High Resolution X-Ray Micro-CT of Ultra-Thin Wall Space Components

NASA Technical Reports Server (NTRS)

Roth, Don J.; Rauser, R. W.; Bowman, Randy R.; Bonacuse, Peter; Martin, Richard E.; Locci, I. E.; Kelley, M.

2012-01-01

A high resolution micro-CT system has been assembled and is being used to provide optimal characterization for ultra-thin wall space components. The Glenn Research Center NDE Sciences Team, using this CT system, has assumed the role of inspection vendor for the Advanced Stirling Convertor (ASC) project at NASA. This article will discuss many aspects of the development of the CT scanning for this type of component, including CT system overview; inspection requirements; process development, software utilized and developed to visualize, process, and analyze results; calibration sample development; results on actual samples; correlation with optical/SEM characterization; CT modeling; and development of automatic flaw recognition software. Keywords: Nondestructive Evaluation, NDE, Computed Tomography, Imaging, X-ray, Metallic Components, Thin Wall Inspection

Overview of paint removal methods

NASA Astrophysics Data System (ADS)

Foster, Terry

1995-04-01

With the introduction of strict environmental regulations governing the use and disposal of methylene chloride and phenols, major components of chemical paint strippers, there have been many new environmentally safe and effective methods of paint removal developed. The new methods developed for removing coatings from aircraft and aircraft components include: mechanical methods using abrasive media such as plastic, wheat starch, walnut shells, ice and dry ice, environmentally safe chemical strippers and paint softeners, and optical methods such as lasers and flash lamps. Each method has its advantages and disadvantages, and some have unique applications. For example, mechanical and abrasive methods can damage sensitive surfaces such as composite materials and strict control of blast parameters and conditions are required. Optical methods can be slow, leaving paint residues, and chemical methods may not remove all of the coating or require special coating formulations to be effective. As an introduction to environmentally safe and effective methods of paint removal, this paper is an overview of the various methods available. The purpose of this overview is to introduce the various paint removal methods available.

A structured overview of trends and technologies used in dynamic hand orthoses.

PubMed

Bos, Ronald A; Haarman, Claudia J W; Stortelder, Teun; Nizamis, Kostas; Herder, Just L; Stienen, Arno H A; Plettenburg, Dick H

2016-06-29

The development of dynamic hand orthoses is a fast-growing field of research and has resulted in many different devices. A large and diverse solution space is formed by the various mechatronic components which are used in these devices. They are the result of making complex design choices within the constraints imposed by the application, the environment and the patient's individual needs. Several review studies exist that cover the details of specific disciplines which play a part in the developmental cycle. However, a general collection of all endeavors around the world and a structured overview of the solution space which integrates these disciplines is missing. In this study, a total of 165 individual dynamic hand orthoses were collected and their mechatronic components were categorized into a framework with a signal, energy and mechanical domain. Its hierarchical structure allows it to reach out towards the different disciplines while connecting them with common properties. Additionally, available arguments behind design choices were collected and related to the trends in the solution space. As a result, a comprehensive overview of the used mechatronic components in dynamic hand orthoses is presented.

Overview of innovative next generation materials for security and defense applications

NASA Astrophysics Data System (ADS)

Taylor, Edward W.; Taylor, Linda R.

2008-10-01

A short technology Overview of recently reported research and development focusing on recent advances in polymer/organic and hybrid-nanotechnology based materials that offer resistance to ionizing and displacement radiations and perhaps which are suitable for transition to next-generation systems is presented. The Overview will focus on new and emerging material technology for the military, first responders, and space systems. Recent material research results and data as well as the potential for diverse applications of these materials to new component developments such as high speed EO polymer modulators and radiation shielding for protection of military and space assets will be discussed. In particular, the ability of several organic/polymer hybrids to self-heal when irradiated by gamma-rays is discussed.

2011 Workplace and Equal Opportunity Survey of Reserve Component Members: Overview Report

DTIC Science & Technology

2014-02-06

2011 Workplace and Equal Opportunity Survey of Reserve Members Overview Report The estimated cost of report or study for the Department of...Ask for report by ADA602626 February 26, 2014 OVERVIEW REPORT Note No. 2013-003 1 2011 Workplace and Equal Opportunity Survey of Reserve...harassment and discrimination within the Reserve components. This overview report discusses findings from the 2011 Workplace and Equal Opportunity

20 CFR 655.103 - Overview of this subpart and definition of terms.

Code of Federal Regulations, 2011 CFR

2011-04-01

... component of the ETA that provides national leadership and policy guidance and develops regulations and... Administrator's designee. Positive recruitment. The active participation of an employer or its authorized hiring...

Residential solar-heating/cooling system

NASA Technical Reports Server (NTRS)

1980-01-01

Report documents progress of residential solar-heating and cooling system development program at 5-month mark of anticipated 17-month program. System design has been completed, and development and component testing has been initiated. Report includes diagrams, operation overview, optimization studies of subcomponents, and marketing plans for system.

Teaching and Testing Early Reading. Focus On

ERIC Educational Resources Information Center

Mraz, Maryann; Kissel, Brian

2007-01-01

This issue of "Focus On" provides an overview of several key early literacy components: phonemic awareness, alphabet knowledge, concepts of print, oral language development, writing, family literacy, and reading aloud. Suggestions for assessing early literacy development are provided, and examples of implementation of effective early literacy…

Polymer-based composites for aerospace: An overview of IMAST results

NASA Astrophysics Data System (ADS)

Milella, Eva; Cammarano, Aniello

2016-05-01

This paper gives an overview of technological results, achieved by IMAST, the Technological Cluster on Engineering of Polymeric Composite Materials and Structures, in the completed Research Projects in the aerospace field. In this sector, the Cluster developed different solutions: lightweight multifunctional fiber-reinforced polymer composites for aeronautic structures, advanced manufacturing processes (for the optimization of energy consumption and waste reduction) and multifunctional components (e.g., thermal, electrical, acoustic and fire resistance).

Compositional Specification of Software Architecture

NASA Technical Reports Server (NTRS)

Penix, John; Lau, Sonie (Technical Monitor)

1998-01-01

This paper describes our experience using parameterized algebraic specifications to model properties of software architectures. The goal is to model the decomposition of requirements independent of the style used to implement the architecture. We begin by providing an overview of the role of architecture specification in software development. We then describe how architecture specifications are build up from component and connector specifications and give an overview of insights gained from a case study used to validate the method.

Sizing Power Components of an Electrically Driven Tail Cone Thruster and a Range Extender

NASA Technical Reports Server (NTRS)

Jansen, Ralph H.; Bowman, Cheryl; Jankovsky, Amy

2016-01-01

The aeronautics industry has been challenged on many fronts to increase efficiency, reduce emissions, and decrease dependency on carbon-based fuels. This paper provides an overview of the turboelectric and hybrid electric technologies being developed under NASA's Advanced Air Transportation Technology (AATT) Project and discusses how these technologies can impact vehicle design. The discussion includes an overview of key hybrid electric studies and technology investments, the approach to making informed investment decisions based on key performance parameters and mission studies, and the power system architectures for two candidate aircraft. Finally, the power components for a single-aisle turboelectric aircraft with an electrically driven tail cone thruster and for a hybrid-electric nine-passenger aircraft with a range extender are parametrically sized, and the sensitivity of these components to key parameters is presented.

NASA Glenn Research Center Electrochemistry Branch Battery Overview

NASA Technical Reports Server (NTRS)

Manzo, Michelle A.

2010-01-01

This presentation covers an overview of NASA Glenn s history and heritage in the development of electrochemical systems for aerospace applications. Specific areas of focus are Li-ion batteries and their development for future Exploration missions. Current component development efforts for high energy and ultra high energy Li-ion batteries are addressed. Electrochemical systems are critical to the success of Exploration, Science and Space Operations missions. NASA Glenn has a long, successful heritage with batteries and fuel cells for aerospace applications. GRC Battery capabilities and expertise span basic research through flight hardware development and implementation. There is a great deal of synergy between energy storage system needs for aerospace and terrestrial applications.

The Benefits of Peer Leader Programs: An Overview from the Literature

ERIC Educational Resources Information Center

Shook, Jaime L.; Keup, Jennifer R.

2012-01-01

The powerful influence of peers in human development has been widely documented, particularly within education. Throughout the history of higher education, peer interactions have been a component of scholarly explorations of student types, campus cultures, and even the cycle of student "generations." In addition, most student development theories…

The Unified Plant Growth Model (UPGM): software framework overview and model application

USDA-ARS?s Scientific Manuscript database

Since the Environmental Policy Integrated Climate (EPIC) model was developed in 1989, the EPIC plant growth component has been incorporated into other erosion and crop management models (e.g., WEPS, WEPP, SWAT, ALMANAC, and APEX) and modified to meet model developer research objectives. This has re...

Knowledge Management ERP Curriculum Design/Mapping (Theory and Development Tools)

ERIC Educational Resources Information Center

Swanson, Zane; Hepner, Michelle

2011-01-01

This study proposes a knowledge management framework for developing and managing enterprise resource planning (ERP) curriculum within business schools. Both theory and a practical implementation are addressed. The knowledge management (KM) framework has two components which utilize ERP from a big picture curriculum overview and a ground level…

A compendium of solar dish/Stirling technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stine, W.B.; Diver, R.B.

1994-01-01

This report surveys the emerging dish/Stirling technology. It documents -- using consistent terminology the design characteristics of dish concentrators, receivers, and Stirling engines applicable to solar electric power generation. Development status and operating experience for each system and an overview of dish/Stirling technology are also presented. This report enables comparisons of concentrator, receiver, and engine technologies. Specifications and performance data are presented on systems and on components that are in use or that could be used in dish/Stirling systems. This report is organized into two parts: The first part (Chapters 1 through 4) provides an overview of dish/Stirling technology --more » the dish/ Stirling components (concentrator, receiver, and engine/alternator), current technology, basic theory, and technology development. The second part (Chapters 5 through 7) provides a detailed survey of the existing dish/Stirling concentrators, receivers, and engine/alternators.« less

Overview of the National Aeronautics and Space Administration's Nondestructive Evaluation (NDE) Program

NASA Technical Reports Server (NTRS)

Generazio, Edward R.

2002-01-01

NASA's Office of Safety and Mission Assurance sponsors an Agency-wide NDE Program that supports Aeronautics and Space Transportation Technology, Human Exploration and Development of Space, Earth Science, and Space Science Enterprises. For each of these Enterprises, safety is the number one priority. Development of the next generation aero-space launch and transportation vehicles, satellites, and deep space probes have highlighted the enabling role that NDE plays in these advanced technology systems. Specific areas of advanced component development, component integrity, and structural heath management are critically supported by NDE technologies. The simultaneous goals of assuring safety, maintaining overall operational efficiency, and developing and utilizing revolutionary technologies to expand human activity and space-based commerce in the frontiers of air and space places increasing demands on the Agencies NDE infrastructure and resources. In this presentation, an overview of NASA's NDE Program will be presented, that includes a background and status of current Enterprise NDE issues, and the NDE investment areas being developed to meet Enterprise safety and mission assurance needs through the year 2009 and beyond.

Modeling of NASA's 30/20 GHz satellite communications system

NASA Technical Reports Server (NTRS)

Kwatra, S. C.; Maples, B. W.; Stevens, G. A.

1984-01-01

NASA is in the process of developing technology for a 30/20 GHz satellite communications link. Currently hardware is being assembled for a test transponder. A simulation package is being developed to study the link performance in the presence of interference and noise. This requires developing models for the components of the system. This paper describes techniques used to model the components for which data is available. Results of experiments performed using these models are described. A brief overview of NASA's 30/20 GHz communications satellite program is also included.

Demonstrating Robotic Autonomy in NASA's Intelligent Systems Project

NASA Technical Reports Server (NTRS)

Morris, Robert; Smith, Ben; Estlin, Tara; Pedersen, Liam

2004-01-01

This paper will provide an overview of NASA's investments in autonomy during the past five years within the Intelligent Systems Project, with particular attention paid to investments that have resulted in mission infusion of autonomy technology, in particular, into the recent Mars Exploration Rover (MER) mission. The content of the paper will be divided into two primary topic areas: a technical overview of the component technologies developed under the program, and a programmatic overview of the history and organization of the NASA IS project itself, with a focus on describing the program elements related to autonomy and intelligent robotics. The paper will also provide an overview of the September 2004 autonomy demonstrations, including a discussion of objectives, organization, and preliminary results (to the extent they are available before the submission deadline).

Overview of NASA/OAST efforts related to manufacturing technology

NASA Technical Reports Server (NTRS)

Saunders, N. T.

1976-01-01

Activities of the Office of Aeronautics and Space Technology (OAST) in a number of areas related to manufacturing technology are considered. In the computer-aided design area improved approaches are developed for the design of specific classes of components or structural subsystems. A generalized approach for the design of a complete aerospace vehicle is also developed. Efforts directed toward an increased use of composite materials in aerospace structures are also discussed and attention is given to projects concerned with the manufacture of turbine engine components.

EVA Training and Development Facilities

NASA Technical Reports Server (NTRS)

Cupples, Scott

2016-01-01

Overview: Vast majority of US EVA (ExtraVehicular Activity) training and EVA hardware development occurs at JSC; EVA training facilities used to develop and refine procedures and improve skills; EVA hardware development facilities test hardware to evaluate performance and certify requirement compliance; Environmental chambers enable testing of hardware from as large as suits to as small as individual components in thermal vacuum conditions.

Component-based integration of chemistry and optimization software.

PubMed

Kenny, Joseph P; Benson, Steven J; Alexeev, Yuri; Sarich, Jason; Janssen, Curtis L; McInnes, Lois Curfman; Krishnan, Manojkumar; Nieplocha, Jarek; Jurrus, Elizabeth; Fahlstrom, Carl; Windus, Theresa L

2004-11-15

Typical scientific software designs make rigid assumptions regarding programming language and data structures, frustrating software interoperability and scientific collaboration. Component-based software engineering is an emerging approach to managing the increasing complexity of scientific software. Component technology facilitates code interoperability and reuse. Through the adoption of methodology and tools developed by the Common Component Architecture Forum, we have developed a component architecture for molecular structure optimization. Using the NWChem and Massively Parallel Quantum Chemistry packages, we have produced chemistry components that provide capacity for energy and energy derivative evaluation. We have constructed geometry optimization applications by integrating the Toolkit for Advanced Optimization, Portable Extensible Toolkit for Scientific Computation, and Global Arrays packages, which provide optimization and linear algebra capabilities. We present a brief overview of the component development process and a description of abstract interfaces for chemical optimizations. The components conforming to these abstract interfaces allow the construction of applications using different chemistry and mathematics packages interchangeably. Initial numerical results for the component software demonstrate good performance, and highlight potential research enabled by this platform.

Structures Technology for Future Aerospace Systems

NASA Technical Reports Server (NTRS)

Noor, Ahmed K.; Venneri, Samuel L.; Paul, Donald B.; Hopkins, Mark A.

2000-01-01

An overview of structures technology for future aerospace systems is given. Discussion focuses on developments in component technologies that will improve the vehicle performance, advance the technology exploitation process, and reduce system life-cycle costs. The component technologies described are smart materials and structures, multifunctional materials and structures, affordable composite structures, extreme environment structures, flexible load bearing structures, and computational methods and simulation-based design. The trends in each of the component technologies are discussed and the applicability of these technologies to future aerospace vehicles is described.

The second demographic transition: A concise overview of its development

PubMed Central

Lesthaeghe, Ron

2014-01-01

This article gives a concise overview of the theoretical development of the concept of the “second demographic transition” since it was coined in 1986, its components, and its applicability, first to European populations and subsequently also to non-European societies as well. Both the demographic and the societal contrasts between the first demographic transition (FDT) and the second demographic transition (SDT) are highlighted. Then, the major criticisms of the SDT theory are outlined, and these issues are discussed in the light of the most recent developments in Europe, the United States, the Far East, and Latin America. It turns out that three major SDT patterns have developed and that these evolutions are contingent on much older systems of kinship and family organization. PMID:25453112

Component technology for stirling power converters

NASA Technical Reports Server (NTRS)

Thieme, Lanny G.

1991-01-01

NASA Lewis Research Center has organized a component technology program as part of the efforts to develop Stirling converter technology for space power applications. The Stirling Space Power Program is part of the NASA High Capacity Power Project of the Civil Space Technology Initiative (CSTI). NASA Lewis is also providing technical management for the DOE/Sandia program to develop Stirling converters for solar terrestrial power producing electricity for the utility grid. The primary contractors for the space power and solar terrestrial programs develop component technologies directly related to their goals. This Lewis component technology effort, while coordinated with the main programs, aims at longer term issues, advanced technologies, and independent assessments. An overview of work on linear alternators, engine/alternator/load interactions and controls, heat exchangers, materials, life and reliability, and bearings is presented.

Timeline-Based Mission Operations Architecture: An Overview

NASA Technical Reports Server (NTRS)

Chung, Seung H.; Bindschadler, Duane L.

2012-01-01

Some of the challenges in developing a mission operations system and operating a mission can be traced back to the challenge of integrating a mission operations system from its many components and to the challenge of maintaining consistent and accountable information throughout the operations processes. An important contributing factor to both of these challenges is the file-centric nature of today's systems. In this paper, we provide an overview of these challenges and argue the need to move toward an information-centric mission operations system. We propose an information representation called Timeline as an approach to enable such a move, and we provide an overview of a Timeline-based Mission Operations System architecture.

Environmental effects monitoring at the Terra Nova offshore oil development (Newfoundland, Canada): Program design and overview

NASA Astrophysics Data System (ADS)

DeBlois, Elisabeth M.; Tracy, Ellen; Janes, G. Gregory; Crowley, Roger D.; Wells, Trudy A.; Williams, Urban P.; Paine, Michael D.; Mathieu, Anne; Kilgour, Bruce W.

2014-12-01

An environmental effects monitoring (EEM) program was developed by Suncor (formerly Petro-Canada) in 1997/98 to assess effects of the Terra Nova offshore oil and gas development on the receiving environment. The Terra Nova Field is located on the Grand Banks approximately 350 km southeast of Newfoundland (Canada), at approximately 100 m water depth. The EEM program was developed with guidance from experts in government, academia and elsewhere, and with input from the public. The EEM program proposed by Suncor was accepted by Canadian regulatory agencies and the program was implemented in 2000, 2001, 2002, 2004, 2006, 2008 and 2010, with pre-development sampling in 1997. The program continues to be implemented every two years. EEM includes an assessment of alterations in sediment quality through examination of changes in sediment chemistry, particle size, toxicity and benthic invertebrate community structure. A second component of the program examines potential effects on two species of commercial fishing interest: Iceland scallop (Chlamys islandica) and American plaice (Hippoglossoides platessoides). Chemical body burden for these two species is examined and taste tests are performed to assess the presence of taint in edible tissues. Effects on American plaice bioindicators are also examined. A final component of the program assesses potential effects of the Terra Nova development on water quality and examines water column chemistry, chlorophyll concentration and physical properties. The papers presented in this collection focus on effects of drill cuttings and drilling muds on the seafloor environment and, as such, report results on sediment quality and bioaccumulation of drilling mud components in Iceland scallop and American plaice. This paper provides information on drilling discharges, an overview of the physical oceanography at the Terra Nova Field, and an overview of the field program designed to assess environmental effects of drilling at Terra Nova.

Development Problems With Component Construction. Proceedings of Conference of the Building Research Institute, Division of Engineering and Industrial Research (Fall 1959).

ERIC Educational Resources Information Center

National Academy of Sciences - National Research Council, Washington, DC.

Publication of conference papers includes--(1) an overview of the ceiling system complex by a lighting manufacturer, (2) review of problems influencing the development of roofing systems, (3) description of cooperative research within the cement industry, and (4) description of joint research development of structural ceramic panels. Included…

EDSN - Edison Demonstration for SmallSat Networks: EDSN Overview

NASA Technical Reports Server (NTRS)

Westley Atkins, Deborah Maria; Chartres, James

2015-01-01

The EDSN overview provides information on the project's objectives, particular technologies being demonstrated, an overview of the structural components of the satellites, and the concept of operations.

Applications of AN OO Methodology and Case to a Daq System

NASA Astrophysics Data System (ADS)

Bee, C. P.; Eshghi, S.; Jones, R.; Kolos, S.; Magherini, C.; Maidantchik, C.; Mapelli, L.; Mornacchi, G.; Niculescu, M.; Patel, A.; Prigent, D.; Spiwoks, R.; Soloviev, I.; Caprini, M.; Duval, P. Y.; Etienne, F.; Ferrato, D.; Le van Suu, A.; Qian, Z.; Gaponenko, I.; Merzliakov, Y.; Ambrosini, G.; Ferrari, R.; Fumagalli, G.; Polesello, G.

The RD13 project has evaluated the use of the Object Oriented Information Engineering (OOIE) method during the development of several software components connected to the DAQ system. The method is supported by a sophisticated commercial CASE tool (Object Management Workbench) and programming environment (Kappa) which covers the full life-cycle of the software including model simulation, code generation and application deployment. This paper gives an overview of the method, CASE tool, DAQ components which have been developed and we relate our experiences with the method and tool, its integration into our development environment and the spiral lifecycle it supports.

Ohio's Career Continuum Program Director's Handbook.

ERIC Educational Resources Information Center

Ohio State Dept. of Education, Columbus.

Aimed at local program directors, the handbook provides fundamental information, procedures, and strategies regarding the implementation and development of career education programs, K-10, in Ohio. An overview provides information on the purposes, history, administration, and educational components of the Ohio Career Education Program. Chapters…

Plasma facing materials and components for future fusion devices—development, characterization and performance under fusion specific loading conditions

NASA Astrophysics Data System (ADS)

Linke, J.

2006-04-01

The plasma exposed components in existing and future fusion devices are strongly affected by the plasma material interaction processes. These mechanisms have a strong influence on the plasma performance; in addition they have major impact on the lifetime of the plasma facing armour and the joining interface between the plasma facing material (PFM) and the heat sink. Besides physical and chemical sputtering processes, high heat quasi-stationary fluxes during normal and intense thermal transients are of serious concern for the engineers who develop reliable wall components. In addition, the material and component degradation due to intense fluxes of energetic neutrons is another critical issue in D-T-burning fusion devices which requires extensive R&D. This paper presents an overview on the materials development and joining, the testing of PFMs and components, and the analysis of the neutron irradiation induced degradation.

Pratt and Whitney Overview and Advanced Health Management Program

NASA Technical Reports Server (NTRS)

Inabinett, Calvin

2008-01-01

Hardware Development Activity: Design and Test Custom Multi-layer Circuit Boards for use in the Fault Emulation Unit; Logic design performed using VHDL; Layout power system for lab hardware; Work lab issues with software developers and software testers; Interface with Engine Systems personnel with performance of Engine hardware components; Perform off nominal testing with new engine hardware.

Integrating Computer-Based Career Development into Your Career Planning Program.

ERIC Educational Resources Information Center

Campbell, Robert B.; Mack, Sharon E.

This paper focuses on the real and theoretical usefulness of a computer-based career development system in a career planning program, based on a 2-year pilot program evaluating the DISCOVER system. The system overview discusses components and contents of DISCOVER, and describes the 11 modules which assist users in learning about their values,…

An Overview of Aerospace Propulsion Research at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Reddy, D. R.

2007-01-01

NASA Glenn Research center is the recognized leader in aerospace propulsion research, advanced technology development and revolutionary system concepts committed to meeting the increasing demand for low noise, low emission, high performance, and light weight propulsion systems for affordable and safe aviation and space transportation needs. The technologies span a broad range of areas including air breathing, as well as rocket propulsion systems, for commercial and military aerospace applications and for space launch, as well as in-space propulsion applications. The scope of work includes fundamentals, components, processes, and system interactions. Technologies developed use both experimental and analytical approaches. The presentation provides an overview of the current research and technology development activities at NASA Glenn Research Center .

Signal transduction mechanisms in plants: an overview

NASA Technical Reports Server (NTRS)

Clark, G. B.; Thompson, G. Jr; Roux, S. J.

2001-01-01

This article provides an overview on recent advances in some of the basic signalling mechanisms that participate in a wide variety of stimulus-response pathways. The mechanisms include calcium-based signalling, G-protein-mediated-signalling and signalling involving inositol phospholipids, with discussion on the role of protein kinases and phosphatases interspersed. As a further defining feature, the article highlights recent exciting findings on three extracellular components that have not been given coverage in previous reviews of signal transduction in plants, extracellular calmodulin, extracellular ATP, and integrin-like receptors, all of which affect plant growth and development.

EINGEERING BULLETINS: AIDS TO THE DEVELOPMENT OF REMEDIAL ALTERNATIVES

EPA Science Inventory

An overview of activities of the Risk Reduction Engineering Laboratory in response to the Environmental Protection Agency`s Treatability Initiative are described and a summary of the information in the first ten Engineering Bulletins, which are a component of the initiative, is p...

Executive control systems in the engineering design environment. M.S. Thesis

NASA Technical Reports Server (NTRS)

Hurst, P. W.

1985-01-01

An executive control system (ECS) is a software structure for unifying various applications codes into a comprehensive system. It provides a library of applications, a uniform access method through a cental user interface, and a data management facility. A survey of twenty-four executive control systems designed to unify various CAD/CAE applications for use in diverse engineering design environments within government and industry was conducted. The goals of this research were to establish system requirements to survey state-of-the-art architectural design approaches, and to provide an overview of the historical evolution of these systems. Foundations for design are presented and include environmental settings, system requirements, major architectural components, and a system classification scheme based on knowledge of the supported engineering domain(s). An overview of the design approaches used in developing the major architectural components of an ECS is presented with examples taken from the surveyed systems. Attention is drawn to four major areas of ECS development: interdisciplinary usage; standardization; knowledge utilization; and computer science technology transfer.

Life prediction of turbine components: On-going studies at the NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Spera, D. A.; Grisaffe, S. J.

1973-01-01

An overview is presented of the many studies at NASA-Lewis that form the turbine component life prediction program. This program has three phases: (1) development of life prediction methods for major failure modes through materials studies, (2) evaluation and improvement of these methods through a variety of burner rig studies on simulated components in research engines and advanced rigs. These three phases form a cooperative, interdisciplinary program. A bibliography of Lewis publications on fatigue, oxidation and coatings, and turbine engine alloys is included.

A Component Approach to Collaborative Scientific Software Development: Tools and Techniques Utilized by the Quantum Chemistry Science Application Partnership

DOE PAGES

Kenny, Joseph P.; Janssen, Curtis L.; Gordon, Mark S.; ...

2008-01-01

Cutting-edge scientific computing software is complex, increasingly involving the coupling of multiple packages to combine advanced algorithms or simulations at multiple physical scales. Component-based software engineering (CBSE) has been advanced as a technique for managing this complexity, and complex component applications have been created in the quantum chemistry domain, as well as several other simulation areas, using the component model advocated by the Common Component Architecture (CCA) Forum. While programming models do indeed enable sound software engineering practices, the selection of programming model is just one building block in a comprehensive approach to large-scale collaborative development which must also addressmore » interface and data standardization, and language and package interoperability. We provide an overview of the development approach utilized within the Quantum Chemistry Science Application Partnership, identifying design challenges, describing the techniques which we have adopted to address these challenges and highlighting the advantages which the CCA approach offers for collaborative development.« less

An Overview of the Formation and Attitude Control System for the Terrestrial Planet Finder Formation Flying Interferometer

NASA Technical Reports Server (NTRS)

Scharf, Daniel P.; Hadaegh, Fred Y.; Rahman, Zahidul H.; Shields, Joel F.; Singh, Gurkipal; Wette, Matthew R.

2004-01-01

The Terrestrial Planet Finder formation flying Interferometer (TPF-I) will be a five-spacecraft, precision formation operating near the second Sun-Earth Lagrange point. As part of technology development for TPF-I, a formation and attitude control system (FACS) is being developed that achieves the precision and functionality needed for the TPF-I formation and that will be demonstrated in a distributed, real-time simulation environment. In this paper we present an overview of FACS and discuss in detail its formation estimation, guidance and control architectures and algorithms. Since FACS is currently being integrated into a high-fidelity simulation environment, component simulations demonstrating algorithm performance are presented.

An Overview of the Formation and Attitude Control System for the Terrestrial Planet Finder Formation Flying Interferometer

NASA Technical Reports Server (NTRS)

Scharf, Daniel P.; Hadaegh, Fred Y.; Rahman, Zahidul H.; Shields, Joel F.; Singh, Gurkipal

2004-01-01

The Terrestrial Planet Finder formation flying Interferometer (TPF-I) will be a five-spacecraft, precision formation operating near a Sun-Earth Lagrange point. As part of technology development for TPF-I, a formation and attitude control system (FACS) is being developed that achieves the precision and functionality associated with the TPF-I formation. This FACS will be demonstrated in a distributed, real-time simulation environment. In this paper we present an overview of the FACS and discuss in detail its constituent formation estimation, guidance and control architectures and algorithms. Since the FACS is currently being integrated into a high-fidelity simulation environment, component simulations demonstrating algorithm performance are presented.

Overview of SLS Aeroacoustic Environment Development

NASA Technical Reports Server (NTRS)

Steva, Thomas; Herron, Andrew

2017-01-01

The Space Launch System (SLS) ascent aeroacoustic environments provide the externally driven noise levels predicted for vehicle ascent during transonic and supersonic flight, and serve as an important input for component and secondary structure vibroacoustic design criteria. This aerodynamically induced noise is predominantly generated by unsteady flow within the local boundary layer due to free stream interaction with the outer mold line (OML). Additional sources are shear flow interactions, shocks, protuberance flows, and wake flows. This presentation provides an overview of the aeroacoustics discipline along with the SLS environment development process, including wind tunnel testing and general data reduction methods. The state of the discipline is also presented with a summary of aeroacoustic measurement and computational techniques currently on the horizon.

Yavapai College Integrated Master Plan.

ERIC Educational Resources Information Center

Yavapai Coll., Prescott, AZ.

This integrated master plan for Yavapai College (Arizona) includes the following six key components: (1) district services overview; (2) educational services plan; (3) human resources plan; (4) information technology services; (5) facilities plan; and (6) financial plan. The master plan was developed as a result of discussions and meetings with…

Spatial repellents and attractants as components of a "push-pull" management strategy

USDA-ARS?s Scientific Manuscript database

This presentation was an overview of research efforts being conducted by the Mosquito and Fly Research Unit (MFRU) of the United States Department of Agriculture (USDA), Center for Medical and Veterinary Entomology (CMAVE) located in Gainesville, Florida, to develop innovative population management...

Parametric Crowd Generation Software for MS&T Simulations and Training

DTIC Science & Technology

2007-02-20

3 Technology Overview 5 Dynemotion System Components 5 Dynemotion System Architecture 6 Dynemotion-Enabled NPC Brain Cycles 9 Dynemotion API...Contents 10 Development Project Background Information 11 Potential Application and Impact for the DoD 13 Project Objectives, Scope...Methodology 13 Benefits of the Project 13 Project Innovation 14 *l_essons Learned and Open Questions 14 Research and Development Challenges 16

Analysis of Place Value Instruction and Development in Pre-Kindergarten Mathematics

ERIC Educational Resources Information Center

McGuire, Patrick; Kinzie, Mable B.

2013-01-01

Development of two-digit place value understanding in the elementary grades has been the subject of some study; however, research at the pre-kindergarten (Pre-K) level is limited. This two-part paper begins by providing an overview of two-digit place value instruction in Pre-K and describes the component parts of a research-based math curriculum,…

Challenges of the Open Source Component Marketplace in the Industry

NASA Astrophysics Data System (ADS)

Ayala, Claudia; Hauge, Øyvind; Conradi, Reidar; Franch, Xavier; Li, Jingyue; Velle, Ketil Sandanger

The reuse of Open Source Software components available on the Internet is playing a major role in the development of Component Based Software Systems. Nevertheless, the special nature of the OSS marketplace has taken the “classical” concept of software reuse based on centralized repositories to a completely different arena based on massive reuse over Internet. In this paper we provide an overview of the actual state of the OSS marketplace, and report preliminary findings about how companies interact with this marketplace to reuse OSS components. Such data was gathered from interviews in software companies in Spain and Norway. Based on these results we identify some challenges aimed to improve the industrial reuse of OSS components.

Nano-sized structures for the detection of food components and contaminants.

PubMed

Dudak, Fahriye Ceyda; Bas, Deniz; Basaran-Akgul, Nese; Tamer, Ugur; Boyaci, Ismail Hakki

2011-06-01

New methods to identify trace amount of food components and/or contaminants (infectious pathogens and chemicals) rapidly, accurately, and with high sensitivity are in constant demand to prevent foodborne illnesses. Multipurpose biofunctionalized engineered nanomaterials are very promising for the detection of food components and contaminants. The unique optical and magnetic properties of the nanoscale materials are very useful in the analysis of food. The objectives of this review paper are to discuss the development of applications of nanoscale structures related to food industries and to provide an overview of available methods of detecting food components and contaminants with particular emphasis on the use of nanoparticles.

2017 Workplace and Gender Relations Survey of Reserve Component Members: Overview Report

DTIC Science & Technology

2018-04-30

2017 Workplace and Gender Relations Survey of Reserve Component Members DoD Overview Report Additional copies of this report may be...www.dtic.mil/dtic/order.html Ask for report by DTIC# OPA Report No. 2018-026 April 2018 2017 Workplace and Gender Relations Survey of...OPA) 4800 Mark Center Drive, Suite 06E22, Alexandria, VA 22350-4000 OPA 2017 Workplace and Gender Relations Survey of Reserve Component Members ii

Information Power Goes Online: Teaching Information Literacy to Distance Learners.

ERIC Educational Resources Information Center

Parise, Pierina

1998-01-01

Describes how a course, "Information Power," at Marylhurst University (Oregon) was developed into an online version. Presents an overview of Web access in distance learning. Discusses instructional delivery through the WebCT software program; specific components of the online Information Power class; measuring learning outcomes; and pros and cons…

Overview of FIREMEN program at Ames Research Center

NASA Technical Reports Server (NTRS)

Kourtides, D. A.

1978-01-01

The Ames Firemen Program is described. The key elements of the program include: (1) the development and evaluation of aircraft interior composite panels; (2) the thermochemical and flammability characterization of thermoset and thermoplastic resins; and (3) the evolution of fire resist aircraft seat components. The first two elements are presented.

An international overview of the recording and use of functional traits in dairy cattle breeding and management

USDA-ARS?s Scientific Manuscript database

An important component in the development of sustainable dairy production systems is the maintenance of cow health and functionality. Genetic selection has resulted in substantial increases in cow productivity over the past fifty years, but health and fertility are increasingly important determinant...

Contractor point of view for system development and test program

NASA Technical Reports Server (NTRS)

Koide, F. K.; Ringer, D. E.; Earl, C. E.

1981-01-01

Industry's practice of testing space qualified hardware is examined. An overview of the Global Positioning System (GPS) Test Program is discussed from the component level to the sub-system compatibility tests with the space vehicle and finally to the launch site tests, all related to the Rubidium clock.

Laboratory-directed research and development: FY 1996 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1997-05-01

This report summarizes the FY 1996 goals and accomplishments of Laboratory-Directed Research and Development (LDRD) projects. It gives an overview of the LDRD program, summarizes work done on individual research projects, and provides an index to the projects` principal investigators. Projects are grouped by their LDRD component: Individual Projects, Competency Development, and Program Development. Within each component, they are further divided into nine technical disciplines: (1) materials science, (2) engineering and base technologies, (3) plasmas, fluids, and particle beams, (4) chemistry, (5) mathematics and computational sciences, (6) atomic and molecular physics, (7) geoscience, space science, and astrophysics, (8) nuclear andmore » particle physics, and (9) biosciences.« less

Overview of Threats and Failure Models for Safety-Relevant Computer-Based Systems

NASA Technical Reports Server (NTRS)

Torres-Pomales, Wilfredo

2015-01-01

This document presents a high-level overview of the threats to safety-relevant computer-based systems, including (1) a description of the introduction and activation of physical and logical faults; (2) the propagation of their effects; and (3) function-level and component-level error and failure mode models. These models can be used in the definition of fault hypotheses (i.e., assumptions) for threat-risk mitigation strategies. This document is a contribution to a guide currently under development that is intended to provide a general technical foundation for designers and evaluators of safety-relevant systems.

Large-Scale Cryogenic Testing of Launch Vehicle Ground Systems at the Kennedy Space Center

NASA Technical Reports Server (NTRS)

Ernst, E. W.; Sass, J. P.; Lobemeyer, D. A.; Sojourner, S. J.; Hatfield, W. H.; Rewinkel, D. A.

2007-01-01

The development of a new launch vehicle to support NASA's future exploration plans requires significant redesign and upgrade of Kennedy Space Center's (KSC) launch pad and ground support equipment systems. In many cases, specialized test equipment and systems will be required to certify the function of the new system designs under simulated operational conditions, including propellant loading. This paper provides an overview of the cryogenic test infrastructure that is in place at KSC to conduct development and qualification testing that ranges from the component level to the integrated-system level. An overview of the major cryogenic test facilities will be provided, along with a detailed explanation of the technology focus area for each facility

The Sensor Test for Orion RelNav Risk Mitigation (STORRM) Development Test Objective

NASA Technical Reports Server (NTRS)

Christian, John A.; Hinkel, Heather; D'Souza, Christopher N.; Maguire, Sean; Patangan, Mogi

2011-01-01

The Sensor Test for Orion Relative-Navigation Risk Mitigation (STORRM) Development Test Objective (DTO) flew aboard the Space Shuttle Endeavour on STS-134 in May- June 2011, and was designed to characterize the performance of the flash LIDAR and docking camera being developed for the Orion Multi-Purpose Crew Vehicle. The flash LIDAR, called the Vision Navigation Sensor (VNS), will be the primary navigation instrument used by the Orion vehicle during rendezvous, proximity operations, and docking. The DC will be used by the Orion crew for piloting cues during docking. This paper provides an overview of the STORRM test objectives and the concept of operations. It continues with a description of STORRM's major hardware components, which include the VNS, docking camera, and supporting avionics. Next, an overview of crew and analyst training activities will describe how the STORRM team prepared for flight. Then an overview of in-flight data collection and analysis is presented. Key findings and results from this project are summarized. Finally, the paper concludes with lessons learned from the STORRM DTO.

caGrid 1.0: a Grid enterprise architecture for cancer research.

PubMed

Oster, Scott; Langella, Stephen; Hastings, Shannon; Ervin, David; Madduri, Ravi; Kurc, Tahsin; Siebenlist, Frank; Covitz, Peter; Shanbhag, Krishnakant; Foster, Ian; Saltz, Joel

2007-10-11

caGrid is the core Grid architecture of the NCI-sponsored cancer Biomedical Informatics Grid (caBIG) program. The current release, caGrid version 1.0, is developed as the production Grid software infrastructure of caBIG. Based on feedback from adopters of the previous version (caGrid 0.5), it has been significantly enhanced with new features and improvements to existing components. This paper presents an overview of caGrid 1.0, its main components, and enhancements over caGrid 0.5.

Photonic Integrated Circuits

NASA Technical Reports Server (NTRS)

Krainak, Michael; Merritt, Scott

2016-01-01

Integrated photonics generally is the integration of multiple lithographically defined photonic and electronic components and devices (e.g. lasers, detectors, waveguides passive structures, modulators, electronic control and optical interconnects) on a single platform with nanometer-scale feature sizes. The development of photonic integrated circuits permits size, weight, power and cost reductions for spacecraft microprocessors, optical communication, processor buses, advanced data processing, and integrated optic science instrument optical systems, subsystems and components. This is particularly critical for small spacecraft platforms. We will give an overview of some NASA applications for integrated photonics.

Laser materials processing of complex components: from reverse engineering via automated beam path generation to short process development cycles

NASA Astrophysics Data System (ADS)

Görgl, Richard; Brandstätter, Elmar

2017-01-01

The article presents an overview of what is possible nowadays in the field of laser materials processing. The state of the art in the complete process chain is shown, starting with the generation of a specific components CAD data and continuing with the automated motion path generation for the laser head carried by a CNC or robot system. Application examples from laser cladding and laser-based additive manufacturing are given.

Methadone Treatment: Overview and Bibliography.

ERIC Educational Resources Information Center

Greenfield, Lawrence; Tang, Beth Archibald

This overview focuses on methadone treatment. Briefly, it describes the clinical uses of methadone for substance abuse treatment, explores dosage guidelines, and discusses counseling components. This overview also reviews research data on the application of methadone treatment to special populations, such as pregnant women, polydrug users, and…

National Standards for Family and Consumer Sciences Education.

ERIC Educational Resources Information Center

National Association of State Administrators for Family and Consumer Sciences.

The document presents a new set of standards for family and consumer sciences (FACS) education. Section 1 is a three-chapter overview. Chapter 1 addresses the rationale for change and the FACS vision and mission. Chapter 2 describes the approach to develop the national standards, FACS format, and components of the standards. Chapter 3 provides…

Developing Student Interest: An Overview of the Research and Implications for Geoscience Education Research and Teaching Practice

ERIC Educational Resources Information Center

van der Hoeven Kraft, Katrien J.

2017-01-01

Interest is a complex interplay between affective and cognitive components that drive motivation. Over decades of work in the educational psychology community, a theoretical framework has emerged that explains this complex interplay. Interest is initially externally triggered (triggered situational interest), which, through support, can become…

Form versus Function: Using Technology to Develop Individualized Education Programs for Students with Disabilities

ERIC Educational Resources Information Center

Wilson, Gloria Lodato; Michaels, Craig A.; Margolis, Howard

2005-01-01

This article discusses the use of IEP software applications from the perspectives of form (i.e., legally correct documents) and function (i.e., educationally appropriate individualized programs). The article provides an overview of the basic components of two fairly comprehensive IEP software programs and discusses the general strengths and…

An Overview of Online Educational Delivery Applications.

ERIC Educational Resources Information Center

Marsh, George E., II; Price, Barrie Jo; McFadden, Anna C.

This paper is a report on the types of online delivery applications used in institutions of higher education (IHEs) to develop and implement World Wide Web-based courses. Many IHEs are grappling with ways to implement and manage online instruction by using local personnel and resources, purchasing some components of management, or outsourcing…

An Overview of Development of Higher Education Access in China

ERIC Educational Resources Information Center

Liu, Lisha

2012-01-01

As a crucial component of higher education system, the models of student admissions differ worldwide due to diverse historical, traditional, and cultural factors. This paper presents a documentary study which seeks to identify some key developmental milestones of access to higher education in China. The paper begins with an outline history of the…

The Role of Mentoring in the Development of Professional Psychologists.

ERIC Educational Resources Information Center

Harmon-Bowman, Mona; Elmore, Richard T., Jr.

This paper provides an overview of mentoring in psychology, and includes the components of teaching, modeling, guiding, sponsoring, and counseling. The contributions of mentors toward the professional success of men and women in business, medicine and education are discussed. The materials suggest a need for further research because the literature…

Improving component interoperability and reusability with the java connection framework (JCF): overview and application to the ages-w environmental model

USDA-ARS?s Scientific Manuscript database

Environmental modeling framework (EMF) design goals are multi-dimensional and often include many aspects of general software framework development. Many functional capabilities offered by current EMFs are closely related to interoperability and reuse aspects. For example, an EMF needs to support dev...

Domain specific software architectures: Command and control

NASA Technical Reports Server (NTRS)

Braun, Christine; Hatch, William; Ruegsegger, Theodore; Balzer, Bob; Feather, Martin; Goldman, Neil; Wile, Dave

1992-01-01

GTE is the Command and Control contractor for the Domain Specific Software Architectures program. The objective of this program is to develop and demonstrate an architecture-driven, component-based capability for the automated generation of command and control (C2) applications. Such a capability will significantly reduce the cost of C2 applications development and will lead to improved system quality and reliability through the use of proven architectures and components. A major focus of GTE's approach is the automated generation of application components in particular subdomains. Our initial work in this area has concentrated in the message handling subdomain; we have defined and prototyped an approach that can automate one of the most software-intensive parts of C2 systems development. This paper provides an overview of the GTE team's DSSA approach and then presents our work on automated support for message processing.

NASIS data base management system - IBM 360/370 OS MVT implementation. 2: Overviews

NASA Technical Reports Server (NTRS)

1973-01-01

The systems overviews of the NASA Aerospace Safety Information System (NASIS) are presented. The overviews are directed toward informing management of a system's capabilities and requirements. The intent of the overviews is to introduce the system features to interested individuals. Each overview contains a description of the component's activities and roles in the overall system. The description includes charts and diagrams and a discussion of the performance requirements and growth potential of the module.

1999 LDRD Laboratory Directed Research and Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rita Spencer; Kyle Wheeler

This is the FY 1999 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5)more » engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.« less

Laboratory Directed Research and Development FY 1998 Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

John Vigil; Kyle Wheeler

This is the FY 1998 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principle investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5)more » engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.« less

Laboratory directed research and development: FY 1997 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1998-05-01

This is the FY 1997 Progress Report for the Laboratory Directed Research and Development (LDRD) program at Los Alamos National Laboratory. It gives an overview of the LDRD program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic and molecular physics and plasmas, fluids, and particle beams, (5)more » engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.« less

Overview of Lightweight Structures for Rotorcraft Engines and Drivetrains

NASA Technical Reports Server (NTRS)

Roberts, Gary D.

2011-01-01

This is an overview presentation of research being performed in the Advanced Materials Task within the NASA Subsonic Rotary Wing Project. This research is focused on technology areas that address both national goals and project goals for advanced rotorcraft. Specific technology areas discussed are: (1) high temperature materials for advanced turbines in turboshaft engines; (2) polymer matrix composites for lightweight drive system components; (3) lightweight structure approaches for noise and vibration control; and (4) an advanced metal alloy for lighter weight bearings and more reliable mechanical components. An overview of the technology in each area is discussed, and recent accomplishments are presented.

Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework.

