Elisa; Coen, Olivier; Xu, Wenjia; Lepiniec, Loïc

2017-01-01

The seed, the reproductive unit of angiosperms, is generally protected by the seed coat. The seed coat is made of one or two integuments, each comprising two epidermal cells layers and, in some cases, extra sub-epidermal cell layers. The thickness of the seed-coat affects several aspects of seed biology such as dormancy, germination and mortality. In Arabidopsis, the inner integument displays one or two sub-epidermal cell layers that originate from periclinal cell divisions of the innermost epidermal cell layer. By contrast, the outer integument was considered to be two-cell layered. Here, we show that sub-epidermal chalazal cells grow in between the epidermal outer integument cell layers to create an incomplete three-cell layered outer integument. We found that the MADS box transcription factor TRANSPARENT TESTA 16 represses growth of the chalaza and formation of sub-epidermal outer integument cells. Finally, we demonstrate that sub-epidermal cells of the outer and inner integument respond differently to the repressive mechanism mediated by FERTILIZATION INDEPENDENT SEED Polycomb group proteins and to fertilization signals. Our data suggest that integument cell origin rather than sub-epidermal cell position underlies different responses to fertilization. PMID:29141031

Resurrecting Inactive Antimicrobial Peptides from the Lipopolysaccharide Trap

PubMed Central

Mohanram, Harini

2014-01-01

Host defense antimicrobial peptides (AMPs) are a promising source of antibiotics for the treatment of multiple-drug-resistant pathogens. Lipopolysaccharide (LPS), the major component of the outer leaflet of the outer membrane of Gram-negative bacteria, functions as a permeability barrier against a variety of molecules, including AMPs. Further, LPS or endotoxin is the causative agent of sepsis killing 100,000 people per year in the United States alone. LPS can restrict the activity of AMPs inducing aggregations at the outer membrane, as observed for frog AMPs, temporins, and also in model AMPs. Aggregated AMPs, “trapped” by the outer membrane, are unable to traverse the cell wall, causing their inactivation. In this work, we show that these inactive AMPs can overcome LPS-induced aggregations while conjugated with a short LPS binding β-boomerang peptide motif and become highly bactericidal. The generated hybrid peptides exhibit activity against Gram-negative and Gram-positive bacteria in high-salt conditions and detoxify endotoxin. Structural and biophysical studies establish the mechanism of action of these peptides in LPS outer membrane. Most importantly, this study provides a new concept for the development of a potent broad-spectrum antibiotic with efficient outer membrane disruption as the mode of action. PMID:24419338

Apparatus for integrating a rigid structure into a flexible wall of an inflatable structure

NASA Technical Reports Server (NTRS)

Johnson, Christopher J. (Inventor); Patterson, Ross M. (Inventor); Spexarth, Gary R. (Inventor)

2009-01-01

For an inflatable structure having a flexible outer shell or wall structure having a flexible restraint layer comprising interwoven, load-bearing straps, apparatus for integrating one or more substantially rigid members into the flexible shell. For each rigid member, a corresponding opening is formed through the flexible shell for receiving the rigid member. A plurality of connection devices are mounted on the rigid member for receiving respective ones of the load-bearing straps. In one embodiment, the connection devices comprise inner connecting mechanisms and outer connecting mechanisms, the inner and outer connecting mechanisms being mounted on the substantially rigid structure and spaced along a peripheral edge portion of the structure in an interleafed array in which respective outer connecting mechanisms are interposed between adjacent pairs of inner connecting mechanisms, the outer connecting mechanisms projecting outwardly from the peripheral edge portion of the substantially rigid structure beyond the adjacent inner connecting mechanisms to form a staggered array of connecting mechanisms extending along the panel structure edge portion. In one embodiment, the inner and outer connecting mechanisms form part of an integrated, structure rotatably mounted on the rigid member peripheral edge portion.

Extra-mitochondrial aerobic metabolism in retinal rod outer segments: new perspectives in retinopathies.

PubMed

Panfoli, I; Calzia, D; Ravera, S; Morelli, A M; Traverso, C E

2012-04-01

Vertebrate retinal rods are photoreceptors for dim-light vision. They display extreme sensitivity to light thanks to a specialized subcellular organelle, the rod outer segment. This is filled with a stack of membranous disks, expressing the proteins involved in visual transduction, a very energy demanding process. Our previous proteomic and biochemical studies have shed new light on the chemical energy processes that supply ATP to the outer segment, suggesting the presence of an extra-mitochondrial aerobic metabolism in rod outer segment, devoid of mitochondria, which would account for a quantitatively adequate ATP supply for phototransduction. Here the functional presence of an oxidative phosphorylation in the rod outer limb is examined for its relationship to many physiological and pathological data on the rod outer segment. We hypothesize that the rod outer limb is at risk of oxidative stress, in any case of impairment in the respiratory chain functioning, or of blood supply. In fact, the electron transfer chain is a major source of reactive O(2) species, known to produce severe alteration to the membrane lipids, especially those of the outer segment that are rich in polyunsaturated fatty acids. We propose that the disk membrane may become the target of reactive oxygen species that may be released by the electron transport chain under pathologic conditions. For example, during aging reactive oxygen species production increases, while cellular antioxidant capacity decreases. Also the apoptosis of the rod observed after exposure to bright or continuous illumination can be explained considering that an overfunctioning of phototransduction may damage the disk membrane to a point at which cytochrome c escapes from the intradiskal space, where it is presently supposed to be, activating a putative caspase 9 and the apoptosome. A pathogenic mechanism for many inherited and acquired retinal degenerations, representing a major problem in clinical ophthalmology, is proposed: a number of rod pathologies would be promoted by impairment of energy supply and/or oxidative stress in the rod outer segment. In conclusion we suppose that the damaging role of oxygen, be it hypoxia or hyperoxia invoked in most of the blinding diseases, acquired and even hereditary is to be seeked for inside the photoreceptor outer segment that would conceal a potential for cell death that is still to be recognized. Copyright © 2012 Elsevier Ltd. All rights reserved.

Analysis of radiative and phase-change phenomena with application to space-based thermal energy storage

NASA Technical Reports Server (NTRS)

Lund, Kurt O.

1991-01-01

The simplified geometry for the analysis is an infinite, axis symmetric annulus with a specified solar flux at the outer radius. The inner radius is either adiabatic (modeling Flight Experiment conditions), or convective (modeling Solar Dynamic conditions). Liquid LiF either contacts the outer wall (modeling ground based testing), or faces a void gap at the outer wall (modeling possible space based conditions). The analysis is presented in three parts: Part 3 considers and adiabatic inner wall and linearized radiation equations; part 2 adds effects of convection at the inner wall; and part 1 includes the effect of the void gap, as well as previous effects, and develops the radiation model further. The main results are the differences in melting behavior which can occur between ground based 1 g experiments and the microgravity flight experiments. Under 1 gravity, melted PCM will always contact the outer wall having the heat flux source, thus providing conductance from this source to the phase change front. In space based tests where a void gap may likely form during solidification, the situation is reversed; radiation is now the only mode of heat transfer and the majority of melting takes place from the inner wall.

Phase-encoded single-voxel magnetic resonance spectroscopy for suppressing outer volume signals at 7 Tesla.

PubMed

Li, Ningzhi; An, Li; Johnson, Christopher; Shen, Jun

2017-01-01

Due to imperfect slice profiles, unwanted signals from outside the selected voxel may significantly contaminate metabolite signals acquired using in vivo magnetic resonance spectroscopy (MRS). The use of outer volume suppression may exceed the SAR threshold, especially at high field. We propose using phase-encoding gradients after radiofrequency (RF) excitation to spatially encode unwanted signals originating from outside of the selected single voxel. Phase-encoding gradients were added to a standard single voxel point-resolved spectroscopy (PRESS) sequence which selects a 2 × 2 × 2 cm 3 voxel. Subsequent spatial Fourier transform was used to encode outer volume signals. Phantom and in vivo experiments were performed using both phase-encoded PRESS and standard PRESS at 7 Tesla. Quantification was performed using fitting software developed in-house. Both phantom and in vivo studies showed that spectra from the phase-encoded PRESS sequence were relatively immune from contamination by oil signals and have more accurate quantification results than spectra from standard PRESS spectra of the same voxel. The proposed phase-encoded single-voxel PRESS method can significantly suppress outer volume signals that may appear in the spectra of standard PRESS without increasing RF power deposition.

Exploring the Milky Way Disk Abundance Transition Zone Rgc 10 kpc with Open Clusters

NASA Astrophysics Data System (ADS)

Jacobson, Heather R.; Friel, E.; Pilachowski, C.

2009-01-01

Recent studies of the radial chemical abundance distribution among stellar populations in the Galactic disk have shown a change in the abundance trend at galactocentric distance Rgc 10 kpc, as first noted by Twarog et al. (1997). Here the gradient in [Fe/H] with distance appears to vanish, with abundances of stars at greater distances dropping to [Fe/H] -0.3, independent of galactocentric distance. Much is still unknown about the exact nature of the transition from inner to outer disk, and it is still uncertain if the outer disk has had a distinct evolutionary history from that of the inner disk. While current chemical evolution models can well match the outer disk abundances (Cescutti et al. 2007), abundances of many more stars at Rgc 9-12 kpc must be determined to better characterize the nature of the transition from inner to outer disk. We have initiated a survey of abundances of 20 open clusters in this region using spectroscopy obtained with the WIYN, KPNO 4m, CTIO 4m and Hobby-Eberly telescopes. Chemical abundances are determined for Fe, O, Na, and alpha-elements, among others. Results for the survey to date are presented here.

