Sample records for pajua margus eek
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Spectroscopic study of the Lambda hypernuclei by the (e,e'K +) reaction
DOE Office of Scientific and Technical Information (OSTI.GOV)
Miyoshi, Toshinobu
Hypernuclear spectroscopy study via the (e,e'K +) reaction has been carried out for the first time, establishing a new technique to study Lambda hypernuclei. The high quality electron beam at Jefferson Lab made it possible to measure Lambda hypernuclear spectra with an energy resolution better than 1 MeV (FWHM). The present experiment was designed to make full use of the virtual photon flux, which peaks at very forward angles, by detecting scattered electrons at 0 degrees. Scattered positive kaons were also detected near 0 degrees, where the cross section of the kaon photo-production is maximized. This unique kinematical configuration was realized with the HyperNuclear Spectrometer System (HNSS), which consisted of the Short-Orbit Spectrometer, the Enge Split-Pole Spectrometer, and the splitter magnet. Themore » $$12\\atop{Λ}$$B mass spectrum was measured in the 12C(e,e'K +)$$12\\atop{Λ}$$ reaction with 0.9 MeV (FWHM) energy resolution. The averaged binding energy of the $$12\\atop{Λ}$$B ground state doublet was obtained to be 11.7 ± 0.1 (statistical) ± 0.3 (systematic) MeV, which is consistent with emulsion data. The general spectral structure of the 12C(e,e'K +) $$12\\atop{Λ}$$B reaction was found to be similar to that of the 12C(Λ +,K +)$$12\\atop{Λ}$$C reaction, showing characteristic peaks corresponding to sLambda and pLambda orbits, as well as a few core-excited states. The cross section of the $$12\\atop{Λ}$$B ground state doublet was derived to be 117 ± 13 (statistical) ± 14 (systematic) nb/sr. The theoretical prediction of the cross section was consistent with the present result, validating DWIA calculation for hypernuclear yields. The present study proved the effectiveness of the (e,e'K +) reaction for future Lambda hypernuclear spectroscopy studies.« less
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Gogami, Toshiyuki
In 2009 (August-November), the E05-115 experiment was carried out at JLab to investigate L hypernuclei in the wide mass region up to A = 52 (more » $$7\\atop{Λ}$$He, $$10\\atop{Λ}$$Be, $$12\\atop{Λ}$$B and $$52\\atop{Λ}$$V) with the (e,e'K +) reaction. This is the first attempt to investigate a medium heavy L hypernucleus with the (e,e'K +) reaction. Experimentally, it is difficult to measure heavier L hypernuclei as background rates of particles which originate from electromagnetic processes are roughly in proportion to Z2 (Z: target proton number) in the (e,e'K +) experiment. To perform the experiment, many experimental techniques have been developed and introduced such as optimization of the electron spectrometer configuration (tilt method), clean kaon identification, particle tracking under high multiplicity environment, precise energy scale calibration and so on. In the present thesis, experimental results of the elementary process of p(e,e'K +)L, L hypernuclei of $$7\\atop{Λ}$$He, $$10\\atop{Λ}$$Be, $$12\\atop{Λ}$$B and $$52\\atop{Λ}$$V are shown. Elementary processes of the electroproduction of L and Σ 0, p(e,e'K +)L, Σ 0 were used for the absolute energy scale calibration of our spectrometer systems. A careful Monte Carlo simulation shows that the binding energy can be obtained with a systematic error of 0.11 MeV with our energy scale calibration method. A study of the elementary process of L is important to understand L hypernuclei as it is essential for theoretical calculations of L hypernuclei. The differential cross section of the p(e,e'K +)L reaction at the small K + scattering angle (theta-CM/gamma-K approx. 15.5°), the small Q 2 (approx 0.01 [GeV/c] 2) and the total energy of W = 1.92 GeV, where no experimental data exists was obtained to be 235 ± 13$$+28\\atop{-24}$$ nb/sr. The ground state (1/2 +) binding energy of $$7\\atop{Λ}$$He was already measured in JLab E01-011 (2005). In the present work, the binding energy of 1/2 + state was
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High resolution spectroscopy of the 12Lambda B hypernucleus produced by the (e,e'K+) reaction.
Miyoshi, T; Sarsour, M; Yuan, L; Zhu, X; Ahmidouch, A; Ambrozewicz, P; Androic, D; Angelescu, T; Asaturyan, R; Avery, S; Baker, O K; Bertovic, I; Breuer, H; Carlini, R; Cha, J; Chrien, R; Christy, M; Cole, L; Danagoulian, S; Dehnhard, D; Elaasar, M; Empl, A; Ent, R; Fenker, H; Fujii, Y; Furic, M; Gan, L; Garrow, K; Gasparian, A; Gueye, P; Harvey, M; Hashimoto, O; Hinton, W; Hu, B; Hungerford, E; Jackson, C; Johnston, K; Juengst, H; Keppel, C; Lan, K; Liang, Y; Likhachev, V P; Liu, J H; Mack, D; Margaryan, A; Markowitz, P; Martoff, J; Mkrtchyan, H; Nakamura, S N; Petkovic, T; Reinhold, J; Roche, J; Sato, Y; Sawafta, R; Simicevic, N; Smith, G; Stepanyan, S; Tadevosyan, V; Takahashi, T; Tanida, K; Tang, L; Ukai, M; Uzzle, A; Vulcan, W; Wells, S; Wood, S; Xu, G; Yamaguchi, H; Yan, C
2003-06-13
High-energy, cw electron beams at new accelerator facilities allow electromagnetic production and precision study of hypernuclear structure, and we report here on the first experiment demonstrating the potential of the (e,e'K+) reaction for hypernuclear spectroscopy. This experiment is also the first to take advantage of the enhanced virtual photon flux available when electrons are scattered at approximately zero degrees. The observed energy resolution was found to be approximately 900 keV for the (12)(Lambda)B spectrum, and is substantially better than any previous hypernuclear experiment using magnetic spectrometers. The positions of the major excitations are found to be in agreement with a theoretical prediction and with a previous binding energy measurement, but additional structure is also observed in the core excited region, underlining the future promise of this technique.
