Feature Discovery by Competitive Learning.
ERIC Educational Resources Information Center
Rumelhart, David E.; Zipser, David
1985-01-01
Reports results of studies with an unsupervised learning paradigm called competitive learning which is examined using computer simulation and formal analysis. When competitive learning is applied to parallel networks of neuron-like elements, many potentially useful learning tasks can be accomplished. (Author)
Approximate kernel competitive learning.
Wu, Jian-Sheng; Zheng, Wei-Shi; Lai, Jian-Huang
2015-03-01
Kernel competitive learning has been successfully used to achieve robust clustering. However, kernel competitive learning (KCL) is not scalable for large scale data processing, because (1) it has to calculate and store the full kernel matrix that is too large to be calculated and kept in the memory and (2) it cannot be computed in parallel. In this paper we develop a framework of approximate kernel competitive learning for processing large scale dataset. The proposed framework consists of two parts. First, it derives an approximate kernel competitive learning (AKCL), which learns kernel competitive learning in a subspace via sampling. We provide solid theoretical analysis on why the proposed approximation modelling would work for kernel competitive learning, and furthermore, we show that the computational complexity of AKCL is largely reduced. Second, we propose a pseudo-parallelled approximate kernel competitive learning (PAKCL) based on a set-based kernel competitive learning strategy, which overcomes the obstacle of using parallel programming in kernel competitive learning and significantly accelerates the approximate kernel competitive learning for large scale clustering. The empirical evaluation on publicly available datasets shows that the proposed AKCL and PAKCL can perform comparably as KCL, with a large reduction on computational cost. Also, the proposed methods achieve more effective clustering performance in terms of clustering precision against related approximate clustering approaches. Copyright © 2014 Elsevier Ltd. All rights reserved.
Assaying gene function by growth competition experiment.
Merritt, Joshua; Edwards, Jeremy S
2004-07-01
High-throughput screening and analysis is one of the emerging paradigms in biotechnology. In particular, high-throughput methods are essential in the field of functional genomics because of the vast amount of data generated in recent and ongoing genome sequencing efforts. In this report we discuss integrated functional analysis methodologies which incorporate both a growth competition component and a highly parallel assay used to quantify results of the growth competition. Several applications of the two most widely used technologies in the field, i.e., transposon mutagenesis and deletion strain library growth competition, and individual applications of several developing or less widely reported technologies are presented.
Costa-Font, Joan; Kanavos, Panos
2007-01-01
To examine the effects of parallel simvastatin importation on drug price in three of the main parallel importing countries in the European Union, namely the United Kingdom, Germany, and the Netherlands. To estimate the market share of parallel imported simvastatin and the unit price -both locally produced and parallel imported- adjusted by defined daily dose in the importing country and in the exporting country (Spain). Ordinary least squares regression was used to examine the potential price competition resulting from parallel drug trade between 1997 and 2002. The market share of parallel imported simvastatin progressively expanded (especially in the United Kingdom and Germany) in the period examined, although the price difference between parallel imported and locally sourced simvastatin was not significant. Prices tended to rise in the United Kingdom and Germany and declined in the Netherlands. We found no evidence of pro-competitive effects resulting from the expansion of parallel trade. The development of parallel drug importation in the European Union produced unexpected effects (limited competition) on prices that differ from those expected by the introduction of a new competitor. This is partially the result of drug price regulation scant incentives to competition and of the lack of transparency in the drug reimbursement system, especially due to the effect of informal discounts (not observable to researchers). The case of simvastatin reveals that savings to the health system from parallel trade are trivial. Finally, of the three countries examined, the only country that shows a moderate downward pattern in simvastatin prices is the Netherlands. This effect can be attributed to the existence of a system that claws back informal discounts.
Parallel imports and the pricing of pharmaceutical products: evidence from the European Union.
Ganslandt, Mattias; Maskus, Keith E
2004-09-01
We consider policy issues regarding parallel imports (PIs) of brand-name pharmaceuticals in the European Union, where such trade is permitted. We develop a simple model in which an original manufacturer competes in its home market with PI firms. The model suggests that for small trade costs the original manufacturer will accommodate the import decisions of parallel traders and that the price in the home market falls as the volume of parallel imports rises. Using data from Sweden we find that the prices of drugs subject to competition from parallel imports fell relative to other drugs over the period 1994-1999. Econometric analysis finds that parallel imports significantly reduced manufacturing prices, by 12-19%. There is evidence that this effect increases with multiple PI entrants.
How pattern is selected in drift wave turbulence: Role of parallel flow shear
NASA Astrophysics Data System (ADS)
Kosuga, Y.
2017-12-01
The role of parallel shear flow in the pattern selection problem in drift wave turbulence is discussed. Patterns of interest here are E × B convective cells, which include poloidally symmetric zonal flows and radially elongated streamers. The competition between zonal flow formation and streamer formation is analyzed in the context of modulational instability analysis, with the parallel flow shear as a parameter. For drift wave turbulence with k⊥ρs ≲ O (1 ) and without parallel flow coupling, zonal flows are preferred structures. While increasing the magnitude of parallel flow shear, streamer growth overcomes zonal flow growth. This is because the self-focusing effect of the modulational instability becomes more effective for streamers through density and parallel velocity modulation. As a consequence, the bursty release of free energy may result as the parallel flow shear increases.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Malony, Allen D; Shende, Sameer
The primary goal of the University of Oregon's DOE "ÃÂcompetitiveness" project was to create performance technology that embodies and supports knowledge of performance data, analysis, and diagnosis in parallel performance problem solving. The target of our development activities was the TAU Performance System and the technology accomplishments reported in this and prior reports have all been incorporated in the TAU open software distribution. In addition, the project has been committed to maintaining strong interactions with the DOE SciDAC Performance Engineering Research Institute (PERI) and Center for Technology for Advanced Scientific Component Software (TASCS). This collaboration has proved valuable for translationmore » of our knowledge-based performance techniques to parallel application development and performance engineering practice. Our outreach has also extended to the DOE Advanced CompuTational Software (ACTS) collection and project. Throughout the project we have participated in the PERI and TASCS meetings, as well as the ACTS annual workshops.« less
Competitive Parallel Processing For Compression Of Data
NASA Technical Reports Server (NTRS)
Diner, Daniel B.; Fender, Antony R. H.
1990-01-01
Momentarily-best compression algorithm selected. Proposed competitive-parallel-processing system compresses data for transmission in channel of limited band-width. Likely application for compression lies in high-resolution, stereoscopic color-television broadcasting. Data from information-rich source like color-television camera compressed by several processors, each operating with different algorithm. Referee processor selects momentarily-best compressed output.
Cuozzo, John W; Centrella, Paolo A; Gikunju, Diana; Habeshian, Sevan; Hupp, Christopher D; Keefe, Anthony D; Sigel, Eric A; Soutter, Holly H; Thomson, Heather A; Zhang, Ying; Clark, Matthew A
2017-05-04
We have identified and characterized novel potent inhibitors of Bruton's tyrosine kinase (BTK) from a single DNA-encoded library of over 110 million compounds by using multiple parallel selection conditions, including variation in target concentration and addition of known binders to provide competition information. Distinct binding profiles were observed by comparing enrichments of library building block combinations under these conditions; one enriched only at high concentrations of BTK and was competitive with ATP, and another enriched at both high and low concentrations of BTK and was not competitive with ATP. A compound representing the latter profile showed low nanomolar potency in biochemical and cellular BTK assays. Results from kinetic mechanism of action studies were consistent with the selection profiles. Analysis of the co-crystal structure of the most potent compound demonstrated a novel binding mode that revealed a new pocket in BTK. Our results demonstrate that profile-based selection strategies using DNA-encoded libraries form the basis of a new methodology to rapidly identify small molecule inhibitors with novel binding modes to clinically relevant targets. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Structural modeling of carbonaceous mesophase amphotropic mixtures under uniaxial extensional flow.
Golmohammadi, Mojdeh; Rey, Alejandro D
2010-07-21
The extended Maier-Saupe model for binary mixtures of model carbonaceous mesophases (uniaxial discotic nematogens) under externally imposed flow, formulated in previous studies [M. Golmohammadi and A. D. Rey, Liquid Crystals 36, 75 (2009); M. Golmohammadi and A. D. Rey, Entropy 10, 183 (2008)], is used to characterize the effect of uniaxial extensional flow and concentration on phase behavior and structure of these mesogenic blends. The generic thermorheological phase diagram of the single-phase binary mixture, given in terms of temperature (T) and Deborah (De) number, shows the existence of four T-De transition lines that define regions that correspond to the following quadrupolar tensor order parameter structures: (i) oblate (perpendicular, parallel), (ii) prolate (perpendicular, parallel), (iii) scalene O(perpendicular, parallel), and (iv) scalene P(perpendicular, parallel), where the symbols (perpendicular, parallel) indicate alignment of the tensor order ellipsoid with respect to the extension axis. It is found that with increasing T the dominant component of the mixture exhibits weak deviations from the well-known pure species response to uniaxial extensional flow (uniaxial perpendicular nematic-->biaxial nematic-->uniaxial parallel paranematic). In contrast, the slaved component shows a strong deviation from the pure species response. This deviation is dictated by the asymmetric viscoelastic coupling effects emanating from the dominant component. Changes in conformation (oblate <==> prolate) and orientation (perpendicular <==> parallel) are effected through changes in pairs of eigenvalues of the quadrupolar tensor order parameter. The complexity of the structural sensitivity to temperature and extensional flow is a reflection of the dual lyotropic/thermotropic nature (amphotropic nature) of the mixture and their cooperation/competition. The analysis demonstrates that the simple structures (biaxial nematic and uniaxial paranematic) observed in pure discotic mesogens under uniaxial extensional flow are significantly enriched by the interaction of the lyotropic/thermotropic competition with the binary molecular architectures and with the quadrupolar nature of the flow.
Nobrega, R Paul; Brown, Michael; Williams, Cody; Sumner, Chris; Estep, Patricia; Caffry, Isabelle; Yu, Yao; Lynaugh, Heather; Burnina, Irina; Lilov, Asparouh; Desroches, Jordan; Bukowski, John; Sun, Tingwan; Belk, Jonathan P; Johnson, Kirt; Xu, Yingda
2017-10-01
The state-of-the-art industrial drug discovery approach is the empirical interrogation of a library of drug candidates against a target molecule. The advantage of high-throughput kinetic measurements over equilibrium assessments is the ability to measure each of the kinetic components of binding affinity. Although high-throughput capabilities have improved with advances in instrument hardware, three bottlenecks in data processing remain: (1) intrinsic molecular properties that lead to poor biophysical quality in vitro are not accounted for in commercially available analysis models, (2) processing data through a user interface is time-consuming and not amenable to parallelized data collection, and (3) a commercial solution that includes historical kinetic data in the analysis of kinetic competition data does not exist. Herein, we describe a generally applicable method for the automated analysis, storage, and retrieval of kinetic binding data. This analysis can deconvolve poor quality data on-the-fly and store and organize historical data in a queryable format for use in future analyses. Such database-centric strategies afford greater insight into the molecular mechanisms of kinetic competition, allowing for the rapid identification of allosteric effectors and the presentation of kinetic competition data in absolute terms of percent bound to antigen on the biosensor.
Parallel language activation and cognitive control during spoken word recognition in bilinguals
Blumenfeld, Henrike K.; Marian, Viorica
2013-01-01
Accounts of bilingual cognitive advantages suggest an associative link between cross-linguistic competition and inhibitory control. We investigate this link by examining English-Spanish bilinguals’ parallel language activation during auditory word recognition and nonlinguistic Stroop performance. Thirty-one English-Spanish bilinguals and 30 English monolinguals participated in an eye-tracking study. Participants heard words in English (e.g., comb) and identified corresponding pictures from a display that included pictures of a Spanish competitor (e.g., conejo, English rabbit). Bilinguals with higher Spanish proficiency showed more parallel language activation and smaller Stroop effects than bilinguals with lower Spanish proficiency. Across all bilinguals, stronger parallel language activation between 300–500ms after word onset was associated with smaller Stroop effects; between 633–767ms, reduced parallel language activation was associated with smaller Stroop effects. Results suggest that bilinguals who perform well on the Stroop task show increased cross-linguistic competitor activation during early stages of word recognition and decreased competitor activation during later stages of word recognition. Findings support the hypothesis that cross-linguistic competition impacts domain-general inhibition. PMID:24244842
Competition of Perpendicular and Parallel Flows in a Straight Magnetic Field
NASA Astrophysics Data System (ADS)
Li, Jiacong; Diamond, Patrick; Hong, Rongjie; Tynan, George
2017-10-01
In tokamaks, intrinsic rotations in both toroidal and poloidal directions are important for the stability and confinement. Since they compete for energy from background turbulence, the coupling of them is the key to understanding the physics of turbulent state and transport bifurcations, e.g. L-H transition. V⊥ can affect the parallel Reynolds stress via cross phase and energetics, and thus regulates the parallel flow generation. In return, the turbulence driven V∥ plays a role in the mean vorticity flux, influencing the generation of V⊥. Also, competition of intrinsic azimuthal and axial flows is observed in CSDX-a linear plasma device with straight magnetic fields. CSDX is a well diagnosed venue to study the basic physics of turbulence-flow interactions in straight magnetic fields. Here, we study the turbulent energy branching between the turbulence driven parallel flow and perpendicular flow. Specifically, the ratio between parallel and perpendicular Reynolds power decreases when the mean perpendicular flow increases. As the mean parallel flow increases, this ratio first increases and then decreases before the parallel flow shear hits the parallel shear flow instability threshold. We seek to understand the flow states and compare with CSDX experiments. This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of Fusion Energy Sciences, under Award Number DE-FG02-04ER54738.
Language Learning and Control in Monolinguals and Bilinguals
ERIC Educational Resources Information Center
Bartolotti, James; Marian, Viorica
2012-01-01
Parallel language activation in bilinguals leads to competition between languages. Experience managing this interference may aid novel language learning by improving the ability to suppress competition from known languages. To investigate the effect of bilingualism on the ability to control native-language interference, monolinguals and bilinguals…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1994-02-02
This report consists of three separate but related reports. They are (1) Human Resource Development, (2) Carbon-based Structural Materials Research Cluster, and (3) Data Parallel Algorithms for Scientific Computing. To meet the objectives of the Human Resource Development plan, the plan includes K--12 enrichment activities, undergraduate research opportunities for students at the state`s two Historically Black Colleges and Universities, graduate research through cluster assistantships and through a traineeship program targeted specifically to minorities, women and the disabled, and faculty development through participation in research clusters. One research cluster is the chemistry and physics of carbon-based materials. The objective of thismore » cluster is to develop a self-sustaining group of researchers in carbon-based materials research within the institutions of higher education in the state of West Virginia. The projects will involve analysis of cokes, graphites and other carbons in order to understand the properties that provide desirable structural characteristics including resistance to oxidation, levels of anisotropy and structural characteristics of the carbons themselves. In the proposed cluster on parallel algorithms, research by four WVU faculty and three state liberal arts college faculty are: (1) modeling of self-organized critical systems by cellular automata; (2) multiprefix algorithms and fat-free embeddings; (3) offline and online partitioning of data computation; and (4) manipulating and rendering three dimensional objects. This cluster furthers the state Experimental Program to Stimulate Competitive Research plan by building on existing strengths at WVU in parallel algorithms.« less
A parallel algorithm for the eigenvalues and eigenvectors for a general complex matrix
NASA Technical Reports Server (NTRS)
Shroff, Gautam
1989-01-01
A new parallel Jacobi-like algorithm is developed for computing the eigenvalues of a general complex matrix. Most parallel methods for this parallel typically display only linear convergence. Sequential norm-reducing algorithms also exit and they display quadratic convergence in most cases. The new algorithm is a parallel form of the norm-reducing algorithm due to Eberlein. It is proven that the asymptotic convergence rate of this algorithm is quadratic. Numerical experiments are presented which demonstrate the quadratic convergence of the algorithm and certain situations where the convergence is slow are also identified. The algorithm promises to be very competitive on a variety of parallel architectures.
Peng, Wei; Crouse, Julia
2013-06-01
Although multiplayer modes are common among contemporary video games, the bulk of game research focuses on the single-player mode. To fill the gap in the literature, the current study investigated the effects of different multiplayer modes on enjoyment, future play motivation, and the actual physical activity intensity in an active video game. One hundred sixty-two participants participated in a one-factor between-subject laboratory experiment with three conditions: (a) single player: play against self pretest score; (b) cooperation with another player in the same physical space; (c) parallel competition with another player in separated physical spaces. We found that parallel competition in separate physical spaces was the optimal mode, since it resulted in both high enjoyment and future play motivation and high physical intensity. Implications for future research on multiplayer mode and play space as well as active video game-based physical activity interventions are discussed.
Chen, Qi; Mirman, Daniel
2012-04-01
One of the core principles of how the mind works is the graded, parallel activation of multiple related or similar representations. Parallel activation of multiple representations has been particularly important in the development of theories and models of language processing, where coactivated representations (neighbors) have been shown to exhibit both facilitative and inhibitory effects on word recognition and production. Researchers generally ascribe these effects to interactive activation and competition, but there is no unified explanation for why the effects are facilitative in some cases and inhibitory in others. We present a series of simulations of a simple domain-general interactive activation and competition model that is broadly consistent with more specialized domain-specific models of lexical processing. The results showed that interactive activation and competition can indeed account for the complex pattern of reversals. Critically, the simulations revealed a core computational principle that determines whether neighbor effects are facilitative or inhibitory: strongly active neighbors exert a net inhibitory effect, and weakly active neighbors exert a net facilitative effect.
Game Theoretic Models of Competition and Upgrade Investments in Communication Networks
ERIC Educational Resources Information Center
Wu, Shuang
2010-01-01
In the first part of this dissertation, we study the competition among network service providers in a parallel-link network with the presence of elastic user demand that diminishes both with higher prices and congestion. First we analyze a game where providers strategically price their service for single class of traffic. Later we analyze a game…
ERIC Educational Resources Information Center
Chen, Qi; Mirman, Daniel
2012-01-01
One of the core principles of how the mind works is the graded, parallel activation of multiple related or similar representations. Parallel activation of multiple representations has been particularly important in the development of theories and models of language processing, where coactivated representations ("neighbors") have been shown to…
Gere, Attila; Losó, Viktor; Györey, Annamária; Kovács, Sándor; Huzsvai, László; Nábrádi, András; Kókai, Zoltán; Sipos, László
2014-12-01
Traditional internal and external preference mapping methods are based on principal component analysis (PCA). However, parallel factor analysis (PARAFAC) and Tucker-3 methods could be a better choice. To evaluate the methods, preference maps of sweet corn varieties will be introduced. A preference map of eight sweet corn varieties was established using PARAFAC and Tucker-3 methods. Instrumental data were also integrated into the maps. The triplot created by the PARAFAC model explains better how odour is separated from texture or appearance, and how some varieties are separated from others. Internal and external preference maps were created using parallel factor analysis (PARAFAC) and Tucker-3 models employing both sensory (trained panel and consumers) and instrumental parameters simultaneously. Triplots of the applied three-way models have a competitive advantage compared to the traditional biplots of the PCA-based external preference maps. The solution of PARAFAC and Tucker-3 is very similar regarding the interpretation of the first and third factors. The main difference is due to the second factor as it differentiated the attributes better. Consumers who prefer 'super sweet' varieties (they place great emphasis especially on taste) are much younger and have significantly higher incomes, and buy sweet corn products rarely (once a month). Consumers who consume sweet corn products mainly because of their texture and appearance are significantly older and include a higher ratio of men. © 2014 Society of Chemical Industry.
Massively Parallel Processing for Fast and Accurate Stamping Simulations
NASA Astrophysics Data System (ADS)
Gress, Jeffrey J.; Xu, Siguang; Joshi, Ramesh; Wang, Chuan-tao; Paul, Sabu
2005-08-01
The competitive automotive market drives automotive manufacturers to speed up the vehicle development cycles and reduce the lead-time. Fast tooling development is one of the key areas to support fast and short vehicle development programs (VDP). In the past ten years, the stamping simulation has become the most effective validation tool in predicting and resolving all potential formability and quality problems before the dies are physically made. The stamping simulation and formability analysis has become an critical business segment in GM math-based die engineering process. As the simulation becomes as one of the major production tools in engineering factory, the simulation speed and accuracy are the two of the most important measures for stamping simulation technology. The speed and time-in-system of forming analysis becomes an even more critical to support the fast VDP and tooling readiness. Since 1997, General Motors Die Center has been working jointly with our software vendor to develop and implement a parallel version of simulation software for mass production analysis applications. By 2001, this technology was matured in the form of distributed memory processing (DMP) of draw die simulations in a networked distributed memory computing environment. In 2004, this technology was refined to massively parallel processing (MPP) and extended to line die forming analysis (draw, trim, flange, and associated spring-back) running on a dedicated computing environment. The evolution of this technology and the insight gained through the implementation of DM0P/MPP technology as well as performance benchmarks are discussed in this publication.
Evolutionary disarmament in interspecific competition.
Kisdi, E; Geritz, S A
2001-12-22
Competitive asymmetry, which is the advantage of having a larger body or stronger weaponry than a contestant, drives spectacular evolutionary arms races in intraspecific competition. Similar asymmetries are well documented in interspecific competition, yet they seldom lead to exaggerated traits. Here we demonstrate that two species with substantially different size may undergo parallel coevolution towards a smaller size under the same ecological conditions where a single species would exhibit an evolutionary arms race. We show that disarmament occurs for a wide range of parameters in an ecologically explicit model of competition for a single shared resource; disarmament also occurs in a simple Lotka-Volterra competition model. A key property of both models is the interplay between evolutionary dynamics and population density. The mechanism does not rely on very specific features of the model. Thus, evolutionary disarmament may be widespread and may help to explain the lack of interspecific arms races.
Evolutionary disarmament in interspecific competition.
Kisdi, E.; Geritz, S. A.
2001-01-01
Competitive asymmetry, which is the advantage of having a larger body or stronger weaponry than a contestant, drives spectacular evolutionary arms races in intraspecific competition. Similar asymmetries are well documented in interspecific competition, yet they seldom lead to exaggerated traits. Here we demonstrate that two species with substantially different size may undergo parallel coevolution towards a smaller size under the same ecological conditions where a single species would exhibit an evolutionary arms race. We show that disarmament occurs for a wide range of parameters in an ecologically explicit model of competition for a single shared resource; disarmament also occurs in a simple Lotka-Volterra competition model. A key property of both models is the interplay between evolutionary dynamics and population density. The mechanism does not rely on very specific features of the model. Thus, evolutionary disarmament may be widespread and may help to explain the lack of interspecific arms races. PMID:11749715
Implementation of the NAS Parallel Benchmarks in Java
NASA Technical Reports Server (NTRS)
Frumkin, Michael A.; Schultz, Matthew; Jin, Haoqiang; Yan, Jerry; Biegel, Bryan (Technical Monitor)
2002-01-01
Several features make Java an attractive choice for High Performance Computing (HPC). In order to gauge the applicability of Java to Computational Fluid Dynamics (CFD), we have implemented the NAS (NASA Advanced Supercomputing) Parallel Benchmarks in Java. The performance and scalability of the benchmarks point out the areas where improvement in Java compiler technology and in Java thread implementation would position Java closer to Fortran in the competition for CFD applications.
Performance and Scalability of the NAS Parallel Benchmarks in Java
NASA Technical Reports Server (NTRS)
Frumkin, Michael A.; Schultz, Matthew; Jin, Haoqiang; Yan, Jerry; Biegel, Bryan A. (Technical Monitor)
2002-01-01
Several features make Java an attractive choice for scientific applications. In order to gauge the applicability of Java to Computational Fluid Dynamics (CFD), we have implemented the NAS (NASA Advanced Supercomputing) Parallel Benchmarks in Java. The performance and scalability of the benchmarks point out the areas where improvement in Java compiler technology and in Java thread implementation would position Java closer to Fortran in the competition for scientific applications.
Reticulocyte profile in top-level alpine skiers during four consecutive competitive seasons.
Banfi, Giuseppe; Tavana, Rodolfo; Freschi, Marco; Lundby, Carsten
2010-06-01
The role of reticulocytes (Ret) in sports medicine became clear when the count of immature erythrocytes was introduced in protocols used for anti-doping purposes. Because specific research regarding seasonal variations in Ret is lacking, we assessed Ret (and [Hb]) in top-level male and female skiers during four consecutive competitive seasons. A difference (P < 0.05) between males and females was found for [Hb] and Ret values: [Hb] was lower and Ret was higher in females. The difference was maintained across all four competitive seasons. Marked within-subject differences in [Hb], Ret and immature reticulocyte fraction values were noted; the within-subject variability was greater than the between-subject variability in both genders. For instance, a difference for Ret was consistently shown between first and second blood drawings, i.e. between basal value, before the start of training and competition, and the value at middle of season, when training workload was at highest level. Unlike Ret%, the analysis of variance showed significant changes in [Hb] values across competitive seasons for both genders. Comparison between consecutive seasons (e.g., 2005-2006 vs. 2006-2007) showed significant differences for both parameters. The behaviour of [Hb] and Ret during the various seasons was parallel in females, whereas a discrepancy existed in males. In general, inter-individual variability is quite high, thus, Ret and [Hb] modifications should be referred only to the single athlete. We confirm the validity of the use of Ret counts for anti-doping purposes.
Parallel multigrid smoothing: polynomial versus Gauss-Seidel
NASA Astrophysics Data System (ADS)
Adams, Mark; Brezina, Marian; Hu, Jonathan; Tuminaro, Ray
2003-07-01
Gauss-Seidel is often the smoother of choice within multigrid applications. In the context of unstructured meshes, however, maintaining good parallel efficiency is difficult with multiplicative iterative methods such as Gauss-Seidel. This leads us to consider alternative smoothers. We discuss the computational advantages of polynomial smoothers within parallel multigrid algorithms for positive definite symmetric systems. Two particular polynomials are considered: Chebyshev and a multilevel specific polynomial. The advantages of polynomial smoothing over traditional smoothers such as Gauss-Seidel are illustrated on several applications: Poisson's equation, thin-body elasticity, and eddy current approximations to Maxwell's equations. While parallelizing the Gauss-Seidel method typically involves a compromise between a scalable convergence rate and maintaining high flop rates, polynomial smoothers achieve parallel scalable multigrid convergence rates without sacrificing flop rates. We show that, although parallel computers are the main motivation, polynomial smoothers are often surprisingly competitive with Gauss-Seidel smoothers on serial machines.
Implementation of NAS Parallel Benchmarks in Java
NASA Technical Reports Server (NTRS)
Frumkin, Michael; Schultz, Matthew; Jin, Hao-Qiang; Yan, Jerry
2000-01-01
A number of features make Java an attractive but a debatable choice for High Performance Computing (HPC). In order to gauge the applicability of Java to the Computational Fluid Dynamics (CFD) we have implemented NAS Parallel Benchmarks in Java. The performance and scalability of the benchmarks point out the areas where improvement in Java compiler technology and in Java thread implementation would move Java closer to Fortran in the competition for CFD applications.
Extended MHD modeling of tearing-driven magnetic relaxation
NASA Astrophysics Data System (ADS)
Sauppe, J. P.; Sovinec, C. R.
2017-05-01
Discrete relaxation events in reversed-field pinch relevant configurations are investigated numerically with nonlinear extended magnetohydrodynamic (MHD) modeling, including the Hall term in Ohm's law and first-order ion finite Larmor radius effects. Results show variability among relaxation events, where the Hall dynamo effect may help or impede the MHD dynamo effect in relaxing the parallel current density profile. The competitive behavior arises from multi-helicity conditions where the dominant magnetic fluctuation is relatively small. The resulting changes in parallel current density and parallel flow are aligned in the core, consistent with experimental observations. The analysis of simulation results also confirms that the force density from fluctuation-induced Reynolds stress arises subsequent to the drive from the fluctuation-induced Lorentz force density. Transport of the momentum density is found to be dominated by the fluctuation-induced Maxwell stress over most of the cross section with viscous and gyroviscous contributions being large in the edge region. The findings resolve a discrepancy with respect to the relative orientation of current density and flow relaxation, which had not been realized or investigated in King et al. [Phys. Plasmas 19, 055905 (2012)], where only the magnitude of flow relaxation is actually consistent with experimental results.
GPU computing in medical physics: a review.
Pratx, Guillem; Xing, Lei
2011-05-01
The graphics processing unit (GPU) has emerged as a competitive platform for computing massively parallel problems. Many computing applications in medical physics can be formulated as data-parallel tasks that exploit the capabilities of the GPU for reducing processing times. The authors review the basic principles of GPU computing as well as the main performance optimization techniques, and survey existing applications in three areas of medical physics, namely image reconstruction, dose calculation and treatment plan optimization, and image processing.
Parallel computing using a Lagrangian formulation
NASA Technical Reports Server (NTRS)
Liou, May-Fun; Loh, Ching Yuen
1991-01-01
A new Lagrangian formulation of the Euler equation is adopted for the calculation of 2-D supersonic steady flow. The Lagrangian formulation represents the inherent parallelism of the flow field better than the common Eulerian formulation and offers a competitive alternative on parallel computers. The implementation of the Lagrangian formulation on the Thinking Machines Corporation CM-2 Computer is described. The program uses a finite volume, first-order Godunov scheme and exhibits high accuracy in dealing with multidimensional discontinuities (slip-line and shock). By using this formulation, a better than six times speed-up was achieved on a 8192-processor CM-2 over a single processor of a CRAY-2.
Parallel computing using a Lagrangian formulation
NASA Technical Reports Server (NTRS)
Liou, May-Fun; Loh, Ching-Yuen
1992-01-01
This paper adopts a new Lagrangian formulation of the Euler equation for the calculation of two dimensional supersonic steady flow. The Lagrangian formulation represents the inherent parallelism of the flow field better than the common Eulerian formulation and offers a competitive alternative on parallel computers. The implementation of the Lagrangian formulation on the Thinking Machines Corporation CM-2 Computer is described. The program uses a finite volume, first-order Godunov scheme and exhibits high accuracy in dealing with multidimensional discontinuities (slip-line and shock). By using this formulation, we have achieved better than six times speed-up on a 8192-processor CM-2 over a single processor of a CRAY-2.
Decision making by superimposing information from parallel cognitive channels
NASA Astrophysics Data System (ADS)
Aityan, Sergey K.
1993-08-01
A theory of decision making with perception through parallel information channels is presented. Decision making is considered a parallel competitive process. Every channel can provide confirmation or rejection of a decision concept. Different channels provide different impact on the specific concepts caused by the goals and individual cognitive features. All concepts are divided into semantic clusters due to the goals and the system defaults. The clusters can be alternative or complimentary. The 'winner-take-all' concept nodes firing takes place within the alternative cluster. Concepts can be independently activated in the complimentary cluster. A cognitive channel affects a decision concept by sending an activating or inhibitory signal. The complimentary clusters serve for building up complex concepts by superimposing activation received from various channels. The decision making is provided by the alternative clusters. Every active concept in the alternative cluster tends to suppress the competitive concepts in the cluster by sending inhibitory signals to the other nodes of the cluster. The model accounts for a time delay in signal transmission between the nodes and explains decreasing of the reaction time if information is confirmed by different channels and increasing of the reaction time if deceiving information received from the channels.
Faust, Oliver; Yu, Wenwei; Rajendra Acharya, U
2015-03-01
The concept of real-time is very important, as it deals with the realizability of computer based health care systems. In this paper we review biomedical real-time systems with a meta-analysis on computational complexity (CC), delay (Δ) and speedup (Sp). During the review we found that, in the majority of papers, the term real-time is part of the thesis indicating that a proposed system or algorithm is practical. However, these papers were not considered for detailed scrutiny. Our detailed analysis focused on papers which support their claim of achieving real-time, with a discussion on CC or Sp. These papers were analyzed in terms of processing system used, application area (AA), CC, Δ, Sp, implementation/algorithm (I/A) and competition. The results show that the ideas of parallel processing and algorithm delay were only recently introduced and journal papers focus more on Algorithm (A) development than on implementation (I). Most authors compete on big O notation (O) and processing time (PT). Based on these results, we adopt the position that the concept of real-time will continue to play an important role in biomedical systems design. We predict that parallel processing considerations, such as Sp and algorithm scaling, will become more important. Copyright © 2015 Elsevier Ltd. All rights reserved.
Spatially parallel processing of within-dimension conjunctions.
Linnell, K J; Humphreys, G W
2001-01-01
Within-dimension conjunction search for red-green targets amongst red-blue, and blue-green, nontargets is extremely inefficient (Wolfe et al, 1990 Journal of Experimental Psychology: Human Perception and Performance 16 879-892). We tested whether pairs of red-green conjunction targets can nevertheless be processed spatially in parallel. Participants made speeded detection responses whenever a red-green target was present. Across trials where a second identical target was present, the distribution of detection times was compatible with the assumption that targets were processed in parallel (Miller, 1982 Cognitive Psychology 14 247-279). We show that this was not an artifact of response-competition or feature-based processing. We suggest that within-dimension conjunctions can be processed spatially in parallel. Visual search for such items may be inefficient owing to within-dimension grouping between items.
Han, S; Humphreys, G W; Chen, L
1999-10-01
The role of perceptual grouping and the encoding of closure of local elements in the processing of hierarchical patterns was studied. Experiments 1 and 2 showed a global advantage over the local level for 2 tasks involving the discrimination of orientation and closure, but there was a local advantage for the closure discrimination task relative to the orientation discrimination task. Experiment 3 showed a local precedence effect for the closure discrimination task when local element grouping was weakened by embedding the stimuli from Experiment 1 in a background made up of cross patterns. Experiments 4A and 4B found that dissimilarity of closure between the local elements of hierarchical stimuli and the background figures could facilitate the grouping of closed local elements and enhanced the perception of global structure. Experiment 5 showed that the advantage for detecting the closure of local elements in hierarchical analysis also held under divided- and selective-attention conditions. Results are consistent with the idea that grouping between local elements takes place in parallel and competes with the computation of closure of local elements in determining the selection between global and local levels of hierarchical patterns for response.
Robinson, Catherine D.; Auchtung, Jennifer M.; Collins, James
2014-01-01
Clostridium difficile infection is the most common cause of severe cases of antibiotic-associated diarrhea (AAD) and is a significant health burden. Recent increases in the rate of C. difficile infection have paralleled the emergence of a specific phylogenetic clade of C. difficile strains (ribotype 027; North American pulsed-field electrophoresis 1 [NAP1]; restriction endonuclease analysis [REA] group BI). Initial reports indicated that ribotype 027 strains were associated with increased morbidity and mortality and might be hypervirulent. Although subsequent work has raised some doubt as to whether ribotype 027 strains are hypervirulent, the strains are considered epidemic isolates that have caused severe outbreaks across the globe. We hypothesized that one factor that could lead to the increased prevalence of ribotype 027 strains would be if these strains had increased competitive fitness compared to strains of other ribotypes. We developed a moderate-throughput in vitro model of C. difficile infection and used it to test competition between four ribotype 027 clinical isolates and clinical isolates of four other ribotypes (001, 002, 014, and 053). We found that ribotype 027 strains outcompeted the strains of other ribotypes. A similar competitive advantage was observed when two ribotype pairs were competed in a mouse model of C. difficile infection. Based upon these results, we conclude that one possible mechanism through which ribotype 027 strains have caused outbreaks worldwide is their increased ability to compete in the presence of a complex microbiota. PMID:24733099
The cost of parallel consolidation into visual working memory.
Rideaux, Reuben; Edwards, Mark
2016-01-01
A growing body of evidence indicates that information can be consolidated into visual working memory in parallel. Initially, it was suggested that color information could be consolidated in parallel while orientation was strictly limited to serial consolidation (Liu & Becker, 2013). However, we recently found evidence suggesting that both orientation and motion direction items can be consolidated in parallel, with different levels of accuracy (Rideaux, Apthorp, & Edwards, 2015). Here we examine whether there is a cost associated with parallel consolidation of orientation and direction information by comparing performance, in terms of precision and guess rate, on a target recall task where items are presented either sequentially or simultaneously. The results compellingly indicate that motion direction can be consolidated in parallel, but the evidence for orientation is less conclusive. Further, we find that there is a twofold cost associated with parallel consolidation of direction: Both the probability of failing to consolidate one (or both) item/s increases and the precision at which representations are encoded is reduced. Additionally, we find evidence indicating that the increased consolidation failure may be due to interference between items presented simultaneously, and is moderated by item similarity. These findings suggest that a biased competition model may explain differences in parallel consolidation between features.
NASA Astrophysics Data System (ADS)
Zerr, Robert Joseph
2011-12-01
The integral transport matrix method (ITMM) has been used as the kernel of new parallel solution methods for the discrete ordinates approximation of the within-group neutron transport equation. The ITMM abandons the repetitive mesh sweeps of the traditional source iterations (SI) scheme in favor of constructing stored operators that account for the direct coupling factors among all the cells and between the cells and boundary surfaces. The main goals of this work were to develop the algorithms that construct these operators and employ them in the solution process, determine the most suitable way to parallelize the entire procedure, and evaluate the behavior and performance of the developed methods for increasing number of processes. This project compares the effectiveness of the ITMM with the SI scheme parallelized with the Koch-Baker-Alcouffe (KBA) method. The primary parallel solution method involves a decomposition of the domain into smaller spatial sub-domains, each with their own transport matrices, and coupled together via interface boundary angular fluxes. Each sub-domain has its own set of ITMM operators and represents an independent transport problem. Multiple iterative parallel solution methods have investigated, including parallel block Jacobi (PBJ), parallel red/black Gauss-Seidel (PGS), and parallel GMRES (PGMRES). The fastest observed parallel solution method, PGS, was used in a weak scaling comparison with the PARTISN code. Compared to the state-of-the-art SI-KBA with diffusion synthetic acceleration (DSA), this new method without acceleration/preconditioning is not competitive for any problem parameters considered. The best comparisons occur for problems that are difficult for SI DSA, namely highly scattering and optically thick. SI DSA execution time curves are generally steeper than the PGS ones. However, until further testing is performed it cannot be concluded that SI DSA does not outperform the ITMM with PGS even on several thousand or tens of thousands of processors. The PGS method does outperform SI DSA for the periodic heterogeneous layers (PHL) configuration problems. Although this demonstrates a relative strength/weakness between the two methods, the practicality of these problems is much less, further limiting instances where it would be beneficial to select ITMM over SI DSA. The results strongly indicate a need for a robust, stable, and efficient acceleration method (or preconditioner for PGMRES). The spatial multigrid (SMG) method is currently incomplete in that it does not work for all cases considered and does not effectively improve the convergence rate for all values of scattering ratio c or cell dimension h. Nevertheless, it does display the desired trend for highly scattering, optically thin problems. That is, it tends to lower the rate of growth of number of iterations with increasing number of processes, P, while not increasing the number of additional operations per iteration to the extent that the total execution time of the rapidly converging accelerated iterations exceeds that of the slower unaccelerated iterations. A predictive parallel performance model has been developed for the PBJ method. Timing tests were performed such that trend lines could be fitted to the data for the different components and used to estimate the execution times. Applied to the weak scaling results, the model notably underestimates construction time, but combined with a slight overestimation in iterative solution time, the model predicts total execution time very well for large P. It also does a decent job with the strong scaling results, closely predicting the construction time and time per iteration, especially as P increases. Although not shown to be competitive up to 1,024 processing elements with the current state of the art, the parallelized ITMM exhibits promising scaling trends. Ultimately, compared to the KBA method, the parallelized ITMM may be found to be a very attractive option for transport calculations spatially decomposed over several tens of thousands of processes. Acceleration/preconditioning of the parallelized ITMM once developed will improve the convergence rate and improve its competitiveness. (Abstract shortened by UMI.)
Large-scale parallel genome assembler over cloud computing environment.
Das, Arghya Kusum; Koppa, Praveen Kumar; Goswami, Sayan; Platania, Richard; Park, Seung-Jong
2017-06-01
The size of high throughput DNA sequencing data has already reached the terabyte scale. To manage this huge volume of data, many downstream sequencing applications started using locality-based computing over different cloud infrastructures to take advantage of elastic (pay as you go) resources at a lower cost. However, the locality-based programming model (e.g. MapReduce) is relatively new. Consequently, developing scalable data-intensive bioinformatics applications using this model and understanding the hardware environment that these applications require for good performance, both require further research. In this paper, we present a de Bruijn graph oriented Parallel Giraph-based Genome Assembler (GiGA), as well as the hardware platform required for its optimal performance. GiGA uses the power of Hadoop (MapReduce) and Giraph (large-scale graph analysis) to achieve high scalability over hundreds of compute nodes by collocating the computation and data. GiGA achieves significantly higher scalability with competitive assembly quality compared to contemporary parallel assemblers (e.g. ABySS and Contrail) over traditional HPC cluster. Moreover, we show that the performance of GiGA is significantly improved by using an SSD-based private cloud infrastructure over traditional HPC cluster. We observe that the performance of GiGA on 256 cores of this SSD-based cloud infrastructure closely matches that of 512 cores of traditional HPC cluster.
SO{sub 2} trading program as a metaphor for a competitive electric industry
DOE Office of Scientific and Technical Information (OSTI.GOV)
O`Connor, P.R.
1996-12-31
This very brief presentation focuses on the competitive market impacts of sulfur dioxide SO{sub 2} emissions trading. Key points of the presentation are highlighted in four tables. The main principles and results of the emissions trading program are outlined, and the implications of SO{sub 2} trading for the electric industry are listed. Parallels between SO{sub 2} trading and electric utility restructing identified include no market distortion by avoiding serious disadvantages to competitors, and avoidance of stranded costs through compliance flexibility. 4 tabs.
Analog system for computing sparse codes
Rozell, Christopher John; Johnson, Don Herrick; Baraniuk, Richard Gordon; Olshausen, Bruno A.; Ortman, Robert Lowell
2010-08-24
A parallel dynamical system for computing sparse representations of data, i.e., where the data can be fully represented in terms of a small number of non-zero code elements, and for reconstructing compressively sensed images. The system is based on the principles of thresholding and local competition that solves a family of sparse approximation problems corresponding to various sparsity metrics. The system utilizes Locally Competitive Algorithms (LCAs), nodes in a population continually compete with neighboring units using (usually one-way) lateral inhibition to calculate coefficients representing an input in an over complete dictionary.
A smart-pixel holographic competitive learning network
NASA Astrophysics Data System (ADS)
Slagle, Timothy Michael
Neural networks are adaptive classifiers which modify their decision boundaries based on feedback from externally- or internally-generated error signals. Optics is an attractive technology for neural network implementation because it offers the possibility of parallel, nearly instantaneous computation of the weighted neuron inputs by the propagation of light through the optical system. Using current optical device technology, system performance levels of 3 × 1011 connection updates per second can be achieved. This thesis presents an architecture for an optical competitive learning network which offers advantages over previous optical implementations, including smart-pixel-based optical neurons, phase- conjugate self-alignment of a single neuron plane, and high-density, parallel-access weight storage, interconnection, and learning in a volume hologram. The competitive learning algorithm with modifications for optical implementation is described, and algorithm simulations are performed for an example problem. The optical competitive learning architecture is then introduced. The optical system is simulated using the ``beamprop'' algorithm at the level of light propagating through the system components, and results showing competitive learning operation in agreement with the algorithm simulations are presented. The optical competitive learning requires a non-linear, non-local ``winner-take-all'' (WTA) neuron function. Custom-designed smart-pixel WTA neuron arrays were fabricated using CMOS VLSI/liquid crystal technology. Results of laboratory tests of the WTA arrays' switching characteristics, time response, and uniformity are then presented. The system uses a phase-conjugate mirror to write the self-aligning interconnection weight holograms, and energy gain is required from the reflection to minimize erasure of the existing weights. An experimental system for characterizing the PCM response is described. Useful gains of 20 were obtained with a polarization-multiplexed PCM readout, and gains of up to 60 were observed when a time-sequential read-out technique was used. Finally, the optical competitive learning laboratory system is described, including some necessary modifications to the previous architectures, and the data acquisition and control system developed for the system. Experimental results showing phase conjugation of the WTA outputs, holographic interconnect storage, associative storage between input images and WTA neuron outputs, and WTA array switching are presented, demonstrating the functions necessary for the operation of the optical learning system.
Improving competitiveness through performance-measurement systems.
Stewart, L J; Lockamy, A
2001-12-01
Parallels exist between the competitive pressures felt by U.S. manufacturers over the past 30 years and those experienced by healthcare providers today. Increasing market deregulation, changing government policies, and growing consumerism have altered the healthcare arena. Responding to similar pressures, manufacturers adopted a strategic orientation driven by customer needs and expectations that led them to achieve high performance levels and surpass their competition. The adoption of integrated performance-measurement systems was instrumental in these firms' success. An integrated performance-measurement model for healthcare organizations can help to blend the organization's strategy with the demands of the contemporary healthcare environment. Performance-measurement systems encourage healthcare organizations to focus on their mission and vision by aligning their strategic objectives and resource-allocation decisions with customer requirements.
ERIC Educational Resources Information Center
Siiner, Maarja
2016-01-01
Nation states increasingly assign the responsibility for meeting the global competitiveness agenda to the universities themselves [Cirius, 2009, "Mobilitetsstatistik for de videregaaende uddannelser 2007/08" [Mobility statistics for higher education 2007/08
Evaluating the performance of the particle finite element method in parallel architectures
NASA Astrophysics Data System (ADS)
Gimenez, Juan M.; Nigro, Norberto M.; Idelsohn, Sergio R.
2014-05-01
This paper presents a high performance implementation for the particle-mesh based method called particle finite element method two (PFEM-2). It consists of a material derivative based formulation of the equations with a hybrid spatial discretization which uses an Eulerian mesh and Lagrangian particles. The main aim of PFEM-2 is to solve transport equations as fast as possible keeping some level of accuracy. The method was found to be competitive with classical Eulerian alternatives for these targets, even in their range of optimal application. To evaluate the goodness of the method with large simulations, it is imperative to use of parallel environments. Parallel strategies for Finite Element Method have been widely studied and many libraries can be used to solve Eulerian stages of PFEM-2. However, Lagrangian stages, such as streamline integration, must be developed considering the parallel strategy selected. The main drawback of PFEM-2 is the large amount of memory needed, which limits its application to large problems with only one computer. Therefore, a distributed-memory implementation is urgently needed. Unlike a shared-memory approach, using domain decomposition the memory is automatically isolated, thus avoiding race conditions; however new issues appear due to data distribution over the processes. Thus, a domain decomposition strategy for both particle and mesh is adopted, which minimizes the communication between processes. Finally, performance analysis running over multicore and multinode architectures are presented. The Courant-Friedrichs-Lewy number used influences the efficiency of the parallelization and, in some cases, a weighted partitioning can be used to improve the speed-up. However the total cputime for cases presented is lower than that obtained when using classical Eulerian strategies.
Competition policy in patent cases and antitrust.
Sobel, Gerald
2003-01-01
The article that follows examines the competition policy reflected in the decisions of the Court of Appeals for the Federal Circuit in its patent cases. The court's views on this subject have been manifested most plainly in decisions that have transformed the law concerning infringement under the doctrine of equivalents and claim construction. In both categories, the court narrowed patent scope by reason of its desire to protect competitors. The article argues that the court's premise in prescribing narrower claim scope reflected an incomplete view of competition policy. The court's analysis overlooked the benefits to competition provided by patents, which stimulate inventions and their development. The article traces the development of antitrust jurisprudence and demonstrates how respect for the contribution of patents to competition and skepticism of free-riding has evolved, particularly beginning in the 1970s. The article draws a parallel between the Court's reasoning about competition policy, on the one hand, and the rejected views of Justices Hugo Black and William O. Douglas and abandoned patent-antitrust jurisprudence, on the other. The Federal Circuit's decision in Festo Corp. v. Shoketsu Kinzoku Kogyo Kabushiki Co., Ltd., 234 F.3d 558 (Fed. Cir. 2000), on the subject of equivalents is considered in the paper. In that decision, the majority adopted a new rule that completely barred infringement under the doctrine of equivalents of any claim limitation where, in prosecution, there had been a narrowing amendment relating to patentability. In the past, prosecution estoppel foreclosing equivalents had been subject to a "flexible bar," which, in some circumstances, allowed for equivalence notwithstanding such an amendment. The article points out that because almost all patents are amended during prosecution, the effect would be to allow widespread copying of patented inventions by trivial modifications of any narrowed claim limitation. The incentive to innovate in the future would be correspondingly diminished and the expectations of past patentees would be correspondingly altered.
Parallel Frames and Policy Narratives in Music Education and Physical Education
ERIC Educational Resources Information Center
Freer, Patrick K.
2012-01-01
The relationship between music education and physical education has often been portrayed as a competition for financial resources, student enrollment, instructional time, and community support. This article instead explores commonalities between the two disciplines, including their histories, curricular debates, shared concerns, mutual challenges,…
Competitive Genomic Screens of Barcoded Yeast Libraries
Urbanus, Malene; Proctor, Michael; Heisler, Lawrence E.; Giaever, Guri; Nislow, Corey
2011-01-01
By virtue of advances in next generation sequencing technologies, we have access to new genome sequences almost daily. The tempo of these advances is accelerating, promising greater depth and breadth. In light of these extraordinary advances, the need for fast, parallel methods to define gene function becomes ever more important. Collections of genome-wide deletion mutants in yeasts and E. coli have served as workhorses for functional characterization of gene function, but this approach is not scalable, current gene-deletion approaches require each of the thousands of genes that comprise a genome to be deleted and verified. Only after this work is complete can we pursue high-throughput phenotyping. Over the past decade, our laboratory has refined a portfolio of competitive, miniaturized, high-throughput genome-wide assays that can be performed in parallel. This parallelization is possible because of the inclusion of DNA 'tags', or 'barcodes,' into each mutant, with the barcode serving as a proxy for the mutation and one can measure the barcode abundance to assess mutant fitness. In this study, we seek to fill the gap between DNA sequence and barcoded mutant collections. To accomplish this we introduce a combined transposon disruption-barcoding approach that opens up parallel barcode assays to newly sequenced, but poorly characterized microbes. To illustrate this approach we present a new Candida albicans barcoded disruption collection and describe how both microarray-based and next generation sequencing-based platforms can be used to collect 10,000 - 1,000,000 gene-gene and drug-gene interactions in a single experiment. PMID:21860376
Afshar, Yaser; Sbalzarini, Ivo F.
2016-01-01
Modern fluorescence microscopy modalities, such as light-sheet microscopy, are capable of acquiring large three-dimensional images at high data rate. This creates a bottleneck in computational processing and analysis of the acquired images, as the rate of acquisition outpaces the speed of processing. Moreover, images can be so large that they do not fit the main memory of a single computer. We address both issues by developing a distributed parallel algorithm for segmentation of large fluorescence microscopy images. The method is based on the versatile Discrete Region Competition algorithm, which has previously proven useful in microscopy image segmentation. The present distributed implementation decomposes the input image into smaller sub-images that are distributed across multiple computers. Using network communication, the computers orchestrate the collectively solving of the global segmentation problem. This not only enables segmentation of large images (we test images of up to 1010 pixels), but also accelerates segmentation to match the time scale of image acquisition. Such acquisition-rate image segmentation is a prerequisite for the smart microscopes of the future and enables online data compression and interactive experiments. PMID:27046144
Afshar, Yaser; Sbalzarini, Ivo F
2016-01-01
Modern fluorescence microscopy modalities, such as light-sheet microscopy, are capable of acquiring large three-dimensional images at high data rate. This creates a bottleneck in computational processing and analysis of the acquired images, as the rate of acquisition outpaces the speed of processing. Moreover, images can be so large that they do not fit the main memory of a single computer. We address both issues by developing a distributed parallel algorithm for segmentation of large fluorescence microscopy images. The method is based on the versatile Discrete Region Competition algorithm, which has previously proven useful in microscopy image segmentation. The present distributed implementation decomposes the input image into smaller sub-images that are distributed across multiple computers. Using network communication, the computers orchestrate the collectively solving of the global segmentation problem. This not only enables segmentation of large images (we test images of up to 10(10) pixels), but also accelerates segmentation to match the time scale of image acquisition. Such acquisition-rate image segmentation is a prerequisite for the smart microscopes of the future and enables online data compression and interactive experiments.
Strand, Julia F
2014-03-01
A widely agreed-upon feature of spoken word recognition is that multiple lexical candidates in memory are simultaneously activated in parallel when a listener hears a word, and that those candidates compete for recognition (Luce, Goldinger, Auer, & Vitevitch, Perception 62:615-625, 2000; Luce & Pisoni, Ear and Hearing 19:1-36, 1998; McClelland & Elman, Cognitive Psychology 18:1-86, 1986). Because the presence of those competitors influences word recognition, much research has sought to quantify the processes of lexical competition. Metrics that quantify lexical competition continuously are more effective predictors of auditory and visual (lipread) spoken word recognition than are the categorical metrics traditionally used (Feld & Sommers, Speech Communication 53:220-228, 2011; Strand & Sommers, Journal of the Acoustical Society of America 130:1663-1672, 2011). A limitation of the continuous metrics is that they are somewhat computationally cumbersome and require access to existing speech databases. This article describes the Phi-square Lexical Competition Database (Phi-Lex): an online, searchable database that provides access to multiple metrics of auditory and visual (lipread) lexical competition for English words, available at www.juliastrand.com/phi-lex .
David Hull's generalized natural selection as an explanation for scientific change
NASA Astrophysics Data System (ADS)
Little, Michelle Yvette
2001-10-01
Philosophers of science such as Karl Popper and Thomas Kuhn have employed evolutionary idiom in describing scientific change. In Science as a Process (1988) Hull makes evolutionary theory explanatorily applicable. He modifies key evolutionary terms in order that both biological evolution and scientific change are instances of a general selection process. According to Hull, because of naturally-existing competition for credit among researchers and the professional lineages they constitute, scientists are constrained to cooperate and collaborate. This process entails two important philosophical consequences. First, it allows for a natural justification of why the sciences can provide objective empirical knowledge. Second, appreciating its strength means that a philosophical analysis of scientific change is solidly difficult features to combine. I work on strengthening two weaknesses in Hull's arguments. First, operating in his analysis is an unexplicated notion of ``information'' running parallel to the equally opaque notion of genetic information. My third chapter provides a clear account of ``genetic information'' whose usefulness extends beyond the assistance it can render Hull as a clear concept is needed in biological contexts as well. The fourth and fifth chapters submit evidence of scientific change from radio astronomy. Hull insists on empirical backing for philosophical theses but his own book stands to suffer from selection effects as it offers cases drawn from a single subspecialty in the biological sciences. I found that in the main scientists and the change they propel accords well with Hull's explanation. However, instances of major change reveal credit- and resource-sharing to a degree contrary with what Hull would expect. My conclusion is that the naturalness of competition, instantiated during the course of standardized and relatively ``normal'' scientific research, is not the norm during periods of new research and its uncertain standards of protocol. As such my position is an inversion of the relationship Hull views between cooperation and competition in scientific change. Cooperation is a precondition for competition, rather than the other way around.
Review of "Education Olympics 2008: The Games in Review"
ERIC Educational Resources Information Center
Fierros, Edward G.; Kornhaber, Mindy
2008-01-01
This review examines the recently released Thomas P. Fordham Institute report, "Education Olympics: The Games in Review." Published just after the completion of the 2008 Beijing Summer Olympics, Education Olympics strategically parallels the international competition by awarding gold, silver and bronze medals to top performing countries based on…
Vasseur, David A; Fox, Jeremy W
2011-10-01
Consumers acquire essential nutrients by ingesting the tissues of resource species. When these tissues contain essential nutrients in a suboptimal ratio, consumers may benefit from ingesting a mixture of nutritionally complementary resource species. We investigate the joint ecological and evolutionary consequences of competition for complementary resources, using an adaptive dynamics model of two consumers and two resources that differ in their relative content of two essential nutrients. In the absence of competition, a nutritionally balanced diet rarely maximizes fitness because of the dynamic feedbacks between uptake rate and resource density, whereas in sympatry, nutritionally balanced diets maximize fitness because competing consumers with different nutritional requirements tend to equalize the relative abundances of the two resources. Adaptation from allopatric to sympatric fitness optima can generate character convergence, divergence, and parallel shifts, depending not on the degree of diet overlap but on the match between resource nutrient content and consumer nutrient requirements. Contrary to previous verbal arguments that suggest that character convergence leads to neutral stability, coadaptation of competing consumers always leads to stable coexistence. Furthermore, we show that incorporating costs of consuming or excreting excess nonlimiting nutrients selects for nutritionally balanced diets and so promotes character convergence. This article demonstrates that resource-use overlap has little bearing on coexistence when resources are nutritionally complementary, and it highlights the importance of using mathematical models to infer the stability of ecoevolutionary dynamics.
Myria: Scalable Analytics as a Service
NASA Astrophysics Data System (ADS)
Howe, B.; Halperin, D.; Whitaker, A.
2014-12-01
At the UW eScience Institute, we're working to empower non-experts, especially in the sciences, to write and use data-parallel algorithms. To this end, we are building Myria, a web-based platform for scalable analytics and data-parallel programming. Myria's internal model of computation is the relational algebra extended with iteration, such that every program is inherently data-parallel, just as every query in a database is inherently data-parallel. But unlike databases, iteration is a first class concept, allowing us to express machine learning tasks, graph traversal tasks, and more. Programs can be expressed in a number of languages and can be executed on a number of execution environments, but we emphasize a particular language called MyriaL that supports both imperative and declarative styles and a particular execution engine called MyriaX that uses an in-memory column-oriented representation and asynchronous iteration. We deliver Myria over the web as a service, providing an editor, performance analysis tools, and catalog browsing features in a single environment. We find that this web-based "delivery vector" is critical in reaching non-experts: they are insulated from irrelevant effort technical work associated with installation, configuration, and resource management. The MyriaX backend, one of several execution runtimes we support, is a main-memory, column-oriented, RDBMS-on-the-worker system that supports cyclic data flows as a first-class citizen and has been shown to outperform competitive systems on 100-machine cluster sizes. I will describe the Myria system, give a demo, and present some new results in large-scale oceanographic microbiology.
Exploration of operator method digital optical computers for application to NASA
NASA Technical Reports Server (NTRS)
1990-01-01
Digital optical computer design has been focused primarily towards parallel (single point-to-point interconnection) implementation. This architecture is compared to currently developing VHSIC systems. Using demonstrated multichannel acousto-optic devices, a figure of merit can be formulated. The focus is on a figure of merit termed Gate Interconnect Bandwidth Product (GIBP). Conventional parallel optical digital computer architecture demonstrates only marginal competitiveness at best when compared to projected semiconductor implements. Global, analog global, quasi-digital, and full digital interconnects are briefly examined as alternative to parallel digital computer architecture. Digital optical computing is becoming a very tough competitor to semiconductor technology since it can support a very high degree of three dimensional interconnect density and high degrees of Fan-In without capacitive loading effects at very low power consumption levels.
Wang, Yong-Jian; Shi, Xue-Ping; Meng, Xue-Feng; Wu, Xiao-Jing; Luo, Fang-Li; Yu, Fei-Hai
2016-01-01
Spatial heterogeneity in two co-variable resources such as light and water availability is common and can affect the growth of clonal plants. Several studies have tested effects of spatial heterogeneity in the supply of a single resource on competitive interactions of plants, but none has examined those of heterogeneous distribution of two co-variable resources. In a greenhouse experiment, we grew one (without intraspecific competition) or nine isolated ramets (with competition) of a rhizomatous herb Iris japonica under a homogeneous environment and four heterogeneous environments differing in patch arrangement (reciprocal and parallel patchiness of light and soil water) and patch scale (large and small patches of light and water). Intraspecific competition significantly decreased the growth of I. japonica, but at the whole container level there were no significant interaction effects of competition by spatial heterogeneity or significant effect of heterogeneity on competitive intensity. Irrespective of competition, the growth of I. japonica in the high and the low water patches did not differ significantly in the homogeneous treatments, but it was significantly larger in the high than in the low water patches in the heterogeneous treatments with large patches. For the heterogeneous treatments with small patches, the growth of I. japonica was significantly larger in the high than in the low water patches in the presence of competition, but such an effect was not significant in the absence of competition. Furthermore, patch arrangement and patch scale significantly affected competitive intensity at the patch level. Therefore, spatial heterogeneity in light and water supply can alter intraspecific competition at the patch level and such effects depend on patch arrangement and patch scale. PMID:27375630
Wang, Yong-Jian; Shi, Xue-Ping; Meng, Xue-Feng; Wu, Xiao-Jing; Luo, Fang-Li; Yu, Fei-Hai
2016-01-01
Spatial heterogeneity in two co-variable resources such as light and water availability is common and can affect the growth of clonal plants. Several studies have tested effects of spatial heterogeneity in the supply of a single resource on competitive interactions of plants, but none has examined those of heterogeneous distribution of two co-variable resources. In a greenhouse experiment, we grew one (without intraspecific competition) or nine isolated ramets (with competition) of a rhizomatous herb Iris japonica under a homogeneous environment and four heterogeneous environments differing in patch arrangement (reciprocal and parallel patchiness of light and soil water) and patch scale (large and small patches of light and water). Intraspecific competition significantly decreased the growth of I. japonica, but at the whole container level there were no significant interaction effects of competition by spatial heterogeneity or significant effect of heterogeneity on competitive intensity. Irrespective of competition, the growth of I. japonica in the high and the low water patches did not differ significantly in the homogeneous treatments, but it was significantly larger in the high than in the low water patches in the heterogeneous treatments with large patches. For the heterogeneous treatments with small patches, the growth of I. japonica was significantly larger in the high than in the low water patches in the presence of competition, but such an effect was not significant in the absence of competition. Furthermore, patch arrangement and patch scale significantly affected competitive intensity at the patch level. Therefore, spatial heterogeneity in light and water supply can alter intraspecific competition at the patch level and such effects depend on patch arrangement and patch scale.
The influence of electric field and confinement on cell motility.
Huang, Yu-Ja; Samorajski, Justin; Kreimer, Rachel; Searson, Peter C
2013-01-01
The ability of cells to sense and respond to endogenous electric fields is important in processes such as wound healing, development, and nerve regeneration. In cell culture, many epithelial and endothelial cell types respond to an electric field of magnitude similar to endogenous electric fields by moving preferentially either parallel or antiparallel to the field vector, a process known as galvanotaxis. Here we report on the influence of dc electric field and confinement on the motility of fibroblast cells using a chip-based platform. From analysis of cell paths we show that the influence of electric field on motility is much more complex than simply imposing a directional bias towards the cathode or anode. The cell velocity, directedness, as well as the parallel and perpendicular components of the segments along the cell path are dependent on the magnitude of the electric field. Forces in the directions perpendicular and parallel to the electric field are in competition with one another in a voltage-dependent manner, which ultimately govern the trajectories of the cells in the presence of an electric field. To further investigate the effects of cell reorientation in the presence of a field, cells are confined within microchannels to physically prohibit the alignment seen in 2D environment. Interestingly, we found that confinement results in an increase in cell velocity both in the absence and presence of an electric field compared to migration in 2D.