ORBITS OF FOUR YOUNG TRIPLE-LINED MULTIPLE SYSTEMS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tokovinin, Andrei, E-mail: atokovinin@ctio.noao.edu

2016-07-01

Each of the nearby triple systems HIP 7601, 13498, 23824, and 113597 (HD 10800, 18198, 35877, 217379) consist of solar-type dwarfs with comparable masses, where all three components are resolved spectrally, while the outer pairs are resolved both visually and spectrally. These stars are relatively young (between 100 and 600 Myr) and chromospherically active (X-ray sources), although they rotate slowly. I determine the spectroscopic orbits of the inner subsystems (periods 19.4, 14.1, 5.6, 20.3 days) and the orbits of the outer systems (periods 1.75, 51, 27, 500 years, respectively). For HIP 7601 and 13498, the combined spectro-interferometric outer orbits producemore » direct measurement of the masses of all of the components, allowing for a comparison with stellar models. The 6708 Å lithium line is present and its strength is measured in each component individually by subtracting the contributions of the other components. The inner and outer orbits of HIP 7601 are nearly circular, likely co-planar, and have a modest period ratio of 1:33. This study contributes to the characterization of hierarchical multiplicity in the solar neighborhood and provides data for testing stellar evolutionary models and chronology.« less

Detection of MgCn in IRC + 10216: A new metal-bearing free radical

NASA Technical Reports Server (NTRS)

Ziurys, L. M.; Apponi, A. J.; Guelin, M.; Cernicharo, J.

1995-01-01

A new metal-containing molecule, MgCN, has been detected toward the late-type star IRC + 10216, using the NRAO 12 m and IRAM 30 m telescopes. The N = 11 approaches 10, 10 approaches 9, and 9 approaches 8 transtions of this species which has a (sup 2)Sigma(sup +) ground state, have been observed in the outer envelope of this object at 3 mm. For the N = 11 approaches 10 transitions, the two spin-rotation components are clearly resolved and conclusively identify this new radical. These measurements imply a column of density for MgCN of N(sub tot) approximately 10(exp 12)/sq cm in the outer shell, which corresponds to a fractional abundance of f approximately 7x10(exp -10). This molecule, the metastable isomer of MgNC, is the third metal-bearing species thus far identified in the outer shell of IRC + 10216, and its detection implies a ratio of MgNC/MgCN approximately 22/1. MgCN may be formed through a reaction scheme involving magnesium and HNC or CN, both prominent outer shell molecules, or through synthesis on grains.

Gunshot residue patterns on skin in angled contact and near contact gunshot wounds.

PubMed

Plattner, T; Kneubuehl, B; Thali, M; Zollinger, U

2003-12-17

The goal of this study was the reproduction of shape and pattern of gunshot residues in near contact and contact gunshot wounds by a series of experimental gunshots on a skin and soft tissue model. The aim was to investigate the shape and direction of soot deposits with regard to the muzzle according to different muzzle-target angles, firing distances, type of ammunition and weapon and barrel length. Based on a review of the literature and on the results of the experiments the authors could make the following statements of gunshot residues in angled contact and close contact gunshot: (1) gunshot residues on the target surface can be differentiated in a "inner" and "outer powder soot zone"; (2) the outer powder soot zone is much less visible than the inner powder soot zone and may lack on human skin; (3) with increasing muzzle target distance both inner and outer powder soot halo increase in size and decrease in density; (4) in angled shots the inner powder soot halo shows an eccentric, elliptic shape which points towards the muzzle, regardless of ammunition, calibre and barrel length; (5) the outer powder soot points away from the muzzle in angled contact and close contact shots.

A centerless grinding unit used for precisely processing ferrules of optical fiber connector

NASA Astrophysics Data System (ADS)

Wu, Yongbo; Kondo, Takahiro; Kato, Masana

2005-02-01

This paper describes the development of a centerless grinding unit used for precisely processing ferrules, a key component of optical fiber connectors. In conventional processing procedure, the outer diameter of a ferrule is ground by employing a special machine tool, i.e., centerless grinder. However, in the case of processing small amount of ferrules, introducing a centerless grinder leads to high processing cost. Therefore, in order to take measures against this problem, the present authors propose a new centerless grinding technique where a compact centerless grinding unit, which is composed of an ultrasonic elliptic-vibration shoe, a workrest blade, and their respective holders, is installed on a popular surface grinder to perform the centerless grinding operations for outer diameter machining of ferrules. In this work, a unit is designed and constructed, and is installed on a surface grinder equipped with a diamond grinding wheel. Then, the performance of the unit is examined experimentally followed by grinding tests of ferrule"s outer diameter. As a result, the roundness of the ferrule"s outer diameter improved from the original value of around 3μm to the final value of around 0.5 μm, confirming the validity of the new technique.

Histochemistry and ultrastructure of the metacercarial cysts of blackspot trematodes Uvulifer ambloplitis and Neascus pyriformis.

PubMed

Wittrock, D D; Bruce, C S; Johnson, A D

1991-06-01

Cysts of Uvulifer ambloplitis from green sunfish, Lepomis cyanellus, and Neascus pyriformis from red shiners, Notropis lutrensis, were studied with light-level histochemistry and scanning and transmission electron microscopy. Cysts of both species are bilayered, consisting of an outer host capsule and an inner parasite cyst; the space between these layers is filled with a viscous material. The outer portion of the host capsule of both species is composed of fibrocytes, melanin granules, and collagen fibrils, and the inner portion of layers of flattened fibrocytes. The parasite cyst of U. ambloplitis is formed of 2 layers, an outer dense layer and an inner light layer, whereas the parasite cyst of N. pyriformis is made of 3 layers. A thin outer light-staining layer is present in addition to the 2 layers observed in U. ambloplitis. Results of histochemical staining were the same for both species. The host capsule stained positively for proteins and neutral and acid mucopolysaccharides. The viscous material was positive for neutral and acid mucopolysaccharides but not for proteins. The parasite cyst gave a strong positive reaction for neutral mucopolysaccharides but was negative for acid mucopolysaccharides and proteins.

Rapid hydrogen ion uptake of rod outer segments and rhodopsin solutions on illumination

PubMed Central

Falk, G.; Fatt, P.

1966-01-01

1. Flash illumination of a suspension of frog rod outer segments or rhodopsin solution in contact with a platinum electrode produces a rapidly developing negative displacement of potential of the electrode (with respect to a reversible electrode). 2. The amplitude of the potential change varies inversely with the H+ buffering capacity of the medium. It is inferred that the response is due to an uptake of H+ by the rod outer segments or rhodopsin, with the platinum surface acting as a pH electrode. 3. Determination of the action spectrum shows that the response depends on the absorption of light by rhodopsin. 4. In frog rods one acid-binding group with a pK of about 7·9 is produced for each molecule of rhodopsin bleached, consistent with a rhodopsin concentration in frog rods of 1·7 mM. 5. It is suggested that the time course of the response with rhodopsin solutions reflects the kinetics of the conversion of metarhodopsin I to metarhodopsin II. 6. A slower time course of voltage change observed for suspensions of outer segments is attributable to the time required for the diffusion of H+ buffer out of the rods. PMID:5945249

Interstellar and Cometary Dust

NASA Technical Reports Server (NTRS)

Mathis, John S.

1997-01-01

'Interstellar dust' forms a continuum of materials with differing properties which I divide into three classes on the basis of observations: (a) diffuse dust, in the low-density interstellar medium; (b) outer-cloud dust, observed in stars close enough to the outer edges of molecular clouds to be observed in the optical and ultraviolet regions of the spectrum, and (c) inner-cloud dust, deep within the cores of molecular clouds, and observed only in the infrared by means of absorption bands of C-H, C=O, 0-H, C(triple bond)N, etc. There is a surprising regularity of the extinction laws between diffuse- and outer-cloud dust. The entire mean extinction law from infrared through the observable ultraviolet spectrum can be characterized by a single parameter. There are real deviations from this mean law, larger than observational uncertainties, but they are much smaller than differences of the mean laws in diffuse- and outer-cloud dust. This fact shows that there are processes which operate over the entire distribution of grain sizes, and which change size distributions extremely efficiently. There is no evidence for mantles on grains in local diffuse and outer-cloud dust. The only published spectra of the star VI Cyg 12, the best candidate for showing mantles, does not show the 3.4 micro-m band which appreciable mantles would produce. Grains are larger in outer-cloud dust than diffuse dust because of coagulation, not accretion of extensive mantles. Core-mantle grains favored by J. M. Greenberg and collaborators, and composite grains of Mathis and Whiffen (1989), are discussed more extensively (naturally, I prefer the latter). The composite grains are fluffy and consist of silicates, amorphous carbon, and some graphite in the same grain. Grains deep within molecular clouds but before any processing within the solar system are presumably formed from the accretion of icy mantles on and within the coagulated outer-cloud grains. They should contain a mineral/carbonaceous matrix, without organic refractory mantles, in between the ices. Unfortunately, they may be significantly processed by chemical processes accompanying the warming (over the 10 K of the dark cloud cores) which occurs in the outer solar system. Evidence of this processing is the chemical anomalies present in interplanetary dust particles collected in the stratosphere, which may be the most primitive materials we have obtained to date. The comet return mission would greatly clarify the situation, and probably provide samples of genuine interstellar grains.

