NASA Astrophysics Data System (ADS)
Lopez-Rendon, X.; Zhang, G.; Bosmans, H.; Oyen, R.; Zanca, F.
2014-03-01
Purpose: To estimate the consequences on dosimetric applications when a CT bowtie filter is modeled by means of full beam hardening versus partial beam hardening. Method: A model of source and filtration for a CT scanner as developed by Turner et. al. [1] was implemented. Specific exposures were measured with the stationary CT X-ray tube in order to assess the equivalent thickness of Al of the bowtie filter as a function of the fan angle. Using these thicknesses, the primary beam attenuation factors were calculated from the energy dependent photon mass attenuation coefficients and used to include beam hardening in the spectrum. This was compared to a potentially less computationally intensive approach, which accounts only partially for beam hardening, by giving the photon spectrum a global (energy independent) fan angle specific weighting factor. Percentage differences between the two methods were quantified by calculating the dose in air after passing several water equivalent thicknesses representative for patients having different BMI. Specifically, the maximum water equivalent thickness of the lateral and anterior-posterior dimension and of the corresponding (half) effective diameter were assessed. Results: The largest percentage differences were found for the thickest part of the bowtie filter and they increased with patient size. For a normal size patient they ranged from 5.5% at half effective diameter to 16.1% for the lateral dimension; for the most obese patient they ranged from 7.7% to 19.3%, respectively. For a complete simulation of one rotation of the x-ray tube, the proposed method was 12% faster than the complete simulation of the bowtie filter. Conclusion: The need for simulating the beam hardening of the bow tie filter in Monte Carlo platforms for CT dosimetry will depend on the required accuracy.
Measuring partial fluorescence yield using filtered detectors.
Boyko, T D; Green, R J; Moewes, A; Regier, T Z
2014-07-01
Typically, X-ray absorption near-edge structure measurements aim to probe the linear attenuation coefficient. These measurements are often carried out using partial fluorescence yield techniques that rely on detectors having photon energy discrimination improving the sensitivity and the signal-to-background ratio of the measured spectra. However, measuring the partial fluorescence yield in the soft X-ray regime with reasonable efficiency requires solid-state detectors, which have limitations due to the inherent dead-time while measuring. Alternatively, many of the available detectors that are not energy dispersive do not suffer from photon count rate limitations. A filter placed in front of one of these detectors will make the energy-dependent efficiency non-linear, thereby changing the responsivity of the detector. It is shown that using an array of filtered X-ray detectors is a viable method for measuring soft X-ray partial fluorescence yield spectra without dead-time. The feasibility of this technique is further demonstrated using α-Fe2O3 as an example and it is shown that this detector technology could vastly improve the photon collection efficiency at synchrotrons and that these detectors will allow experiments to be completed with a much lower photon flux reducing X-ray-induced damage.
Application of the Radon-FCL approach to seismic random noise suppression and signal preservation
NASA Astrophysics Data System (ADS)
Meng, Fanlei; Li, Yue; Liu, Yanping; Tian, Yanan; Wu, Ning
2016-08-01
The fractal conservation law (FCL) is a linear partial differential equation that is modified by an anti-diffusive term of lower order. The analysis indicated that this algorithm could eliminate high frequencies and preserve or amplify low/medium-frequencies. Thus, this method is quite suitable for the simultaneous noise suppression and enhancement or preservation of seismic signals. However, the conventional FCL filters seismic data only along the time direction, thereby ignoring the spatial coherence between neighbouring traces, which leads to the loss of directional information. Therefore, we consider the development of the conventional FCL into the time-space domain and propose a Radon-FCL approach. We applied a Radon transform to implement the FCL method in this article; performing FCL filtering in the Radon domain achieves a higher level of noise attenuation. Using this method, seismic reflection events can be recovered with the sacrifice of fewer frequency components while effectively attenuating more random noise than conventional FCL filtering. Experiments using both synthetic and common shot point data demonstrate the advantages of the Radon-FCL approach versus the conventional FCL method with regard to both random noise attenuation and seismic signal preservation.
Foltyn, Stephen R.
1988-01-01
The disclosure relates to low loss, high power variable attenuators comprng one or more transmissive and/or reflective multilayer dielectric filters. The attenuator is particularly suitable to use with unpolarized lasers such as excimer lasers. Beam attenuation is a function of beam polarization and the angle of incidence between the beam and the filter and is controlled by adjusting the angle of incidence the beam makes to the filter or filters. Filters are selected in accordance with beam wavelength.
Foltyn, S.R.
1987-05-29
The disclosure relates to low loss, high power variable attenuators comprising one or more transmissive and/or reflective multilayer dielectric filters. The attenuator is particularly suitable to use with unpolarized lasers such as excimer lasers. Beam attenuation is a function of beam polarization and the angle of incidence between the beam and the filter and is controlled by adjusting the angle of incidence the beam makes to the filter or filters. Filters are selected in accordance with beam wavelength. 9 figs.
Steinmeyer, P.A.
1992-11-24
A radiation filter for filtering radiation beams of wavelengths within a preselected range of wavelengths comprises a radiation transmissive substrate and an attenuating layer deposited on the substrate. The attenuating layer may be deposited by a sputtering process or a vacuum process. Beryllium may be used as the radiation transmissive substrate. In addition, a second radiation filter comprises an attenuating layer interposed between a pair of radiation transmissive layers. 4 figs.
Steinmeyer, Peter A.
1992-11-24
A radiation filter for filtering radiation beams of wavelengths within a preselected range of wavelengths comprises a radiation transmissive substrate and an attenuating layer deposited on the substrate. The attenuating layer may be deposited by a sputtering process or a vacuum process. Beryllium may be used as the radiation transmissive substrate. In addition, a second radiation filter comprises an attenuating layer interposed between a pair of radiation transmissive layers.
Komor, Stephen Charles; Hansen, Donald S.
2003-01-01
Attenuation of cattle feedlot runoff in two grass-covered filter strips in Minnesota was estimated by measuring chemical loads into and out of the strips. Filter strips of the Bock and Sanborn sites were 60-m long and 20-m wide and received runoff from cattle feedlots that supported 35 and 225 cattle, respectively. Feedlot and filter-strip runoff were measured using flumes with stage sensors. Water samples were collected using automated samplers. Attenuation values were calculated from four storm-runoff events. Ground water sampled beneath and outside the filter strips indicated some infiltration losses of sulfate, chloride, and nitrogen at the Bock site where soil permeability was greater than at the Sanborn site. Chemical constituents in filter-strip runoff, and their corresponding ranges of attenuation were as follows: chemical oxygen demand, 30–81 percent; dissolved chloride, 6–79 percent; dissolved sulfate, -3–82 percent; dissolved ammonia nitrogen, 33–80 percent; suspended ammonia plus organic nitrogen, 29–85 percent; dissolved organic nitrogen, 14–75 percent; suspended phosphorus, 24–82 percent; dissolved phosphorus, 14–72 percent; and fecal coliform bacteria, 18–79 percent. The ranges seem to be affected by barriers of direct contact of the runoff water with the soil. This varies seasonally by coverage of the soil by ice in winter and vegetation in summer months. Greater attenuation values occurred in October and May when mats of wilted, flat-lying grass covered the filter strips; attenuation values were less during the summer when tall growing grass covered the filter strips.
Study on the fabrication of low-pass metal powder filters for use at cryogenic temperatures
NASA Astrophysics Data System (ADS)
Lee, Sung Hoon; Lee, Soon-Gul
2016-08-01
We fabricated compact low-pass stainless-steel powder filters for use in low-noise measurements at cryogenic temperatures and investigated their attenuation characteristics for different wire lengths, filter shapes, and preparation methods at frequencies up to 20 GHz. We used nominally 30- μm-sized SUS 304L powder and mixed it with Stycast 2850FT (Emerson and Cumming) with catalyst 23LV. A 0.1-mm insulated copper wire was wound on preformed powder-mixture spools in the shape of a right-circular cylinder, a flattened elliptic cylinder and a toroid, and the coils were encapsulated in metal tubes or boxes filled with the powder mixture. All the fabricated powder filters showed a large attenuation at high frequencies with a cut-off frequency near 1 GHz. However, the toroidal filter showed prominent ripples corresponding to resonance modes in the 0.5-m-long coil wire. A filter with a 2:1 powder/epoxy mixture mass ratio and a wire length of 1.53 m showed an attenuation of -93 dB at 4 GHz, and the attenuation was linearly proportional to the wire's length. As the powder-to-epoxy ratio was increased, the high-frequency attenuation increased. An equally-spaced single-layer coil structure was found to be more efficient in attenuation than a double-layer coil. The geometry of the metal filter's case affected the noise ripples, with the least noise being found for a circular tube.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Erlangga, Mokhammad Puput
Separation between signal and noise, incoherent or coherent, is important in seismic data processing. Although we have processed the seismic data, the coherent noise is still mixing with the primary signal. Multiple reflections are a kind of coherent noise. In this research, we processed seismic data to attenuate multiple reflections in the both synthetic and real seismic data of Mentawai. There are several methods to attenuate multiple reflection, one of them is Radon filter method that discriminates between primary reflection and multiple reflection in the τ-p domain based on move out difference between primary reflection and multiple reflection. However, inmore » case where the move out difference is too small, the Radon filter method is not enough to attenuate the multiple reflections. The Radon filter also produces the artifacts on the gathers data. Except the Radon filter method, we also use the Wave Equation Multiple Elimination (WEMR) method to attenuate the long period multiple reflection. The WEMR method can attenuate the long period multiple reflection based on wave equation inversion. Refer to the inversion of wave equation and the magnitude of the seismic wave amplitude that observed on the free surface, we get the water bottom reflectivity which is used to eliminate the multiple reflections. The WEMR method does not depend on the move out difference to attenuate the long period multiple reflection. Therefore, the WEMR method can be applied to the seismic data which has small move out difference as the Mentawai seismic data. The small move out difference on the Mentawai seismic data is caused by the restrictiveness of far offset, which is only 705 meter. We compared the real free multiple stacking data after processing with Radon filter and WEMR process. The conclusion is the WEMR method can more attenuate the long period multiple reflection than the Radon filter method on the real (Mentawai) seismic data.« less
NASA Astrophysics Data System (ADS)
Lee, Sung Hoon; Lee, Soon-Gul
2018-04-01
We fabricated low-pass metal powder filters for use in low-noise measurements at cryogenic temperatures and investigated their attenuation characteristics for different wire-turn densities, metalpowder shapes, and preparation methods at frequencies up to 20 GHz. We used nominally 30-μmsized stainless-steel 304L powder and mixed it with low-temperature binders. The low-temperature binders used were Stycast 2850FT (Emerson and Cumming) with catalyst 23LV and GE-7031 varnish. A 0.1-mm insulated copper wire was wound on preformed powder-mixture bobbins in the shape of a circular rod and was encapsulated in metal tubes with the powder mixture. All the fabricated powder filters showed a large attenuation at high frequencies with a cut-off frequency near 1 GHz. For filters of the same wire length, a lower wiring density showed a larger attenuation, which implies that the amount of powder in close contact with the wire determines the attenuation. Filters made of a powder/varnish mixture showed significantly larger attenuations than those of a powder/stycast mixture, and the attenuation improved with increasing powder ratio in the mixture. The low-temperature thermal conductivities of a 2 : 1 powder/Stycast mixture and a 5 : 1 powder/varnish mixture showed similar values at temperatures up to 4.2 K.
Shi, Z.; Tian, G.; Dong, S.; Xia, J.; He, H.; ,
2004-01-01
In a desert area, it is difficult to couple geophones with dry sands. A low and depression velocity layer can seriously attenuate high frequency components of seismic data. Therefore, resolution and signal-to-noise (S/N) ratio of seismic data deteriorate. To enhance resolution and S/N ratio of seismic data, we designed a coupling compensatory inverse filter by using the single trace seismic data from Seismic Wave Detect System (SWDS) and common receivers on equal conditions. We designed an attenuating compensatory inverse filter by using seismic data from a microseismogram log. At last, in order to convert a shot gather from common receivers to a shot gather from SWDS, we applied the coupling compensatory inverse filter to the shot gather from common receivers. And then we applied the attenuating compensatory inverse filter to the coupling stacked seismic data to increase its resolution and S/N ratio. The results show that the resolution of seismic data from common receivers after processing by using the coupling compensatory inverse filter is nearly comparable with that of data from SWDS. It is also found that the resolution and S/N ratio have been enhanced after the use of attenuating compensatory inverse filter. From the results, we can conclude that the filters can compensate high frequencies of seismic data. Moreover, the low frequency changed nearly.
Fundamental techniques for resolution enhancement of average subsampled images
NASA Astrophysics Data System (ADS)
Shen, Day-Fann; Chiu, Chui-Wen
2012-07-01
Although single image resolution enhancement, otherwise known as super-resolution, is widely regarded as an ill-posed inverse problem, we re-examine the fundamental relationship between a high-resolution (HR) image acquisition module and its low-resolution (LR) counterpart. Analysis shows that partial HR information is attenuated but still exists, in its LR version, through the fundamental averaging-and-subsampling process. As a result, we propose a modified Laplacian filter (MLF) and an intensity correction process (ICP) as the pre and post process, respectively, with an interpolation algorithm to partially restore the attenuated information in a super-resolution (SR) enhanced image image. Experiments show that the proposed MLF and ICP provide significant and consistent quality improvements on all 10 test images with three well known interpolation methods including bilinear, bi-cubic, and the SR graphical user interface program provided by Ecole Polytechnique Federale de Lausanne. The proposed MLF and ICP are simple in implementation and generally applicable to all average-subsampled LR images. MLF and ICP, separately or together, can be integrated into most interpolation methods that attempt to restore the original HR contents. Finally, the idea of MLF and ICP can also be applied for average, subsampled one-dimensional signal.
NASA Astrophysics Data System (ADS)
Swetadri Vasan, S. N.; Pope, Liza; Ionita, Ciprian N.; Titus, A. H.; Bednarek, D. R.; Rudin, S.
2013-03-01
A novel dose reduction technique for fluoroscopic interventions involving a combination of a material x-ray region of interest (ROI) attenuator and spatially different, temporally variable ROI temporal recursive filter, was used to guide the catheter to the ROI in three live animal studies, two involving rabbits and one involving a sheep. In the two rabbit studies presented , a catheter was guided to the entrance of the carotid artery. With the added ROI attenuator the image under the high attenuation region is very noisy. By using temporal filtering with a filter weight of 0.6 on previous frames, the noise is reduced. In the sheep study the catheter was guided to the descending aorta of the animal. The sheep offered a relatively higher attenuation to the incident x-rays and thus a higher temporal filter weight of 0.8 on previous frames was used during the procedure to reduce the noise to levels acceptable by the interventionalist. The image sequences from both studies show that significant dose reduction of 5-6 times can be achieved with acceptable image quality outside the ROI by using the above mentioned technique. Even though the temporal filter weighting outside the ROI is higher, the consequent lag does not prevent perception of catheter movement.
Combustion-derived nanoparticulate induces the adverse vascular effects of diesel exhaust inhalation
Mills, Nicholas L.; Miller, Mark R.; Lucking, Andrew J.; Beveridge, Jon; Flint, Laura; Boere, A. John F.; Fokkens, Paul H.; Boon, Nicholas A.; Sandstrom, Thomas; Blomberg, Anders; Duffin, Rodger; Donaldson, Ken; Hadoke, Patrick W.F.; Cassee, Flemming R.; Newby, David E.
2011-01-01
Aim Exposure to road traffic and air pollution may be a trigger of acute myocardial infarction, but the individual pollutants responsible for this effect have not been established. We assess the role of combustion-derived-nanoparticles in mediating the adverse cardiovascular effects of air pollution. Methods and results To determine the in vivo effects of inhalation of diesel exhaust components, 16 healthy volunteers were exposed to (i) dilute diesel exhaust, (ii) pure carbon nanoparticulate, (iii) filtered diesel exhaust, or (iv) filtered air, in a randomized double blind cross-over study. Following each exposure, forearm blood flow was measured during intra-brachial bradykinin, acetylcholine, sodium nitroprusside, and verapamil infusions. Compared with filtered air, inhalation of diesel exhaust increased systolic blood pressure (145 ± 4 vs. 133 ± 3 mmHg, P< 0.05) and attenuated vasodilatation to bradykinin (P= 0.005), acetylcholine (P= 0.008), and sodium nitroprusside (P< 0.001). Exposure to pure carbon nanoparticulate or filtered exhaust had no effect on endothelium-dependent or -independent vasodilatation. To determine the direct vascular effects of nanoparticulate, isolated rat aortic rings (n= 6–9 per group) were assessed in vitro by wire myography and exposed to diesel exhaust particulate, pure carbon nanoparticulate and vehicle. Compared with vehicle, diesel exhaust particulate (but not pure carbon nanoparticulate) attenuated both acetylcholine (P< 0.001) and sodium-nitroprusside (P= 0.019)-induced vasorelaxation. These effects were partially attributable to both soluble and insoluble components of the particulate. Conclusion Combustion-derived nanoparticulate appears to predominately mediate the adverse vascular effects of diesel exhaust inhalation. This provides a rationale for testing environmental health interventions targeted at reducing traffic-derived particulate emissions. PMID:21753226
Dissipative cryogenic filters with zero dc resistance.
Bluhm, Hendrik; Moler, Kathryn A
2008-01-01
The authors designed, implemented, and tested cryogenic rf filters with zero dc resistance, based on wires with a superconducting core inside a resistive sheath. The superconducting core allows low frequency currents to pass with negligible dissipation. Signals above the cutoff frequency are dissipated in the resistive part due to their small skin depth. The filters consist of twisted wire pairs shielded with copper tape. Above approximately 1 GHz, the attenuation is exponential in omega, as typical for skin depth based rf filters. By using additional capacitors of 10 nF per line, an attenuation of at least 45 dB above 10 MHz can be obtained. Thus, one single filter stage kept at mixing chamber temperature in a dilution refrigerator is sufficient to attenuate room temperature black body radiation to levels corresponding to 10 mK above about 10 MHz.
Wang, Hongyu; He, Jiajie; Yang, Kai
2010-01-01
This study evaluated the partial nitrification performances of two biofilm filters over a synthetic non-ammonium-rich wastewater at a 20°C room temperature under both limited DO (∼2.0 mg/L) and unlimited DO (∼4.0 mg/L) conditions. The two filters were each of 80 cm long and used different biofilm carriers: activated carbon and ceramic granule. Results showed that partial nitrification was accomplished for both filters under the limited DO condition. However, the effluent NO(2)-N was higher in the ceramic granule filter than in the activated carbon filter, and was less susceptible to the influent COD/N changes. Further investigation into the water phase COD and NH(4)-N depth profiles and bacteria population within the two filters showed that by putting upper filter layer (upstream) to confront relatively higher influent COD/N ratios, the filtration process naturally put lower filter layers (downstream) relatively more favorable for nitrifying bacteria (ammonia oxidizing bacteria in this study) to prosper, making the filter depth left for nitrification a crucial factor for the effectiveness of nitrification with a filter. The potentially different porous flow velocities of the two filters might be the reason to cause their different partial nitrification performances, with a lower porous flow velocity (the ceramic granule filter) favoring partial nitrification more. In summation, DO, filter depth, and filtration speed should be played together to successfully operate a biofilm filter for partial nitrification.
Stereo Sound Field Controller Design Using Partial Model Matching on the Frequency Domain
NASA Astrophysics Data System (ADS)
Kumon, Makoto; Miike, Katsuhiro; Eguchi, Kazuki; Mizumoto, Ikuro; Iwai, Zenta
The objective of sound field control is to make the acoustic characteristics of a listening room close to those of the desired system. Conventional methods apply feedforward controllers, such as digital filters, to achieve this objective. However, feedback controllers are also necessary in order to attenuate noise or to compensate the uncertainty of the acoustic characteristics of the listening room. Since acoustic characteristics are well modeled on the frequency domain, it is efficient to design controllers with respect to frequency responses, but it is difficult to design a multi input multi output (MIMO) control system on a wide frequency domain. In the present study, a partial model matching method on the frequency domain was adopted because this method requires only sampled data, rather than complex mathematical models of the plant, in order to design controllers for MIMO systems. The partial model matching method was applied to design two-degree-of-freedom controllers for acoustic equalization and noise reduction. Experiments demonstrated effectiveness of the proposed method.
Highly Concentrated Seed-Mediated Synthesis of Monodispersed Gold Nanorods (Postprint)
2017-07-17
imaging, therapeutics and sensors, to large area coatings, filters , and optical attenuators. Development of the latter technologies has been hindered by...sensors, to large area coatings, filters , and optical attenuators. Development of the latter technologies has been hindered by the lack of cost-effective...challenges the utilization of Au-NRs in a diverse array of technologies, ranging from therapeutics, imaging and sensors, to large area coatings, filters and
NASA Astrophysics Data System (ADS)
Nazifah, A.; Norhanna, S.; Shah, S. I.; Zakaria, A.
2014-11-01
This study aimed to investigate the effects of material filter technique on Tc-99m spectra and performance parameters of Philip ADAC forte dual head gamma camera. Thickness of material filter was selected on the basis of percentage attenuation of various gamma ray energies by different thicknesses of zinc material. A cylindrical source tank of NEMA single photon emission computed tomography (SPECT) Triple Line Source Phantom filled with water and Tc-99m radionuclide injected was used for spectra, uniformity and sensitivity measurements. Vinyl plastic tube was used as a line source for spatial resolution. Images for uniformity were reconstructed by filtered back projection method. Butterworth filter of order 5 and cut off frequency 0.35 cycles/cm was selected. Chang's attenuation correction method was applied by selecting 0.13/cm linear attenuation coefficient. Count rate was decreased with material filter from the compton region of Tc-99m energy spectrum, also from the photopeak region. Spatial resolution was improved. However, uniformity of tomographic image was equivocal, and system volume sensitivity was reduced by material filter. Material filter improved system's spatial resolution. Therefore, the technique may be used for phantom studies to improve the image quality.
NASA Astrophysics Data System (ADS)
Abolfazl Hosseini, Seyed; Javaherian, Abdolrahim; Hassani, Hossien; Torabi, Siyavash; Sadri, Maryam
2015-06-01
Ground roll, which is a Rayleigh surface wave that exists in land seismic data, may mask reflections. Sometimes ground roll is spatially aliased. Attenuation of aliased ground roll is of importance in seismic data processing. Different methods have been developed to attenuate ground roll. The shearlet transform is a directional and multidimensional transform that generates subimages of an input image in different directions and scales. Events with different dips are separated in these subimages. In this study, the shearlet transform is used to attenuate the aliased ground roll. To do this, a shot record is divided into several segments, and the appropriate mute zone is defined for all segments. The shearlet transform is applied to each segment. The subimages related to the non-aliased and aliased ground roll are identified by plotting the energy distributions of subimages with visual checking. Then, muting filters are used on selected subimages. The inverse shearlet transform is applied to the filtered segment. This procedure is repeated for all segments. Finally, all filtered segments are merged using the Hanning window. This method of aliased ground roll attenuation was tested on a synthetic dataset and a field shot record from the west of Iran. The synthetic shot record included strong aliased ground roll, whereas the field shot record did not. To produce the strong aliased ground roll on the field shot record, the data were resampled in the offset direction from 30 to 60 m. To show the performance of the shearlet transform in attenuating the aliased ground roll, we compared the shearlet transform with the f-k filtering and curvelet transform. We showed that the performance of the shearlet transform in the aliased ground roll attenuation is better than that of the f-k filtering and curvelet transform in both the synthetic and field shot records. However, when the dip and frequency content of the aliased ground roll are the same as the reflections, ability of the shearlet transform is limited in attenuating the aliased ground roll.
The Lockheed alternate partial polarizer universal filter
NASA Technical Reports Server (NTRS)
Title, A. M.
1976-01-01
A tunable birefringent filter using an alternate partial polarizer design has been built. The filter has a transmission of 38% in polarized light. Its full width at half maximum is .09A at 5500A. It is tunable from 4500 to 8500A by means of stepping motor actuated rotating half wave plates and polarizers. Wave length commands and thermal compensation commands are generated by a PPD 11/10 minicomputer. The alternate partial polarizer universal filter is compared with the universal birefringent filter and the design techniques, construction methods, and filter performance are discussed in some detail. Based on the experience of this filter some conclusions regarding the future of birefringent filters are elaborated.
Resolution Enhancement In Ultrasonic Imaging By A Time-Varying Filter
NASA Astrophysics Data System (ADS)
Ching, N. H.; Rosenfeld, D.; Braun, M.
1987-09-01
The study reported here investigates the use of a time-varying filter to compensate for the spreading of ultrasonic pulses due to the frequency dependence of attenuation by tissues. The effect of this pulse spreading is to degrade progressively the axial resolution with increasing depth. The form of compensation required to correct for this effect is impossible to realize exactly. A novel time-varying filter utilizing a bank of bandpass filters is proposed as a realizable approximation of the required compensation. The performance of this filter is evaluated by means of a computer simulation. The limits of its application are discussed. Apart from improving the axial resolution, and hence the accuracy of axial measurements, the compensating filter could be used in implementing tissue characterization algorithms based on attenuation data.
NASA Technical Reports Server (NTRS)
Title, A. M.
1978-01-01
Filter includes partial polarizer between birefrigent elements. Plastic film on partial polarizer compensates for any polarization rotation by partial polarizer. Two quarter-wave plates change incident, linearly polarized light into elliptically polarized light.
An OTA-C filter for ECG acquisition systems with highly linear range and less passband attenuation
NASA Astrophysics Data System (ADS)
Jihai, Duan; Chuang, Lan; Weilin, Xu; Baolin, Wei
2015-05-01
A fifth order operational transconductance amplifier-C (OTA-C) Butterworth type low-pass filter with highly linear range and less passband attenuation is presented for wearable bio-telemetry monitoring applications in a UWB wireless body area network. The source degeneration structure applied in typical small transconductance circuit is improved to provide a highly linear range for the OTA-C filter. Moreover, to reduce the passband attenuation of the filter, a cascode structure is employed as the output stage of the OTA. The OTA-based circuit is operated in weak inversion due to strict power limitation in the biomedical chip. The filter is fabricated in a SMIC 0.18-μm CMOS process. The measured results for the filter have shown a passband gain of -6.2 dB, while the -3-dB frequency is around 276 Hz. For the 0.8 VPP sinusoidal input at 100 Hz, a total harmonic distortion (THD) of -56.8 dB is obtained. An electrocardiogram signal with noise interference is fed into this chip to validate the function of the designed filter. Project supported by the National Natural Science Foundation of China (Nos. 61161003, 61264001, 61166004) and the Guangxi Natural Science Foundation (No. 2013GXNSFAA019333).
Iterative dip-steering median filter
NASA Astrophysics Data System (ADS)
Huo, Shoudong; Zhu, Weihong; Shi, Taikun
2017-09-01
Seismic data are always contaminated with high noise components, which present processing challenges especially for signal preservation and its true amplitude response. This paper deals with an extension of the conventional median filter, which is widely used in random noise attenuation. It is known that the standard median filter works well with laterally aligned coherent events but cannot handle steep events, especially events with conflicting dips. In this paper, an iterative dip-steering median filter is proposed for the attenuation of random noise in the presence of multiple dips. The filter first identifies the dominant dips inside an optimized processing window by a Fourier-radial transform in the frequency-wavenumber domain. The optimum size of the processing window depends on the intensity of random noise that needs to be attenuated and the amount of signal to be preserved. It then applies median filter along the dominant dip and retains the signals. Iterations are adopted to process the residual signals along the remaining dominant dips in a descending sequence, until all signals have been retained. The method is tested by both synthetic and field data gathers and also compared with the commonly used f-k least squares de-noising and f-x deconvolution.
The nonstationary strain filter in elastography: Part I. Frequency dependent attenuation.
Varghese, T; Ophir, J
1997-01-01
The accuracy and precision of the strain estimates in elastography depend on a myriad number of factors. A clear understanding of the various factors (noise sources) that plague strain estimation is essential to obtain quality elastograms. The nonstationary variation in the performance of the strain filter due to frequency-dependent attenuation and lateral and elevational signal decorrelation are analyzed in this and the companion paper for the cross-correlation-based strain estimator. In this paper, we focus on the role of frequency-dependent attenuation in the performance of the strain estimator. The reduction in the signal-to-noise ratio (SNRs) in the RF signal, and the center frequency and bandwidth downshift with frequency-dependent attenuation are incorporated into the strain filter formulation. Both linear and nonlinear frequency dependence of attenuation are theoretically analyzed. Monte-Carlo simulations are used to corroborate the theoretically predicted results. Experimental results illustrate the deterioration in the precision of the strain estimates with depth in a uniformly elastic phantom. Theoretical, simulation and experimental results indicate the importance of high SNRs values in the RF signals, because the strain estimation sensitivity, elastographic SNRe and dynamic range deteriorate rapidly with a decrease in the SNRs. In addition, a shift in the strain filter toward higher strains is observed at large depths in tissue due to the center frequency downshift.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sayre, D. B., E-mail: sayre4@llnl.gov; Barbosa, F.; Caggiano, J. A.
Sixty-four neutral density filters constructed of metal plates with 88 apertures of varying diameter have been radiographed with a soft x-ray source and CCD camera at National Security Technologies, Livermore. An analysis of the radiographs fits the radial dependence of the apertures’ image intensities to sigmoid functions, which can describe the rapidly decreasing intensity towards the apertures’ edges. The fitted image intensities determine the relative attenuation value of each filter. Absolute attenuation values of several imaged filters, measured in situ during calibration experiments, normalize the relative quantities which are now used in analyses of neutron spectrometer data at the Nationalmore » Ignition Facility.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sayre, D. B.; Barbosa, F.; Caggiano, J. A.
Sixty-four neutral density filters constructed of metal plates with 88 apertures of varying diameter have been radiographed with a soft x-ray source and CCD camera at National Security Technologies, Livermore. An analysis of the radiographs fits the radial dependence of the apertures’ image intensities to sigmoid functions, which can describe the rapidly decreasing intensity towards the apertures’ edges. Here, the fitted image intensities determine the relative attenuation value of each filter. Absolute attenuation values of several imaged filters, measured in situ during calibration experiments, normalize the relative quantities which are now used in analyses of neutron spectrometer data at themore » National Ignition Facility.« less
Sayre, D. B.; Barbosa, F.; Caggiano, J. A.; ...
2016-07-26
Sixty-four neutral density filters constructed of metal plates with 88 apertures of varying diameter have been radiographed with a soft x-ray source and CCD camera at National Security Technologies, Livermore. An analysis of the radiographs fits the radial dependence of the apertures’ image intensities to sigmoid functions, which can describe the rapidly decreasing intensity towards the apertures’ edges. Here, the fitted image intensities determine the relative attenuation value of each filter. Absolute attenuation values of several imaged filters, measured in situ during calibration experiments, normalize the relative quantities which are now used in analyses of neutron spectrometer data at themore » National Ignition Facility.« less
Sayre, D B; Barbosa, F; Caggiano, J A; DiPuccio, V N; Eckart, M J; Grim, G P; Hartouni, E P; Hatarik, R; Weber, F A
2016-11-01
Sixty-four neutral density filters constructed of metal plates with 88 apertures of varying diameter have been radiographed with a soft x-ray source and CCD camera at National Security Technologies, Livermore. An analysis of the radiographs fits the radial dependence of the apertures' image intensities to sigmoid functions, which can describe the rapidly decreasing intensity towards the apertures' edges. The fitted image intensities determine the relative attenuation value of each filter. Absolute attenuation values of several imaged filters, measured in situ during calibration experiments, normalize the relative quantities which are now used in analyses of neutron spectrometer data at the National Ignition Facility.
Model-based approach to partial tracking for musical transcription
NASA Astrophysics Data System (ADS)
Sterian, Andrew; Wakefield, Gregory H.
1998-10-01
We present a new method for musical partial tracking in the context of musical transcription using a time-frequency Kalman filter structure. The filter is based upon a model for the evolution of a partial behavior across a wide range of pitch from four brass instruments. Statistics are computed independently for the partial attributes of frequency and log-power first differences. We present observed power spectral density shapes, total powers, and histograms, as well as least-squares approximations to these. We demonstrate that a Kalman filter tracker using this partial model is capable of tracking partials in music. We discuss how the filter structure naturally provides quality-of-fit information about the data for use in further processing and how this information can be used to perform partial track initiation and termination within a common framework. We propose that a model-based approach to partial tracking is preferable to existing approaches which generally use heuristic rules or birth/death notions over a small time neighborhood. The advantages include better performance in the presence of cluttered data and simplified tracking over missed observations.
Active Control of Wind Tunnel Noise
NASA Technical Reports Server (NTRS)
Hollis, Patrick (Principal Investigator)
1991-01-01
The need for an adaptive active control system was realized, since a wind tunnel is subjected to variations in air velocity, temperature, air turbulence, and some other factors such as nonlinearity. Among many adaptive algorithms, the Least Mean Squares (LMS) algorithm, which is the simplest one, has been used in an Active Noise Control (ANC) system by some researchers. However, Eriksson's results, Eriksson (1985), showed instability in the ANC system with an ER filter for random noise input. The Restricted Least Squares (RLS) algorithm, although computationally more complex than the LMS algorithm, has better convergence and stability properties. The ANC system in the present work was simulated by using an FIR filter with an RLS algorithm for different inputs and for a number of plant models. Simulation results for the ANC system with acoustic feedback showed better robustness when used with the RLS algorithm than with the LMS algorithm for all types of inputs. Overall attenuation in the frequency domain was better in the case of the RLS adaptive algorithm. Simulation results with a more realistic plant model and an RLS adaptive algorithm showed a slower convergence rate than the case with an acoustic plant as a delay plant. However, the attenuation properties were satisfactory for the simulated system with the modified plant. The effect of filter length on the rate of convergence and attenuation was studied. It was found that the rate of convergence decreases with increase in filter length, whereas the attenuation increases with increase in filter length. The final design of the ANC system was simulated and found to have a reasonable convergence rate and good attenuation properties for an input containing discrete frequencies and random noise.
NASA Technical Reports Server (NTRS)
Woodgate, B. E.
1977-01-01
Multistage diffraction filter consisting of coalined series of pinholes on parallel sheets can be used as nondegradable UV filter. Beam is attenuated as each pinhole diffracts radiation in controlled manner into divergent beam, and following pinhole accepts only small part of that beam.
NASA Astrophysics Data System (ADS)
Ikelle, Luc T.; Osen, Are; Amundsen, Lasse; Shen, Yunqing
2004-12-01
The classical linear solutions to the problem of multiple attenuation, like predictive deconvolution, τ-p filtering, or F-K filtering, are generally fast, stable, and robust compared to non-linear solutions, which are generally either iterative or in the form of a series with an infinite number of terms. These qualities have made the linear solutions more attractive to seismic data-processing practitioners. However, most linear solutions, including predictive deconvolution or F-K filtering, contain severe assumptions about the model of the subsurface and the class of free-surface multiples they can attenuate. These assumptions limit their usefulness. In a recent paper, we described an exception to this assertion for OBS data. We showed in that paper that a linear and non-iterative solution to the problem of attenuating free-surface multiples which is as accurate as iterative non-linear solutions can be constructed for OBS data. We here present a similar linear and non-iterative solution for attenuating free-surface multiples in towed-streamer data. For most practical purposes, this linear solution is as accurate as the non-linear ones.
Comb-based radiofrequency photonic filters with rapid tunability and high selectivity
NASA Astrophysics Data System (ADS)
Supradeepa, V. R.; Long, Christopher M.; Wu, Rui; Ferdous, Fahmida; Hamidi, Ehsan; Leaird, Daniel E.; Weiner, Andrew M.
2012-03-01
Photonic technologies have received considerable attention regarding the enhancement of radiofrequency electrical systems, including high-frequency analogue signal transmission, control of phased arrays, analog-to-digital conversion and signal processing. Although the potential of radiofrequency photonics for the implementation of tunable electrical filters over broad radiofrequency bandwidths has been much discussed, the realization of programmable filters with highly selective filter lineshapes and rapid reconfigurability has faced significant challenges. A new approach for radiofrequency photonic filters based on frequency combs offers a potential route to simultaneous high stopband attenuation, fast tunability and bandwidth reconfiguration. In one configuration, tuning of the radiofrequency passband frequency is demonstrated with unprecedented (~40 ns) speed by controlling the optical delay between combs. In a second, fixed filter configuration, cascaded four-wave mixing simultaneously broadens and smoothes the comb spectra, resulting in Gaussian radiofrequency filter lineshapes exhibiting an extremely high (>60 dB) main lobe to sidelobe suppression ratio and (>70 dB) stopband attenuation.
Jiang, Xiaolei; Zhang, Li; Zhang, Ran; Yin, Hongxia; Wang, Zhenchang
2015-01-01
X-ray grating interferometry offers a novel framework for the study of weakly absorbing samples. Three kinds of information, that is, the attenuation, differential phase contrast (DPC), and dark-field images, can be obtained after a single scanning, providing additional and complementary information to the conventional attenuation image. Phase shifts of X-rays are measured by the DPC method; hence, DPC-CT reconstructs refraction indexes rather than attenuation coefficients. In this work, we propose an explicit filtering based low-dose differential phase reconstruction algorithm, which enables reconstruction from reduced scanning without artifacts. The algorithm adopts a differential algebraic reconstruction technique (DART) with the explicit filtering based sparse regularization rather than the commonly used total variation (TV) method. Both the numerical simulation and the biological sample experiment demonstrate the feasibility of the proposed algorithm.
Zhang, Li; Zhang, Ran; Yin, Hongxia; Wang, Zhenchang
2015-01-01
X-ray grating interferometry offers a novel framework for the study of weakly absorbing samples. Three kinds of information, that is, the attenuation, differential phase contrast (DPC), and dark-field images, can be obtained after a single scanning, providing additional and complementary information to the conventional attenuation image. Phase shifts of X-rays are measured by the DPC method; hence, DPC-CT reconstructs refraction indexes rather than attenuation coefficients. In this work, we propose an explicit filtering based low-dose differential phase reconstruction algorithm, which enables reconstruction from reduced scanning without artifacts. The algorithm adopts a differential algebraic reconstruction technique (DART) with the explicit filtering based sparse regularization rather than the commonly used total variation (TV) method. Both the numerical simulation and the biological sample experiment demonstrate the feasibility of the proposed algorithm. PMID:26089971
IGMtransmission: Transmission curve computation
NASA Astrophysics Data System (ADS)
Harrison, Christopher M.; Meiksin, Avery; Stock, David
2015-04-01
IGMtransmission is a Java graphical user interface that implements Monte Carlo simulations to compute the corrections to colors of high-redshift galaxies due to intergalactic attenuation based on current models of the Intergalactic Medium. The effects of absorption due to neutral hydrogen are considered, with particular attention to the stochastic effects of Lyman Limit Systems. Attenuation curves are produced, as well as colors for a wide range of filter responses and model galaxy spectra. Photometric filters are included for the Hubble Space Telescope, the Keck telescope, the Mt. Palomar 200-inch, the SUBARU telescope and UKIRT; alternative filter response curves and spectra may be readily uploaded.
Wu, Yan; Aarts, Ronald M.
2018-01-01
A recurring problem regarding the use of conventional comb filter approaches for elimination of periodic waveforms is the degree of selectivity achieved by the filtering process. Some applications, such as the gradient artefact correction in EEG recordings during coregistered EEG-fMRI, require a highly selective comb filtering that provides effective attenuation in the stopbands and gain close to unity in the pass-bands. In this paper, we present a novel comb filtering implementation whereby the iterative filtering application of FIR moving average-based approaches is exploited in order to enhance the comb filtering selectivity. Our results indicate that the proposed approach can be used to effectively approximate the FIR moving average filter characteristics to those of an ideal filter. A cascaded implementation using the proposed approach shows to further increase the attenuation in the filter stopbands. Moreover, broadening of the bandwidth of the comb filtering stopbands around −3 dB according to the fundamental frequency of the stopband can be achieved by the novel method, which constitutes an important characteristic to account for broadening of the harmonic gradient artefact spectral lines. In parallel, the proposed filtering implementation can also be used to design a novel notch filtering approach with enhanced selectivity as well. PMID:29599955
77 FR 7523 - Airworthiness Directives; Airbus Airplanes
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-13
... with 2 flow metering systems equipped with upgraded water absorbing filter elements. This AD was prompted by reports of partial blockage of a certain water absorbing filter element. We are issuing this AD to prevent partial blockage of a certain water absorbing filter element, which could lead to...
Technology optimization techniques for multicomponent optical band-pass filter manufacturing
NASA Astrophysics Data System (ADS)
Baranov, Yuri P.; Gryaznov, Georgiy M.; Rodionov, Andrey Y.; Obrezkov, Andrey V.; Medvedev, Roman V.; Chivanov, Alexey N.
2016-04-01
Narrowband optical devices (like IR-sensing devices, celestial navigation systems, solar-blind UV-systems and many others) are one of the most fast-growing areas in optical manufacturing. However, signal strength in this type of applications is quite low and performance of devices depends on attenuation level of wavelengths out of operating range. Modern detectors (photodiodes, matrix detectors, photomultiplier tubes and others) usually do not have required selectivity or have higher sensitivity to background spectrum at worst. Manufacturing of a single component band-pass filter with high attenuation level of wavelength is resource-intensive task. Sometimes it's not possible to find solution for this problem using existing technologies. Different types of filters have technology variations of transmittance profile shape due to various production factors. At the same time there are multiple tasks with strict requirements for background spectrum attenuation in narrowband optical devices. For example, in solar-blind UV-system wavelengths above 290-300 nm must be attenuated by 180dB. In this paper techniques of multi-component optical band-pass filters assembly from multiple single elements with technology variations of transmittance profile shape for optimal signal-tonoise ratio (SNR) were proposed. Relationships between signal-to-noise ratio and different characteristics of transmittance profile shape were shown. Obtained practical results were in rather good agreement with our calculations.
Preliminary Mechanical Characterization of Thermal Filters for the X-IFU Instrument on Athena
NASA Astrophysics Data System (ADS)
Barbera, Marco; Lo Cicero, Ugo; Sciortino, Luisa; Parodi, Giancarlo; D'Anca, Fabio; Giglio, Paolo; Ferruggia Bonura, Salvatore; Nuzzo, Flavio; Jimenez Escobar, Antonio; Ciaravella, Angela; Collura, Alfonso; Varisco, Salvatore; Samain, Valerie
2018-05-01
The X-ray Integral Field Unit (X-IFU) is one of the two instruments of the Athena astrophysics space mission approved by ESA in the Cosmic Vision Science Program. The X-IFU consists of a large array of TES microcalorimeters that will operate at 50 mK inside a sophisticated cryostat. A set of thin filters, highly transparent to X-rays, will be mounted on the cryostat thermal shields in order to attenuate the IR radiative load, to attenuate RF electromagnetic interferences, and to protect the detector from contamination. In this paper, we present the current thermal filters design, describe the filter samples developed/procured so far, and present preliminary results from the ongoing characterization tests.
Stability and performance of notch filter control for unbalance response
NASA Technical Reports Server (NTRS)
Knospe, C. R.
1992-01-01
Many current applications of magnetic bearings for rotating machinery employ notch filters in the feedback control loop to reduce the synchronous forces transmitted through the bearings. The capabilities and limitations of notch filter control are investigated. First, a rigid rotor is examined with some classical root locus techniques. Notch filter control is shown to result in conditional stability whenever complete synchronous attenuation is required. Next, a nondimensional parametric symmetric flexible three mass rotor model is constructed. An examination of this model for several test cases illustrates the limited attenuation possible with notch filters at and near the system critical speeds when the bearing damping is low. The notch filter's alteration of the feedback loop is shown to cause stability problems which limits performance. Poor transient response may also result. A high speed compressor is then examined as a candidate for notch filter control. A collocated 22 mass station model with lead-lag control is used. The analysis confirms the reduction in stability robustness that can occur with notch filter control. It is concluded that other methods of synchronous vibration control yield greater performance without compromising stability.
Adaptive attenuation of aliased ground roll using the shearlet transform
NASA Astrophysics Data System (ADS)
Hosseini, Seyed Abolfazl; Javaherian, Abdolrahim; Hassani, Hossien; Torabi, Siyavash; Sadri, Maryam
2015-01-01
Attenuation of ground roll is an essential step in seismic data processing. Spatial aliasing of the ground roll may cause the overlap of the ground roll with reflections in the f-k domain. The shearlet transform is a directional and multidimensional transform that separates the events with different dips and generates subimages in different scales and directions. In this study, the shearlet transform was used adaptively to attenuate aliased and non-aliased ground roll. After defining a filtering zone, an input shot record is divided into segments. Each segment overlaps adjacent segments. To apply the shearlet transform on each segment, the subimages containing aliased and non-aliased ground roll, the locations of these events on each subimage are selected adaptively. Based on these locations, mute is applied on the selected subimages. The filtered segments are merged together, using the Hanning function, after applying the inverse shearlet transform. This adaptive process of ground roll attenuation was tested on synthetic data, and field shot records from west of Iran. Analysis of the results using the f-k spectra revealed that the non-aliased and most of the aliased ground roll were attenuated using the proposed adaptive attenuation procedure. Also, we applied this method on shot records of a 2D land survey, and the data sets before and after ground roll attenuation were stacked and compared. The stacked section after ground roll attenuation contained less linear ground roll noise and more continuous reflections in comparison with the stacked section before the ground roll attenuation. The proposed method has some drawbacks such as more run time in comparison with traditional methods such as f-k filtering and reduced performance when the dip and frequency content of aliased ground roll are the same as those of the reflections.
Does partial occlusion promote normal binocular function?
Li, Jingrong; Thompson, Benjamin; Ding, Zhaofeng; Chan, Lily Y L; Chen, Xiang; Yu, Minbin; Deng, Daming; Hess, Robert F
2012-10-03
There is growing evidence that abnormal binocular interactions play a key role in the amblyopia syndrome and represent a viable target for treatment interventions. In this context the use of partial occlusion using optical devices such as Bangerter filters as an alternative to complete occlusion is of particular interest. The aims of this study were to understand why Bangerter filters do not result in improved binocular outcomes compared to complete occlusion, and to compare the effects of Bangerter filters, optical blur and neutral density (ND) filters on normal binocular function. The effects of four strengths of Bangerter filters (0.8, 0.6, 0.4, 0.2) on letter and vernier acuity, contrast sensitivity, stereoacuity, and interocular suppression were measured in 21 observers with normal vision. In a subset of 14 observers, the partial occlusion effects of Bangerter filters, ND filters and plus lenses on stereopsis and interocular suppression were compared. Bangerter filters did not have graded effect on vision and induced significant disruption to binocular function. This disruption was greater than that of monocular defocus but weaker than that of ND filters. The effect of the Bangerter filters on stereopsis was more pronounced than their effect on monocular acuity, and the induced monocular acuity deficits did not predict the induced deficits in stereopsis. Bangerter filters appear to be particularly disruptive to binocular function. Other interventions, such as optical defocus and those employing computer generated dichoptic stimulus presentation, may be more appropriate than partial occlusion for targeting binocular function during amblyopia treatment.
Light-attenuating effect of dentin on the polymerization of light-activated restorative resins.
Arikawa, Hiroyuki; Kanie, Takahito; Fujii, Koichi; Ban, Seiji; Takahashi, Hideo
2004-12-01
The light-attenuating effect of dentin on the mechanical properties of light-activated composite resins was evaluated using a simple experimental filter. The filter was designed to simulate the light transmittance and light diffusion characteristics of 1.0-mm thick dentin. The depth of cure, surface hardness, and flexural strength for 13 shades of three light-activated restorative resins were examined. These resins were cured either using direct irradiation with a light source, or indirect irradiation through the filter. The attenuation of light intensity by 1.0-mm thick dentin reached 85-90% in the 400-550 nm wavelength region. For all materials, the values of depth of cure, surface hardness on the top and bottom surfaces, and flexural strength of specimens irradiated indirectly through the simulated 1.0-mm thick dentin filter decreased by 37-60%, 16-55%, 50-83%, and 44-82% in comparison with those by direct irradiation, respectively. Recovery from mechanical properties' reduction was achieved when materials were irradiated 1.5-4 times longer than the standard irradiation time.
Dichroic filters to protect milliwatt far-infrared detectors from megawatt ECRH radiation.
Bertschinger, G; Endres, C P; Lewen, F; Oosterbeek, J W
2008-10-01
Dichroic filters have been used to shield effectively the far infrared (FIR) detectors at the interferometer/polarimeter on TEXTOR. The filters consist of metal foils with regular holes, the hole diameter, the mutual spacing and the thickness of the foils are chosen to transmit radiation at the design frequency with transmission >90%. The attenuation at the low frequency end of the bandpass filter is about 30 dB per octave, the high frequency transmission is between 20% and 40%. The filters have been used to block the stray radiation from the megawatt microwave heating beam to the detectors of the FIR interferometer, operating with power on the detector in the milliwatt range. If required, the low frequency attenuation can be still enhanced, without compromising the transmission in the passband. The FIR interferometer used for plasma density and position control is no longer disturbed by electromagnetic waves used for plasma heating.
Ground roll attenuation using polarization analysis in the t-f-k domain
NASA Astrophysics Data System (ADS)
Wang, C.; Wang, Y.
2017-07-01
S waves travel slower than P waves and have a lower dominant frequency. Therefore, applying common techniques such as time-frequency filtering and f-k filtering to separate S waves from ground roll is difficult because ground roll is also characterized by slow velocity and low frequency. In this study, we present a method for attenuating ground roll using a polarization filtering method based on the t-f-k transform. We describe the particle motion of the waves by complex vector signals. Each pair of frequency components, whose frequencies have the same absolute value but different signs, of the complex signal indicate an elliptical or linear motion. The polarization parameters of the elliptical or linear motion are explicitly related to the two Fourier coefficients. We then extend these concepts to the t-f-k domain and propose a polarization filtering method for ground roll attenuation based on the t-f-k transform. The proposed approach can define automatically the time-varying reject zones on the f-k panel at different times as a function of the reciprocal ellipticity. Four attributes, time, frequency, apparent velocity and polarization are used to identify and extract the ground roll simultaneously. Thus, the ground roll and body waves can be separated as long as they are dissimilar in one of these attributes. We compare our method with commonly used filtering techniques by applying the methods to synthetic and real seismic data. The results indicate that our method can attenuate ground roll while preserving body waves more effectively than the other methods.
NASA Technical Reports Server (NTRS)
Manning, Robert M.
1991-01-01
The dynamic and composite nature of propagation impairments that are incurred on Earth-space communications links at frequencies in and above 30/20 GHz Ka band, i.e., rain attenuation, cloud and/or clear air scintillation, etc., combined with the need to counter such degradations after the small link margins have been exceeded, necessitate the use of dynamic statistical identification and prediction processing of the fading signal in order to optimally estimate and predict the levels of each of the deleterious attenuation components. Such requirements are being met in NASA's Advanced Communications Technology Satellite (ACTS) Project by the implementation of optimal processing schemes derived through the use of the Rain Attenuation Prediction Model and nonlinear Markov filtering theory.
Modeling Contamination Migration on the Chandra X-ray Observatory II
NASA Technical Reports Server (NTRS)
O'Dell, Steve; Swartz, Doug; Tice, Neil; Plucinsky, Paul; Grant, Catherine; Marshall, Herman; Vikhlinin, Alexey
2013-01-01
During its first 14 years of operation, the cold (about -60degC) optical blocking filter of the Advanced CCD Imaging Spectrometer (ACIS), aboard the Chandra X-ray Observatory, has accumulated a growing layer of molecular contamination that attenuates low-energy x rays. Over the past few years, the accumulation rate, spatial distribution, and composition may have changed, perhaps partially related to changes in the operating temperature of the ACIS housing. This evolution of the accumulation of the molecular contamination has motivated further analysis of contamination migration on the Chandra X-ray Observatory, particularly within and near the ACIS cavity. To this end, the current study employs a higher-fidelity geometric model of the ACIS cavity, detailed thermal modeling based upon monitored temperature data, and an accordingly refined model of the molecular transport.
Zhang, Y.; Xu, Y.; Xia, J.
2011-01-01
We analyse dispersion and attenuation of surface waves at free surfaces of possible vacuum/poroelastic media: permeable-'open pore', impermeable-'closed pore' and partially permeable boundaries, which have not been previously reported in detail by researchers, under different surface-permeable, viscous-damping, elastic and fluid-flowing conditions. Our discussion is focused on their characteristics in the exploration-seismic frequency band (a few through 200 Hz) for near-surface applications. We find two surface-wave modes exist, R1 waves for all conditions, and R2 waves for closed-pore and partially permeable conditions. For R1 waves, velocities disperse most under partially permeable conditions and least under the open-pore condition. High-coupling damping coefficients move the main dispersion frequency range to high frequencies. There is an f1 frequency dependence as a constant-Q model for attenuation at high frequencies. R1 waves for the open pore are most sensitive to elastic modulus variation, but least sensitive to tortuosities variation. R1 waves for partially permeable surface radiate as non-physical waves (Im(k) < 0) at low frequencies. For R2 waves, velocities are slightly lower than the bulk slow P2 waves. At low frequencies, both velocity and attenuation are diffusive of f1/2 frequency dependence, as P2 waves. It is found that for partially permeable surfaces, the attenuation displays -f1 frequency dependence as frequency increasing. High surface permeability, low-coupling damping coefficients, low Poisson's ratios, and low tortuosities increase the slope of the -f1 dependence. When the attenuation coefficients reach 0, R2 waves for partially permeable surface begin to radiate as non-physical waves. ?? 2011 The Authors Geophysical Journal International ?? 2011 RAS.
NASA Astrophysics Data System (ADS)
Bu, Xianye; Dong, Hongli; Han, Fei; Li, Gongfa
2018-07-01
This paper is concerned with the distributed filtering problem for a class of time-varying systems subject to deception attacks and event-triggering protocols. Due to the bandwidth limitation, an event-triggered communication strategy is adopted to alleviate the data transmission pressure in the algorithm implementation process. The partial nodes-based filtering problem is considered, where only a partial of nodes can measure the information of the plant. Meanwhile, the measurement information possibly suffers the deception attacks in the transmission process. Sufficient conditions can be established such that the error dynamics satisfies the prescribed average ? performance constraints. The parameters of designed filters can be calculated by solving a series of recursive linear matrix inequalities. A simulation example is presented to demonstrate the effectiveness of the proposed filtering method in this paper.
A high temperature superconductor notch filter for the Sardinia Radio Telescope
NASA Astrophysics Data System (ADS)
Bolli, Pietro; Cresci, Luca; Huang, Frederick; Mariotti, Sergio; Panella, Dario
2018-04-01
A High Temperature Superconductor filter operating in the C-band between 4200 and 5600 MHz has been developed for one of the radio astronomical receivers of the Sardinia Radio Telescope. The motivation was to attenuate an interference from a weather radar at 5640 MHz, whose power level exceeds the linear region of the first active stages of the receiver. A very sharp transition after the nominal maximum passband frequency is reached by combining a 6th order band-pass filter with a 6th order stop-band. This solution is competitive with an alternative layout based on a cascaded triplet filter. Three units of the filter have been measured with two different calibration approaches to investigate pros and cons of each, and data repeatability. The final performance figures of the filters are: ohmic losses of the order of 0.15-0.25 dB, matching better than -15 dB, and -30 dB attenuation at 5640 MHz. Finally, a more accurate model of the connection between external connector and microstrip shows a better agreement between simulations and experimental data.
NASA Astrophysics Data System (ADS)
Kushino, Akihiro; Yamamoto, Yusei; Okuyama, Tetsuya; Kasai, Soichi
We have developed and evaluated thin semi-rigid coaxial cables as the noise filter for readout in low temperature experiments. The cables reported have 0.86 mm outer diameters consisting of seamless outer conductor, polytetrafluoroethylene (PTFE) dielectric, and center conductor made of superconducting niobium-titanium (NbTi). Each center conductor has surficial cladding made of normal conductor in different thickness. We had reported that we can adjust attenuation magnitude and cut-off frequency of the semi-rigid cable in the range about 100 500 MHz by controlling cable length and/or thickness of cladding. We newly manufactured this type of low-pass filter cables using stainless-steel (SUS304) as the material for cladding which has higher electrical resistivity than that of cupro-nickel (CuNi). It enables high filtering efficiency, i.e. large attenuation at the same frequency, compared to those made of conventional CuNi-based low-pass-filter cables.
Knapp, R.W.; Anderson, N.L.
1994-01-01
Data may be overprinted by a steady-state cyclical noise (hum). Steady-state indicates that the noise is invariant with time; its attributes, frequency, amplitude, and phase, do not change with time. Hum recorded on seismic data usually is powerline noise and associated higher harmonics; leakage from full-waveform rectified cathodic protection devices that contain the odd higher harmonics of powerline frequencies; or vibrational noise from mechanical devices. The fundamental frequency of powerline hum may be removed during data acquisition with the use of notch filters. Unfortunately, notch filters do not discriminate signal and noise, attenuating both. They also distort adjacent frequencies by phase shifting. Finally, they attenuate only the fundamental mode of the powerline noise; higher harmonics and frequencies other than that of powerlines are not removed. Digital notch filters, applied during processing, have many of the same problems as analog filters applied in the field. The method described here removes hum of a particular frequency. Hum attributes are measured by discrete Fourier analysis, and the hum is canceled from the data by subtraction. Errors are slight and the result of the presence of (random) noise in the window or asynchrony of the hum and data sampling. Error is minimized by increasing window size or by resampling to a finer interval. Errors affect the degree of hum attenuation, not the signal. The residual is steady-state hum of the same frequency. ?? 1994.
Höckel, David; Koch, Lars; Martin, Eugen; Benson, Oliver
2009-10-15
We describe a Fabry-Perot-based spectral filter for free-space quantum key distribution (QKD). A multipass etalon filter was built, and its performance was studied. The whole filter setup was carefully optimized to add less than 2 dB attenuation to a signal beam but block stray light by 21 dB. Simulations show that such a filter might be sufficient to allow QKD satellite downlinks during daytime with the current technology.
Sturesson, Louise W; Frennström, Jan O; Ilardi, Marcella; Reinstrup, Peter
2015-08-01
A modified heat-moisture exchanger that incorporates a reflecting filter for use with partial rebreathing of exhaled volatile anaesthetics has been commercially available since the 1990 s. The main advantages of the device are efficient delivery of inhaled sedation to intensive care patients and reduced anaesthetic consumption during anaesthesia. However, elevated arterial CO2 values have been observed with an anaesthetic conserving device compared with a conventional heat and moisture exchanger, despite compensation for larger apparatus dead space. The objective of this study is to thoroughly explore the properties of two reflecting materials (charcoal and zeolites). A controlled, prospective, observational laboratory study. Lund University Hospital, Sweden, from December 2011 to December 2012. None. Three filters, with identical volumes, were compared using different volatile anaesthetics at different conditions of temperature and moisture. The filtering materials were charcoal or zeolite. Glass spheres were used as an inert control. Consumption of volatile anaesthetics using different reflecting materials in filters at different conditions regarding temperature and moisture. CO2 reflection by the filtering materials: glass spheres, charcoal or zeolite. Isoflurane consumption in an open system was 60.8 g h(-1). The isoflurane consumption in dry, warm air was 39.8 g h(-1) with glass spheres. Changing to charcoal and zeolite had a profound effect on isoflurane consumption, 11.8 and 10.7 g h(-1), respectively. Heating and humidifying the air as well as the addition of N2O created only minor changes in consumption. The percentage of isoflurane conserved by the charcoal filter was independent of the isoflurane concentration (0.5 to 4.5%). Reflection of sevoflurane, desflurane and halothane by the charcoal filter was similar to reflection of isoflurane. Both charcoal and zeolite filters had CO2 reflecting properties and end-tidal CO2 increased by 3 to 3.7% compared with glass spheres. This increase was attenuated to 1 to 1.4% when the air was heated and humidified, and isoflurane was added. Charcoal and zeolite possess gas-reflecting properties, which can be used to conserve volatile anaesthetics. They also reflect CO2. The degree of CO2 reflection was reduced by heating and humidifying the air.
Bowtie filters for dedicated breast CT: Theory and computational implementation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kontson, Kimberly, E-mail: Kimberly.Kontson@fda.hhs.gov; Jennings, Robert J.
Purpose: To design bowtie filters with improved properties for dedicated breast CT to improve image quality and reduce dose to the patient. Methods: The authors present three different bowtie filters designed for a cylindrical 14-cm diameter phantom with a uniform composition of 40/60 breast tissue, which vary in their design objectives and performance improvements. Bowtie design #1 is based on single material spectral matching and produces nearly uniform spectral shape for radiation incident upon the detector. Bowtie design #2 uses the idea of basis material decomposition to produce the same spectral shape and intensity at the detector, using two differentmore » materials. Bowtie design #3 eliminates the beam hardening effect in the reconstructed image by adjusting the bowtie filter thickness so that the effective attenuation coefficient for every ray is the same. All three designs are obtained using analytical computational methods and linear attenuation coefficients. Thus, the designs do not take into account the effects of scatter. The authors considered this to be a reasonable approach to the filter design problem since the use of Monte Carlo methods would have been computationally intensive. The filter profiles for a cone-angle of 0° were used for the entire length of each filter because the differences between those profiles and the correct cone-beam profiles for the cone angles in our system are very small, and the constant profiles allowed construction of the filters with the facilities available to us. For evaluation of the filters, we used Monte Carlo simulation techniques and the full cone-beam geometry. Images were generated with and without each bowtie filter to analyze the effect on dose distribution, noise uniformity, and contrast-to-noise ratio (CNR) homogeneity. Line profiles through the reconstructed images generated from the simulated projection images were also used as validation for the filter designs. Results: Examples of the three designs are presented. Initial verification of performance of the designs was done using analytical computations of HVL, intensity, and effective attenuation coefficient behind the phantom as a function of fan-angle with a cone-angle of 0°. The performance of the designs depends only weakly on incident spectrum and tissue composition. For all designs, the dynamic range requirement on the detector was reduced compared to the no-bowtie-filter case. Further verification of the filter designs was achieved through analysis of reconstructed images from simulations. Simulation data also showed that the use of our bowtie filters can reduce peripheral dose to the breast by 61% and provide uniform noise and CNR distributions. The bowtie filter design concepts validated in this work were then used to create a computational realization of a 3D anthropomorphic bowtie filter capable of achieving a constant effective attenuation coefficient behind the entire field-of-view of an anthropomorphic breast phantom. Conclusions: Three different bowtie filter designs that vary in performance improvements were described and evaluated using computational and simulation techniques. Results indicate that the designs are robust against variations in breast diameter, breast composition, and tube voltage, and that the use of these filters can reduce patient dose and improve image quality compared to the no-bowtie-filter case.« less
ANTIANDROGENIC EFFECTS OF VINCLOZOLIN ON MALE RATS ARE PARTIALLY ATTENUATED BY TESTOSTERONE PROPIONATE
Cynthia Wolf1,2 , Joe Ostby1, Jonathan Furr 1, Gerald A. LeBlanc2, and L. Earl Gray, Jr.1
1 US Environmental Protection Agency, NHEERL, RTD, RTP, NC 27711, 2 Departmen...
MASCULINIZATION OF FEMALE RATS BY PRENATAL TESTOSTERONE PROPIONATE IS PARTIALLY ATTENUATED BY VINCLOZOLIN
Cynthia Wolf1,2, Gerald LeBlanc2, Andrew Hotchkiss3, Jonathan Furr1, L Earl Gray, Jr.1
1USEPA, Reproductive Toxicology Division, RTP, NC 27711, 2Dept. Molecular and En...
Tivers, M S; House, A K; Smith, K C; Wheeler-Jones, C P D; Lipscomb, V J
2014-01-01
Dogs with congenital portosystemic shunts (CPSS) have hypoplasia of the intrahepatic portal veins. Surgical CPSS attenuation results in the development of the intrahepatic portal vasculature, the precise mechanism for which is unknown, although new vessel formation by angiogenesis is suspected. That the degree of portal vascular development and the increase in portal vascularization after CPSS attenuation is significantly associated with hepatic vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR2) gene expression and serum VEGF concentration. Client-owned dogs with CPSS undergoing surgical treatment. Forty-nine dogs were included in the gene expression data and 35 in the serum VEGF data. Dogs surgically treated by partial or complete CPSS attenuation were prospectively recruited. Relative gene expression of VEGF and VEGFR2 was measured in liver biopsy samples taken at initial and follow-up surgery using quantitative polymerase chain reaction. Serum VEGF concentration was measured before and after CPSS attenuation using a canine specific ELISA. Statistical significance was set at the 5% level (P ≤ .05). There was a significant increase in the mRNA expression of VEGFR2 after partial attenuation (P = .006). Dogs that could tolerate complete attenuation had significantly greater VEGFR2 mRNA expression than those that only tolerated partial attenuation (P = .037). Serum VEGF concentration was significantly increased at 24 (P < .001) and 48 (P = .003) hours after attenuation. These findings suggest that intrahepatic angiogenesis is likely to occur after the surgical attenuation of CPSS in dogs, and contributes to the development of the intrahepatic vasculature postoperatively. Copyright © 2014 by the American College of Veterinary Internal Medicine.
Modern Display Technologies for Airborne Applications.
1983-04-01
the case of LED head-down direct view displays, this requires that special attention be paid to the optical filtering , the electrical drive/address...effectively attenuates the LED specular reflectance component, the colour and neutral density filtering attentuate the diffuse component and the... filter techniques are planned for use with video, multi- colour and advanced versions of numeric, alphanumeric and graphic displays; this technique
Van Delden, Jay S
2003-07-15
A novel, interferometric, polarization-interrogating filter assembly and method for the simultaneous measurement of all four Stokes parameters across a partially polarized irradiance image in a no-moving-parts, instantaneous, highly sensitive manner is described. In the reported embodiment of the filter, two spatially varying linear retarders and a linear polarizer comprise an ortho-Babinet, polarization-interrogating (OBPI) filter. The OBPI filter uniquely encodes the incident ensemble of electromagnetic wave fronts comprising a partially polarized irradiance image in a controlled, deterministic, spatially varying manner to map the complete state of polarization across the image to local variations in a superposed interference pattern. Experimental interferograms are reported along with a numerical simulation of the method.
Developing a Short-Period, Fundamental-Mode Rayleigh-Wave Attenuation Model for Asia
NASA Astrophysics Data System (ADS)
Yang, X.; Levshin, A. L.; Barmin, M. P.; Ritzwoller, M. H.
2008-12-01
We are developing a 2D, short-period (12 - 22 s), fundamental-mode Rayleigh-wave attenuation model for Asia. This model can be used to invert for a 3D attenuation model of the Earth's crust and upper mantle as well as to implement more accurate path corrections in regional surface-wave magnitude calculations. The prerequisite for developing a reliable Rayleigh-wave attenuation model is the availability of accurate fundamental-mode Rayleigh-wave amplitude measurements. Fundamental-mode Rayleigh-wave amplitudes could be contaminated by a variety of sources such as multipathing, focusing and defocusing, body wave, higher-mode surface wave, and other noise sources. These contaminations must be reduced to the largest extent possible. To achieve this, we designed a procedure by taking advantage of certain Rayleigh-wave characteristics, such as dispersion and elliptical particle motion, for accurate amplitude measurements. We first analyze the dispersion of the surface-wave data using a spectrogram. Based on the characteristics of the data dispersion, we design a phase-matched filter by using either a manually picked dispersion curve, or a group-velocity-model predicted dispersion curve, or the dispersion of the data, and apply the filter to the seismogram. Intelligent filtering of the seismogram and windowing of the resulting cross-correlation based on the spectrogram analysis and the comparison between the phase-match filtered data spectrum, the raw-data spectrum and the theoretical source spectrum effectively reduces amplitude contaminations and results in reliable amplitude measurements in many cases. We implemented these measuring techniques in a graphic-user-interface tool called Surface Wave Amplitude Measurement Tool (SWAMTOOL). Using the tool, we collected and processed waveform data for 200 earthquakes occurring throughout 2003-2006 inside and around Eurasia. The records from 135 broadband stations were used. After obtaining the Rayleigh-wave amplitude measurements, we analyzed the attenuation behavior of the amplitudes using source- and receiver-specific terms calculated from a 3D velocity model of the region. Based on the results, we removed amplitudes that yielded negative average attenuation coefficients, and included an additional parameter in the inversion to account for the possible bias of the CMT moments. Using the high-quality amplitude measurements in a tomographic inversion, we obtained a fundamental-mode Rayleigh-wave attenuation- coefficient model for periods between 12 and 22 s for Asia and surrounding regions. The inverted attenuation model is consistent with the geological features of Asia. We observe low attenuation in stable regions such as eastern Europe, the Siberian platforms, the Indian shield, the Arabian platform, the Yangtze craton, and others. High attenuation is observed in tectonically active regions such as the Himalayas, the Tian Shan, Pamir and Zagros mountains.