PubMed

Sekhon, Mandeep; Cartwright, Martin; Francis, Jill J

2017-01-26

It is increasingly acknowledged that 'acceptability' should be considered when designing, evaluating and implementing healthcare interventions. However, the published literature offers little guidance on how to define or assess acceptability. The purpose of this study was to develop a multi-construct theoretical framework of acceptability of healthcare interventions that can be applied to assess prospective (i.e. anticipated) and retrospective (i.e. experienced) acceptability from the perspective of intervention delivers and recipients. Two methods were used to select the component constructs of acceptability. 1) An overview of reviews was conducted to identify systematic reviews that claim to define, theorise or measure acceptability of healthcare interventions. 2) Principles of inductive and deductive reasoning were applied to theorise the concept of acceptability and develop a theoretical framework. Steps included (1) defining acceptability; (2) describing its properties and scope and (3) identifying component constructs and empirical indicators. From the 43 reviews included in the overview, none explicitly theorised or defined acceptability. Measures used to assess acceptability focused on behaviour (e.g. dropout rates) (23 reviews), affect (i.e. feelings) (5 reviews), cognition (i.e. perceptions) (7 reviews) or a combination of these (8 reviews). From the methods described above we propose a definition: Acceptability is a multi-faceted construct that reflects the extent to which people delivering or receiving a healthcare intervention consider it to be appropriate, based on anticipated or experienced cognitive and emotional responses to the intervention. The theoretical framework of acceptability (TFA) consists of seven component constructs: affective attitude, burden, perceived effectiveness, ethicality, intervention coherence, opportunity costs, and self-efficacy. Despite frequent claims that healthcare interventions have assessed acceptability, it is evident that acceptability research could be more robust. The proposed definition of acceptability and the TFA can inform assessment tools and evaluations of the acceptability of new or existing interventions.

Nourish and Nurture: World Food Programme Assistance for Early Childhood Education in India's Integrated Child Development Services. Education Sector Monograph No. 3.

ERIC Educational Resources Information Center

Siraj-Blatchford, Iram

Part of UNESCO's Action Research in Family and Early Childhood series, this monograph is based upon a technical report on the Early Childhood Education (ECE) component of the Integrated Child Development Services (ICDS) program in India. This document overviews the ICDS and how better use could be made of World Food Programme (WFP) food aid along…

Overview of PACS

NASA Astrophysics Data System (ADS)

Vanden Brink, John A.

1995-08-01

Development of the DICOM standard and incremental developments in workstation, network, compression, archiving, and digital x-ray technology have produced cost effective image communication possibilities for selected medical applications. The emerging markets include modality PACS, mini PACS, and teleradiology. Military and VA programs lead the way in the move to adopt PACS technology. Commercial markets for PACS components and PAC systems are at LR400 million growing to LR500 million in 1996.

Developing the Systems Engineering Experience Accelerator (SEEA) Prototype and Roadmap

DTIC Science & Technology

2013-12-31

information to be automatically presented without comment. 2.2.2 NEW FEATURES AND CAPABILITIES A number of new multiplayer capabilities were...2.4.1 OVERVIEW The EA game engine has two components: the runtime engine and the tools suite. The tools suite includes the Experience Development...the Learner. Figure 6: Experience Accelerator Logical Block Diagram The EARTE is a multiuser architecture for internet gaming . It has light

Ground Vehicle Condition Based Maintenance

DTIC Science & Technology

2010-10-04

Diagnostic Process Map 32 FMEAs Developed : • Diesel Engine • Transmission • Alternators Analysis : • Identify failure modes • Derive design factors and...S&T Initiatives  TARDEC P&D Process Map  Component Testing  ARL CBM Research  AMSAA SDC & Terrain Modeling UNCLASSIFIED 3 CBM+ Overview...UNCLASSIFIED 4 RCM and CBM are core processes for CBM+ System Development • Army Regulation 750-1, 20 Sep 2007, p. 79 - Reliability Centered Maintenance (RCM

Oral submucous fibrosis: an overview of the aetiology, pathogenesis, classification, and principles of management.

PubMed

Arakeri, Gururaj; Brennan, Peter A

2013-10-01

Oral submucous fibrosis (OSMF) is a complex, debilitating, and precancerous condition. Formerly confined to the Indian subcontinent, it is now often seen in the Asian populations of the United Kingdom, USA, and other developed countries, and is therefore a serious problem for global health. The well-known causative agent of the disease, areca-nut is now recognised as a group one carcinogen. We review and discuss all components of OSMF, including the terminology, presentation, aetiology, and pathogenesis, and provide a brief overview of its management. Copyright © 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Overview of the Design, Development, and Application of Nickel-hydrogen Batteries

NASA Technical Reports Server (NTRS)

Thaller, Lawrence H.; Zimmerman, Albert H.

2003-01-01

This document provides an overview of the design, development, and application of nickel-hydrogen (Ni-H2) battery technology for aerospace applications. It complements and updates the information presented in NASA RP-1314, NASA Handbook for Nickel- Hydrogen Batteries, published in 1993. Since that time, nickel-hydrogen batteries have become widely accepted for aerospace energy storage requirements and much more has been learned. The intent of this document is to capture some of that additional knowledge. This document addresses various aspects of nickel-hydrogen technology including the electrochemical reactions, cell component design, and selection considerations; overall cell and battery design considerations; charge control considerations; and manufacturing issues that have surfaced over the years that nickel-hydrogen battery technology has been the major energy storage technology for geosynchronous and low-Earth-orbiting satellites.

Manipulation of Bloch surface waves: from subwavelength focusing to nondiffracting beam

NASA Astrophysics Data System (ADS)

Kim, Myun-Sik; Herzig, Hans Peter

2018-01-01

We present a different type of electromagnetic surface wave than a surface plasmon polariton (SPP), called Bloch surface wave (BSW). BSWs are sustained by dielectric multilayers, and therefore they do not suffer from dissipation. Their propagation length is unbeatably long, e.g., over several millimeters. Thanks to this feature, larger integrations of 2D photonic chips are realizable. To do this, 2D optical components and corresponding techniques are necessary to manipulate in-plane propagation of surface waves. We overview recent progresses of the BSW research on manipulation techniques and developed components. Our study will provide a good guideline of the BSW components for users.

Main Quality Attributes of Monoclonal Antibodies and Effect of Cell Culture Components

PubMed

Torkashvand, Fatemeh; Vaziri, Behrouz

2017-05-01

The culture media optimization is an inevitable part of upstream process development in therapeutic monoclonal antibodies (mAbs) production. The quality by design (QbD) approach defines the assured quality of the final product through the development stage. An important step in QbD is determination of the main quality attributes. During the media optimization, some of the main quality attributes such as glycosylation pattern, charge variants, aggregates, and low-molecular-weight species, could be significantly altered. Here, we provide an overview of how cell culture medium components affects the main quality attributes of the mAbs. Knowing the relationship between the culture media components and the main quality attributes could be successfully utilized for a rational optimization of mammalian cell culture media for industrial mAbs production.

Seismic performance of non-structural components and contents in buildings: an overview of NZ research

NASA Astrophysics Data System (ADS)

Dhakal, Rajesh P.; Pourali, Atefeh; Tasligedik, Ali Sahin; Yeow, Trevor; Baird, Andrew; MacRae, Gregory; Pampanin, Stefano; Palermo, Alessandro

2016-03-01

This paper summarizes the research on non-structural elements and building contents being conducted at University of Canterbury in New Zealand. Since the 2010-2011 series of Canterbury earthquakes, in which damage to non-structural components and contents contributed heavily to downtime and overall financial loss, attention to seismic performance and design of non-structural components and contents in buildings has increased exponentially in NZ. This has resulted in an increased allocation of resources to research leading to development of more resilient non-structural systems in buildings that would incur substantially less damage and cause little downtime during earthquakes. In the last few years, NZ researchers have made important developments in understanding and improving the seismic performance of secondary building elements such as partitions, facades, ceilings and contents.

Biology of Blood

MedlinePlus

... switch to the Professional version Home Blood Disorders Biology of Blood Overview of Blood Resources In This ... Version. DOCTORS: Click here for the Professional Version Biology of Blood Overview of Blood Components of Blood ...

New Developments in Undergraduate Education in Public Health: Implications for Health Education and Health Promotion

ERIC Educational Resources Information Center

Barnes, Michael D.; Wykoff, Randy; King, Laura Rasar; Petersen, Donna J.

2012-01-01

The article provides an overview of efforts to improve public health and health education training and on the potential use of Critical Component Elements (CCEs) for undergraduate health education programs toward more consistent quality assurance across programs. Considered in the context of the Galway Consensus Conference, the authors discuss the…

Computational mechanics and physics at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

South, Jerry C., Jr.

1987-01-01

An overview is given of computational mechanics and physics at NASA Langley Research Center. Computational analysis is a major component and tool in many of Langley's diverse research disciplines, as well as in the interdisciplinary research. Examples are given for algorithm development and advanced applications in aerodynamics, transition to turbulence and turbulence simulation, hypersonics, structures, and interdisciplinary optimization.

Overview of EPA's Approach to Developing Prospective Case Studies Technical Workshop: Case Studies to Assess Potential Impacts of Hydraulic Fracturing on Drinking Water Resources

EPA Science Inventory

One component of the United States Environmental Protection Agency's (EPA) study of the potential impacts of hydraulic fracturing on drinking water resources is prospective case studies, which are being conducted to more fully understand and assess if and how site specific hydrau...

The Promises and Challenges of Teaching from an Intersectional Perspective: Core Components and Applied Strategies

ERIC Educational Resources Information Center

Jones, Susan R.; Wijeyesinghe, Charmaine L.

2011-01-01

This chapter explores how the framework of intersectionality can be used by faculty in course development and classroom teaching. An overview of intersectionality, highlighting core assumptions and tenets of the framework, is presented first. These assumptions and tenets are then applied to classroom dynamics and the practice of teaching in…

Empowering Adolescent Survivors of Sexual Abuse: Application of a Solution-Focused Ericksonian Counseling Group

ERIC Educational Resources Information Center

Kress, Victoria E.; Hoffman, Rachel M.

2008-01-01

This article describes a solution-focused and Ericksonian group counseling model that can be used with adolescent girls who have been sexually abused. An overview of the components of this approach is provided. A postintervention focus group provided additional results and ideas for the future development of the group counseling model.

Maryland State Department of Education School Food and Nutrition Service Design Manual.

ERIC Educational Resources Information Center

Maryland State Dept. of Education, Baltimore.

The purpose of this manual is to suggest strategies for identifying components that must be addressed to create and develop a successful food service and nutrition facility. It focuses on the process involved in creating such facilities, and it provides an overview of the planning phase, design and construction, and educational specifications.…

Recent Progress on Stretchable Electronic Devices with Intrinsically Stretchable Components.

PubMed

Trung, Tran Quang; Lee, Nae-Eung

2017-01-01

Stretchable electronic devices with intrinsically stretchable components have significant inherent advantages, including simple fabrication processes, a high integrity of the stacked layers, and low cost in comparison with stretchable electronic devices based on non-stretchable components. The research in this field has focused on developing new intrinsically stretchable components for conductors, semiconductors, and insulators. New methodologies and fabrication processes have been developed to fabricate stretchable devices with intrinsically stretchable components. The latest successful examples of stretchable conductors for applications in interconnections, electrodes, and piezoresistive devices are reviewed here. Stretchable conductors can be used for electrode or sensor applications depending on the electrical properties of the stretchable conductors under mechanical strain. A detailed overview of the recent progress in stretchable semiconductors, stretchable insulators, and other novel stretchable materials is also given, along with a discussion of the associated technological innovations and challenges. Stretchable electronic devices with intrinsically stretchable components such as field-effect transistors (FETs), photodetectors, light-emitting diodes (LEDs), electronic skins, and energy harvesters are also described and a new strategy for development of stretchable electronic devices is discussed. Conclusions and future prospects for the development of stretchable electronic devices with intrinsically stretchable components are discussed. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

caGrid 1.0: A Grid Enterprise Architecture for Cancer Research

PubMed Central

Oster, Scott; Langella, Stephen; Hastings, Shannon; Ervin, David; Madduri, Ravi; Kurc, Tahsin; Siebenlist, Frank; Covitz, Peter; Shanbhag, Krishnakant; Foster, Ian; Saltz, Joel

2007-01-01

caGrid is the core Grid architecture of the NCI-sponsored cancer Biomedical Informatics Grid (caBIGTM) program. The current release, caGrid version 1.0, is developed as the production Grid software infrastructure of caBIGTM. Based on feedback from adopters of the previous version (caGrid 0.5), it has been significantly enhanced with new features and improvements to existing components. This paper presents an overview of caGrid 1.0, its main components, and enhancements over caGrid 0.5. PMID:18693901

ARTEMIS: Ares Real Time Environments for Modeling, Integration, and Simulation

NASA Technical Reports Server (NTRS)

Hughes, Ryan; Walker, David

2009-01-01

This slide presentation reviews the use of ARTEMIS in the development and testing of the ARES launch vehicles. Ares Real Time Environment for Modeling, Simulation and Integration (ARTEMIS) is the real time simulation supporting Ares I hardware-in-the-loop (HWIL) testing. ARTEMIS accurately models all Ares/Orion/Ground subsystems which interact with Ares avionics components from pre-launch through orbit insertion The ARTEMIS System integration Lab, and the STIF architecture is reviewed. The functional components of ARTEMIS are outlined. An overview of the models and a block diagram is presented.

GERICOS: A Generic Framework for the Development of On-Board Software

NASA Astrophysics Data System (ADS)

Plasson, P.; Cuomo, C.; Gabriel, G.; Gauthier, N.; Gueguen, L.; Malac-Allain, L.

2016-08-01

This paper presents an overview of the GERICOS framework (GEneRIC Onboard Software), its architecture, its various layers and its future evolutions. The GERICOS framework, developed and qualified by LESIA, offers a set of generic, reusable and customizable software components for the rapid development of payload flight software. The GERICOS framework has a layered structure. The first layer (GERICOS::CORE) implements the concept of active objects and forms an abstraction layer over the top of real-time kernels. The second layer (GERICOS::BLOCKS) offers a set of reusable software components for building flight software based on generic solutions to recurrent functionalities. The third layer (GERICOS::DRIVERS) implements software drivers for several COTS IP cores of the LEON processor ecosystem.

An Overview of ARL’s Multimodal Signatures Database and Web Interface

DTIC Science & Technology

2007-12-01

ActiveX components, which hindered distribution due to license agreements and run-time license software to use such components. g. Proprietary...Overview The database consists of multimodal signature data files in the HDF5 format. Generally, each signature file contains all the ancillary...only contains information in the database, Web interface, and signature files that is releasable to the public. The Web interface consists of static

The embodiment of authentic leadership.

PubMed

Waite, Roberta; McKinney, Nicole; Smith-Glasgow, Mary Ellen; Meloy, Faye A

2014-01-01

Development of student leadership capacity and efficacy is critical to the nursing profession, and vital to this process is a strong foundation in critical thinking that includes a depth of understanding of self (i.e., authentic leadership development). This article will (a) present a theoretical overview of authentic leadership as compared with other popular leadership theories, (b) provide an overview of development/implementation of an authentic leadership course, the first in a series of six one-credit courses as an integral component of the Macy Undergraduate Leadership Fellows Program for upper-level nursing students, and (c) discuss related implications for nursing education. Findings from an investigator-developed quantitative pre-post survey and qualitative evaluation questions are provided. Student feedback regarding the comprehensive nature of the course was extremely positive and affirmed the value of introspection associated with authentic leadership in ongoing personal and professional development. Critical pedagogy and action-oriented learning strategies also proved beneficial to student engagement. Copyright © 2014 Elsevier Inc. All rights reserved.

Overview of the production of sintered SiC optics and optical sub-assemblies

NASA Astrophysics Data System (ADS)

Williams, S.; Deny, P.

2005-08-01

The following is an overview on sintered silicon carbide (SSiC) material properties and processing requirements for the manufacturing of components for advanced technology optical systems. The overview will compare SSiC material properties to typical materials used for optics and optical structures. In addition, it will review manufacturing processes required to produce optical components in detail by process step. The process overview will illustrate current manufacturing process and concepts to expand the process size capability. The overview will include information on the substantial capital equipment employed in the manufacturing of SSIC. This paper will also review common in-process inspection methodology and design rules. The design rules are used to improve production yield, minimize cost, and maximize the inherent benefits of SSiC for optical systems. Optimizing optical system designs for a SSiC manufacturing process will allow systems designers to utilize SSiC as a low risk, cost competitive, and fast cycle time technology for next generation optical systems.

Stimuli Responsive Ionogels for Sensing Applications—An Overview

PubMed Central

Kavanagh, Andrew; Byrne, Robert; Diamond, Dermot; Fraser, Kevin J.

2012-01-01

This overview aims to summarize the existing potential of “Ionogels” as a platform to develop stimuli responsive materials. Ionogels are a class of materials that contain an Ionic Liquid (IL) confined within a polymer matrix. Recently defined as “a solid interconnected network spreading throughout a liquid phase”, the ionogel therefore combines the properties of both its solid and liquid components. ILs are low melting salts that exist as liquids composed entirely of cations and anions at or around 100 °C. Important physical properties of these liquids such as viscosity, density, melting point and conductivity can be altered to suit a purpose by choice of the cation/anion. Here we provide an overview to highlight the literature thus far, detailing the encapsulation of IL and responsive materials within these polymeric structures. Exciting applications in the areas of optical and electrochemical sensing, solid state electrolytes and actuating materials shall be discussed. PMID:24957961

In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

PubMed Central

Helms, Hans C; Abbott, N Joan; Burek, Malgorzata; Cecchelli, Romeo; Couraud, Pierre-Olivier; Deli, Maria A; Förster, Carola; Galla, Hans J; Romero, Ignacio A; Shusta, Eric V; Stebbins, Matthew J; Vandenhaute, Elodie; Weksler, Babette

2016-01-01

The endothelial cells lining the brain capillaries separate the blood from the brain parenchyma. The endothelial monolayer of the brain capillaries serves both as a crucial interface for exchange of nutrients, gases, and metabolites between blood and brain, and as a barrier for neurotoxic components of plasma and xenobiotics. This “blood-brain barrier” function is a major hindrance for drug uptake into the brain parenchyma. Cell culture models, based on either primary cells or immortalized brain endothelial cell lines, have been developed, in order to facilitate in vitro studies of drug transport to the brain and studies of endothelial cell biology and pathophysiology. In this review, we aim to give an overview of established in vitro blood–brain barrier models with a focus on their validation regarding a set of well-established blood–brain barrier characteristics. As an ideal cell culture model of the blood–brain barrier is yet to be developed, we also aim to give an overview of the advantages and drawbacks of the different models described. PMID:26868179

Development of Electronics for Low-Temperature Space Missions

NASA Technical Reports Server (NTRS)

Patterson, Richard L.; Hammoud, Ahmad; Dickman, John E.; Gerber, Scott S.; Overton, Eric

2001-01-01

Electronic systems that are capable of operating at cryogenic temperatures will be needed for many future NASA space missions, including deep space probes and spacecraft for planetary surface exploration. In addition to being able to survive the harsh deep space environment, low-temperature electronics would help improve circuit performance, increase system efficiency, and reduce payload development and launch costs. Terrestrial applications where components and systems must operate in low-temperature environments include cryogenic instrumentation, superconducting magnetic energy storage, magnetic levitation transportation systems, and arctic exploration. An ongoing research and development project for the design, fabrication, and characterization of low-temperature electronics and supporting technologies at NASA Glenn Research Center focuses on efficient power systems capable of surviving in and exploiting the advantages of low-temperature environments. Supporting technologies include dielectric and insulating materials, semiconductor devices, passive power components, optoelectronic devices, and packaging and integration of the developed components into prototype flight hardware. An overview of the project is presented, including a description of the test facilities, a discussion of selected data from component testing, and a presentation of ongoing research activities being performed in collaboration with various organizations.

Overview of Materials Qualification Needs for Metal Additive Manufacturing

NASA Astrophysics Data System (ADS)

Seifi, Mohsen; Salem, Ayman; Beuth, Jack; Harrysson, Ola; Lewandowski, John J.

2016-03-01

This overview highlights some of the key aspects regarding materials qualification needs across the additive manufacturing (AM) spectrum. AM technology has experienced considerable publicity and growth in the past few years with many successful insertions for non-mission-critical applications. However, to meet the full potential that AM has to offer, especially for flight-critical components (e.g., rotating parts, fracture-critical parts, etc.), qualification and certification efforts are necessary. While development of qualification standards will address some of these needs, this overview outlines some of the other key areas that will need to be considered in the qualification path, including various process-, microstructure-, and fracture-modeling activities in addition to integrating these with lifing activities targeting specific components. Ongoing work in the Advanced Manufacturing and Mechanical Reliability Center at Case Western Reserve University is focusing on fracture and fatigue testing to rapidly assess critical mechanical properties of some titanium alloys before and after post-processing, in addition to conducting nondestructive testing/evaluation using micro-computerized tomography at General Electric. Process mapping studies are being conducted at Carnegie Mellon University while large area microstructure characterization and informatics (EBSD and BSE) analyses are being conducted at Materials Resources LLC to enable future integration of these efforts via an Integrated Computational Materials Engineering approach to AM. Possible future pathways for materials qualification are provided.

Overview of Basic Immunology for Clinical Investigators.

PubMed

Stephen, Bettzy; Hajjar, Joud

2017-01-01

Tumor exists as a complex network of structures with an ability to evolve and evade the host immune surveillance mechanism. The immune milieu which includes macrophages, dendritic cells, natural killer cells, neutrophils, mast cells, B cells, and T cells are found in the core, the invasive margin, or the adjacent stromal or lymphoid component of the tumor. The immune infiltrate is heterogeneous and varies within a patient and between patients of the same tumor histology. The location, density, functionality, and the cross talk between the immune cells in the tumor microenvironment influence the nature of immune response, prognosis, and treatment outcomes in cancer patients. Therefore, an understanding of the characteristics of the immune cells and their role in tumor immune surveillance is of paramount importance to identify immune targets and to develop novel immune therapeutics in the war against cancer. In this chapter, we provide an overview of the individual components of the human immune system and the translational relevance of predictive biomarkers.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pesaran, A.A.; Penney, T.R.; Czanderna, A.W.

The objectives of this document are to present an overview of the work accomplished to date on desiccant cooling to provide assessment of the state of the art of desiccant cooling technology in the field of desiccant material dehumidifier components, desiccant systems, and models. The report also discusses the factors that affect the widespread acceptance of desiccant cooling technology. This report is organized as follows. First, a basic description and historical overview of desiccant cooling technology is provided. Then, the recent research and development (R&D) program history (focusing on DOE`s funded efforts) is discussed. The status of the technology elementsmore » (materials, components, systems) is discussed in detail and a preliminary study on the energy impact of desiccant technology is presented. R&D needs for advancing the technology in the market are identified. The National Renewable Energy Laboratory`s unique desiccant test facilities and their typical outputs are described briefly. Finally, the results of a comprehensive literature search on desiccant cooling are presented in a bibliography. The bibliography contains approximately 900 citations on desiccant cooling.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pesaran, A.A.; Penney, T.R.; Czanderna, A.W.

The objectives of this document are to present an overview of the work accomplished to date on desiccant cooling to provide assessment of the state of the art of desiccant cooling technology in the field of desiccant material dehumidifier components, desiccant systems, and models. The report also discusses the factors that affect the widespread acceptance of desiccant cooling technology. This report is organized as follows. First, a basic description and historical overview of desiccant cooling technology is provided. Then, the recent research and development (R D) program history (focusing on DOE's funded efforts) is discussed. The status of the technologymore » elements (materials, components, systems) is discussed in detail and a preliminary study on the energy impact of desiccant technology is presented. R D needs for advancing the technology in the market are identified. The National Renewable Energy Laboratory's unique desiccant test facilities and their typical outputs are described briefly. Finally, the results of a comprehensive literature search on desiccant cooling are presented in a bibliography. The bibliography contains approximately 900 citations on desiccant cooling.« less

The Primary Care Behavioral Health (PCBH) Model: An Overview and Operational Definition.

PubMed

Reiter, Jeffrey T; Dobmeyer, Anne C; Hunter, Christopher L

2018-06-01

The Primary Care Behavioral Health (PCBH) model is a prominent approach to the integration of behavioral health services into primary care settings. Implementation of the PCBH model has grown over the past two decades, yet research and training efforts have been slowed by inconsistent terminology and lack of a concise, operationalized definition of the model and its key components. This article provides the first concise operationalized definition of the PCBH model, developed from examination of multiple published resources and consultation with nationally recognized PCBH model experts. The definition frames the model as a team-based approach to managing biopsychosocial issues that present in primary care, with the over-arching goal of improving primary care in general. The article provides a description of the key components and strategies used in the model, the rationale for those strategies, a brief comparison of this model to other integration approaches, a focused summary of PCBH model outcomes, and an overview of common challenges to implementing the model.

Evaluation of COTS Electronic Parts for Extreme Temperature Use in NASA Missions

NASA Technical Reports Server (NTRS)

Patterson, Richard L.; Hammoud, Ahmad; Elbuluk, Malik

2008-01-01

Electronic systems capable of extreme temperature operation are required for many future NASA space exploration missions where it is desirable to have smaller, lighter, and less expensive spacecraft and probes. Presently, spacecraft on-board electronics are maintained at about room temperature by use of thermal control systems. An Extreme Temperature Electronics Program at the NASA Glenn Research Center focuses on development of electronics suitable for space exploration missions. The effects of exposure to extreme temperatures and thermal cycling are being investigated for commercial-off-the-shelf components as well as for components specially developed for harsh environments. An overview of this program along with selected data is presented.

Overview of NASA/OAST efforts related to manufacturing technology

NASA Technical Reports Server (NTRS)

Saunders, N. T.

1976-01-01

An overview of some of NASA's current efforts related to manufacturing technology and some possible directions for the future are presented. The topics discussed are: computer-aided design, composite structures, and turbine engine components.

W-8 Acoustic Casing Treatment Test Overview

NASA Technical Reports Server (NTRS)

Bozak, Rick; Podboy, Gary; Dougherty, Robert

2017-01-01

During February 2017, aerodynamic and acoustic testing was performed on a scale-model high bypass ratio turbofan rotor, R4, in an internal flow component test facility. An overview of the testing completed is presented.

A "Global Eye" for Teaching and Learning in Higher Education: A Critical Policy Analysis of the OECD's AHELO Study

ERIC Educational Resources Information Center

Shahjahan, Riyad A.; Torres, Lisette E.

2013-01-01

This article provides an overview and critical policy analysis of the Organisation for Economic Cooperation and Development's (OECD) international Assessment of Higher Education Learning Outcomes (AHELO) project which is currently under way. It briefly describes the purpose, components and participants of the AHELO project. Informed by a…

Development of KSC program for investigating and generating field failure rates. Volume 1: Summary and overview

NASA Technical Reports Server (NTRS)

Bean, E. E.; Bloomquist, C. E.

1972-01-01

A summary of the KSC program for investigating the reliability aspects of the ground support activities is presented. An analysis of unsatisfactory condition reports (RC), and the generation of reliability assessment of components based on the URC are discussed along with the design considerations for attaining reliable real time hardware/software configurations.

The NASA/Industry Design Analysis Methods for Vibrations (DAMVIBS) Program - A government overview. [of rotorcraft technology development using finite element method

NASA Technical Reports Server (NTRS)

Kvaternik, Raymond G.

1992-01-01

An overview is presented of government contributions to the program called Design Analysis Methods for Vibrations (DAMV) which attempted to develop finite-element-based analyses of rotorcraft vibrations. NASA initiated the program with a finite-element modeling program for the CH-47D tandem-rotor helicopter. The DAMV program emphasized four areas including: airframe finite-element modeling, difficult components studies, coupled rotor-airframe vibrations, and airframe structural optimization. Key accomplishments of the program include industrywide standards for modeling metal and composite airframes, improved industrial designs for vibrations, and the identification of critical structural contributors to airframe vibratory responses. The program also demonstrated the value of incorporating secondary modeling details to improving correlation, and the findings provide the basis for an improved finite-element-based dynamics design-analysis capability.

NASA thrusts in high-speed aeropropulsion research and development: An overview

NASA Technical Reports Server (NTRS)

Ziemianski, Joseph A.

1990-01-01

NASA is conducting aeronautical research over a broad range of Mach numbers. In addition to the advanced conventional takeoff or landing (CTOL) propulsion research described elsewhere, NASA Lewis has intensified its efforts towards propulsion technology for selected high speed flight applications. In a companion program, NASA Langley has also accomplished significant research in supersonic combustion ramjet (SCRAM) propulsion. An unclassified review is presented of the propulsion research results that are applicable for supersonic to hypersonic vehicles. This overview not only provides a preview of the more detailed presentations which follow, it also presents a viewpoint on future research directions by calling attention to the unique cycles, components, and facilities involved in this expanding area of work.

Computational models for the analysis/design of hypersonic scramjet components. I - Combustor and nozzle models

NASA Technical Reports Server (NTRS)

Dash, S. M.; Sinha, N.; Wolf, D. E.; York, B. J.

1986-01-01

An overview of computational models developed for the complete, design-oriented analysis of a scramjet propulsion system is provided. The modular approach taken involves the use of different PNS models to analyze the individual propulsion system components. The external compression and internal inlet flowfields are analyzed by the SCRAMP and SCRINT components discussed in Part II of this paper. The combustor is analyzed by the SCORCH code which is based upon SPLITP PNS pressure-split methodology formulated by Dash and Sinha. The nozzle is analyzed by the SCHNOZ code which is based upon SCIPVIS PNS shock-capturing methodology formulated by Dash and Wolf. The current status of these models, previous developments leading to this status, and, progress towards future hybrid and 3D versions are discussed in this paper.

IUSThrust Vector Control (TVC) servo system

NASA Technical Reports Server (NTRS)

Conner, G. E.

1979-01-01

The IUS TVC SERVO SYSTEM which consists of four electrically redundant electromechanical actuators, four potentiometer assemblies, and two controllers to provide movable nozzle control on both IUS solid rocket motors is developed. An overview of the more severe IUS TVC servo system design requirements, the system and component designs, and test data acquired on a preliminary development unit is presented. Attention is focused on the unique methods of sensing movable nozzle position and providing for redundant position locks.

Automated support for system's engineering and operations - The development of new paradigms

NASA Technical Reports Server (NTRS)

Truszkowski, Walt; Hall, Gardiner A.; Jaworski, Allan; Zoch, David

1992-01-01

Technological developments in spacecraft ground operations are reviewed. The technological, operations-oriented, managerial, and economic factors driving the evolution of the Mission Operations Control Center (MOCC), and its predecessor the Operational Control Center are examined. The functional components of the various MOCC subsystems are outlined. A brief overview is given of the concepts behind the The Knowledge-Based Software Engineering Environment, the Generic Spacecraft Analysis Assistant, and the Knowledge From Pictures tool.

Overview of radiation effects research in photonics

NASA Astrophysics Data System (ADS)

Webb, Robert C.; Cohn, Lewis M.; Taylor, Edward W.; Greenwell, Roger A.

1995-05-01

A brief overview of ongoing radiation effects research in photonics is presented focusing on integrated optic and acousto-optic components. A short summary of radiation-induced effects in electro-optic modulators, detector arrays, and other photonic technologies is presented along with extensive references. The coordinated radiation effects studies among researchers within the Tri-Service Organizations and international experimental teams are beginning to demonstrate consistent measurements of radiation-induced effects in photonic components and confirming earlier reported data. This paper will present an overview of these coordinated investigations and focus on key research being conducted with the AFMC Phillips Laboratory, Naval Research Laboratory, Defence Nuclear Agency, NATO Nuclear Effects Task Group, and the Tri-Service Photonics Coordinating Committee.

Additive Manufacturing of Aerospace Propulsion Components

NASA Technical Reports Server (NTRS)

Misra, Ajay K.; Grady, Joseph E.; Carter, Robert

2015-01-01

The presentation will provide an overview of ongoing activities on additive manufacturing of aerospace propulsion components, which included rocket propulsion and gas turbine engines. Future opportunities on additive manufacturing of hybrid electric propulsion components will be discussed.

Overview of the Project Prometheus Program

NASA Technical Reports Server (NTRS)

Burdick, G. M.

2003-01-01

This presentation will give an overview of the Project Prometheus Program (PPP, formerly the Nuclear Systems Initiative, NSI) and the Jupiter Icy Moons Orbiter (JIMO) Project (a component of PPP), a mission to the three icy Galilean moons of Jupiter.

Progress toward the development of an aircraft icing analysis capability

NASA Technical Reports Server (NTRS)

Shaw, R. J.

1984-01-01

An overview of the NASA efforts to develop an aircraft icing analysis capability is presented. Discussions are included of the overall and long term objectives of the program as well as current capabilities and limitations of the various computer codes being developed. Descriptions are given of codes being developed to analyze two and three dimensional trajectories of water droplets, airfoil ice accretion, aerodynamic performance degradation of components and complete aircraft configurations, electrothermal deicer, and fluid freezing point depressant deicer. The need for bench mark and verification data to support the code development is also discussed.

An overview of the mathematical and statistical analysis component of RICIS

NASA Technical Reports Server (NTRS)

Hallum, Cecil R.

1987-01-01

Mathematical and statistical analysis components of RICIS (Research Institute for Computing and Information Systems) can be used in the following problem areas: (1) quantification and measurement of software reliability; (2) assessment of changes in software reliability over time (reliability growth); (3) analysis of software-failure data; and (4) decision logic for whether to continue or stop testing software. Other areas of interest to NASA/JSC where mathematical and statistical analysis can be successfully employed include: math modeling of physical systems, simulation, statistical data reduction, evaluation methods, optimization, algorithm development, and mathematical methods in signal processing.

Aviation System Analysis Capability Executive Assistant Development

NASA Technical Reports Server (NTRS)

Roberts, Eileen; Villani, James A.; Anderson, Kevin; Book, Paul

1999-01-01

In this technical document, we describe the development of the Aviation System Analysis Capability (ASAC) Executive Assistant (EA) Proof of Concept (POC) and Beta version. We describe the genesis and role of the ASAC system, discuss the objectives of the ASAC system and provide an overview of components and models in the ASAC system, and describe the design process and the results of the ASAC EA POC and Beta system development. We also describe the evaluation process and results for applicable COTS software. The document has seven chapters, a bibliography, and two appendices.

ASAC Executive Assistant Architecture Description Summary

NASA Technical Reports Server (NTRS)

Roberts, Eileen; Villani, James A.

1997-01-01

In this technical document, we describe the system architecture developed for the Aviation System Analysis Capability (ASAC) Executive Assistant (EA). We describe the genesis and role of the ASAC system, discuss the objectives of the ASAC system and provide an overview of components and models within the ASAC system, discuss our choice for an architecture methodology, the Domain Specific Software Architecture (DSSA), and the DSSA approach to developing a system architecture, and describe the development process and the results of the ASAC EA system architecture. The document has six appendices.

Components of Comprehensive School and School District Emergency Management Plans. Helpful Hints for School Emergency Management. Volume 2, Issue 2, 2007

ERIC Educational Resources Information Center

US Department of Education, 2007

2007-01-01

"Helpful Hints" offers a quick overview of school emergency preparedness topics that are frequently the subject of inquiries. This issue describes and contains a checklist that can assist schools and school districts in developing a new emergency management plan or refreshing their current one. To use the checklist, individuals should consider…

A System for the Individualization and Optimization of Learning Through Computer Management of the Educational Process. Final Report.

ERIC Educational Resources Information Center

Schure, Alexander

A computer-based system model for the monitoring and management of the instructional process was conceived, developed and refined through the techniques of systems analysis. This report describes the various aspects and components of this project in a series of independent and self-contained units. The first unit provides an overview of the entire…

In-Space Propulsion (ISP) Solar Sail Propulsion Technology Development

NASA Technical Reports Server (NTRS)

Montgomery, Edward E., IV

2004-01-01

An overview of the rationale and content for Solar Sail Propulsion (SSP), the on-going project to advance solar technology from technology readiness level 3 to 6 will be provided. A descriptive summary of the major and minor component efforts underway will include identification of the technology providers and a listing of anticipated products Recent important results from major system ground demonstrators will be provided. Finally, a current status of all activities will provided along with the most recent roadmap for the SSP technology development program.

Clock Technology Development in the Laser Cooling and Atomic Physics (LCAP) Program

NASA Technical Reports Server (NTRS)

Seidel, Dave; Thompson, R. J.; Klipstein, W. M.; Kohel, J.; Maleki, L.

2000-01-01

This paper presents the Laser Cooling and Atomic Physics (LCAP) program. It focuses on clock technology development. The topics include: 1) Overview of LCAP Flight Projects; 2) Space Clock 101; 3) Physics with Clocks in microgravity; 4) Space Clock Challenges; 5) LCAP Timeline; 6) International Space Station (ISS) Science Platforms; 7) ISS Express Rack; 8) Space Qualification of Components; 9) Laser Configuration; 10) Clock Rate Comparisons: GPS Carrier Phase Frequency Transfer; and 11) ISS Model Views. This paper is presented in viewgraph form.

Electronic Components and Systems for Cryogenic Space Applications

NASA Technical Reports Server (NTRS)

Patterson, R. L.; Hammoud, A.; Dickman, J. E.; Gerber, S.; Elbuluk, M. E.; Overton, E.

2001-01-01

Electronic components and systems capable of operation at cryogenic temperatures are anticipated in many future NASA space missions such as deep space probes and planetary surface exploration. For example, an unheated interplanetary probe launched to explore the rings of Saturn would reach an average temperature near Saturn of about - 183 C. In addition to surviving the deep space harsh environment, electronics capable of low temperature operation would contribute to improving circuit performance, increasing system efficiency, and reducing payload development and launch costs. Terrestrial applications where components and systems must operate in low temperature environments include cryogenic instrumentation, superconducting magnetic energy storage, magnetic levitation transportation system, and arctic exploration. An on-going research and development program at the NASA Glenn Research Center focuses on the development of reliable electronic devices and efficient power systems capable of surviving in low temperature environments. An overview of the program will be presented in this paper. A description of the low temperature test facilities along with selected data obtained from in-house component testing will also be discussed. Ongoing research activities that are being performed in collaboration with various organizations will also be presented.

Overview of the U.S. Coast Guard short range aids to navigation mission

DOT National Transportation Integrated Search

1993-09-01

This document provides an overview of the Coast Guard's Aids to Navigation (ATON) mission. Specific components of the mission described within include: the history of the mission; the supporting Coast Guard organizational structure; the resources emp...

Strategic Analysis Overview

NASA Technical Reports Server (NTRS)

Cirillo, William M.; Earle, Kevin D.; Goodliff, Kandyce E.; Reeves, J. D.; Stromgren, Chel; Andraschko, Mark R.; Merrill, R. Gabe

2008-01-01

NASA s Constellation Program employs a strategic analysis methodology in providing an integrated analysis capability of Lunar exploration scenarios and to support strategic decision-making regarding those scenarios. The strategic analysis methodology integrates the assessment of the major contributors to strategic objective satisfaction performance, affordability, and risk and captures the linkages and feedbacks between all three components. Strategic analysis supports strategic decision making by senior management through comparable analysis of alternative strategies, provision of a consistent set of high level value metrics, and the enabling of cost-benefit analysis. The tools developed to implement the strategic analysis methodology are not element design and sizing tools. Rather, these models evaluate strategic performance using predefined elements, imported into a library from expert-driven design/sizing tools or expert analysis. Specific components of the strategic analysis tool set include scenario definition, requirements generation, mission manifesting, scenario lifecycle costing, crew time analysis, objective satisfaction benefit, risk analysis, and probabilistic evaluation. Results from all components of strategic analysis are evaluated a set of pre-defined figures of merit (FOMs). These FOMs capture the high-level strategic characteristics of all scenarios and facilitate direct comparison of options. The strategic analysis methodology that is described in this paper has previously been applied to the Space Shuttle and International Space Station Programs and is now being used to support the development of the baseline Constellation Program lunar architecture. This paper will present an overview of the strategic analysis methodology and will present sample results from the application of the strategic analysis methodology to the Constellation Program lunar architecture.

Flow dynamic environment data base development for the SSME

NASA Technical Reports Server (NTRS)

Sundaram, C. V.

1985-01-01

The fluid flow-induced vibration of the Space Shuttle main engine (SSME) components are being studied with a view to correlating the frequency characteristics of the pressure fluctuations in a rocket engine to its operating conditions and geometry. An overview of the data base development for SSME test firing results and the interactive computer software used to access, retrieve, and plot or print the results selectively for given thrust levels, engine numbers, etc., is presented. The various statistical methods available in the computer code for data analysis are discussed. Plots of test data, nondimensionalized using parameters such as fluid flow velocities, densities, and pressures, are presented. Results are compared with those available in the literature. Correlations between the resonant peaks observed at higher frequencies in power spectral density plots with pump geometry and operating conditions are discussed. An overview of the status of the investigation is presented and future directions are discussed.

Improving human activity recognition and its application in early stroke diagnosis.

PubMed

Villar, José R; González, Silvia; Sedano, Javier; Chira, Camelia; Trejo-Gabriel-Galan, Jose M

2015-06-01

The development of efficient stroke-detection methods is of significant importance in today's society due to the effects and impact of stroke on health and economy worldwide. This study focuses on Human Activity Recognition (HAR), which is a key component in developing an early stroke-diagnosis tool. An overview of the proposed global approach able to discriminate normal resting from stroke-related paralysis is detailed. The main contributions include an extension of the Genetic Fuzzy Finite State Machine (GFFSM) method and a new hybrid feature selection (FS) algorithm involving Principal Component Analysis (PCA) and a voting scheme putting the cross-validation results together. Experimental results show that the proposed approach is a well-performing HAR tool that can be successfully embedded in devices.

Pieces of the Puzzle: Tracking the Chemical Component of the ...

EPA Pesticide Factsheets

This presentation provides an overview of the risk assessment conducted at the U.S. EPA, as well as some research examples related to the exposome concept. This presentation also provides the recommendation of using two organizational and predictive frameworks for tracking chemical components in the exposome. The National Exposure Research Laboratory (NERL) Computational Exposure Division (CED) develops and evaluates data, decision-support tools, and models to be applied to media-specific or receptor-specific problem areas. CED uses modeling-based approaches to characterize exposures, evaluate fate and transport, and support environmental diagnostics/forensics with input from multiple data sources. It also develops media- and receptor-specific models, process models, and decision support tools for use both within and outside of EPA.

NASA's Exploration Technology Development Program Energy Storage Project Battery Technology Development

NASA Technical Reports Server (NTRS)

Reid, Concha M.; Miller, Thomas B.; Mercer, Carolyn R.; Jankovsky, Amy L.

2010-01-01

Technical Interchange Meeting was held at Saft America s Research and Development facility in Cockeysville, Maryland on Sept 28th-29th, 2010. The meeting was attended by Saft, contractors who are developing battery component materials under contracts awarded through a NASA Research Announcement (NRA), and NASA. This briefing presents an overview of the components being developed by the contractor attendees for the NASA s High Energy (HE) and Ultra High Energy (UHE) cells. The transition of the advanced lithium-ion cell development project at NASA from the Exploration Technology Development Program Energy Storage Project to the Enabling Technology Development and Demonstration High Efficiency Space Power Systems Project, changes to deliverable hardware and schedule due to a reduced budget, and our roadmap to develop cells and provide periodic off-ramps for cell technology for demonstrations are discussed. This meeting gave the materials and cell developers the opportunity to discuss the intricacies of their materials and determine strategies to address any particulars of the technology.

The Numerical Propulsion System Simulation: An Overview

NASA Technical Reports Server (NTRS)

Lytle, John K.

2000-01-01

Advances in computational technology and in physics-based modeling are making large-scale, detailed simulations of complex systems possible within the design environment. For example, the integration of computing, communications, and aerodynamics has reduced the time required to analyze major propulsion system components from days and weeks to minutes and hours. This breakthrough has enabled the detailed simulation of major propulsion system components to become a routine part of designing systems, providing the designer with critical information about the components early in the design process. This paper describes the development of the numerical propulsion system simulation (NPSS), a modular and extensible framework for the integration of multicomponent and multidisciplinary analysis tools using geographically distributed resources such as computing platforms, data bases, and people. The analysis is currently focused on large-scale modeling of complete aircraft engines. This will provide the product developer with a "virtual wind tunnel" that will reduce the number of hardware builds and tests required during the development of advanced aerospace propulsion systems.

MRMAide: a mixed resolution modeling aide

NASA Astrophysics Data System (ADS)

Treshansky, Allyn; McGraw, Robert M.

2002-07-01

The Mixed Resolution Modeling Aide (MRMAide) technology is an effort to semi-automate the implementation of Mixed Resolution Modeling (MRM). MRMAide suggests ways of resolving differences in fidelity and resolution across diverse modeling paradigms. The goal of MRMAide is to provide a technology that will allow developers to incorporate model components into scenarios other than those for which they were designed. Currently, MRM is implemented by hand. This is a tedious, error-prone, and non-portable process. MRMAide, in contrast, will automatically suggest to a developer where and how to connect different components and/or simulations. MRMAide has three phases of operation: pre-processing, data abstraction, and validation. During pre-processing the components to be linked together are evaluated in order to identify appropriate mapping points. During data abstraction those mapping points are linked via data abstraction algorithms. During validation developers receive feedback regarding their newly created models relative to existing baselined models. The current work presents an overview of the various problems encountered during MRM and the various technologies utilized by MRMAide to overcome those problems.

The ITER bolometer diagnostic: Status and plansa)

NASA Astrophysics Data System (ADS)

Meister, H.; Giannone, L.; Horton, L. D.; Raupp, G.; Zeidner, W.; Grunda, G.; Kalvin, S.; Fischer, U.; Serikov, A.; Stickel, S.; Reichle, R.

2008-10-01

A consortium consisting of four EURATOM Associations has been set up to develop the project plan for the full development of the ITER bolometer diagnostic and to continue urgent R&D activities. An overview of the current status is given, including detector development, line-of-sight optimization, performance analysis as well as the design of the diagnostic components and their integration in ITER. This is complemented by the presentation of plans for future activities required to successfully implement the bolometer diagnostic, ranging from the detector development over diagnostic design and prototype testing to RH tools for calibration.

Integrated Radio and Optical Communication (iROC)

NASA Technical Reports Server (NTRS)

Raible, Daniel; Romanofsky, Robert; Pease, Gary; Kacpura, Thomas

2016-01-01

This is an overview of the Integrated Radio and Optical Communication (iROC) Project for Space Communication and Navigation Industry Days. The Goal is to develop and demonstrate new, high payoff space technologies that will promote mission utilization of optical communications, thereby expanding the capabilities of NASA's exploration, science, and discovery missions. This is an overview that combines the paramount features of select deep space RF and optical communications elements into an integrated system, scalable from deep space to near earth. It will realize Ka-band RF and 1550 nanometer optical capability. The approach is to prototype and demonstrate performance of key components to increase to TRL-5, leading to integrated hybrid communications system demonstration to increase to TRL-5, leading to integrated hybrid communications system demonstration.