Production of Ginkgo leaf-shaped basidiocarps of the Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes), containing high levels of α- and β-D-glucan and ganoderic acid A.

PubMed

Yajima, Yuka; Miyazaki, Minoru; Okita, Noriyasu; Hoshino, Tamotsu

2013-01-01

Ganoderic acid A and α- and β-D-glucan content were compared among morphologically different basidiocarps of the medicinal mushroom Ganoderma lucidum. Ginkgo leaf-shaped basidiocarps gradually hardened from the base to the pileus and accumulated a higher amount of bioactive components than normal (kidney-shaped) and antler/deer horn-shaped basidiocarps. In the normal G. lucidum stipe, the outer context contained the highest amount of α- and β-D-glucan (approximately 55%) and the highest amount of ganoderic acid A (approximately 0.3%). Ginkgo leaf-shaped G. lucidum had a large area of outer layer and stout outer context, which contributed to their high α- and β-D-glucan and ganoderic acid A content.

Large-Scale Integration of Solid-State Microfluidic Valves With No Moving Parts

DTIC Science & Technology

2005-01-01

compact and diffuse layer is called outer Helmholtz plane ( OHP ). Potential drop across the diffusion layer is called the zeta potential, ζ. As the...Gouy-Chapman model. This is shown in Fig. 3. The plane at x2 is called the outer Helmholtz plane ( OHP ). Then the total double layer capacitance Cd...Enhanced Electro-Osmotic Pumping With Liquid Bridge and Field Effect Flow Rectification, ” Presented in IEEE MEMS 2004 Conference, Maastricht, The

Bacterial social networks: structure and composition of Myxococcus xanthus outer membrane vesicle chains.

PubMed

Remis, Jonathan P; Wei, Dongguang; Gorur, Amita; Zemla, Marcin; Haraga, Jessica; Allen, Simon; Witkowska, H Ewa; Costerton, J William; Berleman, James E; Auer, Manfred

2014-02-01

The social soil bacterium, Myxococcus xanthus, displays a variety of complex and highly coordinated behaviours, including social motility, predatory rippling and fruiting body formation. Here we show that M. xanthus cells produce a network of outer membrane extensions in the form of outer membrane vesicle chains and membrane tubes that interconnect cells. We observed peritrichous display of vesicles and vesicle chains, and increased abundance in biofilms compared with planktonic cultures. By applying a range of imaging techniques, including three-dimensional (3D) focused ion beam scanning electron microscopy, we determined these structures to range between 30 and 60 nm in width and up to 5 μm in length. Purified vesicle chains consist of typical M. xanthus lipids, fucose, mannose, N-acetylglucosamine and N-acetylgalactoseamine carbohydrates and a small set of cargo protein. The protein content includes CglB and Tgl outer membrane proteins known to be transferable between cells in a contact-dependent manner. Most significantly, the 3D organization of cells within biofilms indicates that cells are connected via an extensive network of membrane extensions that may connect cells at the level of the periplasmic space. Such a network would allow the transfer of membrane proteins and other molecules between cells, and therefore could provide a mechanism for the coordination of social activities. © 2013 Society for Applied Microbiology and John Wiley & Sons Ltd.

Comparison of Performance of Experimental and Conventional Cage Designs and Materials for 75-millimeter-bore Cylindrical Roller Bearings at High Speed

NASA Technical Reports Server (NTRS)

Anderson, William J; Macks, E Fred; Nemeth, Zolton N

1954-01-01

The results of two investigations, one to determine the relative merits of four experimental and two conventional design 75-millimeter-bore (size 215) cylindrical roller bearings and one to determine the relative merits of nodular iron and bronze as cage materials for this size and type of bearing, are presented in this report. Nine test bearings were operated over a range of dn values (product of bearing bore in mm and shaft speed in r.p.m) from 0.3 x 10(6) to 2.3 x 20(6), radial loads for 7 to 1613 pounds, and oil flows from 2 to 8 pounds per minute with a single-jet circulatory oil feed. Of the six bearings used to evaluate designs, four were experimental types with outer-race-riding cages and inner-race-guided rollers, and two were conventional types, one with outer-race-guided rollers and cage and one with inner-race-guided rollers and cage. Each of these six test bearings was equipped with a different design cage made of nodular iron. The experimental combination of an outer-race-riding cage with a straight-through outer race and inner-race-guided rollers was found to give the best over-all performance based on limiting dn values and bearing temperatures.

Inhibition or Stimulation of Autophagy Affects Early Formation of Lipofuscin-Like Autofluorescence in the Retinal Pigment Epithelium Cell

PubMed Central

Lei, Lei; Tzekov, Radouil; Li, Huapeng; McDowell, J. Hugh; Gao, Guangping; Smith, W. Clay; Tang, Shibo; Kaushal, Shalesh

2017-01-01

The accumulation of lipofuscin in the retinal pigment epithelium (RPE) is dependent on the effectiveness of photoreceptor outer segment material degradation. This study explored the role of autophagy in the fate of RPE lipofuscin degradation. After seven days of feeding with either native or modified rod outer segments, ARPE-19 cells were treated with enhancers or inhibitors of autophagy and the autofluorescence was detected by fluorescence-activated cell sorting. Supplementation with different types of rod outer segments increased lipofuscin-like autofluorescence (LLAF) after the inhibition of autophagy, while the induction of autophagy (e.g., application of rapamycin) decreased LLAF. The effects of autophagy induction were further confirmed by Western blotting, which showed the conversion of LC3-I to LC3-II, and by immunofluorescence microscopy, which detected the lysosomal activity of the autophagy inducers. We also monitored LLAF after the application of several autophagy inhibitors by RNA-interference and confocal microscopy. The results showed that, in general, the inhibition of the autophagy-related proteins resulted in an increase in LLAF when cells were fed with rod outer segments, which further confirms the effect of autophagy in the fate of RPE lipofuscin degradation. These results emphasize the complex role of autophagy in modulating RPE autofluorescence and confirm the possibility of the pharmacological clearance of RPE lipofuscin by small molecules. PMID:28353645

Use of hydrodynamic forces to engineer cartilaginous tissues resembling the non-uniform structure and function of meniscus.

PubMed

Marsano, Anna; Wendt, David; Raiteri, Roberto; Gottardi, Riccardo; Stolz, Martin; Wirz, Dieter; Daniels, Alma U; Salter, Donald; Jakob, Marcel; Quinn, Thomas M; Martin, Ivan

2006-12-01

The aim of this study was to demonstrate that differences in the local composition of bi-zonal fibrocartilaginous tissues result in different local biomechanical properties in compression and tension. Bovine articular chondrocytes were loaded into hyaluronan-based meshes (HYAFF-11) and cultured for 4 weeks in mixed flask, a rotary Cell Culture System (RCCS), or statically. Resulting tissues were assessed histologically, immunohistochemically, by scanning electron microscopy and mechanically in different regions. Local mechanical analyses in compression and tension were performed by indentation-type scanning force microscopy and by tensile tests on punched out concentric rings, respectively. Tissues cultured in mixed flask or RCCS displayed an outer region positively stained for versican and type I collagen, and an inner region positively stained for glycosaminoglycans and types I and II collagen. The outer fibrocartilaginous capsule included bundles (up to 2 microm diameter) of collagen fibers and was stiffer in tension (up to 3.6-fold higher elastic modulus), whereas the inner region was stiffer in compression (up to 3.8-fold higher elastic modulus). Instead, molecule distribution and mechanical properties were similar in the outer and inner regions of statically grown tissues. In conclusion, exposure of articular chondrocyte-based constructs to hydrodynamic flow generated tissues with locally different composition and mechanical properties, resembling some aspects of the complex structure and function of the outer and inner zones of native meniscus.

The unexpected mechanism underlying the high-valent mono-oxo-rhenium(V) hydride catalyzed hydrosilylation of C=N functionalities: insights from a DFT study.

PubMed

Wang, Jiandi; Wang, Wenmin; Huang, Liangfang; Yang, Xiaodi; Wei, Haiyan

2015-04-07

In this study, we theoretically investigated the mechanism underlying the high-valent mono-oxo-rhenium(V) hydride Re(O)HCl2(PPh3)2 (1) catalyzed hydrosilylation of C=N functionalities. Our results suggest that an ionic S(N)2-Si outer-sphere pathway involving the heterolytic cleavage of the Si-H bond competes with the hydride pathway involving the C=N bond inserted into the Re-H bond for the rhenium hydride (1) catalyzed hydrosilylation of the less steric C=N functionalities (phenylmethanimine, PhCH=NH, and N-phenylbenzylideneimine, PhCH=NPh). The rate-determining free-energy barriers for the ionic outer-sphere pathway are calculated to be ∼28.1 and 27.6 kcal mol(-1), respectively. These values are slightly more favorable than those obtained for the hydride pathway (by ∼1-3 kcal mol(-1)), whereas for the large steric C=N functionality of N,1,1-tri(phenyl)methanimine (PhCPh=NPh), the ionic outer-sphere pathway (33.1 kcal mol(-1)) is more favorable than the hydride pathway by as much as 11.5 kcal mol(-1). Along the ionic outer-sphere pathway, neither the multiply bonded oxo ligand nor the inherent hydride moiety participate in the activation of the Si-H bond. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Masers in Disks due to Gravitational Instabilities

NASA Astrophysics Data System (ADS)

Mejia, A. C.; Durisen, R. H.; Pickett, B. K.; Hartquist, T. W.