2017-04-01
complementary fusion: Fourth-order Butterworth filter was used to high -pass ocelli and low-pass optic flow. The normalized cutoff frequency had to be kept...information introduced by luminance change. The high - frequency cutoff was added to reject the flickering noise for indoor usage. The filtered signals from the...function of the low- pass filter is to attenuate high - frequency noise. The final band-pass filter transfer function is in Eq. 2. (()
NASA Astrophysics Data System (ADS)
Fayadh, Rashid A.; Malek, F.; Fadhil, Hilal A.; Aldhaibani, Jaafar A.; Salman, M. K.; Abdullah, Farah Salwani
2015-05-01
For high data rate propagation in wireless ultra-wideband (UWB) communication systems, the inter-symbol interference (ISI), multiple-access interference (MAI), and multiple-users interference (MUI) are influencing the performance of the wireless systems. In this paper, the rake-receiver was presented with the spread signal by direct sequence spread spectrum (DS-SS) technique. The adaptive rake-receiver structure was shown with adjusting the receiver tap weights using least mean squares (LMS), normalized least mean squares (NLMS), and affine projection algorithms (APA) to support the weak signals by noise cancellation and mitigate the interferences. To minimize the data convergence speed and to reduce the computational complexity by the previous algorithms, a well-known approach of partial-updates (PU) adaptive filters were employed with algorithms, such as sequential-partial, periodic-partial, M-max-partial, and selective-partial updates (SPU) in the proposed system. The simulation results of bit error rate (BER) versus signal-to-noise ratio (SNR) are illustrated to show the performance of partial-update algorithms that have nearly comparable performance with the full update adaptive filters. Furthermore, the SPU-partial has closed performance to the full-NLMS and full-APA while the M-max-partial has closed performance to the full-LMS updates algorithms.
Removing tidal-period variations from time-series data using low-pass digital filters
Walters, Roy A.; Heston, Cynthia
1982-01-01
Several low-pass, digital filters are examined for their ability to remove tidal Period Variations from a time-series of water surface elevation for San Francisco Bay. The most efficient filter is the one which is applied to the Fourier coefficients of the transformed data, and the filtered data recovered through an inverse transform. The ability of the filters to remove the tidal components increased in the following order: 1) cosine-Lanczos filter, 2) cosine-Lanczos squared filter; 3) Godin filter; and 4) a transform fitter. The Godin fitter is not sufficiently sharp to prevent severe attenuation of 2–3 day variations in surface elevation resulting from weather events.
Pham, Quang Duc; Kusumi, Yuichi; Hasegawa, Satoshi; Hayasaki, Yoshio
2012-10-01
We propose a new method for three-dimensional (3D) position measurement of nanoparticles using an in-line digital holographic microscope. The method improves the signal-to-noise ratio of the amplitude of the interference fringes to achieve higher accuracy in the position measurement by increasing weak scattered light from a nanoparticle relative to the reference light by using a low spatial frequency attenuation filter. We demonstrated the improvements of signal-to-noise ratio of the optical system and contrast of the interference fringes, allowing the 3D positions of nanoparticles to be determined more precisely.
NASA Astrophysics Data System (ADS)
Sixdenier, Fabien; Yade, Ousseynou; Martin, Christian; Bréard, Arnaud; Vollaire, Christian
2018-05-01
Electromagnetic interference (EMI) filters design is a rather difficult task where engineers have to choose adequate magnetic materials, design the magnetic circuit and choose the size and number of turns. The final design must achieve the attenuation requirements (constraints) and has to be as compact as possible (goal). Alternating current (AC) analysis is a powerful tool to predict global impedance or attenuation of any filter. However, AC analysis are generally performed without taking into account the frequency-dependent complex permeability behaviour of soft magnetic materials. That's why, we developed two frequency-dependent complex permeability models able to be included into SPICE models. After an identification process, the performances of each model are compared to measurements made on a realistic EMI filter prototype in common mode (CM) and differential mode (DM) to see the benefit of the approach. Simulation results are in good agreement with the measured ones especially in the middle frequency range.
Research on interpolation methods in medical image processing.
Pan, Mei-Sen; Yang, Xiao-Li; Tang, Jing-Tian
2012-04-01
Image interpolation is widely used for the field of medical image processing. In this paper, interpolation methods are divided into three groups: filter interpolation, ordinary interpolation and general partial volume interpolation. Some commonly-used filter methods for image interpolation are pioneered, but the interpolation effects need to be further improved. When analyzing and discussing ordinary interpolation, many asymmetrical kernel interpolation methods are proposed. Compared with symmetrical kernel ones, the former are have some advantages. After analyzing the partial volume and generalized partial volume estimation interpolations, the new concept and constraint conditions of the general partial volume interpolation are defined, and several new partial volume interpolation functions are derived. By performing the experiments of image scaling, rotation and self-registration, the interpolation methods mentioned in this paper are compared in the entropy, peak signal-to-noise ratio, cross entropy, normalized cross-correlation coefficient and running time. Among the filter interpolation methods, the median and B-spline filter interpolations have a relatively better interpolating performance. Among the ordinary interpolation methods, on the whole, the symmetrical cubic kernel interpolations demonstrate a strong advantage, especially the symmetrical cubic B-spline interpolation. However, we have to mention that they are very time-consuming and have lower time efficiency. As for the general partial volume interpolation methods, from the total error of image self-registration, the symmetrical interpolations provide certain superiority; but considering the processing efficiency, the asymmetrical interpolations are better.
Tivers, Michael S; Lipscomb, Victoria J; Smith, Kenneth C; Wheeler-Jones, Caroline P D; House, Arthur K
2014-05-01
Dogs with congenital portosystemic shunts (CPSS) have liver hypoplasia and hepatic insufficiency. Surgical CPSS attenuation results in liver growth associated with clinical improvement. The mechanism of this hepatic response is unknown, although liver regeneration is suspected. This study investigated whether markers of liver regeneration were associated with CPSS attenuation. Dogs treated with CPSS attenuation were prospectively recruited. Residual liver tissue was collected for gene expression analysis (seven genes) from 24 CPSS dogs that tolerated complete attenuation, 25 dogs that tolerated partial attenuation and seven control dogs. Relative gene expression was measured using quantitative polymerase chain reaction (qPCR). Blood samples were collected before, 24 h and 48 h post-surgery from 36 CPSS dogs and from 10 control dogs. Serum hepatocyte growth factor (HGF) concentration was measured using a canine specific enzyme-linked immunosorbent assay (ELISA). HGF mRNA expression was significantly decreased in CPSS compared with control dogs (P = 0.046). There were significant increases in HGF (P = 0.050) and methionine adenosyltransferase 2 A (MAT2A; P = 0.002) mRNA expression following partial CPSS attenuation. Dogs with complete attenuation had significantly greater MAT2A (P = 0.024) mRNA expression compared with dogs with partial attenuation. Serum HGF concentration significantly increased 24 h following CPSS attenuation (P < 0.001). Hepatic mRNA expression of two markers of hepatocyte proliferation (HGF and MAT2A) was associated with the response to surgery in dogs with CPSS, and serum HGF significantly increased following surgery, suggesting hepatocyte proliferation. These findings support the concept that hepatic regeneration is important in the hepatic response to CPSS surgery. Copyright © 2014 Elsevier Ltd. All rights reserved.
NASA Technical Reports Server (NTRS)
Title, A. M. (Inventor)
1978-01-01
A birefringent filter module comprises, in seriatum. (1) an entrance polarizer, (2) a first birefringent crystal responsive to optical energy exiting the entrance polarizer, (3) a partial polarizer responsive to optical energy exiting the first polarizer, (4) a second birefringent crystal responsive to optical energy exiting the partial polarizer, and (5) an exit polarizer. The first and second birefringent crystals have fast axes disposed + or -45 deg from the high transmitivity direction of the partial polarizer. Preferably, the second crystal has a length 1/2 that of the first crystal and the high transmitivity direction of the partial polarizer is nine times as great as the low transmitivity direction. To provide tuning, the polarizations of the energy entering the first crystal and leaving the second crystal are varied by either rotating the entrance and exit polarizers, or by sandwiching the entrance and exit polarizers between pairs of half wave plates that are rotated relative to the polarizers. A plurality of the filter modules may be cascaded.
Improved estimates of partial volume coefficients from noisy brain MRI using spatial context.
Manjón, José V; Tohka, Jussi; Robles, Montserrat
2010-11-01
This paper addresses the problem of accurate voxel-level estimation of tissue proportions in the human brain magnetic resonance imaging (MRI). Due to the finite resolution of acquisition systems, MRI voxels can contain contributions from more than a single tissue type. The voxel-level estimation of this fractional content is known as partial volume coefficient estimation. In the present work, two new methods to calculate the partial volume coefficients under noisy conditions are introduced and compared with current similar methods. Concretely, a novel Markov Random Field model allowing sharp transitions between partial volume coefficients of neighbouring voxels and an advanced non-local means filtering technique are proposed to reduce the errors due to random noise in the partial volume coefficient estimation. In addition, a comparison was made to find out how the different methodologies affect the measurement of the brain tissue type volumes. Based on the obtained results, the main conclusions are that (1) both Markov Random Field modelling and non-local means filtering improved the partial volume coefficient estimation results, and (2) non-local means filtering was the better of the two strategies for partial volume coefficient estimation. Copyright 2010 Elsevier Inc. All rights reserved.
Shah, Siddharth; Acholonu, Rhonda Graves; Ohene-Frempong, Kwaku; Asakura, Toshio
2015-12-01
We previously found that blood samples collected from steady-state patients with sickle cell disease (SCD) without exposure to air contain a new type of reversibly sickled cells (RSCs) with blunt edges at a level of as high as 78%. Since partial oxygenation of once-deoxygenated sickled cells with pointy edges to near venous oxygen pressure generates similar sickled cells with blunt edges in vitro, we named them as partially oxygenated sickled cells (POSCs). On the other hand, partial deoxygenation of once-oxygenated SS cells to venous oxygen pressure generates partially deoxygenated sickled cells (PDSCs) with pointy edges. In this study, we obtained blood samples from 6 steady-state patients with SCD under venous oxygen pressure without exposure to air, subjected them to various oxygenation/deoxygenation/reoxygenation cycles, and studied their filterability through a membrane filter with pore diameter of 3μm, the theoretical minimum diameter of a capillary. Our results indicated that discocytes, POSCs with blunt edges, and irreversibly sickled cells could deform and pass through the filter, while PDSCs with pointy edges were rigid and could not. The filterability of SS cells seems to be related to the length and amount of deoxy-hemoglobin S fibers in the cells. Copyright © 2015. Published by Elsevier Inc.
Xu, Wenjun; Tang, Chen; Gu, Fan; Cheng, Jiajia
2017-04-01
It is a key step to remove the massive speckle noise in electronic speckle pattern interferometry (ESPI) fringe patterns. In the spatial-domain filtering methods, oriented partial differential equations have been demonstrated to be a powerful tool. In the transform-domain filtering methods, the shearlet transform is a state-of-the-art method. In this paper, we propose a filtering method for ESPI fringe patterns denoising, which is a combination of second-order oriented partial differential equation (SOOPDE) and the shearlet transform, named SOOPDE-Shearlet. Here, the shearlet transform is introduced into the ESPI fringe patterns denoising for the first time. This combination takes advantage of the fact that the spatial-domain filtering method SOOPDE and the transform-domain filtering method shearlet transform benefit from each other. We test the proposed SOOPDE-Shearlet on five experimentally obtained ESPI fringe patterns with poor quality and compare our method with SOOPDE, shearlet transform, windowed Fourier filtering (WFF), and coherence-enhancing diffusion (CEDPDE). Among them, WFF and CEDPDE are the state-of-the-art methods for ESPI fringe patterns denoising in transform domain and spatial domain, respectively. The experimental results have demonstrated the good performance of the proposed SOOPDE-Shearlet.
Dynamics of nonlinear feedback control.
Snippe, H P; van Hateren, J H
2007-05-01
Feedback control in neural systems is ubiquitous. Here we study the mathematics of nonlinear feedback control. We compare models in which the input is multiplied by a dynamic gain (multiplicative control) with models in which the input is divided by a dynamic attenuation (divisive control). The gain signal (resp. the attenuation signal) is obtained through a concatenation of an instantaneous nonlinearity and a linear low-pass filter operating on the output of the feedback loop. For input steps, the dynamics of gain and attenuation can be very different, depending on the mathematical form of the nonlinearity and the ordering of the nonlinearity and the filtering in the feedback loop. Further, the dynamics of feedback control can be strongly asymmetrical for increment versus decrement steps of the input. Nevertheless, for each of the models studied, the nonlinearity in the feedback loop can be chosen such that immediately after an input step, the dynamics of feedback control is symmetric with respect to increments versus decrements. Finally, we study the dynamics of the output of the control loops and find conditions under which overshoots and undershoots of the output relative to the steady-state output occur when the models are stimulated with low-pass filtered steps. For small steps at the input, overshoots and undershoots of the output do not occur when the filtering in the control path is faster than the low-pass filtering at the input. For large steps at the input, however, results depend on the model, and for some of the models, multiple overshoots and undershoots can occur even with a fast control path.
Modulation of Radio Frequency Signals by Nonlinearly Generated Acoustic Fields
2014-01-01
roll -off in attenuation, known as the filter skirt. Therefore, the use of filters can be inadequate if the small signals are close in frequency to the...effect can be avoided by introducing filters into the nonlinear measurement system that have much smaller bandwidths, capable of isolating narrow...contribution from each source of modulation has not been done as isolating each effect during measurement is currently infeasible. To better
The Johnson Matthey PCRT2 1000, v.2 system is a partial continuously regenerating technology (PCRT) system that consists of a flow-through partial filter combined with a DOC. The system is designed for low temperature exhaust resulting from intermittent loads from medium and heav...
Shielded multi-stage EMI noise filter
Kisner, Roger Allen; Fugate, David Lee
2016-11-08
Electromagnetic interference (EMI) noise filter embodiments and methods for filtering are provided herein. EMI noise filters include multiple signal exclusion enclosures. The multiple signal exclusion enclosures contain filter circuit stages. The signal exclusion enclosures can attenuate noise generated external to the enclosures and/or isolate noise currents generated by the corresponding filter circuits within the enclosures. In certain embodiments, an output of one filter circuit stage is connected to an input of the next filter circuit stage. The multiple signal exclusion enclosures can be chambers formed using conductive partitions to divide an outer signal exclusion enclosure. EMI noise filters can also include mechanisms to maintain the components of the filter circuit stages at a consistent temperature. For example, a metal base plate can distribute heat among filter components, and an insulating material can be positioned inside signal exclusion enclosures.
Eliseyev, Andrey; Aksenova, Tetiana
2016-01-01
In the current paper the decoding algorithms for motor-related BCI systems for continuous upper limb trajectory prediction are considered. Two methods for the smooth prediction, namely Sobolev and Polynomial Penalized Multi-Way Partial Least Squares (PLS) regressions, are proposed. The methods are compared to the Multi-Way Partial Least Squares and Kalman Filter approaches. The comparison demonstrated that the proposed methods combined the prediction accuracy of the algorithms of the PLS family and trajectory smoothness of the Kalman Filter. In addition, the prediction delay is significantly lower for the proposed algorithms than for the Kalman Filter approach. The proposed methods could be applied in a wide range of applications beyond neuroscience. PMID:27196417
Generation of Plausible Hurricane Tracks for Preparedness Exercises
2017-04-25
wind extents are simulated by Poisson regression and temporal filtering . The un-optimized MATLAB code runs in less than a minute and is integrated into...of real hurricanes. After wind radii have been simulated for the entire track, median filtering , attenuation over land, and smoothing clean up the wind
Suzuki, Shigeru; Machida, Haruhiko; Tanaka, Isao; Ueno, Eiko
2012-11-01
To compare the performance of model-based iterative reconstruction (MBIR) with that of standard filtered back projection (FBP) for measuring vascular wall attenuation. After subjecting 9 vascular models (actual attenuation value of wall, 89 HU) with wall thickness of 0.5, 1.0, or 1.5 mm that we filled with contrast material of 275, 396, or 542 HU to scanning using 64-detector computed tomography (CT), we reconstructed images using MBIR and FBP (Bone, Detail kernels) and measured wall attenuation at the center of the wall for each model. We performed attenuation measurements for each model and additional supportive measurements by a differentiation curve. We analyzed statistics using analyzes of variance with repeated measures. Using the Bone kernel, standard deviation of the measurement exceeded 30 HU in most conditions. In measurements at the wall center, the attenuation values obtained using MBIR were comparable to or significantly closer to the actual wall attenuation than those acquired using Detail kernel. Using differentiation curves, we could measure attenuation for models with walls of 1.0- or 1.5-mm thickness using MBIR but only those of 1.5-mm thickness using Detail kernel. We detected no significant differences among the attenuation values of the vascular walls of either thickness (MBIR, P=0.1606) or among the 3 densities of intravascular contrast material (MBIR, P=0.8185; Detail kernel, P=0.0802). Compared with FBP, MBIR reduces both reconstruction blur and image noise simultaneously, facilitates recognition of vascular wall boundaries, and can improve accuracy in measuring wall attenuation. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Research on spectroscopic imaging. Volume 1: Technical discussion. [birefringent filters
NASA Technical Reports Server (NTRS)
Title, A.; Rosenberg, W.
1979-01-01
The principals of operation and the capabilities of birefringent filters systems are examined. Topics covered include: Lyot, Solc, and partial polarizer filters; transmission profile management; tuning birefringent filters; field of view; bandpass control; engineering considerations; and recommendations. Improvements for field of view effects, and the development of birefringent filters for spaceflight are discussed in appendices.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vijayan, S; Xiong, Z; Rudin, S
Purpose: The functionality of the Dose-Tracking System (DTS) has been expanded to include the calculation of the Kerma-Area Product (KAP) for non-uniform x-ray fields such as result from the use of compensation filters during fluoroscopic procedures Methods: The DTS calculates skin dose during fluoroscopic interventions and provides a color-coded dose map on a patient-graphic model. The KAP is the integral of air kerma over the x-ray field and is usually measured with a transmission-ionization chamber that intercepts the entire x-ray beam. The DTS has been modified to determine KAP when there are beam non-uniformities that can be modeled. For example,more » the DTS includes models of the three compensation filters with tapered edges located in the collimator assembly of the Toshiba Infinix fluoroscopic C-Arm and can track their movement. To determine the air kerma after the filters, DTS includes transmission factors for the compensation filters as a function of kVp and beam filtration. A virtual KAP dosimeter is simulated in the DTS by an array of graphic vertices; the air kerma at each vertex is corrected by the field non-uniformity, which in this case is the attenuation factor for those rays which pass through the filter. The products of individual vertex air-kerma values for all vertices within the beam times the effective-area-per-vertex are summed for each x-ray pulse to yield the KAP per pulse and the cumulative KAP for the procedure is then calculated. Results: The KAP values estimated by DTS with the compensation filter inserted into the x-ray field agree within ± 6% with the values displayed on the fluoroscopy unit monitor, which are measured with a transmission chamber. Conclusion: The DTS can account for field non-uniformities such as result from the use of compensation filters in calculating KAP and can obviate the need for a KAP transmission ionization chamber. Partial support from NIH Grant R01-EB002873 and Toshiba Medical Systems Corp.« less
Simple and Efficient Single Photon Filter for a Rb-based Quantum Memory
NASA Astrophysics Data System (ADS)
Stack, Daniel; Li, Xiao; Quraishi, Qudsia
2015-05-01
Distribution of entangled quantum states over significant distances is important to the development of future quantum technologies such as long-distance cryptography, networks of atomic clocks, distributed quantum computing, etc. Long-lived quantum memories and single photons are building blocks for systems capable of realizing such applications. The ability to store and retrieve quantum information while filtering unwanted light signals is critical to the operation of quantum memories based on neutral-atom ensembles. We report on an efficient frequency filter which uses a glass cell filled with 85Rb vapor to attenuate noise photons by an order of magnitude with little loss to the single photons associated with the operation of our cold 87Rb quantum memory. An Ar buffer gas is required to differentiate between signal and noise photons or similar statement. Our simple, passive filter requires no optical pumping or external frequency references and provides an additional 18 dB attenuation of our pump laser for every 1 dB loss of the single photon signal. We observe improved non-classical correlations and our data shows that the addition of a frequency filter increases the non-classical correlations and readout efficiency of our quantum memory by ~ 35%.
Brunenders: a partially attenuated historic poliovirus type I vaccine strain.
Sanders, Barbara P; Liu, Ying; Brandjes, Alies; van Hoek, Vladimir; de Los Rios Oakes, Isabel; Lewis, John; Wimmer, Eckard; Custers, Jerome H H V; Schuitemaker, Hanneke; Cello, Jeronimo; Edo-Matas, Diana
2015-09-01
Brunenders, a type I poliovirus (PV) strain, was developed in 1952 by J. F. Enders and colleagues through serial in vitro passaging of the parental Brunhilde strain, and was reported to display partial neuroattenuation in monkeys. This phenotype of attenuation encouraged two vaccine manufacturers to adopt Brunenders as the type I component for their inactivated poliovirus vaccines (IPVs) in the 1950s, although today no licensed IPV vaccine contains Brunenders. Here we confirmed, in a transgenic mouse model, the report of Enders on the reduced neurovirulence of Brunenders. Although dramatically neuroattenuated relative to WT PV strains, Brunenders remains more virulent than the attenuated oral vaccine strain, Sabin 1. Importantly, the neuroattenuation of Brunenders does not affect in vitro growth kinetics and in vitro antigenicity, which were similar to those of Mahoney, the conventional type I IPV vaccine strain. We showed, by full nucleotide sequencing, that Brunhilde and Brunenders differ at 31 nucleotides, eight of which lead to amino acid changes, all located in the capsid. Upon exchanging the Brunenders capsid sequence with that of the Mahoney capsid, WT neurovirulence was regained in vivo, suggesting a role for the capsid mutations in Brunenders attenuation. To date, as polio eradication draws closer, the switch to using attenuated strains for IPV is actively being pursued. Brunenders preceded this novel strategy as a partially attenuated IPV strain, accompanied by decades of successful use in the field. Providing data on the attenuation of Brunenders may be of value in the further construction of attenuated PV strains to support the grand pursuit of the global eradication of poliomyelitis.
Near-source attenuation of high-frequency body waves beneath the New Madrid Seismic Zone
NASA Astrophysics Data System (ADS)
Pezeshk, Shahram; Sedaghati, Farhad; Nazemi, Nima
2018-03-01
Attenuation characteristics in the New Madrid Seismic Zone (NMSZ) are estimated from 157 local seismograph recordings out of 46 earthquakes of 2.6 ≤ M ≤ 4.1 with hypocentral distances up to 60 km and focal depths down to 25 km. Digital waveform seismograms were obtained from local earthquakes in the NMSZ recorded by the Center for Earthquake Research and Information (CERI) at the University of Memphis. Using the coda normalization method, we tried to determine Q values and geometrical spreading exponents at 13 center frequencies. The scatter of the data and trade-off between the geometrical spreading and the quality factor did not allow us to simultaneously derive both these parameters from inversion. Assuming 1/ R 1.0 as the geometrical spreading function in the NMSZ, the Q P and Q S estimates increase with increasing frequency from 354 and 426 at 4 Hz to 729 and 1091 at 24 Hz, respectively. Fitting a power law equation to the Q estimates, we found the attenuation models for the P waves and S waves in the frequency range of 4 to 24 Hz as Q P = (115.80 ± 1.36) f (0.495 ± 0.129) and Q S = (161.34 ± 1.73) f (0.613 ± 0.067), respectively. We did not consider Q estimates from the coda normalization method for frequencies less than 4 Hz in the regression analysis since the decay of coda amplitude was not observed at most bandpass filtered seismograms for these frequencies. Q S/ Q P > 1, for 4 ≤ f ≤ 24 Hz as well as strong intrinsic attenuation, suggest that the crust beneath the NMSZ is partially fluid-saturated. Further, high scattering attenuation indicates the presence of a high level of small-scale heterogeneities inside the crust in this region.
Global gene expression in channel catfish after vaccination with an attenuated Edwardsiella ictaluri
USDA-ARS?s Scientific Manuscript database
To understand the global gene expression in channel catfish after immersion vaccination with an attenuated Edwardsiella ictaluri (AquaVac ESCTM), microarray analysis of 65,182 UniGene transcripts were performed. With a filter of false-discovery rate less than 0.05 and fold change greater than 2, a t...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhao, X.D.; Tsui, B.M.W.; Gregoriou, G.K.
The goal of the investigation was to study the effectiveness of the corrective reconstruction methods in cardiac SPECT using a realistic phantom and to qualitatively and quantitatively evaluate the reconstructed images using bull's-eye plots. A 3D mathematical phantom which realistically models the anatomical structures of the cardiac-torso region of patients was used. The phantom allows simulation of both the attenuation distribution and the uptake of radiopharmaceuticals in different organs. Also, the phantom can be easily modified to simulate different genders and variations in patient anatomy. Two-dimensional projection data were generated from the phantom and included the effects of attenuation andmore » detector response blurring. The reconstruction methods used in the study included the conventional filtered backprojection (FBP) with no attenuation compensation, and the first-order Chang algorithm, an iterative filtered backprojection algorithm (IFBP), the weighted least square conjugate gradient algorithm and the ML-EM algorithm with non-uniform attenuation compensation. The transaxial reconstructed images were rearranged into short-axis slices from which bull's-eye plots of the count density distribution in the myocardium were generated.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tang, S; Wang, W; Tang, X
2014-06-15
Purpose: With the major benefit in dealing with data truncation for ROI reconstruction, the algorithm of differentiated backprojection followed by Hilbert filtering (DBPF) is originally derived for image reconstruction from parallel- or fan-beam data. To extend its application for axial CB scan, we proposed the integration of the DBPF algorithm with 3-D weighting. In this work, we further propose the incorporation of Butterfly filtering into the 3-D weighted axial CB-DBPF algorithm and conduct an evaluation to verify its performance. Methods: Given an axial scan, tomographic images are reconstructed by the DBPF algorithm with 3-D weighting, in which streak artifacts existmore » along the direction of Hilbert filtering. Recognizing this orientation-specific behavior, a pair of orthogonal Butterfly filtering is applied on the reconstructed images with the horizontal and vertical Hilbert filtering correspondingly. In addition, the Butterfly filtering can also be utilized for streak artifact suppression in the scenarios wherein only partial scan data with an angular range as small as 270° are available. Results: Preliminary data show that, with the correspondingly applied Butterfly filtering, the streak artifacts existing in the images reconstructed by the 3-D weighted DBPF algorithm can be suppressed to an unnoticeable level. Moreover, the Butterfly filtering also works at the scenarios of partial scan, though the 3-D weighting scheme may have to be dropped because of no sufficient projection data are available. Conclusion: As an algorithmic step, the incorporation of Butterfly filtering enables the DBPF algorithm for CB image reconstruction from data acquired along either a full or partial axial scan.« less
Control algorithms for dynamic attenuators.
Hsieh, Scott S; Pelc, Norbert J
2014-06-01
The authors describe algorithms to control dynamic attenuators in CT and compare their performance using simulated scans. Dynamic attenuators are prepatient beam shaping filters that modulate the distribution of x-ray fluence incident on the patient on a view-by-view basis. These attenuators can reduce dose while improving key image quality metrics such as peak or mean variance. In each view, the attenuator presents several degrees of freedom which may be individually adjusted. The total number of degrees of freedom across all views is very large, making many optimization techniques impractical. The authors develop a theory for optimally controlling these attenuators. Special attention is paid to a theoretically perfect attenuator which controls the fluence for each ray individually, but the authors also investigate and compare three other, practical attenuator designs which have been previously proposed: the piecewise-linear attenuator, the translating attenuator, and the double wedge attenuator. The authors pose and solve the optimization problems of minimizing the mean and peak variance subject to a fixed dose limit. For a perfect attenuator and mean variance minimization, this problem can be solved in simple, closed form. For other attenuator designs, the problem can be decomposed into separate problems for each view to greatly reduce the computational complexity. Peak variance minimization can be approximately solved using iterated, weighted mean variance (WMV) minimization. Also, the authors develop heuristics for the perfect and piecewise-linear attenuators which do not require a priori knowledge of the patient anatomy. The authors compare these control algorithms on different types of dynamic attenuators using simulated raw data from forward projected DICOM files of a thorax and an abdomen. The translating and double wedge attenuators reduce dose by an average of 30% relative to current techniques (bowtie filter with tube current modulation) without increasing peak variance. The 15-element piecewise-linear dynamic attenuator reduces dose by an average of 42%, and the perfect attenuator reduces dose by an average of 50%. Improvements in peak variance are several times larger than improvements in mean variance. Heuristic control eliminates the need for a prescan. For the piecewise-linear attenuator, the cost of heuristic control is an increase in dose of 9%. The proposed iterated WMV minimization produces results that are within a few percent of the true solution. Dynamic attenuators show potential for significant dose reduction. A wide class of dynamic attenuators can be accurately controlled using the described methods.
NASA Astrophysics Data System (ADS)
Falocchi, Marco; Giovannini, Lorenzo; Franceschi, Massimiliano de; Zardi, Dino
2018-05-01
We present a refinement of the recursive digital filter proposed by McMillen (Boundary-Layer Meteorol 43:231-245, 1988), for separating surface-layer turbulence from low-frequency fluctuations affecting the mean flow, especially over complex terrain. In fact, a straightforward application of the filter causes both an amplitude attenuation and a forward phase shift in the filtered signal. As a consequence turbulence fluctuations, evaluated as the difference between the original series and the filtered one, as well as higher-order moments calculated from them, may be affected by serious inaccuracies. The new algorithm (i) produces a rigorous zero-phase filter, (ii) restores the amplitude of the low-frequency signal, and (iii) corrects all filter-induced signal distortions.
Li, Xinhua; Shi, Jim Q.; Zhang, Da; Singh, Sarabjeet; Padole, Atul; Otrakji, Alexi; Kalra, Mannudeep K.; Xu, X. George; Liu, Bob
2015-01-01
Purpose: To present a noninvasive technique for directly measuring the CT bow-tie filter attenuation with a linear array x-ray detector. Methods: A scintillator based x-ray detector of 384 pixels, 307 mm active length, and fast data acquisition (model X-Scan 0.8c4-307, Detection Technology, FI-91100 Ii, Finland) was used to simultaneously detect radiation levels across a scan field-of-view. The sampling time was as short as 0.24 ms. To measure the body bow-tie attenuation on a GE Lightspeed Pro 16 CT scanner, the x-ray tube was parked at the 12 o’clock position, and the detector was centered in the scan field at the isocenter height. Two radiation exposures were made with and without the bow-tie in the beam path. Each readout signal was corrected for the detector background offset and signal-level related nonlinear gain, and the ratio of the two exposures gave the bow-tie attenuation. The results were used in the geant4 based simulations of the point doses measured using six thimble chambers placed in a human cadaver with abdomen/pelvis CT scans at 100 or 120 kV, helical pitch at 1.375, constant or variable tube current, and distinct x-ray tube starting angles. Results: Absolute attenuation was measured with the body bow-tie scanned at 80–140 kV. For 24 doses measured in six organs of the cadaver, the median or maximum difference between the simulation results and the measurements on the CT scanner was 8.9% or 25.9%, respectively. Conclusions: The described method allows fast and accurate bow-tie filter characterization. PMID:26520720
Attenuation correction strategies for multi-energy photon emitters using SPECT
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pretorius, P.H.; King, M.A.; Pan, T.S.
1996-12-31
The aim of this study was to investigate whether the photopeak window projections from different energy photons can be combined into a single window for reconstruction or if it is better to not combine the projections due to differences in the attenuation maps required for each photon energy. The mathematical cardiac torso (MCAT) phantom was modified to simulate the uptake of Ga-67 in the human body. Four spherical hot tumors were placed in locations which challenged attenuation correction. An analytical 3D projector with attenuation and detector response included was used to generate projection sets. Data were reconstructed using filtered backprojectionmore » (FBP) reconstruction with Butterworth filtering in conjunction with one iteration of Chang attenuation correction, and with 5 and 10 iterations of ordered-subset maximum-likelihood expectation-maximization reconstruction. To serve as a standard for comparison, the projection sets obtained from the two energies were first reconstructed separately using their own attenuation maps. The emission data obtained from both energies were added and reconstructed using the following attenuation strategies: (1) the 93 keV attenuation map for attenuation correction, (2) the 185 keV attenuation map for attenuation correction, (3) using a weighted mean obtained from combining the 93 keV and 185 keV maps, and (4) an ordered subset approach which combines both energies. The central count ratio (CCR) and total count ratio (TCR) were used to compare the performance of the different strategies. Compared to the standard method, results indicate an over-estimation with strategy 1, an under-estimation with strategy 2 and comparable results with strategies 3 and 4. In all strategies, the CCR`s of sphere 4 were under-estimated, although TCR`s were comparable to that of the other locations. The weighted mean and ordered subset strategies for attenuation correction were of comparable accuracy to reconstruction of the windows separately.« less
Study of LCL filter performance for inverter fed grid connected system
NASA Astrophysics Data System (ADS)
Thamizh Thentral, T. M.; Geetha, A.; Subramani, C.
2018-04-01
The abandoned use of power electronic converters in the application of grid connected system paves a way for critical injected harmonics. Hence the use of filter becomes a significant play among the present scenario. Higher order passive filter is mostly preferred in this application because of its reduced cost and size. This paper focuses on the design of LCL filter for the reduction of injected harmonics. The reason behind choosing LCL filter is inductor sizing and good ripple component attenuation over the other conventional filters. This work is simulated in MATLAB platform and the results are prominent to the objectives mentioned above. Also, the simulation results are verified with the implemented hardware model.
Power line interference attenuation in multi-channel sEMG signals: Algorithms and analysis.
Soedirdjo, S D H; Ullah, K; Merletti, R
2015-08-01
Electromyogram (EMG) recordings are often corrupted by power line interference (PLI) even though the skin is prepared and well-designed instruments are used. This study focuses on the analysis of some of the recent and classical existing digital signal processing approaches have been used to attenuate, if not eliminate, the power line interference from EMG signals. A comparison of the signal to interference ratio (SIR) of the output signals is presented, for four methods: classical notch filter, spectral interpolation, adaptive noise canceller with phase locked loop (ANC-PLL) and adaptive filter, applied to simulated multichannel monopolar EMG signals with different SIR. The effect of each method on the shape of the EMG signals is also analyzed. The results show that ANC-PLL method gives the best output SIR and lowest shape distortion compared to the other methods. Classical notch filtering is the simplest method but some information might be lost as it removes both the interference and the EMG signals. Thus, it is obvious that notch filter has the lowest performance and it introduces distortion into the resulting signals.
Siipola, Sari M; Kotilainen, Titta; Sipari, Nina; Morales, Luis O; Lindfors, Anders V; Robson, T Matthew; Aphalo, Pedro J
2015-05-01
Plants synthesize phenolic compounds in response to certain environmental signals or stresses. One large group of phenolics, flavonoids, is considered particularly responsive to ultraviolet (UV) radiation. However, here we demonstrate that solar blue light stimulates flavonoid biosynthesis in the absence of UV-A and UV-B radiation. We grew pea plants (Pisum sativum cv. Meteor) outdoors, in Finland during the summer, under five types of filters differing in their spectral transmittance. These filters were used to (1) attenuate UV-B; (2) attenuate UV-B and UV-A < 370 nm; (3) attenuate UV-B and UV-A; (4) attenuate UV-B, UV-A and blue light; and (5) as a control not attenuating these wavebands. Attenuation of blue light significantly reduced the flavonoid content in leaf adaxial epidermis and reduced the whole-leaf concentrations of quercetin derivatives relative to kaempferol derivatives. In contrast, UV-B responses were not significant. These results show that pea plants regulate epidermal UV-A absorbance and accumulation of individual flavonoids by perceiving complex radiation signals that extend into the visible region of the solar spectrum. Furthermore, solar blue light instead of solar UV-B radiation can be the main regulator of phenolic compound accumulation in plants that germinate and develop outdoors. © 2014 John Wiley & Sons Ltd.
Losartan Attenuates Scar Formation in Filtering Bleb After Trabeculectomy.
Shi, Huimin; Wang, Huiying; Fu, Shuhao; Xu, Kang; Zhang, Xiaoyan; Xiao, Yiqin; Ye, Wen
2017-03-01
To examine the effects of losartan on scar formation after trabeculectomy and on fibrotic changes of human Tenon's fibroblasts (HTFs). Trabeculectomy was performed on New Zealand rabbits. They were randomized to receive one of the following treatments: 0.9% normal saline, mitomycin-C, or one of the three doses of losartan. Bleb morphology, IOP, and histopathology examination were performed. Primary cultured HTFs were treated with losartan or vehicle, with or without angiotensin II (Ang II). Cell proliferation was assessed by Cell Counting Kit-8 assay, and cell migration was detected by scratch wound and transwell assay. Transdifferentiation was evaluated through the expression of α-smooth muscle actin (α-SMA) by immunofluorescence, real-time PCR, and Western blot. The expression of fibronectin (FN) was evaluated by real-time PCR and Western blot. An amount of 5 mg/mL of losartan subconjunctival injection significantly decreased IOP postoperatively and attenuated wound healing of the filtering bleb in the rabbit model. Immunostaining results showed less myofibroblast and collagen deposition around the bleb area in the losartan-treated eyes. Losartan (10-5 M) in vitro significantly attenuated Ang II's stimulatory effects on proliferation and migration of HTFs. Expressions of α-SMA and FN in these cells were also decreased by losartan pretreatment. Losartan attenuates scar formation of filtering bleb after trabeculectomy likely via decreasing proliferation, migration, transdifferentiation, and extracellular matrix deposition of Tenon's fibroblasts. These results indicate that losartan may be an effective therapeutic agent in preventing bleb scar formation and in improving surgical outcome after trabeculectomy.
Dinico, Richard Steven
2003-01-01
Previous investigations have shown that natural attenuation and biodegradation of chlorinated volatile organic compounds (CVOCs) are substantial in shallow ground water beneath the 9-acre former landfill at Operable Unit 1 (OU 1), Naval Undersea Warfare Center (NUWC), Division Keyport, Washington. The U.S. Geological Survey (USGS) has continued to monitor ground-water geochemistry to assure that conditions remain favorable for contaminant biodegradation. This report presents the ground-water geochemical and selected CVOC data collected at OU 1 by the USGS during June 11-14, 2001 in support of the long-term monitoring for natural attenuation. Overall, the June 2001 data indicate that redox conditions in the upper aquifer remain favorable for reductive dechlorination of CVOCs because strongly reducing conditions persisted beneath much of the former landfill. Redox conditions in the intermediate aquifer down gradient of the landfill appear to have become more favorable for reductive dechlorination because June 2001 dissolved hydrogen concentrations indicated strongly reducing conditions there for the first time. Although changes in redox conditions were observed at certain wells during 2001, a longer monitoring period is needed to ascertain if phytoremediation activities are affecting the ground-water chemistry. A minor change to future monitoring is proposed. Filtered organic carbon (previously referred to as dissolved, and defined as that which passes through a 0.45-micrometer membrane filter) should be analyzed in the future rather than unfiltered (previously referred to as total) organic carbon because the filtered analysis may be a better measure of bioavailable organic carbon. Unfiltered and filtered organic carbon data were collected during June 2001 for comparison. Filtered organic carbon data collected in the future could be reasonably compared with historical unfiltered organic carbon data by multiplying the historical data by a factor of about 0.9.
Rapid and Simultaneous Prediction of Eight Diesel Quality Parameters through ATR-FTIR Analysis.
Nespeca, Maurilio Gustavo; Hatanaka, Rafael Rodrigues; Flumignan, Danilo Luiz; de Oliveira, José Eduardo
2018-01-01
Quality assessment of diesel fuel is highly necessary for society, but the costs and time spent are very high while using standard methods. Therefore, this study aimed to develop an analytical method capable of simultaneously determining eight diesel quality parameters (density; flash point; total sulfur content; distillation temperatures at 10% (T10), 50% (T50), and 85% (T85) recovery; cetane index; and biodiesel content) through attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy and the multivariate regression method, partial least square (PLS). For this purpose, the quality parameters of 409 samples were determined using standard methods, and their spectra were acquired in ranges of 4000-650 cm -1 . The use of the multivariate filters, generalized least squares weighting (GLSW) and orthogonal signal correction (OSC), was evaluated to improve the signal-to-noise ratio of the models. Likewise, four variable selection approaches were tested: manual exclusion, forward interval PLS (FiPLS), backward interval PLS (BiPLS), and genetic algorithm (GA). The multivariate filters and variables selection algorithms generated more fitted and accurate PLS models. According to the validation, the FTIR/PLS models presented accuracy comparable to the reference methods and, therefore, the proposed method can be applied in the diesel routine monitoring to significantly reduce costs and analysis time.
Rapid and Simultaneous Prediction of Eight Diesel Quality Parameters through ATR-FTIR Analysis
Hatanaka, Rafael Rodrigues; Flumignan, Danilo Luiz; de Oliveira, José Eduardo
2018-01-01
Quality assessment of diesel fuel is highly necessary for society, but the costs and time spent are very high while using standard methods. Therefore, this study aimed to develop an analytical method capable of simultaneously determining eight diesel quality parameters (density; flash point; total sulfur content; distillation temperatures at 10% (T10), 50% (T50), and 85% (T85) recovery; cetane index; and biodiesel content) through attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy and the multivariate regression method, partial least square (PLS). For this purpose, the quality parameters of 409 samples were determined using standard methods, and their spectra were acquired in ranges of 4000–650 cm−1. The use of the multivariate filters, generalized least squares weighting (GLSW) and orthogonal signal correction (OSC), was evaluated to improve the signal-to-noise ratio of the models. Likewise, four variable selection approaches were tested: manual exclusion, forward interval PLS (FiPLS), backward interval PLS (BiPLS), and genetic algorithm (GA). The multivariate filters and variables selection algorithms generated more fitted and accurate PLS models. According to the validation, the FTIR/PLS models presented accuracy comparable to the reference methods and, therefore, the proposed method can be applied in the diesel routine monitoring to significantly reduce costs and analysis time. PMID:29629209
Allner, S; Koehler, T; Fehringer, A; Birnbacher, L; Willner, M; Pfeiffer, F; Noël, P B
2016-05-21
The purpose of this work is to develop an image-based de-noising algorithm that exploits complementary information and noise statistics from multi-modal images, as they emerge in x-ray tomography techniques, for instance grating-based phase-contrast CT and spectral CT. Among the noise reduction methods, image-based de-noising is one popular approach and the so-called bilateral filter is a well known algorithm for edge-preserving filtering. We developed a generalization of the bilateral filter for the case where the imaging system provides two or more perfectly aligned images. The proposed generalization is statistically motivated and takes the full second order noise statistics of these images into account. In particular, it includes a noise correlation between the images and spatial noise correlation within the same image. The novel generalized three-dimensional bilateral filter is applied to the attenuation and phase images created with filtered backprojection reconstructions from grating-based phase-contrast tomography. In comparison to established bilateral filters, we obtain improved noise reduction and at the same time a better preservation of edges in the images on the examples of a simulated soft-tissue phantom, a human cerebellum and a human artery sample. The applied full noise covariance is determined via cross-correlation of the image noise. The filter results yield an improved feature recovery based on enhanced noise suppression and edge preservation as shown here on the example of attenuation and phase images captured with grating-based phase-contrast computed tomography. This is supported by quantitative image analysis. Without being bound to phase-contrast imaging, this generalized filter is applicable to any kind of noise-afflicted image data with or without noise correlation. Therefore, it can be utilized in various imaging applications and fields.
Kawai, Tatsuya; Takeuchi, Mitsuru; Hara, Masaki; Ohashi, Kazuya; Suzuki, Hirochika; Yamada, Kiyotaka; Sugimura, Yuya; Shibamoto, Yuta
2013-10-01
The effects of a tin filter on virtual non-enhanced (VNE) images created by dual-energy CT have not been well evaluated. To compare the accuracy of VNE images between those with and without a tin filter. Two different types of columnar phantoms made of agarose gel were evaluated. Phantom A contained various concentrations of iodine (4.5-1590 HU at 120 kVp). Phantom B consisted of a central component (0, 10, 25, and 40 mgI/cm(3)) and a surrounding component (0, 50, 100, and 200 mgI/cm(3)) with variable iodine concentration. They were scanned by dual-source CT in conventional single-energy mode and dual-energy mode with and without a tin filter. CT values on each gel at the corresponding points were measured and the accuracy of iodine removal was evaluated. On VNE images, the CT number of the gel of Phantom A fell within the range between -15 and +15 HU under 626 and 881 HU at single-energy 120 kVp with and without a tin filter, respectively. With attenuation over these thresholds, iodine concentration of gels was underestimated with the tin filter but overestimated without it. For Phantom B, the mean CT numbers on VNE images in the central gel component surrounded by the gel with iodine concentrations of 0, 50, 100, and 200 mgI/cm(3) were in the range of -19-+6 HU and 21-100 HU with and without the tin filter, respectively. Both with and without a tin filter, iodine removal was accurate under a threshold of iodine concentration. Although a surrounding structure with higher attenuation decreased the accuracy, a tin filter improved the margin of error.
A masking level difference due to harmonicity.
Treurniet, W C; Boucher, D R
2001-01-01
The role of harmonicity in masking was studied by comparing the effect of harmonic and inharmonic maskers on the masked thresholds of noise probes using a three-alternative, forced-choice method. Harmonic maskers were created by selecting sets of partials from a harmonic series with an 88-Hz fundamental and 45 consecutive partials. Inharmonic maskers differed in that the partial frequencies were perturbed to nearby values that were not integer multiples of the fundamental frequency. Average simultaneous-masked thresholds were as much as 10 dB lower with the harmonic masker than with the inharmonic masker, and this difference was unaffected by masker level. It was reduced or eliminated when the harmonic partials were separated by more than 176 Hz, suggesting that the effect is related to the extent to which the harmonics are resolved by auditory filters. The threshold difference was not observed in a forward-masking experiment. Finally, an across-channel mechanism was implicated when the threshold difference was found between a harmonic masker flanked by harmonic bands and a harmonic masker flanked by inharmonic bands. A model developed to explain the observed difference recognizes that an auditory filter output envelope is modulated when the filter passes two or more sinusoids, and that the modulation rate depends on the differences among the input frequencies. For a harmonic masker, the frequency differences of adjacent partials are identical, and all auditory filters have the same dominant modulation rate. For an inharmonic masker, however, the frequency differences are not constant and the envelope modulation rate varies across filters. The model proposes that a lower variability facilitates detection of a probe-induced change in the variability, thus accounting for the masked threshold difference. The model was supported by significantly improved predictions of observed thresholds when the predictor variables included envelope modulation rate variance measured using simulated auditory filters.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Saha, K; Barbarits, J; Humenik, R
Purpose: Chang’s mathematical formulation is a common method of attenuation correction applied on reconstructed Jaszczak phantom images. Though Chang’s attenuation correction method has been used for 360° angle acquisition, its applicability for 180° angle acquisition remains a question with one vendor’s camera software producing artifacts. The objective of this work is to ensure that Chang’s attenuation correction technique can be applied for reconstructed Jaszczak phantom images acquired in both 360° and 180° mode. Methods: The Jaszczak phantom filled with 20 mCi of diluted Tc-99m was placed on the patient table of Siemens e.cam™ (n = 2) and Siemens Symbia™ (nmore » = 1) dual head gamma cameras centered both in lateral and axial directions. A total of 3 scans were done at 180° and 2 scans at 360° orbit acquisition modes. Thirty two million counts were acquired for both modes. Reconstruction of the projection data was performed using filtered back projection smoothed with pre reconstruction Butterworth filter (order: 6, cutoff: 0.55). Reconstructed transaxial slices were attenuation corrected by Chang’s attenuation correction technique as implemented in the camera software. Corrections were also done using a modified technique where photon path lengths for all possible attenuation paths through a pixel in the image space were added to estimate the corresponding attenuation factor. The inverse of the attenuation factor was utilized to correct the attenuated pixel counts. Results: Comparable uniformity and noise were observed for 360° acquired phantom images attenuation corrected by the vendor technique (28.3% and 7.9%) and the proposed technique (26.8% and 8.4%). The difference in uniformity for 180° acquisition between the proposed technique (22.6% and 6.8%) and the vendor technique (57.6% and 30.1%) was more substantial. Conclusion: Assessment of attenuation correction performance by phantom uniformity analysis illustrated improved uniformity with the proposed algorithm compared to the camera software.« less
A highly linear baseband Gm—C filter for WLAN application
NASA Astrophysics Data System (ADS)
Lijun, Yang; Zheng, Gong; Yin, Shi; Zhiming, Chen
2011-09-01
A low voltage, highly linear transconductan—C (Gm—C) low-pass filter for wireless local area network (WLAN) transceiver application is proposed. This transmitter (Tx) filter adopts a 9.8 MHz 3rd-order Chebyshev low pass prototype and achieves 35 dB stop-band attenuation at 30 MHz frequency. By utilizing pseudo-differential linear-region MOS transconductors, the filter IIP3 is measured to be as high as 9.5 dBm. Fabricated in a 0.35 μm standard CMOS technology, the proposed filter chip occupies a 0.41 × 0.17 mm2 die area and consumes 3.36 mA from a 3.3-V power supply.
Control algorithms for dynamic attenuators
Hsieh, Scott S.; Pelc, Norbert J.
2014-01-01
Purpose: The authors describe algorithms to control dynamic attenuators in CT and compare their performance using simulated scans. Dynamic attenuators are prepatient beam shaping filters that modulate the distribution of x-ray fluence incident on the patient on a view-by-view basis. These attenuators can reduce dose while improving key image quality metrics such as peak or mean variance. In each view, the attenuator presents several degrees of freedom which may be individually adjusted. The total number of degrees of freedom across all views is very large, making many optimization techniques impractical. The authors develop a theory for optimally controlling these attenuators. Special attention is paid to a theoretically perfect attenuator which controls the fluence for each ray individually, but the authors also investigate and compare three other, practical attenuator designs which have been previously proposed: the piecewise-linear attenuator, the translating attenuator, and the double wedge attenuator. Methods: The authors pose and solve the optimization problems of minimizing the mean and peak variance subject to a fixed dose limit. For a perfect attenuator and mean variance minimization, this problem can be solved in simple, closed form. For other attenuator designs, the problem can be decomposed into separate problems for each view to greatly reduce the computational complexity. Peak variance minimization can be approximately solved using iterated, weighted mean variance (WMV) minimization. Also, the authors develop heuristics for the perfect and piecewise-linear attenuators which do not require a priori knowledge of the patient anatomy. The authors compare these control algorithms on different types of dynamic attenuators using simulated raw data from forward projected DICOM files of a thorax and an abdomen. Results: The translating and double wedge attenuators reduce dose by an average of 30% relative to current techniques (bowtie filter with tube current modulation) without increasing peak variance. The 15-element piecewise-linear dynamic attenuator reduces dose by an average of 42%, and the perfect attenuator reduces dose by an average of 50%. Improvements in peak variance are several times larger than improvements in mean variance. Heuristic control eliminates the need for a prescan. For the piecewise-linear attenuator, the cost of heuristic control is an increase in dose of 9%. The proposed iterated WMV minimization produces results that are within a few percent of the true solution. Conclusions: Dynamic attenuators show potential for significant dose reduction. A wide class of dynamic attenuators can be accurately controlled using the described methods. PMID:24877818
Study of the use of a nonlinear, rate limited, filter on pilot control signals
NASA Technical Reports Server (NTRS)
Adams, J. J.
1977-01-01
The use of a filter on the pilot's control output could improve the performance of the pilot-aircraft system. What is needed is a filter with a sharp high frequency cut-off, no resonance peak, and a minimum of lag at low frequencies. The present investigation studies the usefulness of a nonlinear, rate limited, filter in performing the needed function. The nonlinear filter is compared with a linear, first order filter, and no filter. An analytical study using pilot models and a simulation study using experienced test pilots was performed. The results showed that the nonlinear filter does promote quick, steady maneuvering. It is shown that the nonlinear filter attenuates the high frequency remnant and adds less phase lag to the low frequency signal than does the linear filter. It is also shown that the rate limit in the nonlinear filter can be set to be too restrictive, causing an unstable pilot-aircraft system response.
Simulation for noise cancellation using LMS adaptive filter
NASA Astrophysics Data System (ADS)
Lee, Jia-Haw; Ooi, Lu-Ean; Ko, Ying-Hao; Teoh, Choe-Yung
2017-06-01
In this paper, the fundamental algorithm of noise cancellation, Least Mean Square (LMS) algorithm is studied and enhanced with adaptive filter. The simulation of the noise cancellation using LMS adaptive filter algorithm is developed. The noise corrupted speech signal and the engine noise signal are used as inputs for LMS adaptive filter algorithm. The filtered signal is compared to the original noise-free speech signal in order to highlight the level of attenuation of the noise signal. The result shows that the noise signal is successfully canceled by the developed adaptive filter. The difference of the noise-free speech signal and filtered signal are calculated and the outcome implies that the filtered signal is approaching the noise-free speech signal upon the adaptive filtering. The frequency range of the successfully canceled noise by the LMS adaptive filter algorithm is determined by performing Fast Fourier Transform (FFT) on the signals. The LMS adaptive filter algorithm shows significant noise cancellation at lower frequency range.
Seismic Linear Noise Attenuation with Use of Radial Transform
NASA Astrophysics Data System (ADS)
Szymańska-Małysa, Żaneta
2018-03-01
One of the goals of seismic data processing is to attenuate the recorded noise in order to enable correct interpretation of the image. Radial transform has been used as a very effective tool in the attenuation of various types of linear noise, both numerical and real (such as ground roll, direct waves, head waves, guided waves etc). The result of transformation from offset - time (X - T) domain into apparent velocity - time (R - T) domain is frequency separation between reflections and linear events. In this article synthetic and real seismic shot gathers were examined. One example was targeted at far offset area of dataset where reflections and noise had similar apparent velocities and frequency bands. Another example was a result of elastic modelling where linear artefacts were produced. Bandpass filtering and scaling operation executed in radial domain attenuated all discussed types of linear noise very effectively. After noise reduction all further processing steps reveal better results, especially velocity analysis, migration and stacking. In all presented cases signal-to-noise ratio was significantly increased and reflections covered previously by noise were revealed. Power spectra of filtered seismic records preserved real dynamics of reflections.
Signal-Preserving Erratic Noise Attenuation via Iterative Robust Sparsity-Promoting Filter
Zhao, Qiang; Du, Qizhen; Gong, Xufei; ...
2018-04-06
Sparse domain thresholding filters operating in a sparse domain are highly effective in removing Gaussian random noise under Gaussian distribution assumption. Erratic noise, which designates non-Gaussian noise that consists of large isolated events with known or unknown distribution, also needs to be explicitly taken into account. However, conventional sparse domain thresholding filters based on the least-squares (LS) criterion are severely sensitive to data with high-amplitude and non-Gaussian noise, i.e., the erratic noise, which makes the suppression of this type of noise extremely challenging. Here, in this paper, we present a robust sparsity-promoting denoising model, in which the LS criterion ismore » replaced by the Huber criterion to weaken the effects of erratic noise. The random and erratic noise is distinguished by using a data-adaptive parameter in the presented method, where random noise is described by mean square, while the erratic noise is downweighted through a damped weight. Different from conventional sparse domain thresholding filters, definition of the misfit between noisy data and recovered signal via the Huber criterion results in a nonlinear optimization problem. With the help of theoretical pseudoseismic data, an iterative robust sparsity-promoting filter is proposed to transform the nonlinear optimization problem into a linear LS problem through an iterative procedure. The main advantage of this transformation is that the nonlinear denoising filter can be solved by conventional LS solvers. Lastly, tests with several data sets demonstrate that the proposed denoising filter can successfully attenuate the erratic noise without damaging useful signal when compared with conventional denoising approaches based on the LS criterion.« less
Signal-Preserving Erratic Noise Attenuation via Iterative Robust Sparsity-Promoting Filter
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhao, Qiang; Du, Qizhen; Gong, Xufei
Sparse domain thresholding filters operating in a sparse domain are highly effective in removing Gaussian random noise under Gaussian distribution assumption. Erratic noise, which designates non-Gaussian noise that consists of large isolated events with known or unknown distribution, also needs to be explicitly taken into account. However, conventional sparse domain thresholding filters based on the least-squares (LS) criterion are severely sensitive to data with high-amplitude and non-Gaussian noise, i.e., the erratic noise, which makes the suppression of this type of noise extremely challenging. Here, in this paper, we present a robust sparsity-promoting denoising model, in which the LS criterion ismore » replaced by the Huber criterion to weaken the effects of erratic noise. The random and erratic noise is distinguished by using a data-adaptive parameter in the presented method, where random noise is described by mean square, while the erratic noise is downweighted through a damped weight. Different from conventional sparse domain thresholding filters, definition of the misfit between noisy data and recovered signal via the Huber criterion results in a nonlinear optimization problem. With the help of theoretical pseudoseismic data, an iterative robust sparsity-promoting filter is proposed to transform the nonlinear optimization problem into a linear LS problem through an iterative procedure. The main advantage of this transformation is that the nonlinear denoising filter can be solved by conventional LS solvers. Lastly, tests with several data sets demonstrate that the proposed denoising filter can successfully attenuate the erratic noise without damaging useful signal when compared with conventional denoising approaches based on the LS criterion.« less
NASA Astrophysics Data System (ADS)
Shanmugavadivu, P.; Eliahim Jeevaraj, P. S.
2014-06-01
The Adaptive Iterated Functions Systems (AIFS) Filter presented in this paper has an outstanding potential to attenuate the fixed-value impulse noise in images. This filter has two distinct phases namely noise detection and noise correction which uses Measure of Statistics and Iterated Function Systems (IFS) respectively. The performance of AIFS filter is assessed by three metrics namely, Peak Signal-to-Noise Ratio (PSNR), Mean Structural Similarity Index Matrix (MSSIM) and Human Visual Perception (HVP). The quantitative measures PSNR and MSSIM endorse the merit of this filter in terms of degree of noise suppression and details/edge preservation respectively, in comparison with the high performing filters reported in the recent literature. The qualitative measure HVP confirms the noise suppression ability of the devised filter. This computationally simple noise filter broadly finds application wherein the images are highly degraded by fixed-value impulse noise.
Information-efficient spectral imaging sensor
Sweatt, William C.; Gentry, Stephen M.; Boye, Clinton A.; Grotbeck, Carter L.; Stallard, Brian R.; Descour, Michael R.
2003-01-01
A programmable optical filter for use in multispectral and hyperspectral imaging. The filter splits the light collected by an optical telescope into two channels for each of the pixels in a row in a scanned image, one channel to handle the positive elements of a spectral basis filter and one for the negative elements of the spectral basis filter. Each channel for each pixel disperses its light into n spectral bins, with the light in each bin being attenuated in accordance with the value of the associated positive or negative element of the spectral basis vector. The spectral basis vector is constructed so that its positive elements emphasize the presence of a target and its negative elements emphasize the presence of the constituents of the background of the imaged scene. The attenuated light in the channels is re-imaged onto separate detectors for each pixel and then the signals from the detectors are combined to give an indication of the presence or not of the target in each pixel of the scanned scene. This system provides for a very efficient optical determination of the presence of the target, as opposed to the very data intensive data manipulations that are required in conventional hyperspectral imaging systems.
Optimal Sharpening of Compensated Comb Decimation Filters: Analysis and Design
Troncoso Romero, David Ernesto
2014-01-01
Comb filters are a class of low-complexity filters especially useful for multistage decimation processes. However, the magnitude response of comb filters presents a droop in the passband region and low stopband attenuation, which is undesirable in many applications. In this work, it is shown that, for stringent magnitude specifications, sharpening compensated comb filters requires a lower-degree sharpening polynomial compared to sharpening comb filters without compensation, resulting in a solution with lower computational complexity. Using a simple three-addition compensator and an optimization-based derivation of sharpening polynomials, we introduce an effective low-complexity filtering scheme. Design examples are presented in order to show the performance improvement in terms of passband distortion and selectivity compared to other methods based on the traditional Kaiser-Hamming sharpening and the Chebyshev sharpening techniques recently introduced in the literature. PMID:24578674
Optimal sharpening of compensated comb decimation filters: analysis and design.
Troncoso Romero, David Ernesto; Laddomada, Massimiliano; Jovanovic Dolecek, Gordana
2014-01-01
Comb filters are a class of low-complexity filters especially useful for multistage decimation processes. However, the magnitude response of comb filters presents a droop in the passband region and low stopband attenuation, which is undesirable in many applications. In this work, it is shown that, for stringent magnitude specifications, sharpening compensated comb filters requires a lower-degree sharpening polynomial compared to sharpening comb filters without compensation, resulting in a solution with lower computational complexity. Using a simple three-addition compensator and an optimization-based derivation of sharpening polynomials, we introduce an effective low-complexity filtering scheme. Design examples are presented in order to show the performance improvement in terms of passband distortion and selectivity compared to other methods based on the traditional Kaiser-Hamming sharpening and the Chebyshev sharpening techniques recently introduced in the literature.
Sankoda, Kenshi; Murata, Kotaro; Tanihata, Mai; Suzuki, Kengo; Nomiyama, Kei; Shinohara, Ryota
2015-02-01
This study aimed to investigate the behavior of organic ultraviolet (UV) filters released by recreational activities along the Japanese coastline. Seasonal variations of organic UV filters in seawater were investigated at four different recreational beaches (Mogushi, Wakamiya, Tsurugahama, and Otachimisaki beaches) in both summer (July through August) and winter (December). Moreover, short time scale diurnal changes were monitored at Otachimisaki beach in summer. Of the four sunscreen agents tested in this study, two agents-2-ethylhexyl-4-methoxycinnamate (EHMC) and 2-ethylhexyl salicylate (EHS)-were detected in all samples, whereas octyl-dimethyl-p-aminobenzonic acid and 3-(4-methylbenzylidene)-camphor were lower than detection limits. In particular, EHMC, one of the most popular organic UV filters, was dominant. The highest concentration of EHMC was observed at 1,080 ng L(-1), a level that exceeds those of previous studies. Both EHMC and EHS concentrations showed significant (p < 0.05) seasonal variations with advancing summer suggesting direct input from recreational activities. The subsequent examination showed short time scale diurnal changes of organic UV filters on the beach. The results showed that diurnal changes in EHMC concentrations were correlated to the number of bathers. EHMC concentrations increased during the afternoon and decreased during the night, although complete attenuation during the night did not occur. EHMC persists along the coast due to low mobility and may persist the next day. This is the first study to show the natural attenuation behavior of organic UV filters along recreational beaches.
Attenuation correction strategies for multi-energy photon emitters using SPECT
NASA Astrophysics Data System (ADS)
Pretorius, P. H.; King, M. A.; Pan, T.-S.; Hutton, B. F.
1997-06-01
The aim of this study was to investigate whether the photopeak window projections from different energy photons can be combined into a single window for reconstruction or if it is better to not combine the projections due to differences in the attenuation maps required for each photon energy. The mathematical cardiac torso (MCAT) phantom was modified to simulate the uptake of Ga-67 in the human body. Four spherical hot tumors were placed in locations which challenged attenuation correction. An analytical 3D projector with attenuation and detector response included was used to generate projection sets. Data were reconstructed using filtered backprojection (FBP) reconstruction with Butterworth filtering in conjunction with one iteration of Chang attenuation correction, and with 5 and 10 iterations of ordered-subset maximum-likelihood expectation maximization (ML-OS) reconstruction. To serve as a standard for comparison, the projection sets obtained from the two energies were first reconstructed separately using their own attenuation maps. The emission data obtained from both energies were added and reconstructed using the following attenuation strategies: 1) the 93 keV attenuation map for attenuation correction, 2) the 185 keV attenuation map for attenuation correction, 3) using a weighted mean obtained from combining the 93 keV and 185 keV maps, and 4) an ordered subset approach which combines both energies. The central count ratio (CCR) and total count ratio (TCR) were used to compare the performance of the different strategies. Compared to the standard method, results indicate an over-estimation with strategy 1, an under-estimation with strategy 2 and comparable results with strategies 3 and 4. In all strategies, the CCRs of sphere 4 (in proximity to the liver, spleen and backbone) were under-estimated, although TCRs were comparable to that of the other locations. The weighted mean and ordered subset strategies for attenuation correction were of comparable accuracy to reconstruction of the windows separately. They are recommended for multi-energy photon SPECT imaging quantitation when there is a need to combine the acquisitions of multiple windows.
Ettlinger, Andreas; Neuner, Hans; Burgess, Thomas
2018-01-01
The topic of indoor positioning and indoor navigation by using observations from smartphone sensors is very challenging as the determined trajectories can be subject to significant deviations compared to the route travelled in reality. Especially the calculation of the direction of movement is the critical part of pedestrian positioning approaches such as Pedestrian Dead Reckoning (“PDR”). Due to distinct systematic effects in filtered trajectories, it can be assumed that there are systematic deviations present in the observations from smartphone sensors. This article has two aims: one is to enable the estimation of partial redundancies for each observation as well as for observation groups. Partial redundancies are a measure for the reliability indicating how well systematic deviations can be detected in single observations used in PDR. The second aim is to analyze the behavior of partial redundancy by modifying the stochastic and functional model of the Kalman filter. The equations relating the observations to the orientation are condition equations, which do not exhibit the typical structure of the Gauss-Markov model (“GMM”), wherein the observations are linear and can be formulated as functions of the states. To calculate and analyze the partial redundancy of the observations from smartphone-sensors used in PDR, the system equation and the measurement equation of a Kalman filter as well as the redundancy matrix need to be derived in the Gauss-Helmert model (“GHM”). These derivations are introduced in this article and lead to a novel Kalman filter structure based on condition equations, enabling reliability assessment of each observation. PMID:29385076
Ettlinger, Andreas; Neuner, Hans; Burgess, Thomas
2018-01-31
The topic of indoor positioning and indoor navigation by using observations from smartphone sensors is very challenging as the determined trajectories can be subject to significant deviations compared to the route travelled in reality. Especially the calculation of the direction of movement is the critical part of pedestrian positioning approaches such as Pedestrian Dead Reckoning ("PDR"). Due to distinct systematic effects in filtered trajectories, it can be assumed that there are systematic deviations present in the observations from smartphone sensors. This article has two aims: one is to enable the estimation of partial redundancies for each observation as well as for observation groups. Partial redundancies are a measure for the reliability indicating how well systematic deviations can be detected in single observations used in PDR. The second aim is to analyze the behavior of partial redundancy by modifying the stochastic and functional model of the Kalman filter. The equations relating the observations to the orientation are condition equations, which do not exhibit the typical structure of the Gauss-Markov model ("GMM"), wherein the observations are linear and can be formulated as functions of the states. To calculate and analyze the partial redundancy of the observations from smartphone-sensors used in PDR, the system equation and the measurement equation of a Kalman filter as well as the redundancy matrix need to be derived in the Gauss-Helmert model ("GHM"). These derivations are introduced in this article and lead to a novel Kalman filter structure based on condition equations, enabling reliability assessment of each observation.
A Study of a Mulilayer BPF with Attenuation Poles by Using Folded Resonators with Open-Circuited End
NASA Astrophysics Data System (ADS)
Kasamai, Masashi; Usie, Masahiko; Wada, Kouji
We propose a multilayer bandpass filter(BPF) with attenuation poles using folded resonators with open-circuited end. Firstly, the basic characteristics of a folded resonator with open-circuited end under the change of the parameters is examined by an electromagnetic simulator. Secondly, 3-pole multilayer BPFs using the resonators above are proposed, simulated and experimented. As a result, the bandpass characteristics with attenuation poles near the lower and higher side of the center frequency is realized by the proposed structure.
Mammographic x-ray unit kilovoltage test tool based on k-edge absorption effect.