Seals/Secondary Fluid Flows Workshop 1997; Volume II: HSR Engine Special Session

NASA Technical Reports Server (NTRS)

Hendricks, Robert C. (Editor)

2006-01-01

The High Speed Civil Transport (HSCT) will be the largest engine ever built and operated at maximum conditions for long periods of time. It is being developed collaboratively with NASA, FAA, Boeing-McDonnell Douglas, Pratt & Whitney, and General Electric. This document provides an initial step toward defining high speed research (HSR) sealing needs. The overview for HSR seals includes defining objectives, summarizing sealing and material requirements, presenting relevant seal cross-sections, and identifying technology needs. Overview presentations are given for the inlet, turbomachinery, combustor and nozzle. The HSCT and HSR seal issues center on durability and efficiency of rotating equipment seals, structural seals and high speed bearing and sump seals. Tighter clearances, propulsion system size and thermal requirements challenge component designers.

Nondestructive Examination Guidance for Dry Storage Casks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyer, Ryan M.; Suffield, Sarah R.; Hirt, Evelyn H.

In this report, an assessment of NDE methods is performed for components of NUHOMS 80 and 102 dry storage system components in an effort to assist NRC staff with review of license renewal applications. The report considers concrete components associated with the horizontal storage modules (HSMs) as well as metal components in the HSMs. In addition, the report considers the dry shielded canister (DSC). Scope is limited to NDE methods that are considered most likely to be proposed by licensees. The document, ACI 349.3R, Evaluation of Existing Nuclear Safety-Related Concrete Structures, is used as the basis for the majority ofmore » the NDE methods summarized for inspecting HSM concrete components. Two other documents, ACI 228.2R, Nondestructive Test Methods for Evaluation of Concrete in Structures, and ORNL/TM-2007/191, Inspection of Nuclear Power Plant Structure--Overview of Methods and Related Application, supplement the list with additional technologies that are considered applicable. For the canister, the ASME B&PV Code is used as the basis for NDE methods considered, along with currently funded efforts through industry (Electric Power Research Institute [EPRI]) and the U.S. Department of Energy (DOE) to develop inspection technologies for canisters. The report provides a description of HSM and DSC components with a focus on those aspects of design considered relevant to inspection. This is followed by a brief description of other concrete structural components such as bridge decks, dams, and reactor containment structures in an effort to facilitate comparison between these structures and HSM concrete components and infer which NDE methods may work best for certain HSM concrete components based on experience with these other structures. Brief overviews of the NDE methods are provided with a focus on issues and influencing factors that may impact implementation or performance. An analysis is performed to determine which NDE methods are most applicable to specific components.« less

FLASH fly-by-light flight control demonstration results overview

NASA Astrophysics Data System (ADS)

Halski, Don J.

1996-10-01

The Fly-By-Light Advanced Systems Hardware (FLASH) program developed Fly-By-Light (FBL) and Power-By-Wire (PBW) technologies for military and commercial aircraft. FLASH consists of three tasks. Task 1 developed the fiber optic cable, connectors, testers and installation and maintenance procedures. Task 3 developed advanced smart, rotary thin wing and electro-hydrostatic (EHA) actuators. Task 2, which is the subject of this paper,l focused on integration of fiber optic sensors and data buses with cable plant components from Task 1 and actuators from Task 3 into centralized and distributed flight control systems. Both open loop and piloted hardware-in-the-loop demonstrations were conducted with centralized and distributed flight control architectures incorporating the AS-1773A optical bus, active hand controllers, optical sensors, optimal flight control laws in high speed 32-bit processors, and neural networks for EHA monitoring and fault diagnosis. This paper overviews the systems level testing conducted under the FLASH Flight Control task. Preliminary results are summarized. Companion papers provide additional information.

New developments in the McStas neutron instrument simulation package

NASA Astrophysics Data System (ADS)

Willendrup, P. K.; Knudsen, E. B.; Klinkby, E.; Nielsen, T.; Farhi, E.; Filges, U.; Lefmann, K.

2014-07-01

The McStas neutron ray-tracing software package is a versatile tool for building accurate simulators of neutron scattering instruments at reactors, short- and long-pulsed spallation sources such as the European Spallation Source. McStas is extensively used for design and optimization of instruments, virtual experiments, data analysis and user training. McStas was founded as a scientific, open-source collaborative code in 1997. This contribution presents the project at its current state and gives an overview of the main new developments in McStas 2.0 (December 2012) and McStas 2.1 (expected fall 2013), including many new components, component parameter uniformisation, partial loss of backward compatibility, updated source brilliance descriptions, developments toward new tools and user interfaces, web interfaces and a new method for estimating beam losses and background from neutron optics.

NEMS - National Energy Modeling System: An Overview

EIA Publications

2009-01-01

The National Energy Modeling System: An Overview 2009 a summary description of NEMS and each of its components. NEMS is a computer-based, energy-economy modeling system of energy markets for the midterm period through 2030. The NEMS is used to produce the Annual Energy Outlook.

An overview of the current technology relevant to the design and development of the Space Transportation Main Engine (STME)

NASA Technical Reports Server (NTRS)

Das, Digendra K.

1991-01-01

The objective of this project was to review the latest literature relevant to the Space Transportation Main Engine (STME). The search was focused on the following engine components: (1) gas generator; (2) hydrostatic/fluid bearings; (3) seals/clearances; (4) heat exchanges; (5) nozzles; (6) nozzle/main combustion chamber joint; (7) main injector face plate; and (8) rocket engine.

Space station power management and distribution

NASA Technical Reports Server (NTRS)

Teren, F.

1985-01-01

The power system architecture is presented by a series of schematics which illustrate the power management and distribution (PMAD) system at the component level, including converters, controllers, switchgear, rotary power transfer devices, power and data cables, remote power controllers, and load converters. Power distribution options, reference power management, and control strategy are also outlined. A summary of advanced development status and plans and an overview of system test plans are presented.

Executive overview and introduction to the SMAP information system life-cycle and documentation standards

NASA Technical Reports Server (NTRS)

1989-01-01

An overview of the five volume set of Information System Life-Cycle and Documentation Standards is provided with information on its use. The overview covers description, objectives, key definitions, structure and application of the standards, and document structure decisions. These standards were created to provide consistent NASA-wide structures for coordinating, controlling, and documenting the engineering of an information system (hardware, software, and operational procedures components) phase by phase.

Overview Snapshot Observational Technique (OSOT): Administration Manual Experimental Research Form.

ERIC Educational Resources Information Center

Coller, Alan R.

Overview Snapshot Observational Technical (OSOT) is specifically designed to allow users to obtain both pictorial and categorical data related to the transactions in context component of early childhood (prekindergarten and kindergarten) educational programs. Such information is especially useful in operations calling for descriptive evaluation.…

A Brief Overview of Open Classroom Education.

ERIC Educational Resources Information Center

Newman, Sally

This brief overview is intended for educators concerned with the realities of implementation and techniques for operational success in open classroom education. Presented are enumerations of statements on 1) essential environmental components that exist in a successful classroom in which the childs' needs, intellectual, and social abilities are…

Characterization of Hippo Pathway Components by Gene Inactivation.

PubMed

Plouffe, Steven W; Meng, Zhipeng; Lin, Kimberly C; Lin, Brian; Hong, Audrey W; Chun, Justin V; Guan, Kun-Liang

2016-12-01

The Hippo pathway is important for regulating tissue homeostasis, and its dysregulation has been implicated in human cancer. However, it is not well understood how the Hippo pathway becomes dysregulated because few mutations in core Hippo pathway components have been identified. Therefore, much work in the Hippo field has focused on identifying upstream regulators, and a complex Hippo interactome has been identified. Nevertheless, it is not always clear which components are the most physiologically relevant in regulating YAP/TAZ. To provide an overview of important Hippo pathway components, we created knockout cell lines for many of these components and compared their relative contributions to YAP/TAZ regulation in response to a wide range of physiological signals. By this approach, we provide an overview of the functional importance of many Hippo pathway components and demonstrate NF2 and RHOA as important regulators of YAP/TAZ and TAOK1/3 as direct kinases for LATS1/2. Copyright © 2016 Elsevier Inc. All rights reserved.

Extensible Hardware Architecture for Mobile Robots

NASA Technical Reports Server (NTRS)

Park, Eric; Kobayashi, Linda; Lee, Susan Y.

2005-01-01

The Intelligent Robotics Group at NASA Ames Research Center has developed a new mobile robot hardware architecture designed for extensibility and reconfigurability. Currently implemented on the k9 rover. and won to be integrated onto the K10 series of human-robot collaboration research robots, this architecture allows for rapid changes in instrumentation configuration and provides a high degree of modularity through a synergistic mix of off-the-shelf and custom designed components, allowing eased transplantation into a wide vane6 of mobile robot platforms. A component level overview of this architecture is presented along with a description of the changes required for implementation on K10 , followed by plans for future work.

Nontraditional inheritance: Genetics and the nature of science, now titled, The puzzle of inheritance: Genetics and the methods of science. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

McInerney, J.D.

1998-08-31

This project led to the development of an instructional module designed for use in high school biology classes. The module contains two major components. The first is an overview for teachers, which introduces the module, describes the Human Genome Project, and addresses issues in the philosophy of science and some of the ethical, legal, and social implications of research in genetics. It provides a survey of fundamental genetics concepts and of new, nontraditional concepts of inheritance. The second component provides six instructional activities appropriate for high school or introductory college students.

Targeting the Hippo signalling pathway for cancer treatment.

PubMed

Nakatani, Keisuke; Maehama, Tomohiko; Nishio, Miki; Goto, Hiroki; Kato, Wakako; Omori, Hirofumi; Miyachi, Yosuke; Togashi, Hideru; Shimono, Yohei; Suzuki, Akira

2017-03-01

The Hippo signalling pathway monitors cell-cell contact and external factors that shape tissue structure. In mice, tumourigenesis and developmental abnormalities are common consequences of dysregulated Hippo signalling. Expression of Hippo pathway components is also frequently altered in human tumours and correlates with poor prognosis and reduced patient survival. Thus, the Hippo pathway is an attractive anti-cancer target. Here, we provide an overview of the function and regulation of Hippo signalling components and summarize progress to date on the development of agents able to regulate Hippo signalling for cancer therapy. © The Authors 2016. Published by Oxford University Press on behalf of the Japanese Biochemical Society. All rights reserved.

The image-guided surgery toolkit IGSTK: an open source C++ software toolkit.

PubMed

Enquobahrie, Andinet; Cheng, Patrick; Gary, Kevin; Ibanez, Luis; Gobbi, David; Lindseth, Frank; Yaniv, Ziv; Aylward, Stephen; Jomier, Julien; Cleary, Kevin

2007-11-01

This paper presents an overview of the image-guided surgery toolkit (IGSTK). IGSTK is an open source C++ software library that provides the basic components needed to develop image-guided surgery applications. It is intended for fast prototyping and development of image-guided surgery applications. The toolkit was developed through a collaboration between academic and industry partners. Because IGSTK was designed for safety-critical applications, the development team has adopted lightweight software processes that emphasizes safety and robustness while, at the same time, supporting geographically separated developers. A software process that is philosophically similar to agile software methods was adopted emphasizing iterative, incremental, and test-driven development principles. The guiding principle in the architecture design of IGSTK is patient safety. The IGSTK team implemented a component-based architecture and used state machine software design methodologies to improve the reliability and safety of the components. Every IGSTK component has a well-defined set of features that are governed by state machines. The state machine ensures that the component is always in a valid state and that all state transitions are valid and meaningful. Realizing that the continued success and viability of an open source toolkit depends on a strong user community, the IGSTK team is following several key strategies to build an active user community. These include maintaining a users and developers' mailing list, providing documentation (application programming interface reference document and book), presenting demonstration applications, and delivering tutorial sessions at relevant scientific conferences.

An Overview of the Parent Project.

ERIC Educational Resources Information Center

Wohlford, Paul

An overview is presented of the final report of the Parent Project, which sought to demonstrate whether participant group methods are suitable for helping low-income parents help themselves and their preschool children in Head Start. The nature, rationale, and interrelationships among the various components of the project are specified. The first…

Entrepreneurship. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on entrepreneurship for students in grades 6-10 consists of a technology education overview, information on use, and instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

Introduction to Animation. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on introduction to animation for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Section components are described next. The…

Audiovisual Programming. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on audiovisual programming for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections…

Health Occupations. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on health occupations for students in grades 6-10 consists of a technology education overview, information on use, and instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

Electronic Publishing. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on electronic publishing for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor and student sections are…

Career Search. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on career search for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

Integrating model behavior, optimization, and sensitivity/uncertainty analysis: overview and application of the MOUSE software toolbox

USDA-ARS?s Scientific Manuscript database

This paper provides an overview of the Model Optimization, Uncertainty, and SEnsitivity Analysis (MOUSE) software application, an open-source, Java-based toolbox of visual and numerical analysis components for the evaluation of environmental models. MOUSE is based on the OPTAS model calibration syst...

Recent progress on nanoparticle-based drug delivery systems for cancer therapy

PubMed Central

Xin, Yanru; Yin, Mingming; Zhao, Liyuan; Meng, Fanling; Luo, Liang

2017-01-01

The development of cancer nanotherapeutics has attracted great interest in the recent decade. Cancer nanotherapeutics have overcome several limitations of conventional therapies, such as nonspecific biodistribution, poor water solubility, and limited bioavailability. Nanoparticles with tuned size and surface characteristics are the key components of nanotherapeutics, and are designed to passively or actively deliver anti-cancer drugs to tumor cells. We provide an overview of nanoparticle-based drug delivery methods and cancer therapies based on tumor-targeting delivery strategies that have been developed in recent years. PMID:28884040

Automotive Stirling engine development program - Overview and status report

NASA Technical Reports Server (NTRS)

Nightingale, N. P.

1983-01-01

The current status of the automotive-Stirling-engine development program being undertaken by DOE and NASA Lewis is reviewed. The program goals and the reference-engine design are explained, and the modifications introduced to improve performance and lower manufacturing costs are discussed and illustrated, including part-power optimization; increased operating temperature (from 720 to 820 C); 45.4-kg weight reduction; elimination of Co and reduction of Cr used; and improved seals, ceramic components, and high-temperature alloys. The test program, some difficulties encountered, and results after 2042 h are summarized.

Overview of Aerothermodynamic Loads Definition Study

NASA Technical Reports Server (NTRS)

Povinelli, L. A.

1985-01-01

The Aerothermodynamic Loads Definition were studied to develop methods to more accurately predict the operating environment in the space shuttle main engine (SSME) components. Development of steady and time-dependent, three-dimensional viscous computer codes and experimental verification and engine diagnostic testing are considered. The steady, nonsteady, and transient operating loads are defined to accurately predict powerhead life. Improvements in the structural durability of the SSME turbine drive systems depends on the knowledge of the aerothermodynamic behavior of the flow through the preburner, turbine, turnaround duct, gas manifold, and injector post regions.

NPSS Overview to TAFW Multidisciplinary Simulation Capabilities

NASA Technical Reports Server (NTRS)

Owen, Karl

2002-01-01

The Numerical Propulsion System Simulation (NPSS) is a concerted effort by NASA Glenn Research Center, the aerospace industry, and academia to develop an advanced engineering environment or integrated collection of software programs for the analysis and design of aircraft engines and, eventually, space transportation components. NPSS is now being applied by GE ground power to ground power generation with the view of expanding the capability to nontraditional power plant applications (example: fuel cells) and NPSS has an interest in in-space power and will be developing those simulation capabilities.

Weight minimization of structural components for launch in space shuttle

NASA Technical Reports Server (NTRS)

Patnaik, Surya N.; Gendy, Atef S.; Hopkins, Dale A.; Berke, Laszlo

1994-01-01

Minimizing the weight of structural components of the space station launched into orbit in a space shuttle can save cost, reduce the number of space shuttle missions, and facilitate on-orbit fabrication. Traditional manual design of such components, although feasible, cannot represent a minimum weight condition. At NASA Lewis Research Center, a design capability called CometBoards (Comparative Evaluation Test Bed of Optimization and Analysis Routines for the Design of Structures) has been developed especially for the design optimization of such flight components. Two components of the space station - a spacer structure and a support system - illustrate the capability of CometBoards. These components are designed for loads and behavior constraints that arise from a variety of flight accelerations and maneuvers. The optimization process using CometBoards reduced the weights of the components by one third from those obtained with traditional manual design. This paper presents a brief overview of the design code CometBoards and a description of the space station components, their design environments, behavior limitations, and attributes of their optimum designs.

IPG Power Grid Overview

NASA Technical Reports Server (NTRS)

Hinke, Thomas

2003-01-01

This presentation will describe what is meant by grids and then cover the current state of the IPG. This will include an overview of the middleware that is key to the operation of the grid. The presentation will then describe some of the future directions that are planned for the IPG. Finally the presentation will conclude with a brief overview of the Global Grid Forum, which is a key activity that will contribute to the successful availability of grid components.

Computational Methods for Biomolecular Electrostatics

PubMed Central

Dong, Feng; Olsen, Brett; Baker, Nathan A.

2008-01-01

An understanding of intermolecular interactions is essential for insight into how cells develop, operate, communicate and control their activities. Such interactions include several components: contributions from linear, angular, and torsional forces in covalent bonds, van der Waals forces, as well as electrostatics. Among the various components of molecular interactions, electrostatics are of special importance because of their long range and their influence on polar or charged molecules, including water, aqueous ions, and amino or nucleic acids, which are some of the primary components of living systems. Electrostatics, therefore, play important roles in determining the structure, motion and function of a wide range of biological molecules. This chapter presents a brief overview of electrostatic interactions in cellular systems with a particular focus on how computational tools can be used to investigate these types of interactions. PMID:17964951

Aircraft energy efficiency. Overview

NASA Technical Reports Server (NTRS)

1981-01-01

Six advanced technology development projects that could cut fuel consumption of future civil air transports by as much as 50 percent are highlighted. These include improved engine components; better engine design; thin short blades for turboprop aircaft; using composite primary structures for weight reduction; the use of supercritical wings, higher aspect ratio, and winglets for improved aerodynamics; active controls; and laminar flow control. The time span of each of the six efforts and NASA's expected expenditures are also discussed.

An Overview of ANN Application in the Power Industry

NASA Technical Reports Server (NTRS)

Niebur, D.

1995-01-01

The paper presents a survey on the development and experience with artificial neural net (ANN) applications for electric power systems, with emphasis on operational systems. The organization and constraints of electric utilities are reviewed, motivations for investigating ANN are identified, and a current assessment is given from the experience of 2400 projects using ANN for load forecasting, alarm processing, fault detection, component fault diagnosis, static and dynamic security analysis, system planning, and operation planning.

Computer aided system engineering and analysis (CASE/A) modeling package for ECLS systems - An overview

NASA Technical Reports Server (NTRS)

Dalee, Robert C.; Bacskay, Allen S.; Knox, James C.

1990-01-01

An overview of the CASE/A-ECLSS series modeling package is presented. CASE/A is an analytical tool that has supplied engineering productivity accomplishments during ECLSS design activities. A components verification program was performed to assure component modeling validity based on test data from the Phase II comparative test program completed at the Marshall Space Flight Center. An integrated plotting feature has been added to the program which allows the operator to analyze on-screen data trends or get hard copy plots from within the CASE/A operating environment. New command features in the areas of schematic, output, and model management, and component data editing have been incorporated to enhance the engineer's productivity during a modeling program.

An Overview of the Iowa Flood Forecasting and Monitoring System

NASA Astrophysics Data System (ADS)

Krajewski, W. F.

2016-12-01

Following the 2008 flood that devastated eastern Iowa the state legislators established the Iowa Flood Center at the University of Iowa with the mission of translational research towards flood mitigation. The Center has adavanced several components towards this goal. In particular, the Center has developed (1) state-wide flood inundation maps based on airborne lidar-based topography data and hydraulic models; (2) a network of nearly 250 real-time ultrasonic river stage sensors; (3) a detailed rainfall-runoff model for real time streamflow forecasting; and (4) cyberinfrastructure to acquire and manage data that includes High Performance Computing and browser-based information system designed for use by general public. The author discusses these components, their operational performance and their potential to assist in development of similar nation-wide systems. Specifically, many developments taking place at the National Water Center can benefit from the Iowa system serving as a reference.

Prototyping the HPDP Chip on STM 65 NM Process

NASA Astrophysics Data System (ADS)

Papadas, C.; Dramitinos, G.; Syed, M.; Helfers, T.; Dedes, G.; Schoellkopf, J.-P.; Dugoujon, L.

2011-08-01

Currently Astrium GmbH is involved in the of the High Performance Data Processor (HPDP) development programme for telecommunication applications under a DLR contract. The HPDP project targets the implementation of the commercially available reconfigurable array processor IP (XPP from the company PACT XPP Technologies) in a radiation hardened technology.In the current complementary development phase funded under the Greek Industry Incentive scheme, it is planned to prototype the HPDP chip in commercial STM 65 nm technology. In addition it is also planned to utilise the preliminary radiation hardened components of this library wherever possible.This abstract gives an overview of the HPDP chip architecture, the basic details of the STM 65 nm process and the design flow foreseen for the prototyping. The paper will discuss the development and integration issues involved in using the STM 65 nm process (also including the available preliminary radiation hardened components) for designs targeted to be used in space applications.

Microrandomized trials: An experimental design for developing just-in-time adaptive interventions.

PubMed

Klasnja, Predrag; Hekler, Eric B; Shiffman, Saul; Boruvka, Audrey; Almirall, Daniel; Tewari, Ambuj; Murphy, Susan A

2015-12-01

This article presents an experimental design, the microrandomized trial, developed to support optimization of just-in-time adaptive interventions (JITAIs). JITAIs are mHealth technologies that aim to deliver the right intervention components at the right times and locations to optimally support individuals' health behaviors. Microrandomized trials offer a way to optimize such interventions by enabling modeling of causal effects and time-varying effect moderation for individual intervention components within a JITAI. The article describes the microrandomized trial design, enumerates research questions that this experimental design can help answer, and provides an overview of the data analyses that can be used to assess the causal effects of studied intervention components and investigate time-varying moderation of those effects. Microrandomized trials enable causal modeling of proximal effects of the randomized intervention components and assessment of time-varying moderation of those effects. Microrandomized trials can help researchers understand whether their interventions are having intended effects, when and for whom they are effective, and what factors moderate the interventions' effects, enabling creation of more effective JITAIs. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

Micro-Randomized Trials: An Experimental Design for Developing Just-in-Time Adaptive Interventions

PubMed Central

Klasnja, Predrag; Hekler, Eric B.; Shiffman, Saul; Boruvka, Audrey; Almirall, Daniel; Tewari, Ambuj; Murphy, Susan A.

2015-01-01

Objective This paper presents an experimental design, the micro-randomized trial, developed to support optimization of just-in-time adaptive interventions (JITAIs). JITAIs are mHealth technologies that aim to deliver the right intervention components at the right times and locations to optimally support individuals’ health behaviors. Micro-randomized trials offer a way to optimize such interventions by enabling modeling of causal effects and time-varying effect moderation for individual intervention components within a JITAI. Methods The paper describes the micro-randomized trial design, enumerates research questions that this experimental design can help answer, and provides an overview of the data analyses that can be used to assess the causal effects of studied intervention components and investigate time-varying moderation of those effects. Results Micro-randomized trials enable causal modeling of proximal effects of the randomized intervention components and assessment of time-varying moderation of those effects. Conclusions Micro-randomized trials can help researchers understand whether their interventions are having intended effects, when and for whom they are effective, and what factors moderate the interventions’ effects, enabling creation of more effective JITAIs. PMID:26651463

Overview of the forest health monitoring program

Treesearch

2000-01-01

This paper presents an overview of the Forest Health Monitoring Program (FHM), a partnership among the USDA Forest Service, State Foresters, universities, and the USDI Bureau of Land Management. The purpose of FHM is to annually assess the condition of the nation's forested ecosystems in a standardized way. There are four components of the program - Detection...

Overview of the Forest Health Monitoring Program

Treesearch

2000-01-01

This paper presents an overview of the Forest Health Monitoring Program (FHM), a partnership among the USDA Forest Service, State Foresters, universities, and the USDI Bureau of Land Management. The purpose of FHM is to annually assess the condition of the Nation's forested ecosystems in a standardized way. There are four components of the program-Detection...

Overview of Youth Sports Programs in the United States.

ERIC Educational Resources Information Center

Seefeldt, Vern; And Others

This overview focuses on two out of the six categories of organized youth sports; namely, agency-sponsored and interscholastic athletics. The discussion of the current status and proposed future direction of organized athletics for youth includes seven components of the problem: the role of youth sports in American culture; the role of athletic…

Aerospace and Flight. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on aerospace and flight for students in grades 6-10 consists of a technology education overview, information on use, and instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

An overview of Virginia's computerized crash records systems.

DOT National Transportation Integrated Search

1995-01-01

This report identifies the various components of Virginia's computerized crash records systems and explains how these components process crash data. Emphasis has been placed on recording information that was previously not documented. Most of the sta...

Overview of the Systems Special Investigation Group investigation

NASA Technical Reports Server (NTRS)

Mason, James B.; Dursch, Harry; Edelman, Joel

1993-01-01

The Long Duration Exposure Facility (LDEF) carried a remarkable variety of electrical, mechanical, thermal, and optical systems, subsystems, and components. Nineteen of the fifty-seven experiments flown on LDEF contained functional systems that were active on-orbit. Almost all of the other experiments possessed at least a few specific components of interest to the Systems Special Investigation Group (Systems SIG), such as adhesives, seals, fasteners, optical components, and thermal blankets. Almost all top level functional testing of the active LDEF and experiment systems has been completed. Failure analysis of both LDEF hardware and individual experiments that failed to perform as designed has also been completed. Testing of system components and experimenter hardware of interest to the Systems SIG is ongoing. All available testing and analysis results were collected and integrated by the Systems SIG. An overview of our findings is provided. An LDEF Optical Experiment Database containing information for all 29 optical related experiments is also discussed.

Software for integrated manufacturing systems, part 2

NASA Technical Reports Server (NTRS)

Volz, R. A.; Naylor, A. W.

1987-01-01

Part 1 presented an overview of the unified approach to manufacturing software. The specific characteristics of the approach that allow it to realize the goals of reduced cost, increased reliability and increased flexibility are considered. Why the blending of a components view, distributed languages, generics and formal models is important, why each individual part of this approach is essential, and why each component will typically have each of these parts are examined. An example of a specification for a real material handling system is presented using the approach and compared with the standard interface specification given by the manufacturer. Use of the component in a distributed manufacturing system is then compared with use of the traditional specification with a more traditional approach to designing the system. An overview is also provided of the underlying mechanisms used for implementing distributed manufacturing systems using the unified software/hardware component approach.

Toxicological Evaluation of Realistic Emission Source Aerosols (TERESA): Introduction and overview

PubMed Central

Godleski, John J.; Rohr, Annette C.; Kang, Choong M.; Diaz, Edgar A.; Ruiz, Pablo A.; Koutrakis, Petros

2013-01-01

Determining the health impacts of sources and components of fine particulate matter (PM2.5) is an important scientific goal. PM2.5 is a complex mixture of inorganic and organic constituents that are likely to differ in their potential to cause adverse health outcomes. The Toxicological Evaluation of Realistic Emissions of Source Aerosols (TERESA) study focused on two PM sources—coal-fired power plants and mobile sources—and sought to investigate the toxicological effects of exposure to emissions from these sources. The set of papers published here document the power plant experiments. TERESA attempted to delineate health effects of primary particles, secondary (aged) particles, and mixtures of these with common atmospheric constituents. TERESA involved withdrawal of emissions from the stacks of three coal-fired power plants in the United States. The emissions were aged and atmospherically transformed in a mobile laboratory simulating downwind power plant plume processing. Toxicological evaluations were carried out in laboratory rats exposed to different emission scenarios with extensive exposure characterization. The approach employed in TERESA was ambitious and innovative. Technical challenges included the development of stack sampling technology that prevented condensation of water vapor from the power plant exhaust during sampling and transfer, while minimizing losses of primary particles; development and optimization of a photochemical chamber to provide an aged aerosol for animal exposures; development and evaluation of a denuder system to remove excess gaseous components; and development of a mobile toxicology laboratory. This paper provides an overview of the conceptual framework, design, and methods employed in the study. PMID:21639692

ICW eHealth Framework.

PubMed

Klein, Karsten; Wolff, Astrid C; Ziebold, Oliver; Liebscher, Thomas

2008-01-01

The ICW eHealth Framework (eHF) is a powerful infrastructure and platform for the development of service-oriented solutions in the health care business. It is the culmination of many years of experience of ICW in the development and use of in-house health care solutions and represents the foundation of ICW product developments based on the Java Enterprise Edition (Java EE). The ICW eHealth Framework has been leveraged to allow development by external partners - enabling adopters a straightforward integration into ICW solutions. The ICW eHealth Framework consists of reusable software components, development tools, architectural guidelines and conventions defining a full software-development and product lifecycle. From the perspective of a partner, the framework provides services and infrastructure capabilities for integrating applications within an eHF-based solution. This article introduces the ICW eHealth Framework's basic architectural concepts and technologies. It provides an overview of its module and component model, describes the development platform that supports the complete software development lifecycle of health care applications and outlines technological aspects, mainly focusing on application development frameworks and open standards.

Overview of diffraction gratings technologies for spaceflight satellites and ground-based telescopes

NASA Astrophysics Data System (ADS)

Cotel, A.; Liard, A.; Desserouer, F.; Pichon, P.

2017-11-01

The diffraction gratings are widely used in Space-flight satellites for spectrograph instruments or in ground-based telescopes in astronomy. The diffraction gratings are one of the key optical components of such systems and have to exhibit very high optical performances. HORIBA Jobin Yvon S.A.S. (part of HORIBA Group) is in the forefront of such gratings development for more than 40 years. During the past decades, HORIBA Jobin Yvon (HJY) has developed a unique expertise in diffraction grating design and manufacturing processes for holographic, ruled or etched gratings. We will present in this paper an overview of diffraction grating technologies especially designed for space and astronomy applications. We will firstly review the heritage of the company in this field with the space qualification of different grating types. Then, we will describe several key grating technologies developed for specific space or astronomy projects: ruled blazed low groove density plane reflection grating, high-groove density holographic toroidal and spherical grating, and finally transmission Fused Silica Etched (FSE) grism-assembled grating. We will not present the Volume Phase Holographic (VPHG) grating type which is used in Astronomy.

Overview of diffraction gratings technologies for space-flight satellites and astronomy

NASA Astrophysics Data System (ADS)

Cotel, Arnaud; Liard, Audrey; Desserouer, Frédéric; Bonnemason, Francis; Pichon, Pierre

2014-09-01

The diffraction gratings are widely used in Space-flight satellites for spectrograph instruments or in ground-based telescopes in astronomy. The diffraction gratings are one of the key optical components of such systems and have to exhibit very high optical performances. HORIBA Jobin Yvon S.A.S. (part of HORIBA Group) is in the forefront of such gratings development for more than 40 years. During the past decades, HORIBA Jobin Yvon (HJY) has developed a unique expertise in diffraction grating design and manufacturing processes for holographic, ruled or etched gratings. We will present in this paper an overview of diffraction grating technologies especially designed for space and astronomy applications. We will firstly review the heritage of the company in this field with the space qualification of different grating types. Then, we will describe several key grating technologies developed for specific space or astronomy projects: ruled blazed low groove density plane reflection grating, holographic blazed replica plane grating, high-groove density holographic toroidal and spherical grating and transmission Fused Silica Etched (FSE) grismassembled grating.

Hard copies for digital medical images: an overview

NASA Astrophysics Data System (ADS)

Blume, Hartwig R.; Muka, Edward

1995-04-01

This paper is a condensed version of an invited overview on the technology of film hard-copies used in radiology. Because the overview was given to an essentially nonmedical audience, the reliance on film hard-copies in radiology is outlined in greater detail. The overview is concerned with laser image recorders generating monochrome prints on silver-halide films. The basic components of laser image recorders are sketched. The paper concentrates on the physical parameters - characteristic function, dynamic range, digitization resolution, modulation transfer function, and noise power spectrum - which define image quality and information transfer capability of the printed image. A preliminary approach is presented to compare the printed image quality with noise in the acquired image as well as with the noise of state-of- the-art cathode-ray-tube display systems. High-performance laser-image- recorder/silver-halide-film/light-box systems are well capable of reproducing acquired radiologic information. Most recently development was begun toward a display function standard for soft-copy display systems to facilitate similarity of image presentation between different soft-copy displays as well as between soft- and hard-copy displays. The standard display function is based on perceptional linearization. The standard is briefly reviewed to encourage the printer industry to adopt it, too.

Critical Components of Successful Inclusion of Students with Severe Disabilities: Literature Review

ERIC Educational Resources Information Center

Alquraini, Turki; Gut, Dianne

2012-01-01

This paper examines the critical components of successful inclusion for students with severe disabilities. This review sets out to provide an overview of literature regarding effective practices for inclusion with a focus on critical components of successful inclusion that assist in preparing the stakeholders worldwide to work and engage…

Atmospheric Constituents in GEOS-5: Components for an Earth System Model

NASA Technical Reports Server (NTRS)

Pawson, Steven; Douglass, Anne; Duncan, Bryan; Nielsen, Eric; Ott, Leslie; Strode, Sarah

2011-01-01

The GEOS-S model is being developed for weather and climate processes, including the implementation of "Earth System" components. While the stratospheric chemistry capabilities are mature, we are presently extending this to include predictions of the tropospheric composition and chemistry - this includes CO2, CH4, CO, nitrogen species, etc. (Aerosols are also implemented, but are beyond the scope of this paper.) This work will give an overview of our chemistry modules, the approaches taken to represent surface emissions and uptake of chemical species, and some studies of the sensitivity of the atmospheric circulation to changes in atmospheric composition. Results are obtained through focused experiments and multi-decadal simulations.

Overview of thermal barrier coatings in diesel engines

NASA Technical Reports Server (NTRS)

Yonushonis, T. M.

1995-01-01

An understanding of delamination mechanisms in thermal barrier coatings has been developed for diesel applications through nondestructive evaluation, structural analysis modeling and engine evaluation of various thermal barrier coatings. This knowledge has resulted in improved thermal barrier coatings which survive abusive cyclic fatigue tests in high output diesel engines. Significant efforts are still required to improve the plasma spray processing capability and the economics for complex geometry diesel engine components. Data obtained from advanced diesel engines on the effect of thermal barrier coatings on engine fuel economy and emission has not been encouraging. Although the underlying metal component temperatures have been reduced through the use of thermal barrier coating, engine efficiency and emission trends have not been promising.

Projection display technology for avionics applications

NASA Astrophysics Data System (ADS)

Kalmanash, Michael H.; Tompkins, Richard D.

2000-08-01

Avionics displays often require custom image sources tailored to demanding program needs. Flat panel devices are attractive for cockpit installations, however recent history has shown that it is not possible to sustain a business manufacturing custom flat panels in small volume specialty runs. As the number of suppliers willing to undertake this effort shrinks, avionics programs unable to utilize commercial-off-the-shelf (COTS) flat panels are placed in serious jeopardy. Rear projection technology offers a new paradigm, enabling compact systems to be tailored to specific platform needs while using a complement of COTS components. Projection displays enable improved performance, lower cost and shorter development cycles based on inter-program commonality and the wide use of commercial components. This paper reviews the promise and challenges of projection technology and provides an overview of Kaiser Electronics' efforts in developing advanced avionics displays using this approach.

An unstructured-grid software system for solving complex aerodynamic problems

NASA Technical Reports Server (NTRS)

Frink, Neal T.; Pirzadeh, Shahyar; Parikh, Paresh

1995-01-01

A coordinated effort has been underway over the past four years to elevate unstructured-grid methodology to a mature level. The goal of this endeavor is to provide a validated capability to non-expert users for performing rapid aerodynamic analysis and design of complex configurations. The Euler component of the system is well developed, and is impacting a broad spectrum of engineering needs with capabilities such as rapid grid generation and inviscid flow analysis, inverse design, interactive boundary layers, and propulsion effects. Progress is also being made in the more tenuous Navier-Stokes component of the system. A robust grid generator is under development for constructing quality thin-layer tetrahedral grids, along with a companion Navier-Stokes flow solver. This paper presents an overview of this effort, along with a perspective on the present and future status of the methodology.

Overview of NASA Studies on High-Temperature Ceramic Fibers

NASA Technical Reports Server (NTRS)

DiCarlo, James A.; Yun, Hee Mann

2001-01-01

NASA, DOD, and DOE are currently looking to the NASA UEET Program to develop ceramic matrix composites (CMC) for hot-section components in advanced power and propulsion systems - Success will depend strongly on developing ceramic fibers with a variety of key thermostructural properties, in particular, high as-produced tensile strength and retention of a large fraction of this strength for long times under the anticipated CMC service conditions. - Current UEET approach centers on selecting the optimum fiber type from commercially available fibers since the costs for development of advanced fibers are high and the markets for high-temperature CMC have yet to be established.

QUEST/Ada: Query utility environment for software testing of Ada

NASA Technical Reports Server (NTRS)

Brown, David B.

1989-01-01

Results of research and development efforts are presented for Task 1, Phase 2 of a general project entitled, The Development of a Program Analysis Environment for Ada. A prototype of the QUEST/Ada system was developed to collect data to determine the effectiveness of the rule-based testing paradigm. The prototype consists of five parts: the test data generator, the parser/scanner, the test coverage analyzer, a symbolic evaluator, and a data management facility, known as the Librarian. These components are discussed at length. Also presented is an experimental design for the evaluations, an overview of the project, and a schedule for its completion.

An overview on the use of backscattered sound for measuring suspended particle size and concentration profiles in non-cohesive inorganic sediment transport studies

NASA Astrophysics Data System (ADS)

Thorne, Peter D.; Hurther, David

2014-02-01

For over two decades, coastal marine scientists studying boundary layer sediment transport processes have been using, and developing, the application of sound for high temporal-spatial resolution measurements of suspended particle size and concentration profiles. To extract the suspended sediment parameters from the acoustic data requires an understanding of the interaction of sound with a suspension of sediments and an inversion methodology. This understanding is distributed around journals in a number of scientific fields and there is no single article that succinctly draws together the different components. In the present work the aim is to provide an overview on the acoustic approach to measuring suspended sediment parameters and assess its application in the study of non-cohesive inorganic suspended sediment transport processes.

Testing Planetary Rovers: Technologies, Perspectives, and Lessons Learned

NASA Technical Reports Server (NTRS)

Thomas, Hans; Lau, Sonie (Technical Monitor)

1998-01-01

Rovers are a vital component of NASA's strategy for manned and unmanned exploration of space. For the past five years, the Intelligent Mechanisms Group at the NASA Ames Research Center has conducted a vigorous program of field testing of rovers from both technology and science team productivity perspective. In this talk, I will give an overview of the the last two years of the test program, focusing on tests conducted in the Painted Desert of Arizona, the Atacama desert in Chile, and on IMG participation in the Mars Pathfinder mission. An overview of autonomy, manipulation, and user interface technologies developed in response to these missions will be presented, and lesson's learned in these missions and their impact on future flight missions will be presented. I will close with some perspectives on how the testing program has affected current rover systems.

Family Support Programs and Incarcerated Parents: Overview of Family Support Programs.

ERIC Educational Resources Information Center

Family Resource Coalition, Chicago, IL.

This fact sheet begins with an overview of family support programs, which includes a discussion of the premises of family support programs and a list of typical program components. The remainder of the fact sheet focuses on support programs for incarcerated parents. The children of incarcerated parents, though innocent of any crime, are often…

Apollo Command and Service Module Propulsion Systems Overview

NASA Technical Reports Server (NTRS)

Interbartolo, Michael A.

2009-01-01

An overview of the Apollo Command and Service Module (CSM) propulsion systems is provided. The systems for CSM propulsion and control are defined, the times during the mission when each system is used are listed, and, the basic components and operation of the service propulsion system, SM reaction control system and CM reaction control system are described.

Application of Learner Corpora to Second Language Learning and Teaching: An Overview

ERIC Educational Resources Information Center

Xu, Qi

2016-01-01

The paper gives an overview of learner corpora and their application to second language learning and teaching. It is proposed that there are four core components in learner corpus research, namely, corpus linguistics expertise, a good background in linguistic theory, knowledge of SLA theory, and a good understanding of foreign language teaching…

RCRA, superfund and EPCRA hotline training module. Introduction to: RCRA statutory overview updated July 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-07-01

The module presents a brief overview of the Resource Conservation and Recovery Act (RCRA). It explains the relationship between RCRA statutory language and codified regulatory language. It describes the major components of each subtitle of RCRA and identifies the major provisions established by the Hazardous and Solid Waste Amendments (HSWA).

NASA's First Year Progress with Fuel Cell Advanced Development in Support of the Exploration Vision

NASA Technical Reports Server (NTRS)

Hoberecht, Mark

2007-01-01

NASA Glenn Research Center (GRC), in collaboration with Johnson Space Center (JSC), the Jet Propulsion Laboratory (JPL), Kennedy Space Center (KSC), and industry partners, is leading a proton-exchange-membrane fuel cell (PEMFC) advanced development effort to support the vision for Exploration. This effort encompasses the fuel cell portion of the Energy Storage Project under the Exploration Technology Development Program, and is directed at multiple power levels for both primary and regenerative fuel cell systems. The major emphasis is the replacement of active mechanical ancillary components with passive components in order to reduce mass and parasitic power requirements, and to improve system reliability. A dual approach directed at both flow-through and non flow-through PEMFC system technologies is underway. A brief overview of the overall PEMFC project and its constituent tasks will be presented, along with in-depth technical accomplishments for the past year. Future potential technology development paths will also be discussed.

Modeling High-Resolution Coastal Ocean Dynamics with COAMPS: System Overview, Applications and Future Directions

NASA Astrophysics Data System (ADS)

Allard, R. A.; Campbell, T. J.; Edwards, K. L.; Smith, T.; Martin, P.; Hebert, D. A.; Rogers, W.; Dykes, J. D.; Jacobs, G. A.; Spence, P. L.; Bartels, B.

2014-12-01

The Coupled Ocean Atmosphere Mesoscale Prediction System (COAMPS®) is an atmosphere-ocean-wave modeling system developed by the Naval Research Laboratory which can be configured to cycle regional forecasts/analysis models in single-model (atmosphere, ocean, and wave) or coupled-model (atmosphere-ocean, ocean-wave, and atmosphere-ocean-wave) modes. The model coupling is performed using the Earth System Modeling Framework (ESMF). The ocean component is the Navy Coastal Ocean Model (NCOM), and the wave components include Simulating WAves Nearshore (SWAN) and WaveWatch-III. NCOM has been modified to include wetting and drying, the effects of Stokes drift current, wave radiation stresses due to horizontal gradients of the momentum flux of surface waves, enhancement of bottom drag in shallow water, and enhanced vertical mixing due to Langmuir turbulence. An overview of the modeling system including ocean data assimilation and specification of boundary conditions will be presented. Results from a high-resolution (10-250m) modeling study from the Surfzone Coastal Oil Pathways Experiment (SCOPE) near Ft. Walton Beach, Florida in December 2013 will be presented. ®COAMPS is a registered trademark of the Naval Research Laboratory

Designing components using smartMOVE electroactive polymer technology

NASA Astrophysics Data System (ADS)

Rosenthal, Marcus; Weaber, Chris; Polyakov, Ilya; Zarrabi, Al; Gise, Peter

2008-03-01

Designing components using SmartMOVE TM electroactive polymer technology requires an understanding of the basic operation principles and the necessary design tools for integration into actuator, sensor and energy generation applications. Artificial Muscle, Inc. is collaborating with OEMs to develop customized solutions for their applications using smartMOVE. SmartMOVE is an advanced and elegant way to obtain almost any kind of movement using dielectric elastomer electroactive polymers. Integration of this technology offers the unique capability to create highly precise and customized motion for devices and systems that require actuation. Applications of SmartMOVE include linear actuators for medical, consumer and industrial applications, such as pumps, valves, optical or haptic devices. This paper will present design guidelines for selecting a smartMOVE actuator design to match the stroke, force, power, size, speed, environmental and reliability requirements for a range of applications. Power supply and controller design and selection will also be introduced. An overview of some of the most versatile configuration options will be presented with performance comparisons. A case example will include the selection, optimization, and performance overview of a smartMOVE actuator for the cell phone camera auto-focus and proportional valve applications.

Neurotoxic effects of gasoline and gasoline constituents.

PubMed Central

Burbacher, T M

1993-01-01

This overview was developed as part of a symposium on noncancer end points of gasoline and key gasoline components. The specific components included are methyl tertiary butyl ether, ethyl tertiary butyl ether, tertiary amyl methyl ether, butadiene, benzene, xylene, toluene, methyl alcohol, and ethyl alcohol. The overview focuses on neurotoxic effects related to chronic low-level exposures. A few general conclusions and recommendations can be made based on the results of the studies to date. a) All the compounds reviewed are neuroactive and, as such, should be examined for their neurotoxicity. b) For most of the compounds, there is a substantial margin of safety between the current permissible exposure levels and levels that would be expected to cause overt signs of neurotoxicity in humans. This is not the case for xylene, toluene, and methanol, however, where neurologic effects are observed at or below the current Threshold Limit Value. c) For most of the compounds, the relationship between chronic low-level exposure and subtle neurotoxic effects has not been studied. Studies therefore should focus on examining the dose-response relationship between chronic low-level exposure and subtle changes in central nervous system function. PMID:8020437

Sizing Power Components of an Electrically Driven Tail Cone Thruster and a Range Extender

NASA Technical Reports Server (NTRS)

Jansen, Ralph H.; Bowman, Cheryl; Jankovsky, Amy

2016-01-01

The aeronautics industry has been challenged on many fronts to increase efficiency, reduce emissions, and decrease dependency on carbon-based fuels. The NASA Aeronautics Research Mission Directorate has identified a suite of investments to meet long term research demands beyond the purview of commercial investment. Electrification of aviation propulsion through turboelectric or hybrid electric propulsion is one of many exciting research areas which has the potential to revolutionize the aviation industry. This paper will provide an overview of the turboelectric and hybrid electric technologies being developed under NASAs Advanced Air Transportation Technology (AATT) Project, and how these technologies can impact vehicle design. An overview will be presented of vehicle system studies and the electric drive system assumptions for successful turboelectric and hybrid electric propulsion in single aisle size commercial aircraft. Key performance parameters for electric drive system technologies will be reviewed, and the technical investment made in materials, electric machines, power electronics, and integrated power systems will be discussed. Finally, power components for a single aisle turboelectric aircraft with an electrically driven tail cone thruster and a hybrid electric nine passenger aircraft with a range extender will be parametrically sized.