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Spectroscopic Investigation of p-Shell Lambda Hypernuclei by the (e,e'K +) Reaction
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, Chunhua
2014-08-01
Hypernuclear spectroscopy is a powerful tool to investigate Lambda-N interaction. Compared with other Lambda hypernuclei productions, electroproduction via the (e,e'K+) reaction has the advantage of exciting states deeply inside of the hypernucleus and achieving sub-MeV energy resolution. The E05-115 experiment, which was successfully performed in 2009, is the third generation hypernuclear experiment in JLab Hall C. A new splitter magnet and electron spectrometer were installed, and beam energy of 2.344 GeV was selected in this experiment. These new features gave better field uniformity, optics quality and made the tilt method more effective in improving yield-to-background ratio. The magnetic optics ofmore » the spectrometers were carefully studied with GEANT simulation, and corrections were applied to compensate for the fringe field cross talk between the compact spectrometer magnets. The non-linear least chi-squared method was used to further calibrate the spectrometer with the events from Lambda, Sigma0 and B12Lambda and uniform magnetic optics as well as precise kinematics were achieved. Several p-shell Lambda hypernuclear spectra, including B 12 Λ, Be 10 Λ, He 7 Λ, were obtained with high energy resolution and good accuracy. For B 12 Λ, eight peaks were recognized with the resolution of ~540keV (FWHM), and the ground state binding energy was obtained as 11.529 ± 0.012(stat.) ± 0.110(syst.) MeV. Be 10 Λ, twelve peaks were recognized with the resolution of ~520keV (FWHM), and the binding energy of the ground state was determined as 8.710 ± 0.059(stat.) ± 0.114(syst.) MeV. For He 7 Λ, three peaks were recognized with the resolution of ~730keV, and the ground state binding energy was obtained as 5.510 ± 0.050(stat.) ± 0.120(syst.) MeV. Compared with the published data of B 12 Λ from the JLab Hall A experiment, four extra peaks were fitted and interpreted thanks to the highest ever energy resolution and sufficient statistics. The determined binding
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... Staying Safe Videos for Educators Search English Español Eczema KidsHealth / For Kids / Eczema What's in this article? ... need to worry. It's just eczema. What Is Eczema? Eczema (say: EK-zeh-ma) is also called ...
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ERIC Educational Resources Information Center
St. Julien, Laurie
2010-01-01
Students from thirteen fifth-grade classrooms from six different elementary schools investigate the preferred escape routes of cockroaches. These identified routes of 90-, 120-, 150-, and 180-degrees are the research findings of Paolo Dominici, an Italian scientist. The students used rubber cockroaches and lizards to map out these escape routes.…
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Many-Body Effects on Optical Carrier Cooling in Intrinsic Semiconductors at Low Lattice Temperatures
2008-07-11
Fg, 78.40.Fy, 78.55.Cr I . INTRODUCTION It is well known that the optical properties of an atomic vapor are essentially determined by the properties...equal temperatures in the papers by Rupper et al.12 and by Sheik- Bahae et al.13 for both carriers and phonons cannot be applied to quasiequilibrium...2 + i 0 − 2e2 2 0 b 0 dk k2 rvck 21 − fek − fhk Eek + Ehk + i 02 − Eek + Ehk2 , 4 where 0 is the homogeneous
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Superfund Record of Decision: National Starch & Chemical ...
... wlwr'c: III = hazan' illtlt'x. lIu!w = 1:~;tim..II'd wor.!;t CiI!;e illl ... s. Shon-term Effectiveness refers to the tec.h1uQ1 and ... It ru~sd~~~ l~~~ .: G!""ar:ts C=eek. ...
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NASA Astrophysics Data System (ADS)
Tang, L.; Chen, C.; Gogami, T.; Kawama, D.; Han, Y.; Yuan, L.; Matsumura, A.; Okayasu, Y.; Seva, T.; Rodriguez, V. M.; Baturin, P.; Acha, A.; Achenbach, P.; Ahmidouch, A.; Albayrak, I.; Androic, D.; Asaturyan, A.; Asaturyan, R.; Ates, O.; Badui, R.; Baker, O. K.; Benmokhtar, F.; Boeglin, W.; Bono, J.; Bosted, P.; Brash, E.; Carter, P.; Carlini, R.; Chiba, A.; Christy, M. E.; Cole, L.; Dalton, M. M.; Danagoulian, S.; Daniel, A.; De Leo, R.; Dharmawardane, V.; Doi, D.; Egiyan, K.; Elaasar, M.; Ent, R.; Fenker, H.; Fujii, Y.; Furic, M.; Gabrielyan, M.; Gan, L.; Garibaldi, F.; Gaskell, D.; Gasparian, A.; Gibson, E. F.; Gueye, P.; Hashimoto, O.; Honda, D.; Horn, T.; Hu, B.; Hungerford, Ed V.; Jayalath, C.; Jones, M.; Johnston, K.; Kalantarians, N.; Kanda, H.; Kaneta, M.; Kato, F.; Kato, S.; Kawai, M.; Keppel, C.; Khanal, H.; Kohl, M.; Kramer, L.; Lan, K. J.; Li, Y.; Liyanage, A.; Luo, W.; Mack, D.; Maeda, K.; Malace, S.; Margaryan, A.; Marikyan, G.; Markowitz, P.; Maruta, T.; Maruyama, N.; Maxwell, V.; Millener, D. J.; Miyoshi, T.; Mkrtchyan, A.; Mkrtchyan, H.; Motoba, T.; Nagao, S.; Nakamura, S. N.; Narayan, A.; Neville, C.; Niculescu, G.; Niculescu, M. I.; Nunez, A.; Nuruzzaman, Nomura, H.; Nonaka, K.; Ohtani, A.; Oyamada, M.; Perez, N.; Petkovic, T.; Pochodzalla, J.; Qiu, X.; Randeniya, S.; Raue, B.; Reinhold, J.; Rivera, R.; Roche, J.; Samanta, C.; Sato, Y.; Sawatzky, B.; Segbefia, E. K.; Schott, D.; Shichijo, A.; Simicevic, N.; Smith, G.; Song, Y.; Sumihama, M.; Tadevosyan, V.; Takahashi, T.; Taniya, N.; Tsukada, K.; Tvaskis, V.; Veilleux, M.; Vulcan, W.; Wells, S.; Wesselmann, F. R.; Wood, S. A.; Yamamoto, T.; Yan, C.; Ye, Z.; Yokota, K.; Zhamkochyan, S.; Zhu, L.; HKS JLab E05-115; E01-011 Collaborations
2014-09-01