Napolitano, Mary E; Trueblood, Jon H; Hertel, Nolan E; David, George
2002-09-01
A simple tool to determine the peak kilovoltage (kVp) of a mammographic x-ray unit has been designed. Tool design is based on comparing the effect of k-edge discontinuity of the attenuation coefficient for a series of element filters. Compatibility with the mammography accreditation phantom (MAP) to obtain a single quality control film is a second design objective. When the attenuation of a series of sequential elements is studied simultaneously, differences in the absorption characteristics due to the k-edge discontinuities are more evident. Specifically, when the incident photon energy is higher than the k-edge energy of a number of the elements and lower than the remainder, an inflection may be seen in the resulting attenuation data. The maximum energy of the incident photon spectra may be determined based on this inflection point for a series of element filters. Monte Carlo photon transport analysis was used to estimate the photon transmission probabilities for each of the sequential k-edge filter elements. The photon transmission corresponds directly to optical density recorded on mammographic x-ray film. To observe the inflection, the element filters chosen must have k-edge energies that span a range greater than the expected range of the end point energies to be determined. For the design, incident x-ray spectra ranging from 25 to 40 kVp were assumed to be from a molybdenum target. Over this range, the k-edge energy changes by approximately 1.5 keV between sequential elements. For this design 21 elements spanning an energy range from 20 to 50 keV were chosen. Optimum filter element thicknesses were calculated to maximize attenuation differences at the k-edge while maintaining optical densities between 0.10 and 3.00. Calculated relative transmission data show that the kVp could be determined to within +/-1 kV. To obtain experimental data, a phantom was constructed containing 21 different elements placed in an acrylic holder. MAP images were used to determine appropriate exposure techniques for a series of end point energies from 25 to 35 kVp. The average difference between the kVp determination and the calibrated dial setting was 0.8 and 1.0 kV for a Senographe 600 T and a Senographe DMR, respectively. Since the k-edge absorption energies of the filter materials are well known, independent calibration or a series of calibration curves is not required.
Robust incremental compensation of the light attenuation with depth in 3D fluorescence microscopy.
Kervrann, C; Legland, D; Pardini, L
2004-06-01
Summary Fluorescent signal intensities from confocal laser scanning microscopes (CLSM) suffer from several distortions inherent to the method. Namely, layers which lie deeper within the specimen are relatively dark due to absorption and scattering of both excitation and fluorescent light, photobleaching and/or other factors. Because of these effects, a quantitative analysis of images is not always possible without correction. Under certain assumptions, the decay of intensities can be estimated and used for a partial depth intensity correction. In this paper we propose an original robust incremental method for compensating the attenuation of intensity signals. Most previous correction methods are more or less empirical and based on fitting a decreasing parametric function to the section mean intensity curve computed by summing all pixel values in each section. The fitted curve is then used for the calculation of correction factors for each section and a new compensated sections series is computed. However, these methods do not perfectly correct the images. Hence, the algorithm we propose for the automatic correction of intensities relies on robust estimation, which automatically ignores pixels where measurements deviate from the decay model. It is based on techniques adopted from the computer vision literature for image motion estimation. The resulting algorithm is used to correct volumes acquired in CLSM. An implementation of such a restoration filter is discussed and examples of successful restorations are given.
Interference Alignment With Partial CSI Feedback in MIMO Cellular Networks
NASA Astrophysics Data System (ADS)
Rao, Xiongbin; Lau, Vincent K. N.
2014-04-01
Interference alignment (IA) is a linear precoding strategy that can achieve optimal capacity scaling at high SNR in interference networks. However, most existing IA designs require full channel state information (CSI) at the transmitters, which would lead to significant CSI signaling overhead. There are two techniques, namely CSI quantization and CSI feedback filtering, to reduce the CSI feedback overhead. In this paper, we consider IA processing with CSI feedback filtering in MIMO cellular networks. We introduce a novel metric, namely the feedback dimension, to quantify the first order CSI feedback cost associated with the CSI feedback filtering. The CSI feedback filtering poses several important challenges in IA processing. First, there is a hidden partial CSI knowledge constraint in IA precoder design which cannot be handled using conventional IA design methodology. Furthermore, existing results on the feasibility conditions of IA cannot be applied due to the partial CSI knowledge. Finally, it is very challenging to find out how much CSI feedback is actually needed to support IA processing. We shall address the above challenges and propose a new IA feasibility condition under partial CSIT knowledge in MIMO cellular networks. Based on this, we consider the CSI feedback profile design subject to the degrees of freedom requirements, and we derive closed-form trade-off results between the CSI feedback cost and IA performance in MIMO cellular networks.
Attenuation of spurious responses in electromechanical filters
Olsson, Roy H.; Hietala, Vincent M.
2018-04-10
A spur cancelling, electromechanical filter includes a first resonator having a first resonant frequency and one or more first spurious responses, and it also includes, electrically connected to the first resonator, a second resonator having a second resonant frequency and one or more second spurious responses. The first and second resonant frequencies are approximately identical, but the first resonator is physically non-identical to the second resonator. The difference between the resonators makes the respective spurious responses different. This allows for filters constructed from a cascade of these resonators to exhibit reduced spurious responses.
All optical controlled photonic integrated circuits using azo dye functionized sol-gel material
NASA Astrophysics Data System (ADS)
Ke, Xianjun
The main focus of this dissertation is development and characterization of all-optical controllable azo dye functionized sol gel material, demonstrating a PIC fabrication technique on glass substrate using such material, and exploration and feasibility demonstration of three PIC functional devices namely optical variable attenuator, optical switches, and optical tunable filters using the material. The realization of all the devices in this dissertation are based on one material: dye functionalized sol-gel material. A photochromic sol-gel material functionalized with azo dye was synthesized and characterized. It possesses a photochromic characteristic under the control of green laser beam illumination. The material characteristics suggest the possibility of a new promising material platform candidate for the fabrication of alloptical controlled photonic integrated circuits. As the first potential application of the dye functionalized sol-gel material, an alloptical variable attenuator was designed and demonstrated. The optical variable attenuation is achieved in Mach-Zehnder interferometric configuration through all-optical modulation of sol-gel waveguide phase shifters. A 2 x 2 optical switch based on multimode interference (MMI) waveguide structure is proposed in the dissertation. The schematic configuration of the optical switch consists of a cascade of two identical MMIs with two all-optical controlled phase shifters realized by using the photochromic sol-gel material. The cross or bar switch state of the optical switch is determined by the phase difference between the two sol-gel waveguide phase shifters. An all-optical tunable filter is designed and its feasibility demonstrated by using the sol-gel photochromic material. Except for the phase change demonstrated on sol-gel waveguide phase shifters, dynamic gratings were observed on sol-gel film when exposed to two interference beams. This reveals the possibility of realizing Bragg grating-based tunable filters. The schematic configuration of proposed tunable filters consists of a single straight waveguide embedded with a sol-gel waveguide. The wavelength tuning of the tunable filters is accomplished by varying the grating period.
Preliminary ground motion prediction equations for the Central and Eastern United States
NASA Astrophysics Data System (ADS)
Graizer, V.
2014-12-01
At the current stage I used the database created under the Next Generation Attenuations (NGA-East) project by Cramer et al. (2013). In contrast to the active tectonic environment in the Western US (WUS) the strong motion record database for the stable continental environment in the Central and Eastern US (CEUS) is not sufficient to create purely empirical ground motion prediction equations (GMPE) covering required for the PSHA magnitude (4.5
Stabilizing low-frequency oscillation with two-stage filter in Hall thrusters
NASA Astrophysics Data System (ADS)
Wei, Liqiu; Han, Liang; Ding, Yongjie; Yu, Daren; Zhang, Chaohai
2017-07-01
The use of a filter is the most common method to suppress low-frequency discharge current oscillation in Hall thrusters. The only form of filter in actual use involves RLC networks, which serve the purpose of reducing the level of conducted electromagnetic interference returning to the power processing unit, which is the function of a filter. Recently, the role of the filter in the oscillation control was introduced. It has been noted that the filter regulates the voltage across itself according to the variation of discharge current so as to decrease its fluctuation in the discharge circuit, which is the function of a controller. Therefore, a kind of two-stage filter is proposed to fulfill these two purposes, filtering and controlling, and the detailed design methods are discussed and verified. A current oscillation attenuation ratio of 10 was achieved by different capacitance and inductance combinations of the filter stage, and the standard deviation of low-frequency oscillations decreased from 3 A-1 A by the control stage in our experiment.
Method and apparatus for selective filtering of ions
Page, Jason S [Kennewick, WA; Tang, Keqi [Richland, WA; Smith, Richard D [Richland, WA
2009-04-07
An adjustable, low mass-to-charge (m/z) filter is disclosed employing electrospray ionization to block ions associated with unwanted low m/z species from entering the mass spectrometer and contributing their space charge to down-stream ion accumulation steps. The low-mass filter is made by using an adjustable potential energy barrier from the conductance limiting terminal electrode of an electrodynamic ion funnel, which prohibits species with higher ion mobilities from being transmitted. The filter provides a linear voltage adjustment of low-mass filtering from m/z values from about 50 to about 500. Mass filtering above m/z 500 can also be performed; however, higher m/z species are attenuated. The mass filter was evaluated with a liquid chromatography-mass spectrometry analysis of an albumin tryptic digest and resulted in the ability to block low-mass, "background" ions which account for 40-70% of the total ion current from the ESI source during peak elution.
NASA Astrophysics Data System (ADS)
Karaoǧlu, Haydar; Romanowicz, Barbara
2018-02-01
We present the results of synthetic tests that aim at evaluating the relative performance of three different definitions of misfit functionals in the context of 3-D imaging of shear wave attenuation in the earth's upper mantle at the global scale, using long-period full-waveform data. The synthetic tests are conducted with simple hypothetical upper-mantle models that contain Qμ anomalies centred at different depths and locations, with or without additional seismic velocity anomalies. To build synthetic waveform data sets, we performed simulations of 50 events in the hypothetical (target) models, using the spectral element method, filtered in the period range 60-400 s. The selected events are chosen among 273 events used in the development of radially anisotropic model SEMUCB-WM1 and recorded at 495 stations worldwide. The synthetic Z-component waveforms correspond to paths and time intervals (fundamental mode and overtone Rayleigh waves) that exist in the real waveform data set. The inversions for shear attenuation structure are carried out using a Gauss-Newton optimization scheme in which the gradient and Hessian are computed using normal mode perturbation theory. The three different misfit functionals considered are based on time domain waveform (WF) and waveform envelope (E-WF) differences, as well as spectral amplitude ratios (SA), between observed and predicted waveforms. We evaluate the performance of the three misfit functional definitions in the presence of seismic noise and unresolved S-wave velocity heterogeneity and discuss the relative importance of physical dispersion effects due to 3-D Qμ structure. We observed that the performance of WF is poorer than the other two misfit functionals in recovering attenuation structure, unless anelastic dispersion effects are taken into account in the calculation of partial derivatives. WF also turns out to be more sensitive to seismic noise than E-WF and SA. Overall, SA performs best for attenuation imaging. Our tests show that it is important to account for 3-D elastic effects (focusing) before inverting for Qμ. Additionally, we show that including high signal-to-noise ratio overtone wave packets is necessary to resolve Qμ structure at depths greater than 250 km.
SHARDS: A Global View of the Star Formation Activity at z ~ 0.84 and z ~ 1.23
NASA Astrophysics Data System (ADS)
Cava, Antonio; Pérez-González, Pablo G.; Eliche-Moral, M. Carmen; Ricciardelli, Elena; Vidal-García, Alba; Alcalde Pampliega, Belen; Alonso-Herrero, Almudena; Barro, Guillermo; Cardiel, Nicolas; Cenarro, A. Javier; Charlot, Stephane; Daddi, Emanuele; Dessauges-Zavadsky, Miroslava; Domínguez Sánchez, Helena; Espino-Briones, Nestor; Esquej, Pilar; Gallego, Jesus; Hernán-Caballero, Antonio; Huertas-Company, Marc; Koekemoer, Anton M.; Muñoz-Tunon, Casiana; Rodriguez-Espinosa, Jose M.; Rodríguez-Muñoz, Lucia; Tresse, Laurence; Villar, Victor
2015-10-01
In this paper, we present a comprehensive analysis of star-forming galaxies (SFGs) at intermediate redshifts (z ˜ 1). We combine the ultra-deep optical spectro-photometric data from the Survey for High-z Absorption Red and Dead Sources (SHARDS) with deep UV-to-FIR observations in the GOODS-N field. Exploiting two of the 25 SHARDS medium-band filters, F687W17 and F823W17, we select [O ii] emission line galaxies at z ˜ 0.84 and z ˜ 1.23 and characterize their physical properties. Their rest-frame equivalent widths (EWrf([O ii])), line fluxes, luminosities, star formation rates (SFRs), and dust attenuation properties are investigated. The evolution of EWrf([O ii]) closely follows the SFR density evolution of the universe, with a trend of EWrf([O ii]) \\propto (1 + z)3 up to redshift z ≃ 1, followed by a possible flattening. The SF properties of the galaxies selected on the basis of their [O ii] emission are compared with complementary samples of SFGs selected by their MIR and FIR emission, and also with a general mass-selected sample of galaxies at the same redshifts. We demonstrate observationally that the UVJ diagram (or, similarly, a cut in the specific SFR) is only partially able to distinguish the quiescent galaxies from the SFGs. The SFR-M* relation is investigated for the different samples, yielding a logarithmic slope ˜1, in good agreement with previous results. The dust attenuations derived from different SFR indicators (UV(1600), UV(2800), [O ii], IR) are compared and show clear trends with respect to both the stellar mass and total SFR, with more massive and highly star-forming galaxies being affected by stronger dust attenuation.
NASA Astrophysics Data System (ADS)
Fakhri, G. El; Kijewski, M. F.; Moore, S. C.
2001-06-01
Estimates of SPECT activity within certain deep brain structures could be useful for clinical tasks such as early prediction of Alzheimer's disease with Tc-99m or Parkinson's disease with I-123; however, such estimates are biased by poor spatial resolution and inaccurate scatter and attenuation corrections. We compared an analytical approach (AA) of more accurate quantitation to a slower iterative approach (IA). Monte Carlo simulated projections of 12 normal and 12 pathologic Tc-99m perfusion studies, as well as 12, normal and 12 pathologic I-123 neurotransmission studies, were generated using a digital brain phantom and corrected for scatter by a multispectral fitting procedure. The AA included attenuation correction by a modified Metz-Fan algorithm and activity estimation by a technique that incorporated Metz filtering to compensate for variable collimator response (VCR), IA-modeled attenuation, and VCR in the projector/backprojector of an ordered subsets-expectation maximization (OSEM) algorithm. Bias and standard deviation over the 12 normal and 12 pathologic patients were calculated with respect to the reference values in the corpus callosum, caudate nucleus, and putamen. The IA and AA yielded similar quantitation results in both Tc-99m and I-123 studies in all brain structures considered in both normal and pathologic patients. The bias with respect to the reference activity distributions was less than 7% for Tc-99m studies, but greater than 30% for I-123 studies, due to partial volume effect in the striata. Our results were validated using I-123 physical acquisitions of an anthropomorphic brain phantom. The IA yielded quantitation accuracy comparable to that obtained with IA, while requiring much less processing time. However, in most conditions, IA yielded lower noise for the same bias than did AA.
Plasma Parameters From Reentry Signal Attenuation
Statom, T. K.
2018-02-27
This study presents the application of a theoretically developed method that provides plasma parameter solution space information from measured RF attenuation that occurs during reentry. The purpose is to provide reentry plasma parameter information from the communication signal attenuation. The theoretical development centers around the attenuation and the complex index of refraction. The methodology uses an imaginary index of the refraction matching algorithm with a tolerance to find suitable solutions that satisfy the theory. The imaginary matching terms are then used to determine the real index of refraction resulting in the complex index of refraction. Then a filter is usedmore » to reject nonphysical solutions. Signal attenuation-based plasma parameter properties investigated include the complex index of refraction, plasma frequency, electron density, collision frequency, propagation constant, attenuation constant, phase constant, complex plasma conductivity, and electron mobility. RF plasma thickness attenuation is investigated and compared to the literature. Finally, similar plasma thickness for a specific signal attenuation can have different plasma properties.« less
Plasma Parameters From Reentry Signal Attenuation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Statom, T. K.
This study presents the application of a theoretically developed method that provides plasma parameter solution space information from measured RF attenuation that occurs during reentry. The purpose is to provide reentry plasma parameter information from the communication signal attenuation. The theoretical development centers around the attenuation and the complex index of refraction. The methodology uses an imaginary index of the refraction matching algorithm with a tolerance to find suitable solutions that satisfy the theory. The imaginary matching terms are then used to determine the real index of refraction resulting in the complex index of refraction. Then a filter is usedmore » to reject nonphysical solutions. Signal attenuation-based plasma parameter properties investigated include the complex index of refraction, plasma frequency, electron density, collision frequency, propagation constant, attenuation constant, phase constant, complex plasma conductivity, and electron mobility. RF plasma thickness attenuation is investigated and compared to the literature. Finally, similar plasma thickness for a specific signal attenuation can have different plasma properties.« less
Hadley, Odelle L; Corrigan, Craig E; Kirchstetter, Thomas W
2008-11-15
This study presents a method for analyzing the black carbon (BC) mass loading on a quartz fiber filter using a modified thermal-optical analysis method, wherein light transmitted through the sample is measured over a spectral region instead of at a single wavelength. Evolution of the spectral light transmission signal depends on the relative amounts of light-absorbing BC and char, the latter of which forms when organic carbon in the sample pyrolyzes during heating. Absorption selectivities of BC and char are found to be distinct and are used to apportion the amount of light attenuated by each component in the sample. Light attenuation is converted to mass concentration on the basis of derived mass attenuation efficiencies (MAEs) of BC and char. The fractions of attenuation due to each component are scaled by their individual MAE values and added together as the total mass of light absorbing carbon (LAC). An iterative algorithm is used to find the MAE values for both BC and char that provide the best fit to the carbon mass remaining on the filter (derived from direct measurements of thermally evolved CO2) at temperatures higher than 480 degrees C. This method was applied to measure the BC concentration in precipitation samples collected in northern California. The uncertainty in the measured BC concentration of samples that contained a high concentration of organics susceptible to char ranged from 12% to 100%, depending on the mass loading of BC on the filter. The lower detection limit for this method was approximately 0.35 microg of BC, and the uncertainty approached 20% for BC mass loading greater than 1.0 microg of BC.
NASA Astrophysics Data System (ADS)
Arevalo-Lopez, H. S.; Levin, S. A.
2016-12-01
The vertical component of seismic wave reflections is contaminated by surface noise such as ground roll and secondary scattering from near surface inhomogeneities. A common method for attenuating these, unfortunately often aliased, arrivals is via velocity filtering and/or multichannel stacking. 3D-3C acquisition technology provides two additional sources of information about the surface wave noise that we exploit here: (1) areal receiver coverage, and (2) a pair of horizontal components recorded at the same location as the vertical component. Areal coverage allows us to segregate arrivals at each individual receiver or group of receivers by direction. The horizontal components, having much less compressional reflection body wave energy than the vertical component, provide a template of where to focus our energies on attenuating the surface wave arrivals. (In the simplest setting, the vertical component is a scaled 90 degree phase rotated version of the radial horizontal arrival, a potential third possible lever we have not yet tried to integrate.) The key to our approach is to use the magnitude of the horizontal components to outline a data-adaptive "velocity" filter region in the w-Kx-Ky domain. The big advantage for us is that even in the presence of uneven receiver geometries, the filter automatically tracks through aliasing without manual sculpting and a priori velocity and dispersion estimation. The method was applied to an aliased synthetic dataset based on a five layer earth model which also included shallow scatterers to simulate near-surface inhomogeneities and successfully removed both the ground roll and scatterers from the vertical component (Figure 1).
The N/Rev phenomenon in simulating a blade-element rotor system
NASA Technical Reports Server (NTRS)
Mcfarland, R. E.
1983-01-01
When a simulation model produces frequencies that are beyond the bandwidth of a discrete implementation, anomalous frequencies appear within the bandwidth. Such is the case with blade element models of rotor systems, which are used in the real time, man in the loop simulation environment. Steady state, high frequency harmonics generated by these models, whether aliased or not, obscure piloted helicopter simulation responses. Since these harmonics are attenuated in actual rotorcraft (e.g., because of structural damping), a faithful environment representation for handling qualities purposes may be created from the original model by using certain filtering techniques, as outlined here. These include harmonic consideration, conventional filtering, and decontamination. The process of decontamination is of special interest because frequencies of importance to simulation operation are not attenuated, whereas superimposed aliased harmonics are.
Optical evaluation of the wave filtering properties of graded undulated lattices
NASA Astrophysics Data System (ADS)
Trainiti, G.; Rimoli, J. J.; Ruzzene, M.
2018-03-01
We investigate and experimentally demonstrate the elastic wave filtering properties of graded undulated lattices. Square reticulates composed of curved beams are characterized by graded mechanical properties which result from the spatial modulation of the curvature parameter. Among such properties, the progressive formation of frequency bandgaps leads to strong wave attenuation over a broad frequency range. The experimental investigation of wave transmission and the detection of full wavefields effectively illustrate this behavior. Transmission measurements are conducted using a scanning laser Doppler vibrometer, while a dedicated digital image correlation procedure is implemented to capture in-plane wave motion at selected frequencies. The presented results illustrate the broadband attenuation characteristics resulting from spatial grading of the lattice curvature, whose in-depth investigation is enabled by the presented experimental procedures.
Energy Conservation in Optical Fibers With Distributed Brick-Walls Filters
NASA Astrophysics Data System (ADS)
Garcia, Javier; Ghozlan, Hassan; Kramer, Gerhard
2018-05-01
A band-pass filtering scheme is proposed to mitigate spectral broadening and channel coupling in the Nonlinear Schr\\"odinger (NLS) fiber optic channel. The scheme is modeled by modifying the NLS Equation to include an attenuation profile with multiple brick-wall filters centered at different frequencies. It is shown that this brick-walls profile conserves the total in-band energy of the launch signal. Furthermore, energy fluctuations between the filtered channels are characterized, and conditions on the channel spacings are derived that ensure energy conservation in each channel. The maximum spectral efficiency of such a system is derived, and a constructive rule for achieving it using Sidon sequences is provided.
An ultra-low-power filtering technique for biomedical applications.
Zhang, Tan-Tan; Mak, Pui-In; Vai, Mang-I; Mak, Peng-Un; Wan, Feng; Martins, R P
2011-01-01
This paper describes an ultra-low-power filtering technique for biomedical applications designated as T-wave sensing in heart-activities detection systems. The topology is based on a source-follower-based Biquad operating in the sub-threshold region. With the intrinsic advantages of simplicity and high linearity of the source-follower, ultra-low-cutoff filtering can be achieved, simultaneously with ultra low power and good linearity. An 8(th)-order 2.4-Hz lowpass filter design example optimized in a 0.35-μm CMOS process was designed achieving over 85-dB dynamic range, 74-dB stopband attenuation and consuming only 0.36 nW at a 3-V supply.
Ploux, Sylvain; Swerdlow, Charles D; Eschalier, Romain; Monteil, Benjamin; Ouali, Sana; Haïssaguerre, Michel; Bordachar, Pierre
2016-07-01
Diaphragmatic myopotential oversensing (DMO) causes inhibition of pacing and inappropriate detection of ventricular fibrillation in implantable cardioverter defibrillators (ICDs). It occurs almost exclusively with integrated bipolar leads and is extremely rare with dedicated bipolar leads. If DMO cannot be corrected by reducing programmed sensitivity, ventricular lead revision is often required. The new Low Frequency Attenuation (LFA) filter in St. Jude Medical ICDs (St. Jude Medical, Sylmar, CA, USA) alters the sensing bandpass to reduce T-wave oversensing. This paper aims to present the LFA filter as a reversible cause of DMO. Unnecessary lead revision can be avoided by the simple programming solution of deactivating this LFA filter. ©2016 Wiley Periodicals, Inc.
Monolithic pattern-sensitive detector
Berger, Kurt W.
2000-01-01
Extreme ultraviolet light (EUV) is detected using a precisely defined reference pattern formed over a shallow junction photodiode. The reference pattern is formed in an EUV absorber preferably comprising nickel or other material having EUV- and other spectral region attenuating characteristics. An EUV-transmissive energy filter is disposed between a passivation oxide layer of the photodiode and the EUV transmissive energy filter. The device is monolithically formed to provide robustness and compactness.
Wear, Keith A
2010-10-01
The presence of two longitudinal waves in porous media is predicted by Biot's theory and has been confirmed experimentally in cancellous bone. When cancellous bone samples are interrogated in through-transmission, these two waves can overlap in time. Previously, the Modified Least-Squares Prony's (MLSP) method was validated for estimation of amplitudes, attenuation coefficients, and phase velocities of fast and slow waves, but tended to overestimate phase velocities by up to about 5%. In the present paper, a pre-processing chirp filter to mitigate the phase velocity bias is derived. The MLSP/chirp filter (MLSPCF) method was tested for decomposition of a 500 kHz-center-frequency signal containing two overlapping components: one passing through a low-density-polyethylene plate (fast wave) and another passing through a cancellous-bone-mimicking phantom material (slow wave). The chirp filter reduced phase velocity bias from 100 m/s (5.1%) to 69 m/s (3.5%) (fast wave) and from 29 m/s (1.9%) to 10 m/s (0.7%) (slow wave). Similar improvements were found for 1) measurements in polycarbonate (fast wave) and a cancellous-bone-mimicking phantom (slow wave), and 2) a simulation based on parameters mimicking bovine cancellous bone. The MLSPCF method did not offer consistent improvement in estimates of attenuation coefficient or amplitude.
NASA Astrophysics Data System (ADS)
Liu, Yahui; Fan, Xiaoqian; Lv, Chen; Wu, Jian; Li, Liang; Ding, Dawei
2018-02-01
Information fusion method of INS/GPS navigation system based on filtering technology is a research focus at present. In order to improve the precision of navigation information, a navigation technology based on Adaptive Kalman Filter with attenuation factor is proposed to restrain noise in this paper. The algorithm continuously updates the measurement noise variance and processes noise variance of the system by collecting the estimated and measured values, and this method can suppress white noise. Because a measured value closer to the current time would more accurately reflect the characteristics of the noise, an attenuation factor is introduced to increase the weight of the current value, in order to deal with the noise variance caused by environment disturbance. To validate the effectiveness of the proposed algorithm, a series of road tests are carried out in urban environment. The GPS and IMU data of the experiments were collected and processed by dSPACE and MATLAB/Simulink. Based on the test results, the accuracy of the proposed algorithm is 20% higher than that of a traditional Adaptive Kalman Filter. It also shows that the precision of the integrated navigation can be improved due to the reduction of the influence of environment noise.
ACTS Ka-band Propagation Research in a Spatially Diversified Network with Two USAT Ground Stations
NASA Technical Reports Server (NTRS)
Kalu, Alex; Acousta, R.; Durand, S.; Emrich, Carol; Ventre, G.; Wilson, W.
1999-01-01
Congestion in the radio spectrum below 18 GHz is stimulating greater interest in the Ka (20/30 GHz) frequency band. Transmission at these shorter wavelengths is greatly influenced by rain resulting in signal attenuation and decreased link availability. The size and projected cost of Ultra Small Aperture Terminals (USATS) make site diversity methodology attractive for rain fade compensation. Separation distances between terminals must be small to be of interest commercially. This study measures diversity gain at a separation distance <5 km and investigates utilization of S-band weather radar reflectivity in predicting diversity gain. Two USAT ground stations, separated by 2.43 km for spatial diversity, received a continuous Ka-band tone sent from NASA Glenn Research Center via the Advanced Communications Technology Satellite (ACTS) steerable antenna beam. Received signal power and rainfall were measured, and Weather Surveillance Radar-1998 Doppler (WSR-88D) data were obtained as a measure of precipitation along the USAT-to-ACTS slant path. Signal attenuation was compared for the two sites, and diversity gain was calculated for fades measured on eleven days. Correlation of WSR-88D S-band reflectivity with measured Ka-band attenuation consisted of locating radar volume elements along each slant path, converting reflectivity to Ka-band attenuation with rain rate calculation as an intermediate step. Specific attenuation for each associated path segment was summed, resulting in total attenuation along the slant path. Derived Ka-band attenuation did not correlate closely with empirical data (r = 0.239), but a measured signal fade could be matched with an increase in radar reflectivity in all fade events. Applying a low pass filter to radar reflectivity prior to deriving Ka-band attenuation improved the correlation between measured and derived signal attenuation (r = 0.733). Results indicate that site diversity at small separation distances is a viable means of rain fade compensation, and that existing models underestimate diversity gain for a subtropical climate such as Florida. Also, filtered WSR-88D reflectivity can be used for optimizing diversity terminal placement by comparing derived Ka- band attenuation between the diversity sites.
NASA Technical Reports Server (NTRS)
Witte, W. G.; Whitlock, C. H.; Usry, J. W.; Morris, W. D.; Gurganus, E. A.
1981-01-01
Reflectance, chromaticity, diffuse attenuation, beam attenuation, and several other physical and chemical properties were measured for various water mixtures of lake bottom sediment. Mixture concentrations range from 5 ppm to 700 ppm by weight of total suspended solids in filtered deionized tap water. Upwelled reflectance is a nonlinear function of remote sensing wave lengths. Near-infrared wavelengths are useful for monitoring highly turbid waters with sediment concentrations above 100 ppm. It is found that both visible and near infrared wavelengths, beam attenuation correlates well with total suspended solids ranging over two orders of magnitude.
Design of microstrip components by computer
NASA Technical Reports Server (NTRS)
Cisco, T. C.
1972-01-01
Development of computer programs for component analysis and design aids used in production of microstrip components is discussed. System includes designs for couplers, filters, circulators, transformers, power splitters, diode switches, and attenuators.
A periodic spatio-spectral filter for event-related potentials.
Ghaderi, Foad; Kim, Su Kyoung; Kirchner, Elsa Andrea
2016-12-01
With respect to single trial detection of event-related potentials (ERPs), spatial and spectral filters are two of the most commonly used pre-processing techniques for signal enhancement. Spatial filters reduce the dimensionality of the data while suppressing the noise contribution and spectral filters attenuate frequency components that most likely belong to noise subspace. However, the frequency spectrum of ERPs overlap with that of the ongoing electroencephalogram (EEG) and different types of artifacts. Therefore, proper selection of the spectral filter cutoffs is not a trivial task. In this research work, we developed a supervised method to estimate the spatial and finite impulse response (FIR) spectral filters, simultaneously. We evaluated the performance of the method on offline single trial classification of ERPs in datasets recorded during an oddball paradigm. The proposed spatio-spectral filter improved the overall single-trial classification performance by almost 9% on average compared with the case that no spatial filters were used. We also analyzed the effects of different spectral filter lengths and the number of retained channels after spatial filtering. Copyright © 2016. Published by Elsevier Ltd.
Kadota, Michio; Tanaka, Shuji
2015-05-01
A cognitive radio terminal using vacant frequency bands of digital TV (DTV) channels, i.e., TV white space, strongly requires a compact tunable filter covering a wide frequency range of the DTV band (470 to 710 MHz in Japan). In this study, a T-type ladder filter using ultra-wideband shear horizontal mode plate wave resonators was fabricated, and a low peak insertion loss of 0.8 dB and an ultra-large 6 dB bandwidth of 240 MHz (41%) were measured in the DTV band. In addition, bandpass filters with different center frequencies of 502 and 653 MHz at 6 dB attenuation were numerically synthesized based on the same T-type ladder filter in conjunction with band rejection filters with different frequencies. The results suggest that the combination of the wideband T-type ladder filter and the band rejection filters connected with variable capacitors enables a tunable filter with large tunability of frequency and bandwidth as well as large rejection at the adjacent channels of an available TV white space.
Online EEG artifact removal for BCI applications by adaptive spatial filtering.
Guarnieri, Roberto; Marino, Marco; Barban, Federico; Ganzetti, Marco; Mantini, Dante
2018-06-28
The performance of brain computer interfaces (BCIs) based on electroencephalography (EEG) data strongly depends on the effective attenuation of artifacts that are mixed in the recordings. To address this problem, we have developed a novel online EEG artifact removal method for BCI applications, which combines blind source separation (BSS) and regression (REG) analysis. The BSS-REG method relies on the availability of a calibration dataset of limited duration for the initialization of a spatial filter using BSS. Online artifact removal is implemented by dynamically adjusting the spatial filter in the actual experiment, based on a linear regression technique. Our results showed that the BSS-REG method is capable of attenuating different kinds of artifacts, including ocular and muscular, while preserving true neural activity. Thanks to its low computational requirements, BSS-REG can be applied to low-density as well as high-density EEG data. We argue that BSS-REG may enable the development of novel BCI applications requiring high-density recordings, such as source-based neurofeedback and closed-loop neuromodulation. © 2018 IOP Publishing Ltd.
An approach for fixed coefficient RNS-based FIR filter
NASA Astrophysics Data System (ADS)
Srinivasa Reddy, Kotha; Sahoo, Subhendu Kumar
2017-08-01
In this work, an efficient new modular multiplication method for {2k-1, 2k, 2k+1-1} moduli set is proposed to implement a residue number system (RNS)-based fixed coefficient finite impulse response filter. The new multiplication approach reduces the number of partial products by using pre-loaded product block. The reduction in partial products with the proposed modular multiplication improves the clock frequency and reduces the area and power as compared with the conventional modular multiplication. Further, the present approach eliminates a binary number to residue number converter circuit, which is usually needed at the front end of RNS-based system. In this work, two fixed coefficient filter architectures with the new modular multiplication approach are proposed. The filters are implemented using Verilog hardware description language. The United Microelectronics Corporation 90 nm technology library has been used for synthesis and the results area, power and delay are obtained with the help of Cadence register transfer level compiler. The power delay product (PDP) is also considered for performance comparison among the proposed filters. One of the proposed architecture is found to improve PDP gain by 60.83% as compared with the filter implemented with conventional modular multiplier. The filters functionality is validated with the help of Altera DSP Builder.
The effect of bandwidth on filter instrument total ozone accuracy
NASA Technical Reports Server (NTRS)
Basher, R. E.
1977-01-01
The effect of the width and shape of the New Zealand filter instrument's passbands on measured total-ozone accuracy is determined using a numerical model of the spectral measurement process. The model enables the calculation of corrections for the 'bandwidth-effect' error and shows that highly attenuating passband skirts and well-suppressed leakage bands are at least as important as narrow half-bandwidths. Over typical ranges of airmass and total ozone, the range in the bandwidth-effect correction is about 2% in total ozone for the filter instrument, compared with about 1% for the Dobson instrument.
Tunable high-channel-count bandstop graphene plasmonic filters based on plasmon induced transparency
NASA Astrophysics Data System (ADS)
Zhang, Zhengren; Long, Yang; Ma, Pengyu; Li, Hongqiang
2017-11-01
A high-channel-count bandstop graphene plasmonic filter based on ultracompact plasmonic structure is proposed in this paper. It consists of graphene waveguide side-coupled with a series of graphene filtering units. The study shows that the waveguide-resonator system performs a multiple plasmon induced transparency (PIT) phenomenon. By carefully adjusting the Fermi level of the filtering units, any two adjacent transmitted dips which belong to different PIT units can produce coherent coupling superposition enhancement. This property prevents the attenuation of the high-frequency transmission dips of multiple PIT and leads to an excellent bandstop filter with multiple channels. Specifically, the bandwidth and modulation depth of the filters can be flexibly adjusted by tuning the Fermi energy of the graphene waveguide. This ultracompact plasmonic structure contributes to the achievement of frequency division multiplexing systems for optical computing and communications in highly integrated optical circuits.
Method and apparatus for shadow aperture backscatter radiography (SABR) system and protocol
NASA Technical Reports Server (NTRS)
Shedlock, Daniel (Inventor); Jacobs, Alan M. (Inventor); Jacobs, Sharon Auerback (Inventor); Dugan, Edward (Inventor)
2010-01-01
A shadow aperture backscatter radiography (SABR) system includes at least one penetrating radiation source for providing a penetrating radiation field, and at least one partially transmissive radiation detector, wherein the partially transmissive radiation detector is interposed between an object region to be interrogated and the radiation source. The partially transmissive radiation detector transmits a portion of the illumination radiation field. A shadow aperture having a plurality of radiation attenuating regions having apertures therebetween is disposed between the radiation source and the detector. The apertures provide illumination regions for the illumination radiation field to reach the object region, wherein backscattered radiation from the object is detected and generates an image by the detector in regions of the detector that are shadowed by the radiation attenuation regions.
Filter-Based Phase Shifts Distort Neuronal Timing Information.
Yael, Dorin; Vecht, Jacob J; Bar-Gad, Izhar
2018-01-01
Filters are widely used for the modulation, typically attenuation, of amplitudes of different frequencies within neurophysiological signals. Filters, however, also induce changes in the phases of different frequencies whose amplitude is unmodulated. These phase shifts cause time lags in the filtered signals, leading to a disruption of the timing information between different frequencies within the same signal and between different signals. The emerging time lags can be either constant in the case of linear phase (LP) filters or vary as a function of the frequency in the more common case of non-LP (NLP) filters. Since filters are used ubiquitously online in the early stages of data acquisition, the vast majority of neurophysiological signals thus suffer from distortion of the timing information even prior to their sampling. This distortion is often exacerbated by further multiple offline filtering stages of the sampled signal. The distortion of timing information may cause misinterpretation of the results and lead to erroneous conclusions. Here we present a variety of typical examples of filter-induced phase distortions and discuss the evaluation and restoration of the timing information underlying the original signal.
Filter-Based Phase Shifts Distort Neuronal Timing Information
Yael, Dorin; Vecht, Jacob J.
2018-01-01
Filters are widely used for the modulation, typically attenuation, of amplitudes of different frequencies within neurophysiological signals. Filters, however, also induce changes in the phases of different frequencies whose amplitude is unmodulated. These phase shifts cause time lags in the filtered signals, leading to a disruption of the timing information between different frequencies within the same signal and between different signals. The emerging time lags can be either constant in the case of linear phase (LP) filters or vary as a function of the frequency in the more common case of non-LP (NLP) filters. Since filters are used ubiquitously online in the early stages of data acquisition, the vast majority of neurophysiological signals thus suffer from distortion of the timing information even prior to their sampling. This distortion is often exacerbated by further multiple offline filtering stages of the sampled signal. The distortion of timing information may cause misinterpretation of the results and lead to erroneous conclusions. Here we present a variety of typical examples of filter-induced phase distortions and discuss the evaluation and restoration of the timing information underlying the original signal. PMID:29766044
NASA Astrophysics Data System (ADS)
Bellefleur, G.; Riedel, M.; Brent, T.; Wright, F.; Dallimore, S. R.
2007-10-01
Wave attenuation is an important physical property of hydrate-bearing sediments that is rarely taken into account in site characterization with seismic data. We present a field example showing improved images of hydrate-bearing sediments on seismic data after compensation of attenuation effects. Compressional quality factors estimated from zero-offset Vertical Seismic Profiling data acquired at Mallik, Northwest Territories, Canada, demonstrate significant wave attenuation for hydrate-bearing sediments. These results are in agreement with previous attenuation estimates obtained from sonic logs and crosshole data at different frequency intervals. The application of an inverse Q-filter to compensate attenuation effects of permafrost and hydrate-bearing sediments improved the resolution of surface 3D seismic data and its correlation with log data, particularly for the shallowest gas hydrate interval. Compensation of the attenuation effects of the permafrost likely explains most of the improvements for the shallow gas hydrate zone. Our results show that characterization of the Mallik gas hydrates with seismic data not corrected for attenuation would tend to overestimate thicknesses and lateral extent of hydrate-bearing strata and hence, the volume of hydrates in place.
Handling target obscuration through Markov chain observations
NASA Astrophysics Data System (ADS)
Kouritzin, Michael A.; Wu, Biao
2008-04-01
Target Obscuration, including foliage or building obscuration of ground targets and landscape or horizon obscuration of airborne targets, plagues many real world filtering problems. In particular, ground moving target identification Doppler radar, mounted on a surveillance aircraft or unattended airborne vehicle, is used to detect motion consistent with targets of interest. However, these targets try to obscure themselves (at least partially) by, for example, traveling along the edge of a forest or around buildings. This has the effect of creating random blockages in the Doppler radar image that move dynamically and somewhat randomly through this image. Herein, we address tracking problems with target obscuration by building memory into the observations, eschewing the usual corrupted, distorted partial measurement assumptions of filtering in favor of dynamic Markov chain assumptions. In particular, we assume the observations are a Markov chain whose transition probabilities depend upon the signal. The state of the observation Markov chain attempts to depict the current obscuration and the Markov chain dynamics are used to handle the evolution of the partially obscured radar image. Modifications of the classical filtering equations that allow observation memory (in the form of a Markov chain) are given. We use particle filters to estimate the position of the moving targets. Moreover, positive proof-of-concept simulations are included.
NASA Astrophysics Data System (ADS)
Abdalla, M. A.; Choudhary, D. Kumar; Chaudhary, R. Kumar
2018-02-01
This paper presents the design of two reduced size dual-band metamaterial bandpass filters and its simulation followed by measurements of proposed filters. These filters are supporting different frequency bands and primarily could be utilize in radio frequency identification (RFID) application. The filter includes three cells in which two are symmetrical and both inductively coupled with the third cell which is present in between them. In the proposed designs, three different metamaterial composite right/left handed (CRLH) cell resonators have been analysed for compactness. The CRLH cell consists of an interdigital capacitor, a stub/meander line/spiral inductor and a via to connect the top of the structure and ground plane. Finally, the proposed dual band bandpass filters (using meander line and spiral inductor) are showing size reduction by 65% and 50% (with 25% operating frequency reduction), respectively, in comparison with reference filter using stub inductor. More than 30 dB attenuation has been achieved between the two passbands.
Artifact removal from EEG signals using adaptive filters in cascade
NASA Astrophysics Data System (ADS)
Garcés Correa, A.; Laciar, E.; Patiño, H. D.; Valentinuzzi, M. E.
2007-11-01
Artifacts in EEG (electroencephalogram) records are caused by various factors, like line interference, EOG (electro-oculogram) and ECG (electrocardiogram). These noise sources increase the difficulty in analyzing the EEG and to obtaining clinical information. For this reason, it is necessary to design specific filters to decrease such artifacts in EEG records. In this paper, a cascade of three adaptive filters based on a least mean squares (LMS) algorithm is proposed. The first one eliminates line interference, the second adaptive filter removes the ECG artifacts and the last one cancels EOG spikes. Each stage uses a finite impulse response (FIR) filter, which adjusts its coefficients to produce an output similar to the artifacts present in the EEG. The proposed cascade adaptive filter was tested in five real EEG records acquired in polysomnographic studies. In all cases, line-frequency, ECG and EOG artifacts were attenuated. It is concluded that the proposed filter reduces the common artifacts present in EEG signals without removing significant information embedded in these records.
A robust nonlinear filter for image restoration.
Koivunen, V
1995-01-01
A class of nonlinear regression filters based on robust estimation theory is introduced. The goal of the filtering is to recover a high-quality image from degraded observations. Models for desired image structures and contaminating processes are employed, but deviations from strict assumptions are allowed since the assumptions on signal and noise are typically only approximately true. The robustness of filters is usually addressed only in a distributional sense, i.e., the actual error distribution deviates from the nominal one. In this paper, the robustness is considered in a broad sense since the outliers may also be due to inappropriate signal model, or there may be more than one statistical population present in the processing window, causing biased estimates. Two filtering algorithms minimizing a least trimmed squares criterion are provided. The design of the filters is simple since no scale parameters or context-dependent threshold values are required. Experimental results using both real and simulated data are presented. The filters effectively attenuate both impulsive and nonimpulsive noise while recovering the signal structure and preserving interesting details.
Jammed-array wideband sawtooth filter.
Tan, Zhongwei; Wang, Chao; Goda, Keisuke; Malik, Omer; Jalali, Bahram
2011-11-21
We present an all-optical passive low-cost spectral filter that exhibits a high-resolution periodic sawtooth spectral pattern without the need for active optoelectronic components. The principle of the filter is the partial masking of a phased array of virtual light sources with multiply jammed diffraction orders. We utilize the filter's periodic linear map between frequency and intensity to demonstrate fast sensitive interrogation of fiber Bragg grating sensor arrays and ultrahigh-frequency electrical sawtooth waveform generation. © 2011 Optical Society of America
A Compact Band-Pass Filter with High Selectivity and Second Harmonic Suppression
Hadarig, Ramona Cosmina; de Cos Gomez, Maria Elena; Las-Heras, Fernando
2013-01-01
The design of a novel band-pass filter with narrow-band features based on an electromagnetic resonator at 6.4 GHz is presented. A prototype is manufactured and characterized in terms of transmission and reflection coefficient. The selective passband and suppression of the second harmonic make the filter suitable to be used in a C band frequency range for radar systems and satellite/terrestrial applications. To avoid substantial interference for this kind of applications, passive components with narrow band features and small dimensions are required. Between 3.6 GHz and 4.2 GHz the band-pass filter with harmonic suppression should have an attenuation of at least 35 dB, whereas for a passband, less than 10% is sufficient. PMID:28788412
Embolectomy of a Bird's Nest Vena Caval Filter.
Chitwood, W R; Chiang, K S; Williams, J M; Zeri, R S; Semer, D A
1994-12-01
In this case report we describe a successful embolectomy of a partially migrated Bird's Nest Caval Filter with attached embolic material. We used transesophageal echocardiography to guide the surgical approach. The patient recovered uneventfully from both the embolectomy and the subsequent pelvic operation.
Fabrication of a Cryogenic Bias Filter for Ultrasensitive Focal Plane
NASA Technical Reports Server (NTRS)
Chervenak, James; Wollack, Edward
2012-01-01
A fabrication process has been developed for cryogenic in-line filtering for the bias and readout of ultrasensitive cryogenic bolometers for millimeter and submillimeter wavelengths. The design is a microstripline filter that cuts out, or strongly attenuates, frequencies (10 50 GHz) that can be carried by wiring staged at cryogenic temperatures. The filter must have 100-percent transmission at DC and low frequencies where the bias and readout lines will carry signal. The fabrication requires the encapsulation of superconducting wiring in a dielectric-metal envelope with precise electrical characteristics. Sufficiently thick insulation layers with high-conductivity metal layers fully surrounding a patterned superconducting wire in arrayable formats have been demonstrated. A degenerately doped silicon wafer has been chosen to provide a metallic ground plane. A metallic seed layer is patterned to enable attachment to the ground plane. Thick silicon dioxide films are deposited at low temperatures to provide tunable dielectric isolation without degrading the metallic seed layer. Superconducting wiring is deposited and patterned using microstripline filtering techniques to cut out the relevant frequencies. A low Tc superconductor is used so that it will attenuate power strongly above the gap frequency. Thick dielectric is deposited on top of the circuit, and then vias are patterned through both dielectric layers. A thick conductive film is deposited conformally over the entire circuit, except for the contact pads for the signal and bias attachments to complete the encapsulating ground plane. Filters are high-aspect- ratio rectangles, allowing close packing in one direction, while enabling the chip to feed through the wall of a copper enclosure. The chip is secured in the copper wall using a soft metal seal to make good thermal and electrical contact to the outer shield.
Evaluation of Low-Pressure Drop Antimicrobial and Hybrid Air Filters
2006-09-01
purification of aerosol- contaminated air streams has been performed by mechanical filtration. Existing particle filters will stop bacterial and viral...or hybrid low-∆P antimicrobial particulate filter materials. 1.2 Background Traditional purification of aerosol- contaminated air streams has...Plastics, Lima , Ohio). Each path runs through a test article and thence through one AGI-30 all-glass impinger (Chemglass, Vineland, N.J.) partially
Particle Filtering with Region-based Matching for Tracking of Partially Occluded and Scaled Targets*
Nakhmani, Arie; Tannenbaum, Allen
2012-01-01
Visual tracking of arbitrary targets in clutter is important for a wide range of military and civilian applications. We propose a general framework for the tracking of scaled and partially occluded targets, which do not necessarily have prominent features. The algorithm proposed in the present paper utilizes a modified normalized cross-correlation as the likelihood for a particle filter. The algorithm divides the template, selected by the user in the first video frame, into numerous patches. The matching process of these patches by particle filtering allows one to handle the target’s occlusions and scaling. Experimental results with fixed rectangular templates show that the method is reliable for videos with nonstationary, noisy, and cluttered background, and provides accurate trajectories in cases of target translation, scaling, and occlusion. PMID:22506088
A real-time chirp-coded imaging system with tissue attenuation compensation.
Ramalli, A; Guidi, F; Boni, E; Tortoli, P
2015-07-01
In ultrasound imaging, pulse compression methods based on the transmission (TX) of long coded pulses and matched receive filtering can be used to improve the penetration depth while preserving the axial resolution (coded-imaging). The performance of most of these methods is affected by the frequency dependent attenuation of tissue, which causes mismatch of the receiver filter. This, together with the involved additional computational load, has probably so far limited the implementation of pulse compression methods in real-time imaging systems. In this paper, a real-time low-computational-cost coded-imaging system operating on the beamformed and demodulated data received by a linear array probe is presented. The system has been implemented by extending the firmware and the software of the ULA-OP research platform. In particular, pulse compression is performed by exploiting the computational resources of a single digital signal processor. Each image line is produced in less than 20 μs, so that, e.g., 192-line frames can be generated at up to 200 fps. Although the system may work with a large class of codes, this paper has been focused on the test of linear frequency modulated chirps. The new system has been used to experimentally investigate the effects of tissue attenuation so that the design of the receive compression filter can be accordingly guided. Tests made with different chirp signals confirm that, although the attainable compression gain in attenuating media is lower than the theoretical value expected for a given TX Time-Bandwidth product (BT), good SNR gains can be obtained. For example, by using a chirp signal having BT=19, a 13 dB compression gain has been measured. By adapting the frequency band of the receiver to the band of the received echo, the signal-to-noise ratio and the penetration depth have been further increased, as shown by real-time tests conducted on phantoms and in vivo. In particular, a 2.7 dB SNR increase has been measured through a novel attenuation compensation scheme, which only requires to shift the demodulation frequency by 1 MHz. The proposed method characterizes for its simplicity and easy implementation. Copyright © 2015 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Retzlaff, W.A.; Williams, L.E.; DeJong, T.M.
1997-05-01
Nursery stock of plum (Prunus salicina Lindel., cv. Casselman) was planted 1 Apr. 1988 in an experimental orchard at the Univ. of California Kearney Agricultural Center near Fresno, CA. Trees in this study were enclosed in open-top fumigation chambers on 1 May 1989, and exposed to three atmospheric ozone partial pressures (charcoal filtered air, ambient air, and ambient air + ozone) during the 1989 through 1992 growing seasons (typically 1 Apr. - 1 Nov.). A nonchamber treatment plot was used to assess chamber effects on tree performance. This study details the results of the exposures during the initial commercial bearingmore » period (1991 through 1993) in this orchard. The mean 12-h (0800-2000 h Pacific Daylight Time [PDT]) ozone partial pressures during the experimental periods in the charcoal filtered, ambient, ambient + ozone, and nonchamber treatments averaged 0.031, 0.048, 0.091, and 0.056 {mu}Pa Pa{sup {minus}1} in 1991 and 1992, respectively. Fruit number per tree decreased as atmospheric ozone partial pressure increased from the charcoal filtered to ambient + ozone treatment, significantly affecting yield. Yield of plum trees averaged 23.6, 19.8, 13.7, and 17.9 kg tree{sup {minus}1} in 1991 and 1992 in the charcoal filtered, ambient, ambient + ozone, and nonchamber treatments, respectively. Only one out of the five original treatment plots was exposed to ozone treatments during the 1993 growing season. Yield of plum trees in this single replicate in 1993 was reduced by increased atmospheric ozone partial pressure. Yield of plum trees in the four remaining unexposed treatment plots in 1993 was 16.7, 17.9, and 16.0 kg tree{sup {minus}1} in the previous charcoal filtered, ambient, and ambient + ozone treatments respectively. The similarity in yield of the post-chamber treatments indicates that a change in air quality in the current growing season can affect yield of Casselman plum trees. 26 refs., 6 figs., 4 tabs.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kamezawa, H; Fujimoto General Hospital, Miyakonojo, Miyazaki; Arimura, H
Purpose: To investigate the possibility of exposure dose reduction of the cone-beam computed tomography (CBCT) in an image guided patient positioning system by using 6 noise suppression filters. Methods: First, a reference dose (RD) and low-dose (LD)-CBCT (X-ray volume imaging system, Elekta Co.) images were acquired with a reference dose of 86.2 mGy (weighted CT dose index: CTDIw) and various low doses of 1.4 to 43.1 mGy, respectively. Second, an automated rigid registration for three axes was performed for estimating setup errors between a planning CT image and the LD-CBCT images, which were processed by 6 noise suppression filters, i.e.,more » averaging filter (AF), median filter (MF), Gaussian filter (GF), bilateral filter (BF), edge preserving smoothing filter (EPF) and adaptive partial median filter (AMF). Third, residual errors representing the patient positioning accuracy were calculated as an Euclidean distance between the setup error vectors estimated using the LD-CBCT image and RD-CBCT image. Finally, the relationships between the residual error and CTDIw were obtained for 6 noise suppression filters, and then the CTDIw for LD-CBCT images processed by the noise suppression filters were measured at the same residual error, which was obtained with the RD-CBCT. This approach was applied to an anthropomorphic pelvic phantom and two cancer patients. Results: For the phantom, the exposure dose could be reduced from 61% (GF) to 78% (AMF) by applying the noise suppression filters to the CBCT images. The exposure dose in a prostate cancer case could be reduced from 8% (AF) to 61% (AMF), and the exposure dose in a lung cancer case could be reduced from 9% (AF) to 37% (AMF). Conclusion: Using noise suppression filters, particularly an adaptive partial median filter, could be feasible to decrease the additional exposure dose to patients in image guided patient positioning systems.« less
Blough, M M; Waggener, R G; Payne, W H; Terry, J A
1998-09-01
A model for calculating mammographic spectra independent of measured data and fitting parameters is presented. This model is based on first principles. Spectra were calculated using various target and filter combinations such as molybdenum/molybdenum, molybdenum/rhodium, rhodium/rhodium, and tungsten/aluminum. Once the spectra were calculated, attenuation curves were calculated and compared to measured attenuation curves. The attenuation curves were calculated and measured using aluminum alloy 1100 or high purity aluminum filtration. Percent differences were computed between the measured and calculated attenuation curves resulting in an average of 5.21% difference for tungsten/aluminum, 2.26% for molybdenum/molybdenum, 3.35% for rhodium/rhodium, and 3.18% for molybdenum/rhodium. Calculated spectra were also compared to measured spectra from the Food and Drug Administration [Fewell and Shuping, Handbook of Mammographic X-ray Spectra (U.S. Government Printing Office, Washington, D.C., 1979)] and a comparison will also be presented.
SU-F-T-283: A Novel Device to Enable Portal Dosimetry for Flattening Filter Free Beams
DOE Office of Scientific and Technical Information (OSTI.GOV)
Faught, A; Wu, Q; Adamson, J
Purpose: Varian’s electronic portal imaging device (EPID) based portal dosimetry tool is a popular and effective means of performing IMRT QA. EPIDs for older models of the TrueBeam accelerator utilize a 40cmx30cm Image Detection Unit (IDU) that saturates at the center for standard source to imager distances with high dose rate flattening filter free (FFF) beams. This makes portal dosimetry not possible and an alternative means of IMRT QA necessary. We developed a filter that would attenuate the beam to a dose rate measureable by the IDU for portal dosimetry IMRT QA. Methods: Multipurpose 304 stainless steel plates were placedmore » on an accessory tray to attenuate the beam. Profiles of an open field measured on the IDU were acquired with varying number of plates to assess the thickness needed to reduce the maximum dose rates of 6XFFF and 10XFFF beams to measurable levels. A new portal dose image prediction (PDIP) model was commissioned based on open field measurements with plates in position, and a modified beam profile was input to portal dosimetry calibration at the console to empirically correct for attenuation and scatter. The portal dosimetry tool was used to assess agreement between predicted and measured doses for open 25×25cm{sup 2} fields and intensity modulated fields using 6XFFF and 10XFFF beams. Results: Thicknesses of 2.5cm and 3.8cm of steel were required to reduce the highest dose rates to a measureable level for 6XFFF and 10XFFF, respectively. Gamma analysis using a 3%/3mm relative criterion with the filter in place and using the new PDIP model resulted in 98.2% and 93.6% of pixels passing while intensity modulated fields showed passing rates of 98.2% and 99.0%. Conclusion: Use of the filter allows for portal dosimetry to be used for IMRT QA of FFF plans in place of purchasing a second option for IMRT QA.« less
Black carbon cookstove emissions: A field assessment of 19 stove/fuel combinations
NASA Astrophysics Data System (ADS)
Garland, Charity; Delapena, Samantha; Prasad, Rajendra; L'Orange, Christian; Alexander, Donee; Johnson, Michael
2017-11-01
Black carbon (BC) emissions from household cookstoves consuming solid fuel produce approximately 25 percent of total anthropogenic BC emissions. The short atmospheric lifetime of BC means that reducing BC emissions would result in a faster climate response than mitigating CO2 and other long-lived greenhouse gases. This study presents the results of optical BC measurements of two new cookstove emissions field assessments and 17 archived cookstove datasets. BC was determined from attenuation of 880 nm light, which is strongly absorbed by BC, and linearly related between 1 and 125 attenuation units. A relationship was experimentally determined correlating BC mass deposition on quartz filters determined via thermal optical analysis (TOA) and on PTFE and quartz filters using transmissometry, yielding an attenuation cross-section (σATN) for both filter media types. σATN relates TOA measurements to optical measurements on PTFE and quartz (σATN(PTFE) = 13.7 cm-2 μg, R2 = 0.87, σATN(Quartz) = 15.6 cm-2 μg, R2 = 0.87). These filter-specific σATN, optical measurements of archived filters were used to determine BC emission factors and the fraction of particulate matter (PM) in the form of black carbon (BC/PM). The 19 stoves measured fell into five stove classes; simple wood, rocket, advanced biomass, simple charcoal, and advanced charcoal. Advanced biomass stoves include forced- and natural-draft gasifiers which use wood or biomass pellets as fuel. Of these classes, the simple wood and rocket stoves demonstrated the highest median BC emission factors, ranging from 0.051 to 0.14 g MJ-1. The lowest BC emission factors were seen in charcoal stoves, which corresponds to the generally low PM emission factors observed during charcoal combustion, ranging from 0.0084 to 0.014 g MJ-1. The advanced biomass stoves generally showed an improvement in BC emissions factors compared to simple wood and rocket stoves, ranging from 0.0031 to 0.071 g MJ-1. BC/PM ratios were highest for the advanced and rocket stoves. Potential relative climate impacts were estimated by converting aerosol emissions to CO2-equivalent, and suggest that some advanced stove/fuel combinations could provide substantial climate benefits.
Symmetric/Asymmetrical SIRs Dual-Band BPF Design for WLAN Applications
NASA Astrophysics Data System (ADS)
Ho, Min-Hua; Ho, Hao-Hung; Chen, Mingchih
This paper presents the dual-band bandpass filters (BPFs) design composed of λ/2 and symmetrically/asymmetrically paired λ/4 stepped impedance resonators (SIRs) for the WLAN applications. The filters cover both the operating frequencies of 2.45 and 5.2GHz. The dual-coupling mechanism is used in the filter design to provide alternative routes for signals of selected frequencies. A prototype filter is composed of λ/2 and symmetrical λ/4 SIRs. The enhanced wide-stopband filter is then developed from the filter with the symmetrical λ/4 SIRs replaced by the asymmetrical ones. The asymmetrical λ/4 SIRs have their higher resonances frequencies isolated from the adjacent I/O SIRs and extend the enhanced filter an upper stopband limit beyond ten time the fundamental frequency. Also, the filter might possess a cross-coupling structure which introduces transmission zeros by the passband edges to improve the signal selectivity. The tapped-line feed is adopted in this circuit to create additional attenuation poles for improving the stopband rejection levels. Experiments are conducted to verify the circuit performance.
Single and tandem Fabry-Perot etalons as solar background filters for lidar.
McKay, J A
1999-09-20
Atmospheric lidar is difficult in daylight because of sunlight scattered into the receiver field of view. In this research methods for the design and performance analysis of Fabry-Perot etalons as solar background filters are presented. The factor by which the signal to background ratio is enhanced is defined as a measure of the performance of the etalon as a filter. Equations for evaluating this parameter are presented for single-, double-, and triple-etalon filter systems. The role of reflective coupling between etalons is examined and shown to substantially reduce the contributions of the second and third etalons to the filter performance. Attenuators placed between the etalons can improve the filter performance, at modest cost to the signal transmittance. The principal parameter governing the performance of the etalon filters is the etalon defect finesse. Practical limitations on etalon plate smoothness and parallelism cause the defect finesse to be relatively low, especially in the ultraviolet, and this sets upper limits to the capability of tandem etalon filters to suppress the solar background at tolerable cost to the signal.
Assessment of female breast dose for thoracic cone-beam CT using MOSFET dosimeters.
Sun, Wenzhao; Wang, Bin; Qiu, Bo; Liang, Jian; Xie, Weihao; Deng, Xiaowu; Qi, Zhenyu
2017-03-21
To assess the breast dose during a routine thoracic cone-beam CT (CBCT) check with the efforts to explore the possible dose reduction strategy. Metal oxide semiconductor field-effect transistor (MOSFET) dosimeters were used to measure breast surface doses during a thorax kV CBCT scan in an anthropomorphic phantom. Breast doses for different scanning protocols and breast sizes were compared. Dose reduction was attempted by using partial arc CBCT scan with bowtie filter. The impact of this dose reduction strategy on image registration accuracy was investigated. The average breast surface doses were 20.02 mGy and 11.65 mGy for thoracic CBCT without filtration and with filtration, respectively. This indicates a dose reduction of 41.8% by use of bowtie filter. It was found 220° partial arc scanning significantly reduced the dose to contralateral breast (44.4% lower than ipsilateral breast), while the image registration accuracy was not compromised. Breast dose reduction can be achieved by using ipsilateral 220° partial arc scan with bowtie filter. This strategy also provides sufficient image quality for thorax image registration in daily patient positioning verification.
Impact of pre-imputation SNP-filtering on genotype imputation results
2014-01-01
Background Imputation of partially missing or unobserved genotypes is an indispensable tool for SNP data analyses. However, research and understanding of the impact of initial SNP-data quality control on imputation results is still limited. In this paper, we aim to evaluate the effect of different strategies of pre-imputation quality filtering on the performance of the widely used imputation algorithms MaCH and IMPUTE. Results We considered three scenarios: imputation of partially missing genotypes with usage of an external reference panel, without usage of an external reference panel, as well as imputation of completely un-typed SNPs using an external reference panel. We first created various datasets applying different SNP quality filters and masking certain percentages of randomly selected high-quality SNPs. We imputed these SNPs and compared the results between the different filtering scenarios by using established and newly proposed measures of imputation quality. While the established measures assess certainty of imputation results, our newly proposed measures focus on the agreement with true genotypes. These measures showed that pre-imputation SNP-filtering might be detrimental regarding imputation quality. Moreover, the strongest drivers of imputation quality were in general the burden of missingness and the number of SNPs used for imputation. We also found that using a reference panel always improves imputation quality of partially missing genotypes. MaCH performed slightly better than IMPUTE2 in most of our scenarios. Again, these results were more pronounced when using our newly defined measures of imputation quality. Conclusion Even a moderate filtering has a detrimental effect on the imputation quality. Therefore little or no SNP filtering prior to imputation appears to be the best strategy for imputing small to moderately sized datasets. Our results also showed that for these datasets, MaCH performs slightly better than IMPUTE2 in most scenarios at the cost of increased computing time. PMID:25112433
Orbit Determination Using Vinti’s Solution
2016-09-15
Surveillance Network STK Systems Tool Kit TBP Two Body Problem TLE Two-line Element Set xv Acronym Definition UKF Unscented Kalman Filter WPAFB Wright...simplicity, stability, and speed. On the other hand, Kalman filters would be best suited for sequential estimation of stochastic or random components of a...be likened to how an Unscented Kalman Filter samples a system’s nonlinearities directly, avoiding linearizing the dynamics in the partials matrices
Characterization of Filters Loaded With Reactor Strontium Carbonate - 13203
DOE Office of Scientific and Technical Information (OSTI.GOV)
Josephson, Walter S.; Steen, Franciska H.
A collection of three highly radioactive filters containing reactor strontium carbonate were being prepared for disposal. All three filters were approximately characterized at the time of manufacture by gravimetric methods. The first filter had been partially emptied, and the quantity of residual activity was uncertain. Dose rate to activity modeling using the Monte-Carlo N Particle (MCNP) code was selected to confirm the gravimetric characterization of the full filters, and to fully characterize the partially emptied filter. Although dose rate to activity modeling using MCNP is a common technique, it is not often used for Bremsstrahlung-dominant materials such as reactor strontium.more » As a result, different MCNP modeling options were compared to determine the optimum approach. This comparison indicated that the accuracy of the results were heavily dependent on the MCNP modeling details and the location of the dose rate measurement point. The optimum model utilized a photon spectrum generated by the Oak Ridge Isotope Generation and Depletion (ORIGEN) code and dose rates measured at 30 cm. Results from the optimum model agreed with the gravimetric estimates within 15%. It was demonstrated that dose rate to activity modeling can be successful for Bremsstrahlung-dominant radioactive materials. However, the degree of success is heavily dependent on the choice of modeling techniques. (authors)« less
Information-Efficient Spectral Imaging Sensor With Tdi
Rienstra, Jeffrey L.; Gentry, Stephen M.; Sweatt, William C.
2004-01-13
A programmable optical filter for use in multispectral and hyperspectral imaging employing variable gain time delay and integrate arrays. A telescope focuses an image of a scene onto at least one TDI array that is covered by a multispectral filter that passes separate bandwidths of light onto the rows in the TDI array. The variable gain feature of the TDI array allows individual rows of pixels to be attenuated individually. The attenuations are functions of the magnitudes of the positive and negative components of a spectral basis vector. The spectral basis vector is constructed so that its positive elements emphasize the presence of a target and its negative elements emphasize the presence of the constituents of the background of the imaged scene. This system provides for a very efficient determination of the presence of the target, as opposed to the very data intensive data manipulations that are required in conventional hyperspectral imaging systems.
Time-frequency domain SNR estimation and its application in seismic data processing
NASA Astrophysics Data System (ADS)
Zhao, Yan; Liu, Yang; Li, Xuxuan; Jiang, Nansen
2014-08-01
Based on an approach estimating frequency domain signal-to-noise ratio (FSNR), we propose a method to evaluate time-frequency domain signal-to-noise ratio (TFSNR). This method adopts short-time Fourier transform (STFT) to estimate instantaneous power spectrum of signal and noise, and thus uses their ratio to compute TFSNR. Unlike FSNR describing the variation of SNR with frequency only, TFSNR depicts the variation of SNR with time and frequency, and thus better handles non-stationary seismic data. By considering TFSNR, we develop methods to improve the effects of inverse Q filtering and high frequency noise attenuation in seismic data processing. Inverse Q filtering considering TFSNR can better solve the problem of amplitude amplification of noise. The high frequency noise attenuation method considering TFSNR, different from other de-noising methods, distinguishes and suppresses noise using an explicit criterion. Examples of synthetic and real seismic data illustrate the correctness and effectiveness of the proposed methods.
Fieselmann, Andreas; Dennerlein, Frank; Deuerling-Zheng, Yu; Boese, Jan; Fahrig, Rebecca; Hornegger, Joachim
2011-06-21
Filtered backprojection is the basis for many CT reconstruction tasks. It assumes constant attenuation values of the object during the acquisition of the projection data. Reconstruction artifacts can arise if this assumption is violated. For example, contrast flow in perfusion imaging with C-arm CT systems, which have acquisition times of several seconds per C-arm rotation, can cause this violation. In this paper, we derived and validated a novel spatio-temporal model to describe these kinds of artifacts. The model separates the temporal dynamics due to contrast flow from the scan and reconstruction parameters. We introduced derivative-weighted point spread functions to describe the spatial spread of the artifacts. The model allows prediction of reconstruction artifacts for given temporal dynamics of the attenuation values. Furthermore, it can be used to systematically investigate the influence of different reconstruction parameters on the artifacts. We have shown that with optimized redundancy weighting function parameters the spatial spread of the artifacts around a typical arterial vessel can be reduced by about 70%. Finally, an inversion of our model could be used as the basis for novel dynamic reconstruction algorithms that further minimize these artifacts.
Role of astrocytes in reproduction and neuroprotection.