Lü, Qiang; Xia, Xiao-Yan; Chen, Rong; Miao, Da-Jun; Chen, Sha-Sha; Quan, Li-Jun; Li, Hai-Ou
2012-01-01
Protein structure prediction (PSP), which is usually modeled as a computational optimization problem, remains one of the biggest challenges in computational biology. PSP encounters two difficult obstacles: the inaccurate energy function problem and the searching problem. Even if the lowest energy has been luckily found by the searching procedure, the correct protein structures are not guaranteed to obtain. A general parallel metaheuristic approach is presented to tackle the above two problems. Multi-energy functions are employed to simultaneously guide the parallel searching threads. Searching trajectories are in fact controlled by the parameters of heuristic algorithms. The parallel approach allows the parameters to be perturbed during the searching threads are running in parallel, while each thread is searching the lowest energy value determined by an individual energy function. By hybridizing the intelligences of parallel ant colonies and Monte Carlo Metropolis search, this paper demonstrates an implementation of our parallel approach for PSP. 16 classical instances were tested to show that the parallel approach is competitive for solving PSP problem. This parallel approach combines various sources of both searching intelligences and energy functions, and thus predicts protein conformations with good quality jointly determined by all the parallel searching threads and energy functions. It provides a framework to combine different searching intelligence embedded in heuristic algorithms. It also constructs a container to hybridize different not-so-accurate objective functions which are usually derived from the domain expertise.
Lü, Qiang; Xia, Xiao-Yan; Chen, Rong; Miao, Da-Jun; Chen, Sha-Sha; Quan, Li-Jun; Li, Hai-Ou
2012-01-01
Background Protein structure prediction (PSP), which is usually modeled as a computational optimization problem, remains one of the biggest challenges in computational biology. PSP encounters two difficult obstacles: the inaccurate energy function problem and the searching problem. Even if the lowest energy has been luckily found by the searching procedure, the correct protein structures are not guaranteed to obtain. Results A general parallel metaheuristic approach is presented to tackle the above two problems. Multi-energy functions are employed to simultaneously guide the parallel searching threads. Searching trajectories are in fact controlled by the parameters of heuristic algorithms. The parallel approach allows the parameters to be perturbed during the searching threads are running in parallel, while each thread is searching the lowest energy value determined by an individual energy function. By hybridizing the intelligences of parallel ant colonies and Monte Carlo Metropolis search, this paper demonstrates an implementation of our parallel approach for PSP. 16 classical instances were tested to show that the parallel approach is competitive for solving PSP problem. Conclusions This parallel approach combines various sources of both searching intelligences and energy functions, and thus predicts protein conformations with good quality jointly determined by all the parallel searching threads and energy functions. It provides a framework to combine different searching intelligence embedded in heuristic algorithms. It also constructs a container to hybridize different not-so-accurate objective functions which are usually derived from the domain expertise. PMID:23028708
Kinetics and evolved gas analysis for pyrolysis of food processing wastes using TGA/MS/FT-IR.
Özsin, Gamzenur; Pütün, Ayşe Eren
2017-06-01
The objective of this study was to identify the pyrolysis of different bio-waste produced by food processing industry in a comprehensible manner. For this purpose, pyrolysis behaviors of chestnut shells (CNS), cherry stones (CS) and grape seeds (GS) were investigated by thermogravimetric analysis (TGA) combined with a Fourier-transform infrared (FT-IR) spectrometer and a mass spectrometer (MS). In order to make available theoretical groundwork for biomass pyrolysis, activation energies were calculated with the help of four different model-free kinetic methods. The results are attributed to the complex reaction schemes which imply parallel, competitive and complex reactions during pyrolysis. During pyrolysis, the evolution of volatiles was also characterized by FT-IR and MS. The main evolved gases were determined as H 2 O, CO 2 and hydrocarbons such as CH 4 and temperature dependent profiles of the species were obtained. Copyright © 2017 Elsevier Ltd. All rights reserved.
Sensorimotor Learning Biases Choice Behavior: A Learning Neural Field Model for Decision Making
Schöner, Gregor; Gail, Alexander
2012-01-01
According to a prominent view of sensorimotor processing in primates, selection and specification of possible actions are not sequential operations. Rather, a decision for an action emerges from competition between different movement plans, which are specified and selected in parallel. For action choices which are based on ambiguous sensory input, the frontoparietal sensorimotor areas are considered part of the common underlying neural substrate for selection and specification of action. These areas have been shown capable of encoding alternative spatial motor goals in parallel during movement planning, and show signatures of competitive value-based selection among these goals. Since the same network is also involved in learning sensorimotor associations, competitive action selection (decision making) should not only be driven by the sensory evidence and expected reward in favor of either action, but also by the subject's learning history of different sensorimotor associations. Previous computational models of competitive neural decision making used predefined associations between sensory input and corresponding motor output. Such hard-wiring does not allow modeling of how decisions are influenced by sensorimotor learning or by changing reward contingencies. We present a dynamic neural field model which learns arbitrary sensorimotor associations with a reward-driven Hebbian learning algorithm. We show that the model accurately simulates the dynamics of action selection with different reward contingencies, as observed in monkey cortical recordings, and that it correctly predicted the pattern of choice errors in a control experiment. With our adaptive model we demonstrate how network plasticity, which is required for association learning and adaptation to new reward contingencies, can influence choice behavior. The field model provides an integrated and dynamic account for the operations of sensorimotor integration, working memory and action selection required for decision making in ambiguous choice situations. PMID:23166483
Between Competition Imperative and Europeanisation: The Case of Higher Education Reform in Poland
ERIC Educational Resources Information Center
Dakowska, Dorota
2015-01-01
While the Europeanisation of Higher Education (HE) systems has triggered much debate, the relationship between European factors and domestic economic processes, has been less thoroughly analysed. This article analyses HE reforms in the light of two parallel processes, which have shaped this sector: the introduction of market mechanisms and a…
Three is much more than two in coarsening dynamics of cyclic competitions
NASA Astrophysics Data System (ADS)
Mitarai, Namiko; Gunnarson, Ivar; Pedersen, Buster Niels; Rosiek, Christian Anker; Sneppen, Kim
2016-04-01
The classical game of rock-paper-scissors has inspired experiments and spatial model systems that address the robustness of biological diversity. In particular, the game nicely illustrates that cyclic interactions allow multiple strategies to coexist for long-time intervals. When formulated in terms of a one-dimensional cellular automata, the spatial distribution of strategies exhibits coarsening with algebraically growing domain size over time, while the two-dimensional version allows domains to break and thereby opens the possibility for long-time coexistence. We consider a quasi-one-dimensional implementation of the cyclic competition, and study the long-term dynamics as a function of rare invasions between parallel linear ecosystems. We find that increasing the complexity from two to three parallel subsystems allows a transition from complete coarsening to an active steady state where the domain size stays finite. We further find that this transition happens irrespective of whether the update is done in parallel for all sites simultaneously or done randomly in sequential order. In both cases, the active state is characterized by localized bursts of dislocations, followed by longer periods of coarsening. In the case of the parallel dynamics, we find that there is another phase transition between the active steady state and the coarsening state within the three-line system when the invasion rate between the subsystems is varied. We identify the critical parameter for this transition and show that the density of active boundaries has critical exponents that are consistent with the directed percolation universality class. On the other hand, numerical simulations with the random sequential dynamics suggest that the system may exhibit an active steady state as long as the invasion rate is finite.
NASA Astrophysics Data System (ADS)
2012-12-01
The University of Edinburgh, crowdsourcing website Kaggle and Winton Capital Management have joined forces to launch a competition to identify dark matter haloes. The Scientific Organizing Committee of the RAS National Astronomy Meeting 2013, the UK Solar Physics and Magnetosphere, Ionosphere and Solar-Terrestrial meetings, are seeking nominations for parallel discussion session themes. A winner of the 2012 Move an Asteroid Technical Paper Competition suggests painting asteroids white in order to boost their albedo and take advantage of solar radiation pressure to alter their orbits.
Parallel language activation and inhibitory control in bimodal bilinguals.
Giezen, Marcel R; Blumenfeld, Henrike K; Shook, Anthony; Marian, Viorica; Emmorey, Karen
2015-08-01
Findings from recent studies suggest that spoken-language bilinguals engage nonlinguistic inhibitory control mechanisms to resolve cross-linguistic competition during auditory word recognition. Bilingual advantages in inhibitory control might stem from the need to resolve perceptual competition between similar-sounding words both within and between their two languages. If so, these advantages should be lessened or eliminated when there is no perceptual competition between two languages. The present study investigated the extent of inhibitory control recruitment during bilingual language comprehension by examining associations between language co-activation and nonlinguistic inhibitory control abilities in bimodal bilinguals, whose two languages do not perceptually compete. Cross-linguistic distractor activation was identified in the visual world paradigm, and correlated significantly with performance on a nonlinguistic spatial Stroop task within a group of 27 hearing ASL-English bilinguals. Smaller Stroop effects (indexing more efficient inhibition) were associated with reduced co-activation of ASL signs during the early stages of auditory word recognition. These results suggest that inhibitory control in auditory word recognition is not limited to resolving perceptual linguistic competition in phonological input, but is also used to moderate competition that originates at the lexico-semantic level. Copyright © 2015 Elsevier B.V. All rights reserved.
A survey of GPU-based acceleration techniques in MRI reconstructions
Wang, Haifeng; Peng, Hanchuan; Chang, Yuchou
2018-01-01
Image reconstruction in magnetic resonance imaging (MRI) clinical applications has become increasingly more complicated. However, diagnostic and treatment require very fast computational procedure. Modern competitive platforms of graphics processing unit (GPU) have been used to make high-performance parallel computations available, and attractive to common consumers for computing massively parallel reconstruction problems at commodity price. GPUs have also become more and more important for reconstruction computations, especially when deep learning starts to be applied into MRI reconstruction. The motivation of this survey is to review the image reconstruction schemes of GPU computing for MRI applications and provide a summary reference for researchers in MRI community. PMID:29675361
A survey of GPU-based acceleration techniques in MRI reconstructions.
Wang, Haifeng; Peng, Hanchuan; Chang, Yuchou; Liang, Dong
2018-03-01
Image reconstruction in magnetic resonance imaging (MRI) clinical applications has become increasingly more complicated. However, diagnostic and treatment require very fast computational procedure. Modern competitive platforms of graphics processing unit (GPU) have been used to make high-performance parallel computations available, and attractive to common consumers for computing massively parallel reconstruction problems at commodity price. GPUs have also become more and more important for reconstruction computations, especially when deep learning starts to be applied into MRI reconstruction. The motivation of this survey is to review the image reconstruction schemes of GPU computing for MRI applications and provide a summary reference for researchers in MRI community.
Localization of basic fibroblast growth factor binding sites in the chick embryonic neural retina.
Cirillo, A; Arruti, C; Courtois, Y; Jeanny, J C
1990-12-01
We have investigated the localization of basic fibroblast growth factor (bFGF) binding sites during the development of the neural retina in the chick embryo. The specificity of the affinity of bFGF for its receptors was assessed by competition experiments with unlabelled growth factor or with heparin, as well as by heparitinase treatment of the samples. Two different types of binding sites were observed in the neural retina by light-microscopic autoradiography. The first type, localized mainly to basement membranes, was highly sensitive to heparitinase digestion and to competition with heparin. It was not developmentally regulated. The second type of binding site, resistant to heparin competition, appeared to be associated with retinal cells from the earliest stages studied (3-day-old embryo, stages 21-22 of Hamburger and Hamilton). Its distribution was found to vary during embryonic development, paralleling layering of the neural retina. Binding of bFGF to the latter sites was observed throughout the retinal neuroepithelium at early stages but displayed a distinct pattern at the time when the inner and outer plexiform layers were formed. During the development of the inner plexiform layer, a banded pattern of bFGF binding was observed. These bands, lying parallel to the vitreal surface, seemed to codistribute with the synaptic bands existing in the inner plexiform layer. The presence of intra-retinal bFGF binding sites whose distribution varies with embryonic development suggests a regulatory mechanism involving differential actions of bFGF on neural retinal cells.
Scaling Deep Learning workloads: NVIDIA DGX-1/Pascal and Intel Knights Landing
Gawande, Nitin A.; Daily, Jeff A.; Siegel, Charles; ...
2018-05-05
Deep Learning (DL) algorithms have become ubiquitous in data analytics. As a result, major computing vendors—including NVIDIA, Intel, AMD, and IBM—have architectural road maps influenced by DL workloads. Furthermore, several vendors have recently advertised new computing products as accelerating large DL workloads. Unfortunately, it is difficult for data scientists to quantify the potential of these different products. Here, this article provides a performance and power analysis of important DL workloads on two major parallel architectures: NVIDIA DGX-1 (eight Pascal P100 GPUs interconnected with NVLink) and Intel Knights Landing (KNL) CPUs interconnected with Intel Omni-Path or Cray Aries. Our evaluation consistsmore » of a cross section of convolutional neural net workloads: CifarNet, AlexNet, GoogLeNet, and ResNet50 topologies using the Cifar10 and ImageNet datasets. The workloads are vendor-optimized for each architecture. We use sequentially equivalent implementations to maintain iso-accuracy between parallel and sequential DL models. Our analysis indicates that although GPUs provide the highest overall performance, the gap can close for some convolutional networks; and the KNL can be competitive in performance/watt. We find that NVLink facilitates scaling efficiency on GPUs. However, its importance is heavily dependent on neural network architecture. Furthermore, for weak-scaling—sometimes encouraged by restricted GPU memory—NVLink is less important.« less
Scaling Deep Learning workloads: NVIDIA DGX-1/Pascal and Intel Knights Landing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gawande, Nitin A.; Daily, Jeff A.; Siegel, Charles
Deep Learning (DL) algorithms have become ubiquitous in data analytics. As a result, major computing vendors—including NVIDIA, Intel, AMD, and IBM—have architectural road maps influenced by DL workloads. Furthermore, several vendors have recently advertised new computing products as accelerating large DL workloads. Unfortunately, it is difficult for data scientists to quantify the potential of these different products. Here, this article provides a performance and power analysis of important DL workloads on two major parallel architectures: NVIDIA DGX-1 (eight Pascal P100 GPUs interconnected with NVLink) and Intel Knights Landing (KNL) CPUs interconnected with Intel Omni-Path or Cray Aries. Our evaluation consistsmore » of a cross section of convolutional neural net workloads: CifarNet, AlexNet, GoogLeNet, and ResNet50 topologies using the Cifar10 and ImageNet datasets. The workloads are vendor-optimized for each architecture. We use sequentially equivalent implementations to maintain iso-accuracy between parallel and sequential DL models. Our analysis indicates that although GPUs provide the highest overall performance, the gap can close for some convolutional networks; and the KNL can be competitive in performance/watt. We find that NVLink facilitates scaling efficiency on GPUs. However, its importance is heavily dependent on neural network architecture. Furthermore, for weak-scaling—sometimes encouraged by restricted GPU memory—NVLink is less important.« less
Szilágyi, András; Zachar, István; Szathmáry, Eörs
2013-01-01
Models of competitive template replication, although basic for replicator dynamics and primordial evolution, have not yet taken different sequences explicitly into account, neither have they analyzed the effect of resource partitioning (feeding on different resources) on coexistence. Here we show by analytical and numerical calculations that Gause's principle of competitive exclusion holds for template replicators if resources (nucleotides) affect growth linearly and coexistence is at fixed point attractors. Cases of complementary or homologous pairing between building blocks with parallel or antiparallel strands show no deviation from the rule that the nucleotide compositions of stably coexisting species must be different and there cannot be more coexisting replicator species than nucleotide types. Besides this overlooked mechanism of template coexistence we show also that interesting sequence effects prevail as parts of sequences that are copied earlier affect coexistence more strongly due to the higher concentration of the corresponding replication intermediates. Template and copy always count as one species due their constraint of strict stoichiometric coupling. Stability of fixed-point coexistence tends to decrease with the length of sequences, although this effect is unlikely to be detrimental for sequences below 100 nucleotides. In sum, resource partitioning (niche differentiation) is the default form of competitive coexistence for replicating templates feeding on a cocktail of different nucleotides, as it may have been the case in the RNA world. Our analysis of different pairing and strand orientation schemes is relevant for artificial and potentially astrobiological genetics. PMID:23990769
USDA-ARS?s Scientific Manuscript database
Wild squash bees have all five traits ascribed to the most effective crop pollinators. They are abundant, competitive, efficient, faithful to a specific crop and fast. Shared pollinator surveys covering 2,700 ha of US squash and pumpkin (n = 50 farms) show strong parallels among Cucurbita’s bee gui...
ERIC Educational Resources Information Center
Chambers, Craig G.; Cooke, Hilary
2009-01-01
A spoken language eye-tracking methodology was used to evaluate the effects of sentence context and proficiency on parallel language activation during spoken language comprehension. Nonnative speakers with varying proficiency levels viewed visual displays while listening to French sentences (e.g., "Marie va decrire la poule" [Marie will…
Performance Analysis of Multilevel Parallel Applications on Shared Memory Architectures
NASA Technical Reports Server (NTRS)
Biegel, Bryan A. (Technical Monitor); Jost, G.; Jin, H.; Labarta J.; Gimenez, J.; Caubet, J.
2003-01-01
Parallel programming paradigms include process level parallelism, thread level parallelization, and multilevel parallelism. This viewgraph presentation describes a detailed performance analysis of these paradigms for Shared Memory Architecture (SMA). This analysis uses the Paraver Performance Analysis System. The presentation includes diagrams of a flow of useful computations.
NASA Technical Reports Server (NTRS)
Smith, Garrett; Philips, Alan
2003-01-01
Three dominant Two Stage To Orbit (TSTO) class architectures were studied: Series Burn (SB), Parallel Bum with crossfeed (PBw/cf), and Parallel Burn, no-crossfeed (PBncf). The study goal was to determine what factors uniquely affect PBncf architectures, how each of these factors interact, and to determine from a performance perspective whether a PBncf vehicle could be competitive with a PBw/cf or a SB vehicle using equivalent technology and assumptions. In all cases, performance was evaluated on a relative basis for a fixed payload and mission by comparing gross and dry vehicle masses of a closed vehicle. Propellant combinations studied were LOX: LH2 propelled booster and orbiter (HH) and LOX: Kerosene booster with LOX: LH2 orbiter (KH). The study observations were: 1) A PBncf orbiter should be throttled as deeply as possible after launch until the staging point. 2) A PBncf TSTO architecture is feasible for systems that stage at mach 7. 2a) HH architectures can achieve a mass growth relative to PBw/cf of <20%. 2b) KH architectures can achieve a mass growth relative to Series Burn of <20%. 3) Center of gravity (CG) control will be a major issue for a PBncf vehicle, due to the low orbiter specific thrust to weight ratio and to the position of the orbiter required to align the nozzle heights at liftoff. 4) Thrust to weight ratios of 1.3 at liftoff and between 1.0 and 0.9 when staging at mach 7 appear to be close to ideal for PBncf vehicles. 5) Performance for HH vehicles was better when staged at mach 7 instead of mach 5. The study suggests possible methods to maximize performance of PBncf vehicle architectures in order to meet mission design requirements.
Boguta, Patrycja; Pieczywek, Piotr M.; Sokołowska, Zofia
2016-01-01
The main aim of this study was the application of excitation-emission fluorescence matrices (EEMs) combined with two decomposition methods: parallel factor analysis (PARAFAC) and nonnegative matrix factorization (NMF) to study the interaction mechanisms between humic acids (HAs) and Zn(II) over a wide concentration range (0–50 mg·dm−3). The influence of HA properties on Zn(II) complexation was also investigated. Stability constants, quenching degree and complexation capacity were estimated for binding sites found in raw EEM, EEM-PARAFAC and EEM-NMF data using mathematical models. A combination of EEM fluorescence analysis with one of the proposed decomposition methods enabled separation of overlapping binding sites and yielded more accurate calculations of the binding parameters. PARAFAC and NMF processing allowed finding binding sites invisible in a few raw EEM datasets as well as finding totally new maxima attributed to structures of the lowest humification. Decomposed data showed an increase in Zn complexation with an increase in humification, aromaticity and molecular weight of HAs. EEM-PARAFAC analysis also revealed that the most stable compounds were formed by structures containing the highest amounts of nitrogen. The content of oxygen-functional groups did not influence the binding parameters, mainly due to fact of higher competition of metal cation with protons. EEM spectra coupled with NMF and especially PARAFAC processing gave more adequate assessments of interactions as compared to raw EEM data and should be especially recommended for modeling of complexation processes where the fluorescence intensities (FI) changes are weak or where the processes are interfered with by the presence of other fluorophores. PMID:27782078
Parallel pathways of potassium transport in the alga Hydrodictyon reticulatum. Effects of calcium.
Nespůrková, L; Rybová, R; Janácek, K
1987-06-01
Inflow of potassium ions into the alga Hydrodictyon reticulatum is reduced in the dark, the reduction being accompanied by a change in the selectivity pattern with respect to alkali metal ions, observed in competition experiments and evaluated by the gnostic analysis as described by Kovanic. This suggests that in the light a special mechanism of potassium uptake with a characteristic selectivity is switched on. This mechanism can be also suppressed by too high (2 mmol/l) or too low (EGTA) concentration of calcium ions in the medium. Since the same applies to the light-induced alkalinization of the algal surroundings it seems that the light-induced potassium uptake is related to the light-induced alkalinization, e.g., via exchange of external potassium cations for intracellular protons.
Spatial data analytics on heterogeneous multi- and many-core parallel architectures using python
Laura, Jason R.; Rey, Sergio J.
2017-01-01
Parallel vector spatial analysis concerns the application of parallel computational methods to facilitate vector-based spatial analysis. The history of parallel computation in spatial analysis is reviewed, and this work is placed into the broader context of high-performance computing (HPC) and parallelization research. The rise of cyber infrastructure and its manifestation in spatial analysis as CyberGIScience is seen as a main driver of renewed interest in parallel computation in the spatial sciences. Key problems in spatial analysis that have been the focus of parallel computing are covered. Chief among these are spatial optimization problems, computational geometric problems including polygonization and spatial contiguity detection, the use of Monte Carlo Markov chain simulation in spatial statistics, and parallel implementations of spatial econometric methods. Future directions for research on parallelization in computational spatial analysis are outlined.
Serial vs. parallel models of attention in visual search: accounting for benchmark RT-distributions.
Moran, Rani; Zehetleitner, Michael; Liesefeld, Heinrich René; Müller, Hermann J; Usher, Marius
2016-10-01
Visual search is central to the investigation of selective visual attention. Classical theories propose that items are identified by serially deploying focal attention to their locations. While this accounts for set-size effects over a continuum of task difficulties, it has been suggested that parallel models can account for such effects equally well. We compared the serial Competitive Guided Search model with a parallel model in their ability to account for RT distributions and error rates from a large visual search data-set featuring three classical search tasks: 1) a spatial configuration search (2 vs. 5); 2) a feature-conjunction search; and 3) a unique feature search (Wolfe, Palmer & Horowitz Vision Research, 50(14), 1304-1311, 2010). In the parallel model, each item is represented by a diffusion to two boundaries (target-present/absent); the search corresponds to a parallel race between these diffusors. The parallel model was highly flexible in that it allowed both for a parametric range of capacity-limitation and for set-size adjustments of identification boundaries. Furthermore, a quit unit allowed for a continuum of search-quitting policies when the target is not found, with "single-item inspection" and exhaustive searches comprising its extremes. The serial model was found to be superior to the parallel model, even before penalizing the parallel model for its increased complexity. We discuss the implications of the results and the need for future studies to resolve the debate.
Topology-dependent density optima for efficient simultaneous network exploration
NASA Astrophysics Data System (ADS)
Wilson, Daniel B.; Baker, Ruth E.; Woodhouse, Francis G.
2018-06-01
A random search process in a networked environment is governed by the time it takes to visit every node, termed the cover time. Often, a networked process does not proceed in isolation but competes with many instances of itself within the same environment. A key unanswered question is how to optimize this process: How many concurrent searchers can a topology support before the benefits of parallelism are outweighed by competition for space? Here, we introduce the searcher-averaged parallel cover time (APCT) to quantify these economies of scale. We show that the APCT of the networked symmetric exclusion process is optimized at a searcher density that is well predicted by the spectral gap. Furthermore, we find that nonequilibrium processes, realized through the addition of bias, can support significantly increased density optima. Our results suggest alternative hybrid strategies of serial and parallel search for efficient information gathering in social interaction and biological transport networks.
Parallel NGO networks for HIV control: risks and opportunities for NGO contracting.
Zaidi, Shehla; Gul, Xaher; Nishtar, Noureen Aleem
2012-12-27
Policy measures for preventive and promotive services are increasingly reliant on contracting of NGOs. Contracting is a neo-liberal response relying on open market competition for service delivery tenders. In contracting of health services a common assumption is a monolithic NGO market. A case study of HIV control in Pakistan shows that in reality the NGO market comprises of parallel NGO networks having widely different service packages, approaches and agendas. These parallel networks had evolved over time due to vertical policy agendas. Contracting of NGOs for provision of HIV services was faced with uneven capacities and turf rivalries across both NGO networks. At the same time contracting helped NGO providers belonging to different clusters to move towards standardized service delivery for HIV prevention. Market based measures such as contracting need to be accompanied with wider policy measures that facilitate in bringing NGOs groups to a shared understanding of health issues and responses.
Non-elliptic wavevector anisotropy for magnetohydrodynamic turbulence
NASA Astrophysics Data System (ADS)
Narita, Y.
2015-11-01
A model of non-elliptic wavevector anisotropy is developed for the inertial-range spectrum of magnetohydrodynamic turbulence and is presented in the two-dimensional wavevector domain spanning the directions parallel and perpendicular to the mean magnetic field. The non-elliptic model is a variation of the elliptic model with different scalings along the parallel and the perpendicular components of the wavevectors to the mean magnetic field. The non-elliptic anisotropy model reproduces the smooth transition of the power-law spectra from an index of -2 in the parallel projection with respect to the mean magnetic field to an index of -5/3 in the perpendicular projection observed in solar wind turbulence, and is as competitive as the critical balance model to explain the measured frequency spectra in the solar wind. The parameters in the non-elliptic spectrum model are compared with the solar wind observations.
Distributed process manager for an engineering network computer
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gait, J.
1987-08-01
MP is a manager for systems of cooperating processes in a local area network of engineering workstations. MP supports transparent continuation by maintaining multiple copies of each process on different workstations. Computational bandwidth is optimized by executing processes in parallel on different workstations. Responsiveness is high because workstations compete among themselves to respond to requests. The technique is to select a master from among a set of replicates of a process by a competitive election between the copies. Migration of the master when a fault occurs or when response slows down is effected by inducing the election of a newmore » master. Competitive response stabilizes system behavior under load, so MP exhibits realtime behaviors.« less
Computational Modeling of the Dolphin Kick in Competitive Swimming
NASA Astrophysics Data System (ADS)
Loebbeck, A.; Mark, R.; Bhanot, G.
2005-11-01
Numerical simulations are being used to study the fluid dynamics of the dolphin kick in competitive swimming. This stroke is performed underwater after starts and turns and involves an undulatory motion of the body. Highly detailed laser body scans of elite swimmers are used and the kinematics of the dolphin kick is recreated from videos of Olympic level swimmers. We employ a parallelized immersed boundary method to simulate the flow associated with this stroke in all its complexity. The simulations provide a first of its kind glimpse of the fluid and vortex dynamics associated with this stroke and hydrodynamic force computations allow us to gain a better understanding of the thrust producing mechanisms.
The Secret History of Proprietary Legal Education: The Case of the Houston Law School, 1919-1945.
ERIC Educational Resources Information Center
Steiner, Mark E.
1997-01-01
Examines the history of the Houston Law School (Texas), a part-time night school that operated from 1919-1945 and was part of a brief period of ascendence for proprietary law schools. Discusses its competition with another institution, shifts in standards and enrollments, and other factors leading to its decline. Notes parallels between this…
Competitive hybridization models
NASA Astrophysics Data System (ADS)
Cherepinsky, Vera; Hashmi, Ghazala; Mishra, Bud
2010-11-01
Microarray technology, in its simplest form, allows one to gather abundance data for target DNA molecules, associated with genomes or gene-expressions, and relies on hybridizing the target to many short probe oligonucleotides arrayed on a surface. While for such multiplexed reactions conditions are optimized to make the most of each individual probe-target interaction, subsequent analysis of these experiments is based on the implicit assumption that a given experiment yields the same result regardless of whether it was conducted in isolation or in parallel with many others. It has been discussed in the literature that this assumption is frequently false, and its validity depends on the types of probes and their interactions with each other. We present a detailed physical model of hybridization as a means of understanding probe interactions in a multiplexed reaction. Ultimately, the model can be derived from a system of ordinary differential equations (ODE’s) describing kinetic mass action with conservation-of-mass equations completing the system. We examine pairwise probe interactions in detail and present a model of “competition” between the probes for the target—especially, when the target is effectively in short supply. These effects are shown to be predictable from the affinity constants for each of the four probe sequences involved, namely, the match and mismatch sequences for both probes. These affinity constants are calculated from the thermodynamic parameters such as the free energy of hybridization, which are in turn computed according to the nearest neighbor (NN) model for each probe and target sequence. Simulations based on the competitive hybridization model explain the observed variability in the signal of a given probe when measured in parallel with different groupings of other probes or individually. The results of the simulations can be used for experiment design and pooling strategies, based on which probes have been shown to have a strong effect on each other’s signal in the in silico experiment. These results are aimed at better design of multiplexed reactions on arrays used in genotyping (e.g., HLA typing, SNP, or CNV detection, etc.) and mutation analysis (e.g., cystic fibrosis, cancer, autism, etc.).
Task-Relevant Information Modulates Primary Motor Cortex Activity Before Movement Onset.
Calderon, Cristian B; Van Opstal, Filip; Peigneux, Philippe; Verguts, Tom; Gevers, Wim
2018-01-01
Monkey neurophysiology research supports the affordance competition hypothesis (ACH) proposing that cognitive information useful for action selection is integrated in sensorimotor areas. In this view, action selection would emerge from the simultaneous representation of competing action plans, in parallel biased by relevant task factors. This biased competition would take place up to primary motor cortex (M1). Although ACH is plausible in environments affording choices between actions, its relevance for human decision making is less clear. To address this issue, we designed an functional magnetic resonance imaging (fMRI) experiment modeled after monkey neurophysiology studies in which human participants processed cues conveying predictive information about upcoming button presses. Our results demonstrate that, as predicted by the ACH, predictive information (i.e., the relevant task factor) biases activity of primary motor regions. Specifically, first, activity before movement onset in contralateral M1 increases as the competition is biased in favor of a specific button press relative to activity in ipsilateral M1. Second, motor regions were more tightly coupled with fronto-parietal regions when competition between potential actions was high, again suggesting that motor regions are also part of the biased competition network. Our findings support the idea that action planning dynamics as proposed in the ACH are valid both in human and non-human primates.
Product competitiveness analysis for e-commerce platform of special agricultural products
NASA Astrophysics Data System (ADS)
Wan, Fucheng; Ma, Ning; Yang, Dongwei; Xiong, Zhangyuan
2017-09-01
On the basis of analyzing the influence factors of the product competitiveness of the e-commerce platform of the special agricultural products and the characteristics of the analytical methods for the competitiveness of the special agricultural products, the price, the sales volume, the postage included service, the store reputation, the popularity, etc. were selected in this paper as the dimensionality for analyzing the competitiveness of the agricultural products, and the principal component factor analysis was taken as the competitiveness analysis method. Specifically, the web crawler was adopted to capture the information of various special agricultural products in the e-commerce platform ---- chi.taobao.com. Then, the original data captured thereby were preprocessed and MYSQL database was adopted to establish the information library for the special agricultural products. Then, the principal component factor analysis method was adopted to establish the analysis model for the competitiveness of the special agricultural products, and SPSS was adopted in the principal component factor analysis process to obtain the competitiveness evaluation factor system (support degree factor, price factor, service factor and evaluation factor) of the special agricultural products. Then, the linear regression method was adopted to establish the competitiveness index equation of the special agricultural products for estimating the competitiveness of the special agricultural products.
Ergonomic analyses of downhill skiing.
Clarys, J P; Publie, J; Zinzen, E
1994-06-01
The purpose of this study was to provide electromyographic feedback for (1) pedagogical advice in motor learning, (2) the ergonomics of materials choice and (3) competition. For these purposes: (1) EMG data were collected for the Stem Christie, the Stem Turn and the Parallel Christie (three basic ski initiation drills) and verified for the complexity of patterns; (2) integrated EMG (iEMG) and linear envelopes (LEs) were analysed from standardized positions, motions and slopes using compact, soft and competition skis; (3) in a simulated 'parallel special slalom', the muscular activity pattern and intensity of excavated and flat snow conditions were compared. The EMG data from the three studies were collected on location in the French Alps (Tignes). The analog raw EMG was recorded on the slopes with a portable seven-channel FM recorder (TEAC MR30) and with pre-amplified bipolar surface electrodes supplied with a precision instrumentation amplifier (AD 524, Analog Devices, Norwood, USA). The raw signal was full-wave rectified and enveloped using a moving average principle. This linear envelope was normalized according to the highest peak amplitude procedure per subject and was integrated in order to obtain a reference of muscular intensity. In the three studies and for all subjects (elite skiers: n = 25 in studies 1 and 2, n = 6 in study 3), we found a high level of co-contractions in the lower limb extensors and flexors, especially during the extension phase of the ski movement. The Stem Christie and the Parallel Christie showed higher levels of rhythmic movement (92 and 84%, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
A study on optimization of hybrid drive train using Advanced Vehicle Simulator (ADVISOR)
NASA Astrophysics Data System (ADS)
Same, Adam; Stipe, Alex; Grossman, David; Park, Jae Wan
This study investigates the advantages and disadvantages of three hybrid drive train configurations: series, parallel, and "through-the-ground" parallel. Power flow simulations are conducted with the MATLAB/Simulink-based software ADVISOR. These simulations are then applied in an application for the UC Davis SAE Formula Hybrid vehicle. ADVISOR performs simulation calculations for vehicle position using a combined backward/forward method. These simulations are used to study how efficiency and agility are affected by the motor, fuel converter, and hybrid configuration. Three different vehicle models are developed to optimize the drive train of a vehicle for three stages of the SAE Formula Hybrid competition: autocross, endurance, and acceleration. Input cycles are created based on rough estimates of track geometry. The output from these ADVISOR simulations is a series of plots of velocity profile and energy storage State of Charge that provide a good estimate of how the Formula Hybrid vehicle will perform on the given course. The most noticeable discrepancy between the input cycle and the actual velocity profile of the vehicle occurs during deceleration. A weighted ranking system is developed to organize the simulation results and to determine the best drive train configuration for the Formula Hybrid vehicle. Results show that the through-the-ground parallel configuration with front-mounted motors achieves an optimal balance of efficiency, simplicity, and cost. ADVISOR is proven to be a useful tool for vehicle power train design for the SAE Formula Hybrid competition. This vehicle model based on ADVISOR simulation is applicable to various studies concerning performance and efficiency of hybrid drive trains.
Parallel algorithms for large-scale biological sequence alignment on Xeon-Phi based clusters.
Lan, Haidong; Chan, Yuandong; Xu, Kai; Schmidt, Bertil; Peng, Shaoliang; Liu, Weiguo
2016-07-19
Computing alignments between two or more sequences are common operations frequently performed in computational molecular biology. The continuing growth of biological sequence databases establishes the need for their efficient parallel implementation on modern accelerators. This paper presents new approaches to high performance biological sequence database scanning with the Smith-Waterman algorithm and the first stage of progressive multiple sequence alignment based on the ClustalW heuristic on a Xeon Phi-based compute cluster. Our approach uses a three-level parallelization scheme to take full advantage of the compute power available on this type of architecture; i.e. cluster-level data parallelism, thread-level coarse-grained parallelism, and vector-level fine-grained parallelism. Furthermore, we re-organize the sequence datasets and use Xeon Phi shuffle operations to improve I/O efficiency. Evaluations show that our method achieves a peak overall performance up to 220 GCUPS for scanning real protein sequence databanks on a single node consisting of two Intel E5-2620 CPUs and two Intel Xeon Phi 7110P cards. It also exhibits good scalability in terms of sequence length and size, and number of compute nodes for both database scanning and multiple sequence alignment. Furthermore, the achieved performance is highly competitive in comparison to optimized Xeon Phi and GPU implementations. Our implementation is available at https://github.com/turbo0628/LSDBS-mpi .
ERIC Educational Resources Information Center
Stamm, Meelis; Stamm, Raini; Koskel, Sade
2008-01-01
Study aim: Assessment of feasibility of using own computer software "Game" at competitions. Material and methods: The data were collected during Estonian championships in 2006 for male volleyball teams of the 13-15-years age group (n = 8). In all games, the performance of both teams was recorded in parallel with two computers. A total of…
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1997-08-01
The emergence of competitive markets for electricity generation services is changing the way that electricity is and will be priced in the United States. This report presents the results of an analysis that focuses on two questions: (1) How are prices for competitive generation services likely to differ from regulated prices if competitive prices are based on marginal costs rather than regulated {open_quotes}cost-of-service{close_quotes} pricing? (2) What impacts will the competitive pricing of generation services (based on marginal costs) have on electricity consumption patterns, production costs, and the financial integrity patterns, production costs, and the financial integrity of electricity suppliers? Thismore » study is not intended to be a cost-benefit analysis of wholesale or retail competition, nor does this report include an analysis of the macroeconomic impacts of competitive electricity prices.« less
Analysis of the JSF Engine Competition
2012-09-01
even 25 Competition for Support Services Support costs are typically more than half of life-cycle costs and normally incurred in a sole-source...Strike Fighter), Aircraft Engines, Competition, Military Procurement, Defense Industry, Cost Analysis Analysis of the JSF Engine Competition James...different designs to meet the same functional requirements. Such a case was examined by the Institute for Defense Analyses in a forward-looking cost and
Nishiguchi, Michele K.; Ruby, Edward G.; McFall-Ngai, Margaret J.
1998-01-01
One of the principal assumptions in symbiosis research is that associated partners have evolved in parallel. We report here experimental evidence for parallel speciation patterns among several partners of the sepiolid squid-luminous bacterial symbioses. Molecular phylogenies for 14 species of host squids were derived from sequences of both the nuclear internal transcribed spacer region and the mitochondrial cytochrome oxidase subunit I; the glyceraldehyde phosphate dehydrogenase locus was sequenced for phylogenetic determinations of 7 strains of bacterial symbionts. Comparisons of trees constructed for each of the three loci revealed a parallel phylogeny between the sepiolids and their respective symbionts. Because both the squids and their bacterial partners can be easily cultured independently in the laboratory, we were able to couple these phylogenetic analyses with experiments to examine the ability of the different symbiont strains to compete with each other during the colonization of one of the host species. Our results not only indicate a pronounced dominance of native symbiont strains over nonnative strains, but also reveal a hierarchy of symbiont competency that reflects the phylogenetic relationships of the partners. For the first time, molecular systematics has been coupled with experimental colonization assays to provide evidence for the existence of parallel speciation among a set of animal-bacterial associations. PMID:9726861
WFIRST: Science from the Guest Investigator and Parallel Observation Programs
NASA Astrophysics Data System (ADS)
Postman, Marc; Nataf, David; Furlanetto, Steve; Milam, Stephanie; Robertson, Brant; Williams, Ben; Teplitz, Harry; Moustakas, Leonidas; Geha, Marla; Gilbert, Karoline; Dickinson, Mark; Scolnic, Daniel; Ravindranath, Swara; Strolger, Louis; Peek, Joshua; Marc Postman
2018-01-01
The Wide Field InfraRed Survey Telescope (WFIRST) mission will provide an extremely rich archival dataset that will enable a broad range of scientific investigations beyond the initial objectives of the proposed key survey programs. The scientific impact of WFIRST will thus be significantly expanded by a robust Guest Investigator (GI) archival research program. We will present examples of GI research opportunities ranging from studies of the properties of a variety of Solar System objects, surveys of the outer Milky Way halo, comprehensive studies of cluster galaxies, to unique and new constraints on the epoch of cosmic re-ionization and the assembly of galaxies in the early universe.WFIRST will also support the acquisition of deep wide-field imaging and slitless spectroscopic data obtained in parallel during campaigns with the coronagraphic instrument (CGI). These parallel wide-field imager (WFI) datasets can provide deep imaging data covering several square degrees at no impact to the scheduling of the CGI program. A competitively selected program of well-designed parallel WFI observation programs will, like the GI science above, maximize the overall scientific impact of WFIRST. We will give two examples of parallel observations that could be conducted during a proposed CGI program centered on a dozen nearby stars.
Sugden, E A; Stilwell, K; Rohonczy, E B; Martineau, P
1997-01-01
A competitive enzyme-linked immunosorbent assay (C-ELISA) using M. bovis BCG Tokyo culture filtrate as antigen and anti-MPB70 4C3/17 monoclonal antibody was developed for use in multiple animal species. An analysis of the C-ELISA data for cattle and bison serum panels revealed specificities of 68% to 85% and sensitivities of 85% to 89%. Receiver operator characteristics (ROC) of this data revealed areas of 81% to 92% for C-ELISA and demonstrated that C-ELISA as well as the indirect ELISA protocols, MPB70-ELISA and LAM-ELISA, discriminate M. bovis infected animals from non-infected animals for these particular panels. The kappa statistic values for agreement beyond chance between C-ELISA and MPB70-ELISA were determined after ELISA cutoffs were adjusted to minimize false positives. There were poor to excellent agreements between C-ELISA and MPB70-ELISA in all species tested (Bovidae, Cervidae, and Camelidae) that were consistently higher than the kappa statistic between C-ELISA and LAM-ELISA. The humoral response to one antigen and little or no response to the other in many animals argued for a parallel interpretation of C-ELISA and LAM-ELISA to increase sensitivity. PMID:9008794
Interactions of agonists with an allosteric antagonist at muscarinic acetylcholine M2 receptors.
Lanzafame, A; Christopoulos, A; Mitchelson, F
1996-11-28
The interaction of heptane-1,7-bis(dimethyl-3'-phthalimidopropylammonium bromide) (C7/3'-phth), with several agonists, was investigated at the muscarinic M2 receptor in guinea-pig left atria. C7/3'-phth shifted concentration-response curves for the agonists, carbachol, oxotremorine-M and (+)-cis-dioxolane, to the right in a parallel fashion. Arunlakshana-Schild regressions of the data yielded slopes significantly different to unity, suggesting non-competitive antagonism. Non-linear regression analysis, using an equation based on allosteric modulation, gave quantitative estimates of co-operativity (alpha values) and the dissociation constant of C7/3'-phth (KB). In all cases, the KB estimates for C7/3'-phth were not significantly different. Increasing the carbachol contact time 10-fold did not significantly influence the KB or the alpha value obtained with C7/3'-phth. Changing from Krebs to Tyrode solution did not significantly alter the KB for C7/3'-phth, although alpha values obtained were consistently lower in Tyrode solution, suggesting that the allosteric action may be sensitive to buffer composition. A 4-fold higher degree of negative, heterotropic co-operativity between C7/3'-phth and agonists than between C7/3'-phth and competitive antagonists was also found.
Language Learning and Control in Monolinguals and Bilinguals
Bartolotti, James; Marian, Viorica
2012-01-01
Parallel language activation in bilinguals leads to competition between languages. Experience managing this interference may aid novel language learning by improving the ability to suppress competition from known languages. To investigate the effect of bilingualism on the ability to control native-language interference, monolinguals and bilinguals were taught an artificial language designed to elicit between-language competition. Partial activation of interlingual competitors was assessed with eye-tracking and mouse-tracking during a word recognition task in the novel language. Eye-tracking results showed that monolinguals looked at competitors more than bilinguals, and for a longer duration of time. Mouse-tracking results showed that monolinguals’ mouse-movements were attracted to native-language competitors, while bilinguals overcame competitor interference by increasing activation of target items. Results suggest that bilinguals manage cross-linguistic interference more effectively than monolinguals. We conclude that language interference can affect lexical retrieval, but bilingualism may reduce this interference by facilitating access to a newly-learned language. PMID:22462514
NASA Astrophysics Data System (ADS)
Wang, Hai-Feng; Lin, Zhen-Quan; Gao, Yan; Zhang, Heng
2009-10-01
A competition model of three species in exchange-driven aggregation growth is proposed. In the model, three distinct aggregates grow by exchange of monomers and in parallel, birth of species A is catalyzed by species B and death of species A is catalyzed by species C. The rates for both catalysis processes are proportional to kjν and kjω respectively, where ν(Ω) is a parameter reflecting the dependence of the catalysis reaction rate of birth (death) on the catalyst aggregate's size. The kinetic evolution behaviors of the three species are investigated by the rate equation approach based on the mean-field theory. The form of the aggregate size distribution of A-species ak(t) is found to be dependent crucially on the two catalysis rate kernel parameters. The results show that (i) in case of μ <= 0, the form of ak(t) mainly depends on the competition between self-exchange of species A and species-C-catalyzed death of species A; (ii) in case of ν > 0, the form of ak(t) mainly depends on the competition between species-B-catalyzed birth of species A and species-C-catalyzed death of species A.
Engineering Analysis in the Chem-E-Car Competition
ERIC Educational Resources Information Center
Lewis, Randy S.; Moshfeghian, Aliakbar; Madihally, Sundararajan V.
2006-01-01
The AIChE Chem-E-Car competition provides students an opportunity to demonstrate their design and teamwork skills. Engineering analysis is not required at the national competition and is often not applied. This work describes an engineering analysis of a Chem-E-Car to predict the distance traveled by the car. Engineering analysis is advantageous…
Smith, S. Abigail; Wood, Charles; West, John T.
2013-01-01
Human immunodeficiency virus type-1 (HIV-1) fitness has been associated with virus entry, a process mediated by the envelope glycoprotein (Env). We previously described Env genetic diversification in a Zambian, subtype C infected, slow-progressor child (1157i) in parallel with an evolving neutralizing antibody response. Because of the role the Variable-3 loop (V3) plays in transmission, cell tropism, neutralization sensitivity, and fitness, longitudinally isolated 1157i C2-V4 alleles were cloned into HIV-1NL4-3-eGFP and -DsRed2 infectious molecular clones. The fluorescent reporters allowed for dual-infection competitions between all patient-derived C2-V4 chimeras to quantify the effect of V3 diversification and selection on fitness. ‘Winners’ and ‘losers’ were readily discriminated among the C2-V4 alleles. Exceptional sensitivity for detection of subtle fitness differences was revealed through analysis of two alleles differing in a single synonymous amino acid. However, when the outcomes of N = 33 competitions were averaged for each chimera, the aggregate analysis showed that despite increasing diversification and divergence with time, natural selection of C2-V4 sequences in this individual did not appear to be producing a ‘survival of the fittest’ evolutionary pattern. Rather, we detected a relatively flat fitness landscape consistent with mutational robustness. Fitness outcomes were then correlated with individual components of the entry process. Env incorporation into particles correlated best with fitness, suggesting a role for Env avidity, as opposed to receptor/coreceptor affinity, in defining fitness. Nevertheless, biochemical analyses did not identify any step in HIV-1 entry as a dominant determinant of fitness. Our results lead us to conclude that multiple aspects of entry contribute to maintaining adequate HIV-1 fitness, and there is no surrogate analysis for determining fitness. The capacity for subtle polymorphisms in Env to nevertheless significantly impact viral fitness suggests fitness is best defined by head-to-head competition. PMID:23638182
Quality health care in the European Union thanks to competition law.
Fornaciari, Diego
2010-01-01
There are many biases concerning the application of competition law in health care. Quality concerns can however be integrated into competition law analysis. The aim of this paper is to identify the links between the application of competition law in the European Union and the right to quality health care and to point out the problems that arise when integrating quality concerns in competition law analysis. Guidelines must be issued and competition authorities must work together with institutions that have expertise in the field of health care quality measurement in order to integrate these dimensions in competition practice.
Parallel NGO Networks for HIV Control: Risks and Opportunities for NGO Contracting
Zaidi, Shehla; Gul, Xaher; Nishtar, Noureen
2013-01-01
Policy measures for preventive and promotive services are increasingly reliant on contracting of NGOs. Contracting is a neo-liberal response relying on open market competition for service delivery tenders. In contracting of health services a common assumption is a monolithic NGO market. A case study of HIV control in Pakistan shows that in reality the NGO market comprises of parallel NGO networks having widely different service packages, approaches and agendas. These parallel networks had evolved over time due to vertical policy agendas. Contracting of NGOs for provision of HIV services was faced with uneven capacities and turf rivalries across both NGO networks. At the same time contracting helped NGO providers belonging to different clusters to move towards standardized service delivery for HIV prevention. Market based measures such as contracting need to be accompanied with wider policy and system measures that overcome silos in NGO working by facilitating a common construct on the health issue, cohesive priorities and integrated working. PMID:23445705
Parallel Navier-Stokes computations on shared and distributed memory architectures
NASA Technical Reports Server (NTRS)
Hayder, M. Ehtesham; Jayasimha, D. N.; Pillay, Sasi Kumar
1995-01-01
We study a high order finite difference scheme to solve the time accurate flow field of a jet using the compressible Navier-Stokes equations. As part of our ongoing efforts, we have implemented our numerical model on three parallel computing platforms to study the computational, communication, and scalability characteristics. The platforms chosen for this study are a cluster of workstations connected through fast networks (the LACE experimental testbed at NASA Lewis), a shared memory multiprocessor (the Cray YMP), and a distributed memory multiprocessor (the IBM SPI). Our focus in this study is on the LACE testbed. We present some results for the Cray YMP and the IBM SP1 mainly for comparison purposes. On the LACE testbed, we study: (1) the communication characteristics of Ethernet, FDDI, and the ALLNODE networks and (2) the overheads induced by the PVM message passing library used for parallelizing the application. We demonstrate that clustering of workstations is effective and has the potential to be computationally competitive with supercomputers at a fraction of the cost.
Reliability analysis and initial requirements for FC systems and stacks
NASA Astrophysics Data System (ADS)
Åström, K.; Fontell, E.; Virtanen, S.
In the year 2000 Wärtsilä Corporation started an R&D program to develop SOFC systems for CHP applications. The program aims to bring to the market highly efficient, clean and cost competitive fuel cell systems with rated power output in the range of 50-250 kW for distributed generation and marine applications. In the program Wärtsilä focuses on system integration and development. System reliability and availability are key issues determining the competitiveness of the SOFC technology. In Wärtsilä, methods have been implemented for analysing the system in respect to reliability and safety as well as for defining reliability requirements for system components. A fault tree representation is used as the basis for reliability prediction analysis. A dynamic simulation technique has been developed to allow for non-static properties in the fault tree logic modelling. Special emphasis has been placed on reliability analysis of the fuel cell stacks in the system. A method for assessing reliability and critical failure predictability requirements for fuel cell stacks in a system consisting of several stacks has been developed. The method is based on a qualitative model of the stack configuration where each stack can be in a functional, partially failed or critically failed state, each of the states having different failure rates and effects on the system behaviour. The main purpose of the method is to understand the effect of stack reliability, critical failure predictability and operating strategy on the system reliability and availability. An example configuration, consisting of 5 × 5 stacks (series of 5 sets of 5 parallel stacks) is analysed in respect to stack reliability requirements as a function of predictability of critical failures and Weibull shape factor of failure rate distributions.
Minucci, Angelo; De Paolis, Elisa; Concolino, Paola; De Bonis, Maria; Rizza, Roberta; Canu, Giulia; Scaglione, Giovanni Luca; Mignone, Flavio; Scambia, Giovanni; Zuppi, Cecilia; Capoluongo, Ettore
2017-07-01
Evaluation of copy number variation (CNV) in BRCA1/2 genes, due to large genomic rearrangements (LGRs), is a mandatory analysis in hereditary breast and ovarian cancers families, if no pathogenic variants are found by sequencing. LGRs cannot be detected by conventional methods and several alternative methods have been developed. Since these approaches are expensive and time consuming, identification of alternative screening methods for LGRs detection is needed in order to reduce and optimize the diagnostic procedure. The aim of this study was to investigate a Competitive PCR-High Resolution Melting Analysis (C-PCR-HRMA) as molecular tool to detect recurrent BRCA1 LGRs. C-PCR-HRMA was performed on exons 3, 14, 18, 19, 20 and 21 of the BRCA1 gene; exons 4, 6 and 7 of the ALB gene were used as reference fragments. This study showed that it is possible to identify recurrent BRCA1 LGRs, by melting peak height ratio between target (BRCA1) and reference (ALB) fragments. Furthermore, we underline that a peculiar amplicon-melting profile is associated to a specific BRCA1 LGR. All C-PCR-HRMA results were confirmed by Multiplex ligation-dependent probe amplification. C-PCR-HRMA has proved to be an innovative, efficient and fast method for BRCA1 LGRs detection. Given the sensitivity, specificity and ease of use, c-PCR-HRMA can be considered an attractive and powerful alternative to other methods for BRCA1 CNVs screening, improving molecular strategies for BRCA testing in the context of Massive Parallel Sequencing. Copyright © 2017 Elsevier B.V. All rights reserved.
USDA-ARS?s Scientific Manuscript database
Rill networks have been a focus of study for many decades but we still lack a complete understanding of what variables control the spacing of rills and the geometry of rill networks (e.g. parallel or dendritic) on hillslopes. In this paper we investigate the controls on the spacing and geometry of ...
Experimental Program to Stimulate Competitive Research (EPSCoR)
NASA Technical Reports Server (NTRS)
Dingerson, Michael R.
1997-01-01
Report includes: (1) CLUSTER: "Studies in Macromolecular Behavior in Microgravity Environment": The Role of Protein Oligomers in Protein Crystallization; Phase Separation Phenomena in Microgravity; Traveling Front Polymerizations; Investigating Mechanisms Affecting Phase Transition Response and Changes in Thermal Transport Properties in ER-Fluids under Normal and Microgravity Conditions. (2) CLUSTER: "Computational/Parallel Processing Studies": Flows in Local Chemical Equilibrium; A Computational Method for Solving Very Large Problems; Modeling of Cavitating Flows.
The main factor affecting the competitiveness of Contractor Company
NASA Astrophysics Data System (ADS)
Nurisra; Malahayati, Nurul; Mahmuddin
2018-05-01
Contractor companies must have the competitive advantage to compete in maintaining the survival of the company. Problems arise because quite a lot of advantages can be used and these advantages must be used appropriately to produce competitiveness for the company to continue to compete and to win the competition. This study aims to determine the main factors affecting the competitiveness of medium-class contractors in Banda Aceh. Data collection was obtained through questionnaires distributed to 31 middle-class contractors in Banda Aceh. Data processing and analysis is done by using descriptive analysis. Based on the result of descriptive analysis, it can be concluded that the most important competitiveness factor with a mean score value 4.52 is the relationship, and the factor that has the highest mean score value is the relationship with the government of 4.97, while the result of the ranking analysis is obtained 25 factor that is critical to the competitiveness of medium-class contractors in Banda Aceh.
Long-range interactions and parallel scalability in molecular simulations
NASA Astrophysics Data System (ADS)
Patra, Michael; Hyvönen, Marja T.; Falck, Emma; Sabouri-Ghomi, Mohsen; Vattulainen, Ilpo; Karttunen, Mikko
2007-01-01
Typical biomolecular systems such as cellular membranes, DNA, and protein complexes are highly charged. Thus, efficient and accurate treatment of electrostatic interactions is of great importance in computational modeling of such systems. We have employed the GROMACS simulation package to perform extensive benchmarking of different commonly used electrostatic schemes on a range of computer architectures (Pentium-4, IBM Power 4, and Apple/IBM G5) for single processor and parallel performance up to 8 nodes—we have also tested the scalability on four different networks, namely Infiniband, GigaBit Ethernet, Fast Ethernet, and nearly uniform memory architecture, i.e. communication between CPUs is possible by directly reading from or writing to other CPUs' local memory. It turns out that the particle-mesh Ewald method (PME) performs surprisingly well and offers competitive performance unless parallel runs on PC hardware with older network infrastructure are needed. Lipid bilayers of sizes 128, 512 and 2048 lipid molecules were used as the test systems representing typical cases encountered in biomolecular simulations. Our results enable an accurate prediction of computational speed on most current computing systems, both for serial and parallel runs. These results should be helpful in, for example, choosing the most suitable configuration for a small departmental computer cluster.
Miyazaki, Taisuke; Yamasaki, Miwako; Takeuchi, Tomonori; Sakimura, Kenji; Mishina, Masayoshi; Watanabe, Masahiko
2010-11-10
Glutamate receptor GluRδ2 is exclusively expressed in Purkinje cells (PCs) from early development and plays key roles in parallel fiber (PF) synapse formation, elimination of surplus climbing fibers (CFs), long-term depression, motor coordination, and motor learning. To address its role in adulthood, we previously developed a mouse model of drug-induced GluRδ2 ablation in adult PCs (Takeuchi et al., 2005). In that study, we demonstrated an essential role to maintain the connectivity of PF-PC synapses, based on the observation that both mismatching of presynaptic and postsynaptic specializations and disconnection of PF-PC synapses are progressively increased after GluRδ2 ablation. Here, we pursued its role for CF wiring in adult cerebellum. In parallel with the disconnection of PF-PC synapses, ascending CF branches exhibited distal extension to innervate distal dendrites of the target and neighboring PCs. Furthermore, transverse CF branches, a short motile collateral rarely forming synapses in wild-type animals, displayed aberrant mediolateral extension to innervate distal dendrites of neighboring and remote PCs. Consequently, many PCs were wired by single main CF and other surplus CFs innervating a small part of distal dendrites. Electrophysiological recording further revealed that surplus CF-EPSCs characterized with slow rise time and small amplitude emerged after GluRδ2 ablation, and increased progressively both in number and amplitude. Therefore, GluRδ2 is essential for maintaining CF monoinnervation in adult cerebellum by suppressing aberrant invasion of CF branches to the territory of PF innervation. Thus, GluRδ2 fuels heterosynaptic competition and gives PFs the competitive advantages over CFs throughout the animal's life.
ERIC Educational Resources Information Center
Green, Samuel B.; Levy, Roy; Thompson, Marilyn S.; Lu, Min; Lo, Wen-Juo
2012-01-01
A number of psychometricians have argued for the use of parallel analysis to determine the number of factors. However, parallel analysis must be viewed at best as a heuristic approach rather than a mathematically rigorous one. The authors suggest a revision to parallel analysis that could improve its accuracy. A Monte Carlo study is conducted to…
Public and private sector interactions: an economic perspective.
Maynard, A
1986-01-01
The debate about the public-private mix for health care has been dominated by rhetoric and the failure to evaluate the characteristics of the outcomes of public and private health care systems and to relate these to policy targets. After a brief analysis of the competing, liberal (conservative) and collectivist (socialist), objectives, the nature of the private health care sector in Britain is described and it is shown that growth has faltered due to cost containment problems. This outcome is the product of characteristics of the private health care system, paralleled precisely in the NHS: asymmetry information, monopoly power, moral hazard and third party pays. The final section discusses briefly some remedies for the inefficient and inequitable outcomes which are seen in all health care markets and it is argued that competition within public and private health care systems may enable each system type to achieve its own particular objectives more efficiently.
Structural Analysis of Competitive Forces in Higher Education Industry: A Conceptual Framework.
ERIC Educational Resources Information Center
Sisaye, Seleshi
This report describes how colleges and universities in the Not-for-Profit sector can bridge the strategic management research gap by applying competitive analysis in the strategic planning process. This business analysis tool can be used to assist colleges and universities, just as it assists businesses, in understanding the competitive forces…
Measuring the Indonesian provinces competitiveness by using PCA technique
NASA Astrophysics Data System (ADS)
Runita, Ditha; Fajriyah, Rohmatul
2017-12-01
Indonesia is a country which has vast teritoty. It has 34 provinces. Building local competitiveness is critical to enhance the long-term national competitiveness especially for a country as diverse as Indonesia. A competitive local government can attract and maintain successful firms and increase living standards for its inhabitants, because investment and skilled workers gravitate from uncompetitive regions to more competitive ones. Altough there are other methods to measuring competitiveness, but here we have demonstrated a simple method using principal component analysis (PCA). It can directly be applied to correlated, multivariate data. The analysis on Indonesian provinces provides 3 clusters based on the competitiveness measurement and the clusters are Bad, Good and Best perform provinces.
Comparing multi-module connections in membrane chromatography scale-up.
Yu, Zhou; Karkaria, Tishtar; Espina, Marianela; Hunjun, Manjeet; Surendran, Abera; Luu, Tina; Telychko, Julia; Yang, Yan-Ping
2015-07-20
Membrane chromatography is increasingly used for protein purification in the biopharmaceutical industry. Membrane adsorbers are often pre-assembled by manufacturers as ready-to-use modules. In large-scale protein manufacturing settings, the use of multiple membrane modules for a single batch is often required due to the large quantity of feed material. The question as to how multiple modules can be connected to achieve optimum separation and productivity has been previously approached using model proteins and mass transport theories. In this study, we compare the performance of multiple membrane modules in series and in parallel in the production of a protein antigen. Series connection was shown to provide superior separation compared to parallel connection in the context of competitive adsorption. Copyright © 2015 Elsevier B.V. All rights reserved.
CFD Research, Parallel Computation and Aerodynamic Optimization
NASA Technical Reports Server (NTRS)
Ryan, James S.
1995-01-01
During the last five years, CFD has matured substantially. Pure CFD research remains to be done, but much of the focus has shifted to integration of CFD into the design process. The work under these cooperative agreements reflects this trend. The recent work, and work which is planned, is designed to enhance the competitiveness of the US aerospace industry. CFD and optimization approaches are being developed and tested, so that the industry can better choose which methods to adopt in their design processes. The range of computer architectures has been dramatically broadened, as the assumption that only huge vector supercomputers could be useful has faded. Today, researchers and industry can trade off time, cost, and availability, choosing vector supercomputers, scalable parallel architectures, networked workstations, or heterogenous combinations of these to complete required computations efficiently.
NASA Technical Reports Server (NTRS)
Nguyen, D. T.; Al-Nasra, M.; Zhang, Y.; Baddourah, M. A.; Agarwal, T. K.; Storaasli, O. O.; Carmona, E. A.
1991-01-01
Several parallel-vector computational improvements to the unconstrained optimization procedure are described which speed up the structural analysis-synthesis process. A fast parallel-vector Choleski-based equation solver, pvsolve, is incorporated into the well-known SAP-4 general-purpose finite-element code. The new code, denoted PV-SAP, is tested for static structural analysis. Initial results on a four processor CRAY 2 show that using pvsolve reduces the equation solution time by a factor of 14-16 over the original SAP-4 code. In addition, parallel-vector procedures for the Golden Block Search technique and the BFGS method are developed and tested for nonlinear unconstrained optimization. A parallel version of an iterative solver and the pvsolve direct solver are incorporated into the BFGS method. Preliminary results on nonlinear unconstrained optimization test problems, using pvsolve in the analysis, show excellent parallel-vector performance indicating that these parallel-vector algorithms can be used in a new generation of finite-element based structural design/analysis-synthesis codes.