Since the pioneering experiment E89-009 studying hypernuclear spectroscopy using the (e,e'K+) reaction was completed, two additional experiments, E01-011 and E05-115, were performed at Jefferson Lab. These later experiments used a modified experimental design, the "tilt method," to dramatically suppress the large electromagnetic background, and allowed for a substantial increase in luminosity. Additionally, a new kaon spectrometer, HKS (E01-011), a new electron spectrometer, HES, and a new splitting magnet (E05-115) were added to produce new data sets of precision, high-resolution hypernuclear spectroscopy. All three experiments obtained a spectrum for Λ12B, which is the most characteristic p-shell hypernucleus and is commonly used for calibration. Independent analyses of these different experiments demonstrate excellent consistency and provide the clearest level structure to date of this hypernucleus as produced by the (e,e'K+) reaction. This paper presents details of these experiments, and the extraction and analysis of the observed Λ12B spectrum.
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Optical Emissions of Sprite Streamers in Weak Electric Fields
NASA Astrophysics Data System (ADS)
Liu, N.; Pasko, V. P.
2004-12-01
Sprites commonly consist of large numbers of needle-shaped filaments of ionization [e.g., Gerken and Inan, JASTP, 65, 567, 2003] and typically initiate at altitudes 70-75 km in a form of upward and downward propagating streamers [Stanley et al., GRL, 26, 3201, 1999; Stenbaek-Nielsen et al., GRL, 27, 3829, 2000; McHarg et al., JGR, 107, 1364, 2002; Moudry et al., JASTP, 65, 509, 2003]. The strong electric fields E exceeding the conventional breakdown threshold field Ek are needed for initiation of sprite streamers from single electron avalanches and recent modeling studies indicate that streamers propagating in fields E>Ek experience strong acceleration and expansion in good agreement with the above cited observations [Liu and Pasko, JGR, 109, A04301, 2004]. The initiated streamers are capable of propagating in fields substantially lower than Ek [Allen and Ghaffar, J. Phys. D: Appl. Phys., 28, 331, 1995] and it is expected that a significant part of sprite optical output comes from regions with E
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Women in the Army Policy Review
1982-11-12
chondromalacia of the perfornmance-limiting conditions thait *eiulted from an 8-1%eek patella (21). hip or neck of femur stress fracture (20). sprains...by the Chondromalacia of patella 21 10 Hip or neck or femur stress fracture 20 9 apparent lack of heel stability inherent in ;he Army boot used Ankle
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1983-03-01
acoustic wave pattern and, if so, word recognitios would be a sliple matter of the voice recogniticn system scanning the pattern, comparing the slmple...TRAINING WEEL - EEK#1 ORD# UTTERANCE CRT PRCtMPT (co0THREE THREE (Oe1EUROPE ERP V)r;_ OVE IT LEFT MCV7 IT LEFT 01 !CARRIAGE RETURN CAER RETURN LOGOLT LOGO UT
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Greek-Turkish Crises since 1955. Implications for Greek-Turkish Conflict Management
1997-03-01
NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS GREEK-TURKISH CRISES SINCE 1955. IMPLICATIONS FOR GREEK-TURKISH CONFLICT MANAGEMENT by...EU, WEU) have only to gain from a Greek-Turkish rapprochement. 14. SUBJECT TERMS GrEek-Turkish RElATiONS, CRiSiS MANAgEMENT, CONfLICT management 15...crises, because the intended outcome of mediation attempts has been regional stability instead of Greek-Turkish conflict management . Power mediation
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Proceedings of 1981 Western Region Technical Symposium on Electronic Warfare
1981-01-01
LS"............. ...... ... 219 "S EEK TALK - A J AM -R ES ISTANT TACT!CA i. CO MMrVL’N ICATION 1 ý’Y 3TI VS ..T ....".. ......... ...... 33...commands, and other Department and Gray data base development, and computer of Defense agencies by providing EW combat modelling. analysis support to...inter- base radios and and Coirqunications Countermeasures surface-to-air missile communications (CCM) were exercised together for the nets. Two
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Tang, Hsin-Chieh; Chang, Pei-Chun; Chen, Yu-Chian
2016-01-01
Decreasing iron uptake and increasing iron efflux may result in cell death by oxidative inactivation of vital enzymes. Applying the dual function of neutrophil gelatinase-associated lipocalin (NGAL) could achieve the goal of iron depletion in the cancer cells. Tyr106, Lys125 or Lys134 was the key binding site for NGAL protein to sequester iron-chelating siderophores. In this study, we employed all bioactive peptides in peptide databank to dock with the siderophore-binding sites of NGAL protein by virtual screening. In addition, we performed molecular dynamics (MD) simulation to observe the molecular character and structural variation of ligand-protein interaction. Glu-Glu-Lys-Glu (EEKE), Glu-Glu-Asp-Cys-Lys (EEDCK), and Gly-Glu-Glu-Cys-Asp (GEECD) were selected preliminarily by rigorous scoring functions for further investigation. GEECD was excluded due to higher binding total energy than the others. Moreover, we also excluded EEKE due to larger influence to the stability of binding residues by the information of root mean square fluctuation (RMSF) and principal component analysis (PCA). Thus, we suggested that EEDCK was the potential bioactive peptide which had been proved to inhibit malignant cells for targeted cancer therapy. Graphical Abstract Perspective drug design of occupying the siderophore-binding sites of NGAL outside the cell temporarily by a potential short peptide until NGAL enters into the cell, and releasing the siderophore-binding sites inside the cell.