Profiles of Automotive Suppliers Industries--Engineered Mechanical Components and Systems : Volume I, Text.

DOT National Transportation Integrated Search

1981-09-01

This profile describes and analyzes that segment of the automotive supplier industry which provides engineered mechanical components/assemblies/systems to the prime auto manufacturers. It presents an overview of the role and structure of this industr...

Profiles of Automotive Suppliers Industries--Engineered Mechanical Components and Systems : Volume II, Appendices.

DOT National Transportation Integrated Search

1981-09-01

The profile describes and analyzes that segment of the automotive supplier industry which provides engineered mechanical components/assemblies/systems to the prime auto manufacturers. It presents an overview of the role and structure of this industry...

Overview of Rotating Cavitation and Cavitation Surge in the Fastrac Engine LOX Turbopump

NASA Technical Reports Server (NTRS)

Zoladz, Thomas; Turner, Jim (Technical Monitor)

2001-01-01

Observations regarding rotating cavitation and cavitation surge experienced during the development of the Fastrac 60 Klbf engine turbopump are discussed. Detailed observations from the analysis of both water flow and liquid oxygen test data are offered. Scaling and general comparison of rotating cavitation between water flow and liquid oxygen testing are discussed. Complex data features linking the localized rotating cavitation mechanism of the inducer to system surge components are described in detail. Finally a description of a simple lumped-parameter hydraulic system model developed to better understand observed data is given.

Fundamentals and techniques of nonimaging optics, volume 2

NASA Astrophysics Data System (ADS)

Winston, R.; Ogallagher, J. J.

1983-06-01

The formalism describing the operation is being defined, nonimaging concentrators and are being designed, and experiments and analytical studies are being conducted to evaluate the performance of new designs. In addition, components and materials particularly suited for use with these techniques were studied, and applications with an emphasis on solar energy concentration were explored. The motivation for the basic principles of nonimaging optics as they developed before 1978 are surveyed. The present status of the subdiscipline of nonimaging optics is summarized and an overview of the potential for future developments which is just beginning to emerge is presented.

Innovative Materials for Aircraft Morphing

NASA Technical Reports Server (NTRS)

Simpson, J. O.; Wise, S. A.; Bryant, R. G.; Cano, R. J.; Gates, T. S.; Hinkley, J. A.; Rogowski, R. S.; Whitley, K. S.

1997-01-01

Reported herein is an overview of the research being conducted within the Materials Division at NASA Langley Research Center on the development of smart material technologies for advanced airframe systems. The research is a part of the Aircraft Morphing Program which is a new six-year research program to develop smart components for self-adaptive airframe systems. The fundamental areas of materials research within the program are computational materials; advanced piezoelectric materials; advanced fiber optic sensing techniques; and fabrication of integrated composite structures. This paper presents a portion of the ongoing research in each of these areas of materials research.

Transcendent Pluralism: A Middle-Range Theory of Nonviolent Social Transformation Through Human and Ecological Dignity.

PubMed

Perry, Donna J

2015-01-01

Transcendent pluralism is a middle-range theory that focuses on the emergence of human dignity within relationships among diverse peoples through nonviolent social transformation. The theory proposes that contemporary social problems that negatively influence health are rooted in human and ecological devaluation and that healing is needed through the advance of dignity. The theory has been developed through both deductive and inductive processes including 4 research studies. The theory of transcendent pluralism provides a framework for nurses seeking to advance dignity. This article provides an overview of the theory's development and components.

Experimental psychiatric illness and drug abuse models: from human to animal, an overview.

PubMed

Edwards, Scott; Koob, George F

2012-01-01

Preclinical animal models have supported much of the recent rapid expansion of neuroscience research and have facilitated critical discoveries that undoubtedly benefit patients suffering from psychiatric disorders. This overview serves as an introduction for the following chapters describing both in vivo and in vitro preclinical models of psychiatric disease components and briefly describes models related to drug dependence and affective disorders. Although there are no perfect animal models of any psychiatric disorder, models do exist for many elements of each disease state or stage. In many cases, the development of certain models is essentially restricted to the human clinical laboratory domain for the purpose of maximizing validity, whereas the use of in vitro models may best represent an adjunctive, well-controlled means to model specific signaling mechanisms associated with psychiatric disease states. The data generated by preclinical models are only as valid as the model itself, and the development and refinement of animal models for human psychiatric disorders continues to be an important challenge. Collaborative relationships between basic neuroscience and clinical modeling could greatly benefit the development of new and better models, in addition to facilitating medications development.

Recent Developments in Instrumentation for Capillary Electrophoresis and Microchip-Capillary Electrophoresis

PubMed Central

Felhofer, Jessica L.; Blanes, Lucas; Garcia, Carlos D.

2010-01-01

Over the last years there has been an explosion in the number of developments and applications of capillary electrophoresis (CE) and microchip-CE. In part, this growth has been the direct consequence of recent developments in instrumentation associated with CE. This review, which is focused on contributions published in the last five years, is intended to complement the papers presented in this special issue dedicated to Instrumentation and to provide an overview on the general trend and some of the most remarkable developments published in the areas of high voltage power supplies, detectors, auxiliary components, and compact systems. It also includes few examples of alternative uses of and modifications to traditional CE instruments. PMID:20665910

An overview of neural function and feedback control in human communication.

PubMed

Hood, L J

1998-01-01

The speech and hearing mechanisms depend on accurate sensory information and intact feedback mechanisms to facilitate communication. This article provides a brief overview of some components of the nervous system important for human communication and some electrophysiological methods used to measure cortical function in humans. An overview of automatic control and feedback mechanisms in general and as they pertain to the speech motor system and control of the hearing periphery is also presented, along with a discussion of how the speech and auditory systems interact.

Blood banking and transfusion medicine for the nephrologist.

PubMed

Wehrli, Gay

2012-01-01

Therapeutic Apheresis Medicine Services work closely with Blood Banking and Transfusion Medicine Services (BBTMS). The BBTMS performs patient testing and provides blood components for patients undergoing therapeutic apheresis procedures. This article will provide an overview of blood component descriptions, patient testing, and blood component options and preparations for therapeutic apheresis procedures. © 2012 Wiley Periodicals, Inc.

Solar thermal program summary. Volume 1: Overview, fiscal year 1988

NASA Astrophysics Data System (ADS)

1989-02-01

The goal of the solar thermal program is to improve overall solar thermal systems performance and provide cost-effective energy options that are strategically secure and environmentally benign. Major research activities include energy collection technology, energy conversion technology, and systems and applications technology for both CR and DR systems. This research is being conducted through research laboratories in close coordination with the solar thermal industry, utilities companies, and universities. The Solar Thermal Technology Program is pursuing the development of critical components and subsystems for improved energy collection and conversion devices. This development follows two basic paths: for CR systems, critical components include stretched membrane heliostats, direct absorption receivers (DARs), and transport subsystems for molten salt heat transfer fluids. These components offer the potential for a significant reduction in system costs; and for DR systems, critical components include stretched membrane dishes, reflux receivers, and Stirling engines. These components will significantly increase system reliability and efficiency, which will reduce costs. The major thrust of the program is to provide electric power. However, there is an increasing interest in the use of concentrated solar energy for applications such as detoxifying hazardous wastes and developing high-value transportable fuels. These potential uses of highly concentrated solar energy still require additional experiments to prove concept feasibility. The program goal of economically competitive energy reduction from solar thermal systems is being cooperatively addressed by industry and government.

Mississippi River Cultural Resources Survey. A Comprehensive Study. Phase I. Component A. Thematic Historical Overview.

DTIC Science & Technology

1984-05-01

Although it was a very sweet variety, the growers failed to develop a granulation process and at best only obtained syrup from the cane. In addition...and cotton; thus a shift was made in agricultural production. Etienne de Bore, convinced that he could granulate sugar, imported a Tahitian variety of...successfully granulated sugar from the cane the following year and received $12,000 for his crop, a number of other plantation owners emulated him. By

Introduction to wind energy systems

NASA Astrophysics Data System (ADS)

Wagner, H.-J.

2017-07-01

This article presents the basic concepts of wind energy and deals with the physics and mechanics of operation. It describes the conversion of wind energy into rotation of turbine, and the critical parameters governing the efficiency of this conversion. After that it presents an overview of various parts and components of windmills. The connection to the electrical grid, the world status of wind energy use for electricity production, the cost situation and research and development needs are further aspects which will be considered.

Introduction to wind energy systems

NASA Astrophysics Data System (ADS)

Wagner, H.-J.

2015-08-01

This article presents the basic concepts of wind energy and deals with the physics and mechanics of operation. It describes the conversion of wind energy into rotation of turbine, and the critical parameters governing the efficiency of this conversion. After that it presents an overview of various parts and components of windmills. The connection to the electrical grid, the world status of wind energy use for electricity production, the cost situation and research and development needs are further aspects which will be considered.

Savannah River Ecology Laboratory, annual technical progress report of ecological research for the year ending June 30, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wein, G.; Rosier, B.

1998-12-31

This report provides an overview of the research programs and program components carried out by the Savannah River Ecology Laboratory. Research focused on the following: advanced analytical and spectroscopic techniques for developing novel waste isolation and stabilization technologies as well as cost-effective remediation strategies; ecologically sound management of damaged and remediation of ecological systems; ecotoxicology, remediation, and risk assessment; radioecology, including dose assessments for plants and animals exposed to environmental radiation; and other research support programs.

Optical components of adaptive systems for improving laser beam quality

NASA Astrophysics Data System (ADS)

Malakhov, Yuri I.; Atuchin, Victor V.; Kudryashov, Aleksis V.; Starikov, Fedor A.

2008-10-01

The short overview is given of optical equipment developed within the ISTC activity for adaptive systems of new generation allowing for correction of high-power laser beams carrying optical vortices onto the phase surface. They are the kinoform many-level optical elements of new generation, namely, special spiral phase plates and ordered rasters of microlenses, i.e. lenslet arrays, as well as the wide-aperture Hartmann-Shack sensors and bimorph deformable piezoceramics- based mirrors with various grids of control elements.

Overview of innovative PMI research on NSTX-U and associated PMI facilities at PPPL

DOE PAGES

M. Ono; Jaworski, M.; Kaita, R.; ...

2013-05-01

Developing a reactor compatible divertor and managing the associated plasma material interaction (PMI) has been identified as a high priority research area for magnetic confinement fusion. Accordingly on NSTX-U, the PMI research has received a strong emphasis. Moreover, with ˜15 MW of auxiliary heating power, NSTX-U will be able to test the PMI physics with the peak divertor plasma facing component (PFC) heat loads of up to 40-60 MW/m 2.

Control of experimental uncertainties in filtered Rayleigh scattering measurements

NASA Technical Reports Server (NTRS)

Forkey, Joseph N.; Finkelstein, N. D.; Lempert, Walter R.; Miles, Richard B.

1995-01-01

Filtered Rayleigh Scattering is a technique which allows for measurement of velocity, temperature, and pressure in unseeded flows, spatially resolved in 2-dimensions. We present an overview of the major components of a Filtered Rayleigh Scattering system. In particular, we develop and discuss a detailed theoretical model along with associated model parameters and related uncertainties. Based on this model, we then present experimental results for ambient room air and for a Mach 2 free jet, including spatially resolved measurements of velocity, temperature, and pressure.

Recent Results from NASA's Morphing Project

NASA Technical Reports Server (NTRS)

McGowan, Anna-Maria R.; Washburn, Anthony E.; Horta, Lucas G.; Bryant, Robert G.; Cox, David E.; Siochi, Emilie J.; Padula, Sharon L.; Holloway, Nancy M.

2002-01-01

The NASA Morphing Project seeks to develop and assess advanced technologies and integrated component concepts to enable efficient, multi-point adaptability in air and space vehicles. In the context of the project, the word "morphing" is defined as "efficient, multi-point adaptability" and may include macro, micro, structural and/or fluidic approaches. The project includes research on smart materials, adaptive structures, micro flow control, biomimetic concepts, optimization and controls. This paper presents an updated overview of the content of the Morphing Project including highlights of recent research results.

Savannah River Ecology Laboratory, annual technical progress report of ecological research for the year ending June 30, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wein, G.; Rosier, B.

1997-12-31

This report provides an overview of the research programs and program components carried out by the Savannah River Ecology Laboratory. Research focused on the following: advanced analytical and spectroscopic techniques for developing novel waste isolation and stabilization technologies as well as cost-effective remediation strategies; ecologically sound management of damaged and remediation of ecological systems; ecotoxicology, remediation, and risk assessment; radioecology, including dose assessments for plants and animals exposed to environmental radiation; and other research support programs.

International Space Station (ISS) Nodes 2/3 Thermal Control System Overview and Design

NASA Technical Reports Server (NTRS)

Clanton, Stephen; Croomes, Scott (Technical Monitor)

2002-01-01

The goals of this viewgraph presentation are to: (1) provide general International Space Station (ISS) Node 2 and 3 information; (2) give an overview of the ISS Thermal Control System (TCS) design, including details on the passive TCS and internal and external TCS; (3) give TCS components examples; and (4) describe the thermal and hydraulic analytical tools.

FIELD TEST OF CYCLODEXTRIN FOR ENHANCED IN-SITU FLUSHING OF MULTIPLE-COMPONENT IMMISCIBLE ORGANIC LIQUID CONTAMINATION: PROJECT OVERVIEW AND INITIAL RESULTS

EPA Science Inventory

The purpose of this paper is to present an overview and the initial results of a pilot-scale experiment designated to test the use of cyclodextrin for enhanced in-situ flushing of an aquifer contaminated by immiscible liquid. This is the first field test of this technology, terme...

RCRA/UST, superfund, and EPCRA hotline training module. Introduction to: RCRA statutory overview, updated as of July 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-11-01

The module presents a brief overview of the Resource Conservation and Recovery Act (RCRA). It explains the relationship between RCRA statutory language and codified regulatory language. It describes the major components of each subtitle of RCRA and identifies the major provisions established by the Hazardous and Solid Waste Amendments (HSWA).

Overview of space power electronic's technology under the CSTI High Capacity Power Program

NASA Technical Reports Server (NTRS)

Schwarze, Gene E.

1994-01-01

The Civilian Space Technology Initiative (CSTI) is a NASA Program targeted at the development of specific technologies in the areas of transportation, operations and science. Each of these three areas consists of major elements and one of the operation's elements is the High Capacity Power element. The goal of this element is to develop the technology base needed to meet the long duration, high capacity power requirements for future NASA initiatives. The High Capacity Power element is broken down into several subelements that includes energy conversion in the areas of the free piston Stirling power converter and thermoelectrics, thermal management, power management, system diagnostics, and environmental compatibility and system's lifetime. A recent overview of the CSTI High capacity Power element and a description of each of the program's subelements is given by Winter (1989). The goals of the Power Management subelement are twofold. The first is to develop, test, and demonstrate high temperature, radiation-resistant power and control components and circuits that will be needed in the Power Conditioning, Control and Transmission (PCCT) subsystem of a space nuclear power system. The results obtained under this goal will also be applicable to the instrumentation and control subsystem of a space nuclear reactor. These components and circuits must perform reliably for lifetimes of 7-10 years. The second goal is to develop analytical models for use in computer simulations of candidate PCCT subsystems. Circuits which will be required for a specific PCCT subsystem will be designed and built to demonstrate their performance and, also, to validate the analytical models and simulations. The tasks under the Power Management subelement will now be described in terms of objectives, approach and present status of work.

Innate immunity of fish (overview).

PubMed

Magnadóttir, Bergljót

2006-02-01

The innate immune system is the only defence weapon of invertebrates and a fundamental defence mechanism of fish. The innate system also plays an instructive role in the acquired immune response and homeostasis and is therefore equally important in higher vertebrates. The innate system's recognition of non-self and danger signals is served by a limited number of germ-line encoded pattern recognition receptors/proteins, which recognise pathogen associated molecular patterns like bacterial and fungal glycoproteins and lipopolysaccharides and intracellular components released through injury or infection. The innate immune system is divided into physical barriers, cellular and humoral components. Humoral parameters include growth inhibitors, various lytic enzymes and components of the complement pathways, agglutinins and precipitins (opsonins, primarily lectins), natural antibodies, cytokines, chemokines and antibacterial peptides. Several external and internal factors can influence the activity of innate immune parameters. Temperature changes, handling and crowding stress can have suppressive effects on innate parameters, whereas several food additives and immunostimulants can enhance different innate factors. There is limited data available about the ontogenic development of the innate immunological system in fish. Active phagocytes, complement components and enzyme activity, like lysozyme and cathepsins, are present early in the development, before or soon after hatching.

A Co-modeling Method Based on Component Features for Mechatronic Devices in Aero-engines

NASA Astrophysics Data System (ADS)

Wang, Bin; Zhao, Haocen; Ye, Zhifeng

2017-08-01

Data-fused and user-friendly design of aero-engine accessories is required because of their structural complexity and stringent reliability. This paper gives an overview of a typical aero-engine control system and the development process of key mechatronic devices used. Several essential aspects of modeling and simulation in the process are investigated. Considering the limitations of a single theoretic model, feature-based co-modeling methodology is suggested to satisfy the design requirements and compensate for diversity of component sub-models for these devices. As an example, a stepper motor controlled Fuel Metering Unit (FMU) is modeled in view of the component physical features using two different software tools. An interface is suggested to integrate the single discipline models into the synthesized one. Performance simulation of this device using the co-model and parameter optimization for its key components are discussed. Comparison between delivery testing and the simulation shows that the co-model for the FMU has a high accuracy and the absolute superiority over a single model. Together with its compatible interface with the engine mathematical model, the feature-based co-modeling methodology is proven to be an effective technical measure in the development process of the device.

Overview of NASA's space radiation research program.

PubMed

Schimmerling, Walter

2003-06-01

NASA is developing the knowledge required to accurately predict and to efficiently manage radiation risk in space. The strategy employed has three research components: (1) ground-based simulation of space radiation components to develop a science-based understanding of radiation risk; (2) space-based measurements of the radiation environment on planetary surfaces and interplanetary space, as well as use of space platforms to validate predictions; and, (3) implementation of countermeasures to mitigate risk. NASA intends to significantly expand its support of ground-based radiation research in line with completion of the Booster Applications Facility at Brookhaven National Laboratory, expected in summer of 2003. A joint research solicitation with the Department of Energy is under way and other interagency collaborations are being considered. In addition, a Space Radiation Initiative has been submitted by the Administration to Congress that would provide answers to most questions related to the International Space Station within the next 10 years.

Physiology of ageing of the musculoskeletal system.

PubMed

Boros, Katalin; Freemont, Tony

2017-04-01

This review aims to provide a summary of current concepts of ageing in relation to the musculoskeletal system, highlighting recent advances in the understanding of the mechanisms involved in the development of age-related changes in bone, skeletal muscle, chondroid and fibrous tissues. The key components of the musculoskeletal system and their functions are introduced together with a general overview of the molecular hallmarks of ageing. A brief description of the normal architecture of each of these tissue types is followed by a summary of established and developing concepts of mechanisms contributing to the age-related alterations in each. Extensive detailed description of these changes is beyond the scope of this review; instead, we aim to highlight some of the most significant processes and, where possible, the molecular changes underlying these and refer the reader to in-depth, subspecialist reviews of the individual components for further details. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

Introductory Talk: Adding Up Chemicals: Component-Based Risk Assessment of Chemical Mixturesand Primary Talk: Grouping Chemicals for Assessment and Conducting Assessments with the Hazard Index and Related Methods

EPA Science Inventory

Dr. Simmons will provide a concise overview of established and emerging methods to group chemicals for component-based mixture risk assessments. This will be followed by introduction to several important component-based methods, the Hazard Index, Target Organ Hazard Index, Multi...

An extensible circuit QED architecture for quantum computation

NASA Astrophysics Data System (ADS)

Dicarlo, Leo

Realizing a logical qubit robust to single errors in its constituent physical elements is an immediate challenge for quantum information processing platforms. A longer-term challenge will be achieving quantum fault tolerance, i.e., improving logical qubit resilience by increasing redundancy in the underlying quantum error correction code (QEC). In QuTech, we target these challenges in collaboration with industrial and academic partners. I will present the circuit QED quantum hardware, room-temperature control electronics, and software components of the complete architecture. I will show the extensibility of each component to the Surface-17 and -49 circuits needed to reach the objectives with surface-code QEC, and provide an overview of latest developments. Research funded by IARPA and Intel Corporation.

Rebuilding the foundations: major renovations to the mental health component of an undergraduate nursing curriculum.

PubMed

Spence, Deborah; Garrick, Helen; McKay, Marie

2012-10-01

Concerns relating to the adequacy of nurses' preparation for the care of people with mental illness prompted significant revision of the mental health component in a Bachelor of Health Science nursing programme in New Zealand that prepares approximately 200 students per year. Working collaboratively with clinical providers, university staff developed and introduced three courses (equivalent to 450 hours of learning) specifically focused on mental health science, inpatient practice, and primary community mental health practice. This paper provides an overview of the new courses and reports the findings of an appreciative inquiry evaluation of this curriculum innovation. © 2012 The Authors. International Journal of Mental Health Nursing © 2012 Australian College of Mental Health Nurses Inc.

[Nutritional epigenetics and epigenetic effects of human breast milk].

PubMed

Lukoyanova, O L; Borovik, T E

The article provides an overview of the current literature on nutritional epigenetics. There are currently actively studied hypothesis that nutrition especially in early life or in critical periods of the development, may have a role in modulating gene expression, and, therefore, have later effects on health in adults. Nutritional epigenetics concerns knowledge about the possible effects of nutrients on gene expression. Human breast milk is well-known for its ability in preventing necrotizing enterocolitis, infectious diseases, and also non-communicable diseases, such as obesity and related disorders. This paper discusses about presumed epigenetic effects of human breast milk and some its components. While evidence suggests that a direct relationship may exist of some components of human breast milk with epigenetic changes, the mechanisms involved are stillunclear.

Overview of Facial Plastic Surgery and Current Developments

PubMed Central

Chuang, Jessica; Barnes, Christian; Wong, Brian J. F.

2016-01-01

Facial plastic surgery is a multidisciplinary specialty largely driven by otolaryngology but includes oral maxillary surgery, dermatology, ophthalmology, and plastic surgery. It encompasses both reconstructive and cosmetic components. The scope of practice for facial plastic surgeons in the United States may include rhinoplasty, browlifts, blepharoplasty, facelifts, microvascular reconstruction of the head and neck, craniomaxillofacial trauma reconstruction, and correction of defects in the face after skin cancer resection. Facial plastic surgery also encompasses the use of injectable fillers, neural modulators (e.g., BOTOX Cosmetic, Allergan Pharmaceuticals, Westport, Ireland), lasers, and other devices aimed at rejuvenating skin. Facial plastic surgery is a constantly evolving field with continuing innovative advances in surgical techniques and cosmetic adjunctive technologies. This article aims to give an overview of the various procedures that encompass the field of facial plastic surgery and to highlight the recent advances and trends in procedures and surgical techniques. PMID:28824978

International Space Station: becoming a reality.

PubMed

David, L

1999-07-01

An overview of the development of the International Space Station (ISS) is presented starting with a brief history of space station concepts from the 1960's to the decision to build the present ISS. Other topics discussed include partnerships with Japan, Canada, ESA countries, and Russia; design changes to the ISS modules, the use of the ISS for scientific purposes and the application of space research to medicine on Earth; building ISS modules on Earth, international funding for Russian components, and the political aspects of including Russia in critical building plans. Sidebar articles examine commercialization of the ISS, multinational efforts in the design and building of the ISS, emergency transport to Earth, the use of robotics in ISS assembly, application of lessons learned from the Skylab project to the ISS, initial ISS assembly in May 1999, planned ISS science facilities, and an overview of space stations in science fiction.

An Autonomous Control System for an Intra-Vehicular Spacecraft Mobile Monitor Prototype

NASA Technical Reports Server (NTRS)

Dorais, Gregory A.; Desiano, Salvatore D.; Gawdiak, Yuri; Nicewarner, Keith

2003-01-01

This paper presents an overview of an ongoing research and development effort at the NASA Ames Research Center to create an autonomous control system for an internal spacecraft autonomous mobile monitor. It primary functions are to provide crew support and perform intra- vehicular sensing activities by autonomously navigating onboard the International Space Station. We describe the mission roles and high-level functional requirements for an autonomous mobile monitor. The mobile monitor prototypes, of which two are operational and one is actively being designed, physical test facilities used to perform ground testing, including a 3D micro-gravity test facility, and simulators are briefly described. We provide an overview of the autonomy framework and describe each of its components, including those used for automated planning, goal-oriented task execution, diagnosis, and fault recovery. A sample mission test scenario is also described.

Propulsion Controls and Diagnostics Research in Support of NASA Aeronautics and Exploration Mission Programs

NASA Technical Reports Server (NTRS)

Garg, Sanjay

2011-01-01

The Controls and Dynamics Branch (CDB) at National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) in Cleveland, Ohio, is leading and participating in various projects in partnership with other organizations within GRC and across NASA, the U.S. aerospace industry, and academia to develop advanced propulsion controls and diagnostics technologies that will help meet the challenging goals of NASA programs under the Aeronautics Research and Exploration Systems Missions. This paper provides a brief overview of the various CDB tasks in support of the NASA programs. The programmatic structure of the CDB activities is described along with a brief overview of each of the CDB tasks including research objectives, technical challenges, and recent accomplishments. These tasks include active control of propulsion system components, intelligent propulsion diagnostics and control for reliable fault identification and accommodation, distributed engine control, and investigations into unsteady propulsion systems.

Aircraft Capability Management

NASA Technical Reports Server (NTRS)

Mumaw, Randy; Feary, Mike

2018-01-01

This presentation presents an overview of work performed at NASA Ames Research Center in 2017. The work concerns the analysis of current aircraft system management displays, and the initial development of an interface for providing information about aircraft system status. The new interface proposes a shift away from current aircraft system alerting interfaces that report the status of physical components, and towards displaying the implications of degradations on mission capability. The proposed interface describes these component failures in terms of operational consequences of aircraft system degradations. The research activity was an effort to examine the utility of different representations of complex systems and operating environments to support real-time decision making of off-nominal situations. A specific focus was to develop representations that provide better integrated information to allow pilots to more easily reason about the operational consequences of the off-nominal situations. The work is also seen as a pathway to autonomy, as information is integrated and understood in a form that automated responses could be developed for the off-nominal situations in the future.

The discipline of hospital development: a conceptual framework incorporating marketing, managerial, consumer behavior, and adult learning theories.

PubMed

Shirley, S; Stampfl, R

1997-12-01

The purpose of this explanatory and prescriptive article is to identify interdisciplinary theories used by hospital development to direct its practice. The article explores, explains, and applies theories and principles from behavioral, social, and managerial disciplines. Learning, motivational, organizational, marketing, and attitudinal theories are incorporated and transformed into the fundamental components of a conceptual framework that provides an overview of the practice of hospital development. How this discipline incorporates these theories to design, explain, and prescribe the focus of its own practice is demonstrated. This interdisciplinary approach results in a framework for practice that is adaptable to changing social, cultural, economic, political, and technological environments.

Groundwater Pathway Model for the Los Alamos National Laboratory Technical Area 21, Material Disposal Area T

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stauffer, Philip H.; Levitt, Daniel G.; Miller, Terry Ann

2017-02-09

This report consists of four major sections, including this introductory section. Section 2 provides an overview of previous investigations related to the development of the current sitescale model. The methods and data used to develop the 3-D groundwater model and the techniques used to distill that model into a form suitable for use in the GoldSim models are discussed in Section 3. Section 4 presents the results of the model development effort and discusses some of the uncertainties involved. Three attachments that provide details about the components and data used in this groundwater pathway model are also included with thismore » report.« less

Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews.

PubMed

Shea, Beverley J; Grimshaw, Jeremy M; Wells, George A; Boers, Maarten; Andersson, Neil; Hamel, Candyce; Porter, Ashley C; Tugwell, Peter; Moher, David; Bouter, Lex M

2007-02-15

Our objective was to develop an instrument to assess the methodological quality of systematic reviews, building upon previous tools, empirical evidence and expert consensus. A 37-item assessment tool was formed by combining 1) the enhanced Overview Quality Assessment Questionnaire (OQAQ), 2) a checklist created by Sacks, and 3) three additional items recently judged to be of methodological importance. This tool was applied to 99 paper-based and 52 electronic systematic reviews. Exploratory factor analysis was used to identify underlying components. The results were considered by methodological experts using a nominal group technique aimed at item reduction and design of an assessment tool with face and content validity. The factor analysis identified 11 components. From each component, one item was selected by the nominal group. The resulting instrument was judged to have face and content validity. A measurement tool for the 'assessment of multiple systematic reviews' (AMSTAR) was developed. The tool consists of 11 items and has good face and content validity for measuring the methodological quality of systematic reviews. Additional studies are needed with a focus on the reproducibility and construct validity of AMSTAR, before strong recommendations can be made on its use.

Overview of the Ares I Scale Model Acoustic Test Program

NASA Technical Reports Server (NTRS)

Counter, Douglas D.; Houston, Janice D.

2011-01-01

Launch environments, such as lift-off acoustic (LOA) and ignition overpressure (IOP), are important design factors for any vehicle and are dependent upon the design of both the vehicle and the ground systems. LOA environments are used directly in the development of vehicle vibro-acoustic environments and IOP is used in the loads assessment. The NASA Constellation Program had several risks to the development of the Ares I vehicle linked to LOA. The risks included cost, schedule and technical impacts for component qualification due to high predicted vibro-acoustic environments. One solution is to mitigate the environment at the component level. However, where the environment is too severe for component survivability, reduction of the environment itself is required. The Ares I Scale Model Acoustic Test (ASMAT) program was implemented to verify the Ares I LOA and IOP environments for the vehicle and ground systems including the Mobile Launcher (ML) and tower. An additional objective was to determine the acoustic reduction for the LOA environment with an above deck water sound suppression system. ASMAT was a development test performed at the Marshall Space Flight Center (MSFC) East Test Area (ETA) Test Stand 116 (TS 116). The ASMAT program is described in this presentation.

An Overview of NASA Automotive Component Reliability Studies

NASA Technical Reports Server (NTRS)

Sampson, Michael J.

2016-01-01

The results of NASAs studies into the appropriateness of using US Automotive electronic parts in NASA spaceflight systems will be presented. The first part of the presentation provides an overview of the United States Automotive Electronics Councils AECQ standardization program, the second part provides a summary of the results of NASAs procurement and testing experiences and other lessons learned along with preliminary test results.

An Overview Of NASA Automotive Component Reliability Studies

NASA Technical Reports Server (NTRS)

Sampson, Michael J.

2016-01-01

The results of NASAs studies into the appropriateness of using US Automotive electronic parts in NASA spaceflight systems will be presented. The first part of the presentation provides an overview of the United States Automotive Electronics Councils AECQ standardization program, the second part provides a summary of the results of NASAs procurement and testing experiences and other lessons learned along with preliminary test results.

Immunofluorescence localization of dissociation supernatant and extracellular matrix components in Lytechinus pictus sectioned embryos. M.S. Thesis

NASA Technical Reports Server (NTRS)

Garciaflack, Ana Leticia

1988-01-01

Indirect immunofluorescence was used to localize specific extracellular components in embryos of the sea urchin Lytechinus pictus. Hyalin and S2 (a group of components found in the disaggregation supernatant from Strongylocentrotus purpuratus blastulae) were uniformly present at all stages (unfertilized up to 32 hr) except hyalin could not be detected at the 12 hour early blastula stage. Laminin was found in 16 cell, 32 cell, 6 hour, 18 hour, 24 hour, and 32 hour stages, with especially bright fluorescence at 18 hours. Collagen I was present at all stages (freshly fertilized up to 32 hour) except little was detected at 12 hours. Fibronectin was uniformly present in blastocoelar fibers stained with anto-collagen I and anti-fibronectin. These results were compared with those for S. purpuratus to produce an overview of the localization of specific extracellular matrix components during development of two species of sea urchins. The results set the stage for future studies that will examine the function of these components at the various developmental stages.

A new methodology for automating acoustic emission detection of metallic fatigue fractures in highly demanding aerospace environments: An overview

NASA Astrophysics Data System (ADS)

Holford, Karen M.; Eaton, Mark J.; Hensman, James J.; Pullin, Rhys; Evans, Sam L.; Dervilis, Nikolaos; Worden, Keith

2017-04-01

The acoustic emission (AE) phenomenon has many attributes that make it desirable as a structural health monitoring or non-destructive testing technique, including the capability to continuously and globally monitor large structures using a sparse sensor array and with no dependency on defect size. However, AE monitoring is yet to fulfil its true potential, due mainly to limitations in location accuracy and signal characterisation that often arise in complex structures with high levels of background noise. Furthermore, the technique has been criticised for a lack of quantitative results and the large amount of operator interpretation required during data analysis. This paper begins by introducing the challenges faced in developing an AE based structural health monitoring system and then gives a review of previous progress made in addresing these challenges. Subsequently an overview of a novel methodology for automatic detection of fatigue fractures in complex geometries and noisy environments is presented, which combines a number of signal processing techniques to address the current limitations of AE monitoring. The technique was developed for monitoring metallic landing gear components during pre-flight certification testing and results are presented from a full-scale steel landing gear component undergoing fatigue loading. Fracture onset was successfully identify automatically at 49,000 fatigue cycles prior to final failure (validated by the use of dye penetrant inspection) and the fracture position was located to within 10 mm of the actual location.

Tutorial: Radiation Effects in Electronic Systems

NASA Technical Reports Server (NTRS)

Pellish, Jonathan A.

2017-01-01

This tutorial presentation will give an overview of radiation effects in electrical, electronic, and electromechanical (EEE) components as it applies to civilian space systems of varying size and complexity. The natural space environment presents many unique threats to electronic systems regardless of where the systems operate from low-Earth orbit to interplanetary space. The presentation will cover several topics, including: an overview and introduction to the applicable space radiation environments common to a broad range of mission designs; definitions and impacts of effects due to impinging particles in the space environment e.g., total ionizing dose (TID), total non-ionizing dose (TNID), and single-event effects (SEE); and, testing for and evaluation of TID, TNID, and SEE in EEE components.

Recent developments in turbomachinery component materials and manufacturing challenges for aero engine applications

NASA Astrophysics Data System (ADS)

Srinivas, G.; Raghunandana, K.; Satish Shenoy, B.

2018-02-01

In the recent years the development of turbomachinery materials performance enhancement plays a vital role especially in aircraft air breathing engines like turbojet engine, turboprop engine, turboshaft engine and turbofan engines. Especially the transonic flow engines required highly sophisticated materials where it can sustain the entire thrust which can create by the engine. The main objective of this paper is to give an overview of the present cost-effective and technological capabilities process for turbomachinery component materials. Especially the main focus is given to study the Electro physical, Photonic additive removal process and Electro chemical process for turbomachinery parts manufacture. The aeronautical propulsion based technologies are reviewed thoroughly where in surface reliability, geometrical precession, and material removal and highly strengthened composite material deposition rates usually difficult to cut dedicated steels, Titanium and Nickel based alloys. In this paper the past aeronautical and propulsion mechanical based manufacturing technologies, current sophisticated technologies and also future challenging material processing techniques are covered. The paper also focuses on the brief description of turbomachinery components of shaping process and coating in aeromechanical applications.

Overview of studies and developments in cinematography, optoelectronic imaging, and photonics at CEA/DIF

NASA Astrophysics Data System (ADS)

Mens, Alain; Alozy, Eric; Aubert, Damien; Benier, Jacky; Bourgade, Jean-Luc; Boutin, Jean-Yves; Brunel, Patrick; Charles, Gilbert; Chollet, Clement; Desbat, Laurent; Gontier, Dominique; Jacquet, Henri-Patrick; Jasmin, Serge; Le Breton, Jean-Pierre; Marchet, Bruno; Masclet-Gobin, Isabelle; Mercier, Patrick; Millier, Philippe; Missault, Carole; Negre, Jean-Paul; Paul, Serge; Rosol, Rodolphe; Sommerlinck, Thierry; Veaux, Jacqueline; Veron, Laurent; Vincent de Araujo, Manuel; Jaanimagi, Paul; Pien, Greg

2003-07-01

This paper gives an overview of works undertaken at CEA/DIF in high speed cinematography, optoelectronic imaging and ultrafast photonics for the needs of the CEA/DAM experimental programs. We have developed a new multichannel velocimeter, and a new probe for shock breakout timing measurements in detonics experiments. A brief description and a recall of their main performances will be made. We have implemented three new optoelectronic imaging systems, in order to observe dynamic scenes in the ranges of 50 - 100 keV and 4 MeV. These systems are described, their main specifications and performances are given. Then we describe our contribution to the ICF program: after recalling the specifications of LIL plasma diagnostics, we describe the features and performances of visible streak tubes, X-ray streak tubes, visible and X-ray framing cameras and the associated systems developed to match these specifications. At last we introduce the subject of components and systems vulnerability in the LMJ target area, the principles identified to mitigate this problem and the first results of studies (image relay, response of streak tube phosphors, MCP image intensifiers and CCDs to fusion neutrons) related to this subject. Results obtained so far are presented.

WebEAV

PubMed Central

Nadkarni, Prakash M.; Brandt, Cynthia M.; Marenco, Luis

2000-01-01

The task of creating and maintaining a front end to a large institutional entity-attribute-value (EAV) database can be cumbersome when using traditional client-server technology. Switching to Web technology as a delivery vehicle solves some of these problems but introduces others. In particular, Web development environments tend to be primitive, and many features that client-server developers take for granted are missing. WebEAV is a generic framework for Web development that is intended to streamline the process of Web application development for databases having a significant EAV component. It also addresses some challenging user interface issues that arise when any complex system is created. The authors describe the architecture of WebEAV and provide an overview of its features with suitable examples. PMID:10887163

The Personal Satellite Assistant: An Internal Spacecraft Autonomous Mobile Monitor

NASA Technical Reports Server (NTRS)

Dorais, Gregory A.; Gawdiak, Yuri; Clancy, Daniel (Technical Monitor)

2002-01-01

This paper presents an overview of the research and development effort at the NASA Ames Research Center to create an internal spacecraft autonomous mobile monitor capable of performing intra-vehicular sensing activities by autonomously navigating onboard the International Space Station. We describe the capabilities, mission roles, rationale, high-level functional requirements, and design challenges for an autonomous mobile monitor. The rapid prototyping design methodology used, in which five prototypes of increasing fidelity are designed, is described as well as the status of these prototypes, of which two are operational and being tested, and one is actively being designed. The physical test facilities used to perform ground testing are briefly described, including a micro-gravity test facility that permits a prototype to propel itself in 3 dimensions with 6 degrees-of-freedom as if it were in an micro-gravity environment. We also describe an overview of the autonomy framework and its components including the software simulators used in the development process. Sample mission test scenarios are also described. The paper concludes with a discussion of future and related work followed by the summary.

An Overview of Pest Species of Bactrocera Fruit Flies (Diptera: Tephritidae) and the Integration of Biopesticides with Other Biological Approaches for Their Management with a Focus on the Pacific Region

PubMed Central

Vargas, Roger I.; Piñero, Jaime C.; Leblanc, Luc

2015-01-01

Fruit flies (Diptera: Tephritidae) are among the most economically important pest species in the world, attacking a wide range of fruits and fleshy vegetables throughout tropical and sub-tropical areas. These species are such devastating crop pests that major control and eradication programs have been developed in various parts of the world to combat them. The array of control methods includes insecticide sprays to foliage and soil, bait-sprays, male annihilation techniques, releases of sterilized flies and parasitoids, and cultural controls. During the twenty first century there has been a trend to move away from control with organophosphate insecticides (e.g., malathion, diazinon, and naled) and towards reduced risk insecticide treatments. In this article we present an overview of 73 pest species in the genus Bactrocera, examine recent developments of reduced risk technologies for their control and explore Integrated Pest Management (IPM) Programs that integrate multiple components to manage these pests in tropical and sub-tropical areas. PMID:26463186

Kaiser Permanente/Sandia National health care model. Phase I prototype final report. Part 1 - model overview

DOE Office of Scientific and Technical Information (OSTI.GOV)

Edwards, D.; Yoshimura, A.; Butler, D.

1996-11-01

This report describes the results of a Cooperative Research and Development Agreement between Sandia National Laboratories and Kaiser Permanente Southern California to develop a prototype computer model of Kaiser Permanente`s health care delivery system. As a discrete event simulation, SimHCO models for each of 100,000 patients the progression of disease, individual resource usage, and patient choices in a competitive environment. SimHCO is implemented in the object-oriented programming language C++, stressing reusable knowledge and reusable software components. The versioned implementation of SimHCO showed that the object-oriented framework allows the program to grow in complexity in an incremental way. Furthermore, timing calculationsmore » showed that SimHCO runs in a reasonable time on typical workstations, and that a second phase model will scale proportionally and run within the system constraints of contemporary computer technology. This report is published as two documents: Model Overview and Domain Analysis. A separate Kaiser-proprietary report contains the Disease and Health Care Organization Selection Models.« less

Overview of Advanced Turbine Systems Program

NASA Astrophysics Data System (ADS)

Webb, H. A.; Bajura, R. A.

The US Department of Energy initiated a program to develop advanced gas turbine systems to serve both central power and industrial power generation markets. The Advanced Turbine Systems (ATS) Program will lead to commercial offerings by the private sector by 2002. ATS will be developed to fire natural gas but will be adaptable to coal and biomass firing. The systems will be: highly efficient (15 percent improvement over today's best systems); environmentally superior (10 percent reduction in nitrogen oxides over today's best systems); and cost competitive (10 percent reduction in cost of electricity). The ATS Program has five elements. Innovative cycle development will lead to the demonstration of systems with advanced gas turbine cycles using current gas turbine technology. High temperature development will lead to the increased firing temperatures needed to achieve ATS Program efficiency goals. Ceramic component development/demonstration will expand the current DOE/CE program to demonstrate industrial-scale turbines with ceramic components. Technology base will support the overall program by conducting research and development (R&D) on generic technology issues. Coal application studies will adapt technology developed in the ATS program to coal-fired systems being developed in other DOE programs.

Oak Ridge Environmental Information System (ORIES) site workstation information packet for OREIS V1.2. Environmental Restoration Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Voorhees, L.D.; McCord, R.A.; Durfee, R.C.

1993-02-01

The OREIS site workstation information packet was developed to accompany the OREIS site workstations, which are being delivered to the Environmental Restoration programs at the five DOE-OR sites. The packet is written specifically for the Site ER program staff at each of the five Sites who have been designated the OREIS contact by their ER program manager, and is not intended for general distribution. The packet provides an overview of the components of OREIS, points to more detailed information provided in the accompanying vendor and OREIS developed manuals, and includes information on training opportunities and user support.

Oak Ridge Environmental Information System (ORIES) site workstation information packet for OREIS V1. 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Voorhees, L.D.; McCord, R.A.; Durfee, R.C.

1993-02-01

The OREIS site workstation information packet was developed to accompany the OREIS site workstations, which are being delivered to the Environmental Restoration programs at the five DOE-OR sites. The packet is written specifically for the Site ER program staff at each of the five Sites who have been designated the OREIS contact by their ER program manager, and is not intended for general distribution. The packet provides an overview of the components of OREIS, points to more detailed information provided in the accompanying vendor and OREIS developed manuals, and includes information on training opportunities and user support.

GM1 and GM2 gangliosides: recent developments.

PubMed

Bisel, Blaine; Pavone, Francesco S; Calamai, Martino

2014-03-01

GM1 and GM2 gangliosides are important components of the cell membrane and play an integral role in cell signaling and metabolism. In this conceptual overview, we discuss recent developments in our understanding of the basic biological functions of GM1 and GM2 and their involvement in several diseases. In addition to a well-established spectrum of disorders known as gangliosidoses, such as Tay-Sachs disease, more and more evidence points at an involvement of GM1 in Alzheimer's and Parkinson's diseases. New emerging methodologies spanning from single-molecule imaging in vivo to simulations in silico have complemented standard studies based on ganglioside extraction.

Security Aspects of an Enterprise-Wide Network Architecture.

ERIC Educational Resources Information Center

Loew, Robert; Stengel, Ingo; Bleimann, Udo; McDonald, Aidan

1999-01-01

Presents an overview of two projects that concern local area networks and the common point between networks as they relate to network security. Discusses security architectures based on firewall components, packet filters, application gateways, security-management components, an intranet solution, user registration by Web form, and requests for…

20 CFR 655.1300 - Overview of subpart B and definition of terms.

Code of Federal Regulations, 2010 CFR

2010-04-01

... a case-by-case basis. Such designations must be based on information provided by State agencies or... employee. Occupational Safety and Health Administration (OSHA) means the organizational component of the... Foreign Labor Certification (OFLC) means the organizational component of the ETA that provides national...

Laser program annual report, 1977. Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bender, C.F.; Jarman, B.D.

1978-07-01

An overview is given of the laser fusion program. The solid-state program covers the Shiva and Nova projects. Laser components, control systems, alignment systems, laser beam diagnostics, power conditioning, and optical components are described. The fusion experimental program concerns the diagnostics and data acquisition associated with Argus and Shiva. (MOW)

Integrated design optimization research and development in an industrial environment

NASA Astrophysics Data System (ADS)

Kumar, V.; German, Marjorie D.; Lee, S.-J.