Mahesh, Virendra B; Dhandapani, Krishnan M; Brann, Darrell W
2006-02-26
Hypothalamic astrocytes secrete TGF-beta and 3 alpha,5 alpha-tetrahydro progesterone (3 alpha,5 alpha-THP) in culture. When the astrocyte-conditioned medium (ACM) was incubated with the hypothalamic cell line GT1-7, it resulted in the secretion of GnRH. Immunoneutralization with TGF-beta antibody or ultra-filteration with a 10 kDa cut off filter resulted in attenuation of the GnRH releasing ability of ACM, indicating that TGF-beta was a major factor involved with GnRH release. Treatment with estrogens increases TGF-beta secretion. These observations indicate a significant role of astrocytes in GnRH secretion. Serum-deprivation results in the death of GT1-7 neurons in culture and addition of ACM or TGF-beta to the culture, attenuates cell death. The mechanism of protection from cell death appears to involve phosphorylation of MKK4, JNK, c-Jun(Ser63), and enhancement of AP-1 binding. Co-administration of JNK inhibitors, but not MEK inhibitors attenuated ACM or TGF-beta-induced c-Jun(Ser63) phosphorylation and their neuroprotective effects. These studies suggest that astrocytes can protect neurons, at least in part, by the release of TGF-beta and activation of a c-Jun/AP-1 protective pathway.
H∞ filter design for nonlinear systems with quantised measurements in finite frequency domain
NASA Astrophysics Data System (ADS)
El Hellani, D.; El Hajjaji, A.; Ceschi, R.
2017-04-01
This paper deals with the problem of finite frequency (FF) H∞ full-order fuzzy filter design for nonlinear discrete-time systems with quantised measurements, described by Takagi-Sugeno models. The measured signals are assumed to be quantised with a logarithmic quantiser. Using a fuzzy-basis-dependent Lyapunov function, the finite frequency ℓ2 gain definition, the generalised S-procedure, and Finsler's lemma, a set of sufficient conditions are established in terms of matrix inequalities, ensuring that the filtering error system is stable and the H∞ attenuation level, from disturbance to the estimation error, is smaller than a given value over a prescribed finite frequency domain of the external disturbances. With the aid of Finsler's lemma, a large number of slack variables are introduced to the design conditions, which provides extra degrees of freedom in optimising the guaranteed H∞ performance. This directly leads to performance improvement and reduction of conservatism. Finally, we give a simulation example to demonstrate the efficiency of the proposed design method, and we show that a lower H∞ attenuation level can be obtained by our developed approach in comparison with another result in the literature.
Partial information decomposition as a spatiotemporal filter.
Flecker, Benjamin; Alford, Wesley; Beggs, John M; Williams, Paul L; Beer, Randall D
2011-09-01
Understanding the mechanisms of distributed computation in cellular automata requires techniques for characterizing the emergent structures that underlie information processing in such systems. Recently, techniques from information theory have been brought to bear on this problem. Building on this work, we utilize the new technique of partial information decomposition to show that previous information-theoretic measures can confound distinct sources of information. We then propose a new set of filters and demonstrate that they more cleanly separate out the background domains, particles, and collisions that are typically associated with information storage, transfer, and modification in cellular automata.
A digital matched filter for reverse time chaos.
Bailey, J Phillip; Beal, Aubrey N; Dean, Robert N; Hamilton, Michael C
2016-07-01
The use of reverse time chaos allows the realization of hardware chaotic systems that can operate at speeds equivalent to existing state of the art while requiring significantly less complex circuitry. Matched filter decoding is possible for the reverse time system since it exhibits a closed form solution formed partially by a linear basis pulse. Coefficients have been calculated and are used to realize the matched filter digitally as a finite impulse response filter. Numerical simulations confirm that this correctly implements a matched filter that can be used for detection of the chaotic signal. In addition, the direct form of the filter has been implemented in hardware description language and demonstrates performance in agreement with numerical results.
A digital matched filter for reverse time chaos
NASA Astrophysics Data System (ADS)
Bailey, J. Phillip; Beal, Aubrey N.; Dean, Robert N.; Hamilton, Michael C.
2016-07-01
The use of reverse time chaos allows the realization of hardware chaotic systems that can operate at speeds equivalent to existing state of the art while requiring significantly less complex circuitry. Matched filter decoding is possible for the reverse time system since it exhibits a closed form solution formed partially by a linear basis pulse. Coefficients have been calculated and are used to realize the matched filter digitally as a finite impulse response filter. Numerical simulations confirm that this correctly implements a matched filter that can be used for detection of the chaotic signal. In addition, the direct form of the filter has been implemented in hardware description language and demonstrates performance in agreement with numerical results.
A Source Term for Wave Attenuation by Sea Ice in WAVEWATCH III(registered trademark): IC4
2017-06-07
energy in the high frequency face of the spectrum, which highlights the fact that frequency dependent attenuation in necessary to replicate the low-pass... frequency space ; M6) and an expanded version of M5 with up to 10 steps. The remainder of this report is structured as follows: a note about the...function period, T = 1/f. Measurements have shown that ice preferentially damps high frequency waves and in this way ice acts as a low pass filter
NASA Astrophysics Data System (ADS)
Barrière, J.; Sénéchal, P.; Bordes, C.; Perroud, H.
2010-12-01
Nowadays, it is well known that hydrogeological properties of the porous media (porosity, fluid saturation and permeability) can influence seismic properties. The major theory which links hydrogeological and seismic parameters is poroelasticity proposed by Biot (1956) for saturated porous media in a wetting phase fluid. However the Biot relaxation process can't explain the level of attenuation of seismic waves generally measured on field from seismic to sonic frequency range in the case of partially saturated media. Laboratory experiments are necessary to better understand the effects of fluids on the attenuation of waves but few ones are done in the low frequency range (1Hz to 10 kHz) where the wavelength is greater than heterogeneities size. We propose an experimental study to determine the attenuation of propagative P-wave in the sonic frequency range on unconsolidated and partially saturated porous media, typical of near surface hydrogeological media. 10 accelerometers (0.0001-17kHz) and 6 capacitance probes (soil moisture sensors) are placed in a container (107 cm x 34 cm x 35cm) full of homogeneous sand (99% silica). An acoustic source (0 - 20 kHz) generate seismic waves which are recorded by the accelerometers during three cycles of imbibition-drainage (corresponding to a water saturation range from 0% to 95%). Values of attenuation (quality factor Q) versus water saturation and frequency are calculated with the well-known spectral ratio method. The spectrum of each recorded P-wave is obtained by a continuous wavelet transform, more adapted than Fourier transform for a non-stationary signal, such as seismic signal, whose frequency content varies with time. The first analyses show a strong dependence of the quality factor with frequency and water saturation, notably at high water saturation (above 60 %) where the attenuation is maximum. Knowing some important parameters of the studied media such as porosity and permeability, we interpret physically our results in accordance with some recent poroelastic models.
Multisource least-squares reverse-time migration with structure-oriented filtering
NASA Astrophysics Data System (ADS)
Fan, Jing-Wen; Li, Zhen-Chun; Zhang, Kai; Zhang, Min; Liu, Xue-Tong
2016-09-01
The technology of simultaneous-source acquisition of seismic data excited by several sources can significantly improve the data collection efficiency. However, direct imaging of simultaneous-source data or blended data may introduce crosstalk noise and affect the imaging quality. To address this problem, we introduce a structure-oriented filtering operator as preconditioner into the multisource least-squares reverse-time migration (LSRTM). The structure-oriented filtering operator is a nonstationary filter along structural trends that suppresses crosstalk noise while maintaining structural information. The proposed method uses the conjugate-gradient method to minimize the mismatch between predicted and observed data, while effectively attenuating the interference noise caused by exciting several sources simultaneously. Numerical experiments using synthetic data suggest that the proposed method can suppress the crosstalk noise and produce highly accurate images.
Evaluation of a new breast-shaped compensation filter for a newly built breast imaging system
NASA Astrophysics Data System (ADS)
Cai, Weixing; Ning, Ruola; Zhang, Yan; Conover, David
2007-03-01
A new breast-shaped compensation filter has been designed and fabricated for breast imaging using our newly built breast imaging (CBCTBI) system, which is able to scan an uncompressed breast with pendant geometry. The shape of this compensation filter is designed based on an average-sized breast phantom. Unlike conventional bow-tie compensation filters, its cross-sectional profile varies along the chest wall-to-nipple direction for better compensation for the shape of a breast. Breast phantoms of three different sizes are used to evaluate the performance of this compensation filter. The reconstruction image quality was studied and compared to that obtained without the compensation filter in place. The uniformity of linear attenuation coefficient and the uniformity of noise distribution are significantly improved, and the contrast-to-noise ratios (CNR) of small lesions near the chest wall are increased as well. Multi-normal image method is used in the reconstruction process to correct compensation flood field and to reduce ring artifacts.
Low pass filter for plasma discharge
Miller, Paul A.
1994-01-01
An isolator is disposed between a plasma reactor and its electrical energy source in order to isolate the reactor from the electrical energy source. The isolator operates as a filter to attenuate the transmission of harmonics of a fundamental frequency of the electrical energy source generated by the reactor from interacting with the energy source. By preventing harmonic interaction with the energy source, plasma conditions can be readily reproduced independent of the electrical characteristics of the electrical energy source and/or its associated coupling network.
Filter Enhances Fluorescent-Penetrant-Inspecting Borescope
NASA Technical Reports Server (NTRS)
Molina, Orlando G.
1990-01-01
Slip-on eyepiece for commercial ultraviolet-light borescope reduces both amount of short-wave ultraviolet light that reaches viewer's eye and apparent intensity of unwanted reflections of white light from surfaces undergoing inspection. Fits on stock eyepiece of borescope, which illuminates surface inspected with intense ultraviolet light. Surface, which is treated with fluorescent dye, emits bright-green visible light wherever dye penetrates - in cracks and voids. Eyepiece contains deep-yellow Wratten 15 (G) filter, which attenuates unwanted light strongly but passes yellow-green fluorescence so defects seen clearly.
NASA Astrophysics Data System (ADS)
Tzanis, Andreas
2013-02-01
The Ground Probing Radar (GPR) is a valuable tool for near surface geological, geotechnical, engineering, environmental, archaeological and other work. GPR images of the subsurface frequently contain geometric information (constant or variable-dip reflections) from various structures such as bedding, cracks, fractures, etc. Such features are frequently the target of the survey; however, they are usually not good reflectors and they are highly localized in time and in space. Their scale is therefore a factor significantly affecting their detectability. At the same time, the GPR method is very sensitive to broadband noise from buried small objects, electromagnetic anthropogenic activity and systemic factors, which frequently blurs the reflections from such targets. This paper introduces a method to de-noise GPR data and extract geometric information from scale-and-dip dependent structural features, based on one-dimensional B-Spline Wavelets, two-dimensional directional B-Spline Wavelet (BSW) Filters and two-dimensional Gabor Filters. A directional BSW Filter is built by sidewise arranging s identical one-dimensional wavelets of length L, tapering the s-parallel direction (span) with a suitable window function and rotating the resulting matrix to the desired orientation. The length L of the wavelet defines the temporal and spatial scale to be isolated and the span determines the length over which to smooth (spatial resolution). The Gabor Filter is generated by multiplying an elliptical Gaussian by a complex plane wave; at any orientation the temporal or spatial scale(s) to be isolated are determined by the wavelength. λ of the plane wave and the spatial resolution by the spatial aspect ratio γ, which specifies the ellipticity of the support of the Gabor function. At any orientation, both types of filter may be tuned at any frequency or spatial wavenumber by varying the length or the wavelength respectively. The filters can be applied directly to two-dimensional radargrams, in which case they abstract information about given scales at given orientations. Alternatively, they can be rotated to different orientations under adaptive control, so that they remain tuned at a given frequency or wavenumber and the resulting images can be stacked in the LS sense, so as to obtain a complete representation of the input data at a given temporal or spatial scale. In addition to isolating geometrical information for further scrutiny, the proposed filtering methods can be used to enhance the S/N ratio in a manner particularly suitable for GPR data, because the frequency response of the filters mimics the frequency characteristics of the source wavelet. Finally, signal attenuation and temporal localization are closely associated: low attenuation interfaces tend to produce reflections rich in high frequencies and fine-scale localization as a function of time. Conversely, high attenuation interfaces will produce reflections rich in low frequencies and broad localization. Accordingly, the temporal localization characteristics of the filters may be exploited to investigate the characteristics of signal propagation (hence material properties). The method is shown to be very effective in extracting fine to coarse scale information from noisy data and is demonstrated with applications to noisy GPR data from archaeometric and geotechnical surveys.
ERIC Educational Resources Information Center
Nicewander, W. Alan
2018-01-01
Spearman's correction for attenuation (measurement error) corrects a correlation coefficient for measurement errors in either-or-both of two variables, and follows from the assumptions of classical test theory. Spearman's equation removes all measurement error from a correlation coefficient which translates into "increasing the reliability of…
Stochastic Integration H∞ Filter for Rapid Transfer Alignment of INS.
Zhou, Dapeng; Guo, Lei
2017-11-18
The performance of an inertial navigation system (INS) operated on a moving base greatly depends on the accuracy of rapid transfer alignment (RTA). However, in practice, the coexistence of large initial attitude errors and uncertain observation noise statistics poses a great challenge for the estimation accuracy of misalignment angles. This study aims to develop a novel robust nonlinear filter, namely the stochastic integration H ∞ filter (SIH ∞ F) for improving both the accuracy and robustness of RTA. In this new nonlinear H ∞ filter, the stochastic spherical-radial integration rule is incorporated with the framework of the derivative-free H ∞ filter for the first time, and the resulting SIH ∞ F simultaneously attenuates the negative effect in estimations caused by significant nonlinearity and large uncertainty. Comparisons between the SIH ∞ F and previously well-known methodologies are carried out by means of numerical simulation and a van test. The results demonstrate that the newly-proposed method outperforms the cubature H ∞ filter. Moreover, the SIH ∞ F inherits the benefit of the traditional stochastic integration filter, but with more robustness in the presence of uncertainty.
On simplified application of multidimensional Savitzky-Golay filters and differentiators
NASA Astrophysics Data System (ADS)
Shekhar, Chandra
2016-02-01
I propose a simplified approach for multidimensional Savitzky-Golay filtering, to enable its fast and easy implementation in scientific and engineering applications. The proposed method, which is derived from a generalized framework laid out by Thornley (D. J. Thornley, "Novel anisotropic multidimensional convolution filters for derivative estimation and reconstruction" in Proceedings of International Conference on Signal Processing and Communications, November 2007), first transforms any given multidimensional problem into a unique one, by transforming coordinates of the sampled data nodes to unity-spaced, uniform data nodes, and then performs filtering and calculates partial derivatives on the unity-spaced nodes. It is followed by transporting the calculated derivatives back onto the original data nodes by using the chain rule of differentiation. The burden to performing the most cumbersome task, which is to carry out the filtering and to obtain derivatives on the unity-spaced nodes, is almost eliminated by providing convolution coefficients for a number of convolution kernel sizes and polynomial orders, up to four spatial dimensions. With the availability of the convolution coefficients, the task of filtering at a data node reduces merely to multiplication of two known matrices. Simplified strategies to adequately address near-boundary data nodes and to calculate partial derivatives there are also proposed. Finally, the proposed methodologies are applied to a three-dimensional experimentally obtained data set, which shows that multidimensional Savitzky-Golay filters and differentiators perform well in both the internal and the near-boundary regions of the domain.
Losartan corrects abnormal frequency response of renal vasculature in congestive heart failure.
DiBona, Gerald F; Sawin, Linda L
2003-11-01
In congestive heart failure, renal blood flow is decreased and renal vascular resistance is increased in a setting of increased activity of both the sympathetic nervous and renin-angiotensin systems. The renal vasoconstrictor response to renal nerve stimulation is enhanced. This is associated with an abnormality in the low-pass filter function of the renal vasculature wherein higher frequencies (> or =0.01 Hz) within renal sympathetic nerve activity are not normally attenuated and are passed into the renal blood flow signal. This study tested the hypothesis that excess angiotensin II action mediates the abnormal frequency response characteristics of the renal vasculature in congestive heart failure. In anesthetized rats, the renal vasoconstrictor response to graded frequency renal nerve stimulation was significantly greater in congestive heart failure than in control rats. Losartan attenuated the renal vasoconstrictor response to a significantly greater degree in congestive heart failure than in control rats. In control rats, the frequency response of the renal vasculature was that of a first order (-20 dB/frequency decade) low-pass filter with a corner frequency (-3 dB, 30% attenuation) of 0.002 Hz and 97% attenuation (-30 dB) at > or =0.1 Hz. In congestive heart failure rats, attenuation did not exceed 45% (-5 dB) over the frequency range of 0.001-0.6 Hz. The frequency response of the renal vasculature was not affected by losartan treatment in control rats but was completely restored to normal by losartan treatment in congestive heart failure rats. The enhanced renal vasoconstrictor response to renal nerve stimulation and the associated abnormality in the frequency response characteristics of the renal vasculature seen in congestive heart failure are mediated by the action of angiotensin II on renal angiotensin II AT1 receptors.
Heterogeneous MEMS Device Assembly and Integration
2014-04-01
included a camera, a He-Ne laser, attenuation filters, folding mirrors, the micromirror under test (MUT) and the observation plane. The MUT was...non activated mirror (the initial incidence plane) was horizontal. Figure 4: Micromirror characterization setup. The static response of a beam
Fiber Optic Sensor System Using Birefringent Filters For Spectral Encoding
NASA Astrophysics Data System (ADS)
Dorsch, Friedhelm; Ulrich, Reinhard
1989-02-01
A system of multimode fiber optic sensors is described for the remote measurement of position, angle, force, pressure and other measurands that can be converted into a rotation of polarization. A birefringent filter encodes the polarization angle into the power ratio of two interleaved comb spectra or, in a modified implementation, into the absolute spectral position of a comb spectrum. By using identical filters in all transducers and in the evaluation unit, transducers for the same or different measurands become interchange-able. All sensors are of the incremental type, with accuracies reaching 0.5 % of one period of the measurand, independent of variations in the attenuation of the fiber link of up to 20dB.
Kronberg, J.W.
1992-10-20
A viewing device for observing objects in near-infrared false-color comprising a pair of goggles with one or more filters in the apertures, and pads that engage the face for blocking stray light from the sides so that all light reaching the user's eyes come through the filters. The filters attenuate most visible light and pass near-infrared (having wavelengths longer than approximately 700 nm) and a small amount of blue-green and blue-violet (having wavelengths in the 500 to 520 nm and shorter than 435 nm, respectively). The goggles are useful for looking at vegetation to identify different species and for determining the health of the vegetation, and to detect some forms of camouflage. 7 figs.
Kronberg, James W.
1992-01-01
A viewing device for observing objects in near-infrared false-color comprising a pair of goggles with one or more filters in the apertures, and pads that engage the face for blocking stray light from the sides so that all light reaching the user's eyes come through the filters. The filters attenuate most visible light and pass near-infrared (having wavelengths longer than approximately 700 nm) and a small amount of blue-green and blue-violet (having wavelengths in the 500 to 520 nm and shorter than 435 nm, respectively). The goggles are useful for looking at vegetation to identify different species and for determining the health of the vegetation, and to detect some forms of camouflage.
Kronberg, J.W.
1991-05-08
This invention consists of a viewing device for observing objects in near-infrared false-color comprising a pair of goggles with one or more filters in the apertures, and pads that engage the face for blocking stray light from the sides so that all light reaching, the user`s eyes come through the filters. The filters attenuate most visible light and pass near-infrared (having wavelengths longer than approximately 700 nm) and a small amount of blue-green and blue-violet (having wavelengths in the 500 to 520 nm and shorter than 435 nm, respectively). The goggles are useful for looking at vegetation to identify different species and for determining the health of the vegetation, and to detect some forms of camouflage.
Lei, Xusheng; Li, Jingjing
2012-01-01
This paper presents an adaptive information fusion method to improve the accuracy and reliability of the altitude measurement information for small unmanned aerial rotorcraft during the landing process. Focusing on the low measurement performance of sensors mounted on small unmanned aerial rotorcraft, a wavelet filter is applied as a pre-filter to attenuate the high frequency noises in the sensor output. Furthermore, to improve altitude information, an adaptive extended Kalman filter based on a maximum a posteriori criterion is proposed to estimate measurement noise covariance matrix in real time. Finally, the effectiveness of the proposed method is proved by static tests, hovering flight and autonomous landing flight tests. PMID:23201993
A digital matched filter for reverse time chaos
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bailey, J. Phillip, E-mail: mchamilton@auburn.edu; Beal, Aubrey N.; Dean, Robert N.
2016-07-15
The use of reverse time chaos allows the realization of hardware chaotic systems that can operate at speeds equivalent to existing state of the art while requiring significantly less complex circuitry. Matched filter decoding is possible for the reverse time system since it exhibits a closed form solution formed partially by a linear basis pulse. Coefficients have been calculated and are used to realize the matched filter digitally as a finite impulse response filter. Numerical simulations confirm that this correctly implements a matched filter that can be used for detection of the chaotic signal. In addition, the direct form ofmore » the filter has been implemented in hardware description language and demonstrates performance in agreement with numerical results.« less
NASA Astrophysics Data System (ADS)
Desiraju, Naveen Kumar; Doclo, Simon; Wolff, Tobias
2017-12-01
Acoustic echo cancellation (AEC) is a key speech enhancement technology in speech communication and voice-enabled devices. AEC systems employ adaptive filters to estimate the acoustic echo paths between the loudspeakers and the microphone(s). In applications involving surround sound, the computational complexity of an AEC system may become demanding due to the multiple loudspeaker channels and the necessity of using long filters in reverberant environments. In order to reduce the computational complexity, the approach of partially updating the AEC filters is considered in this paper. In particular, we investigate tap selection schemes which exploit the sparsity present in the loudspeaker channels for partially updating subband AEC filters. The potential for exploiting signal sparsity across three dimensions, namely time, frequency, and channels, is analyzed. A thorough analysis of different state-of-the-art tap selection schemes is performed and insights about their limitations are gained. A novel tap selection scheme is proposed which overcomes these limitations by exploiting signal sparsity while not ignoring any filters for update in the different subbands and channels. Extensive simulation results using both artificial as well as real-world multichannel signals show that the proposed tap selection scheme outperforms state-of-the-art tap selection schemes in terms of echo cancellation performance. In addition, it yields almost identical echo cancellation performance as compared to updating all filter taps at a significantly reduced computational cost.
NASA Astrophysics Data System (ADS)
Shams Esfand Abadi, Mohammad; AbbasZadeh Arani, Seyed Ali Asghar
2011-12-01
This paper extends the recently introduced variable step-size (VSS) approach to the family of adaptive filter algorithms. This method uses prior knowledge of the channel impulse response statistic. Accordingly, optimal step-size vector is obtained by minimizing the mean-square deviation (MSD). The presented algorithms are the VSS affine projection algorithm (VSS-APA), the VSS selective partial update NLMS (VSS-SPU-NLMS), the VSS-SPU-APA, and the VSS selective regressor APA (VSS-SR-APA). In VSS-SPU adaptive algorithms the filter coefficients are partially updated which reduce the computational complexity. In VSS-SR-APA, the optimal selection of input regressors is performed during the adaptation. The presented algorithms have good convergence speed, low steady state mean square error (MSE), and low computational complexity features. We demonstrate the good performance of the proposed algorithms through several simulations in system identification scenario.
NASA Astrophysics Data System (ADS)
Hsieh, Scott S.; Pelc, Norbert J.
2014-06-01
Photon counting x-ray detectors (PCXDs) offer several advantages compared to standard energy-integrating x-ray detectors, but also face significant challenges. One key challenge is the high count rates required in CT. At high count rates, PCXDs exhibit count rate loss and show reduced detective quantum efficiency in signal-rich (or high flux) measurements. In order to reduce count rate requirements, a dynamic beam-shaping filter can be used to redistribute flux incident on the patient. We study the piecewise-linear attenuator in conjunction with PCXDs without energy discrimination capabilities. We examined three detector models: the classic nonparalyzable and paralyzable detector models, and a ‘hybrid’ detector model which is a weighted average of the two which approximates an existing, real detector (Taguchi et al 2011 Med. Phys. 38 1089-102 ). We derive analytic expressions for the variance of the CT measurements for these detectors. These expressions are used with raw data estimated from DICOM image files of an abdomen and a thorax to estimate variance in reconstructed images for both the dynamic attenuator and a static beam-shaping (‘bowtie’) filter. By redistributing flux, the dynamic attenuator reduces dose by 40% without increasing peak variance for the ideal detector. For non-ideal PCXDs, the impact of count rate loss is also reduced. The nonparalyzable detector shows little impact from count rate loss, but with the paralyzable model, count rate loss leads to noise streaks that can be controlled with the dynamic attenuator. With the hybrid model, the characteristic count rates required before noise streaks dominate the reconstruction are reduced by a factor of 2 to 3. We conclude that the piecewise-linear attenuator can reduce the count rate requirements of the PCXD in addition to improving dose efficiency. The magnitude of this reduction depends on the detector, with paralyzable detectors showing much greater benefit than nonparalyzable detectors.
Preliminary results on interstellar reddening as deduced from filter photometry
NASA Technical Reports Server (NTRS)
Laget, M.
1972-01-01
Filter photometry has been used to derive the interstellar reddening law from stars through the study of a single spectral type, B0. The deficiency in the far ultraviolet flux of a supergiant relative to a main sequence star is compared with the difference in the flux distribution due to a change of one spectral class. Individual interstellar reddening curves show the general feature reported by Stecher (1969) and by Bless and Savage (1970). There is a large amount of scatter in the far ultraviolet which may be partially due to a real difference in interstellar extinction and partially due to observational inaccuracy.
Fabrication of Compact Superconducting Lowpass Filters for Ultrasensitive Detectors
NASA Technical Reports Server (NTRS)
Brown, Ari; Chervenak, James; Chuss, David; Mikula, Vilem; Ray, Christopher; Rostem, Karwan; U-Yen, Kongpop; Wassell, Edward; Wollack, Edward
2012-01-01
It is extremely important for current and future far-infrared and sub-millimeter ultrasensitive detectors, which include transition edge sensors (TES) and microwave kinetic inductance detectors, to be adequately filtered from stray electromagnetic radiation in order to achieve their optimal performance. One means of filtering stray radiation is to block leakage associated with electrical connections in the detector environment. Here we discuss a fabrication methodology for realizing non-dissipative planar filters imbedded in the wall of the detector enclosure to limit wave propagation modes up to far-infrared frequencies. Our methodology consists of fabricating a boxed stripline transmission line, in which a superconducting (Nb, Mo, or Al) transmission line is encased in a silicon dioxide dielectric insulator coated with a metallic shell. We report on achieved attenuation and return loss and find that it replicates the simulated data to a high degree.
NASA Astrophysics Data System (ADS)
Gu, Zhou; Fei, Shumin; Yue, Dong; Tian, Engang
2014-07-01
This paper deals with the problem of H∞ filtering for discrete-time systems with stochastic missing measurements. A new missing measurement model is developed by decomposing the interval of the missing rate into several segments. The probability of the missing rate in each subsegment is governed by its corresponding random variables. We aim to design a linear full-order filter such that the estimation error converges to zero exponentially in the mean square with a less conservatism while the disturbance rejection attenuation is constrained to a given level by means of an H∞ performance index. Based on Lyapunov theory, the reliable filter parameters are characterised in terms of the feasibility of a set of linear matrix inequalities. Finally, a numerical example is provided to demonstrate the effectiveness and applicability of the proposed design approach.
High temperature charge amplifier for geothermal applications
Lindblom, Scott C.; Maldonado, Frank J.; Henfling, Joseph A.
2015-12-08
An amplifier circuit in a multi-chip module includes a charge to voltage converter circuit, a voltage amplifier a low pass filter and a voltage to current converter. The charge to voltage converter receives a signal representing an electrical charge and generates a voltage signal proportional to the input signal. The voltage amplifier receives the voltage signal from the charge to voltage converter, then amplifies the voltage signal by the gain factor to output an amplified voltage signal. The lowpass filter passes low frequency components of the amplified voltage signal and attenuates frequency components greater than a cutoff frequency. The voltage to current converter receives the output signal of the lowpass filter and converts the output signal to a current output signal; wherein an amplifier circuit output is selectable between the output signal of the lowpass filter and the current output signal.
Assessment of female breast dose for thoracic cone-beam CT using MOSFET dosimeters
Qiu, Bo; Liang, Jian; Xie, Weihao; Deng, Xiaowu; Qi, Zhenyu
2017-01-01
Objective: To assess the breast dose during a routine thoracic cone-beam CT (CBCT) check with the efforts to explore the possible dose reduction strategy. Materials and Methods: Metal oxide semiconductor field-effect transistor (MOSFET) dosimeters were used to measure breast surface doses during a thorax kV CBCT scan in an anthropomorphic phantom. Breast doses for different scanning protocols and breast sizes were compared. Dose reduction was attempted by using partial arc CBCT scan with bowtie filter. The impact of this dose reduction strategy on image registration accuracy was investigated. Results: The average breast surface doses were 20.02 mGy and 11.65 mGy for thoracic CBCT without filtration and with filtration, respectively. This indicates a dose reduction of 41.8% by use of bowtie filter. It was found 220° partial arc scanning significantly reduced the dose to contralateral breast (44.4% lower than ipsilateral breast), while the image registration accuracy was not compromised. Conclusions: Breast dose reduction can be achieved by using ipsilateral 220° partial arc scan with bowtie filter. This strategy also provides sufficient image quality for thorax image registration in daily patient positioning verification. PMID:28423624
MRI-guided brain PET image filtering and partial volume correction
NASA Astrophysics Data System (ADS)
Yan, Jianhua; Chu-Shern Lim, Jason; Townsend, David W.
2015-02-01
Positron emission tomography (PET) image quantification is a challenging problem due to limited spatial resolution of acquired data and the resulting partial volume effects (PVE), which depend on the size of the structure studied in relation to the spatial resolution and which may lead to over or underestimation of the true tissue tracer concentration. In addition, it is usually necessary to perform image smoothing either during image reconstruction or afterwards to achieve a reasonable signal-to-noise ratio. Typically, an isotropic Gaussian filtering (GF) is used for this purpose. However, the noise suppression is at the cost of deteriorating spatial resolution. As hybrid imaging devices such as PET/MRI have become available, the complementary information derived from high definition morphologic images could be used to improve the quality of PET images. In this study, first of all, we propose an MRI-guided PET filtering method by adapting a recently proposed local linear model and then incorporate PVE into the model to get a new partial volume correction (PVC) method without parcellation of MRI. In addition, both the new filtering and PVC are voxel-wise non-iterative methods. The performance of the proposed methods were investigated with simulated dynamic FDG brain dataset and 18F-FDG brain data of a cervical cancer patient acquired with a simultaneous hybrid PET/MR scanner. The initial simulation results demonstrated that MRI-guided PET image filtering can produce less noisy images than traditional GF and bias and coefficient of variation can be further reduced by MRI-guided PET PVC. Moreover, structures can be much better delineated in MRI-guided PET PVC for real brain data.
Simplified procedure for computing the absorption of sound by the atmosphere
DOT National Transportation Integrated Search
2007-10-31
This paper describes a study that resulted in the development of a simplified : method for calculating attenuation by atmospheric-absorption for wide-band : sounds analyzed by one-third octave-band filters. The new method [referred to : herein as the...
Entropy-guided switching trimmed mean deviation-boosted anisotropic diffusion filter
NASA Astrophysics Data System (ADS)
Nnolim, Uche A.
2016-07-01
An effective anisotropic diffusion (AD) mean filter variant is proposed for filtering of salt-and-pepper impulse noise. The implemented filter is robust to impulse noise ranging from low to high density levels. The algorithm involves a switching scheme in addition to utilizing the unsymmetric trimmed mean/median deviation to filter image noise while greatly preserving image edges, regardless of impulse noise density (ND). It operates with threshold parameters selected manually or adaptively estimated from the image statistics. It is further combined with the partial differential equations (PDE)-based AD for edge preservation at high NDs to enhance the properties of the trimmed mean filter. Based on experimental results, the proposed filter easily and consistently outperforms the median filter and its other variants ranging from simple to complex filter structures, especially the known PDE-based variants. In addition, the switching scheme and threshold calculation enables the filter to avoid smoothing an uncorrupted image, and filtering is activated only when impulse noise is present. Ultimately, the particular properties of the filter make its combination with the AD algorithm a unique and powerful edge-preservation smoothing filter at high-impulse NDs.
Compact silicon photonic resonance-assisted variable optical attenuator
Wang, Xiaoxi; Aguinaldo, Ryan; Lentine, Anthony; ...
2016-11-17
Here, a two-part silicon photonic variable optical attenuator is demonstrated in a compact footprint which can provide a high extinction ratio at wavelengths between 1520 nm and 1620 nm. The device was made by following the conventional p-i-n waveguide section by a high-extinction-ratio second-order microring filter section. The rings provide additional on-off contrast by utilizing a thermal resonance shift, which harvested the heat dissipated by current injection in the p-i-n junction. Finally, we derive and discuss a simple thermal-resistance model in explanation of these effects.
Compact silicon photonic resonance-sssisted variable optical attenuator.
Wang, Xiaoxi; Aguinaldo, Ryan; Lentine, Anthony; DeRose, Christopher; Starbuck, Andrew L; Trotter, Douglas; Pomerene, Andrew; Mookherjea, Shayan
2016-11-28
A two-part silicon photonic variable optical attenuator is demonstrated in a compact footprint which can provide a high extinction ratio at wavelengths between 1520 nm and 1620 nm. The device was made by following the conventional p-i-n waveguide section by a high-extinction-ratio second-order microring filter section. The rings provide additional on-off contrast by utilizing a thermal resonance shift, which harvested the heat dissipated by current injection in the p-i-n junction. We derive and discuss a simple thermal-resistance model in explanation of these effects.
Transfer function concept for ultrasonic characterization of material microstructures
NASA Technical Reports Server (NTRS)
Vary, A.; Kautz, H. E.
1986-01-01
The approach given depends on treating material microstructures as elastomechanical filters that have analytically definable transfer functions. These transfer functions can be defined in terms of the frequency dependence of the ultrasonic attenuation coefficient. The transfer function concept provides a basis for synthesizing expressions that characterize polycrystalline materials relative to microstructural factors such as mean grain size, grain-size distribution functions, and grain boundary energy transmission. Although the approach is nonrigorous, it leads to a rational basis for combining the previously mentioned diverse and fragmented equations for ultrasonic attenuation coefficients.
Comparative studies on the retardation and reduction of glyphosate during subsurface passage.
Litz, N T; Weigert, A; Krause, B; Heise, S; Grützmacher, G
2011-05-01
The herbicide Glyphosate was detected in River Havel (Berlin, Germany) in concentrations between 0.1 and 2 μg/L (single maximum outlier: 5 μg/L). As the river indirectly acts as drinking water source for the city's 3.4 Mio inhabitants potential risks for drinking water production needed to be assessed. For this reason laboratory (sorption and degradation studies) and technical scale investigations (bank filtration and slow sand filter experiments) were carried out. Batch adsorption experiments with Glyphosate yielded a low K(F) of 1.89 (1/n = 0.48) for concentrations between 0.1 and 100 mg/L. Degradation experiments at 8 °C with oxygen limitation resulted in a decrease of Glyphosate concentrations in the liquid phase probably due to slow adsorption (half life: 30 days). During technical scale slow sand filter (SSF) experiments Glyphosate attenuation was 70-80% for constant inlet concentrations of 0.7, 3.5 and 11.6 μg/L, respectively. Relevant retardation of Glyphosate breakthrough was observed despite the low adsorption potential of the sandy filter substrate and the relatively high flow velocity. The VisualCXTFit model was applied with data from typical Berlin bank filtration sites to extrapolate the results to a realistic field setting and yielded sufficient attenuation within a few days of travel time. Experiments on an SSF planted with Phragmites australis and an unplanted SSF with mainly vertical flow conditions to which Glyphosate was continuously dosed showed that in the planted SSF Glyphosate retardation exceeds 54% compared to 14% retardation in the unplanted SSF. The results show that saturated subsurface passage has the potential to efficiently attenuate glyphosate, favorably with aerobic conditions, long travel times and the presence of planted riparian boundary buffer strips. Copyright © 2011 Elsevier Ltd. All rights reserved.
Time-frequency peak filtering for random noise attenuation of magnetic resonance sounding signal
NASA Astrophysics Data System (ADS)
Lin, Tingting; Zhang, Yang; Yi, Xiaofeng; Fan, Tiehu; Wan, Ling
2018-05-01
When measuring in a geomagnetic field, the method of magnetic resonance sounding (MRS) is often limited because of the notably low signal-to-noise ratio (SNR). Most current studies focus on discarding spiky noise and power-line harmonic noise cancellation. However, the effects of random noise should not be underestimated. The common method for random noise attenuation is stacking, but collecting multiple recordings merely to suppress random noise is time-consuming. Moreover, stacking is insufficient to suppress high-level random noise. Here, we propose the use of time-frequency peak filtering for random noise attenuation, which is performed after the traditional de-spiking and power-line harmonic removal method. By encoding the noisy signal with frequency modulation and estimating the instantaneous frequency using the peak of the time-frequency representation of the encoded signal, the desired MRS signal can be acquired from only one stack. The performance of the proposed method is tested on synthetic envelope signals and field data from different surveys. Good estimations of the signal parameters are obtained at different SNRs. Moreover, an attempt to use the proposed method to handle a single recording provides better results compared to 16 stacks. Our results suggest that the number of stacks can be appropriately reduced to shorten the measurement time and improve the measurement efficiency.
Brockmann, D; Morgenroth, E
2010-03-01
In practice, partial nitrification to nitrite in biofilms has been achieved with a range of different operating conditions, but mechanisms resulting in reliable partial nitrification in biofilms are not well understood. In this study, mathematical biofilm modeling combined with Monte Carlo filtering was used to evaluate operating conditions that (1) lead to outcompetition of nitrite oxidizers from the biofilm, and (2) allow to maintain partial nitrification during long-term operation. Competition for oxygen was found to be the main mechanism for displacing nitrite oxidizers from the biofilm, and preventing re-growth of nitrite oxidizers in the long-term. To maintain partial nitrification in the model, a larger oxygen affinity (i.e., smaller half saturation constant) for ammonium oxidizers compared to nitrite oxidizers was required, while the difference in maximum growth rate was not important for competition under steady state conditions. Thus, mechanisms for washout of nitrite oxidizing bacteria from biofilms are different from suspended cultures where the difference in maximum growth rate is a key mechanism. Inhibition of nitrite oxidizers by free ammonia was not required to outcompete nitrite oxidizers from the biofilm, and to maintain partial nitrification to nitrite. But inhibition by free ammonia resulted in faster washout of nitrite oxidizers. Copyright 2009 Elsevier Ltd. All rights reserved.
Liu, Peilu; Li, Xinghua; Li, Haopeng; Su, Zhikun; Zhang, Hongxu
2017-10-12
In order to improve the accuracy of ultrasonic phased array focusing time delay, analyzing the original interpolation Cascade-Integrator-Comb (CIC) filter, an 8× interpolation CIC filter parallel algorithm was proposed, so that interpolation and multichannel decomposition can simultaneously process. Moreover, we summarized the general formula of arbitrary multiple interpolation CIC filter parallel algorithm and established an ultrasonic phased array focusing time delay system based on 8× interpolation CIC filter parallel algorithm. Improving the algorithmic structure, 12.5% of addition and 29.2% of multiplication was reduced, meanwhile the speed of computation is still very fast. Considering the existing problems of the CIC filter, we compensated the CIC filter; the compensated CIC filter's pass band is flatter, the transition band becomes steep, and the stop band attenuation increases. Finally, we verified the feasibility of this algorithm on Field Programming Gate Array (FPGA). In the case of system clock is 125 MHz, after 8× interpolation filtering and decomposition, time delay accuracy of the defect echo becomes 1 ns. Simulation and experimental results both show that the algorithm we proposed has strong feasibility. Because of the fast calculation, small computational amount and high resolution, this algorithm is especially suitable for applications with high time delay accuracy and fast detection.
Brain pertechnetate SPECT in perinatal asphyxia
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sfakianakis, G.; Curless, R.; Goldberg, R.
1984-01-01
Single photon emission computed tomography of the brain was performed in 6 patients with perinatal asphyxis aged 8-26 days. A single-head (LFOV) commercial SPECT system (Picker) was used and data were acquired 2-3 hr after an IV injection of 1-2 mCi Tc-99m-pertechnetate (360/sup 0/ rotation, 60 views, 64 x 64 matrix, 50K cts/view). Reconstruction in three planes was performed using MDS software (Hanning medium resolution filter, with or without attenuation correction using Sorenson's technique). For each clinical study, a ring type phantom source was used to identify the level of reconstruction noise in the tomographic planes. Abnormalities were found inmore » all patients studied, 3 central (moderate intensity), 2 peripheral (1 severe, 1 moderate) and 1 diffuse (mild intensity). Despite use of oral perchlorate (50 mg) in one patient the choroid plexus was visible. Since attenuation correction tended to amplify noise, the clinical studies were interpreted both with and without this correction. All 3 patients with central lesions were found abnormal on early (1-4 mo) neurologic follow-up examination, whereas the others were normal. No correlation was found between SPECT and 24 hr blood levels of CPK, ammonia, base excess, or the Apgar scores. Ct scans were reported abnormal (3 diffuse, 1 peripheral, 1 central and 1 questionable). Planar scintigrams obtained immediately after SPECT were normal (2), questionable (2) and abnormal (2). Follow-up SPECT brain scintigrams in two of the patients showed partial resolution. SPECT of the brain appears promising in perinatal asphyxia but long-term correlation with patient development is necessary.« less
Rodriguez Lanzi, Cecilia; de Rosas, Inés; Perdicaro, Diahann J; Ponce, María Teresa; Martinez, Liliana; Miatello, Roberto M; Cavagnaro, Bruno; Vazquez Prieto, Marcela A
2016-12-01
We evaluated the effects of Syrah red wine treated with salicylic acid (RW SA) and its control red wine (RW) on metabolic parameters, systolic blood pressure and adipose tissue insulin signaling in high-fructose (F) fed rats. Grape treated with SA increased the anthocyanin (ANTs) levels in RW. F induced increased systolic blood pressure, dislipidemia and insulin resistance (HOMA:IR). F rats treated with RW significantly prevented these alterations while RW SA partially attenuated triglycerides levels and HOMA:IR without modifications in HDL cholesterol levels. F impaired the adipose tissue response to insulin. Supplementation with RW and RW SA partially attenuated these alterations. Rats supplemented with RW SA had lesser beneficial effects on metabolic alterations than control RW, while both RW and RW SA attenuated altered adipose response to insulin. More studies are necessary to deeply evaluate the effect on SA-induced RW rich in ANTs levels on metabolic alterations associated to MetS.
Restricted diffusion in a model acinar labyrinth by NMR: Theoretical and numerical results
NASA Astrophysics Data System (ADS)
Grebenkov, D. S.; Guillot, G.; Sapoval, B.
2007-01-01
A branched geometrical structure of the mammal lungs is known to be crucial for rapid access of oxygen to blood. But an important pulmonary disease like emphysema results in partial destruction of the alveolar tissue and enlargement of the distal airspaces, which may reduce the total oxygen transfer. This effect has been intensively studied during the last decade by MRI of hyperpolarized gases like helium-3. The relation between geometry and signal attenuation remained obscure due to a lack of realistic geometrical model of the acinar morphology. In this paper, we use Monte Carlo simulations of restricted diffusion in a realistic model acinus to compute the signal attenuation in a diffusion-weighted NMR experiment. We demonstrate that this technique should be sensitive to destruction of the branched structure: partial removal of the interalveolar tissue creates loops in the tree-like acinar architecture that enhance diffusive motion and the consequent signal attenuation. The role of the local geometry and related practical applications are discussed.
Feldkaemper, M; Diether, S; Kleine, G; Schaeffel, F
1999-01-01
Degrading the retinal image by frosted eye occluders produces elongated eyes and 'deprivation myopia' in a variety of animal models. The postulated retinal 'deprivation detector' is quite sensitive to even small changes in image contrast or spatial frequency composition. Because psychophysical experiments have shown that a decline in luminance shifts the contrast sensitivity function to lower spatial frequencies, it is likely that only a reduced spatial frequency range is available for image analysis to control eye growth. It is even possible that the compression might be sufficient to promote deprivation myopia. We have tested this hypothesis, using the animal model of the chicken. (1) At an ambient illumination of 550 lux (about 76 cd m-2), neutral density (ND) filters placed in front of the eye with 0.0, 0.5 or 1.0 log unit attenuation did not change refractive development. However, monocularly or binocularly attached filters with 2 log units attenuation produced 5-7 D of myopia relative to normal eyes. Black occluders were not more effective. Frosted eye occluders with little effect on image brightness (about 0.5 log units attenuation) produced much more myopia (about 16 D compared with the controls). (2) The effects of the ND filters on refractive development could not be reproduced if the ambient illumination was reduced by 2 log units. Probably, minor effects on image quality were introduced by optical imperfections of the ND filters which were more critical at low retinal image brightness. (3) In an optomotor experiment (spatial frequency 0.2 cyc deg-1, stripe speed 57 deg sec-1), it was shown that the chickens' contrast sensitivity was severely reduced when the eyes were covered by 2.0 ND filters. (4) Since there is evidence that changes in dopamine release from the retina may be one of the factors affecting the development of myopia, we have tested how selective these changes were for spatial information. It was found that dopamine release was controlled by both spatial and luminance information and that the inputs of both could be scarcely separated. (5) Because the experiments show that the eye becomes more sensitive to image degradation at low light, the human eye may also be more prone to develop myopia if the light levels are low during extended periods of near work. Copyright 1999 Academic Press.
Image reconstruction of x-ray tomography by using image J platform
NASA Astrophysics Data System (ADS)
Zain, R. M.; Razali, A. M.; Salleh, K. A. M.; Yahya, R.
2017-01-01
A tomogram is a technical term for a CT image. It is also called a slice because it corresponds to what the object being scanned would look like if it were sliced open along a plane. A CT slice corresponds to a certain thickness of the object being scanned. So, while a typical digital image is composed of pixels, a CT slice image is composed of voxels (volume elements). In the case of x-ray tomography, similar to x-ray Radiography, the quantity being imaged is the distribution of the attenuation coefficient μ(x) within the object of interest. The different is only on the technique to produce the tomogram. The image of x-ray radiography can be produced straight foward after exposed to x-ray, while the image of tomography produces by combination of radiography images in every angle of projection. A number of image reconstruction methods by converting x-ray attenuation data into a tomography image have been produced by researchers. In this work, Ramp filter in "filtered back projection" has been applied. The linear data acquired at each angular orientation are convolved with a specially designed filter and then back projected across a pixel field at the same angle. This paper describe the step of using Image J software to produce image reconstruction of x-ray tomography.
Experimental entanglement distillation and 'hidden' non-locality.
Kwiat, P G; Barraza-Lopez, S; Stefanov, A; Gisin, N
2001-02-22
Entangled states are central to quantum information processing, including quantum teleportation, efficient quantum computation and quantum cryptography. In general, these applications work best with pure, maximally entangled quantum states. However, owing to dissipation and decoherence, practically available states are likely to be non-maximally entangled, partially mixed (that is, not pure), or both. To counter this problem, various schemes of entanglement distillation, state purification and concentration have been proposed. Here we demonstrate experimentally the distillation of maximally entangled states from non-maximally entangled inputs. Using partial polarizers, we perform a filtering process to maximize the entanglement of pure polarization-entangled photon pairs generated by spontaneous parametric down-conversion. We have also applied our methods to initial states that are partially mixed. After filtering, the distilled states demonstrate certain non-local correlations, as evidenced by their violation of a form of Bell's inequality. Because the initial states do not have this property, they can be said to possess 'hidden' non-locality.
Bessel smoothing filter for spectral-element mesh
NASA Astrophysics Data System (ADS)
Trinh, P. T.; Brossier, R.; Métivier, L.; Virieux, J.; Wellington, P.
2017-06-01
Smoothing filters are extremely important tools in seismic imaging and inversion, such as for traveltime tomography, migration and waveform inversion. For efficiency, and as they can be used a number of times during inversion, it is important that these filters can easily incorporate prior information on the geological structure of the investigated medium, through variable coherent lengths and orientation. In this study, we promote the use of the Bessel filter to achieve these purposes. Instead of considering the direct application of the filter, we demonstrate that we can rely on the equation associated with its inverse filter, which amounts to the solution of an elliptic partial differential equation. This enhances the efficiency of the filter application, and also its flexibility. We apply this strategy within a spectral-element-based elastic full waveform inversion framework. Taking advantage of this formulation, we apply the Bessel filter by solving the associated partial differential equation directly on the spectral-element mesh through the standard weak formulation. This avoids cumbersome projection operators between the spectral-element mesh and a regular Cartesian grid, or expensive explicit windowed convolution on the finite-element mesh, which is often used for applying smoothing operators. The associated linear system is solved efficiently through a parallel conjugate gradient algorithm, in which the matrix vector product is factorized and highly optimized with vectorized computation. Significant scaling behaviour is obtained when comparing this strategy with the explicit convolution method. The theoretical numerical complexity of this approach increases linearly with the coherent length, whereas a sublinear relationship is observed practically. Numerical illustrations are provided here for schematic examples, and for a more realistic elastic full waveform inversion gradient smoothing on the SEAM II benchmark model. These examples illustrate well the efficiency and flexibility of the approach proposed.
Capmany, José; Mora, José; Ortega, Beatriz; Pastor, Daniel
2005-03-07
We propose and experimentally demonstrate two configurations of photonic filters for the processing of microwave signals featuring tunability, reconfigurability and negative coefficients based on the use of low cost optical sources. The first option is a low power configuration based on spectral slicing of a broadband source. The second is a high power configuration based on fixed lasers. Tunability, reconfigurability and negative coefficients are achieved by means of a MEMS cross-connect, a variable optical attenuator array and simple 2x2 switches respectively.
NASA Astrophysics Data System (ADS)
Kwak, J. S.; Lee, J. H.; Kim, C. O.; Hong, J. P.; Han, S. K.; Char, K.
2002-07-01
Highly selective high-temperature superconducting band-pass filters based on spiral meander line structures have been developed for base transceiver station applications of digital cellular communication systems. The filter comprised 12-pole microstrip line resonators with a circuit size of 0.5 × 17 × 41 mm3. The filter was designed to have a bandwidth of 25 MHz at a centre frequency of 834 MHz. Particularly, the physical size of each resonator was chosen not only to reduce far-field radiation, but also to have reasonable tunability in the filter. Device characteristics exhibited a low insertion loss of 0.4 dB with a 0.2 dB ripple and a return loss better than 10 dB in the pass-band at 65 K. The out-of-band signals were attenuated better than 60 dB at about 3.5 MHz from the lower band edge, and 3.8 MHz from the higher band edge.
Equalizing secondary path effects using the periodicity of fMRI acoustic noise.
Kannan, Govind; Milani, Ali A; Panahi, Issa; Briggs, Richard
2008-01-01
Non-minimum phase secondary path has a direct effect on achieving a desired noise attenuation level in active noise control (ANC) systems. The adaptive noise canceling filter is often a causal FIR filter which may not be able to sufficiently equalize the effect of a non-minimum phase secondary path, since in theory only a non-causal filter can equalize it. However a non-causal stable filter can be found to equalize the non-minimum phase effect of secondary path. Realization of non-causal stable filters requires knowledge of future values of input signal. In this paper we develop methods for equalizing the non-minimum phase property of the secondary path and improving the performance of an ANC system by exploiting the periodicity of fMRI acoustic noise. It has been shown that the scanner noise component is highly periodic and hence predictable which enables easy realization of non-causal filtering. Improvement in performance due to the proposed methods (with and without the equalizer) is shown for periodic fMRI acoustic noise.
Successive Negative Contrast after Partial Reinforcement in the Consummatory Behavior of Rats
ERIC Educational Resources Information Center
Pellegrini, Santiago; Muzio, Ruben N.; Mustaca, Alba E.; Papini, Mauricio R.
2004-01-01
Rats given access to a 32% sucrose solution later reject a 4% solution significantly more than controls that have only received the 4% solution. In Experiment 1, this consummatory successive negative contrast (cSNC) effect was attenuated by previous exposure to 50% partial reinforcement. Furthermore, recovery from cSNC was also facilitated by…
Fluence-field modulated x-ray CT using multiple aperture devices
NASA Astrophysics Data System (ADS)
Stayman, J. Webster; Mathews, Aswin; Zbijewski, Wojciech; Gang, Grace; Siewerdsen, Jeffrey; Kawamoto, Satomi; Blevis, Ira; Levinson, Reuven
2016-03-01
We introduce a novel strategy for fluence field modulation (FFM) in x-ray CT using multiple aperture devices (MADs). MAD filters permit FFM by blocking or transmitting the x-ray beam on a fine (0.1-1 mm) scale. The filters have a number of potential advantages over other beam modulation strategies including the potential for a highly compact design, modest actuation speed and acceleration requirements, and spectrally neutral filtration due to their essentially binary action. In this work, we present the underlying MAD filtration concept including a design process to achieve a specific class of FFM patterns. A set of MAD filters is fabricated using a tungsten laser sintering process and integrated into an x-ray CT test bench. A characterization of the MAD filters is conducted and compared to traditional attenuating bowtie filters and the ability to flatten the fluence profile for a 32 cm acrylic phantom is demonstrated. MAD-filtered tomographic data was acquired on the CT test bench and reconstructed without artifacts associated with the MAD filter. These initial studies suggest that MAD-based FFM is appropriate for integration in clinical CT system to create patient-specific fluence field profile and reduce radiation exposures.
Development of an adaptive bilateral filter for evaluating color image difference
NASA Astrophysics Data System (ADS)
Wang, Zhaohui; Hardeberg, Jon Yngve
2012-04-01
Spatial filtering, which aims to mimic the contrast sensitivity function (CSF) of the human visual system (HVS), has previously been combined with color difference formulae for measuring color image reproduction errors. These spatial filters attenuate imperceptible information in images, unfortunately including high frequency edges, which are believed to be crucial in the process of scene analysis by the HVS. The adaptive bilateral filter represents a novel approach, which avoids the undesirable loss of edge information introduced by CSF-based filtering. The bilateral filter employs two Gaussian smoothing filters in different domains, i.e., spatial domain and intensity domain. We propose a method to decide the parameters, which are designed to be adaptive to the corresponding viewing conditions, and the quantity and homogeneity of information contained in an image. Experiments and discussions are given to support the proposal. A series of perceptual experiments were conducted to evaluate the performance of our approach. The experimental sample images were reproduced with variations in six image attributes: lightness, chroma, hue, compression, noise, and sharpness/blurriness. The Pearson's correlation values between the model-predicted image difference and the observed difference were employed to evaluate the performance, and compare it with that of spatial CIELAB and image appearance model.
NASA Astrophysics Data System (ADS)
Samiksha, S.; Raman, R. S.; Singh, A.
2016-12-01
It is now well recognized that black carbon (a component of aerosols that is similar but not identical to elemental carbon) is an important contributor to global warming, second only to CO2.However, the most popular methods for estimation of black carbon rely on accurate estimates of its mass absorption efficiency (MAE) to convert optical attenuation measurements to black carbon concentrations. Often a constant manufacturer specified MAE is used for this purposes. Recent literature has unequivocally established that MAE shows large spatio-temporal heterogeneities. This is so because MAE depends on emission sources, chemical composition, and mixing state of aerosols. In this study, ambient PM2.5 samples were collected over an ecologically sensitive zone (Van Vihar National Park) in Bhopal, Central India for two years (01 January, 2012 to 31 December, 2013). Samples were collected on Teflon, Nylon, and Tissue quartz filter substrates. Punches of quartz fibre filter were analysed for organic and elemental carbon (OC/EC) by a thermal-optical-transmittance/reflectance (TOT-TOR) analyser operating with a 632 nm laser diode. Teflon filters were also used to interdependently measure PM2.5 attenuation (at 370 nm and 800 nm) by transmissometry. Site-specific mass absorption efficiency (MAE) for elemental carbon over the study site will be derived using a combination of measurements from the TOT/TOR analyser and transmissometer. An assessment of site-specific MAE values, its temporal variability and implications to black carbon radiative forcing will be discussed. It is now well recognized that black carbon (a component of aerosols that is similar but not identical to elemental carbon) is an important contributor to global warming, second only to CO2. However, the most popular methods for estimation of black carbon rely on accurate estimates of its mass absorption efficiency (MAE) to convert optical attenuation measurements to black carbon concentrations. Often a constant manufacturer specified MAE is used for this purposes. Recent literature has unequivocally established that MAE shows large spatio-temporal heterogeneities. This is so because MAE depends on emission sources, chemical composition, and mixing state of aerosols. In this study, ambient PM2.5 samples were collected over an ecologically sensitive zone (Van Vihar National Park) in Bhopal, Central India for two years (01 January, 2012 to 31 December, 2013). Samples were collected on Teflon, Nylon, and Tissue quartz filter substrates. Punches of quartz fibre filter were analysed for organic and elemental carbon (OC/EC) by a thermal-optical-transmittance/reflectance (TOT-TOR) analyser operating with a 632 nm laser diode. Teflon filters were also used to interdependently measure PM2.5 attenuation (at 370 nm and 800 nm) by transmissometry. Site-specific mass absorption efficiency (MAE) for elemental carbon over the study site will be derived using a combination of measurements from the TOT/TOR analyser and transmissometer. An assessment of site-specific MAE values, its temporal variability and implications to black carbon radiative forcing will be discussed.
Inverter Output Filter Effect on PWM Motor Drives of a Flywheel Energy Storage System
NASA Technical Reports Server (NTRS)
Santiago, Walter
2004-01-01
NASA Glenn Research Center (GRC) has been involved in the research and development of high speed flywheel systems for small satellite energy storage and attitude control applications. One research and development area has been the minimization of the switching noise produced by the pulsed width modulated (PWM) inverter that drives the flywheel permanent magnet motor/generator (PM M/G). This noise can interfere with the flywheel M/G hardware and the system avionics hampering the full speed performance of the flywheel system. One way to attenuate the inverter switching noise is by placing an AC filter at the three phase output terminals of the inverter with the filter neutral point connected to the DC link (DC bus) midpoint capacitors. The main benefit of using an AC filter in this fashion is the significant reduction of the inverter s high dv/dt switching and its harmonics components. Additionally, common mode (CM) and differential mode (DM) voltages caused by the inverter s high dv/dt switching are also reduced. Several topologies of AC filters have been implemented and compared. One AC filter topology consists of a two-stage R-L-C low pass filter. The other topology consists of the same two-stage R-L-C low pass filter with a series connected trap filter (an inductor and capacitor connected in parallel). This paper presents the analysis, design and experimental results of these AC filter topologies and the comparison between the no filter case and conventional AC filter.
Damping system for torsion modes of mirror isolation filters in TAMA300
NASA Astrophysics Data System (ADS)
Arase, Y.; Takahashi, R.; Arai, K.; Tatsumi, D.; Fukushima, M.; Yamazaki, T.; Fujimoto, Masa-Katsu; Agatsuma, K.; Nakagawa, N.
2008-07-01
The seismic attenuation system (SAS) in TAMA300 consists of a three-legged inverted pendulum and mirror isolation filters in order to provide a high level of seismic isolation. However, the mirror isolation filters have torsion modes with long decay time which disturb the interferometer operation for about half an hour if they get excited. In order to damp the torsion modes of the filters, we constructed a digital damping system using reflective photosensors with a large linear range. This system was installed to all of four SASs. By damping of the target torsion modes, the effective quality factors of the torsion modes are reduced to less than 10 or to unmeasurable level. This system is expected to reduce the inoperative period by the torsion mode excitation, and thus will contribute to improve the duty time of the gravitational wave detector.
Miremad, Seyed Milad; Shirani, Babak
2018-06-01
In this paper, effective energy of pulsed X-Ray emitted from a Mather-type plasma focus device in stored energy of 2.5 kJ with six different anode's insert materials was measured using radiographic method with attenuation filters. Since intensity and energy of X-ray beam were considerably changed with changing the insert material, the method was improved by using different filters simultaneously in all the experiments and selection of the best filter in each experiment according to the appropriate criteria. Effective energy of pulsed X-ray beam was measured 16, 28, 50, 51, 34 and 44 keV when aluminum, copper, zinc, tin, tungsten and lead were used as insert materials, and aluminum, copper, silver, silver, copper and lead were used as filters, respectively. Copyright © 2018 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Kumari, Puja; Mudiganti, Jagadish Chandra
2017-11-01
In this work bandpass filter based on SIW technology with an adequate fractional bandwidth as well as refinement in the stopband performance is presented. Its application lies with the receiver filter working in the Ka band used mainly in the ground terminal for satellite communication. Additionally analysis of divergent input/output arrangement is also demonstrated. Three SIW filter having a varying passband from 19.2GHz -21.2GHz depending on the input/output are synthesized on a planar substrate having height of 0.508mm RT/duroid 6002 using periodically arranged metal via holes through a regulated PCB process. Simulated outputs has a in-band insertion loss 0.9dB and the improved stopband attenuation within the frequency range of 29.5GHz - 31GHz is around 45 dB. It is observed that the experimented results coincide completely with the results simulated in HFSS/CST.
A bandpass filter for the enhancement of an X-ray reconstruction of the tissue in the spinal canal
NASA Technical Reports Server (NTRS)
Reed, I. S.; Glenn, W. V.; Kwoh, Y. S.; Truong, T. K.
1980-01-01
In this communication, a new bandpass reconstruction filter is developed to partially remove the low spatial frequencies of the bone and the soft tissue in an X-ray reconstruction of a lumbar spine. This partial removal of the low frequencies suppresses the bony vertebral body and the soft tissue components within the projections of actual clinical data. It also has the effect of enhancing the sharp edges of the fatty tissue surrounding the spinal cord region. The intent of this effort is to directly visualize the spinal cord without the need for water-soluble contrast (e.g., metrizamide) to be installed through lumbar punctures.
Tang, Chen; Han, Lin; Ren, Hongwei; Zhou, Dongjian; Chang, Yiming; Wang, Xiaohang; Cui, Xiaolong
2008-10-01
We derive the second-order oriented partial-differential equations (PDEs) for denoising in electronic-speckle-pattern interferometry fringe patterns from two points of view. The first is based on variational methods, and the second is based on controlling diffusion direction. Our oriented PDE models make the diffusion along only the fringe orientation. The main advantage of our filtering method, based on oriented PDE models, is that it is very easy to implement compared with the published filtering methods along the fringe orientation. We demonstrate the performance of our oriented PDE models via application to two computer-simulated and experimentally obtained speckle fringes and compare with related PDE models.
NASA Astrophysics Data System (ADS)
Chen, Yangyang; Huang, Guoliang
2017-04-01
A great deal of research has been devoted to controlling the dynamic behaviors of phononic crystals and metamaterials by directly tuning the frequency regions and/or widths of their inherent band gaps. Here, we present a novel approach to achieve extremely broadband flexural wave/vibration attenuation based on tunable local resonators made of piezoelectric stacks shunted by hybrid negative capacitance and negative inductance circuits with proof masses attached on a host beam. First, wave dispersion relations of the adaptive metamaterial beam are calculated analytically by using the transfer matrix method. The unique modulus tuning properties induced by the hybrid shunting circuits are then characterized conceptually, from which the frequency dependent modulus tuning curves of the piezoelectric stack located within wave attenuation frequency regions are quantitatively identified. As an example, a flexural wave high-pass band filter with a wave attenuation region from 0 to 23.0 kHz is demonstrated analytically and numerically by using the hybrid shunting circuit, in which the two electric components are connected in series. By changing the connection pattern to be parallel, another super wide wave attenuation region from 13.5 to 73.0 kHz is demonstrated to function as a low-pass filter at a subwavelength scale. The proposed adaptive metamaterial possesses a super wide band gap created both naturally and artificially. Therefore, it can be used for the transient wave mitigation at extremely broadband frequencies such as blast or impact loadings. We envision that the proposed design and approach can open many possibilities in broadband vibration and wave control.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, Xinhua; Shi, Jim Q.; Zhang, Da
Purpose: To present a noninvasive technique for directly measuring the CT bow-tie filter attenuation with a linear array x-ray detector. Methods: A scintillator based x-ray detector of 384 pixels, 307 mm active length, and fast data acquisition (model X-Scan 0.8c4-307, Detection Technology, FI-91100 Ii, Finland) was used to simultaneously detect radiation levels across a scan field-of-view. The sampling time was as short as 0.24 ms. To measure the body bow-tie attenuation on a GE Lightspeed Pro 16 CT scanner, the x-ray tube was parked at the 12 o’clock position, and the detector was centered in the scan field at themore » isocenter height. Two radiation exposures were made with and without the bow-tie in the beam path. Each readout signal was corrected for the detector background offset and signal-level related nonlinear gain, and the ratio of the two exposures gave the bow-tie attenuation. The results were used in the GEANT4 based simulations of the point doses measured using six thimble chambers placed in a human cadaver with abdomen/pelvis CT scans at 100 or 120 kV, helical pitch at 1.375, constant or variable tube current, and distinct x-ray tube starting angles. Results: Absolute attenuation was measured with the body bow-tie scanned at 80–140 kV. For 24 doses measured in six organs of the cadaver, the median or maximum difference between the simulation results and the measurements on the CT scanner was 8.9% or 25.9%, respectively. Conclusions: The described method allows fast and accurate bow-tie filter characterization.« less
Light Modulates Ocular Complications in an Albino Rat Model of Type 1 Diabetes Mellitus.
Andrawus, Elias; Veildbaum, Gizi; Zemel, Esther; Leibu, Rina; Perlman, Ido; Shehadeh, Naim
2017-07-01
The purpose of the study was to assess potential interactions of light exposure and hyperglycemia upon ocular complications in diabetic rats. Streptozotocin-induced (STZ-induced) diabetic rats ( N = 39) and non-diabetic rats ( N = 9) were distributed into eight groups according to the irradiance and color of the light phase during the 12/12-hour light/dark regime. Follow-up lasted 90 days and included assessment of cataract development and electroretinogram (ERG) recordings. Stress to the retina was also assessed by glial fibrillary acidic protein immunocytochemistry. Cataract development was fast in diabetic rats that were exposed to unattenuated white light or to bright colored lights during the light phase. Diabetic rats that were kept under attenuated brown or yellow light during the light phase exhibited slower rate of cataract development. Electroretinogram responses indicated very severe retinal damage in diabetic rats kept under bright colored lights in the blue-yellow range or bright white light during the light phase. Electroretinogram damage was milder in rats kept under bright red light or attenuated yellow or brown light during the light phase. Glial fibrillary acidic protein expression in retinal Müller cells was consistent with ERG assessment of retinal damage. Attenuating white light and filtering out short wavelengths have a protective effect on the eyes of diabetic rats as evident by slower rate of cataract formation and a smaller degree of retinal damage. Our findings suggest that special glasses attenuating light exposure and filtering out short wavelengths (400-530 nm) may be beneficial for diabetic patients.