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Hypernuclear Spectroscopy at JLab Hall C
NASA Astrophysics Data System (ADS)
Hashimoto, O.; Chiba, A.; Doi, D.; Fujii, Y.; Gogami, T.; Kanda, H.; Kaneta, M.; Kawama, D.; Maeda, K.; Maruta, T.; Matsumura, A.; Nagao, S.; Nakamura, S. N.; Shichijo, A.; Tamura, H.; Taniya, N.; Yamamoto, T.; Yokota, K.; Kato, S.; Sato, Y.; Takahashi, T.; Noumi, H.; Motoba, T.; Hiyama, E.; Albayrak, I.; Ates, O.; Chen, C.; Christy, M.; Keppel, C.; Kohl, M.; Li, Y.; Liyanage, A.; Tang, L.; Walton, T.; Ye, Z.; Yuan, L.; Zhu, L.; Baturin, P.; Boeglin, W.; Dhamija, S.; Markowitz, P.; Raue, B.; Reinhold, J.; Hungerford, Ed. V.; Ent, R.; Fenker, H.; Gaskell, D.; Horn, T.; Jones, M.; Smith, G.; Vulcan, W.; Wood, S. A.; Johnston, C.; Simicevic, N.; Wells, S.; Samanta, C.; Hu, B.; Shen, J.; Wang, W.; Zhang, X.; Zhang, Y.; Feng, J.; Fu, Y.; Zhou, J.; Zhou, S.; Jiang, Y.; Lu, H.; Yan, X.; Ye, Y.; Gan, L.; Ahmidouch, A.; Danagoulian, S.; Gasparian, A.; Elaasar, M.; Wesselmann, F. R.; Asaturyan, A.; Margaryan, A.; Mkrtchyan, A.; Mkrtchyan, H.; Tadevosyan, V.; Androic, D.; Furic, M.; Petkovic, T.; Seva, T.; Niculescu, G.; Niculescu, I.; Rodriguez, V. M.; Cisbani, E.; Cusanno, F.; Garibaldi, F.; Uuciuoli, G. M.; De Leo, R.; Maronne, S.; Achenback, P.; Pochodzala, J.
2010-04-01
Since the 1st generation experiment, E89-009, which was successfully carried out as a pilot experiment of (e,e'K+) hypernuclear spectroscopy at JLab Hall C in 2000, precision hypernuclear spectroscopy by the (e,e'K+) reactions made considerable progress. It has evolved to the 2nd generation experiment, E01-011, in which a newly constructed high resolution kaon spectrometer (HKS) was installed and the "Tilt method" was adopted in order to suppress large electromagnetic background and to run with high luminosity. Preliminary high-resolution spectra of 7ΛHe and 28ΛAl together with that of 12ΛB that achieved resolution better than 500 keV(FWHM) were obtained. The third generation experiment, E05-115, has completed data taking with an experimental setup combining a new splitter magnet, high resolution electron spectrometer (HES) and the HKS used in the 2nd generation experiment. The data were accumulated with targets of 7Li, 9Be, 10B, 12C and 52Cr as well as with those of CH 2 and H 2O for calibration. The analysis is under way with particular emphasis of determining precision absolute hypernuclear masses. In this article, hypernuclear spectroscopy program in the wide mass range at JLab Hall C that has undergone three generation is described.
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The Effect of Moisture on Carbon Fiber Reinforced Epoxy Composites. 1. Diffusion
1976-09-27
II i NSWC/WOL/’r 76-7 0 00 WHITE OAK LABORATORY THE EFFECT OF MOISTURE ON CARBON FIBER REINFORCED EPOXY COMPOSITES I DIFFUSION 0 BY Joseph M. AugI 27...Effect of Moisture on Carbon Fiber’ Reinorcd EoxyComposites. onZI j , l Joseph M./Augll - lan E./egr ,. E RORMING ORGANIZATION NAME AND ADDRESS 10...Diffusion Carbon fiber composite* 20. A bf AACT (Ceedhlua on rverse side it meosemp &W idmtl’ 5 bl eek mmbeet) Mathematical models are suggested for
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-28
..., Inc., Los Feliz Car Wash, Margus Auto Electric Exchange, Inc., Midway Drilling & Pump Company, MK...: American Marble & Onyx Company, Inc., Arroyo Car Wash Corporation, Bay Cities Container Corporation, Brett... Corporation, George J. Peckham, Jr., H.W. Hull & Sons, Inc., Hacienda Car Wash, Inc., Hiro's Transmission, Inc...