1989-04-01

An overview is given of a design optimization project that is in progress at the GE Research and Development Center for the past few years. The objective of this project is to develop a methodology and a software system for design automation and optimization of structural/mechanical components and systems. The effort focuses on research and development issues and also on optimization applications that can be related to real-life industrial design problems. The overall technical approach is based on integration of numerical optimization techniques, finite element methods, CAE and software engineering, and artificial intelligence/expert systems (AI/ES) concepts. The role of each of these engineering technologies in the development of a unified design methodology is illustrated. A software system DESIGN-OPT has been developed for both size and shape optimization of structural components subjected to static as well as dynamic loadings. By integrating this software with an automatic mesh generator, a geometric modeler and an attribute specification computer code, a software module SHAPE-OPT has been developed for shape optimization. Details of these software packages together with their applications to some 2- and 3-dimensional design problems are described.

Integrated design optimization research and development in an industrial environment

NASA Technical Reports Server (NTRS)

Kumar, V.; German, Marjorie D.; Lee, S.-J.

1989-01-01

An overview is given of a design optimization project that is in progress at the GE Research and Development Center for the past few years. The objective of this project is to develop a methodology and a software system for design automation and optimization of structural/mechanical components and systems. The effort focuses on research and development issues and also on optimization applications that can be related to real-life industrial design problems. The overall technical approach is based on integration of numerical optimization techniques, finite element methods, CAE and software engineering, and artificial intelligence/expert systems (AI/ES) concepts. The role of each of these engineering technologies in the development of a unified design methodology is illustrated. A software system DESIGN-OPT has been developed for both size and shape optimization of structural components subjected to static as well as dynamic loadings. By integrating this software with an automatic mesh generator, a geometric modeler and an attribute specification computer code, a software module SHAPE-OPT has been developed for shape optimization. Details of these software packages together with their applications to some 2- and 3-dimensional design problems are described.

Principles of PET/MR Imaging.

PubMed

Disselhorst, Jonathan A; Bezrukov, Ilja; Kolb, Armin; Parl, Christoph; Pichler, Bernd J

2014-06-01

Hybrid PET/MR systems have rapidly progressed from the prototype stage to systems that are increasingly being used in the clinics. This review provides an overview of developments in hybrid PET/MR systems and summarizes the current state of the art in PET/MR instrumentation, correction techniques, and data analysis. The strong magnetic field requires considerable changes in the manner by which PET images are acquired and has led, among others, to the development of new PET detectors, such as silicon photomultipliers. During more than a decade of active PET/MR development, several system designs have been described. The technical background of combined PET/MR systems is explained and related challenges are discussed. The necessity for PET attenuation correction required new methods based on MR data. Therefore, an overview of recent developments in this field is provided. Furthermore, MR-based motion correction techniques for PET are discussed, as integrated PET/MR systems provide a platform for measuring motion with high temporal resolution without additional instrumentation. The MR component in PET/MR systems can provide functional information about disease processes or brain function alongside anatomic images. Against this background, we point out new opportunities for data analysis in this new field of multimodal molecular imaging. © 2014 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Overview of ISS U.S. Fire Detection and Suppression System

NASA Technical Reports Server (NTRS)

Whitaker, Alana

2003-01-01

This paper presents a general overview of the International Space Station's Fire Detection and Suppression System. The topics include: 1) Introduction to Fire Detection and Suppression (FDS); 2) Description of (FDS) Subsystems; 3) FDS System Component Location and Status; 4) FDS System Capabilities; 5) FDS Automatic and Manual Response; 6) Post Fire Atmosphere Restoration and Air Quality Assessment; and 7) FDS Research Needs. This paper is in viewgraph form.

Civil forensic psychiatry - Part 1: an overview.

PubMed

Samuels, Anthony H

2018-06-01

Objectives This paper provides an overview for general and forensic psychiatrists of the complexity and challenge of working in the civil medico-legal arena. It covers expert evidence, ethics, core concepts in civil forensic psychiatry and report writing. Conclusions Civil forensic psychiatry is an important sub-speciality component of forensic psychiatry that requires specific skills, knowledge and the ability to assist legal bodies in determining the significance of psychiatric issues.

Introducing the LHC in the classroom: an overview of education resources available

NASA Astrophysics Data System (ADS)

Wiener, Gerfried J.; Woithe, Julia; Brown, Alexander; Jende, Konrad

2016-05-01

In the context of the recent re-start of CERN’s Large Hadron Collider (LHC) and the challenge presented by unidentified falling objects (UFOs), we seek to facilitate the introduction of high energy physics in the classroom. Therefore, this paper provides an overview of the LHC and its operation, highlighting existing education resources, and linking principal components of the LHC to topics in physics curricula.

Nano-Bio Architectures: Combining Chemistry and Biology in Nanotechnology

NASA Astrophysics Data System (ADS)

Rao, Venkat

Bionanocomposite materials have tremendous potential in biomedical product research/development and applications such as medical devices, surgical implants, pharmacological product, biologics/vaccines, and advanced diagnostics tools. Bionanocomposites are a combination of biopolymeric materials combined with inert organic or inorganic materials fabricated in the nanometer scales. Biopolymers of natural origin such as proteins, polysaccharides, aliphatic polyesters, and nucleic acids serve as the core material in bionanocomposite development. This paper will provide a summary of the Nanobiocomposites and an overview of the technical challenges in the development, purification, characterization of biopolymers, and integration with other inert organic and inorganic chemical components in the fabrication of bionanocomposites. The paper will also cover the importance of the interactions between the functional components of the active bionano-structures with the inert layers in the development of biologically effective functional bionanocomposite architectures. A brief summary of the current United States and European regulations will be provided on the release of nanoparticles in the general environment and current risk assessment approaches to assess its potential adverse effects on public health and the ecosystem

Miniaturization as a key factor to the development and application of advanced metrology systems

NASA Astrophysics Data System (ADS)

Furlong, Cosme; Dobrev, Ivo; Harrington, Ellery; Hefti, Peter; Khaleghi, Morteza

2012-10-01

Recent technological advances of miniaturization engineering are enabling the realization of components and systems with unprecedented capabilities. Such capabilities, which are significantly beneficial to scientific and engineering applications, are impacting the development and the application of optical metrology systems for investigations under complex boundary, loading, and operating conditions. In this paper, and overview of metrology systems that we are developing is presented. Systems are being developed and applied to high-speed and high-resolution measurements of shape and deformations under actual operating conditions for such applications as sustainability, health, medical diagnosis, security, and urban infrastructure. Systems take advantage of recent developments in light sources and modulators, detectors, microelectromechanical (MEMS) sensors and actuators, kinematic positioners, rapid prototyping fabrication technologies, as well as software engineering.

Aviation System Analysis Capability Executive Assistant Design

NASA Technical Reports Server (NTRS)

Roberts, Eileen; Villani, James A.; Osman, Mohammed; Godso, David; King, Brent; Ricciardi, Michael

1998-01-01

In this technical document, we describe the design developed for the Aviation System Analysis Capability (ASAC) Executive Assistant (EA) Proof of Concept (POC). We describe the genesis and role of the ASAC system, discuss the objectives of the ASAC system and provide an overview of components and models within the ASAC system, and describe the design process and the results of the ASAC EA POC system design. We also describe the evaluation process and results for applicable COTS software. The document has six chapters, a bibliography, three appendices and one attachment.

A Mobile Service Robot for Life Science Laboratories

NASA Astrophysics Data System (ADS)

Schulenburg, Erik; Elkmann, Norbert; Fritzsche, Markus; Teutsch, Christian

In this paper we presents a project that is developing a mobile service robot to assist users in biological and pharmaceutical laboratories by executing routine jobs such as filling and transporting microplates. A preliminary overview of the design of the mobile platform with a robotic arm is provided. Safety aspects are one focus of the project since the robot and humans will share a common environment. Hence, several safety sensors such as laser scanners, thermographie components and artificial skin are employed. These are described along with the approaches to object recognition.

Aeronautics in NACA and NASA

NASA Technical Reports Server (NTRS)

1991-01-01

Initiated in 1915, the National Advisory Committee for Aeronautics/National Aeronautics and Space Administration (NACA/NASA) aeronautical programs have been the keystone of a sustained U.S. Government, industry, and university research effort which has been a primary factor in the development of our remarkable air transportation systems, the country's largest positive trade balance component, and the world's finest military Air Force. This overview summarizes the flow of events, and the major trends, that have led from the NACA origins to the present NASA Aeronautics program, and indicates some important directions for the years ahead.

The First Israeli Hydro-Electric Pumped Storage Power Plant Gilboa PSPP

NASA Astrophysics Data System (ADS)

Maruzewski, P., Dr.; Sautereau, T.; Sapir, Y.; Barak, H.; Hénard, F.; Blaix, J.-C.

2016-11-01

The Israeli Public Utilities Authority, PUA, decided to increase the instantaneous power available on the grid by adding Pumped Storage Power Plants, PSPP, to the existing generation capacity. PSP Investments Ltd. is a private investor that decided to develop the Gilboa PSPP. Its capacity is 300MWe. The project performance has to comply with PUA regulation for PSPP, and with all relevant Israeli laws and IECo standards. This paper itemizes an overview of the Gilboa PSPP through short summaries of units’ components from design step to manufacturing processes.

Advanced Microsystems for Automotive Applications 2005

NASA Astrophysics Data System (ADS)

Valldorf, Jürgen; Gessner, Wolfgang

Since 1995 the annual international forum on Advanced Microsystems for Automotive Applications (AMAA) has been held in Berlin. The event offers a unique opportunity for microsystems component developers, system suppliers and car manufacturers to show and to discuss competing technological approaches of microsystems based solutions in vehicles. The book accompanying the event has demonstrated to be an efficient instrument for the diffusion of new concepts and technology results. The present volume including the papers of the AMAA 2005 gives an overview on the state-of-the-art and outlines imminent and mid-term R&D perspectives.

Overview of Human Factors and Habitability at NASA

NASA Technical Reports Server (NTRS)

Connolly, Janis; Arch, M.; Kaiser, Mary

2009-01-01

This slide presentation reviews the ongoing work on human factors and habitability in the development of the Constellation Program. The focus of the work is on how equipment, spacecraft design, tools, procedures and nutrition be used to improve the health, safety and efficiency of the crewmembers. There are slides showing the components of the Constellation Program, and the conceptual designs of the Orion Crew module, the lunar lander, (i.e., Altair) the microgravity EVA suit, and the lunar surface EVA suit, the lunar rover, and the lunar surface system infrastructure.

Structure of turbulence in three-dimensional boundary layers

NASA Technical Reports Server (NTRS)

Subramanian, Chelakara S.

1993-01-01

This report provides an overview of the three dimensional turbulent boundary layer concepts and of the currently available experimental information for their turbulence modeling. It is found that more reliable turbulence data, especially of the Reynolds stress transport terms, is needed to improve the existing modeling capabilities. An experiment is proposed to study the three dimensional boundary layer formed by a 'sink flow' in a fully developed two dimensional turbulent boundary layer. Also, the mean and turbulence field measurement procedure using a three component laser Doppler velocimeter is described.

Domestic mobile satellite systems in North America

NASA Technical Reports Server (NTRS)

Wachira, Muya

1990-01-01

Telest Mobile Inc. (TMI) and the American Mobile Satellite Corporation (AMSC) are authorized to provide mobile satellite services (MSS) in Canada and the United States respectively. They are developing compatible systems and are undertaking joint specification and procurement of spacecraft and ground segment with the aim of operational systems by late 1993. Early entry (phase 1) mobile data services are offered in 1990 using space segment capacity leased from Inmarsat. Here, an overview is given of these domestic MSS with an emphasis on the TMI component of the MSAT systen.

A learning apprentice for software parts composition

NASA Technical Reports Server (NTRS)

Allen, Bradley P.; Holtzman, Peter L.

1987-01-01

An overview of the knowledge acquisition component of the Bauhaus, a prototype computer aided software engineering (CASE) workstation for the development of domain-specific automatic programming systems (D-SAPS) is given. D-SAPS use domain knowledge in the refinement of a description of an application program into a compilable implementation. The approach to the construction of D-SAPS was to automate the process of refining a description of a program, expressed in an object-oriented domain language, into a configuration of software parts that implement the behavior of the domain objects.

Mechanical Components Branch Test Facilities and Capabilities

NASA Technical Reports Server (NTRS)

Oswald, Fred B.

2004-01-01

The Mechanical Components Branch at NASA Glenn Research Center formulates, conducts, and manages research focused on propulsion systems for both present and advanced aeronautical and space vehicles. The branch is comprised of research teams that perform basic research in three areas: mechanical drives, aerospace seals, and space mechanisms. Each team has unique facilities for testing aerospace hardware and concepts. This report presents an overview of the Mechanical Components Branch test facilities.

ControlShell: A real-time software framework

NASA Technical Reports Server (NTRS)

Schneider, Stanley A.; Chen, Vincent W.; Pardo-Castellote, Gerardo

1994-01-01

The ControlShell system is a programming environment that enables the development and implementation of complex real-time software. It includes many building tools for complex systems, such as a graphical finite state machine (FSM) tool to provide strategic control. ControlShell has a component-based design, providing interface definitions and mechanisms for building real-time code modules along with providing basic data management. Some of the system-building tools incorporated in ControlShell are a graphical data flow editor, a component data requirement editor, and a state-machine editor. It also includes a distributed data flow package, an execution configuration manager, a matrix package, and an object database and dynamic binding facility. This paper presents an overview of ControlShell's architecture and examines the functions of several of its tools.

Digital video timing analyzer for the evaluation of PC-based real-time simulation systems

NASA Astrophysics Data System (ADS)

Jones, Shawn R.; Crosby, Jay L.; Terry, John E., Jr.

2009-05-01

Due to the rapid acceleration in technology and the drop in costs, the use of commercial off-the-shelf (COTS) PC-based hardware and software components for digital and hardware-in-the-loop (HWIL) simulations has increased. However, the increase in PC-based components creates new challenges for HWIL test facilities such as cost-effective hardware and software selection, system configuration and integration, performance testing, and simulation verification/validation. This paper will discuss how the Digital Video Timing Analyzer (DiViTA) installed in the Aviation and Missile Research, Development and Engineering Center (AMRDEC) provides quantitative characterization data for PC-based real-time scene generation systems. An overview of the DiViTA is provided followed by details on measurement techniques, applications, and real-world examples of system benefits.

Towards Employment: What Research Says About Support-to-Work in Relation to Psychiatric and Intellectual Disabilities.

PubMed

Lövgren, Veronica; Markström, Urban; Sauer, Lennart

2017-01-01

This article presents an overview of research about support-to-work in relation to psychiatric and intellectual disabilities. The overview shows that support-to-work services are multifaceted, and that work can be seen as a tool for individual rehabilitation or as a set of goals to achieve. Providers are presented with specific components, which are characterized by systematic, targeted, and individualized interventions. The overview illustrates a need for long-term engagement and cooperation of and between welfare services and agents within the labor market to dissolve the Gordian knot that the transition from welfare interventions to employment seems to be.

Overview of Management Systems. No. 157.

ERIC Educational Resources Information Center

Goddu, Roland

The need for organizational management is discussed, and educational management systems are examined, with attention paid to organizational components and different approaches to organizational control. (MJB)

Dance band on the Titanic: biomechanical signaling in cardiac hypertrophy.

PubMed

Sussman, Mark A; McCulloch, Andrew; Borg, Thomas K

2002-11-15

Biomechanical signaling is a complex interaction of both intracellular and extracellular components. Both passive and active components are involved in the extracellular environment to signal through specific receptors to multiple signaling pathways. This review provides an overview of extracellular matrix, specific receptors, and signaling pathways for biomechanical stimulation in cardiac hypertrophy.

Wyoming State Library Five Year Plan, 1974-1978.

ERIC Educational Resources Information Center

Wyoming State Library, Cheyenne.

An overview is presented of the Wyoming State Library Five Year Plan. The first major component deals with demographic characteristics, giving data on the State's area, population, racial characteristics, and the location of minority groups. The second main component provides a brief review of the Wyoming State Library Advisory Council and the…

Artificial regeneration: An essential component of longleaf pine ecosystem restoration

Treesearch

James P. Barnett

2000-01-01

Regenerating longleaf pine by artificial means is an essential component of restoring the ecosystem across most of its range because there are limited acres of longleaf stands remaining. Establishing longleaf pine is an early step in the ecosystem restoration process. An overview discussion of artificial regeneration techniques and related issues are presented this...

Advocacy and Age: Issues, Experiences, Strategies.

ERIC Educational Resources Information Center

Kerschner, Paul A., Ed.

This monograph seeks to bring understanding to one component of the advocacy field, that of advocacy and the aged, by overviewing this component through a series of articles. (Advocacy is an activity by which changes can be effected in a power structure to improve a subgroup's situation.) There are four parts to the document: part 1, entitled…

Exergy as a useful tool for the performance assessment of aircraft gas turbine engines: A key review

NASA Astrophysics Data System (ADS)

Şöhret, Yasin; Ekici, Selcuk; Altuntaş, Önder; Hepbasli, Arif; Karakoç, T. Hikmet

2016-05-01

It is known that aircraft gas turbine engines operate according to thermodynamic principles. Exergy is considered a very useful tool for assessing machines working on the basis of thermodynamics. In the current study, exergy-based assessment methodologies are initially explained in detail. A literature overview is then presented. According to the literature overview, turbofans may be described as the most investigated type of aircraft gas turbine engines. The combustion chamber is found to be the most irreversible component, and the gas turbine component needs less exergetic improvement compared to all other components of an aircraft gas turbine engine. Finally, the need for analyses of exergy, exergo-economic, exergo-environmental and exergo-sustainability for aircraft gas turbine engines is emphasized. A lack of agreement on exergy analysis paradigms and assumptions is noted by the authors. Exergy analyses of aircraft gas turbine engines, fed with conventional fuel as well as alternative fuel using advanced exergy analysis methodology to understand the interaction among components, are suggested to those interested in thermal engineering, aerospace engineering and environmental sciences.

Photonic Integrated Circuit (PIC) Device Structures: Background, Fabrication Ecosystem, Relevance to Space Systems Applications, and Discussion of Related Radiation Effects

NASA Technical Reports Server (NTRS)

Alt, Shannon

2016-01-01

Electronic integrated circuits are considered one of the most significant technological advances of the 20th century, with demonstrated impact in their ability to incorporate successively higher numbers transistors and construct electronic devices onto a single CMOS chip. Photonic integrated circuits (PICs) exist as the optical analog to integrated circuits; however, in place of transistors, PICs consist of numerous scaled optical components, including such "building-block" structures as waveguides, MMIs, lasers, and optical ring resonators. The ability to construct electronic and photonic components on a single microsystems platform offers transformative potential for the development of technologies in fields including communications, biomedical device development, autonomous navigation, and chemical and atmospheric sensing. Developing on-chip systems that provide new avenues for integration and replacement of bulk optical and electro-optic components also reduces size, weight, power and cost (SWaP-C) limitations, which are important in the selection of instrumentation for specific flight projects. The number of applications currently emerging for complex photonics systems-particularly in data communications-warrants additional investigations when considering reliability for space systems development. This Body of Knowledge document seeks to provide an overview of existing integrated photonics architectures; the current state of design, development, and fabrication ecosystems in the United States and Europe; and potential space applications, with emphasis given to associated radiation effects and reliability.

A technical review of cellular radio and analysis of a possible protocol

NASA Astrophysics Data System (ADS)

Reese, William D.

1992-09-01

Radio and television technology made the field of cellular radio possible. This thesis shows the development of radio and television technology from both a historical and technical aspect. A review of the important researchers and their contributions is followed by a technical explanation of the theories behind electromagnetic radiation of radio and television signals and the technology which was developed to implement such transmissions. The evolution of development which the paper outlines begins with some of the first theories about electricity and magnetism and the subsequent mathematical foundation developed to explain them. This is followed by a number of experimental and developmental researchers and their contributions. The bulk of the paper is concentrated on explaining the earliest generations of radio and all generations of television. The major components of both radio and television are described in detail along with an explanation of what they do and how they work. Such components, in many cases, found important uses in fields outside those for which they were developed. A brief overview of the regulatory environment of each technology and the U.S. and international standardization efforts is also included. Finally, the paper illustrates a modern-day application of radio technology--the cellular radio industry. A description of the components and their functions is followed by a possible cellular radio protocol and analysis.

NASA Ares I Launch Vehicle First Stage Roll Control System Cold Flow Development Test Program Overview

NASA Technical Reports Server (NTRS)

Butt, Adam; Popp, Christopher G.; Holt, Kimberly A.; Pitts, Hank M.

2010-01-01

The Ares I launch vehicle is the selected design, chosen to return humans to the moon, Mars, and beyond. It is configured in two inline stages: the First Stage is a Space Shuttle derived five-segment Solid Rocket Booster and the Upper Stage is powered by a Saturn V derived J-2X engine. During launch, roll control for the First Stage (FS) is handled by a dedicated Roll Control System (RoCS) located on the connecting Interstage. That system will provide the Ares I with the ability to counteract induced roll torque while any induced yaw or pitch moments are handled by vectoring of the booster nozzle. This paper provides an overview of NASA s Ares I FS RoCS cold flow development test program including detailed test objectives, types of tests run to meet those objectives, an overview of the results, and applicable lessons learned. The test article was built and tested at the NASA Marshall Space Flight Center in Huntsville, AL. The FS RoCS System Development Test Article (SDTA) is a full scale, flight representative water flow test article whose primary objective was to obtain fluid system performance data to evaluate integrated system level performance characteristics and verify analytical models. Development testing and model correlation was deemed necessary as there is little historical precedent for similar large flow, pulsing systems such as the FS RoCS. The cold flow development test program consisted of flight-similar tanks, pressure regulators, and thruster valves, as well as plumbing simulating flight geometries, combined with other facility grade components and structure. Orifices downstream of the thruster valves were used to simulate the pressure drop through the thrusters. Additional primary objectives of this test program were to: evaluate system surge pressure (waterhammer) characteristics due to thruster valve operation over a range of mission duty cycles at various feed system pressures, evaluate temperature transients and heat transfer in the pressurization system, including regulator blowdown and propellant ullage performance, measure system pressure drops for comparison to analysis of tubing and components, and validate system activation and re-activation procedures for the helium pressurant system. Secondary objectives included: validating system processes for loading, unloading, and purging, validating procedures and system response for multiple failure scenarios, including relief valve operation, and evaluating system performance for contingency scenarios. The test results of the cold flow development test program are essential in validating the performance and interaction of the Roll Control System and anchoring analysis tools and results to a Critical Design Review level of fidelity.

The development of a post-test diagnostic system for rocket engines

NASA Technical Reports Server (NTRS)

Zakrajsek, June F.

1991-01-01

An effort was undertaken by NASA to develop an automated post-test, post-flight diagnostic system for rocket engines. The automated system is designed to be generic and to automate the rocket engine data review process. A modular, distributed architecture with a generic software core was chosen to meet the design requirements. The diagnostic system is initially being applied to the Space Shuttle Main Engine data review process. The system modules currently under development are the session/message manager, and portions of the applications section, the component analysis section, and the intelligent knowledge server. An overview is presented of a rocket engine data review process, the design requirements and guidelines, the architecture and modules, and the projected benefits of the automated diagnostic system.

Development of high frequency pulse tube cryocoolers for space applications

NASA Astrophysics Data System (ADS)

Dang, Haizheng

2012-06-01

This paper reviews recent advances in high frequency pulse tube cryocoolers developed in SITP/CAS to provide high reliability, low-noise and long life cooling for potential space applications. The advances in understanding the cooler mechanism and minimizing irreversible losses in various components are described, which have made a great contribution to the improved efficiencies. At present, the operating temperatures cover from 30 K to 200 K and the cooling capacities vary from hundreds of milliwatts to over 20 W to meet a variety of requirements. Some typical cryocooler development programs are introduced and a brief overview of the updated data package is presented. The proposed applications, design approaches, research advances, the major problems and the efforts to overcome them are described.

Measuring symptoms as a critical component of drug development and evaluation in hematological diseases

PubMed Central

Williams, Loretta A; Yucel, Emre; Cortes, Jorge E; Cleeland, Charles S

2014-01-01

With the rapid development of new therapies for patients with hematological malignancies, there is an increasing need for patient report of symptom status during all phases of drug testing. The patient’s perspective on new treatments reflects treatment tolerability as well as symptom benefit, and may assist patients and clinicians in choosing treatments. Inclusion of patient-reported outcomes, more common in solid-tumor than hematological trials, provides early information about symptoms to guide decisions about appropriate dosing and supportive care needs. We provide a historical overview of the use of patient-reported outcomes and symptom assessment in solid-tumor and hematological drug development, and offer recommendations about methodological issues in the monitoring of symptoms in the drug development process in hematological clinical trials. PMID:24910769

The Masdar Institute solar platform: A new research facility in the UAE for development of CSP components and thermal energy storage systems

NASA Astrophysics Data System (ADS)

Calvet, Nicolas; Martins, Mathieu; Grange, Benjamin; Perez, Victor G.; Belasri, Djawed; Ali, Muhammad T.; Armstrong, Peter R.

2016-05-01

Masdar Institute established a new solar platform dedicated to research and development of concentrated solar power (CSP), and thermal energy storage systems. The facility includes among others, state of the art solar resource assessment apparatuses, a 100 kW beam down CSP plant that has been adapted to research activity, one independent 100 kW hot-oil loop, and new thermal energy storage systems. The objective of this platform is to develop cost efficient CSP solutions, promote and test these technologies in extreme desert conditions, and finally develop local expertise. The purpose of this paper is not to present experimental results, but more to give a general overview of the different capabilities of the Masdar Institute Solar Platform.

WebEAV: automatic metadata-driven generation of web interfaces to entity-attribute-value databases.

PubMed

Nadkarni, P M; Brandt, C M; Marenco, L

2000-01-01

The task of creating and maintaining a front end to a large institutional entity-attribute-value (EAV) database can be cumbersome when using traditional client-server technology. Switching to Web technology as a delivery vehicle solves some of these problems but introduces others. In particular, Web development environments tend to be primitive, and many features that client-server developers take for granted are missing. WebEAV is a generic framework for Web development that is intended to streamline the process of Web application development for databases having a significant EAV component. It also addresses some challenging user interface issues that arise when any complex system is created. The authors describe the architecture of WebEAV and provide an overview of its features with suitable examples.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karpius, Peter Joseph; Myers, Steven Charles

This presentation is a part of the DHS LSS spectroscopy course and provides an overview of the following concepts: detector system components, intrinsic and absolute efficiency, resolution and linearity, and operational issues and limits.

On the development of radiation tolerant surveillance camera from consumer-grade components

NASA Astrophysics Data System (ADS)

Klemen, Ambrožič; Luka, Snoj; Lars, Öhlin; Jan, Gunnarsson; Niklas, Barringer

2017-09-01

In this paper an overview on the process of designing a radiation tolerant surveillance camera from consumer grade components and commercially available particle shielding materials is given. This involves utilization of Monte-Carlo particle transport code MCNP6 and ENDF/B-VII.0 nuclear data libraries, as well as testing the physical electrical systems against γ radiation, utilizing JSI TRIGA mk. II fuel elements as a γ-ray sources. A new, aluminum, 20 cm × 20 cm × 30 cm irradiation facility with electrical power and signal wire guide-tube to the reactor platform, was designed and constructed and used for irradiation of large electronic and optical components assemblies with activated fuel elements. Electronic components to be used in the camera were tested against γ-radiation in an independent manner, to determine their radiation tolerance. Several camera designs were proposed and simulated using MCNP, to determine incident particle and dose attenuation factors. Data obtained from the measurements and MCNP simulations will be used to finalize the design of 3 surveillance camera models, with different radiation tolerances.

Development of a high resolution interstellar dust engineering model - overview of the project

NASA Astrophysics Data System (ADS)

Sterken, V. J.; Strub, P.; Soja, R. H.; Srama, R.; Krüger, H.; Grün, E.

2013-09-01

Beyond 3 AU heliocentric distance, the flow of interstellar dust through the solar system is a dominant component of the total dust population. The modulation of this flux with the solar cycle and the position in the solar system has been predicted by theoretical studies since the seventies. The modulation was proven to exist by matching dust trajectory simulations with real spacecraft data from Ulysses in 1998. The modulations were further analyzed and studies in detail in 2012. The current ESA interplanetary meteoroid model IMEM includes an interstellar dust component, but this component was modelled only with straight line trajectories through the solar system. For the new ESA IMEX model, a high-resolution interstellar dust component is implemented separately from a dust streams module. The dust streams module focuses on dust in streams that was released from comets (cf. Abstract R. Soja). Parallel processing techniques are used to improve computation time (cf. Abstract P. Strub). The goal is to make predictions for the interstellar dust flux as close to the Sun as 1 AU or closer, for future space mission design.

Helminths and their implication in sepsis – a new branch of their immunomodulatory behaviour?

PubMed Central

Hübner, Marc P; Layland, Laura E; Hoerauf, Achim

2013-01-01

The prevalence of autoimmune and allergic disorders has dramatically increased in developed countries, and it is believed that our ‘cleaner living’ reduces exposure to certain microorganisms and leads to deviated and/or reduced regulation of the immune system. In substantiation of this health hygiene hypothesis, multiple epidemiological studies and animal models have characterized the protective immune responses induced by helminths during auto-inflammatory disorders. The beneficial effects of such helminths, like schistosomes and filariae, are thought to lie in their immunomodulatory capacity, which can be induced by different life-cycle stages or components thereof. In addition to suppressing autoimmunity recent evidence indicates that concurrent helminth infections also counterbalance exacerbated pro-inflammatory immune responses that occur during sepsis, improving survival. As with allergy, epidemiological studies have observed a steady rise in severe sepsis cases and although this may have resulted from several factors (immunosuppressive drugs, chemotherapy, transplantation, increased awareness and increased surgical procedures), it is tempting to hypothesize that the lack of helminth infections in Western countries may have contributed to this phenomenon. This review summarizes how helminths modulate host immunity during sepsis, such as manipulating macrophage activation and provides an overview about the possible implications that may arise during overwhelming bacterial co-infections. This well written review gives a comprehensive overview on the immunopathology of sepsis and the modulation of immune responses by helminths. It provides evidence that helminths or components thereof may improve the outcome of severe infections. This will allow the development of therapeutic strategies to fight infections and sepsis. PMID:23929557

Environmental Barrier Coatings for Ceramic Matrix Composites - An Overview

NASA Technical Reports Server (NTRS)

Lee, Kang; van Roode, Mark; Kashyap, Tania; Zhu, Dongming; Wiesner, Valerie

2017-01-01

SiC/SiC Ceramic Matrix Composites (CMCs) are increasingly being considered as structural materials for advanced power generation equipment because of their light weight, higher temperature capability, and oxidation resistance. Limitations of SiC/SiC CMCs include surface recession and component cracking and associated chemical changes in the CMC. The solutions pursued to improve the life of SiC/SiC CMCs include the incorporation of coating systems that provide surface protection, which has become known as an Environmental Barrier Coating (EBC). The development of EBCs for the protection of gas turbine hot section CMC components was a continuation of coating development work for corrosion protection of silicon-based monolithics. Work on EBC development for SiC/SiC CMCs has been ongoing at several national laboratories and the original gas turbine equipment manufacturers. The work includes extensive laboratory, rig and engine testing, including testing of EBC coated SiC/SiC CMCs in actual field applications. Another EBC degradation issue which is especially critical for CMC components used in aircraft engines is the degradation from glassy deposits of calcium-magnesium-aluminosilicate (CMAS) with other minor oxides. This paper addresses the need for and properties of external coatings on SiC/SiC CMCs to extend their useful life in service and the retention of their properties.

An overview of aerospace gas turbine technology of relevance to the development of the automotive gas turbine engine

NASA Technical Reports Server (NTRS)

Evans, D. G.; Miller, T. J.

1978-01-01

The NASA-Lewis Research Center (LeRC) has conducted, and has sponsored with industry and universities, extensive research into many of the technology areas related to gas turbine propulsion systems. This aerospace-related technology has been developed at both the component and systems level, and may have significant potential for application to the automotive gas turbine engine. This paper summarizes this technology and lists the associated references. The technology areas are system steady-state and transient performance prediction techniques, compressor and turbine design and performance prediction programs and effects of geometry, combustor technology and advanced concepts, and ceramic coatings and materials technology.

Wnt signaling in cancer

PubMed Central

Zhan, T; Rindtorff, N; Boutros, M

2017-01-01

Wnt signaling is one of the key cascades regulating development and stemness, and has also been tightly associated with cancer. The role of Wnt signaling in carcinogenesis has most prominently been described for colorectal cancer, but aberrant Wnt signaling is observed in many more cancer entities. Here, we review current insights into novel components of Wnt pathways and describe their impact on cancer development. Furthermore, we highlight expanding functions of Wnt signaling for both solid and liquid tumors. We also describe current findings how Wnt signaling affects maintenance of cancer stem cells, metastasis and immune control. Finally, we provide an overview of current strategies to antagonize Wnt signaling in cancer and challenges that are associated with such approaches. PMID:27617575

Nanotechnology in the development of novel functional foods or their package. An overview based in patent analysis.

PubMed

Pérez-Esteve, Edgar; Bernardos, Andrea; Martínez-Máñez, Ramón; Barat, José M

2013-04-01

In recent years nanotechnology has become a significant component in food industry. It is present in all food chain steps, from the design of new ingredients or additives, to the most modern systems of food quality methods or packaging, demonstrating the great potential of this new technology in a sector as traditional as food. However, while interest by industry in nanotechnology increases, the rejection by consumers, concerned about the potential risk, does too. The aim of this review is to evaluate the development of food nanotechnology by means of a patent analysis, highlighting current applications of nanotechnology along the whole food chain and contextualizing this evolution in the social scene.

Gen IV Materials Handbook Functionalities and Operation (4A) Handbook Version 4.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ren, Weiju

2013-09-01

This document is prepared for navigation and operation of the Gen IV Materials Handbook, with architecture description and new user access initiation instructions. Development rationale and history of the Handbook is summarized. The major development aspects, architecture, and design principles of the Handbook are briefly introduced to provide an overview of its past evolution and future prospects. Detailed instructions are given with examples for navigating the constructed Handbook components and using the main functionalities. Procedures are provided in a step-by-step fashion for Data Upload Managers to upload reports and data files, as well as for new users to initiate Handbookmore » access.« less

An Overview of the Distributed Space Exploration Simulation (DSES) Project

NASA Technical Reports Server (NTRS)

Crues, Edwin Z.; Chung, Victoria I.; Blum, Michael G.; Bowman, James D.

2007-01-01

This paper describes the Distributed Space Exploration Simulation (DSES) Project, a research and development collaboration between NASA centers which investigates technologies, and processes related to integrated, distributed simulation of complex space systems in support of NASA's Exploration Initiative. In particular, it describes the three major components of DSES: network infrastructure, software infrastructure and simulation development. With regard to network infrastructure, DSES is developing a Distributed Simulation Network for use by all NASA centers. With regard to software, DSES is developing software models, tools and procedures that streamline distributed simulation development and provide an interoperable infrastructure for agency-wide integrated simulation. Finally, with regard to simulation development, DSES is developing an integrated end-to-end simulation capability to support NASA development of new exploration spacecraft and missions. This paper presents the current status and plans for these three areas, including examples of specific simulations.

Observing System Simulation Experiments

NASA Technical Reports Server (NTRS)

Prive, Nikki

2015-01-01

This presentation gives an overview of Observing System Simulation Experiments (OSSEs). The components of an OSSE are described, along with discussion of the process for validating, calibrating, and performing experiments. a.

Integrating planning and reaction: A preliminary report

NASA Technical Reports Server (NTRS)

Bresina, John L.; Drummond, Mark

1990-01-01

The Entropy Reduction Engine architecture for integrating planning, scheduling, and control is examined. The architecture is motivated through a NASA mission scenario and a brief list of design goals. An overview is presented of the Entropy Reduction Engine architecture by describing its major components, their interactions, and the way in which these interacting components satisfy the design goals.

A component-based, integrated spatially distributed hydrologic/water quality model: AgroEcoSystem-Watershed (AgES-W) overview and application

USDA-ARS?s Scientific Manuscript database

AgroEcoSystem-Watershed (AgES-W) is a modular, Java-based spatially distributed model which implements hydrologic/water quality simulation components. The AgES-W model was previously evaluated for streamflow and recently has been enhanced with the addition of nitrogen (N) and sediment modeling compo...

The Virtual Environment for Reactor Applications (VERA): Design and architecture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Turner, John A., E-mail: turnerja@ornl.gov; Clarno, Kevin; Sieger, Matt

VERA, the Virtual Environment for Reactor Applications, is the system of physics capabilities being developed and deployed by the Consortium for Advanced Simulation of Light Water Reactors (CASL). CASL was established for the modeling and simulation of commercial nuclear reactors. VERA consists of integrating and interfacing software together with a suite of physics components adapted and/or refactored to simulate relevant physical phenomena in a coupled manner. VERA also includes the software development environment and computational infrastructure needed for these components to be effectively used. We describe the architecture of VERA from both software and numerical perspectives, along with the goalsmore » and constraints that drove major design decisions, and their implications. We explain why VERA is an environment rather than a framework or toolkit, why these distinctions are relevant (particularly for coupled physics applications), and provide an overview of results that demonstrate the use of VERA tools for a variety of challenging applications within the nuclear industry.« less

Developing a neurosurgical simulation-based educational curriculum: an overview.

PubMed

Harrop, James; Lobel, Darlene A; Bendok, Bernard; Sharan, Ashwini; Rezai, Ali R

2013-10-01

The science of medicine has undergone rapid advancement and expansion as a result of significant technological innovations, and this has affected the training of neurosurgical residents. To develop a simulation-based neurosurgical educational curriculum to improve resident education. The Congress of Neurological Surgeons established a Simulation Committee to explore the use of this technology in maximizing neurosurgical education. Simulators were incorporated into an educational curriculum with both a didactic and a technical component. The simulators and didactic portions were validated with objective pretests and posttests. The Simulator Committee has continued to expand the use of simulators in neurosurgical education and has organized several practical courses. The simulator use continues to expand into vasculature, spinal, and cranial modules. Each module has independently shown improved training scores in both didactic and technical skills. The Congress of Neurological Surgeons has successfully incorporated simulation into an educational curriculum with both didactic and technical components. This appears to be a powerful educational tool, and its uses are being further expanded.

Biomimetic and bioactive nanofibrous scaffolds from electrospun composite nanofibers

PubMed Central

Zhang, YZ; Su, B; Venugopal, J; Ramakrishna, S; Lim, CT

2007-01-01

Electrospinning is an enabling technology that can architecturally (in terms of geometry, morphology or topography) and biochemically fabricate engineered cellular scaffolds that mimic the native extracellular matrix (ECM). This is especially important and forms one of the essential paradigms in the area of tissue engineering. While biomimesis of the physical dimensions of native ECM’s major constituents (eg, collagen) is no longer a fabrication-related challenge in tissue engineering research, conveying bioactivity to electrospun nanofibrous structures will determine the efficiency of utilizing electrospun nanofibers for regenerating biologically functional tissues. This can certainly be achieved through developing composite nanofibers. This article gives a brief overview on the current development and application status of employing electrospun composite nanofibers for constructing biomimetic and bioactive tissue scaffolds. Considering that composites consist of at least two material components and phases, this review details three different configurations of nanofibrous composite structures by using hybridizing basic binary material systems as example. These are components blended composite nanofiber, core-shell structured composite nanofiber, and nanofibrous mingled structure. PMID:18203429

Handheld emissions detector (HED): overview and development

NASA Astrophysics Data System (ADS)

Valentino, George J.; Schimmel, David

2009-05-01

Nova Engineering, Cincinnati OH, a division of L-3 Communications (L-3 Nova), under the sponsorship of Program Manager Soldier Warrior (PM-SWAR), Fort Belvoir, VA, has developed a Soldier portable, light-weight, hand-held, geolocation sensor and processing system called the Handheld Emissions Detector (HED). The HED is a broadband custom receiver and processor that allows the user to easily sense, direction find, and locate a broad range of emitters in the user's surrounding area. Now in its second design iteration, the HED incorporates a set of COTS components that are complemented with L-3 Nova custom RF, power, digital, and mechanical components, plus custom embedded and application software. The HED user interfaces are designed to provide complex information in a readily-understandable form, thereby providing actionable results for operators. This paper provides, where possible, the top-level characteristics of the HED as well as the rationale behind its design philosophy along with its applications in both DOD and Commercial markets.

Dynamic Analysis With Stress Mode Animation by the Integrated Force Method

NASA Technical Reports Server (NTRS)

Patnaik, Surya N.; Coroneos, Rula M.; Hopkins, Dale A.

1997-01-01

Dynamic animation of stresses and displacements, which complement each other, can be a useful tool in the analysis and design of structural components. At the present time only displacement-mode animation is available through the popular stiffness formulation. This paper attempts to complete this valuable visualization tool by augmenting the existing art with stress mode animation. The reformulated method of forces, which in the literature is known as the integrated force method (IFM), became the analyzer of choice for the development of stress mode animation because stresses are the primary unknowns of its dynamic analysis. Animation of stresses and displacements, which have been developed successfully through the IFM analyzers, is illustrated in several examples along with a brief introduction to IFM dynamic analysis. The usefulness of animation in design optimization is illustrated considering the spacer structure component of the International Space Station as an example. An overview of the integrated force method analysis code (IFM/ANALYZERS) is provided in the appendix.

Collision of Physics and Software in the Monte Carlo Application Toolkit (MCATK)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sweezy, Jeremy Ed

2016-01-21

The topic is presented in a series of slides organized as follows: MCATK overview, development strategy, available algorithms, problem modeling (sources, geometry, data, tallies), parallelism, miscellaneous tools/features, example MCATK application, recent areas of research, and summary and future work. MCATK is a C++ component-based Monte Carlo neutron-gamma transport software library with continuous energy neutron and photon transport. Designed to build specialized applications and to provide new functionality in existing general-purpose Monte Carlo codes like MCNP, it reads ACE formatted nuclear data generated by NJOY. The motivation behind MCATK was to reduce costs. MCATK physics involves continuous energy neutron & gammamore » transport with multi-temperature treatment, static eigenvalue (k eff and α) algorithms, time-dependent algorithm, and fission chain algorithms. MCATK geometry includes mesh geometries and solid body geometries. MCATK provides verified, unit-test Monte Carlo components, flexibility in Monte Carlo application development, and numerous tools such as geometry and cross section plotters.« less

Bovine placenta: a review on morphology, components, and defects from terminology and clinical perspectives.

PubMed

Peter, Augustine T

2013-10-15

The bovine placenta has been the subject of many studies. Concurrently, several specialized terms have been developed to describe its development, morphology, components, function, and pathology. Many of these terms are simple, some are difficult to understand and use, and others are antiquated and may not be scientifically accurate. Defining and adopting terminology for the bovine placenta that is clear, precise and understandable, and available in a single source is expected to facilitate exchange of clinical and research information. This review presents a brief overview of the current knowledge regarding the bovine placenta and attempts to define terms. In this process, conventional terminology is presented, and contemporary and novel terms are proposed from a biological perspective. For example, use of terms such as syndesmochorial, retained placenta, and large offspring syndrome should be revisited. Furthermore, the clinical relevance of the structure and function of the bovine placenta is reviewed. Finally, terms discussed in this review are summarized (in table format). Copyright © 2013 Elsevier Inc. All rights reserved.

2012 Workplace and Gender Relations Survey of Reserve Component Members: Survey Note and Briefing

DTIC Science & Technology

2013-05-08

to be a statistically significant difference at the .05 leve l of significance. Overview The abi li ty to calculate annual prevalence rates is a...understand that to be a statistically significant difference at the .05 level of significance. Overview The ability to calculate annual prevalence...statistically significant differences for women or men in the overall rate between 2008 and 2012. Of the 2.8% of women who experienced UMAN

Overview of NASA Technology Development for In-Situ Resource Utilization (ISRU)

NASA Technical Reports Server (NTRS)

Linne, Diane L.; Sanders, Gerald B.; Starr, Stanley O.; Eisenman, David J.; Suzuki, Nantel H.; Anderson, Molly S.; O'Malley, Terrence F.; Araghi, Koorosh R.

2017-01-01

In-Situ Resource Utilization (ISRU) encompasses a broad range of systems that enable the production and use of extraterrestrial resources in support of future exploration missions. It has the potential to greatly reduce the dependency on resources transported from Earth (e.g., propellants, life support consumables), thereby significantly improving the ability to conduct future missions. Recognizing the critical importance of ISRU for the future, NASA is currently conducting technology development projects in two of its four mission directorates. The Advanced Exploration Systems Division in the Agency's Human Exploration and Operations Mission Directorate has initiated a new project for ISRU Technology focused on component, subsystem, and system maturation in the areas of water volatiles resource acquisition, and water volatiles and atmospheric processing into propellants and other consumable products. The Space Technology Mission Directorate is supporting development of ISRU component technologies in the areas of Mars atmosphere acquisition, including dust management, and oxygen production from Mars atmosphere for propellant and life support consumables. Together, these two coordinated projects are working towards a common goal of demonstrating ISRU technology and systems in preparation for future flight applications.

Overview of the DAEDALOS project

NASA Astrophysics Data System (ADS)

Bisagni, Chiara

2015-10-01

The "Dynamics in Aircraft Engineering Design and Analysis for Light Optimized Structures" (DAEDALOS) project aimed to develop methods and procedures to determine dynamic loads by considering the effects of dynamic buckling, material damping and mechanical hysteresis during aircraft service. Advanced analysis and design principles were assessed with the scope of partly removing the uncertainty and the conservatism of today's design and certification procedures. To reach these objectives a DAEDALOS aircraft model representing a mid-size business jet was developed. Analysis and in-depth investigation of the dynamic response were carried out on full finite element models and on hybrid models. Material damping was experimentally evaluated, and different methods for damping evaluation were developed, implemented in finite element codes and experimentally validated. They include a strain energy method, a quasi-linear viscoelastic material model, and a generalized Maxwell viscous material damping. Panels and shells representative of typical components of the DAEDALOS aircraft model were experimentally tested subjected to static as well as dynamic loads. Composite and metallic components of the aircraft model were investigated to evaluate the benefit in terms of weight saving.

A developmental perspective on the neural bases of human empathy.