2001-12-01

Evidence suggests that some masers associated with massive protostars may originate in the outer regions of large circumstellar disks, at radii of 100's to 1000's of AU from the central mass. This is particularly true for methanol (CH3OH), where linear distributions of masers are found with disk-like kinematics. In 3D hydrodynamics simulations we have made to study the effects of gravitational instabilities in the outer parts of disks around young low-mass stars, the nonlinear development of the instabilities leads to a complex of intersecting spiral shocks, clumps, and arclets within the disk and to significant time-dependent, nonaxisymmetric distortions of the disk surface. A rescaling of our disk simulations to the case of a massive protostar shows that conditions in the disturbed outer disk seem conducive to the appearance of masers if it is viewed edge-on. This work was supported by NASA Origins Program Grant NAGW5-4342, by the Alexander von Humboldt Foundation, and by NASA Planetary Geology and Geophysics Program Grant NAG5-10262.

Static length changes of cochlear outer hair cells can tune low-frequency hearing

PubMed Central

Ciganović, Nikola; Warren, Rebecca L.; Keçeli, Batu; Jacob, Stefan

2018-01-01

The cochlea not only transduces sound-induced vibration into neural spikes, it also amplifies weak sound to boost its detection. Actuators of this active process are sensory outer hair cells in the organ of Corti, whereas the inner hair cells transduce the resulting motion into electric signals that propagate via the auditory nerve to the brain. However, how the outer hair cells modulate the stimulus to the inner hair cells remains unclear. Here, we combine theoretical modeling and experimental measurements near the cochlear apex to study the way in which length changes of the outer hair cells deform the organ of Corti. We develop a geometry-based kinematic model of the apical organ of Corti that reproduces salient, yet counter-intuitive features of the organ’s motion. Our analysis further uncovers a mechanism by which a static length change of the outer hair cells can sensitively tune the signal transmitted to the sensory inner hair cells. When the outer hair cells are in an elongated state, stimulation of inner hair cells is largely inhibited, whereas outer hair cell contraction leads to a substantial enhancement of sound-evoked motion near the hair bundles. This novel mechanism for regulating the sensitivity of the hearing organ applies to the low frequencies that are most important for the perception of speech and music. We suggest that the proposed mechanism might underlie frequency discrimination at low auditory frequencies, as well as our ability to selectively attend auditory signals in noisy surroundings. PMID:29351276

Effects of semi-floating ring bearing outer clearance on the subsynchronous oscillation of turbocharger rotor

NASA Astrophysics Data System (ADS)

Liang, Feng; Zhou, Ming; Xu, Quanyong

2016-09-01

Semi-floating ring bearing(SFRB) is developed to control the vibration of turbocharger rotor. The outer clearance of SFRB affects the magnitude and frequency of nonlinear whirl motion, which is significant for the design of turbocharger. In order to explore the effects of outer clearance, a transient finite element analysis program for rotor and oil film bearing is built and validated by a published experimental case. The nonlinear dynamic behaviors of rotor-SFRB system are simulated. According to the simulation results, two representative subsynchronous oscillations excited by the two bearings respectively are discovered. As the outer clearance of SFRB increases from 24 μm to 60 μm, the low-frequency subsynchronous oscillation experiences three steps, including a strong start, a gradual recession and a combination with the other one. At the same time, the high-frequency subsynchronous oscillation starts to appear gradually, then strengthens, and finally combines. If gravity and unbalance are neglected, the combination will start starts from high rotor speed and extents to low rotor speed, just like a "zipper". It is found from the quantitative analysis that when the outer clearance increases, the vibration amplitude experiences large value firstly, then reduction, and suddenly increasing after combination. A useful design principle of SFRB outer clearance for minimum vibration amplitude is proposed: the outer clearance value should be chosen to keep the frequency of two subsynchronous oscillations clearly separated and their amplitudes close.

En face spectral domain optical coherence tomography analysis of lamellar macular holes.

PubMed

Clamp, Michael F; Wilkes, Geoff; Leis, Laura S; McDonald, H Richard; Johnson, Robert N; Jumper, J Michael; Fu, Arthur D; Cunningham, Emmett T; Stewart, Paul J; Haug, Sara J; Lujan, Brandon J

2014-07-01

To analyze the anatomical characteristics of lamellar macular holes using cross-sectional and en face spectral domain optical coherence tomography. Forty-two lamellar macular holes were retrospectively identified for analysis. The location, cross-sectional length, and area of lamellar holes were measured using B-scans and en face imaging. The presence of photoreceptor inner segment/outer segment disruption and the presence or absence of epiretinal membrane formation were recorded. Forty-two lamellar macular holes were identified. Intraretinal splitting occurred within the outer plexiform layer in 97.6% of eyes. The area of intraretinal splitting in lamellar holes did not correlate with visual acuity. Eyes with inner segment/outer segment disruption had significantly worse mean logMAR visual acuity (0.363 ± 0.169; Snellen = 20/46) than in eyes without inner segment/outer segment disruption (0.203 ± 0.124; Snellen = 20/32) (analysis of variance, P = 0.004). Epiretinal membrane was present in 34 of 42 eyes (81.0%). En face imaging allowed for consistent detection and quantification of intraretinal splitting within the outer plexiform layer in patients with lamellar macular holes, supporting the notion that an area of anatomical weakness exists within Henle's fiber layer, presumably at the synaptic connection of these fibers within the outer plexiform layer. However, the en face area of intraretinal splitting did not correlate with visual acuity, disruption of the inner segment/outer segment junction was associated with significantly worse visual acuity in patients with lamellar macular holes.

Shoulder and hip joints for hard space suits and the like

NASA Technical Reports Server (NTRS)

Vykukal, H. C.

1986-01-01

For use in hard space suits and the like, a joint between the torso covering and the upper arm covering (i.e., shoulder) or between the torso covering and upper leg covering (i.e., hip) is disclosed. Each joint has an outer covering and a inner covering. The outer covering has plural perferably truncated toroidal sections decreasing in size proceeding outwardly. In one embodiment at each joint there are two bearings, the first larger than the second. The outer race of the larger bearing is attached to the outer edge of the smaller end of each section and the inner race of the larger bearing is attached to the end wall. The inner race of the smaller bearing is attached to the end wall. The outer race of the smaller bearing is attached to the larger end of the next section. Each bearing hask appropriate seals. Between each section is a rubber ring for the comfort of the wearer. Such rubber rings have radial flanges attached to the inner races of two adjacent bearings. Matching semicircular grooves are formed in the abutting overlapping surfaces. Bellows-like inner walls are also provided for each section fixed at one end to an inner cylindrical flange and, at the opposite end, to an end wall. Each outer section may rotate 360 deg relative to the next outer section, whereas the bellows sections do not rotate, but rather expand or contract locally as the rigid sections rotate relative to each other.

Atmospheric Mining in the Outer Solar System: Outer Planet Orbital Transfer and Lander Analyses

NASA Technical Reports Server (NTRS)

Palaszewski, Bryan

2016-01-01

Atmospheric mining in the outer solar system has been investigated as a means of fuel production for high energy propulsion and power. Fusion fuels such as Helium 3 (3He) and deuterium can be wrested from the atmospheres of Uranus and Neptune and either returned to Earth or used in-situ for energy production. Helium 3 and deuterium were the primary gases of interest with hydrogen being the primary propellant for nuclear thermal solid core and gas core rocket-based atmospheric flight. A series of analyses were undertaken to investigate resource capturing aspects of atmospheric mining in the outer solar system. This included the gas capturing rate, storage options, and different methods of direct use of the captured gases. While capturing 3He, large amounts of hydrogen and 4He are produced. Analyses of orbital transfer vehicles (OTVs), landers, and the issues with in-situ resource utilization (ISRU) mining factories are included. Preliminary observations are presented on near-optimal selections of moon base orbital locations, OTV power levels, and OTV and lander rendezvous points. For analyses of round trip OTV flights from Uranus to Miranda or Titania, a 10-Megawatt electric (MWe) OTV power level and a 200-metric ton (MT) lander payload were selected based on a relative short OTV trip time and minimization of the number of lander flights. A similar optimum power level is suggested for OTVs flying from low orbit around Neptune to Thalassa or Triton. Several moon base sites at Uranus and Neptune and the OTV requirements to support them are also addressed.