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Estimating the ROI on an ERP for Naval Aviation Operations Using Market Comparables
2006-09-01
ed . Harper Business, New York, NY (1993), last accessed January 2006. Housel, T., and Bell, A.H., Measuring and Managing Knowledge, McGraw - Hill ...1 T. Housel and A.H. Bell. Measuring and Managing Knowledge, McGraw - Hill Irwin, 2001, p. 91. 2 received and de-conflicted...eek s) o ut o f th is 8 we ek LT are us ed to l ear n h ow to exa min e, r evi ew an d c ritiq ue the da ily sch edu le Th ere
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A Game-Theoretic Measure of Presence for Assessing Aircraft Carrier Options.
1982-10-01
AD-A121 599 A GAME -THEORETIC MEASURE 0F PRESENCE FOR ASSESSIN NO ANALYSES ALEXANDRIA VA PROGRAM ANALYR PRE P S IE O ESE UNCLASSIFED JH GPOTTE ET...1. REPORT MNUM 1 L GOVT ACCESRIM IM. REINT5 CPAALOG NUOGG 14. TITLE Cid ubMsj S. TYPE OF REPORT & PERIOD COVERED A Game -Theoretic Measure of...NOTES C Is. KEY wOrS (0mM. 0a No" f .a..eaup meM RSEI’ p eek ... l6t Game theory, Zero-sum games , Col Blotto games , aircraft carriers, alternative
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Spectroscopic Research of Lambda Hypdernuclei at JLab Hall C
NASA Astrophysics Data System (ADS)
Gogami, T.; Achenbach, P.; Ahmidouch, A.; Albayrak, I.; Androic, D.; Asaturyan, A.; Asaturyan, R.; Ates, O.; Baturin, P.; Badui, R.; Boeglin, W.; Bono, J.; Brash, E.; Carter, P.; Chen, C.; Chiba, A.; Christy, E.; Dalton, M.; Danagoulian, S.; De Leo, R.; Doi, D.; Elaasar, M.; Ent, R.; Fujii, Y.; Furic, M.; Gabrielyan, M.; Gan, L.; Garibaldi, F.; Gaskell, D.; Gasparian, A.; Hashimoto, O.; Horn, T.; Hu, B.; Hungerford, Ed. V.; Jones, M.; Kanda, H.; Kaneta, M.; Kato, S.; Kawai, M.; Kawama, D.; Khanal, H.; Kohl, M.; Liyanage, A.; Luo, W.; Maeda, K.; Margaryan, A.; Markowitz, P.; Maruta, T.; Matsumura, A.; Maxwell, V.; Mkrtchyan, A.; Mkrtchyan, H.; Nagao, S.; Nakamura, S. N.; Narayan, A.; Neville, C.; Niculescu, G.; Niculescu, M. I.; Nunez, A.; Nuruzzaman; Okayasu, Y.; Petkovic, T.; Pochodzalla, J.; Qiu, X.; Reinhold, J.; Rodriguez, V. M.; Samanta, C.; Sawatzky, B.; Seva, T.; Shichijo, A.; Tadevosyan, V.; Tang, L.; Taniya, N.; Tsukada, K.; Veilleux, M.; Vulcan, W.; Wesselmann, F. R.; Wood, S. A.; Yamamoto, T.; Ya, L.; Ye, Z.; Yokota, K.; Yuan, L.; Zhamkochyan, S.; Zhu, L.
A Λ hyperon which has a strangeness can be bound in deep inside of a nucleus since a Λ does not suffer from the Pauli exclusion principle from nucleons. Thus, a Λ could be a useful tool to investigate inside of a nucleus. Since 2000, Λ hypernuclear spectroscopic experiments by the (e,e'k) reaction have been performed at the experimental hall C in Thomas Jefferson National Accelerator Facility (JLab Hall C). An experiment, JLab E05-115 was carried out to investigate Λ hypernuclei with a wide mass range (the mass number, A = 7, 9, 10, 12, 52). The latest analysis status of JLab E05-115 experiment is discussed in the present article.
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Spectroscopic Research of Lambda Hypdernuclei at JLab Hall C
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gogami, Toshiyuki; et. al.,
2014-03-01
A Lambda hyperon which has a strangeness can be bound in deep inside of a nucleus since a Λ does not suffer from the Pauli exclusion principle from nucleons. Thus, a Λ could be a useful tool to investigate inside of a nucleus. Since 2000, Lambda hypernuclear spectroscopic experiments by the (e,e'k) reaction have been performed at the experimental hall C in Thomas Jefferson National Accelerator Facility (JLab Hall C). An experiment, JLab E05-115 was carried out to investigate Lambda hypernuclei with a wide mass range (the mass number, A = 7, 9, 10, 12, 52). The latest analysis statusmore » of JLab E05-115 experiment is discussed in the present article.« less
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A uniquely adaptable pore is consistent with NALCN being an ion sensor
Senatore, Adriano; Spafford, J. David
2013-01-01
NALCN is an intriguing, orphan ion channel among the 4x6TM family of related voltage-gated cation channels, sharing a common architecture of four homologous domains consisting of six transmembrane helices, separated by three cytoplasmic linkers and delimited by N and C-terminal ends. NALCN is one of the shortest 4x6TM family members, lacking much of the variation that provides the diverse palate of gating features, and tissue specific adaptations of sodium and calcium channels. NALCN’s most distinctive feature is that that it possesses a highly adaptable pore with a calcium-like EEEE selectivity filter in radially symmetrical animals and a more sodium-like EEKE or EKEE selectivity filter in bilaterally symmetrical animals including vertebrates. Two lineages of animals evolved alternative calcium-like EEEE and sodium-like EEKE / EKEE pores, spliced to regulate NALCN functions in differing cellular environments, such as muscle (heart and skeletal) and secretory tissue (brain and glands), respectively. A highly adaptable pore in an otherwise conserved ion channel in the 4x6TM channel family is not consistent with a role for NALCN in directly gating a significant ion conductance that can be either sodium ions or calcium ions. NALCN was proposed to be an expressible Gd3+-sensitive, NMDG+-impermeant, non-selective and ohmic leak conductance in HEK-293T cells, but we were unable to distinguish these reported currents from leaky patch currents (ILP) in control HEK-293T cells. We suggest that NALCN functions as a sensor for the much larger UNC80/UNC79 complex, in a manner consistent with the coupling mechanism known for other weakly or non-conducting 4x6TM channel sensor proteins such as Nax or Cav1.1. We propose that NALCN serves as a variable sensor that responds to calcium or sodium ion flux, depending on whether the total cellular current density is generated more from calcium-selective or sodium-selective channels. PMID:23442378
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A uniquely adaptable pore is consistent with NALCN being an ion sensor.