Parallel computing for probabilistic fatigue analysis
NASA Technical Reports Server (NTRS)
Sues, Robert H.; Lua, Yuan J.; Smith, Mark D.
1993-01-01
This paper presents the results of Phase I research to investigate the most effective parallel processing software strategies and hardware configurations for probabilistic structural analysis. We investigate the efficiency of both shared and distributed-memory architectures via a probabilistic fatigue life analysis problem. We also present a parallel programming approach, the virtual shared-memory paradigm, that is applicable across both types of hardware. Using this approach, problems can be solved on a variety of parallel configurations, including networks of single or multiprocessor workstations. We conclude that it is possible to effectively parallelize probabilistic fatigue analysis codes; however, special strategies will be needed to achieve large-scale parallelism to keep large number of processors busy and to treat problems with the large memory requirements encountered in practice. We also conclude that distributed-memory architecture is preferable to shared-memory for achieving large scale parallelism; however, in the future, the currently emerging hybrid-memory architectures will likely be optimal.
Murphy, Brian M; Dandy, David S; Henry, Charles S
2009-04-27
Immunoassays represent a core workhorse methodology for many applications ranging from clinical diagnostics to environmental monitoring. In traditional formats such as the enzyme linked immunosorbent assay (ELISA), analytes are measured singly or in small sets. As more biomarkers are identified for disease states, there is a need to develop methods that can measure multiple markers simultaneously. Immunoaffinity arrays are one such chemistry that can achieve multi-marker screening. Most arrays are performed in either competitive or non-competitive formats, where the former are used predominantly for small molecules and the later for macromolecules. To date, ELISA and immunoaffinity array methods have relied exclusively on one of these formats and not the other. Here an immunoaffinity array method capable of performing simultaneous competitive and non-competitive analysis generated using micromosaic immunoassay techniques is introduced for the analysis of metabolites and proteins. In this report, three markers of oxidative stress were used as a model system. The method described here demonstrates the simultaneous analysis of 3-nitrotyrosine, by indirect competitive immunoassay while the enzymes catalase and superoxide dismutase are analyzed by non-competitive sandwich immunoassay. The method requires less than 1 microL sample and 45 min for completion. Logistic curve fits and LOD (limits of detection) statistical analysis of the binding results are presented and show good agreement with published data for these antibody-antigen systems.
NASA Technical Reports Server (NTRS)
Farhat, Charbel
1998-01-01
In this grant, we have proposed a three-year research effort focused on developing High Performance Computation and Communication (HPCC) methodologies for structural analysis on parallel processors and clusters of workstations, with emphasis on reducing the structural design cycle time. Besides consolidating and further improving the FETI solver technology to address plate and shell structures, we have proposed to tackle the following design related issues: (a) parallel coupling and assembly of independently designed and analyzed three-dimensional substructures with non-matching interfaces, (b) fast and smart parallel re-analysis of a given structure after it has undergone design modifications, (c) parallel evaluation of sensitivity operators (derivatives) for design optimization, and (d) fast parallel analysis of mildly nonlinear structures. While our proposal was accepted, support was provided only for one year.
A new parallel-vector finite element analysis software on distributed-memory computers
NASA Technical Reports Server (NTRS)
Qin, Jiangning; Nguyen, Duc T.
1993-01-01
A new parallel-vector finite element analysis software package MPFEA (Massively Parallel-vector Finite Element Analysis) is developed for large-scale structural analysis on massively parallel computers with distributed-memory. MPFEA is designed for parallel generation and assembly of the global finite element stiffness matrices as well as parallel solution of the simultaneous linear equations, since these are often the major time-consuming parts of a finite element analysis. Block-skyline storage scheme along with vector-unrolling techniques are used to enhance the vector performance. Communications among processors are carried out concurrently with arithmetic operations to reduce the total execution time. Numerical results on the Intel iPSC/860 computers (such as the Intel Gamma with 128 processors and the Intel Touchstone Delta with 512 processors) are presented, including an aircraft structure and some very large truss structures, to demonstrate the efficiency and accuracy of MPFEA.
NASA Astrophysics Data System (ADS)
Shimizu, Yasunobu; Matsumoto, Yuji; Aoki, Kosuke; Kimura, Noriaki; Aoki, Haruyoshi
2012-04-01
We have performed an extensive study on the electronic transport properties of CexLa1-xRu2Si2. At zero field or under the fields parallel to the hard axis of magnetization, the residual resistivity, magnetoresistivity and Hall resistivity are found to be most enhanced around x = 0.85 in the antiferromagnetic state. On the other hand, the high magnetic field along the easy axis is effective to suppress the enhancement. The coherence temperature derived from the temperature variation of Hall coefficient becomes equal to the antiferromagnetic transition temperature at x = 0.85, indicating that the competition between the coherence of the Kondo singlet and the long range magnetic order is responsible for the enhancement. The competition is likely to affect also the magnetic properties in the antiferromagnetic state. The comparison with the de Haas--van Alphen effect measurements suggests that the enhancement is likely to be due to the increase in scattering. The present results are compared with the theory by Hattori and Miyake.
Evaluation of Parallel Analysis Methods for Determining the Number of Factors
ERIC Educational Resources Information Center
Crawford, Aaron V.; Green, Samuel B.; Levy, Roy; Lo, Wen-Juo; Scott, Lietta; Svetina, Dubravka; Thompson, Marilyn S.
2010-01-01
Population and sample simulation approaches were used to compare the performance of parallel analysis using principal component analysis (PA-PCA) and parallel analysis using principal axis factoring (PA-PAF) to identify the number of underlying factors. Additionally, the accuracies of the mean eigenvalue and the 95th percentile eigenvalue criteria…
Feature Augmentation via Nonparametrics and Selection (FANS) in High-Dimensional Classification.
Fan, Jianqing; Feng, Yang; Jiang, Jiancheng; Tong, Xin
We propose a high dimensional classification method that involves nonparametric feature augmentation. Knowing that marginal density ratios are the most powerful univariate classifiers, we use the ratio estimates to transform the original feature measurements. Subsequently, penalized logistic regression is invoked, taking as input the newly transformed or augmented features. This procedure trains models equipped with local complexity and global simplicity, thereby avoiding the curse of dimensionality while creating a flexible nonlinear decision boundary. The resulting method is called Feature Augmentation via Nonparametrics and Selection (FANS). We motivate FANS by generalizing the Naive Bayes model, writing the log ratio of joint densities as a linear combination of those of marginal densities. It is related to generalized additive models, but has better interpretability and computability. Risk bounds are developed for FANS. In numerical analysis, FANS is compared with competing methods, so as to provide a guideline on its best application domain. Real data analysis demonstrates that FANS performs very competitively on benchmark email spam and gene expression data sets. Moreover, FANS is implemented by an extremely fast algorithm through parallel computing.
Feature Augmentation via Nonparametrics and Selection (FANS) in High-Dimensional Classification
Feng, Yang; Jiang, Jiancheng; Tong, Xin
2015-01-01
We propose a high dimensional classification method that involves nonparametric feature augmentation. Knowing that marginal density ratios are the most powerful univariate classifiers, we use the ratio estimates to transform the original feature measurements. Subsequently, penalized logistic regression is invoked, taking as input the newly transformed or augmented features. This procedure trains models equipped with local complexity and global simplicity, thereby avoiding the curse of dimensionality while creating a flexible nonlinear decision boundary. The resulting method is called Feature Augmentation via Nonparametrics and Selection (FANS). We motivate FANS by generalizing the Naive Bayes model, writing the log ratio of joint densities as a linear combination of those of marginal densities. It is related to generalized additive models, but has better interpretability and computability. Risk bounds are developed for FANS. In numerical analysis, FANS is compared with competing methods, so as to provide a guideline on its best application domain. Real data analysis demonstrates that FANS performs very competitively on benchmark email spam and gene expression data sets. Moreover, FANS is implemented by an extremely fast algorithm through parallel computing. PMID:27185970
Scaling Deep Learning Workloads: NVIDIA DGX-1/Pascal and Intel Knights Landing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gawande, Nitin A.; Landwehr, Joshua B.; Daily, Jeffrey A.
Deep Learning (DL) algorithms have become ubiquitous in data analytics. As a result, major computing vendors --- including NVIDIA, Intel, AMD and IBM --- have architectural road-maps influenced by DL workloads. Furthermore, several vendors have recently advertised new computing products as accelerating DL workloads. Unfortunately, it is difficult for data scientists to quantify the potential of these different products. This paper provides a performance and power analysis of important DL workloads on two major parallel architectures: NVIDIA DGX-1 (eight Pascal P100 GPUs interconnected with NVLink) and Intel Knights Landing (KNL) CPUs interconnected with Intel Omni-Path. Our evaluation consists of amore » cross section of convolutional neural net workloads: CifarNet, CaffeNet, AlexNet and GoogleNet topologies using the Cifar10 and ImageNet datasets. The workloads are vendor optimized for each architecture. GPUs provide the highest overall raw performance. Our analysis indicates that although GPUs provide the highest overall performance, the gap can close for some convolutional networks; and KNL can be competitive when considering performance/watt. Furthermore, NVLink is critical to GPU scaling.« less
Possibilities of fractal analysis of the competitive dynamics: Approaches and procedures
NASA Astrophysics Data System (ADS)
Zagornaya, T. O.; Medvedeva, M. A.; Panova, V. L.; Isaichik, K. F.; Medvedev, A. N.
2017-11-01
The possibilities of the fractal approach are used for the study of non-linear nature of the competitive dynamics of the market of trading intermediaries. Based on a statistical study of the functioning of retail indicators in the region, the approach to the analysis of the characteristics of the competitive behavior of market participants is developed. The authors postulate the principles of studying the dynamics of competition as a result of changes in the characteristics of the vector and the competitive behavior of market agents.
ERIC Educational Resources Information Center
Çokluk, Ömay; Koçak, Duygu
2016-01-01
In this study, the number of factors obtained from parallel analysis, a method used for determining the number of factors in exploratory factor analysis, was compared to that of the factors obtained from eigenvalue and scree plot--two traditional methods for determining the number of factors--in terms of consistency. Parallel analysis is based on…
Thread concept for automatic task parallelization in image analysis
NASA Astrophysics Data System (ADS)
Lueckenhaus, Maximilian; Eckstein, Wolfgang
1998-09-01
Parallel processing of image analysis tasks is an essential method to speed up image processing and helps to exploit the full capacity of distributed systems. However, writing parallel code is a difficult and time-consuming process and often leads to an architecture-dependent program that has to be re-implemented when changing the hardware. Therefore it is highly desirable to do the parallelization automatically. For this we have developed a special kind of thread concept for image analysis tasks. Threads derivated from one subtask may share objects and run in the same context but may process different threads of execution and work on different data in parallel. In this paper we describe the basics of our thread concept and show how it can be used as basis of an automatic task parallelization to speed up image processing. We further illustrate the design and implementation of an agent-based system that uses image analysis threads for generating and processing parallel programs by taking into account the available hardware. The tests made with our system prototype show that the thread concept combined with the agent paradigm is suitable to speed up image processing by an automatic parallelization of image analysis tasks.
Bois, Julien E; Lalanne, Julien; Delforge, Catherine
2009-08-01
We examined parental influence on athletes' pre-competitive anxiety. The effect of parental presence during competition was studied as was the role of parenting practices. Data were collected from a sample of 341 athletes (201 basketball players and 140 tennis players) before an official competition. Analysis of variance indicated that the presence of both parents was associated with higher pre-competitive anxiety for all participants, except male tennis players. The absence of both parents did not result in less anxiety. A second analysis of variance revealed that females tennis players at provincial and national level perceived greater parental pressure than most other participants. Canonical correlation analysis showed a positive relationship between pre-competitive anxiety and parenting practices for tennis players, but not for basketball players. Directive behaviours and pressure were positively associated with pre-competitive anxiety for all tennis players, whereas praise and understanding was negatively related to anxiety for female tennis players only.
Carlson, Ross P; Beck, Ashley E; Phalak, Poonam; Fields, Matthew W; Gedeon, Tomas; Hanley, Luke; Harcombe, William R; Henson, Michael A; Heys, Jeffrey J
2018-04-17
Resource scarcity is a common stress in nature and has a major impact on microbial physiology. This review highlights microbial acclimations to resource scarcity, focusing on resource investment strategies for chemoheterotrophs from the molecular level to the pathway level. Competitive resource allocation strategies often lead to a phenotype known as overflow metabolism; the resulting overflow byproducts can stabilize cooperative interactions in microbial communities and can lead to cross-feeding consortia. These consortia can exhibit emergent properties such as enhanced resource usage and biomass productivity. The literature distilled here draws parallels between in silico and laboratory studies and ties them together with ecological theories to better understand microbial stress responses and mutualistic consortia functioning. © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.
A connectionist model for diagnostic problem solving
NASA Technical Reports Server (NTRS)
Peng, Yun; Reggia, James A.
1989-01-01
A competition-based connectionist model for solving diagnostic problems is described. The problems considered are computationally difficult in that (1) multiple disorders may occur simultaneously and (2) a global optimum in the space exponential to the total number of possible disorders is sought as a solution. The diagnostic problem is treated as a nonlinear optimization problem, and global optimization criteria are decomposed into local criteria governing node activation updating in the connectionist model. Nodes representing disorders compete with each other to account for each individual manifestation, yet complement each other to account for all manifestations through parallel node interactions. When equilibrium is reached, the network settles into a locally optimal state. Three randomly generated examples of diagnostic problems, each of which has 1024 cases, were tested, and the decomposition plus competition plus resettling approach yielded very high accuracy.
About Edible Restaurants: Conflicts between Syntax and Semantics as Revealed by ERPs
Kos, Miriam; Vosse, Theo; van den Brink, Daniëlle; Hagoort, Peter
2010-01-01
In order to investigate conflicts between semantics and syntax, we recorded ERPs, while participants read Dutch sentences. Sentences containing conflicts between syntax and semantics (Fred eats in a sandwich…/Fred eats a restaurant…) elicited an N400. These results show that conflicts between syntax and semantics not necessarily lead to P600 effects and are in line with the processing competition account. According to this parallel account the syntactic and semantic processing streams are fully interactive and information from one level can influence the processing at another level. The relative strength of the cues of the processing streams determines which level is affected most strongly by the conflict. The processing competition account maintains the distinction between the N400 as index for semantic processing and the P600 as index for structural processing. PMID:21833277
Lattice Boltzmann model for simulation of magnetohydrodynamics
NASA Technical Reports Server (NTRS)
Chen, Shiyi; Chen, Hudong; Martinez, Daniel; Matthaeus, William
1991-01-01
A numerical method, based on a discrete Boltzmann equation, is presented for solving the equations of magnetohydrodynamics (MHD). The algorithm provides advantages similar to the cellular automaton method in that it is local and easily adapted to parallel computing environments. Because of much lower noise levels and less stringent requirements on lattice size, the method appears to be more competitive with traditional solution methods. Examples show that the model accurately reproduces both linear and nonlinear MHD phenomena.
Techno-economic comparison of series hybrid, plug-in hybrid, fuel cell and regular cars
NASA Astrophysics Data System (ADS)
van Vliet, Oscar P. R.; Kruithof, Thomas; Turkenburg, Wim C.; Faaij, André P. C.
We examine the competitiveness of series hybrid compared to fuel cell, parallel hybrid, and regular cars. We use public domain data to determine efficiency, fuel consumption, total costs of ownership and greenhouse gas emissions resulting from drivetrain choices. The series hybrid drivetrain can be seen both as an alternative to petrol, diesel and parallel hybrid cars, as well as an intermediate stage towards fully electric or fuel cell cars. We calculate the fuel consumption and costs of four diesel-fuelled series hybrid, four plug-in hybrid and four fuel cell car configurations, and compared these to three reference cars. We find that series hybrid cars may reduce fuel consumption by 34-47%, but cost €5000-12,000 more. Well-to-wheel greenhouse gas emissions may be reduced to 89-103 g CO 2 km -1 compared to reference petrol (163 g km -1) and diesel cars (156 g km -1). Series hybrid cars with wheel motors have lower weight and 7-21% lower fuel consumption than those with central electric motors. The fuel cell car remains uncompetitive even if production costs of fuel cells come down by 90%. Plug-in hybrid cars are competitive when driving large distances on electricity, and/or if cost of batteries come down substantially. Well-to-wheel greenhouse gas emissions may be reduced to 60-69 g CO 2 km -1.
Application of parallelized software architecture to an autonomous ground vehicle
NASA Astrophysics Data System (ADS)
Shakya, Rahul; Wright, Adam; Shin, Young Ho; Momin, Orko; Petkovsek, Steven; Wortman, Paul; Gautam, Prasanna; Norton, Adam
2011-01-01
This paper presents improvements made to Q, an autonomous ground vehicle designed to participate in the Intelligent Ground Vehicle Competition (IGVC). For the 2010 IGVC, Q was upgraded with a new parallelized software architecture and a new vision processor. Improvements were made to the power system reducing the number of batteries required for operation from six to one. In previous years, a single state machine was used to execute the bulk of processing activities including sensor interfacing, data processing, path planning, navigation algorithms and motor control. This inefficient approach led to poor software performance and made it difficult to maintain or modify. For IGVC 2010, the team implemented a modular parallel architecture using the National Instruments (NI) LabVIEW programming language. The new architecture divides all the necessary tasks - motor control, navigation, sensor data collection, etc. into well-organized components that execute in parallel, providing considerable flexibility and facilitating efficient use of processing power. Computer vision is used to detect white lines on the ground and determine their location relative to the robot. With the new vision processor and some optimization of the image processing algorithm used last year, two frames can be acquired and processed in 70ms. With all these improvements, Q placed 2nd in the autonomous challenge.
Cache-Oblivious parallel SIMD Viterbi decoding for sequence search in HMMER.
Ferreira, Miguel; Roma, Nuno; Russo, Luis M S
2014-05-30
HMMER is a commonly used bioinformatics tool based on Hidden Markov Models (HMMs) to analyze and process biological sequences. One of its main homology engines is based on the Viterbi decoding algorithm, which was already highly parallelized and optimized using Farrar's striped processing pattern with Intel SSE2 instruction set extension. A new SIMD vectorization of the Viterbi decoding algorithm is proposed, based on an SSE2 inter-task parallelization approach similar to the DNA alignment algorithm proposed by Rognes. Besides this alternative vectorization scheme, the proposed implementation also introduces a new partitioning of the Markov model that allows a significantly more efficient exploitation of the cache locality. Such optimization, together with an improved loading of the emission scores, allows the achievement of a constant processing throughput, regardless of the innermost-cache size and of the dimension of the considered model. The proposed optimized vectorization of the Viterbi decoding algorithm was extensively evaluated and compared with the HMMER3 decoder to process DNA and protein datasets, proving to be a rather competitive alternative implementation. Being always faster than the already highly optimized ViterbiFilter implementation of HMMER3, the proposed Cache-Oblivious Parallel SIMD Viterbi (COPS) implementation provides a constant throughput and offers a processing speedup as high as two times faster, depending on the model's size.
Lu, Xiaofeng; Song, Li; Shen, Sumin; He, Kang; Yu, Songyu; Ling, Nam
2013-01-01
Hough Transform has been widely used for straight line detection in low-definition and still images, but it suffers from execution time and resource requirements. Field Programmable Gate Arrays (FPGA) provide a competitive alternative for hardware acceleration to reap tremendous computing performance. In this paper, we propose a novel parallel Hough Transform (PHT) and FPGA architecture-associated framework for real-time straight line detection in high-definition videos. A resource-optimized Canny edge detection method with enhanced non-maximum suppression conditions is presented to suppress most possible false edges and obtain more accurate candidate edge pixels for subsequent accelerated computation. Then, a novel PHT algorithm exploiting spatial angle-level parallelism is proposed to upgrade computational accuracy by improving the minimum computational step. Moreover, the FPGA based multi-level pipelined PHT architecture optimized by spatial parallelism ensures real-time computation for 1,024 × 768 resolution videos without any off-chip memory consumption. This framework is evaluated on ALTERA DE2-115 FPGA evaluation platform at a maximum frequency of 200 MHz, and it can calculate straight line parameters in 15.59 ms on the average for one frame. Qualitative and quantitative evaluation results have validated the system performance regarding data throughput, memory bandwidth, resource, speed and robustness. PMID:23867746
Lu, Xiaofeng; Song, Li; Shen, Sumin; He, Kang; Yu, Songyu; Ling, Nam
2013-07-17
Hough Transform has been widely used for straight line detection in low-definition and still images, but it suffers from execution time and resource requirements. Field Programmable Gate Arrays (FPGA) provide a competitive alternative for hardware acceleration to reap tremendous computing performance. In this paper, we propose a novel parallel Hough Transform (PHT) and FPGA architecture-associated framework for real-time straight line detection in high-definition videos. A resource-optimized Canny edge detection method with enhanced non-maximum suppression conditions is presented to suppress most possible false edges and obtain more accurate candidate edge pixels for subsequent accelerated computation. Then, a novel PHT algorithm exploiting spatial angle-level parallelism is proposed to upgrade computational accuracy by improving the minimum computational step. Moreover, the FPGA based multi-level pipelined PHT architecture optimized by spatial parallelism ensures real-time computation for 1,024 × 768 resolution videos without any off-chip memory consumption. This framework is evaluated on ALTERA DE2-115 FPGA evaluation platform at a maximum frequency of 200 MHz, and it can calculate straight line parameters in 15.59 ms on the average for one frame. Qualitative and quantitative evaluation results have validated the system performance regarding data throughput, memory bandwidth, resource, speed and robustness.
NASA Astrophysics Data System (ADS)
Sunderland, Zofia; Patorski, Krzysztof
2016-12-01
A big challenge for standard interferogram analysis methods such as Temporal Phase Shifting or Fourier Transform is a parasitic set of fringes which might occur in the analyzed fringe pattern intensity distribution. It is encountered, for example, when transparent glass plates with quasi-parallel surfaces are tested in Fizeau or Twyman-Green interferometers. Besides the beams reflected from the plate front surface and the interferometer reference the beam reflected from the plate rear surface also plays important role; its amplitude is comparable with the amplitude of other beams. In result we face three families of fringes of high contrast which cannot be easily separated. Earlier we proposed a competitive solution for flatness measurements which relies on eliminating one of those fringe sets from the three-beam interferogram and separating two remaining ones with the use of 2D Continuous Wavelet Transform. In this work we cover the case when the intensity of the reference beam is significantly higher than the intensities of two object beams. The main advantage of differentiating beam intensities is the change in contrast of individual fringe families. Processing of such three-beam interferograms is modified but also takes advantage of 2D CWT. We show how to implement this method in Twyman-Green and Fizeau setups and compare this processing path and measurement procedures with previously proposed solutions.
2011-01-01
Background Natural communities are structured by intra-guild competition, predation or parasitism and the abiotic environment. We studied the relative importance of these factors in two host-social parasite ecosystems in three ant communities in Europe (Bavaria) and North America (New York, West Virginia). We tested how these factors affect colony demography, life-history and the spatial pattern of colonies, using a large sample size of more than 1000 colonies. The strength of competition was measured by the distance to the nearest competitor. Distance to the closest social parasite colony was used as a measure of parasitism risk. Nest sites (i.e., sticks or acorns) are limited in these forest ecosystems and we therefore included nest site quality as an abiotic factor in the analysis. In contrast to previous studies based on local densities, we focus here on the positioning and spatial patterns and we use models to compare our predictions to random expectations. Results Colony demography was universally affected by the size of the nest site with larger and more productive colonies residing in larger nest sites of higher quality. Distance to the nearest competitor negatively influenced host demography and brood production in the Bavarian community, pointing to an important role of competition, while social parasitism was less influential in this community. The New York community was characterized by the highest habitat variability, and productive colonies were clustered in sites of higher quality. Colonies were clumped on finer spatial scales, when we considered only the nearest neighbors, but more regularly distributed on coarser scales. The analysis of spatial positioning within plots often produced different results compared to those based on colony densities. For example, while host and slavemaker densities are often positively correlated, slavemakers do not nest closer to potential host colonies than expected by random. Conclusions The three communities are differently affected by biotic and abiotic factors. Some of the differences can be attributed to habitat differences and some to differences between the two slavemaking-host ecosystems. The strong effect of competition in the Bavarian community points to the scarcity of resources in this uniform habitat compared to the other more diverse sites. The decrease in colony aggregation with scale indicates fine-scale resource hotspots: colonies are locally aggregated in small groups. Our study demonstrates that species relationships vary across scales and spatial patterns can provide important insights into species interactions. These results could not have been obtained with analyses based on local densities alone. Previous studies focused on social parasitism and its effect on host colonies. The broader approach taken here, considering several possible factors affecting colony demography and not testing each one in isolation, shows that competition and environmental variability can have a similar strong impact on demography and life-history of hosts. We conclude that the effects of parasites or predators should be studied in parallel to other ecological influences. PMID:21443778
Scharf, Inon; Fischer-Blass, Birgit; Foitzik, Susanne
2011-03-28
Natural communities are structured by intra-guild competition, predation or parasitism and the abiotic environment. We studied the relative importance of these factors in two host-social parasite ecosystems in three ant communities in Europe (Bavaria) and North America (New York, West Virginia). We tested how these factors affect colony demography, life-history and the spatial pattern of colonies, using a large sample size of more than 1000 colonies. The strength of competition was measured by the distance to the nearest competitor. Distance to the closest social parasite colony was used as a measure of parasitism risk. Nest sites (i.e., sticks or acorns) are limited in these forest ecosystems and we therefore included nest site quality as an abiotic factor in the analysis. In contrast to previous studies based on local densities, we focus here on the positioning and spatial patterns and we use models to compare our predictions to random expectations. Colony demography was universally affected by the size of the nest site with larger and more productive colonies residing in larger nest sites of higher quality. Distance to the nearest competitor negatively influenced host demography and brood production in the Bavarian community, pointing to an important role of competition, while social parasitism was less influential in this community. The New York community was characterized by the highest habitat variability, and productive colonies were clustered in sites of higher quality. Colonies were clumped on finer spatial scales, when we considered only the nearest neighbors, but more regularly distributed on coarser scales. The analysis of spatial positioning within plots often produced different results compared to those based on colony densities. For example, while host and slavemaker densities are often positively correlated, slavemakers do not nest closer to potential host colonies than expected by random. The three communities are differently affected by biotic and abiotic factors. Some of the differences can be attributed to habitat differences and some to differences between the two slavemaking-host ecosystems. The strong effect of competition in the Bavarian community points to the scarcity of resources in this uniform habitat compared to the other more diverse sites. The decrease in colony aggregation with scale indicates fine-scale resource hotspots: colonies are locally aggregated in small groups. Our study demonstrates that species relationships vary across scales and spatial patterns can provide important insights into species interactions. These results could not have been obtained with analyses based on local densities alone. Previous studies focused on social parasitism and its effect on host colonies. The broader approach taken here, considering several possible factors affecting colony demography and not testing each one in isolation, shows that competition and environmental variability can have a similar strong impact on demography and life-history of hosts. We conclude that the effects of parasites or predators should be studied in parallel to other ecological influences.
Why not private health insurance? 2. Actuarial principles meet provider dreams
Deber, R; Gildiner, A; Baranek, P
1999-01-01
What do insurers and employers feel about proposals to expand Canadian health care financing through private insurance, in either a parallel stream or a supplementary tier? The authors conducted 10 semistructured, open-ended interviews in the autumn and early winter of 1996 with representatives of the insurance industry and benefits managers working with large employers; respondents were identified using a snowball sampling technique. The respondents felt that proposals for parallel private plans within a competitive market are incompatible with insurance principles, as long as a well-functioning and relatively comprehensive public system continues to exist; the maintenance of a strong public system was both socially and economically desirable. With the exception of serving the niche market for the private management of return-to-work strategies, respondents showed little interest in providing parallel coverage. They were receptive to a larger role for supplementary insurance but cautioned that they are not willing to cover all delisted services. As business executives they stated that they are willing to insure only services and clients that will be profitable. PMID:10497614
Super-resolved Parallel MRI by Spatiotemporal Encoding
Schmidt, Rita; Baishya, Bikash; Ben-Eliezer, Noam; Seginer, Amir; Frydman, Lucio
2016-01-01
Recent studies described an alternative “ultrafast” scanning method based on spatiotemporal (SPEN) principles. SPEN demonstrates numerous potential advantages over EPI-based alternatives, at no additional expense in experimental complexity. An important aspect that SPEN still needs to achieve for providing a competitive acquisition alternative entails exploiting parallel imaging algorithms, without compromising its proven capabilities. The present work introduces a combination of multi-band frequency-swept pulses simultaneously encoding multiple, partial fields-of-view; together with a new algorithm merging a Super-Resolved SPEN image reconstruction and SENSE multiple-receiving methods. The ensuing approach enables one to reduce both the excitation and acquisition times of ultrafast SPEN acquisitions by the customary acceleration factor R, without compromises in either the ensuing spatial resolution, SAR deposition, or the capability to operate in multi-slice mode. The performance of these new single-shot imaging sequences and their ancillary algorithms were explored on phantoms and human volunteers at 3T. The gains of the parallelized approach were particularly evident when dealing with heterogeneous systems subject to major T2/T2* effects, as is the case upon single-scan imaging near tissue/air interfaces. PMID:24120293
Message Passing and Shared Address Space Parallelism on an SMP Cluster
NASA Technical Reports Server (NTRS)
Shan, Hongzhang; Singh, Jaswinder P.; Oliker, Leonid; Biswas, Rupak; Biegel, Bryan (Technical Monitor)
2002-01-01
Currently, message passing (MP) and shared address space (SAS) are the two leading parallel programming paradigms. MP has been standardized with MPI, and is the more common and mature approach; however, code development can be extremely difficult, especially for irregularly structured computations. SAS offers substantial ease of programming, but may suffer from performance limitations due to poor spatial locality and high protocol overhead. In this paper, we compare the performance of and the programming effort required for six applications under both programming models on a 32-processor PC-SMP cluster, a platform that is becoming increasingly attractive for high-end scientific computing. Our application suite consists of codes that typically do not exhibit scalable performance under shared-memory programming due to their high communication-to-computation ratios and/or complex communication patterns. Results indicate that SAS can achieve about half the parallel efficiency of MPI for most of our applications, while being competitive for the others. A hybrid MPI+SAS strategy shows only a small performance advantage over pure MPI in some cases. Finally, improved implementations of two MPI collective operations on PC-SMP clusters are presented.
Why not private health insurance? 2. Actuarial principles meet provider dreams.
Deber, R; Gildiner, A; Baranek, P
1999-09-07
What do insurers and employers feel about proposals to expand Canadian health care financing through private insurance, in either a parallel stream or a supplementary tier? The authors conducted 10 semistructured, open-ended interviews in the autumn and early winter of 1996 with representatives of the insurance industry and benefits managers working with large employers; respondents were identified using a snowball sampling technique. The respondents felt that proposals for parallel private plans within a competitive market are incompatible with insurance principles, as long as a well-functioning and relatively comprehensive public system continues to exist; the maintenance of a strong public system was both socially and economically desirable. With the exception of serving the niche market for the private management of return-to-work strategies, respondents showed little interest in providing parallel coverage. They were receptive to a larger role for supplementary insurance but cautioned that they are not willing to cover all delisted services. As business executives they stated that they are willing to insure only services and clients that will be profitable.
Artioli, Guilherme G; Franchini, Emerson; Nicastro, Humberto; Sterkowicz, Stanislaw; Solis, Marina Y; Lancha, Antonio H
2010-05-04
Judo competitions are divided into weight classes. However, most athletes reduce their body weight in a few days before competition in order to obtain a competitive advantage over lighter opponents. To achieve fast weight reduction, athletes use a number of aggressive nutritional strategies so many of them place themselves at a high health-injury risk. In collegiate wrestling, a similar problem has been observed and three wrestlers died in 1997 due to rapid weight loss regimes. After these deaths, the National Collegiate Athletic Association had implemented a successful weight management program which was proven to improve weight management behavior. No similar program has ever been discussed by judo federations even though judo competitors present a comparable inappropriate pattern of weight control. In view of this, the basis for a weight control program is provided in this manuscript, as follows: competition should begin within 1 hour after weigh-in, at the latest; each athlete is allowed to be weighed-in only once; rapid weight loss as well as artificial rehydration (i.e., saline infusion) methods are prohibited during the entire competition day; athletes should pass the hydration test to get their weigh-in validated; an individual minimum competitive weight (male athletes competing at no less than 7% and females at no less than 12% of body fat) should be determined at the beginning of each season; athletes are not allowed to compete in any weight class that requires weight reductions greater than 1.5% of body weight per week. In parallel, educational programs should aim at increasing the athletes', coaches' and parents' awareness about the risks of aggressive nutritional strategies as well as healthier ways to properly manage body weight.
Rapid adaptation to mammalian sociality via sexually selected traits
2013-01-01
Background Laboratory studies show that the components of sexual selection (e.g., mate choice and intrasexual competition) can profoundly affect the development and fitness of offspring. Less is known, however, about the total effects of sexual selection on offspring in normal social conditions. Complex social networks, such as dominance hierarchies, regulate the opportunity for mating success, and are often missing from laboratory studies. Social selection is an extended view of sexual selection that incorporates competition during sexual and nonsexual interactions, and predicts complex evolutionary dynamics. Whether social selection improves or constrains offspring fitness is controversial. Results To identify fitness consequences of social selection, wild-derived mice that had bred under laboratory conditions for eight generations were re-introduced to naturalistic competition in enclosures for three consecutive generations (promiscuous line). In parallel, a control lineage bred in cages under random mate assignment (monogamous line). A direct competition experiment using second-generation animals revealed that promiscuous line males had greater reproductive success than monogamous line males (particularly during extra-territorial matings), in spite of higher mortality and equivalent success in social dominance and sperm competition. There were no major female fitness effects (though promiscuous line females had fewer litters than monogamous line females). This result suggested that selection primarily acted upon a sexually attractive male phenotype in the promiscuous line, a hypothesis we confirmed in female odor and mating preference trials. Conclusions We present novel evidence for the strength of sexual selection under normal social conditions, and show rapid male adaptation driven largely by sexual trait expression, with tradeoffs in survivorship and female fecundity. Re-introducing wild-derived mice to competition quickly uncovers sexually selected phenotypes otherwise lost in normal colony breeding. PMID:23577674
Influence of the extrinsic curvature on two-dimensional nematic films.
Napoli, Gaetano; Vergori, Luigi
2018-05-01
Nematic films are thin fluid structures, ideally two dimensional, endowed with an in-plane degenerate nematic order. In this paper we examine a generalization of the classical Plateau problem to an axisymmetric nematic film bounded by two coaxial parallel rings. At equilibrium, the shape of the nematic film results from the competition between surface tension, which favors the minimization of the area, and the nematic elasticity, which instead promotes the alignment of the molecules along a common direction. We find two classes of equilibrium solutions in which the molecules are uniformly aligned along the meridians or parallels. Depending on two dimensionless parameters, one related to the geometry of the film and the other to the constitutive moduli, the Gaussian curvature of the equilibrium shape may be everywhere negative, vanishing, or positive. The stability of these equilibrium configurations is investigated.
Influence of the extrinsic curvature on two-dimensional nematic films
NASA Astrophysics Data System (ADS)
Napoli, Gaetano; Vergori, Luigi
2018-05-01
Nematic films are thin fluid structures, ideally two dimensional, endowed with an in-plane degenerate nematic order. In this paper we examine a generalization of the classical Plateau problem to an axisymmetric nematic film bounded by two coaxial parallel rings. At equilibrium, the shape of the nematic film results from the competition between surface tension, which favors the minimization of the area, and the nematic elasticity, which instead promotes the alignment of the molecules along a common direction. We find two classes of equilibrium solutions in which the molecules are uniformly aligned along the meridians or parallels. Depending on two dimensionless parameters, one related to the geometry of the film and the other to the constitutive moduli, the Gaussian curvature of the equilibrium shape may be everywhere negative, vanishing, or positive. The stability of these equilibrium configurations is investigated.
Computational mechanics analysis tools for parallel-vector supercomputers
NASA Technical Reports Server (NTRS)
Storaasli, Olaf O.; Nguyen, Duc T.; Baddourah, Majdi; Qin, Jiangning
1993-01-01
Computational algorithms for structural analysis on parallel-vector supercomputers are reviewed. These parallel algorithms, developed by the authors, are for the assembly of structural equations, 'out-of-core' strategies for linear equation solution, massively distributed-memory equation solution, unsymmetric equation solution, general eigensolution, geometrically nonlinear finite element analysis, design sensitivity analysis for structural dynamics, optimization search analysis and domain decomposition. The source code for many of these algorithms is available.
van Paridon, Kjell N; Timmis, Matthew A; Nevison, Charlotte M; Bristow, Matt
2017-01-01
Athletes anticipating sport competition regularly experience distinct emotional and physiological responses as a result of the expected psychosocial and physical stress. Specifically, cortisol, an indicator of hypothalamic-pituitary-adrenal axis activation, prepares the athlete for the psychological and physiological demands of competition. The objective of this meta-analysis is to analyse the magnitude of the anticipatory cortisol response in athletes preparing to participate in sport competition and to examine the influence of gender, level of competition and data collection time. Systematic review with meta-analysis. Four electronic databases were searched to March 2017: PubMed, PsycINFO, SPORTDiscus and Scopus. (1) Athletes participating in real sport competition;(2) salivary cortisol concentration collected before competition in addition to baseline sample(s);(3) original research article published in English language. Data from 25 studies provided 27 effect sizes. A significant anticipatory cortisol response of g=0.85, p<0.001 was identified. Males had a stronger trend for greater cortisol reactivity (g=1.07) than females (g=0.56, p=0.07). Females and athletes competing at international level did not demonstrate a significant anticipatory stress response. There were no significant differences between level of competition, type of sport or time of competition. Meta-regression indicated that the anticipatory cortisol response is greater when assessed closer to the start of competition (Q=6.85, p=0.009). The anticipatory cortisol response before sport competition reflects moderate cortisol reactivity that prepares athletes optimally for the demands of sport competition via the influence on cognitive processes and attentional control. However, both female athletes and international competitors did not demonstrate a significant anticipatory cortisol response, possibly due to differences in appraisal of the stress of sport competition.
78 FR 6120 - Government-Owned Inventions; Availability for Licensing
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-29
..., including immunoprecipitation, western blot analysis, immunohistochemistry, ELISA, etc. Competitive... immunoprecipitation, western blot analysis, immunohistochemistry, ELISA, etc. Competitive Advantages: Binding of a new...
Parallel Algorithms for Image Analysis.
1982-06-01
8217 _ _ _ _ _ _ _ 4. TITLE (aid Subtitle) S. TYPE OF REPORT & PERIOD COVERED PARALLEL ALGORITHMS FOR IMAGE ANALYSIS TECHNICAL 6. PERFORMING O4G. REPORT NUMBER TR-1180...Continue on reverse side it neceesary aid Identlfy by block number) Image processing; image analysis ; parallel processing; cellular computers. 20... IMAGE ANALYSIS TECHNICAL 6. PERFORMING ONG. REPORT NUMBER TR-1180 - 7. AUTHOR(&) S. CONTRACT OR GRANT NUMBER(s) Azriel Rosenfeld AFOSR-77-3271 9
Influence of vein fabric on strain distribution and fold kinematics
NASA Astrophysics Data System (ADS)
Torremans, Koen; Muchez, Philippe; Sintubin, Manuel
2014-05-01
Abundant pre-folding, bedding-parallel fibrous dolomite veins in shale are found associated with the Nkana-Mindola stratiform Cu-Co deposit in the Central African Copperbelt, Zambia. These monomineralic veins extend for several meters along strike, with a fibrous infill orthogonal to low-tortuosity vein walls. Growth morphologies vary from antitaxial with a pronounced median surface to asymmetric syntaxial, always with small but quantifiable growth competition. Subsequently, these veins were folded. In this study, we aim to constrain the kinematic fold mechanism by which strain is accommodated in these veins, estimate paleorheology at time of deformation and investigate the influence of vein fabric on deformation during folding. Finally, the influence of the deformation on known metallogenetic stages is assessed. Various deformation styles are observed, ultimately related to vein attitude across tight to close lower-order, hectometre-scale folds. In fold hinges, at low to average dips, veins are (poly-)harmonically to disharmonically folded as parasitic folds in single or multilayer systems. With increasing distance from the fold hinge, parasitic fold amplitude decreases and asymmetry increases. At high dips in the limbs, low-displacement duplication thrusts of veins at low angles to bedding are abundant. Slickenfibres and slickenlines are sub-perpendicular to fold hinges and shallow-dipping slickenfibre-step lineations are parallel to local fold hinge lines. A dip isogon analysis of reconstructed fold geometries prior to homogeneous shortening reveals type 1B parallel folds for the veins and type 1C for the matrix. Two main deformation mechanisms are identified in folded veins. Firstly, undulatory extinction, subgrains and fluid inclusions planes parallel the fibre long axis, with deformation intensity increasing away from the fold hinges, indicate intracrystalline strain accumulation. Secondly, intergranular deformation through bookshelf rotation of fibres, via collective parallel rotation of fibres and shearing along fibre grain boundaries, is clearly observed under cathodoluminescence. We analysed the internal strain distribution by quantifying simple shear strain caused by deflection of the initially orthogonal fibres relative to layer inclination at a given position across the fold. Shear angle, and thus shear strain, steadily increases towards the limbs away from the fold hinge. Comparison of observed shear strain to theoretical distribution for kinematic mechanisms, amongst other lines of evidence, clearly points to pure flexural flow followed by homogeneous shortening. As flexural flow is not the expected kinematic folding mechanism for competent layers in an incompetent shale matrix, our analysis shows that the internal vein fabric in these dolomite veins can exhibit a first-order influence on folding mechanisms. In addition, quantitative analysis shows that these veins acted as rigid objects with high viscosity contrast relative to the incompetent carbonaceous shale, rather than as semi-passive markers. Later folding-related syn-orogenic veins, intensely mineralised with Cu-Co sulphides, are strongly related to deformation of these pre-folding veins. The high viscosity contrast created by the pre-folding fibrous dolomite veins was therefore essential in creating transient permeability for subsequent mineralising stages in the veining history.
NASA Technical Reports Server (NTRS)
Lou, John; Ferraro, Robert; Farrara, John; Mechoso, Carlos
1996-01-01
An analysis is presented of several factors influencing the performance of a parallel implementation of the UCLA atmospheric general circulation model (AGCM) on massively parallel computer systems. Several modificaitons to the original parallel AGCM code aimed at improving its numerical efficiency, interprocessor communication cost, load-balance and issues affecting single-node code performance are discussed.
Comparing pre- and post-copulatory mate competition using social network analysis in wild crickets
Fisher, David N.; Rodríguez-Muñoz, Rolando
2016-01-01
Sexual selection results from variation in success at multiple stages in the mating process, including competition before and after mating. The relationship between these forms of competition, such as whether they trade-off or reinforce one another, influences the role of sexual selection in evolution. However, the relationship between these 2 forms of competition is rarely quantified in the wild. We used video cameras to observe competition among male field crickets and their matings in the wild. We characterized pre- and post-copulatory competition as 2 networks of competing individuals. Social network analysis then allowed us to determine 1) the effectiveness of precopulatory competition for avoiding postcopulatory competition, 2) the potential for divergent mating strategies, and 3) whether increased postcopulatory competition reduces the apparent reproductive benefits of male promiscuity. We found 1) limited effectiveness of precopulatory competition for avoiding postcopulatory competition; 2) males do not specifically engage in only 1 type of competition; and 3) promiscuous individuals tend to mate with each other, which will tend to reduce variance in reproductive success in the population and highlights the trade-off inherent in mate guarding. Our results provide novel insights into the works of sexual competition in the wild. Furthermore, our study demonstrates the utility of using network analyses to study competitive interactions, even in species lacking obvious social structure. PMID:27174599
Competition Between Electromagnetic Modes in a Free-Electron Maser
1994-02-28
electron perpendicular momentum familiar from gyrotron theory 111). The electron mass is me, initial electron velocity perpendicular and parallel to the...are Q Q2 of zeroth order (-1). Similarly, 48 Y tqfia IIOP --T-V I V s_*/ U- s sI J(93~+ I(*JQL4 8aq 5 Using matrix notation, we can write (i) = (C...disks were in turn electron beam welded to stainless steel flanges. While Kovar was needed to provide a good brazing interface, the mass of the material
High-density digital recording
NASA Technical Reports Server (NTRS)
Kalil, F. (Editor); Buschman, A. (Editor)
1985-01-01
The problems associated with high-density digital recording (HDDR) are discussed. Five independent users of HDDR systems and their problems, solutions, and insights are provided as guidance for other users of HDDR systems. Various pulse code modulation coding techniques are reviewed. An introduction to error detection and correction head optimization theory and perpendicular recording are provided. Competitive tape recorder manufacturers apply all of the above theories and techniques and present their offerings. The methodology used by the HDDR Users Subcommittee of THIC to evaluate parallel HDDR systems is presented.
Matsuura, Kaoru; Jin, Wei Wei; Liu, Hao; Matsumiya, Goro
2018-04-01
The objective of this study was to evaluate the haemodynamic patterns in each anastomosis fashion using a computational fluid dynamic study in a native coronary occlusion model. Fluid dynamic computations were carried out with ANSYS CFX (ANSYS Inc., Canonsburg, PA, USA) software. The incision lengths for parallel and diamond anastomoses were fixed at 2 mm. Native vessels were set to be totally occluded. The diameter of both the native and graft vessels was set to be 2 mm. The inlet boundary condition was set by a sample of the transient time flow measurement which was measured intraoperatively. The diamond anastomosis was observed to reduce flow to the native outlet and increase flow to the bypass outlet; the opposite was observed in the parallel anastomosis. Total energy efficiency was higher in the diamond anastomosis than the parallel anastomosis. Wall shear stress was higher in the diamond anastomosis than in the parallel anastomosis; it was the highest at the top of the outlet. A high oscillatory shear index was observed at the bypass inlet in the parallel anastomosis and at the native inlet in the diamond anastomosis. The diamond sequential anastomosis would be an effective option for multiple sequential bypasses because of the better flow to the bypass outlet than with the parallel anastomosis. However, flow competition should be kept in mind while using the diamond anastomosis for moderately stenotic vessels because of worsened flow to the native outlet. Care should be taken to ensure that the fluid dynamics patterns are optimal and prevent future native and bypass vessel disease progression.
NASA Technical Reports Server (NTRS)
Hsieh, Shang-Hsien
1993-01-01
The principal objective of this research is to develop, test, and implement coarse-grained, parallel-processing strategies for nonlinear dynamic simulations of practical structural problems. There are contributions to four main areas: finite element modeling and analysis of rotational dynamics, numerical algorithms for parallel nonlinear solutions, automatic partitioning techniques to effect load-balancing among processors, and an integrated parallel analysis system.
Microchannel gel electrophoretic separation systems and methods for preparing and using
Herr, Amy E; Singh, Anup K; Throckmorton, Daniel J
2015-02-24
A micro-analytical platform for performing electrophoresis-based immunoassays was developed by integrating photopolymerized cross-linked polyacrylamide gels within a microfluidic device. The microfluidic immunoassays are performed by gel electrophoretic separation and quantifying analyte concentration based upon conventional polyacrylamide gel electrophoresis (PAGE). To retain biological activity of proteins and maintain intact immune complexes, native PAGE conditions were employed. Both direct (non-competitive) and competitive immunoassay formats are demonstrated in microchips for detecting toxins and biomarkers (cytokines, c-reactive protein) in bodily fluids (serum, saliva, oral fluids). Further, a description of gradient gels fabrication is included, in an effort to describe methods we have developed for further optimization of on-chip PAGE immunoassays. The described chip-based PAGE immunoassay method enables immunoassays that are fast (minutes) and require very small amounts of sample (less than a few microliters). Use of microfabricated chips as a platform enables integration, parallel assays, automation and development of portable devices.
Microchannel gel electrophoretic separation systems and methods for preparing and using
Herr, Amy; Singh, Anup K; Throckmorton, Daniel J
2013-09-03
A micro-analytical platform for performing electrophoresis-based immunoassays was developed by integrating photopolymerized cross-linked polyacrylamide gels within a microfluidic device. The microfluidic immunoassays are performed by gel electrophoretic separation and quantifying analyte concentration based upon conventional polyacrylamide gel electrophoresis (PAGE). To retain biological activity of proteins and maintain intact immune complexes, native PAGE conditions were employed. Both direct (non-competitive) and competitive immunoassay formats are demonstrated in microchips for detecting toxins and biomarkers (cytokines, c-reactive protein) in bodily fluids (serum, saliva, oral fluids). Further, a description of gradient gels fabrication is included, in an effort to describe methods we have developed for further optimization of on-chip PAGE immunoassays. The described chip-based PAGE immunoassay method enables immunoassays that are fast (minutes) and require very small amounts of sample (less than a few microliters). Use of microfabricated chips as a platform enables integration, parallel assays, automation and development of portable devices.
The Trojan Lifetime Champions Health Survey: development, validity, and reliability.
Sorenson, Shawn C; Romano, Russell; Scholefield, Robin M; Schroeder, E Todd; Azen, Stanley P; Salem, George J
2015-04-01
Self-report questionnaires are an important method of evaluating lifespan health, exercise, and health-related quality of life (HRQL) outcomes among elite, competitive athletes. Few instruments, however, have undergone formal characterization of their psychometric properties within this population. To evaluate the validity and reliability of a novel health and exercise questionnaire, the Trojan Lifetime Champions (TLC) Health Survey. Descriptive laboratory study. A large National Collegiate Athletic Association Division I university. A total of 63 university alumni (age range, 24 to 84 years), including former varsity collegiate athletes and a control group of nonathletes. Participants completed the TLC Health Survey twice at a mean interval of 23 days with randomization to the paper or electronic version of the instrument. Content validity, feasibility of administration, test-retest reliability, parallel-form reliability between paper and electronic forms, and estimates of systematic and typical error versus differences of clinical interest were assessed across a broad range of health, exercise, and HRQL measures. Correlation coefficients, including intraclass correlation coefficients (ICCs) for continuous variables and κ agreement statistics for ordinal variables, for test-retest reliability averaged 0.86, 0.90, 0.80, and 0.74 for HRQL, lifetime health, recent health, and exercise variables, respectively. Correlation coefficients, again ICCs and κ, for parallel-form reliability (ie, equivalence) between paper and electronic versions averaged 0.90, 0.85, 0.85, and 0.81 for HRQL, lifetime health, recent health, and exercise variables, respectively. Typical measurement error was less than the a priori thresholds of clinical interest, and we found minimal evidence of systematic test-retest error. We found strong evidence of content validity, convergent construct validity with the Short-Form 12 Version 2 HRQL instrument, and feasibility of administration in an elite, competitive athletic population. These data suggest that the TLC Health Survey is a valid and reliable instrument for assessing lifetime and recent health, exercise, and HRQL, among elite competitive athletes. Generalizability of the instrument may be enhanced by additional, larger-scale studies in diverse populations.
Parallel processing in finite element structural analysis
NASA Technical Reports Server (NTRS)
Noor, Ahmed K.
1987-01-01
A brief review is made of the fundamental concepts and basic issues of parallel processing. Discussion focuses on parallel numerical algorithms, performance evaluation of machines and algorithms, and parallelism in finite element computations. A computational strategy is proposed for maximizing the degree of parallelism at different levels of the finite element analysis process including: 1) formulation level (through the use of mixed finite element models); 2) analysis level (through additive decomposition of the different arrays in the governing equations into the contributions to a symmetrized response plus correction terms); 3) numerical algorithm level (through the use of operator splitting techniques and application of iterative processes); and 4) implementation level (through the effective combination of vectorization, multitasking and microtasking, whenever available).
Transmission Index Research of Parallel Manipulators Based on Matrix Orthogonal Degree
NASA Astrophysics Data System (ADS)
Shao, Zhu-Feng; Mo, Jiao; Tang, Xiao-Qiang; Wang, Li-Ping
2017-11-01
Performance index is the standard of performance evaluation, and is the foundation of both performance analysis and optimal design for the parallel manipulator. Seeking the suitable kinematic indices is always an important and challenging issue for the parallel manipulator. So far, there are extensive studies in this field, but few existing indices can meet all the requirements, such as simple, intuitive, and universal. To solve this problem, the matrix orthogonal degree is adopted, and generalized transmission indices that can evaluate motion/force transmissibility of fully parallel manipulators are proposed. Transmission performance analysis of typical branches, end effectors, and parallel manipulators is given to illustrate proposed indices and analysis methodology. Simulation and analysis results reveal that proposed transmission indices possess significant advantages, such as normalized finite (ranging from 0 to 1), dimensionally homogeneous, frame-free, intuitive and easy to calculate. Besides, proposed indices well indicate the good transmission region and relativity to the singularity with better resolution than the traditional local conditioning index, and provide a novel tool for kinematic analysis and optimal design of fully parallel manipulators.
Parallel Event Analysis Under Unix
NASA Astrophysics Data System (ADS)
Looney, S.; Nilsson, B. S.; Oest, T.; Pettersson, T.; Ranjard, F.; Thibonnier, J.-P.
The ALEPH experiment at LEP, the CERN CN division and Digital Equipment Corp. have, in a joint project, developed a parallel event analysis system. The parallel physics code is identical to ALEPH's standard analysis code, ALPHA, only the organisation of input/output is changed. The user may switch between sequential and parallel processing by simply changing one input "card". The initial implementation runs on an 8-node DEC 3000/400 farm, using the PVM software, and exhibits a near-perfect speed-up linearity, reducing the turn-around time by a factor of 8.
ERIC Educational Resources Information Center
Green, Samuel B.; Thompson, Marilyn S.; Levy, Roy; Lo, Wen-Juo
2015-01-01
Traditional parallel analysis (T-PA) estimates the number of factors by sequentially comparing sample eigenvalues with eigenvalues for randomly generated data. Revised parallel analysis (R-PA) sequentially compares the "k"th eigenvalue for sample data to the "k"th eigenvalue for generated data sets, conditioned on"k"-…
Considering Horn's Parallel Analysis from a Random Matrix Theory Point of View.
Saccenti, Edoardo; Timmerman, Marieke E
2017-03-01
Horn's parallel analysis is a widely used method for assessing the number of principal components and common factors. We discuss the theoretical foundations of parallel analysis for principal components based on a covariance matrix by making use of arguments from random matrix theory. In particular, we show that (i) for the first component, parallel analysis is an inferential method equivalent to the Tracy-Widom test, (ii) its use to test high-order eigenvalues is equivalent to the use of the joint distribution of the eigenvalues, and thus should be discouraged, and (iii) a formal test for higher-order components can be obtained based on a Tracy-Widom approximation. We illustrate the performance of the two testing procedures using simulated data generated under both a principal component model and a common factors model. For the principal component model, the Tracy-Widom test performs consistently in all conditions, while parallel analysis shows unpredictable behavior for higher-order components. For the common factor model, including major and minor factors, both procedures are heuristic approaches, with variable performance. We conclude that the Tracy-Widom procedure is preferred over parallel analysis for statistically testing the number of principal components based on a covariance matrix.
Müller, Matthias M; Andersen, Søren K; Hindi Attar, Catherine
2011-11-02
A central controversy in the field of attention is how the brain deals with emotional distractors and to what extent they capture attentional processing resources reflexively due to their inherent significance for guidance of adaptive behavior and survival. Especially, the time course of competitive interactions in early visual areas and whether masking of briefly presented emotional stimuli can inhibit biasing of processing resources in these areas is currently unknown. We recorded frequency-tagged potentials evoked by a flickering target detection task in the foreground of briefly presented emotional or neutral pictures that were followed by a mask in human subjects. We observed greater competition for processing resources in early visual cortical areas with shortly presented emotional relative to neutral pictures ~275 ms after picture offset. This was paralleled by a reduction of target detection rates in trials with emotional pictures ~400 ms after picture offset. Our finding that briefly presented emotional distractors are able to bias attention well after their offset provides evidence for a rather slow feedback or reentrant neural competition mechanism for emotional distractors that continues after the offset of the emotional stimulus.
Computational mechanics analysis tools for parallel-vector supercomputers
NASA Technical Reports Server (NTRS)
Storaasli, O. O.; Nguyen, D. T.; Baddourah, M. A.; Qin, J.
1993-01-01
Computational algorithms for structural analysis on parallel-vector supercomputers are reviewed. These parallel algorithms, developed by the authors, are for the assembly of structural equations, 'out-of-core' strategies for linear equation solution, massively distributed-memory equation solution, unsymmetric equation solution, general eigen-solution, geometrically nonlinear finite element analysis, design sensitivity analysis for structural dynamics, optimization algorithm and domain decomposition. The source code for many of these algorithms is available from NASA Langley.
Cache Locality Optimization for Recursive Programs
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lifflander, Jonathan; Krishnamoorthy, Sriram
We present an approach to optimize the cache locality for recursive programs by dynamically splicing--recursively interleaving--the execution of distinct function invocations. By utilizing data effect annotations, we identify concurrency and data reuse opportunities across function invocations and interleave them to reduce reuse distance. We present algorithms that efficiently track effects in recursive programs, detect interference and dependencies, and interleave execution of function invocations using user-level (non-kernel) lightweight threads. To enable multi-core execution, a program is parallelized using a nested fork/join programming model. Our cache optimization strategy is designed to work in the context of a random work stealing scheduler. Wemore » present an implementation using the MIT Cilk framework that demonstrates significant improvements in sequential and parallel performance, competitive with a state-of-the-art compile-time optimizer for loop programs and a domain- specific optimizer for stencil programs.« less
[Hepatic allopurinol oxidizing enzyme in mice].
Huh, K; Iwata, H; Yamamoto, I
1975-03-01
The relationship between allopurinol oxidizing enzyme and aldehyde oxidase was investaged in mice. The oxidation of both N-methylnicotinamide and allopurinol appears to be catalized by a single enzyme, aldehyde oxidase (aldehyde-oxygen oxidoreductase EC, 1.2.3.1.). This conclusion is based on the following evidence; The postnatal changes of allopurinol and N-methylnicotinamide oxidizing activities were similar during growth and the levels of both activities increased in a parallel fashion upon the attainment of sexual maturity. The rates of loss of the activities of both enzymes by heat denaturation as well as dexamethasone administration were similar. The inhibitors of allopurinol oxidizing enzyme also suppressed N-methylnicotinamide oxidation. Competition of N-methylnicotineamide and allopurinol for oxidation was demonstrated. The rate of increase of the activities in both enzymes was almost parallel during each step of the purification from mouse liver supernatant. It was ascertained that xanthine oxidase in the enzyme preparation does not influence allopurinol oxidation.
A hybrid dynamic harmony search algorithm for identical parallel machines scheduling
NASA Astrophysics Data System (ADS)
Chen, Jing; Pan, Quan-Ke; Wang, Ling; Li, Jun-Qing
2012-02-01
In this article, a dynamic harmony search (DHS) algorithm is proposed for the identical parallel machines scheduling problem with the objective to minimize makespan. First, an encoding scheme based on a list scheduling rule is developed to convert the continuous harmony vectors to discrete job assignments. Second, the whole harmony memory (HM) is divided into multiple small-sized sub-HMs, and each sub-HM performs evolution independently and exchanges information with others periodically by using a regrouping schedule. Third, a novel improvisation process is applied to generate a new harmony by making use of the information of harmony vectors in each sub-HM. Moreover, a local search strategy is presented and incorporated into the DHS algorithm to find promising solutions. Simulation results show that the hybrid DHS (DHS_LS) is very competitive in comparison to its competitors in terms of mean performance and average computational time.
Measurement of the Microwave Refractive Index of Materials Based on Parallel Plate Waveguides
NASA Astrophysics Data System (ADS)
Zhao, F.; Pei, J.; Kan, J. S.; Zhao, Q.
2017-12-01
An electrical field scanning apparatus based on a parallel plate waveguide method is constructed, which collects the amplitude and phase matrices as a function of the relative position. On the basis of such data, a method for calculating the refractive index of the measured wedge samples is proposed in this paper. The measurement and calculation results of different PTFE samples reveal that the refractive index measured by the apparatus is substantially consistent with the refractive index inferred with the permittivity of the sample. The proposed refractive index calculation method proposed in this paper is a competitive method for the characterization of the refractive index of materials with positive refractive index. Since the apparatus and method can be used to measure and calculate arbitrary direction of the microwave propagation, it is believed that both of them can be applied to the negative refractive index materials, such as metamaterials or “left-handed” materials.
Stability of vertical magnetic chains
2017-01-01
A linear stability analysis is performed for a pair of coaxial vertical chains made from permanently magnetized balls under the influence of gravity. While one chain rises from the ground, the other hangs from above, with the remaining ends separated by a gap of prescribed length. Various boundary conditions are considered, as are situations in which the magnetic dipole moments in the two chains are parallel or antiparallel. The case of a single chain attached to the ground is also discussed. The stability of the system is examined with respect to three quantities: the number of balls in each chain, the length of the gap between the chains, and a single dimensionless parameter which embodies the competition between magnetic and gravitational forces. Asymptotic scaling laws involving these parameters are provided. The Hessian matrix is computed in exact form, allowing the critical parameter values at which the system loses stability and the respective eigenmodes to be determined up to machine precision. A comparison with simple experiments for a single chain attached to the ground shows good agreement. PMID:28293135
Stability of vertical magnetic chains
NASA Astrophysics Data System (ADS)
Schönke, Johannes; Fried, Eliot
2017-02-01
A linear stability analysis is performed for a pair of coaxial vertical chains made from permanently magnetized balls under the influence of gravity. While one chain rises from the ground, the other hangs from above, with the remaining ends separated by a gap of prescribed length. Various boundary conditions are considered, as are situations in which the magnetic dipole moments in the two chains are parallel or antiparallel. The case of a single chain attached to the ground is also discussed. The stability of the system is examined with respect to three quantities: the number of balls in each chain, the length of the gap between the chains, and a single dimensionless parameter which embodies the competition between magnetic and gravitational forces. Asymptotic scaling laws involving these parameters are provided. The Hessian matrix is computed in exact form, allowing the critical parameter values at which the system loses stability and the respective eigenmodes to be determined up to machine precision. A comparison with simple experiments for a single chain attached to the ground shows good agreement.
Set as an instance of a real-world visual-cognitive task.
Nyamsuren, Enkhbold; Taatgen, Niels A
2013-01-01
Complex problem solving is often an integration of perceptual processing and deliberate planning. But what balances these two processes, and how do novices differ from experts? We investigate the interplay between these two in the game of SET. This article investigates how people combine bottom-up visual processes and top-down planning to succeed in this game. Using combinatorial and mixed-effect regression analysis of eye-movement protocols and a cognitive model of a human player, we show that SET players deploy both bottom-up and top-down processes in parallel to accomplish the same task. The combination of competition and cooperation of both types of processes is a major factor of success in the game. Finally, we explore strategies players use during the game. Our findings suggest that within-trial strategy shifts can occur without the need of explicit meta-cognitive control, but rather implicitly as a result of evolving memory activations. Copyright © 2012 Cognitive Science Society, Inc.