Assimilation of attenuated data from X-band network radars using ensemble Kalman filter
NASA Astrophysics Data System (ADS)
Cheng, Jing
To use reflectivity data from X-band radars for quantitative precipitation estimation and storm-scale data assimilation, the effect of attenuation must be properly accounted for. Traditional approaches try to make correction to the attenuated reflectivity first before using the data. An alternative, theoretically more attractive approach builds the attenuation effect into the reflectivity observation operator of a data assimilation system, such as an ensemble Kalman filter (EnKF), allowing direct assimilation of the attenuated reflectivity and taking advantage of microphysical state estimation using EnKF methods for a potentially more accurate solution. This study first tests the approach for the CASA (Center for Collaborative Adaptive Sensing of the Atmosphere) X-band radar network configuration through observing system simulation experiments (OSSE) for a quasi-linear convective system (QLCS) that has more significant attenuation than isolated storms. To avoid the problem of potentially giving too much weight to fully attenuated reflectivity, an analytical, echo-intensity-dependent model for the observation error (AEM) is developed and is found to improve the performance of the filter. By building the attenuation into the forward observation operator and combining it with the application of AEM, the assimilation of attenuated CASA observations is able to produce a reasonably accurate analysis of the QLCS inside CASA radar network coverage. Compared with foregoing assimilation of radar data with weak radar reflectivity or assimilating only radial velocity data, our method can suppress the growth of spurious echoes while obtaining a more accurate analysis in the terms of root-mean-square (RMS) error. Sensitivity experiments are designed to examine the effectiveness of AEM by introducing multiple sources of observation errors into the simulated observations. The performance of such an approach in the presence of resolution-induced model error is also evaluated and good results are obtained. The same EnKF framework with attenuation correction is used to test different possible configurations of 2 hypothetical radars added to the existing network of 4 CASA radars through OSSEs. Though plans to expand the CASA radar network did not materialize, such experiments can provide guidance in the site selection of future X-band or other short-wavelength radar networks, as well as examining the benefit of X-band radar networks that consist of a much larger number of radars. Two QLCSs with different propagation speeds are generated and serve as the truth for our OSSEs. Assimilation and forecast results are compared among the OSSEs, assimilating only X-band or short-wavelength radar data. Overall, radar networks with larger downstream spatial coverage tend to provide overall the best analyses and 1-hour forecasts. The best analyses and forecasts of convective scale structure, however, are obtained when Dual- or Multi-Doppler coverage is preferred, even at the expense of minor loss in spatial coverage. Built-in attenuation correction is then applied, for the first time, to a real case (the 24 May 2011 tornadic storm near Chickasha, Oklahoma), using data from the X-band CASA radars. The attenuation correction procedure is found to be very effective---the analyses obtained using attenuated data are better than those obtained using pre-corrected data when all the values of reflectivity observations are assimilated. The effectiveness of the procedure is further examined by comparing the deterministic and ensemble forecasts started from the analysis of each experiment. The deterministic forecast experiment results indicate that assimilating un-corrected observations directly actually retains some information that might be lost in the pre-corrected CASA observations by forecasting a longer-lasting trailing line, similar to that observed in WSR-88D data. In the ensemble forecasts, assimilating un-corrected observations directly, using our attenuation-correcting EnKF, results in a forecast with a more intense tornado track than the experiment that assimilates all values of pre-corrected CASA data. This work is the first to assimilate attenuated observations from a radar network in OSSEs, as well as the first attempt to directly assimilate real, uncorrected CASA data into a numerical weather prediction (NWP) model using EnKF.
Multispectral Imager With Improved Filter Wheel and Optics
NASA Technical Reports Server (NTRS)
Bremer, James C.
2007-01-01
Figure 1 schematically depicts an improved multispectral imaging system of the type that utilizes a filter wheel that contains multiple discrete narrow-band-pass filters and that is rotated at a constant high speed to acquire images in rapid succession in the corresponding spectral bands. The improvement, relative to prior systems of this type, consists of the measures taken to prevent the exposure of a focal-plane array (FPA) of photodetectors to light in more than one spectral band at any given time and to prevent exposure of the array to any light during readout. In prior systems, these measures have included, variously the use of mechanical shutters or the incorporation of wide opaque sectors (equivalent to mechanical shutters) into filter wheels. These measures introduce substantial dead times into each operating cycle intervals during which image information cannot be collected and thus incoming light is wasted. In contrast, the present improved design does not involve shutters or wide opaque sectors, and it reduces dead times substantially. The improved multispectral imaging system is preceded by an afocal telescope and includes a filter wheel positioned so that its rotation brings each filter, in its turn, into the exit pupil of the telescope. The filter wheel contains an even number of narrow-band-pass filters separated by narrow, spoke-like opaque sectors. The geometric width of each filter exceeds the cross-sectional width of the light beam coming out of the telescope. The light transmitted by the sequence of narrow-band filters is incident on a dichroic beam splitter that reflects in a broad shorter-wavelength spectral band that contains half of the narrow bands and transmits in a broad longer-wavelength spectral band that contains the other half of the narrow spectral bands. The filters are arranged on the wheel so that if the pass band of a given filter is in the reflection band of the dichroic beam splitter, then the pass band of the adjacent filter is in the longer-wavelength transmission band of the dichroic beam splitter (see Figure 2). Each of the two optical paths downstream of the dichroic beam splitter contains an additional broad-band-pass filter: The filter in the path of the light transmitted by the dichroic beam splitter transmits and attenuates in the same bands that are transmitted and reflected, respectively, by the beam splitter; the filter in the path of the light reflected by the dichroic beam splitter transmits and attenuates in the same bands that are reflected and transmitted, respectively, by the dichroic beam splitter. In each of these paths, the filtered light is focused onto an FPA. As the filter wheel rotates at a constant angular speed, its shaft angle is monitored, and the shaft-angle signal is used to synchronize the exposure times of the two FPAs. When a single narrowband-pass filter on the wheel occupies the entire cross section of the beam of light coming out of the telescope, the spectrum of light that reaches the dichroic beam splitter lies entirely within the pass band of that filter. Therefore, the beam in its entirety is either transmitted by the dichroic beam splitter and imaged on the longer-wavelength FPA or reflected by the beam splitter and imaged onto the shorter-wavelength FPA.
Liu, Peilu; Li, Xinghua; Li, Haopeng; Su, Zhikun; Zhang, Hongxu
2017-01-01
In order to improve the accuracy of ultrasonic phased array focusing time delay, analyzing the original interpolation Cascade-Integrator-Comb (CIC) filter, an 8× interpolation CIC filter parallel algorithm was proposed, so that interpolation and multichannel decomposition can simultaneously process. Moreover, we summarized the general formula of arbitrary multiple interpolation CIC filter parallel algorithm and established an ultrasonic phased array focusing time delay system based on 8× interpolation CIC filter parallel algorithm. Improving the algorithmic structure, 12.5% of addition and 29.2% of multiplication was reduced, meanwhile the speed of computation is still very fast. Considering the existing problems of the CIC filter, we compensated the CIC filter; the compensated CIC filter’s pass band is flatter, the transition band becomes steep, and the stop band attenuation increases. Finally, we verified the feasibility of this algorithm on Field Programming Gate Array (FPGA). In the case of system clock is 125 MHz, after 8× interpolation filtering and decomposition, time delay accuracy of the defect echo becomes 1 ns. Simulation and experimental results both show that the algorithm we proposed has strong feasibility. Because of the fast calculation, small computational amount and high resolution, this algorithm is especially suitable for applications with high time delay accuracy and fast detection. PMID:29023385
Optimal Recursive Digital Filters for Active Bending Stabilization
NASA Technical Reports Server (NTRS)
Orr, Jeb S.
2013-01-01
In the design of flight control systems for large flexible boosters, it is common practice to utilize active feedback control of the first lateral structural bending mode so as to suppress transients and reduce gust loading. Typically, active stabilization or phase stabilization is achieved by carefully shaping the loop transfer function in the frequency domain via the use of compensating filters combined with the frequency response characteristics of the nozzle/actuator system. In this paper we present a new approach for parameterizing and determining optimal low-order recursive linear digital filters so as to satisfy phase shaping constraints for bending and sloshing dynamics while simultaneously maximizing attenuation in other frequency bands of interest, e.g. near higher frequency parasitic structural modes. By parameterizing the filter directly in the z-plane with certain restrictions, the search space of candidate filter designs that satisfy the constraints is restricted to stable, minimum phase recursive low-pass filters with well-conditioned coefficients. Combined with optimal output feedback blending from multiple rate gyros, the present approach enables rapid and robust parametrization of autopilot bending filters to attain flight control performance objectives. Numerical results are presented that illustrate the application of the present technique to the development of rate gyro filters for an exploration-class multi-engined space launch vehicle.
Aymerich, I; Acuña, V; Barceló, D; García, M J; Petrovic, M; Poch, M; Rodriguez-Mozaz, S; Rodríguez-Roda, I; Sabater, S; von Schiller, D; Corominas, Ll
2016-09-01
Pharmaceuticals are designed to improve human and animal health, but may also be a threat to freshwater ecosystems, particularly after receiving urban or wastewater treatment plant (WWTP) effluents. Knowledge on the fate and attenuation of pharmaceuticals in engineered and natural ecosystems is rather fragmented, and comparable methods are needed to facilitate the comprehension of those processes amongst systems. In this study the dynamics of 8 pharmaceuticals (acetaminophen, sulfapyridine, sulfamethoxazole, carbamazepine, venlafaxine, ibuprofen, diclofenac, diazepam) and 11 of their transformation products were investigated in a WWTP and the associated receiving river ecosystem. During 3 days, concentrations of these compounds were quantified at the influents, effluents, and wastage of the WWTP, and at different distances downstream the effluent at the river. Attenuation (net balance between removal and release from and to the water column) was estimated in both engineered and natural systems using a comparable model-based approach by considering different uncertainty sources (e.g. chemical analysis, sampling, and flow measurements). Results showed that pharmaceuticals load reduction was higher in the WWTP, but attenuation efficiencies (as half-life times) were higher in the river. In particular, the load of only 5 out of the 19 pharmaceuticals was reduced by more than 90% at the WWTP, while the rest were only partially or non-attenuated (or released) and discharged into the receiving river. At the river, only the load of ibuprofen was reduced by more than 50% (out of the 6 parent compounds present in the river), while partial and non-attenuation (or release) was observed for some of their transformation products. Linkages in the routing of some pharmaceuticals (venlafaxine, carbamazepine, ibuprofen and diclofenac) and their corresponding transformation products were also identified at both WWTP and river. Finally, the followed procedure showed that dynamic attenuation in the coupled WWTP-river system could be successfully predicted with simple first order attenuation kinetics for most modeled compounds. Copyright © 2016 Elsevier Ltd. All rights reserved.
Saltiel, Seth; Bonner, Brian P.; Ajo-Franklin, Jonathan B.
2017-05-05
Measurements of nonlinear modulus and attenuation of fractures provide the opportunity to probe their mechanical state. We have adapted a low-frequency torsional apparatus to explore the seismic signature of fractures under low normal stress, simulating low effective stress environments such as shallow or high pore pressure reservoirs. We report strain-dependent modulus and attenuation for fractured samples of Duperow dolomite (a carbon sequestration target reservoir in Montana), Blue Canyon Dome rhyolite (a geothermal analog reservoir in New Mexico), and Montello granite (a deep basement disposal analog from Wisconsin). We use a simple single effective asperity partial slip model to fit ourmore » measured stress-strain curves, and solve for the friction coefficient, contact radius, and full slip condition. These observations have the potential to develop into new field techniques for measuring differences in frictional properties during reservoir engineering manipulations and estimate the stress conditions where reservoir fractures and faults begin to fully slip.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Saltiel, Seth; Bonner, Brian P.; Ajo-Franklin, Jonathan B.
Measurements of nonlinear modulus and attenuation of fractures provide the opportunity to probe their mechanical state. We have adapted a low-frequency torsional apparatus to explore the seismic signature of fractures under low normal stress, simulating low effective stress environments such as shallow or high pore pressure reservoirs. We report strain-dependent modulus and attenuation for fractured samples of Duperow dolomite (a carbon sequestration target reservoir in Montana), Blue Canyon Dome rhyolite (a geothermal analog reservoir in New Mexico), and Montello granite (a deep basement disposal analog from Wisconsin). We use a simple single effective asperity partial slip model to fit ourmore » measured stress-strain curves, and solve for the friction coefficient, contact radius, and full slip condition. These observations have the potential to develop into new field techniques for measuring differences in frictional properties during reservoir engineering manipulations and estimate the stress conditions where reservoir fractures and faults begin to fully slip.« less
Human attention filters for single colors.
Sun, Peng; Chubb, Charles; Wright, Charles E; Sperling, George
2016-10-25
The visual images in the eyes contain much more information than the brain can process. An important selection mechanism is feature-based attention (FBA). FBA is best described by attention filters that specify precisely the extent to which items containing attended features are selectively processed and the extent to which items that do not contain the attended features are attenuated. The centroid-judgment paradigm enables quick, precise measurements of such human perceptual attention filters, analogous to transmission measurements of photographic color filters. Subjects use a mouse to locate the centroid-the center of gravity-of a briefly displayed cloud of dots and receive precise feedback. A subset of dots is distinguished by some characteristic, such as a different color, and subjects judge the centroid of only the distinguished subset (e.g., dots of a particular color). The analysis efficiently determines the precise weight in the judged centroid of dots of every color in the display (i.e., the attention filter for the particular attended color in that context). We report 32 attention filters for single colors. Attention filters that discriminate one saturated hue from among seven other equiluminant distractor hues are extraordinarily selective, achieving attended/unattended weight ratios >20:1. Attention filters for selecting a color that differs in saturation or lightness from distractors are much less selective than attention filters for hue (given equal discriminability of the colors), and their filter selectivities are proportional to the discriminability distance of neighboring colors, whereas in the same range hue attention-filter selectivity is virtually independent of discriminabilty.
A target detection multi-layer matched filter for color and hyperspectral cameras
NASA Astrophysics Data System (ADS)
Miyanishi, Tomoya; Preece, Bradley L.; Reynolds, Joseph P.
2018-05-01
In this article, a method for applying matched filters to a 3-dimentional hyperspectral data cube is discussed. In many applications, color visible cameras or hyperspectral cameras are used for target detection where the color or spectral optical properties of the imaged materials are partially known in advance. Therefore, the use of matched filtering with spectral data along with shape data is an effective method for detecting certain targets. Since many methods for 2D image filtering have been researched, we propose a multi-layer filter where ordinary spatially matched filters are used before the spectral filters. We discuss a way to layer the spectral filters for a 3D hyperspectral data cube, accompanied by a detectability metric for calculating the SNR of the filter. This method is appropriate for visible color cameras and hyperspectral cameras. We also demonstrate an analysis using the Night Vision Integrated Performance Model (NV-IPM) and a Monte Carlo simulation in order to confirm the effectiveness of the filtering in providing a higher output SNR and a lower false alarm rate.
An apparatus to measure water optical attenuation length for LHAASO-MD
NASA Astrophysics Data System (ADS)
Li, Cong; Xiao, Gang; Feng, Shaohui; Wang, Lingyu; Li, Xiurong; Zuo, Xiong; Cheng, Ning; Wang, Hui; Gao, Bo; Duan, Zhihao; Liu, Jia; He, Huihai; Saeed, Mohsin; Lhaaso Collaboration
2018-06-01
The large high altitude air shower observatory (LHAASO) is being constructed at 4400 m a.s.l. in Daocheng, Sichuan Province, aiming to reveal the secrets of cosmic rays origin. And it has the largest surface muon detector array in the world. Due to the needs of calibration and construction of muon detector, we developed a water optical attenuation measurement device using an 8 m long water tank. The results are presented for filtered water at wavelength of 405 nm, which proves this apparatus can reach an accuracy of about 20% at 100 m. This apparatus has not only a high precision measurement of water attenuation length up to 100 m but is also very convenient to be used, which is crucial for water optical properties study during LHAASO detector construction.
Optimization of a matched-filter receiver for frequency hopping code acquisition in jamming
NASA Astrophysics Data System (ADS)
Pawlowski, P. R.; Polydoros, A.
A matched-filter receiver for frequency hopping (FH) code acquisition is optimized when either partial-band tone jamming or partial-band Gaussian noise jamming is present. The receiver is matched to a segment of the FH code sequence, sums hard per-channel decisions to form a test, and uses multiple tests to verify acquisition. The length of the matched filter and the number of verification tests are fixed. Optimization is then choosing thresholds to maximize performance based upon the receiver's degree of knowledge about the jammer ('side-information'). Four levels of side-information are considered, ranging from none to complete. The latter level results in a constant-false-alarm-rate (CFAR) design. At each level, performance sensitivity to threshold choice is analyzed. Robust thresholds are chosen to maximize performance as the jammer varies its power distribution, resulting in simple design rules which aid threshold selection. Performance results, which show that optimum distributions for the jammer power over the total FH bandwidth exist, are presented.
3D early embryogenesis image filtering by nonlinear partial differential equations.
Krivá, Z; Mikula, K; Peyriéras, N; Rizzi, B; Sarti, A; Stasová, O
2010-08-01
We present nonlinear diffusion equations, numerical schemes to solve them and their application for filtering 3D images obtained from laser scanning microscopy (LSM) of living zebrafish embryos, with a goal to identify the optimal filtering method and its parameters. In the large scale applications dealing with analysis of 3D+time embryogenesis images, an important objective is a correct detection of the number and position of cell nuclei yielding the spatio-temporal cell lineage tree of embryogenesis. The filtering is the first and necessary step of the image analysis chain and must lead to correct results, removing the noise, sharpening the nuclei edges and correcting the acquisition errors related to spuriously connected subregions. In this paper we study such properties for the regularized Perona-Malik model and for the generalized mean curvature flow equations in the level-set formulation. A comparison with other nonlinear diffusion filters, like tensor anisotropic diffusion and Beltrami flow, is also included. All numerical schemes are based on the same discretization principles, i.e. finite volume method in space and semi-implicit scheme in time, for solving nonlinear partial differential equations. These numerical schemes are unconditionally stable, fast and naturally parallelizable. The filtering results are evaluated and compared first using the Mean Hausdorff distance between a gold standard and different isosurfaces of original and filtered data. Then, the number of isosurface connected components in a region of interest (ROI) detected in original and after the filtering is compared with the corresponding correct number of nuclei in the gold standard. Such analysis proves the robustness and reliability of the edge preserving nonlinear diffusion filtering for this type of data and lead to finding the optimal filtering parameters for the studied models and numerical schemes. Further comparisons consist in ability of splitting the very close objects which are artificially connected due to acquisition error intrinsically linked to physics of LSM. In all studied aspects it turned out that the nonlinear diffusion filter which is called geodesic mean curvature flow (GMCF) has the best performance. Copyright 2010 Elsevier B.V. All rights reserved.
The effect of different methods of leucoreduction on plasma coagulation factors.
Aboul Enein, Azza A; Abdel Rahman, Hala A; Abdel Maged, Mohamed M M; El Sissy, Maha H
2017-03-01
Removal of leucocytes from blood products, namely leucoreduction, improves the safety of blood transfusion by reducing adverse events associated with the incidental transfusion of leucocytes. Coagulation factors might be compromised during leucoreduction because of exposure of plasma to a variety of filter materials. The aim of the current study was to assess the effect of different methods of prestorage leucofiltration (apheresis and whole blood filters) on prothrombin time, international normalized ratio, partial thromboplastin time and factors V and VIII. There was a significant prolongation of prothrombin time as well as elevation of international normalized ratio in plasma after leucoreduction (14.5 ± 0.7 s vs. 13.9 ± 0.7 s, P = 0.008 and 1.14 ± 0.07 vs. 1.09 ± 0.07, P = 0.005, respectively). Also, there was a statistically significant prolongation of activated partial thromboplastin time in nonleucoreduced plasma (55.6 ± 9.9 s vs. 43.2 ± 12.8 s, P = 0.001). There was no significant filtration effect on factors V and VIII levels. Furthermore, there was no significant difference in factors V and VIII levels between plasma filtered by inline whole blood filters and apheresis machine. Leucodepleted plasma originating from both inline whole blood filter and apheresis machine maintained satisfactory levels of factors V and VIII.
Hepatic hepcidin gene expression in dogs with a congenital portosystemic shunt.
Frowde, P E; Gow, A G; Burton, C A; Powell, R; Lipscomb, V J; House, A K; Mellanby, R J; Tivers, M S
2014-01-01
Microcytic anemia is common in dogs with a congenital portosystemic shunt (cPSS) and typically resolves after surgical attenuation of the anomalous vessel. However, the pathophysiology of the microcytic anemia remains poorly understood. Hepcidin has been a key role in controlling iron transport in both humans and animals and in mediating anemia of inflammatory disease in humans. The role of hepcidin in the development of microcytic anemia in dogs with a cPSS has not been examined. To determine whether hepatic hepcidin mRNA expression decreases, while red blood cell count (RBC) and mean corpuscular volume (MCV) increase in dogs after surgical attenuation of a cPSS. Eighteen client-owned dogs with confirmed cPSS undergoing surgical attenuation. Prospective study. Red blood cell count (RBC) and mean corpuscular volume (MCV), together with hepatic gene expression of hepcidin, were measured in dogs before and after partial attenuation of a cPSS. There was a significant increase in both RBC (median pre 6.17 × 10(12) /L, median post 7.08 × 10(12) /L, P < .001) and MCV (median pre 61.5fl, median post 65.5fl, P = .006) after partial surgical attenuation of the cPSS. Despite the increase in both measured red blood cell parameters, hepatic gene expression of hepcidin remained unchanged. This study found no evidence that dysregulated production of hepcidin was associated with anemia in dogs with a cPSS. Copyright © 2014 by the American College of Veterinary Internal Medicine.
Optical power-based interrogation of plasmonic tilted fiber Bragg grating biosensors
NASA Astrophysics Data System (ADS)
González-Vila, Á.; Lopez-Aldaba, A.; Kinet, D.; Mégret, P.; Lopez-Amo, M.; Caucheteur, C.
2017-04-01
Two interrogation techniques for plasmonic tilted fiber Bragg grating sensors are reported and experimentally tested. Typical interrogation methods are usually based on tracking the wavelength shift of the most sensitive cladding mode, but for biosensing applications, spectrometer-based methods can be replaced by more efficient solutions. The proposed techniques thus rely on the measurement of the induced changes in optical power. The first one consists of a properly polarized tunable laser source set to emit at the wavelength of the sensor most sensitive mode and an optical power meter to measure the transmitted response. For the second method, a uniform fiber Bragg grating is photo-inscribed beyond the sensor in such a way that its central wavelength matches the sensor most sensitive mode, acting as an optical filter. Using a LED source, light reflected backwards by this grating is partially attenuated when passing through the sensor due to plasmon wave excitation and the power changes are quantified once again with an optical power meter. A performance analysis of the techniques is carried out and they both result competitive interrogation solutions. The work thus focuses on the development of cost-effective alternatives for monitoring this kind of biosensors in practical situations.
Beam Attenuators and the Risk of Unrecognized Large-Fraction Irradiation of Critical Tissues
DOE Office of Scientific and Technical Information (OSTI.GOV)
Luka, S.; Marks, J.E.
2015-01-15
The use of radiation beam attenuators led to radiation injury of the spinal cord in one patient and of the peripheral nerve in another due to unsuspected large-fraction irradiation. The anatomic distribution of radiation dose was reconstructed in the sagittal plane for the patient who developed radiation myelopathy and in the axial plane for the patient who developed peripheral neuropathy. The actual dose delivered to the injured structure in each patient was taken from the dose distribution and recorded along with the time, number of fractions, and dose per fraction. The patient who developed radiation myelopathy received a total ofmore » 46.5 Gy in twenty-three 2.1 Gy fractions in 31 days to the upper cervical spinal cord where the thickness of the neck was less than the central axis thickness due to cervical lordosis and absence of a posterior compensating filter. The patient who developed peripheral neuropathy received 55 Gy in twenty-five 2.2 Gy fractions in 50 days to the femoral nerve using bolus over the groins and an anterior one-half value layer Cerrobend pelvic block to bias the dose anteriorly. Compensating filters and other beam attenuators should be used with caution because they may result in unsuspected large-fraction irradiation and total doses of radiation that exceed the tolerance of critical structures.« less
Design of microstrip components by computer
NASA Technical Reports Server (NTRS)
Cisco, T. C.
1972-01-01
A number of computer programs are presented for use in the synthesis of microwave components in microstrip geometries. The programs compute the electrical and dimensional parameters required to synthesize couplers, filters, circulators, transformers, power splitters, diode switches, multipliers, diode attenuators and phase shifters. Additional programs are included to analyze and optimize cascaded transmission lines and lumped element networks, to analyze and synthesize Chebyshev and Butterworth filter prototypes, and to compute mixer intermodulation products. The programs are written in FORTRAN and the emphasis of the study is placed on the use of these programs and not on the theoretical aspects of the structures.
Analysis of signals propagating in a phononic crystal PZT layer deposited on a silicon substrate.
Hladky-Hennion, Anne-Christine; Vasseur, Jérôme; Dubus, Bertrand; Morvan, Bruno; Wilkie-Chancellier, Nicolas; Martinez, Loïc
2013-12-01
The design of a stop-band filter constituted by a periodically patterned lead zirconate titanate (PZT) layer, polarized along its thickness, deposited on a silicon substrate and sandwiched between interdigitated electrodes for emission/reception of guided elastic waves, is investigated. The filter characteristics are theoretically evaluated by using finite element simulations: dispersion curves of a patterned PZT layer with a specific pattern geometry deposited on a silicon substrate present an absolute stop band. The whole structure is modeled with realistic conditions, including appropriate interdigitated electrodes to propagate a guided mode in the piezoelectric layer. A robust method for signal analysis based on the Gabor transform is applied to treat transmitted signals; extract attenuation, group delays, and wave number variations versus frequency; and identify stop-band filter characteristics.
SU8 inverted-rib waveguide Bragg grating filter.
Huang, Cheng-Sheng; Wang, Wei-Chih
2013-08-01
A polymeric SU8 inverted-rib waveguide Bragg grating filter fabricated using reactive ion etching (RIE) and solvent assisted microcontact molding (SAMIM) is presented. SAMIM is one kind of soft lithography. The technique is unique in that a composite hard-polydimethysiloxane/polydimethysiloxane stamp is used to transfer the grating pattern onto an inverted SU8 rib waveguide system. The composite grating stamp can be used repeatedly several times without degradation. Using this stamp and inverter-rib waveguide structure, the Bragg grating filter fabrication can be significantly simplified. The experiment result shows an attenuation dip in the transmission spectra, with a value of -7 dBm at 1550 nm for a grating with a period of 0.492 μm on an inverted-rib waveguide with 6.6 μm width and 4 μm height.
NASA Technical Reports Server (NTRS)
Subramanyam, Guru; Vignesparamoorthy, Sivaruban; Mueller, Carl; VanKeuls, Fred; Warner, Joseph; Miranda, Felix A.
2001-01-01
The main purpose of this work is to study the effect of a selectively etched ferroelectric thin film layer on the performance of an electrically tunable filter. An X-band tunable filter was designed, fabricated and tested on a selectively etched Barium Strontium Titanate (BSTO) ferroelectric thin film layer. Tunable filters with varying lengths of BSTO thin-film in the input and output coupling gaps were modeled, as well as experimentally tested. Experimental results showed that filters with coupling gaps partially filled with BSTO maintained frequency tunability and improved the insertion loss by approx. 2dB. To the best of our knowledge, these results represent the first experimental demonstration of the advantages of selective etching in the performance of thin film ferroelectric-based tunable microwave components.
On the concept of a filtered bundle
NASA Astrophysics Data System (ADS)
Bruce, Andrew James; Grabowska, Katarzyna; Grabowski, Janusz
We present the notion of a filtered bundle as a generalization of a graded bundle. In particular, we weaken the necessity of the transformation laws for local coordinates to exactly respect the weight of the coordinates by allowing more general polynomial transformation laws. The key examples of such bundles include affine bundles and various jet bundles, both of which play fundamental roles in geometric mechanics and classical field theory. We also present the notion of double filtered bundles which provide natural generalizations of double vector bundles and double affine bundles. Furthermore, we show that the linearization of a filtered bundle — which can be seen as a partial polarization of the admissible changes of local coordinates — is well defined.
Banerjee, Biswanath; Roy, Debasish; Vasu, Ram Mohan
2009-08-01
A computationally efficient pseudodynamical filtering setup is established for elasticity imaging (i.e., reconstruction of shear modulus distribution) in soft-tissue organs given statically recorded and partially measured displacement data. Unlike a regularized quasi-Newton method (QNM) that needs inversion of ill-conditioned matrices, the authors explore pseudodynamic extended and ensemble Kalman filters (PD-EKF and PD-EnKF) that use a parsimonious representation of states and bypass explicit regularization by recursion over pseudotime. Numerical experiments with QNM and the two filters suggest that the PD-EnKF is the most robust performer as it exhibits no sensitivity to process noise covariance and yields good reconstruction even with small ensemble sizes.
Rodgers, Billy R.; Edwards, Michael S.
1977-01-01
Solids such as char, ash, and refractory organic compounds are removed from coal-derived liquids from coal liquefaction processes by the pressure precoat filtration method using particles of 85-350 mesh material selected from the group of bituminous coal, anthracite coal, lignite, and devolatilized coals as precoat materials and as body feed to the unfiltered coal-derived liquid.
3-D zebrafish embryo image filtering by nonlinear partial differential equations.
Rizzi, Barbara; Campana, Matteo; Zanella, Cecilia; Melani, Camilo; Cunderlik, Robert; Krivá, Zuzana; Bourgine, Paul; Mikula, Karol; Peyriéras, Nadine; Sarti, Alessandro
2007-01-01
We discuss application of nonlinear PDE based methods to filtering of 3-D confocal images of embryogenesis. We focus on the mean curvature driven and the regularized Perona-Malik equations, where standard as well as newly suggested edge detectors are used. After presenting the related mathematical models, the practical results are given and discussed by visual inspection and quantitatively using the mean Hausdorff distance.
Simultaneous processing of photographic and accelerator array data from sled impact experiment
NASA Astrophysics Data System (ADS)
Ash, M. E.
1982-12-01
A Quaternion-Kalman filter model is derived to simultaneously analyze accelerometer array and photographic data from sled impact experiments. Formulas are given for the quaternion representation of rotations, the propagation of dynamical states and their partial derivatives, the observables and their partial derivatives, and the Kalman filter update of the state given the observables. The observables are accelerometer and tachometer velocity data of the sled relative to the track, linear accelerometer array and photographic data of the subject relative to the sled, and ideal angular accelerometer data. The quaternion constraints enter through perfect constraint observations and normalization after a state update. Lateral and fore-aft impact tests are analyzed with FORTRAN IV software written using the formulas of this report.
Bates, Mary E; Simmons, James A
2010-08-01
Big brown bats emit FM biosonar sounds containing two principal harmonics (FM1 approximately 55-22 kHz;FM2 approximately 105-45 kHz). To examine the role of harmonics, they were selectively filtered from stimuli in electronic-echo delay discrimination experiments. Positive stimuli were delayed by 3.16 ms (55 cm simulated target range); negative stimuli were by delayed by 3.96 ms (68 cm). This large 800-micros delay difference (nearly 14 cm) was easily discriminated for echoes containing equal-strength FM1 and FM2. Performance gradually decreased as highpass filters removed progressively larger segments from FM1. For echoes with FM2 alone, performance collapsed to chance, but performance remained good for lowpass echoes containing FM1 alone. Attenuation of FM2 by 3 dB relative to FM1 also decreased performance, but shortening electronic delay of the attenuated FM2 by 48 micros counteracted amplitude-latency trading and restored performance. Bats require the auditory representations of FM1 and FM2 to be in temporal register for high delay acuity. Misalignment of neuronal responses degrades acuity, but outright removal of FM2, leaving only FM1, causes little loss of acuity. Functional asymmetry of harmonics reflects lowpass effects from beaming and atmospheric propagation, which leave FM1 intact. It may cooperate with latency shifts to aid in suppression of clutter.
NASA Astrophysics Data System (ADS)
Saturno, Jorge; Pöhlker, Christopher; Massabò, Dario; Brito, Joel; Carbone, Samara; Cheng, Yafang; Chi, Xuguang; Ditas, Florian; Hrabě de Angelis, Isabella; Morán-Zuloaga, Daniel; Pöhlker, Mira L.; Rizzo, Luciana V.; Walter, David; Wang, Qiaoqiao; Artaxo, Paulo; Prati, Paolo; Andreae, Meinrat O.
2017-08-01
Deriving absorption coefficients from Aethalometer attenuation data requires different corrections to compensate for artifacts related to filter-loading effects, scattering by filter fibers, and scattering by aerosol particles. In this study, two different correction schemes were applied to seven-wavelength Aethalometer data, using multi-angle absorption photometer (MAAP) data as a reference absorption measurement at 637 nm. The compensation algorithms were compared to five-wavelength offline absorption measurements obtained with a multi-wavelength absorbance analyzer (MWAA), which serves as a multiple-wavelength reference measurement. The online measurements took place in the Amazon rainforest, from the wet-to-dry transition season to the dry season (June-September 2014). The mean absorption coefficient (at 637 nm) during this period was 1.8 ± 2.1 Mm-1, with a maximum of 15.9 Mm-1. Under these conditions, the filter-loading compensation was negligible. One of the correction schemes was found to artificially increase the short-wavelength absorption coefficients. It was found that accounting for the aerosol optical properties in the scattering compensation significantly affects the absorption Ångström exponent (åABS) retrievals. Proper Aethalometer data compensation schemes are crucial to retrieve the correct åABS, which is commonly implemented in brown carbon contribution calculations. Additionally, we found that the wavelength dependence of uncompensated Aethalometer attenuation data significantly correlates with the åABS retrieved from offline MWAA measurements.
A Game Theoretic Fault Detection Filter
NASA Technical Reports Server (NTRS)
Chung, Walter H.; Speyer, Jason L.
1995-01-01
The fault detection process is modelled as a disturbance attenuation problem. The solution to this problem is found via differential game theory, leading to an H(sub infinity) filter which bounds the transmission of all exogenous signals save the fault to be detected. For a general class of linear systems which includes some time-varying systems, it is shown that this transmission bound can be taken to zero by simultaneously bringing the sensor noise weighting to zero. Thus, in the limit, a complete transmission block can he achieved, making the game filter into a fault detection filter. When we specialize this result to time-invariant system, it is found that the detection filter attained in the limit is identical to the well known Beard-Jones Fault Detection Filter. That is, all fault inputs other than the one to be detected (the "nuisance faults") are restricted to an invariant subspace which is unobservable to a projection on the output. For time-invariant systems, it is also shown that in the limit, the order of the state-space and the game filter can be reduced by factoring out the invariant subspace. The result is a lower dimensional filter which can observe only the fault to be detected. A reduced-order filter can also he generated for time-varying systems, though the computational overhead may be intensive. An example given at the end of the paper demonstrates the effectiveness of the filter as a tool for fault detection and identification.
Mangold, Stefanie; Thomas, Christoph; Fenchel, Michael; Vuust, Morten; Krauss, Bernhard; Ketelsen, Dominik; Tsiflikas, Ilias; Claussen, Claus D; Heuschmid, Martin
2012-07-01
To retrospectively determine which features of urinary calculi are associated with their detection after virtual elimination of contrast medium at dual-energy computed tomographic (CT) urography by using a novel tin filter. The institutional ethics committee approved this retrospective study, with waiver of informed consent. A total of 152 patients were examined with single-energy nonenhanced CT and dual-energy CT urography in the excretory phase (either 140 and 80 kV [n=44] or 140 and 100 kV [n=108], with tin filtration at 140 kV). The contrast medium in the renal pelvis and ureters was virtually removed from excretory phase images by using postprocessing software, resulting in virtual nonenhanced (VNE) images. The sensitivity regarding the detection of calculi on VNE images compared with true nonenhanced (TNE) images was determined, and interrater agreement was evaluated by using the Cohen k test. By using logistic regression, the influences of image noise, attenuation, and stone size, as well as attenuation of the contrast medium, on the stone detection rate were assessed. Threshold values with maximal sensitivity and specificity were calculated by means of receiver operating characteristic analyses. Eighty-seven stones were detected on TNE images; 46 calculi were identified on VNE images (sensitivity, 52.9%). Interrater agreement revealed a κ value of 0.95 with TNE images and 0.91 with VNE data. Size (long-axis diameter, P=.005; short-axis diameter, P=.041) and attenuation (P=.0005) of the calculi and image noise (P=.0031) were significantly associated with the detection rate on VNE images. As threshold values, size larger than 2.9 mm, maximum attenuation of the calculi greater than 387 HU, and image noise less than 20 HU were found. After virtual elimination of contrast medium, large (>2.9 mm) and high-attenuation (>387 HU) calculi can be detected with good reliability; smaller and lower attenuation calculi might be erased from images, especially with increased image noise. © RSNA, 2012.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Miao, J; Fan, J; Gopinatha Pillai, A
Purpose: To further reduce CT dose, a practical sparse-view acquisition scheme is proposed to provide the same attenuation estimation as higher dose for PET imaging in the extended scan field-of-view. Methods: CT scans are often used for PET attenuation correction and can be acquired at very low CT radiation dose. Low dose techniques often employ low tube voltage/current accompanied with a smooth filter before backprojection to reduce CT image noise. These techniques can introduce bias in the conversion from HU to attenuation values, especially in the extended CT scan field-of-view (FOV). In this work, we propose an ultra-low dose CTmore » technique for PET attenuation correction based on sparse-view acquisition. That is, instead of an acquisition of full amount of views, only a fraction of views are acquired. We tested this technique on a 64-slice GE CT scanner using multiple phantoms. CT scan FOV truncation completion was performed based on the published water-cylinder extrapolation algorithm. A number of continuous views per rotation: 984 (full), 246, 123, 82 and 62 have been tested, corresponding to a CT dose reduction of none, 4x, 8x, 12x and 16x. We also simulated sparse-view acquisition by skipping views from the fully-acquired view data. Results: FBP reconstruction with Q. AC filter on reduced views in the full extended scan field-of-view possesses similar image quality to the reconstruction on acquired full view data. The results showed a further potential for dose reduction compared to the full acquisition, without sacrificing any significant attenuation support to the PET. Conclusion: With the proposed sparse-view method, one can potential achieve at least 2x more CT dose reduction compared to the current Ultra-Low Dose (ULD) PET/CT protocol. A pre-scan based dose modulation scheme can be combined with the above sparse-view approaches, which can even further reduce the CT scan dose during a PET/CT exam.« less
Partial removal of correlated noise in thermal imagery
NASA Astrophysics Data System (ADS)
Borel, Christoph C.; Cooke, Bradly J.; Laubscher, Bryan E.
1996-05-01
Correlated noise occurs in many imaging systems such as scanners and push-broom imagers. The sources of correlated noise can be from the detectors, pre-amplifiers and sampling circuits. Correlated noise appears as streaking along the scan direction of a scanner or in the along track direction of a push-broom imager. We have developed algorithms to simulate correlated noise and pre-filter to reduce the amount of streaking while not destroying the scene content. The pre-filter in the Fourier domain consists of the product of two filters. One filter models the correlated noise spectrum, the other is a windowing function, e.g. Gaussian or Hanning window with variable width to block high frequency noise away from the origin of the Fourier Transform of the image data. We have optimized the filter parameters for various scenes and find improvements of the RMS error of the original minus the pre-filtered noisy image.
Application of a three-lens slit spatial filter in high power lasers
NASA Astrophysics Data System (ADS)
Xiong, Han
2018-07-01
Combined with partial parameters in National Ignition Facility, the conceptual design of off-axial four-pass main laser optical system with a three-lens slit spatial filter has been discussed. Since the three-lens slit spatial filter can decline the focal intensity by about 3 orders of magnitudes than that in NIF system, the cutoff frequency in main amplifier cavity can be reduced from 51 × DL to 39 × DL for better beam quality. The main laser system for single beam line can be shortened from 174.7 m to 155.7 m and the spatial filter in high vacuum becomes 60 m instead of the original 83.5 m. Additionally, the pinhole closure could be avoided since the declining of focal intensity in slit spatial filter and the absence of pinhole aperture in the other (pinhole) spatial filter, which provides new ideas for the future high-power lasers.
NASA Technical Reports Server (NTRS)
Kilbourne, C. A.; Adams, J. S.; Arsenovic, P.; Ayers, T.; Chiao, M. P.; DiPirro, M. J.; Eckart, M. E.; Fujimoto, R.; Kazeva, J. D.; Kelley, R. L.;
2016-01-01
The calorimeter array of the JAXA Astro-H (renamed Hitomi) Soft X-ray Spectrometer (SXS) was designed to provide unprecedented spectral resolution of spatially extended cosmic x-ray sources and of all cosmic x-ray sources in the Fe-K band around 6 keV. The properties that make the SXS a powerful x-ray spectrometer also make it sensitive to the entire electromagnetic band. If characterized as a bolometer, it would have a noise equivalent power (NEP) of < 4x10(exp -18) W/(Hz)0.5. Thus it was imperative to shield the detector from thermal radiation from the instrument and optical and UV photons from the sky. Additionally, it was necessary to shield the coldest stages of the instrument from the thermal radiation emanating from the warmer stages. These needs are addressed by a series of five thin-film radiation blocking filters that block long-wavelength radiation while minimizing x-ray attenuation. The SXS aperture assembly is a system of barriers, baffles, filter carriers, and filter mounts that supports the filters and inhibits their potential contamination. The three warmer filters also were equipped with thermometers and heaters for decontamination.
Mcclenny, Levi D; Imani, Mahdi; Braga-Neto, Ulisses M
2017-11-25
Gene regulatory networks govern the function of key cellular processes, such as control of the cell cycle, response to stress, DNA repair mechanisms, and more. Boolean networks have been used successfully in modeling gene regulatory networks. In the Boolean network model, the transcriptional state of each gene is represented by 0 (inactive) or 1 (active), and the relationship among genes is represented by logical gates updated at discrete time points. However, the Boolean gene states are never observed directly, but only indirectly and incompletely through noisy measurements based on expression technologies such as cDNA microarrays, RNA-Seq, and cell imaging-based assays. The Partially-Observed Boolean Dynamical System (POBDS) signal model is distinct from other deterministic and stochastic Boolean network models in removing the requirement of a directly observable Boolean state vector and allowing uncertainty in the measurement process, addressing the scenario encountered in practice in transcriptomic analysis. BoolFilter is an R package that implements the POBDS model and associated algorithms for state and parameter estimation. It allows the user to estimate the Boolean states, network topology, and measurement parameters from time series of transcriptomic data using exact and approximated (particle) filters, as well as simulate the transcriptomic data for a given Boolean network model. Some of its infrastructure, such as the network interface, is the same as in the previously published R package for Boolean Networks BoolNet, which enhances compatibility and user accessibility to the new package. We introduce the R package BoolFilter for Partially-Observed Boolean Dynamical Systems (POBDS). The BoolFilter package provides a useful toolbox for the bioinformatics community, with state-of-the-art algorithms for simulation of time series transcriptomic data as well as the inverse process of system identification from data obtained with various expression technologies such as cDNA microarrays, RNA-Seq, and cell imaging-based assays.
Research on signal processing of shock absorber test bench based on zero-phase filter
NASA Astrophysics Data System (ADS)
Wu, Yi; Ding, Guoqing
2017-10-01
The quality of force-displacement diagram is significant to help evaluate the performance of shock absorbers. Damping force sampling data is often interfered by Gauss white noise, 50Hz power interference and its harmonic wave during the process of testing; data de-noising has become the core problem of drawing true, accurate and real-time indicator diagram. The noise and interference can be filtered out through generic IIR or FIR low-pass filter, but addition phase lag of useful signal will be caused due to the inherent attribute of IIR and FIR filter. The paper uses FRR method to realize zero-phase digital filtering in a software way based on mutual cancellation of phase lag between the forward and reverse sequences after through the filter. High-frequency interference above 40Hz are filtered out completely and noise attenuation is more than -40dB, with no additional phase lag. The method is able to restore the true signal as far as possible. Theoretical simulation and practical test indicate high-frequency noises have been effectively inhibited in multiple typical speed cases, signal-to-noise ratio being greatly improved; the curve in indicator diagram has better smoothness and fidelity. The FRR algorithm has low computational complexity, fast running time, and can be easily transplanted in multiple platforms.
Nørgaard, Louise Solveig; Roslev, Peter
2016-12-01
Grazing by cladocerans can reduce the survival of enteric bacteria associated with fecal pollution. This study examined the potential of Daphnia magna to filter commensal and pathogenic Escherichia coli of human origin. Grazing on commensal and pathogenic bacteria was comparable, but slightly greater at 20 compared to 15 and 25°C. Filtering activity was strongly dependent on D. magna and E. coli densities at environmentally relevant bacterial concentrations. Maximum feeding rates were >10 7 cells h -1 daphnid -1 , clearance rates were 1-6 mL h -1 daphnid -1 , and filtering was independent of bacterial cell sizes between 0.7 and 1.8 µm. Filtering and ingestion of E. coli by D. magna was susceptible to acute inhibition by unionized ammonia with a 24 h EC50 of 0.18 mg L -1 NH 3 -N, and a LOEC of 0.09 mg L -1 NH 3 -N. The study indicated that biological and chemical constraints should be considered when applying Daphnia for attenuation of fecal pollution.
X-ray computed tomography of wood-adhesive bondlines: Attenuation and phase-contrast effects
Paris, Jesse L.; Kamke, Frederick A.; Xiao, Xianghui
2015-07-29
Microscale X-ray computed tomography (XCT) is discussed as a technique for identifying 3D adhesive distribution in wood-adhesive bondlines. Visualization and material segmentation of the adhesives from the surrounding cellular structures require sufficient gray-scale contrast in the reconstructed XCT data. Commercial wood-adhesive polymers have similar chemical characteristics and density to wood cell wall polymers and therefore do not provide good XCT attenuation contrast in their native form. Here, three different adhesive types, namely phenol formaldehyde, polymeric diphenylmethane diisocyanate, and a hybrid polyvinyl acetate, are tagged with iodine such that they yield sufficient X-ray attenuation contrast. However, phase-contrast effects at material edgesmore » complicate image quality and segmentation in XCT data reconstructed with conventional filtered backprojection absorption contrast algorithms. A quantitative phase retrieval algorithm, which isolates and removes the phase-contrast effect, was demonstrated. The paper discusses and illustrates the balance between material X-ray attenuation and phase-contrast effects in all quantitative XCT analyses of wood-adhesive bondlines.« less
An investigation of hydraulic-line resonance and its attenuation
NASA Technical Reports Server (NTRS)
Sewall, J. L.; Wineman, D. A.; Herr, R. W.
1973-01-01
An investigation of fluid resonance in high-pressure hydraulic lines has been made with two types of fluid dampers (or filters) installed in the line. One type involved the use of one or more closed-end tubes branching at right angles from a main line, and the other type was a fluid muffler installed in-line. These devices were evaluated in forced vibration tests with oscillatory disturbances over a 1000-Hz range applied to one end of the line and with oscillatory pressures measured at various stations along the main pipe. Limited applications of acoustic-wave theory to the branched systems are also included. Results show varying attenuations of pressure perturbations, depending on the number and location of branches and the type of muffler. Up to three branches were used in the branch-resonator study, and the largest frequency range with maximum attenuation was obtained for a three-branch configuration. The widest frequency ranges with significant attenuations were obtained with two types of fluid mufflers.
X-ray computed tomography of wood-adhesive bondlines: Attenuation and phase-contrast effects
DOE Office of Scientific and Technical Information (OSTI.GOV)
Paris, Jesse L.; Kamke, Frederick A.; Xiao, Xianghui
Microscale X-ray computed tomography (XCT) is discussed as a technique for identifying 3D adhesive distribution in wood-adhesive bondlines. Visualization and material segmentation of the adhesives from the surrounding cellular structures require sufficient gray-scale contrast in the reconstructed XCT data. Commercial wood-adhesive polymers have similar chemical characteristics and density to wood cell wall polymers and therefore do not provide good XCT attenuation contrast in their native form. Here, three different adhesive types, namely phenol formaldehyde, polymeric diphenylmethane diisocyanate, and a hybrid polyvinyl acetate, are tagged with iodine such that they yield sufficient X-ray attenuation contrast. However, phase-contrast effects at material edgesmore » complicate image quality and segmentation in XCT data reconstructed with conventional filtered backprojection absorption contrast algorithms. A quantitative phase retrieval algorithm, which isolates and removes the phase-contrast effect, was demonstrated. The paper discusses and illustrates the balance between material X-ray attenuation and phase-contrast effects in all quantitative XCT analyses of wood-adhesive bondlines.« less
Evaluation of the OSC-TV iterative reconstruction algorithm for cone-beam optical CT
DOE Office of Scientific and Technical Information (OSTI.GOV)
Matenine, Dmitri, E-mail: dmitri.matenine.1@ulaval.ca; Mascolo-Fortin, Julia, E-mail: julia.mascolo-fortin.1@ulaval.ca; Goussard, Yves, E-mail: yves.goussard@polymtl.ca
Purpose: The present work evaluates an iterative reconstruction approach, namely, the ordered subsets convex (OSC) algorithm with regularization via total variation (TV) minimization in the field of cone-beam optical computed tomography (optical CT). One of the uses of optical CT is gel-based 3D dosimetry for radiation therapy, where it is employed to map dose distributions in radiosensitive gels. Model-based iterative reconstruction may improve optical CT image quality and contribute to a wider use of optical CT in clinical gel dosimetry. Methods: This algorithm was evaluated using experimental data acquired by a cone-beam optical CT system, as well as complementary numericalmore » simulations. A fast GPU implementation of OSC-TV was used to achieve reconstruction times comparable to those of conventional filtered backprojection. Images obtained via OSC-TV were compared with the corresponding filtered backprojections. Spatial resolution and uniformity phantoms were scanned and respective reconstructions were subject to evaluation of the modulation transfer function, image uniformity, and accuracy. The artifacts due to refraction and total signal loss from opaque objects were also studied. Results: The cone-beam optical CT data reconstructions showed that OSC-TV outperforms filtered backprojection in terms of image quality, thanks to a model-based simulation of the photon attenuation process. It was shown to significantly improve the image spatial resolution and reduce image noise. The accuracy of the estimation of linear attenuation coefficients remained similar to that obtained via filtered backprojection. Certain image artifacts due to opaque objects were reduced. Nevertheless, the common artifact due to the gel container walls could not be eliminated. Conclusions: The use of iterative reconstruction improves cone-beam optical CT image quality in many ways. The comparisons between OSC-TV and filtered backprojection presented in this paper demonstrate that OSC-TV can potentially improve the rendering of spatial features and reduce cone-beam optical CT artifacts.« less
SU-C-202-07: Protocol and Hardware for Improved Flood Field Calibration of TrueBeam FFF Cine Imaging
DOE Office of Scientific and Technical Information (OSTI.GOV)
Adamson, J; Faught, A; Yin, F
2016-06-15
Purpose: Flattening filter free photon energies are commonly used for high dose treatments such as SBRT, where localization accuracy is essential. Often, MV cine imaging may be employed to verify correct localization. TrueBeam Electronic Portal Imaging Devices (EPIDs) equipped with the 40×30cm{sup 2} Image Detection Unit (IDU) are prone to image saturation at the image center especially for higher dose rates. While saturation often does not occur for cine imaging during treatment because the beam is attenuated by the patient, the flood field calibration is affected when the standard calibration procedure is followed. Here we describe the hardware and protocolmore » to achieve improved image quality for this model of TrueBeam EPID. Methods: A stainless steel filter of uniform thickness was designed to have sufficient attenuation to avoid panel saturation for both 6XFFF and 10XFFF at the maximum dose rates (1400 MU/min & 2400 MU/min, respectively). The cine imaging flood field calibration was then acquired with the filter in place for the FFF energies under the standard calibration geometry (SDD=150cm). Image quality during MV cine was assessed with & without the modified flood field calibration using a low contrast resolution phantom and an anthropomorphic phantom. Results: When the flood field is acquired using the standard procedure (no filter in place), a pixel gain artifact is clearly present in the image center (r=3cm for 10XFFF at 2400 MU/min) which appears similar to and may be mis-attributed to panel saturation in the subject image. The artifact obscured all low contrast inserts at the image center and was also visible on the anthropomorphic phantom. Using the filter for flood field calibration eliminated the artifact. Conclusion: Use of a modified flood field calibration procedure improves image quality for cine MV imaging with TrueBeams equipped with the 40×30cm{sup 2} IDU.« less
Evaluation of the OSC-TV iterative reconstruction algorithm for cone-beam optical CT.
Matenine, Dmitri; Mascolo-Fortin, Julia; Goussard, Yves; Després, Philippe
2015-11-01
The present work evaluates an iterative reconstruction approach, namely, the ordered subsets convex (OSC) algorithm with regularization via total variation (TV) minimization in the field of cone-beam optical computed tomography (optical CT). One of the uses of optical CT is gel-based 3D dosimetry for radiation therapy, where it is employed to map dose distributions in radiosensitive gels. Model-based iterative reconstruction may improve optical CT image quality and contribute to a wider use of optical CT in clinical gel dosimetry. This algorithm was evaluated using experimental data acquired by a cone-beam optical CT system, as well as complementary numerical simulations. A fast GPU implementation of OSC-TV was used to achieve reconstruction times comparable to those of conventional filtered backprojection. Images obtained via OSC-TV were compared with the corresponding filtered backprojections. Spatial resolution and uniformity phantoms were scanned and respective reconstructions were subject to evaluation of the modulation transfer function, image uniformity, and accuracy. The artifacts due to refraction and total signal loss from opaque objects were also studied. The cone-beam optical CT data reconstructions showed that OSC-TV outperforms filtered backprojection in terms of image quality, thanks to a model-based simulation of the photon attenuation process. It was shown to significantly improve the image spatial resolution and reduce image noise. The accuracy of the estimation of linear attenuation coefficients remained similar to that obtained via filtered backprojection. Certain image artifacts due to opaque objects were reduced. Nevertheless, the common artifact due to the gel container walls could not be eliminated. The use of iterative reconstruction improves cone-beam optical CT image quality in many ways. The comparisons between OSC-TV and filtered backprojection presented in this paper demonstrate that OSC-TV can potentially improve the rendering of spatial features and reduce cone-beam optical CT artifacts.
Mise au point d'un bouchon d'oreille "intelligent"
NASA Astrophysics Data System (ADS)
Voix, Jeremie
Many workers are exposed to noise levels high enough to put them at risk of losing their hearing. However, noise reduction at the source, when technically feasible, is often difficult to implement for economical reasons. Therefore, individual hearing protection remains the most widespread solution in practice. Unfortunately, the hearing protectors currently available on the market are seldom worn continuously as they should be (because they are not very comfortable or must be removed to communicate) and do not match the worker's need for protection (because their actual attenuation is generally unknown). This doctorate thesis work, carried out in close collaboration with SONOMAX HEARING HEALTHCARE I NC., had the general objective to develop a smart earplug that would solve the problems associated with current hearing protection devices thereby effectively preventing noise induced hearing loss in the industrial environment. The issues associated to this development have been formulated in details under the Health and Safety aspect (non-continuous wearing of the hearing protector and un-adapted protection), technical aspects (development of an earplug that is comfortable both from the physical and sound perception points of view and whose performances are measurable) and scientific aspects (modeling of physical systems, signal processing, instrumentation and measurement techniques). The technical developments have resulted in a custom earplug that is instantly fitted to the wearer's ear by silicone injection. Its acoustical performance can be measured using a microphone probe while the attenuation can be adapted to the user's need by the insertion through the earplug of passive acoustical filters. The scientific developments have resulted in the prediction of the attenuation of the earplug from the Noise Reduction measurement and in the prediction of the filtered earplug attenuation.
Experimentally determined spectral optimization for dedicated breast computed tomography.
Prionas, Nicolas D; Huang, Shih-Ying; Boone, John M
2011-02-01
The current study aimed to experimentally identify the optimal technique factors (x-ray tube potential and added filtration material/thickness) to maximize soft-tissue contrast, microcalcification contrast, and iodine contrast enhancement using cadaveric breast specimens imaged with dedicated breast computed tomography (bCT). Secondarily, the study aimed to evaluate the accuracy of phantom materials as tissue surrogates and to characterize the change in accuracy with varying bCT technique factors. A cadaveric breast specimen was acquired under appropriate approval and scanned using a prototype bCT scanner. Inserted into the specimen were cylindrical inserts of polyethylene, water, iodine contrast medium (iodixanol, 2.5 mg/ml), and calcium hydroxyapatite (100 mg/ml). Six x-ray tube potentials (50, 60, 70, 80, 90, and 100 kVp) and three different filters (0.2 mm Cu, 1.5 mm Al, and 0.2 mm Sn) were tested. For each set of technique factors, the intensity (linear attenuation coefficient) and noise were measured within six regions of interest (ROIs): Glandular tissue, adipose tissue, polyethylene, water, iodine contrast medium, and calcium hydroxyapatite. Dose-normalized contrast to noise ratio (CNRD) was measured for pairwise comparisons among the six ROIs. Regression models were used to estimate the effect of tube potential and added filtration on intensity, noise, and CNRD. Iodine contrast enhancement was maximized using 60 kVp and 0.2 mm Cu. Microcalcification contrast and soft-tissue contrast were maximized at 60 kVp. The 0.2 mm Cu filter achieved significantly higher CNRD for iodine contrast enhancement than the other two filters (p = 0.01), but microcalcification contrast and soft-tissue contrast were similar using the copper and aluminum filters. The average percent difference in linear attenuation coefficient, across all tube potentials, for polyethylene versus adipose tissue was 1.8%, 1.7%, and 1.3% for 0.2 mm Cu, 1.5 mm Al, and 0.2 mm Sn, respectively. For water versus glandular tissue, the average percent difference was 2.7%, 3.9%, and 4.2% for the three filter types. Contrast-enhanced bCT, using injected iodine contrast medium, may be optimized for maximum contrast of enhancing lesions at 60 kVp with 0.2 mm Cu filtration. Soft-tissue contrast and microcalcification contrast may also benefit from lower tube potentials (60 kVp). The linear attenuation coefficients of water and polyethylene slightly overestimate the values of their corresponding tissues, but the reported differences may serve as guidance for dosimetry and quality assurance using tissue equivalent phantoms.
Elsohaby, Ibrahim; McClure, J Trenton; Riley, Christopher B; Bryanton, Janet; Bigsby, Kathryn; Shaw, R Anthony
2018-02-20
Attenuated total reflectance infrared (ATR-IR) spectroscopy is a simple, rapid and cost-effective method for the analysis of serum. However, the complex nature of serum remains a limiting factor to the reliability of this method. We investigated the benefits of coupling the centrifugal ultrafiltration with ATR-IR spectroscopy for quantification of human serum IgA concentration. Human serum samples (n = 196) were analyzed for IgA using an immunoturbidimetric assay. ATR-IR spectra were acquired for whole serum samples and for the retentate (residue) reconstituted with saline following 300 kDa centrifugal ultrafiltration. IR-based analytical methods were developed for each of the two spectroscopic datasets, and the accuracy of each of the two methods compared. Analytical methods were based upon partial least squares regression (PLSR) calibration models - one with 5-PLS factors (for whole serum) and the second with 9-PLS factors (for the reconstituted retentate). Comparison of the two sets of IR-based analytical results to reference IgA values revealed improvements in the Pearson correlation coefficient (from 0.66 to 0.76), and the root mean squared error of prediction in IR-based IgA concentrations (from 102 to 79 mg/dL) for the ultrafiltration retentate-based method as compared to the method built upon whole serum spectra. Depleting human serum low molecular weight proteins using a 300 kDa centrifugal filter thus enhances the accuracy IgA quantification by ATR-IR spectroscopy. Further evaluation and optimization of this general approach may ultimately lead to routine analysis of a range of high molecular-weight analytical targets that are otherwise unsuitable for IR-based analysis. Copyright © 2017 Elsevier B.V. All rights reserved.
In vitro evaluation of clot capture efficiency of an absorbable vena cava filter.
Dria, Stephen J; Eggers, Mitchell D
2016-10-01
The purpose of this study was to determine the in vitro clot capture efficiency (CCE) of an investigational absorbable inferior vena cava filter (IVCF) vs the Greenfield IVCF. Investigational absorbable and Greenfield filters were challenged with polyacrylamide clot surrogates ranging from 3 × 5 to 10 × 24 mm (diameter × length) in a flow loop simulating the venous system. Filters were challenged with clots until CCE standard error of 5% or less was achieved under binomial statistics. Pressure gradients across the filters were measured for the largest size clot, enabling calculation of forces on the filter. The in vitro CCE of the absorbable IVCF was statistically similar to that of the Greenfield filter for all clot sizes apart from the 3 × 10-mm clot, for which there was statistically significant difference between filter CCEs (absorbable filter, 59%; Greenfield filter, 31%; P = .0001). CCE ranged from an average 32% for the 3 × 5-mm clot to 100% for 7 × 10-mm and larger clots for the absorbable IVCF. Pressure gradient across the absorbable filter with 10 × 24-mm clot averaged 0.14 mm Hg, corresponding to a net force on the filter of 2.1 × 10(-3) N, compared with 0.39 mm Hg or 5.8 × 10(-3) N (P < .001) for the Greenfield filter. CCE of the absorbable filter was statistically similar to or an improvement on that of the Greenfield stainless steel filter for all clot sizes tested. CCE of the Greenfield filter in this study aligned with data from previous studies. Given the efficacy of the Greenfield filter in attenuating the risk of pulmonary embolism, the current study suggests that the absorbable filter may be a viable candidate for subsequent human testing. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.
Human attention filters for single colors
Sun, Peng; Chubb, Charles; Wright, Charles E.; Sperling, George
2016-01-01
The visual images in the eyes contain much more information than the brain can process. An important selection mechanism is feature-based attention (FBA). FBA is best described by attention filters that specify precisely the extent to which items containing attended features are selectively processed and the extent to which items that do not contain the attended features are attenuated. The centroid-judgment paradigm enables quick, precise measurements of such human perceptual attention filters, analogous to transmission measurements of photographic color filters. Subjects use a mouse to locate the centroid—the center of gravity—of a briefly displayed cloud of dots and receive precise feedback. A subset of dots is distinguished by some characteristic, such as a different color, and subjects judge the centroid of only the distinguished subset (e.g., dots of a particular color). The analysis efficiently determines the precise weight in the judged centroid of dots of every color in the display (i.e., the attention filter for the particular attended color in that context). We report 32 attention filters for single colors. Attention filters that discriminate one saturated hue from among seven other equiluminant distractor hues are extraordinarily selective, achieving attended/unattended weight ratios >20:1. Attention filters for selecting a color that differs in saturation or lightness from distractors are much less selective than attention filters for hue (given equal discriminability of the colors), and their filter selectivities are proportional to the discriminability distance of neighboring colors, whereas in the same range hue attention-filter selectivity is virtually independent of discriminabilty. PMID:27791040
Reduced-Order Kalman Filtering for Processing Relative Measurements
NASA Technical Reports Server (NTRS)
Bayard, David S.
2008-01-01
A study in Kalman-filter theory has led to a method of processing relative measurements to estimate the current state of a physical system, using less computation than has previously been thought necessary. As used here, relative measurements signifies measurements that yield information on the relationship between a later and an earlier state of the system. An important example of relative measurements arises in computer vision: Information on relative motion is extracted by comparing images taken at two different times. Relative measurements do not directly fit into standard Kalman filter theory, in which measurements are restricted to those indicative of only the current state of the system. One approach heretofore followed in utilizing relative measurements in Kalman filtering, denoted state augmentation, involves augmenting the state of the system at the earlier of two time instants and then propagating the state to the later time instant.While state augmentation is conceptually simple, it can also be computationally prohibitive because it doubles the number of states in the Kalman filter. When processing a relative measurement, if one were to follow the state-augmentation approach as practiced heretofore, one would find it necessary to propagate the full augmented state Kalman filter from the earlier time to the later time and then select out the reduced-order components. The main result of the study reported here is proof of a property called reduced-order equivalence (ROE). The main consequence of ROE is that it is not necessary to augment with the full state, but, rather, only the portion of the state that is explicitly used in the partial relative measurement. In other words, it suffices to select the reduced-order components first and then propagate the partial augmented state Kalman filter from the earlier time to the later time; the amount of computation needed to do this can be substantially less than that needed for propagating the full augmented Kalman state filter.
Hosokawa, Kiyohito; Ogawa, Makoto; Iwahashi, Toshihiko; Hashimoto, Michiko; Inohara, Hidenori
2015-11-01
The purpose was to assess whether cervical muscular contraction during phonation influences the period and amplitude perturbation quotients (PPQ and APQ, respectively) of electroglottographic (EGG) signals, and whether high-pass filtering can attenuate these effects. Prospective. We included 19 nondysphonic speakers and 21 patients with muscle tension dysphonia. During the recording of acoustic and EGG signals, each participant was instructed to naturally phonate sustained vowels /i:/ and /a:/ (NP tasks), and additionally, each nondysphonic participant was asked to phonate the same vowels in a nondysphonic voice quality while contracting the cervical muscles (muscular contracted phonation [MCP] tasks). To confirm the contraction, surface and needle electromyography (EMG) was performed. The EGG signals were high-pass filtered at different cutoff frequencies from 0 to 90 Hz and were subsequently analyzed for the PPQ and APQ. Compared with the NP tasks, the MCP tasks enhanced the cervical EMG activities ranging from 0 to more than 1000 Hz, but conferred only low-frequency noise to the EGG signals under 50 Hz and increased the values for EGG-APQ, but not EGG-PPQ. These EGG-APQ values exhibited gradual decreases after high-pass filtering with an increase in the cutoff frequency ranging from 0 to 50 Hz in both groups, followed by plateaus during the MCP tasks in the nondysphonic group. The present results demonstrate that cervical muscular contraction seriously affects the EGG-APQ values for unfiltered EGG signals independent of the EMG activities and that appropriate high-pass filtering over 50 Hz can attenuate these effects. Copyright © 2015 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
Biological UV dosimeters in simulated space irradiation conditions
NASA Astrophysics Data System (ADS)
Rontó, G.; Bérces, A.; Fekete, A.; Kovács, G.; Lammer, H.
For the measurement of the harmful biological effect of solar UV radiation bacteriophage T7 and polycrystalline uracil dosimeters were used. For terrestrial dosimetric purposes bacteriophage T7 has been applied in solution, while uracil in the form of thin layers. For space irradiation dosimetry the uracil, phage T7-DNA and bacteriophage T7 thin layer samples were prepared in vacuum tightly closed sandwich forms covered either by calciumfluoride or quartz windows. The experimental conditions tested correspond to the conditions planned in the EXPOSE facility: the samples were surrounded by nitrogen atmosphere at various humidities, their vacuum stability was tested in the vacuum chamber of the Institute of Space Research,, Graz. All kinds of the thin film samples have been stored in an atmosphere containing Nitrogen and Hidrogen, in quality control no change in the structure of them has been found. To attenuate the high extraterrestrial irradiance neutral filters of 0.5 and 1.0 optical densities have been tested. Irradiation of the samples has been performed with various UV sources: solar simulator, low pressure Mercury lamp, Deuterium lamp. Dose-effect functions have been determined using for the evaluation spectrophotometry in the characteristic UV range, HPLC of photoproducts, PCR of two different primer sequences of phage T7-DNA. Photoproduct formation kinetics was followed by the saturation level of uracil thin layer. Attenuation ability of the neutral filters was controlled with low pressure Mercury lamp by the exposure necessary for saturation of uracil dosimeters. A three and tenfold increase in the exposure was found respectively, while the influence of spectral composition of the irradiation source was tested using Deuterium lamp supplied with Ca F2 and quartz filters respectively. A doubling of the irradiance was necessary for the saturation of uracil with quartz filter.
Matched-filter algorithm for subpixel spectral detection in hyperspectral image data
NASA Astrophysics Data System (ADS)
Borough, Howard C.
1991-11-01
Hyperspectral imagery, spatial imagery with associated wavelength data for every pixel, offers a significant potential for improved detection and identification of certain classes of targets. The ability to make spectral identifications of objects which only partially fill a single pixel (due to range or small size) is of considerable interest. Multiband imagery such as Landsat's 5 and 7 band imagery has demonstrated significant utility in the past. Hyperspectral imaging systems with hundreds of spectral bands offer improved performance. To explore the application of differentpixel spectral detection algorithms a synthesized set of hyperspectral image data (hypercubes) was generated utilizing NASA earth resources and other spectral data. The data was modified using LOWTRAN 7 to model the illumination, atmospheric contributions, attenuations and viewing geometry to represent a nadir view from 10,000 ft. altitude. The base hypercube (HC) represented 16 by 21 spatial pixels with 101 wavelength samples from 0.5 to 2.5 micrometers for each pixel. Insertions were made into the base data to provide random location, random pixel percentage, and random material. Fifteen different hypercubes were generated for blind testing of candidate algorithms. An algorithm utilizing a matched filter in the spectral dimension proved surprisingly good yielding 100% detections for pixels filled greater than 40% with a standard camouflage paint, and a 50% probability of detection for pixels filled 20% with the paint, with no false alarms. The false alarm rate as a function of the number of spectral bands in the range from 101 to 12 bands was measured and found to increase from zero to 50% illustrating the value of a large number of spectral bands. This test was on imagery without system noise; the next step is to incorporate typical system noise sources.
Grundt, Peter; Cao, Jianjing; Platt, Donna M.; Newman, Amy Hauck; Spealman, Roger D.