Senatore, Adriano; Spafford, J David
2013-01-01
NALCN is an intriguing, orphan ion channel among the 4x6TM family of related voltage-gated cation channels, sharing a common architecture of four homologous domains consisting of six transmembrane helices, separated by three cytoplasmic linkers and delimited by N and C-terminal ends. NALCN is one of the shortest 4x6TM family members, lacking much of the variation that provides the diverse palate of gating features, and tissue specific adaptations of sodium and calcium channels. NALCN's most distinctive feature is that that it possesses a highly adaptable pore with a calcium-like EEEE selectivity filter in radially symmetrical animals and a more sodium-like EEKE or EKEE selectivity filter in bilaterally symmetrical animals including vertebrates. Two lineages of animals evolved alternative calcium-like EEEE and sodium-like EEKE / EKEE pores, spliced to regulate NALCN functions in differing cellular environments, such as muscle (heart and skeletal) and secretory tissue (brain and glands), respectively. A highly adaptable pore in an otherwise conserved ion channel in the 4x6TM channel family is not consistent with a role for NALCN in directly gating a significant ion conductance that can be either sodium ions or calcium ions. NALCN was proposed to be an expressible Gd ( 3+) -sensitive, NMDG (+) -impermeant, non-selective and ohmic leak conductance in HEK-293T cells, but we were unable to distinguish these reported currents from leaky patch currents (ILP) in control HEK-293T cells. We suggest that NALCN functions as a sensor for the much larger UNC80/UNC79 complex, in a manner consistent with the coupling mechanism known for other weakly or non-conducting 4x6TM channel sensor proteins such as Nax or Cav 1.1. We propose that NALCN serves as a variable sensor that responds to calcium or sodium ion flux, depending on whether the total cellular current density is generated more from calcium-selective or sodium-selective channels.
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Bank-to-Turn Cruise Missile Terminal Guidance and Control Law Comparison.
1983-06-01
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Hypernuclear Spectroscopy with Electron Beam at JLab Hall C
NASA Astrophysics Data System (ADS)
Fujii, Y.; Chiba, A.; Doi, D.; Gogami, T.; Hashimoto, O.; Kanda, H.; Kaneta, M.; Kawama, D.; Maeda, K.; Maruta, T.; Matsumura, A.; Nagao, S.; Nakamura, S. N.; Shichijo, A.; Tamura, H.; Taniya, N.; Yamamoto, T.; Yokota, K.; Kato, S.; Sato, Y.; Takahashi, T.; Noumi, H.; Motoba, T.; Hiyama, E.; Albayrak, I.; Ates, O.; Chen, C.; Christy, M.; Keppel, C.; Kohl, M.; Li, Y.; Liyanage, A.; Tang, L.; Walton, T.; Ye, Z.; Yuan, L.; Zhu, L.; Baturin, P.; Boeglin, W.; Dhamija, S.; Markowitz, P.; Raue, B.; Reinhold, J.; Hungerford, Ed. V.; Ent, R.; Fenker, H.; Gaskell, D.; Horn, T.; Jones, M.; Smith, G.; Vulcan, W.; Wood, S. A.; Johnston, C.; Simicevic, N.; Wells, S.; Samanta, C.; Hu, B.; Shen, J.; Wang, W.; Zhang, X.; Zhang, Y.; Feng, J.; Fu, Y.; Zhou, J.; Zhou, S.; Jiang, Y.; Lu, H.; Yan, X.; Ye, Y.; Gan, L.; Ahmidouch, A.; Danagoulian, S.; Gasparian, A.; Elaasar, M.; Wesselmann, F. R.; Asaturyan, A.; Margaryan, A.; Mkrtchyan, A.; Mkrtchyan, H.; Tadevosyan, V.; Androic, D.; Furic, M.; Petkovic, T.; Seva, T.; Niculescu, G.; Niculescu, I.; López, V. M. Rodríguez; Cisbani, E.; Cusanno, F.; Garibaldi, F.; Uuciuoli, G. M.; de Leo, R.; Maronne, S.
2010-10-01
Hypernuclear spectroscopy with electron beam at JLab Hall C has been studied since 2000. The first experiment, JLab E89-009, demonstrated the possibility of the (e,e'K+) reaction for hypernuclear spectroscopy by achieving an energy resolution of better than 1 MeV (FWHM). The second experiment, JLab E01-011 employed a newly constructed high resolution kaon spectrometer and introduced a vertically tilted electron arm setup to avoid electrons from bremsstrahlung and Moeller scattering. The setup allowed us to have 10 times yield rate and 4 times better signal to accidental ratio with expected energy resolution of 400 keV (FWHM). The third experiment, JLab E05-11B will be performed in 2009 with employing newly constructed high resolution electron spectrometer and a new charge-separation magnet. With the fully customized third generation experimental setup, we can study a variety of targets up to medium-heavy ones such as 52Cr.