Does Competition Improve Public School Efficiency? A Spatial Analysis
ERIC Educational Resources Information Center
Misra, Kaustav
2010-01-01
Proponents of educational reform often call for policies to increase competition between schools. It is argued that market forces naturally lead to greater efficiencies, including improved student learning, when schools face competition. In many parts of the country, public schools experience significant competition from private schools; however,…
Parallel Guessing: A Strategy for High-Speed Computation
1984-09-19
for using additional hardware to obtain higher processing speed). In this paper we argue that parallel guessing for image analysis is a useful...from a true solution, or the correctness of a guess, can be readily checked. We review image - analysis algorithms having a parallel guessing or
Mao, Boyan; Wang, Wenxin; Zhao, Zhou; Zhao, Xi; Li, Lanlan; Zhang, Huixia; Liu, Youjun
2016-12-28
During coronary artery bypass grafting (CABG), the ratio of powers of the fundamental frequency and its first harmonic (F0/H1) in fast Fourier transformation (FFT) analysis of the graft's flow waves has been used in the field of evaluation of the patency in anastomosis. But there is no report about using the FFT method to evaluate the magnitude of competitive flow. This study is aiming at exploring the relationship between competitive flow and FFT analysis of the flow waves in left internal mammary artery (LIMA) graft, and finding a new method to evaluate the magnitude of competitive flow. At first, establishing the CABG multiscale models of different stenosis in left anterior descending artery (LAD) to get different magnitude of competitive flows. Then, calculating the models by ANSYS-CFX and getting the flow waves in LIMA. Finally, analyzing the flow waves by FFT method and comparing the FFT results with the magnitude of competitive flow. There is no relationship between competitive flow and F0/H1. As for F0/H2 and F0/H3, they both increase with the reduction of the stenosis in LAD. But the increase of F0/H3 is not obviously enough and it can't identify the significant competitive flow clearly, so it can't be used as the evaluation index. It is found that F0/H2 increases obviously with the increase of the competitive flow and can identify the significant competitive flow. The FFT method can be used in the evaluation of competitive flow and the F0/H2 is the ideal index. High F0/H2 refers to the significant competitive flow. This method can be used during CABG to avoid the risk of competitive flow.
van Paridon, Kjell N; Timmis, Matthew A; Nevison, Charlotte M; Bristow, Matt
2017-01-01
Objective Athletes anticipating sport competition regularly experience distinct emotional and physiological responses as a result of the expected psychosocial and physical stress. Specifically, cortisol, an indicator of hypothalamic-pituitary-adrenal axis activation, prepares the athlete for the psychological and physiological demands of competition. The objective of this meta-analysis is to analyse the magnitude of the anticipatory cortisol response in athletes preparing to participate in sport competition and to examine the influence of gender, level of competition and data collection time. Design Systematic review with meta-analysis. Data sources Four electronic databases were searched to March 2017: PubMed, PsycINFO, SPORTDiscus and Scopus. Eligibility criteria for selecting studies (1) Athletes participating in real sport competition;(2) salivary cortisol concentration collected before competition in addition to baseline sample(s);(3) original research article published in English language. Results Data from 25 studies provided 27 effect sizes. A significant anticipatory cortisol response of g=0.85, p<0.001 was identified. Males had a stronger trend for greater cortisol reactivity (g=1.07) than females (g=0.56, p=0.07). Females and athletes competing at international level did not demonstrate a significant anticipatory stress response. There were no significant differences between level of competition, type of sport or time of competition. Meta-regression indicated that the anticipatory cortisol response is greater when assessed closer to the start of competition (Q=6.85, p=0.009). Summary/conclusion The anticipatory cortisol response before sport competition reflects moderate cortisol reactivity that prepares athletes optimally for the demands of sport competition via the influence on cognitive processes and attentional control. However, both female athletes and international competitors did not demonstrate a significant anticipatory cortisol response, possibly due to differences in appraisal of the stress of sport competition. PMID:29177073
Cache-Oblivious parallel SIMD Viterbi decoding for sequence search in HMMER
2014-01-01
Background HMMER is a commonly used bioinformatics tool based on Hidden Markov Models (HMMs) to analyze and process biological sequences. One of its main homology engines is based on the Viterbi decoding algorithm, which was already highly parallelized and optimized using Farrar’s striped processing pattern with Intel SSE2 instruction set extension. Results A new SIMD vectorization of the Viterbi decoding algorithm is proposed, based on an SSE2 inter-task parallelization approach similar to the DNA alignment algorithm proposed by Rognes. Besides this alternative vectorization scheme, the proposed implementation also introduces a new partitioning of the Markov model that allows a significantly more efficient exploitation of the cache locality. Such optimization, together with an improved loading of the emission scores, allows the achievement of a constant processing throughput, regardless of the innermost-cache size and of the dimension of the considered model. Conclusions The proposed optimized vectorization of the Viterbi decoding algorithm was extensively evaluated and compared with the HMMER3 decoder to process DNA and protein datasets, proving to be a rather competitive alternative implementation. Being always faster than the already highly optimized ViterbiFilter implementation of HMMER3, the proposed Cache-Oblivious Parallel SIMD Viterbi (COPS) implementation provides a constant throughput and offers a processing speedup as high as two times faster, depending on the model’s size. PMID:24884826
Disk-based k-mer counting on a PC
2013-01-01
Background The k-mer counting problem, which is to build the histogram of occurrences of every k-symbol long substring in a given text, is important for many bioinformatics applications. They include developing de Bruijn graph genome assemblers, fast multiple sequence alignment and repeat detection. Results We propose a simple, yet efficient, parallel disk-based algorithm for counting k-mers. Experiments show that it usually offers the fastest solution to the considered problem, while demanding a relatively small amount of memory. In particular, it is capable of counting the statistics for short-read human genome data, in input gzipped FASTQ file, in less than 40 minutes on a PC with 16 GB of RAM and 6 CPU cores, and for long-read human genome data in less than 70 minutes. On a more powerful machine, using 32 GB of RAM and 32 CPU cores, the tasks are accomplished in less than half the time. No other algorithm for most tested settings of this problem and mammalian-size data can accomplish this task in comparable time. Our solution also belongs to memory-frugal ones; most competitive algorithms cannot efficiently work on a PC with 16 GB of memory for such massive data. Conclusions By making use of cheap disk space and exploiting CPU and I/O parallelism we propose a very competitive k-mer counting procedure, called KMC. Our results suggest that judicious resource management may allow to solve at least some bioinformatics problems with massive data on a commodity personal computer. PMID:23679007
Holcomb, Paul S.; Hoffpauir, Brian K.; Hoyson, Mitchell C.; Jackson, Dakota R.; Deerinck, Thomas J.; Marrs, Glenn S.; Dehoff, Marlin; Wu, Jonathan; Ellisman, Mark H.
2013-01-01
Hallmark features of neural circuit development include early exuberant innervation followed by competition and pruning to mature innervation topography. Several neural systems, including the neuromuscular junction and climbing fiber innervation of Purkinje cells, are models to study neural development in part because they establish a recognizable endpoint of monoinnervation of their targets and because the presynaptic terminals are large and easily monitored. We demonstrate here that calyx of Held (CH) innervation of its target, which forms a key element of auditory brainstem binaural circuitry, exhibits all of these characteristics. To investigate CH development, we made the first application of serial block-face scanning electron microscopy to neural development with fine temporal resolution and thereby accomplished the first time series for 3D ultrastructural analysis of neural circuit formation. This approach revealed a growth spurt of added apposed surface area (ASA) >200 μm2/d centered on a single age at postnatal day 3 in mice and an initial rapid phase of growth and competition that resolved to monoinnervation in two-thirds of cells within 3 d. This rapid growth occurred in parallel with an increase in action potential threshold, which may mediate selection of the strongest input as the winning competitor. ASAs of competing inputs were segregated on the cell body surface. These data suggest mechanisms to select “winning” inputs by regional reinforcement of postsynaptic membrane to mediate size and strength of competing synaptic inputs. PMID:23926251
Cashdan, Elizabeth; Gaulin, Steven J C
2016-03-01
Males in many non-monogamous species have larger ranges than females do, a sex difference that has been well documented for decades and seems to be an aspect of male mating competition. Until recently, parallel data for humans have been mostly anecdotal and qualitative, but this is now changing as human behavioral ecologists turn their attention to matters of individual mobility. Sex differences in spatial cognition were among the first accepted psychological sex differences and, like differences in ranging behavior, are documented for a growing set of species. This special issue is dedicated to exploring the possible adaptive links between these cognitive and ranging traits. Multiple hypotheses, at various levels of analysis, are considered. At the functional (ultimate) level, a mating-competition hypothesis suggests that range expansion may augment mating opportunities, and a fertility-and-parental-care hypothesis suggests that range contraction may facilitate offspring provisioning. At a more mechanistic (proximate) level, differences in cue availability may support or inhibit particular sex-specific navigation strategies, and spatial anxiety may usefully inhibit travel that would not justify its costs. Studies in four different cultures-Twe, Tsimane, Yucatec Maya, and Faroese-as well as an experimental study using virtual reality tools are the venue for testing these hypotheses. Our hope is to stimulate more research on the evolutionary and developmental processes responsible for this suite of linked behavioral and cognitive traits.
Application of ply level analysis to flexural wave propagation
NASA Astrophysics Data System (ADS)
Valisetty, R. R.; Rehfield, L. W.
1988-10-01
A brief survey is presented of the shear deformation theories of laminated plates. It indicates that there are certain non-classical influences that affect bending-related behavior in the same way as do the transverse shear stresses. They include bending- and stretching-related section warping and the concomitant non-classical surface parallel stress contributions and the transverse normal stress. A bending theory gives significantly improved performance if these non-classical affects are incorporated. The heterogeneous shear deformations that are characteristic of laminates with highly dissimilar materials, however, require that attention be paid to the modeling of local rotations. In this paper, it is shown that a ply level analysis can be used to model such disparate shear deformations. Here, equilibrium of each layer is analyzed separately. Earlier applications of this analysis include free-edge laminate stresses. It is now extended to the study of flexural wave propagation in laminates. A recently developed homogeneous plate theory is used as a ply level model. Due consideration is given to the non-classical influences and no shear correction factors are introduced extraneously in this theory. The results for the lowest flexural mode of travelling planar harmonic waves indicate that this approach is competitive and yields better results for certain laminates.
Luo, Ruibang; Wong, Yiu-Lun; Law, Wai-Chun; Lee, Lap-Kei; Cheung, Jeanno; Liu, Chi-Man; Lam, Tak-Wah
2014-01-01
This paper reports an integrated solution, called BALSA, for the secondary analysis of next generation sequencing data; it exploits the computational power of GPU and an intricate memory management to give a fast and accurate analysis. From raw reads to variants (including SNPs and Indels), BALSA, using just a single computing node with a commodity GPU board, takes 5.5 h to process 50-fold whole genome sequencing (∼750 million 100 bp paired-end reads), or just 25 min for 210-fold whole exome sequencing. BALSA's speed is rooted at its parallel algorithms to effectively exploit a GPU to speed up processes like alignment, realignment and statistical testing. BALSA incorporates a 16-genotype model to support the calling of SNPs and Indels and achieves competitive variant calling accuracy and sensitivity when compared to the ensemble of six popular variant callers. BALSA also supports efficient identification of somatic SNVs and CNVs; experiments showed that BALSA recovers all the previously validated somatic SNVs and CNVs, and it is more sensitive for somatic Indel detection. BALSA outputs variants in VCF format. A pileup-like SNAPSHOT format, while maintaining the same fidelity as BAM in variant calling, enables efficient storage and indexing, and facilitates the App development of downstream analyses. BALSA is available at: http://sourceforge.net/p/balsa.
The analysis of export commodity competitiveness in Central Java Province at period 2011-2015
NASA Astrophysics Data System (ADS)
Elysi, M. G.; Darsono; Riptanti, E. W.
2018-03-01
This study aims to determine the competitiveness of furniture export in Central Java Province Indonesia in terms of comparative and competitive advantages and to formulate the strategies to enhance the competitiveness of furniture export in Central Java Province. Descriptive analytic method was used for this research. Data used in this research are primary and secondary data. Data were analyzed using RCA (Revealed Comparative Advantage), TSI (Trade Specialization Index) and SOAR (Strength, Opportunity, Aspiration, Result). The results showed that furniture commodity in Central Java Province had strong comparative competitiveness with the value of RCA>1 and had strong competitiveness with positive index values in the range of 0 to 1. Based on SOAR analysis, strategy measures can be formulated, namely maintaining the existing and expanding targeted markets, improving product designs (innovations) and improving raw materials efficiency.
Ferraro Petrillo, Umberto; Roscigno, Gianluca; Cattaneo, Giuseppe; Giancarlo, Raffaele
2018-06-01
Information theoretic and compositional/linguistic analysis of genomes have a central role in bioinformatics, even more so since the associated methodologies are becoming very valuable also for epigenomic and meta-genomic studies. The kernel of those methods is based on the collection of k-mer statistics, i.e. how many times each k-mer in {A,C,G,T}k occurs in a DNA sequence. Although this problem is computationally very simple and efficiently solvable on a conventional computer, the sheer amount of data available now in applications demands to resort to parallel and distributed computing. Indeed, those type of algorithms have been developed to collect k-mer statistics in the realm of genome assembly. However, they are so specialized to this domain that they do not extend easily to the computation of informational and linguistic indices, concurrently on sets of genomes. Following the well-established approach in many disciplines, and with a growing success also in bioinformatics, to resort to MapReduce and Hadoop to deal with 'Big Data' problems, we present KCH, the first set of MapReduce algorithms able to perform concurrently informational and linguistic analysis of large collections of genomic sequences on a Hadoop cluster. The benchmarking of KCH that we provide indicates that it is quite effective and versatile. It is also competitive with respect to the parallel and distributed algorithms highly specialized to k-mer statistics collection for genome assembly problems. In conclusion, KCH is a much needed addition to the growing number of algorithms and tools that use MapReduce for bioinformatics core applications. The software, including instructions for running it over Amazon AWS, as well as the datasets are available at http://www.di-srv.unisa.it/KCH. umberto.ferraro@uniroma1.it. Supplementary data are available at Bioinformatics online.
Microarray-based screening of heat shock protein inhibitors.
Schax, Emilia; Walter, Johanna-Gabriela; Märzhäuser, Helene; Stahl, Frank; Scheper, Thomas; Agard, David A; Eichner, Simone; Kirschning, Andreas; Zeilinger, Carsten
2014-06-20
Based on the importance of heat shock proteins (HSPs) in diseases such as cancer, Alzheimer's disease or malaria, inhibitors of these chaperons are needed. Today's state-of-the-art techniques to identify HSP inhibitors are performed in microplate format, requiring large amounts of proteins and potential inhibitors. In contrast, we have developed a miniaturized protein microarray-based assay to identify novel inhibitors, allowing analysis with 300 pmol of protein. The assay is based on competitive binding of fluorescence-labeled ATP and potential inhibitors to the ATP-binding site of HSP. Therefore, the developed microarray enables the parallel analysis of different ATP-binding proteins on a single microarray. We have demonstrated the possibility of multiplexing by immobilizing full-length human HSP90α and HtpG of Helicobacter pylori on microarrays. Fluorescence-labeled ATP was competed by novel geldanamycin/reblastatin derivatives with IC50 values in the range of 0.5 nM to 4 μM and Z(*)-factors between 0.60 and 0.96. Our results demonstrate the potential of a target-oriented multiplexed protein microarray to identify novel inhibitors for different members of the HSP90 family. Copyright © 2014 Elsevier B.V. All rights reserved.
Learning Style Scales: a valid and reliable questionnaire.
Abdollahimohammad, Abdolghani; Ja'afar, Rogayah
2014-01-01
Learning-style instruments assist students in developing their own learning strategies and outcomes, in eliminating learning barriers, and in acknowledging peer diversity. Only a few psychometrically validated learning-style instruments are available. This study aimed to develop a valid and reliable learning-style instrument for nursing students. A cross-sectional survey study was conducted in two nursing schools in two countries. A purposive sample of 156 undergraduate nursing students participated in the study. Face and content validity was obtained from an expert panel. The LSS construct was established using principal axis factoring (PAF) with oblimin rotation, a scree plot test, and parallel analysis (PA). The reliability of LSS was tested using Cronbach's α, corrected item-total correlation, and test-retest. Factor analysis revealed five components, confirmed by PA and a relatively clear curve on the scree plot. Component strength and interpretability were also confirmed. The factors were labeled as perceptive, solitary, analytic, competitive, and imaginative learning styles. Cronbach's α was >0.70 for all subscales in both study populations. The corrected item-total correlations were >0.30 for the items in each component. The LSS is a valid and reliable inventory for evaluating learning style preferences in nursing students in various multicultural environments.
Evolution of the Max and Mlx networks in animals.
McFerrin, Lisa G; Atchley, William R
2011-01-01
Transcription factors (TFs) are essential for the regulation of gene expression and often form emergent complexes to perform vital roles in cellular processes. In this paper, we focus on the parallel Max and Mlx networks of TFs because of their critical involvement in cell cycle regulation, proliferation, growth, metabolism, and apoptosis. A basic-helix-loop-helix-zipper (bHLHZ) domain mediates the competitive protein dimerization and DNA binding among Max and Mlx network members to form a complex system of cell regulation. To understand the importance of these network interactions, we identified the bHLHZ domain of Max and Mlx network proteins across the animal kingdom and carried out several multivariate statistical analyses. The presence and conservation of Max and Mlx network proteins in animal lineages stemming from the divergence of Metazoa indicate that these networks have ancient and essential functions. Phylogenetic analysis of the bHLHZ domain identified clear relationships among protein families with distinct points of radiation and divergence. Multivariate discriminant analysis further isolated specific amino acid changes within the bHLHZ domain that classify proteins, families, and network configurations. These analyses on Max and Mlx network members provide a model for characterizing the evolution of TFs involved in essential networks.
ERIC Educational Resources Information Center
Baumann, Chris; Hamin
2011-01-01
A nation's culture, competitiveness and economic performance explain academic performance. Partial Least Squares (PLS) testing of 2252 students shows culture affects competitiveness and academic performance. Culture and economic performance each explain 32%; competitiveness 36%. The model predicts academic performance when culture, competitiveness…
1986-12-01
17 III. Analysis of Parallel Design ................................................ 18 Parallel Abstract Data ...Types ........................................... 18 Abstract Data Type .................................................. 19 Parallel ADT...22 Data -Structure Design ........................................... 23 Object-Oriented Design
Kaplan, Ian; Denno, Robert F
2007-10-01
The importance of interspecific competition is a highly controversial and unresolved issue for community ecology in general, and for phytophagous insects in particular. Recent advancements, however, in our understanding of indirect (plant- and enemy-mediated) interactions challenge the historical paradigms of competition. Thus, in the context of this rapidly developing field, we re-evaluate the evidence for interspecific competition in phytophagous insects using a meta-analysis of published studies. Our analysis is specifically designed to test the assumptions underlying traditional competition theory, namely that competitive interactions are symmetrical, necessitate spatial and temporal co-occurrence, and increase in intensity as the density, phylogenetic similarity, and niche overlap of competing species increase. Despite finding frequent evidence for competition, we found very little evidence that plant-feeding insects conform to theoretical predictions for interspecific competition. Interactions were highly asymmetrical, similar in magnitude within vs. between feeding guilds (chewers vs. sap-feeders), and were unaffected by the quantity of resources removed (% defoliation). There was mixed support for the effects of phylogeny, spatial/temporal separation, and the relative strength of intra- vs. interspecific competition. Clearly, a new paradigm that accounts for indirect interactions and facilitation is required to describe how interspecific competition contributes to the organization of phytophagous insect communities, and perhaps to other plant and animal communities as well.
Programming Probabilistic Structural Analysis for Parallel Processing Computer
NASA Technical Reports Server (NTRS)
Sues, Robert H.; Chen, Heh-Chyun; Twisdale, Lawrence A.; Chamis, Christos C.; Murthy, Pappu L. N.
1991-01-01
The ultimate goal of this research program is to make Probabilistic Structural Analysis (PSA) computationally efficient and hence practical for the design environment by achieving large scale parallelism. The paper identifies the multiple levels of parallelism in PSA, identifies methodologies for exploiting this parallelism, describes the development of a parallel stochastic finite element code, and presents results of two example applications. It is demonstrated that speeds within five percent of those theoretically possible can be achieved. A special-purpose numerical technique, the stochastic preconditioned conjugate gradient method, is also presented and demonstrated to be extremely efficient for certain classes of PSA problems.
Motion capability analysis of a quadruped robot as a parallel manipulator
NASA Astrophysics Data System (ADS)
Yu, Jingjun; Lu, Dengfeng; Zhang, Zhongxiang; Pei, Xu
2014-12-01
This paper presents the forward and inverse displacement analysis of a quadruped robot MANA as a parallel manipulator in quadruple stance phase, which is used to obtain the workspace and control the motion of the body. The robot MANA designed on the basis of the structure of quadruped mammal is able to not only walk and turn in the uneven terrain, but also accomplish various manipulating tasks as a parallel manipulator in quadruple stance phase. The latter will be the focus of this paper, however. For this purpose, the leg kinematics is primarily analyzed, which lays the foundation on the gait planning in terms of locomotion and body kinematics analysis as a parallel manipulator. When all four feet of the robot contact on the ground, by assuming there is no slipping at the feet, each contacting point is treated as a passive spherical joint and the kinematic model of parallel manipulator is established. The method for choosing six non-redundant actuated joints for the parallel manipulator from all twelve optional joints is elaborated. The inverse and forward displacement analysis of the parallel manipulator is carried out using the method of coordinate transformation. Finally, based on the inverse and forward kinematic model, two issues on obtaining the reachable workspace of parallel manipulator and planning the motion of the body are implemented and verified by ADAMS simulation.
Disciplinary competitiveness analysis in international stomatology education.
Wen, Ping; Hong, Xiao; Zhu, Lu; Zhang, Linglin; Gu, Xuekui; Gao, Zhihua; Chen, Qianming
2013-11-01
With economic and cultural globalization, the trend of globalization of higher education becomes inevitable. Using the concept of competitiveness, the authors established a principal component analysis (PCA) model to examine disciplinary competitiveness in stomatology of various higher education institutions worldwide. A total of forty-four universities entered the final list according to these calculations. Possible reasons for their selection were explored and explained at macro and micro levels. The authors further accessed various sources of data and summarized several suggestions for enhancing disciplinary competitiveness for other universities in pursuit of promoting their position in the global spectrum.
Mayer, Melanie G.; Rödelsperger, Christian; Witte, Hanh; Riebesell, Metta; Sommer, Ralf J.
2015-01-01
Many nematodes form dauer larvae when exposed to unfavorable conditions, representing an example of phenotypic plasticity and a major survival and dispersal strategy. In Caenorhabditis elegans, the regulation of dauer induction is a model for pheromone, insulin, and steroid-hormone signaling. Recent studies in Pristionchus pacificus revealed substantial natural variation in various aspects of dauer development, i.e. pheromone production and sensing and dauer longevity and fitness. One intriguing example is a strain from Ohio, having extremely long-lived dauers associated with very high fitness and often forming the most dauers in response to other strains´ pheromones, including the reference strain from California. While such examples have been suggested to represent intraspecific competition among strains, the molecular mechanisms underlying these dauer-associated patterns are currently unknown. We generated recombinant-inbred-lines between the Californian and Ohioan strains and used quantitative-trait-loci analysis to investigate the molecular mechanism determining natural variation in dauer development. Surprisingly, we discovered that the orphan gene dauerless controls dauer formation by copy number variation. The Ohioan strain has one dauerless copy causing high dauer formation, whereas the Californian strain has two copies, resulting in strongly reduced dauer formation. Transgenic animals expressing multiple copies do not form dauers. dauerless is exclusively expressed in CAN neurons, and both CAN ablation and dauerless mutations increase dauer formation. Strikingly, dauerless underwent several duplications and acts in parallel or downstream of steroid-hormone signaling but upstream of the nuclear-hormone-receptor daf-12. We identified the novel or fast-evolving gene dauerless as inhibitor of dauer development. Our findings reveal the importance of gene duplications and copy number variations for orphan gene function and suggest daf-12 as major target for dauer regulation. We discuss the consequences of the novel vs. fast-evolving nature of orphans for the evolution of developmental networks and their role in natural variation and intraspecific competition. PMID:26087034
Mayer, Melanie G; Rödelsperger, Christian; Witte, Hanh; Riebesell, Metta; Sommer, Ralf J
2015-06-01
Many nematodes form dauer larvae when exposed to unfavorable conditions, representing an example of phenotypic plasticity and a major survival and dispersal strategy. In Caenorhabditis elegans, the regulation of dauer induction is a model for pheromone, insulin, and steroid-hormone signaling. Recent studies in Pristionchus pacificus revealed substantial natural variation in various aspects of dauer development, i.e. pheromone production and sensing and dauer longevity and fitness. One intriguing example is a strain from Ohio, having extremely long-lived dauers associated with very high fitness and often forming the most dauers in response to other strains' pheromones, including the reference strain from California. While such examples have been suggested to represent intraspecific competition among strains, the molecular mechanisms underlying these dauer-associated patterns are currently unknown. We generated recombinant-inbred-lines between the Californian and Ohioan strains and used quantitative-trait-loci analysis to investigate the molecular mechanism determining natural variation in dauer development. Surprisingly, we discovered that the orphan gene dauerless controls dauer formation by copy number variation. The Ohioan strain has one dauerless copy causing high dauer formation, whereas the Californian strain has two copies, resulting in strongly reduced dauer formation. Transgenic animals expressing multiple copies do not form dauers. dauerless is exclusively expressed in CAN neurons, and both CAN ablation and dauerless mutations increase dauer formation. Strikingly, dauerless underwent several duplications and acts in parallel or downstream of steroid-hormone signaling but upstream of the nuclear-hormone-receptor daf-12. We identified the novel or fast-evolving gene dauerless as inhibitor of dauer development. Our findings reveal the importance of gene duplications and copy number variations for orphan gene function and suggest daf-12 as major target for dauer regulation. We discuss the consequences of the novel vs. fast-evolving nature of orphans for the evolution of developmental networks and their role in natural variation and intraspecific competition.
NASA Technical Reports Server (NTRS)
Nicol, David; Fujimoto, Richard
1992-01-01
This paper surveys topics that presently define the state of the art in parallel simulation. Included in the tutorial are discussions on new protocols, mathematical performance analysis, time parallelism, hardware support for parallel simulation, load balancing algorithms, and dynamic memory management for optimistic synchronization.
Jia, Cheng; Hu, Yu; Kelly, Derek; Kim, Junhyong; Li, Mingyao; Zhang, Nancy R
2017-11-02
Recent technological breakthroughs have made it possible to measure RNA expression at the single-cell level, thus paving the way for exploring expression heterogeneity among individual cells. Current single-cell RNA sequencing (scRNA-seq) protocols are complex and introduce technical biases that vary across cells, which can bias downstream analysis without proper adjustment. To account for cell-to-cell technical differences, we propose a statistical framework, TASC (Toolkit for Analysis of Single Cell RNA-seq), an empirical Bayes approach to reliably model the cell-specific dropout rates and amplification bias by use of external RNA spike-ins. TASC incorporates the technical parameters, which reflect cell-to-cell batch effects, into a hierarchical mixture model to estimate the biological variance of a gene and detect differentially expressed genes. More importantly, TASC is able to adjust for covariates to further eliminate confounding that may originate from cell size and cell cycle differences. In simulation and real scRNA-seq data, TASC achieves accurate Type I error control and displays competitive sensitivity and improved robustness to batch effects in differential expression analysis, compared to existing methods. TASC is programmed to be computationally efficient, taking advantage of multi-threaded parallelization. We believe that TASC will provide a robust platform for researchers to leverage the power of scRNA-seq. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.
Jia, Cheng; Hu, Yu; Kelly, Derek; Kim, Junhyong
2017-01-01
Abstract Recent technological breakthroughs have made it possible to measure RNA expression at the single-cell level, thus paving the way for exploring expression heterogeneity among individual cells. Current single-cell RNA sequencing (scRNA-seq) protocols are complex and introduce technical biases that vary across cells, which can bias downstream analysis without proper adjustment. To account for cell-to-cell technical differences, we propose a statistical framework, TASC (Toolkit for Analysis of Single Cell RNA-seq), an empirical Bayes approach to reliably model the cell-specific dropout rates and amplification bias by use of external RNA spike-ins. TASC incorporates the technical parameters, which reflect cell-to-cell batch effects, into a hierarchical mixture model to estimate the biological variance of a gene and detect differentially expressed genes. More importantly, TASC is able to adjust for covariates to further eliminate confounding that may originate from cell size and cell cycle differences. In simulation and real scRNA-seq data, TASC achieves accurate Type I error control and displays competitive sensitivity and improved robustness to batch effects in differential expression analysis, compared to existing methods. TASC is programmed to be computationally efficient, taking advantage of multi-threaded parallelization. We believe that TASC will provide a robust platform for researchers to leverage the power of scRNA-seq. PMID:29036714
DOE Office of Scientific and Technical Information (OSTI.GOV)
Davis, Zachary; Gac, Frank; Nacht, Michael
Lawrence Livermore National Laboratory and National Intelligence University convened a group of business experts to examine parallels between S&T competition in the marketplace and science and technology intelligence (S&TI). The experts identified the centrality of people — individuals and connected groups — to the successful development and application of latent S&T capabilities. People may indeed be more important to recognizing S&T potential than deep knowledge of any particular technology. This report explores the significance of this key insight for S&TI.
l-Glutamine as a Substrate for l-Asparaginase from Serratia marcescens
Novak, Edward K.; Phillips, Arthur W.
1974-01-01
l-Asparaginase from Serratia marcescens was found to hydrolyze l-glutamine at 5% of the rate of l-asparagine hydrolysis. The ratio of the two activities did not change through several stages of purification, anionic and cationic polyacrylamide disk gel electrophoresis, and partial thermal inactivation. The two activities had parallel blood clearance rates in mice. l-glutamine was found to be a competitive inhibitor of l-asparagine hydrolysis. A separate l-glutaminase enzyme free of l-asparaginase activity was separated by diethylaminoethyl-cellulose chromatography. PMID:4590479
Searching for an Axis-Parallel Shoreline
NASA Astrophysics Data System (ADS)
Langetepe, Elmar
We are searching for an unknown horizontal or vertical line in the plane under the competitive framework. We design a framework for lower bounds on all cyclic and monotone strategies that result in two-sequence functionals. For optimizing such functionals we apply a method that combines two main paradigms. The given solution shows that the combination method is of general interest. Finally, we obtain the current best strategy and can prove that this is the best strategy among all cyclic and monotone strategies which is a main step toward a lower bound construction.
77 FR 46717 - Export Trade Certificate of Review
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-06
... Competition and Economic Analysis (``OCEA'') of the International Trade Administration, Department of Commerce... and Economic Analysis, International Trade Administration, (202) 482-5131 (this is not a toll-free... of Competition and Economic Analysis. [FR Doc. 2012-19117 Filed 8-3-12; 8:45 am] BILLING CODE 3510-DR...
Effects of competition outcome on testosterone concentrations in humans: An updated meta-analysis.
Geniole, Shawn N; Bird, Brian M; Ruddick, Erika L; Carré, Justin M
2017-06-01
A contribution to a special issue on Hormones and Human Competition. Since Archer's (2006) influential meta-analysis, there has been a major increase in the number of studies investigating the effect of competition outcome on testosterone reactivity patterns in humans. Despite this increased research output, there remains debate as to whether competition outcome modulates testosterone concentrations. The present paper examines this question using a meta-analytic approach including papers published over the last 35years. Moreover, it provides the first meta-analytic estimate of the effect of competition outcome on testosterone concentrations in women. Results from a meta-analysis involving 60 effect sizes and >2500 participants indicated that winners of a competition demonstrated a larger increase in testosterone concentrations relative to losers (D=0.20)-an effect that was highly heterogeneous. This 'winner-loser' effect was most robust in studies conducted outside the lab (e.g., in sport venues) (D=0.43); for studies conducted in the lab, the effect of competition outcome on testosterone reactivity patterns was relatively weak (D=0.08), and only found in studies of men (D=0.15; in women: D=-0.04). Further, the 'winner-loser' effect was stronger among studies in which pre-competition testosterone was sampled earlier than (D=0.38, after trim and fill correction) rather than within (D=0.09) 10min of the start of the competition. Therefore, these results also provide important insight regarding study design and methodology, and will be a valuable resource for researchers conducting subsequent studies on the 'winner loser' effect. Copyright © 2016 Elsevier Inc. All rights reserved.
Heart rate variability and pre-competitive anxiety in BMX discipline.
Mateo, Manuel; Blasco-Lafarga, Cristina; Martínez-Navarro, Ignacio; Guzmán, José F; Zabala, Mikel
2012-01-01
Altered neural mechanisms implying autonomic functioning have been described related to anxiety. Pre-competitive stress may be considered as an anxiety-state associated with disorders (i.e. somatic and cognitive alterations, and self-confidence worsening) that severely impair sport performance, conditioning short-lasting strength-related disciplines like BMX. From the psychological perspective, coaches use questionnaires like CSAI-2R to identify these alterations. However, with the emergence of psycho-physiological and non-linear approaches, recent studies suggest that HRV analysis provides a non-invasive tool to assess them. Hence, our purpose was to analyze how BMX competition affects subjective perception of anxiety, and if this emotional alteration is reflected in HR dynamics, analyzed both linear and nonlinearly, exploring the evolution of this relationship in a 2-day competition. Eleven male athletes from the BMX Spanish National Team were assessed from baseline HRV the morning of a training session (rT) and on two successive days of competition (rC1 and rC2), repeating HRV recording with CSAI-2R 20 min prior to training (aT) and competition (pre-competitive: aC1 and aC2). Repeated measures MANOVA showed significant vagal slow-down responses in aC1 and aC2 comparing not only with aT, but also comparing with rT, rC1 and rC2, coinciding with significant greater scores for the somatic and cognitive anxiety (SA and CA) in aC1 and aC2 versus aT. Pearson analysis showed a large and positive correlation between α1 and SA in C1, and close to it between SampEn and CA in aC2; both were confirmed by Bland-Altman chart analysis. Our results confirm that HRV analysis provide a complementary tool to assess competitive pressure.
Parallel processing considerations for image recognition tasks
NASA Astrophysics Data System (ADS)
Simske, Steven J.
2011-01-01
Many image recognition tasks are well-suited to parallel processing. The most obvious example is that many imaging tasks require the analysis of multiple images. From this standpoint, then, parallel processing need be no more complicated than assigning individual images to individual processors. However, there are three less trivial categories of parallel processing that will be considered in this paper: parallel processing (1) by task; (2) by image region; and (3) by meta-algorithm. Parallel processing by task allows the assignment of multiple workflows-as diverse as optical character recognition [OCR], document classification and barcode reading-to parallel pipelines. This can substantially decrease time to completion for the document tasks. For this approach, each parallel pipeline is generally performing a different task. Parallel processing by image region allows a larger imaging task to be sub-divided into a set of parallel pipelines, each performing the same task but on a different data set. This type of image analysis is readily addressed by a map-reduce approach. Examples include document skew detection and multiple face detection and tracking. Finally, parallel processing by meta-algorithm allows different algorithms to be deployed on the same image simultaneously. This approach may result in improved accuracy.
U.S. Clean Energy Hydrogen and Fuel Cell Technologies: A Competitiveness Analysis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fullenkamp, Patrick; Holody, Diane; James, Brian
The objectives of this project are a 1) Global Competitiveness Analysis of hydrogen and fuel cell systems and components manufactured including 700 bar compressed hydrogen storage system in the U.S., Europe, Asia, and other key areas to be identified to determine the global cost leaders, the best current manufacturing processes, the key factors determining competitiveness, and the potential means of cost reductions; and an 2) Analysis to assess the status of global hydrogen and fuel cell markets. The analysis of units, megawatts by country and by application will focus on polymer electrolyte membrane (PEM) fuel cell systems (automotive and stationary).
Pamies-Aubalat, Lidia; Quiles-Marcos, Yolanda; Núñez-Núñez, Rosa M
2013-12-01
This study examined the Dieting Peer Competitiveness Scale; it is an instrument for evaluating this social comparison in young people. This instrumental study has two aims: The objective of the first aim was to present preliminary psychometric data from the Spanish version of the Dieting Peer Competitiveness Scale, including statistical item analysis, research about this instrument's internal structure, and a reliability analysis, from a sample of 1067 secondary school adolescents. The second objective of the study corresponds to confirmatory factor analysis of the scale's internal structure, as well as analysis for evidence of validity from a sample of 1075 adolescents.
1984-09-01
Research Study Number Three. In 1982, Mr. Edward Brost , then a graduate student at AFIT, completed a thesis which further analyzed the effects of sole...task, Brost formulated three research questions. They are as follows: 1. Is there a reduction in replenishment spare parts prices when competition is...analysis, Brost made three significant conclusions. They are: 1. The introduction of competition into the replenishment spare parts acquisition process
Parallel-vector solution of large-scale structural analysis problems on supercomputers
NASA Technical Reports Server (NTRS)
Storaasli, Olaf O.; Nguyen, Duc T.; Agarwal, Tarun K.
1989-01-01
A direct linear equation solution method based on the Choleski factorization procedure is presented which exploits both parallel and vector features of supercomputers. The new equation solver is described, and its performance is evaluated by solving structural analysis problems on three high-performance computers. The method has been implemented using Force, a generic parallel FORTRAN language.
Parallel auto-correlative statistics with VTK.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pebay, Philippe Pierre; Bennett, Janine Camille
2013-08-01
This report summarizes existing statistical engines in VTK and presents both the serial and parallel auto-correlative statistics engines. It is a sequel to [PT08, BPRT09b, PT09, BPT09, PT10] which studied the parallel descriptive, correlative, multi-correlative, principal component analysis, contingency, k-means, and order statistics engines. The ease of use of the new parallel auto-correlative statistics engine is illustrated by the means of C++ code snippets and algorithm verification is provided. This report justifies the design of the statistics engines with parallel scalability in mind, and provides scalability and speed-up analysis results for the autocorrelative statistics engine.
Introducing parallelism to histogramming functions for GEM systems
NASA Astrophysics Data System (ADS)
Krawczyk, Rafał D.; Czarski, Tomasz; Kolasinski, Piotr; Pozniak, Krzysztof T.; Linczuk, Maciej; Byszuk, Adrian; Chernyshova, Maryna; Juszczyk, Bartlomiej; Kasprowicz, Grzegorz; Wojenski, Andrzej; Zabolotny, Wojciech
2015-09-01
This article is an assessment of potential parallelization of histogramming algorithms in GEM detector system. Histogramming and preprocessing algorithms in MATLAB were analyzed with regard to adding parallelism. Preliminary implementation of parallel strip histogramming resulted in speedup. Analysis of algorithms parallelizability is presented. Overview of potential hardware and software support to implement parallel algorithm is discussed.
Mascia, Daniele; Di Vincenzo, Fausto; Cicchetti, Americo
2012-05-01
Policymakers stimulate competition in universalistic health-care systems while encouraging the formation of service provision networks among hospital organizations. This article addresses a gap in the extant literature by empirically analyzing simultaneous collaboration and competition between hospitals within the Italian National Health Service, where important procompetition reforms have been implemented. To explore how rising competition between hospitals relates to their propensity to collaborate with other local providers. Longitudinal data on interhospital collaboration and competition collected in an Italian region from 2003 to 2007 are analyzed. Social network analysis techniques are applied to study the structure and dynamics of interhospital collaboration. Negative binomial regressions are employed to explore how interhospital competition relates to the collaborative network over time. Competition among providers does not hinder interhospital collaboration. Collaboration is primarily local, with resource complementarity and differentials in the volume of activity and hospital performance explaining the propensity to collaborate. Formation of collaborative networks among hospitals is not hampered by reforms aimed at fostering market forces. Because procompetition reforms elicit peculiar forms of managed competition in universalistic health systems, studies are needed to clarify whether the positive association between interhospital competition and collaboration can be generalized to other health-care settings. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Navara, Kristen J.
2016-01-01
Competition between conspecifics during the breeding season can result in behavioural and physiological programming of offspring via maternal effects. For birds, in which maternal effects are best studied, it has been claimed that exposure to increased competition causes greater deposition of testosterone into egg yolks, which creates faster growing, more aggressive offspring; such traits are thought to be beneficial for high-competition environments. Nevertheless, not all species show a positive relationship between competitive interactions and yolk testosterone, and an explanation for this interspecific variation is lacking. We here test if the magnitude and direction of maternal testosterone allocated to eggs in response to competition can be explained by life-history traits while accounting for phylogenetic relationships. We performed a meta-analysis relating effect size of yolk testosterone response to competition with species coloniality, nest type, parental effort and mating type. We found that effect size was moderated by coloniality and nest type; colonial species and those with open nests allocate less testosterone to eggs when in more competitive environments. Applying a life-history perspective helps contextualize studies showing little or negative responses of yolk testosterone to competition and improves our understanding of how variation in this maternal effect may have evolved. PMID:28018636
Validity and factor structure of the bodybuilding dependence scale.
Smith, D; Hale, B
2004-04-01
To investigate the factor structure, validity, and reliability of the bodybuilding dependence scale and to investigate differences in bodybuilding dependence between men and women and competitive and non-competitive bodybuilders. Seventy two male competitive bodybuilders, 63 female competitive bodybuilders, 87 male non-competitive bodybuilders, and 63 non-competitive female bodybuilders completed the bodybuilding dependence scale (BDS), the exercise dependence questionnaire (EDQ), and the muscle dysmorphia inventory (MDI). Confirmatory factor analysis of the BDS supported a three factor model of bodybuilding dependence, consisting of social dependence, training dependence, and mastery dependence (Q = 3.16, CFI = 0.98, SRMR = 0.04). Internal reliability of all three subscales was high (Cronbach's alpha = 0.92, 0.92, and 0.93 respectively). Significant (p<0.001) and moderate correlations were found between all BDS and MDI subscales, and between five of the eight EDQ subscales. A multivariate analysis of covariance, with univariate F tests and Tukey HSD tests, revealed that both male and female competitive bodybuilders scored significantly (p<0.05) higher on all three BDS subscales than the male and female non-competitive bodybuilders. However, there were no significant sex differences on any of the BDS subscales (p>0.05). The three factor BDS appears to be a reliable and valid measure of bodybuilding dependence. Symptoms of bodybuilding dependence are more prevalent in competitive bodybuilders than non-competitive ones, but there are no significant sex differences in bodybuilding dependence.
Reliability Modeling Methodology for Independent Approaches on Parallel Runways Safety Analysis
NASA Technical Reports Server (NTRS)
Babcock, P.; Schor, A.; Rosch, G.
1998-01-01
This document is an adjunct to the final report An Integrated Safety Analysis Methodology for Emerging Air Transport Technologies. That report presents the results of our analysis of the problem of simultaneous but independent, approaches of two aircraft on parallel runways (independent approaches on parallel runways, or IAPR). This introductory chapter presents a brief overview and perspective of approaches and methodologies for performing safety analyses for complex systems. Ensuing chapter provide the technical details that underlie the approach that we have taken in performing the safety analysis for the IAPR concept.
Interactive Parallel Data Analysis within Data-Centric Cluster Facilities using the IPython Notebook
NASA Astrophysics Data System (ADS)
Pascoe, S.; Lansdowne, J.; Iwi, A.; Stephens, A.; Kershaw, P.
2012-12-01
The data deluge is making traditional analysis workflows for many researchers obsolete. Support for parallelism within popular tools such as matlab, IDL and NCO is not well developed and rarely used. However parallelism is necessary for processing modern data volumes on a timescale conducive to curiosity-driven analysis. Furthermore, for peta-scale datasets such as the CMIP5 archive, it is no longer practical to bring an entire dataset to a researcher's workstation for analysis, or even to their institutional cluster. Therefore, there is an increasing need to develop new analysis platforms which both enable processing at the point of data storage and which provides parallelism. Such an environment should, where possible, maintain the convenience and familiarity of our current analysis environments to encourage curiosity-driven research. We describe how we are combining the interactive python shell (IPython) with our JASMIN data-cluster infrastructure. IPython has been specifically designed to bridge the gap between the HPC-style parallel workflows and the opportunistic curiosity-driven analysis usually carried out using domain specific languages and scriptable tools. IPython offers a web-based interactive environment, the IPython notebook, and a cluster engine for parallelism all underpinned by the well-respected Python/Scipy scientific programming stack. JASMIN is designed to support the data analysis requirements of the UK and European climate and earth system modeling community. JASMIN, with its sister facility CEMS focusing the earth observation community, has 4.5 PB of fast parallel disk storage alongside over 370 computing cores provide local computation. Through the IPython interface to JASMIN, users can make efficient use of JASMIN's multi-core virtual machines to perform interactive analysis on all cores simultaneously or can configure IPython clusters across multiple VMs. Larger-scale clusters can be provisioned through JASMIN's batch scheduling system. Outputs can be summarised and visualised using the full power of Python's many scientific tools, including Scipy, Matplotlib, Pandas and CDAT. This rich user experience is delivered through the user's web browser; maintaining the interactive feel of a workstation-based environment with the parallel power of a remote data-centric processing facility.
Determinats of Interregional Competion of Subjects of Russian Federation
NASA Astrophysics Data System (ADS)
Gaisin, R. I.; Latypov, R. A.; Gaisin, I. T.; Kubyshkina, E. N.; Hayaleeva, A. D.
2018-05-01
In the article, problems of the analysis of competitiveness of subjects of the Russian Federation at the level of the national market of the country are considered. For a research of indicators and dynamics of competitiveness of certain territorial subjects of the Russian Federation, the methodology and tools of the theory of the interregional markets of the country developed by one of authors of epy article are used. On the basis of the known theory of competitiveness of M. Porter, the main directions of an increase of the competition in the interregional market of Russia are offered. Keywords: competitiveness, competitiveness determinants, interregional competition, interregional markets of the country
Merlo, Caitlin L; Olsen, Emily O'Malley; Galic, Mara; Brener, Nancy D
2014-04-24
Most students in grades kindergarten through 12 have access to foods and beverages during the school day outside the federal school meal programs, which are called competitive foods. At the time of this study, competitive foods were subject to minimal federal nutrition standards, but states could implement additional standards. Our analysis examined the association between school nutrition practices and alignment of state policies with Institute of Medicine recommendations (IOM Standards). For this analysis we used data from the Centers for Disease Control and Prevention's (CDC's) report, Competitive Foods and Beverages in US Schools: A State Policy Analysis and CDC's 2010 School Health Profiles (Profiles) survey to examine descriptive associations between state policies for competitive foods and school nutrition practices. Access to chocolate candy, soda pop, sports drinks, and caffeinated foods or beverages was lower in schools in states with policies more closely aligned with IOM Standards. No association was found for access to fruits or nonfried vegetables. Schools in states with policies more closely aligned with the IOM Standards reported reduced access to less healthful competitive foods. Encouraging more schools to follow these standards will help create healthier school environments and may help promote healthy eating among US children.
Yun, Jian; Shang, Song-Chao; Wei, Xiao-Dan; Liu, Shuang; Li, Zhi-Jie
2016-01-01
Language is characterized by both ecological properties and social properties, and competition is the basic form of language evolution. The rise and decline of one language is a result of competition between languages. Moreover, this rise and decline directly influences the diversity of human culture. Mathematics and computer modeling for language competition has been a popular topic in the fields of linguistics, mathematics, computer science, ecology, and other disciplines. Currently, there are several problems in the research on language competition modeling. First, comprehensive mathematical analysis is absent in most studies of language competition models. Next, most language competition models are based on the assumption that one language in the model is stronger than the other. These studies tend to ignore cases where there is a balance of power in the competition. The competition between two well-matched languages is more practical, because it can facilitate the co-development of two languages. A third issue with current studies is that many studies have an evolution result where the weaker language inevitably goes extinct. From the integrated point of view of ecology and sociology, this paper improves the Lotka-Volterra model and basic reaction-diffusion model to propose an "ecology-society" computational model for describing language competition. Furthermore, a strict and comprehensive mathematical analysis was made for the stability of the equilibria. Two languages in competition may be either well-matched or greatly different in strength, which was reflected in the experimental design. The results revealed that language coexistence, and even co-development, are likely to occur during language competition.
Numerical modelling of the formation of fibrous bedding-parallel veins
NASA Astrophysics Data System (ADS)
Torremans, Koen; Muchez, Philippe; Sintubin, Manuel
2014-05-01
Bedding-parallel veins with a fibrous infill oriented orthogonal to the vein wall, are often observed in fine-grained metasedimentary sequences. Several mechanisms have been proposed for their formation, mostly with respect to effects of fluid overpressures and anisotropy of the host-rock fabric in order to explain the inferred extensional failure with sub-vertical opening. Abundant pre-folding, bedding-parallel fibrous dolomite veins are found associated with the Nkana-Mindola stratiform Cu-Co deposit in Zambia. The goal of this study is to better understand the formation mechanisms of these veins and to explain their particular spatial and thickness distribution, with respect to failure of transversely isotropic rocks. The spatial distribution and thickness variation of these veins was quantified during a field campaign in thirteen line transects perpendicular to undeformed veins in underground crosscuts. The fibrous dolomite veins studied are not related to lithological contrasts, but to a strong bedding-parallel shaly fabric, typical for the black shale facies of the Copperbelt Orebody Member. The host rock can hence be considered as transversely isotropic. Growth morphologies vary from antitaxial with a pronounced median surface to asymmetric syntaxial, always with small but quantifiable growth competition. A microstructural fabric study reveals that the undeformed dolomite veins show low-tortuosity vein walls and quantifiable growth competition. Here, we use a Discrete Element Method numerical modelling approach with ESyS-Particle (http://launchpad.net/esys-particle) to simulate the observed properties of the veins. Calibrated numerical specimens with a transversely isotropic matrix are repeatedly brought to failure under constant strain rates by changing the effective strain rates at model boundaries. After each fracture event, fractures in the numerical model are filled with cohesive vein material and the experiment is repeated. By systematically varying stress states, fluid pressures and mechanical properties of materials (host rock, vein infill and interface), we attempt to reproduce the characteristics of spatial distribution and thickness variation of the veins. Four parameter sets of mechanical micro-properties are defined in the models, essentially yielding (1) a competent and (2) incompetent matrix, (3) a vein material and (4) a vein-matrix interface. Each combination of parameters and particle packings is calibrated to fit a predetermined Mohr-Coulomb type failure envelope, via an automated calibration procedure. Preliminary tests already show that by varying these parameters, we are able to simulate realistically distributed cracking through crack-seal processes. Different types of veins and vein generations can be modelled, ranging from single veins, over crack-seal veins to anastomosing veins, by varying the mechanical strength of competent and incompetent matrix, vein and interface material. Further results of this approach will be presented. We will discuss our results with respect to mechanisms proposed in the literature for bedding-parallel, fibrous veins in metasedimentary rock sequences.
Lagardère, Louis; Lipparini, Filippo; Polack, Étienne; Stamm, Benjamin; Cancès, Éric; Schnieders, Michael; Ren, Pengyu; Maday, Yvon; Piquemal, Jean-Philip
2014-02-28
In this paper, we present a scalable and efficient implementation of point dipole-based polarizable force fields for molecular dynamics (MD) simulations with periodic boundary conditions (PBC). The Smooth Particle-Mesh Ewald technique is combined with two optimal iterative strategies, namely, a preconditioned conjugate gradient solver and a Jacobi solver in conjunction with the Direct Inversion in the Iterative Subspace for convergence acceleration, to solve the polarization equations. We show that both solvers exhibit very good parallel performances and overall very competitive timings in an energy-force computation needed to perform a MD step. Various tests on large systems are provided in the context of the polarizable AMOEBA force field as implemented in the newly developed Tinker-HP package which is the first implementation for a polarizable model making large scale experiments for massively parallel PBC point dipole models possible. We show that using a large number of cores offers a significant acceleration of the overall process involving the iterative methods within the context of spme and a noticeable improvement of the memory management giving access to very large systems (hundreds of thousands of atoms) as the algorithm naturally distributes the data on different cores. Coupled with advanced MD techniques, gains ranging from 2 to 3 orders of magnitude in time are now possible compared to non-optimized, sequential implementations giving new directions for polarizable molecular dynamics in periodic boundary conditions using massively parallel implementations.
Lagardère, Louis; Lipparini, Filippo; Polack, Étienne; Stamm, Benjamin; Cancès, Éric; Schnieders, Michael; Ren, Pengyu; Maday, Yvon; Piquemal, Jean-Philip
2015-01-01
In this paper, we present a scalable and efficient implementation of point dipole-based polarizable force fields for molecular dynamics (MD) simulations with periodic boundary conditions (PBC). The Smooth Particle-Mesh Ewald technique is combined with two optimal iterative strategies, namely, a preconditioned conjugate gradient solver and a Jacobi solver in conjunction with the Direct Inversion in the Iterative Subspace for convergence acceleration, to solve the polarization equations. We show that both solvers exhibit very good parallel performances and overall very competitive timings in an energy-force computation needed to perform a MD step. Various tests on large systems are provided in the context of the polarizable AMOEBA force field as implemented in the newly developed Tinker-HP package which is the first implementation for a polarizable model making large scale experiments for massively parallel PBC point dipole models possible. We show that using a large number of cores offers a significant acceleration of the overall process involving the iterative methods within the context of spme and a noticeable improvement of the memory management giving access to very large systems (hundreds of thousands of atoms) as the algorithm naturally distributes the data on different cores. Coupled with advanced MD techniques, gains ranging from 2 to 3 orders of magnitude in time are now possible compared to non-optimized, sequential implementations giving new directions for polarizable molecular dynamics in periodic boundary conditions using massively parallel implementations. PMID:26512230
NavP: Structured and Multithreaded Distributed Parallel Programming
NASA Technical Reports Server (NTRS)
Pan, Lei
2007-01-01
We present Navigational Programming (NavP) -- a distributed parallel programming methodology based on the principles of migrating computations and multithreading. The four major steps of NavP are: (1) Distribute the data using the data communication pattern in a given algorithm; (2) Insert navigational commands for the computation to migrate and follow large-sized distributed data; (3) Cut the sequential migrating thread and construct a mobile pipeline; and (4) Loop back for refinement. NavP is significantly different from the current prevailing Message Passing (MP) approach. The advantages of NavP include: (1) NavP is structured distributed programming and it does not change the code structure of an original algorithm. This is in sharp contrast to MP as MP implementations in general do not resemble the original sequential code; (2) NavP implementations are always competitive with the best MPI implementations in terms of performance. Approaches such as DSM or HPF have failed to deliver satisfying performance as of today in contrast, even if they are relatively easy to use compared to MP; (3) NavP provides incremental parallelization, which is beyond the reach of MP; and (4) NavP is a unifying approach that allows us to exploit both fine- (multithreading on shared memory) and coarse- (pipelined tasks on distributed memory) grained parallelism. This is in contrast to the currently popular hybrid use of MP+OpenMP, which is known to be complex to use. We present experimental results that demonstrate the effectiveness of NavP.
Results of the Joint DoD/OFPP Competition Workshop Held 12-13 May 1981, Washington, DC.
1981-05-01
major system level. a Competition status on programs - how do we tell how well we are doing? 3 e Mission vs. individual objectives - individuals may be...procuring a system and an economic analysis to calculate the actual savings of competition on a system (8). e The interaction of competition and multiyear...included: * The relationship of cost growth and competition , a net assessment. e The causes and costs of turbulence in Government contracts. * The
77 FR 25681 - Export Trade Certificate of Review
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-01
... Certificate of Review ACTION: Notice of Application for an Export Trade Certificate of Review SunWest Foods, Inc. SUMMARY: The Office of Competition and Economic Analysis, International Trade Administration... of Competition and Economic Analysis, International Trade Administration, (202) 482-5131 (this is not...
L-fucose utilization provides Campylobacter jejuni with a competitive advantage.
Stahl, Martin; Friis, Lorna M; Nothaft, Harald; Liu, Xin; Li, Jianjun; Szymanski, Christine M; Stintzi, Alain
2011-04-26
Campylobacter jejuni is a prevalent gastrointestinal pathogen in humans and a common commensal of poultry. When colonizing its hosts, C. jejuni comes into contact with intestinal carbohydrates, including L-fucose, released from mucin glycoproteins. Several strains of C. jejuni possess a genomic island (cj0480c-cj0490) that is up-regulated in the presence of both L-fucose and mucin and allows for the utilization of L-fucose as a substrate for growth. Strains possessing this genomic island show increased growth in the presence of L-fucose and mutation of cj0481, cj0486, and cj0487 results in the loss of the ability to grow on this substrate. Furthermore, mutants in the putative fucose permease (cj0486) are deficient in fucose uptake and demonstrate a competitive disadvantage when colonizing the piglet model of human disease, which is not paralleled in the colonization of poultry. This identifies a previously unrecorded metabolic pathway in select strains of C. jejuni associated with a virulent lifestyle.
l-Fucose utilization provides Campylobacter jejuni with a competitive advantage
Stahl, Martin; Friis, Lorna M.; Nothaft, Harald; Liu, Xin; Li, Jianjun; Szymanski, Christine M.; Stintzi, Alain
2011-01-01
Campylobacter jejuni is a prevalent gastrointestinal pathogen in humans and a common commensal of poultry. When colonizing its hosts, C. jejuni comes into contact with intestinal carbohydrates, including l-fucose, released from mucin glycoproteins. Several strains of C. jejuni possess a genomic island (cj0480c–cj0490) that is up-regulated in the presence of both l-fucose and mucin and allows for the utilization of l-fucose as a substrate for growth. Strains possessing this genomic island show increased growth in the presence of l-fucose and mutation of cj0481, cj0486, and cj0487 results in the loss of the ability to grow on this substrate. Furthermore, mutants in the putative fucose permease (cj0486) are deficient in fucose uptake and demonstrate a competitive disadvantage when colonizing the piglet model of human disease, which is not paralleled in the colonization of poultry. This identifies a previously unrecorded metabolic pathway in select strains of C. jejuni associated with a virulent lifestyle. PMID:21482772
Berglund, Fredrik; Forster, Roy P.
1958-01-01
A characterization was attempted of the mechanisms involved in the tubular transport of inorganic divalent ions by the aglomerular kidney of Lophius, attention being paid particularly to the possible existence of transport maxima (Tm) and to competition for transport among related substances undergoing tubular excretion. Excretory rates of divalent ions in non-treated fish during standard laboratory conditions paralleled spontaneous changes in urine flow. Tm rates of excretion were reached for magnesium, sulfate, and thiosulfate with corresponding plasma levels of 2 to 5, 5 to 17, and 4 to 12 µM/ml. respectively. Elevation of magnesium chloride levels in plasma markedly depressed calcium excretion; sodium thiosulfate similarly depressed sulfate excretion. Experimental observations suggest the existence of a transport system for divalent cations separate from another for divalent anions. Within each transport system the ion with the higher excretion rate depressed competitively transfer of the other ion. Neither system was influenced by probenecid (benemid) in doses which markedly depressed the simultaneous excretion rate of p-aminohippuric acid. PMID:13491814
User's Guide for ENSAERO_FE Parallel Finite Element Solver
NASA Technical Reports Server (NTRS)
Eldred, Lloyd B.; Guruswamy, Guru P.
1999-01-01
A high fidelity parallel static structural analysis capability is created and interfaced to the multidisciplinary analysis package ENSAERO-MPI of Ames Research Center. This new module replaces ENSAERO's lower fidelity simple finite element and modal modules. Full aircraft structures may be more accurately modeled using the new finite element capability. Parallel computation is performed by breaking the full structure into multiple substructures. This approach is conceptually similar to ENSAERO's multizonal fluid analysis capability. The new substructure code is used to solve the structural finite element equations for each substructure in parallel. NASTRANKOSMIC is utilized as a front end for this code. Its full library of elements can be used to create an accurate and realistic aircraft model. It is used to create the stiffness matrices for each substructure. The new parallel code then uses an iterative preconditioned conjugate gradient method to solve the global structural equations for the substructure boundary nodes.
Improved packing of protein side chains with parallel ant colonies.
Quan, Lijun; Lü, Qiang; Li, Haiou; Xia, Xiaoyan; Wu, Hongjie
2014-01-01
The accurate packing of protein side chains is important for many computational biology problems, such as ab initio protein structure prediction, homology modelling, and protein design and ligand docking applications. Many of existing solutions are modelled as a computational optimisation problem. As well as the design of search algorithms, most solutions suffer from an inaccurate energy function for judging whether a prediction is good or bad. Even if the search has found the lowest energy, there is no certainty of obtaining the protein structures with correct side chains. We present a side-chain modelling method, pacoPacker, which uses a parallel ant colony optimisation strategy based on sharing a single pheromone matrix. This parallel approach combines different sources of energy functions and generates protein side-chain conformations with the lowest energies jointly determined by the various energy functions. We further optimised the selected rotamers to construct subrotamer by rotamer minimisation, which reasonably improved the discreteness of the rotamer library. We focused on improving the accuracy of side-chain conformation prediction. For a testing set of 442 proteins, 87.19% of X1 and 77.11% of X12 angles were predicted correctly within 40° of the X-ray positions. We compared the accuracy of pacoPacker with state-of-the-art methods, such as CIS-RR and SCWRL4. We analysed the results from different perspectives, in terms of protein chain and individual residues. In this comprehensive benchmark testing, 51.5% of proteins within a length of 400 amino acids predicted by pacoPacker were superior to the results of CIS-RR and SCWRL4 simultaneously. Finally, we also showed the advantage of using the subrotamers strategy. All results confirmed that our parallel approach is competitive to state-of-the-art solutions for packing side chains. This parallel approach combines various sources of searching intelligence and energy functions to pack protein side chains. It provides a frame-work for combining different inaccuracy/usefulness objective functions by designing parallel heuristic search algorithms.
Validity and factor structure of the bodybuilding dependence scale
Smith, D; Hale, B
2004-01-01
Objectives: To investigate the factor structure, validity, and reliability of the bodybuilding dependence scale and to investigate differences in bodybuilding dependence between men and women and competitive and non-competitive bodybuilders. Methods: Seventy two male competitive bodybuilders, 63 female competitive bodybuilders, 87 male non-competitive bodybuilders, and 63 non-competitive female bodybuilders completed the bodybuilding dependence scale (BDS), the exercise dependence questionnaire (EDQ), and the muscle dysmorphia inventory (MDI). Results: Confirmatory factor analysis of the BDS supported a three factor model of bodybuilding dependence, consisting of social dependence, training dependence, and mastery dependence (Q = 3.16, CFI = 0.98, SRMR = 0.04). Internal reliability of all three subscales was high (Cronbach's α = 0.92, 0.92, and 0.93 respectively). Significant (p<0.001) and moderate correlations were found between all BDS and MDI subscales, and between five of the eight EDQ subscales. A multivariate analysis of covariance, with univariate F tests and Tukey HSD tests, revealed that both male and female competitive bodybuilders scored significantly (p<0.05) higher on all three BDS subscales than the male and female non-competitive bodybuilders. However, there were no significant sex differences on any of the BDS subscales (p>0.05). Conclusion: The three factor BDS appears to be a reliable and valid measure of bodybuilding dependence. Symptoms of bodybuilding dependence are more prevalent in competitive bodybuilders than non-competitive ones, but there are no significant sex differences in bodybuilding dependence. PMID:15039255
Nematode orphan genes are adopted by conserved regulatory networks and find a home in ecology.