PubMed

Tousignant, Béatrice; Eugène, Fanny; Jackson, Philip L

2017-08-01

While empathy has been widely studied in philosophical and psychological literatures, recent advances in social neuroscience have shed light on the neural correlates of this complex interpersonal phenomenon. In this review, we provide an overview of brain imaging studies that have investigated the neural substrates of human empathy. Based on existing models of the functional architecture of empathy, we review evidence of the neural underpinnings of each main component, as well as their development from infancy. Although early precursors of affective sharing and self-other distinction appear to be present from birth, recent findings also suggest that even higher-order components of empathy such as perspective-taking and emotion regulation demonstrate signs of development during infancy. This merging of developmental and social neuroscience literature thus supports the view that ontogenic development of empathy is rooted in early infancy, well before the emergence of verbal abilities. With age, the refinement of top-down mechanisms may foster more appropriate empathic responses, thus promoting greater altruistic motivation and prosocial behaviors. Copyright © 2016 Elsevier Inc. All rights reserved.

The catalyst layer and its dimensionality - A look into its ingredients and how to characterize their effects

NASA Astrophysics Data System (ADS)

Zamel, Nada

2016-03-01

Development of polymer electrolyte membrane (PEM) fuel cells throughout the years is established through its component optimization. This is especially true of its catalyst layer, where structuring of the layer has led to many breakthroughs. The catalyst layer acts as the heart of the cell, where it controls the half-cell reactions and their products. The complex nature of various transport phenomena simultaneously taking place in the layer requires the layer to be heterogeneous in structure. Hence, a delicate balance of the layer's ingredients, coupled with the understanding of the ingredients' interaction, is required. State-of-the-art catalyst layers are composed of a catalyst, its support, a solvent and a binder. Changes in the morphology, structure or material of any of these components ultimately affects the layer's activity and durability. In this review paper, we provide an overview of the various works tailored to understand how each component in the catalyst's ink affects the stability and life-time of the layer.

Laser Science & Technology Program Annual Report - 2000

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, H-L

2001-03-20

The Laser Science and Technology (LS&T) Program Annual Report 2001 provides documentation of the achievements of the LLNL LS&T Program during the April 2001 to March 2002 period using three formats: (1) an Overview that is a narrative summary of important results for the year; (2) brief summaries of research and development activity highlights within the four Program elements: Advanced Lasers and Components (AL&C), Laser Optics and Materials (LO&M), Short Pulse Laser Applications and Technologies (SPLAT), and High-Energy Laser System and Tests (HELST); and (3) a compilation of selected articles and technical reports published in reputable scientific or technology journalsmore » in this period. All three elements (Annual Overview, Activity Highlights, and Technical Reports) are also on the Web: http://laser.llnl.gov/lasers/pubs/icfq.html. The underlying mission for the LS&T Program is to develop advanced lasers, optics, and materials technologies and applications to solve problems and create new capabilities of importance to the Laboratory and the nation. This mission statement has been our guide for defining work appropriate for our Program. A major new focus of LS&T beginning this past year has been the development of high peak power short-pulse capability for the National Ignition Facility (NIF). LS&T is committed to this activity.« less

A Review of Safety and Design Requirements of the Artificial Pancreas.

PubMed

Blauw, Helga; Keith-Hynes, Patrick; Koops, Robin; DeVries, J Hans

2016-11-01

As clinical studies with artificial pancreas systems for automated blood glucose control in patients with type 1 diabetes move to unsupervised real-life settings, product development will be a focus of companies over the coming years. Directions or requirements regarding safety in the design of an artificial pancreas are, however, lacking. This review aims to provide an overview and discussion of safety and design requirements of the artificial pancreas. We performed a structured literature search based on three search components-type 1 diabetes, artificial pancreas, and safety or design-and extended the discussion with our own experiences in developing artificial pancreas systems. The main hazards of the artificial pancreas are over- and under-dosing of insulin and, in case of a bi-hormonal system, of glucagon or other hormones. For each component of an artificial pancreas and for the complete system we identified safety issues related to these hazards and proposed control measures. Prerequisites that enable the control algorithms to provide safe closed-loop control are accurate and reliable input of glucose values, assured hormone delivery and an efficient user interface. In addition, the system configuration has important implications for safety, as close cooperation and data exchange between the different components is essential.

Overview of the NASA Subsonic Rotary Wing Aeronautics Research Program in Rotorcraft Crashworthiness

NASA Technical Reports Server (NTRS)

Jackson, Karen E.; Kellas, Sotiris; Fuchs, Yvonne T.

2009-01-01

This paper provides an overview of rotorcraft crashworthiness research being conducted at NASA Langley Research Center under sponsorship of the Subsonic Rotary Wing (SRW) Aeronautics Program. The research is focused in two areas: development of an externally deployable energy attenuating concept and improved prediction of rotorcraft crashworthiness. The deployable energy absorber (DEA) is a composite honeycomb structure, with a unique flexible hinge design that allows the honeycomb to be packaged and remain flat until needed for deployment. The capabilities of the DEA have been demonstrated through component crush tests and vertical drop tests of a retrofitted fuselage section onto different surfaces or terrain. The research on improved prediction of rotorcraft crashworthiness is focused in several areas including simulating occupant responses and injury risk assessment, predicting multi-terrain impact, and utilizing probabilistic analysis methods. A final task is to perform a system-integrated simulation of a full-scale helicopter crash test onto a rigid surface. A brief description of each research task is provided along with a summary of recent accomplishments.

Overview of the NASA Subsonic Rotary Wing Aeronautics Research Program in Rotorcraft Crashworthiness

NASA Technical Reports Server (NTRS)

Jackson, Karen E.; Fuchs, Yvonne T.; Kellas, Sotiris

2008-01-01

This paper provides an overview of rotorcraft crashworthiness research being conducted at NASA Langley Research Center under sponsorship of the Subsonic Rotary Wing (SRW) Aeronautics Program. The research is focused in two areas: development of an externally deployable energy attenuating concept and improved prediction of rotorcraft crashworthiness. The deployable energy absorber (DEA) is a composite honeycomb structure, with a unique flexible hinge design that allows the honeycomb to be packaged and remain flat until needed for deployment. The capabilities of the DEA have been demonstrated through component crush tests and vertical drop tests of a retrofitted fuselage section onto different surfaces or terrain. The research on improved prediction of rotorcraft crashworthiness is focused in several areas including simulating occupant responses and injury risk assessment, predicting multi-terrain impact, and utilizing probabilistic analysis methods. A final task is to perform a system-integrated simulation of a full-scale helicopter crash test onto a rigid surface. A brief description of each research task is provided along with a summary of recent accomplishments.

MTI science, data products, and ground-data processing overview

NASA Astrophysics Data System (ADS)

Szymanski, John J.; Atkins, William H.; Balick, Lee K.; Borel, Christoph C.; Clodius, William B.; Christensen, R. Wynn; Davis, Anthony B.; Echohawk, J. C.; Galbraith, Amy E.; Hirsch, Karen L.; Krone, James B.; Little, Cynthia K.; McLachlan, Peter M.; Morrison, Aaron; Pollock, Kimberly A.; Pope, Paul A.; Novak, Curtis; Ramsey, Keri A.; Riddle, Emily E.; Rohde, Charles A.; Roussel-Dupre, Diane C.; Smith, Barham W.; Smith, Kathy; Starkovich, Kim; Theiler, James P.; Weber, Paul G.

2001-08-01

The mission of the Multispectral Thermal Imager (MTI) satellite is to demonstrate the efficacy of highly accurate multispectral imaging for passive characterization of urban and industrial areas, as well as sites of environmental interest. The satellite makes top-of-atmosphere radiance measurements that are subsequently processed into estimates of surface properties such as vegetation health, temperatures, material composition and others. The MTI satellite also provides simultaneous data for atmospheric characterization at high spatial resolution. To utilize these data the MTI science program has several coordinated components, including modeling, comprehensive ground-truth measurements, image acquisition planning, data processing and data interpretation and analysis. Algorithms have been developed to retrieve a multitude of physical quantities and these algorithms are integrated in a processing pipeline architecture that emphasizes automation, flexibility and programmability. In addition, the MTI science team has produced detailed site, system and atmospheric models to aid in system design and data analysis. This paper provides an overview of the MTI research objectives, data products and ground data processing.

Overview of the Nasa/science Mission Directorate University Student Instrument Project (usip)

NASA Astrophysics Data System (ADS)

Pierce, D. L.

2016-12-01

These are incredible times of space and Earth science discovery related to the Earth system, our Sun, the planets, and the universe. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) provides authentic student-led hands-on flight research projects as a component part of the NASA's science program. The goal of the Undergraduate Student Instrument Project (USIP) is to enable student-led scientific and technology investigations, while also providing crucial hands-on training opportunities for the Nation's future researchers. SMD, working with NASA's Office of Education (OE), the Space Technology Mission Directorate (STMD) and its Centers (GSFC/WFF and AFRC), is actively advancing the vision for student flight research using NASA's suborbital and small spacecraft platforms. Recently proposed and selected USIP projects will open up opportunities for undergraduate researchers in conducting science and developing space technologies. The paper will present an overview of USIP, results of USIP-I, and the status of current USIP-II projects that NASA is sponsoring and expects to fly in the near future.

Service-Learning in Undergraduate Nursing Education: Where is the Reflection?

PubMed

Brown, Janet M; Schmidt, Nola A

2016-01-01

Service-Learning is recognized as a valuable pedagogy that involves experiential learning, reflection, and reciprocal learning. Reflection is a critical component because it assists students to develop critical thinking and social awareness as they reflect upon their experiential learning with community partners. Although there is a proliferation of literature about service-learning, upon closer examination, it is apparent that some authors do not place emphasis on reflection when reporting on service-learning projects. This begs the question, "Where is the reflection?" The purpose of this article is to provide an overview and describe misrepresentations and exemplars of service-learning. After providing an overview of service-learning, examples of how service-learning is misrepresented in the literature are discussed. Exemplars of service-learning are also cited. Calling attention to how service-learning is reported in the literature will increase awareness about the need to critically evaluate articles for evidence of reflection. Copyright © 2016 Elsevier Inc. All rights reserved.

NASA Langley and NLR Research of Distributed Air/Ground Traffic Management

NASA Technical Reports Server (NTRS)

Ballin, Mark G.; Hoekstra, Jacco M.; Wing, David J.; Lohr, Gary W.

2002-01-01

Distributed Air/Ground Traffic Management (DAG-TM) is a concept of future air traffic operations that proposes to distribute information, decision-making authority, and responsibility among flight crews, the air traffic service provider, and aeronautical operational control organizations. This paper provides an overview and status of DAG-TM research at NASA Langley Research Center and the National Aerospace Laboratory of The Netherlands. Specific objectives of the research are to evaluate the technical and operational feasibility of the autonomous airborne component of DAG-TM, which is founded on the operational paradigm of free flight. The paper includes an overview of research approaches, the airborne technologies under development, and a summary of experimental investigations and findings to date. Although research is not yet complete, these findings indicate that free flight is feasible and will significantly enhance system capacity and safety. While free flight cannot alone resolve the complex issues faced by those modernizing the global airspace, it should be considered an essential part of a comprehensive air traffic management modernization activity.

Recollecting, recognizing, and other acts of remembering: an overview of human memory.

PubMed

LaVoie, Donna J; Cobia, Derin J

2007-09-01

The question of whether memory is important to human existence is simple to answer: life without memory would be devoid of any meaning. The question of what memory is, however, is much more difficult to answer. The main purpose of this article is to provide an overview of memory function, by drawing distinctions between different memory systems, specifically declarative (ie, conscious) versus nondeclarative (ie, nonconscious) memory systems. To distinguish between these larger systems and their various components, we include discussion of deficits in memory that occur as a consequence of brain injury and normative aging processes. Included in these descriptions is discussion of the neuroanatomical correlates of each memory component described to illustrate the importance of particular brain regions to different aspects of memory function.

Performance Validation Approach for the GTX Air-Breathing Launch Vehicle

NASA Technical Reports Server (NTRS)

Trefny, Charles J.; Roche, Joseph M.

2002-01-01

The primary objective of the GTX effort is to determine whether or not air-breathing propulsion can enable a launch vehicle to achieve orbit in a single stage. Structural weight, vehicle aerodynamics, and propulsion performance must be accurately known over the entire flight trajectory in order to make a credible assessment. Structural, aerodynamic, and propulsion parameters are strongly interdependent, which necessitates a system approach to design, evaluation, and optimization of a single-stage-to-orbit concept. The GTX reference vehicle serves this purpose, by allowing design, development, and validation of components and subsystems in a system context. The reference vehicle configuration (including propulsion) was carefully chosen so as to provide high potential for structural and volumetric efficiency, and to allow the high specific impulse of air-breathing propulsion cycles to be exploited. Minor evolution of the configuration has occurred as analytical and experimental results have become available. With this development process comes increasing validation of the weight and performance levels used in system performance determination. This paper presents an overview of the GTX reference vehicle and the approach to its performance validation. Subscale test rigs and numerical studies used to develop and validate component performance levels and unit structural weights are outlined. The sensitivity of the equivalent, effective specific impulse to key propulsion component efficiencies is presented. The role of flight demonstration in development and validation is discussed.

Energy efficient engine: Turbine intermediate case and low-pressure turbine component test hardware detailed design report

NASA Technical Reports Server (NTRS)

Leach, K.; Thulin, R. D.; Howe, D. C.

1982-01-01

A four stage, low pressure turbine component has been designed to power the fan and low pressure compressor system in the Energy Efficient Engine. Designs for a turbine intermediate case and an exit guide vane assembly also have been established. The components incorporate numerous technology features to enhance efficiency, durability, and performance retention. These designs reflect a positive step towards improving engine fuel efficiency on a component level. The aerodynamic and thermal/mechanical designs of the intermediate case and low pressure turbine components are presented and described. An overview of the predicted performance of the various component designs is given.

An overview of fatigue failures at the Rocky Flats Wind System Test Center

NASA Technical Reports Server (NTRS)

Waldon, C. A.

1981-01-01

Potential small wind energy conversion (SWECS) design problems were identified to improve product quality and reliability. Mass produced components such as gearboxes, generators, bearings, etc., are generally reliable due to their widespread uniform use in other industries. The likelihood of failure increases, though, in the interfacing of these components and in SWECS components designed for a specific system use. Problems relating to the structural integrity of such components are discussed and analyzed with techniques currently used in quality assurance programs in other manufacturing industries.

NASA Glenn Research Center UEET (Ultra-Efficient Engine Technology) Program: Agenda and Abstracts

NASA Technical Reports Server (NTRS)

Manthey, Lri

2001-01-01

Topics discussed include: UEET Overview; Technology Benefits; Emissions Overview; P&W Low Emissions Combustor Development; GE Low Emissions Combustor Development; Rolls-Royce Low Emissions Combustor Development; Honeywell Low Emissions Combustor Development; NASA Multipoint LDI Development; Stanford Activities In Concepts for Advanced Gas Turbine Combustors; Large Eddy Simulation (LES) of Gas Turbine Combustion; NASA National Combustion Code Simulations; Materials Overview; Thermal Barrier Coatings for Airfoil Applications; Disk Alloy Development; Turbine Blade Alloy; Ceramic Matrix Composite (CMC) Materials Development; Ceramic Matrix Composite (CMC) Materials Characterization; Environmental Barrier Coatings (EBC) for Ceramic Matrix Composite (CMC) Materials; Ceramic Matrix Composite Vane Rig Testing and Design; Ultra-High Temperature Ceramic (UHTC) Development; Lightweight Structures; NPARC Alliance; Technology Transfer and Commercialization; and Turbomachinery Overview; etc.

Overview of Development and Formulation of ¹⁷⁷Lu-DOTA-TATE for PRRT.

PubMed

Breeman, Wouter A P; Chan, Ho Sze; de Zanger, Rory M S; Konijnenberg, Mark K; de Blois, Erik

2016-01-01

Peptide receptor radionuclide therapy (PRRT) using radiolabeled somatostatin analogs has become an established procedure for the treatment of patients suffering from inoperable neuroendocrine cancers over-expressing somatostatin receptors. Success of PRRT depends on the availability of the radiolabeled peptide with adequately high specific activity, so that required therapeutic efficacy can be achieved without saturating the limited number of receptors available on the target lesions. Specific activity of the radionuclide and the radiolabeled somatostatin analog are therefore an important parameters. Although these analogs have been investigated and improved, and successfully applied for PRRT for more than 15 years, there are still many possibilities for further improvements that fully exploit PRRT with 177Lu-DOTA-TATE. The here summarized data presented herein on increased knowledge of the components of 177Lu-DOTA-TATE (especially the purity of 177Lu and specific activity of 177Lu) and the reaction kinetics during labeling 177Lu-DOTA-TATE clearly show that the peptide dose and dose in GBq can be varied. Here we present an overview of the development, formulation and optimisation of 177Lu-DOTA-TATE, mainly addressing radiochemical parameters.

An overview on development and application of an experimental platform for quantitative cardiac imaging research in rabbit models of myocardial infarction

PubMed Central

Feng, Yuanbo; Bogaert, Jan; Oyen, Raymond

2014-01-01

To exploit the advantages of using rabbits for cardiac imaging research and to tackle the technical obstacles, efforts have been made under the framework of a doctoral research program. In this overview article, by cross-referencing the current literature, we summarize how we have developed a preclinical cardiac research platform based on modified models of reperfused myocardial infarction (MI) in rabbits; how the in vivo manifestations of cardiac imaging could be closely matched with those ex vivo macro- and microscopic findings; how these imaging outcomes could be quantitatively analyzed, validated and demonstrated; and how we could apply this cardiac imaging platform to provide possible solutions to certain lingering diagnostic and therapeutic problems in experimental cardiology. In particular, tissue components in acute cardiac ischemia have been stratified and characterized, post-infarct lipomatous metaplasia (LM) as a common but hardly illuminated clinical pathology has been identified in rabbit models, and a necrosis avid tracer as well as an anti-ischemic drug have been successfully assessed for their potential utilities in clinical cardiology. These outcomes may interest the researchers in the related fields and help strengthen translational research in cardiovascular diseases. PMID:25392822

An overview on development and application of an experimental platform for quantitative cardiac imaging research in rabbit models of myocardial infarction.

PubMed

Feng, Yuanbo; Bogaert, Jan; Oyen, Raymond; Ni, Yicheng

2014-10-01

To exploit the advantages of using rabbits for cardiac imaging research and to tackle the technical obstacles, efforts have been made under the framework of a doctoral research program. In this overview article, by cross-referencing the current literature, we summarize how we have developed a preclinical cardiac research platform based on modified models of reperfused myocardial infarction (MI) in rabbits; how the in vivo manifestations of cardiac imaging could be closely matched with those ex vivo macro- and microscopic findings; how these imaging outcomes could be quantitatively analyzed, validated and demonstrated; and how we could apply this cardiac imaging platform to provide possible solutions to certain lingering diagnostic and therapeutic problems in experimental cardiology. In particular, tissue components in acute cardiac ischemia have been stratified and characterized, post-infarct lipomatous metaplasia (LM) as a common but hardly illuminated clinical pathology has been identified in rabbit models, and a necrosis avid tracer as well as an anti-ischemic drug have been successfully assessed for their potential utilities in clinical cardiology. These outcomes may interest the researchers in the related fields and help strengthen translational research in cardiovascular diseases.

CoSEC: Connecting Living With a Star Research

NASA Astrophysics Data System (ADS)

Hurlburt, N.; Freeland, S.; Bose, P.; Zimdars, A.; Slater, G.

2006-12-01

The Collaborative Sun-Earth Connector (CoSEC) provide the means for heliophysics researchers to compose the data sources and processing services published by their peers into processing workflows that reliably generate publication-worthy data. It includes: composition of computational and data services into easy-to- read workflows with data quality and version traceability; straightforward translation of existing services into workflow components, and advertisement of those components to other members of the CoSEC community; annotation of published services with functional attributes to enable discovery of capabilities required by particular workflows and identify peer subgroups in the CoSEC community; and annotation of published services with nonfunctional attributes to enable selection on the basis of quality of service (QoS). We present an overview and demonstration of the CoSEC system, discuss applications, the lessons learned and future developments.

Laboratory models for central nervous system tumor stem cell research.

PubMed

Khan, Imad Saeed; Ehtesham, Moneeb

2015-01-01

Central nervous system (CNS) tumors are complex organ systems comprising of a neoplastic component with associated vasculature, inflammatory cells, and reactive cellular and extracellular components. Research has identified a subset of cells in CNS tumors that portray defining properties of neural stem cells, namely, that of self-renewal and multi-potency. Growing evidence suggests that these tumor stem cells (TSC) play an important role in the maintenance and growth of the tumor. Furthermore, these cells have also been shown to be refractory to conventional therapy and may be crucial for tumor recurrence and metastasis. Current investigations are focusing on isolating these TSC from CNS tumors to investigate their unique biological processes. This understanding will help identify and develop more effective and comprehensive treatment strategies. This chapter provides an overview of some of the most commonly used laboratory models for CNSTSC research.

Overview of ARPA low-cost ceramic composites (LC{sup 3}) program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adler, P.N.

1996-12-31

Grumman is currently leading an approximate $10M ARPA cost-shared program aimed at developing low-cost fabrication methodology for manufacturing ceramic matrix composite (CMC) structural components. One of the program goals is to demonstrate the effectiveness of an advanced materials partnership. A vertically integrated collaboration now exists that combines the talents of three large private sector organizations, two smaller private sector organizations, three universities, and three federal government laboratories. Work in progress involves preceramic polymer (Blackglas{trademark}) CMC materials technology, RTM and pyrolysis process modeling & simulation, and utilization of low-cost approaches for fabricating a CMC demonstration engine seal component. This paper reviewsmore » the program organization, functioning, and some of the highlights of the technical work, which is of interest to the DoD as well as the commercial sector.« less

Engineered Graphene Materials: Synthesis and Applications for Polymer Electrolyte Membrane Fuel Cells.

PubMed

He, Daping; Tang, Haolin; Kou, Zongkui; Pan, Mu; Sun, Xueliang; Zhang, Jiujun; Mu, Shichun

2017-05-01

Engineered graphene materials (EGMs) with unique structures and properties have been incorporated into various components of polymer electrolyte membrane fuel cells (PEMFCs) such as electrode, membrane, and bipolar plates to achieve enhanced performances in terms of electrical conductivity, mechanical durability, corrosion resistance, and electrochemical surface area. This research news article provides an overview of the recent development in EGMs and EGM-based PEMFCs with a focus on the effects of EGMs on PEMFC performance when they are incorporated into different components of PEMFCs. The challenges of EGMs for practical PEMFC applications in terms of production scale, stability, conductivity, and coupling capability with other materials are also discussed and the corresponding measures and future research trends to overcome such challenges are proposed. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Continuity and Integration in Early Childhood Education: PDC

ERIC Educational Resources Information Center

Braggett, E. J.

1977-01-01

Gives an overview of the United States' Project Developmental Continuity. Discussed are administration, education, preservice and inservice training, developmental support services, parent involvement, handicapped, and bilingual/bicultural components. (SB)

Formative research methods for designing culturally appropriate, integrated child nutrition and development interventions: An overview

PubMed Central

Bentley, Margaret E.; Johnson, Susan L.; Wasser, Heather; Creed-Kanashiro, Hilary; Shroff, Monal; Fernandez-Rao, Sylvia; Cunningham, Melissa

2014-01-01

Nutritional and developmental insults in the first few years of life have profound public health implications, including substantial contributions to neonatal, infant, and early childhood morbidity and mortality, as well as longer term impacts on cognitive development, school achievement, and worker productivity. Optimal development that can lead to the attainment of the individual's fullest potential therefore requires a combination of genetic capacity, adequate nutrition, psychosocial stimulation, and safe, clean physical environments. Researchers and policymakers have called for integrated child nutrition and development interventions for more than twenty years, yet there are only a handful of efficacy trials and even fewer examples of integrated interventions that have been taken to scale. While a critical component to the design of such interventions is formative research, there is a dearth of information in both the literature and policy arenas to guide this phase of the process. To move the field forward, this paper first provides an overview of formative research methods with a focus on qualitative inquiry, a description of the critical domains to be assessed (infant and young child feeding, responsive feeding, and child development), and currently available resources. Application of these methods is provided through a real-world case study—the design of an integrated nutrition and child development efficacy trial in Andhra Pradesh, India. Recommendations for next steps are discussed, the most important of which is the need for a comprehensive set of formative guidelines for designing locally tailored, culturally appropriate integrated interventions. PMID:24673167

The overview effect: the impact of space exploration on the evolution of nursing science.

PubMed

Butcher, H K; Forchuk, C

1992-01-01

The purpose of this article is to explore the overview effect, an experience evoked by space travel that has the capacity to transform all patterns of human existence and evolution toward greater potentials in human diversity and creativity. As nurses migrate with humanity into the solar system and beyond, they will experience the overview effect. The core components of the effect include changed perceptions of space, time, sound, and weight which have the potential to transform the evolution of nursing science. Nursing paradigms will encompass a view of humanity as integral with an infinite evolutionary universe. After generations of living in space in a diversity of new environments, the physical body will undergo radical changes, and the meaning of health will be transformed. The article concludes with a discussion on the parallels between Rogers' science of unitary human beings and the overview effect.

Earth resources instrumentation for the Space Station Polar Platform

NASA Technical Reports Server (NTRS)

Donohoe, Martin J.; Vane, Deborah

1986-01-01

The spacecraft and payloads of the Space Station Polar Platform program are described in a brief overview. Present plans call for one platform in a descending morning-equator-crossing orbit at 824 km and two or three platforms in ascending afternoon-crossing orbits at 542-824 km. The components of the NASA Earth Observing System (EOS) and NOAA payloads are listed in tables and briefly characterized, and data-distribution requirements and the mission development schedule are discussed. A drawing of the platform, a graph showing the spectral coverage of the EOS instruments, and a glossary of acronyms are provided.

Bioinformatics of prokaryotic RNAs

PubMed Central

Backofen, Rolf; Amman, Fabian; Costa, Fabrizio; Findeiß, Sven; Richter, Andreas S; Stadler, Peter F

2014-01-01

The genome of most prokaryotes gives rise to surprisingly complex transcriptomes, comprising not only protein-coding mRNAs, often organized as operons, but also harbors dozens or even hundreds of highly structured small regulatory RNAs and unexpectedly large levels of anti-sense transcripts. Comprehensive surveys of prokaryotic transcriptomes and the need to characterize also their non-coding components is heavily dependent on computational methods and workflows, many of which have been developed or at least adapted specifically for the use with bacterial and archaeal data. This review provides an overview on the state-of-the-art of RNA bioinformatics focusing on applications to prokaryotes. PMID:24755880

Diamond like carbon nanocomposites with embedded metallic nanoparticles

NASA Astrophysics Data System (ADS)

Tamulevičius, Sigitas; Meškinis, Šarūnas; Tamulevičius, Tomas; Rubahn, Horst-Günter

2018-02-01

In this work we present an overview on structure formation, optical and electrical properties of diamond like carbon (DLC) based metal nanocomposites deposited by reactive magnetron sputtering and treated by plasma and laser ablation methods. The influence of deposition mode and other technological conditions on the properties of the nanosized filler, matrix components and composition were studied systematically in relation to the final properties of the nanocomposites. Applications of the nanocomposites in the development of novel biosensors combining resonance response of wave guiding structures in DLC based nanocomposites as well as plasmonic effects are also presented.

The development of imitation in infancy

PubMed Central

Jones, Susan S.

2009-01-01

An overview of existing data on imitation in infancy suggests that changes in the direction of imitation research are underway. The widely accepted view that newborn infants imitate lacks supporting evidence. Instead, existing data suggest that infants do not imitate others until their second year, and that imitation of different kinds of behaviour emerges at different ages. The evidence is consistent with a dynamic systems account in which the ability to imitate is not an inherited, specialized module, but is instead the emergent product of a system of social, cognitive and motor components, each with its own developmental history. PMID:19620104

Status and Assessment of Chesapeake Bay Wildlife Contamination

USGS Publications Warehouse

Heinz, G.H.; Wiemeyer, Stanley N.; Clark, D.R.; Albers, P.H.; Henry, P.; Batiuk, R.A.

1992-01-01

As an integral component of its priority setting process, the Chesapeake Bay Program`s Toxics Subcommittee has sought the expertise of Chesapeake Bay researchers and managers in developing a series of Chesapeake Bay toxics status and assessment papers. In the report, evidence for historical and current contaminant effects on key bird species, mammals, reptiles and amphibians which inhabit the Chesapeake Bay basin is examined. For each group of wildlife species, a general overview of effects caused by specific toxic substances is followed by detailed accounts of contaminant effects on selected species. Sponsored by Environmental Protection Agency, Annapolis, MD. Chesapeake Bay Program.

Using real-time fMRI brain-computer interfacing to treat eating disorders.

PubMed

Sokunbi, Moses O

2018-05-15

Real-time functional magnetic resonance imaging based brain-computer interfacing (fMRI neurofeedback) has shown encouraging outcomes in the treatment of psychiatric and behavioural disorders. However, its use in the treatment of eating disorders is very limited. Here, we give a brief overview of how to design and implement fMRI neurofeedback intervention for the treatment of eating disorders, considering the basic and essential components. We also attempt to develop potential adaptations of fMRI neurofeedback intervention for the treatment of anorexia nervosa, bulimia nervosa and binge eating disorder. Copyright © 2018 Elsevier B.V. All rights reserved.

Historical flight qualifications of space nuclear systems

NASA Astrophysics Data System (ADS)

Bennett, Gary L.

1997-01-01

An overview is presented of the qualification programs for the general-purpose heat source radioisotope thermoelectric generators (GPHS-RTGs) as developed for the Galileo and Ulysses missions; the SNAP-10A space reactor; the Nuclear Engine for Rocket Vehicle Applications (NERVA); the F-1 chemical rocket engine used on the Saturn-V Apollo lunar missions; and the Space Shuttle Main Engines (SSMEs). Some similarities and contrasts between the qualification testing employed on these five programs will be noted. One common thread was that in each of these successful programs there was an early focus on component and subsystem tests to uncover and correct problems.

Modeling hydraulic regenerative hybrid vehicles using AMESim and Matlab/Simulink

NASA Astrophysics Data System (ADS)

Lynn, Alfred; Smid, Edzko; Eshraghi, Moji; Caldwell, Niall; Woody, Dan

2005-05-01

This paper presents the overview of the simulation modeling of a hydraulic system with regenerative braking used to improve vehicle emissions and fuel economy. Two simulation software packages were used together to enhance the simulation capability for fuel economy results and development of vehicle and hybrid control strategy. AMESim, a hydraulic simulation software package modeled the complex hydraulic circuit and component hardware and was interlinked with a Matlab/Simulink model of the vehicle, engine and the control strategy required to operate the vehicle and the hydraulic hybrid system through various North American and European drive cycles.

Next-generation materials for future synchrotron and free-electron laser sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Assoufid, Lahsen; Graafsma, Heinz

We show that the development of new materials and improvements of existing ones are at the root of the spectacular recent developments of new technologies for synchrotron storage rings and free-electron laser sources. This holds true for all relevant application areas, from electron guns to undulators, x-ray optics, and detectors. As demand grows for more powerful and efficient light sources, efficient optics, and high-speed detectors, an overview of ongoing materials research for these applications is timely. In this article, we focus on the most exciting and demanding areas of materials research and development for synchrotron radiation optics and detectors. Materialsmore » issues of components for synchrotron and free-electron laser accelerators are briefly discussed. Lastly, the articles in this issue expand on these topics.« less

Next-generation materials for future synchrotron and free-electron laser sources

DOE PAGES

Assoufid, Lahsen; Graafsma, Heinz

2017-06-09

We show that the development of new materials and improvements of existing ones are at the root of the spectacular recent developments of new technologies for synchrotron storage rings and free-electron laser sources. This holds true for all relevant application areas, from electron guns to undulators, x-ray optics, and detectors. As demand grows for more powerful and efficient light sources, efficient optics, and high-speed detectors, an overview of ongoing materials research for these applications is timely. In this article, we focus on the most exciting and demanding areas of materials research and development for synchrotron radiation optics and detectors. Materialsmore » issues of components for synchrotron and free-electron laser accelerators are briefly discussed. Lastly, the articles in this issue expand on these topics.« less

Field Plan and Implementation Package for the Ethnographic Component of the Child and Family Mental Health Project Evaluation.

ERIC Educational Resources Information Center

Macias, Jose; And Others

This report contains the field plan and implementation procedures which were utilized for the observational/focused ethnographic component of Head Start's Child and Family Mental Health (CFMH) Evaluation Project. The introductory section of the document provides the reader with an overview of the Head Start program, its mental health goals, the…

Netscape Communicator 4.5. Volume I: The Basic Functions of the Navigator Component.

ERIC Educational Resources Information Center

Gallo, Gail; Wichowski, Chester P.

This first of two guides on Netscape Communicator 4.5 contains six lessons on the basic functions of the Navigator component. Lesson 1 covers terminology and methods to connect to the World Wide Web, hardware needed, and a Netscape Communicator overview. Lesson 2 introduces the Navigator window, toolbars, and menus, and how to change the default…

Overview of the recent DiMES and MiMES experiments in DIII-D

NASA Astrophysics Data System (ADS)

Rudakov, D. L.; Wong, C. P. C.; Litnovsky, A.; Wampler, W. R.; Boedo, J. A.; Brooks, N. H.; Fenstermacher, M. E.; Groth, M.; Hollmann, E. M.; Jacob, W.; Krasheninnikov, S. I.; Krieger, K.; Lasnier, C. J.; Leonard, A. W.; McLean, A. G.; Marot, M.; Moyer, R. A.; Petrie, T. W.; Philipps, V.; Smirnov, R. D.; Stangeby, P. C.; Watkins, J. G.; West, W. P.; Yu, J. H.

2009-12-01

Divertor and midplane material evaluation systems (DiMES and MiMES) in the DIII-D tokamak are used to address a variety of plasma-material interaction (PMI) issues relevant to ITER. Among the topics studied are carbon erosion and re-deposition, hydrogenic retention in the gaps between plasma-facing components (PFCs), deterioration of diagnostic mirrors from carbon deposition and techniques to mitigate that deposition, and dynamics and transport of dust. An overview of the recent experimental results is presented.

The planned Alaska SAR Facility - An overview

NASA Technical Reports Server (NTRS)

Carsey, Frank; Weeks, Wilford

1987-01-01

The Alaska SAR Facility (ASF) is described in an overview fashion. The facility consists of three major components, a Receiving Ground System, a SAR Processing System and an Analysis and Archiving System; the ASF Program also has a Science Working Team and the requisite management and operations systems. The ASF is now an approved and fully funded activity; detailed requirements and science background are presented for the facility to be implemented for data from the European ERS-1, the Japanese ERS-1 and Radarsat.

WEAVE an overview and status update

NASA Astrophysics Data System (ADS)

Bonifacio, P.; Dalton, G.; Trager, S.; Aguerri, A. L.; Carrasco, E.; Vallenari, A.; Abrams, D. C.; Middleton, K.; Sayède, F.

2016-12-01

The WHT Enhanced Area Velocity Explorer is a high multiplex, multi-object spectrograph that will equip the prime focus of the WHT 4.2m telescope. The instrument is currently in the construction phase and several components have already been procured. I will give a short overview of the instrument and of the project and its status. The French participation is done through CNRS - Institut National des Sciences de l'Univers and the technical activity is carried out, at this stage, at GEPI, Observatoire de Paris.

An overview of the model integration process: From pre ...

EPA Pesticide Factsheets

Integration of models requires linking models which can be developed using different tools, methodologies, and assumptions. We performed a literature review with the aim of improving our understanding of model integration process, and also presenting better strategies for building integrated modeling systems. We identified five different phases to characterize integration process: pre-integration assessment, preparation of models for integration, orchestration of models during simulation, data interoperability, and testing. Commonly, there is little reuse of existing frameworks beyond the development teams and not much sharing of science components across frameworks. We believe this must change to enable researchers and assessors to form complex workflows that leverage the current environmental science available. In this paper, we characterize the model integration process and compare integration practices of different groups. We highlight key strategies, features, standards, and practices that can be employed by developers to increase reuse and interoperability of science software components and systems. The paper provides a review of the literature regarding techniques and methods employed by various modeling system developers to facilitate science software interoperability. The intent of the paper is to illustrate the wide variation in methods and the limiting effect the variation has on inter-framework reuse and interoperability. A series of recommendation

Development of a direct education workshop for cervical cancer prevention in high risk women: the Forsyth County project.

PubMed

Dignan, M B; Beal, P E; Michielutte, R; Sharp, P C; Daniels, L A; Young, L D

1990-01-01

With funding from the National Cancer Institute, a public health education program was developed with the primary objective of increasing the proportion of black women in Forsyth County, North Carolina, who receive Pap smears on a regular basis. This paper reports on the development and implementation of the direct education component of the program. The content of the workshop was based on community analysis of current knowledge, attitudes, and behaviors in the target population, and a review of relevant literature on cervical cancer and the Pap smear. Methods for presentation of the content were refined through three pilot tests. Audiovisual materials were also developed to illustrate key points. The direct education component of the program was designed to function as a short workshop and includes an overview of healthy lifestyles, coverage of the importance of early detection of cancer, a description and discussion of the pelvic exam and the Pap smear, and a discussion of common barriers to obtaining Pap smears on a regular basis. Evaluation of the workshop emphasizes process measures, including a questionnaire to collect demographic information and impressions of the presentation. Interim results of the evaluation are discussed.

Retrieval of overviews of systematic reviews in MEDLINE was improved by the development of an objectively derived and validated search strategy.

PubMed

Lunny, Carole; McKenzie, Joanne E; McDonald, Steve

2016-06-01

Locating overviews of systematic reviews is difficult because of an absence of appropriate indexing terms and inconsistent terminology used to describe overviews. Our objective was to develop a validated search strategy to retrieve overviews in MEDLINE. We derived a test set of overviews from the references of two method articles on overviews. Two population sets were used to identify discriminating terms, that is, terms that appear frequently in the test set but infrequently in two population sets of references found in MEDLINE. We used text mining to conduct a frequency analysis of terms appearing in the titles and abstracts. Candidate terms were combined and tested in MEDLINE in various permutations, and the performance of strategies measured using sensitivity and precision. Two search strategies were developed: a sensitivity-maximizing strategy, achieving 93% sensitivity (95% confidence interval [CI]: 87, 96) and 7% precision (95% CI: 6, 8), and a sensitivity-and-precision-maximizing strategy, achieving 66% sensitivity (95% CI: 58, 74) and 21% precision (95% CI: 17, 25). The developed search strategies enable users to more efficiently identify overviews of reviews compared to current strategies. Consistent language in describing overviews would aid in their identification, as would a specific MEDLINE Publication Type. Copyright © 2015 Elsevier Inc. All rights reserved.

Three-component laser anemometer measurement systems

NASA Technical Reports Server (NTRS)

Goldman, Louis J.

1991-01-01

A brief overview of the different laser anemometer (LA) optical designs available is presented. Then, the LA techniques that can be used to design a three-component measurement system for annular geometries are described. Some of the facility design considerations unique to these LA systems are also addressed. Following this, the facilities and the LA systems that were used to successfully measure the three components of velocity in the blading of annular-flow machines are reviewed. Finally, possible LA system enhancements and future research directions are presented.

Antioxidant activity of food constituents: an overview.

PubMed

Gülçin, İlhami

2012-03-01

Recently, there has been growing interest in research into the role of plant-derived antioxidants in food and human health. The beneficial influence of many foodstuffs and beverages including fruits, vegetables, tea, coffee, and cacao on human health has been recently recognized to originate from their antioxidant activity. For this purpose, the most commonly methods used in vitro determination of antioxidant capacity of food constituents are reviewed and presented. Also, the general chemistry underlying the assays in the present paper was clarified. Hence, this overview provides a basis and rationale for developing standardized antioxidant capacity methods for the food, nutraceutical, and dietary supplement industries. In addition, the most important advantages and shortcomings of each method were detected and highlighted. The chemical principles of these methods are outlined and critically discussed. The chemical principles of methods of 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulphonate) radical (ABTS(·+)) scavenging, 1,1-diphenyl-2-picrylhydrazyl (DPPH(·)) radical scavenging, Fe(3+)-Fe(2+) transformation assay, ferric reducing antioxidant power (FRAP) assay, cupric ions (Cu(2+)) reducing power assay (Cuprac), Folin-Ciocalteu reducing capacity (FCR assay), peroxyl radical scavenging, superoxide anion radical (O (2) (·-)) scavenging, hydrogen peroxide (H(2)O(2)) scavenging, hydroxyl radical (OH(·)) scavenging, singlet oxygen ((1)O(2)) quenching assay and nitric oxide radical (NO(·)) scavenging assay are outlined and critically discussed. Also, the general antioxidant aspects of main food components were discussed by a number of methods which are currently used for detection of antioxidant properties food components. This review consists of two main sections. The first section is devoted to main components in the foodstuffs and beverages. The second general section is some definitions of the main antioxidant methods commonly used for determination of antioxidant activity of components in the foodstuffs and beverages. In addition, there are given some chemical and kinetic basis and technical details of the used methods.

CALS Infrastructure Analysis. Draft. Volume 21

DOT National Transportation Integrated Search

1990-03-01

This executive overview to the DoD CALS Infrastructure Analysis Report summarizes the Components' current effort to modernize the DoD technical data infrastructure. This infrastructure includes all existing and planned capabilities to acquire, manage...

A statewide strategy for nursing workforce development through partnerships in Texas.

PubMed

Kishi, Aileen; Green, Alexia

2008-08-01

Statewide efforts and partnerships were used for nursing workforce development to address the nursing shortage in Texas. A statewide strategic action plan was developed where partnerships and collaboration were the key components. One of the most important outcomes of these statewide partnerships was the passage of the Nursing Shortage Reduction Act 2001. Through this legislation, the Texas Center for Nursing Workforce Studies and its advisory committee were established. This article describes how a statewide infrastructure for nursing workforce policy and legislative and regulatory processes were further developed. An overview is provided on the contributions made by the organizations involved with these strategic partnerships. The ingredients for establishing successful, strategic partnerships are also identified. It is hoped that nursing and health care leaders striving to address the nursing shortage could consider statewide efforts such as those used in Texas to develop nursing workforce policy and legislation.

Review on Rapid Seismic Vulnerability Assessment for Bulk of Buildings

NASA Astrophysics Data System (ADS)

Nanda, R. P.; Majhi, D. R.

2013-09-01

This paper provides a brief overview of rapid visual screening (RVS) procedures available in different countries with a comparison among all the methods. Seismic evaluation guidelines from, USA, Canada, Japan, New Zealand, India, Europe, Italy, UNDP, with other methods are reviewed from the perspective of their applicability to developing countries. The review shows clearly that some of the RVS procedures are unsuited for potential use in developing countries. It is expected that this comparative assessment of various evaluation schemes will help to identify the most essential components of such a procedure for use in India and other developing countries, which is not only robust, reliable but also easy to use with available resources. It appears that Federal Emergency Management Agency (FEMA) 154 and New Zealand Draft Code approaches can be suitably combined to develop a transparent, reasonably rigorous and generalized procedure for seismic evaluation of buildings in developing countries.

Digital Therapeutics: An Integral Component of Digital Innovation in Drug Development.

PubMed

Sverdlov, Oleksandr; van Dam, Joris; Hannesdottir, Kristin; Thornton-Wells, Tricia

2018-07-01

Digital therapeutics represent a new treatment modality in which digital systems such as smartphone apps are used as regulatory-approved, prescribed therapeutic interventions to treat medical conditions. In this article we provide a critical overview of the rationale for investing in such novel modalities, including the unmet medical needs addressed by digital therapeutics and the potential for reducing current costs of medical care. We also discuss emerging pathways to regulatory approval and how innovative business models are enabling further growth in the development of digital therapeutics. We conclude by providing some recent examples of digital therapeutics that have gained regulatory approval and highlight opportunities for the near future. © 2018 American Society for Clinical Pharmacology and Therapeutics.

Computer validation in toxicology: historical review for FDA and EPA good laboratory practice.

PubMed

Brodish, D L

1998-01-01

The application of computer validation principles to Good Laboratory Practice is a fairly recent phenomenon. As automated data collection systems have become more common in toxicology facilities, the U.S. Food and Drug Administration and the U.S. Environmental Protection Agency have begun to focus inspections in this area. This historical review documents the development of regulatory guidance on computer validation in toxicology over the past several decades. An overview of the components of a computer life cycle is presented, including the development of systems descriptions, validation plans, validation testing, system maintenance, SOPs, change control, security considerations, and system retirement. Examples are provided for implementation of computer validation principles on laboratory computer systems in a toxicology facility.

An overview of the space medicine program and development of the Health Maintenance Facility for Space Station

NASA Technical Reports Server (NTRS)

Pool, Sam Lee

1988-01-01

Because the prolonged stay on board the Space Station will increase the risk of possible inflight medical problems from that on Skylab missions, the Health Maintenance Facility (HMF) planned for the Space Station is much more sophisticated than the small clinics of the Skylab missions. The development of the HMF is directed by the consideration of three primary factors: prevention, diagnosis, and treatment of injuries and illnesses that may occur in flight. The major components of the HMF include the clinical laboratory, pharmacy, imaging system, critical-care system, patient-restraint system, data-management system, exercise system, surgical system, electrophysiologic-monitoring system, introvenous-fluid system, dental system, and hyperbaric-treatment-support system.

Mood dysregulation and stabilization: perspectives from emotional cognitive neuroscience.

PubMed

Yamawaki, Shigeto; Okada, Go; Okamoto, Yasumasa; Liberzon, Israel

2012-06-01

Mood is conceptualized as a long-lasting emotional state, which can have profound implications for mental and physical health. The development of neuroimaging methods has enabled significant advances towards elucidating the mechanisms underlying regulation of mood and emotion; however, our understanding of mood and emotion dysregulation in stress-related psychiatric disorders is still largely lacking. From the cognitive-affective neuroscience perspective, achieving deeper, more mechanistic understanding of mood disorders necessitates detailed understanding of specific components of neural systems involved in mood dysregulation and stabilization. In this review, we provide an overview of neural systems implicated in the development of a long-term negative mood state, as well as those related to emotion and emotion regulation, and discuss their proposed involvement in mood and anxiety disorders.