Atmospheric Mining in the Outer Solar System: Outer Planet Orbital Transfer and Lander Analyses

NASA Technical Reports Server (NTRS)

Palaszewski, Bryan

2016-01-01

Atmospheric mining in the outer solar system has been investigated as a means of fuel production for high energy propulsion and power. Fusion fuels such as Helium 3 (3He) and deuterium can be wrested from the atmospheres of Uranus and Neptune and either returned to Earth or used in-situ for energy production. Helium 3 and deuterium were the primary gases of interest with hydrogen being the primary propellant for nuclear thermal solid core and gas core rocket-based atmospheric flight. A series of analyses were undertaken to investigate resource capturing aspects of atmospheric mining in the outer solar system. This included the gas capturing rate, storage options, and different methods of direct use of the captured gases. While capturing 3He, large amounts of hydrogen and 4He are produced. Analyses of orbital transfer vehicles (OTVs), landers, and the issues with in-situ resource utilization (ISRU) mining factories are included. Preliminary observations are presented on near-optimal selections of moon base orbital locations, OTV power levels, and OTV and lander rendezvous points. For analyses of round trip OTV flights from Uranus to Miranda or Titania, a 10- Megawatt electric (MWe) OTV power level and a 200 metricton (MT) lander payload were selected based on a relative short OTV trip time and minimization of the number of lander flights. A similar optimum power level is suggested for OTVs flying from low orbit around Neptune to Thalassa or Triton. Several moon base sites at Uranus and Neptune and the OTV requirements to support them are also addressed.

Observation of a 3D Magnetic Null Point

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romano, P.; Falco, M.; Guglielmino, S. L.

2017-03-10

We describe high-resolution observations of a GOES B-class flare characterized by a circular ribbon at the chromospheric level, corresponding to the network at the photospheric level. We interpret the flare as a consequence of a magnetic reconnection event that occurred at a three-dimensional (3D) coronal null point located above the supergranular cell. The potential field extrapolation of the photospheric magnetic field indicates that the circular chromospheric ribbon is cospatial with the fan footpoints, while the ribbons of the inner and outer spines look like compact kernels. We found new interesting observational aspects that need to be explained by models: (1)more » a loop corresponding to the outer spine became brighter a few minutes before the onset of the flare; (2) the circular ribbon was formed by several adjacent compact kernels characterized by a size of 1″–2″; (3) the kernels with a stronger intensity emission were located at the outer footpoint of the darker filaments, departing radially from the center of the supergranular cell; (4) these kernels started to brighten sequentially in clockwise direction; and (5) the site of the 3D null point and the shape of the outer spine were detected by RHESSI in the low-energy channel between 6.0 and 12.0 keV. Taking into account all these features and the length scales of the magnetic systems involved in the event, we argue that the low intensity of the flare may be ascribed to the low amount of magnetic flux and to its symmetric configuration.« less

Propagation of Interplanetary Disturbances in the Outer Heliosphere

NASA Technical Reports Server (NTRS)

Wang, Chi

2005-01-01

Contents include the following: 1. We have developed a one-dimensional, spherically symmetric, multi-fluid MHD model that includes solar wind protons and electrons, pickup ions, and interstellar neutral hydrogen. This model advances the existing solar wind models for the outer heliosphere in two important ways: one is that it distinguishes solar wind protons from pickup ions, and the other is that it allows for energy transfer from pickup ions to the solar wind protons. Model results compare favorably with the Voyager 2 observations. 2. 2. Solar wind slowdown and interstellar neutral density. The solar wind in the outer heliosphere is fundamentally different from that in the inner heliosphere since the effects of interstellar neutrals become significant. 3. ICME propagation from the inner to outer heliosphere. Large coronal mass ejections (CMEs) have major effects on the structure of the solar wind and the heliosphere. The plasma and magnetic field can be compressed ahead of interplanetary CMEs. 4. During the current solar cycle (Cycle 23), several major CMEs associated with solar flares produced large transient shocks which were observed by widely-separated spacecraft such as Wind at Earth and Voyager 2 beyond 60 AU. Using data from these spacecraft, we use the multi-fluid model to investigate shock propagation and interaction in the heliosphere. Specifically, we studied the Bastille Day 2000, April 2001 and Halloween 2003 events. 5. Statistical properties of the solar wind in the outer heliosphere. In a collaboration with L.F. Burlaga of GSFC, it is shown that the basic statistical properties of the solar wind in the outer heliosphere can be well produced by our model. We studied the large-scale heliospheric magnetic field strength fluctuations as a function of distance from the Sun during the declining phase of a solar cycle, using our numerical model with observations made at 1 AU during 1995 as input. 6. Radial heliospheric magnetic field events. The heliospheric magnetic field (HMF) direction, on average, conforms well to the Parker spiral.

In vivo evidence of TonB shuttling between the cytoplasmic and outer membrane in Escherichia coli.

PubMed

Larsen, Ray A; Letain, Tracy E; Postle, Kathleen

2003-07-01

Gram-negative bacteria are able to convert potential energy inherent in the proton gradient of the cytoplasmic membrane into active nutrient transport across the outer membrane. The transduction of energy is mediated by TonB protein. Previous studies suggest a model in which TonB makes sequential and cyclic contact with proteins in each membrane, a process called shuttling. A key feature of shuttling is that the amino-terminal signal anchor must quit its association with the cytoplasmic membrane, and TonB becomes associated solely with the outer membrane. However, the initial studies did not exclude the possibility that TonB was artifactually pulled from the cytoplasmic membrane by the fractionation process. To resolve this ambiguity, we devised a method to test whether the extreme TonB amino-terminus, located in the cytoplasm, ever became accessible to the cys-specific, cytoplasmic membrane-impermeant molecule, Oregon Green(R) 488 maleimide (OGM) in vivo. A full-length TonB and a truncated TonB were modified to carry a sole cysteine at position 3. Both full-length TonB and truncated TonB (consisting of the amino-terminal two-thirds) achieved identical conformations in the cytoplasmic membrane, as determined by their abilities to cross-link to the cytoplasmic membrane protein ExbB and their abilities to respond conformationally to the presence or absence of proton motive force. Full-length TonB could be amino-terminally labelled in vivo, suggesting that it was periplasmically exposed. In contrast, truncated TonB, which did not associate with the outer membrane, was not specifically labelled in vivo. The truncated TonB also acted as a control for leakage of OGM across the cytoplasmic membrane. Further, the extent of labelling for full-length TonB correlated roughly with the proportion of TonB found at the outer membrane. These findings suggest that TonB does indeed disengage from the cytoplasmic membrane during energy transduction and shuttle to the outer membrane.

Glove and gown effects on intraoperative bacterial contamination.

PubMed

Ward, William G; Cooper, Joshua M; Lippert, Dylan; Kablawi, Rawan O; Neiberg, Rebecca H; Sherertz, Robert J

2014-03-01

Experiments were performed to determine the risk of bacterial contamination associated with changing outer gloves and using disposable spunlace paper versus reusable cloth gowns. Despite decades of research, there remains a lack of consensus regarding certain aspects of optimal aseptic technique including outer glove exchange while double-gloving and surgical gown type selection. In an initial glove study, 102 surgical team members were randomized to exchange or retain outer gloves 1 hour into clean orthopedic procedures; cultures were obtained 15 minutes later from the palm of the surgeon's dominant gloved hand and from the surgical gown sleeve. Surgical gown type selection was recorded. A laboratory strike-through study investigating bacterial transmission through cloth and paper gowns was performed with coagulase-negative staphylococci. In a follow-up glove study, 251 surgical team members, all wearing paper gowns, were randomized as in the first glove study. Glove study 1 revealed 4-fold higher levels of baseline bacterial contamination (31% vs 7%) on the sleeve of surgical team members wearing cloth gowns than those using paper gowns [odds ratio (95% confidence interval): 4.64 (1.72-12.53); P = 0.0016]. The bacterial strike-through study revealed that 26 of 27 cloth gowns allowed bacterial transmission through the material compared with 0 of 27 paper gowns (P < 0.001). In glove study 2, surgeons retaining outer gloves 1 hour into the case had a subsequent positive glove contamination rate of 23% compared with 13% among surgeons exchanging their original outer glove [odds ratio (95% confidence interval): 1.97 (1.02-3.80); P = 0.0419]. Paper gowns demonstrated less bacterial transmission in the laboratory and lower rates of contamination in the operating room. Disposable paper gowns are recommended for all surgical cases, especially those involving implants, because of the heightened risk of infection. Outer glove exchange just before handling implant materials is also recommended to minimize intraoperative contamination.

NUCLEAR POWER PLANT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Preece, G.E.; Bell, F.R.

1963-06-26

A protective arrangement is designed for shielding the environment and for preventing the leakage of radioactive gases from a ship nuclear power plant. In this arrangement, the core has inner and outer pressure vessels and a biological shielding around the outer pressure vessel. The shielding comprises a series of steel cylindrical shells immersed in water, and its inner wall may comprise part of the outer pressure vessel. (D.L.C.)

Disk filter

DOEpatents

Bergman, Werner

1986-01-01

An electric disk filter provides a high efficiency at high temperature. A hollow outer filter of fibrous stainless steel forms the ground electrode. A refractory filter material is placed between the outer electrode and the inner electrically isolated high voltage electrode. Air flows through the outer filter surfaces through the electrified refractory filter media and between the high voltage electrodes and is removed from a space in the high voltage electrode.

Article having an improved platinum-aluminum-hafnium protective coating

NASA Technical Reports Server (NTRS)

Nagaraj, Bangalore Aswatha (Inventor); Williams, Jeffrey Lawrence (Inventor)

2005-01-01

An article protected by a protective coating has a substrate and a protective coating having an outer layer deposited upon the substrate surface and a diffusion zone formed by interdiffusion of the outer layer and the substrate. The protective coating includes platinum, aluminum, no more than about 2 weight percent hafnium, and substantially no silicon. The outer layer is substantially a single phase.