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Merolli, Antonio; Rocchi, Lorenzo; De Spirito, Marco; Federico, Francesco; Morini, Alessandro; Mingarelli, Luigi; Fanfani, Francesco
2016-03-01
Application of carbon-fiber-reinforced-polymer (CFRP) artifacts in humans has been promoted in Orthopedic and Trauma Surgery. Literature documents the biocompatibility of materials used, namely carbon fibers (CF) and poly-ether thermoplastics, like poly-ether-ether-ketone (PEEK). A properly designed and accurately implanted composite artifact should not expose its fibers during or after surgery: however this may happen. A white Caucasian woman came to our attention 11 months after surgery for a wrist fracture. She had a severe impairment, being unable to flex the thumb; index finger and distal phalanx of third finger. We retrieved a correctly positioned plate and documented an aggressive erosive flexor tendons synovitis with eroded stumps of flexor tendons. The plate and soft tissues were analyzed by Visible Light and Scanning Electron Microscopy. Histopathology showed granulomatous fibrogenic process with CF engulfed inside multinucleated giant cells. Fibers were unmasked and disrupted inside the holes where screws were tightened and corrugation of the polymer coating led to further unmasking. The mechanism of foreign-body reaction to CF has not been studied in depth yet, particularly at the ultrastructural level and in Humans. This case documents a damage occurred in a clinical application and which was theoretically possible. Our opinion is that a proper way to promote the use of CRFP in the Clinic in the short term is to direct Research towards finding a better way to prevent CF debris to be exposed and released. In the longer term, the biological response to CF deserves a deeper understanding.
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[Operative differential therapy of rheumatic wrists].
Dinges, H; Fürst, M; Rüther, H; Schill, S
2007-09-01
The wrists are affected in the long-term in 90% of people with rheumatism and are often (42%) the first manifestation of a destructive disease. The functionality of the wrist and the whole hand is of great importance because in many cases loss of function of the wrists leads to severe limitations. Local and operative treatment of the wrist in rheumatoid arthritis (RA) is one of the main duties in rheuma-orthopaedics. For operative treatment there is a finely tuned differential therapeutic spectrum available. The diagnostic indications take the local and total pattern of affection, the current systemic therapy as well as patient wishes and patient compliance into consideration. In the early stages according to LDE (Larsen, Dale, Eek), soft tissues operations such as articulo-tenosynovectomy (ATS) are most commonly carried out. In further advanced stages osseus stabilisation must often be performed. At this point a smooth transition from partial arthrodesis to complete fixation is possible. After initial euphoria, arthroplasty of the wrist is being increasingly less used for operative treatment due to the unconvincing long-term results and high complication rate. With reference to the good long-term results of all operative procedures, in particular early ATS with respect to pain, function and protection of tendons, after failure of medicinal treatment and persistence of inflammatory activity in the wrist, patients should be transferred to an experienced rheuma-orthopaedic surgeon.
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Atomic Data and Spectral Line Intensities for NI XVII
NASA Technical Reports Server (NTRS)
Bhatia, A. K.; Landi, E.
2011-01-01
Electron impact collision strengths, energy levels, oscillator strengths, and spontaneous radiative decay rates are calculated for Ni XVII. We include in the calculations the 23 lowest configurations, corresponding to 159 fine-structure levels: 3l3l', 3l4l0'' , and 3s5l0''' , with l,l' = s,p,d, l'' = s,p,d, f, and l''' = s,p,d. Collision strengths are calculated at five incident energies for all transitions at varying energies above the threshold of each transition. One additional energy, very close to the threshold of each transition, has also been included. Calculations have been carried out using the Flexible Atomic Code in the distorted wave approximation. Additional calculations have been performed with the University College London suite of codes for comparison. Excitation rate coefficients are calculated as a function of electron temperature by assuming a Maxwellian electron velocity distribution. Using the excitation rate coefficients and the radiative transition rates of the present work, statistical equilibrium equations for level populations are solved at electron densities covering the range of 10(exp 8) - 10(exp 14) / cubic cm and at an electron temperature of logT(sub e)e(K) = 6.5, corresponding to the maximum abundance of Ni XVII. Spectral line intensities are calculated, and their diagnostic relevance is discussed. This dataset will be made available in the next version of the CHIANTI database
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Edwards, Nicola C; Steeds, Richard P; Chue, Colin D; Stewart, Paul M; Ferro, Charles J; Townend, Jonathan N
2012-01-01
AIM Mineralocorticoid receptor blockade (MRBs) in combination with angiotensin converting enzyme (ACE) inhibitors and angiotensin-II receptor blockade (ARBs) improve prognostic markers of cardiovascular and renal disease in early stage chronic kidney disease (CKD). Concerns relating to the safety and tolerability of MRBs in CKD may limit their use in a non clinical trial setting. METHODS In the Chronic Renal Impairment in Birmingham II study, 115 patients with non-diabetic early stage CKD (eGFR 30–89 ml/min/1.73m2) received 25 mg daily of spironolactone for 4 weeks before randomization to continuing treatment or placebo for a further 36 weeks. All patients were on ACE inhibitors and/or ARB therapy. Potassium and renal function were checked at weeks 1, 2, 4, 8, 16, 28 and 40. The incidence of hyperkalaemia, significant renal dysfunction (reduction eGFR ≥25%) and adverse effects was assessed. RESULTS After 40 weeks of treatment the incidence of serious hyperkalaemia (K+≥6.0 mmol/L) was <1%. A potassium 5.5–5.9 mmol/L occurred on ≥1 occasion over follow-up in 11 patients (nine on spironolactone) and was predicted by baseline potassium ≥5.0 mmol/L and eGFR ≤45 ml/min/1.73m2. Over follow-up, three patients experienced significant renal dysfunction but no patients withdrew due to intolerance or side effects. Changes in potassium, eGFR and systolic blood pressure were most apparent in the first 4 eeks. CONCLUSION Spironolactone was well tolerated in selected patients with early stage CKD. Strict monitoring over the first month of treatment followed by standard surveillance as for ACE inhibitors and ARBs is suggested. PMID:21950312