CellML metadata standards, associated tools and repositories

PubMed Central

Beard, Daniel A.; Britten, Randall; Cooling, Mike T.; Garny, Alan; Halstead, Matt D.B.; Hunter, Peter J.; Lawson, James; Lloyd, Catherine M.; Marsh, Justin; Miller, Andrew; Nickerson, David P.; Nielsen, Poul M.F.; Nomura, Taishin; Subramanium, Shankar; Wimalaratne, Sarala M.; Yu, Tommy

2009-01-01

The development of standards for encoding mathematical models is an important component of model building and model sharing among scientists interested in understanding multi-scale physiological processes. CellML provides such a standard, particularly for models based on biophysical mechanisms, and a substantial number of models are now available in the CellML Model Repository. However, there is an urgent need to extend the current CellML metadata standard to provide biological and biophysical annotation of the models in order to facilitate model sharing, automated model reduction and connection to biological databases. This paper gives a broad overview of a number of new developments on CellML metadata and provides links to further methodological details available from the CellML website. PMID:19380315

Overview of Radiation Environments and Human Exposures

NASA Technical Reports Server (NTRS)

Wilson, John W.

2004-01-01

Human exposures to ionizing radiation have been vastly altered by developing technology in the last century. This has been most obvious in the development of radiation generating devices and the utilization of nuclear energy. But even air travel has had its impact on human exposure. Human exposure increases with advancing aircraft technology as a result of the higher operating altitudes reducing the protective cover provided by the Earth s atmosphere from extraterrestrial radiations. This increase in operating altitudes is taken to a limit by human operations in space. Less obvious is the changing character of the radiations at higher altitudes. The associated health risks are less understood with increasing altitude due to the increasing complexity and new field components found in high altitude and space operations.

Demonstration of a magnetic refrigerator for high temperature superconducting electric power applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murphy, R.W.; Zimm, C.B.

1994-07-29

This presentation/paper gives an overview of the Oak Ridge National Lab`s collaboration with private industry in developing electric power applications for magnetic refrigeraters which use high temperature superconductors. Highlighted is the lab`s general approach and technical progress towards advancing magnetic refrigeration technology in the 20-80 K range by specifically developing a prototype magnetic cryocooler with could provide 50 W cooling at 40 K. Included is magnet schematics; a listing of the basic components; load points; magnet charge and cooldown; vendor for induction alloying elements; and performance testing. The projects are in collaboration with Astronautics Corporation of America and included aremore » the proposed projects for FY 1995, key personnel, and the fiscal 1994 budgets.« less

CURRENT CONCEPTS OF PLYOMETRIC EXERCISE.

PubMed

Davies, George; Riemann, Bryan L; Manske, Robert

2015-11-01

As knowledge regarding rehabilitation science continues to increase, exercise programs following musculoskeletal athletic injury continue to evolve. Rehabilitation programs have drastically changed, especially in the terminal phases of rehabilitation, which include performance enhancement, development of power, and a safe return to activity. Plyometric exercise has become an integral component of late phase rehabilitation as the patient nears return to activity. Among the numerous types of available exercises, plyometrics assist in the development of power, a foundation from which the athlete can refine the skills of their sport. Therefore, the purpose of this clinical commentary is to provide an overview of plyometrics including: definition, phases, the physiological, mechanical and neurophysiological basis of plyometrics, and to describe clinical guidelines and contraindications for implementing plyometric programs.

Technology initiatives for the autonomous guidance, navigation, and control of single and multiple satellites

NASA Astrophysics Data System (ADS)

Croft, John; Deily, John; Hartman, Kathy; Weidow, David

1998-01-01

In the twenty-first century, NASA envisions frequent low-cost missions to explore the solar system, observe the universe, and study our planet. To realize NASA's goal, the Guidance, Navigation, and Control Center (GNCC) at the Goddard Space Flight Center sponsors technology programs that enhance spacecraft performance, streamline processes and ultimately enable cheaper science. Our technology programs encompass control system architectures, sensor and actuator components, electronic systems, design and development of algorithms, embedded systems and space vehicle autonomy. Through collaboration with government, universities, non-profit organizations, and industry, the GNCC incrementally develops key technologies that conquer NASA's challenges. This paper presents an overview of several innovative technology initiatives for the autonomous guidance, navigation, and control (GN&C) of satellites.

Wastewater Collection.

ERIC Educational Resources Information Center

Chatterjee, Samar; And Others

1978-01-01

Presents a literature review of wastewater collection systems and components. This review covers: (1) planning, (2) construction; (3) sewer system evaluation; (4) maintenance; (5) rehabilitation; (6) overview prevention; and (7) wastewater pumping. A list of 111 references is also presented. (HM)

Laser-GMA Hybrid Pipe Welding System

DTIC Science & Technology

2007-11-01

Experimental Results.................................................................................................34 Autogenous Laser Welds...APPENDIX B. Training Manual – Overview of System Components and Software...................... APPENDIX C. NASSCO...17. Autogenous laser welds in different joint configurations (10 mm thick mild steel, 5 mm land

Construction and Characterization of External Cavity Diode Lasers for Atomic Physics

PubMed Central

Hardman, Kyle S.; Bennetts, Shayne; Debs, John E.; Kuhn, Carlos C. N.; McDonald, Gordon D.; Robins, Nick

2014-01-01

Since their development in the late 1980s, cheap, reliable external cavity diode lasers (ECDLs) have replaced complex and expensive traditional dye and Titanium Sapphire lasers as the workhorse laser of atomic physics labs1,2. Their versatility and prolific use throughout atomic physics in applications such as absorption spectroscopy and laser cooling1,2 makes it imperative for incoming students to gain a firm practical understanding of these lasers. This publication builds upon the seminal work by Wieman3, updating components, and providing a video tutorial. The setup, frequency locking and performance characterization of an ECDL will be described. Discussion of component selection and proper mounting of both diodes and gratings, the factors affecting mode selection within the cavity, proper alignment for optimal external feedback, optics setup for coarse and fine frequency sensitive measurements, a brief overview of laser locking techniques, and laser linewidth measurements are included. PMID:24796259

ATM Technology Demonstration-1 Phase II Boeing Configurable Graphical Display (CGD) Software Design Description

NASA Technical Reports Server (NTRS)

Wilber, George F.

2017-01-01

This Software Description Document (SDD) captures the design for developing the Flight Interval Management (FIM) system Configurable Graphics Display (CGD) software. Specifically this SDD describes aspects of the Boeing CGD software and the surrounding context and interfaces. It does not describe the Honeywell components of the CGD system. The SDD provides the system overview, architectural design, and detailed design with all the necessary information to implement the Boeing components of the CGD software and integrate them into the CGD subsystem within the larger FIM system. Overall system and CGD system-level requirements are derived from the CGD SRS (in turn derived from the Boeing System Requirements Design Document (SRDD)). Display and look-and-feel requirements are derived from Human Machine Interface (HMI) design documents and working group recommendations. This Boeing CGD SDD is required to support the upcoming Critical Design Review (CDR).

The Iterative Research Cycle: Process-Based Model Evaluation

NASA Astrophysics Data System (ADS)

Vrugt, J. A.

2014-12-01

The ever increasing pace of computational power, along with continued advances in measurement technologies and improvements in process understanding has stimulated the development of increasingly complex physics based models that simulate a myriad of processes at different spatial and temporal scales. Reconciling these high-order system models with perpetually larger volumes of field data is becoming more and more difficult, particularly because classical likelihood-based fitting methods lack the power to detect and pinpoint deficiencies in the model structure. In this talk I will give an overview of our latest research on process-based model calibration and evaluation. This approach, rooted in Bayesian theory, uses summary metrics of the calibration data rather than the data itself to help detect which component(s) of the model is (are) malfunctioning and in need of improvement. A few case studies involving hydrologic and geophysical models will be used to demonstrate the proposed methodology.

Overview of Engineering Design and Analysis at the NASA John C. Stennis Space Center

NASA Technical Reports Server (NTRS)

Ryan, Harry; Congiardo, Jared; Junell, Justin; Kirkpatrick, Richard

2007-01-01

A wide range of rocket propulsion test work occurs at the NASA John C. Stennis Space Center (SSC) including full-scale engine test activities at test facilities A-1, A-2, B-1 and B-2 as well as combustion device research and development activities at the E-Complex (E-1, E-2, E-3 and E-4) test facilities. The propulsion test engineer at NASA SSC faces many challenges associated with designing and operating a test facility due to the extreme operating conditions (e.g., cryogenic temperatures, high pressures) of the various system components and the uniqueness of many of the components and systems. The purpose of this paper is to briefly describe the NASA SSC Engineering Science Directorate s design and analysis processes, experience, and modeling techniques that are used to design and support the operation of unique rocket propulsion test facilities.

Construction and characterization of external cavity diode lasers for atomic physics.

PubMed

Hardman, Kyle S; Bennetts, Shayne; Debs, John E; Kuhn, Carlos C N; McDonald, Gordon D; Robins, Nick

2014-04-24

Since their development in the late 1980s, cheap, reliable external cavity diode lasers (ECDLs) have replaced complex and expensive traditional dye and Titanium Sapphire lasers as the workhorse laser of atomic physics labs. Their versatility and prolific use throughout atomic physics in applications such as absorption spectroscopy and laser cooling makes it imperative for incoming students to gain a firm practical understanding of these lasers. This publication builds upon the seminal work by Wieman, updating components, and providing a video tutorial. The setup, frequency locking and performance characterization of an ECDL will be described. Discussion of component selection and proper mounting of both diodes and gratings, the factors affecting mode selection within the cavity, proper alignment for optimal external feedback, optics setup for coarse and fine frequency sensitive measurements, a brief overview of laser locking techniques, and laser linewidth measurements are included.

An Overview of the MAGIC Project

DTIC Science & Technology

1993-12-01

unlimnitedj_ _______ 13. ABSTRACT (Mxmwn WO0 words) This note provides an overview of the MAGIC project1 which is developing a high-speed, wide-area...298Rv.9 16. PRICE COASSDE 3.1 17. SEURITY18. SEURITY19. SEURITY2930.2BIA NO An Overview of the M 93B0000173 MAGIC Project December 1993 Barbara B...Intelligence Division ii ABSTRACT This note provides an overview of the MAGIC project, which is developing a high-speed, wide- area networking testbed

Overview of SBIR Phase II Work on Hollow Graphite Fibers

NASA Technical Reports Server (NTRS)

Stallcup, Michael; Brantley, Lott W. (Technical Monitor)

2001-01-01

Ultra-Lightweight materials are enabling for producing space based optical components and support structures. Heretofore, innovative designs using existing materials has been the approach to produce lighter-weight optical systems. Graphite fiber reinforced composites, because of their light weight, have been a material of frequent choice to produce space based optical components. Hollow graphite fibers would be lighter than standard solid graphite fibers and, thus, would save weight in optical components. The Phase I SBIR program demonstrated it is possible to produce hollow carbon fibers that have strengths up to 4.2 GPa which are equivalent to commercial fibers, and composites made from the hollow fibers had substantially equivalent composite strengths as commercial fiber composites at a 46% weight savings. The Phase II SBIR program will optimize processing and properties of the hollow carbon fiber and scale-up processing to produce sufficient fiber for fabricating a large ultra-lightweight mirror for delivery to NASA. Information presented here includes an overview of the strength of some preliminary hollow fibers, photographs of those fibers, and a short discussion of future plans.

Overview of online two-dimensional liquid chromatography based on cell membrane chromatography for screening target components from traditional Chinese medicines.

PubMed

Muhammad, Saqib; Han, Shengli; Xie, Xiaoyu; Wang, Sicen; Aziz, Muhammad Majid

2017-01-01

Cell membrane chromatography is a simple, specific, and time-saving technique for studying drug-receptor interactions, screening of active components from complex mixtures, and quality control of traditional Chinese medicines. However, the short column life, low sensitivity, low column efficiency (so cannot resolve satisfactorily mixture of compounds), low peak capacity, and inefficient in structure identification were bottleneck in its application. Combinations of cell membrane chromatography with multidimensional chromatography such as two-dimensional liquid chromatography and high sensitivity detectors like mass have significantly reduced many of the above-mentioned shortcomings. This paper provides an overview of the current advances in online two-dimensional-based cell membrane chromatography for screening target components from traditional Chinese medicines with particular emphasis on the instrumentation, preparation of cell membrane stationary phase, advantages, and disadvantages compared to alternative approaches. The last section of the review summarizes the applications of the online two-dimensional high-performance liquid chromatography based cell membrane chromatography reported since its emergence to date (2010-June 2016). © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Flexible design in water and wastewater engineering--definitions, literature and decision guide.

PubMed

Spiller, Marc; Vreeburg, Jan H G; Leusbrock, Ingo; Zeeman, Grietje

2015-02-01

Urban water and wastewater systems face uncertain developments including technological progress, climate change and urban development. To ensure the sustainability of these systems under dynamic conditions it has been proposed that technologies and infrastructure should be flexible, adaptive and robust. However, in literature it is often unclear what these technologies and infrastructure are. Furthermore, the terms flexible, adaptive and robust are often used interchangeably, despite important differences. In this paper we will i) define the terminology, ii) provide an overview of the status of flexible infrastructure design alternatives for water and wastewater networks and treatment, and iii) develop guidelines for the selection of flexible design alternatives. Results indicate that, with the exception of Net Present Valuation methods, there is little research available on the design and evaluation of technologies that can enable flexibility. Flexible design alternatives reviewed include robust design, phased design, modular design, modular/component platform design and design for remanufacturing. As developments in the water sector are driven by slow variables (climate change, urban development), rather than market forces, it is suggested that phased design or component platform designs are suitable for responding to change, while robust design is an option when operations face highly dynamic variability. Copyright © 2014 Elsevier Ltd. All rights reserved.

NASA Docking System (NDS) Users Guide: International Space Station Program. Type 4

NASA Technical Reports Server (NTRS)

Tabakman, Alexander

2010-01-01

The NASA Docking System (NDS) Users Guide provides an overview of the basic information needed to integrate the NDS onto a Host Vehicle (HV). This Users Guide is intended to provide a vehicle developer with a fundamental understanding of the NDS technical and operations information to support their program and engineering integration planning. The Users Guide identifies the NDS Specification, Interface Definition or Requirement Documents that contain the complete technical details and requirements that a vehicle developer must use to design, develop and verify their systems will interface with NDS. This Guide is an initial reference and must not be used as a design document. In the event of conflict between this Users Guide and other applicable interface definition or requirements documents; the applicable document will take precedence. This Users Guide is organized in three main sections. Chapter 1 provides an overview of the NDS and CDA hardware and the operations concepts for the NDS. Chapter 2 provides information for Host Vehicle Program integration with the NDS Project Office. Chapter 2 describes the NDS Project organization, integration and verification processes, user responsibilities, and specification and interface requirement documents. Chapter 3 provides a summary of basic technical information for the NDS design. Chapter 3 includes NDS hardware component descriptions, physical size and weight characteristics, and summary of the capabilities and constraints for the various NDS sub-systems.

The development of interior noise and vibration criteria

NASA Technical Reports Server (NTRS)

Leatherwood, J. D.; Clevenson, S. A.; Stephens, D. G.

1990-01-01

A generalized model was developed for estimating passenger discomfort response to combined noise and vibration. This model accounts for broadband noise and vibration spectra and multiple axes of vibration as well as the interactive effects of combined noise and vibration. The model has the unique capability of transforming individual components of noise/vibration environment into subjective comfort units and then combining these comfort units to produce a total index of passenger discomfort and useful sub-indices that typify passenger comfort within the environment. An overview of the model development is presented including the methodology employed, major elements of the model, model applications, and a brief description of a commercially available portable ride comfort meter based directly upon the model algorithms. Also discussed are potential criteria formats that account for the interactive effects of noise and vibration on human discomfort response.

Hericium erinaceus (Yamabushitake): a unique resource for developing functional foods and medicines.

PubMed

Wang, Mingxing; Gao, Yang; Xu, Duoduo; Konishi, Tetsuya; Gao, Qipin

2014-12-01

Hericium erinaceus (HE) is a fungus inhabiting the mountainous areas of the northeast territories in Asia. HE has been used in traditional folk medicine and medicinal cuisine in China, Korea and Japan. Evidence has been adduced for a variety of physiological effects, including anti-aging, anti-cancer, anti-gastritis, and anti-metabolic disease properties. Hence, HE is an attractive target resource for developing not only medicines, but also functional foods. Basic studies on the physiological functions of HE and on the chemical identification of its active ingredients have progressed in recent decades. In this article, we provide an overview of the biochemical and pharmacological studies on HE, especially of its antitumor and neuroprotective functions, together with a survey of recent developments in the chemical analysis of its polysaccharides, which comprise its major active components.

An Overview of Carbon Nanotubes and Graphene for Biosensing Applications

NASA Astrophysics Data System (ADS)

Zhu, Zanzan

2017-07-01

With the development of carbon nanomaterials in recent years, there has been an explosion of interests in using carbon nanotubes (CNTs) and graphene for developing new biosensors. It is believed that employing CNTs and graphene as sensor components can make sensors more reliable, accurate, and fast due to their remarkable properties. Depending on the types of target molecular, different strategies can be applied to design sensor device. This review article summarized the important progress in developing CNT- and graphene-based electrochemical biosensors, field-effect transistor biosensors, and optical biosensors. Although CNTs and graphene have led to some groundbreaking discoveries, challenges are still remained and the state-of-the-art sensors are far from a practical application. As a conclusion, future effort has to be made through an interdisciplinary platform, including materials science, biology, and electric engineering.

Development of Metal Matrix Composites for NASA's Advanced Propulsion Systems

NASA Technical Reports Server (NTRS)

Lee, J.; Elam, S.

2001-01-01

The state-of-the-art development of several Metal Matrix Composites (MMC) for NASA's advanced propulsion systems will be presented. The goal is to provide an overview of NASA-Marshall Space Flight Center's on-going activities in MMC components for advanced liquid rocket engines such as the X-33 vehicle's Aerospike engine and X-34's Fastrac engine. The focus will be on lightweight, low cost, and environmental compatibility with oxygen and hydrogen of key MMC materials, within each of NASA's new propulsion application, that will provide a high payoff for NASA's Reusable Launch Vehicles and space access vehicles. In order to fabricate structures from MMC, effective joining methods must be developed to join MMC to the same or to different monolithic alloys. Therefore, a qualitative assessment of MMC's welding and joining techniques will be outlined.

Advanced MCT technologies at LETI for space applications

NASA Astrophysics Data System (ADS)

Durand, A.; Destefanis, G.; Gravrand, O.; Rothmann, J.

This document is a recap of an oral presentation made at Nice during the INSU Astrophysics Detector Workshop 2008. It aims at giving an overview of the achievements and ongoing developments presently carried out at CEA-LETI in the field of Infrared focal plane array. Although most of the research actually performed at LETI is not driven by space oriented application, the excellence and the cutting edge of the outcome is or can be applied to space-dedicated components. This paper focus on features and developments from which astrophysics observation would benefit in the near future on the European market. This encompassed “traditionnal” developments such as format enlargement, low dark current technology such as p/n structure but it also shade light on promising and thrilling development such as avalanche photodiode array. It eventually gives some hints of none MCT technologies processed at LETI.

SERVIR Science Applications for Capacity Building

NASA Technical Reports Server (NTRS)

Limaye, Ashutosh; Searby, Nancy D.; Irwin, Daniel

2012-01-01

SERVIR is a regional visualization and monitoring system using Earth observations to support environmental management, climate adaptation, and disaster response in developing countries. SERVIR is jointly sponsored by NASA and the U.S. Agency for International Development (USAID). SERVIR has been instrumental in development of science applications to support the decision-making and capacity building in the developing countries with the help of SERVIR Hubs. In 2011, NASA Research Opportunities in Space and Earth Sciences (ROSES) included a call for proposals to form SERVIR Applied Sciences Team (SERVIR AST) under Applied Sciences Capacity Building Program. Eleven proposals were selected, the Principal Investigators of which comprise the core of the SERVIR AST. The expertise on the Team span several societal benefit areas including agriculture, disasters, public health and air quality, water, climate and terrestrial carbon assessments. This presentation will cover the existing SERVIR science applications, capacity building components, overview of SERVIR AST projects, and anticipated impacts.

High Temperature Joining and Characterization of Joint Properties in Silicon Carbide-Based Composite Materials

NASA Technical Reports Server (NTRS)

Halbig, Michael C.; Singh, Mrityunjay

2015-01-01

Advanced silicon carbide-based ceramics and composites are being developed for a wide variety of high temperature extreme environment applications. Robust high temperature joining and integration technologies are enabling for the fabrication and manufacturing of large and complex shaped components. The development of a new joining approach called SET (Single-step Elevated Temperature) joining will be described along with the overview of previously developed joining approaches including high temperature brazing, ARCJoinT (Affordable, Robust Ceramic Joining Technology), diffusion bonding, and REABOND (Refractory Eutectic Assisted Bonding). Unlike other approaches, SET joining does not have any lower temperature phases and will therefore have a use temperature above 1315C. Optimization of the composition for full conversion to silicon carbide will be discussed. The goal is to find a composition with no remaining carbon or free silicon. Green tape interlayers were developed for joining. Microstructural analysis and preliminary mechanical tests of the joints will be presented.

Summative Evaluation Findings from the Interstellar Boundary Explorer (IBEX) Education and Public Outreach Program

NASA Astrophysics Data System (ADS)

Bartolone, L.; Nichols-Yehling, M.; Davis, H. B.; Davey, B.

2014-07-01

The Interstellar Boundary Explorer mission includes a comprehensive Education and Public Outreach (EPO) program in heliophysics that is overseen and implemented by the Adler Planetarium and evaluated by Technology for Learning Consortium, Inc. Several components of the IBEX EPO program were developed during the prime phase of the mission that were specifically designed for use in informal institutions, especially museums and planetaria. The program included a widely distributed planetarium show with accompanying informal education activities, printed posters, lithographs and other resources, funding for the development of the GEMS Space Science Sequence for Grades 6-8 curriculum materials, development of the IBEX mission website, development of materials for people with special needs, participation in the Heliophysics Educator Ambassador program, and support for the Space Explorers Afterschool Science Club for Chicago Public Schools. In this paper, we present an overview of the IBEX EPO program summative evaluation techniques and results for 2008 through 2012.

Assessment of Lithium-based Battery Electrolytes Developed under the NASA PERS Program

NASA Technical Reports Server (NTRS)

Bennett, William R.; Baldwin, Richard S.

2006-01-01

Recently, NASA formally completed the Polymer Energy Rechargeable System (PERS) Program, which was established in 2000 in collaboration with the Air Force Research Laboratory (AFRL) to support the development of polymer-based, lithium-based cell chemistries and battery technologies to address the next generation of aerospace applications and mission needs. The goal of this program was to ultimately develop an advanced, space-qualified battery technology, which embodied a solid polymer electrolyte (SPE) and complementary components, with improved performance characteristics that would address future aerospace battery requirements. Programmatically, the PERS initiative exploited both interagency collaborations to address common technology and engineering issues and the active participation of academia and private industry. The initial program phases focused on R&D activities to address the critical technical issues and challenges at the cell level. A variety of cell and polymeric electrolyte concepts were pursued as part of the development efforts undertaken at numerous governmental, industrial and academic laboratories. Numerous candidate electrolyte materials were developed, synthesized and optimized for evaluation. Utilizing the component screening facility and the "standardized" test procedures developed at the NASA Glenn Research Center, electrochemical screening and performance evaluations of promising candidate materials were completed. This overview summarizes test results for a variety of candidate electrolyte materials that were developed under the PERS Program. Electrolyte properties are contrasted and compared to the original project goals, and the strengths and weaknesses of the electrolyte chemistries are discussed. Limited cycling data for full-cells using lithium metal and vanadium oxide electrodes are also presented. Based on measured electrolyte properties, the projected performance characteristics and temperature limitations of batteries utilizing the advanced electrolytes and components have been estimated. Limitations for the achievement of practical performance levels are also discussed, as well as needs for future research and development.

PVMaT 1998 overview

NASA Astrophysics Data System (ADS)

Mittchell, Richard L.; Symko-Davies, Martha; Thomas, Holly P.; Witt, C. Edwin

1999-03-01

The Photovoltaic Manufacturing Technology (PVMaT) Project is a government/industry research and development (R&D) partnership between the U.S. federal government (through the U.S. Department of Energy [DOE]) and members of the U.S. PV industry. The goals of PVMaT are to assist the U.S. PV industry improve module manufacturing processes and equipment; accelerate manufacturing cost reductions for PV modules, balance-of-systems components, and integrated systems; increase commercial product performance and reliability; and enhance investment opportunities for substantial scale-ups of U.S.-based PV manufacturing plant capacities. The approach for PVMaT has been to cost-share the R&D risk as industry explores new manufacturing options and ideas for improved PV modules and components, advances system and product integration, and develops new system designs. These activities will lead to overall reduced system life-cycle costs for reliable PV end-products. The 1994 PVMaT Product-Driven BOS and Systems activities, as well as Product-Driven Module Manufacturing R&D activities, are just being completed. Fourteen new subcontracts have just been awarded in the areas of PV System and Component Technology and Module Manufacturing Technology. Government funding, subcontractor cost-sharing, and a comparison of the relative efforts by PV technology throughout the PVMaT project are also discussed.

Briefing book: Major projects in the upstream, downstream, petrochemical and power sectors of Vietnam. Final definitional mission report. Export trade information

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-04-06

The purpose of the briefing book is to provide project information to U.S. Businesses who seek cooperative partnerships with Vietnamese officials on a number of major development projects. The report is divided into the following sections: (1) Executive Summary; (2) Overview of Vietnam; (3) Overview of the Upstream Sector; (4) Overview of the Downstream Sector; (5) Overview of the Petrochemical Sector; (6) Overview of the Electric Energy Sector; (7) Project Development Processes; (8) Project Financing; (9) Foreign Competition and U.S. Competitiveness; (10) Project Profiles; (11) Key Contracts; (12) U.S. Commercial Service.

A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice

PubMed Central

Maupin, Kevin A.; Droscha, Casey J.; Williams, Bart O.

2013-01-01

The Wnt signaling pathway plays key roles in differentiation and development and alterations in this signaling pathway are causally associated with numerous human diseases. While several laboratories were examining roles for Wnt signaling in skeletal development during the 1990s, interest in the pathway rose exponentially when three key papers were published in 2001–2002. One report found that loss of the Wnt co-receptor, Low-density lipoprotein related protein-5 (LRP5), was the underlying genetic cause of the syndrome Osteoporosis pseudoglioma (OPPG). OPPG is characterized by early-onset osteoporosis causing increased susceptibility to debilitating fractures. Shortly thereafter, two groups reported that individuals carrying a specific point mutation in LRP5 (G171V) develop high-bone mass. Subsequent to this, the causative mechanisms for these observations heightened the need to understand the mechanisms by which Wnt signaling controlled bone development and homeostasis and encouraged significant investment from biotechnology and pharmaceutical companies to develop methods to activate Wnt signaling to increase bone mass to treat osteoporosis and other bone disease. In this review, we will briefly summarize the cellular mechanisms underlying Wnt signaling and discuss the observations related to OPPG and the high-bone mass disorders that heightened the appreciation of the role of Wnt signaling in normal bone development and homeostasis. We will then present a comprehensive overview of the core components of the pathway with an emphasis on the phenotypes associated with mice carrying genetically engineered mutations in these genes and clinical observations that further link alterations in the pathway to changes in human bone. PMID:26273492

Formative research methods for designing culturally appropriate, integrated child nutrition and development interventions: an overview.

PubMed

Bentley, Margaret E; Johnson, Susan L; Wasser, Heather; Creed-Kanashiro, Hilary; Shroff, Monal; Fernandez Rao, Sylvia; Cunningham, Melissa

2014-01-01

Nutritional and developmental insults in the first few years of life have profound public health implications, including substantial contributions to neonatal, infant, and early childhood morbidity and mortality, as well as longer term effects on cognitive development, school achievement, and worker productivity. Optimal development that can lead to the attainment of an individual's fullest potential, therefore, requires a combination of genetic capacity, adequate nutrition, psychosocial stimulation, and safe, clean physical environments. Researchers and policymakers have called for integrated child nutrition and development interventions for more than 20 years, yet there are only a handful of efficacy trials and even fewer examples of integrated interventions that have been taken to scale. While a critical component in the design of such interventions is formative research, there is a dearth of information in both the literature and policy arenas to guide this phase of the process. To move the field forward, this paper first provides an overview of formative research methods with a focus on qualitative inquiry, a description of the critical domains to be assessed (infant and young child feeding, responsive feeding, and child development), and currently available resources. Application of these methods is provided through a real-world case study--the design of an integrated nutrition and child development efficacy trial in Andhra Pradesh, India. Recommendations for next steps are discussed, the most important of which is the need for a comprehensive set of formative guidelines for designing locally tailored, culturally appropriate, integrated interventions. © 2013 New York Academy of Sciences.

Design, Analysis and Fabrication of Secondary Structural Components for the Habitat Demonstration Unit-Deep Space Habitat

NASA Technical Reports Server (NTRS)

Smith, Russell W.; Langford, William M.

2012-01-01

In support of NASA s Habitat Demonstration Unit - Deep Space Habitat Prototype, a number of evolved structural sections were designed, fabricated, analyzed and installed in the 5 meter diameter prototype. The hardware consisted of three principal structural sections, and included the development of novel fastener insert concepts. The articles developed consisted of: 1) 1/8th of the primary flooring section, 2) an inner radius floor beam support which interfaced with, and supported (1), 3) two upper hatch section prototypes, and 4) novel insert designs for mechanical fastener attachments. Advanced manufacturing approaches were utilized in the fabrication of the components. The structural components were developed using current commercial aircraft constructions as a baseline (for both the flooring components and their associated mechanical fastener inserts). The structural sections utilized honeycomb sandwich panels. The core section consisted of 1/8th inch cell size Nomex, at 9 lbs/cu ft, and which was 0.66 inches thick. The facesheets had 3 plys each, with a thickness of 0.010 inches per ply, made from woven E-glass with epoxy reinforcement. Analysis activities consisted of both analytical models, as well as initial closed form calculations. Testing was conducted to help verify analysis model inputs, as well as to facilitate correlation between testing and analysis. Test activities consisted of both 4 point bending tests as well as compressive core crush sequences. This paper presents an overview of this activity, and discusses issues encountered during the various phases of the applied research effort, and its relevance to future space based habitats.

EPIC : expedited processing at international crossings : evaluation final report

DOT National Transportation Integrated Search

1998-09-01

This executive summary presents an overview of the Expedited Processing at International Crossings (EPIC) Field Operational Test (FOT). The EPIC focus was on the commercial vehicle transport component of international border crossings at the Nogales,...

Fundamentals of Ground-Water Modeling

EPA Pesticide Factsheets

This paper presents an overview of the essential components of ground-water flow and contaminant transport modeling in saturated porous media. While fractured rocks and fractured porous rocks may behave like porous media with respect to many flow and...

Students as Citizen Scientists - Earth Conservation Corps

EPA Pesticide Factsheets

This document has an overview of the student workshops on water quality monitoring used to generate citizen scientists. It also includes the main components of the curriculum and contact information for the Earth Conservation Corps to interested parties.

AIAA spacecraft GN&C interface standards initiative: Overview

NASA Technical Reports Server (NTRS)

Challoner, A. Dorian

1995-01-01

The American Institute of Aeronautics and Astronautics (AIAA) has undertaken an important standards initiative in the area of spacecraft guidance, navigation, and control (GN&C) subsystem interfaces. The objective of this effort is to establish standards that will promote interchangeability of major GN&C components, thus enabling substantially lower spacecraft development costs. Although initiated by developers of conventional spacecraft GN&C, it is anticipated that interface standards will also be of value in reducing the development costs of micro-engineered spacecraft. The standardization targets are specifically limited to interfaces only, including information (i.e. data and signal), power, mechanical, thermal, and environmental interfaces between various GN&C components and between GN&C subsystems and other subsystems. The current emphasis is on information interfaces between various hardware elements (e.g., between star trackers and flight computers). The poster presentation will briefly describe the program, including the mechanics and schedule, and will publicize the technical products as they exist at the time of the conference. In particular, the rationale for the adoption of the AS1773 fiber-optic serial data bus and the status of data interface standards at the application layer will be presented.

Protozoan Parasites in Drinking Water: A System Approach for Improved Water, Sanitation and Hygiene in Developing Countries

PubMed Central

Tussupova, Kamshat; Berndtsson, Ronny; Sharapatova, Kulyash

2018-01-01

Improved water, sanitation and hygiene (WASH) are significant in preventing diarrhea morbidity and mortality caused by protozoa in low- and middle-income countries. Due to the intimate and complex relationships between the different WASH components, it is often necessary to improve not just one but all of these components to have sustainable results. The objective of this paper was to review the current state of WASH-related health problems caused by parasitic protozoa by: giving an overview and classification of protozoa and their effect on people’s health, discussing different ways to improve accessibility to safe drinking water, sanitation services and personal hygiene behavior; and suggesting an institutional approach to ensure improved WASH. The findings indicate that Giardia and Cryptosporidium are more often identified during waterborne or water-washed outbreaks and they are less sensitive than most of the bacteria and viruses to conventional drinking water and wastewater treatment methods. There are various institutions of control and prevention of water-related diseases caused by protozoa in developed countries. Unfortunately, the developing regions do not have comparable systems. Consequently, the institutional and systems approach to WASH is necessary in these countries. PMID:29534511

Protozoan Parasites in Drinking Water: A System Approach for Improved Water, Sanitation and Hygiene in Developing Countries.

PubMed

Omarova, Alua; Tussupova, Kamshat; Berndtsson, Ronny; Kalishev, Marat; Sharapatova, Kulyash

2018-03-12

Improved water, sanitation and hygiene (WASH) are significant in preventing diarrhea morbidity and mortality caused by protozoa in low- and middle-income countries. Due to the intimate and complex relationships between the different WASH components, it is often necessary to improve not just one but all of these components to have sustainable results. The objective of this paper was to review the current state of WASH-related health problems caused by parasitic protozoa by: giving an overview and classification of protozoa and their effect on people's health, discussing different ways to improve accessibility to safe drinking water, sanitation services and personal hygiene behavior; and suggesting an institutional approach to ensure improved WASH. The findings indicate that Giardia and Cryptosporidium are more often identified during waterborne or water-washed outbreaks and they are less sensitive than most of the bacteria and viruses to conventional drinking water and wastewater treatment methods. There are various institutions of control and prevention of water-related diseases caused by protozoa in developed countries. Unfortunately, the developing regions do not have comparable systems. Consequently, the institutional and systems approach to WASH is necessary in these countries.

Military, Charter, Unreported Domestic Traffic and General Aviation 1976, 1984, 1992, and 2015 Emission Scenarios

NASA Technical Reports Server (NTRS)

Mortlock, Alan; VanAlstyne, Richard

1998-01-01

The report describes development of databases estimating aircraft engine exhaust emissions for the years 1976 and 1984 from global operations of Military, Charter, historic Soviet and Chinese, Unreported Domestic traffic, and General Aviation (GA). These databases were developed under the National Aeronautics and Space Administration's (NASA) Advanced Subsonic Assessment (AST). McDonnell Douglas Corporation's (MDC), now part of the Boeing Company has previously estimated engine exhaust emissions' databases for the baseline year of 1992 and a 2015 forecast year scenario. Since their original creation, (Ward, 1994 and Metwally, 1995) revised technology algorithms have been developed. Additionally, GA databases have been created and all past NIDC emission inventories have been updated to reflect the new technology algorithms. Revised data (Baughcum, 1996 and Baughcum, 1997) for the scheduled inventories have been used in this report to provide a comparison of the total aviation emission forecasts from various components. Global results of two historic years (1976 and 1984), a baseline year (1992) and a forecast year (2015) are presented. Since engine emissions are directly related to fuel usage, an overview of individual aviation annual global fuel use for each inventory component is also given in this report.

Overview of microoptics: Past, present, and future

NASA Technical Reports Server (NTRS)

Veldkamp, Wilfrid B.

1993-01-01

Through advances in semiconductor miniaturization technology, microrelief patterns, with characteristic dimensions as small as the wavelength of light, can now be mass reproduced to form high-quality and low-cost optical components. In a unique example of technology transfer, from electronics to optics, this capability is allowing optics designers to create innovative optical components that promise to solve key problems in optical sensors, optical communication channels, and optical processors.

Semiconductor devices for entangled photon pair generation: a review

NASA Astrophysics Data System (ADS)

Orieux, Adeline; Versteegh, Marijn A. M.; Jöns, Klaus D.; Ducci, Sara

2017-07-01

Entanglement is one of the most fascinating properties of quantum mechanical systems; when two particles are entangled the measurement of the properties of one of the two allows the properties of the other to be instantaneously known, whatever the distance separating them. In parallel with fundamental research on the foundations of quantum mechanics performed on complex experimental set-ups, we assist today with bourgeoning of quantum information technologies bound to exploit entanglement for a large variety of applications such as secure communications, metrology and computation. Among the different physical systems under investigation, those involving photonic components are likely to play a central role and in this context semiconductor materials exhibit a huge potential in terms of integration of several quantum components in miniature chips. In this article we review the recent progress in the development of semiconductor devices emitting entangled photons. We will present the physical processes allowing the generation of entanglement and the tools to characterize it; we will give an overview of major recent results of the last few years and highlight perspectives for future developments.

The Virtual Environment for Reactor Applications (VERA): Design and architecture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Turner, John A.; Clarno, Kevin; Sieger, Matt

VERA, the Virtual Environment for Reactor Applications, is the system of physics capabilities being developed and deployed by the Consortium for Advanced Simulation of Light Water Reactors (CASL), the first DOE Hub, which was established in July 2010 for the modeling and simulation of commercial nuclear reactors. VERA consists of integrating and interfacing software together with a suite of physics components adapted and/or refactored to simulate relevant physical phenomena in a coupled manner. VERA also includes the software development environment and computational infrastructure needed for these components to be effectively used. We describe the architecture of VERA from both amore » software and a numerical perspective, along with the goals and constraints that drove the major design decisions and their implications. As a result, we explain why VERA is an environment rather than a framework or toolkit, why these distinctions are relevant (particularly for coupled physics applications), and provide an overview of results that demonstrate the application of VERA tools for a variety of challenging problems within the nuclear industry.« less

Public health laboratory quality management in a developing country.

PubMed

Wangkahat, Khwanjai; Nookhai, Somboon; Pobkeeree, Vallerut

2012-01-01

The article aims to give an overview of the system of public health laboratory quality management in Thailand and to produce a strengths, weaknesses, opportunities and threats (SWOT) analysis that is relevant to public health laboratories in the country. The systems for managing laboratory quality that are currently employed were described in the first component. The second component was a SWOT analysis, which used the opinions of laboratory professionals to identify any areas that could be improved to meet quality management systems. Various quality management systems were identified and the number of laboratories that met both international and national quality management requirements was different. The SWOT analysis found the opportunities and strengths factors offered the best chance to improve laboratory quality management in the country. The results are based on observations and brainstorming with medical laboratory professionals who can assist laboratories in accomplishing quality management. The factors derived from the analysis can help improve laboratory quality management in the country. This paper provides viewpoints and evidence-based approaches for the development of best possible practice of services in public health laboratories.

Implementation of neuromorphic systems: from discrete components to analog VLSI chips (testing and communication issues).

PubMed

Dante, V; Del Giudice, P; Mattia, M

2001-01-01

We review a series of implementations of electronic devices aiming at imitating to some extent structure and function of simple neural systems, with particular emphasis on communication issues. We first provide a short overview of general features of such "neuromorphic" devices and the implications of setting up "tests" for them. We then review the developments directly related to our work at the Istituto Superiore di Sanità (ISS): a pilot electronic neural network implementing a simple classifier, autonomously developing internal representations of incoming stimuli; an output network, collecting information from the previous classifier and extracting the relevant part to be forwarded to the observer; an analog, VLSI (very large scale integration) neural chip implementing a recurrent network of spiking neurons and plastic synapses, and the test setup for it; a board designed to interface the standard PCI (peripheral component interconnect) bus of a PC with a special purpose, asynchronous bus for communication among neuromorphic chips; a short and preliminary account of an application-oriented device, taking advantage of the above communication infrastructure.

Overview of Intelligent Systems and Operations Development

NASA Technical Reports Server (NTRS)

Pallix, Joan; Dorais, Greg; Penix, John

2004-01-01

To achieve NASA's ambitious mission objectives for the future, aircraft and spacecraft will need intelligence to take the correct action in a variety of circumstances. Vehicle intelligence can be defined as the ability to "do the right thing" when faced with a complex decision-making situation. It will be necessary to implement integrated autonomous operations and low-level adaptive flight control technologies to direct actions that enhance the safety and success of complex missions despite component failures, degraded performance, operator errors, and environment uncertainty. This paper will describe the array of technologies required to meet these complex objectives. This includes the integration of high-level reasoning and autonomous capabilities with multiple subsystem controllers for robust performance. Future intelligent systems will use models of the system, its environment, and other intelligent agents with which it interacts. They will also require planners, reasoning engines, and adaptive controllers that can recommend or execute commands enabling the system to respond intelligently. The presentation will also address the development of highly dependable software, which is a key component to ensure the reliability of intelligent systems.

The Virtual Environment for Reactor Applications (VERA): Design and architecture

DOE PAGES

Turner, John A.; Clarno, Kevin; Sieger, Matt; ...

2016-09-08

VERA, the Virtual Environment for Reactor Applications, is the system of physics capabilities being developed and deployed by the Consortium for Advanced Simulation of Light Water Reactors (CASL), the first DOE Hub, which was established in July 2010 for the modeling and simulation of commercial nuclear reactors. VERA consists of integrating and interfacing software together with a suite of physics components adapted and/or refactored to simulate relevant physical phenomena in a coupled manner. VERA also includes the software development environment and computational infrastructure needed for these components to be effectively used. We describe the architecture of VERA from both amore » software and a numerical perspective, along with the goals and constraints that drove the major design decisions and their implications. As a result, we explain why VERA is an environment rather than a framework or toolkit, why these distinctions are relevant (particularly for coupled physics applications), and provide an overview of results that demonstrate the application of VERA tools for a variety of challenging problems within the nuclear industry.« less

An overview of ITER diagnostics (invited)

NASA Astrophysics Data System (ADS)

Young, Kenneth M.; Costley, A. E.; ITER-JCT Home Team; ITER Diagnostics Expert Group

1997-01-01

The requirements for plasma measurements for operating and controlling the ITER device have now been determined. Initial criteria for the measurement quality have been set, and the diagnostics that might be expected to achieve these criteria have been chosen. The design of the first set of diagnostics to achieve these goals is now well under way. The design effort is concentrating on the components that interact most strongly with the other ITER systems, particularly the vacuum vessel, blankets, divertor modules, cryostat, and shield wall. The relevant details of the ITER device and facility design and specific examples of diagnostic design to provide the necessary measurements are described. These designs have to take account of the issues associated with very high 14 MeV neutron fluxes and fluences, nuclear heating, high heat loads, and high mechanical forces that can arise during disruptions. The design work is supported by an extensive research and development program, which to date has concentrated on the effects these levels of radiation might cause on diagnostic components. A brief outline of the organization of the diagnostic development program is given.

The writers guide to NASA. [NASA Centers and public affairs contacts

NASA Technical Reports Server (NTRS)

1978-01-01

NASA services of interest to writers and to the news media include personal interviews, daily audio reports of major missions, and projects via automated telephone, research assistance from historians or history monitors at technical libraries, the use of a collection of historical photographs, and the free loan of sound films of NASA research and development activities. The names and phones numbers are listed for public affairs contacts at Headquarters and at each of the major centers and their component installations. An overview of the six NASA program offices is included along with a vicinity map of each center and a description of their facilities and management responsibilities.

Overview of a stirling engine test project

NASA Technical Reports Server (NTRS)

Slaby, J. G.

1980-01-01

Tests were conducted on three Stirling engines ranging in size from 1.33 to 53 horsepower (1 to 40 kW). The tests were directed toward developing alternative, backup component concepts to improve engine efficiency and performance or to reduce costs. Some of the activities included investigating attractive concepts and materials for cooler-regenerator units, installing a jet impingement device on a Stirling engine to determine its potential for improved engine performance, and presenting performance maps for initial characterization of Stirling engines. The experiment results of the tests are presented along with predictions of results of future tests to be conducted on the Stirling engines.

Bragg spectroscopy of strongly interacting Fermi gases

NASA Astrophysics Data System (ADS)

Lingham, M. G.; Fenech, K.; Peppler, T.; Hoinka, S.; Dyke, P.; Hannaford, P.; Vale, C. J.

2016-10-01

This article provides an overview of recent developments and emerging topics in the study of two-component Fermi gases using Bragg spectroscopy. Bragg scattering is achieved by exposing a gas to two intersecting laser beams with a slight frequency difference and measuring the momentum transferred to the atoms. By varying the Bragg laser detuning, it is possible to measure either the density or spin response functions which characterize the basic excitations present in the gas. Specifically, one can measure properties such as the dynamic and static structure factors, Tan's universal contact parameter and observe signatures for the onset of pair condensation locally within a gas.

Biomimicry in metal-organic materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, MW; Gu, ZY; Bosch, M

2015-06-15

Nature has evolved a great number of biological molecules which serve as excellent constructional or functional units for metal-organic materials (MOMs). Even though the study of biomimetic MOMs is still at its embryonic stage, considerable progress has been made in the past few years. In this critical review, we will highlight the recent advances in the design, development and application of biomimetic MOMs, and illustrate how the incorporation of biological components into MOMs could further enrich their structural and functional diversity. More importantly, this review will provide a systematic overview of different methods for rational design of MOMs with biomimeticmore » features. Published by Elsevier B.V.« less

Hormones in pain modulation and their clinical implications for pain control: a critical review.

PubMed

Chen, Xueyin; Zhang, Jinyuan; Wang, Xiangrui

2016-07-01

Recently, more and more studies have found that pain generation, transmission and modulation are under hormonal regulation. Indeed, hormonal dysregulation is a common component of chronic pain syndromes. Studies have attempted to determine whether the relationship between the pain and its perception and hormones is a causative relationship and how these processes interrelate. This review summarizes and analyzes the current experimental data and provides an overview of the studies addressing these questions. The relationship between pain perception and endocrine effects suggests that hormones can be used as important biomarkers of chronic pain syndromes and/or be developed into therapeutic agents in the fight against pain.