75 FR 55970 - Safety Zone; VERMILION 380A at Block 380 Outer Continental Shelf Fixed Platform in the Gulf of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-15

...-AA00 Safety Zone; VERMILION 380A at Block 380 Outer Continental Shelf Fixed Platform in the Gulf of... safety zone around VERMILION 380A, a fixed platform, at Block 380 in the Outer Continental Shelf, approximately 90 miles south of Vermilion Bay, Louisiana. The fixed platform is on fire and the safety zone is...

Glass/Epoxy Door Panel for Automobiles

NASA Technical Reports Server (NTRS)

Bauer, J. L. JR.

1985-01-01

Lightweight panel cost-effective. Integrally-molded intrusion strap key feature of composite outer door panel. Strap replaces bulky and heavy steel instrusion beam of conventional door. Standard steel inner panel used for demonstration purposes. Door redesigned to exploit advantages of composite outer panel thinner. Outer panel for automobilie door, made of glass/epoxy composite material, lighter than conventional steel door panel, meets same strength requirements, and less expensive.

Maintaining Peace in Outer Space. Conference on the United Nations of the Next Decade (17th, Cooperstown, NY, June 19-24, 1982).

ERIC Educational Resources Information Center

Stanley Foundation, Muscatine, IA.

This is a report of a conference held to discuss maintaining peace in outer space. Nineteen space specialists participated in the conference. Topics discussed were recent technological developments, international cooperation for peaceful uses of outer space, prevention of weapons in space, and the future role of the United Nations. The report's…

Rapid analysis of inner and outer bark composition of southern yellow pine bark from industrial sources

Treesearch

Chi-Leung So; Thomas L. Eberhardt

2006-01-01

Differences in bark chemistry between inner and outer bark are well known and may affect the suitability of various bark supplies for a particular application. Accordingly, there is a need for quality control protocols to assess variability and predict product yields. Southern yellow pine bark samples from two industrial sources were separated into inner and outer bark...

Disk filter

DOEpatents

Bergman, W.

1985-01-09

An electric disk filter provides a high efficiency at high temperature. A hollow outer filter of fibrous stainless steel forms the ground electrode. A refractory filter material is placed between the outer electrode and the inner electrically isolated high voltage electrode. Air flows through the outer filter surfaces through the electrified refractory filter media and between the high voltage electrodes and is removed from a space in the high voltage electrode.

Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body.

PubMed

Worrall, L J; Hong, C; Vuckovic, M; Deng, W; Bergeron, J R C; Majewski, D D; Huang, R K; Spreter, T; Finlay, B B; Yu, Z; Strynadka, N C J

2016-12-14

The type III secretion (T3S) injectisome is a specialized protein nanomachine that is critical for the pathogenicity of many Gram-negative bacteria, including purveyors of plague, typhoid fever, whooping cough, sexually transmitted infections and major nosocomial infections. This syringe-shaped 3.5-MDa macromolecular assembly spans both bacterial membranes and that of the infected host cell. The internal channel formed by the injectisome allows for the direct delivery of partially unfolded virulence effectors into the host cytoplasm. The structural foundation of the injectisome is the basal body, a molecular lock-nut structure composed predominantly of three proteins that form highly oligomerized concentric rings spanning the inner and outer membranes. Here we present the structure of the prototypical Salmonella enterica serovar Typhimurium pathogenicity island 1 basal body, determined using single-particle cryo-electron microscopy, with the inner-membrane-ring and outer-membrane-ring oligomers defined at 4.3 Å and 3.6 Å resolution, respectively. This work presents the first, to our knowledge, high-resolution structural characterization of the major components of the basal body in the assembled state, including that of the widespread class of outer-membrane portals known as secretins.

Sizes of the Smallest Particles at Saturn Ring Edges from Diffraction in UVIS Stellar Occultations

NASA Astrophysics Data System (ADS)

Eckert, S.; Colwell, J. E.; Becker, T. M.; Esposito, L. W.

2017-12-01

Cassini's Ultraviolet Imaging Spectrograph (UVIS) has observed more than 150 ring stellar occultations since its arrival at Saturn in 2004. We use stellar occultation data from the UVIS High Speed Photometer (HSP) to identify diffraction signals at ring edges caused by small particles diffracting light into the detector and consequently increasing the signal above that of the unocculted star. The shape of a diffraction signal is indicative of the particle size distribution at the ring edge, which may be a dynamically perturbed region. Becker et al. (2015 Icarus doi:10.1016/j.icarus.2015.11.001) analyzed diffraction signals at the outer edge of the A Ring and the edges of the Encke Gap. We apply the Becker et al. (2015) model to the outer edge of the B Ring as well as the edges of ringlets within the C Ring and Cassini Division. In addition, we analyze diffraction signatures at the A Ring outer edge in 2 new occultations. The best-fit model signals to these occultations are consistent with the findings of Becker et al. (2015) who found an average minimum particle size amin =4.5 mm and average power law slope q=3.2. At the B Ring outer edge, we detect a diffraction signal in 10 of 28 occultations in which the diffraction signal would be observable according to our criteria for star brightness and observation geometry. We find a mean amin =11 mm and a mean q=3.0. At both edges of the so-called "Strange" ringlet (R6) we find a mean amin = 20 mm and mean q values of 3.0 and 2.8 at the inner and outer edges, respectively. In contrast, we do not observe any clear diffraction signals at either edge of the wider Huygens ringlet. This could imply an absence of cm-scale or smaller particles and indicates that collisions here may be less vigorous than at the other ring edges analyzed in this study. We detect diffraction in a small fraction ( 10%) of occultations at 3 ringlets within the Cassini Division: the Herschel ringlet, the Laplace ringlet, and the Barnard ringlet. We also found diffraction signals in only 2 of 30 occultations of the Maxwell ringlet in the C Ring. These ringlet diffraction signals, when present, indicate larger minimum particle sizes than seen in the outer A Ring and B ring edge.

Substrate system for spray forming

DOEpatents

Chu, Men G.; Chernicoff, William P.

2000-01-01

A substrate system for receiving a deposit of sprayed metal droplets including a movable outer substrate on which the sprayed metal droplets are deposited. The substrate system also includes an inner substrate disposed adjacent the outer substrate where the sprayed metal droplets are deposited on the outer substrate. The inner substrate includes zones of differing thermal conductivity to resist substrate layer porosity and to resist formation of large grains and coarse constituent particles in a bulk layer of the metal droplets which have accumulated on the outer substrate. A spray forming apparatus and associated method of spray forming a molten metal to form a metal product using the substrate system of the invention is also provided.

Substrate system for spray forming

DOEpatents

Chu, Men G.; Chernicoff, William P.

2002-01-01

A substrate system for receiving a deposit of sprayed metal droplets including a movable outer substrate on which the sprayed metal droplets are deposited. The substrate system also includes an inner substrate disposed adjacent the outer substrate where the sprayed metal droplets are deposited on the outer substrate. The inner substrate includes zones of differing thermal conductivity to resist substrate layer porosity and to resist formation of large grains and coarse constituent particles in a bulk layer of the metal droplets which have accumulated on the outer substrate. A spray forming apparatus and associated method of spray forming a molten metal to form a metal product using the substrate system of the invention is also provided.

Self-sterilization of bodies during outer planet entry

NASA Technical Reports Server (NTRS)

Hoffman, A. R.; Jaworski, W.; Taylor, D. M.

1974-01-01

A body encountering the atmosphere of an outer planet is subjected to heat loads which could result in high temperature conditions that render terrestrial organisms on or within the body nonviable. To determine whether an irregularly shaped entering body, consisting of several different materials, would be sterilized during inadvertent entry at high velocity, the thermal response of a typical outer planet spacecraft instrument was studied. The results indicate that the Teflon insulated cable and electronic circuit boards may not experience sterilizing temperatures during a Jupiter, Saturn, or Titan entry. Another conclusion of the study is that small plastic particles entering Saturn from outer space have wider survival corridors than do those at Jupiter.

MHD processes in the outer heliosphere

NASA Technical Reports Server (NTRS)

Burlaga, L. F.

1984-01-01

The magnetic field measurements from Voyager and the magnetohydrodynamic (MHD) processes in the outer heliosphere are reviewed. A bibliography of the experimental and theoretical work concerning magnetic fields and plasmas observed in the outer heliosphere is given. Emphasis in this review is on basic concepts and dynamical processes involving the magnetic field. The theory that serves to explain and unify the interplanetary magnetic field and plasma observations is magnetohydrodynamics. Basic physical processes and observations that relate directly to solutions of the MHD equations are emphasized, but obtaining solutions of this complex system of equations involves various assumptions and approximations. The spatial and temporal complexity of the outer heliosphere and some approaches for dealing with this complexity are discussed.

Direct Communication to Earth from Probes

NASA Technical Reports Server (NTRS)

Bolton, Scott J.; Folkner, William M.; Abraham, Douglas S.

2005-01-01

A viewgraph presentation on outer planetary probe communications to Earth is shown. The topics include: 1) Science Rational for Atmospheric Probes to the Outer Planets; 2) Controlling the Scientific Appetite; 3) Learning more about Jupiter before we send more probes; 4) Sample Microwave Scan From Juno; 5) Jupiter s Deep Interior; 6) The Square Kilometer Array (SKA): A Breakthrough for Radio Astronomy; 7) Deep Space Array-based Network (DSAN); 8) Probe Direct-to-Earth Data Rate Calculations; 9) Summary; and 10) Enabling Ideas.