Mayer, Melanie G; Sommer, Ralf J
2015-01-01
Nematode dauer formation represents an essential survival and dispersal strategy and is one of a few ecologically relevant traits that can be studied in laboratory approaches. Under harsh environmental conditions, the nematode model organisms Caenorhabditis elegans and Pristionchus pacificus arrest their development and induce the formation of stress-resistant dauer larvae in response to dauer pheromones, representing a key example of phenotypic plasticity. Previous studies have indicated that in P. pacificus, many wild isolates show cross-preference of dauer pheromones and compete for access to a limited food source. When investigating the genetic mechanisms underlying this intraspecific competition, we recently discovered that the orphan gene dauerless (dau-1) controls dauer formation by copy number variation. Our results show that dau-1 acts in parallel to or downstream of steroid hormone signaling but upstream of the nuclear hormone receptor daf-12, suggesting that DAU-1 represents a novel inhibitor of DAF-12. Phylogenetic analysis reveals that the observed copy number variation is part of a complex series of gene duplication events that occurred over short evolutionary time scales. Here, we comment on the incorporation of novel or fast-evolving genes into conserved genetic networks as a common principle for the evolution of phenotypic plasticity and intraspecific competition. We discuss the possibility that orphan genes might often function in the regulation and execution of ecologically relevant traits. Given that only few ecological processes can be studied in model organisms, the function of such genes might often go unnoticed, explaining the large number of uncharacterized genes in model system genomes.
DOE Office of Scientific and Technical Information (OSTI.GOV)
French, W.S.
1993-02-01
The exploration industry is changing, exploration technology is changing and the explorationist's job is changing. Resource companies are diversifying internationally and their central organizations are providing advisors rather than services. As a result, the relationship between the resource company and the contractor is changing. Resource companies are promoting standards so that all contract services in all parts of the world will look the same to their advisors. Contractors, for competitive reasons, want to look [open quotes]different[close quotes] from other contractors. The resource companies must encourage competition between contractors to insure the availability of new technology but must also resist themore » current trend of burdening the contractor with more and more of the risk involved in exploration. It is becoming more and more obvious that geophysical expenditures represent the best [open quotes]value added[close quotes] expenditures in exploration and development budgets. As a result, seismic-related contractors represent the growth component of our industry. The predominant growth is in 3-D seismic technology, and this growth is being further propelled by the computational power of the new generation of massively parallel computers and by recent advances in computer graphic techniques. Interpretation of seismic data involves the analysis of wavelet shapes and amplitudes prior to stacking the data. Thus, modern interpretation involves understanding compressional waves, shear waves, and propagating modes which create noise and interference. Modern interpretation and processing are carried out simultaneously, iteratively, and interactively and involve many physics-related concepts. These concepts are not merely tools for the interpretation, they are the interpretation. Explorationists who do not recognize this fact are going the way of the dinosaurs.« less
Does Competition Improve Public School Efficiency? A Spatial Analysis
ERIC Educational Resources Information Center
Misra, Kaustav; Grimes, Paul W.; Rogers, Kevin E.
2012-01-01
Advocates for educational reform frequently call for policies to increase competition between schools because it is argued that market forces naturally lead to greater efficiencies, including improved student learning, when schools face competition. Researchers examining this issue are confronted with difficulties in defining reasonable measures…
Learning Effects of an International Group Competition Project
ERIC Educational Resources Information Center
Akpinar, Murat; del Campo, Cristina; Eryarsoy, Enes
2015-01-01
This study investigates the effects of collaboration and competition on students' learning performance in a course of business statistics. The collaboration involved a simultaneously organised group competition project with analysis of real-life business problems among students. Students from the following schools participated: JAMK University of…
A Bootstrap Generalization of Modified Parallel Analysis for IRT Dimensionality Assessment
ERIC Educational Resources Information Center
Finch, Holmes; Monahan, Patrick
2008-01-01
This article introduces a bootstrap generalization to the Modified Parallel Analysis (MPA) method of test dimensionality assessment using factor analysis. This methodology, based on the use of Marginal Maximum Likelihood nonlinear factor analysis, provides for the calculation of a test statistic based on a parametric bootstrap using the MPA…
Why not private health insurance? 1. Insurance made easy
Deber, R; Gildiner, A; Baranek, P
1999-01-01
How realistic are proposals to expand the financing of Canadian health care through private insurance, either in a parallel stream or an expanded supplementary tier? Any successful business requires that revenues exceed expenditures. Under a voluntary health insurance plan those at highest risk would be the most likely to seek coverage; insurers working within a competitive market would have to limit their financial risk through such mechanisms as "risk selection" to avoid clients likely to incur high costs and/or imposing caps on the costs covered. It is unlikely that parallel private plans will have a market if a comprehensive public insurance system continues to exist and function well. Although supplementary plans are more congruous with insurance principles, they would raise costs for purchasers and would probably not provide full open-ended coverage to all potential clients. Insurance principles suggest that voluntary insurance plans that shift costs to the private sector would damage the publicly funded system and would be unable to cover costs for all services required. PMID:10497613
Parallel Online Temporal Difference Learning for Motor Control.
Caarls, Wouter; Schuitema, Erik
2016-07-01
Temporal difference (TD) learning, a key concept in reinforcement learning, is a popular method for solving simulated control problems. However, in real systems, this method is often avoided in favor of policy search methods because of its long learning time. But policy search suffers from its own drawbacks, such as the necessity of informed policy parameterization and initialization. In this paper, we show that TD learning can work effectively in real robotic systems as well, using parallel model learning and planning. Using locally weighted linear regression and trajectory sampled planning with 14 concurrent threads, we can achieve a speedup of almost two orders of magnitude over regular TD control on simulated control benchmarks. For a real-world pendulum swing-up task and a two-link manipulator movement task, we report a speedup of 20× to 60× , with a real-time learning speed of less than half a minute. The results are competitive with state-of-the-art policy search.
Serial, parallel and hierarchical decision making in primates
Zylberberg, Ariel; Lorteije, Jeannette AM; Ouellette, Brian G; De Zeeuw, Chris I; Sigman, Mariano; Roelfsema, Pieter
2017-01-01
The study of decision-making has mainly focused on isolated decisions where choices are associated with motor actions. However, problem-solving often involves considering a hierarchy of sub-decisions. In a recent study (Lorteije et al. 2015), we reported behavioral and neuronal evidence for hierarchical decision making in a task with a small decision tree. We observed a first phase of parallel evidence integration for multiple sub-decisions, followed by a phase in which the overall strategy formed. It has been suggested that a 'flat' competition between the ultimate motor actions might also explain these results. A reanalysis of the data does not support the critical predictions of flat models. We also examined the time-course of decision making in other, related tasks and report conditions where evidence integration for successive decisions is decoupled, which excludes flat models. We conclude that the flexibility of decision-making implies that the strategies are genuinely hierarchical. DOI: http://dx.doi.org/10.7554/eLife.17331.001 PMID:28648172
NASA Astrophysics Data System (ADS)
Zhang, Yingzi; Hou, Yulong; Zhang, Yanjun; Hu, Yanjun; Zhang, Liang; Gao, Xiaolong; Zhang, Huixin; Liu, Wenyi
2018-02-01
A simple and low-cost continuous liquid-level sensor based on two parallel plastic optical fibers (POFs) in a helical structure is presented. The change in the liquid level is determined by measuring the side-coupling power in the passive fiber. The side-coupling ratio is increased by just filling the gap between the two POFs with ultraviolet-curable optical cement, making the proposed sensor competitive. The experimental results show that the side-coupling power declines as the liquid level rises. The sensitivity and the measurement range are flexible and affected by the geometric parameters of the helical structure. A higher sensitivity of 0.0208 μW/mm is acquired for a smaller curvature radius of 5 mm, and the measurement range can be expanded to 120 mm by enlarging the screw pitch to 40 mm. In addition, the reversibility and temperature dependence are studied. The proposed sensor is a cost-effective solution offering the advantages of a simple fabrication process, good reversibility, and compensable temperature dependence.
Heterogeneous scalable framework for multiphase flows
DOE Office of Scientific and Technical Information (OSTI.GOV)
Morris, Karla Vanessa
2013-09-01
Two categories of challenges confront the developer of computational spray models: those related to the computation and those related to the physics. Regarding the computation, the trend towards heterogeneous, multi- and many-core platforms will require considerable re-engineering of codes written for the current supercomputing platforms. Regarding the physics, accurate methods for transferring mass, momentum and energy from the dispersed phase onto the carrier fluid grid have so far eluded modelers. Significant challenges also lie at the intersection between these two categories. To be competitive, any physics model must be expressible in a parallel algorithm that performs well on evolving computermore » platforms. This work created an application based on a software architecture where the physics and software concerns are separated in a way that adds flexibility to both. The develop spray-tracking package includes an application programming interface (API) that abstracts away the platform-dependent parallelization concerns, enabling the scientific programmer to write serial code that the API resolves into parallel processes and threads of execution. The project also developed the infrastructure required to provide similar APIs to other application. The API allow object-oriented Fortran applications direct interaction with Trilinos to support memory management of distributed objects in central processing units (CPU) and graphic processing units (GPU) nodes for applications using C++.« less
A practical approach to portability and performance problems on massively parallel supercomputers
DOE Office of Scientific and Technical Information (OSTI.GOV)
Beazley, D.M.; Lomdahl, P.S.
1994-12-08
We present an overview of the tactics we have used to achieve a high-level of performance while improving portability for a large-scale molecular dynamics code SPaSM. SPaSM was originally implemented in ANSI C with message passing for the Connection Machine 5 (CM-5). In 1993, SPaSM was selected as one of the winners in the IEEE Gordon Bell Prize competition for sustaining 50 Gflops on the 1024 node CM-5 at Los Alamos National Laboratory. Achieving this performance on the CM-5 required rewriting critical sections of code in CDPEAC assembler language. In addition, the code made extensive use of CM-5 parallel I/Omore » and the CMMD message passing library. Given this highly specialized implementation, we describe how we have ported the code to the Cray T3D and high performance workstations. In addition we will describe how it has been possible to do this using a single version of source code that runs on all three platforms without sacrificing any performance. Sound too good to be true? We hope to demonstrate that one can realize both code performance and portability without relying on the latest and greatest prepackaged tool or parallelizing compiler.« less
Falck, David; de Vlieger, Jon S B; Giera, Martin; Honing, Maarten; Irth, Hubertus; Niessen, Wilfried M A; Kool, Jeroen
2012-04-01
In this study, an integrated approach is developed for the formation, identification and biological characterization of electrochemical conversion products of p38α mitogen-activated protein kinase inhibitors. This work demonstrates the hyphenation of an electrochemical reaction cell with a continuous-flow bioaffinity assay and parallel LC-HR-MS. Competition of the formed products with a tracer (SKF-86002) that shows fluorescence enhancement in the orthosteric binding site of the p38α kinase is the readout for bioaffinity. Parallel HR-MS(n) experiments provided information on the identity of binders and non-binders. Finally, the data produced with this on-line system were compared to electrochemical conversion products generated off-line. The electrochemical conversion of 1-{6-chloro-5-[(2R,5S)-4-(4-fluorobenzyl)-2,5-dimethylpiperazine-1-carbonyl]-3aH-indol-3-yl}-2-morpholinoethane-1,2-dione resulted in eight products, three of which showed bioaffinity in the continuous-flow p38α bioaffinity assay used. Electrochemical conversion of BIRB796 resulted, amongst others, in the formation of the reactive quinoneimine structure and its corresponding hydroquinone. Both products were detected in the p38α bioaffinity assay, which indicates binding to the p38α kinase.
LSPR chip for parallel, rapid, and sensitive detection of cancer markers in serum.
Aćimović, Srdjan S; Ortega, Maria A; Sanz, Vanesa; Berthelot, Johann; Garcia-Cordero, Jose L; Renger, Jan; Maerkl, Sebastian J; Kreuzer, Mark P; Quidant, Romain
2014-05-14
Label-free biosensing based on metallic nanoparticles supporting localized surface plasmon resonances (LSPR) has recently received growing interest (Anker, J. N., et al. Nat. Mater. 2008, 7, 442-453). Besides its competitive sensitivity (Yonzon, C. R., et al. J. Am. Chem. Soc. 2004, 126, 12669-12676; Svendendahl, M., et al. Nano Lett. 2009, 9, 4428-4433) when compared to the surface plasmon resonance (SPR) approach based on extended metal films, LSPR biosensing features a high-end miniaturization potential and a significant reduction of the interrogation device bulkiness, positioning itself as a promising candidate for point-of-care diagnostic and field applications. Here, we present the first, paralleled LSPR lab-on-a-chip realization that goes well beyond the state-of-the-art, by uniting the latest advances in plasmonics, nanofabrication, microfluidics, and surface chemistry. Our system offers parallel, real-time inspection of 32 sensing sites distributed across 8 independent microfluidic channels with very high reproducibility/repeatability. This enables us to test various sensing strategies for the detection of biomolecules. In particular we demonstrate the fast detection of relevant cancer biomarkers (human alpha-feto-protein and prostate specific antigen) down to concentrations of 500 pg/mL in a complex matrix consisting of 50% human serum.
Electricity Prices in a Competitive Environment: Marginal Cost Pricing
1997-01-01
Presents the results of an analysis that focuses on two questions: (1) How are prices for competitive generation services likely to differ from regulated prices if competitive prices are based on marginal costs rather than regulated cost-of-service pricing? (2) What impacts will the competitive pricing of generation services (based on marginal costs) have on electricity consumption patterns, production costs, and the financial integrity of electricity suppliers?
1999-08-01
electrostatic repulsion between the het- eroatom and the ketone. Swain and Lupton31 have constructed a modified Hammett equation (eq 2) in which they...determined by nonlinear fit to the Michaelis-Menten equation for competitive inhibition using simple weighing. Competitive inhibition was confirmed... equation for competitive inhibition using simple weighing. Competitive inhibition was confirmed by Lineweaver - Burk analysis using simple
The role of leaf height in plant competition for sunlight: analysis of a canopy partitioning model.
Nevai, Andrew L; Vance, Richard R
2008-01-01
A global method of nullcline endpoint analysis is employed to determine the outcome of competition for sunlight between two hypothetical plant species with clonal growth form that differ solely in the height at which they place their leaves above the ground. This difference in vertical leaf placement, or canopy partitioning, produces species differences in sunlight energy capture and stem metabolic maintenance costs. The competitive interaction between these two species is analyzed by considering a special case of a canopy partitioning model (RR Vance and AL Nevai, J. Theor. Biol. 2007, 245:210-219; AL Nevai and RR Vance, J. Math. Biol. 2007, 55:105-145). Nullcline endpoint analysis is used to partition parameter space into regions within which either competitive exclusion or competitive coexistence occurs. The principal conclusion is that two clonal plant species which compete for sunlight and place their leaves at different heights above the ground but differ in no other way can, under suitable parameter values, experience stable coexistence even though they occupy an environment which varies neither over horizontal space nor through time.
The Trojan Lifetime Champions Health Survey: Development, Validity, and Reliability
Sorenson, Shawn C.; Romano, Russell; Scholefield, Robin M.; Schroeder, E. Todd; Azen, Stanley P.; Salem, George J.
2015-01-01
Context Self-report questionnaires are an important method of evaluating lifespan health, exercise, and health-related quality of life (HRQL) outcomes among elite, competitive athletes. Few instruments, however, have undergone formal characterization of their psychometric properties within this population. Objective To evaluate the validity and reliability of a novel health and exercise questionnaire, the Trojan Lifetime Champions (TLC) Health Survey. Design Descriptive laboratory study. Setting A large National Collegiate Athletic Association Division I university. Patients or Other Participants A total of 63 university alumni (age range, 24 to 84 years), including former varsity collegiate athletes and a control group of nonathletes. Intervention(s) Participants completed the TLC Health Survey twice at a mean interval of 23 days with randomization to the paper or electronic version of the instrument. Main Outcome Measure(s) Content validity, feasibility of administration, test-retest reliability, parallel-form reliability between paper and electronic forms, and estimates of systematic and typical error versus differences of clinical interest were assessed across a broad range of health, exercise, and HRQL measures. Results Correlation coefficients, including intraclass correlation coefficients (ICCs) for continuous variables and κ agreement statistics for ordinal variables, for test-retest reliability averaged 0.86, 0.90, 0.80, and 0.74 for HRQL, lifetime health, recent health, and exercise variables, respectively. Correlation coefficients, again ICCs and κ, for parallel-form reliability (ie, equivalence) between paper and electronic versions averaged 0.90, 0.85, 0.85, and 0.81 for HRQL, lifetime health, recent health, and exercise variables, respectively. Typical measurement error was less than the a priori thresholds of clinical interest, and we found minimal evidence of systematic test-retest error. We found strong evidence of content validity, convergent construct validity with the Short-Form 12 Version 2 HRQL instrument, and feasibility of administration in an elite, competitive athletic population. Conclusions These data suggest that the TLC Health Survey is a valid and reliable instrument for assessing lifetime and recent health, exercise, and HRQL, among elite competitive athletes. Generalizability of the instrument may be enhanced by additional, larger-scale studies in diverse populations. PMID:25611315
Kelly, Benjamin J; Fitch, James R; Hu, Yangqiu; Corsmeier, Donald J; Zhong, Huachun; Wetzel, Amy N; Nordquist, Russell D; Newsom, David L; White, Peter
2015-01-20
While advances in genome sequencing technology make population-scale genomics a possibility, current approaches for analysis of these data rely upon parallelization strategies that have limited scalability, complex implementation and lack reproducibility. Churchill, a balanced regional parallelization strategy, overcomes these challenges, fully automating the multiple steps required to go from raw sequencing reads to variant discovery. Through implementation of novel deterministic parallelization techniques, Churchill allows computationally efficient analysis of a high-depth whole genome sample in less than two hours. The method is highly scalable, enabling full analysis of the 1000 Genomes raw sequence dataset in a week using cloud resources. http://churchill.nchri.org/.
Olsen, Emily O’Malley; Galic, Mara; Brener, Nancy D.
2014-01-01
Introduction Most students in grades kindergarten through 12 have access to foods and beverages during the school day outside the federal school meal programs, which are called competitive foods. At the time of this study, competitive foods were subject to minimal federal nutrition standards, but states could implement additional standards. Our analysis examined the association between school nutrition practices and alignment of state policies with Institute of Medicine recommendations (IOM Standards). Methods For this analysis we used data from the Centers for Disease Control and Prevention’s (CDC’s) report, Competitive Foods and Beverages in US Schools: A State Policy Analysis and CDC’s 2010 School Health Profiles (Profiles) survey to examine descriptive associations between state policies for competitive foods and school nutrition practices. Results Access to chocolate candy, soda pop, sports drinks, and caffeinated foods or beverages was lower in schools in states with policies more closely aligned with IOM Standards. No association was found for access to fruits or nonfried vegetables. Conclusion Schools in states with policies more closely aligned with the IOM Standards reported reduced access to less healthful competitive foods. Encouraging more schools to follow these standards will help create healthier school environments and may help promote healthy eating among US children. PMID:24762530
Local cellular neighborhood controls proliferation in cell competition
Bove, Anna; Gradeci, Daniel; Fujita, Yasuyuki; Banerjee, Shiladitya; Charras, Guillaume; Lowe, Alan R.
2017-01-01
Cell competition is a quality-control mechanism through which tissues eliminate unfit cells. Cell competition can result from short-range biochemical inductions or long-range mechanical cues. However, little is known about how cell-scale interactions give rise to population shifts in tissues, due to the lack of experimental and computational tools to efficiently characterize interactions at the single-cell level. Here, we address these challenges by combining long-term automated microscopy with deep-learning image analysis to decipher how single-cell behavior determines tissue makeup during competition. Using our high-throughput analysis pipeline, we show that competitive interactions between MDCK wild-type cells and cells depleted of the polarity protein scribble are governed by differential sensitivity to local density and the cell type of each cell’s neighbors. We find that local density has a dramatic effect on the rate of division and apoptosis under competitive conditions. Strikingly, our analysis reveals that proliferation of the winner cells is up-regulated in neighborhoods mostly populated by loser cells. These data suggest that tissue-scale population shifts are strongly affected by cellular-scale tissue organization. We present a quantitative mathematical model that demonstrates the effect of neighbor cell–type dependence of apoptosis and division in determining the fitness of competing cell lines. PMID:28931601
Plastic responses of native plant root systems to the presence of an invasive annual grass.
Phillips, Allison J; Leger, Elizabeth A
2015-01-01
• The ability to respond to environmental change via phenotypic plasticity may be important for plants experiencing disturbances such as climate change and plant invasion. Responding to belowground competition through root plasticity may allow native plants to persist in highly invaded systems such as the cold deserts of the Intermountain West, USA.• We investigated whether Poa secunda, a native bunchgrass, could alter root morphology in response to nutrient availability and the presence of a competitive annual grass. Seeds from 20 families were grown with high and low nutrients and harvested after 50 d, and seeds from 48 families, grown with and without Bromus tectorum, were harvested after ∼2 or 6 mo. We measured total biomass, root mass fraction, specific root length (SRL), root tips, allocation to roots of varying diameter, and plasticity in allocation.• Plants had many parallel responses to low nutrients and competition, including increased root tip production, a trait associated with tolerance to reduced resources, though families differed in almost every trait and correlations among trait changes varied among experiments, indicating flexibility in plant responses. Seedlings actively increased SRL and fine root allocation under competition, while older seedlings also increased coarse root allocation, a trait associated with increased tolerance, and increased root mass fraction.• The high degree of genetic variation for root plasticity within natural populations could aid in the long-term persistence of P. secunda because phenotypic plasticity may allow native species to persist in invaded and fluctuating resource environments. © 2015 Botanical Society of America, Inc.
Telecommunications Policy Research Conference. Competition in the Local Loop Section. Papers.
ERIC Educational Resources Information Center
Telecommunications Policy Research Conference, Inc., Washington, DC.
Four papers consider competition, new technology and economics of local telephone companies in a deregulated environment: (1) "An Engineering and Policy Analysis of Fiber Introduction into the Residential Subscriber Loop" (Marvin Sirbu, Frank Ferrante, and David Reed); (2) "Competition in the Local Loop: Pricing Carrier Access"…
Have a Chemistry Field Day in Your Area.
ERIC Educational Resources Information Center
Mattson, Bruce M.; And Others
1989-01-01
Describes a full day of chemistry fun and competition for high school chemistry students. Notes teams have five students from each high school. Lists five competitive events for each team: titration, qualitative analysis, balancing equations, general chemistry quiz, and quantitative analysis with atomic absorption spectroscopy. (MVL)
A reliability analysis of the revised competitiveness index.
Harris, Paul B; Houston, John M
2010-06-01
This study examined the reliability of the Revised Competitiveness Index by investigating the test-retest reliability, interitem reliability, and factor structure of the measure based on a sample of 280 undergraduates (200 women, 80 men) ranging in age from 18 to 28 years (M = 20.1, SD = 2.1). The findings indicate that the Revised Competitiveness Index has high test-retest reliability, high inter-item reliability, and a stable factor structure. The results support the assertion that the Revised Competitiveness Index assesses competitiveness as a stable trait rather than a dynamic state.
Characteristic and factors of competitive maritime industry clusters in Indonesia
NASA Astrophysics Data System (ADS)
Marlyana, N.; Tontowi, A. E.; Yuniarto, H. A.
2017-12-01
Indonesia is situated in the strategic position between two oceans therefore is identified as a maritime state. The fact opens big opportunity to build a competitive maritime industry. However, potential factors to boost the competitive maritime industry still need to be explored. The objective of this paper is then to determine the main characteristics and potential factors of competitive maritime industry cluster. Qualitative analysis based on literature review has been carried out in two aspects. First, benchmarking analysis conducted to distinguish the most relevant factors of maritime clusters in several countries in Europe (Norway, Spain, South West of England) and Asia (China, South Korea, Malaysia). Seven key dimensions are used for this benchmarking. Secondly, the competitiveness of maritime clusters in Indonesia was diagnosed through a reconceptualization of Porter’s Diamond model. There were four interlinked of advanced factors in and between companies within clusters, which can be influenced in a proactive way by government.
An asymptotic induced numerical method for the convection-diffusion-reaction equation
NASA Technical Reports Server (NTRS)
Scroggs, Jeffrey S.; Sorensen, Danny C.
1988-01-01
A parallel algorithm for the efficient solution of a time dependent reaction convection diffusion equation with small parameter on the diffusion term is presented. The method is based on a domain decomposition that is dictated by singular perturbation analysis. The analysis is used to determine regions where certain reduced equations may be solved in place of the full equation. Parallelism is evident at two levels. Domain decomposition provides parallelism at the highest level, and within each domain there is ample opportunity to exploit parallelism. Run time results demonstrate the viability of the method.
Strategic Plan: Initiating an Orthopaedic Residency at Womack Army Medical Center
2006-06-07
outlining WAMC’s strategy: analysis of Porter’s Five Forces Model; a Strategic Map for discovering competitive advantages and disadvantages ; identifying a...Figure 6. Strategic Map of Advantages and Disadvantages ............................... 27 Figure 7. Directional Strategy...analysis; analysis of Porter’s Five Forces Model; a strategic map for discovering competitive advantages and disadvantages ; identifying a directional
ERIC Educational Resources Information Center
Thompson, Lawrence H.
One way in which the analysis of educational finance reform might be broadened to include an analysis of the fiscal effects of such reform is to show fiscal competition between large cities and their suburbs. It is not possible to say that "most central cities" or "most suburban areas" deserve a greater share of State…
Sleep disorder risk factors among student athletes.
Monma, Takafumi; Ando, Akira; Asanuma, Tohru; Yoshitake, Yutaka; Yoshida, Goichiro; Miyazawa, Taiki; Ebine, Naoyuki; Takeda, Satoko; Omi, Naomi; Satoh, Makoto; Tokuyama, Kumpei; Takeda, Fumi
2018-04-01
To clarify sleep disorder risk factors among student athletes, this study examined the relationship between lifestyle habits, competition activities, psychological distress, and sleep disorders. Student athletes (N = 906; male: 70.1%; average age: 19.1 ± 0.8 years) in five university sports departments from four Japanese regions were targeted for analysis. Survey items were attributes (age, gender, and body mass index), sleep disorders (recorded through the Pittsburgh Sleep Quality Index), lifestyle habits (bedtime, wake-up time, smoking, drinking alcohol, meals, part-time jobs, and use of electronics after lights out), competition activities (activity contents and competition stressors), and psychological distress (recorded through the K6 scale). The relation between lifestyle habits, competition activities, psychological distress, and sleep disorders was explored using logistic regression analysis. Results of multivariate logistic regression analysis with attributes as adjustment variables showed that "bedtime," "wake-up time," "psychological distress," "part-time jobs," "smartphone/cellphone use after lights out," "morning practices," and "motivation loss stressors," were risk factors that were independently related to sleep disorders. Sleep disorders among student athletes are related to lifestyle habits such as late bedtime, early wake-up time, late night part-time jobs, and use of smartphones/cellphones after lights out; psychological distress; and competition activities such as morning practices and motivation loss stressors related to competition. Therefore, this study suggests the importance of improving these lifestyle habits, mental health, and competition activities. Copyright © 2017 Elsevier B.V. All rights reserved.
Interference and memory capacity effects in memristive systems
NASA Astrophysics Data System (ADS)
Hermiz, John; Chang, Ting; Du, Chao; Lu, Wei
2013-02-01
Short-term memory implies the existence of a capacity limit beyond which memory cannot be securely formed and retained. The underlying mechanisms are believed to be two primary factors: decay and interference. Here, we demonstrate through both simulation and experiment that the memory capacity effect can be implemented in a parallel memristor circuit, where decay and interference are achieved by the inherent ion diffusion in the device and the competition for current supply in the circuit, respectively. This study suggests it is possible to emulate high-level biological behaviors with memristor circuits and will stimulate continued studies on memristor-based neuromorphic circuits.
Insolvency risk in health carriers: innovation, competition, and public protection.
Akula, J L
1997-01-01
This paper reviews the framework of regulatory and managerial devices that have evolved in response to the special dangers to the public posed by insolvency of health carriers. These devices include "prudential" measures designed to decrease the likelihood of insolvency, and measures to "protect enrollees" in the event that insolvency occurs nevertheless. It also reviews the current debate over how this framework should be adapted to new forms of risk-bearing entities, especially provider-sponsored networks engaged in direct contracting with purchasers of coverage. Parallels to solvency concerns in the banking industry are explored.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-18
... technical analysis submitted for parallel-processing by DNREC on December 9, 2010, to address significant... technical analysis submitted by DNREC for parallel-processing on December 9, 2010, to satisfy the... consists of a technical analysis that provides detailed support for Delaware's position that it has...
National Combustion Code: Parallel Implementation and Performance
NASA Technical Reports Server (NTRS)
Quealy, A.; Ryder, R.; Norris, A.; Liu, N.-S.
2000-01-01
The National Combustion Code (NCC) is being developed by an industry-government team for the design and analysis of combustion systems. CORSAIR-CCD is the current baseline reacting flow solver for NCC. This is a parallel, unstructured grid code which uses a distributed memory, message passing model for its parallel implementation. The focus of the present effort has been to improve the performance of the NCC flow solver to meet combustor designer requirements for model accuracy and analysis turnaround time. Improving the performance of this code contributes significantly to the overall reduction in time and cost of the combustor design cycle. This paper describes the parallel implementation of the NCC flow solver and summarizes its current parallel performance on an SGI Origin 2000. Earlier parallel performance results on an IBM SP-2 are also included. The performance improvements which have enabled a turnaround of less than 15 hours for a 1.3 million element fully reacting combustion simulation are described.
Decoupling Principle Analysis and Development of a Parallel Three-Dimensional Force Sensor
Zhao, Yanzhi; Jiao, Leihao; Weng, Dacheng; Zhang, Dan; Zheng, Rencheng
2016-01-01
In the development of the multi-dimensional force sensor, dimension coupling is the ubiquitous factor restricting the improvement of the measurement accuracy. To effectively reduce the influence of dimension coupling on the parallel multi-dimensional force sensor, a novel parallel three-dimensional force sensor is proposed using a mechanical decoupling principle, and the influence of the friction on dimension coupling is effectively reduced by making the friction rolling instead of sliding friction. In this paper, the mathematical model is established by combining with the structure model of the parallel three-dimensional force sensor, and the modeling and analysis of mechanical decoupling are carried out. The coupling degree (ε) of the designed sensor is defined and calculated, and the calculation results show that the mechanical decoupling parallel structure of the sensor possesses good decoupling performance. A prototype of the parallel three-dimensional force sensor was developed, and FEM analysis was carried out. The load calibration and data acquisition experiment system are built, and then calibration experiments were done. According to the calibration experiments, the measurement accuracy is less than 2.86% and the coupling accuracy is less than 3.02%. The experimental results show that the sensor system possesses high measuring accuracy, which provides a basis for the applied research of the parallel multi-dimensional force sensor. PMID:27649194
Price Analysis and the Effects of Competition.
1985-10-01
state of the market . For instance, is it possible that competition can squeeze a company to greater efficiency or lower profits in the short run, but...dual- source competition . The Stackelberg model recognizes two types of firm behavior. A firm may choose to be a leader and pursue a dominant market ...strate- gies in areas of potential competition . In this instance, the follower firm will serve that segment of the market that the leader firm cannot
Competitive Advantage, Uncertainty, and Weapons Procurement: Striking Balance for the Future
2009-05-02
position of the Department of the Army, Department of Defense, or the U.S. Government. COMPETITIVE ADVANTAGE , UNCERTAINTY, AND WEAPONS PROCUREMENT: STRIKING...Competitive Advantage , Uncertainty, and Weapons Procurement: Striking Balance for the Future 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d...the right balance of investments all leading to a sustained competitive advantage . This paper presents an analysis of how effective this overhaul has
Interpretation Analysis as a Competitive Event.
ERIC Educational Resources Information Center
Nading, Robert M.
Interpretation analysis is a new and interesting event on the forensics horizon which appears to be attracting an ever larger number of supporters. This event, developed by Larry Lambert of Ball State University in 1989, requires a student to perform all three disciplines of forensic competition (interpretation, public speaking, and limited…
43 CFR 3420.3-4 - Regional tract ranking, selection, environmental analysis and scheduling.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Regional tract ranking, selection...) COMPETITIVE LEASING Competitive Leasing § 3420.3-4 Regional tract ranking, selection, environmental analysis... natural environment; and socioeconomic impacts. The subfactors the regional coal team will consider under...
Parallel processing of genomics data
NASA Astrophysics Data System (ADS)
Agapito, Giuseppe; Guzzi, Pietro Hiram; Cannataro, Mario
2016-10-01
The availability of high-throughput experimental platforms for the analysis of biological samples, such as mass spectrometry, microarrays and Next Generation Sequencing, have made possible to analyze a whole genome in a single experiment. Such platforms produce an enormous volume of data per single experiment, thus the analysis of this enormous flow of data poses several challenges in term of data storage, preprocessing, and analysis. To face those issues, efficient, possibly parallel, bioinformatics software needs to be used to preprocess and analyze data, for instance to highlight genetic variation associated with complex diseases. In this paper we present a parallel algorithm for the parallel preprocessing and statistical analysis of genomics data, able to face high dimension of data and resulting in good response time. The proposed system is able to find statistically significant biological markers able to discriminate classes of patients that respond to drugs in different ways. Experiments performed on real and synthetic genomic datasets show good speed-up and scalability.
Revisiting the Al/Al₂O₃ interface: coherent interfaces and misfit accommodation.
Pilania, Ghanshyam; Thijsse, Barend J; Hoagland, Richard G; Lazić, Ivan; Valone, Steven M; Liu, Xiang-Yang
2014-03-27
We study the coherent and semi-coherent Al/α-Al2O3 interfaces using molecular dynamics simulations with a mixed, metallic-ionic atomistic model. For the coherent interfaces, both Al-terminated and O-terminated nonstoichiometric interfaces have been studied and their relative stability has been established. To understand the misfit accommodation at the semi-coherent interface, a 1-dimensional (1D) misfit dislocation model and a 2-dimensional (2D) dislocation network model have been studied. For the latter case, our analysis reveals an interface dislocation structure with a network of three sets of parallel dislocations, each with pure-edge character, giving rise to a pattern of coherent and stacking-fault-like regions at the interface. Structural relaxation at elevated temperatures leads to a further change of the dislocation pattern, which can be understood in terms of a competition between the stacking fault energy and the dislocation interaction energy at the interface. Our results are expected to serve as an input for the subsequent dislocation dynamics models to understand and predict the macroscopic mechanical behavior of Al/α-Al2O3 composite heterostructures.
Magnetically-induced ferroelectricity in the (ND4)2[FeCl5(D2O)] molecular compound
Alberto Rodríguez-Velamazán, José; Fabelo, Óscar; Millán, Ángel; Campo, Javier; Johnson, Roger D.; Chapon, Laurent
2015-01-01
The number of magnetoelectric multiferroic materials reported to date is scarce, as magnetic structures that break inversion symmetry and induce an improper ferroelectric polarization typically arise through subtle competition between different magnetic interactions. The (NH4)2[FeCl5(H2O)] compound is a rare case where such improper ferroelectricity has been observed in a molecular material. We have used single crystal and powder neutron diffraction to obtain detailed solutions for the crystal and magnetic structures of (NH4)2[FeCl5(H2O)], from which we determined the mechanism of multiferroicity. From the crystal structure analysis, we observed an order-disorder phase transition related to the ordering of the ammonium counterion. We have determined the magnetic structure below TN, at 2 K and zero magnetic field, which corresponds to a cycloidal spin arrangement with magnetic moments contained in the ac-plane, propagating parallel to the c-axis. The observed ferroelectricity can be explained, from the obtained magnetic structure, via the inverse Dzyaloshinskii-Moriya mechanism. PMID:26417890
High Performance, Low Cost Hydrogen Generation from Renewable Energy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ayers, Katherine; Dalton, Luke; Roemer, Andy
Renewable hydrogen from proton exchange membrane (PEM) electrolysis is gaining strong interest in Europe, especially in Germany where wind penetration is already at critical levels for grid stability. For this application as well as biogas conversion and vehicle fueling, megawatt (MW) scale electrolysis is required. Proton has established a technology roadmap to achieve the necessary cost reductions and manufacturing scale up to maintain U.S. competitiveness in these markets. This project represents a highly successful example of the potential for cost reduction in PEM electrolysis, and provides the initial stack design and manufacturing development for Proton’s MW scale product launch. Themore » majority of the program focused on the bipolar assembly, from electrochemical modeling to subscale stack development through prototyping and manufacturing qualification for a large active area cell platform. Feasibility for an advanced membrane electrode assembly (MEA) with 50% reduction in catalyst loading was also demonstrated. Based on the progress in this program and other parallel efforts, H2A analysis shows the status of PEM electrolysis technology dropping below $3.50/kg production costs, exceeding the 2015 target.« less
NASA Astrophysics Data System (ADS)
Dowell, M.; Moore, T.; Follows, M.; Dutkiewicz, S.
2006-12-01
In recent years there has been significant progress both in the use of satellite ocean colour remote sensing and coupled hydrodynamic biological models for producing maps of different dominant phytoplankton groups in the global ocean. In parallel to these initiatives, there is ongoing research largely following on from Alan Longhurst's seminal work on defining a template of distinct ecological and biogeochemical provinces for the oceans based on their physical and biochemical characteristics. For these products and models to be of maximum use in their subsequent inclusion in re-analysis and climate scale models, there is a need to understand how the "observed" distributions of dominant phytoplankton (realized niche) coincide with of the environmental constraints in which they occur (fundamental niche). In the current paper, we base our analysis on the recently published results on the distribution of dominant phytoplankton species at global scale, resulting both from satellite and model analysis. Furthermore, we will present research in defining biogeochemical provinces using satellite and model data inputs and a fuzzy logic based approach. This will be compared with ongoing modelling efforts, which include competitive exclusion and therefore compatible with the definition of the realized ecological niche, to define the emergent distribution of dominant phytoplankton species. Ultimately we investigate the coherence of these two distinct approaches in studying phytoplankton distributions and propose the significance of this in the context of modelling and analysis at various scales.
Scaling deep learning workloads: NVIDIA DGX-1/Pascal and Intel Knights Landing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gawande, Nitin A.; Landwehr, Joshua B.; Daily, Jeffrey A.
Deep Learning (DL) algorithms have become ubiquitous in data analytics. As a result, major computing vendors --- including NVIDIA, Intel, AMD, and IBM --- have architectural road-maps influenced by DL workloads. Furthermore, several vendors have recently advertised new computing products as accelerating large DL workloads. Unfortunately, it is difficult for data scientists to quantify the potential of these different products. This paper provides a performance and power analysis of important DL workloads on two major parallel architectures: NVIDIA DGX-1 (eight Pascal P100 GPUs interconnected with NVLink) and Intel Knights Landing (KNL) CPUs interconnected with Intel Omni-Path or Cray Aries. Ourmore » evaluation consists of a cross section of convolutional neural net workloads: CifarNet, AlexNet, GoogLeNet, and ResNet50 topologies using the Cifar10 and ImageNet datasets. The workloads are vendor-optimized for each architecture. Our analysis indicates that although GPUs provide the highest overall performance, the gap can close for some convolutional networks; and the KNL can be competitive in performance/watt. We find that NVLink facilitates scaling efficiency on GPUs. However, its importance is heavily dependent on neural network architecture. Furthermore, for weak-scaling --- sometimes encouraged by restricted GPU memory --- NVLink is less important.« less
Optoelectronics-related competence building in Japanese and Western firms
NASA Astrophysics Data System (ADS)
Miyazaki, Kumiko
1992-05-01
In this paper, an analysis is made of how different firms in Japan and the West have developed competence related to optoelectronics on the basis of their previous experience and corporate strategies. The sample consists of a set of seven Japanese and four Western firms in the industrial, consumer electronics and materials sectors. Optoelectronics is divided into subfields including optical communications systems, optical fibers, optoelectronic key components, liquid crystal displays, optical disks, and others. The relative strengths and weaknesses of companies in the various subfields are determined using the INSPEC database, from 1976 to 1989. Parallel data are analyzed using OTAF U.S. patent statistics and the two sets of data are compared. The statistical analysis from the database is summarized for firms in each subfield in the form of an intra-firm technology index (IFTI), a new technique introduced to assess the revealed technology advantage of firms. The quantitative evaluation is complemented by results from intensive interviews with the management and scientists of the firms involved. The findings show that there is a marked variation in the way firms' technological trajectories have evolved giving rise to strength in some and weakness in other subfields for the different companies, which are related to their accumulated core competencies, previous core business activities, organizational, marketing, and competitive factors.
ERIC Educational Resources Information Center
Onsomu, Eldah N.; Ngware, Moses W.; Manda, Damiano K.
2010-01-01
In the past half-century, most countries have emphasized the development of human capital as an instrument for economic growth, sustainable development, and improved global competitiveness. However, limited evidence exists on the link between skills development and a country's competitiveness. This paper examines the contribution and association…
A Proposal for Facilitating More Cooperation in Competitive Sports
ERIC Educational Resources Information Center
Jacobs, George M.; Teh, Jiexin; Spencer, Leonora
2017-01-01
This article utilises theories, methods and tools from the fields of Social Psychology and Education to suggest new metrics for the analysis of competitive sport. The hope is that these metrics will encourage cooperation to exist alongside of the dominant feelings of competition. The main theory from Social Psychology involved here is Social…
Competition and Markets in Higher Education: A "Glonacal" Analysis
ERIC Educational Resources Information Center
Marginson, Simon
2004-01-01
Higher education--particularly the research-intensive university, which is the focus of this article--is the subject of global/national/local effects, and is shaped by hierarchy and uneven development on a world scale. The article theorises social competition in higher education, and traces inter-university competition and stratification on the…
ERIC Educational Resources Information Center
Vannoy, Sandra A.
2010-01-01
This dissertation examines, from a managerial interpretive perspective, how information systems contribute to firms' specific competitive actions and responses, and the resultant impacts upon firm performance. The findings from this research suggest that the answer may well lie within the role of information systems in firms' competitive dynamics…
Rules? Relationships?: A Feminist Analysis of Competition and Fair Play in Physical Education
ERIC Educational Resources Information Center
Singleton, Ellen
2003-01-01
Regardless of recent curriculum revisions, physical educators, faced with reduced time and/or inadequate equipment and facilities, continue to offer competitive team sport activities for a high percentage of their program time. When competition is only experienced as a win-lose situation, possibilities that students will derive any morally…
How Are Investment Returns Affected By Competition Control and Southern Oak Seedling Survival?
Donald L. Grebner; Andrew W. Ezell; Deborah A. Gaddis; Steven H. Bullard
2004-01-01
Increasing numbers of landowners are establishing hardwood plantations to satisfy their management objectives. Despite a dearth of research on competition control and its effects on initial hardwood plantation survival and investment returns, this study examines alternative competition control regimes for southern oak establishment. The analysis includes estimates of...
Marketing Schools: Consumer Goods and Competitive Incentives for Consumer Information
ERIC Educational Resources Information Center
Lubienski, Christopher
2007-01-01
Effective school-choice plans depend on the quality of information available to families. Examining the promotional materials provided by different schools in a highly competitive and diverse urban area tells us not only about the quality of that information but also how schools respond to competitive incentives. This analysis outlines an economic…
Orosz, Gábor; Tóth-Király, István; Büki, Noémi; Ivaskevics, Krisztián; Bőthe, Beáta; Fülöp, Márta
2018-01-01
To date, no short scale exists with established factor structure that can assess individual differences in competition. The aim of the present study was to uncover and operationalize the facets of competitive orientations with theoretical underpinning and strong psychometric properties. A total of 2676 respondents were recruited for four studies. The items were constructed based on qualitative research in different cultural contexts. A combined method of exploratory structural equation modeling (ESEM) and confirmatory factor analysis (CFA) was employed. ESEM resulted in a four-factor structure of the competitive orientations and this structure was supported by a series of CFAs on different comprehensive samples. The Multidimensional Competitive Orientation Inventory (MCOI) included 12 items and four factors: hypercompetitive orientation, self-developmental competitive orientation, anxiety-driven competition avoidance, and lack of interest toward competition. Strong gender invariance was established. The four facets of competition have differentiated relationship patterns with adaptive and maladaptive personality and motivational constructs. The MCOI can assess the adaptive and maladaptive facets of competitive orientations with a short, reliable, valid and theoretically underlined multidimensional measure. PMID:29872415
The use of heart rate variability in assessing precompetitive stress in high-standard judo athletes.
Morales, J; Garcia, V; García-Massó, X; Salvá, P; Escobar, R; Buscà, B
2013-02-01
The objective of this study is to examine the sensitivity to and changes in heart rate variability (HRV) in stressful situations before judo competitions and to observe the differences among judo athletes according to their competitive standards in both official and unofficial competitions. 24 (10 male and 14 female) national- and international-standard athletes were evaluated. Each participant answered the Revised Competitive State Anxiety Inventory (CSAI-2R) and their HRV was recorded both during an official and unofficial competition. The MANOVA showed significant main effects of the athlete's standard and the type of competition in CSAI-2R, in HRV time domain, in HRV frequency domain and in HRV nonlinear analysis (p<0.05). International-standard judo athletes have lower somatic anxiety, cognitive anxiety, heart rate and low-high frequency ratio than national-standard athletes (p<0.05). International-standard athletes have a higher confidence, mean RR interval, standard deviation of RR, square root of the mean squared difference of successive RR intervals, number of consecutive RR that differ by more than 5 ms, short-term variability, long-term variability, long-range scaling exponents and short-range scaling exponent than national-standard judo athletes. In conclusion, international-standard athletes show less pre-competitive anxiety than the national-standard athletes and HRV analysis is sensitive to changes in pre-competitive anxiety. © Georg Thieme Verlag KG Stuttgart · New York.
Cost-benefit analysis: the first real rule of fight club?
Hillman, Kristin L.
2013-01-01
Competition is ubiquitous among social animals. Vying against a conspecific to achieve a particular outcome often requires one to act aggressively, but this is a costly and inherently risky behavior. So why do we aggressively compete, or at the extreme, fight against others? Early work suggested that competitive aggression might stem from an innate aggressive tendency, emanating from subcortical structures. Later work highlighted key cortical regions that contribute toward an instrumental aggression network, one that is recruited or suppressed as needed to achieve a goal. Recent neuroimaging work hints that competitive aggression is upmost a cost-benefit decision, in that it appears to recruit many components of traditional, non-social decision-making networks. This review provides a historical glimpse into the neuroscience of competitive aggression, and proposes a conceptual advancement for studying competitive behavior by outlining how utility calculations of contested-for resources are skewed, pre- and post-competition. A basic multi-factorial model of utility assessment is proposed to account for competitive endowment effects that stem from the presence of peers, peer salience and disposition, and the tactical effort required for victory. In part, competitive aggression is a learned behavior that should only be repeated if positive outcomes are achieved. However, due to skewed utility assessments, deviations of associative learning occur. Hence truly careful cost-benefit analysis is warranted before choosing to vie against another. PMID:24391531
Cost-benefit analysis: the first real rule of fight club?
Hillman, Kristin L
2013-12-19
Competition is ubiquitous among social animals. Vying against a conspecific to achieve a particular outcome often requires one to act aggressively, but this is a costly and inherently risky behavior. So why do we aggressively compete, or at the extreme, fight against others? Early work suggested that competitive aggression might stem from an innate aggressive tendency, emanating from subcortical structures. Later work highlighted key cortical regions that contribute toward an instrumental aggression network, one that is recruited or suppressed as needed to achieve a goal. Recent neuroimaging work hints that competitive aggression is upmost a cost-benefit decision, in that it appears to recruit many components of traditional, non-social decision-making networks. This review provides a historical glimpse into the neuroscience of competitive aggression, and proposes a conceptual advancement for studying competitive behavior by outlining how utility calculations of contested-for resources are skewed, pre- and post-competition. A basic multi-factorial model of utility assessment is proposed to account for competitive endowment effects that stem from the presence of peers, peer salience and disposition, and the tactical effort required for victory. In part, competitive aggression is a learned behavior that should only be repeated if positive outcomes are achieved. However, due to skewed utility assessments, deviations of associative learning occur. Hence truly careful cost-benefit analysis is warranted before choosing to vie against another.
Cravana, Cristina; Medica, P; Ragonese, G; Fazio, E
2017-01-01
To investigate the effects of training sessions on circulating β-endorphin changes in sport horses before and after competition and to ascertain whether competition would affect this response. A total of 24 trained jumping horses were randomly assigned to one of two training groups: Group A (competing) and Group B (not competing). To determined plasma β-endorphin concentrations, two pre- and post-competition training weeks at aerobic workout and two competitive show jumping event days at anaerobic workout were measured before, 5 and 30 min after exercise. Exercise intensity is described using lactate concentrations and heart rate. The circuit design, intensity, and duration of training sessions were the same for both groups. In Group A, one-way analysis of variance for repeated measures (RM-ANOVA) showed significant effects of exercise on β-endorphin changes (F=14.41; p<0.001), only in the post-competition training sessions, while in Group B showed no significant effects. Two-way RM-ANOVA showed, after post-competition training sessions, a significant difference between Group A and Group B (F=6.235; p=0.023), with higher β-endorphin changes in Group A, compared to Group B. During the competitive show jumping sessions, one-way RM ANOVA showed significant effects of exercise on β-endorphin changes (F=51.10; p<0.001). The statistical analysis, in Group A, showed a significant difference between post-competition training and competitive exercise (F=6.32; p=0.024) with higher β-endorphin values in competitive sessions compared to those of post-competition training. Lactate concentrations seem to be the main factors being correlated with the raise of β-endorphin during anaerobic exercise of competitive events. Exercise of low intensity, as well as that one of training sessions, does not appear to stimulate a significant increased release of β-endorphin and it may depend on the duration of the exercise program. Moreover, the responses during exercise in the course of post-competition training sessions seem to be significantly different from those the pre-competition training. These data show that the preliminary competitive stress induced additional significant changes of β-endorphin pattern. It would reflect the need of a long-lasting modulation of fatigue and pain perception related to the effect of an additional physical and mental effort for the consecutive competitive and training sessions.
Accuracy of the Parallel Analysis Procedure with Polychoric Correlations
ERIC Educational Resources Information Center
Cho, Sun-Joo; Li, Feiming; Bandalos, Deborah
2009-01-01
The purpose of this study was to investigate the application of the parallel analysis (PA) method for choosing the number of factors in component analysis for situations in which data are dichotomous or ordinal. Although polychoric correlations are sometimes used as input for component analyses, the random data matrices generated for use in PA…
NASA Astrophysics Data System (ADS)
Shelomentsev, A. G.; Medvedev, M. A.; Isaichik, K. F.; Dyomina, M. I.; Berg, I. A.; Kit, M.
2017-12-01
This paper discusses comparative analysis of trajectories in the development of participating countries of the Eurasian Economic Union (EAEC) in a two-dimensional phase space. The coordinates in the space is represented by the value of a dynamic variable that is a key indicator of the country's development, and the rate of its relative growth. This allows for construction of a ternary classification diagram describing competitive behavior strategies of countries in question. The comparative analysis was run for two primary factors: the size of investment in the main capital and R&D spendings. The authors carried out analysis and identification of competitive strategies for the behavior of the EAEC countries, as well as he proposed conclusions and recommendations on improving the policy of economic development.
Kindlmann, Gordon; Chiw, Charisee; Seltzer, Nicholas; Samuels, Lamont; Reppy, John
2016-01-01
Many algorithms for scientific visualization and image analysis are rooted in the world of continuous scalar, vector, and tensor fields, but are programmed in low-level languages and libraries that obscure their mathematical foundations. Diderot is a parallel domain-specific language that is designed to bridge this semantic gap by providing the programmer with a high-level, mathematical programming notation that allows direct expression of mathematical concepts in code. Furthermore, Diderot provides parallel performance that takes advantage of modern multicore processors and GPUs. The high-level notation allows a concise and natural expression of the algorithms and the parallelism allows efficient execution on real-world datasets.
NASA Technical Reports Server (NTRS)
Smith, Garrett; Phillips, Alan
2002-01-01
There are currently three dominant TSTO class architectures. These are Series Burn (SB), Parallel Burn with crossfeed (PBw/cf), and Parallel Burn without crossfeed (PBncf). The goal of this study was to determine what factors uniquely affect PBncf architectures, how each of these factors interact, and to determine from a performance perspective whether a PBncf vehicle could be competitive with a PBw/cf or SB vehicle using equivalent technology and assumptions. In all cases, performance was evaluated on a relative basis for a fixed payload and mission by comparing gross and dry vehicle masses of a closed vehicle. Propellant combinations studied were LOX: LH2 propelled orbiter and booster (HH) and LOX: Kerosene booster with LOX: LH2 orbiter (KH). The study conclusions were: 1) a PBncf orbiter should be throttled as deeply as possible after launch until the staging point. 2) a detailed structural model is essential to accurate architecture analysis and evaluation. 3) a PBncf TSTO architecture is feasible for systems that stage at mach 7. 3a) HH architectures can achieve a mass growth relative to PBw/cf of < 20%. 3b) KH architectures can achieve a mass growth relative to Series Burn of < 20%. 4) center of gravity (CG) control will be a major issue for a PBncf vehicle, due to the low orbiter specific thrust to weight ratio and to the position of the orbiter required to align the nozzle heights at liftoff. 5 ) thrust to weight ratios of 1.3 at liftoff and between 1.0 and 0.9 when staging at mach 7 appear to be close to ideal for PBncf vehicles. 6) performance for all vehicles studied is better when staged at mach 7 instead of mach 5. The study showed that a Series Burn architecture has the lowest gross mass for HH cases, and has the lowest dry mass for KH cases. The potential disadvantages of SB are the required use of an air-start for the orbiter engines and potential CG control issues. A Parallel Burn with crossfeed architecture solves both these problems, but the mechanics of a large bipropellant crossfeed system pose significant technical difficulties. Parallel Burn without crossfeed vehicles start both booster and orbiter engines on the ground and thus avoid both the risk of orbiter air-start and the complexity of a crossfeed system. The drawback is that the orbiter must use 20% to 35% of its propellant before reaching the staging point. This induces a weight penalty in the orbiter in order to carry additional propellant, which causes a further weight penalty in the booster to achieve the same staging point. One way to reduce the orbiter propellant consumption during the first stage is to throttle down the orbiter engines as much as possible. Another possibility is to use smaller or fewer engines. Throttling the orbiter engines soon after liftoff minimizes CG control problems due to a low orbiter liftoff thrust, but may result in an unnecessarily high orbiter thrust after staging. Reducing the number or size of engines size may cause CG control problems and drift at launch. The study suggested possible methods to maximize performance of PBncf vehicle architectures in order to meet mission design requirements.
Interfacing Computer Aided Parallelization and Performance Analysis
NASA Technical Reports Server (NTRS)
Jost, Gabriele; Jin, Haoqiang; Labarta, Jesus; Gimenez, Judit; Biegel, Bryan A. (Technical Monitor)
2003-01-01
When porting sequential applications to parallel computer architectures, the program developer will typically go through several cycles of source code optimization and performance analysis. We have started a project to develop an environment where the user can jointly navigate through program structure and performance data information in order to make efficient optimization decisions. In a prototype implementation we have interfaced the CAPO computer aided parallelization tool with the Paraver performance analysis tool. We describe both tools and their interface and give an example for how the interface helps within the program development cycle of a benchmark code.
NASA Astrophysics Data System (ADS)
Li, Xing; Yang, Zihan; Zhang, Peiyao
2017-03-01
In recent years, there has been an increasing concern over the topics of enterprise green management and environmental performance’s influence on a company’s competitive edge. This paper mainly analyzed the effect of enterprise green management on a company’s environmental performance and its competitive advantages, as well as environmental performance’s influence over the competitive edge. Furthermore, this paper discussed the role of environmental performance between enterprise green management and competitive edge. Objects of this study are manufactures in northwestern China which have acquired the ISO 9001 certification before December, 2014. Research discoveries shows that enterprise green management would exert positive influence on the environmental performance and its competitive edge; the environmental performance could also add significant competitive edge to a company; last but not the least, environmental performance also plays an intermediary role between enterprise green management and its competitive advantages
Niu, Shuli; Liu, Weixing; Wan, Shiqiang
2008-01-01
Understanding temporal niche separation between C(3) and C(4) species (e.g. C(3) species flourishing in a cool spring and autumn while C(4) species being more active in a hot summer) is essential for exploring the mechanism for their co-existence. Two parallel pot experiments were conducted, with one focusing on water and the other on nitrogen (N), to examine growth responses to water or nitrogen (N) seasonality and competition of two co-existing species Leymus chinensis (C(3) grass) and Chloris virgata (C(4) grass) in a grassland. The two species were planted in either monoculture (two individuals of one species per pot) or a mixture (two individuals including one L. chinensis and one C. virgata per pot) under three different water or N seasonality regimes, i.e. the average model (AM) with water or N evenly distributed over the growing season, the one-peak model (OPM) with more water or N in the summer than in the spring and autumn, and the two-peak model (TPM) with more water or N in the spring and autumn than in the summer. Seasonal water regimes significantly affected biomass in L. chinensis but not in C. virgata, while N seasonality impacted biomass and relative growth rate of both species over the growing season. L. chinensis accumulated more biomass under the AM and TPM than OPM water or N treatments. Final biomass of C. virgata was less impacted by water and N seasonality than that of L. chinensis. Interspecific competition significantly decreased final biomass in L. chinensis but not in C. virgata, suggesting an asymmetric competition between the two species. The magnitude of interspecific competition varied with water and N seasonality. Changes in productivity and competition balance of L. chinensis and C. virgata under shifting seasonal water and N availabilities suggest a contribution of seasonal variability in precipitation and N to the temporal niche separation between C(3) and C(4) species.
StrAuto: automation and parallelization of STRUCTURE analysis.
Chhatre, Vikram E; Emerson, Kevin J
2017-03-24
Population structure inference using the software STRUCTURE has become an integral part of population genetic studies covering a broad spectrum of taxa including humans. The ever-expanding size of genetic data sets poses computational challenges for this analysis. Although at least one tool currently implements parallel computing to reduce computational overload of this analysis, it does not fully automate the use of replicate STRUCTURE analysis runs required for downstream inference of optimal K. There is pressing need for a tool that can deploy population structure analysis on high performance computing clusters. We present an updated version of the popular Python program StrAuto, to streamline population structure analysis using parallel computing. StrAuto implements a pipeline that combines STRUCTURE analysis with the Evanno Δ K analysis and visualization of results using STRUCTURE HARVESTER. Using benchmarking tests, we demonstrate that StrAuto significantly reduces the computational time needed to perform iterative STRUCTURE analysis by distributing runs over two or more processors. StrAuto is the first tool to integrate STRUCTURE analysis with post-processing using a pipeline approach in addition to implementing parallel computation - a set up ideal for deployment on computing clusters. StrAuto is distributed under the GNU GPL (General Public License) and available to download from http://strauto.popgen.org .
Parallelizing Timed Petri Net simulations
NASA Technical Reports Server (NTRS)
Nicol, David M.
1993-01-01
The possibility of using parallel processing to accelerate the simulation of Timed Petri Nets (TPN's) was studied. It was recognized that complex system development tools often transform system descriptions into TPN's or TPN-like models, which are then simulated to obtain information about system behavior. Viewed this way, it was important that the parallelization of TPN's be as automatic as possible, to admit the possibility of the parallelization being embedded in the system design tool. Later years of the grant were devoted to examining the problem of joint performance and reliability analysis, to explore whether both types of analysis could be accomplished within a single framework. In this final report, the results of our studies are summarized. We believe that the problem of parallelizing TPN's automatically for MIMD architectures has been almost completely solved for a large and important class of problems. Our initial investigations into joint performance/reliability analysis are two-fold; it was shown that Monte Carlo simulation, with importance sampling, offers promise of joint analysis in the context of a single tool, and methods for the parallel simulation of general Continuous Time Markov Chains, a model framework within which joint performance/reliability models can be cast, were developed. However, very much more work is needed to determine the scope and generality of these approaches. The results obtained in our two studies, future directions for this type of work, and a list of publications are included.
Analysis of competition performance in dressage and show jumping of Dutch Warmblood horses.
Rovere, G; Ducro, B J; van Arendonk, J A M; Norberg, E; Madsen, P
2016-12-01
Most Warmblood horse studbooks aim to improve the performance in dressage and show jumping. The Dutch Royal Warmblood Studbook (KWPN) includes the highest score achieved in competition by a horse to evaluate its genetic ability of performance. However, the records collected during competition are associated with some aspects that might affect the quality of the genetic evaluation based on these records. These aspects include the influence of rider, censoring and preselection of the data. The aim of this study was to quantify the impact of rider effect, censoring and preselection on the genetic analysis of competition data of dressage and show jumping of KWPN. Different models including rider effect were evaluated. To assess the impact of censoring, genetic parameters were estimated in data sets that differed in the degree of censoring. The effect of preselection on variance components was analysed by defining a binary trait (sport-status) depending on whether the horse has a competition record or not. This trait was included in a bivariate model with the competition trait and used all horses registered by KWPN since 1984. Results showed that performance in competition for dressage and show jumping is a heritable trait (h 2 ~ 0.11-0.13) and that it is important to account for the effect of rider in the genetic analysis. Censoring had a small effect on the genetic parameter for highest performance achieved by the horse. A moderate heritability obtained for sport-status indicates that preselection has a genetic basis, but the effect on genetic parameters was relatively small. © 2016 Blackwell Verlag GmbH.