Graphite/epoxy composite adapters for the Space Shuttle/Centaur vehicle

NASA Technical Reports Server (NTRS)

Kasper, Harold J.; Ring, Darryl S.

1990-01-01

The decision to launch various NASA satellite and Air Force spacecraft from the Space Shuttle created the need for a high-energy upper stage capable of being deployed from the cargo bay. Two redesigned versions of the Centaur vehicle which employed a graphite/epoxy composite material for the forward and aft adapters were selected. Since this was the first time a graphite/epoxy material was used for Centaur major structural components, the development of the adapters was a major effort. An overview of the composite adapter designs, subcomponent design evaluation test results, and composite adapter test results from a full-scale vehicle structural test is presented.

A Study on Aircraft Engine Control Systems for Integrated Flight and Propulsion Control

NASA Astrophysics Data System (ADS)

Yamane, Hideaki; Matsunaga, Yasushi; Kusakawa, Takeshi

A flyable FADEC system engineering model incorporating Integrated Flight and Propulsion Control (IFPC) concept is developed for a highly maneuverable aircraft and a fighter-class engine. An overview of the FADEC system and functional assignments for its components such as the Engine Control Unit (ECU) and the Integrated Control Unit (ICU) are described. Overall system reliability analysis, convex analysis and multivariable controller design for the engine, fault detection/redundancy management, and response characteristics of a fuel system are addressed. The engine control performance of the FADEC is demonstrated by hardware-in-the-loop simulation for fast acceleration and thrust transient characteristics.

Biomimetic Cross-Reactive Sensor Arrays: Prospects in Biodiagnostics

PubMed Central

Fitzgerald, J. E.

2016-01-01

Biomimetic cross-reactive sensor arrays have been used to detect and analyze a wide variety of vapour and liquid components in applications such as food science, public health and safety, and diagnostics. As technology has advanced over the past three decades, these systems have become selective, sensitive, and affordable. Currently, the need for non-invasive and accurate devices for early disease diagnosis remains a challenge. This review provides an overview of the various types of Biomimetic cross-reactive sensor arrays (also referred to as electronic noses and tongues in the literature), their current use and future directions, and an outlook for future technological development. PMID:28217300

The professional voice.

PubMed

Benninger, M S

2011-02-01

The human voice is not only the key to human communication but also serves as the primary musical instrument. Many professions rely on the voice, but the most noticeable and visible are singers. Care of the performing voice requires a thorough understanding of the interaction between the anatomy and physiology of voice production, along with an awareness of the interrelationships between vocalisation, acoustic science and non-vocal components of performance. This review gives an overview of the care and prevention of professional voice disorders by describing the unique and integrated anatomy and physiology of singing, the roles of development and training, and the importance of the voice care team.

Overview of MDX-A System for Medical Diagnosis

PubMed Central

Mittal, S.; Chandrasekaran, B.; Smith, J.

1979-01-01

We describe the design and performance of MDX, an experimental medical diagnosis system, which currently diagnoses in the syndrome called Cholestasis. The needed medical knowledge is represented in a scheme called conceptual structures, which can be viewed as a collection of conceptual experts interacting according to certain well-defined principles. MDX has three components: the diagnostic system, a patient data base and a radiology consultant. We describe these components, the inter-expert communication system and the query language used by these components. The system is illustrated by means of its performance on a real case.

The role and application of ion beam analysis for studies of plasma-facing components in controlled fusion devices

NASA Astrophysics Data System (ADS)

Rubel, Marek; Petersson, Per; Alves, Eduardo; Brezinsek, Sebastijan; Coad, Joseph Paul; Heinola, Kalle; Mayer, Matej; Widdowson, Anna

2016-03-01

First wall materials in controlled fusion devices undergo serious modification by several physical and chemical processes arising from plasma-wall interactions. Detailed information is required for the assessment of material lifetime and accumulation of hydrogen isotopes in wall materials. The intention of this work is to give a concise overview of key issues in the characterization of plasma-facing materials and components in tokamaks, especially in JET with an ITER-Like Wall. IBA techniques play a particularly prominent role here because of their isotope selectivity in the low-Z range (1-10), high sensitivity and combination of several methods in a single run. The role of 3He-based NRA, RBS (standard and micro-size beam) and HIERDA in fuel retention and material migration studies is presented. The use of tracer techniques with rare isotopes (e.g. 15N) or marker layers on wall diagnostic components is described. Special instrumentation, development of equipment to enhance research capabilities and issues in handling of contaminated materials are addressed.

Reliability Issues in Stirling Radioisotope Power Systems

NASA Technical Reports Server (NTRS)

Schreiber, Jeffrey; Shah, Ashwin

2005-01-01

Stirling power conversion is a potential candidate for use in a Radioisotope Power System (RPS) for space science missions because it offers a multifold increase in the conversion efficiency of heat to electric power and reduced requirement of radioactive material. Reliability of an RPS that utilizes Stirling power conversion technology is important in order to ascertain long term successful performance. Owing to long life time requirement (14 years), it is difficult to perform long-term tests that encompass all the uncertainties involved in the design variables of components and subsystems comprising the RPS. The requirement for uninterrupted performance reliability and related issues are discussed, and some of the critical areas of concern are identified. An overview of the current on-going efforts to understand component life, design variables at the component and system levels, and related sources and nature of uncertainties are also discussed. Current status of the 110 watt Stirling Radioisotope Generator (SRG110) reliability efforts is described. Additionally, an approach showing the use of past experience on other successfully used power systems to develop a reliability plan for the SRG110 design is outlined.

Reliability Issues in Stirling Radioisotope Power Systems

NASA Technical Reports Server (NTRS)

Shah, Ashwin R.; Schreiber, Jeffrey G.

2004-01-01

Stirling power conversion is a potential candidate for use in a Radioisotope Power System (RPS) for space science missions because it offers a multifold increase in the conversion efficiency of heat to electric power and reduced requirement of radioactive material. Reliability of an RPS that utilizes Stirling power conversion technology is important in order to ascertain long term successful performance. Owing to long life time requirement (14 years), it is difficult to perform long-term tests that encompass all the uncertainties involved in the design variables of components and subsystems comprising the RPS. The requirement for uninterrupted performance reliability and related issues are discussed, and some of the critical areas of concern are identified. An overview of the current on-going efforts to understand component life, design variables at the component and system levels, and related sources and nature of uncertainties are also discussed. Current status of the 110 watt Stirling Radioisotope Generator (SRG110) reliability efforts is described. Additionally, an approach showing the use of past experience on other successfully used power systems to develop a reliability plan for the SRG110 design is outlined.

Overview of the mutation spectrum in familial exudative vitreoretinopathy and Norrie disease with identification of 21 novel variants in FZD4, LRP5, and NDP.

PubMed

Nikopoulos, Konstantinos; Venselaar, Hanka; Collin, Rob W J; Riveiro-Alvarez, Rosa; Boonstra, F Nienke; Hooymans, Johanna M M; Mukhopadhyay, Arijit; Shears, Deborah; van Bers, Marleen; de Wijs, Ilse J; van Essen, Anthonie J; Sijmons, Rolf H; Tilanus, Mauk A D; van Nouhuys, C Erik; Ayuso, Carmen; Hoefsloot, Lies H; Cremers, Frans P M

2010-06-01

Wnt signaling is a crucial component of the cell machinery orchestrating a series of physiological processes such as cell survival, proliferation, and migration. Among the plethora of roles that Wnt signaling plays, its canonical branch regulates eye organogenesis and angiogenesis. Mutations in the genes encoding the low density lipoprotein receptor protein 5 (LRP5) and frizzled 4 (FZD4), acting as coreceptors for Wnt ligands, cause familial exudative vitreoretinopathy (FEVR). Moreover, mutations in the gene encoding NDP, a ligand for these Wnt receptors, cause Norrie disease and FEVR. Both FEVR and Norrie disease share similar phenotypic characteristics, including abnormal vascularization of the peripheral retina and formation of fibrovascular masses in the eye that can lead to blindness. In this mutation update, we report 21 novel variants for FZD4, LRP5, and NDP, and discuss the putative functional consequences of missense mutations. In addition, we provide a comprehensive overview of all previously published variants in the aforementioned genes and summarize the phenotypic characteristics in mouse models carrying mutations in the orthologous genes. The increasing molecular understanding of Wnt signaling, related to ocular development and blood supply, offers more tools for accurate disease diagnosis that may be important in the development of therapeutic interventions.

Overview of condition monitoring and operation control of electric power conversion systems in direct-drive wind turbines under faults

NASA Astrophysics Data System (ADS)

Huang, Shoudao; Wu, Xuan; Liu, Xiao; Gao, Jian; He, Yunze

2017-09-01

Electric power conversion system (EPCS), which consists of a generator and power converter, is one of the most important subsystems in a direct-drive wind turbine (DD-WT). However, this component accounts for the most failures (approximately 60% of the total number) in the entire DD-WT system according to statistical data. To improve the reliability of EPCSs and reduce the operation and maintenance cost of DD-WTs, numerous researchers have studied condition monitoring (CM) and fault diagnostics (FD). Numerous CM and FD techniques, which have respective advantages and disadvantages, have emerged. This paper provides an overview of the CM, FD, and operation control of EPCSs in DD-WTs under faults. After introducing the functional principle and structure of EPCS, this survey discusses the common failures in wind generators and power converters; briefly reviewed CM and FD methods and operation control of these generators and power converters under faults; and discussed the grid voltage faults related to EPCSs in DD-WTs. These theories and their related technical concepts are systematically discussed. Finally, predicted development trends are presented. The paper provides a valuable reference for developing service quality evaluation methods and fault operation control systems to achieve high-performance and high-intelligence DD-WTs.

An Overview of Spray Modeling With OpenNCC and its Application to Emissions Predictions of a LDI Combustor at High Pressure

NASA Technical Reports Server (NTRS)

Raju, M. S.

2016-01-01

The open national combustion code (Open- NCC) is developed with the aim of advancing the current multi-dimensional computational tools used in the design of advanced technology combustors. In this paper we provide an overview of the spray module, LSPRAY-V, developed as a part of this effort. The spray solver is mainly designed to predict the flow, thermal, and transport properties of a rapidly evaporating multi-component liquid spray. The modeling approach is applicable over a wide-range of evaporating conditions (normal, superheat, and supercritical). The modeling approach is based on several well-established atomization, vaporization, and wall/droplet impingement models. It facilitates large-scale combustor computations through the use of massively parallel computers with the ability to perform the computations on either structured & unstructured grids. The spray module has a multi-liquid and multi-injector capability, and can be used in the calculation of both steady and unsteady computations. We conclude the paper by providing the results for a reacting spray generated by a single injector element with 600 axially swept swirler vanes. It is a configuration based on the next-generation lean-direct injection (LDI) combustor concept. The results include comparisons for both combustor exit temperature and EINOX at three different fuel/air ratios.

Hand Rehabilitation Robotics on Poststroke Motor Recovery

PubMed Central

2017-01-01

The recovery of hand function is one of the most challenging topics in stroke rehabilitation. Although the robot-assisted therapy has got some good results in the latest decades, the development of hand rehabilitation robotics is left behind. Existing reviews of hand rehabilitation robotics focus either on the mechanical design on designers' view or on the training paradigms on the clinicians' view, while these two parts are interconnected and both important for designers and clinicians. In this review, we explore the current literature surrounding hand rehabilitation robots, to help designers make better choices among varied components and thus promoting the application of hand rehabilitation robots. An overview of hand rehabilitation robotics is provided in this paper firstly, to give a general view of the relationship between subjects, rehabilitation theories, hand rehabilitation robots, and its evaluation. Secondly, the state of the art hand rehabilitation robotics is introduced in detail according to the classification of the hardware system and the training paradigm. As a result, the discussion gives available arguments behind the classification and comprehensive overview of hand rehabilitation robotics. PMID:29230081

An overview of active flow control actuators and applications (presentation video)

NASA Astrophysics Data System (ADS)

Brzozowski, Daniel; Whalen, Edward A.

2014-04-01

Active Flow Control (AFC) is an emerging technology which promises performance enhancements to both military and civilian aircraft. A technique which uses energy input at discrete locations to manipulate the flow over an aerodynamic surface, AFC may be used to reduce drag, prevent flow separation, and enable otherwise-infeasible aerodynamic designs. Additional applications include shear layer and turbulence control for aero-optics applications and mixing enhancement for thermal applications. Many AFC applications call for a high frequency fluidic perturbation provided by an electrically-powered actuator. In these instances, piezoelectric (PZT) materials have served as the workhorse for flow control actuators, such as the widely-studied synthetic jet. Because the PZT materials form the critical component of the actuator, the maximum performance of the synthetic jet (velocity and momentum output) is limited by the physical limitations of the PZT material. The purpose of this presentation is to provide a high level overview of AFC actuators and applications in an attempt to engage the smart materials community and encourage advanced material development in support of these crucial applications.

Overview of the Micro Vertex Detector for the P bar ANDA experiment

NASA Astrophysics Data System (ADS)

Calvo, Daniela; P¯ANDA MVD Group

2017-02-01

The P bar ANDA experiment is devoted to study interactions between cooled antiproton beams and a fixed target (the interaction rate is of about 107 events/s), hydrogen or heavier nuclei. The innermost tracker of P bar ANDA is the Micro Vertex Detector (MVD), specially designed to ensure the secondary vertex resolution for the discrimination of short-lived charmonium states. Hybrid epitaxial silicon pixels and double-sided silicon microstrips will equip four barrels, arranged around the interaction point, and six forward disks. The experiment features a triggerless architecture with a master clock of 160 MHz, therefore the MVD has to run with a continuous data transmission where the hits need precise timestamps. The energy loss of the particles in the sensor will be measured as well. The challenging request of a triggerless readout suggested to develop custom readout chips for both pixel (ToPix) and microstrip (PASTA) devices. To validate components and the triggerless readout architecture, prototypes have been built and tested. After an overview of the MVD, the technological aspects and performances of some prototypes will be reported.

Science Data Report for the Optical Properties Monitor (OPM) Experiment

NASA Technical Reports Server (NTRS)

Wilkes, Donald R.; Zwiener, James M.

1999-01-01

Long term stability of spacecraft materials when exposed to the space environment continues to be a major area of investigation. The natural and induced environment surrounding a spacecraft can decrease material performance and limit useful lifetimes. The Optical Properties Monitor (OPM) experiment provided the capability to perform the important flight testing of materials and was flown on the Russian Mir Station to study the long term effects of the natural and induced space environment on materials. The core of the OPM in-flight analysis was three independent optical instruments. These instruments included an integrating sphere spectral reflectometer, a vacuum ultraviolet spectrometer, and a Total Integrated Scatter instrument. The OPM also monitored selected components of the environment including molecular contamination. The OPM was exposed on the exterior of the Mir Docking Module for approximately 8-1/2 months. This report describes the OPM experiment, a brief background of its development, program organization, experiment description, mission overview including space environment definition, performance overview, materials data including flight and ground data, in-depth post flight analysis including ground analysis measurements and a summary discussion of the findings and results.

Climate Risk Management and Decision Support Tools for the Agriculture Sector in Lao PDR, Bangladesh, and Indonesia

NASA Astrophysics Data System (ADS)

Allis, E. C.; Greene, A. M.; Cousin, R.

2014-12-01

We describe a comprehensive project for developing climate information and decision support / climate risk management tools in Lao PDR, Bangladesh and Indonesia. Mechanisms are developed for bringing the benefits of these tools to both policy makers and poor rural farmers, with the goal of enabling better management, at the farm level, of the risks associated with climate variability and change. The project comprises several interwoven threads, differentially applied in the different study regions. These include data management and quality control, development of seasonal forecast capabilities, use of dynamic cropping calendars and climate advisories, the development of longer-term climate information for both past and future and a weather index insurance component. Stakeholder engagement and capacity building served as reinforcing and complementary elements to all components. In this talk we will provide a project overview, show how the various components fit together and describe some lessons learned in this attempt to promote the uptake of actionable climate information from farmer to policy level. The applied research project was led by the International Research Institute for Climate and Society (IRI) at Columbia University with funding from the International Fund for Agriculture Development (IFAD) and in close collaboration with our regional partners at the Centre for Climate Risk and Opportunity Management in Southeast Asia Pacific (at Bogor Agricultural University in Indonesia), Indonesia's National Agency for Meteorology, Climatology and Geophysics (BMKG), Lao PDR's National Agriculture and Forestry Research Institute (NAFRI), Laotian Department of Meteorology and Hydrology (DMH), WorldFish Center, Bangladesh Meteorology Department (BMD), and CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS).

An approach for quantitative image quality analysis for CT

NASA Astrophysics Data System (ADS)

Rahimi, Amir; Cochran, Joe; Mooney, Doug; Regensburger, Joe

2016-03-01

An objective and standardized approach to assess image quality of Compute Tomography (CT) systems is required in a wide variety of imaging processes to identify CT systems appropriate for a given application. We present an overview of the framework we have developed to help standardize and to objectively assess CT image quality for different models of CT scanners used for security applications. Within this framework, we have developed methods to quantitatively measure metrics that should correlate with feature identification, detection accuracy and precision, and image registration capabilities of CT machines and to identify strengths and weaknesses in different CT imaging technologies in transportation security. To that end we have designed, developed and constructed phantoms that allow for systematic and repeatable measurements of roughly 88 image quality metrics, representing modulation transfer function, noise equivalent quanta, noise power spectra, slice sensitivity profiles, streak artifacts, CT number uniformity, CT number consistency, object length accuracy, CT number path length consistency, and object registration. Furthermore, we have developed a sophisticated MATLAB based image analysis tool kit to analyze CT generated images of phantoms and report these metrics in a format that is standardized across the considered models of CT scanners, allowing for comparative image quality analysis within a CT model or between different CT models. In addition, we have developed a modified sparse principal component analysis (SPCA) method to generate a modified set of PCA components as compared to the standard principal component analysis (PCA) with sparse loadings in conjunction with Hotelling T2 statistical analysis method to compare, qualify, and detect faults in the tested systems.

AIRMOSS MISSION OVERVIEW

USDA-ARS?s Scientific Manuscript database

Active microwave remote sensing has long been recognized as a key component of an effective environmental observing strategy, due to the strong relationships of radar measurements with geometric and compositional properties of the Earth’s landscape. The Airborne Microwave Observatory of Subcanopy an...

Biosynthesis of Plant and Animal Foods.

ERIC Educational Resources Information Center

Dunne, C. Patrick

1984-01-01

Presents a biochemical overview of the synthesis of food biopolymers that constitute macronutrients in the plant or animal cell. Emphasizes involvement of enzymes in steps characterized by accumulation of materials, activation, polymerization, postpolymerization conversion, and formation of structural components. (JN)

49 CFR 268.1 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... TRANSPORTATION MAGNETIC LEVITATION TRANSPORTATION TECHNOLOGY DEPLOYMENT PROGRAM Overview § 268.1 Definitions. As..., including land, piers, guideways, propulsion equipment and other components attached to guideways, power... described in § 268.3. Maglev means transportation systems employing magnetic levitation that would be...

Industrial power distribution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sorrells, M.A.

This paper is a broad overview of industrial power distribution. Primary focus will be on selection of the various low voltage components to achieve the end product. Emphasis will be on the use of national standards to ensure a safe and well designed installation.

About the U.S. Electricity System and its Impact on the Environment

EPA Pesticide Factsheets

This page provides an overview of the U.S. electric grid, with links to more information about each of the component parts. It also introduces the environmental impacts of electricity generation, delivery, and use.

PubMed Central

AMICIZIA, D.; LAI, P.L.; BRAGAZZI, N.L.; PANATTO, D.

2014-01-01

Summary In the first part of this overview, we described the life cycle of the influenza virus and the pharmacological action of the currently available drugs. This second part provides an overview of the molecular mechanisms and targets of still-experimental drugs for the treatment and management of influenza. Briefly, we can distinguish between compounds with anti-influenza activity that target influenza virus proteins or genes, and molecules that target host components that are essential for viral replication and propagation. These latter compounds have been developed quite recently. Among the first group, we will focus especially on hemagglutinin, M2 channel and neuraminidase inhibitors. The second group of compounds may pave the way for personalized treatment and influenza management. Combination therapies are also discussed. In recent decades, few antiviral molecules against influenza virus infections have been available; this has conditioned their use during human and animal outbreaks. Indeed, during seasonal and pandemic outbreaks, antiviral drugs have usually been administered in mono-therapy and, sometimes, in an uncontrolled manner to farm animals. This has led to the emergence of viral strains displaying resistance, especially to compounds of the amantadane family. For this reason, it is particularly important to develop new antiviral drugs against influenza viruses. Indeed, although vaccination is the most powerful means of mitigating the effects of influenza epidemics, antiviral drugs can be very useful, particularly in delaying the spread of new pandemic viruses, thereby enabling manufacturers to prepare large quantities of pandemic vaccine. In addition, antiviral drugs are particularly valuable in complicated cases of influenza, especially in hospitalized patients. To write this overview, we mined various databases, including Embase, PubChem, DrugBank and Chemical Abstracts Service, and patent repositories. PMID:26137785

Failure Diagnosis and Prognosis of Rolling - Element Bearings using Artificial Neural Networks: A Critical Overview

NASA Astrophysics Data System (ADS)

Rao, B. K. N.; Srinivasa Pai, P.; Nagabhushana, T. N.

2012-05-01

Rolling - Element Bearings are extensively used in almost all global industries. Any critical failures in these vitally important components would not only affect the overall systems performance but also its reliability, safety, availability and cost-effectiveness. Proactive strategies do exist to minimise impending failures in real time and at a minimum cost. Continuous innovative developments are taking place in the field of Artificial Neural Networks (ANNs) technology. Significant research and development are taking place in many universities, private and public organizations and a wealth of published literature is available highlighting the potential benefits of employing ANNs in intelligently monitoring, diagnosing, prognosing and managing rolling-element bearing failures. This paper attempts to critically review the recent trends in this topical area of interest.

Seals/Secondary Fluid Flows Workshop 1997; Volume I

NASA Technical Reports Server (NTRS)

Hendricks, Robert C. (Editor)

2006-01-01

The 1997 Conference provided discussions and data on (a) program overviews, (b) developments in seals and secondary air management systems, (c) interactive seals flows with secondary air or fluid flows and powerstream flows, (d) views of engine externals and limitations, (e) high speed engine research sealing needs and demands, and (f) a short course on engine design development margins. Sealing concepts discussed include, mechanical rim and cavity seals, leaf, finger, air/oil, rope, floating-brush, floating-T-buffer, and brush seals. Engine externals include all components of engine fluid systems, sensors and their support structures that lie within or project through the nacelle. The clean features of the nacelle belie the minefield of challenges and opportunities that lie within. Seals; Secondary air flows; Rotordynamics; Gas turbine; Aircraft; CFD; Testing; Turbomachinery

Sensors, Volume 3, Part II, Chemical and Biochemical Sensors Part II

NASA Astrophysics Data System (ADS)

Göpel, Wolfgang; Jones, T. A.; Kleitz, Michel; Lundström, Ingemar; Seiyama, Tetsuro

1997-06-01

'Sensors' is the first self-contained series to deal with the whole area of sensors. It describes general aspects, technical and physical fundamentals, construction, function, applications and developments of the various types of sensors. This is the second of two volumes focusing on chemical and biochemical sensors. It includes a detailed description of biosensors which often make use of transducer properties of the basic sensors and usually have additional biological components. This volume provides a unique overview of the applications, the possibilities and limitations of sensors in comparison with conventional instrumentation in analytical chemistry. Specific facettes of applications are presented by specialists from different fields including environmental, biotechnological, medical, or chemical process control. This book is an indispensable reference work for both specialits and newcomers, researchers and developers.

Research and technology goals and objectives for Integrated Vehicle Health Management (IVHM)

NASA Technical Reports Server (NTRS)

1992-01-01

Integrated Vehicle Health Management (IVHM) is defined herein as the capability to efficiently perform checkout, testing, and monitoring of space transportation vehicles, subsystems, and components before, during, and after operational This includes the ability to perform timely status determination, diagnostics, and prognostics. IVHM must support fault-tolerant response including system/subsystem reconfiguration to prevent catastrophic failures; and IVHM must support the planning and scheduling of post-operational maintenance. The purpose of this document is to establish the rationale for IVHM and IVHM research and technology planning, and to develop technical goals and objectives. This document is prepared to provide a broad overview of IVHM for technology and advanced development activities and, more specifically, to provide a planning reference from an avionics viewpoint under the OAST Transportation Technology Program Strategic Plan.

Recent Developments of Magnetoresistive Sensors for Industrial Applications

PubMed Central

Jogschies, Lisa; Klaas, Daniel; Kruppe, Rahel; Rittinger, Johannes; Taptimthong, Piriya; Wienecke, Anja; Rissing, Lutz; Wurz, Marc Christopher

2015-01-01

The research and development in the field of magnetoresistive sensors has played an important role in the last few decades. Here, the authors give an introduction to the fundamentals of the anisotropic magnetoresistive (AMR) and the giant magnetoresistive (GMR) effect as well as an overview of various types of sensors in industrial applications. In addition, the authors present their recent work in this field, ranging from sensor systems fabricated on traditional substrate materials like silicon (Si), over new fabrication techniques for magnetoresistive sensors on flexible substrates for special applications, e.g., a flexible write head for component integrated data storage, micro-stamping of sensors on arbitrary surfaces or three dimensional sensing under extreme conditions (restricted mounting space in motor air gap, high temperatures during geothermal drilling). PMID:26569263

Dynamic Impact Testing and Model Development in Support of NASA's Advanced Composites Program

NASA Technical Reports Server (NTRS)

Melis, Matthew E.; Pereira, J. Michael; Goldberg, Robert; Rassaian, Mostafa

2018-01-01

The purpose of this paper is to provide an executive overview of the HEDI effort for NASA's Advanced Composites Program and establish the foundation for the remaining papers to follow in the 2018 SciTech special session NASA ACC High Energy Dynamic Impact. The paper summarizes the work done for the Advanced Composites Program to advance our understanding of the behavior of composite materials during high energy impact events and to advance the ability of analytical tools to provide predictive simulations. The experimental program carried out at GRC is summarized and a status on the current development state for MAT213 will be provided. Future work will be discussed as the HEDI effort transitions from fundamental analysis and testing to investigating sub-component structural concept response to impact events.

The Diesel Exhaust in Miners Study: I. Overview of the Exposure Assessment Process

PubMed Central

Stewart, Patricia A.; Coble, Joseph B.; Vermeulen, Roel; Schleiff, Patricia; Blair, Aaron; Lubin, Jay; Attfield, Michael; Silverman, Debra T.

2010-01-01

This report provides an overview of the exposure assessment process for an epidemiologic study that investigated mortality, with a special focus on lung cancer, associated with diesel exhaust (DE) exposure among miners. Details of several components are provided in four other reports. A major challenge for this study was the development of quantitative estimates of historical exposures to DE. There is no single standard method for assessing the totality of DE, so respirable elemental carbon (REC), a component of DE, was selected as the primary surrogate in this study. Air monitoring surveys at seven of the eight study mining facilities were conducted between 1998 and 2001 and provided reference personal REC exposure levels and measurements for other agents and DE components in the mining environment. (The eighth facility had closed permanently prior to the surveys.) Exposure estimates were developed for mining facility/department/job/year combinations. A hierarchical grouping strategy was developed for assigning exposure levels to underground jobs [based on job titles, on the amount of time spent in various areas of the underground mine, and on similar carbon monoxide (CO, another DE component) concentrations] and to surface jobs (based on the use of, or proximity to, diesel-powered equipment). Time trends in air concentrations for underground jobs were estimated from mining facility-specific prediction models using diesel equipment horsepower, total air flow rates exhausted from the underground mines, and, because there were no historical REC measurements, historical measurements of CO. Exposures to potentially confounding agents, i.e. respirable dust, silica, radon, asbestos, and non-diesel sources of polycyclic aromatic hydrocarbons, also were assessed. Accuracy and reliability of the estimated REC exposures levels were evaluated by comparison with several smaller datasets and by development of alternative time trend models. During 1998–2001, the average measured REC exposure level by facility ranged from 40 to 384 μg m−3 for the underground workers and from 2 to 6 μg m−3 for the surface workers. For one prevalent underground job, ‘miner operator’, the maximum annual REC exposure estimate by facility ranged up to 685% greater than the corresponding 1998–2001 value. A comparison of the historical CO estimates from the time trend models with 1976–1977 CO measurements not used in the modeling found an overall median relative difference of 29%. Other comparisons showed similar levels of agreement. The assessment process indicated large differences in REC exposure levels over time and across the underground operations. Method evaluations indicated that the final estimates were consistent with those from alternative time trend models and demonstrated moderate to high agreement with external data. PMID:20876233

The diesel exhaust in miners study: I. Overview of the exposure assessment process.

PubMed

Stewart, Patricia A; Coble, Joseph B; Vermeulen, Roel; Schleiff, Patricia; Blair, Aaron; Lubin, Jay; Attfield, Michael; Silverman, Debra T

2010-10-01

This report provides an overview of the exposure assessment process for an epidemiologic study that investigated mortality, with a special focus on lung cancer, associated with diesel exhaust (DE) exposure among miners. Details of several components are provided in four other reports. A major challenge for this study was the development of quantitative estimates of historical exposures to DE. There is no single standard method for assessing the totality of DE, so respirable elemental carbon (REC), a component of DE, was selected as the primary surrogate in this study. Air monitoring surveys at seven of the eight study mining facilities were conducted between 1998 and 2001 and provided reference personal REC exposure levels and measurements for other agents and DE components in the mining environment. (The eighth facility had closed permanently prior to the surveys.) Exposure estimates were developed for mining facility/department/job/year combinations. A hierarchical grouping strategy was developed for assigning exposure levels to underground jobs [based on job titles, on the amount of time spent in various areas of the underground mine, and on similar carbon monoxide (CO, another DE component) concentrations] and to surface jobs (based on the use of, or proximity to, diesel-powered equipment). Time trends in air concentrations for underground jobs were estimated from mining facility-specific prediction models using diesel equipment horsepower, total air flow rates exhausted from the underground mines, and, because there were no historical REC measurements, historical measurements of CO. Exposures to potentially confounding agents, i.e. respirable dust, silica, radon, asbestos, and non-diesel sources of polycyclic aromatic hydrocarbons, also were assessed. Accuracy and reliability of the estimated REC exposures levels were evaluated by comparison with several smaller datasets and by development of alternative time trend models. During 1998-2001, the average measured REC exposure level by facility ranged from 40 to 384 μg m⁻³ for the underground workers and from 2 to 6 μg m⁻³ for the surface workers. For one prevalent underground job, 'miner operator', the maximum annual REC exposure estimate by facility ranged up to 685% greater than the corresponding 1998-2001 value. A comparison of the historical CO estimates from the time trend models with 1976-1977 CO measurements not used in the modeling found an overall median relative difference of 29%. Other comparisons showed similar levels of agreement. The assessment process indicated large differences in REC exposure levels over time and across the underground operations. Method evaluations indicated that the final estimates were consistent with those from alternative time trend models and demonstrated moderate to high agreement with external data.

An over-view of robot assisted surgery curricula and the status of their validation.

PubMed

Fisher, Rebecca A; Dasgupta, Prokar; Mottrie, Alex; Volpe, Alessandro; Khan, Mohammed S; Challacombe, Ben; Ahmed, Kamran

2015-01-01

Robotic surgery is a rapidly expanding field. Thus far training for robotic techniques has been unstructured and the requirements are variable across various regions. Several projects are currently underway to develop a robotic surgery curriculum and are in various stages of validation. We aimed to outline the structures of available curricula, their process of development, validation status and current utilization. We undertook a literature review of papers including the MeSH terms "Robotics" and "Education". When we had an overview of curricula in development, we searched recent conference abstracts to gain up to date information. The main curricula are the FRS, the FSRS, the Canadian BSTC and the ERUS initiative. They are in various stages of validation and offer a mixture of theoretical and practical training, using both physical and simulated models. Whilst the FSRS is based on tasks on the RoSS virtual reality simulator, FRS and BSTC are designed for use on simulators and the robot itself. The ERUS curricula benefits from a combination of dry lab, wet lab and virtual reality components, which may allow skills to be more transferable to the OR as tasks are completed in several formats. Finally, the ERUS curricula includes the OR modular training programme as table assistant and console surgeon. Curricula are a crucial step in global standardisation of training and certification of surgeons for robotic surgical procedures. Many curricula are in early stages of development and more work is needed in development and validation of these programmes before training can be standardised. Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Design considerations for fiber composite structures

NASA Technical Reports Server (NTRS)

Chamis, C. C.

1972-01-01

An overview of the design methodology for designing structural components from fiber composites is presented. In particular, the need for new conceptual structural designs for the future is discussed and the evolution of conceptual design is illustrated. Sources of design data, analysis and design procedures, and the basic components of structural fiber composites are cited and described. Examples of tradeoff studies and optimum designs are discussed and a simple structure is described in some detail.

An overview of the artificial intelligence and expert systems component of RICIS

NASA Technical Reports Server (NTRS)

Feagin, Terry

1987-01-01

Artificial Intelligence and Expert Systems are the important component of RICIS (Research Institute and Information Systems) research program. For space applications, a number of problem areas that should be able to make good use of the above tools include: resource allocation and management, control and monitoring, environmental control and life support, power distribution, communications scheduling, orbit and attitude maintenance, redundancy management, intelligent man-machine interfaces and fault detection, isolation and recovery.

Small Explorer Data System MIL-STD-1773 fiber optic bus

NASA Technical Reports Server (NTRS)

Flanegan, Mark; Label, Ken

1992-01-01

The MIL-STD-1773 Fiber Optic Data Bus as implemented in the GSFC Small Explorer Data System (SEDS) for the Small Explorer Program is described. It provides an overview of the SEDS MIL-STD-1773 bus components system design considerations, reliability figures, acceptance and qualification testing requirements, radiation requirements and tests, error handling considerations, and component heritage. The first mission using the bus will be launched in June of 1992.

WFF TOPEX Software Documentation Overview, May 1999. Volume 2

NASA Technical Reports Server (NTRS)

Brooks, Ronald L.; Lee, Jeffrey

2003-01-01

This document provides an overview'of software development activities and the resulting products and procedures developed by the TOPEX Software Development Team (SWDT) at Wallops Flight Facility, in support of the WFF TOPEX Engineering Assessment and Verification efforts.

Definition and testing of the hydrologic component of the pilot land data system

NASA Technical Reports Server (NTRS)

Ragan, Robert M.; Sircar, Jayanta K.

1987-01-01

The specific aim was to develop within the Pilot Land Data System (PLDS) software design environment, an easily implementable and user friendly geometric correction procedure to readily enable the georeferencing of imagery data from the Advanced Very High Resolution Radiometer (AVHRR) onboard the NOAA series spacecraft. A software subsystem was developed within the guidelines set by the PLDS development environment utilizing NASA Goddard Space Flight Center (GSFC) Image Analysis Facility's (IAF's) Land Analysis Software (LAS) coding standards. The IAS current program development environment, the Transportable Applications Executive (TAE), operates under a VAX VMS operating system and was used as the user interface. A brief overview of the ICARUS algorithm that was implemented in the set of functions developed, is provided. The functional specifications decription is provided, and a list of the individual programs and directory names containing the source and executables installed in the IAF system are listed. A user guide is provided for the LAS system documentation format for the three functions developed.

Technical Overview of Ecological Risk Assessment - Analysis Phase: Exposure Characterization

EPA Pesticide Factsheets

Exposure Characterization is the second major component of the analysis phase of a risk assessment. For a pesticide risk assessment, the exposure characterization describes the potential or actual contact of a pesticide with a plant, animal, or media.

Monitored Natural Attenuation Case Study Evaluations

EPA Science Inventory

Monitored natural attenuation (MNA) has been selected as a component of groundwater remedies at several sites with metals and/or radionuclide contamination. An overview of the site characterization effort and remedy performance will be provided for several sites where MNA was se...

How to Purchase, Set Up, & Safeguard a CD-ROM Network.

ERIC Educational Resources Information Center

Almquist, Arne J.

1996-01-01

Presents an overview of the hardware and software required to network CD-ROMs in schools. Topics include network infrastructures, networking software, file server-based systems, CD-ROM servers, vendors of network components, workstations, network utilities, and network management. (LRW)

LIFE CYCLE ASSESSMENT: PRINCIPLES AND PRACTICE

EPA Science Inventory

The following document provides an introductory overview of Life Cycle Assessment (LCA) and describes the general uses and major components of LCA. This document is an update and merger of two previous EPA documents on LCA ("Life Cycle Assessment: Inventory Guidelines and Princip...

Recent Technology Advances in Distributed Engine Control

NASA Technical Reports Server (NTRS)

Culley, Dennis

2017-01-01

This presentation provides an overview of the work performed at NASA Glenn Research Center in distributed engine control technology. This is control system hardware technology that overcomes engine system constraints by modularizing control hardware and integrating the components over communication networks.

VHITAL-160 Thruster Development Status

NASA Technical Reports Server (NTRS)

Sengupta, Anita; Marrese-Reading, Colleen; Hofer, Rich; Owens, Al; Swindlehurst, Ray; Fitzgerald, Dennis

2006-01-01

A general overview on the status of the Very High Isp Thruster with Anode Layer (VHITAL)-160 program is presented. The topics include: 1) Bi TAL Overview; 2) VHITAL Program Overview; 3) Thruster Fabrication; and 4) Thruster Testing.

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol.

PubMed

Morales, Paula; Reggio, Patricia H; Jagerovic, Nadine

2017-01-01

Cannabidiol (CBD) has been traditionally used in Cannabis -based preparation, however historically, it has received far less interest as a single drug than the other components of Cannabis . Currently, CBD generates considerable interest due to its beneficial neuroprotective, antiepileptic, anxiolytic, antipsychotic, and anti-inflammatory properties. Therefore, the CBD scaffold becomes of increasing interest for medicinal chemists. This review provides an overview of the chemical structure of natural and synthetic CBD derivatives including the molecular targets associated with these compounds. A clear identification of their biological targets has been shown to be still very challenging.

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol

PubMed Central

Morales, Paula; Reggio, Patricia H.; Jagerovic, Nadine

2017-01-01

Cannabidiol (CBD) has been traditionally used in Cannabis-based preparation, however historically, it has received far less interest as a single drug than the other components of Cannabis. Currently, CBD generates considerable interest due to its beneficial neuroprotective, antiepileptic, anxiolytic, antipsychotic, and anti-inflammatory properties. Therefore, the CBD scaffold becomes of increasing interest for medicinal chemists. This review provides an overview of the chemical structure of natural and synthetic CBD derivatives including the molecular targets associated with these compounds. A clear identification of their biological targets has been shown to be still very challenging. PMID:28701957

An overview of recent end-to-end wireless medical video telemedicine systems using 3G.

PubMed

Panayides, A; Pattichis, M S; Pattichis, C S; Schizas, C N; Spanias, A; Kyriacou, E

2010-01-01

Advances in video compression, network technologies, and computer technologies have contributed to the rapid growth of mobile health (m-health) systems and services. Wide deployment of such systems and services is expected in the near future, and it's foreseen that they will soon be incorporated in daily clinical practice. This study focuses in describing the basic components of an end-to-end wireless medical video telemedicine system, providing a brief overview of the recent advances in the field, while it also highlights future trends in the design of telemedicine systems that are diagnostically driven.

Dietary fibre: challenges in production and use of food composition data.

PubMed

Westenbrink, Susanne; Brunt, Kommer; van der Kamp, Jan-Willem

2013-10-01

Dietary fibre is a heterogeneous group of components for which several definitions and analytical methods were developed over the past decades, causing confusion among users and producers of dietary fibre data in food composition databases. An overview is given of current definitions and analytical methods. Some of the issues related to maintaining dietary fibre values in food composition databases are discussed. Newly developed AOAC methods (2009.01 or modifications) yield higher dietary fibre values, due to the inclusion of low molecular weight dietary fibre and resistant starch. For food composition databases procedures need to be developed to combine 'classic' and 'new' dietary fibre values since re-analysing all foods on short notice is impossible due to financial restrictions. Standardised value documentation procedures are important to evaluate dietary fibre values from several sources before exchanging and using the data, e.g. for dietary intake research. Copyright © 2012 Elsevier Ltd. All rights reserved.

The Long and Winding Road to Innovation.

PubMed

Beyar, Rafael

2015-07-30

Medicine is developing through biomedical technology and innovations. The goal of any innovation in medicine is to improve patient care. Exponential growth in technology has led to the unprecedented growth of medical technology over the last 50 years. Clinician-scientists need to understand the complexity of the innovation process, from concept to product release, when working to bring new clinical solutions to the bedside. Hence, an overview of the innovation process is provided herein. The process involves an invention designed to solve an unmet need, followed by prototype design and optimization, animal studies, pilot and pivotal studies, and regulatory approval. The post-marketing strategy relative to funding, along with analysis of cost benefit, is a critical component for the adoption of new technologies. Examples of the road to innovation are provided, based on the experience with development of the transcatheter aortic valve. Finally, ideas are presented to contribute to the further development of this worldwide trend in innovation.

Real Talk: Developing a Computer-Delivered Sexual Health Program for Black Men Who Have Sex With Men.

PubMed

Klein, Charles; Lomonaco, Carmela

2016-12-01

HIV disproportionately affects Black men who have sex with men (MSM), yet there are few evidence-based programs that respond to the diverse realities of Black MSM communities. This article examines the development of Real Talk, a new harm reduction-based, sexual health intervention for Black MSM. We first analyze the key themes from our formative research: (1) stigma, discrimination, and intersectionalities in the lives of Black MSM, (2) the importance of safe spaces and community provided by health promotion programs, and (3) moving beyond condoms in sexual health messaging. We then describe our agile design product development process and present an overview of the intervention's components and how they respond to the issues identified in the formative research. In conclusion, we discuss dissemination opportunities and challenges in an age of decreased prevention funding, pre-exposure prophylaxis (PrEP), and the increased use of e-health promotion modalities.

Extracellular matrix and its receptors in Drosophila neural development

PubMed Central

Broadie, Kendal; Baumgartner, Stefan; Prokop, Andreas

2011-01-01

Extracellular matrix (ECM) and matrix receptors are intimately involved in most biological processes. The ECM plays fundamental developmental and physiological roles in health and disease, including processes underlying the development, maintenance and regeneration of the nervous system. To understand the principles of ECM-mediated functions in the nervous system, genetic model organisms like Drosophila provide simple, malleable and powerful experimental platforms. This article provides an overview of ECM proteins and receptors in Drosophila. It then focuses on their roles during three progressive phases of neural development: 1) neural progenitor proliferation, 2) axonal growth and pathfinding and 3) synapse formation and function. Each section highlights known ECM and ECM-receptor components and recent studies done in mutant conditions to reveal their in vivo functions, all illustrating the enormous opportunities provided when merging work on the nervous system with systematic research into ECM-related gene functions. PMID:21688401

Hydrogen Sulfide and Ionic Liquids: Absorption, Separation, and Oxidation.

PubMed

Chiappe, Cinzia; Pomelli, Christian Silvio

2017-06-01

Economical and environmental concerns are the main motivations for development of energy-efficient processes and new eco-friendly materials for the capture of greenhouse gases. Currently, H 2 S capture is dominated by physical and/or chemical absorption technologies, which are, however, energy intensive and often problematic from an environmental point of view due to emission of volatile solvent components. Ionic liquids have been proposed as a promising alternative to conventional solvents because of their low volatility and other interesting properties. The aim of the present review paper is to provide a detailed overview of the achievements and difficulties that have been encountered in finding suitable ionic liquids for H 2 S capture. The effect of ionic liquid anions, cations, and functional groups on the H 2 S absorption, separation, and oxidation are highlighted. Recent developments on yet scarcely available molecular simulations and on the development of robust predictive methods are also discussed.

The Long and Winding Road to Innovation

PubMed Central

Beyar, Rafael

2015-01-01

Medicine is developing through biomedical technology and innovations. The goal of any innovation in medicine is to improve patient care. Exponential growth in technology has led to the unprecedented growth of medical technology over the last 50 years. Clinician-scientists need to understand the complexity of the innovation process, from concept to product release, when working to bring new clinical solutions to the bedside. Hence, an overview of the innovation process is provided herein. The process involves an invention designed to solve an unmet need, followed by prototype design and optimization, animal studies, pilot and pivotal studies, and regulatory approval. The post-marketing strategy relative to funding, along with analysis of cost benefit, is a critical component for the adoption of new technologies. Examples of the road to innovation are provided, based on the experience with development of the transcatheter aortic valve. Finally, ideas are presented to contribute to the further development of this worldwide trend in innovation. PMID:26241234

The teaching portfolio as a professional development tool for anaesthetists.

PubMed

Sidhu, N S

2015-05-01

A teaching portfolio (TP) is a document containing a factual description of a teacher's teaching strengths and accomplishments, allowing clinicians to display them for examination by others. The primary aim of a TP is to improve quality of teaching by providing a structure for self-reflection, which in turn aids professional development in medical education. Contents typically include a personal statement on teaching, an overview of teaching accomplishments and activities, feedback from colleagues and learners, a reflective component and some examples of teaching material. Electronic portfolios are more portable and flexible compared to paper portfolios. Clinicians gain the most benefit from a TP when it is used as a tool for self-reflection of their teaching practice and not merely as a list of activities and achievements. This article explains why and how anaesthetists might use a TP as a tool for professional development in medical education.

Vested Interest theory and disaster preparedness.

PubMed

Miller, Claude H; Adame, Bradley J; Moore, Scott D

2013-01-01

Three studies were designed to extend a combination of vested interest theory (VI) and the extended parallel process model of fear appeals (EPPM) to provide formative research for creating more effective disaster preparedness social action campaigns. The aim was to develop an effective VI scale for assessing individual awareness and 'vestedness' relevant to disaster preparedness. Typical preparedness behaviours are discussed with emphasis on earthquakes and tornados in particular. Brief overviews of VI and the EPPM are offered, and findings are presented from three studies (one dealing with earthquakes, and two with tornados) conducted to determine the factor structure of the key VI components involved, and to develop and test subscales derived from the two theories. The paper finishes with a discussion of future research needs and suggestions on how the new subscales may be applied in the design and execution of more effective disaster preparedness campaigns. © 2013 The Author(s). Journal compilation © Overseas Development Institute, 2013.