2010-01-01
Dopamine (DA) D3 and D2 receptor mechanisms are implicated in cocaine's abuse-related behavioral effects, but the relative contribution of the two receptor subtypes is only partially characterized. This study investigated the role of D3 and D2 subtype mechanisms by determining the degree to which the D3-preferring antagonist PG01037 [N-{4-[4-(2,3-dichlorophenyl)-piperazin- 1-yl]-trans-but-2-enyl}-4-pyridine-2-yl-benzamide HCl] and the D2-preferring antagonist L-741626 [3-[4-(4-chlorophenyl)-4- hydroxypiperidin-1-yl]methyl-1H-indole] attenuated several behavioral effects of cocaine in squirrel monkeys. Quantitative observational studies established doses of each antagonist that did not produce untoward effects, which were used in subsequent comparisons. In addition, the ability of the D3-preferring agonist PD128907 [(R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol)] and the D2-preferring agonist sumanirole [(R)-5,6-dihydro-5-(methylamino)-4H- imidazo[4,5,1-ij]quinolin-2(1H)-one(Z)-2-butenedioate] to reproduce cocaine's discriminative stimulus (DS) and priming effects were compared. In monkeys trained to discriminate cocaine from vehicle, both DA antagonists attenuated and both DA agonists partially reproduced cocaine's DS effects. PG01037 also selectively attenuated the cocaine-like DS effects of PD128907, whereas L-741626 attenuated the cocaine-like DS effects of both agonists. In self-administration studies, L-741626 nonselectively reduced cocaine- and food-maintained responding, whereas PG01037 was ineffective against either reinforcer. In studies involving reinstatement of extinguished cocaine seeking, both antagonists attenuated cocaine-induced reinstatement of responding, and both agonists induced at least partial reinstatement of cocaine seeking. L-741626 also attenuated sumanirole-induced, but not PD128907-induced, reinstatement of responding, whereas PG01037 was ineffective against either DA agonist. The results are consistent with a role for D3 and D2 receptor mechanisms in cocaine's DS effects and cocaine-induced reinstatement of drug seeking, but provide no evidence for a major role of D3 receptors in the direct reinforcing effects of cocaine. PMID:20494958
Molecular Filters for Noise Reduction.
Laurenti, Luca; Csikasz-Nagy, Attila; Kwiatkowska, Marta; Cardelli, Luca
2018-06-19
Living systems are inherently stochastic and operate in a noisy environment, yet despite all these uncertainties, they perform their functions in a surprisingly reliable way. The biochemical mechanisms used by natural systems to tolerate and control noise are still not fully understood, and this issue also limits our capacity to engineer reliable, quantitative synthetic biological circuits. We study how representative models of biochemical systems propagate and attenuate noise, accounting for intrinsic as well as extrinsic noise. We investigate three molecular noise-filtering mechanisms, study their noise-reduction capabilities and limitations, and show that nonlinear dynamics such as complex formation are necessary for efficient noise reduction. We further suggest that the derived molecular filters are widespread in gene expression and regulation and, particularly, that microRNAs can serve as such noise filters. To our knowledge, our results provide new insight into how biochemical networks control noise and could be useful to build robust synthetic circuits. Copyright © 2018 Biophysical Society. Published by Elsevier Inc. All rights reserved.
Ultra compact spectrometer using linear variable filters
NASA Astrophysics Data System (ADS)
Dami, M.; De Vidi, R.; Aroldi, G.; Belli, F.; Chicarella, L.; Piegari, A.; Sytchkova, A.; Bulir, J.; Lemarquis, F.; Lequime, M.; Abel Tibérini, L.; Harnisch, B.
2017-11-01
The Linearly Variable Filters (LVF) are complex optical devices that, integrated in a CCD, can realize a "single chip spectrometer". In the framework of an ESA Study, a team of industries and institutes led by SELEX-Galileo explored the design principles and manufacturing techniques, realizing and characterizing LVF samples based both on All-Dielectric (AD) and Metal-Dielectric (MD) Coating Structures in the VNIR and SWIR spectral ranges. In particular the achieved performances on spectral gradient, transmission bandwidth and Spectral Attenuation (SA) are presented and critically discussed. Potential improvements will be highlighted. In addition the results of a feasibility study of a SWIR Linear Variable Filter are presented with the comparison of design prediction and measured performances. Finally criticalities related to the filter-CCD packaging are discussed. The main achievements reached during these activities have been: - to evaluate by design, manufacturing and test of LVF samples the achievable performances compared with target requirements; - to evaluate the reliability of the projects by analyzing their repeatability; - to define suitable measurement methodologies
Morsbach, Fabian; Bickelhaupt, Sebastian; Wanner, Guido A; Krauss, Andreas; Schmidt, Bernhard; Alkadhi, Hatem
2013-07-01
To assess the value of iterative frequency split-normalized (IFS) metal artifact reduction (MAR) for computed tomography (CT) of hip prostheses. This study had institutional review board and local ethics committee approval. First, a hip phantom with steel and titanium prostheses that had inlays of water, fat, and contrast media in the pelvis was used to optimize the IFS algorithm. Second, 41 consecutive patients with hip prostheses who were undergoing CT were included. Data sets were reconstructed with filtered back projection, the IFS algorithm, and a linear interpolation MAR algorithm. Two blinded, independent readers evaluated axial, coronal, and sagittal CT reformations for overall image quality, image quality of pelvic organs, and assessment of pelvic abnormalities. CT attenuation and image noise were measured. Statistical analysis included the Friedman test, Wilcoxon signed-rank test, and Levene test. Ex vivo experiments demonstrated an optimized IFS algorithm by using a threshold of 2200 HU with four iterations for both steel and titanium prostheses. Measurements of CT attenuation of the inlays were significantly (P < .001) more accurate for IFS when compared with filtered back projection. In patients, best overall and pelvic organ image quality was found in all reformations with IFS (P < .001). Pelvic abnormalities in 11 of 41 patients (27%) were diagnosed with significantly (P = .002) higher confidence on the basis of IFS images. CT attenuation of bladder (P < .001) and muscle (P = .043) was significantly less variable with IFS compared with filtered back projection and linear interpolation MAR. In comparison with that of FBP and linear interpolation MAR, noise with IFS was similar close to and far from the prosthesis (P = .295). The IFS algorithm for CT image reconstruction significantly reduces metal artifacts from hip prostheses, improves the reliability of CT number measurements, and improves the confidence for depicting pelvic abnormalities.
Tick Passage Results in Enhanced Attenuation of Babesia bovis
McElwain, Terry F.; Ueti, Massaro W.; Scoles, Glen A.; Reif, Kathryn E.; Lau, Audrey O. T.
2014-01-01
Serial blood passage of virulent Babesia bovis in splenectomized cattle results in attenuated derivatives that do not cause neurologic disease. Tick transmissibility can be lost with attenuation, but when retained, attenuated B. bovis can revert to virulence following tick passage. This study provides data showing that tick passage of the partially attenuated B. bovis T2Bo derivative strain further decreased virulence compared with intravenous inoculation of the same strain in infected animals. Ticks that acquired virulent or attenuated parasites by feeding on infected cattle were transmission fed on naive, splenectomized animals. While there was no significant difference between groups in the number of parasites in the midgut, hemolymph, or eggs of replete female ticks after acquisition feeding, animals infected with the attenuated parasites after tick transmission showed no clinical signs of babesiosis, unlike those receiving intravenous challenge with the same attenuated strain prior to tick passage. Additionally, there were significantly fewer parasites in blood and tissues of animals infected with tick-passaged attenuated parasites. Sequencing analysis of select B. bovis genes before and after tick passage showed significant differences in parasite genotypes in both peripheral blood and cerebral samples. These results provide evidence that not only is tick transmissibility retained by the attenuated T2Bo strain, but also it results in enhanced attenuation and is accompanied by expansion of parasite subpopulations during tick passage that may be associated with the change in disease phenotype. PMID:25114111
NASA Astrophysics Data System (ADS)
Villaverde, Eduardo Lopez; Robert, Sébastien; Prada, Claire
2017-02-01
In the present work, the Total Focusing Method (TFM) is used to image defects in a High Density Polyethylene (HDPE) pipe. The viscoelastic attenuation of this material corrupts the images with a high electronic noise. In order to improve the image quality, the Decomposition of the Time Reversal Operator (DORT) filtering is combined with spatial Walsh-Hadamard coded transmissions before calculating the images. Experiments on a complex HDPE joint demonstrate that this method improves the signal-to-noise ratio by more than 40 dB in comparison with the conventional TFM.
Evaluation of partial beta-adrenoceptor agonist activity.
Lipworth, B J; Grove, A
1997-01-01
A partial beta-adrenoceptor (beta-AR) agonist will exhibit opposite agonist and antagonist activity depending on the prevailing degree of adrenergic tone or the presence of a beta-AR agonist with higher intrinsic activity. In vivo partial beta-AR agonist activity will be evident at rest with low endogenous adrenergic tone, as for example with chronotropicity (beta 1/beta 2), inotropicity (beta 1) or peripheral vasodilatation and finger tremor (beta 2). beta-AR blocking drugs which have partial agonist activity may exhibit a better therapeutic profile when used for hypertension because of maintained cardiac output without increased systemic vascular resistance, along with an improved lipid profile. In the presence of raised endogenous adrenergic tone such as exercise or an exogenous full agonist, beta-AR subtype antagonist activity will become evident in terms of effects on exercise induced heart rate (beta 1) and potassium (beta 2) responses. Reduction of exercise heart rate will occur to a lesser degree in the case of a beta-adrenoceptor blocker with partial beta 1-AR agonist activity compared with a beta-adrenoceptor blocker devoid of partial agonist activity. This may result in reduced therapeutic efficacy in the treatment of angina on effort when using beta-AR blocking drugs with partial beta 1-AR agonist activity. Effects on exercise hyperkalaemia are determined by the balance between beta 2-AR partial agonist activity and endogenous adrenergic activity. For predominantly beta 2-AR agonist such as salmeterol and salbutamol, potentiation of exercise hyperkalaemia occurs. For predominantly beta 2-AR antagonists such as carteolol, either potentiation or attenuation of exercise hyperkalaemia occurs at low and high doses respectively. beta 2-AR partial agonist activity may also be expressed as antagonism in the presence of an exogenous full agonist, as for example attenuation of fenoterol induced responses by salmeterol. Studies are required to investigate whether this phenomenon is relevant in the setting of acute severe asthma.
Ribolsi, Michele; Lin, Ashleigh; Wardenaar, Klaas J; Pontillo, Maria; Mazzone, Luigi; Vicari, Stefano; Armando, Marco
2017-06-01
There is limited research on clinical features related to age of presentation of the Attenuated Psychosis Syndrome in children and adolescents (CAD). Based on findings in CAD with psychosis, we hypothesized that an older age at presentation of Attenuated Psychosis Syndrome would be associated with less severe symptoms and better psychosocial functioning than presentation in childhood or younger adolescence. Ninety-four CAD (age 9-18) meeting Attenuated Psychosis Syndrome criteria participated in the study. The sample was divided and compared according to the age of presentation of Attenuated Psychosis Syndrome (9-14 vs 15-18 years). The predictive value of age of Attenuated Psychosis Syndrome presentation was investigated using receiver operating characteristic (ROC)-curve calculations. The two Attenuated Psychosis Syndrome groups were homogeneous in terms of gender distribution, IQ scores and comorbid diagnoses. Older Attenuated Psychosis Syndrome patients showed better functioning and lower depressive scores. ROC curves revealed that severity of functional impairment was best predicted using an age of presentation cut-off of 14.9 years for social functioning and 15.9 years for role functioning. This study partially confirmed our hypothesis; older age at presentation of Attenuated Psychosis Syndrome was associated with less functional impairment, but age was not associated with psychotic symptoms. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.
Emission computerized axial tomography from multiple gamma-camera views using frequency filtering.
Pelletier, J L; Milan, C; Touzery, C; Coitoux, P; Gailliard, P; Budinger, T F
1980-01-01
Emission computerized axial tomography is achievable in any nuclear medicine department from multiple gamma camera views. Data are collected by rotating the patient in front of the camera. A simple fast algorithm is implemented, known as the convolution technique: first the projection data are Fourier transformed and then an original filter designed for optimizing resolution and noise suppression is applied; finally the inverse transform of the latter operation is back-projected. This program, which can also take into account the attenuation for single photon events, was executed with good results on phantoms and patients. We think that it can be easily implemented for specific diagnostic problems.
O'Driscoll, Nelson J; Vost, Emma; Mann, Erin; Klapstein, Sara; Tordon, Robert; Lukeman, Matthew
2018-06-01
Mercury is a globally distributed, environmental contaminant. Quantifying the retention and loss of mercury is integral for predicting mercury-sensitive ecosystems. There is little information on how dissolved organic carbon (DOC) concentrations and particulates affect mercury photoreaction kinetics in freshwater lakes. To address this knowledge gap, samples were collected from ten lakes in Kejimkujik National Park, Nova Scotia (DOC: 2.6-15.4mg/L). Filtered (0.2μm) and unfiltered samples were analysed for gross photoreduction, gross photooxidation, and net reduction rates of mercury using pseudo first-order curves. Unfiltered samples had higher concentrations (p=0.04) of photoreducible divalent mercury (Hg(II) RED ) (mean of 754±253pg/L) than filtered samples (mean of 482±206pg/L); however, gross photoreduction and photooxidation rate constants were not significantly different in filtered or unfiltered samples in early summer. DOC was not significantly related to gross photoreduction rate constants in filtered (R 2 =0.43; p=0.08) and unfiltered (R 2 =0.02; p=0.71) samples; DOC was also not significantly related to gross photooxidation rate constants in filtered or unfiltered samples. However, DOC was significantly negatively related with Hg(II) RED in unfiltered (R 2 =0.53; p=0.04), but not in filtered samples (R 2 =0.04; p=0.60). These trends indicate that DOC is a factor in determining dissolved mercury photoreduction rates and particles partially control available Hg(II) RED in lake water. This research also demonstrates that within these lakes gross photoreduction and photooxidation processes are close to being in balance. Changes to catchment inputs of particulate matter and DOC may alter mercury retention in these lakes and could partially explain observed increases of mercury accumulation in biota. Copyright © 2017. Published by Elsevier B.V.
Optical attenuation mechanism upgrades, MOBLAS, and TLRS systems
NASA Technical Reports Server (NTRS)
Eichinger, Richard; Johnson, Toni; Malitson, Paul; Oldham, Thomas; Stewart, Loyal
1993-01-01
This poster presentation describes the Optical Attenuation Mechanism (OAM) Upgrades to the MOBLAS and TLRS Crustal Dynamics Satellite Laser Ranging (CDSLR) systems. The upgrades were for the purposes of preparing these systems to laser range to the TOPEX/POSEIDON spacecraft when it will be launched in the summer of 1992. The OAM permits the laser receiver to operate over the expected large signal dynamic range from TOPEX/POSEIDON and it reduces the number of pre- and post-calibrations for each satellite during multi-satellite tracking operations. It further simplifies the calibration bias corrections that had been made due to the pass-to-pass variation of the photomultiplier supply voltage and the transmit filter glass thickness. The upgrade incorporated improvements to the optical alignment capability of each CDSLR system through the addition of a CCD camera into the MOBLAS receive telescope and an alignment telescope onto the TLRS optical table. The OAM is stepper motor and microprocessor based; and the system can be controlled either manually by a control switch panel or computer controlled via an EIA RS-232C serial interface. The OAM has a neutral density (ND) range of 0.0 to 4.0 and the positioning is absolute referenced in steps of 0.1 ND. Both the fixed transmit filter and the daylight filter are solenoid actuated with digital inputs and outputs to and from the OAM microprocessor. During automated operation, the operator has the option to overide the remote control and control the OAM system via a local control switch panel.
Bates, Mary E.; Simmons, James A.
2010-01-01
Big brown bats emit FM biosonar sounds containing two principal harmonics (FM1∼55–22 kHz;FM2∼105–45 kHz). To examine the role of harmonics, they were selectively filtered from stimuli in electronic-echo delay discrimination experiments. Positive stimuli were delayed by 3.16 ms (55 cm simulated target range); negative stimuli were by delayed by 3.96 ms (68 cm). This large 800-μs delay difference (nearly 14 cm) was easily discriminated for echoes containing equal-strength FM1 and FM2. Performance gradually decreased as highpass filters removed progressively larger segments from FM1. For echoes with FM2 alone, performance collapsed to chance, but performance remained good for lowpass echoes containing FM1 alone. Attenuation of FM2 by 3 dB relative to FM1 also decreased performance, but shortening electronic delay of the attenuated FM2 by 48 μs counteracted amplitude-latency trading and restored performance. Bats require the auditory representations of FM1 and FM2 to be in temporal register for high delay acuity. Misalignment of neuronal responses degrades acuity, but outright removal of FM2, leaving only FM1, causes little loss of acuity. Functional asymmetry of harmonics reflects lowpass effects from beaming and atmospheric propagation, which leave FM1 intact. It may cooperate with latency shifts to aid in suppression of clutter. PMID:20707464
Local curvature measurements of a lean, partially premixed swirl-stabilised flame
NASA Astrophysics Data System (ADS)
Bayley, Alan E.; Hardalupas, Yannis; Taylor, Alex M. K. P.
2012-04-01
A swirl-stabilised, lean, partially premixed combustor operating at atmospheric conditions has been used to investigate the local curvature distributions in lifted, stable and thermoacoustically oscillating CH4-air partially premixed flames for bulk cold-flow Reynolds numbers of 15,000 and 23,000. Single-shot OH planar laser-induced fluorescence has been used to capture instantaneous images of these three different flame types. Use of binary thresholding to identify the reactant and product regions in the OH planar laser-induced fluorescence images, in order to extract accurate flame-front locations, is shown to be unsatisfactory for the examined flames. The Canny-Deriche edge detection filter has also been examined and is seen to still leave an unacceptable quantity of artificial flame-fronts. A novel approach has been developed for image analysis where a combination of a non-linear diffusion filter, Sobel gradient and threshold-based curve elimination routines have been used to extract traces of the flame-front to obtain local curvature distributions. A visual comparison of the effectiveness of flame-front identification is made between the novel approach, the threshold binarisation filter and the Canny-Deriche filter. The novel approach appears to most accurately identify the flame-fronts. Example histograms of the curvature for six flame conditions and of the total image area are presented and are found to have a broader range of local flame curvatures for increasing bulk Reynolds numbers. Significantly positive values of mean curvature and marginally positive values of skewness of the histogram have been measured for one lifted flame case, but this is generally accounted for by the effect of flame brush curvature. The mean local flame-front curvature reduces with increasing axial distance from the burner exit plane for all flame types. These changes are more pronounced in the lifted flames but are marginal for the thermoacoustically oscillating flames. It is concluded that additional fuel mixture fraction and velocimetry studies are required to examine whether processes such as the degree of partial-premixedness close to the burner exit plane, the velocity field and the turbulence field have a strong correlation with the curvature characteristics of the investigated flames.
NASA Technical Reports Server (NTRS)
Kilbourne, Caroline A.; Adams, Joseph S.; Arsenovic, Petar; Ayers, Travis; Chiao, Meng P.; DiPirro, Michael J.; Eckart, Megan E.; Fujimoto, Ryuichi; Kazeva, John D.; Kelley, Richard L.;
2016-01-01
The calorimeter array of the JAXA Astro-H (renamed Hitomi) Soft X-ray Spectrometer (SXS) was designed to provide unprecedented spectral resolution of spatially extended cosmic x-ray sources and of all cosmic x-ray sources in the Fe-K band around 6 keV, enabling essential plasma diagnostics. The properties that make the SXS array a powerful x-ray spectrometer also make it sensitive to photons from the entire electromagnetic band, and particles as well. If characterized as a bolometer, it would have a noise equivalent power (NEP) of less than 4x10(exp -18) W/(Hz)0.5(exp 0.5). Thus it was imperative to shield the detector from thermal radiation from the instrument and optical and UV photons from the sky. Additionally, it was necessary to shield the coldest stages of the instrument from the thermal radiation emanating from the warmer stages. Both of these needs are addressed by a series of five thin-film radiation-blocking filters, anchored to the nested temperature stages, that block long-wavelength radiation while minimizing x-ray attenuation. The aperture assembly is a system of barriers, baffles, filter carriers, and filter mounts that supports the filters and inhibits their potential contamination. The three outer filters also have been equipped with thermometers and heaters for decontamination. We present the requirements, design, implementation, and performance of the SXS aperture assembly and blocking filters.
Impact of rare earth element added filters on the X-ray beam spectra: a Monte Carlo approach.
Eskandarlou, Amir; Jafari, Amir Abbas; Mohammadi, Mohammad; Zehtabian, Mehdi; Faghihi, Reza; Shokri, Abbas; Pourolajal, Jalal
2014-01-01
The effectiveness of added filters including conventional and rare earth materials for dental radiography tasks was investigated using a simulation approach. Current study focuses on the combination of a range of various filters to investigate the reduction of radiation absorbed dose and improving the quality of a radiography image. To simulate the X-ray beam spectrum, a MCNP5 code was applied. Relative intensity, beam quality, and mean energy were investigated for a typical dental radiography machine. The impact of different rare-earth materials with different thicknesses and tube voltages on the X-ray spectrum was investigated. For Aluminum as a conventional filter, the modeled X-ray spectra and HVL values were in a good agreement with those reported by IPEM. The results showed that for a 70 kVp voltage, with an increase of the thickness and atomic number of a given added filters, an increase of HVL values were observed. However, with the increase of the attenuator thickness, X-ray beam intensity decreases. For mean energy, different results were observed. It was also found that rare earth made filters reduce high energy X-ray radiation due to k-edge absorption. This leads to an ideal beam for intra-oral radiography tasks. However, as a disadvantage of rare earth added filters, the reduction of the tube output levels should also be considered.
Hammond, Billy R
2015-01-01
To evaluate the effects of filtering short wavelength light on visual performance under intense light conditions among pseudophakic patients previously implanted with a clear intraocular lens (IOL). This was a patient-masked, randomized crossover study conducted at 6 clinical sites in the United States between September 2013 and January 2014. One hundred fifty-four bilaterally pseudophakic patients were recruited. Photostress recovery time and glare disability thresholds were measured with clip-on blue-light-filtering and placebo (clear; no blue-light filtration) glasses worn over patients' habitual correction. Photostress recovery time was quantified as the time necessary to regain sight of a grating target after intense light exposure. Glare disability threshold was assessed as the intensity of a white-light annulus necessary to obscure a central target. The order of filter used and test eye were randomized across patients. Photostress recovery time and glare disability thresholds were significantly improved (both P < 0.0001) when patients used blue-light-filtering glasses compared with clear, nonfiltering glasses. Compared with a nonfiltering placebo, adding a clip-on blue-absorbing filter to the glasses of pseudophakic patients implanted with clear IOLs significantly increased their ability to cope with glare and to recover normal viewing after an intensive photostress. This result implies that IOL designs with blue-light-filtering characteristics may be beneficial under intense light conditions.
NASA Astrophysics Data System (ADS)
Kilbourne, Caroline A.; Adams, Joseph S.; Arsenovic, Petar; Ayers, Travis; Chiao, Meng P.; DiPirro, Michael J.; Eckart, Megan E.; Fujimoto, Ryuichi; Kazeva, John D.; Kripps, Kari L.; Lairson, Bruce M.; Leutenegger, Maurice A.; Lopez, Heidi C.; McCammon, Dan; McGuinness, Daniel S.; Mitsuda, Kazuhisa; Moseley, Samuel J.; Porter, F. Scott; Schweiss, Andrea N.; Takei, Yoh; Thorpe, Rosemary Schmidt; Watanabe, Tomomi; Yamasaki, Noriko Y.; Yoshida, Seiji
2018-01-01
The calorimeter array of the JAXA Astro-H (renamed Hitomi) soft x-ray spectrometer (SXS) was designed to provide unprecedented spectral resolution of spatially extended cosmic x-ray sources and of all cosmic x-ray sources in the Fe-K band around 6 keV. The properties that made the SXS array a powerful x-ray spectrometer also made it sensitive to photons from the entire electromagnetic band as well as particles. If characterized as a bolometer, it would have had a noise equivalent power of <4 × 10 ? 18 W / (Hz)0.5. Thus, it was imperative to shield the detector from thermal radiation from the instrument and optical and UV photons from the sky. In addition, it was necessary to shield the coldest stages of the instrument from the thermal radiation emanating from the warmer stages. These needs were addressed by a series of five thin-film radiation-blocking filters, anchored to the nested temperature stages, that blocked long-wavelength radiation while minimizing x-ray attenuation. The aperture assembly was a system of barriers, baffles, filter carriers, and filter mounts that supported the filters and inhibited their potential contamination. The three outer filters also had been equipped with thermometers and heaters for decontamination. We present the requirements, design, implementation, and performance of the SXS aperture assembly and blocking filters.
Ghumare, Eshwar; Schrooten, Maarten; Vandenberghe, Rik; Dupont, Patrick
2015-08-01
Kalman filter approaches are widely applied to derive time varying effective connectivity from electroencephalographic (EEG) data. For multi-trial data, a classical Kalman filter (CKF) designed for the estimation of single trial data, can be implemented by trial-averaging the data or by averaging single trial estimates. A general linear Kalman filter (GLKF) provides an extension for multi-trial data. In this work, we studied the performance of the different Kalman filtering approaches for different values of signal-to-noise ratio (SNR), number of trials and number of EEG channels. We used a simulated model from which we calculated scalp recordings. From these recordings, we estimated cortical sources. Multivariate autoregressive model parameters and partial directed coherence was calculated for these estimated sources and compared with the ground-truth. The results showed an overall superior performance of GLKF except for low levels of SNR and number of trials.
NASA Astrophysics Data System (ADS)
Nirmalkar, J.; Raman, R. S.
2016-12-01
Ambient PM2.5 samples (N=366) were collected over an ecologically sensitive zone (Van Vihar National Park) in Bhopal, Central India for two years (01 January, 2012 to 31 December, 2013). Samples were collected using three co-located Mini-Vol® samplers on Teflon, Nylon, and Quartz filter substrates. The aerosol was then chemically characterized for water-soluble inorganic ions, elements, and carbon fractions (elemental carbon and organic carbon) using ion chromatography, ED-XRF, and thermal-optical EC/OC analyzer, respectively. The optical attenuation (at 370 nm and 800 nm) of PM2.5 aerosols was also determined by optical transmissometry (OT-21). The application of Positive matrix factorization (PMF) to a combination of PM2.5 mass, its ions, elements, carbon fractions, and optical attenuation and its outcomes will be discussed.
NASA Astrophysics Data System (ADS)
Gao, Long; Yu, Bo-Xiang; Ding, Ya-Yun; Zhou, Li; Wen, Liang-Jian; Xie, Yu-Guang; Wang, Zhi-Gang; Cai, Xiao; Sun, Xi-Lei; Fang, Jian; Xue, Zhen; Zhang, Ai-Wu; Lü, Qi-Wen; Sun, Li-Jun; Ge, Yong-Shuai; Liu, Ying-Biao; Niu, Shun-Li; Hu, Tao; Cao, Jun; Lü, Jun-Guang
2013-07-01
An attenuation length measurement device was constructed using an oscilloscope and LabVIEW for signal acquisition and processing. The performance of the device has been tested in a variety of ways. The test results show that the set-up has a good stability and high precision (sigma/mean reached 0.4 percent). Besides, the accuracy of the measurement system will decrease by about 17 percent if a filter is used. The attenuation length of a gadolinium-loaded liquid scintillator (Gd-LS) was measured as 15.10±0.35 m where Gd-LS was heavily used in the Daya Bay Neutrino Experiment. In addition, one method based on the Beer-Lambert law was proposed to investigate the reliability of the measurement device, the R-square reached 0.9995. Moreover, three purification methods for Linear Alkyl Benzene (LAB) production were compared in the experiment.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fath, L., E-mail: lukas.fath@kit.edu; Hochbruck, M., E-mail: marlis.hochbruck@kit.edu; Singh, C.V., E-mail: chandraveer.singh@utoronto.ca
Classical integration methods for molecular dynamics are inherently limited due to resonance phenomena occurring at certain time-step sizes. The mollified impulse method can partially avoid this problem by using appropriate filters based on averaging or projection techniques. However, existing filters are computationally expensive and tedious in implementation since they require either analytical Hessians or they need to solve nonlinear systems from constraints. In this work we follow a different approach based on corotation for the construction of a new filter for (flexible) biomolecular simulations. The main advantages of the proposed filter are its excellent stability properties and ease of implementationmore » in standard softwares without Hessians or solving constraint systems. By simulating multiple realistic examples such as peptide, protein, ice equilibrium and ice–ice friction, the new filter is shown to speed up the computations of long-range interactions by approximately 20%. The proposed filtered integrators allow step sizes as large as 10 fs while keeping the energy drift less than 1% on a 50 ps simulation.« less
Initial steps of inactivation at the K+ channel selectivity filter
Thomson, Andrew S.; Heer, Florian T.; Smith, Frank J.; Hendron, Eunan; Bernèche, Simon; Rothberg, Brad S.
2014-01-01
K+ efflux through K+ channels can be controlled by C-type inactivation, which is thought to arise from a conformational change near the channel’s selectivity filter. Inactivation is modulated by ion binding near the selectivity filter; however, the molecular forces that initiate inactivation remain unclear. We probe these driving forces by electrophysiology and molecular simulation of MthK, a prototypical K+ channel. Either Mg2+ or Ca2+ can reduce K+ efflux through MthK channels. However, Ca2+, but not Mg2+, can enhance entry to the inactivated state. Molecular simulations illustrate that, in the MthK pore, Ca2+ ions can partially dehydrate, enabling selective accessibility of Ca2+ to a site at the entry to the selectivity filter. Ca2+ binding at the site interacts with K+ ions in the selectivity filter, facilitating a conformational change within the filter and subsequent inactivation. These results support an ionic mechanism that precedes changes in channel conformation to initiate inactivation. PMID:24733889
Layer, R T; Bland, L R; Skolnick, P
1993-10-15
Repeated administration of methamphetamine (METH) results in damage to nigrostriatal dopaminergic neurons. Both competitive N-methyl-D-aspartate (NMDA) receptor antagonists and use-dependent cation channel blockers attenuate METH-induced damage. The objectives of the present study were to examine whether comparable reductions in METH-induced damage could be obtained by compounds acting at strychnine-insensitive glycine receptors on the NMDA receptor complex. Four injections of METH (5 mg/kg i.p.) resulted in a approximately 70.9% depletion of striatal dopamine (DA) and approximately 62.7% depletion of dihydroxyphenylacetic acid (DOPAC) content, respectively. A significant protection against METH-induced DA and DOPAC depletion was afforded by the use-dependent channel blocker, MK-801. The competitive glycine antagonist 7-chlorokynurenic acid (7-Cl-KA), the low efficacy glycine partial agonist (+)-3-amino-1-hydroxy-2-pyrrolidone ((+)-HA-966), and the high efficacy partial glycine agonist 1-aminocyclopropane-carboxylic acid (ACPC) were ineffective against METH-induced toxicity despite their abilities to attenuate glutamate-induced neurotoxicity under both in vivo and in vitro conditions. These results indicate that glycinergic ligands do not possess the same broad neuroprotective spectrum as other classes of NMDA antagonists.
Characterization of Mid-Infrared Single Mode Fibers as Modal Filters
NASA Technical Reports Server (NTRS)
Ksendzov, A.; Lay, O.; Martin, S.; Sanghera, J. S.; Busse, L. E.; Kim, W. H.; Pureza, P. C.; Nguyen, V. Q.; Aggarwal, I. D.
2007-01-01
We present a technique for measuring the modal filtering ability of single mode fibers. The ideal modal filter rejects all input field components that have no overlap with the fundamental mode of the filter and does not attenuate the fundamental mode. We define the quality of a nonideal modal filter Q(sub f) as the ratio of transmittance for the fundamental mode to the transmittance for an input field that has no overlap with the fundamental mode. We demonstrate the technique on a 20 cm long mid-infrared fiber that was produced by the U.S. Naval Research Laboratory. The filter quality Q(sub f) for this fiber at 10.5 micron wavelength is 1000 +/- 300. The absorption and scattering losses in the fundamental mode are approximately 8 dB/m. The total transmittance for the fundamental mode, including Fresnel reflections, is 0.428 +/- 0.002. The application of interest is the search for extrasolar Earthlike planets using nulling interferometry. It requires high rejection ratios to suppress the light of a bright star, so that the faint planet becomes visible. The use of modal filters increases the rejection ratio (or, equivalently, relaxes requirements on the wavefront quality) by reducing the sensitivity to small wavefront errors. We show theoretically that, exclusive of coupling losses, the use of a modal filter leads to the improvement of the rejection ratio in a two-beam interferometer by a factor of Q(sub f).
NASA Technical Reports Server (NTRS)
Tian, Lin; Heymsfield, G. M.; Srivastava, R. C.; O'C.Starr, D. (Technical Monitor)
2001-01-01
Observations by the airborne X-band Doppler radar (EDOP) and the NCAR S-band polarimetric (S-Pol) radar from two field experiments are used to evaluate the surface reference technique (SRT) for measuring the path integrated attenuation (PIA) and to study attenuation in deep convective storms. The EDOP, flying at an altitude of 20 km, uses a nadir beam and a forward pointing beam. It is found that over land, the surface scattering cross-section is highly variable at nadir incidence but relatively stable at forward incidence. It is concluded that measurement by the forward beam provides a viable technique for measuring PIA using the SRT. Vertical profiles of peak attenuation coefficient are derived in two deep convective storms by the dual-wavelength method. Using the measured Doppler velocity, the reflectivities at the two wavelengths, the differential reflectivity and the estimated attenuation coefficients, it is shown that: supercooled drops and (dry) ice particles probably co-existed above the melting level in regions of updraft, that water-coated partially melted ice particles probably contributed to high attenuation below the melting level.
Albers, Christian Nyrop; Ellegaard-Jensen, Lea; Hansen, Lars Hestbjerg; Sørensen, Sebastian R
2018-02-01
Ammonium oxidation to nitrite and then to nitrate (nitrification) is a key process in many waterworks treating groundwater to make it potable. In rapid sand filters, nitrifying microbial communities may evolve naturally from groundwater bacteria entering the filters. However, in new filters this may take several months, and in some cases the nitrification process is never sufficiently rapid to be efficient or is only performed partially, with nitrite as an undesired end product. The present study reports the first successful priming of nitrification in a rapid sand filter treating groundwater. It is shown that nitrifying communities could be enriched by microbiomes from well-functioning rapid sand filters in waterworks and that the enriched nitrifying consortium could be used to inoculate fresh filters, significantly shortening the time taken for the nitrification process to start. The key nitrifiers in the enrichment were different from those in the well-functioning filter, but similar to those that initiated the nitrification process in fresh filters without inoculation. Whether or not the nitrification was primed with the enriched nitrifying consortium, the bacteria performing the nitrification process during start-up appeared to be slowly outcompeted by Nitrospira, the dominant nitrifying bacterium in well-functioning rapid sand filters. Copyright © 2017 Elsevier Ltd. All rights reserved.
A high-temperature fiber sensor using a low cost interrogation scheme.
Barrera, David; Sales, Salvador
2013-09-04
Regenerated Fibre Bragg Gratings have the potential for high-temperature monitoring. In this paper, the inscription of Fibre Bragg Gratings (FBGs) and the later regeneration process to obtain Regenerated Fiber Bragg Gratings (RFBGs) in high-birefringence optical fiber is reported. The obtained RFBGs show two Bragg resonances corresponding to the slow and fast axis that are characterized in temperature terms. As the temperature increases the separation between the two Bragg resonances is reduced, which can be used for low cost interrogation. The proposed interrogation setup is based in the use of optical filters in order to convert the wavelength shift of each of the Bragg resonances into optical power changes. The design of the optical filters is also studied in this article. In first place, the ideal filter is calculated using a recursive method and defining the boundary conditions. This ideal filter linearizes the output of the interrogation setup but is limited by the large wavelength shift of the RFBG with temperature and the maximum attenuation. The response of modal interferometers as optical filters is also analyzed. They can be easily tuned shifting the optical spectrum. The output of the proposed interrogation scheme is simulated in these conditions improving the sensitivity.
A High-Temperature Fiber Sensor Using a Low Cost Interrogation Scheme
Barrera, David; Sales, Salvador
2013-01-01
Regenerated Fibre Bragg Gratings have the potential for high-temperature monitoring. In this paper, the inscription of Fibre Bragg Gratings (FBGs) and the later regeneration process to obtain Regenerated Fiber Bragg Gratings (RFBGs) in high-birefringence optical fiber is reported. The obtained RFBGs show two Bragg resonances corresponding to the slow and fast axis that are characterized in temperature terms. As the temperature increases the separation between the two Bragg resonances is reduced, which can be used for low cost interrogation. The proposed interrogation setup is based in the use of optical filters in order to convert the wavelength shift of each of the Bragg resonances into optical power changes. The design of the optical filters is also studied in this article. In first place, the ideal filter is calculated using a recursive method and defining the boundary conditions. This ideal filter linearizes the output of the interrogation setup but is limited by the large wavelength shift of the RFBG with temperature and the maximum attenuation. The response of modal interferometers as optical filters is also analyzed. They can be easily tuned shifting the optical spectrum. The output of the proposed interrogation scheme is simulated in these conditions improving the sensitivity. PMID:24008282
Initial Alignment of Large Azimuth Misalignment Angles in SINS Based on Adaptive UPF
Sun, Jin; Xu, Xiao-Su; Liu, Yi-Ting; Zhang, Tao; Li, Yao
2015-01-01
The case of large azimuth misalignment angles in a strapdown inertial navigation system (SINS) is analyzed, and a method of using the adaptive UPF for the initial alignment is proposed. The filter is based on the idea of a strong tracking filter; through the introduction of the attenuation memory factor to effectively enhance the corrections of the current information residual error on the system, it reduces the influence on the system due to the system simplification, and the uncertainty of noise statistical properties to a certain extent; meanwhile, the UPF particle degradation phenomenon is better overcome. Finally, two kinds of non-linear filters, UPF and adaptive UPF, are adopted in the initial alignment of large azimuth misalignment angles in SINS, and the filtering effects of the two kinds of nonlinear filter on the initial alignment were compared by simulation and turntable experiments. The simulation and turntable experiment results show that the speed and precision of the initial alignment using adaptive UPF for a large azimuth misalignment angle in SINS under the circumstance that the statistical properties of the system noise are certain or not have been improved to some extent. PMID:26334277
Strong Lg-wave attenuation in the Middle East continental collision orogenic belt
NASA Astrophysics Data System (ADS)
Zhao, Lian-Feng; Xie, Xiao-Bi
2016-04-01
Using Lg-wave Q tomography, we construct a broadband crustal attenuation model for the Middle East. The QLg images reveal a relationship between attenuation and geological structures. Strong attenuation is found in the continental collision orogenic belt that extends from the Turkish and Iranian plateau to the Pamir plateau. We investigate the frequency dependence of QLg in different geologic formations. The results illustrate that QLg values generally increase with increasing frequency but exhibit complex relationships both with frequency and between regions. An average QLg value between 0.2 and 2.0 Hz, QLg (0.2-2.0 Hz), may be a critical index for crustal attenuation and is used to infer the regional geology. Low-QLg anomalies are present in the eastern Turkish plateau and correlate well with low Pn-velocities and Cenozoic volcanic activity, thus indicating possible partial melting within the crust in this region. Very strong attenuation is also observed in central Iran, the Afghanistan block, and the southern Caspian Sea. This in line with the previously observed high crustal temperature, high-conductivity layers, and thick marine sediments in these areas, suggests the high Lg attenuation is caused by abnormally high tectonic and thermal activities.
Gas stream clean-up filter and method for forming same
Mei, Joseph S.; DeVault, James; Halow, John S.
1993-01-01
A gas cleaning filter is formed in-situ within a vessel containing a fluidizable bed of granular material of a relatively large size fraction. A filter membrane provided by a porous metal or ceramic body or such a body supported a perforated screen on one side thereof is coated in-situ with a layer of the granular material from the fluidized bed by serially passing a bed-fluidizing gas stream through the bed of granular material and the membrane. The layer of granular material provides the filtering medium for the combined membrane-granular layer filter. The filter is not blinded by the granular material and provides for the removal of virtually all of the particulates from a process gas stream. The granular material can be at least partially provided by a material capable of chemically reacting with and removing sulfur compounds from the process gas stream. Low level radioactive waste containing organic material may be incinerated in a fluidized bed in communication with the described filter for removing particulates from the gaseous combustion products.
Carbonaro, Theresa M.; Eshleman, Amy J.; Forster, Michael J.; Cheng, Kejun; Rice, Kenner C.; Gatch, Michael B.
2014-01-01
Rationale: Serotonin 5-HT2A and 5-HT2C receptors are thought to be the primary pharmacological mechanisms for serotonin-mediated hallucinogenic drugs, but recently there has been interest in metabotropic glutamate (mGluR2) receptors as contributors to the mechanism of hallucinogens. Objective: The present study assesses the role of these 5-HT and glutamate receptors as molecular targets for two tryptamine hallucinogens, N,N-dimethyltryptamine (DMT) and N,N-diisopropyltryptamine (DiPT). Methods: Drug discrimination, head twitch and radioligand binding assays were used. A 5-HT2AR inverse agonist (MDL100907), 5-HT2CR antagonist (SB242084) and mGluR2/3 agonist (LY379268) were tested for their ability to attenuate the discriminative stimulus effects of DMT and DiPT; an mGluR2/3 antagonist (LY341495) was tested for potentiation. MDL100907 was used to attenuate head twitches induced by DMT and DiPT. Radioligand binding studies and inosital-1-phosphate (IP-1) accumulation were performed at the 5-HT2CR for DiPT. Results: MDL100907 fully blocked the discriminative stimulus effects of DMT, but only partially blocked DiPT. SB242084 partially attenuated the discriminative stimulus effects of DiPT, but produced minimal attenuation of DMT’s effects. LY379268 produced potent, but only partial blockade of the discriminative stimulus effects of DMT. LY341495 facilitated DMT- and DiPT-like effects. Both compounds elicited head twitches (DiPT>DMT) which were blocked by MDL1000907. DiPT was a low potency full agonist at 5-HT2CR in vitro. Conclusions: The 5-HT2AR likely plays a major role in mediating the effects of both compounds. 5-HT2C and mGluR2 receptors likely modulate the discriminative stimulus effects of both compounds to some degree. PMID:24985890
Carbonaro, Theresa M; Eshleman, Amy J; Forster, Michael J; Cheng, Kejun; Rice, Kenner C; Gatch, Michael B
2015-01-01
Serotonin 5-HT2A and 5-HT2C receptors are thought to be the primary pharmacological mechanisms for serotonin-mediated hallucinogenic drugs, but recently there has been interest in metabotropic glutamate (mGluR2) receptors as contributors to the mechanism of hallucinogens. The present study assesses the role of these 5-HT and glutamate receptors as molecular targets for two tryptamine hallucinogens, N,N-dimethyltryptamine (DMT) and N,N-diisopropyltryptamine (DiPT). Drug discrimination, head twitch, and radioligand binding assays were used. A 5-HT2AR inverse agonist (MDL100907), 5-HT2CR antagonist (SB242084), and mGluR2/3 agonist (LY379268) were tested for their ability to attenuate the discriminative stimulus effects of DMT and DiPT; an mGluR2/3 antagonist (LY341495) was tested for potentiation. MDL100907 was used to attenuate head twitches induced by DMT and DiPT. Radioligand binding studies and inosital-1-phosphate (IP-1) accumulation were performed at the 5-HT2CR for DiPT. MDL100907 fully blocked the discriminative stimulus effects of DMT, but only partially blocked DiPT. SB242084 partially attenuated the discriminative stimulus effects of DiPT, but produced minimal attenuation of DMT's effects. LY379268 produced potent, but only partial blockade of the discriminative stimulus effects of DMT. LY341495 facilitated DMT- and DiPT-like effects. Both compounds elicited head twitches (DiPT>DMT) which were blocked by MDL1000907. DiPT was a low-potency full agonist at 5-HT2CR in vitro. The 5-HT2AR likely plays a major role in mediating the effects of both compounds. 5-HT2C and mGluR2 receptors likely modulate the discriminative stimulus effects of both compounds to some degree.
Frequency-selective quantitation of short-echo time 1H magnetic resonance spectra
NASA Astrophysics Data System (ADS)
Poullet, Jean-Baptiste; Sima, Diana M.; Van Huffel, Sabine; Van Hecke, Paul
2007-06-01
Accurate and efficient filtering techniques are required to suppress large nuisance components present in short-echo time magnetic resonance (MR) spectra. This paper discusses two powerful filtering techniques used in long-echo time MR spectral quantitation, the maximum-phase FIR filter (MP-FIR) and the Hankel-Lanczos Singular Value Decomposition with Partial ReOrthogonalization (HLSVD-PRO), and shows that they can be applied to their more complex short-echo time spectral counterparts. Both filters are validated and compared through extensive simulations. Their properties are discussed. In particular, the capability of MP-FIR for dealing with macromolecular components is emphasized. Although this property does not make a large difference for long-echo time MR spectra, it can be important when quantifying short-echo time spectra.
NASA Astrophysics Data System (ADS)
Zhou, Meiling; Singh, Alok Kumar; Pedrini, Giancarlo; Osten, Wolfgang; Min, Junwei; Yao, Baoli
2018-03-01
We present a tunable output-frequency filter (TOF) algorithm to reconstruct the object from noisy experimental data under low-power partially coherent illumination, such as LED, when imaging through scattering media. In the iterative algorithm, we employ Gaussian functions with different filter windows at different stages of iteration process to reduce corruption from experimental noise to search for a global minimum in the reconstruction. In comparison with the conventional iterative phase retrieval algorithm, we demonstrate that the proposed TOF algorithm achieves consistent and reliable reconstruction in the presence of experimental noise. Moreover, the spatial resolution and distinctive features are retained in the reconstruction since the filter is applied only to the region outside the object. The feasibility of the proposed method is proved by experimental results.
Experimental evidence of the spatial coherence moiré and the filtering of classes of radiator pairs.
Castaneda, Roman; Usuga-Castaneda, Mario; Herrera-Ramírez, Jorge
2007-08-01
Evidence of the physical existence of the spatial coherence moiré is obtained by confronting numerical results with experimental results of spatially partial interference. Although it was performed for two particular cases, the results reveal a general behavior of the optical fields in any state of spatial coherence. Moreover, the study of the spatial coherence moiré deals with a new type of filtering, named filtering of classes of radiator pairs, which allows changing the power spectrum at the observation plane by modulating the complex degree of spatial coherence, without altering the power distribution at the aperture plane or introducing conventional spatial filters. This new procedure can optimize some technological applications of actual interest, as the beam shaping for instance.
On VLSI Design of Rank-Order Filtering using DCRAM Architecture
Lin, Meng-Chun; Dung, Lan-Rong
2009-01-01
This paper addresses on VLSI design of rank-order filtering (ROF) with a maskable memory for real-time speech and image processing applications. Based on a generic bit-sliced ROF algorithm, the proposed design uses a special-defined memory, called the dual-cell random-access memory (DCRAM), to realize major operations of ROF: threshold decomposition and polarization. Using the memory-oriented architecture, the proposed ROF processor can benefit from high flexibility, low cost and high speed. The DCRAM can perform the bit-sliced read, partial write, and pipelined processing. The bit-sliced read and partial write are driven by maskable registers. With recursive execution of the bit-slicing read and partial write, the DCRAM can effectively realize ROF in terms of cost and speed. The proposed design has been implemented using TSMC 0.18 μm 1P6M technology. As shown in the result of physical implementation, the core size is 356.1 × 427.7μm2 and the VLSI implementation of ROF can operate at 256 MHz for 1.8V supply. PMID:19865599
Karr, Jr., Clarence
1977-04-19
An improved coal liquefaction process is provided which enables conversion of a coal-oil slurry to a synthetic crude refinable to produce larger yields of gasoline and diesel oil. The process is characterized by a two-step operation applied to the slurry prior to catalytic desulfurization and hydrogenation in which the slurry undergoes partial hydrogenation to crack and hydrogenate asphaltenes and the partially hydrogenated slurry is filtered to remove minerals prior to subsequent catalytic hydrogenation.
Space Shuttle propulsion parameter estimation using optimal estimation techniques
NASA Technical Reports Server (NTRS)
1983-01-01
This fourth monthly progress report again contains corrections and additions to the previously submitted reports. The additions include a simplified SRB model that is directly incorporated into the estimation algorithm and provides the required partial derivatives. The resulting partial derivatives are analytical rather than numerical as would be the case using the SOBER routines. The filter and smoother routine developments have continued. These routines are being checked out.
Fan filters, the 3-D Radon transform, and image sequence analysis.
Marzetta, T L
1994-01-01
This paper develops a theory for the application of fan filters to moving objects. In contrast to previous treatments of the subject based on the 3-D Fourier transform, simplicity and insight are achieved by using the 3-D Radon transform. With this point of view, the Radon transform decomposes the image sequence into a set of plane waves that are parameterized by a two-component slowness vector. Fan filtering is equivalent to a multiplication in the Radon transform domain by a slowness response function, followed by an inverse Radon transform. The plane wave representation of a moving object involves only a restricted set of slownesses such that the inner product of the plane wave slowness vector and the moving object velocity vector is equal to one. All of the complexity in the application of fan filters to image sequences results from the velocity-slowness mapping not being one-to-one; therefore, the filter response cannot be independently specified at all velocities. A key contribution of this paper is to elucidate both the power and the limitations of fan filtering in this new application. A potential application of 3-D fan filters is in the detection of moving targets in clutter and noise. For example, an appropriately designed fan filter can reject perfectly all moving objects whose speed, irrespective of heading, is less than a specified cut-off speed, with only minor attenuation of significantly faster objects. A simple geometric construction determines the response of the filter for speeds greater than the cut-off speed.
Becerra-Luna, Brayans; Martínez-Memije, Raúl; Cartas-Rosado, Raúl; Infante-Vázquez, Oscar
To improve the identification of peaks and feet in photoplethysmographic (PPG) pulses deformed by myokinetic noise, through the implementation of a modified fingertip and applying adaptive filtering. PPG signals were recordedfrom 10 healthy volunteers using two photoplethysmography systems placed on the index finger of each hand. Recordings lasted three minutes andwere done as follows: during the first minute, both handswere at rest, and for the lasting two minutes only the left hand was allowed to make quasi-periodicmovementsin order to add myokinetic noise. Two methodologies were employed to process the signals off-line. One consisted on using an adaptive filter based onthe Least Mean Square (LMS) algorithm, and the other includeda preprocessing stage in addition to the same LMS filter. Both filtering methods were compared and the one with the lowest error was chosen to assess the improvement in the identification of peaks and feet from PPG pulses. Average percentage errorsobtained wereof 22.94% with the first filtering methodology, and 3.72% withthe second one. On identifying peaks and feet from PPG pulsesbefore filtering, error percentages obtained were of 24.26% and 48.39%, respectively, and once filtered error percentageslowered to 2.02% for peaks and 3.77% for feet. The attenuation of myokinetic noise in PPG pulses through LMS filtering, plusa preprocessing stage, allows increasingthe effectiveness onthe identification of peaks and feet from PPG pulses, which are of great importance for medical assessment. Copyright © 2016 Instituto Nacional de Cardiología Ignacio Chávez. Publicado por Masson Doyma México S.A. All rights reserved.
Strain-dependent partial slip on rock fractures under seismic-frequency torsion
NASA Astrophysics Data System (ADS)
Saltiel, Seth; Bonner, Brian P.; Ajo-Franklin, Jonathan B.
2017-05-01
Measurements of nonlinear modulus and attenuation of fractures provide the opportunity to probe their mechanical state. We have adapted a low-frequency torsional apparatus to explore the seismic signature of fractures under low normal stress, simulating low effective stress environments such as shallow or high pore pressure reservoirs. We report strain-dependent modulus and attenuation for fractured samples of Duperow dolomite (a carbon sequestration target reservoir in Montana), Blue Canyon Dome rhyolite (a geothermal analog reservoir in New Mexico), and Montello granite (a deep basement disposal analog from Wisconsin). We use a simple single effective asperity partial slip model to fit our measured stress-strain curves and solve for the friction coefficient, contact radius, and full slip condition. These observations have the potential to develop into new field techniques for measuring differences in frictional properties during reservoir engineering manipulations and estimate the stress conditions where reservoir fractures and faults begin to fully slip.
Yen, T-Y; Li, K-P; Ou, S-C; Shien, J-H; Lu, H-M; Chang, P-C
2015-01-01
Muscovy duck parvovirus (MDPV) infection is a highly contagious and fatal disease of Muscovy ducklings. The infectious clone methodology is a valuable tool to study the pathogenic mechanisms of viruses, but no infectious clone of MDPV is yet available. In this study, a plasmid clone containing the full-length genome of MDPV was constructed using the TA cloning methodology. This MDPV clone was found to be infectious after transfection of primary Muscovy duck embryo fibroblast cells and passage in embryonated Muscovy duck eggs. Site-directed mutagenesis showed that the K75N mutation in the VP1 protein of MDPV resulted in the partial attenuation of the virus. The availability of an MDPV infectious clone can facilitate investigation of the pathogenic mechanisms of MDPV and development of vaccines against diseases caused by MDPV.
Chen, Wentao; Zhang, Weidong
2009-10-01
In an optical disk drive servo system, to attenuate the external periodic disturbances induced by inevitable disk eccentricity, repetitive control has been used successfully. The performance of a repetitive controller greatly depends on the bandwidth of the low-pass filter included in the repetitive controller. However, owing to the plant uncertainty and system stability, it is difficult to maximize the bandwidth of the low-pass filter. In this paper, we propose an optimality based repetitive controller design method for the track-following servo system with norm-bounded uncertainties. By embedding a lead compensator in the repetitive controller, both the system gain at periodic signal's harmonics and the bandwidth of the low-pass filter are greatly increased. The optimal values of the repetitive controller's parameters are obtained by solving two optimization problems. Simulation and experimental results are provided to illustrate the effectiveness of the proposed method.
Integrable microwave filter based on a photonic crystal delay line.
Sancho, Juan; Bourderionnet, Jerome; Lloret, Juan; Combrié, Sylvain; Gasulla, Ivana; Xavier, Stephane; Sales, Salvador; Colman, Pierre; Lehoucq, Gaelle; Dolfi, Daniel; Capmany, José; De Rossi, Alfredo
2012-01-01
The availability of a tunable delay line with a chip-size footprint is a crucial step towards the full implementation of integrated microwave photonic signal processors. Achieving a large and tunable group delay on a millimetre-sized chip is not trivial. Slow light concepts are an appropriate solution, if propagation losses are kept acceptable. Here we use a low-loss 1.5 mm-long photonic crystal waveguide to demonstrate both notch and band-pass microwave filters that can be tuned over the 0-50-GHz spectral band. The waveguide is capable of generating a controllable delay with limited signal attenuation (total insertion loss below 10 dB when the delay is below 70 ps) and degradation. Owing to the very small footprint of the delay line, a fully integrated device is feasible, also featuring more complex and elaborate filter functions.
Building and Testing a Superconductivity Measurement Platform for a Helium Cryostat
NASA Astrophysics Data System (ADS)
Rose, Heath; Ostrander, Joshua; Wu, Jim; Ramos, Roberto
2013-03-01
Superconductivity experiments using Josephson junctions are an excellent environment to study quantum mechanics and materials science. A standard electrical transport technique uses filtered four wire measurement of these superconducting devices. We report our experience as undergraduates in a liberal arts college in building and testing an experimental platform anchored on the cold-finger of a helium cryostat and designed for performing differential conductance measurements in Josephson junctions. To filter out RF, we design, build and test cryogenic filters using ceramic capacitors and inductors and thermocoax cables. We also use fixed attenuators for thermal anchoring and use miniature connectors to connect wires and coax to a sample box. We report on progress in our diagnostic measurements as well as low-temperature tunneling experiments to probe the structure of the energy gap in both single- and multi-gapped superconductors. We acknowledge the support of the National Science Foundation through NSF Grant DMR-1206561.
Two-Dimensional Planar Lightwave Circuit Integrated Spatial Filter Array and Method of Use Thereof
NASA Technical Reports Server (NTRS)
Dimov, Fedor (Inventor); Ai, Jun (Inventor)
2015-01-01
A large coherent two-dimensional (2D) spatial filter array (SFA), 30 by 30 or larger, is produced by coupling a 2D planar lightwave circuit (PLC) array with a pair of lenslet arrays at the input and output side. The 2D PLC array is produced by stacking a plurality of chips, each chip with a plural number of straight PLC waveguides. A pupil array is coated onto the focal plane of the lenslet array. The PLC waveguides are produced by deposition of a plural number of silica layers on the silicon wafer, followed by photolithography and reactive ion etching (RIE) processes. A plural number of mode filters are included in the silica-on-silicon waveguide such that the PLC waveguide is transparent to the fundamental mode but higher order modes are attenuated by 40 dB or more.
Broadly tunable thin-film intereference coatings: active thin films for telecom applications
NASA Astrophysics Data System (ADS)
Domash, Lawrence H.; Ma, Eugene Y.; Lourie, Mark T.; Sharfin, Wayne F.; Wagner, Matthias
2003-06-01
Thin film interference coatings (TFIC) are the most widely used optical technology for telecom filtering, but until recently no tunable versions have been known except for mechanically rotated filters. We describe a new approach to broadly tunable TFIC components based on the thermo-optic properties of semiconductor thin films with large thermo-optic coefficients 3.6X10[-4]/K. The technology is based on amorphous silicon thin films deposited by plasma-enhanced chemical vapor deposition (PECVD), a process adapted for telecom applications from its origins in the flat-panel display and solar cell industries. Unlike MEMS devices, tunable TFIC can be designed as sophisticated multi-cavity, multi-layer optical designs. Applications include flat-top passband filters for add-drop multiplexing, tunable dispersion compensators, tunable gain equalizers and variable optical attenuators. Extremely compact tunable devices may be integrated into modules such as optical channel monitors, tunable lasers, gain-equalized amplifiers, and tunable detectors.
Ultrasonic investigation of the superconducting properties of the Nb-Mo system
NASA Technical Reports Server (NTRS)
Lacy, L. L.
1972-01-01
The superconducting properties of single crystals of Nb and two alloys of Nb with Mo were investigated by ultrasonic techniques. The results of measurements of the ultrasonic attenuation and velocities as a function of temperature, Mo composition, crystallographic direction, and ultrasonic frequency are reported. The attenuation and small velocity changes associated with the superconductivity of the samples are shown to be dependent on the sample resistivity ratio which varied from 4.3 for Nb-9% Mo to 6500 for pure Nb. The ultrasonic attenuation data are analyzed in terms of the superconducting energy gap term of the BCS theory. A new model is proposed for the analysis of ultrasonic attenuation in pure superconductors with two partially decoupled energy bands. To analyze the attenuation in pure superconducting Nb, the existence of two energy gaps was assumed to be associated with the two partially decoupled energy bands. One of the gaps was found to have the normal BCS value of 3.4 and the other gap was found to have the anomalously large value of 10. No experimental evidence was found to suggest that the second energy gap had a different transition temperature. The interpretation of the results for the Nb-Mo alloys is shown to be complicated by the possible existence of a second superconducting phase in Nb-Mo alloys with a transition temperature of 0.35 of the transition temperature of the first phase. The elastic constants of Nb and Nb-Mo alloys are shown to be approximately independent of Mo composition to nine atomic percent Mo. These results do not agree with the current microscopic theory of transition temperature for the transition elements.
Onishi, Hideo; Motomura, Nobutoku; Takahashi, Masaaki; Yanagisawa, Masamichi; Ogawa, Koichi
2010-03-01
Degradation of SPECT images results from various physical factors. The primary aim of this study was the development of a digital phantom for use in the characterization of factors that contribute to image degradation in clinical SPECT studies. A 3-dimensional mathematic cylinder (3D-MAC) phantom was devised and developed. The phantom (200 mm in diameter and 200 mm long) comprised 3 imbedded stacks of five 30-mm-long cylinders (diameters, 4, 10, 20, 40, and 60 mm). In simulations, the 3 stacks and the background were assigned radioisotope concentrations and attenuation coefficients. SPECT projection datasets that included Compton scattering effects, photoelectric effects, and gamma-camera models were generated using the electron gamma-shower Monte Carlo simulation program. Collimator parameters, detector resolution, total photons acquired, number of projections acquired, and radius of rotation were varied in simulations. The projection data were formatted in Digital Imaging and Communications in Medicine (DICOM) and imported to and reconstructed using commercial reconstruction software on clinical SPECT workstations. Using the 3D-MAC phantom, we validated that contrast depended on size of region of interest (ROI) and was overestimated when the ROI was small. The low-energy general-purpose collimator caused a greater partial-volume effect than did the low-energy high-resolution collimator, and contrast in the cold region was higher using the filtered backprojection algorithm than using the ordered-subset expectation maximization algorithm in the SPECT images. We used imported DICOM projection data and reconstructed these data using vendor software; in addition, we validated reconstructed images. The devised and developed 3D-MAC SPECT phantom is useful for the characterization of various physical factors, contrasts, partial-volume effects, reconstruction algorithms, and such, that contribute to image degradation in clinical SPECT studies.
An electronically tunable, first-order Fabry-Perot infrared filter
NASA Astrophysics Data System (ADS)
Knudtson, J. T.; Levy, D. S.; Herr, K. C.
1995-04-01
A tunable infrared filter capable of scanning from 8.2 to 12.8 micrometers has been designed, constructed and tested. It is a first order Fabry Perot interferometer with piezoelectrically driven cavity spacing. Multilayer dielectric coatings for the partially transmitting mirrors were designed to minimize the wavelength dependent phase change produced by reflection. The transmission bandwidth ranged from 2.8 to 4.0% across the tuning range. Continuous scanning at 20 Hz rates was demonstrated.
Hill, Terence E.; Smith, Jennifer K.; Zhang, Lihong; Juelich, Terry L.; Gong, Bin; Slack, Olga A. L.; Ly, Hoai J.; Lokugamage, Nandadeva; Freiberg, Alexander N.
2015-01-01
ABSTRACT Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to Africa and characterized by a high rate of abortion in ruminants and hemorrhagic fever, encephalitis, or blindness in humans. RVF is caused by Rift Valley fever virus (RVFV; family Bunyaviridae, genus Phlebovirus), which has a tripartite negative-stranded RNA genome (consisting of the S, M, and L segments). Further spread of RVF into countries where the disease is not endemic may affect the economy and public health, and vaccination is an effective approach to prevent the spread of RVFV. A live-attenuated MP-12 vaccine is one of the best-characterized RVF vaccines for safety and efficacy and is currently conditionally licensed for use for veterinary purposes in the United States. Meanwhile, as of 2015, no other RVF vaccine has been conditionally or fully licensed for use in the United States. The MP-12 strain is derived from wild-type pathogenic strain ZH548, and its genome encodes 23 mutations in the three genome segments. However, the mechanism of MP-12 attenuation remains unknown. We characterized the attenuation of wild-type pathogenic strain ZH501 carrying a mutation(s) of the MP-12 S, M, or L segment in a mouse model. Our results indicated that MP-12 is attenuated by the mutations in the S, M, and L segments, while the mutations in the M and L segments confer stronger attenuation than those in the S segment. We identified a combination of 3 amino acid changes, Y259H (Gn), R1182G (Gc), and R1029K (L), that was sufficient to attenuate ZH501. However, strain MP-12 with reversion mutations at those 3 sites was still highly attenuated. Our results indicate that MP-12 attenuation is supported by a combination of multiple partial attenuation mutations and a single reversion mutation is less likely to cause a reversion to virulence of the MP-12 vaccine. IMPORTANCE Rift Valley fever (RVF) is a mosquito-transmitted viral disease that is endemic to Africa and that has the potential to spread into other countries. Vaccination is considered an effective way to prevent the disease, and the only available veterinary RVF vaccine in the United States is a live-attenuated MP-12 vaccine, which is conditionally licensed. Strain MP-12 is different from its parental pathogenic RVFV strain, strain ZH548, because of the presence of 23 mutations. This study determined the role of individual mutations in the attenuation of the MP-12 strain. We found that full attenuation of MP-12 occurs by a combination of multiple mutations. Our findings indicate that a single reversion mutation will less likely cause a major reversion to virulence of the MP-12 vaccine. PMID:25948740
Ikegami, Tetsuro; Hill, Terence E; Smith, Jennifer K; Zhang, Lihong; Juelich, Terry L; Gong, Bin; Slack, Olga A L; Ly, Hoai J; Lokugamage, Nandadeva; Freiberg, Alexander N
2015-07-01
Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to Africa and characterized by a high rate of abortion in ruminants and hemorrhagic fever, encephalitis, or blindness in humans. RVF is caused by Rift Valley fever virus (RVFV; family Bunyaviridae, genus Phlebovirus), which has a tripartite negative-stranded RNA genome (consisting of the S, M, and L segments). Further spread of RVF into countries where the disease is not endemic may affect the economy and public health, and vaccination is an effective approach to prevent the spread of RVFV. A live-attenuated MP-12 vaccine is one of the best-characterized RVF vaccines for safety and efficacy and is currently conditionally licensed for use for veterinary purposes in the United States. Meanwhile, as of 2015, no other RVF vaccine has been conditionally or fully licensed for use in the United States. The MP-12 strain is derived from wild-type pathogenic strain ZH548, and its genome encodes 23 mutations in the three genome segments. However, the mechanism of MP-12 attenuation remains unknown. We characterized the attenuation of wild-type pathogenic strain ZH501 carrying a mutation(s) of the MP-12 S, M, or L segment in a mouse model. Our results indicated that MP-12 is attenuated by the mutations in the S, M, and L segments, while the mutations in the M and L segments confer stronger attenuation than those in the S segment. We identified a combination of 3 amino acid changes, Y259H (Gn), R1182G (Gc), and R1029K (L), that was sufficient to attenuate ZH501. However, strain MP-12 with reversion mutations at those 3 sites was still highly attenuated. Our results indicate that MP-12 attenuation is supported by a combination of multiple partial attenuation mutations and a single reversion mutation is less likely to cause a reversion to virulence of the MP-12 vaccine. Rift Valley fever (RVF) is a mosquito-transmitted viral disease that is endemic to Africa and that has the potential to spread into other countries. Vaccination is considered an effective way to prevent the disease, and the only available veterinary RVF vaccine in the United States is a live-attenuated MP-12 vaccine, which is conditionally licensed. Strain MP-12 is different from its parental pathogenic RVFV strain, strain ZH548, because of the presence of 23 mutations. This study determined the role of individual mutations in the attenuation of the MP-12 strain. We found that full attenuation of MP-12 occurs by a combination of multiple mutations. Our findings indicate that a single reversion mutation will less likely cause a major reversion to virulence of the MP-12 vaccine. Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Attenuation, dispersion and nonlinearity effects in graphene-based waveguides
Mota, João Cesar Moura; Sombra, Antonio Sergio Bezerra
2015-01-01
Summary We simulated and analyzed in detail the behavior of ultrashort optical pulses, which are typically used in telecommunications, propagating through graphene-based nanoribbon waveguides. In this work, we showed the changes that occur in the Gaussian and hyperbolic secant input pulses due to the attenuation, high-order dispersive effects and nonlinear effects. We concluded that it is possible to control the shape of the output pulses with the value of the input signal power and the chemical potential of the graphene nanoribbon. We believe that the obtained results will be highly relevant since they can be applied to other nanophotonic devices, for example, filters, modulators, antennas, switches and other devices. PMID:26171299
Cai, Yi; Chew, Cory; Muñoz, Fernando; Sengelaub, Dale R
2017-06-01
Partial depletion of spinal motoneuron populations induces dendritic atrophy in neighboring motoneurons, and treatment with testosterone is neuroprotective, attenuating induced dendritic atrophy. In this study we examined whether the protective effects of testosterone could be mediated via its androgenic or estrogenic metabolites. Furthermore, to assess whether these neuroprotective effects were mediated through steroid hormone receptors, we used receptor antagonists to attempt to prevent the neuroprotective effects of hormones after partial motoneuron depletion. Motoneurons innervating the vastus medialis muscles of adult male rats were selectively killed by intramuscular injection of cholera toxin-conjugated saporin. Simultaneously, some saporin-injected rats were treated with either dihydrotestosterone or estradiol, alone or in combination with their respective receptor antagonists, or left untreated. Four weeks later, motoneurons innervating the ipsilateral vastus lateralis muscle were labeled with cholera toxin-conjugated horseradish peroxidase, and dendritic arbors were reconstructed in three dimensions. Compared with intact normal animals, partial motoneuron depletion resulted in decreased dendritic length in remaining quadriceps motoneurons. Dendritic atrophy was attenuated with both dihydrotestosterone and estradiol treatment to a degree similar to that seen with testosterone, and attenuation of atrophy was prevented by receptor blockade. Together, these findings suggest that neuroprotective effects on motoneurons can be mediated by either androgenic or estrogenic hormones and require action via steroid hormone receptors, further supporting a role for hormones as neurotherapeutic agents in the injured nervous system. © 2016 Wiley Periodicals, Inc. Develop Neurobiol 77: 691-707, 2017. © 2016 Wiley Periodicals, Inc.