AGB and post-AGB objects in the outer Galaxy

NASA Astrophysics Data System (ADS)

Szczerba, Ryszard; Yung, Bosco H. K.; Sewiło, Marta; Siódmiak, Natasza; Karska, Agata

2017-10-01

We present the results of our search for low- and intermediate mass evolved stars in the outer Galaxy using AllWISE catalogue photometry. We show that the [3.4]-[12] vs. [4.6]-[22] colour-colour diagram is most suitable for separating C-rich/O-rich AGB and post-AGB star candidates. We are able to select 2,510 AGB and 24,821 post-AGB star candidates. However, the latter are severely mixed with the known young stellar objects in this diagram.

Studies of volatiles and organic materials in early terrestrial and present-day outer solar system environments

NASA Technical Reports Server (NTRS)

Sagan, Carl; Thompson, W. Reid; Chyba, Christopher F.; Khare, B. N.

1991-01-01

A review and partial summary of projects within several areas of research generally involving the origin, distribution, chemistry, and spectral/dielectric properties of volatiles and organic materials in the outer solar system and early terrestrial environments are presented. The major topics covered include: (1) impact delivery of volatiles and organic compounds to the early terrestrial planets; (2) optical constants measurements; (3) spectral classification, chemical processes, and distribution of materials; and (4) radar properties of ice, hydrocarbons, and organic heteropolymers.

Monodeurated methane in the outer solar system. 2. Its detection on Uranus at 1.6 microns

NASA Technical Reports Server (NTRS)

Debergh, C.; Lutz, B. L.; Owen, T.; Brault, J.; Chauville, J.

1985-01-01

Deuterium in the atmosphere of Uranus has been studied only via measurements of the exceedingly weak dipole lines of hydrogen-deuteride (HD) seen in the visible region of the spectrum. The other sensitive indicator of deuterium in the outer solar system is monodeuterated methane (CH3D) but the two bands normally used ot study this molecule, NU sub 2 near 2200 1/cm and NU sub 6 near 1161 1/cm, have not been detected in Uranus.

Multiple bottlenecks in hierarchical control of action sequences: what does "response selection" select in skilled typewriting?

PubMed

Yamaguchi, Motonori; Logan, Gordon D; Li, Vanessa

2013-08-01

Does response selection select words or letters in skilled typewriting? Typing performance involves hierarchically organized control processes: an outer loop that controls word level processing, and an inner loop that controls letter (or keystroke) level processing. The present study addressed whether response selection occurs in the outer loop or the inner loop by using the psychological refractory period (PRP) paradigm in which Task1 required typing single words and Task2 required vocal responses to tones. The number of letters (string length) in the words was manipulated to discriminate selection of words from selection of keystrokes. In Experiment 1, the PRP effect depended on string length of words in Task1, suggesting that response selection occurs in the inner loop. To assess contributions of the outer loop, the influence of string length was examined in a lexical-decision task that also involves word encoding and lexical access (Experiment 2), or to-be-typed words were preexposed so outer-loop processing could finish before typing started (Experiment 3). Response time for Task2 (RT2) did not depend on string length with lexical decision, and RT2 still depended on string length with typing preexposed strings. These results support the inner-loop locus of the PRP effect. In Experiment 4, typing was performed as Task2, and the effect of string length on typing RT interacted with stimulus onset asynchrony superadditively, implying that another bottleneck also exists in the outer loop. We conclude that there are at least two bottleneck processes in skilled typewriting. 2013 APA, all rights reserved

Hydrophilic excipients modulate the time lag of time-controlled disintegrating press-coated tablets.

PubMed

Lin, Shan-Yang; Li, Mei-Jane; Lin, Kung-Hsu

2004-08-16

An oral press-coated tablet was developed by means of direct compression to achieve the time-controlled disintegrating or rupturing function with a distinct predetermined lag time. This press-coated tablet containing sodium diclofenac in the inner core was formulated with an outer shell by different weight ratios of hydrophobic polymer of micronized ethylcellulose (EC) powder and hydrophilic excipients such as spray-dried lactose (SDL) or hydroxypropyl methylcellulose (HPMC). The effect of the formulation of an outer shell comprising both hydrophobic polymer and hydrophilic excipients on the time lag of drug release was investigated. The release profile of the press-coated tablet exhibited a time period without drug release (time lag) followed by a rapid and complete release phase, in which the outer shell ruptured or broke into 2 halves. The lag phase was markedly dependent on the weight ratios of EC/SDL or EC/HPMC in the outer shell. Different time lags of the press-coated tablets from 1.0 to 16.3 hours could be modulated by changing the type and amount of the excipients. A semilogarithmic plot of the time lag of the tablet against the weight ratios of EC/SDL or EC/HPMC in the outer shell demonstrated a good linear relationship, with r = 0.976 and r = 0.982, respectively. The predetermined time lag prior to the drug release from a press-coated tablet prepared by using a micronized EC as a retarding coating shell can be adequately scheduled with the addition of hydrophilic excipients according to the time or site requirements.

Diagenetic patterns and pore space distribution along a platform to outer-shelf transect (Urgonian limestone, Barremian-Aptian, SE France)

NASA Astrophysics Data System (ADS)

Léonide, Philippe; Fournier, François; Reijmer, John J. G.; Vonhof, Hubert; Borgomano, Jean; Dijk, Jurrien; Rosenthal, Maelle; van Goethem, Manon; Cochard, Jean; Meulenaars, Karlien

2014-06-01

The Urgonian limestones of Late Barremian/Early Aptian from Provence (SE, France) are characterized by the occurrence of microporous limestones at regional scale alternating with tight carbonates. This study, based on petrographical (sediment texture, facies) and diagenetical analyses (cement stratigraphy, porosity and isotope geochemistry) of more than 800 limestone samples provides insight into the parameters controlling the genesis, preservation or occlusion of microporosity along an inner platform to outer shelf transect. The tight and microporous Urgonian limestones from Provence can be grouped into 5 rock-types based on textures, associated depositional environments, porosity and pore-type, being: (1) tight inner-platform: TIP; (2) porous inner platform: PIP; (3) tight outer platform: TOP; (4) porous outer platform: POP and (5) tight outer shelf: TOS. In tight (TIP, TOP and TOS types) limestones intergranular and intragranular pore spaces were entirely occluded by early marine and/or early meteoric cementation, whereas in microporous (PIP, POP) limestones a significant fraction of the intergranular macroporosity was preserved during early and shallow burial diagenesis. Micrite neomorphism (hybrid Ostwald ripening process) occurred during meteoric shallow burial diagenesis in PIP and POP limestones during the regional Durancian Uplift event (Albian-Lower Cenomanian). This process resulted in microporosity enhancement and preservation. Circulation of meteoric fluids during exhumation produces intercrystalline microporosity enhancement and moldic porosity development. The present study documents the important role that both early diagenetic and depositional cycles and long-term tectonic processes have on pore space evolution and distribution in Mesozoic platform carbonates.

Photoreceptor change and visual outcome after idiopathic epiretinal membrane removal with or without additional internal limiting membrane peeling.

PubMed

Ahn, Seong Joon; Ahn, Jeeyun; Woo, Se Joon; Park, Kyu Hyung

2014-01-01

To compare the postoperative photoreceptor status and visual outcome after epiretinal membrane removal with or without additional internal limiting membrane (ILM) peeling. Medical records of 40 eyes from 37 patients undergoing epiretinal membrane removal with residual ILM peeling (additional ILM peeling group) and 69 eyes from 65 patients undergoing epiretinal membrane removal without additional ILM peeling (no additional peeling group) were reviewed. The length of defects in cone outer segment tips, inner segment/outer segment junction, and external limiting membrane line were measured using spectral domain optical coherence tomography images of the fovea before and at 1, 3, 6, and 12 months after the surgery. Cone outer segment tips and inner segment/outer segment junction line defects were most severe at postoperative 1 month and gradually restored at 12 months postoperatively. The cone outer segment tips line defect in the additional ILM peeling group was significantly greater than that in the no additional peeling group at postoperative 1 month (P = 0.006), and best-corrected visual acuity was significantly worse in the former group at the same month (P = 0.001). There was no significant difference in the defect size and best-corrected visual acuity at subsequent visits and recurrence rates between the two groups. Patients who received epiretinal membrane surgery without additional ILM peeling showed better visual and anatomical outcome than those with additional ILM peeling at postoperative 1 month. However, surgical outcomes were comparable between the two groups, thereafter. In terms of visual outcome and photoreceptor integrity, additional ILM peeling may not be an essential procedure.

Low-pressure water-cooled inductively coupled plasma torch

DOEpatents

Seliskar, C.J.; Warner, D.K.

1984-02-16

An inductively coupled plasma torch is provided which comprises an inner tube, including a sample injection port to which the sample to be tested is supplied and comprising an enlarged central portion in which the plasma flame is confined; an outer tube surrounding the inner tube and containing water therein for cooling the inner tube, the outer tube including a water inlet port to which water is supplied and a water outlet port spaced from the water inlet port and from which water is removed after flowing through the outer tube; and an rf induction coil for inducing the plasma in the gas passing into the tube through the sample injection port. The sample injection port comprises a capillary tube including a reduced diameter orifice, projecting into the lower end of the inner tube. The water inlet is located at the lower end of the outer tube and the rf heating coil is disposed around the outer tube above and adjacent to the water inlet.