Coyne, Joseph O C; Tran, Tai T; Secomb, Josh L; Lundgren, Lina E; Farley, Oliver R L; Newton, Robert U; Sheppard, Jeremy M
2017-01-01
Coyne, JOC, Tran, TT, Secomb, JL, Lundgren, LE, Farley, ORL, Newton, RU, and Sheppard, JM. Maximal strength training improves surfboard sprint and endurance paddling performance in competitive and recreational surfers. J Strength Cond Res 31(1): 244-253, 2017-Upper-body (UB) strength has very high correlations with faster surfboard paddling speeds. However, there is no research examining the effects of improving UB strength has on surfboard paddling ability. This study aimed to determine the influence that improvements in UB closed-kinetic chain maximal strength have on surfboard paddling in both competitive and recreational surfers. Seventeen competitive and recreational male surfers (29.7 ± 7.7 years, 177.4 ± 7.4 cm, 76.7 ± 9.9 kg) participated in a repeated-measures, parallel control study design. Anthropometry; 5-, 10-, and 15-m sprint; and 400-m endurance surfboard paddling tests along with pull-up and dip 1 repetition maximum strength tests were assessed pre- and postintervention. Subjects in the training group performed 5 weeks of maximal strength training in the pull-up and dip. Differences between the training and control groups were examined postintervention. The training group increased their speed over the 5-, 10-, and 15-m sprint, whereas the control group became slower (d = 0.71, 0.51, and 0.4, respectively). The training group also displayed faster endurance paddling performance compared with the control group (d = 0.72). Short-term exposure to maximal strength training elicits improvements in paddling performance measures. However, the magnitude of performance increases seems to be dependent on initial strength levels with differential responses between strong and weaker athletes. Although a longer maximal strength training period may have produced more significant paddling improvements in stronger subjects, practitioners are unlikely to have any more than 5 weeks in an uninterrupted block with competitive surfing athletes. This study reveals that a "threshold" level of maximal strength that if possessed, short-term maximal strength training may only provide little improvement in paddling performance.
Interhemispheric integration in visual search
Shipp, Stewart
2011-01-01
The search task of Luck, Hillyard, Mangun and Gazzaniga (1989) was optimised to test for the presence of a bilateral field advantage in the visual search capabilities of normal subjects. The modified design used geometrically regular arrays of 2, 4 or 8 items restricted to hemifields delineated by the vertical or horizontal meridian; the target, if present, appeared at one of two fixed positions per quadrant at an eccentricity of 11 deg. Group and individual performance data were analysed in terms of the slope of response time against display-size functions (‘RT slope’). Averaging performance across all conditions save display mode (bilateral vs. unilateral) revealed a significant bilateral advantage in the form of a 21% increase in apparent item scanning speed for target detection; in the absence of a target, bilateral displays gave a 5% increase in speed that was not significant. Factor analysis by ANOVA confirmed this main effect of display mode, and also revealed several higher order interactions with display geometry, indicating that the bilateral advantage was masked at certain target positions by a crowding-like effect. In a numerical model of search efficiency (i.e. RT slope), bilateral advantage was parameterised by an interhemispheric ‘transfer factor’ (T) that governs the strength of the ipsilateral representation of distractors, and modifies the level of intrahemispheric competition with the target. The factor T was found to be higher in superior field than inferior field; this result held for the modelled data of each individual subject, as well as the group, representing a uniform tendency for the bilateral advantage to be more prominent in inferior field. In fact statistical analysis and modelling of search efficiency showed that the geometrical display factors (target polar and quadrantic location, and associated crowding effects) were all remarkably consistent across subjects. Greater variability was inferred within a fixed, decisional component of response time, with individual subjects capable of opposite hemifield biases. The results are interpretable by a guided search model of spatial attention – a first, parallel stage guiding selection by a second, serial stage – with the proviso that the first stage is relatively insular within each hemisphere. The bilateral advantage in search efficiency can then be attributed to a relative gain in target weight within the initial parallel stage, owing to a reduction in distractor competition mediated specifically by intrahemispheric circuitry. In the absence of a target there is no effective guidance, and hence no basis for a bilateral advantage to enhance search efficiency; the equivalence of scanning speed for the two display modes (bilateral and unilateral) implies a unitary second-stage process mediated via efficient interhemispheric integration. PMID:21640738
Interhemispheric integration in visual search.
Shipp, Stewart
2011-07-01
The search task of Luck, Hillyard, Mangun and Gazzaniga (1989) was optimised to test for the presence of a bilateral field advantage in the visual search capabilities of normal subjects. The modified design used geometrically regular arrays of 2, 4 or 8 items restricted to hemifields delineated by the vertical or horizontal meridian; the target, if present, appeared at one of two fixed positions per quadrant at an eccentricity of 11 deg. Group and individual performance data were analysed in terms of the slope of response time against display-size functions ('RT slope'). Averaging performance across all conditions save display mode (bilateral vs. unilateral) revealed a significant bilateral advantage in the form of a 21% increase in apparent item scanning speed for target detection; in the absence of a target, bilateral displays gave a 5% increase in speed that was not significant. Factor analysis by ANOVA confirmed this main effect of display mode, and also revealed several higher order interactions with display geometry, indicating that the bilateral advantage was masked at certain target positions by a crowding-like effect. In a numerical model of search efficiency (i.e. RT slope), bilateral advantage was parameterised by an interhemispheric 'transfer factor' (T) that governs the strength of the ipsilateral representation of distractors, and modifies the level of intrahemispheric competition with the target. The factor T was found to be higher in superior field than inferior field; this result held for the modelled data of each individual subject, as well as the group, representing a uniform tendency for the bilateral advantage to be more prominent in inferior field. In fact statistical analysis and modelling of search efficiency showed that the geometrical display factors (target polar and quadrantic location, and associated crowding effects) were all remarkably consistent across subjects. Greater variability was inferred within a fixed, decisional component of response time, with individual subjects capable of opposite hemifield biases. The results are interpretable by a guided search model of spatial attention - a first, parallel stage guiding selection by a second, serial stage - with the proviso that the first stage is relatively insular within each hemisphere. The bilateral advantage in search efficiency can then be attributed to a relative gain in target weight within the initial parallel stage, owing to a reduction in distractor competition mediated specifically by intrahemispheric circuitry. In the absence of a target there is no effective guidance, and hence no basis for a bilateral advantage to enhance search efficiency; the equivalence of scanning speed for the two display modes (bilateral and unilateral) implies a unitary second-stage process mediated via efficient interhemispheric integration. Copyright © 2011 Elsevier Ltd. All rights reserved.
Ghafouri, H R; Mosharaf-Dehkordi, M; Afzalan, B
2017-07-01
A simulation-optimization model is proposed for identifying the characteristics of local immiscible NAPL contaminant sources inside aquifers. This model employs the UTCHEM 9.0 software as its simulator for solving the governing equations associated with the multi-phase flow in porous media. As the optimization model, a novel two-level saturation based Imperialist Competitive Algorithm (ICA) is proposed to estimate the parameters of contaminant sources. The first level consists of three parallel independent ICAs and plays as a pre-conditioner for the second level which is a single modified ICA. The ICA in the second level is modified by dividing each country into a number of provinces (smaller parts). Similar to countries in the classical ICA, these provinces are optimized by the assimilation, competition, and revolution steps in the ICA. To increase the diversity of populations, a new approach named knock the base method is proposed. The performance and accuracy of the simulation-optimization model is assessed by solving a set of two and three-dimensional problems considering the effects of different parameters such as the grid size, rock heterogeneity and designated monitoring networks. The obtained numerical results indicate that using this simulation-optimization model provides accurate results at a less number of iterations when compared with the model employing the classical one-level ICA. Copyright © 2017 Elsevier B.V. All rights reserved.
Multirate-based fast parallel algorithms for 2-D DHT-based real-valued discrete Gabor transform.
Tao, Liang; Kwan, Hon Keung
2012-07-01
Novel algorithms for the multirate and fast parallel implementation of the 2-D discrete Hartley transform (DHT)-based real-valued discrete Gabor transform (RDGT) and its inverse transform are presented in this paper. A 2-D multirate-based analysis convolver bank is designed for the 2-D RDGT, and a 2-D multirate-based synthesis convolver bank is designed for the 2-D inverse RDGT. The parallel channels in each of the two convolver banks have a unified structure and can apply the 2-D fast DHT algorithm to speed up their computations. The computational complexity of each parallel channel is low and is independent of the Gabor oversampling rate. All the 2-D RDGT coefficients of an image are computed in parallel during the analysis process and can be reconstructed in parallel during the synthesis process. The computational complexity and time of the proposed parallel algorithms are analyzed and compared with those of the existing fastest algorithms for 2-D discrete Gabor transforms. The results indicate that the proposed algorithms are the fastest, which make them attractive for real-time image processing.
A Comparative Analysis of the Use of Competitive Intelligence Tools in a Multinational Corporation
ERIC Educational Resources Information Center
Breese-Vitelli, Jennifer
2011-01-01
With the growth of the global economy, organizations large and small are increasingly recognizing that competitive intelligence (CI) is essential to compete in industry. Competitive intelligence is used to gain an advantage in commerce and is useful for analyzing a company's strategic industry position. To remain current and profitable,…
Why Competition May Discourage Students from Learning. A Behavioral Economic Analysis.
ERIC Educational Resources Information Center
Wang, X. Henry; Yang, Bill Z.
2003-01-01
Combines the concept of self-worth in sociology and educational psychology with economic modeling to analyze the influence of competition on student learning. Finds, for example, that students prone to negative self-worth are motivated not to study hard in courses involving strong competition, thereby adopting a strategy of winning by not losing.…
Project X: competitive intelligence data mining and analysis
NASA Astrophysics Data System (ADS)
Gilmore, John F.; Pagels, Michael A.; Palk, Justin
2001-03-01
Competitive Intelligence (CI) is a systematic and ethical program for gathering and analyzing information about your competitors' activities and general business trends to further your own company's goals. CI allows companies to gather extensive information on their competitors and to analyze what the competition is doing in order to maintain or gain a competitive edge. In commercial business this potentially translates into millions of dollars in annual savings or losses. The Internet provides an overwhelming portal of information for CI analysis. The problem is how a company can automate the translation of voluminous information into valuable and actionable knowledge. This paper describes Project X, an agent-based data mining system specifically developed for extracting and analyzing competitive information from the Internet. Project X gathers CI information from a variety of sources including online newspapers, corporate websites, industry sector reporting sites, speech archiving sites, video news casts, stock news sites, weather sites, and rumor sites. It uses individual industry specific (e.g., pharmaceutical, financial, aerospace, etc.) commercial sector ontologies to form the knowledge filtering and discovery structures/content required to filter and identify valuable competitive knowledge. Project X is described in detail and an example competitive intelligence case is shown demonstrating the system's performance and utility for business intelligence.
Toward an Extension of Decision Analysis to Competitive Situations.
1985-12-01
order to deal with competition may ease the use of non- von Neumann-Morgenstern utility. This leads to our secondary goal of questioning expected...While von WInterfeldt [1980] attempted a 5 (more detailed analysis using three separate decision trees, one for each side In the dispute, he felt that...rationality generally used In game theory derives from the same roots as the calculated rationality of Decision Analysis, von Neumann and
Njunjić, Iva; Perrard, Adrien; Hendriks, Kasper; Schilthuizen, Menno; Perreau, Michel; Merckx, Vincent; Baylac, Michel; Deharveng, Louis
2018-01-01
The genus Anthroherpon Reitter, 1889 exhibits the most pronounced troglomorphic characters among Coleoptera, and represents one of the most spectacular radiations of subterranean beetles. However, radiation, diversification, and biogeography of this genus have never been studied in a phylogenetic context. This study provides a comprehensive evolutionary analysis of the Anthroherpon radiation, using a dated molecular phylogeny as a framework for understanding Anthroherpon diversification, reconstructing the ancestral range, and exploring troglomorphic diversity. Based on 16 species and 22 subspecies, i.e. the majority of Anthroherpon diversity, we reconstructed the phylogeny using Bayesian analysis of six loci, both mitochondrial and nuclear, comprising a total of 4143 nucleotides. In parallel, a morphometric analysis was carried out with 79 landmarks on the body that were subjected to geometric morphometrics. We optimized morphometric features to phylogeny, in order to recognize the way troglomorphy was expressed in different clades of the tree, and did character evolution analyses. Finally, we reconstructed the ancestral range of the genus using BioGeoBEARS. Besides further elucidating the suprageneric classification of the East-Mediterranean Leptodirini, our main findings also show that Anthroherpon dates back to the Early Miocene (ca. 22 MYA) and that the genus diversified entirely underground. Biogeographic reconstruction of the ancestral range shows the origin of the genus in the area comprising three high mountains in western Montenegro, which is in the accordance with the available data on the paleogeography of the Balkan Peninsula. Character evolution analysis indicates that troglomorphic morphometric traits in Anthroherpon mostly evolve neutrally but may diverge adaptively under syntopic competition.
Changing competition in health care marketing: a method for analysis and strategic planning.
Ellis, B; Brockman, B K
1993-01-01
As the cost and importance of healthcare continue to increase, competition in the medical industry is taking new forms and becoming more intense. The driving trends behind this competition are analyzed in the framework of Porter's Five Forces of Competition Model. The authors then discuss how the widely accepted strategies of cost, differentiation, focus, and domestication can be utilized to counter the implications of these trends and how to capitalize on opportunities in medical practice in the 1990's.
2014-01-01
Background Split-mouth randomized controlled trials (RCTs) are popular in oral health research. Meta-analyses frequently include trials of both split-mouth and parallel-arm designs to derive combined intervention effects. However, carry-over effects may induce bias in split- mouth RCTs. We aimed to assess whether intervention effect estimates differ between split- mouth and parallel-arm RCTs investigating the same questions. Methods We performed a meta-epidemiological study. We systematically reviewed meta- analyses including both split-mouth and parallel-arm RCTs with binary or continuous outcomes published up to February 2013. Two independent authors selected studies and extracted data. We used a two-step approach to quantify the differences between split-mouth and parallel-arm RCTs: for each meta-analysis. First, we derived ratios of odds ratios (ROR) for dichotomous data and differences in standardized mean differences (∆SMD) for continuous data; second, we pooled RORs or ∆SMDs across meta-analyses by random-effects meta-analysis models. Results We selected 18 systematic reviews, for 15 meta-analyses with binary outcomes (28 split-mouth and 28 parallel-arm RCTs) and 19 meta-analyses with continuous outcomes (28 split-mouth and 28 parallel-arm RCTs). Effect estimates did not differ between split-mouth and parallel-arm RCTs (mean ROR, 0.96, 95% confidence interval 0.52–1.80; mean ∆SMD, 0.08, -0.14–0.30). Conclusions Our study did not provide sufficient evidence for a difference in intervention effect estimates derived from split-mouth and parallel-arm RCTs. Authors should consider including split-mouth RCTs in their meta-analyses with suitable and appropriate analysis. PMID:24886043
A Dual Super-Element Domain Decomposition Approach for Parallel Nonlinear Finite Element Analysis
NASA Astrophysics Data System (ADS)
Jokhio, G. A.; Izzuddin, B. A.
2015-05-01
This article presents a new domain decomposition method for nonlinear finite element analysis introducing the concept of dual partition super-elements. The method extends ideas from the displacement frame method and is ideally suited for parallel nonlinear static/dynamic analysis of structural systems. In the new method, domain decomposition is realized by replacing one or more subdomains in a "parent system," each with a placeholder super-element, where the subdomains are processed separately as "child partitions," each wrapped by a dual super-element along the partition boundary. The analysis of the overall system, including the satisfaction of equilibrium and compatibility at all partition boundaries, is realized through direct communication between all pairs of placeholder and dual super-elements. The proposed method has particular advantages for matrix solution methods based on the frontal scheme, and can be readily implemented for existing finite element analysis programs to achieve parallelization on distributed memory systems with minimal intervention, thus overcoming memory bottlenecks typically faced in the analysis of large-scale problems. Several examples are presented in this article which demonstrate the computational benefits of the proposed parallel domain decomposition approach and its applicability to the nonlinear structural analysis of realistic structural systems.
Burtscher, Johannes; Furtner, Marco; Sachse, Pierre; Burtscher, Martin
2011-06-01
This study validated a German version of the Sport Motivation Scale (SMS28) and investigated the sex-specific and age-related differences in motivation of competitive mountain runners. Translation and cross-cultural adaptation of the SMS28 was based on translation and back-translation methodology. Acceptable validity of the German version of the SMS28 was indicated by the high correlations (.81 to .98) of scores on the seven subscales for the English and German versions completed by 15 subjects. Motivation analysis was performed with 127 competitive male and female mountain runners. The seven subscales of the German version showed good internal consistency (Cronbach's coefficient alphas .70 to .85). Findings on motivation of competitive mountain runners were a decline across age groups of Intrinsic motivation toward accomplishment for both sexes and an age-related decline of External regulation only for females. These motivational changes might well be associated with the observed diminishing numbers of older participants in mountain running competitions.
USDA-ARS?s Scientific Manuscript database
A method is demonstrated for analysis of vitamin D-fortified dietary supplements that eliminates virtually all chemical pretreatment prior to analysis, and is referred to as a ‘dilute and shoot’ method. Three mass spectrometers, in parallel, plus a UV detector, an evaporative light scattering detec...
Simplified Parallel Domain Traversal
DOE Office of Scientific and Technical Information (OSTI.GOV)
Erickson III, David J
2011-01-01
Many data-intensive scientific analysis techniques require global domain traversal, which over the years has been a bottleneck for efficient parallelization across distributed-memory architectures. Inspired by MapReduce and other simplified parallel programming approaches, we have designed DStep, a flexible system that greatly simplifies efficient parallelization of domain traversal techniques at scale. In order to deliver both simplicity to users as well as scalability on HPC platforms, we introduce a novel two-tiered communication architecture for managing and exploiting asynchronous communication loads. We also integrate our design with advanced parallel I/O techniques that operate directly on native simulation output. We demonstrate DStep bymore » performing teleconnection analysis across ensemble runs of terascale atmospheric CO{sub 2} and climate data, and we show scalability results on up to 65,536 IBM BlueGene/P cores.« less
Software Design for Real-Time Systems on Parallel Computers: Formal Specifications.
1996-04-01
This research investigated the important issues related to the analysis and design of real - time systems targeted to parallel architectures. In...particular, the software specification models for real - time systems on parallel architectures were evaluated. A survey of current formal methods for...uniprocessor real - time systems specifications was conducted to determine their extensibility in specifying real - time systems on parallel architectures. In
Analysis and performance of paralleling circuits for modular inverter-converter systems
NASA Technical Reports Server (NTRS)
Birchenough, A. G.; Gourash, F.
1972-01-01
As part of a modular inverter-converter development program, control techniques were developed to provide load sharing among paralleled inverters or converters. An analysis of the requirements of paralleling circuits and a discussion of the circuits developed and their performance are included in this report. The current sharing was within 5.6 percent of rated-load current for the ac modules and 7.4 percent for the dc modules for an initial output voltage unbalance of 5 volts.
ERIC Educational Resources Information Center
Dolinsky, Arthur L.; Quazi, Hesan A.
1994-01-01
Importance-performance analysis, a marketing research technique using analysis of consumer attitudes toward salient product or service attributes, is found useful for colleges and universities in developing marketing strategies, particularly when competition is considered as an important dimension. Data are drawn from a survey of 252 students at 1…
Evaluation of field performance of poplar clones using selected competition indices.
Chandler Brodie; D.S. DeBell
2004-01-01
Use of competition indices in the analysis of forestry experiments may improve detection and understanding of treatment effects, and thereby improve the application of results. In this paper, we compared the performance of eight indices in an analysis of a spacing trial of four Populus clones planted in pure and mixed clonal plots. Indices were...
Hierarchical Parallelization of Gene Differential Association Analysis
2011-01-01
Background Microarray gene differential expression analysis is a widely used technique that deals with high dimensional data and is computationally intensive for permutation-based procedures. Microarray gene differential association analysis is even more computationally demanding and must take advantage of multicore computing technology, which is the driving force behind increasing compute power in recent years. In this paper, we present a two-layer hierarchical parallel implementation of gene differential association analysis. It takes advantage of both fine- and coarse-grain (with granularity defined by the frequency of communication) parallelism in order to effectively leverage the non-uniform nature of parallel processing available in the cutting-edge systems of today. Results Our results show that this hierarchical strategy matches data sharing behavior to the properties of the underlying hardware, thereby reducing the memory and bandwidth needs of the application. The resulting improved efficiency reduces computation time and allows the gene differential association analysis code to scale its execution with the number of processors. The code and biological data used in this study are downloadable from http://www.urmc.rochester.edu/biostat/people/faculty/hu.cfm. Conclusions The performance sweet spot occurs when using a number of threads per MPI process that allows the working sets of the corresponding MPI processes running on the multicore to fit within the machine cache. Hence, we suggest that practitioners follow this principle in selecting the appropriate number of MPI processes and threads within each MPI process for their cluster configurations. We believe that the principles of this hierarchical approach to parallelization can be utilized in the parallelization of other computationally demanding kernels. PMID:21936916
Hierarchical parallelization of gene differential association analysis.
Needham, Mark; Hu, Rui; Dwarkadas, Sandhya; Qiu, Xing
2011-09-21
Microarray gene differential expression analysis is a widely used technique that deals with high dimensional data and is computationally intensive for permutation-based procedures. Microarray gene differential association analysis is even more computationally demanding and must take advantage of multicore computing technology, which is the driving force behind increasing compute power in recent years. In this paper, we present a two-layer hierarchical parallel implementation of gene differential association analysis. It takes advantage of both fine- and coarse-grain (with granularity defined by the frequency of communication) parallelism in order to effectively leverage the non-uniform nature of parallel processing available in the cutting-edge systems of today. Our results show that this hierarchical strategy matches data sharing behavior to the properties of the underlying hardware, thereby reducing the memory and bandwidth needs of the application. The resulting improved efficiency reduces computation time and allows the gene differential association analysis code to scale its execution with the number of processors. The code and biological data used in this study are downloadable from http://www.urmc.rochester.edu/biostat/people/faculty/hu.cfm. The performance sweet spot occurs when using a number of threads per MPI process that allows the working sets of the corresponding MPI processes running on the multicore to fit within the machine cache. Hence, we suggest that practitioners follow this principle in selecting the appropriate number of MPI processes and threads within each MPI process for their cluster configurations. We believe that the principles of this hierarchical approach to parallelization can be utilized in the parallelization of other computationally demanding kernels.
NASA Astrophysics Data System (ADS)
Yu, Tong; Ye, Yue-li
2018-05-01
In accordance with the related data of Statistical Yearbook of Jiangxi (2007—2016), conduct analysis on the development situation of inbound tourist source market in Jiangxi based on geographic concentration index and market competition status. The result shows: when the geographic concentration index of the inbound tourism market in Jiangxi presents an increasing decline trend, the tourism-generating countries of the inbound tourism in Jiangxi are getting more and more disperse, the tourist markets present the diversified feature and the inbound tourism market tends to be stable; besides, the analysis result of the market competition status shows that the inbound tourism development in Jiangxi has transformed from the rapid development to stable development.
Evolution and Growth Competition of Salt Fingers in Saline Lake with Slight Wind Shear
NASA Astrophysics Data System (ADS)
Yang, Ray-Yeng; Hwung, Hwung-Hweng; Shugan, Igor
2010-05-01
Since the discover of double-diffusive convection by Stommel, Arons & Blanchard (1956), 'evidence has accumulated for the widespread presence of double-diffusion throughout the ocean' and for its 'significant effects on global water-mass structure and the thermohaline convection' (Schmitt, 1998). The salt-fingering form of double-diffusion has particularly attracted interest because of salt-finger convection being now widely recognized as an important mechanism for mixing heat and salt both vertically and laterally in the ocean and saline lake. In oceanographic situations or saline lake where salt fingers may be an important mechanism for the transport of heat and salt in the vertical, velocity shears may also be present. Salt finger convection is analogous to Bénard convection in that the kinetic energy of the motions is obtained from the potential energy stored in the unstable distribution of a stratifying component. On the basis of the thermal analogy it is of interest to discover whether salt fingers are converted into two-dimensional sheets by the wind shear, and how the vertical fluxes of heat and salt are changed by the wind shear. Salt finger convection under the effect of steady wind shear is theoretically examined in this paper. The evolution of developing in the presence of a vertical density gradient disturbance and the horizontal Couette flow is considered near the onset of salt fingers in the saline lake under a moderate rate of wind shear. We use velocity as the basic variable and solve the pressure Poisson equation in terms of the associated Green function. Growth competition between the longitudinal rolls (LR) and the transverse rolls (TR), whose axes are respectively in the direction parallel to and perpendicular to the Couette flow, is investigated by the weakly nonlinear analysis of coupled-mode equations. The results show that the TR mode is characterized in some range of the effective Rayleigh number, and that the stability is dominated by the LR mode in the system. KEY WORDS: evolution, saline lake, salt finger convection, wind shear, growth competition, longitudinal rolls, transverse rolls, coupled-mode equations.
Analysis of the thermal balance characteristics for multiple-connected piezoelectric transformers.
Park, Joung-Hu; Cho, Bo-Hyung; Choi, Sung-Jin; Lee, Sang-Min
2009-08-01
Because the amount of power that a piezoelectric transformer (PT) can handle is limited, multiple connections of PTs are necessary for the power-capacity improvement of PT-applications. In the connection, thermal imbalance between the PTs should be prevented to avoid the thermal runaway of each PT. The thermal balance of the multiple-connected PTs is dominantly affected by the electrothermal characteristics of individual PTs. In this paper, the thermal balance of both parallel-parallel and parallel-series connections are analyzed by electrical model parameters. For quantitative analysis, the thermal-balance effects are estimated by the simulation of the mechanical loss ratio between the PTs. The analysis results show that with PTs of similar characteristics, the parallel-series connection has better thermal balance characteristics due to the reduced mechanical loss of the higher temperature PT. For experimental verification of the analysis, a hardware-prototype test of a Cs-Lp type 40 W adapter system with radial-vibration mode PTs has been performed.
Interactive Fringe Analysis System: Applications To Moire Contourogram And Interferogram
NASA Astrophysics Data System (ADS)
Yatagai, T.; Idesawa, M.; Yamaashi, Y.; Suzuki, M.
1982-10-01
A general purpose fringe pattern processing facility was developed in order to analyze moire photographs used for scoliosis diagnoses and interferometric patterns in optical shops. A TV camera reads a fringe profile to be analyzed, and peaks of the fringe are detected by a microcomputer. Fringe peak correction and fringe order determination are performed with the man-machine interactive software developed. A light pen facility and an image digitizer are employed for interaction. In the case of two-dimensional fringe analysis, we analyze independently analysis lines parallel to each other and a reference line perpendicular to the parallel analysis lines. Fringe orders of parallel analysis lines are uniquely determined by using the fringe order of the reference line. Some results of analysis of moire contourograms, interferometric testing of silicon wafers, and holographic measurement of thermal deformation are presented.
Is competition needed for ecological character displacement? Does displacement decrease competition?
Abrams, Peter A.; Cortez, Michael H.
2015-01-01
Interspecific competition for resources is generally considered to be the selective force driving ecological character displacement, and displacement is assumed to reduce competition. Skeptics of the prevalence of character displacement often cite lack of evidence of competition. The present article uses a simple model to examine whether competition is needed for character displacement and whether displacement reduces competition. It treats systems with competing resources, and considers cases when only one consumer evolves. It quantifies competition using several different measures. The analysis shows that selection for divergence of consumers occurs regardless of the level of between‐resource competition or whether the indirect interaction between the consumers is competition (−,−), mutualism (+,+), or contramensalism (+,−). Also, divergent evolution always decreases the equilibrium population size of the evolving consumer. Whether divergence of one consumer reduces or increases the impact of a subsequent perturbation of the other consumer depends on the parameters and the method chosen for measuring competition. Divergence in mutualistic interactions may reduce beneficial effects of subsequent increases in the other consumer's population. The evolutionary response is driven by an increase in the relative abundance of the resource the consumer catches more rapidly. Such an increase can occur under several types of interaction. PMID:26548922
The case for teaming on the ALS-STME program
NASA Technical Reports Server (NTRS)
Morea, S. F.
1991-01-01
The analysis concludes that the nation needs to proceed with a new LOX/LH2 rocket engine program now. It is also concluded that open competition now will have deleterious impacts on the competitive viability of the liquid rocket engine industry. Teaming, however, provides a way to solve todays concerns while enhancing the option for open competition in the future.
Krägeloh, Christian U; Medvedev, Oleg N; Hill, Erin M; Webster, Craig S; Booth, Roger J; Henning, Marcus A
2018-01-01
Measuring competitiveness is necessary to fully understand variables affecting student learning. The 14-item Revised Competitiveness Index has become a widely used measure to assess trait competitiveness. The current study reports on a Rasch analysis to investigate the psychometric properties of the Revised Competitiveness Index and to improve its precision for international comparisons. Students were recruited from medical studies at a university in New Zealand, undergraduate health sciences courses at another New Zealand university, and a psychology undergraduate class at a university in the United States. Rasch model estimate parameters were affected by local dependency and item misfit. Best fit to the Rasch model (χ 2 (20) = 15.86, p = .73, person separation index = .95) was obtained for the Enjoyment of Competition subscale after combining locally dependent items into a subtest and discarding the highly misfitting Item 9. The only modifications required to obtain a suitable fit (χ 2 (25) = 25.81, p = .42, person separation index = .77) for the Contentiousness subscale were a subtest to combine two locally dependent items and splitting this subtest by country to deal with differential item functioning. The results support reliability and internal construct validity of the modified Revised Competitiveness Index. Precision of the measure may be enhanced using the ordinal-to-interval conversion algorithms presented here, allowing the use of parametric statistics without breaking fundamental statistical assumptions.
Pricing and competition in the private dental market in Finland.
Widström, E; Väisänen, A; Mikkola, H
2011-06-01
To investigate how the prices were set in private dental care, which factors determined prices and whether the recent National Dental Care Reform had increased competition in the dental care market in Finland. A questionnaire to all full time private dentists (n = 1,121) in the ten largest cities. Characteristics of the practice, prices charged, price setting, perceived competition and expectations for the practices were requested. The response rate was 59.6%. Correlation analysis (Pearson's) was used to study relationships between the prices of different treatment items. Linear regression analysis was used to study determinants of the price of a one surface filling. Most dentists' fee schedules were based on the price of a one surface filling and updated annually. Changes in practice costs calculated by the dentists' professional association and information on average prices charged on dental treatments in the country influenced pricing. High price levels were associated with specialisation, working in a group practice, working close to many other practices or in a town with a dental school. Less than half of the respondents had faced competition in dental services and price competition was insignificant. Price setting followed traditional patterns and private markets in dental services were not found to be very competitive.
Frerichs, H.; Schmitz, Oliver; Evans, Todd; ...
2015-07-13
High resolution plasma transport simulations with the EMC3-EIRENE code have been performed to address the parallel plasma flow structure in the boundary of a poloidal divertor configuration with non-axisymmetric perturbations at DIII-D. Simulation results show that a checkerboard pattern of flows with alternating direction is generated inside the separatrix. This pattern is aligned with the position of the main resonances (i.e. where the safety factor is equal to rational values q = m/n for a perturbation field with base mode number n): m pairs of alternating forward and backward flow channel exist for each resonance. The poloidal oscillations are alignedmore » with the subharmonic Melnikov function, which indicates that the plasma flow is generated by parallel pressure gradients along perturbed field lines. Lastly, an additional scrape-off layer-like domain is introduced by the perturbed separatrix which guides field lines from the interior to the divertor targets, resulting in an enhanced outward flow that is consistent with the experimentally observed particle pump-out effect. However, while the lobe structure of the perturbed separatrix is very well reflected in the temperature profile, the same lobes can appear to be smaller in the flow profile due to a competition between high upstream pressure and downstream particle sources driving flows in opposite directions.« less
Comparison of multihardware parallel implementations for a phase unwrapping algorithm
NASA Astrophysics Data System (ADS)
Hernandez-Lopez, Francisco Javier; Rivera, Mariano; Salazar-Garibay, Adan; Legarda-Sáenz, Ricardo
2018-04-01
Phase unwrapping is an important problem in the areas of optical metrology, synthetic aperture radar (SAR) image analysis, and magnetic resonance imaging (MRI) analysis. These images are becoming larger in size and, particularly, the availability and need for processing of SAR and MRI data have increased significantly with the acquisition of remote sensing data and the popularization of magnetic resonators in clinical diagnosis. Therefore, it is important to develop faster and accurate phase unwrapping algorithms. We propose a parallel multigrid algorithm of a phase unwrapping method named accumulation of residual maps, which builds on a serial algorithm that consists of the minimization of a cost function; minimization achieved by means of a serial Gauss-Seidel kind algorithm. Our algorithm also optimizes the original cost function, but unlike the original work, our algorithm is a parallel Jacobi class with alternated minimizations. This strategy is known as the chessboard type, where red pixels can be updated in parallel at same iteration since they are independent. Similarly, black pixels can be updated in parallel in an alternating iteration. We present parallel implementations of our algorithm for different parallel multicore architecture such as CPU-multicore, Xeon Phi coprocessor, and Nvidia graphics processing unit. In all the cases, we obtain a superior performance of our parallel algorithm when compared with the original serial version. In addition, we present a detailed comparative performance of the developed parallel versions.
NASA Technical Reports Server (NTRS)
Storaasli, Olaf O. (Editor); Housner, Jerrold M. (Editor)
1993-01-01
Computing speed is leaping forward by several orders of magnitude each decade. Engineers and scientists gathered at a NASA Langley symposium to discuss these exciting trends as they apply to parallel computational methods for large-scale structural analysis and design. Among the topics discussed were: large-scale static analysis; dynamic, transient, and thermal analysis; domain decomposition (substructuring); and nonlinear and numerical methods.
Physics Structure Analysis of Parallel Waves Concept of Physics Teacher Candidate
NASA Astrophysics Data System (ADS)
Sarwi, S.; Supardi, K. I.; Linuwih, S.
2017-04-01
The aim of this research was to find a parallel structure concept of wave physics and the factors that influence on the formation of parallel conceptions of physics teacher candidates. The method used qualitative research which types of cross-sectional design. These subjects were five of the third semester of basic physics and six of the fifth semester of wave course students. Data collection techniques used think aloud and written tests. Quantitative data were analysed with descriptive technique-percentage. The data analysis technique for belief and be aware of answers uses an explanatory analysis. Results of the research include: 1) the structure of the concept can be displayed through the illustration of a map containing the theoretical core, supplements the theory and phenomena that occur daily; 2) the trend of parallel conception of wave physics have been identified on the stationary waves, resonance of the sound and the propagation of transverse electromagnetic waves; 3) the influence on the parallel conception that reading textbooks less comprehensive and knowledge is partial understanding as forming the structure of the theory.
Hematological and Biochemical Parameters in Elite Soccer Players During A Competitive Half Season
Anđelković, Marija; Baralić, Ivana; Đorđević, Brižita; Stevuljević, Jelena Kotur; Radivojević, Nenad; Dikić, Nenad; Škodrić, Sanja Radojević; Stojković, Mirjana
2015-01-01
Summary Background The purpose of the present study was to report and discuss the hematological and biochemical behavior of elite soccer players, in order to get more insight in the physiological characteristics of these sportsmen and to provide trainers and sports doctors with useful indicators. Methods Nineteen male soccer players volunteered to participate in this study. We followed the young elite soccer players during a competitive half season. Venous blood samples were collected between 9:00 and 10:00 a.m. after an overnight fast (10 h) at baseline, after 45 and 90 days and hematological and biochemical parameters were measured. Results Hemoglobin and hematocrit levels were significantly reduced over the observational period (p<0.05), but erythrocyte count and iron levels remained unchanged. Bilirubin and ferritin levels significantly increased in response to regular soccer training (p<0.05). We observed a significant decrease in muscle enzyme plasma activity during the 90 days study period. ANOVA analysis revealed a significant increase in the leukocyte and neutrophil counts (p<0.05), in parallel with a significant decrease in the lymphocyte count (p<0.05) after the observational period of 90 days. Conclusions Elite soccer players are characterized by significant changes in biochemical and hematological parameters over the half season, which are linked to training workload, as well as adaptation induced by the soccer training. Although the values of the measured parameters fell within the reference range, regular monitoring of the biochemical and hematological parameters is fundamental for the identification of a healthy status and related optimal performances by sport doctors and trainers and selection of a correct workload by trainers. PMID:28356856
NASA Technical Reports Server (NTRS)
Tilton, James C.
1988-01-01
Image segmentation can be a key step in data compression and image analysis. However, the segmentation results produced by most previous approaches to region growing are suspect because they depend on the order in which portions of the image are processed. An iterative parallel segmentation algorithm avoids this problem by performing globally best merges first. Such a segmentation approach, and two implementations of the approach on NASA's Massively Parallel Processor (MPP) are described. Application of the segmentation approach to data compression and image analysis is then described, and results of such application are given for a LANDSAT Thematic Mapper image.
A mechanism for efficient debugging of parallel programs
DOE Office of Scientific and Technical Information (OSTI.GOV)
Miller, B.P.; Choi, J.D.
1988-01-01
This paper addresses the design and implementation of an integrated debugging system for parallel programs running on shared memory multi-processors (SMMP). The authors describe the use of flowback analysis to provide information on causal relationships between events in a program's execution without re-executing the program for debugging. The authors introduce a mechanism called incremental tracing that, by using semantic analyses of the debugged program, makes the flowback analysis practical with only a small amount of trace generated during execution. The extend flowback analysis to apply to parallel programs and describe a method to detect race conditions in the interactions ofmore » the co-operating processes.« less
Competition Among Reputations in the 2D Sznajd Model: Spontaneous Emergence of Democratic States
NASA Astrophysics Data System (ADS)
Crokidakis, Nuno; Forgerini, Fabricio L.
2012-04-01
We propose a modification in the Sznajd sociophysics model defined on the square lattice. For this purpose, we consider reputation—a mechanism limiting the agents' persuasive power. The reputation is introduced as a time-dependent score, which can be positive or negative. This mechanism avoids dictatorship (full consensus, all spins parallel) for a wide range of model parameters. We consider two different situations: case 1, in which the agents' reputation increases for each persuaded neighbor, and case 2, in which the agents' reputation increases for each persuasion and decreases when a neighbor keeps his opinion. Our results show that the introduction of reputation avoids full consensus even for initial densities of up spins greater than 1/2. The relaxation times follow a log-normal-like distribution in both cases, but they are larger in case 2 due to the competition among reputations. In addition, we show that the usual phase transition occurs and depends on the initial concentration d of individuals with the same opinion, but the critical points d c in the two cases are different.
NASA Astrophysics Data System (ADS)
An, Fengwei; Akazawa, Toshinobu; Yamasaki, Shogo; Chen, Lei; Jürgen Mattausch, Hans
2015-04-01
This paper reports a VLSI realization of learning vector quantization (LVQ) with high flexibility for different applications. It is based on a hardware/software (HW/SW) co-design concept for on-chip learning and recognition and designed as a SoC in 180 nm CMOS. The time consuming nearest Euclidean distance search in the LVQ algorithm’s competition layer is efficiently implemented as a pipeline with parallel p-word input. Since neuron number in the competition layer, weight values, input and output number are scalable, the requirements of many different applications can be satisfied without hardware changes. Classification of a d-dimensional input vector is completed in n × \\lceil d/p \\rceil + R clock cycles, where R is the pipeline depth, and n is the number of reference feature vectors (FVs). Adjustment of stored reference FVs during learning is done by the embedded 32-bit RISC CPU, because this operation is not time critical. The high flexibility is verified by the application of human detection with different numbers for the dimensionality of the FVs.
Xyce parallel electronic simulator users guide, version 6.1
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keiter, Eric R; Mei, Ting; Russo, Thomas V.
This manual describes the use of the Xyce Parallel Electronic Simulator. Xyce has been designed as a SPICE-compatible, high-performance analog circuit simulator, and has been written to support the simulation needs of the Sandia National Laboratories electrical designers. This development has focused on improving capability over the current state-of-the-art in the following areas; Capability to solve extremely large circuit problems by supporting large-scale parallel computing platforms (up to thousands of processors). This includes support for most popular parallel and serial computers; A differential-algebraic-equation (DAE) formulation, which better isolates the device model package from solver algorithms. This allows one to developmore » new types of analysis without requiring the implementation of analysis-specific device models; Device models that are specifically tailored to meet Sandia's needs, including some radiationaware devices (for Sandia users only); and Object-oriented code design and implementation using modern coding practices. Xyce is a parallel code in the most general sense of the phrase-a message passing parallel implementation-which allows it to run efficiently a wide range of computing platforms. These include serial, shared-memory and distributed-memory parallel platforms. Attention has been paid to the specific nature of circuit-simulation problems to ensure that optimal parallel efficiency is achieved as the number of processors grows.« less
Xyce parallel electronic simulator users' guide, Version 6.0.1.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keiter, Eric R; Mei, Ting; Russo, Thomas V.
This manual describes the use of the Xyce Parallel Electronic Simulator. Xyce has been designed as a SPICE-compatible, high-performance analog circuit simulator, and has been written to support the simulation needs of the Sandia National Laboratories electrical designers. This development has focused on improving capability over the current state-of-the-art in the following areas: Capability to solve extremely large circuit problems by supporting large-scale parallel computing platforms (up to thousands of processors). This includes support for most popular parallel and serial computers. A differential-algebraic-equation (DAE) formulation, which better isolates the device model package from solver algorithms. This allows one to developmore » new types of analysis without requiring the implementation of analysis-specific device models. Device models that are specifically tailored to meet Sandias needs, including some radiationaware devices (for Sandia users only). Object-oriented code design and implementation using modern coding practices. Xyce is a parallel code in the most general sense of the phrase a message passing parallel implementation which allows it to run efficiently a wide range of computing platforms. These include serial, shared-memory and distributed-memory parallel platforms. Attention has been paid to the specific nature of circuit-simulation problems to ensure that optimal parallel efficiency is achieved as the number of processors grows.« less
Xyce parallel electronic simulator users guide, version 6.0.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keiter, Eric R; Mei, Ting; Russo, Thomas V.
This manual describes the use of the Xyce Parallel Electronic Simulator. Xyce has been designed as a SPICE-compatible, high-performance analog circuit simulator, and has been written to support the simulation needs of the Sandia National Laboratories electrical designers. This development has focused on improving capability over the current state-of-the-art in the following areas: Capability to solve extremely large circuit problems by supporting large-scale parallel computing platforms (up to thousands of processors). This includes support for most popular parallel and serial computers. A differential-algebraic-equation (DAE) formulation, which better isolates the device model package from solver algorithms. This allows one to developmore » new types of analysis without requiring the implementation of analysis-specific device models. Device models that are specifically tailored to meet Sandias needs, including some radiationaware devices (for Sandia users only). Object-oriented code design and implementation using modern coding practices. Xyce is a parallel code in the most general sense of the phrase a message passing parallel implementation which allows it to run efficiently a wide range of computing platforms. These include serial, shared-memory and distributed-memory parallel platforms. Attention has been paid to the specific nature of circuit-simulation problems to ensure that optimal parallel efficiency is achieved as the number of processors grows.« less
Cravana, Cristina; Medica, P.; Ragonese, G.; Fazio, E.
2017-01-01
Aim: To investigate the effects of training sessions on circulating β-endorphin changes in sport horses before and after competition and to ascertain whether competition would affect this response. Materials and Methods: A total of 24 trained jumping horses were randomly assigned to one of two training groups: Group A (competing) and Group B (not competing). To determined plasma β-endorphin concentrations, two pre- and post-competition training weeks at aerobic workout and two competitive show jumping event days at anaerobic workout were measured before, 5 and 30 min after exercise. Exercise intensity is described using lactate concentrations and heart rate. The circuit design, intensity, and duration of training sessions were the same for both groups. Results: In Group A, one-way analysis of variance for repeated measures (RM-ANOVA) showed significant effects of exercise on β-endorphin changes (F=14.41; p<0.001), only in the post-competition training sessions, while in Group B showed no significant effects. Two-way RM-ANOVA showed, after post-competition training sessions, a significant difference between Group A and Group B (F=6.235; p=0.023), with higher β-endorphin changes in Group A, compared to Group B. During the competitive show jumping sessions, one-way RM ANOVA showed significant effects of exercise on β-endorphin changes (F=51.10; p<0.001). The statistical analysis, in Group A, showed a significant difference between post-competition training and competitive exercise (F=6.32; p=0.024) with higher β-endorphin values in competitive sessions compared to those of post-competition training. Conclusion: Lactate concentrations seem to be the main factors being correlated with the raise of β-endorphin during anaerobic exercise of competitive events. Exercise of low intensity, as well as that one of training sessions, does not appear to stimulate a significant increased release of β-endorphin and it may depend on the duration of the exercise program. Moreover, the responses during exercise in the course of post-competition training sessions seem to be significantly different from those the pre-competition training. These data show that the preliminary competitive stress induced additional significant changes of β-endorphin pattern. It would reflect the need of a long-lasting modulation of fatigue and pain perception related to the effect of an additional physical and mental effort for the consecutive competitive and training sessions. PMID:28246449
Multidisciplinary Optimization Methods for Aircraft Preliminary Design
NASA Technical Reports Server (NTRS)
Kroo, Ilan; Altus, Steve; Braun, Robert; Gage, Peter; Sobieski, Ian
1994-01-01
This paper describes a research program aimed at improved methods for multidisciplinary design and optimization of large-scale aeronautical systems. The research involves new approaches to system decomposition, interdisciplinary communication, and methods of exploiting coarse-grained parallelism for analysis and optimization. A new architecture, that involves a tight coupling between optimization and analysis, is intended to improve efficiency while simplifying the structure of multidisciplinary, computation-intensive design problems involving many analysis disciplines and perhaps hundreds of design variables. Work in two areas is described here: system decomposition using compatibility constraints to simplify the analysis structure and take advantage of coarse-grained parallelism; and collaborative optimization, a decomposition of the optimization process to permit parallel design and to simplify interdisciplinary communication requirements.
Incorporating health care quality into health antitrust law
2008-01-01
Background Antitrust authorities treat price as a proxy for hospital quality since health care quality is difficult to observe. As the ability to measure quality improved, more research became necessary to investigate the relationship between hospital market power and patient outcomes. This paper examines the impact of hospital competition on the quality of care as measured by the risk-adjusted mortality rates with the hospital as the unit of analysis. The study separately examines the effect of competition on non-profit hospitals. Methods We use California Office of Statewide Health Planning and Development (OSHPD) data from 1997 through 2002. Empirical model is a cross-sectional study of 373 hospitals. Regression analysis is used to estimate the relationship between Coronary Artery Bypass Graft (CABG) risk-adjusted mortality rates and hospital competition. Results Regression results show lower risk-adjusted mortality rates in the presence of a more competitive environment. This result holds for all alternative hospital market definitions. Non-profit hospitals do not have better patient outcomes than investor-owned hospitals. However, they tend to provide better quality in less competitive environments. CABG volume did not have a significant effect on patient outcomes. Conclusion Quality should be incorporated into the antitrust analysis. When mergers lead to higher prices and lower quality, thus lower social welfare, the antitrust challenge of hospital mergers is warranted. The impact of lower hospital competition on quality of care delivered by non-profit hospitals is ambiguous. PMID:18430219
Solving Integer Programs from Dependence and Synchronization Problems
1993-03-01
DEFF.NSNE Solving Integer Programs from Dependence and Synchronization Problems Jaspal Subhlok March 1993 CMU-CS-93-130 School of Computer ScienceT IC...method Is an exact and efficient way of solving integer programming problems arising in dependence and synchronization analysis of parallel programs...7/;- p Keywords: Exact dependence tesing, integer programming. parallelilzng compilers, parallel program analysis, synchronization analysis Solving
Multiscaling Edge Effects in an Agent-based Money Emergence Model
NASA Astrophysics Data System (ADS)
Oświęcimka, P.; Drożdż, S.; Gębarowski, R.; Górski, A. Z.; Kwapień, J.
An agent-based computational economical toy model for the emergence of money from the initial barter trading, inspired by Menger's postulate that money can spontaneously emerge in a commodity exchange economy, is extensively studied. The model considered, while manageable, is significantly complex, however. It is already able to reveal phenomena that can be interpreted as emergence and collapse of money as well as the related competition effects. In particular, it is shown that - as an extra emerging effect - the money lifetimes near the critical threshold value develop multiscaling, which allow one to set parallels to critical phenomena and, thus, to the real financial markets.
[Relating costs to activities in hospitals. Use of internal cost accounting].
Stavem, K
1995-01-10
During the last few years hospital cost accounting has become widespread in many countries, in parallel with increasing cost pressure, greater competition and new financing schemes. Cost accounting has been used in the manufacturing industry for many years. Costs can be related to activities and production, e.g. by the costing of procedures, episodes of care and other internally defined cost objectives. Norwegian hospitals have lagged behind in the adoption of cost accounting. They ought to act quickly if they want to be prepared for possible changes in health care financing. The benefits can be considerable to a hospital operating in a rapidly changing health care environment.
Preliminary results of the large experimental wind turbine phase of the national wind energy program
NASA Technical Reports Server (NTRS)
Thomas, R. L.; Sholes, T.; Sholes, J. E.
1975-01-01
The preliminary results of two projects in the development phase of reliable wind turbines designed to supply cost-competitive electrical energy were discussed. An experimental 100 kW wind turbine design and its status are first reviewed. The results of two parallel design studies for determining the configurations and power levels for wind turbines with minimum energy costs are also discussed. These studies predict wind energy costs of 1.5 to 7 cents per kW-h for wind turbines produced in quantities of 100 to 1000 per year and located at sites having average winds of 12 to 18 mph.
A review of Curtiss-Wright rotary engine developments with respect to general aviation potential
NASA Technical Reports Server (NTRS)
Jones, C.
1979-01-01
Aviation related rotary (Wankel-type) engine tests, possible growth directions and relevant developments at Curtiss-Wright have been reviewed. Automotive rotary engines including stratified charge are described and flight test results of rotary aircraft engines are presented. The current 300 HP engine prototype shows basic durability and competitive performance potential. Recent parallel developments have separately confirmed the geometric advantages of the rotary engine for direct injected unthrottled stratified charge. Specific fuel consumption equal to or better than pre- or swirl-chamber diesels, low emission and multi-fuel capability have been shown by rig tests of similar rotary engine.
SAPNEW: Parallel finite element code for thin shell structures on the Alliant FX/80
NASA Astrophysics Data System (ADS)
Kamat, Manohar P.; Watson, Brian C.
1992-02-01
The results of a research activity aimed at providing a finite element capability for analyzing turbo-machinery bladed-disk assemblies in a vector/parallel processing environment are summarized. Analysis of aircraft turbofan engines is very computationally intensive. The performance limit of modern day computers with a single processing unit was estimated at 3 billions of floating point operations per second (3 gigaflops). In view of this limit of a sequential unit, performance rates higher than 3 gigaflops can be achieved only through vectorization and/or parallelization as on Alliant FX/80. Accordingly, the efforts of this critically needed research were geared towards developing and evaluating parallel finite element methods for static and vibration analysis. A special purpose code, named with the acronym SAPNEW, performs static and eigen analysis of multi-degree-of-freedom blade models built-up from flat thin shell elements.
Tutorial: Parallel Computing of Simulation Models for Risk Analysis.
Reilly, Allison C; Staid, Andrea; Gao, Michael; Guikema, Seth D
2016-10-01
Simulation models are widely used in risk analysis to study the effects of uncertainties on outcomes of interest in complex problems. Often, these models are computationally complex and time consuming to run. This latter point may be at odds with time-sensitive evaluations or may limit the number of parameters that are considered. In this article, we give an introductory tutorial focused on parallelizing simulation code to better leverage modern computing hardware, enabling risk analysts to better utilize simulation-based methods for quantifying uncertainty in practice. This article is aimed primarily at risk analysts who use simulation methods but do not yet utilize parallelization to decrease the computational burden of these models. The discussion is focused on conceptual aspects of embarrassingly parallel computer code and software considerations. Two complementary examples are shown using the languages MATLAB and R. A brief discussion of hardware considerations is located in the Appendix. © 2016 Society for Risk Analysis.
SAPNEW: Parallel finite element code for thin shell structures on the Alliant FX/80
NASA Technical Reports Server (NTRS)
Kamat, Manohar P.; Watson, Brian C.
1992-01-01
The results of a research activity aimed at providing a finite element capability for analyzing turbo-machinery bladed-disk assemblies in a vector/parallel processing environment are summarized. Analysis of aircraft turbofan engines is very computationally intensive. The performance limit of modern day computers with a single processing unit was estimated at 3 billions of floating point operations per second (3 gigaflops). In view of this limit of a sequential unit, performance rates higher than 3 gigaflops can be achieved only through vectorization and/or parallelization as on Alliant FX/80. Accordingly, the efforts of this critically needed research were geared towards developing and evaluating parallel finite element methods for static and vibration analysis. A special purpose code, named with the acronym SAPNEW, performs static and eigen analysis of multi-degree-of-freedom blade models built-up from flat thin shell elements.
Concurrent Probabilistic Simulation of High Temperature Composite Structural Response
NASA Technical Reports Server (NTRS)
Abdi, Frank
1996-01-01
A computational structural/material analysis and design tool which would meet industry's future demand for expedience and reduced cost is presented. This unique software 'GENOA' is dedicated to parallel and high speed analysis to perform probabilistic evaluation of high temperature composite response of aerospace systems. The development is based on detailed integration and modification of diverse fields of specialized analysis techniques and mathematical models to combine their latest innovative capabilities into a commercially viable software package. The technique is specifically designed to exploit the availability of processors to perform computationally intense probabilistic analysis assessing uncertainties in structural reliability analysis and composite micromechanics. The primary objectives which were achieved in performing the development were: (1) Utilization of the power of parallel processing and static/dynamic load balancing optimization to make the complex simulation of structure, material and processing of high temperature composite affordable; (2) Computational integration and synchronization of probabilistic mathematics, structural/material mechanics and parallel computing; (3) Implementation of an innovative multi-level domain decomposition technique to identify the inherent parallelism, and increasing convergence rates through high- and low-level processor assignment; (4) Creating the framework for Portable Paralleled architecture for the machine independent Multi Instruction Multi Data, (MIMD), Single Instruction Multi Data (SIMD), hybrid and distributed workstation type of computers; and (5) Market evaluation. The results of Phase-2 effort provides a good basis for continuation and warrants Phase-3 government, and industry partnership.
Improved packing of protein side chains with parallel ant colonies
2014-01-01
Introduction The accurate packing of protein side chains is important for many computational biology problems, such as ab initio protein structure prediction, homology modelling, and protein design and ligand docking applications. Many of existing solutions are modelled as a computational optimisation problem. As well as the design of search algorithms, most solutions suffer from an inaccurate energy function for judging whether a prediction is good or bad. Even if the search has found the lowest energy, there is no certainty of obtaining the protein structures with correct side chains. Methods We present a side-chain modelling method, pacoPacker, which uses a parallel ant colony optimisation strategy based on sharing a single pheromone matrix. This parallel approach combines different sources of energy functions and generates protein side-chain conformations with the lowest energies jointly determined by the various energy functions. We further optimised the selected rotamers to construct subrotamer by rotamer minimisation, which reasonably improved the discreteness of the rotamer library. Results We focused on improving the accuracy of side-chain conformation prediction. For a testing set of 442 proteins, 87.19% of X1 and 77.11% of X12 angles were predicted correctly within 40° of the X-ray positions. We compared the accuracy of pacoPacker with state-of-the-art methods, such as CIS-RR and SCWRL4. We analysed the results from different perspectives, in terms of protein chain and individual residues. In this comprehensive benchmark testing, 51.5% of proteins within a length of 400 amino acids predicted by pacoPacker were superior to the results of CIS-RR and SCWRL4 simultaneously. Finally, we also showed the advantage of using the subrotamers strategy. All results confirmed that our parallel approach is competitive to state-of-the-art solutions for packing side chains. Conclusions This parallel approach combines various sources of searching intelligence and energy functions to pack protein side chains. It provides a frame-work for combining different inaccuracy/usefulness objective functions by designing parallel heuristic search algorithms. PMID:25474164
NASA Astrophysics Data System (ADS)
Lee, Po-Chih; Lee, Jyh-Jone
2012-06-01
This paper presents the analysis of three parallel manipulators with Schoenflies-motion. Each parallel manipulator possesses two limbs in structure and the end-effector has three DOFs (degree of freedom) in the translational motion and one DOF in rotational motion about a given direction axis with respect to the world coordinate system. The three isoconstrained parallel manipulators have the structures denoted as C{u/u}UwHw-//-C{v/v}UwHw, CuR{u/u}Uhw-//-CvR{v/v}Uhw and CuPuUhw-//-CvPvUhw. The kinematic equations are first introduced for each manipulator. Then, Jacobian matrix, singularity, workspace, and performance index for each mechanism are subsequently derived and analysed for the first time. The results can be helpful for the engineers to evaluate such kind of parallel robots for possible application in industry where pick-and-place motion is required.
Has competition increased hospital technical efficiency?
Lee, Keon-Hyung; Park, Jungwon; Lim, Seunghoo; Park, Sang-Chul
2015-01-01
Hospital competition and managed care have affected the hospital industry in various ways including technical efficiency. Hospital efficiency has become an important topic, and it is important to properly measure hospital efficiency in order to evaluate the impact of policies on the hospital industry. The primary independent variable is hospital competition. By using the 2001-2004 inpatient discharge data from Florida, we calculate the degree of hospital competition in Florida for 4 years. Hospital efficiency scores are developed using the Data Envelopment Analysis and by using the selected input and output variables from the American Hospital Association's Annual Survey of Hospitals for those acute care general hospitals in Florida. By using the hospital efficiency score as a dependent variable, we analyze the effects of hospital competition on hospital efficiency from 2001 to 2004 and find that when a hospital was located in a less competitive market in 2003, its technical efficiency score was lower than those in a more competitive market.
Carbon pricing, nuclear power and electricity markets
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cameron, R.; Keppler, J. H.
2012-07-01
In 2010, the NEA in conjunction with the International Energy Agency produced an analysis of the Projected Costs of Electricity for almost 200 power plants, covering nuclear, fossil fuel and renewable electricity generation. That analysis used lifetime costs to consider the merits of each technology. However, the lifetime cost analysis is less applicable in liberalised markets and does not look specifically at the viewpoint of the private investor. A follow-up NEA assessment of the competitiveness of nuclear energy against coal- and gas-fired generation under carbon pricing has considered just this question. The economic competition in electricity markets is today betweenmore » nuclear energy and gas-fired power generation, with coal-fired power generation not being competitive as soon as even modest carbon pricing is introduced. Whether nuclear energy or natural gas comes out ahead in their competition depends on a number of assumptions, which, while all entirely reasonable, yield very different outcomes. The analysis in this study has been developed on the basis of daily data from European power markets over the last five-year period. Three different methodologies, a Profit Analysis looking at historic returns over the past five years, an Investment Analysis projecting the conditions of the past five years over the lifetime of plants and a Carbon Tax Analysis (differentiating the Investment Analysis for different carbon prices) look at the issue of competitiveness from different angles. They show that the competitiveness of nuclear energy depends on a number of variables which in different configurations determine whether electricity produced from nuclear power or from CCGTs generates higher profits for its investors. These are overnight costs, financing costs, gas prices, carbon prices, profit margins (or mark-ups), the amount of coal with carbon capture and electricity prices. This paper will present the outcomes of the analysis in the context of a liberalised electricity market, looking at the impact of the seven key variables and provide conclusions on the portfolio that a utility would be advised to maintain, given the need to limit risks but also to move to low carbon power generation. Such portfolio diversification would not only limit financial investor risk, but also a number of non-financial risks (climate change, security of supply, accidents). (authors)« less
Research on the competitiveness of high-tech industries in northeast China
NASA Astrophysics Data System (ADS)
Liu, Lei; Wang, Yang; Wang, Ming-Quan; Xiao, Yan-Bo; Gao, Ming
2017-06-01
Based on characteristics of high-tech industry in Northeast China, high-tech industry competitiveness index system was developed, and the competitiveness of high-tech industry was evaluated through principal component analysis and location quotient method. The results showed that the scale of high-tech industry in Northeast China as a whole was small, and presented a decreasing trend for the proportion in the country. The competitiveness of high-tech industry in Northeast China lagged far behind that of the eastern and central regions. The high-tech industry competitiveness of Liaoning, Jilin and Heilongjiang provinces in China ranked 15, 19 and 21, respectively. The manufacture of medicine in Jilin province, and the manufacture of aircraft and spacecraft and the related equipment in Liaoning and Heilongjiang provinces had high competitive advantage, but the manufacture of electronic equipment and communication equipment and the manufacture of computers and office equipment was lack of competitiveness. The development suggestions were put forward to improve the competitiveness of high-tech industries in Northeast China.
Spatial competition dynamics between reef corals under ocean acidification.
Horwitz, Rael; Hoogenboom, Mia O; Fine, Maoz
2017-01-09
Climate change, including ocean acidification (OA), represents a major threat to coral-reef ecosystems. Although previous experiments have shown that OA can negatively affect the fitness of reef corals, these have not included the long-term effects of competition for space on coral growth rates. Our multispecies year-long study subjected reef-building corals from the Gulf of Aqaba (Red Sea) to competitive interactions under present-day ocean pH (pH 8.1) and predicted end-of-century ocean pH (pH 7.6). Results showed coral growth is significantly impeded by OA under intraspecific competition for five out of six study species. Reduced growth from OA, however, is negligible when growth is already suppressed in the presence of interspecific competition. Using a spatial competition model, our analysis indicates shifts in the competitive hierarchy and a decrease in overall coral cover under lowered pH. Collectively, our case study demonstrates how modified competitive performance under increasing OA will in all likelihood change the composition, structure and functionality of reef coral communities.
Spatial competition dynamics between reef corals under ocean acidification
NASA Astrophysics Data System (ADS)
Horwitz, Rael; Hoogenboom, Mia O.; Fine, Maoz
2017-01-01
Climate change, including ocean acidification (OA), represents a major threat to coral-reef ecosystems. Although previous experiments have shown that OA can negatively affect the fitness of reef corals, these have not included the long-term effects of competition for space on coral growth rates. Our multispecies year-long study subjected reef-building corals from the Gulf of Aqaba (Red Sea) to competitive interactions under present-day ocean pH (pH 8.1) and predicted end-of-century ocean pH (pH 7.6). Results showed coral growth is significantly impeded by OA under intraspecific competition for five out of six study species. Reduced growth from OA, however, is negligible when growth is already suppressed in the presence of interspecific competition. Using a spatial competition model, our analysis indicates shifts in the competitive hierarchy and a decrease in overall coral cover under lowered pH. Collectively, our case study demonstrates how modified competitive performance under increasing OA will in all likelihood change the composition, structure and functionality of reef coral communities.
Parallel Computing for Probabilistic Response Analysis of High Temperature Composites
NASA Technical Reports Server (NTRS)
Sues, R. H.; Lua, Y. J.; Smith, M. D.
1994-01-01
The objective of this Phase I research was to establish the required software and hardware strategies to achieve large scale parallelism in solving PCM problems. To meet this objective, several investigations were conducted. First, we identified the multiple levels of parallelism in PCM and the computational strategies to exploit these parallelisms. Next, several software and hardware efficiency investigations were conducted. These involved the use of three different parallel programming paradigms and solution of two example problems on both a shared-memory multiprocessor and a distributed-memory network of workstations.
Hierarchical Parallelism in Finite Difference Analysis of Heat Conduction
NASA Technical Reports Server (NTRS)
Padovan, Joseph; Krishna, Lala; Gute, Douglas
1997-01-01
Based on the concept of hierarchical parallelism, this research effort resulted in highly efficient parallel solution strategies for very large scale heat conduction problems. Overall, the method of hierarchical parallelism involves the partitioning of thermal models into several substructured levels wherein an optimal balance into various associated bandwidths is achieved. The details are described in this report. Overall, the report is organized into two parts. Part 1 describes the parallel modelling methodology and associated multilevel direct, iterative and mixed solution schemes. Part 2 establishes both the formal and computational properties of the scheme.