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Edwards, Nicola C; Steeds, Richard P; Chue, Colin D; Stewart, Paul M; Ferro, Charles J; Townend, Jonathan N
2012-03-01
Mineralocorticoid receptor blockade (MRBs) in combination with angiotensin converting enzyme (ACE) inhibitors and angiotensin-II receptor blockade (ARBs) improve prognostic markers of cardiovascular and renal disease in early stage chronic kidney disease (CKD). Concerns relating to the safety and tolerability of MRBs in CKD may limit their use in a non clinical trial setting. METHODS In the Chronic Renal Impairment in Birmingham II study, 115 patients with non-diabetic early stage CKD (eGFR 30-89ml/min/1.73m(2) ) received 25mg daily of spironolactone for 4 weeks before randomization to continuing treatment or placebo for a further 36 weeks. All patients were on ACE inhibitors and/or ARB therapy. Potassium and renal function were checked at weeks 1, 2, 4, 8, 16, 28 and 40. The incidence of hyperkalaemia, significant renal dysfunction (reduction eGFR ≥25%) and adverse effects was assessed. After 40 weeks of treatment the incidence of serious hyperkalaemia (K(+) ≥6.0mmol/L) was <1%. A potassium 5.5-5.9mmol/L occurred on ≥1 occasion over follow-up in 11 patients (nine on spironolactone) and was predicted by baseline potassium ≥5.0mmol/L and eGFR ≤45 ml/min/1.73m(2) . Over follow-up, three patients experienced significant renal dysfunction but no patients withdrew due to intolerance or side effects. Changes in potassium, eGFR and systolic blood pressure were most apparent in the first 4 eeks. Spironolactone was well tolerated in selected patients with early stage CKD. Strict monitoring over the first month of treatment followed by standard surveillance as for ACE inhibitors and ARBs is suggested. © 2011 The Authors. British Journal of Clinical Pharmacology © 2011 The British Pharmacological Society.
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Stephens, Robert F.; Guan, W.; Zhorov, Boris S.; Spafford, J. David
2015-01-01
How nature discriminates sodium from calcium ions in eukaryotic channels has been difficult to resolve because they contain four homologous, but markedly different repeat domains. We glean clues from analyzing the changing pore region in sodium, calcium and NALCN channels, from single-cell eukaryotes to mammals. Alternative splicing in invertebrate homologs provides insights into different structural features underlying calcium and sodium selectivity. NALCN generates alternative ion selectivity with splicing that changes the high field strength (HFS) site at the narrowest level of the hourglass shaped pore where the selectivity filter is located. Alternative splicing creates NALCN isoforms, in which the HFS site has a ring of glutamates contributed by all four repeat domains (EEEE), or three glutamates and a lysine residue in the third (EEKE) or second (EKEE) position. Alternative splicing provides sodium and/or calcium selectivity in T-type channels with extracellular loops between S5 and P-helices (S5P) of different lengths that contain three or five cysteines. All eukaryotic channels have a set of eight core cysteines in extracellular regions, but the T-type channels have an infusion of 4–12 extra cysteines in extracellular regions. The pattern of conservation suggests a possible pairing of long loops in Domains I and III, which are bridged with core cysteines in NALCN, Cav, and Nav channels, and pairing of shorter loops in Domains II and IV in T-type channel through disulfide bonds involving T-type specific cysteines. Extracellular turrets of increasing lengths in potassium channels (Kir2.2, hERG, and K2P1) contribute to a changing landscape above the pore selectivity filter that can limit drug access and serve as an ion pre-filter before ions reach the pore selectivity filter below. Pairing of extended loops likely contributes to the large extracellular appendage as seen in single particle electron cryo-microscopy images of the eel Nav1 channel. PMID
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Mercator Ocean Forecasting Products: Fitting into the Users Needs
NASA Astrophysics Data System (ADS)
Baudel, S.; Toumazou, V.
2006-07-01
Mercator O cean is a French public initiative aimed to develop ocean forecast op erational systems based on ocean physical models assimilating routin ely r emote sensing (altimetry from Envisat, Jason-1, GFO and Topex/Poseidon), sea surface temperature (in the years to come SMO S sea surf ace salinities) and in situ data. The oth er essen tial and subsequent mission is to allow, to contr ibute and to further operational o ceanography downstream applications. For th at purpose, Mercator Ocean mak es its products available through two different ways: 1. Imag es on the web targeting the g eneral public Every w eek, more than 3000 maps are updated describ ing 3D modelled ocean: now cast, forecast for up to 14 d ays and hind cast, temp erature, salinity, surface current and other ocean par ameters, 5 dep ths from surface to bottom. These images ar e freely av ailab le on the web , excep t the zonal maps younger than 30 day s. For these, the user is expected to fill an on-line form, asking h is/her motiv ations and the use h e/she in tends to do w ith these maps. This con trolled access allows us to dr aw the profile of this aud ience: 370 users ( end of February 2006), represented by the "g eneral public" ( about 40%), resear chers (16%), sailing (13%), studen ts- teachers (10 %), public institutions (8%), in charge of State missions concerning oil dr ift prev ention, environment monitoring, and recreative or professional fishing (7 %). 2. Dig ital files targeting professional u ses The use of d igital files containing the Mer cator outpu ts 3D fields is th e most impor tant criter ia to evaluate the impact of th e usefulness of our products. Mercator has created 'showcase products', summar izing Mercator outpu ts on regular grid s in NetCDF format. Sever al ways are proposed to access these products : FTP and H TTP, in clud ing a LAS/Op endap server, wh ich allows the user to make extraction of a per iod/area/ver tical levels/ocean parameters, and enab ling continuous