Apparatus for premixing in a gas turbine engine

DOEpatents

McCormick, Keith Alan; Smith, Duane A.

2002-01-01

An apparatus for mixing fuel with oxidizing agent is disclosed comprising an outer body and an inner body. The outer body has an interior surface extending between an inlet end toward an outlet end. The interior surface includes a first plurality of openings. The inner body has an exterior surface extending between the first end and the second end of the inner body. The exterior surface of the inner body includes a second plurality of openings. At least a portion of the exterior surface of the inner body is positioned within the outer body to define a mixing channel between the exterior surface of the inner body and the interior surface of the outer body. In one form the first and second plurality of openings substantially longitudinally span at least one of the outer body and the inner body. In another form the first and second plurality of openings are substantially radially oriented. In yet another form the first and second plurality of openings are offset from one another.

Distance Measurement on an Endogenous Membrane Transporter in E. coli Cells and Native Membranes Using EPR Spectroscopy.

PubMed

Joseph, Benesh; Sikora, Arthur; Bordignon, Enrica; Jeschke, Gunnar; Cafiso, David S; Prisner, Thomas F

2015-05-18

Membrane proteins may be influenced by the environment, and they may be unstable in detergents or fail to crystallize. As a result, approaches to characterize structures in a native environment are highly desirable. Here, we report a novel general strategy for precise distance measurements on outer membrane proteins in whole Escherichia coli cells and isolated outer membranes. The cobalamin transporter BtuB was overexpressed and spin-labeled in whole cells and outer membranes and interspin distances were measured to a spin-labeled cobalamin using pulse EPR spectroscopy. A comparative analysis of the data reveals a similar interspin distance between whole cells, outer membranes, and synthetic vesicles. This approach provides an elegant way to study conformational changes or protein-protein/ligand interactions at surface-exposed sites of membrane protein complexes in whole cells and native membranes, and provides a method to validate outer membrane protein structures in their native environment. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Localization of cytochromes in the outer membrane of Desulfovibrio vulgaris (Hildenborough) and their role in anaerobic biocorrosion.

PubMed

Van Ommen Kloeke, F; Bryant, R D; Laishley, E J

1995-12-01

A protocol was developed whereby the outer and cytoplasmic membranes of the sulfate-reducing bacterium Desulfovibrio vulgaris (Hildenborough) were isolated and partially characterized. The isolated outer membrane fractions from cultures grown under high (100 ppm) and low (5 ppm) Fe2+ conditions were compared by SDS-PAGE electrophoresis, and showed that several protein bands were derepressed under the low iron conditions, most notably at 50 kDa, and 77.5 kDa. Outer membrane isolated from low iron cultured cells was found to contain two proteins, 77.5 kDa and 62.5 kDa in size, that reacted with a heme-specific stain and were referred to as high molecular weight cytochromes. Studies conducted on the low iron isolated outer membrane by a phosphate/mild steel hydrogen evolution system showed that addition of the membrane fraction caused an immediate acceleration in H2 production. A new model for the anaerobic biocorrosion of mild steel is proposed.

Low-pressure water-cooled inductively coupled plasma torch

DOEpatents

Seliskar, Carl J.; Warner, David K.

1988-12-27

An inductively coupled plasma torch is provided which comprises an inner tube, including a sample injection port to which the sample to be tested is supplied and comprising an enlarged central portion in which the plasma flame is confined; an outer tube surrounding the inner tube and containing water therein for cooling the inner tube, the outer tube including a water inlet port to which water is supplied and a water outlet port spaced from the water inlet port and from which water is removed after flowing through the outer tube; and an r.f. induction coil for inducing the plasma in the gas passing into the tube through the sample injection port. The sample injection port comprises a capillary tube including a reduced diameter orifice, projecting into the lower end of the inner tube. The water inlet is located at the lower end of the outer tube and the r.f. heating coil is disposed around the outer tube above and adjacent to the water inlet.

The spanwise spectra in wall-bounded turbulence

NASA Astrophysics Data System (ADS)

Wang, Hong-Ping; Wang, Shi-Zhao; He, Guo-Wei

2017-12-01

The pre-multiplied spanwise energy spectra of streamwise velocity fluctuations are investigated in this paper. Two distinct spectral peaks in the spanwise spectra are observed in low-Reynolds-number wall-bounded turbulence. The spectra are calculated from direct numerical simulation (DNS) of turbulent channel flows and zero-pressure-gradient boundary layer flows. These two peaks locate in the near-wall and outer regions and are referred to as the inner peak and the outer peak, respectively. This result implies that the streamwise velocity fluctuations can be separated into large and small scales in the spanwise direction even though the friction Reynolds number Re_τ can be as low as 1000. The properties of the inner and outer peaks in the spanwise spectra are analyzed. The locations of the inner peak are invariant over a range of Reynolds numbers. However, the locations of the outer peak are associated with the Reynolds number, which are much higher than those of the outer peak of the pre-multiplied streamwise energy spectra of the streamwise velocity.

Apparatus and methods for installing, removing and adjusting an inner turbine shell section relative to an outer turbine shell section

DOEpatents

Leach, David; Bergendahl, Peter Allen; Waldo, Stuart Forrest; Smith, Robert Leroy; Phelps, Robert Kim

2001-01-01

A turbine includes upper and lower inner shell sections mounting the nozzles and shrouds and which inner shell is supported by pins secured to a surrounding outer shell. To disassemble the turbine for access to the inner shell sections and rotor, an alignment fixture is secured to the lower outer shell section and has pins engaging the inner shell section. To disassemble the turbine, the inner shell weight is transferred to the lower outer shell section via the alignment fixture and cradle pins. Roller assemblies are inserted through access openings vacated by support pins to permit rotation of the lower inner shell section out of and into the lower outer shell section during disassembly and assembly. The alignment fixture includes adjusting rods for adjusting the inner shell axially, vertically, laterally and about a lateral axis. A roller over-cage is provided to rotate the inner shell and a dummy shell to facilitate assembly and disassembly in the field.

Ultra-Wide-Field Fundus Autofluorescence and Spectral-Domain Optical Coherence Tomography Findings in Syphilitic Outer Retinitis.

PubMed

Saleh, Mohamed G A; Campbell, John Peter; Yang, Paul; Lin, Phoebe

2017-03-01

To determine the ultra-wide-field fundus autofluorescence (UWFFAF) and optical coherence tomography (OCT) features of syphilitic outer retinopathy (SOR). Retrospective chart review. Three patients with SOR were investigated. Treatment with parenteral penicillin led to improvement of outer retinopathy, visual acuity, and symptoms. UWFFAF showed speckled hyperautofluorescence, hypoautofluorescence, and normal autofluorescence, similar to what has been described as a trizonal pattern in acute zonal occult outer retinopathy (AZOOR) in the chronic case of SOR, but with hyperautofluorescent areas in the two acute cases. OCT showed disruption of the photoreceptor outer segment ellipsoid zone and external limiting membrane, which improved after penicillin treatment, and corresponded to normalization of the hyperautofluorescent areas on UWFFAF. There was irregularity and nodular thickening of retinal pigment epithelium on OCT in areas of mottled hyperautofluorescence. SOR can present similarly to AZOOR on UWFFAF and should be highly suspected in cases presenting like AZOOR. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:208-215. ]. Copyright 2017, SLACK Incorporated.

The spanwise spectra in wall-bounded turbulence

NASA Astrophysics Data System (ADS)

Wang, Hong-Ping; Wang, Shi-Zhao; He, Guo-Wei

2018-06-01

The pre-multiplied spanwise energy spectra of streamwise velocity fluctuations are investigated in this paper. Two distinct spectral peaks in the spanwise spectra are observed in low-Reynolds-number wall-bounded turbulence. The spectra are calculated from direct numerical simulation (DNS) of turbulent channel flows and zero-pressure-gradient boundary layer flows. These two peaks locate in the near-wall and outer regions and are referred to as the inner peak and the outer peak, respectively. This result implies that the streamwise velocity fluctuations can be separated into large and small scales in the spanwise direction even though the friction Reynolds number Re_τ can be as low as 1000. The properties of the inner and outer peaks in the spanwise spectra are analyzed. The locations of the inner peak are invariant over a range of Reynolds numbers. However, the locations of the outer peak are associated with the Reynolds number, which are much higher than those of the outer peak of the pre-multiplied streamwise energy spectra of the streamwise velocity.

Pole-phase modulated toroidal winding for an induction machine

DOEpatents

Miller, John Michael; Ostovic, Vlado

1999-11-02

A stator (10) for an induction machine for a vehicle has a cylindrical core (12) with inner and outer slots (26, 28) extending longitudinally along the inner and outer peripheries between the end faces (22, 24). Each outer slot is associated with several adjacent inner slots. A plurality of toroidal coils (14) are wound about the core and laid in the inner and outer slots. Each coil occupies a single inner slot and is laid in the associated outer slot thereby minimizing the distance the coil extends from the end faces and minimizing the length of the induction machine. The toroidal coils are configured for an arbitrary pole phase modulation wherein the coils are configured with variable numbers of phases and poles for providing maximum torque for cranking and switchable to a another phase and pole configuration for alternator operation. An adaptor ring (36) circumferentially positioned about the stator improves mechanical strength, and provides a coolant channel manifold (34) for removing heat produced in stator windings during operation.