Managed competition: an analysis of consumer concerns. The Working Group on Managed Competition.
1994-01-01
Advocates for health care reform (representing a broad range of constituencies) raise serious concerns about the ability of managed competition to meet the health care needs of the American people. Similarities in managed competition proposals include establishment of a collective purchasing authority, creation of health plans, standardization of rules and requirements, and limitation on tax subsidies. Managed competition proposals vary as to whether they call for true universality, meaningful cost containment, and fair financing. The article raises questions about managed competition, including the technical feasibility; the link to employment; the role for insurance companies; severing the link between insurance and income, age, or health status; comprehensive benefits; cost containment; the role for managed care; universality of coverage; and the role for insurance companies to make treatment decisions.
Review of the BCI Competition IV
Tangermann, Michael; Müller, Klaus-Robert; Aertsen, Ad; Birbaumer, Niels; Braun, Christoph; Brunner, Clemens; Leeb, Robert; Mehring, Carsten; Miller, Kai J.; Müller-Putz, Gernot R.; Nolte, Guido; Pfurtscheller, Gert; Preissl, Hubert; Schalk, Gerwin; Schlögl, Alois; Vidaurre, Carmen; Waldert, Stephan; Blankertz, Benjamin
2012-01-01
The BCI competition IV stands in the tradition of prior BCI competitions that aim to provide high quality neuroscientific data for open access to the scientific community. As experienced already in prior competitions not only scientists from the narrow field of BCI compete, but scholars with a broad variety of backgrounds and nationalities. They include high specialists as well as students. The goals of all BCI competitions have always been to challenge with respect to novel paradigms and complex data. We report on the following challenges: (1) asynchronous data, (2) synthetic, (3) multi-class continuous data, (4) session-to-session transfer, (5) directionally modulated MEG, (6) finger movements recorded by ECoG. As after past competitions, our hope is that winning entries may enhance the analysis methods of future BCIs. PMID:22811657
NASA Astrophysics Data System (ADS)
Božiková, Lucia; Šnircová, Jana
2016-06-01
In this article we introduce a model of sustainable competitiveness, which we created on the basis of a long term study of literature and analysis. This article is divided into several parts. In the first part, we will introduce the problem of competitiveness and sustainable competitiveness. The second part is focused on the basic aspects for the creation of the model. In the third part the model itself is introduced and also an explanation and description of the mode is given.
A comparison of parallel and diverging screw angles in the stability of locked plate constructs.
Wähnert, D; Windolf, M; Brianza, S; Rothstock, S; Radtke, R; Brighenti, V; Schwieger, K
2011-09-01
We investigated the static and cyclical strength of parallel and angulated locking plate screws using rigid polyurethane foam (0.32 g/cm(3)) and bovine cancellous bone blocks. Custom-made stainless steel plates with two conically threaded screw holes with different angulations (parallel, 10° and 20° divergent) and 5 mm self-tapping locking screws underwent pull-out and cyclical pull and bending tests. The bovine cancellous blocks were only subjected to static pull-out testing. We also performed finite element analysis for the static pull-out test of the parallel and 20° configurations. In both the foam model and the bovine cancellous bone we found the significantly highest pull-out force for the parallel constructs. In the finite element analysis there was a 47% more damage in the 20° divergent constructs than in the parallel configuration. Under cyclical loading, the mean number of cycles to failure was significantly higher for the parallel group, followed by the 10° and 20° divergent configurations. In our laboratory setting we clearly showed the biomechanical disadvantage of a diverging locking screw angle under static and cyclical loading.
Dimensionality Assessment of Ordered Polytomous Items with Parallel Analysis
ERIC Educational Resources Information Center
Timmerman, Marieke E.; Lorenzo-Seva, Urbano
2011-01-01
Parallel analysis (PA) is an often-recommended approach for assessment of the dimensionality of a variable set. PA is known in different variants, which may yield different dimensionality indications. In this article, the authors considered the most appropriate PA procedure to assess the number of common factors underlying ordered polytomously…
Comparison of sampling techniques for Bayesian parameter estimation
NASA Astrophysics Data System (ADS)
Allison, Rupert; Dunkley, Joanna
2014-02-01
The posterior probability distribution for a set of model parameters encodes all that the data have to tell us in the context of a given model; it is the fundamental quantity for Bayesian parameter estimation. In order to infer the posterior probability distribution we have to decide how to explore parameter space. Here we compare three prescriptions for how parameter space is navigated, discussing their relative merits. We consider Metropolis-Hasting sampling, nested sampling and affine-invariant ensemble Markov chain Monte Carlo (MCMC) sampling. We focus on their performance on toy-model Gaussian likelihoods and on a real-world cosmological data set. We outline the sampling algorithms themselves and elaborate on performance diagnostics such as convergence time, scope for parallelization, dimensional scaling, requisite tunings and suitability for non-Gaussian distributions. We find that nested sampling delivers high-fidelity estimates for posterior statistics at low computational cost, and should be adopted in favour of Metropolis-Hastings in many cases. Affine-invariant MCMC is competitive when computing clusters can be utilized for massive parallelization. Affine-invariant MCMC and existing extensions to nested sampling naturally probe multimodal and curving distributions.
Quality of life, coach behaviour and competitive anxiety in Winter Youth Olympic Games participants.
Ledochowski, Larissa; Unterrainer, Christine; Ruedl, Gerhard; Schnitzer, Martin; Kopp, Martin
2012-12-01
To ensure the highest technical performance, speed, safety, excellent control and to improve competitive performance, a successful regulation of competitive anxiety is necessary. Therefore, it seems crucial to identify factors influencing competitive anxiety of adolescent athletes. Research suggests that people reporting high quality of life are more capable to cope with stressful and challenging situations than others. The aim of this study was to investigate the impact of quality of life, the involvement of parents in sports career and coach's leadership behaviour on competitive anxiety in Winter Youth Olympic Games participants. During the first Winter Youth Olympic Games 2012 in Innsbruck/Austria, 662 (316 women) participants completed questionnaires and single items to assess quality of life, coach's leadership behaviour, parental involvement in sports career and competitive anxiety. Multiple regression analysis revealed positive influences of high quality of life and useful coach instruction on competitive anxiety. The relationship between quality of life, coach behaviour and competitive anxiety in young elite athletes competing at the first Winter Youth Olympic Games should be considered in long-term programmes for reducing competitive stress.
An Industry Analysis of the MBA Market and the Competitive Positioning of the GSBPP
2007-03-01
THIS PAGE INTENTIONALLY LEFT BLANK 1 I. INTRODUCTION Traditional business schools face threats to their competitive positioning as the educational...MBA market were competition between business schools , buyers of business education including both students and employers, faculty as the key...Representative Core Course Requirement While business schools consider it their mission to educate students for their entire career, they are
NASA Technical Reports Server (NTRS)
Nguyen, Duc T.; Storaasli, Olaf O.; Qin, Jiangning; Qamar, Ramzi
1994-01-01
An automatic differentiation tool (ADIFOR) is incorporated into a finite element based structural analysis program for shape and non-shape design sensitivity analysis of structural systems. The entire analysis and sensitivity procedures are parallelized and vectorized for high performance computation. Small scale examples to verify the accuracy of the proposed program and a medium scale example to demonstrate the parallel vector performance on multiple CRAY C90 processors are included.
A Study on Standard Competition with Network Effect Based on Evolutionary Game Model
NASA Astrophysics Data System (ADS)
Wang, Ye; Wang, Bingdong; Li, Kangning
Owing to networks widespread in modern society, standard competition with network effect is now endowed with new connotation. This paper aims to study the impact of network effect on standard competition; it is organized in the mode of "introduction-model setup-equilibrium analysis-conclusion". Starting from a well-structured model of evolutionary game, it is then extended to a dynamic analysis. This article proves both theoretically and empirically that whether or not a standard can lead the market trends depends on the utility it would bring, and the author also discusses some advisable strategies revolving around the two factors of initial position and border break.
Automatic recognition of vector and parallel operations in a higher level language
NASA Technical Reports Server (NTRS)
Schneck, P. B.
1971-01-01
A compiler for recognizing statements of a FORTRAN program which are suited for fast execution on a parallel or pipeline machine such as Illiac-4, Star or ASC is described. The technique employs interval analysis to provide flow information to the vector/parallel recognizer. Where profitable the compiler changes scalar variables to subscripted variables. The output of the compiler is an extension to FORTRAN which shows parallel and vector operations explicitly.
Methods for design and evaluation of parallel computating systems (The PISCES project)
NASA Technical Reports Server (NTRS)
Pratt, Terrence W.; Wise, Robert; Haught, Mary JO
1989-01-01
The PISCES project started in 1984 under the sponsorship of the NASA Computational Structural Mechanics (CSM) program. A PISCES 1 programming environment and parallel FORTRAN were implemented in 1984 for the DEC VAX (using UNIX processes to simulate parallel processes). This system was used for experimentation with parallel programs for scientific applications and AI (dynamic scene analysis) applications. PISCES 1 was ported to a network of Apollo workstations by N. Fitzgerald.
National Combustion Code Parallel Performance Enhancements
NASA Technical Reports Server (NTRS)
Quealy, Angela; Benyo, Theresa (Technical Monitor)
2002-01-01
The National Combustion Code (NCC) is being developed by an industry-government team for the design and analysis of combustion systems. The unstructured grid, reacting flow code uses a distributed memory, message passing model for its parallel implementation. The focus of the present effort has been to improve the performance of the NCC code to meet combustor designer requirements for model accuracy and analysis turnaround time. Improving the performance of this code contributes significantly to the overall reduction in time and cost of the combustor design cycle. This report describes recent parallel processing modifications to NCC that have improved the parallel scalability of the code, enabling a two hour turnaround for a 1.3 million element fully reacting combustion simulation on an SGI Origin 2000.
Multi-species coexistence in Lotka-Volterra competitive systems with crowding effects.
Gavina, Maica Krizna A; Tahara, Takeru; Tainaka, Kei-Ichi; Ito, Hiromu; Morita, Satoru; Ichinose, Genki; Okabe, Takuya; Togashi, Tatsuya; Nagatani, Takashi; Yoshimura, Jin
2018-01-19
Classical Lotka-Volterra (LV) competition equation has shown that coexistence of competitive species is only possible when intraspecific competition is stronger than interspecific competition, i.e., the species inhibit their own growth more than the growth of the other species. Note that density effect is assumed to be linear in a classical LV equation. In contrast, in wild populations we can observed that mortality rate often increases when population density is very high, known as crowding effects. Under this perspective, the aggregation models of competitive species have been developed, adding the additional reduction in growth rates at high population densities. This study shows that the coexistence of a few species is promoted. However, an unsolved question is the coexistence of many competitive species often observed in natural communities. Here, we build an LV competition equation with a nonlinear crowding effect. Our results show that under a weak crowding effect, stable coexistence of many species becomes plausible, unlike the previous aggregation model. An analysis indicates that increased mortality rate under high density works as elevated intraspecific competition leading to the coexistence. This may be another mechanism for the coexistence of many competitive species leading high species diversity in nature.
A longitudinal analysis of women's salivary testosterone and intrasexual competitiveness.
Hahn, Amanda C; Fisher, Claire I; Cobey, Kelly D; DeBruine, Lisa M; Jones, Benedict C
2016-02-01
Research on within-subject changes in women's intrasexual competitiveness has generally focused on possible relationships between women's intrasexual competitiveness and estimates of their fertility. While this approach is useful for testing hypotheses about the adaptive function of changes in women's intrasexual competitiveness, it offers little insight into the proximate mechanisms through which such changes might occur. To investigate this issue, we carried out a longitudinal study of the hormonal correlates of changes in intrasexual competitiveness in a large sample of heterosexual women (N=136). Each woman provided saliva samples and completed an intrasexual competitiveness questionnaire in five weekly test sessions. Multilevel modeling of these data revealed a significant, positive within-subject effect of testosterone on intrasexual competitiveness, indicating that women reported greater intrasexual competitiveness when testosterone was high. By contrast, there were no significant effects of estradiol, progesterone, estradiol-to-progesterone ratio, or cortisol and no significant effects of any hormones on reported relationship jealousy. This is the first study to demonstrate correlated changes in measured testosterone levels and women's reported intrasexual competitiveness, implicating testosterone in the regulation of women's intrasexual competitiveness. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.
Everhart, Damian; Neff, Donna; Al-Amin, Mona; Nogle, June; Weech-Maldonado, Robert
2013-01-01
Hospitals facing financial uncertainty have sought to reduce nurse staffing as a way to increase profitability. However, nurse staffing has been found to be important in terms of quality of patient care and nursing-related outcomes. Nurse staffing can provide a competitive advantage to hospitals and as a result of better financial performance, particularly in more competitive markets. In this study, we build on the Resource-Based View of the Firm to determine the effect of nurse staffing on total profit margin in more competitive and less competitive hospital markets in Florida. By combining a Florida statewide nursing survey with the American Hospital Association Annual Survey and the Area Resource File, three separate multivariate linear regression models were conducted to determine the effect of nurse staffing on financial performance while accounting for market competitiveness. The analysis was limited to acute care hospitals. Nurse staffing levels had a positive association with financial performance (β = 3.3, p = .02) in competitive hospital markets, but no significant association was found in less competitive hospital markets. Hospitals in more competitive hospital markets should reconsider reducing nursing staff, as these cost-cutting measures may be inefficient and negatively affect financial performance.
An Examination of Regional Competitiveness: Early Findings from Banten, Indonesia
NASA Astrophysics Data System (ADS)
Holis, Y. M.; Syabri, I.; Prabatmojo, H.
2018-05-01
Over time, the regional development planning paradigm continues to change procedural, substantive, actor and institutional aspects. The increasing globalization and decentralized governance systems will continue to determine how a country or region can compete and even be able to take advantage of the positive value of economic globalization. This certainly provides challenges and opportunities for the renewal of regional development concepts, in particular, the concept of regional competitiveness. This concept still lacks a scientific basis and its interpretation is still in debate. To date, the clear scientific basis is the concepts of corporate and national competitiveness. Whereas, the concept of competitiveness at the meso-level, namely the competitiveness of the region, becomes very important. Regional competitiveness prepares a region and to survive in response to the more open dynamics of economic globalization and the system of decentralization of authority in Indonesia. The objective of this research is to complement the concept of competitiveness which is still at the level of microeconomics (business theory) and macroeconomy (theory of growth) with the concept of competitiveness at the regional level that focuses on (i) finding determinant factors at the regional level in Indonesia; (ii) profiling regional competitiveness in several regions; and (iii) assessing the role of local government (institutional and actor) on determinants of regional competitiveness. This research is carried out by using a mixed-methods approach with a concurrent triangulation strategy model. The research follows the stages of literature study to identify the determinant factors of regional competitiveness relevant to the purpose of research, followed by descriptive analysis of the variables and selected by statistics through Analytical Network Process (ANP) to become the determinant factor of competitiveness. In accordance with the concept and definition of regional competitiveness, this research develops five main indicators determining regional competitiveness and its 30 variables. These indicators are regional economy; manpower and human resources; productive business environment; infrastructure; natural resources and environment; and banking and financial institutions. The data used are primary and secondary data by compiling from the Central Statistics Agency (BPS) and questionnaires to the Regional Development Planning Agency (BAPPEDA) following by in-depth interviews with experts. This research uses the case study of Banten Province. The main reason is that Banten has varied areas, ranging from developed cities to lagging regions. It is expected to represent other areas in Indonesia. This research provides an alternative framework of competitiveness analysis methods at the regional level. The concept of regional competitiveness can be a catalyst and enabler to the development of regional specialization and networking among regions in the era of economic globalization.
Parallel Flux Tensor Analysis for Efficient Moving Object Detection
2011-07-01
computing as well as parallelization to enable real time performance in analyzing complex video [3, 4 ]. There are a number of challenging computer vision... 4 . TITLE AND SUBTITLE Parallel Flux Tensor Analysis for Efficient Moving Object Detection 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT...We use the trace of the flux tensor matrix, referred to as Tr JF , that is defined below, Tr JF = ∫ Ω W (x− y)(I2xt(y) + I2yt(y) + I2tt(y))dy ( 4 ) as
Is competition needed for ecological character displacement? Does displacement decrease competition?
Abrams, Peter A; Cortez, Michael H
2015-12-01
Interspecific competition for resources is generally considered to be the selective force driving ecological character displacement, and displacement is assumed to reduce competition. Skeptics of the prevalence of character displacement often cite lack of evidence of competition. The present article uses a simple model to examine whether competition is needed for character displacement and whether displacement reduces competition. It treats systems with competing resources, and considers cases when only one consumer evolves. It quantifies competition using several different measures. The analysis shows that selection for divergence of consumers occurs regardless of the level of between-resource competition or whether the indirect interaction between the consumers is competition (-,-), mutualism (+,+), or contramensalism (+,-). Also, divergent evolution always decreases the equilibrium population size of the evolving consumer. Whether divergence of one consumer reduces or increases the impact of a subsequent perturbation of the other consumer depends on the parameters and the method chosen for measuring competition. Divergence in mutualistic interactions may reduce beneficial effects of subsequent increases in the other consumer's population. The evolutionary response is driven by an increase in the relative abundance of the resource the consumer catches more rapidly. Such an increase can occur under several types of interaction. © 2015 The Author(s). Evolution published by Wiley Periodicals, Inc. on behalf of The Society for the Study of Evolution.
Super and parallel computers and their impact on civil engineering
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kamat, M.P.
1986-01-01
This book presents the papers given at a conference on the use of supercomputers in civil engineering. Topics considered at the conference included solving nonlinear equations on a hypercube, a custom architectured parallel processing system, distributed data processing, algorithms, computer architecture, parallel processing, vector processing, computerized simulation, and cost benefit analysis.
Comparison between four dissimilar solar panel configurations
NASA Astrophysics Data System (ADS)
Suleiman, K.; Ali, U. A.; Yusuf, Ibrahim; Koko, A. D.; Bala, S. I.
2017-12-01
Several studies on photovoltaic systems focused on how it operates and energy required in operating it. Little attention is paid on its configurations, modeling of mean time to system failure, availability, cost benefit and comparisons of parallel and series-parallel designs. In this research work, four system configurations were studied. Configuration I consists of two sub-components arranged in parallel with 24 V each, configuration II consists of four sub-components arranged logically in parallel with 12 V each, configuration III consists of four sub-components arranged in series-parallel with 8 V each, and configuration IV has six sub-components with 6 V each arranged in series-parallel. Comparative analysis was made using Chapman Kolmogorov's method. The derivation for explicit expression of mean time to system failure, steady state availability and cost benefit analysis were performed, based on the comparison. Ranking method was used to determine the optimal configuration of the systems. The results of analytical and numerical solutions of system availability and mean time to system failure were determined and it was found that configuration I is the optimal configuration.
Liao, Chih-Hsien; Lu, Ning; Tang, Chao-Hsiun; Chang, Hui-Chih; Huang, Kuo-Cherh
2018-06-04
There is still significant uncertainty as to whether market competition raises or lowers clinical quality in publicly funded healthcare systems. We attempted to assess the effects of market competition on inpatient care quality of stroke patients in a retrospective study of the universal single-payer health insurance system in Taiwan. In this 11-year population-based study, we conducted a pooled time-series cross-sectional analysis with a fixed-effects model and the Hausman test approach by utilizing two nationwide datasets: the National Health Insurance Research Database and the National Hospital and Services Survey in Taiwan. Patients who were admitted to a hospital for ischemic or hemorrhagic stroke were enrolled. After excluding patients with a previous history of stroke and those with different types of stroke, 247 379 ischemic and 79 741 hemorrhagic stroke patients were included in our analysis. Four outcome indicators were applied: the in-hospital mortality rate, 30-day post-operative complication rate, 14-day re-admission rate and 30-day re-admission rate. Market competition exerted a negative or negligible effect on the medical care quality of stroke patients. Compared to hospitals located in a highly competitive market, in-hospital mortality rates for hemorrhagic stroke patients were significantly lower in moderately (β = -0.05, P < 0.01) and less competitive markets (β = -0.05, P < 0.01). Conversely, the impact of market competition on the quality of care of ischemic stroke patients was insignificant. Simply fostering market competition might not achieve the objective of improving the quality of health care. Other health policy actions need to be contemplated.
NASA Astrophysics Data System (ADS)
Grzeszczuk, A.; Kowalski, S.
2015-04-01
Compute Unified Device Architecture (CUDA) is a parallel computing platform developed by Nvidia for increase speed of graphics by usage of parallel mode for processes calculation. The success of this solution has opened technology General-Purpose Graphic Processor Units (GPGPUs) for applications not coupled with graphics. The GPGPUs system can be applying as effective tool for reducing huge number of data for pulse shape analysis measures, by on-line recalculation or by very quick system of compression. The simplified structure of CUDA system and model of programming based on example Nvidia GForce GTX580 card are presented by our poster contribution in stand-alone version and as ROOT application.
Parallel gene analysis with allele-specific padlock probes and tag microarrays
Banér, Johan; Isaksson, Anders; Waldenström, Erik; Jarvius, Jonas; Landegren, Ulf; Nilsson, Mats
2003-01-01
Parallel, highly specific analysis methods are required to take advantage of the extensive information about DNA sequence variation and of expressed sequences. We present a scalable laboratory technique suitable to analyze numerous target sequences in multiplexed assays. Sets of padlock probes were applied to analyze single nucleotide variation directly in total genomic DNA or cDNA for parallel genotyping or gene expression analysis. All reacted probes were then co-amplified and identified by hybridization to a standard tag oligonucleotide array. The technique was illustrated by analyzing normal and pathogenic variation within the Wilson disease-related ATP7B gene, both at the level of DNA and RNA, using allele-specific padlock probes. PMID:12930977
NASA Astrophysics Data System (ADS)
Qi, Zumin; Zhang, Jun; Xie, Yongjie; Zhang, Yi; Wang, Zehua; Zhou, Xiaofeng; Zhu, Jianhui; Zi, Yanyong; Zhong, Huihuang
2016-12-01
Asymmetric mode competitions are observed in the design of an X-band triaxial klystron amplifier with an asymmetric input cavity, and the generation mechanism of the asymmetric mode competition is analyzed in the paper. The results indicate that the asymmetric modes are excited in the buncher cavity. The asymmetric mode (coaxial TM612 mode) in the buncher cavity with the highest shunt impedance can start up first among the asymmetric modes with negative beam loading conductance. The coupling of the corresponding coaxial TE mode between the buncher and input cavity exacerbates the start oscillation of the asymmetric mode competition. The rationality of the analysis is demonstrated by cutting off the propagation of the corresponding coaxial TE modes between the buncher cavity and the input cavity, and the asymmetric mode competitions are thoroughly suppressed by specially designed reflectors and lossy material. In simulation, a microwave with a power of 1.28 GW and a frequency of 9.375 GHz is generated, and the extraction efficiency and the gain are 34.5% and 41.5 dB, respectively.
ERIC Educational Resources Information Center
Davies, Roy
1987-01-01
Discussion of the online information industry emphasizes the effects of non-price competition on its structure and the firms involved. Q-analysis is applied to data on medical databases and hosts, changes over a three-year period are identified, and an optimum structure for the industry based on economic theory is considered. (Author/LRW)
Combined heat and power systems: economic and policy barriers to growth.
Kalam, Adil; King, Abigail; Moret, Ellen; Weerasinghe, Upekha
2012-04-23
Combined Heat and Power (CHP) systems can provide a range of benefits to users with regards to efficiency, reliability, costs and environmental impact. Furthermore, increasing the amount of electricity generated by CHP systems in the United States has been identified as having significant potential for impressive economic and environmental outcomes on a national scale. Given the benefits from increasing the adoption of CHP technologies, there is value in improving our understanding of how desired increases in CHP adoption can be best achieved. These obstacles are currently understood to stem from regulatory as well as economic and technological barriers. In our research, we answer the following questions: Given the current policy and economic environment facing the CHP industry, what changes need to take place in this space in order for CHP systems to be competitive in the energy market? We focus our analysis primarily on Combined Heat and Power Systems that use natural gas turbines. Our analysis takes a two-pronged approach. We first conduct a statistical analysis of the impact of state policies on increases in electricity generated from CHP system. Second, we conduct a Cost-Benefit analysis to determine in which circumstances funding incentives are necessary to make CHP technologies cost-competitive. Our policy analysis shows that regulatory improvements do not explain the growth in adoption of CHP technologies but hold the potential to encourage increases in electricity generated from CHP system in small-scale applications. Our Cost-Benefit analysis shows that CHP systems are only cost competitive in large-scale applications and that funding incentives would be necessary to make CHP technology cost-competitive in small-scale applications. From the synthesis of these analyses we conclude that because large-scale applications of natural gas turbines are already cost-competitive, policy initiatives aimed at a CHP market dominated primarily by large-scale (and therefore already cost-competitive) systems have not been effectively directed. Our recommendation is that for CHP technologies using natural gas turbines, policy focuses should be on increasing CHP growth in small-scale systems. This result can be best achieved through redirection of state and federal incentives, research and development, adoption of smart grid technology, and outreach and education.
Competition of wormholes during the evolution of cave passages
NASA Astrophysics Data System (ADS)
Gabrovsek, Franci; Dreybrodt, Wolfgang
2017-04-01
Reactive fronts in two-dimensional plane parallel fractures, with constant head difference between input and output and with diffusion controlled first order reaction rates R = keff ṡ (Ceq - C), where keff = k ṡ (1 + ka/6D)-1, are instable to infinitesimal perturbations in fracture aperture width (1), causing spontaneous fingering of the reactive front resulting in the formation of wormholes. C is the actual concentration and Ceq the equilibrium concentration, a, is the actual aperture width of the fracture , and D the constant of molecular diffusion. Fingering happens also in plane-parallel rough fractures where it is triggered by the existence of statistically more favorable pathways. The same behavior is observed in rectangular two-dimensional networks of "one-dimensional" smooth fractures used in modeling the evolution of caves in soluble rock (2). Here the formation of caves can be regarded as the evolution of wormholes along the two-dimensional network. Once fingering has been triggered, either by instability or by roughness, many small fingers compete with each other and only a few survive. Here we investigate the competition between two seeded fingers in initially homogeneous fracture networks with identical aperture width of all fractures and also in inhomogeneous ones where the aperture widths are distributed log normally. In both cases our modeling reveals the rules of competition: By instability one of the fingers grows faster than its competitor therefore penetrating somewhat deeper. As a consequence the hydraulic head at its tip is higher than that close to the tip of the shorter finger. Therefore the fractures connecting the tip regions of both fingers carry flow from the deep finger to the tip region of its competitor. This cross-flow is replaced by increasing inflow of aggressive solution into the input of the winner, enhancing further dissolution and growth. On the other hand the cross-flow increases the head at the tip of the losing finger, and consequently decreases inflow of aggressive solution into it, thus inhibiting its further evolution. This mechanism supports further growth of the winner (wormhole) and stops the growth of its competitor. Similar competition happens in the case of several fingers competing. In any case we observe flow from the winning fingers to the loosing ones. The communication between the competitors is always established by cross flow between its tip regions. We will present various scenarios of wormhole formation, which demonstrate details of the competition of fingers arising from either the reactive instability or from the statistical distribution of fracture aperture widths. In conclusion we find that the initiation of wormholes results either from instability or from the statistical distribution of favorable pathways. Once growth of fingers has been initiated the evolution of the wormhole patterns becomes deterministic. (1) Szymczak, P., and A.J.C. Ladd (2011), The initial stages of cave formation: Beyond the one-dimensional paradigm, Earth Planet. Sci. Lett. 301, 424-432 (2) Dreybrodt, W., Gabrovšek, F., Romanov, D.(2005) Processes of Speleogenesis: A Modeling Approach. ZRC Publishing, Karst Research Institute at ZRC SAZU, Ljubljana
David B. South; James H. Miller
2007-01-01
Only a few growth and yield programs allow users to model the effects of hardwood competition on yields from pine plantations. Several of these programs were developed with the assumption that reducing hardwood competition would consistently produce a Type 2 growth response where pine volume gains increase over time. However, the actual response is not always a Type 2...
ERIC Educational Resources Information Center
Chen, Hsinchun; Martinez, Joanne; Kirchhoff, Amy; Ng, Tobun D.; Schatz, Bruce R.
1998-01-01
Grounded on object filtering, automatic indexing, and co-occurrence analysis, an experiment was performed using a parallel supercomputer to analyze over 400,000 abstracts in an INSPEC computer engineering collection. A user evaluation revealed that system-generated thesauri were better than the human-generated INSPEC subject thesaurus in concept…
USDA-ARS?s Scientific Manuscript database
A ‘dilute-and-shoot’ method for vitamin D and triacylglycerols is demonstrated that employed four mass spectrometers, operating in different ionization modes, for a ‘quadruple parallel mass spectrometry’ analysis, plus three other detectors, for seven detectors overall. Sets of five samples of diet...
Jeong, Irully; Park, Sunghee
2013-01-01
The purpose of this study was to examine differences in participation motivation and competition anxiety between Korean and non-Korean wheelchair tennis players and to identify relations between participation motivation and competition anxiety in each group. Sixty-six wheel-chair tennis players who participated in the 2013 Korea Open Wheel-chair Tennis Tournament in Seoul completed the Participation Motivation Survey and the Competitive State Anxiety Inventory II. Data were analyzed by a frequency analysis, descriptive statistics, Pearson’s correlation analysis, and independent samples t-test to identify participants’ demographic characteristics, differences in participation motivation, competition anxiety between Korean and non-Korean players, and correlations between participation motivation and competition anxiety in each group. Korean players reported significantly higher motivation in purification compared to non-Korean players, whereas non-Korean players reported significantly higher motivation in enjoyment. In addition, non-Korean players demonstrated higher cognitive anxiety and self-confidence compared to Korean players. Moreover, the physical anxiety of Korean players was negatively correlated with learning, health-fitness, and enjoyment motivation. On the other hand, only self-confidence was significantly related to learning motivation and enjoyment motivation in non-Korean players. Thus, the results presented herein provide evidence for the development of specialized counseling programs that consider the psychological characteristics of Korean wheelchair tennis players. PMID:24409429
NASA Astrophysics Data System (ADS)
Hou, Zhenlong; Huang, Danian
2017-09-01
In this paper, we make a study on the inversion of probability tomography (IPT) with gravity gradiometry data at first. The space resolution of the results is improved by multi-tensor joint inversion, depth weighting matrix and the other methods. Aiming at solving the problems brought by the big data in the exploration, we present the parallel algorithm and the performance analysis combining Compute Unified Device Architecture (CUDA) with Open Multi-Processing (OpenMP) based on Graphics Processing Unit (GPU) accelerating. In the test of the synthetic model and real data from Vinton Dome, we get the improved results. It is also proved that the improved inversion algorithm is effective and feasible. The performance of parallel algorithm we designed is better than the other ones with CUDA. The maximum speedup could be more than 200. In the performance analysis, multi-GPU speedup and multi-GPU efficiency are applied to analyze the scalability of the multi-GPU programs. The designed parallel algorithm is demonstrated to be able to process larger scale of data and the new analysis method is practical.
B-MIC: An Ultrafast Three-Level Parallel Sequence Aligner Using MIC.
Cui, Yingbo; Liao, Xiangke; Zhu, Xiaoqian; Wang, Bingqiang; Peng, Shaoliang
2016-03-01
Sequence alignment is the central process for sequence analysis, where mapping raw sequencing data to reference genome. The large amount of data generated by NGS is far beyond the process capabilities of existing alignment tools. Consequently, sequence alignment becomes the bottleneck of sequence analysis. Intensive computing power is required to address this challenge. Intel recently announced the MIC coprocessor, which can provide massive computing power. The Tianhe-2 is the world's fastest supercomputer now equipped with three MIC coprocessors each compute node. A key feature of sequence alignment is that different reads are independent. Considering this property, we proposed a MIC-oriented three-level parallelization strategy to speed up BWA, a widely used sequence alignment tool, and developed our ultrafast parallel sequence aligner: B-MIC. B-MIC contains three levels of parallelization: firstly, parallelization of data IO and reads alignment by a three-stage parallel pipeline; secondly, parallelization enabled by MIC coprocessor technology; thirdly, inter-node parallelization implemented by MPI. In this paper, we demonstrate that B-MIC outperforms BWA by a combination of those techniques using Inspur NF5280M server and the Tianhe-2 supercomputer. To the best of our knowledge, B-MIC is the first sequence alignment tool to run on Intel MIC and it can achieve more than fivefold speedup over the original BWA while maintaining the alignment precision.
Xyce Parallel Electronic Simulator Users' Guide Version 6.8
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keiter, Eric R.; Aadithya, Karthik Venkatraman; Mei, Ting
This manual describes the use of the Xyce Parallel Electronic Simulator. Xyce has been de- signed as a SPICE-compatible, high-performance analog circuit simulator, and has been written to support the simulation needs of the Sandia National Laboratories electrical designers. This development has focused on improving capability over the current state-of-the-art in the following areas: Capability to solve extremely large circuit problems by supporting large-scale parallel com- puting platforms (up to thousands of processors). This includes support for most popular parallel and serial computers. A differential-algebraic-equation (DAE) formulation, which better isolates the device model package from solver algorithms. This allows onemore » to develop new types of analysis without requiring the implementation of analysis-specific device models. Device models that are specifically tailored to meet Sandia's needs, including some radiation- aware devices (for Sandia users only). Object-oriented code design and implementation using modern coding practices. Xyce is a parallel code in the most general sense of the phrase$-$ a message passing parallel implementation $-$ which allows it to run efficiently a wide range of computing platforms. These include serial, shared-memory and distributed-memory parallel platforms. Attention has been paid to the specific nature of circuit-simulation problems to ensure that optimal parallel efficiency is achieved as the number of processors grows.« less
Co-gasification of solid waste and lignite - a case study for Western Macedonia.
Koukouzas, N; Katsiadakis, A; Karlopoulos, E; Kakaras, E
2008-01-01
Co-gasification of solid waste and coal is a very attractive and efficient way of generating power, but also an alternative way, apart from conventional technologies such as incineration and landfill, of treating waste materials. The technology of co-gasification can result in very clean power plants using a wide range of solid fuels but there are considerable economic and environmental challenges. The aim of this study is to present the available existing co-gasification techniques and projects for coal and solid wastes and to investigate the techno-economic feasibility, concerning the installation and operation of a 30MW(e) co-gasification power plant based on integrated gasification combined cycle (IGCC) technology, using lignite and refuse derived fuel (RDF), in the region of Western Macedonia prefecture (WMP), Greece. The gasification block was based on the British Gas-Lurgi (BGL) gasifier, while the gas clean-up block was based on cold gas purification. The competitive advantages of co-gasification systems can be defined both by the fuel feedstock and production flexibility but also by their environmentally sound operation. It also offers the benefit of commercial application of the process by-products, gasification slag and elemental sulphur. Co-gasification of coal and waste can be performed through parallel or direct gasification. Direct gasification constitutes a viable choice for installations with capacities of more than 350MW(e). Parallel gasification, without extensive treatment of produced gas, is recommended for gasifiers of small to medium size installed in regions where coal-fired power plants operate. The preliminary cost estimation indicated that the establishment of an IGCC RDF/lignite plant in the region of WMP is not profitable, due to high specific capital investment and in spite of the lower fuel supply cost. The technology of co-gasification is not mature enough and therefore high capital requirements are needed in order to set up a direct co-gasification plant. The cost of electricity estimated was not competitive, compared to the prices dominating the Greek electricity market and thus further economic evaluation is required. The project would be acceptable if modular construction of the unit was first adopted near operating power plants, based on parallel co-gasification, and gradually incorporating the remaining process steps (gas purification, power generation) with the aim of eventually establishing a true direct co-gasification plant.
Eckert, Paulo Roberto; Goltz, Evandro Claiton; Filho, Aly Ferreira Flores
2014-01-01
This work analyses the effects of segmentation followed by parallel magnetization of ring-shaped NdFeB permanent magnets used in slotless cylindrical linear actuators. The main purpose of the work is to evaluate the effects of that segmentation on the performance of the actuator and to present a general overview of the influence of parallel magnetization by varying the number of segments and comparing the results with ideal radially magnetized rings. The analysis is first performed by modelling mathematically the radial and circumferential components of magnetization for both radial and parallel magnetizations, followed by an analysis carried out by means of the 3D finite element method. Results obtained from the models are validated by measuring radial and tangential components of magnetic flux distribution in the air gap on a prototype which employs magnet rings with eight segments each with parallel magnetization. The axial force produced by the actuator was also measured and compared with the results obtained from numerical models. Although this analysis focused on a specific topology of cylindrical actuator, the observed effects on the topology could be extended to others in which surface-mounted permanent magnets are employed, including rotating electrical machines. PMID:25051032
Eckert, Paulo Roberto; Goltz, Evandro Claiton; Flores Filho, Aly Ferreira
2014-07-21
This work analyses the effects of segmentation followed by parallel magnetization of ring-shaped NdFeB permanent magnets used in slotless cylindrical linear actuators. The main purpose of the work is to evaluate the effects of that segmentation on the performance of the actuator and to present a general overview of the influence of parallel magnetization by varying the number of segments and comparing the results with ideal radially magnetized rings. The analysis is first performed by modelling mathematically the radial and circumferential components of magnetization for both radial and parallel magnetizations, followed by an analysis carried out by means of the 3D finite element method. Results obtained from the models are validated by measuring radial and tangential components of magnetic flux distribution in the air gap on a prototype which employs magnet rings with eight segments each with parallel magnetization. The axial force produced by the actuator was also measured and compared with the results obtained from numerical models. Although this analysis focused on a specific topology of cylindrical actuator, the observed effects on the topology could be extended to others in which surface-mounted permanent magnets are employed, including rotating electrical machines.
[CMACPAR an modified parallel neuro-controller for control processes].
Ramos, E; Surós, R
1999-01-01
CMACPAR is a Parallel Neurocontroller oriented to real time systems as for example Control Processes. Its characteristics are mainly a fast learning algorithm, a reduced number of calculations, great generalization capacity, local learning and intrinsic parallelism. This type of neurocontroller is used in real time applications required by refineries, hydroelectric centers, factories, etc. In this work we present the analysis and the parallel implementation of a modified scheme of the Cerebellar Model CMAC for the n-dimensional space projection using a mean granularity parallel neurocontroller. The proposed memory management allows for a significant memory reduction in training time and required memory size.
Improved obstacle avoidance and navigation for an autonomous ground vehicle
NASA Astrophysics Data System (ADS)
Giri, Binod; Cho, Hyunsu; Williams, Benjamin C.; Tann, Hokchhay; Shakya, Bicky; Bharam, Vishal; Ahlgren, David J.
2015-01-01
This paper presents improvements made to the intelligence algorithms employed on Q, an autonomous ground vehicle, for the 2014 Intelligent Ground Vehicle Competition (IGVC). In 2012, the IGVC committee combined the formerly separate autonomous and navigation challenges into a single AUT-NAV challenge. In this new challenge, the vehicle is required to navigate through a grassy obstacle course and stay within the course boundaries (a lane of two white painted lines) that guide it toward a given GPS waypoint. Once the vehicle reaches this waypoint, it enters an open course where it is required to navigate to another GPS waypoint while avoiding obstacles. After reaching the final waypoint, the vehicle is required to traverse another obstacle course before completing the run. Q uses modular parallel software architecture in which image processing, navigation, and sensor control algorithms run concurrently. A tuned navigation algorithm allows Q to smoothly maneuver through obstacle fields. For the 2014 competition, most revisions occurred in the vision system, which detects white lines and informs the navigation component. Barrel obstacles of various colors presented a new challenge for image processing: the previous color plane extraction algorithm would not suffice. To overcome this difficulty, laser range sensor data were overlaid on visual data. Q also participates in the Joint Architecture for Unmanned Systems (JAUS) challenge at IGVC. For 2014, significant updates were implemented: the JAUS component accepted a greater variety of messages and showed better compliance to the JAUS technical standard. With these improvements, Q secured second place in the JAUS competition.
Step back! Niche dynamics in cave-dwelling predators
NASA Astrophysics Data System (ADS)
Mammola, Stefano; Piano, Elena; Isaia, Marco
2016-08-01
The geometry of the Hutchinson's hypervolume derives from multiple selective pressures defined, on one hand, by the physiological tolerance of the species, and on the other, by intra- and interspecific competition. The quantification of these evolutionary forces is essential for the understanding of the coexistence of predators in light of competitive exclusion dynamics. We address this topic by investigating the ecological niche of two medium-sized troglophile spiders (Meta menardi and Pimoa graphitica). Over one year, we surveyed several populations in four subterranean sites in the Western Italian Alps, monitoring monthly their spatial and temporal dynamics and the associated physical and ecological variables. We assessed competition between the two species by means of multi regression techniques and by evaluating the intersection between their multidimensional hypervolumes. We detected a remarkable overlap between the microclimatic and trophic niche of M. menardi and P. graphitica, however, the former -being larger in size- resulted the best competitor in proximity of the cave entrance, causing the latter to readjust its spatial niche towards the inner part, where prey availability is scarcer ("step back effect"). In parallel to the slight variations in the subterranean microclimatic condition, the niche of the two species was also found to be seasonal dependent, varying over the year. With this work, we aim at providing new insights about the relationships among predators, demonstrating that energy-poor environments such as caves maintain the potential for diversification of predators via niche differentiation and serve as useful models for theoretical ecological studies.
Fully Parallel MHD Stability Analysis Tool
NASA Astrophysics Data System (ADS)
Svidzinski, Vladimir; Galkin, Sergei; Kim, Jin-Soo; Liu, Yueqiang
2014-10-01
Progress on full parallelization of the plasma stability code MARS will be reported. MARS calculates eigenmodes in 2D axisymmetric toroidal equilibria in MHD-kinetic plasma models. It is a powerful tool for studying MHD and MHD-kinetic instabilities and it is widely used by fusion community. Parallel version of MARS is intended for simulations on local parallel clusters. It will be an efficient tool for simulation of MHD instabilities with low, intermediate and high toroidal mode numbers within both fluid and kinetic plasma models, already implemented in MARS. Parallelization of the code includes parallelization of the construction of the matrix for the eigenvalue problem and parallelization of the inverse iterations algorithm, implemented in MARS for the solution of the formulated eigenvalue problem. Construction of the matrix is parallelized by distributing the load among processors assigned to different magnetic surfaces. Parallelization of the solution of the eigenvalue problem is made by repeating steps of the present MARS algorithm using parallel libraries and procedures. Initial results of the code parallelization will be reported. Work is supported by the U.S. DOE SBIR program.
Research in Parallel Algorithms and Software for Computational Aerosciences
NASA Technical Reports Server (NTRS)
Domel, Neal D.
1996-01-01
Phase I is complete for the development of a Computational Fluid Dynamics parallel code with automatic grid generation and adaptation for the Euler analysis of flow over complex geometries. SPLITFLOW, an unstructured Cartesian grid code developed at Lockheed Martin Tactical Aircraft Systems, has been modified for a distributed memory/massively parallel computing environment. The parallel code is operational on an SGI network, Cray J90 and C90 vector machines, SGI Power Challenge, and Cray T3D and IBM SP2 massively parallel machines. Parallel Virtual Machine (PVM) is the message passing protocol for portability to various architectures. A domain decomposition technique was developed which enforces dynamic load balancing to improve solution speed and memory requirements. A host/node algorithm distributes the tasks. The solver parallelizes very well, and scales with the number of processors. Partially parallelized and non-parallelized tasks consume most of the wall clock time in a very fine grain environment. Timing comparisons on a Cray C90 demonstrate that Parallel SPLITFLOW runs 2.4 times faster on 8 processors than its non-parallel counterpart autotasked over 8 processors.
Research in Parallel Algorithms and Software for Computational Aerosciences
NASA Technical Reports Server (NTRS)
Domel, Neal D.
1996-01-01
Phase 1 is complete for the development of a computational fluid dynamics CFD) parallel code with automatic grid generation and adaptation for the Euler analysis of flow over complex geometries. SPLITFLOW, an unstructured Cartesian grid code developed at Lockheed Martin Tactical Aircraft Systems, has been modified for a distributed memory/massively parallel computing environment. The parallel code is operational on an SGI network, Cray J90 and C90 vector machines, SGI Power Challenge, and Cray T3D and IBM SP2 massively parallel machines. Parallel Virtual Machine (PVM) is the message passing protocol for portability to various architectures. A domain decomposition technique was developed which enforces dynamic load balancing to improve solution speed and memory requirements. A host/node algorithm distributes the tasks. The solver parallelizes very well, and scales with the number of processors. Partially parallelized and non-parallelized tasks consume most of the wall clock time in a very fine grain environment. Timing comparisons on a Cray C90 demonstrate that Parallel SPLITFLOW runs 2.4 times faster on 8 processors than its non-parallel counterpart autotasked over 8 processors.
It's about time : investing in transportation to keep Texas economically competitive.
DOT National Transportation Integrated Search
2011-03-01
This current report, It's About Time: Investing in Transportation to Keep Texas : Economically Competitive, updates the February 2009 report by providing : an enhanced analysis of the current state of the Texas transportation system, : determining th...
Parallel line analysis: multifunctional software for the biomedical sciences
NASA Technical Reports Server (NTRS)
Swank, P. R.; Lewis, M. L.; Damron, K. L.; Morrison, D. R.
1990-01-01
An easy to use, interactive FORTRAN program for analyzing the results of parallel line assays is described. The program is menu driven and consists of five major components: data entry, data editing, manual analysis, manual plotting, and automatic analysis and plotting. Data can be entered from the terminal or from previously created data files. The data editing portion of the program is used to inspect and modify data and to statistically identify outliers. The manual analysis component is used to test the assumptions necessary for parallel line assays using analysis of covariance techniques and to determine potency ratios with confidence limits. The manual plotting component provides a graphic display of the data on the terminal screen or on a standard line printer. The automatic portion runs through multiple analyses without operator input. Data may be saved in a special file to expedite input at a future time.
Dynamic competition in pharmaceuticals. Patent expiry, generic penetration, and industry structure.
Magazzini, Laura; Pammolli, Fabio; Riccaboni, Massimo
2004-06-01
This paper investigates patterns of industrial dynamics and competition in the pharmaceutical industry, with particular reference to the consequences of patent expiry in different countries. We focus on the competition at the level of single chemical entities, distinguishing between original brands and generic products. Quarterly data, spanning from July 1987 to December 1998, on sales of pharmaceutical products in four countries (USA, UK, Germany, and France) constitute the basis of our analysis. All the products containing major molecules whose patent expiration date lies between 1986 and 1996 are included in our sample. We show how diffusion of generics is linked to the characteristics of the market and investigate how price dynamics of original products are affected by generic competition. Our empirical investigation shows that the dynamics of drug prices and the competition by generic drugs vary significantly across countries. This heterogeneity notwithstanding, a clear distinction seems to emerge. On the one hand, systems that rely on market-based competition in pharmaceuticals promote a clear distinction between firms that act as innovators and firms that act as imitators after patent expiry. Here, original products enjoy premium prices and exclusivity profits under patent protection, and face fierce price competition after patent expiry. On the other hand, in systems that rely on administered prices, penetration by generic drugs tends to be rather limited. Its descriptive and preliminary nature notwithstanding, our analysis seems to have relevant implications at different levels of generality, especially for Europe.
CFD Analysis and Design Optimization Using Parallel Computers
NASA Technical Reports Server (NTRS)
Martinelli, Luigi; Alonso, Juan Jose; Jameson, Antony; Reuther, James
1997-01-01
A versatile and efficient multi-block method is presented for the simulation of both steady and unsteady flow, as well as aerodynamic design optimization of complete aircraft configurations. The compressible Euler and Reynolds Averaged Navier-Stokes (RANS) equations are discretized using a high resolution scheme on body-fitted structured meshes. An efficient multigrid implicit scheme is implemented for time-accurate flow calculations. Optimum aerodynamic shape design is achieved at very low cost using an adjoint formulation. The method is implemented on parallel computing systems using the MPI message passing interface standard to ensure portability. The results demonstrate that, by combining highly efficient algorithms with parallel computing, it is possible to perform detailed steady and unsteady analysis as well as automatic design for complex configurations using the present generation of parallel computers.
Vectorization and parallelization of the finite strip method for dynamic Mindlin plate problems
NASA Technical Reports Server (NTRS)
Chen, Hsin-Chu; He, Ai-Fang
1993-01-01
The finite strip method is a semi-analytical finite element process which allows for a discrete analysis of certain types of physical problems by discretizing the domain of the problem into finite strips. This method decomposes a single large problem into m smaller independent subproblems when m harmonic functions are employed, thus yielding natural parallelism at a very high level. In this paper we address vectorization and parallelization strategies for the dynamic analysis of simply-supported Mindlin plate bending problems and show how to prevent potential conflicts in memory access during the assemblage process. The vector and parallel implementations of this method and the performance results of a test problem under scalar, vector, and vector-concurrent execution modes on the Alliant FX/80 are also presented.
Module Six: Parallel Circuits; Basic Electricity and Electronics Individualized Learning System.
ERIC Educational Resources Information Center
Bureau of Naval Personnel, Washington, DC.
In this module the student will learn the rules that govern the characteristics of parallel circuits; the relationships between voltage, current, resistance and power; and the results of common troubles in parallel circuits. The module is divided into four lessons: rules of voltage and current, rules for resistance and power, variational analysis,…
Lardi, Martina; de Campos, Samanta Bolzan; Purtschert, Gabriela; Eberl, Leo; Pessi, Gabriella
2017-01-01
Members of the genus Burkholderia (β-proteobacteria) have only recently been shown to be able to establish a nitrogen-fixing symbiosis with several legumes, which is why they are also referred to as β-rhizobia. Therefore, very little is known about the competitiveness of these species to nodulate different legume host plants. In this study, we tested the competitiveness of several Burkholderia type strains (B. diazotrophica, B. mimosarum, B. phymatum, B. sabiae, B. symbiotica and B. tuberum) to nodulate four legumes (Phaseolus vulgaris, Macroptilium atropurpureum, Vigna unguiculata and Mimosa pudica) under our closely defined growth conditions. The assessment of nodule occupancy of these species on different legume host plants revealed that B. phymatum was the most competitive strain in the three papilionoid legumes (bean, cowpea and siratro), while B. mimosarum outcompeted the other strains in mimosa. The analysis of phenotypes known to play a role in nodulation competitiveness (motility, exopolysaccharide production) and additional in vitro competition assays among β-rhizobial strains suggested that B. phymatum has the potential to be a very competitive legume symbiont. PMID:28861050
Xirasagar, Sudha; Lin, Herng-Ching
2004-01-01
Objective To test the hypotheses that: (1) average adjusted costs per discharge are higher in high-competition relative to low-competition markets, and (2) increased competition is associated with cost convergence between public and for-profit (FP) hospitals for case payment diagnoses, but not for cost-plus reimbursed diagnoses. Data Sources Taiwan's National Health Insurance database; 325,851 inpatient claims for cesarean section, vaginal delivery, prostatectomy, and thyroidectomy (all case payment), and bronchial asthma and cholelithiasis (both cost-based payment). Study Design Retrospective population-based, cross-sectional study. Data Analysis Diagnosis-wise regression analyses were done to explore associations between cost per discharge and hospital ownership under high and low competition, adjusted for clinical severity and institutional characteristics. Principal Findings Adjusted costs per discharge are higher for all diagnoses in high-competition markets. For case payment diagnoses, the magnitudes of adjusted cost differences between public and FP hospitals are lower under high competition relative to low competition. This is not so for the cost-based diagnoses. Conclusions We find that the empirical evidence supports both our hypotheses. PMID:15544646
Spatial competition dynamics between reef corals under ocean acidification
Horwitz, Rael; Hoogenboom, Mia O.; Fine, Maoz
2017-01-01
Climate change, including ocean acidification (OA), represents a major threat to coral-reef ecosystems. Although previous experiments have shown that OA can negatively affect the fitness of reef corals, these have not included the long-term effects of competition for space on coral growth rates. Our multispecies year-long study subjected reef-building corals from the Gulf of Aqaba (Red Sea) to competitive interactions under present-day ocean pH (pH 8.1) and predicted end-of-century ocean pH (pH 7.6). Results showed coral growth is significantly impeded by OA under intraspecific competition for five out of six study species. Reduced growth from OA, however, is negligible when growth is already suppressed in the presence of interspecific competition. Using a spatial competition model, our analysis indicates shifts in the competitive hierarchy and a decrease in overall coral cover under lowered pH. Collectively, our case study demonstrates how modified competitive performance under increasing OA will in all likelihood change the composition, structure and functionality of reef coral communities. PMID:28067281
Ali, Ashehad A.; Medlyn, Belinda E.; Aubier, Thomas G.; ...
2015-10-06
Differential species responses to atmospheric CO 2 concentration (C a) could lead to quantitative changes in competition among species and community composition, with flow-on effects for ecosystem function. However, there has been little theoretical analysis of how elevated C a (eC a) will affect plant competition, or how composition of plant communities might change. Such theoretical analysis is needed for developing testable hypotheses to frame experimental research. Here, we investigated theoretically how plant competition might change under eC a by implementing two alternative competition theories, resource use theory and resource capture theory, in a plant carbon and nitrogen cycling model.more » The model makes several novel predictions for the impact of eC a on plant community composition. Using resource use theory, the model predicts that eC a is unlikely to change species dominance in competition, but is likely to increase coexistence among species. Using resource capture theory, the model predicts that eC a may increase community evenness. Collectively, both theories suggest that eC a will favor coexistence and hence that species diversity should increase with eC a. Our theoretical analysis leads to a novel hypothesis for the impact of eC a on plant community composition. In this study, the hypothesis has potential to help guide the design and interpretation of eC a experiments.« less
NASA Astrophysics Data System (ADS)
Rahimi, Mohammad; Kim, Taeyoung; Gorski, Christopher A.; Logan, Bruce E.
2018-01-01
Thermally regenerative ammonia batteries (TRABs) have shown great promise as a method to convert low-grade waste heat into electrical power, with power densities an order of magnitude higher than other approaches. However, previous TRABs based on copper electrodes suffered from unbalanced anode dissolution and cathode deposition rates during discharging cycles, limiting practical applications. To produce a TRAB with stable and reversible electrode reactions over many cycles, inert carbon electrodes were used with silver salts. In continuous flow tests, power production was stable over 100 discharging cycles, demonstrating excellent reversibility. Power densities were 23 W m-2-electrode area in batch tests, which was 64% higher than that produced in parallel tests using copper electrodes, and 30 W m-2 (net energy density of 490 Wh m-3-anolyte) in continuous flow tests. While this battery requires the use a precious metal, an initial economic analysis of the system showed that the cost of the materials relative to energy production was 220 per MWh, which is competitive with energy production from other non-fossil fuel sources. A substantial reduction in costs could be obtained by developing less expensive anion exchange membranes.
Revisiting the Al/Al 2O 3 Interface: Coherent Interfaces and Misfit Accommodation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pilania, Ghanshyam; Thijsse, Barend J.; Hoagland, Richard G.
We report the coherent and semi-coherent Al/α-Al 2O 3 interfaces using molecular dynamics simulations with a mixed, metallic-ionic atomistic model. For the coherent interfaces, both Al-terminated and O-terminated nonstoichiometric interfaces have been studied and their relative stability has been established. To understand the misfit accommodation at the semi-coherent interface, a 1-dimensional (1D) misfit dislocation model and a 2-dimensional (2D) dislocation network model have been studied. For the latter case, our analysis reveals an interface dislocation structure with a network of three sets of parallel dislocations, each with pure-edge character, giving rise to a pattern of coherent and stacking-fault-like regions atmore » the interface. Structural relaxation at elevated temperatures leads to a further change of the dislocation pattern, which can be understood in terms of a competition between the stacking fault energy and the dislocation interaction energy at the interface. In conclusion, our results are expected to serve as an input for the subsequent dislocation dynamics models to understand and predict the macroscopic mechanical behavior of Al/α-Al 2O 3 composite heterostructures.« less
Revisiting the Al/Al 2O 3 Interface: Coherent Interfaces and Misfit Accommodation
Pilania, Ghanshyam; Thijsse, Barend J.; Hoagland, Richard G.; ...
2014-03-27
We report the coherent and semi-coherent Al/α-Al 2O 3 interfaces using molecular dynamics simulations with a mixed, metallic-ionic atomistic model. For the coherent interfaces, both Al-terminated and O-terminated nonstoichiometric interfaces have been studied and their relative stability has been established. To understand the misfit accommodation at the semi-coherent interface, a 1-dimensional (1D) misfit dislocation model and a 2-dimensional (2D) dislocation network model have been studied. For the latter case, our analysis reveals an interface dislocation structure with a network of three sets of parallel dislocations, each with pure-edge character, giving rise to a pattern of coherent and stacking-fault-like regions atmore » the interface. Structural relaxation at elevated temperatures leads to a further change of the dislocation pattern, which can be understood in terms of a competition between the stacking fault energy and the dislocation interaction energy at the interface. In conclusion, our results are expected to serve as an input for the subsequent dislocation dynamics models to understand and predict the macroscopic mechanical behavior of Al/α-Al 2O 3 composite heterostructures.« less
Life-cycle assessment of diesel, natural gas and hydrogen fuel cell bus transportation systems
NASA Astrophysics Data System (ADS)
Ally, Jamie; Pryor, Trevor
The Sustainable Transport Energy Programme (STEP) is an initiative of the Government of Western Australia, to explore hydrogen fuel cell technology as an alternative to the existing diesel and natural gas public transit infrastructure in Perth. This project includes three buses manufactured by DaimlerChrysler with Ballard fuel cell power sources operating in regular service alongside the existing natural gas and diesel bus fleets. The life-cycle assessment (LCA) of the fuel cell bus trial in Perth determines the overall environmental footprint and energy demand by studying all phases of the complete transportation system, including the hydrogen infrastructure, bus manufacturing, operation, and end-of-life disposal. The LCAs of the existing diesel and natural gas transportation systems are developed in parallel. The findings show that the trial is competitive with the diesel and natural gas bus systems in terms of global warming potential and eutrophication. Emissions that contribute to acidification and photochemical ozone are greater for the fuel cell buses. Scenario analysis quantifies the improvements that can be expected in future generations of fuel cell vehicles and shows that a reduction of greater than 50% is achievable in the greenhouse gas, photochemical ozone creation and primary energy demand impact categories.
TAVR vs SAVR: Rising Expectations and Changing Indications for Surgery in Response to PARTNER II.
Spadaccio, Cristiano; Nappi, Francesco; Sablayrolles, Jean-Louis; Sutherland, Fraser W H
2017-01-01
Despite the criticisms and concerns raised on the data published in the PARTNER II trial and related analyses, we are undeniably witnessing a revolution in the management of aortic valve disease, in which conventional full sternotomy surgical aortic valve replacement (SAVR), with all related complications and clinical burden, will soon become a nonviable option. Several of the findings described in the PARTNER II trial, although considerable as points of incongruence and study biases in comparison with SAVR, could be taken as lessons to found a new course in SAVR and redesign the respective roles of surgery and interventional procedures in aortic disease. In particular, the results of these trials can actually be considered as a stimulus to invest more effort to improve the current surgical practice that should embrace alternative solutions and least invasive approaches to provide a competitive advantage over percutaneous procedures. An analysis of these points in light of the more recent findings on transcatheter valve durability, thrombosis, and postprocedural complications is provided. Considerations on the parallel progress of SAVR and on the need for a behavioral change in the surgical community are discussed. Copyright © 2017 Elsevier Inc. All rights reserved.
Identification of Chemical-Genetic Interactions via Parallel Analysis of Barcoded Yeast Strains.
Suresh, Sundari; Schlecht, Ulrich; Xu, Weihong; Miranda, Molly; Davis, Ronald W; Nislow, Corey; Giaever, Guri; St Onge, Robert P
2016-09-01
The Yeast Knockout Collection is a complete set of gene deletion strains for the budding yeast, Saccharomyces cerevisiae In each strain, one of approximately 6000 open-reading frames is replaced with a dominant selectable marker flanked by two DNA barcodes. These barcodes, which are unique to each gene, allow the growth of thousands of strains to be individually measured from a single pooled culture. The collection, and other resources that followed, has ushered in a new era in chemical biology, enabling unbiased and systematic identification of chemical-genetic interactions (CGIs) with remarkable ease. CGIs link bioactive compounds to biological processes, and hence can reveal the mechanism of action of growth-inhibitory compounds in vivo, including those of antifungal, antibiotic, and anticancer drugs. The chemogenomic profiling method described here measures the sensitivity induced in yeast heterozygous and homozygous deletion strains in the presence of a chemical inhibitor of growth (termed haploinsufficiency profiling and homozygous profiling, respectively, or HIPHOP). The protocol is both scalable and amenable to automation. After competitive growth of yeast knockout collection cultures, with and without chemical inhibitors, CGIs can be identified and quantified using either array- or sequencing-based approaches as described here. © 2016 Cold Spring Harbor Laboratory Press.
TECA: A Parallel Toolkit for Extreme Climate Analysis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Prabhat, Mr; Ruebel, Oliver; Byna, Surendra
2012-03-12
We present TECA, a parallel toolkit for detecting extreme events in large climate datasets. Modern climate datasets expose parallelism across a number of dimensions: spatial locations, timesteps and ensemble members. We design TECA to exploit these modes of parallelism and demonstrate a prototype implementation for detecting and tracking three classes of extreme events: tropical cyclones, extra-tropical cyclones and atmospheric rivers. We process a modern TB-sized CAM5 simulation dataset with TECA, and demonstrate good runtime performance for the three case studies.
Lekberg, Ylva; Bever, James D; Bunn, Rebecca A; Callaway, Ragan M; Hart, Miranda M; Kivlin, Stephanie N; Klironomos, John; Larkin, Beau G; Maron, John L; Reinhart, Kurt O; Remke, Michael; van der Putten, Wim H
2018-06-12
Plants interact simultaneously with each other and with soil biota, yet the relative importance of competition vs. plant-soil feedback (PSF) on plant performance is poorly understood. Using a meta-analysis of 38 published studies and 150 plant species, we show that effects of interspecific competition (either growing plants with a competitor or singly, or comparing inter- vs. intraspecific competition) and PSF (comparing home vs. away soil, live vs. sterile soil, or control vs. fungicide-treated soil) depended on treatments but were predominantly negative, broadly comparable in magnitude, and additive or synergistic. Stronger competitors experienced more negative PSF than weaker competitors when controlling for density (inter- to intraspecific competition), suggesting that PSF could prevent competitive dominance and promote coexistence. When competition was measured against plants growing singly, the strength of competition overwhelmed PSF, indicating that the relative importance of PSF may depend not only on neighbour identity but also density. We evaluate how competition and PSFs might interact across resource gradients; PSF will likely strengthen competitive interactions in high resource environments and enhance facilitative interactions in low-resource environments. Finally, we provide a framework for filling key knowledge gaps and advancing our understanding of how these biotic interactions influence community structure. © 2018 John Wiley & Sons Ltd/CNRS.