In vitro attenuation of impact shock in equine digits.
Lanovaz, J L; Clayton, H M; Watson, L G
1998-09-01
This study was designed to test the impact characteristics of the equine digit in vitro with the objective of providing a better understanding of the role of the digital structures in the attenuation of impact shock. Uni-axial accelerometers were mounted on cadaver digits on the distolateral hoof wall, the proximolateral hoof wall, the dorsal surface of the second phalanx, and the mid-lateral first phalanx. The hoof-mounted accelerometers were aligned with the hoof tubules while the bone-mounted accelerometers were oriented along the longitudinal axis of the bone. Each digit was mounted in a test apparatus designed to simulate impact of the hoof with the ground during locomotion. The digits were subjected to 3 impact trials against a barrier at each of 3 vertical impact velocities that simulated a forward trotting velocity in the range of 2.67 to 4.46 m/s. The impact deceleration tended to increase with impact velocity. Attenuation of the impact shock by the digital tissues resulted in a reduction in impact decleration in the more proximal measuring locations. The interphalangeal joints appeared to play a larger role in amplitude attenuation than the hoof wall or the soft tissue structures within the hoof wall. The signal frequency data showed that the soft tissues within the hoof acted as a 'lowpass' filter, attenuating the higher deceleration frequencies. The hoof wall and the interphalangeal joints showed little frequency attenuation.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-12
... Serial No. 12/149,076, entitled ``Combinations of Gene Deletions for Live Attenuated Shigella Vaccine.... SUPPLEMENTARY INFORMATION: The invention relates generally to Shigella vaccine, strains, their use in vaccines...
NASA Astrophysics Data System (ADS)
Nishino, Hideo; Tateishi, Kohei; Ishikawa, Masashi; Furukawa, Takashi; Goka, Motoki
2018-07-01
Guided wave inspection is expected especially for buried piping because it can be applied easily to such piping requiring only its partial digging from the ground. However, in buried piping, the attenuation coefficient is extremely large compared with that in above-ground piping because the leaky \\text{T}(0,1) mode guided wave (LTGW) propagates in buried piping and its energy leaks into the adjacent surrounding material as a bulk shear wave. Petrolatum anticorrosion grease (PAG) is the most widely used as the coating material on the pipe surface before burying piping in sand or soil, which is a viscous material with a temperature-dependent shear wave velocity. In this paper, attenuation characteristics of the LTGW are shown theoretically and experimentally. The theoretical calculations explain very well the experimental results measured. The temperature dependence of the attenuation coefficient is discussed with the theoretical outcomes.
Water saturation effects on elastic wave attenuation in porous rocks with aligned fractures
NASA Astrophysics Data System (ADS)
Amalokwu, Kelvin; Best, Angus I.; Sothcott, Jeremy; Chapman, Mark; Minshull, Tim; Li, Xiang-Yang
2014-05-01
Elastic wave attenuation anisotropy in porous rocks with aligned fractures is of interest to seismic remote sensing of the Earth's structure and to hydrocarbon reservoir characterization in particular. We investigated the effect of partial water saturation on attenuation in fractured rocks in the laboratory by conducting ultrasonic pulse-echo measurements on synthetic, silica-cemented, sandstones with aligned penny-shaped voids (fracture density of 0.0298 ± 0.0077), chosen to simulate the effect of natural fractures in the Earth according to theoretical models. Our results show, for the first time, contrasting variations in the attenuation (Q-1) of P and S waves with water saturation in samples with and without fractures. The observed Qs/Qp ratios are indicative of saturation state and the presence or absence of fractures, offering an important new possibility for remote fluid detection and characterization.
Fractal ladder models and power law wave equations
Kelly, James F.; McGough, Robert J.
2009-01-01
The ultrasonic attenuation coefficient in mammalian tissue is approximated by a frequency-dependent power law for frequencies less than 100 MHz. To describe this power law behavior in soft tissue, a hierarchical fractal network model is proposed. The viscoelastic and self-similar properties of tissue are captured by a constitutive equation based on a lumped parameter infinite-ladder topology involving alternating springs and dashpots. In the low-frequency limit, this ladder network yields a stress-strain constitutive equation with a time-fractional derivative. By combining this constitutive equation with linearized conservation principles and an adiabatic equation of state, a fractional partial differential equation that describes power law attenuation is derived. The resulting attenuation coefficient is a power law with exponent ranging between 1 and 2, while the phase velocity is in agreement with the Kramers–Kronig relations. The fractal ladder model is compared to published attenuation coefficient data, thus providing equivalent lumped parameters. PMID:19813816
Gonzalez-Estrella, Jorge; Gallagher, Sara; Sierra-Alvarez, Reyes; Field, Jim A.
2016-01-01
Elemental copper (Cu0) and zinc oxide (ZnO) nanoparticle (NP) toxicity to methanogens has been attributed to the release of soluble metal ions. Iron sulfide (FeS) partially controls the soluble concentration of heavy metals and their toxicity in aquatic environments. Heavy metals displace the Fe from FeS forming poorly soluble metal sulfides in the FeS matrix. Therefore, FeS may be expected to attenuate the NP toxicity. This work assessed FeS as an attenuator of the methanogenic toxicity of Cu0 and ZnO NPs and their soluble salt analogs. The toxicity attenuation capacity of fine (25–75 µm) and coarse (500 to 1200 µm) preparations of FeS (FeS-f and FeS-c respectively) was tested in the presence of highly inhibitory concentrations of CuCl2, ZnCl2 Cu0 and ZnO NPs. FeS-f attenuated methanogenic toxicity better than FeS-c. The results revealed that 2.5× less FeS-f than FeS-c was required to recover the methanogenic activity to 50% (activity normalized to uninhibited controls). The results also indicated that a molar FeS-f/Cu0 NP, FeS-f/ZnO NP, FeS-f/ZnCl2, and FeS-f/CuCl2 ratio of 2.14, 2.14, 4.28, and 8.56 respectively, was necessary to recover the methanogenic activity to >75%. Displacement experiments demonstrated that CuCl2 and ZnCl2 partially displaced Fe from FeS. As a whole, the results indicate that not all the sulfide in FeS was readily available to react with the soluble Cu and Zn ions which may explain the need for a large stoichiometric excesses of FeS to highly attenuate Cu and Zn toxicity. Overall, this study provides evidence that FeS attenuates the toxicity caused by Cu0 and ZnO NPs and their soluble ion analogs to methanogens. PMID:26803736
Larson, Nels R. [Pacific Northwest Laboratory (PNNL), Richland, WA (USA); Michalsky, Joseph J. [Atmospheric Sciences Research Center, Albany, NY (USA); LeBaron, Brock A. [Utah Bureau of Air Quality, Salt Lake City, Utah (USA)
2012-01-01
Surface measurements of solar irradiance of the atmosphere were made by a multipurpose computer-controlled scanning photometer at the Rattlesnake Mountain Observatory in eastern Washington. The observatory is located at 46.4° N, 119.6° W at an elevation of 1088 m above mean sea level. The photometer measures the attenuation of direct solar radiation for different wavelengths using 12 filters. Five of these filters (i.e., at 428 nm, 486 nm, 535 nm, 785 nm, and 1010 nm, with respective half-power widths of 2, 2, 3, 18, and 28 nm) are suitable for monitoring variations in the total optical depth of the atmosphere.
Neutron Transmission of Single-crystal Sapphire Filters
NASA Astrophysics Data System (ADS)
Adib, M.; Kilany, M.; Habib, N.; Fathallah, M.
2005-05-01
An additive formula is given that permits the calculation of the nuclear capture, thermal diffuse and Bragg scattering cross-sections as a function of sapphire temperature and crystal parameters. We have developed a computer program that allows calculations of the thermal neutron transmission for the sapphire rhombohedral structure and its equivalent trigonal structure. The calculated total cross-section values and effective attenuation coefficient for single-crystalline sapphire at different temperatures are compared with measured values. Overall agreement is indicated between the formula and experimental data. We discuss the use of sapphire single crystal as a thermal neutron filter in terms of the optimum cystal thickness, mosaic spread, temperature, cutting plane and tuning for efficient transmission of thermal-reactor neutrons.
CH PLIF and PIV implementation using C-X (0,0) and intra-vibrational band filtered detection
NASA Astrophysics Data System (ADS)
Hammack, Stephen D.; Skiba, Aaron W.; Lee, Tonghun; Carter, Campbell D.
2018-02-01
This study demonstrates advancement in a low-pulse energy methylidyne (CH) planar laser-induced fluorescence (PLIF) method that facilitates its application alongside flows seeded for particle image velocimetry (PIV) or other particle scattering based methods, as well as in high scattering environments. The C-X (0,0) R-branch excitation and filtered detection are carefully selected such that the laser line frequency is heavily attenuated by an edge filter while allowing transmission of most of the (0,0) band fluorescence. There are strong OH A-X (0,0) lines in the vicinity, but they can be avoided or utilized through dye laser tuning. As a demonstration of efficacy, PIV is performed simultaneously with the PLIF imaging. Using the edge filter, particle scattering signal is reduced to sub-fluorescence levels, allowing for flame-front analysis. This achievement enables flame-front tracking at high repetition rates (due to the low-pulse energy required) in combination with a scattering method such as PIV or use in high scattering environments such as enclosed combustors or near burner surfaces.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liu, T; Lin, H; Gao, Y
Purpose: Dynamic bowtie filter is an innovative design capable of modulating the X-ray and balancing the flux in the detectors, and it introduces a new way of patient-specific CT scan optimizations. This study demonstrates the feasibility of performing fast Monte Carlo dose calculation for a type of dynamic bowtie filter for cone-beam CT (Liu et al. 2014 9(7) PloS one) using MIC coprocessors. Methods: The dynamic bowtie filter in question consists of a highly attenuating bowtie component (HB) and a weakly attenuating bowtie (WB). The HB is filled with CeCl3 solution and its surface is defined by a transcendental equation.more » The WB is an elliptical cylinder filled with air and immersed in the HB. As the scanner rotates, the orientation of WB remains the same with the static patient. In our Monte Carlo simulation, the HB was approximated by 576 boxes. The phantom was a voxelized elliptical cylinder composed of PMMA and surrounded by air (44cm×44cm×40cm, 1000×1000×1 voxels). The dose to the PMMA phantom was tallied with 0.15% statistical uncertainty under 100 kVp source. Two Monte Carlo codes ARCHER and MCNP-6.1 were compared. Both used double-precision. Compiler flags that may trade accuracy for speed were avoided. Results: The wall time of the simulation was 25.4 seconds by ARCHER on a 5110P MIC, 40 seconds on a X5650 CPU, and 523 seconds by the multithreaded MCNP on the same CPU. The high performance of ARCHER is attributed to the parameterized geometry and vectorization of the program hotspots. Conclusion: The dynamic bowtie filter modeled in this study is able to effectively reduce the dynamic range of the detected signals for the photon-counting detectors. With appropriate software optimization methods, the accelerator-based (MIC and GPU) Monte Carlo dose engines have shown good performance and can contribute to patient-specific CT scan optimizations.« less
An excitation wavelength-scanning spectral imaging system for preclinical imaging
NASA Astrophysics Data System (ADS)
Leavesley, Silas; Jiang, Yanan; Patsekin, Valery; Rajwa, Bartek; Robinson, J. Paul
2008-02-01
Small-animal fluorescence imaging is a rapidly growing field, driven by applications in cancer detection and pharmaceutical therapies. However, the practical use of this imaging technology is limited by image-quality issues related to autofluorescence background from animal tissues, as well as attenuation of the fluorescence signal due to scatter and absorption. To combat these problems, spectral imaging and analysis techniques are being employed to separate the fluorescence signal from background autofluorescence. To date, these technologies have focused on detecting the fluorescence emission spectrum at a fixed excitation wavelength. We present an alternative to this technique, an imaging spectrometer that detects the fluorescence excitation spectrum at a fixed emission wavelength. The advantages of this approach include increased available information for discrimination of fluorescent dyes, decreased optical radiation dose to the animal, and ability to scan a continuous wavelength range instead of discrete wavelength sampling. This excitation-scanning imager utilizes an acousto-optic tunable filter (AOTF), with supporting optics, to scan the excitation spectrum. Advanced image acquisition and analysis software has also been developed for classification and unmixing of the spectral image sets. Filtering has been implemented in a single-pass configuration with a bandwidth (full width at half maximum) of 16nm at 550nm central diffracted wavelength. We have characterized AOTF filtering over a wide range of incident light angles, much wider than has been previously reported in the literature, and we show how changes in incident light angle can be used to attenuate AOTF side lobes and alter bandwidth. A new parameter, in-band to out-of-band ratio, was defined to assess the quality of the filtered excitation light. Additional parameters were measured to allow objective characterization of the AOTF and the imager as a whole. This is necessary for comparing the excitation-scanning imager to other spectral and fluorescence imaging technologies. The effectiveness of the hyperspectral imager was tested by imaging and analysis of mice with injected fluorescent dyes. Finally, a discussion of the optimization of spectral fluorescence imagers is given, relating the effects of filter quality on fluorescence images collected and the analysis outcome.
NASA Astrophysics Data System (ADS)
Liu, Wen; Zhang, Yuying; Yang, Si; Han, Donghai
2018-05-01
A new technique to identify the floral resources of honeys is demanded. Terahertz time-domain attenuated total reflection spectroscopy combined with chemometrics methods was applied to discriminate different categorizes (Medlar honey, Vitex honey, and Acacia honey). Principal component analysis (PCA), cluster analysis (CA) and partial least squares-discriminant analysis (PLS-DA) have been used to find information of the botanical origins of honeys. Spectral range also was discussed to increase the precision of PLS-DA model. The accuracy of 88.46% for validation set was obtained, using PLS-DA model in 0.5-1.5 THz. This work indicated terahertz time-domain attenuated total reflection spectroscopy was an available approach to evaluate the quality of honey rapidly.
Gregori, Josep; Villarreal, Laura; Sánchez, Alex; Baselga, José; Villanueva, Josep
2013-12-16
The microarray community has shown that the low reproducibility observed in gene expression-based biomarker discovery studies is partially due to relying solely on p-values to get the lists of differentially expressed genes. Their conclusions recommended complementing the p-value cutoff with the use of effect-size criteria. The aim of this work was to evaluate the influence of such an effect-size filter on spectral counting-based comparative proteomic analysis. The results proved that the filter increased the number of true positives and decreased the number of false positives and the false discovery rate of the dataset. These results were confirmed by simulation experiments where the effect size filter was used to evaluate systematically variable fractions of differentially expressed proteins. Our results suggest that relaxing the p-value cut-off followed by a post-test filter based on effect size and signal level thresholds can increase the reproducibility of statistical results obtained in comparative proteomic analysis. Based on our work, we recommend using a filter consisting of a minimum absolute log2 fold change of 0.8 and a minimum signal of 2-4 SpC on the most abundant condition for the general practice of comparative proteomics. The implementation of feature filtering approaches could improve proteomic biomarker discovery initiatives by increasing the reproducibility of the results obtained among independent laboratories and MS platforms. Quality control analysis of microarray-based gene expression studies pointed out that the low reproducibility observed in the lists of differentially expressed genes could be partially attributed to the fact that these lists are generated relying solely on p-values. Our study has established that the implementation of an effect size post-test filter improves the statistical results of spectral count-based quantitative proteomics. The results proved that the filter increased the number of true positives whereas decreased the false positives and the false discovery rate of the datasets. The results presented here prove that a post-test filter applying a reasonable effect size and signal level thresholds helps to increase the reproducibility of statistical results in comparative proteomic analysis. Furthermore, the implementation of feature filtering approaches could improve proteomic biomarker discovery initiatives by increasing the reproducibility of results obtained among independent laboratories and MS platforms. This article is part of a Special Issue entitled: Standardization and Quality Control in Proteomics. Copyright © 2013 Elsevier B.V. All rights reserved.
von Spiczak, Jochen; Mannil, Manoj; Peters, Benjamin; Hickethier, Tilman; Baer, Matthias; Henning, André; Schmidt, Bernhard; Flohr, Thomas; Manka, Robert; Maintz, David; Alkadhi, Hatem
2018-05-23
The aims of this study were to assess the value of a dedicated sharp convolution kernel for photon counting detector (PCD) computed tomography (CT) for coronary stent imaging and to evaluate to which extent iterative reconstructions can compensate for potential increases in image noise. For this in vitro study, a phantom simulating coronary artery stenting was prepared. Eighteen different coronary stents were expanded in plastic tubes of 3 mm diameter. Tubes were filled with diluted contrast agent, sealed, and immersed in oil calibrated to an attenuation of -100 HU simulating epicardial fat. The phantom was scanned in a modified second generation 128-slice dual-source CT scanner (SOMATOM Definition Flash, Siemens Healthcare, Erlangen, Germany) equipped with both a conventional energy integrating detector and PCD. Image data were acquired using the PCD part of the scanner with 48 × 0.25 mm slices, a tube voltage of 100 kVp, and tube current-time product of 100 mAs. Images were reconstructed using a conventional convolution kernel for stent imaging with filtered back-projection (B46) and with sinogram-affirmed iterative reconstruction (SAFIRE) at level 3 (I463). For comparison, a dedicated sharp convolution kernel with filtered back-projection (D70) and SAFIRE level 3 (Q703) and level 5 (Q705) was used. The D70 and Q70 kernels were specifically designed for coronary stent imaging with PCD CT by optimizing the image modulation transfer function and the separation of contrast edges. Two independent, blinded readers evaluated subjective image quality (Likert scale 0-3, where 3 = excellent), in-stent diameter difference, in-stent attenuation difference, mathematically defined image sharpness, and noise of each reconstruction. Interreader reliability was calculated using Goodman and Kruskal's γ and intraclass correlation coefficients (ICCs). Differences in image quality were evaluated using a Wilcoxon signed-rank test. Differences in in-stent diameter difference, in-stent attenuation difference, image sharpness, and image noise were tested using a paired-sample t test corrected for multiple comparisons. Interreader and intrareader reliability were excellent (γ = 0.953, ICCs = 0.891-0.999, and γ = 0.996, ICCs = 0.918-0.999, respectively). Reconstructions using the dedicated sharp convolution kernel yielded significantly better results regarding image quality (B46: 0.4 ± 0.5 vs D70: 2.9 ± 0.3; P < 0.001), in-stent diameter difference (1.5 ± 0.3 vs 1.0 ± 0.3 mm; P < 0.001), and image sharpness (728 ± 246 vs 2069 ± 411 CT numbers/voxel; P < 0.001). Regarding in-stent attenuation difference, no significant difference was observed between the 2 kernels (151 ± 76 vs 158 ± 92 CT numbers; P = 0.627). Noise was significantly higher in all sharp convolution kernel images but was reduced by 41% and 59% by applying SAFIRE levels 3 and 5, respectively (B46: 16 ± 1, D70: 111 ± 3, Q703: 65 ± 2, Q705: 46 ± 2 CT numbers; P < 0.001 for all comparisons). A dedicated sharp convolution kernel for PCD CT imaging of coronary stents yields superior qualitative and quantitative image characteristics compared with conventional reconstruction kernels. Resulting higher noise levels in sharp kernel PCD imaging can be partially compensated with iterative image reconstruction techniques.
An Investigation Into Low Fuel Pressure Warnings on a Macchi-Viper Aircraft
1988-05-01
was sufficient To activate the low pressure warning light. The pressure switch is normally set to a differential of between 2.5 - 3 psi. Partial...only a 2.1 psig margin for light illumination, if the pressure switch is set at 3 psig, and gives little scope for extra pipe or filter losses when... pressure switch is set between 2.5 - 3 psig. Any untoward pressure resistance in the fuel delivery line and filtering system would soon erode this
Investigation of Pseudo Bi-Polar Nickel Cadmium Batteries as Filter Elements for Pulsed Power Loads.
1984-12-01
FOR PULSED POWER LOADS THESIS Michael B. Cimino Gregory M. Gearing Major, USAF Captain, USAF AFIT/GE/ENG/84D-1B DTIC SECETE D~rR~fl"N STATEMENT A...LOADS THESIS Presented to the Faculty of the School of Engineering of the Air Force Institute of Technology Air University In Partial Fulfillment of...with the intent to make batteries capable of out performing capacitors as power supply filters. Purpose This thesis investigated the use of nickel
Seismic evidence for broad attenuation anomalies in the asthenosphere beneath the Pacific Ocean
NASA Astrophysics Data System (ADS)
Adenis, Alice; Debayle, Eric; Ricard, Yanick
2017-06-01
We present QADR17, a global model of Rayleigh-wave attenuation based on a massive surface wave data set (372 629 frequency-dependent attenuation curves in the period range 50-260 s). We correct for focusing-defocusing effects and geometrical spreading, and perform a stringent selection to only keep robust observations. Then, data with close epicentres recorded at the same station are clustered, as they sample the same Earth's structure. After this pre-selection, our data set consists of about 35 000 curves that constrain the Rayleigh-wave intrinsic attenuation in the upper mantle. The logarithms of the attenuation along the individual rays are then inverted to obtain global maps of the logarithm of the local attenuation. After a first inversion, outliers are rejected and a second inversion yields a variance reduction of about 45 per cent. Our attenuation maps present strong agreement with surface tectonics at periods lower than 200 s, with low attenuation under continents and high attenuation under oceans. Over oceans, attenuation decreases with increasing crustal ages, but at periods sensitive to the uppermost 150 km, mid-ocean ridges are not characterized by a very localized anomaly, in contrast to what is commonly observed for seismic velocity models. Attenuation is rather well correlated with hotspots, especially in the Pacific ocean, where a strong attenuating anomaly is observed in the long wavelength component of our signal at periods sampling the oceanic asthenosphere. We suggest that this anomaly results from the horizontal spreading of several thermal plumes within the asthenosphere. Strong velocity reductions associated with high attenuation anomalies of moderate amplitudes beneath the East Pacific Rise, the Red Sea and the eastern part of Asia may require additional mechanisms, such as partial melting.
Burau, J.R.; Simpson, M.R.; Cheng, R.T.
1993-01-01
Water-velocity profiles were collected at the west end of Carquinez Strait, San Francisco Bay, California, from March to November 1988, using an acoustic Doppler current profiler (ADCP). These data are a series of 10-minute-averaged water velocities collected at 1-meter vertical intervals (bins) in the 16.8-meter water column, beginning 2.1 meters above the estuary bed. To examine the vertical structure of the horizontal water velocities, the data are separated into individual time-series by bin and then used for time-series plots, harmonic analysis, and for input to digital filters. Three-dimensional graphic renditions of the filtered data are also used in the analysis. Harmonic analysis of the time-series data from each bin indicates that the dominant (12.42 hour or M2) partial tidal currents reverse direction near the bottom, on average, 20 minutes sooner than M2 partial tidal currents near the surface. Residual (nontidal) currents derived from the filtered data indicate that currents near the bottom are pre- dominantly up-estuary during the neap tides and down-estuary during the more energetic spring tides.
NASA Astrophysics Data System (ADS)
Civale, John; Ter Haar, Gail; Rivens, Ian; Bamber, Jeff
2005-09-01
Currently, the intensity to be used in our clinical HIFU treatments is calculated from the acoustic path lengths in different tissues measured on diagnostic ultrasound images of the patient in the treatment position, and published values of ultrasound attenuation coefficients. This yields an approximate value for the acoustic power at the transducer required to give a stipulated focal intensity in situ. Estimation methods for the actual acoustic attenuation have been investigated in large parts of the tissue path overlying the target volume from the backscattered ultrasound signal for each patient (backscatter attenuation estimation: BAE). Several methods have been investigated. The backscattered echo information acquired from an Acuson scanner has been used to compute the diffraction-corrected attenuation coefficient at each frequency using two methods: a substitution method and an inverse diffraction filtering process. A homogeneous sponge phantom was used to validate the techniques. The use of BAE to determine the correct HIFU exposure parameters for lesioning has been tested in ex vivo liver. HIFU lesions created with a 1.7-MHz therapy transducer have been studied using a semiautomated image processing technique. The reproducibility of lesion size for given in situ intensities determined using BAE and empirical techniques has been compared.
Finite-time H∞ filtering for non-linear stochastic systems
NASA Astrophysics Data System (ADS)
Hou, Mingzhe; Deng, Zongquan; Duan, Guangren
2016-09-01
This paper describes the robust H∞ filtering analysis and the synthesis of general non-linear stochastic systems with finite settling time. We assume that the system dynamic is modelled by Itô-type stochastic differential equations of which the state and the measurement are corrupted by state-dependent noises and exogenous disturbances. A sufficient condition for non-linear stochastic systems to have the finite-time H∞ performance with gain less than or equal to a prescribed positive number is established in terms of a certain Hamilton-Jacobi inequality. Based on this result, the existence of a finite-time H∞ filter is given for the general non-linear stochastic system by a second-order non-linear partial differential inequality, and the filter can be obtained by solving this inequality. The effectiveness of the obtained result is illustrated by a numerical example.
Frequency response of the renal vasculature in congestive heart failure.
DiBona, Gerald F; Sawin, Linda L
2003-04-29
The renal vasoconstrictor response to renal nerve stimulation is greater in congestive heart failure (CHF) rats than in control rats. This study tested the hypothesis that the enhanced renal vasoconstrictor response to renal nerve stimulation in CHF is a result of an impairment in the low-pass filter function of the renal vasculature. In response to conventional graded-frequency renal nerve stimulation, the reductions in renal blood flow at each stimulation frequency were greater in CHF rats than control rats. A pseudorandom binary sequence pattern of renal nerve stimulation was used to examine the frequency response of the renal vasculature. Although this did not affect the renal blood flow power spectrum in control rats, there was a 10-fold increase in renal blood flow power over the frequency range of 0.01 to 1.0 Hz in CHF rats. On analysis of transfer function gain, attenuation of the renal nerve stimulation input signal was similar in control and CHF rats over the frequency range of 0.001 to 0.1 Hz. However, over the frequency range of 0.1 to 1.0 Hz, although there was progressive attenuation of the input signal (-30 to -70 dB) in control rats, CHF rats exhibited a flat gain response (-20 dB) without progressive attenuation. The enhanced renal vasoconstrictor response to renal nerve stimulation in CHF rats is caused by an alteration in the low-pass filter function of the renal vasculature, resulting in a greater transfer of input signals into renal blood flow in the 0.1 to 1.0 Hz range.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-12
... Serial No. 11/132,199, entitled ``Construction of Live Attenuated Shigella Vaccine Strains that Express... proteins in Shigella spp. without affecting the ability of the Shigella strain to invade cells of the...
NASA Astrophysics Data System (ADS)
Kurudirek, Murat; Türkmen, İbrahim; Özdemir, Yüksel
2009-09-01
Total mass attenuation coefficients, mean free paths (MFP), half-value (HVT) and tenth-value (TVT) thicknesses of Portland cement and three mixtures have been calculated in function of the energy from 1 keV to 100 GeV. Both in the low- and high-energy region there were significant variations in those parameters where photoelectric process and pair production partially dominates, respectively. In general, the attenuation parameters were found to vary with chemical composition, density of given material and photon energy.
Image denoising by sparse 3-D transform-domain collaborative filtering.
Dabov, Kostadin; Foi, Alessandro; Katkovnik, Vladimir; Egiazarian, Karen
2007-08-01
We propose a novel image denoising strategy based on an enhanced sparse representation in transform domain. The enhancement of the sparsity is achieved by grouping similar 2-D image fragments (e.g., blocks) into 3-D data arrays which we call "groups." Collaborative filtering is a special procedure developed to deal with these 3-D groups. We realize it using the three successive steps: 3-D transformation of a group, shrinkage of the transform spectrum, and inverse 3-D transformation. The result is a 3-D estimate that consists of the jointly filtered grouped image blocks. By attenuating the noise, the collaborative filtering reveals even the finest details shared by grouped blocks and, at the same time, it preserves the essential unique features of each individual block. The filtered blocks are then returned to their original positions. Because these blocks are overlapping, for each pixel, we obtain many different estimates which need to be combined. Aggregation is a particular averaging procedure which is exploited to take advantage of this redundancy. A significant improvement is obtained by a specially developed collaborative Wiener filtering. An algorithm based on this novel denoising strategy and its efficient implementation are presented in full detail; an extension to color-image denoising is also developed. The experimental results demonstrate that this computationally scalable algorithm achieves state-of-the-art denoising performance in terms of both peak signal-to-noise ratio and subjective visual quality.
NASA Astrophysics Data System (ADS)
Tan, Jun; Song, Peng; Li, Jinshan; Wang, Lei; Zhong, Mengxuan; Zhang, Xiaobo
2017-06-01
The surface-related multiple elimination (SRME) method is based on feedback formulation and has become one of the most preferred multiple suppression methods used. However, some differences are apparent between the predicted multiples and those in the source seismic records, which may result in conventional adaptive multiple subtraction methods being barely able to effectively suppress multiples in actual production. This paper introduces a combined adaptive multiple attenuation method based on the optimized event tracing technique and extended Wiener filtering. The method firstly uses multiple records predicted by SRME to generate a multiple velocity spectrum, then separates the original record to an approximate primary record and an approximate multiple record by applying the optimized event tracing method and short-time window FK filtering method. After applying the extended Wiener filtering method, residual multiples in the approximate primary record can then be eliminated and the damaged primary can be restored from the approximate multiple record. This method combines the advantages of multiple elimination based on the optimized event tracing method and the extended Wiener filtering technique. It is an ideal method for suppressing typical hyperbolic and other types of multiples, with the advantage of minimizing damage of the primary. Synthetic and field data tests show that this method produces better multiple elimination results than the traditional multi-channel Wiener filter method and is more suitable for multiple elimination in complicated geological areas.
An Optimal Partial Differential Equations-based Stopping Criterion for Medical Image Denoising.
Khanian, Maryam; Feizi, Awat; Davari, Ali
2014-01-01
Improving the quality of medical images at pre- and post-surgery operations are necessary for beginning and speeding up the recovery process. Partial differential equations-based models have become a powerful and well-known tool in different areas of image processing such as denoising, multiscale image analysis, edge detection and other fields of image processing and computer vision. In this paper, an algorithm for medical image denoising using anisotropic diffusion filter with a convenient stopping criterion is presented. In this regard, the current paper introduces two strategies: utilizing the efficient explicit method due to its advantages with presenting impressive software technique to effectively solve the anisotropic diffusion filter which is mathematically unstable, proposing an automatic stopping criterion, that takes into consideration just input image, as opposed to other stopping criteria, besides the quality of denoised image, easiness and time. Various medical images are examined to confirm the claim.
SU-C-207-04: Reconstruction Artifact Reduction in X-Ray Cone Beam CT Using a Treatment Couch Model
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lasio, G; Hu, E; Zhou, J
2015-06-15
Purpose: to mitigate artifacts induced by the presence of the RT treatment couch in on-board CBCT and improve image quality Methods: a model of a Varian IGRT couch is constructed using a CBCT scan of the couch in air. The model is used to generate a set of forward projections (FP) of the treatment couch at specified gantry angles. The model couch forward projections are then used to process CBCT scan projections which contain the couch in addition to the scan object (Catphan phantom), in order to remove the attenuation component of the couch at any given gantry angle. Priormore » to pre-processing with the model FP, the Catphan projection data is normalized to an air scan with bowtie filter. The filtered Catphan projections are used to reconstruct the CBCT with an in-house FDK algorithm. The artifact reduction in the processed CBCT scan is assessed visually, and the image quality improvement is measured with the CNR over a few selected ROIs of the Catphan modules. Results: Sufficient match between the forward projected data and the x-ray projections is achieved to allow filtering in attenuation space. Visual improvement of the couch induced artifacts is achieved, with a moderate expense of CNR. Conclusion: Couch model-based correction of CBCT projection data has a potential for qualitative improvement of clinical CBCT scans, without requiring position specific correction data. The technique could be used to produce models of other artifact inducing devices, such as immobilization boards, and reduce their impact on patient CBCT images.« less
NASA Astrophysics Data System (ADS)
Setlur Nagesh, S. V.; Khobragade, P.; Ionita, C.; Bednarek, D. R.; Rudin, S.
2015-03-01
Because x-ray based image-guided vascular interventions are minimally invasive they are currently the most preferred method of treating disorders such as stroke, arterial stenosis, and aneurysms; however, the x-ray exposure to the patient during long image-guided interventional procedures could cause harmful effects such as cancer in the long run and even tissue damage in the short term. ROI fluoroscopy reduces patient dose by differentially attenuating the incident x-rays outside the region-of-interest. To reduce the noise in the dose-reduced regions previously recursive temporal filtering was successfully demonstrated for neurovascular interventions. However, in cardiac interventions, anatomical motion is significant and excessive recursive filtering could cause blur. In this work the effects of three noise-reduction schemes, including recursive temporal filtering, spatial mean filtering, and a combination of spatial and recursive temporal filtering, were investigated in a simulated ROI dose-reduced cardiac intervention. First a model to simulate the aortic arch and its movement was built. A coronary stent was used to simulate a bioprosthetic valve used in TAVR procedures and was deployed under dose-reduced ROI fluoroscopy during the simulated heart motion. The images were then retrospectively processed for noise reduction in the periphery, using recursive temporal filtering, spatial filtering and a combination of both. Quantitative metrics for all three noise reduction schemes are calculated and are presented as results. From these it can be concluded that with significant anatomical motion, a combination of spatial and recursive temporal filtering scheme is best suited for reducing the excess quantum noise in the periphery. This new noise-reduction technique in combination with ROI fluoroscopy has the potential for substantial patient-dose savings in cardiac interventions.
2008-06-03
etiologic agent of glanders in solipeds (horses, mules and donkeys), and incidentally in carnivores and humans. Little is known about the molecular...disintegrated cell envelopes. Furthermore, relative to the wild type, the ctpA mutant displayed slower growth in vitro and less ability to survive in...IgG2a and were partially protected against chal- lenge with wild type B. mallei ATCC 23344. These findings suggest that CtpA regulates in vitro growth
NASA Astrophysics Data System (ADS)
Bohm, Mirjam; Haberland, Christian; Asch, Günter
2013-04-01
We use local earthquake data observed by the amphibious, temporary seismic MERAMEX array to derive spatial variations of seismic attenuation (Qp) in the crust and upper mantle beneath Central Java. The path-averaged attenuation values (t∗) of a high quality subset of 84 local earthquakes were calculated by a spectral inversion technique. These 1929 t∗-values inverted by a least-squares tomographic inversion yield the 3D distribution of the specific attenuation (Qp). Analysis of the model resolution matrix and synthetic recovery tests were used to investigate the confidence of the Qp-model. We notice a prominent zone of increased attenuation beneath and north of the modern volcanic arc at depths down to 15 km. Most of this anomaly seems to be related to the Eocene-Miocene Kendeng Basin (mainly in the eastern part of the study area). Enhanced attenuation is also found in the upper crust in the direct vicinity of recent volcanoes pointing towards zones of partial melts, presence of fluids and increased temperatures in the middle to upper crust. The middle and lower crust seems not to be associated with strong heating and the presence of melts throughout the arc. Enhanced attenuation above the subducting slab beneath the marine forearc seems to be due to the presence of fluids.
Teklemariam, A.; Hodson-Tole, E. F.; Reeves, N. D.; Costen, N. P.; Cooper, G.
2016-01-01
Introduction Surface electromyography (sEMG) is the measurement of the electrical activity of the skeletal muscle tissue detected at the skin’s surface. Typically, a bipolar electrode configuration is used. Most muscles have pennate and/or curved fibres, meaning it is not always feasible to align the bipolar electrodes along the fibres direction. Hence, there is a need to explore how different electrode designs can affect sEMG measurements. Method A three layer finite element (skin, fat, muscle) muscle model was used to explore different electrode designs. The implemented model used as source signal an experimentally recorded intramuscular EMG taken from the biceps brachii muscle of one healthy male. A wavelet based intensity analysis of the simulated sEMG signal was performed to analyze the power of the signal in the time and frequency domain. Results The model showed muscle tissue causing a bandwidth reduction (to 20-92- Hz). The inter-electrode distance (IED) and the electrode orientation relative to the fibres affected the total power but not the frequency filtering response. The effect of significant misalignment between the electrodes and the fibres (60°- 90°) could be reduced by increasing the IED (25–30 mm), which attenuates signal cancellation. When modelling pennated fibres, the muscle tissue started to act as a low pass filter. The effect of different IED seems to be enhanced in the pennated model, while the filtering response is changed considerably only when the electrodes are close to the signal termination within the model. For pennation angle greater than 20°, more than 50% of the source signal was attenuated, which can be compensated by increasing the IED to 25 mm. Conclusion Differences in tissue filtering properties, shown in our model, indicates that different electrode designs should be considered for muscle with different geometric properties (i.e. pennated muscles). PMID:26886908
Teklemariam, A; Hodson-Tole, E F; Reeves, N D; Costen, N P; Cooper, G
2016-01-01
Surface electromyography (sEMG) is the measurement of the electrical activity of the skeletal muscle tissue detected at the skin's surface. Typically, a bipolar electrode configuration is used. Most muscles have pennate and/or curved fibres, meaning it is not always feasible to align the bipolar electrodes along the fibres direction. Hence, there is a need to explore how different electrode designs can affect sEMG measurements. A three layer finite element (skin, fat, muscle) muscle model was used to explore different electrode designs. The implemented model used as source signal an experimentally recorded intramuscular EMG taken from the biceps brachii muscle of one healthy male. A wavelet based intensity analysis of the simulated sEMG signal was performed to analyze the power of the signal in the time and frequency domain. The model showed muscle tissue causing a bandwidth reduction (to 20-92- Hz). The inter-electrode distance (IED) and the electrode orientation relative to the fibres affected the total power but not the frequency filtering response. The effect of significant misalignment between the electrodes and the fibres (60°-90°) could be reduced by increasing the IED (25-30 mm), which attenuates signal cancellation. When modelling pennated fibres, the muscle tissue started to act as a low pass filter. The effect of different IED seems to be enhanced in the pennated model, while the filtering response is changed considerably only when the electrodes are close to the signal termination within the model. For pennation angle greater than 20°, more than 50% of the source signal was attenuated, which can be compensated by increasing the IED to 25 mm. Differences in tissue filtering properties, shown in our model, indicates that different electrode designs should be considered for muscle with different geometric properties (i.e. pennated muscles).
A unifying fractional wave equation for compressional and shear waves.
Holm, Sverre; Sinkus, Ralph
2010-01-01
This study has been motivated by the observed difference in the range of the power-law attenuation exponent for compressional and shear waves. Usually compressional attenuation increases with frequency to a power between 1 and 2, while shear wave attenuation often is described with powers less than 1. Another motivation is the apparent lack of partial differential equations with desirable properties such as causality that describe such wave propagation. Starting with a constitutive equation which is a generalized Hooke's law with a loss term containing a fractional derivative, one can derive a causal fractional wave equation previously given by Caputo [Geophys J. R. Astron. Soc. 13, 529-539 (1967)] and Wismer [J. Acoust. Soc. Am. 120, 3493-3502 (2006)]. In the low omegatau (low-frequency) case, this equation has an attenuation with a power-law in the range from 1 to 2. This is consistent with, e.g., attenuation in tissue. In the often neglected high omegatau (high-frequency) case, it describes attenuation with a power-law between 0 and 1, consistent with what is observed in, e.g., dynamic elastography. Thus a unifying wave equation derived properly from constitutive equations can describe both cases.
Drummond, Sean P A; Anderson, Dane E; Straus, Laura D; Vogel, Edward K; Perez, Veronica B
2012-01-01
Sleep deprivation has adverse consequences for a variety of cognitive functions. The exact effects of sleep deprivation, though, are dependent upon the cognitive process examined. Within working memory, for example, some component processes are more vulnerable to sleep deprivation than others. Additionally, the differential impacts on cognition of different types of sleep deprivation have not been well studied. The aim of this study was to examine the effects of one night of total sleep deprivation and 4 nights of partial sleep deprivation (4 hours in bed/night) on two components of visual working memory: capacity and filtering efficiency. Forty-four healthy young adults were randomly assigned to one of the two sleep deprivation conditions. All participants were studied: 1) in a well-rested condition (following 6 nights of 9 hours in bed/night); and 2) following sleep deprivation, in a counter-balanced order. Visual working memory testing consisted of two related tasks. The first measured visual working memory capacity and the second measured the ability to ignore distractor stimuli in a visual scene (filtering efficiency). Results showed neither type of sleep deprivation reduced visual working memory capacity. Partial sleep deprivation also generally did not change filtering efficiency. Total sleep deprivation, on the other hand, did impair performance in the filtering task. These results suggest components of visual working memory are differentially vulnerable to the effects of sleep deprivation, and different types of sleep deprivation impact visual working memory to different degrees. Such findings have implications for operational settings where individuals may need to perform with inadequate sleep and whose jobs involve receiving an array of visual information and discriminating the relevant from the irrelevant prior to making decisions or taking actions (e.g., baggage screeners, air traffic controllers, military personnel, health care providers).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ma, C; Yu, L; Vrieze, T
Purpose: Added filtration such as tin filter has the potential to improve dose efficiency of x-ray beam in lung-cancer screening CT. However, dose efficiency with added beam filtration is highly dependent on patient attenuation level. In this phantom study, we evaluated the image quality at different tube voltages with and without added tin filter when attenuation level varies. Methods: A 30 x 20 cm anthropomorphic thorax phantom with three added extension rings were used to simulate small (S), medium (M), large (L), and extra-large (XL) adult patients. These phantoms were scanned on a 192-slice CT scanner (Force, Siemens) at 100more » and 120kV without tin filtration, and 100 and 150 kV with tin filtration (100Sn and 150Sn), at multiple dose levels at each kV. Images were reconstructed using iterative reconstruction (ADMIRE, Siemens). Radiation dose was measured with a 0.6 cc ion chamber in the middle and peripheral areas of the phantom. Image quality was assessed using mean image noise at uniform areas in the central region and lung. Radiation dose that is required for each kV to match the noise in a routine lung-cancer CT screening technique (120kV, 25 quality reference mAs) was calculated. Results: At each of the four phantom sizes, 100Sn had the lowest noise in both soft tissue and lung. Compared with 120 kV, 100Sn saved 39%–60% dose for the same noise, depending on phantom size. For the XL phantom (50 by 40 cm), 150Sn provided images with the least beam-hardening artifact in peripheral region. Conclusion: For thoracic CT, added tin filtration can provide considerable dose reduction compared with 120 kV. 100Sn provides better dose efficiencies for all phantom sizes, while 150Sn provides better image quality in peripheral region for extra-large patients. Drs.Joel G. Fletcher and Cynthia H. McCollough receive research support from Siemens Healthcare.« less
Potential for unreliable interpretation of EEG recorded with microelectrodes.
Stacey, William C; Kellis, Spencer; Greger, Bradley; Butson, Christopher R; Patel, Paras R; Assaf, Trevor; Mihaylova, Temenuzhka; Glynn, Simon
2013-08-01
Recent studies in epilepsy, cognition, and brain machine interfaces have shown the utility of recording intracranial electroencephalography (iEEG) with greater spatial resolution. Many of these studies utilize microelectrodes connected to specialized amplifiers that are optimized for such recordings. We recently measured the impedances of several commercial microelectrodes and demonstrated that they will distort iEEG signals if connected to clinical EEG amplifiers commonly used in most centers. In this study we demonstrate the clinical implications of this effect and identify some of the potential difficulties in using microelectrodes. Human iEEG data were digitally filtered to simulate the signal recorded by a hybrid grid (two macroelectrodes and eight microelectrodes) connected to a standard EEG amplifier. The filtered iEEG data were read by three trained epileptologists, and high frequency oscillations (HFOs) were detected with a well-known algorithm. The filtering method was verified experimentally by recording an injected EEG signal in a saline bath with the same physical acquisition system used to generate the model. Several electrodes underwent scanning electron microscopy (SEM). Macroelectrode recordings were unaltered compared to the source iEEG signal, but microelectrodes attenuated low frequencies. The attenuated signals were difficult to interpret: all three clinicians changed their clinical scoring of slowing and seizures when presented with the same data recorded on different sized electrodes. The HFO detection algorithm was oversensitive with microelectrodes, classifying many more HFOs than when the same data were recorded with macroelectrodes. In addition, during experimental recordings the microelectrodes produced much greater noise as well as large baseline fluctuations, creating sharply contoured transients, and superimposed "false" HFOs. SEM of these microelectrodes demonstrated marked variability in exposed electrode surface area, lead fractures, and sharp edges. Microelectrodes should not be used with low impedance (<1 GΩ) amplifiers due to severe signal attenuation and variability that changes clinical interpretations. The current method of preparing microelectrodes can leave sharp edges and nonuniform amounts of exposed wire. Even when recorded with higher impedance amplifiers, microelectrode data are highly prone to artifacts that are difficult to interpret. Great care must be taken when analyzing iEEG from high impedance microelectrodes. Wiley Periodicals, Inc. © 2013 International League Against Epilepsy.
Direct Reconstruction of CT-Based Attenuation Correction Images for PET With Cluster-Based Penalties
NASA Astrophysics Data System (ADS)
Kim, Soo Mee; Alessio, Adam M.; De Man, Bruno; Kinahan, Paul E.
2017-03-01
Extremely low-dose (LD) CT acquisitions used for PET attenuation correction have high levels of noise and potential bias artifacts due to photon starvation. This paper explores the use of a priori knowledge for iterative image reconstruction of the CT-based attenuation map. We investigate a maximum a posteriori framework with cluster-based multinomial penalty for direct iterative coordinate decent (dICD) reconstruction of the PET attenuation map. The objective function for direct iterative attenuation map reconstruction used a Poisson log-likelihood data fit term and evaluated two image penalty terms of spatial and mixture distributions. The spatial regularization is based on a quadratic penalty. For the mixture penalty, we assumed that the attenuation map may consist of four material clusters: air + background, lung, soft tissue, and bone. Using simulated noisy sinogram data, dICD reconstruction was performed with different strengths of the spatial and mixture penalties. The combined spatial and mixture penalties reduced the root mean squared error (RMSE) by roughly two times compared with a weighted least square and filtered backprojection reconstruction of CT images. The combined spatial and mixture penalties resulted in only slightly lower RMSE compared with a spatial quadratic penalty alone. For direct PET attenuation map reconstruction from ultra-LD CT acquisitions, the combination of spatial and mixture penalties offers regularization of both variance and bias and is a potential method to reconstruct attenuation maps with negligible patient dose. The presented results, using a best-case histogram suggest that the mixture penalty does not offer a substantive benefit over conventional quadratic regularization and diminishes enthusiasm for exploring future application of the mixture penalty.
NASA Technical Reports Server (NTRS)
Simon, M. K.
1981-01-01
This paper considers the performance of quadrature partial response (QPR) in the presence of jamming. Although a QPR system employs a single sample detector in its receiver, while quadrature amplitude shift keying (or quadrature phase shift keying) requires a matched-filter type of receiver, it is shown that the coherent detection performances of the two in the presence of the intentional jammer have definite similarities.
Linear Phase Sharp Transition BPF to Detect Noninvasive Maternal and Fetal Heart Rate.
Marchon, Niyan; Naik, Gourish; Pai, K R
2018-01-01
Fetal heart rate (FHR) detection can be monitored using either direct fetal scalp electrode recording (invasive) or by indirect noninvasive technique. Weeks before delivery, the invasive method poses a risk factor to the fetus, while the latter provides accurate fetal ECG (FECG) information which can help diagnose fetal's well-being. Our technique employs variable order linear phase sharp transition (LPST) FIR band-pass filter which shows improved stopband attenuation at higher filter orders. The fetal frequency fiduciary edges form the band edges of the filter characterized by varying amounts of overlap of maternal ECG (MECG) spectrum. The one with the minimum maternal spectrum overlap was found to be optimum with no power line interference and maximum fetal heart beats being detected. The improved filtering is reflected in the enhancement of the performance of the fetal QRS detector (FQRS). The improvement has also occurred in fetal heart rate obtained using our algorithm which is in close agreement with the true reference (i.e., invasive fetal scalp ECG). The performance parameters of the FQRS detector such as sensitivity (Se), positive predictive value (PPV), and accuracy (F 1 ) were found to improve even for lower filter order. The same technique was extended to evaluate maternal QRS detector (MQRS) and found to yield satisfactory maternal heart rate (MHR) results.
Neurotrophins, including nerve growth factor (NGF) partially mediate many features of allergic airways disease including airways resistance and inflammation. Antibody blockade of NGF attenuates airways resistance associated with the allergen-specific airways responses in mice. ...
Glick, S J; Hawkins, W G; King, M A; Penney, B C; Soares, E J; Byrne, C L
1992-01-01
The application of stationary restoration techniques to SPECT images assumes that the modulation transfer function (MTF) of the imaging system is shift invariant. It was hypothesized that using intrinsic attenuation correction (i.e., methods which explicitly invert the exponential radon transform) would yield a three-dimensional (3-D) MTF which varies less with position within the transverse slices than the combined conjugate view two-dimensional (2-D) MTF varies with depth. Thus the assumption of shift invariance would become less of an approximation for 3-D post- than for 2-D pre-reconstruction restoration filtering. SPECT acquisitions were obtained from point sources located at various positions in three differently shaped, water-filled phantoms. The data were reconstructed with intrinsic attenuation correction, and 3-D MTFs were calculated. Four different intrinsic attenuation correction methods were compared: (1) exponentially weighted backprojection, (2) a modified exponentially weighted backprojection as described by Tanaka et al. [Phys. Med. Biol. 29, 1489-1500 (1984)], (3) a Fourier domain technique as described by Bellini et al. [IEEE Trans. ASSP 27, 213-218 (1979)], and (4) the circular harmonic transform (CHT) method as described by Hawkins et al. [IEEE Trans. Med. Imag. 7, 135-148 (1988)]. The dependence of the 3-D MTF obtained with these methods, on point source location within an attenuator, and on shape of the attenuator, was studied. These 3-D MTFs were compared to: (1) those MTFs obtained with no attenuation correction, and (2) the depth dependence of the arithmetic mean combined conjugate view 2-D MTFs.(ABSTRACT TRUNCATED AT 250 WORDS)
Three-dimensional laser velocimeter simultaneity detector
NASA Technical Reports Server (NTRS)
Brown, James L. (Inventor)
1990-01-01
A three-dimensional laser Doppler velocimeter has laser optics for a first channel positioned to create a probe volume in space, and laser optics and for second and third channels, respectively, positioned to create entirely overlapping probe volumes in space. The probe volumes and overlap partially in space. The photodetector is positioned to receive light scattered by a particle present in the probe volume, while photodetectors and are positioned to receive light scattered by a particle present in the probe volume. The photodetector for the first channel is directly connected to provide a first channel analog signal to frequency measuring circuits. The first channel is therefore a primary channel for the system. Photodetectors and are respectively connected through a second channel analog signal attenuator to frequency measuring circuits and through a third channel analog signal attenuator to frequency measuring circuits. The second and third channels are secondary channels, with the second and third channels analog signal attenuators and controlled by the first channel measurement burst signal on line. The second and third channels analog signal attenuators and attenuate the second and third channels analog signals only when the measurement burst signal is false.
Chao, Dongman; Wang, Qinyu; Balboni, Gianfranco; Ding, Guanghong; Xia, Ying
2016-12-01
Perinatal hypoxic-ischemic (HI) brain injury results in death or profound long-term neurologic disability in both children and adults. However, there is no effective pharmacological therapy due to a poor understanding of HI events, especially the initial triggers for hypoxic-ischemic injury such as disrupted ionic homeostasis and the lack of effective intervention strategy. In the present study, we showed that neonatal brains undergo a developmental increase in the disruption of K + homeostasis during simulated ischemia, oxygen-glucose deprivation (OGD) and neonatal HI cortex has a triple phasic response (earlier attenuation, later enhancement, and then recovery) of disrupted K + homeostasis to OGD. This response partially involves the activity of the δ-opioid receptor (DOR) since the earlier attenuation of ischemic disruption of K + homeostasis could be blocked by DOR antagonism, while the later enhancement was reversed by DOR activation. Similar to DOR activation, acupuncture, a strategy to promote DOR activity, could partially reverse the later enhanced ischemic disruption of K + homeostasis in the neonatal cortex. Since maintaining cellular K + homeostasis and inhibiting excessive K + fluxes in the early phase of hypoxic-ischemic insults may be of therapeutic benefit in the treatment of ischemic brain injury and related neurodegenerative conditions, and since many neurons and other cells can be rescued during the "window of opportunity" after HI insults, our first findings regarding the role of acupuncture and DOR in attenuating ischemic disruption of K + homeostasis in the neonatal HI brain suggest a potential intervention therapy in the treatment of neonatal brain injury, especially hypoxic-ischemic encephalopathy.
Monte Carlo simulations for 20 MV X-ray spectrum reconstruction of a linear induction accelerator
NASA Astrophysics Data System (ADS)
Wang, Yi; Li, Qin; Jiang, Xiao-Guo
2012-09-01
To study the spectrum reconstruction of the 20 MV X-ray generated by the Dragon-I linear induction accelerator, the Monte Carlo method is applied to simulate the attenuations of the X-ray in the attenuators of different thicknesses and thus provide the transmission data. As is known, the spectrum estimation from transmission data is an ill-conditioned problem. The method based on iterative perturbations is employed to derive the X-ray spectra, where initial guesses are used to start the process. This algorithm takes into account not only the minimization of the differences between the measured and the calculated transmissions but also the smoothness feature of the spectrum function. In this work, various filter materials are put to use as the attenuator, and the condition for an accurate and robust solution of the X-ray spectrum calculation is demonstrated. The influences of the scattering photons within different intervals of emergence angle on the X-ray spectrum reconstruction are also analyzed.
Measurement of the attenuation length of argon scintillation light in the ArDM LAr TPC
NASA Astrophysics Data System (ADS)
Calvo, J.; Cantini, C.; Crivelli, P.; Daniel, M.; Di Luise, S.; Gendotti, A.; Horikawa, S.; Molina-Bueno, L.; Montes, B.; Mu, W.; Murphy, S.; Natterer, G.; Nguyen, K.; Periale, L.; Quan, Y.; Radics, B.; Regenfus, C.; Romero, L.; Rubbia, A.; Santorelli, R.; Sergiampietri, F.; Viant, T.; Wu, S.
2018-01-01
We report on a measurement of the attenuation length for the scintillation light in the tonne size liquid argon target of the ArDM dark matter experiment. The data was recorded in the first underground operation of the experiment in single-phase operational mode. The results were achieved by comparing the light yield spectra from 39Ar and 83mKr to a description of the ArDM setup with a model of full light ray tracing. A relatively low value close to 0.5 m was found for the attenuation length of the liquid argon bulk to its own scintillation light. We interpret this result as a presence of optically active impurities in the liquid argon which are not filtered by the installed purification systems. We also present analyses of the argon gas employed for the filling and discuss cross sections in the vacuum ultraviolet of various molecules in respect to purity requirements in the context of large liquid argon installations.
Park, Minkyu; Anumol, Tarun; Daniels, Kevin D; Wu, Shimin; Ziska, Austin D; Snyder, Shane A
2017-08-01
Ozone oxidation has been demonstrated to be an effective treatment process for the attenuation of trace organic compounds (TOrCs); however, predicting TOrC attenuation by ozone processes is challenging in wastewaters. Since ozone is rapidly consumed, determining the exposure times of ozone and hydroxyl radical proves to be difficult. As direct potable reuse schemes continue to gain traction, there is an increasing need for the development of real-time monitoring strategies for TOrC abatement in ozone oxidation processes. Hence, this study is primarily aimed at developing indicator and surrogate models for the prediction of TOrC attenuation by ozone oxidation. To this end, the second-order kinetic equations with a second-phase R ct value (ratio of hydroxyl radical exposure to molecular ozone exposure) were used to calculate comparative kinetics of TOrC attenuation and the reduction of indicator and spectroscopic surrogate parameters, including UV absorbance at 254 nm (UVA 254 ) and total fluorescence (TF). The developed indicator model using meprobamate as an indicator compound and the surrogate models with UVA 254 and TF exhibited good predictive power for the attenuation of 13 kinetically distinct TOrCs in five filtered and unfiltered wastewater effluents (R 2 values > 0.8). This study is intended to help provide a guideline for the implementation of indicator/surrogate models for real-time monitoring of TOrC abatement with ozone processes and integrate them into a regulatory framework in water reuse. Copyright © 2017 Elsevier Ltd. All rights reserved.
Stable time filtering of strongly unstable spatially extended systems
Grote, Marcus J.; Majda, Andrew J.
2006-01-01
Many contemporary problems in science involve making predictions based on partial observation of extremely complicated spatially extended systems with many degrees of freedom and with physical instabilities on both large and small scale. Various new ensemble filtering strategies have been developed recently for these applications, and new mathematical issues arise. Because ensembles are extremely expensive to generate, one such issue is whether it is possible under appropriate circumstances to take long time steps in an explicit difference scheme and violate the classical Courant–Friedrichs–Lewy (CFL)-stability condition yet obtain stable accurate filtering by using the observations. These issues are explored here both through elementary mathematical theory, which provides simple guidelines, and the detailed study of a prototype model. The prototype model involves an unstable finite difference scheme for a convection–diffusion equation, and it is demonstrated below that appropriate observations can result in stable accurate filtering of this strongly unstable spatially extended system. PMID:16682626
Stable time filtering of strongly unstable spatially extended systems.
Grote, Marcus J; Majda, Andrew J
2006-05-16
Many contemporary problems in science involve making predictions based on partial observation of extremely complicated spatially extended systems with many degrees of freedom and with physical instabilities on both large and small scale. Various new ensemble filtering strategies have been developed recently for these applications, and new mathematical issues arise. Because ensembles are extremely expensive to generate, one such issue is whether it is possible under appropriate circumstances to take long time steps in an explicit difference scheme and violate the classical Courant-Friedrichs-Lewy (CFL)-stability condition yet obtain stable accurate filtering by using the observations. These issues are explored here both through elementary mathematical theory, which provides simple guidelines, and the detailed study of a prototype model. The prototype model involves an unstable finite difference scheme for a convection-diffusion equation, and it is demonstrated below that appropriate observations can result in stable accurate filtering of this strongly unstable spatially extended system.
Tracking and people counting using Particle Filter Method
NASA Astrophysics Data System (ADS)
Sulistyaningrum, D. R.; Setiyono, B.; Rizky, M. S.
2018-03-01
In recent years, technology has developed quite rapidly, especially in the field of object tracking. Moreover, if the object under study is a person and the number of people a lot. The purpose of this research is to apply Particle Filter method for tracking and counting people in certain area. Tracking people will be rather difficult if there are some obstacles, one of which is occlusion. The stages of tracking and people counting scheme in this study include pre-processing, segmentation using Gaussian Mixture Model (GMM), tracking using particle filter, and counting based on centroid. The Particle Filter method uses the estimated motion included in the model used. The test results show that the tracking and people counting can be done well with an average accuracy of 89.33% and 77.33% respectively from six videos test data. In the process of tracking people, the results are good if there is partial occlusion and no occlusion
Characterization of a spectroscopic detector for application in x-ray computed tomography
NASA Astrophysics Data System (ADS)
Dooraghi, Alex A.; Fix, Brian J.; Smith, Jerel A.; Brown, William D.; Azevedo, Stephen G.; Martz, Harry E.
2017-09-01
Recent advances in cadmium telluride (CdTe) energy-discriminating pixelated detectors have enabled the possibility of Multi-Spectral X-ray Computed Tomography (MSXCT) to incorporate spectroscopic information into CT. MultiX ME 100 V2 is a CdTe-based spectroscopic x-ray detector array capable of recording energies from 20 to 160 keV in 1.1 keV energy bin increments. Hardware and software have been designed to perform radiographic and computed tomography tasks with this spectroscopic detector. Energy calibration is examined using the end-point energy of a bremsstrahlung spectrum and radioisotope spectral lines. When measuring the spectrum from Am-241 across 500 detector elements, the standard deviation of the peak-location and FWHM measurements are +/- 0.4 and +/- 0.6 keV, respectively. As these values are within the energy bin size (1.1 keV), detector elements are consistent with each other. The count rate is characterized, using a nonparalyzable model with a dead time of 64 +/- 5 ns. This is consistent with the manufacturer's quoted per detector-element linear-deviation at 2 Mpps (million photons per sec) of 8.9 % (typical) and 12 % (max). When comparing measured and simulated spectra, a low-energy tail is visible in the measured data due to the spectral response of the detector. If no valid photon detections are expected in the low-energy tail, then a background subtraction may be applied to allow for a possible first-order correction. If photons are expected in the low-energy tail, a detailed model must be implemented. A radiograph of an aluminum step wedge with a maximum height of 20 mm shows an underestimation of attenuation by about 10 % at 60 keV. This error is due to partial energy deposition from higher energy (>60 keV) photons into a lower-energy ( 60 keV) bin, reducing the apparent attenuation. A radiograph of a polytetrafluoroethylene (PTFE) cylinder taken using a bremsstrahlung spectrum from an x-ray voltage of 100 kV filtered by 1.3 mm Cu is reconstructed using Abel inversion. As no counts are expected in the low energy tail, a first order background correction is applied to the spectrum. The measured linear attenuation coefficient (LAC) is within 10% of the expected value in the 60 to 100 keV range. Below 60 keV, low counts in the corrected spectrum and partial energy deposition from incident photons of energy greater than 60 keV into energy bins below 60 keV impact the LAC measurements. This report ends with a demonstration of the tomographic capability of the system. The quantitative understanding of the detector developed in this report will enable further study in evaluating the system for characterization of an object's chemical make-up for industrial and security purposes.
Characterization of a spectroscopic detector for application in x-ray computed tomography
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dooraghi, A. A.; Fix, B. J.; Smith, J. A.
Recent advances in cadmium telluride (CdTe) energy-discriminating pixelated detectors have enabled the possibility of Multi-Spectral X-ray Computed Tomography (MSXCT) to incorporate spectroscopic information into CT. MultiX ME 100 V2 is a CdTe-based spectroscopic x-ray detector array capable of recording energies from 20 to 160 keV in 1.1 keV energy bin increments. Hardware and software have been designed to perform radiographic and computed tomography tasks with this spectroscopic detector. Energy calibration is examined using the end-point energy of a bremsstrahlung spectrum and radioisotope spectral lines. When measuring the spectrum from Am-241 across 500 detector elements, the standard deviation of the peak-locationmore » and FWHM measurements are ±0.4 and ±0.6 keV, respectively. As these values are within the energy bin size (1.1 keV), detector elements are consistent with each other. The count rate is characterized, using a nonparalyzable model with a dead time of 64 ± 5 ns. This is consistent with the manufacturer’s quoted per detector-element linear-deviation at 2 Mpps (million photons per sec) of 8.9% (typical) and 12% (max). When comparing measured and simulated spectra, a low-energy tail is visible in the measured data due to the spectral response of the detector. If no valid photon detections are expected in the low-energy tail, then a background subtraction may be applied to allow for a possible first-order correction. If photons are expected in the low-energy tail, a detailed model must be implemented. A radiograph of an aluminum step wedge with a maximum height of about 20 mm shows an underestimation of attenuation by about 10% at 60 keV. This error is due to partial energy deposition from higher-energy (> 60 keV) photons into a lower-energy (~60 keV) bin, reducing the apparent attenuation. A radiograph of a PTFE cylinder taken using a bremsstrahlung spectrum from an x-ray voltage of 100 kV filtered by 1.3 mm Cu is reconstructed using Abel inversion. As no counts are expected in the low energy tail, a first order background correction is applied to the spectrum. The measured linear attenuation coefficient (LAC) is within 10% of the expected value in the 60 to 100 keV range. Below 60 keV, low counts in the corrected spectrum and partial energy deposition from incident photons of energy greater than 60 keV into energy bins below 60 keV impact the LAC measurements. This report ends with a demonstration of the tomographic capability of the system. The quantitative understanding of the detector developed in this report will enable further study in evaluating the system for characterization of an object’s chemical make-up for industrial and security purposes.« less
Synthesis and biological evaluation of manzamine analogues.
Winkler, Jeffrey D; Londregan, Allyn T; Ragains, Justin R; Hamann, Mark T
2006-07-20
[Structure: see text] The synthesis and biological evaluation of a series of analogues of manzamine A, representing partial structures of the pentacyclic ABCDE diamine core, is described. All new compounds were screened against Plasmodium falciparum and demonstrated attenuated antimalarial activity relative to that of manzamine A.
Supersonic flow with feeding of energy
NASA Technical Reports Server (NTRS)
Zaremba, W.
1985-01-01
The present work discusses the results of some experimental studies on the possibility of attenuating shock waves in a supersonic flow. The shock waves were formed by an external source of electrical energy. An electromechanical method is described that permits partial recovery of the expended energy.
Pollastro, R.M.
1982-01-01
Extremely well-oriented clay mineral mounts for X-ray diffraction analysis can be prepared quickly and without introducing segregation using the filter-membrane peel technique. Mounting problems encountered with smectite-rich samples can be resolved by using minimal sample and partial air-drying of the clay film before transfer to a glass slide. Samples containing small quantities of clay can produce useful oriented specimens if Teflon masks having more restrictive areas are inserted above the membrane filter during clay deposition. War]page and thermal shock of glass slides can be controlled by using a flat, porous, ceramic plate as a holding surface during heat treatments.
Deconvolution of time series in the laboratory
NASA Astrophysics Data System (ADS)
John, Thomas; Pietschmann, Dirk; Becker, Volker; Wagner, Christian
2016-10-01
In this study, we present two practical applications of the deconvolution of time series in Fourier space. First, we reconstruct a filtered input signal of sound cards that has been heavily distorted by a built-in high-pass filter using a software approach. Using deconvolution, we can partially bypass the filter and extend the dynamic frequency range by two orders of magnitude. Second, we construct required input signals for a mechanical shaker in order to obtain arbitrary acceleration waveforms, referred to as feedforward control. For both situations, experimental and theoretical approaches are discussed to determine the system-dependent frequency response. Moreover, for the shaker, we propose a simple feedback loop as an extension to the feedforward control in order to handle nonlinearities of the system.
Metzger, Stefan; Burba, George; Burns, Sean P.; ...
2016-03-31
Several initiatives are currently emerging to observe the exchange of energy and matter between the earth's surface and atmosphere standardized over larger space and time domains. For example, the National Ecological Observatory Network (NEON) and the Integrated Carbon Observing System (ICOS) are set to provide the ability of unbiased ecological inference across ecoclimatic zones and decades by deploying highly scalable and robust instruments and data processing. In the construction of these observatories, enclosed infrared gas analyzers are widely employed for eddy covariance applications. While these sensors represent a substantial improvement compared to their open- and closed-path predecessors, remaining high-frequency attenuation variesmore » with site properties and gas sampling systems, and requires correction. Here, we show that components of the gas sampling system can substantially contribute to such high-frequency attenuation, but their effects can be significantly reduced by careful system design. From laboratory tests we determine the frequency at which signal attenuation reaches 50 % for individual parts of the gas sampling system. For different models of rain caps and particulate filters, this frequency falls into ranges of 2.5–16.5 Hz for CO 2, 2.4–14.3 Hz for H 2O, and 8.3–21.8 Hz for CO 2, 1.4–19.9 Hz for H 2O, respectively. A short and thin stainless steel intake tube was found to not limit frequency response, with 50 % attenuation occurring at frequencies well above 10 Hz for both H 2O and CO 2. From field tests we found that heating the intake tube and particulate filter continuously with 4 W was effective, and reduced the occurrence of problematic relative humidity levels (RH > 60 %) by 50 % in the infrared gas analyzer cell. No further improvement of H 2O frequency response was found for heating in excess of 4 W. These laboratory and field tests were reconciled using resistor–capacitor theory, and NEON's final gas sampling system was developed on this basis. The design consists of the stainless steel intake tube, a pleated mesh particulate filter and a low-volume rain cap in combination with 4 W of heating and insulation. In comparison to the original design, this reduced the high-frequency attenuation for H 2O by ≈ 3/4, and the remaining cospectral correction did not exceed 3 %, even at high relative humidity (95 %). The standardized design can be used across a wide range of ecoclimates and site layouts, and maximizes practicability due to minimal flow resistance and maintenance needs. Lastly, due to minimal high-frequency spectral loss, it supports the routine application of adaptive correction procedures, and enables largely automated data processing across sites.« less
Sheng, Kaixuan; Sun, Yiqing; Li, Chun; Yuan, Wenjing; Shi, Gaoquan
2012-01-01
The recent boom in multifunction portable electronic equipments requires the development of compact and miniaturized electronic circuits with high efficiencies, low costs and long lasting time. For the operation of most line-powered electronics, alternating current (ac) line-filters are used to attenuate the leftover ac ripples on direct current (dc) voltage busses. Today, aluminum electrolytic capacitors (AECs) are widely applied for this purpose. However, they are usually the largest components in electronic circuits. Replacing AECs by more compact capacitors will have an immense impact on future electronic devices. Here, we report a double-layer capacitor based on three-dimensional (3D) interpenetrating graphene electrodes fabricated by electrochemical reduction of graphene oxide (ErGO-DLC). At 120-hertz, the ErGO-DLC exhibited a phase angle of -84 degrees, a specific capacitance of 283 microfaradays per centimeter square and a resistor-capacitor (RC) time constant of 1.35 milliseconds, making it capable of replacing AECs for the application of 120-hertz filtering.