Everhart, Damian; Neff, Donna; Al-Amin, Mona; Nogle, June; Weech-Maldonado, Robert
2013-01-01
Background Hospitals facing financial uncertainty have sought to reduce nurse staffing as a way to increase profitability. However, nurse staffing has been found to be important in terms of quality of patient care and nursing related outcomes. Nurse staffing can provide a competitive advantage to hospitals and as a result better financial performance, particularly in more competitive markets Purpose In this study we build on the Resource-Based View of the Firm to determine the effect of nurse staffing on total profit margin in more competitive and less competitive hospital markets in Florida. Methodology/Approach By combining a Florida statewide nursing survey with the American Hospital Association Annual Survey and the Area Resource File, three separate multivariate linear regression models were conducted to determine the effect of nurse staffing on financial performance while accounting for market competitiveness. The analysis was limited to acute care hospitals. Findings Nurse staffing levels had a positive association with financial performance (β=3.3; p=0.02) in competitive hospital markets, but no significant association was found in less competitive hospital markets. Practice Implications Hospitals in more competitive hospital markets should reconsider reducing nursing staff, as these cost cutting measures may be inefficient and negatively affect financial performance. PMID:22543824
Peric, M; Cavar, M; Zenic, N; Sekulic, D; Sajber, D
2014-02-01
This study examined the applicability of sport-specific fitness tests (SSTs), anthropometrics, and respiratory parameters in predicting competitive results among pubescent synchronized swimmers. A total of 25 synchronized swimmers (16-17 years; 166.2 ± 5.4 cm; and 58.4 ± 4.3 kg) volunteered for this study. The independent variables were body mass, body height, Body Mass Index (BMI), body fat percentage (BF%), lean body mass percentage, respiratory variables, and four SSTs (two specific power tests plus one aerobic- and one anaerobic-endurance test). The dependent variable was competitive achievement in the solo figure competition. The reliability analyses, Pearson's correlation coefficient and forward stepwise regression were calculated. The SSTs were reliable for testing fitness status among pubescent synchronized swimmers. The forward stepwise regression retained two SSTs, BF% and forced vital capacity (FVC, relative for age and stature) in a set of predictors of competitive achievement. Significant Beta coefficients are found for aerobic-endurance, SST and FVC. The sport-specific measure of aerobic endurance and FVC appropriately predicted competitive achievement with regard to the figures used in the competition when competitive results (the dependent variable) were obtained. Athletes and coaches should be aware of the probable negative influence of very low body fat levels on competitive achievement.
Plant interspecies competition for sunlight: a mathematical model of canopy partitioning.
Nevai, Andrew L; Vance, Richard R
2007-07-01
We examine the influence of canopy partitioning on the outcome of competition between two plant species that interact only by mutually shading each other. This analysis is based on a Kolmogorov-type canopy partitioning model for plant species with clonal growth form and fixed vertical leaf profiles (Vance and Nevai in J. Theor. Biol., 2007, to appear). We show that canopy partitioning is necessary for the stable coexistence of the two competing plant species. We also use implicit methods to show that, under certain conditions, the species' nullclines can intersect at most once. We use nullcline endpoint analysis to show that when the nullclines do intersect, and in such a way that they cross, then the resulting equilibrium point is always stable. We also construct surfaces that divide parameter space into regions within which the various outcomes of competition occur, and then study parameter dependence in the locations of these surfaces. The analysis presented here and in a companion paper (Nevai and Vance, The role of leaf height in plant competition for sunlight: analysis of a canopy partitioning model, in review) together shows that canopy partitioning is both necessary and, under appropriate parameter values, sufficient for the stable coexistence of two hypothetical plant species whose structure and growth are described by our model.
Kinematic Analysis and Performance Evaluation of Novel PRS Parallel Mechanism
NASA Astrophysics Data System (ADS)
Balaji, K.; Khan, B. Shahul Hamid
2018-02-01
In this paper, a 3 DoF (Degree of Freedom) novel PRS (Prismatic-Revolute- Spherical) type parallel mechanisms has been designed and presented. The combination of striaght and arc type linkages for 3 DOF parallel mechanism is introduced for the first time. The performances of the mechanisms are evaluated based on the indices such as Minimum Singular Value (MSV), Condition Number (CN), Local Conditioning Index (LCI), Kinematic Configuration Index (KCI) and Global Conditioning Index (GCI). The overall reachable workspace of all mechanisms are presented. The kinematic measure, dexterity measure and workspace analysis for all the mechanism have been evaluated and compared.
Applications and accuracy of the parallel diagonal dominant algorithm
NASA Technical Reports Server (NTRS)
Sun, Xian-He
1993-01-01
The Parallel Diagonal Dominant (PDD) algorithm is a highly efficient, ideally scalable tridiagonal solver. In this paper, a detailed study of the PDD algorithm is given. First the PDD algorithm is introduced. Then the algorithm is extended to solve periodic tridiagonal systems. A variant, the reduced PDD algorithm, is also proposed. Accuracy analysis is provided for a class of tridiagonal systems, the symmetric, and anti-symmetric Toeplitz tridiagonal systems. Implementation results show that the analysis gives a good bound on the relative error, and the algorithm is a good candidate for the emerging massively parallel machines.
ERIC Educational Resources Information Center
Hwang, Ming-Yueh; Hong, Jon-Chao; Cheng, Hao-Yueh; Peng, Yu-Chi; Wu, Nien-Chen
2013-01-01
Do girls have more competition anxiety and exogenous cognitive load than equally able boys during the playing of stressful competitive on-line games? This question led to the adoption of a technology acceptance model to compare the influence factors of competitors in sequential and synchronous games. Confirmatory factor analysis of the data on 220…
Fluid and Electrolyte Needs for Training, Competition, and Recovery
2011-01-01
begin both training and competition in a state of fluid deficit. Analysis of samples collected from elite football ( soccer ) players before training...surprisingly, samples collected from players before a competitive game revealed that 8 of the 20 outfield players had a urine osmolality in excess of...2007) reported that basketball players attempted fewer shots and were less able to make shots linked with movement (e.g. lay-up) when dehydration had
Nonlinear Markov Control Processes and Games
2012-11-15
the analysis of a new class of stochastic games , nonlinear Markov games , as they arise as a ( competitive ) controlled version of nonlinear Markov... competitive interests) a nonlinear Markov game that we are investigating. I 0. :::tUt::JJt:.l.. I I t:t11VI;:, nonlinear Markov game , nonlinear Markov...corresponding stochastic game Γ+(T, h). In a slightly different setting one can assume that changes in a competitive control process occur as a
ESTIMATION OF WATER DEMANDS USING DEFICIT ANALYSIS
Competition for water among governmental entities with common river systems has become increasingly fierce. The competition will no doubt become even more fierce as populations continue to grow and become increasingly dispersed. One of the major issues involved in water resource ...
FPGA-Based Filterbank Implementation for Parallel Digital Signal Processing
NASA Technical Reports Server (NTRS)
Berner, Stephan; DeLeon, Phillip
1999-01-01
One approach to parallel digital signal processing decomposes a high bandwidth signal into multiple lower bandwidth (rate) signals by an analysis bank. After processing, the subband signals are recombined into a fullband output signal by a synthesis bank. This paper describes an implementation of the analysis and synthesis banks using (Field Programmable Gate Arrays) FPGAs.
Parallel Analysis with Unidimensional Binary Data
ERIC Educational Resources Information Center
Weng, Li-Jen; Cheng, Chung-Ping
2005-01-01
The present simulation investigated the performance of parallel analysis for unidimensional binary data. Single-factor models with 8 and 20 indicators were examined, and sample size (50, 100, 200, 500, and 1,000), factor loading (.45, .70, and .90), response ratio on two categories (50/50, 60/40, 70/30, 80/20, and 90/10), and types of correlation…
ERIC Educational Resources Information Center
Gow, David W., Jr.; Keller, Corey J.; Eskandar, Emad; Meng, Nate; Cash, Sydney S.
2009-01-01
In this work, we apply Granger causality analysis to high spatiotemporal resolution intracranial EEG (iEEG) data to examine how different components of the left perisylvian language network interact during spoken language perception. The specific focus is on the characterization of serial versus parallel processing dependencies in the dominant…
An Analysis of the Role of ATC in the AILS Concept
NASA Technical Reports Server (NTRS)
Waller, Marvin C.; Doyle, Thomas M.; McGee, Frank G.
2000-01-01
Airborne information for lateral spacing (AILS) is a concept for making approaches to closely spaced parallel runways in instrument meteorological conditions (IMC). Under the concept, each equipped aircraft will assume responsibility for accurately managing its flight path along the approach course and maintaining separation from aircraft on the parallel approach. This document presents the results of an analysis of the AILS concept from an Air Traffic Control (ATC) perspective. The process has been examined in a step by step manner to determine ATC system support necessary to safely conduct closely spaced parallel approaches using the AILS concept. The analysis resulted in recognizing a number of issues related to integrating the process into the airspace system and proposes operating procedures.
The coevolution of ova defensiveness with sperm competitiveness in house mice.
Firman, Renée C; Gomendio, Montserrat; Roldan, Eduardo R S; Simmons, Leigh W
2014-04-01
Theoretical models have suggested that sperm competition can lead to increased ova resistance to fertilization. While there is some comparative evidence that this might be true, there is no experimental evidence to show that ova defensiveness evolves in response to sperm competition. We performed a series of in vitro fertilization assays to gauge the fertilizability of ova produced by female house mice from experimental populations that evolved either with or without sperm competition. Our analysis revealed that after 24 generations of experimental evolution, females that evolved under a polygamous regime produced more defensive ova than females that evolved under a monogamous regime. We therefore provide the first direct line of evidence that sperm competition can generate sexual conflict at the gametic level and lead to asymmetries in fertilization rates among populations. Our results show that females respond to sperm competition via fertilization barriers that have the potential to mediate sperm entry.
The Physiological Demands of Table Tennis: A Review
Kondrič, Miran; Zagatto, Alessandro Moura; Sekulić, Damir
2013-01-01
Although table tennis has a tradition lasting more than 100 years, relatively little is known about players’ physiological requirements – especially during competition. In this review we discuss research studies that have led to our current understanding of how the body functions during table tennis training and competition and how this is altered by training. Match and practice analysis of the table tennis game indicates that during intense practice and competition it is predominantly the anaerobic alactic system that is called into play, while the endurance system is relied on to recovery the anaerobic stores used during such effort. It is thus important for coaches to keep in mind that, while the anaerobic alactic system is the most energetic system used during periods of exertion in a table tennis game, a strong capacity for endurance is what helps a player recover quicker for the following match and the next day of competition. This paper provides a review of specific studies that relate to competitive table tennis, and highlights the need for training and research programs tailored to table tennis. Key Points Match and practice analysis of the table tennis game indicates that during intense practice and competition it is predominantly the anaerobic alactic system that is called into play. The endurance system is relied on to recovery the anaerobic stores used during hard practice and competition effort. It is important for coaches to keep in mind that, while the anaerobic alactic system is the most energetic system used during periods of exertion in a table tennis game, a strong capacity for endurance is what helps a player recover quicker for the following match and the next day of competition. PMID:24149139
Parallel Hybrid Gas-Electric Geared Turbofan Engine Conceptual Design and Benefits Analysis
NASA Technical Reports Server (NTRS)
Lents, Charles; Hardin, Larry; Rheaume, Jonathan; Kohlman, Lee
2016-01-01
The conceptual design of a parallel gas-electric hybrid propulsion system for a conventional single aisle twin engine tube and wing vehicle has been developed. The study baseline vehicle and engine technology are discussed, followed by results of the hybrid propulsion system sizing and performance analysis. The weights analysis for the electric energy storage & conversion system and thermal management system is described. Finally, the potential system benefits are assessed.
Neural representation of objects in space: a dual coding account.
Humphreys, G W
1998-01-01
I present evidence on the nature of object coding in the brain and discuss the implications of this coding for models of visual selective attention. Neuropsychological studies of task-based constraints on: (i) visual neglect; and (ii) reading and counting, reveal the existence of parallel forms of spatial representation for objects: within-object representations, where elements are coded as parts of objects, and between-object representations, where elements are coded as independent objects. Aside from these spatial codes for objects, however, the coding of visual space is limited. We are extremely poor at remembering small spatial displacements across eye movements, indicating (at best) impoverished coding of spatial position per se. Also, effects of element separation on spatial extinction can be eliminated by filling the space with an occluding object, indicating that spatial effects on visual selection are moderated by object coding. Overall, there are separate limits on visual processing reflecting: (i) the competition to code parts within objects; (ii) the small number of independent objects that can be coded in parallel; and (iii) task-based selection of whether within- or between-object codes determine behaviour. Between-object coding may be linked to the dorsal visual system while parallel coding of parts within objects takes place in the ventral system, although there may additionally be some dorsal involvement either when attention must be shifted within objects or when explicit spatial coding of parts is necessary for object identification. PMID:9770227
Talanow, Tobias; Kasparbauer, Anna-Maria; Steffens, Maria; Meyhöfer, Inga; Weber, Bernd; Smyrnis, Nikolaos; Ettinger, Ulrich
2016-08-01
The antisaccade task is a prominent tool to investigate the response inhibition component of cognitive control. Recent theoretical accounts explain performance in terms of parallel programming of exogenous and endogenous saccades, linked to the horse race metaphor. Previous studies have tested the hypothesis of competing saccade signals at the behavioral level by selectively slowing the programming of endogenous or exogenous processes e.g. by manipulating the probability of antisaccades in an experimental block. To gain a better understanding of inhibitory control processes in parallel saccade programming, we analyzed task-related eye movements and blood oxygenation level dependent (BOLD) responses obtained using functional magnetic resonance imaging (fMRI) at 3T from 16 healthy participants in a mixed antisaccade and prosaccade task. The frequency of antisaccade trials was manipulated across blocks of high (75%) and low (25%) antisaccade frequency. In blocks with high antisaccade frequency, antisaccade latencies were shorter and error rates lower whilst prosaccade latencies were longer and error rates were higher. At the level of BOLD, activations in the task-related saccade network (left inferior parietal lobe, right inferior parietal sulcus, left precentral gyrus reaching into left middle frontal gyrus and inferior frontal junction) and deactivations in components of the default mode network (bilateral temporal cortex, ventromedial prefrontal cortex) compensated increased cognitive control demands. These findings illustrate context dependent mechanisms underlying the coordination of competing decision signals in volitional gaze control. Copyright © 2016 Elsevier Inc. All rights reserved.
Preconditioned conjugate gradient methods for the compressible Navier-Stokes equations
NASA Technical Reports Server (NTRS)
Venkatakrishnan, V.
1990-01-01
The compressible Navier-Stokes equations are solved for a variety of two-dimensional inviscid and viscous problems by preconditioned conjugate gradient-like algorithms. Roe's flux difference splitting technique is used to discretize the inviscid fluxes. The viscous terms are discretized by using central differences. An algebraic turbulence model is also incorporated. The system of linear equations which arises out of the linearization of a fully implicit scheme is solved iteratively by the well known methods of GMRES (Generalized Minimum Residual technique) and Chebyschev iteration. Incomplete LU factorization and block diagonal factorization are used as preconditioners. The resulting algorithm is competitive with the best current schemes, but has wide applications in parallel computing and unstructured mesh computations.
Design and implementation of online automatic judging system
NASA Astrophysics Data System (ADS)
Liang, Haohui; Chen, Chaojie; Zhong, Xiuyu; Chen, Yuefeng
2017-06-01
For lower efficiency and poorer reliability in programming training and competition by currently artificial judgment, design an Online Automatic Judging (referred to as OAJ) System. The OAJ system including the sandbox judging side and Web side, realizes functions of automatically compiling and running the tested codes, and generating evaluation scores and corresponding reports. To prevent malicious codes from damaging system, the OAJ system utilizes sandbox, ensuring the safety of the system. The OAJ system uses thread pools to achieve parallel test, and adopt database optimization mechanism, such as horizontal split table, to improve the system performance and resources utilization rate. The test results show that the system has high performance, high reliability, high stability and excellent extensibility.
Preliminary results of the large experimental wind turbine phase of the national wind energy program
NASA Technical Reports Server (NTRS)
Thomas, R. L.; Sholes, J. E.
1975-01-01
A major phase of the wind energy program is the development of reliable wind turbines for supplying cost-competitive electrical energy. This paper discusses the preliminary results of two projects in this phase of the program. First an experimental 100 kW wind turbine design and its status are reviewed. Also discussed are the results of two parallel design studies for determining the configurations and power levels for wind turbines with minimum energy costs. These studies show wind energy costs of 7 to 1.5 c/kWH for wind turbines produced in quantities of 100 to 1000 a year and located at sites having average winds of 12 to 18 mph.
Phase-space dynamics of runaway electrons in magnetic fields
Guo, Zehua; McDevitt, Christopher Joseph; Tang, Xian-Zhu
2017-02-16
Dynamics of runaway electrons in magnetic fields are governed by the competition of three dominant physics: parallel electric field acceleration, Coulomb collision, and synchrotron radiation. Examination of the energy and pitch-angle flows reveals that the presence of local vortex structure and global circulation is crucial to the saturation of primary runaway electrons. Models for the vortex structure, which has an O-point to X-point connection, and the bump of runaway electron distribution in energy space have been developed and compared against the simulation data. Lastly, identification of these velocity-space structures opens a new venue to re-examine the conventional understanding of runawaymore » electron dynamics in magnetic fields.« less
Optical resonators and neural networks
NASA Astrophysics Data System (ADS)
Anderson, Dana Z.
1986-08-01
It may be possible to implement neural network models using continuous field optical architectures. These devices offer the inherent parallelism of propagating waves and an information density in principle dictated by the wavelength of light and the quality of the bulk optical elements. Few components are needed to construct a relatively large equivalent network. Various associative memories based on optical resonators have been demonstrated in the literature, a ring resonator design is discussed in detail here. Information is stored in a holographic medium and recalled through a competitive processes in the gain medium supplying energy to the ring rsonator. The resonator memory is the first realized example of a neural network function implemented with this kind of architecture.
Physical and Physiological Profiles of Brazilian Jiu-Jitsu Athletes: a Systematic Review.
Andreato, Leonardo Vidal; Lara, Francisco Javier Díaz; Andrade, Alexandro; Branco, Braulio Henrique Magnani
2017-12-01
Brazilian jiu-jitsu is a grappling combat sport that has intermittency as its core element; in other words, actions of high, moderate and low intensity are interspersed during matches, requiring a high level of conditioning to support optimal levels of performance for the total match time. The athletes perform from four to six matches during a day of competition, and this number may increase if the open-class competition, which is held parallel to the competition by weight class, is considered. This systematic review examined the physical and physiological profiles of Brazilian jiu-jitsu athletes. Only scientific researches dealing with the major fitness components of Brazilian jiu-jitsu athletes (i.e. body composition and somatotype, aerobic and anaerobic profiles, muscular strength and power) and using accepted methods that provided relevant practical applications for a Brazilian jiu-jitsu athlete's fitness training and/or performance were included in the current review. A computer literature search was carried out of the PubMed, ISI Web of Knowledge, SportDiscus and Scopus databases (up to January 2016). The database research generated 205 articles. After the application of inclusion and exclusion criteria, 58 studies were included for the present systematic review. A total of 1496 subjects were involved in all the selected investigations. Body fat is generally low for these athletes and the mesomorphic component is predominant. The different studies showed VO 2max values between 42 and 52 mL/kg/min, and it seems that aerobic fitness does not discriminate among Brazilian jiu-jitsu athletes of different competitive levels. There is a lack of scientific studies that have investigated anaerobic responses both in lower and upper limbs. Maximal dynamic, isometric and endurance strength can be associated with sporting success in Brazilian jiu-jitsu athletes. Although decisive actions during Brazilian jiu-jitsu matches are mainly dependent on muscular power, more specific studies are necessary to describe it. Studies involving the female sex should be conducted. In addition, further research is needed to analyse whether there are differences between sex, belt ranks and competitive level, and among the different weight categories for different variables.
Augustine, David J; Springer, Tim L
2013-06-01
Potential competition between native and domestic herbivores is a major consideration influencing the management and conservation of native herbivores in rangeland ecosystems. In grasslands of the North American Great Plains, black-tailed prairie dogs (Cynomys ludovicianus) are widely viewed as competitors with cattle but are also important for biodiversity conservation due to their role in creating habitat for other native species. We examined spatiotemporal variation in prairie dog effects on growing-season forage quality and quantity using measurements from three colony complexes in Colorado and South Dakota and from a previous study of a fourth complex in Montana. At two complexes experiencing below-average precipitation, forage availability both on and off colonies was so low (12-54 g/m2) that daily forage intake rates of cattle were likely constrained by instantaneous intake rates and daily foraging time. Under these dry conditions, prairie dogs (1) substantially reduced forage availability, thus further limiting cattle daily intake rates, and (2) had either no or a small positive effect on forage digestibility. Under such conditions, prairie dogs are likely to compete with cattle in direct proportion to their abundance. For two complexes experiencing above-average precipitation, forage quantity on and off colonies (77-208 g/m2) was sufficient for daily forage intake of cattle to be limited by digestion rather than instantaneous forage intake. At one complex where prairie dogs enhanced forage digestibility and [N] while having no effect on forage quantity, prairie dogs are predicted to facilitate cattle mass gains regardless of prairie dog abundance. At the second complex where prairie dogs enhanced digestibility and [N] but reduced forage quantity, effects on cattle can vary from competition to facilitation depending on prairie dog abundance. Our findings show that the high spatiotemporal variation in vegetation dynamics characteristic of semiarid grasslands is paralleled by variability in the magnitude of competition between native and domestic grazers. Competitive interactions evident during dry periods may be partially or wholly offset by facilitation during periods when forage digestibility is enhanced and forage quantity does not limit the daily intake rate of cattle.
Observations of large parallel electric fields in the auroral ionosphere
NASA Technical Reports Server (NTRS)
Mozer, F. S.
1976-01-01
Rocket borne measurements employing a double probe technique were used to gather evidence for the existence of electric fields in the auroral ionosphere having components parallel to the magnetic field direction. An analysis of possible experimental errors leads to the conclusion that no known uncertainties can account for the roughly 10 mV/m parallel electric fields that are observed.
An Analysis of Techno-Economic Requirements for MOSAIC CPV Systems to Achieve Cost Competitiveness
DOE Office of Scientific and Technical Information (OSTI.GOV)
Horowitz, Kelsey A; Cunningham, David W.; Zahler, James
A comprehensive bottom-up cost model has been developed by NREL for ARPAE's MOSAIC micro-concentrator PV program. It will calculate LCOE for MOSAIC technologies and assess their cost competitiveness compared to traditional flat-plate systems.
Cloud parallel processing of tandem mass spectrometry based proteomics data.
Mohammed, Yassene; Mostovenko, Ekaterina; Henneman, Alex A; Marissen, Rob J; Deelder, André M; Palmblad, Magnus
2012-10-05
Data analysis in mass spectrometry based proteomics struggles to keep pace with the advances in instrumentation and the increasing rate of data acquisition. Analyzing this data involves multiple steps requiring diverse software, using different algorithms and data formats. Speed and performance of the mass spectral search engines are continuously improving, although not necessarily as needed to face the challenges of acquired big data. Improving and parallelizing the search algorithms is one possibility; data decomposition presents another, simpler strategy for introducing parallelism. We describe a general method for parallelizing identification of tandem mass spectra using data decomposition that keeps the search engine intact and wraps the parallelization around it. We introduce two algorithms for decomposing mzXML files and recomposing resulting pepXML files. This makes the approach applicable to different search engines, including those relying on sequence databases and those searching spectral libraries. We use cloud computing to deliver the computational power and scientific workflow engines to interface and automate the different processing steps. We show how to leverage these technologies to achieve faster data analysis in proteomics and present three scientific workflows for parallel database as well as spectral library search using our data decomposition programs, X!Tandem and SpectraST.
A visual parallel-BCI speller based on the time-frequency coding strategy.
Xu, Minpeng; Chen, Long; Zhang, Lixin; Qi, Hongzhi; Ma, Lan; Tang, Jiabei; Wan, Baikun; Ming, Dong
2014-04-01
Spelling is one of the most important issues in brain-computer interface (BCI) research. This paper is to develop a visual parallel-BCI speller system based on the time-frequency coding strategy in which the sub-speller switching among four simultaneously presented sub-spellers and the character selection are identified in a parallel mode. The parallel-BCI speller was constituted by four independent P300+SSVEP-B (P300 plus SSVEP blocking) spellers with different flicker frequencies, thereby all characters had a specific time-frequency code. To verify its effectiveness, 11 subjects were involved in the offline and online spellings. A classification strategy was designed to recognize the target character through jointly using the canonical correlation analysis and stepwise linear discriminant analysis. Online spellings showed that the proposed parallel-BCI speller had a high performance, reaching the highest information transfer rate of 67.4 bit min(-1), with an average of 54.0 bit min(-1) and 43.0 bit min(-1) in the three rounds and five rounds, respectively. The results indicated that the proposed parallel-BCI could be effectively controlled by users with attention shifting fluently among the sub-spellers, and highly improved the BCI spelling performance.
Xyce™ Parallel Electronic Simulator Users' Guide, Version 6.5.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keiter, Eric R.; Aadithya, Karthik V.; Mei, Ting
This manual describes the use of the Xyce Parallel Electronic Simulator. Xyce has been designed as a SPICE-compatible, high-performance analog circuit simulator, and has been written to support the simulation needs of the Sandia National Laboratories electrical designers. This development has focused on improving capability over the current state-of-the-art in the following areas: Capability to solve extremely large circuit problems by supporting large-scale parallel computing platforms (up to thousands of processors). This includes support for most popular parallel and serial computers. A differential-algebraic-equation (DAE) formulation, which better isolates the device model package from solver algorithms. This allows one to developmore » new types of analysis without requiring the implementation of analysis-specific device models. Device models that are specifically tailored to meet Sandia's needs, including some radiation- aware devices (for Sandia users only). Object-oriented code design and implementation using modern coding practices. Xyce is a parallel code in the most general sense of the phrase -- a message passing parallel implementation -- which allows it to run efficiently a wide range of computing platforms. These include serial, shared-memory and distributed-memory parallel platforms. Attention has been paid to the specific nature of circuit-simulation problems to ensure that optimal parallel efficiency is achieved as the number of processors grows. The information herein is subject to change without notice. Copyright © 2002-2016 Sandia Corporation. All rights reserved.« less
GPU accelerated dynamic functional connectivity analysis for functional MRI data.
Akgün, Devrim; Sakoğlu, Ünal; Esquivel, Johnny; Adinoff, Bryon; Mete, Mutlu
2015-07-01
Recent advances in multi-core processors and graphics card based computational technologies have paved the way for an improved and dynamic utilization of parallel computing techniques. Numerous applications have been implemented for the acceleration of computationally-intensive problems in various computational science fields including bioinformatics, in which big data problems are prevalent. In neuroimaging, dynamic functional connectivity (DFC) analysis is a computationally demanding method used to investigate dynamic functional interactions among different brain regions or networks identified with functional magnetic resonance imaging (fMRI) data. In this study, we implemented and analyzed a parallel DFC algorithm based on thread-based and block-based approaches. The thread-based approach was designed to parallelize DFC computations and was implemented in both Open Multi-Processing (OpenMP) and Compute Unified Device Architecture (CUDA) programming platforms. Another approach developed in this study to better utilize CUDA architecture is the block-based approach, where parallelization involves smaller parts of fMRI time-courses obtained by sliding-windows. Experimental results showed that the proposed parallel design solutions enabled by the GPUs significantly reduce the computation time for DFC analysis. Multicore implementation using OpenMP on 8-core processor provides up to 7.7× speed-up. GPU implementation using CUDA yielded substantial accelerations ranging from 18.5× to 157× speed-up once thread-based and block-based approaches were combined in the analysis. Proposed parallel programming solutions showed that multi-core processor and CUDA-supported GPU implementations accelerated the DFC analyses significantly. Developed algorithms make the DFC analyses more practical for multi-subject studies with more dynamic analyses. Copyright © 2015 Elsevier Ltd. All rights reserved.
Portrait, France R M; van der Galiën, Onno; Van den Berg, Bernard
2016-04-01
The Dutch healthcare system is in transition towards managed competition. In theory, a system of managed competition involves incentives for quality and efficiency of provided care. This is mainly because health insurers contract on behalf of their clients with healthcare providers on, potentially, quality and costs. The paper develops a strategy to comprehensively analyse available multidimensional data on quality and costs to assess and report on the relative performance of healthcare providers within managed competition. We had access to individual information on 2409 clients of 19 Dutch diabetes care groups on a broad range of (outcome and process related) quality and cost indicators. We carried out a cost-consequences analysis and corrected for differences in case mix to reduce incentives for risk selection by healthcare providers. There is substantial heterogeneity between diabetes care groups' performances as measured using multidimensional indicators on quality and costs. Better quality diabetes care can be achieved with lower or higher costs. Routine monitoring using multidimensional data on quality and costs merged at the individual level would allow a systematic and comprehensive analysis of healthcare providers' performances within managed competition. Copyright © 2015 John Wiley & Sons, Ltd.
NASA Astrophysics Data System (ADS)
Aditi, Bunga
2017-12-01
This research is done to know and analyzing the effect of attribute, halal certification product, and product innovation on the competitiveness of Micro Small and Medium Business in Medan, knowing and analyzing the effect of product attribute, halal certification, and product innovation to consumer buying surge. The type of research used is explanatory research with quantitative approach. The population in this study is the community as consumers who are in the area of Medan province of North Sumatera. Total sample of 150 people. Sampling method which use an accidental sampling is the technique of determining samples by chance, example: consumers whomeets with researcher coincidentally can be sampled if the consumer is appropriate or suitable as a source of data. This research uses the method of Structural Equation Modeling analysis. The mainting of this research is showed that product attributes, halal certification, and product innovation had a positive and significant impact on competitive advantage which impact on consumer buy-back (surge) interest. The advantage competitive has affects consumer buying surge interest positively. Keywords: Product attributes, halal certification, product innovation, competitive advantage, consumer buying interest
Application of GIS in exploring spatial dimensions of Efficiency in Competitiveness of Regions
NASA Astrophysics Data System (ADS)
Rahmat, Shahid; Sen, Joy
2017-04-01
Infrastructure is an important component in building competitiveness of a region. Present global scenario of economic slowdown that is led by slump in demand of goods and services and decreasing capacity of government institutions in investing public infrastructure. Strategy of augmenting competitiveness of a region can be built around improving efficient distribution of public infrastructure in the region. This efficiency in the distribution of infrastructure will reduce the burden of government institution and improve the relative output of the region in relative lesser investment. A rigorous literature study followed by an expert opinion survey (RIDIT scores) reveals that Railway, Road, ICTs and Electricity infrastructure is very crucial for better competitiveness of a region. Discussion with Experts in ICTs, Railways and Electricity sectors were conducted to find the issues, hurdles and possible solution for the development of these sectors. In an underdeveloped country like India, there is a large constrain of financial resources, for investment in infrastructure sector. Judicious planning for allocation of resources for infrastructure provisions becomes very important for efficient and sustainable development. Data Envelopment Analysis (DEA) is the mathematical programming optimization tool that measure technical efficiency of the multiple-input and/or multiple-output case by constructing a relative technical efficiency score. This paper tries to utilize DEA to identify the efficiency at which present level of selected components of Infrastructure (Railway, Road, ICTs and Electricity) is utilized in order to build competitiveness of the region. This paper tries to identify a spatial pattern of efficiency of Infrastructure with the help of spatial auto-correlation and Hot-spot analysis in Arc GIS. This analysis leads to policy implications for efficient allocation of financial resources for the provision of infrastructure in the region and building a prerequisite to boost an efficient Regional Competitiveness.
Analysis of multigrid methods on massively parallel computers: Architectural implications
NASA Technical Reports Server (NTRS)
Matheson, Lesley R.; Tarjan, Robert E.
1993-01-01
We study the potential performance of multigrid algorithms running on massively parallel computers with the intent of discovering whether presently envisioned machines will provide an efficient platform for such algorithms. We consider the domain parallel version of the standard V cycle algorithm on model problems, discretized using finite difference techniques in two and three dimensions on block structured grids of size 10(exp 6) and 10(exp 9), respectively. Our models of parallel computation were developed to reflect the computing characteristics of the current generation of massively parallel multicomputers. These models are based on an interconnection network of 256 to 16,384 message passing, 'workstation size' processors executing in an SPMD mode. The first model accomplishes interprocessor communications through a multistage permutation network. The communication cost is a logarithmic function which is similar to the costs in a variety of different topologies. The second model allows single stage communication costs only. Both models were designed with information provided by machine developers and utilize implementation derived parameters. With the medium grain parallelism of the current generation and the high fixed cost of an interprocessor communication, our analysis suggests an efficient implementation requires the machine to support the efficient transmission of long messages, (up to 1000 words) or the high initiation cost of a communication must be significantly reduced through an alternative optimization technique. Furthermore, with variable length message capability, our analysis suggests the low diameter multistage networks provide little or no advantage over a simple single stage communications network.
Stability of tapered and parallel-walled dental implants: A systematic review and meta-analysis.
Atieh, Momen A; Alsabeeha, Nabeel; Duncan, Warwick J
2018-05-15
Clinical trials have suggested that dental implants with a tapered configuration have improved stability at placement, allowing immediate placement and/or loading. The aim of this systematic review and meta-analysis was to evaluate the implant stability of tapered dental implants compared to standard parallel-walled dental implants. Applying the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement, randomized controlled trials (RCTs) were searched for in electronic databases and complemented by hand searching. The risk of bias was assessed using the Cochrane Collaboration's Risk of Bias tool and data were analyzed using statistical software. A total of 1199 studies were identified, of which, five trials were included with 336 dental implants in 303 participants. Overall meta-analysis showed that tapered dental implants had higher implant stability values than parallel-walled dental implants at insertion and 8 weeks but the difference was not statistically significant. Tapered dental implants had significantly less marginal bone loss compared to parallel-walled dental implants. No significant differences in implant failure rate were found between tapered and parallel-walled dental implants. There is limited evidence to demonstrate the effectiveness of tapered dental implants in achieving greater implant stability compared to parallel-walled dental implants. Superior short-term results in maintaining peri-implant marginal bone with tapered dental implants are possible. Further properly designed RCTs are required to endorse the supposed advantages of tapered dental implants in immediate loading protocol and other complex clinical scenarios. © 2018 Wiley Periodicals, Inc.
Competitive employment training for mentally retarded adults: the supported work model.
Krauss, M W; MacEachron, A E
1982-05-01
The supported work model designed to train mentally retarded persons for competitive employment, was initiated as a pilot program in 1979. The placement rate was 50 percent. In order to investigate the predictors of placement, we conducted an empirical analysis using the theory of work adjustment perspective. Results indicated that the participant's work behavior and job skills, ability to meet the requirements of the jobs, and employment reinforcements were predictors of competitive placement.
Fully Parallel MHD Stability Analysis Tool
NASA Astrophysics Data System (ADS)
Svidzinski, Vladimir; Galkin, Sergei; Kim, Jin-Soo; Liu, Yueqiang
2015-11-01
Progress on full parallelization of the plasma stability code MARS will be reported. MARS calculates eigenmodes in 2D axisymmetric toroidal equilibria in MHD-kinetic plasma models. It is a powerful tool for studying MHD and MHD-kinetic instabilities and it is widely used by fusion community. Parallel version of MARS is intended for simulations on local parallel clusters. It will be an efficient tool for simulation of MHD instabilities with low, intermediate and high toroidal mode numbers within both fluid and kinetic plasma models, already implemented in MARS. Parallelization of the code includes parallelization of the construction of the matrix for the eigenvalue problem and parallelization of the inverse iterations algorithm, implemented in MARS for the solution of the formulated eigenvalue problem. Construction of the matrix is parallelized by distributing the load among processors assigned to different magnetic surfaces. Parallelization of the solution of the eigenvalue problem is made by repeating steps of the present MARS algorithm using parallel libraries and procedures. Results of MARS parallelization and of the development of a new fix boundary equilibrium code adapted for MARS input will be reported. Work is supported by the U.S. DOE SBIR program.
Computer-Aided Parallelizer and Optimizer
NASA Technical Reports Server (NTRS)
Jin, Haoqiang
2011-01-01
The Computer-Aided Parallelizer and Optimizer (CAPO) automates the insertion of compiler directives (see figure) to facilitate parallel processing on Shared Memory Parallel (SMP) machines. While CAPO currently is integrated seamlessly into CAPTools (developed at the University of Greenwich, now marketed as ParaWise), CAPO was independently developed at Ames Research Center as one of the components for the Legacy Code Modernization (LCM) project. The current version takes serial FORTRAN programs, performs interprocedural data dependence analysis, and generates OpenMP directives. Due to the widely supported OpenMP standard, the generated OpenMP codes have the potential to run on a wide range of SMP machines. CAPO relies on accurate interprocedural data dependence information currently provided by CAPTools. Compiler directives are generated through identification of parallel loops in the outermost level, construction of parallel regions around parallel loops and optimization of parallel regions, and insertion of directives with automatic identification of private, reduction, induction, and shared variables. Attempts also have been made to identify potential pipeline parallelism (implemented with point-to-point synchronization). Although directives are generated automatically, user interaction with the tool is still important for producing good parallel codes. A comprehensive graphical user interface is included for users to interact with the parallelization process.
Competition in the German pharmacy market: an empirical analysis
2013-01-01
Background Pharmaceutical products are an important component of expenditure on public health insurance in the Federal Republic of Germany. For years, German policy makers have regulated public pharmacies in order to limit the increase in costs. One reform has followed another, main objective being to increase competition in the pharmacy market. It is generally assumed that an increase in competition would reduce healthcare costs. However, there is a lack of empirical proof of a stronger orientation of German public pharmacies towards competition thus far. Methods This paper analyses the self-perceptions of owners of German public pharmacies and their orientation towards competition in the pharmacy markets. It is based on a cross-sectional survey (N = 289) and distinguishes between successful and less successful pharmacies, the location of the pharmacies (e.g. West German States and East German States) and the gender of the pharmacy owner. The data are analysed descriptively by survey items and employing bivariate and structural equation modelling. Results The analysis reveals that the majority of owners of public pharmacies in Germany do not currently perceive very strong competitive pressure in the market. However, the innovativeness of the pharmacist is confirmed as most relevant for net revenue development and the profit margin. Some differences occur between regions, e.g. public pharmacies in West Germany have a significantly higher profit margin. Conclusions This study provides evidence that the German healthcare reforms aimed at increasing the competition between public pharmacies in Germany have not been completely successful. Many owners of public pharmacies disregard instruments of active customer-orientated management (such as customer loyalty or an offensive position and economies of scale), which could give them a competitive advantage. However, it is clear that those pharmacists who strive for systematic and innovative management and adopt an offensive and competitive stance are quite successful. Thus, pharmacists should change their attitude and develop a more professional business model. PMID:24112461
Competition in the German pharmacy market: an empirical analysis.
Heinsohn, Jörg G; Flessa, Steffen
2013-10-10
Pharmaceutical products are an important component of expenditure on public health insurance in the Federal Republic of Germany. For years, German policy makers have regulated public pharmacies in order to limit the increase in costs. One reform has followed another, main objective being to increase competition in the pharmacy market. It is generally assumed that an increase in competition would reduce healthcare costs. However, there is a lack of empirical proof of a stronger orientation of German public pharmacies towards competition thus far. This paper analyses the self-perceptions of owners of German public pharmacies and their orientation towards competition in the pharmacy markets. It is based on a cross-sectional survey (N = 289) and distinguishes between successful and less successful pharmacies, the location of the pharmacies (e.g. West German States and East German States) and the gender of the pharmacy owner. The data are analysed descriptively by survey items and employing bivariate and structural equation modelling. The analysis reveals that the majority of owners of public pharmacies in Germany do not currently perceive very strong competitive pressure in the market. However, the innovativeness of the pharmacist is confirmed as most relevant for net revenue development and the profit margin. Some differences occur between regions, e.g. public pharmacies in West Germany have a significantly higher profit margin. This study provides evidence that the German healthcare reforms aimed at increasing the competition between public pharmacies in Germany have not been completely successful. Many owners of public pharmacies disregard instruments of active customer-orientated management (such as customer loyalty or an offensive position and economies of scale), which could give them a competitive advantage. However, it is clear that those pharmacists who strive for systematic and innovative management and adopt an offensive and competitive stance are quite successful. Thus, pharmacists should change their attitude and develop a more professional business model.
Agirdas, Cagdas; Krebs, Robert J; Yano, Masato
2018-01-08
One goal of the Affordable Care Act is to increase insurance coverage by improving competition and lowering premiums. To facilitate this goal, the federal government enacted online marketplaces in the 395 rating areas spanning 34 states that chose not to establish their own state-run marketplaces. Few multivariate regression studies analyzing the effects of competition on premiums suffer from endogeneity, due to simultaneity and omitted variable biases. However, United Healthcare's decision to enter these marketplaces in 2015 provides the researcher with an opportunity to address this endogeneity problem. Exploiting the variation caused by United Healthcare's entry decision as an instrument for competition, we study the impact of competition on premiums during the first 2 years of these marketplaces. Combining panel data from five different sources and controlling for 12 variables, we find that one more insurer in a rating area leads to a 6.97% reduction in the second-lowest-priced silver plan premium, which is larger than the estimated effects in existing literature. Furthermore, we run a threshold analysis and find that competition's effects on premiums become statistically insignificant if there are four or more insurers in a rating area. These findings are robust to alternative measures of premiums, inclusion of a non-linear term in the regression models and a county-level analysis.
CanSat Competition: Contributing to the Development of NASA's Vision for Robotic Space Exploration
NASA Technical Reports Server (NTRS)
Berman, Joshua; Berman, Timothy; Billheimer, Thomas; Biclmer. Elizabeth; Hood, Stuart; Neas, Charles
2007-01-01
CanSat is an international student design-build-launch competition organized by the American Astronautical Society (AAS) and American Institute of Aeronautics and Astronautics (AIAA). The competition is also sponsored by the Naval Research Laboratory (NRL) and the National Aeronautics and Space Administration (NASA). The CanSat competition is designed for college, university and high school students wanting to participate in an applicable space-related competition. The objective of the CanSat competition is to complete space exploration missions by designing a specific system for a small sounding rocket payload which will follow and perform to a specific set of rules and guidelines for each year's competition. The competition encompasses a complete life-cycle of one year which includes all phases of design, integration, testing, judging and competition. The mission guidelines are based from space exploration missions and include bonus requirement options which teams may choose to participate in. The fundamental goal of the competition is to educate future engineers and scientists. This is accomplished by students applying systems engineering practices to a development project that incorporates an end-to-end life cycle, from requirements analysis, through preliminary design, integration and testing, an actual flight of the CanSat, and concluding with a post-mission debrief. This is done specifically with space related missions to bring a unique aspect of engineering and design to the competition. The competition has been progressing since its creation in 2005. The competition was originally meant to purely convey the engineering and design process to its participants, but through many experiences the competition has also undergone a learning experience with respect to systems engineering process and design. According
Does Intellectual Property Restrict Output? An Analysis of Pharmaceutical Markets*
Lakdawalla, Darius; Philipson, Tomas
2013-01-01
Standard normative analysis of intellectual property focuses on the balance between incentives for research and the static welfare costs of reduced price-competition from monopoly. However, static welfare loss from patents is not universal. While patents restrict price competition, they may also provide static welfare benefits by improving incentives for marketing, which is a form of non-price competition. We show theoretically how stronger marketing incentives mitigate, and can even offset, the static costs of monopoly pricing. Empirical analysis in the pharmaceutical industry context suggests that, in the short-run, patent expirations reduce consumer welfare as a result of decreased marketing effort. In the long-run, patent expirations do benefit consumers, but by 30% less than would be implied by the reduction in price alone. The social value of monopoly marketing to consumers alone is roughly on par with its costs to firms. PMID:25221349
Does Intellectual Property Restrict Output? An Analysis of Pharmaceutical Markets.
Lakdawalla, Darius; Philipson, Tomas
2012-02-01
Standard normative analysis of intellectual property focuses on the balance between incentives for research and the static welfare costs of reduced price-competition from monopoly. However, static welfare loss from patents is not universal. While patents restrict price competition, they may also provide static welfare benefits by improving incentives for marketing, which is a form of non -price competition. We show theoretically how stronger marketing incentives mitigate, and can even offset, the static costs of monopoly pricing. Empirical analysis in the pharmaceutical industry context suggests that, in the short-run, patent expirations reduce consumer welfare as a result of decreased marketing effort. In the long-run, patent expirations do benefit consumers, but by 30% less than would be implied by the reduction in price alone. The social value of monopoly marketing to consumers alone is roughly on par with its costs to firms.
NASA Astrophysics Data System (ADS)
Hou, Rui; Wu, Jiawen; Du, Helen S.
2017-03-01
To explain the competition phenomenon and results between QQ and MSN (China) in the Chinese instant messaging software market, this paper developed a new population competition model based on customer social network. The simulation results show that the firm whose product with greater network externality effect will gain more market share than its rival when the same marketing strategy is used. The firm with the advantage of time, derived from the initial scale effect will become more competitive than its rival when facing a group of common penguin customers within a social network, verifying the winner-take-all phenomenon in this case.
Preliminary Assessment of Spatial Competition in the Market for E85
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bentley Clinton
The Preliminary Assessment of Spatial Competition in the Market for E85 presentation and supplementary report from the U.S. Department of Energy’s National Renewable Energy Laboratory examine how the spacing of E85 fueling stations impacts E85 retail pricing. The analysis finds an inverse correlation between station density and E85 prices, with local competition putting downward pressure on E85 prices. A gas station with E85 whose nearest competitor is within a 0.5 mile radius is associated with a lower E85 price per gallon than an otherwise identical station with E85 whose nearest competitor is farther away. The analysis also finds a highermore » level of correlation between E85 and both E10 and wholesale gasoline prices than with ethanol costs. This indicates that E85 may, in fact, be priced with respect to its substitute fuel, and not based on the cost of its inputs. These findings help identify key trends and barriers in E85 markets and highlight data gaps that, if addressed, could help enable competitive E85 markets. The analysis was released in February 2017 and uses national and Minnesota-specific price data.« less
Preliminary Assessment of Spatial Competition in the Market for E85: Presentation Supplement
DOE Office of Scientific and Technical Information (OSTI.GOV)
Clinton, Bentley; Johnson, Caley; Moriarty, Kristi
The Preliminary Assessment of Spatial Competition in the Market for E85 presentation and supplementary report from the U.S. Department of Energy’s National Renewable Energy Laboratory examine how the spacing of E85 fueling stations impacts E85 retail pricing. The analysis finds an inverse correlation between station density and E85 prices, with local competition putting downward pressure on E85 prices. A gas station with E85 whose nearest competitor is within a 0.5 mile radius is associated with a lower E85 price per gallon than an otherwise identical station with E85 whose nearest competitor is farther away. The analysis also finds a highermore » level of correlation between E85 and both E10 and wholesale gasoline prices than with ethanol costs. This indicates that E85 may, in fact, be priced with respect to its substitute fuel, and not based on the cost of its inputs. These findings help identify key trends and barriers in E85 markets and highlight data gaps that, if addressed, could help enable competitive E85 markets. The analysis was released in February 2017 and uses national and Minnesota-specific price data.« less
Hollands, Emma C; Dale, Tim J; Baxter, Andrew W; Meadows, Helen J; Powell, Andrew J; Clare, Jeff J; Trezise, Derek J
2009-08-01
Gamma-amino butyric acid (GABA)-activated Cl- channels are critical mediators of inhibitory postsynaptic potentials in the CNS. To date, rational design efforts to identify potent and selective GABA(A) subtype ligands have been hampered by the absence of suitable high-throughput screening approaches. The authors describe 384-well population patch-clamp (PPC) planar array electrophysiology methods for the study of GABA(A) receptor pharmacology. In HEK293 cells stably expressing human alpha1beta3gamma2 GABA(A) channels, GABA evoked outward currents at 0 mV of 1.05 +/- 0.08 nA, measured 8 s post GABA addition. The I(GABA) was linear and reversed close to the theoretical E(Cl) (-56 mV). Concentration-response curve analysis yielded a mean pEC(50) value of 5.4 and Hill slope of 1.5, and for a series of agonists, the rank order of potency was muscimol > GABA > isoguvacine. A range of known positive modulators, including diazepam and pentobarbital, produced concentration-dependent augmentation of the GABA EC( 20) response (1 microM). The competitive antagonists bicuculline and gabazine produced concentration-dependent, parallel, rightward displacement of GABA curves with pA(2) and slope values of 5.7 and 1.0 and 6.7 and 1.0, respectively. In contrast, picrotoxin (0.2-150 microM) depressed the maximal GABA response, implying a non-competitive antagonism. Overall, the pharmacology of human alpha1beta3gamma2 GABA(A) determined by PPC was highly similar to that obtained by conventional patch-clamp methods. In small-scale single-shot screens, Z' values of >0.5 were obtained in agonist, modulator, and antagonist formats with hit rates of 0% to 3%. The authors conclude that despite the inability of the method to resolve the peak agonist responses, PPC can rapidly and usefully quantify pharmacology for the alpha1beta3gamma2 GABA(A) isoform. These data suggest that PPC may be a valuable approach for a focused set and secondary screening of GABA(A) receptors and other slow ligand-gated ion channels.
Exploring the Sensitivity of Horn's Parallel Analysis to the Distributional Form of Random Data
ERIC Educational Resources Information Center
Dinno, Alexis
2009-01-01
Horn's parallel analysis (PA) is the method of consensus in the literature on empirical methods for deciding how many components/factors to retain. Different authors have proposed various implementations of PA. Horn's seminal 1965 article, a 1996 article by Thompson and Daniel, and a 2004 article by Hayton, Allen, and Scarpello all make assertions…
Accuracy of Revised and Traditional Parallel Analyses for Assessing Dimensionality with Binary Data
ERIC Educational Resources Information Center
Green, Samuel B.; Redell, Nickalus; Thompson, Marilyn S.; Levy, Roy
2016-01-01
Parallel analysis (PA) is a useful empirical tool for assessing the number of factors in exploratory factor analysis. On conceptual and empirical grounds, we argue for a revision to PA that makes it more consistent with hypothesis testing. Using Monte Carlo methods, we evaluated the relative accuracy of the revised PA (R-PA) and traditional PA…
Parallel peak pruning for scalable SMP contour tree computation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Carr, Hamish A.; Weber, Gunther H.; Sewell, Christopher M.
As data sets grow to exascale, automated data analysis and visualisation are increasingly important, to intermediate human understanding and to reduce demands on disk storage via in situ analysis. Trends in architecture of high performance computing systems necessitate analysis algorithms to make effective use of combinations of massively multicore and distributed systems. One of the principal analytic tools is the contour tree, which analyses relationships between contours to identify features of more than local importance. Unfortunately, the predominant algorithms for computing the contour tree are explicitly serial, and founded on serial metaphors, which has limited the scalability of this formmore » of analysis. While there is some work on distributed contour tree computation, and separately on hybrid GPU-CPU computation, there is no efficient algorithm with strong formal guarantees on performance allied with fast practical performance. Here in this paper, we report the first shared SMP algorithm for fully parallel contour tree computation, withfor-mal guarantees of O(lgnlgt) parallel steps and O(n lgn) work, and implementations with up to 10x parallel speed up in OpenMP and up to 50x speed up in NVIDIA Thrust.« less
Paramedir: A Tool for Programmable Performance Analysis
NASA Technical Reports Server (NTRS)
Jost, Gabriele; Labarta, Jesus; Gimenez, Judit
2004-01-01
Performance analysis of parallel scientific applications is time consuming and requires great expertise in areas such as programming paradigms, system software, and computer hardware architectures. In this paper we describe a tool that facilitates the programmability of performance metric calculations thereby allowing the automation of the analysis and reducing the application development time. We demonstrate how the system can be used to capture knowledge and intuition acquired by advanced parallel programmers in order to be transferred to novice users.
State-plane analysis of parallel resonant converter
NASA Technical Reports Server (NTRS)
Oruganti, R.; Lee, F. C.
1985-01-01
A method for analyzing the complex operation of a parallel resonant converter is developed, utilizing graphical state-plane techniques. The comprehensive mode analysis uncovers, for the first time, the presence of other complex modes besides the continuous conduction mode and the discontinuous conduction mode and determines their theoretical boundaries. Based on the insight gained from the analysis, a novel, high-frequency resonant buck converter is proposed. The voltage conversion ratio of the new converter is almost independent of load.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, L.; Li, Y.
2015-02-03
This paper analyzes the longitudinal space charge impedances of a round uniform beam inside a rectangular and parallel plate chambers using the image charge method. This analysis is valid for arbitrary wavelengths, and the calculations converge rapidly. The research shows that only a few of the image beams are needed to obtain a relative error less than 0.1%. The beam offset effect is also discussed in the analysis.
Data survey on the effect of product features on competitive advantage of selected firms in Nigeria.
Olokundun, Maxwell; Iyiola, Oladele; Ibidunni, Stephen; Falola, Hezekiah; Salau, Odunayo; Amaihian, Augusta; Peter, Fred; Borishade, Taiye
2018-06-01
The main objective of this study was to present a data article that investigates the effect product features on firm's competitive advantage. Few studies have examined how the features of a product could help in driving the competitive advantage of a firm. Descriptive research method was used. Statistical Package for Social Sciences (SPSS 22) was engaged for analysis of one hundred and fifty (150) valid questionnaire which were completed by small business owners registered under small and medium scale enterprises development of Nigeria (SMEDAN). Stratified and simple random sampling techniques were employed; reliability and validity procedures were also confirmed. The field data set is made publicly available to enable critical or extended analysis.
Self-optimizing approach for automated laser resonator alignment
NASA Astrophysics Data System (ADS)
Brecher, C.; Schmitt, R.; Loosen, P.; Guerrero, V.; Pyschny, N.; Pavim, A.; Gatej, A.
2012-02-01
Nowadays, the assembly of laser systems is dominated by manual operations, involving elaborate alignment by means of adjustable mountings. From a competition perspective, the most challenging problem in laser source manufacturing is price pressure, a result of cost competition exerted mainly from Asia. From an economical point of view, an automated assembly of laser systems defines a better approach to produce more reliable units at lower cost. However, the step from today's manual solutions towards an automated assembly requires parallel developments regarding product design, automation equipment and assembly processes. This paper introduces briefly the idea of self-optimizing technical systems as a new approach towards highly flexible automation. Technically, the work focuses on the precision assembly of laser resonators, which is one of the final and most crucial assembly steps in terms of beam quality and laser power. The paper presents a new design approach for miniaturized laser systems and new automation concepts for a robot-based precision assembly, as well as passive and active alignment methods, which are based on a self-optimizing approach. Very promising results have already been achieved, considerably reducing the duration and complexity of the laser resonator assembly. These results as well as future development perspectives are discussed.
Mujika, Iñigo; Chaouachi, Anis; Chamari, Karim
2010-06-01
A marked reduction in the training load in the lead-up to major competitions allows athletes to reduce the fatigue induced by intense training and improve competition performance. This tapered training phase is based on the reduction in training volume while maintaining pretaper training intensity and frequency. In parallel to training load reductions, nutritional strategies characterised by lowered energy intakes need to be implemented to match lowered energy expenditure. The Ramadan intermittent fast imposes constrained nutritional practices on Muslim athletes, inducing a shift to a greater reliance on fat oxidation to meet energy needs and a possible increase in protein breakdown. The training load is often reduced during Ramadan to match the absence of energy and fluid intake during daylight, which implies a risk of losing training induced adaptations. Should coaches and athletes decide to reduce the training load during Ramadan, the key role of training intensity in retaining training induced adaptations should be kept in mind. However, experienced elite Muslim athletes are able to maintain their usual training load during this month of intermittent fasting without decrements in measures of fitness and with only minor adverse effects.
Electrostatics-mediated α-chymotrypsin inhibition by functionalized single-walled carbon nanotubes.
Zhao, Daohui; Zhou, Jian
2017-01-04
The α-chymotrypsin (α-ChT) enzyme is extensively used for studying nanomaterial-induced enzymatic activity inhibition. A recent experimental study reported that carboxylized carbon nanotubes (CNTs) played an important role in regulating the α-ChT activity. In this study, parallel tempering Monte Carlo and molecular dynamics simulations were combined to elucidate the interactions between α-ChT and CNTs in relation to the CNT functional group density. The simulation results indicate that the adsorption and the driving force of α-ChT on different CNTs are contingent on the carboxyl density. Meanwhile, minor secondary structural changes are observed in adsorption processes. It is revealed that α-ChT interacts with pristine CNTs through hydrophobic forces and exhibits a non-competitive characteristic with the active site facing towards the solution; while it binds to carboxylized CNTs with the active pocket through a dominant electrostatic association, which causes enzymatic activity inhibition in a competitive-like mode. These findings are in line with experimental results, and well interpret the activity inhibition of α-ChT at the molecular level. Moreover, this study would shed light on the detailed mechanism of specific recognition and regulation of α-ChT by other functionalized nanomaterials.
INTERDEPENDENT SUPERIORITY AND INFERIORITY FEELINGS
Ingham, Harrington V.
1949-01-01
It is postulated that in neurotic persons who have unrealistic feelings of superiority and inferiority the two are interdependent. This is a departure from the concept of previous observers that either one or the other is primary and its opposite is overcompensation. The author postulates considerable parallelism, with equal importance for each. He submits that the neurotic person forms two logic-resistant compartments for the two opposed self-estimates and that treatment which makes inroads of logic upon one compartment, simultaneously does so upon the other. Two examples are briefly reported. The neurotic benefits sought in exaggeration of capability are the same as those sought in insistence upon inferiority: Presumption of superiority at once bids for approbation and delivers the subject from the need to prove himself worthy of it in dreaded competition; exaggeration of incapability baits sympathy and makes competition unnecessary because failure is conceded. Some of the characteristics of abnormal self-estimates that distinguish them from normal are: Preoccupation with self, resistance to logical explanation of personality problems, inconsistency in reasons for beliefs in adequacy on the one hand and inadequacy on the other, unreality, rationalization of faults, and difficulty and vacillation in the selection of adequate goals. PMID:15390573
A neural-network-based approach to the double traveling salesman problem.
Plebe, Alessio; Anile, Angelo Marcello
2002-02-01
The double traveling salesman problem is a variation of the basic traveling salesman problem where targets can be reached by two salespersons operating in parallel. The real problem addressed by this work concerns the optimization of the harvest sequence for the two independent arms of a fruit-harvesting robot. This application poses further constraints, like a collision-avoidance function. The proposed solution is based on a self-organizing map structure, initialized with as many artificial neurons as the number of targets to be reached. One of the key components of the process is the combination of competitive relaxation with a mechanism for deleting and creating artificial neurons. Moreover, in the competitive relaxation process, information about the trajectory connecting the neurons is combined with the distance of neurons from the target. This strategy prevents tangles in the trajectory and collisions between the two tours. Results of tests indicate that the proposed approach is efficient and reliable for harvest sequence planning. Moreover, the enhancements added to the pure self-organizing map concept are of wider importance, as proved by a traveling salesman problem version of the program, simplified from the double version for comparison.
Gomes, Andreia Maria da Anunciação; Azevedo, Sandra Maria Feliciano de Oliveira e; Lürling, Miquel
2015-01-01
We studied the effect of temperature (18 and 30°C) on growth and on the exploitation and interference competition of three species: Microcystis aeruginosa (MIJAC), Planktothrix agardhii (PAT), and Cyclotella meneghiniana (CCAP). Coculturing the organisms in batch systems allowed for the examination of both competitive interactions, while the interference competition was studied in cross-cultures. The experiments were done during 10–12 days, and samples were taken for chlorophyll-a analysis, using PHYTO-PAM. The temperature did not influence exploitation competition between MIJAC and other competitors and it was the best competitor in both temperatures. PAT presented higher growth rates than CCAP in competition at 18 and 30°C. The temperature influenced the interference competition. The growth of MIJAC was favored in strains exudates at 30°C, while CCAP was favored at 18°C, revealing that the optimum growth temperature was important to establish the competitive superiority. Therefore, we can propose two hypotheses: (i) different temperatures may results in production of distinct compounds that influence the competition among phytoplankton species and (ii) the target species may have different vulnerability to these compounds depending on the temperature. At last, we suggest that both the sensitivity and the physiological status of competing species can determine their lasting coexistence. PMID:26380369
Parallel digital forensics infrastructure.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liebrock, Lorie M.; Duggan, David Patrick
2009-10-01
This report documents the architecture and implementation of a Parallel Digital Forensics infrastructure. This infrastructure is necessary for supporting the design, implementation, and testing of new classes of parallel digital forensics tools. Digital Forensics has become extremely difficult with data sets of one terabyte and larger. The only way to overcome the processing time of these large sets is to identify and develop new parallel algorithms for performing the analysis. To support algorithm research, a flexible base infrastructure is required. A candidate architecture for this base infrastructure was designed, instantiated, and tested by this project, in collaboration with New Mexicomore » Tech. Previous infrastructures were not designed and built specifically for the development and testing of parallel algorithms. With the size of forensics data sets only expected to increase significantly, this type of infrastructure support is necessary for continued research in parallel digital forensics. This report documents the implementation of the parallel digital forensics (PDF) infrastructure architecture and implementation.« less
A model for optimizing file access patterns using spatio-temporal parallelism
DOE Office of Scientific and Technical Information (OSTI.GOV)
Boonthanome, Nouanesengsy; Patchett, John; Geveci, Berk
2013-01-01
For many years now, I/O read time has been recognized as the primary bottleneck for parallel visualization and analysis of large-scale data. In this paper, we introduce a model that can estimate the read time for a file stored in a parallel filesystem when given the file access pattern. Read times ultimately depend on how the file is stored and the access pattern used to read the file. The file access pattern will be dictated by the type of parallel decomposition used. We employ spatio-temporal parallelism, which combines both spatial and temporal parallelism, to provide greater flexibility to possible filemore » access patterns. Using our model, we were able to configure the spatio-temporal parallelism to design optimized read access patterns that resulted in a speedup factor of approximately 400 over traditional file access patterns.« less
Exploiting parallel computing with limited program changes using a network of microcomputers
NASA Technical Reports Server (NTRS)
Rogers, J. L., Jr.; Sobieszczanski-Sobieski, J.
1985-01-01
Network computing and multiprocessor computers are two discernible trends in parallel processing. The computational behavior of an iterative distributed process in which some subtasks are completed later than others because of an imbalance in computational requirements is of significant interest. The effects of asynchronus processing was studied. A small existing program was converted to perform finite element analysis by distributing substructure analysis over a network of four Apple IIe microcomputers connected to a shared disk, simulating a parallel computer. The substructure analysis uses an iterative, fully stressed, structural resizing procedure. A framework of beams divided into three substructures is used as the finite element model. The effects of asynchronous processing on the convergence of the design variables are determined by not resizing particular substructures on various iterations.