NASA Astrophysics Data System (ADS)
Sheng, Kaixuan; Sun, Yiqing; Li, Chun; Yuan, Wenjing; Shi, Gaoquan
2012-02-01
The recent boom in multifunction portable electronic equipments requires the development of compact and miniaturized electronic circuits with high efficiencies, low costs and long lasting time. For the operation of most line-powered electronics, alternating current (ac) line-filters are used to attenuate the leftover ac ripples on direct current (dc) voltage busses. Today, aluminum electrolytic capacitors (AECs) are widely applied for this purpose. However, they are usually the largest components in electronic circuits. Replacing AECs by more compact capacitors will have an immense impact on future electronic devices. Here, we report a double-layer capacitor based on three-dimensional (3D) interpenetrating graphene electrodes fabricated by electrochemical reduction of graphene oxide (ErGO-DLC). At 120-hertz, the ErGO-DLC exhibited a phase angle of -84 degrees, a specific capacitance of 283 microfaradays per centimeter square and a resistor-capacitor (RC) time constant of 1.35 milliseconds, making it capable of replacing AECs for the application of 120-hertz filtering.
Sheng, Kaixuan; Sun, Yiqing; Li, Chun; Yuan, Wenjing; Shi, Gaoquan
2012-01-01
The recent boom in multifunction portable electronic equipments requires the development of compact and miniaturized electronic circuits with high efficiencies, low costs and long lasting time. For the operation of most line-powered electronics, alternating current (ac) line-filters are used to attenuate the leftover ac ripples on direct current (dc) voltage busses. Today, aluminum electrolytic capacitors (AECs) are widely applied for this purpose. However, they are usually the largest components in electronic circuits. Replacing AECs by more compact capacitors will have an immense impact on future electronic devices. Here, we report a double-layer capacitor based on three-dimensional (3D) interpenetrating graphene electrodes fabricated by electrochemical reduction of graphene oxide (ErGO-DLC). At 120-hertz, the ErGO-DLC exhibited a phase angle of −84 degrees, a specific capacitance of 283 microfaradays per centimeter square and a resistor-capacitor (RC) time constant of 1.35 milliseconds, making it capable of replacing AECs for the application of 120-hertz filtering. PMID:22355759
Adaptive spatial filtering using photochromic glass
NASA Astrophysics Data System (ADS)
Potton, R. J.
1999-12-01
Commercially available photochromic glasses exhibit a wide range of spectral sensitivities and darkening response times. Short wavelengths are more effective than long ones for causing darkening but at least one type of glass is effectively darkened by red light (icons/Journals/Common/lambda" ALT="lambda" ALIGN="TOP"/> = 633 nm) with an intensity of about 1 kW m-2. Used as adaptive spatial filters, these glasses attenuate a wavefront by an amount that depends on their recent exposure to light. One type of optical processing that can be performed with such filters is drift nulling in an interferometer excited by light of a wavelength within the sensitivity spectrum of the photochrome. This form of processing has been demonstrated by dithering the speckle pattern in a single-fibre multimode interferometer. The dither allows phase-sensitive detection techniques to be used in the detection of signal-induced phase variations in a frequency band extending from the inverse response time of the photochrome to the dither frequency.
High-frequency filtering of strong-motion records
Douglas, J.; Boore, D.M.
2011-01-01
The influence of noise in strong-motion records is most problematic at low and high frequencies where the signal to noise ratio is commonly low compared to that in the mid-spectrum. The impact of low-frequency noise (5 Hz) on computed pseudo-absolute response spectral accelerations (PSAs). In contrast to the case of low-frequency noise our analysis shows that filtering to remove high-frequency noise is only necessary in certain situations and that PSAs can often be used up to 100 Hz even if much lower high-cut corner frequencies are required to remove the noise. This apparent contradiction can be explained by the fact that PSAs are often controlled by ground accelerations associated with much lower frequencies than the natural frequency of the oscillator because path and site attenuation (often modelled by Q and κ, respectively) have removed the highest frequencies. We demonstrate that if high-cut filters are to be used, then their corner frequencies should be selected on an individual basis, as has been done in a few recent studies.
NASA Astrophysics Data System (ADS)
Gan, Shuwei; Wang, Shoudong; Chen, Yangkang; Chen, Xiaohong; Xiang, Kui
2016-01-01
Simultaneous-source shooting can help tremendously shorten the acquisition period and improve the quality of seismic data for better subsalt seismic imaging, but at the expense of introducing strong interference (blending noise) to the acquired seismic data. We propose to use a structural-oriented median filter to attenuate the blending noise along the structural direction of seismic profiles. The principle of the proposed approach is to first flatten the seismic record in local spatial windows and then to apply a traditional median filter (MF) to the third flattened dimension. The key component of the proposed approach is the estimation of the local slope, which can be calculated by first scanning the NMO velocity and then transferring the velocity to the local slope. Both synthetic and field data examples show that the proposed approach can successfully separate the simultaneous-source data into individual sources. We provide an open-source toy example to better demonstratethe proposed methodology.
Relationship of strength of turbulence to received power
NASA Technical Reports Server (NTRS)
Rottger, J.
1983-01-01
Because of contributions due to reflection, the determination of the turbulence refractive index structure constant may be affected. For pure scattering from turbulence in the inertial subrange, the radar echo power can be used to calculate the refractive index structure constant. The radar power is determined by a convolution integral. If the antenna beam is swung to sufficiently large off-zenith angles ( 12.5 deg) so that a quasi-isotropic response from the tail ends of the Gaussian angular distribution can be anticipated, the evaluation of the convolution integral depends only on the known antenna pattern of the radar. This procedure, swinging the radar beam to attenuate the reflected component, may be called angular or direction filtering. The tilted antenna also may be pick up reflected components from near the zenith through the sidelobes. This can be tested by the evaluation of the correlation function. This method applies a time domain filtering of the intensity time series but needs a very careful selection of the high pass filters.
NASA Astrophysics Data System (ADS)
Fountaine, Katherine T.; Ito, Mikinori; Pala, Ragip; Atwater, Harry A.
2016-09-01
Spectrally-selective nanophotonic and plasmonic structures enjoy widespread interest for application as color filters in imaging devices, due to their potential advantages over traditional organic dyes and pigments. Organic dyes are straightforward to implement with predictable optical performance at large pixel size, but suffer from inherent optical cross-talk and stability (UV, thermal, humidity) issues and also exhibit increasingly unpredictable performance as pixel size approaches dye molecule size. Nanophotonic and plasmonic color filters are more robust, but often have polarization- and angle-dependent optical response and/or require large-range periodicity. Herein, we report on design and fabrication of polarization- and angle-insensitive CYM color filters based on a-Si nanopillar arrays as small as 1um2, supported by experiment, simulation, and analytic theory. Analytic waveguide and Mie theories explain the color filtering mechanism- efficient coupling into and interband transition-mediated attenuation of waveguide-like modes—and also guided the FDTD simulation-based optimization of nanopillar array dimensions. The designed a-Si nanopillar arrays were fabricated using e-beam lithography and reactive ion etching; and were subsequently optically characterized, revealing the predicted polarization- and angle-insensitive (±40°) subtractive filter responses. Cyan, yellow, and magenta color filters have each been demonstrated. The effects of nanopillar array size and inter-array spacing were investigated both experimentally and theoretically to probe the issues of ever-shrinking pixel sizes and cross-talk, respectively. Results demonstrate that these nanopillar arrays maintain their performance down to 1um2 pixel sizes with no inter-array spacing. These concepts and results along with color-processed images taken with a fabricated color filter array will be presented and discussed.
Acceptance Testing of Thermoluminescent Dosimeter Holders.
Romanyukha, Alexander; Grypp, Matthew D; Sharp, Thad J; DiRito, John N; Nelson, Martin E; Mavrogianis, Stanley T; Torres, Jeancarlo; Benevides, Luis A
2018-05-01
The U.S. Navy uses the Harshaw 8840/8841 dosimetric (DT-702/PD) system, which employs LiF:Mg,Cu,P thermoluminescent dosimeters (TLDs), developed and produced by Thermo Fisher Scientific (TFS). The dosimeter consists of four LiF:Mg,Cu,P elements, mounted in Teflon® on an aluminum card and placed in a plastic holder. The holder contains a unique filter for each chip made of copper, acrylonitrile butadiene styrene (ABS), Mylar®, and tin. For accredited dosimetry labs, the ISO/IEC 17025:2005(E) requires an acceptance procedure for all new equipment. The Naval Dosimetry Center (NDC) has developed and tested a new non-destructive procedure, which enables the verification and the evaluation of embedded filters in the holders. Testing is based on attenuation measurements of low-energy radiation transmitted through each filter in a representative sample group of holders to verify that the correct filter type and thickness are present. The measured response ratios are then compared with the expected response ratios. In addition, each element's measured response is compared to the mean response of the group. The test was designed and tested to identify significant nonconformities, such as missing copper or tin filters, double copper or double tin filters, or other nonconformities that may impact TLD response ratios. During the implementation of the developed procedure, testing revealed a holder with a double copper filter. To complete the evaluation, the impact of the nonconformities on proficiency testing was examined. The evaluation revealed failures in proficiency testing categories III and IV when these dosimeters were irradiated to high-energy betas.
Two concepts of phototropic systems application are presented in this report. These concepts, when considered individually or in combination, make...possible the development of improved, directly or indirectly actuated, phototropic , ophthalmic, nuclear flash-protective devices. By the application...of a phototropic filter at the focal plane of an optical system, the attenuation of the phototropic response due to distance is minimized. Using a
Integrated Photonic Orbital Angular Momentum Multiplexing and Demultiplexing on Chip
2014-10-31
OAM free space coherent communication link testbed. ECL: external cavity laser . EDFA: erbium-doped fiber amplifier. PC: polarization controller. ATT...wave (cw) laser centered at 1540 nm, followed by an erbium-doped fiber amplifier (EDFA), an I/Q modulator, and another EDFA. The I/Q modulator was...communication link testbed. ECL: external cavity laser . EDFA: erbium-doped fiber amplifier. PC: polarization controller. ATT: attenuator. BPF: bandpass filter
W. J. Massman
2001-01-01
First, my thanks to Dr. Ullar Rannik for his interest and insights in my recent study of spectral corrections and associated eddy covariance flux loss (Massman, 2000, henceforth denoted by M2000). His comments are important and germane to the attenuation of low frequencies of the turbulent cospectra due to recursive filtering and block averaging. Dr. Rannik addresses...
Adaptive Control for Uncertain Nonlinear Multi-Input Multi-Output Systems
NASA Technical Reports Server (NTRS)
Cao, Chengyu (Inventor); Hovakimyan, Naira (Inventor); Xargay, Enric (Inventor)
2014-01-01
Systems and methods of adaptive control for uncertain nonlinear multi-input multi-output systems in the presence of significant unmatched uncertainty with assured performance are provided. The need for gain-scheduling is eliminated through the use of bandwidth-limited (low-pass) filtering in the control channel, which appropriately attenuates the high frequencies typically appearing in fast adaptation situations and preserves the robustness margins in the presence of fast adaptation.
Hybrid photonic signal processing
NASA Astrophysics Data System (ADS)
Ghauri, Farzan Naseer
This thesis proposes research of novel hybrid photonic signal processing systems in the areas of optical communications, test and measurement, RF signal processing and extreme environment optical sensors. It will be shown that use of innovative hybrid techniques allows design of photonic signal processing systems with superior performance parameters and enhanced capabilities. These applications can be divided into domains of analog-digital hybrid signal processing applications and free-space---fiber-coupled hybrid optical sensors. The analog-digital hybrid signal processing applications include a high-performance analog-digital hybrid MEMS variable optical attenuator that can simultaneously provide high dynamic range as well as high resolution attenuation controls; an analog-digital hybrid MEMS beam profiler that allows high-power watt-level laser beam profiling and also provides both submicron-level high resolution and wide area profiling coverage; and all optical transversal RF filters that operate on the principle of broadband optical spectral control using MEMS and/or Acousto-Optic tunable Filters (AOTF) devices which can provide continuous, digital or hybrid signal time delay and weight selection. The hybrid optical sensors presented in the thesis are extreme environment pressure sensors and dual temperature-pressure sensors. The sensors employ hybrid free-space and fiber-coupled techniques for remotely monitoring a system under simultaneous extremely high temperatures and pressures.
Modeling Flow Past a Tilted Vena Cava Filter
DOE Office of Scientific and Technical Information (OSTI.GOV)
Singer, M A; Wang, S L
Inferior vena cava filters are medical devices used to prevent pulmonary embolism (PE) from deep vein thrombosis. In particular, retrievable filters are well-suited for patients who are unresponsive to anticoagulation therapy and whose risk of PE decreased with time. The goal of this work is to use computational fluid dynamics to evaluate the flow past an unoccluded and partially occluded Celect inferior vena cava filter. In particular, the hemodynamic response to thrombus volume and filter tilt is examined, and the results are compared with flow conditions that are known to be thrombogenic. A computer model of the filter inside amore » model vena cava is constructed using high resolution digital photographs and methods of computer aided design. The models are parameterized using the Overture software framework, and a collection of overlapping grids is constructed to discretize the flow domain. The incompressible Navier-Stokes equations are solved, and the characteristics of the flow (i.e., velocity contours and wall shear stresses) are computed. The volume of stagnant and recirculating flow increases with thrombus volume. In addition, as the filter increases tilt, the cava wall adjacent to the tilted filter is subjected to low velocity flow that gives rise to regions of low wall shear stress. The results demonstrate the ease of IVC filter modeling with the Overture software framework. Flow conditions caused by the tilted Celect filter may elevate the risk of intrafilter thrombosis and facilitate vascular remodeling. This latter condition also increases the risk of penetration and potential incorporation of the hook of the filter into the vena caval wall, thereby complicating filter retrieval. Consequently, severe tilt at the time of filter deployment may warrant early clinical intervention.« less
Comparison of ion coupling strategies for a microengineered quadrupole mass filter.
Wright, Steven; Syms, Richard R A; O'Prey, Shane; Hong, Guodong; Holmes, Andrew S
2009-01-01
The limitations of conventional machining and assembly techniques require that designs for quadrupole mass analyzers with rod diameters less than a millimeter are not merely scale versions of larger instruments. We show how silicon planar processing techniques and microelectromechanical systems (MEMS) design concepts can be used to incorporate complex features into the construction of a miniature quadrupole mass filter chip that could not easily be achieved using other microengineering approaches. Three designs for the entrance and exit to the filter consistent with the chosen materials and techniques have been evaluated. The differences between these seemingly similar structures have a significant effect on the performance. Although one of the designs results in severe attenuation of transmission with increasing mass, the other two can be scanned to m/z = 400 without any corruption of the mass spectrum. At m/z = 219, the variation in the transmission of the three designs was found to be approximately four orders of magnitude. A maximum resolution of M/DeltaM = 87 at 10% peak height has been achieved at m/z = 219 with a filter operated at 6 MHz and constructed using rods measuring (508 +/- 5) microm in diameter.
A 128-Tap Highly Tunable CMOS IF Finite Impulse Response Filter for Pulsed Radar Applications
Mincey, John Stephen; Su, Eric C.; Silva-Martinez, Jose; ...
2018-02-28
A configurable-bandwidth (BW) filter is presented in this paper for pulsed radar applications. Also, to eliminate dispersion effects in the received waveform, a finite impulse response (FIR) topology is proposed, which has a measured standard deviation of an in-band group delay of 11 ns that is primarily dominated by the inherent, fully predictable delay introduced by the sample-and-hold. The filter operates at an IF of 20 MHz, and is tunable in BW from 1.5 to 15 MHz, which makes it optimal to be used with varying pulse widths in the radar. Employing a total of 128 taps, the FIR filtermore » provides greater than 50-dB sharp attenuation in the stopband in order to minimize all out-of-band noise in the low signal-to-noise received radar signal. Fabricated in a 0.18-μm silicon on insulator CMOS process, the proposed filter consumes approximately 3.5 mW/tap with a 1.8-V supply. Finally, a 20-MHz two-tone measurement with 200-kHz tone separation shows IIP3 greater than 8.5 dBm.« less
A 128-Tap Highly Tunable CMOS IF Finite Impulse Response Filter for Pulsed Radar Applications
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mincey, John Stephen; Su, Eric C.; Silva-Martinez, Jose
A configurable-bandwidth (BW) filter is presented in this paper for pulsed radar applications. Also, to eliminate dispersion effects in the received waveform, a finite impulse response (FIR) topology is proposed, which has a measured standard deviation of an in-band group delay of 11 ns that is primarily dominated by the inherent, fully predictable delay introduced by the sample-and-hold. The filter operates at an IF of 20 MHz, and is tunable in BW from 1.5 to 15 MHz, which makes it optimal to be used with varying pulse widths in the radar. Employing a total of 128 taps, the FIR filtermore » provides greater than 50-dB sharp attenuation in the stopband in order to minimize all out-of-band noise in the low signal-to-noise received radar signal. Fabricated in a 0.18-μm silicon on insulator CMOS process, the proposed filter consumes approximately 3.5 mW/tap with a 1.8-V supply. Finally, a 20-MHz two-tone measurement with 200-kHz tone separation shows IIP3 greater than 8.5 dBm.« less
First evidence for high anelastic attenuation beneath the Red Sea from Love wave analysis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hadiouche, Ouiza
Attenuation coefficients of Love waves are determined for two seismic paths along the Red Sea. The attenuation coefficients are obtained using the multiple filter method for periods from 25 to 130 s along one path and from 40 to 130 s along the second one. The two sets of observations are in good agreement with anomalously high attenuation coefficients similar to those reported across a young part of the Pacific Ocean. Indeed, the values lie on average between 3.3 {plus minus} 0.6 and 1.1 {plus minus} 0.3 (10{sup {minus}4}km{sup {minus}1}) higher values being observed at shorter periods. In a secondmore » part of the paper, these apparent attenuation observations are interpreted in terms of a distribution of intrinsic absorption in the upper mantle. A frequency independent Q{sub {beta}} model is obtained using a trial-and-error method. The best fit to the data required a large and very low Q{sub {beta}} (30-50) zone below a depth of 50 km, underlying a thin and high Q{sub {beta}} (200-300) lid. These results are consistent with high heat flows and low velocities which characterize this tectonically active area, and corroborate the inference of anomalously high temperatures and low viscosity in the upper mantle beneath the Red Sea from recent seismological results.« less
Falatko, John M; Dalal, Bhavinkumar; Qu, Lihua
2017-12-01
Anticoagulation is the primary treatment for pulmonary embolism (PE). Inferior vena cava (IVC) filters are an adjunctive intervention to prevent recurrent pulmonary embolism. Long-term outcomes in elderly patients with contraindications to anticoagulation after IVC filter placement for prevention of recurrent pulmonary embolism have yet to be assessed. Patients ≥60years of age, that had an IVC filter placed between 1 January, 2008 and 2 February, 2013, with a primary diagnosis of pulmonary embolism, were included. Patients that died during index hospitalisation, were discharged to hospice, or had active malignancy were excluded. The primary endpoint was overall survival. Patients were divided depending on whether they were treated with an approved anticoagulant for VTE or had no anticoagulant. Of the 152 patients identified, 55 were not anti-coagulated after IVC filter placement. The incidence of death was 0.4 per 1000 filter days and 0.7 per 1000 filter days in the anti-coagulated and untreated groups respectively (p-value=0.06). After statistical correction for co-morbid conditions, the effect of anticoagulation was not significant (HR 0.82 CI 0.49-1.37, p-value 0.46). Age was a significant confounder that was associated with death. Increased BMI was protective. Indications for IVC filter placement were numerous, but similar between the two groups. Treatment with an approved anticoagulant is recommended after IVC filter placement for prevention of recurrent PE, however its effect may be attenuated by advanced age. In elderly patients that have undergone IVC filter placement for prevention of recurrent PE, survival may be more dependent on age and co-morbid conditions than exposure to anticoagulation. Copyright © 2017 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, H; Cormack, R; Bhagwat, M
Purpose: Gold nanoparticles (AuNP) are multifunctional platforms ideal for drug delivery, targeted imaging and radiosensitization. We have investigated quantitative imaging of AuNPs using on board imager (OBI) cone beam computed tomography (CBCT). To this end, we also present, for the first time, a novel method for k-edge imaging of AuNP by filter-based spectral shaping. Methods: We used a digital 25 cm diameter water phantom, embedded with 3 cm spheres filled with AuNPs of different concentrations (0 mg/ml – 16 mg/ml). A poly-energetic X-ray spectrum of 140 kVp from a conventional X-ray tube is shaped by balanced K-edge filters to createmore » an excess of photons right above the K-edge of gold at 80.7 keV. The filters consist of gold, tin, copper and aluminum foils. The phantom with appropriately assigned attenuation coefficients is forward projected onto a detector for each energy bin and then integrated. FKD reconstruction is performed on the integrated projections. Scatter, detector efficiency and noise are included. Results: We found that subtracting the results of two filter sets (Filter A:127 µm gold foil with 254 µm tin, 330 µm copper and 1 mm aluminum, and Filter B: 635 µm tin with 264 µm copper and 1 mm aluminum), provides substantial image contrast. The resulting filtered spectra match well below 80.7 keV, while maintaining sufficient X-ray quanta just above that. Voxel intensities of AuNP containing spheres increase linearly with AuNP concentration. K-edge imaging provides 18% more sensitivity than the tin filter alone, and 38% more sensitivity than the gold filter alone. Conclusion: We have shown that it is feasible to quantitatively detect AuNP distributions in a patient-sized phantom using clinical CBCT and K-edge spectral shaping.« less
Klandima, Somphan; Kruatrachue, Anchalee; Wongtapradit, Lawan; Nithipanya, Narong; Ratanaprakarn, Warangkana
2014-06-01
The problem of image quality in a large number of upper airway obstructed patients is the superimposition of the airway over the bone of the spine on the AP view. This problem was resolved by increasing KVp to high KVp technique and adding extra radiographic filters (copper filter) to reduce the sharpness of the bone and increase the clarity of the airway. However, this raises a concern that patients might be receiving an unnecessarily higher dose of radiation, as well as the effectiveness of the invented filter compared to the traditional filter. To evaluate the level of radiation dose that patients receive with the use of multi-layer filter compared to non-filter and to evaluate the image quality of the upper airways between using the radiographic filter (multi-layer filter) and the traditional filter (copperfilter). The attenuation curve of both filter materials was first identified. Then, both the filters were tested with Alderson Rando phantom to determine the appropriate exposure. Using the method described, a new type of filter called the multi-layer filter for imaging patients was developed. A randomized control trial was then performed to compare the effectiveness of the newly developed multi-layer filter to the copper filter. The research was conducted in patients with upper airway obstruction treated at Queen Sirikit National Institute of Child Health from October 2006 to September 2007. A total of 132 patients were divided into two groups. The experimental group used high kVp technique with multi-layer filter, while the control group used copper filter. A comparison of film interpretation between the multi-layer filter and the copper filter was made by a number of radiologists who were blinded to both to the technique and type of filter used. Patients had less radiation from undergoing the kVp technique with copper filter and multi-layer filter compared to the conventional technique, where no filter is used. Patients received approximately 65.5% less radiation dose using high kVp technique with multi-layer filter compared to the conventional technique, and 25.9% less than using the traditional copper filter 45% of the radiologists who participated in this study reported that the high kVp technique with multi-layer filter was better for diagnosing stenosis, or narrowing of the upper airways. 33% reported that, both techniques were equal, while 22% reported that the traditional copper filter allowed for better details of airway obstruction. These findings showed that the multi-layered filter was comparable to the copper filter in terms of film interpretation. Using the multi-layer filter resulted in patients receiving a lower dose of radiation, as well as similar film interpretation when compared to the traditional copper filter.
NASA Astrophysics Data System (ADS)
Nicolosi, E. M. G.; Quincey, P.; Font, A.; Fuller, G. W.
2018-02-01
The Attenuation Versus Evolved Carbon (AVEC) plot is a new way to represent thermal-optical organic carbon/elemental carbon (OC/EC) analysis data. The accumulated carbon concentration is plotted against the attenuation (ln (I0/I)). Unlike the thermogram, it provides information about the sample properties rather than the instantaneous instrument sensor status. The plot can be used to refine the determination of OC and EC split point, either from consideration of laser instability or transit time within the instrument; to investigate the optical properties of the particles; and to spot the early evolution of pyrolysed carbon (PC) and/or EC during the inert phase. 168 samples from three sites were studied. The gradient of the AVEC plot curve in the oxygenated phase provides information about the mass absorption cross section (σ) of the particles leaving the filter. The σ of the PC generated in the higher temperature Quartz protocol was greater than the PC generated in the lower temperature EUSAAR_2 protocol. Also, in both cases the PC evolved at a lower temperature in the oxygenated phase than the native EC. To minimise the shadowing effect, σ was also measured for the particles leaving the filter at the end of the analysis. These σ values, which are expected to be a combination of inherent σ together with fixed instrumental factors, were consistent between the different sites (45 ± 10 m2 g-1 in rural samples, 42 ± 8 m2 g-1 in urban samples and 35 ± 14 m2 g-1 in roadside samples). The AVEC plot can be generated from the data routinely produced by the analytical instrument using the R-code supplied in the supplementary material.
NASA Astrophysics Data System (ADS)
Hashemi, Sayed Masoud; Lee, Young; Eriksson, Markus; Nordström, Hâkan; Mainprize, James; Grouza, Vladimir; Huynh, Christopher; Sahgal, Arjun; Song, William Y.; Ruschin, Mark
2017-03-01
A Contrast and Attenuation-map (CT-number) Linearity Improvement (CALI) framework is proposed for cone-beam CT (CBCT) images used for brain stereotactic radiosurgery (SRS). The proposed framework is used together with our high spatial resolution iterative reconstruction algorithm and is tailored for the Leksell Gamma Knife ICON (Elekta, Stockholm, Sweden). The incorporated CBCT system in ICON facilitates frameless SRS planning and treatment delivery. The ICON employs a half-cone geometry to accommodate the existing treatment couch. This geometry increases the amount of artifacts and together with other physical imperfections causes image inhomogeneity and contrast reduction. Our proposed framework includes a preprocessing step, involving a shading and beam-hardening artifact correction, and a post-processing step to correct the dome/capping artifact caused by the spatial variations in x-ray energy generated by bowtie-filter. Our shading correction algorithm relies solely on the acquired projection images (i.e. no prior information required) and utilizes filtered-back-projection (FBP) reconstructed images to generate a segmented bone and soft-tissue map. Ideal projections are estimated from the segmented images and a smoothed version of the difference between the ideal and measured projections is used in correction. The proposed beam-hardening and dome artifact corrections are segmentation free. The CALI was tested on CatPhan, as well as patient images acquired on the ICON system. The resulting clinical brain images show substantial improvements in soft contrast visibility, revealing structures such as ventricles and lesions which were otherwise un-detectable in FBP-reconstructed images. The linearity of the reconstructed attenuation-map was also improved, resulting in more accurate CT#.
Methods to assess carbonaceous aerosol sampling artifacts for IMPROVE and other long-term networks.
Watson, John G; Chow, Judith C; Chen, L W Antony; Frank, Neil H
2009-08-01
Volatile organic compounds (VOCs) and semi-volatile organic compounds (SVOCs) adsorb to quartz fiber filters during fine and coarse particulate matter (PM2.5 and PM10, respectively) sampling for thermal/optical carbon analysis that measures organic carbon (OC) and elemental carbon (EC). Particulate SVOCs can evaporate after collection, with a small portion adsorbed within the filter. Adsorbed organic gases are measured as particulate OC, so passive field blanks, backup filters, prefilter organic denuders, and regression methods have been applied to compensate for positive OC artifacts in several long-term chemical speciation networks. Average backup filter OC levels from the Interagency Monitoring of Protected Visual Environments (IMPROVE) network were approximately 19% higher than field blank values. This difference is within the standard deviation of the average and likely results from low SVOC concentrations in the rural to remote environments of most IMPROVE sites. Backup filters from an urban (Fort Meade, MD) site showed twice the OC levels of field blanks. Sectioning backup filters from top to bottom showed nonuniform OC densities within the filter, contrary to the assumption that VOCs and SVOCs on a backup filter equal those on the front filter. This nonuniformity may be partially explained by evaporation and readsorption of vapors in different parts of the front and backup quartz fiber filter owing to temperature, relative humidity, and ambient concentration changes throughout a 24-hr sample duration. OC-PM2.5 regression analysis and organic denuder approaches demonstrate negative sampling artifact from both Teflon membrane and quartz fiber filters.
NASA Astrophysics Data System (ADS)
Diederich, M.; Ryzhkov, A.; Simmer, C.; Mühlbauer, K.
2011-12-01
The amplitude a of radar wave reflected by meteorological targets can be misjudged due to several factors. At X band wavelength, attenuation of the radar beam by hydro meteors reduces the signal strength enough to be a significant source of error for quantitative precipitation estimation. Depending on the surrounding orography, the radar beam may be partially blocked when scanning at low elevation angles, and the knowledge of the exact amount of signal loss through beam blockage becomes necessary. The phase shift between the radar signals at horizontal and vertical polarizations is affected by the hydrometeors that the beam travels through, but remains unaffected by variations in signal strength. This has allowed for several ways of compensating for the attenuation of the signal, and for consistency checks between these variables. In this study, we make use of several weather radars and gauge network measuring in the same area to examine the effectiveness of several methods of attenuation and beam blockage corrections. The methods include consistency checks of radar reflectivity and specific differential phase, calculation of beam blockage using a topography map, estimating attenuation using differential propagation phase, and the ZPHI method proposed by Testud et al. in 2000. Results show the high effectiveness of differential phase in estimating attenuation, and potential of the ZPHI method to compensate attenuation, beam blockage, and calibration errors.
NASA Astrophysics Data System (ADS)
Bellefleur, G.; Riedel, M.; Brent, T.
2007-05-01
Wave attenuation is an important physical property of hydrate-bearing sediments that is rarely taken into account in site characterization with seismic data. We present a field example showing improved images of hydrate- bearing sediments on seismic data after compensation of attenuation effects. Compressional quality factors (Q) are estimated from zero-offset Vertical Seismic Profiling data acquired at Mallik, Northwest Territories, Canada. During the last 10 years, two internationally-partnered research drilling programs have intersected three major intervals of sub-permafrost gas hydrates at Mallik, and have successfully extracted core samples containing significant amount of gas hydrates. Individual gas hydrate intervals are up to 40m in thickness and are characterized by high in situ gas hydrate saturation, sometimes exceeding 80% of pore volume of unconsolidated clastic sediments having average porosities ranging from 25% to 40%. The Q-factors obtained from the VSP data demonstrate significant wave attenuation for permafrost and hydrate- bearing sediments. These results are in agreement with previous attenuation estimates from sonic logs and crosshole data at different frequency intervals. The Q-factors obtained from VSP data were used to compensate attenuation effects on surface 3D seismic data acquired over the Mallik gas hydrate research wells. Intervals of gas hydrate on surface seismic data are characterized by strong reflectivity and effects from attenuation are not perceptible from a simple visual inspection of the data. However, the application of an inverse Q-filter increases the resolution of the data and improves correlation with log data, particularly for the shallowest gas hydrate interval. Compensation of the attenuation effects of the permafrost likely explains most of the improvements for the shallow gas hydrate zone. Our results show that characterization of the Mallik gas hydrates with seismic data not corrected for attenuation would tend to overestimate thicknesses and lateral extent of hydrate-bearing strata and hence, the volume of hydrates in place.
Convex blind image deconvolution with inverse filtering
NASA Astrophysics Data System (ADS)
Lv, Xiao-Guang; Li, Fang; Zeng, Tieyong
2018-03-01
Blind image deconvolution is the process of estimating both the original image and the blur kernel from the degraded image with only partial or no information about degradation and the imaging system. It is a bilinear ill-posed inverse problem corresponding to the direct problem of convolution. Regularization methods are used to handle the ill-posedness of blind deconvolution and get meaningful solutions. In this paper, we investigate a convex regularized inverse filtering method for blind deconvolution of images. We assume that the support region of the blur object is known, as has been done in a few existing works. By studying the inverse filters of signal and image restoration problems, we observe the oscillation structure of the inverse filters. Inspired by the oscillation structure of the inverse filters, we propose to use the star norm to regularize the inverse filter. Meanwhile, we use the total variation to regularize the resulting image obtained by convolving the inverse filter with the degraded image. The proposed minimization model is shown to be convex. We employ the first-order primal-dual method for the solution of the proposed minimization model. Numerical examples for blind image restoration are given to show that the proposed method outperforms some existing methods in terms of peak signal-to-noise ratio (PSNR), structural similarity (SSIM), visual quality and time consumption.
Seismic random noise removal by delay-compensation time-frequency peak filtering
NASA Astrophysics Data System (ADS)
Yu, Pengjun; Li, Yue; Lin, Hongbo; Wu, Ning
2017-06-01
Over the past decade, there has been an increasing awareness of time-frequency peak filtering (TFPF) due to its outstanding performance in suppressing non-stationary and strong seismic random noise. The traditional approach based on time-windowing achieves local linearity and meets the unbiased estimation. However, the traditional TFPF (including the improved algorithms with alterable window lengths) could hardly relieve the contradiction between removing noise and recovering the seismic signal, and this situation is more obvious in wave crests and troughs, even for alterable window lengths (WL). To improve the efficiency of the algorithm, the following TFPF in the time-space domain is applied, such as in the Radon domain and radial trace domain. The time-space transforms obtain a reduced-frequency input to reduce the TFPF error and stretch the desired signal along a certain direction, therefore the time-space development brings an improvement by both enhancing reflection events and attenuating noise. It still proves limited in application because the direction should be matched as a straight line or quadratic curve. As a result, waveform distortion and false seismic events may appear when processing the complex stratum record. The main emphasis in this article is placed on the time-space TFPF applicable expansion. The reconstructed signal in delay-compensation TFPF, which is generated according to the similarity among the reflection events, overcomes the limitation of the direction curve fitting. Moreover, the reconstructed signal just meets the TFPF linearity unbiased estimation and integrates signal reservation with noise attenuation. Experiments on both the synthetic model and field data indicate that delay-compensation TFPF has a better performance over the conventional filtering algorithms.
Pangnakorn, P; Nonthabenjawan, R; Ekgasit, S; Thammacharoen, C; Pattanaargson Wanichwecharungruang, S
2007-02-01
Photoisomerization and photodimerization of a widely used UVB filter, 2-ethylhexy-4-methoxycinnamate (EHMC) on a ZnSe surface and baby mouse (Mus musculus Linn.) skin were monitored using attenuated total reflection Fourier transform infrared spectroscopy (ATR-FT-IR). Differentiation between the E- and the Z-EHMC could be achieved by examining the infrared (IR) peak at 981 cm(-1) (b peak), which corresponds to the CH rocking deformation vibration of Ph-CH=CH- detected only in the E configuration. By plotting the ratios of the peak area of the b peak and an internal standard peak (1060-998 cm(-1)) against mole percentage of Z-isomer in the E-Z mixtures, a linear calibration plot was obtained. Thus, a simple estimation of the mole percentage of each configuration in a sample was obtained. At the same UVB exposure, photostationary equilibrium of the E/Z isomerization on the surface varied with the applied amounts of EHMC. Photoisomerizations on ZnSe and on baby mouse skin were comparable. Less than 10% of E-EHMC changed configuration when the mouse skins applied with 1.0-4.0 mg/cm(2) E-EHMC were exposed to sunlight for 60 min (UVB radiant exposure of approximately 0.30 J/cm(2)). This corresponded to less than 5% loss in UV filtering efficiency. However, at a typical EHMC skin coverage ( approximately 0.2 mg/cm(2)), 0.30 J/cm(2) UVB exposure induced approximately 50% photoisomerization resulting in 25% loss of UV filtering efficiency. No photodimerization was detected even at the extreme EHMC coverage of 4.0 mg/cm(2) after a UVB exposure of 0.90 J/cm(2).
Optimization of the reconstruction parameters in [123I]FP-CIT SPECT
NASA Astrophysics Data System (ADS)
Niñerola-Baizán, Aida; Gallego, Judith; Cot, Albert; Aguiar, Pablo; Lomeña, Francisco; Pavía, Javier; Ros, Domènec
2018-04-01
The aim of this work was to obtain a set of parameters to be applied in [123I]FP-CIT SPECT reconstruction in order to minimize the error between standardized and true values of the specific uptake ratio (SUR) in dopaminergic neurotransmission SPECT studies. To this end, Monte Carlo simulation was used to generate a database of 1380 projection data-sets from 23 subjects, including normal cases and a variety of pathologies. Studies were reconstructed using filtered back projection (FBP) with attenuation correction and ordered subset expectation maximization (OSEM) with correction for different degradations (attenuation, scatter and PSF). Reconstruction parameters to be optimized were the cut-off frequency of a 2D Butterworth pre-filter in FBP, and the number of iterations and the full width at Half maximum of a 3D Gaussian post-filter in OSEM. Reconstructed images were quantified using regions of interest (ROIs) derived from Magnetic Resonance scans and from the Automated Anatomical Labeling map. Results were standardized by applying a simple linear regression line obtained from the entire patient dataset. Our findings show that we can obtain a set of optimal parameters for each reconstruction strategy. The accuracy of the standardized SUR increases when the reconstruction method includes more corrections. The use of generic ROIs instead of subject-specific ROIs adds significant inaccuracies. Thus, after reconstruction with OSEM and correction for all degradations, subject-specific ROIs led to errors between standardized and true SUR values in the range [‑0.5, +0.5] in 87% and 92% of the cases for caudate and putamen, respectively. These percentages dropped to 75% and 88% when the generic ROIs were used.
Two-dimensional grating guided-mode resonance tunable filter.
Kuo, Wen-Kai; Hsu, Che-Jung
2017-11-27
A two-dimensional (2D) grating guided-mode resonance (GMR) tunable filter is experimentally demonstrated using a low-cost two-step nanoimprinting technology with a one-dimensional (1D) grating polydimethylsiloxane mold. For the first nanoimprinting, we precisely control the UV LED irradiation dosage and demold the device when the UV glue is partially cured and the 1D grating mold is then rotated by three different angles, 30°, 60°, and 90°, for the second nanoimprinting to obtain 2D grating structures with different crossing angles. A high-refractive-index film ZnO is then coated on the surface of the grating structure to form the GMR filter devices. The simulation and experimental results demonstrate that the passband central wavelength of the filter can be tuned by rotating the device to change azimuth angle of the incident light. We compare these three 2D GMR filters with differential crossing angles and find that the filter device with a crossing angle of 60° exhibits the best performance. The tunable range of its central wavelength is 668-742 nm when the azimuth angle varies from 30° to 90°.
Determining attenuation properties of interfering fast and slow ultrasonic waves in cancellous bone.
Nelson, Amber M; Hoffman, Joseph J; Anderson, Christian C; Holland, Mark R; Nagatani, Yoshiki; Mizuno, Katsunori; Matsukawa, Mami; Miller, James G
2011-10-01
Previous studies have shown that interference between fast waves and slow waves can lead to observed negative dispersion in cancellous bone. In this study, the effects of overlapping fast and slow waves on measurements of the apparent attenuation as a function of propagation distance are investigated along with methods of analysis used to determine the attenuation properties. Two methods are applied to simulated data that were generated based on experimentally acquired signals taken from a bovine specimen. The first method uses a time-domain approach that was dictated by constraints imposed by the partial overlap of fast and slow waves. The second method uses a frequency-domain log-spectral subtraction technique on the separated fast and slow waves. Applying the time-domain analysis to the broadband data yields apparent attenuation behavior that is larger in the early stages of propagation and decreases as the wave travels deeper. In contrast, performing frequency-domain analysis on the separated fast waves and slow waves results in attenuation coefficients that are independent of propagation distance. Results suggest that features arising from the analysis of overlapping two-mode data may represent an alternate explanation for the previously reported apparent dependence on propagation distance of the attenuation coefficient of cancellous bone. © 2011 Acoustical Society of America
Determining attenuation properties of interfering fast and slow ultrasonic waves in cancellous bone
Nelson, Amber M.; Hoffman, Joseph J.; Anderson, Christian C.; Holland, Mark R.; Nagatani, Yoshiki; Mizuno, Katsunori; Matsukawa, Mami; Miller, James G.
2011-01-01
Previous studies have shown that interference between fast waves and slow waves can lead to observed negative dispersion in cancellous bone. In this study, the effects of overlapping fast and slow waves on measurements of the apparent attenuation as a function of propagation distance are investigated along with methods of analysis used to determine the attenuation properties. Two methods are applied to simulated data that were generated based on experimentally acquired signals taken from a bovine specimen. The first method uses a time-domain approach that was dictated by constraints imposed by the partial overlap of fast and slow waves. The second method uses a frequency-domain log-spectral subtraction technique on the separated fast and slow waves. Applying the time-domain analysis to the broadband data yields apparent attenuation behavior that is larger in the early stages of propagation and decreases as the wave travels deeper. In contrast, performing frequency-domain analysis on the separated fast waves and slow waves results in attenuation coefficients that are independent of propagation distance. Results suggest that features arising from the analysis of overlapping two-mode data may represent an alternate explanation for the previously reported apparent dependence on propagation distance of the attenuation coefficient of cancellous bone. PMID:21973378
NASA Technical Reports Server (NTRS)
Tian, Lin; Heymsfield, G. M.; Srivastava, R. C.; Starr, D. OC. (Technical Monitor)
2001-01-01
Observations by the airborne X-band Doppler radar (EDOP) and the NCAR S-band polarimetric (S-POL) radar from two field experiments are used to evaluate the Surface ref'ercnce technique (SRT) for measuring the path integrated attenuation (PIA) and to study attenuation in deep convective storms. The EDOP, flying at an altitude of 20 km, uses a nadir beam and a forward pointing beam. It is found that over land, the surface scattering cross-section is highly variable at nadir incidence but relatively stable at forward incidence. It is concluded that measurement by the forward beam provides a viable technique for measuring PIA using the SRT. Vertical profiles of peak attenuation coefficient are derived in vxo deep convective storms by the dual-wavelength method. Using the measured Doppler velocity, the reflectivities at. the two wavelengths, the differential reflectivity and the estimated attenuation coefficients, it is shown that: supercooled drops and dry ice particles probably co-existed above the melting level in regions of updraft, that water-coated partially melted ice particles probably contributed to high attenuation below the melting level, and that the data are not readil explained in terms of a gamma function raindrop size distribution.
Hybrid modelling of a high-power X-ray attenuator plasma.
Martín Ortega, Álvaro; Lacoste, Ana; Minea, Tiberiu
2018-05-01
X-ray gas attenuators act as stress-free high-pass filters for synchrotron and free-electron laser beamlines to reduce the heat load in downstream optical elements without affecting other properties of the X-ray beam. The absorption of the X-ray beam triggers a cascade of processes that ionize and heat up the gas locally, changing its density and therefore the X-ray absorption. Aiming to understand and predict the behaviour of the gas attenuator in terms of efficiency versus gas pressure, a hybrid model has been developed, combining three approaches: an analytical description of the X-ray absorption; Monte Carlo for the electron thermalization; and a fluid treatment for the electron diffusion, recombination and excited-states relaxation. The model was applied to an argon-filled attenuator prototype built and tested at the European Synchrotron Radiation Facility, at a pressure of 200 mbar and assuming stationary conditions. The results of the model showed that the electron population thermalizes within a few nanoseconds after the X-ray pulse arrival and it occurs just around the X-ray beam path, recombining in the bulk of the gas rather than diffusing to the attenuator walls. The gas temperature along the beam path reached 850 K for 770 W of incident power and 182 W m -1 of absorbed power. Around 70% of the absorbed power is released as visible and UV radiation rather than as heat to the gas. Comparison of the power absorption with the experiment showed an overall agreement both with the plasma radial profile and power absorption trend, the latter within an error smaller than 20%. This model can be used for the design and operation of synchrotron gas attenuators and as a base for a time-dependent model for free-electron laser attenuators.
A mean-based filter to remove power line harmonic noise from seismic reflection data
NASA Astrophysics Data System (ADS)
Karslı, Hakan; Dondurur, Derman
2018-06-01
Power line harmonic noise generated by power lines during the seismic data acquisition in land and marine seismic surveys generally appears as a single frequency with 50/60 Hz (or multiples of these frequencies) and contaminates seismic data leading to complicate the identification of fine details in the data. Commonly applied method during seismic data processing to remove the harmonic noise is classical notch filter (or very narrow band-stop filter), however, it also attenuates all recorded data around the notch frequencies and results in a complete loss of available information which corresponds to fine details in the seismic data. In this study, we introduce an application of the algorithm of iterative trimmed and truncated mean filter method (ITTM) to remove the harmonic noise from seismic data, and here, we name the method as local ITTM (LITTM) since we applied it to the seismic data locally in spectral domain. In this method, an optimal value is iteratively searched depending on a threshold value by trimming and truncating process for the spectral amplitude samples within the specified spectral window. Therefore, the LITTM filter converges to the median, but, there is no need to sort the data as in the case of conventional median filters. On the other hand, the LITTM filtering process doesn't require any reference signal or a precise estimate of the fundamental frequency of the harmonic noise, and only approximate frequency band of the noise within the amplitude spectra is considered. The only required parameter of the method is the width of this frequency band in the spectral domain. The LITTM filter is first applied to synthetic data and then we analyze a real marine dataset to compare the quality of the output after removing the power line noise by classical notch, median and proposed LITTM filters. We observe that the power line harmonic noise is completely filtered out by LITTM filter, and unlike the conventional notch filter, without any damage on the available frequencies around the notch frequency band. It also provides a more balanced amplitude spectrum since it does not produce amplitude notches in the spectrum.
Filtering observations without the initial guess
NASA Astrophysics Data System (ADS)
Chin, T. M.; Abbondanza, C.; Gross, R. S.; Heflin, M. B.; Parker, J. W.; Soja, B.; Wu, X.
2017-12-01
Noisy geophysical observations sampled irregularly over space and time are often numerically "analyzed" or "filtered" before scientific usage. The standard analysis and filtering techniques based on the Bayesian principle requires "a priori" joint distribution of all the geophysical parameters of interest. However, such prior distributions are seldom known fully in practice, and best-guess mean values (e.g., "climatology" or "background" data if available) accompanied by some arbitrarily set covariance values are often used in lieu. It is therefore desirable to be able to exploit efficient (time sequential) Bayesian algorithms like the Kalman filter while not forced to provide a prior distribution (i.e., initial mean and covariance). An example of this is the estimation of the terrestrial reference frame (TRF) where requirement for numerical precision is such that any use of a priori constraints on the observation data needs to be minimized. We will present the Information Filter algorithm, a variant of the Kalman filter that does not require an initial distribution, and apply the algorithm (and an accompanying smoothing algorithm) to the TRF estimation problem. We show that the information filter allows temporal propagation of partial information on the distribution (marginal distribution of a transformed version of the state vector), instead of the full distribution (mean and covariance) required by the standard Kalman filter. The information filter appears to be a natural choice for the task of filtering observational data in general cases where prior assumption on the initial estimate is not available and/or desirable. For application to data assimilation problems, reduced-order approximations of both the information filter and square-root information filter (SRIF) have been published, and the former has previously been applied to a regional configuration of the HYCOM ocean general circulation model. Such approximation approaches are also briefed in the presentation.
Design of a broadband active silencer using μ-synthesis
NASA Astrophysics Data System (ADS)
Bai, Mingsian R.; Zeung, Pingshun
2004-01-01
A robust spatially feedforward controller is developed for broadband attenuation of noise in ducts. To meet the requirements of robust performance and robust stability in the presence of plant uncertainties, a μ-synthesis procedure via D- K iteration is exploited to obtain the optimal controller. This approach considers uncertainties as modelling errors of the nominal plant in high frequency and is implemented using a floating point digital signal processor (DSP). Experimental investigation was undertaken on a finite-length duct to justify the proposed controller. The μ- controller is compared to other control algorithms such as the H2 method, the H∞ method and the filtered-U least mean square (FULMS) algorithm. Experimental results indicate that the proposed system has attained 25.8 dB maximal attenuation in the band 250-650 Hz.
Hunter, Chad R R N; Klein, Ran; Beanlands, Rob S; deKemp, Robert A
2016-04-01
Patient motion is a common problem during dynamic positron emission tomography (PET) scans for quantification of myocardial blood flow (MBF). The purpose of this study was to quantify the prevalence of body motion in a clinical setting and evaluate with realistic phantoms the effects of motion on blood flow quantification, including CT attenuation correction (CTAC) artifacts that result from PET-CT misalignment. A cohort of 236 sequential patients was analyzed for patient motion under resting and peak stress conditions by two independent observers. The presence of motion, affected time-frames, and direction of motion was recorded; discrepancy between observers was resolved by consensus review. Based on these results, patient body motion effects on MBF quantification were characterized using the digital NURBS-based cardiac-torso phantom, with characteristic time activity curves (TACs) assigned to the heart wall (myocardium) and blood regions. Simulated projection data were corrected for attenuation and reconstructed using filtered back-projection. All simulations were performed without noise added, and a single CT image was used for attenuation correction and aligned to the early- or late-frame PET images. In the patient cohort, mild motion of 0.5 ± 0.1 cm occurred in 24% and moderate motion of 1.0 ± 0.3 cm occurred in 38% of patients. Motion in the superior/inferior direction accounted for 45% of all detected motion, with 30% in the superior direction. Anterior/posterior motion was predominant (29%) in the posterior direction. Left/right motion occurred in 24% of cases, with similar proportions in the left and right directions. Computer simulation studies indicated that errors in MBF can approach 500% for scans with severe patient motion (up to 2 cm). The largest errors occurred when the heart wall was shifted left toward the adjacent lung region, resulting in a severe undercorrection for attenuation of the heart wall. Simulations also indicated that the magnitude of MBF errors resulting from motion in the superior/inferior and anterior/posterior directions was similar (up to 250%). Body motion effects were more detrimental for higher resolution PET imaging (2 vs 10 mm full-width at half-maximum), and for motion occurring during the mid-to-late time-frames. Motion correction of the reconstructed dynamic image series resulted in significant reduction in MBF errors, but did not account for the residual PET-CTAC misalignment artifacts. MBF bias was reduced further using global partial-volume correction, and using dynamic alignment of the PET projection data to the CT scan for accurate attenuation correction during image reconstruction. Patient body motion can produce MBF estimation errors up to 500%. To reduce these errors, new motion correction algorithms must be effective in identifying motion in the left/right direction, and in the mid-to-late time-frames, since these conditions produce the largest errors in MBF, particularly for high resolution PET imaging. Ideally, motion correction should be done before or during image reconstruction to eliminate PET-CTAC misalignment artifacts.
Polarization-Insensitive Tunable Optical Filters based on Liquid Crystal Polarization Gratings
NASA Astrophysics Data System (ADS)
Nicolescu, Elena
Tunable optical filters are widely used for a variety of applications including spectroscopy, optical communication networks, remote sensing, and biomedical imaging and diagnostics. All of these application areas can greatly benefit from improvements in the key characteristics of the tunable optical filters embedded in them. Some of these key parameters include peak transmittance, bandwidth, tuning range, and transition width. In recent years research efforts have also focused on miniaturizing tunable optical filters into physically small packages for compact portable spectroscopy and hyperspectral imaging applications such as real-time medical diagnostics and defense applications. However, it is important that miniaturization not have a detrimental effect on filter performance. The overarching theme of this dissertation is to explore novel configurations of Polarization Gratings (PGs) as simple, low-cost, polarization-insensitive alternatives to conventional optical filtering technologies for applications including hyperspectral imaging and telecommunications. We approach this goal from several directions with a combination of theory and experimental demonstration leading to, in our opinion, a significant contribution to the field. We present three classes of tunable optical filters, the first of which is an angle-filtering scheme where the stop-band wavelengths are redirected off axis and the passband is transmitted on-axis. This is achieved using a stacked configuration of polarization gratings of various thicknesses. To improve this class of filter, we also introduce a novel optical element, the Bilayer Polarization Grating, exhibiting unique optical properties and demonstrating complex anchoring conditions with high quality. The second class of optical filter is analogous to a Lyot filter, utilizing stacks of static or tunable waveplates sandwiched with polarizing elements. However, we introduce a new configuration using PGs and static waveplates to replace the polarizers in the system, thereby greatly increasing the filter throughput. We then turn our attention to a Fourier filtering technique. This is a fundamentally different filtering approach involving a single PG where the filtering functionality involves selecting a spectral band with a movable aperture or slit and a diffractive element (PG in our case). Finally, we study the integration of a PG in a multi-channel wavelength blocker system focusing on the practical and fundamental limitations of using a PG as a variable optical attenuator/wavelength blocker in a commercial optical telecommunications network.
NASA Astrophysics Data System (ADS)
Xu, Wenjun; Tang, Chen; Zheng, Tingyue; Qiu, Yue
2018-07-01
Oriented partial differential equations (OPDEs) have been demonstrated to be a powerful tool for preserving the integrity of fringes while filtering electronic speckle pattern interferometry (ESPI) fringe patterns. However, the main drawback of OPDEs-based methods is that many iterations are often needed, which causes the change in the shape of fringes. Change in the shape of fringes will affect the accuracy of subsequent fringe analysis. In this paper, we focus on preserving the shape of fringes while filtering, suggested here for the first time. We propose a shape-preserving OPDE for ESPI fringe patterns denoising by introducing a new fidelity term to the previous second-order single oriented PDE (SOOPDE). In our proposed fidelity term, the evolution image is subtracted from the shrinkage result of original noisy image by shearlet transform. Our proposed shape-preserving OPDE is capable of eliminating noise effectively, keeping the integrity of fringes, and more importantly, preserving the shape of fringes. We test the proposed shape-preserving OPDE on three computer-simulated and three experimentally obtained ESPI fringe patterns with poor quality. Furthermore, we compare our model with three representative filtering methods, including the widely used SOOPDE, shearlet transform and coherence-enhancing diffusion (CED). We also compare our proposed fidelity term with the traditional fidelity term. Experimental results show that the proposed shape-preserving OPDE not only yields filtered images with visual quality on par with those by CED which is the state-of-the-art method for ESPI fringe patterns denoising, but also keeps the shape of ESPI fringe patterns.
Single photon laser altimeter data processing, analysis and experimental validation
NASA Astrophysics Data System (ADS)
Vacek, Michael; Peca, Marek; Michalek, Vojtech; Prochazka, Ivan
2015-10-01
Spaceborne laser altimeters are common instruments on-board the rendezvous spacecraft. This manuscript deals with the altimeters using a single photon approach, which belongs to the family of time-of-flight range measurements. Moreover, the single photon receiver part of the altimeter may be utilized as an Earth-to-spacecraft link enabling one-way ranging, time transfer and data transfer. The single photon altimeters evaluate actual altitude through the repetitive detections of single photons of the reflected laser pulses. We propose the single photon altimeter signal processing and data mining algorithm based on the Poisson statistic filter (histogram method) and the modified Kalman filter, providing all common altimetry products (altitude, slope, background photon flux and albedo). The Kalman filter is extended for the background noise filtering, the varying slope adaptation and the non-causal extension for an abrupt slope change. Moreover, the algorithm partially removes the major drawback of a single photon altitude reading, namely that the photon detection measurement statistics must be gathered. The developed algorithm deduces the actual altitude on the basis of a single photon detection; thus, being optimal in the sense that each detected signal photon carrying altitude information is tracked and no altitude information is lost. The algorithm was tested on the simulated datasets and partially cross-probed with the experimental data collected using the developed single photon altimeter breadboard based on the microchip laser with the pulse energy on the order of microjoule and the repetition rate of several kilohertz. We demonstrated that such an altimeter configuration may be utilized for landing or hovering a small body (asteroid, comet).
Cebeci Maltaş, Derya; Kwok, Kaho; Wang, Ping; Taylor, Lynne S; Ben-Amotz, Dor
2013-06-01
Identifying pharmaceutical ingredients is a routine procedure required during industrial manufacturing. Here we show that a recently developed Raman compressive detection strategy can be employed to classify various widely used pharmaceutical materials using a hybrid supervised/unsupervised strategy in which only two ingredients are used for training and yet six other ingredients can also be distinguished. More specifically, our liquid crystal spatial light modulator (LC-SLM) based compressive detection instrument is trained using only the active ingredient, tadalafil, and the excipient, lactose, but is tested using these and various other excipients; microcrystalline cellulose, magnesium stearate, titanium (IV) oxide, talc, sodium lauryl sulfate and hydroxypropyl cellulose. Partial least squares discriminant analysis (PLS-DA) is used to generate the compressive detection filters necessary for fast chemical classification. Although the filters used in this study are trained on only lactose and tadalafil, we show that all the pharmaceutical ingredients mentioned above can be differentiated and classified using PLS-DA compressive detection filters with an accumulation time of 10ms per filter. Copyright © 2013 Elsevier B.V. All rights reserved.
Essentially nonoscillatory postprocessing filtering methods
NASA Technical Reports Server (NTRS)
Lafon, F.; Osher, S.
1992-01-01
High order accurate centered flux approximations used in the computation of numerical solutions to nonlinear partial differential equations produce large oscillations in regions of sharp transitions. Here, we present a new class of filtering methods denoted by Essentially Nonoscillatory Least Squares (ENOLS), which constructs an upgraded filtered solution that is close to the physically correct weak solution of the original evolution equation. Our method relies on the evaluation of a least squares polynomial approximation to oscillatory data using a set of points which is determined via the ENO network. Numerical results are given in one and two space dimensions for both scalar and systems of hyperbolic conservation laws. Computational running time, efficiency, and robustness of method are illustrated in various examples such as Riemann initial data for both Burgers' and Euler's equations of gas dynamics. In all standard cases, the filtered solution appears to converge numerically to the correct solution of the original problem. Some interesting results based on nonstandard central difference schemes, which exactly preserve entropy, and have been recently shown generally not to be weakly convergent to a solution of the conservation law, are also obtained using our filters.
Three-dimensional seismic depth migration
NASA Astrophysics Data System (ADS)
Zhou, Hongbo
1998-12-01
One-pass 3-D modeling and migration for poststack seismic data may be implemented by replacing the traditional 45sp° one-way wave equation (a third-order partial differential equation) with a pair of second and first order partial differential equations. Except for an extra correction term, the resulting second order equation has a form similar to Claerbout's 15sp° one-way wave equation, which is known to have a nearly circular horizontal impulse response. In this approach, there is no need to compensate for splitting errors. Numerical tests on synthetic data show that this algorithm has the desirable attributes of being second-order in accuracy and economical to solve. A modification of the Crank-Nicholson implementation maintains stability. Absorbing boundary conditions play an important role in one-way wave extrapolations by reducing reflections at grid edges. Clayton and Engquist's 2-D absorbing boundary conditions for one-way wave extrapolation by depth-stepping in the frequency domain are extended to 3-D using paraxial approximations of the scalar wave equation. Internal consistency is retained by incorporating the interior extrapolation equation with the absorbing boundary conditions. Numerical schemes are designed to make the proposed absorbing boundary conditions both mathematically correct and efficient with negligible extra cost. Synthetic examples illustrate the effectiveness of the algorithm for extrapolation with the 3-D 45sp° one-way wave equation. Frequency-space domain Butterworth and Chebyshev dip filters are implemented. By regrouping the product terms in the filter transfer function into summations, a cascaded (serial) Butterworth dip filter can be made parallel. A parallel Chebyshev dip filter can be similarly obtained, and has the same form as the Butterworth filter; but has different coeffcients. One of the advantages of the Chebyshev filter is that it has a sharper transition zone than that of Butterworth filter of the same order. Both filters are incorporated into 3-D one-way frequency-space depth migration for evanescent energy removal and for phase compensation of splitting errors; a single filter achieves both goals. Synthetic examples illustrate the behavior of the parallel filters. For a given order of filter, the cost of the Butterworth and Chebyshev filters is the same. A Chebyshev filter is more effective for phase compensation than the Butterworth filter of the same order, at the expense of some wavenumber-dependent amplitude ripples. An analytical formula for geometrical spreading is derived for a horizontally layered transversely isotropic medium with a vertical symmetry axis. Under this expression, geometrical spreading can be determined only by the anisotropic parameters in the first layer, the traveltime derivatives, and source-receiver offset. An explicit, numerically feasible expression for geometrical spreading can be further obtained by considering some of the special cases of transverse isotropy, such as weak anisotropy or elliptic anisotropy. Therefore, with the techniques of non-hyerbolic moveout for transverse isotropic media, geometrical spreading can be calculated by using picked traveltimes of primary P-wave reflections without having to know the actual parameters in the deeper subsurface; no ray tracing is needed. Synthetic examples verify the algorithm and show that it is numerically feasible for calculation of geometrical spreading.
Thomas, Christoph; Krauss, Bernhard; Ketelsen, Dominik; Tsiflikas, Ilias; Reimann, Anja; Werner, Matthias; Schilling, David; Hennenlotter, Jörg; Claussen, Claus D; Schlemmer, Heinz-Peter; Heuschmid, Martin
2010-07-01
In dual energy (DE) computed tomography (CT), spectral shaping by additional filtration of the high energy spectrum can theoretically improve dual energy contrast. The aim of this in vitro study was to examine the influence of an additional tin filter for the differentiation of human urinary calculi by dual energy CT. A total of 36 pure human urinary calculi (uric acid, cystine, calciumoxalate monohydrate, calciumoxalate dihydrate, carbonatapatite, brushite, average diameter 10.5 mm) were placed in a phantom and imaged with 2 dual source CT scanners. One scanner was equipped with an additional tin (Sn) filter. Different combinations of tube voltages (140/80 kV, 140/100 kV, Sn140/100 kV, Sn140/80 kV, with Sn140 referring to 140 kV with the tin filter) were applied. Tube currents were adapted to yield comparable dose indices. Low- and high energy images were reconstructed. The calculi were segmented semiautomatically in the datasets and DE ratios (attenuation@low_kV/attenuation@high_kV) and were calculated for each calculus. DE contrasts (DE-ratio_material1/DE-ratio_material2) were computed for uric acid, cystine and calcified calculi and compared between the combinations of tube voltages. Using exclusively DE ratios, all uric acid, cystine and calcified calculi (as a group) could be differentiated in all protocols; the calcified calculi could not be differentiated among each other in any examination protocol. The highest DE ratios and DE contrasts were measured for the Sn140/80 protocol (53%-62% higher DE contrast than in the 140/80 kV protocol without additional filtration). The DE ratios and DE contrasts of the 80/140 kV and 100/Sn140 kV protocols were comparable. Uric acid, cystine and calcified calculi could be reliably differentiated by any of the protocols. A dose-neutral gain of DE contrast was found in the Sn-filter protocols, which might improve the differentiation of smaller calculi (Sn140/80 kV) and improve image quality and calculi differentiation in larger patients (Sn140/100 kV). However, even with the improved spectral separation of the Sn-filter protocols, the DE ratios of calcified calculi are not sufficiently distinct to allow a differentiation within this group.
ERIC Educational Resources Information Center
Liddle, Elizabeth B.; Hollis, Chris; Batty, Martin J.; Groom, Madeleine J.; Totman, John J.; Liotti, Mario; Scerif, Gaia; Liddle, Peter F.
2011-01-01
Background: Deficits characteristic of attention deficit/hyperactivity disorder (ADHD), including poor attention and inhibitory control, are at least partially alleviated by factors that increase engagement of attention, suggesting a hypodopaminergic reward deficit. Lapses of attention are associated with attenuated deactivation of the default…
Neurotrophins, including nerve growth factor (NGF) partially mediate many features of allergic airways disease including airway resistance. Exposure to diesel exhaust particles (DEP) associated with the combustion of diesel fuel exacerbates allergic airways responses. We tested t...
Partial attenuation of Marek's disease virus by manipulation of Di-codon bias
USDA-ARS?s Scientific Manuscript database
All species studied to date demonstrate a preference for certain codons over other synonymous codons (codon bias), a preference which is also observed for pairs of codons (di-codon bias). Previous studies using poliovirus and influenza virus as models have demonstrated the ability to cause attenuat...
Beam energy tracking system on Optima XEx high energy ion implanter
DOE Office of Scientific and Technical Information (OSTI.GOV)
David, Jonathan; Satoh, Shu; Wu Xiangyang
2012-11-06
The Axcelis Optima XEx high energy implanter is an RF linac-based implanter with 12 RF resonators for beam acceleration. Even though each acceleration field is an alternating, sinusoidal RF field, the well known phase-focusing principle produces a beam with a sharp quasi-monoenergetic energy spectrum. A magnetic energy filter after the linac further attenuates the low energy continuum in the energy spectrum often associated with RF acceleration. The final beam energy is a function of the phase and amplitude of the 12 resonators in the linac. When tuning a beam, the magnetic energy filter is set to the desired energy, andmore » each linac parameter is tuned to maximize the transmission through the filter. Once a beam is set up, all the parameters are stored in a recipe, which can be easily tuned and has proven to be quite repeatable. The magnetic field setting of the energy filter selects the beam energy from the RF Linac accelerator, and in-situ verification of beam energy in addition to the magnetic energy filter setting has long been desired. An independent energy tracking system was developed for this purpose, using the existing electrostatic beam scanner as a deflector to construct an in-situ electrostatic energy analyzer. This paper will describe the system and performance of the beam energy tracking system.« less
Jian, Wenjuan; Chen, Minyou; McFarland, Dennis J
2017-04-01
Phase-locking value (PLV) is a well-known feature in sensorimotor rhythm (SMR) based BCI. Zero-phase PLV has not been explored because it is generally regarded as the result of volume conduction. Because spatial filters are often used to enhance the amplitude (square root of band power (BP)) feature and attenuate volume conduction, they are frequently applied as pre-processing methods when computing PLV. However, the effects of spatial filtering on PLV are ambiguous. Therefore, this article aims to explore whether zero-phase PLV is meaningful and how this is influenced by spatial filtering. Based on archival EEG data of left and right hand movement tasks for 32 subjects, we compared BP and PLV feature using data with and without pre-processing by a large Laplacian. Results showed that using ear-referenced data, zero-phase PLV provided unique information independent of BP for task prediction which was not explained by volume conduction and was significantly decreased when a large Laplacian was applied. In other words, the large Laplacian eliminated the useful information in zero-phase PLV for task prediction suggesting that it contains effects of both amplitude and phase. Therefore, zero-phase PLV may have functional significance beyond volume conduction. The interpretation of spatial filtering may be complicated by effects of phase. Copyright © 2017 Elsevier Inc. All rights reserved.
Piccirilli, Gisela N; Escandar, Graciela M
2006-09-01
This paper demonstrates for the first time the power of a chemometric second-order algorithm for predicting, in a simple way and using spectrofluorimetric data, the concentration of analytes in the presence of both the inner-filter effect and unsuspected species. The simultaneous determination of the systemic fungicides carbendazim and thiabendazole was achieved and employed for the discussion of the scopes of the applied second-order chemometric tools: parallel factor analysis (PARAFAC) and partial least-squares with residual bilinearization (PLS/RBL). The chemometric study was performed using fluorescence excitation-emission matrices obtained after the extraction of the analytes over a C18-membrane surface. The ability of PLS/RBL to recognize and overcome the significant changes produced by thiabendazole in both the excitation and emission spectra of carbendazim is demonstrated. The high performance of the selected PLS/RBL method was established with the determination of both pesticides in artificial and real samples.
Thorman, A; Michael, C; De Bock, M; Howard, J
2016-07-01
A motional Stark effect polarimeter insensitive to polarized broadband light is proposed. Partially polarized background light is anticipated to be a significant source of systematic error for the ITER polarimeter. The proposed polarimeter is based on the standard dual photoelastic modulator approach, but with the introduction of a birefringent delay plate, it generates a sinusoidal spectral filter instead of the usual narrowband filter. The period of the filter is chosen to match the spacing of the orthogonally polarized Stark effect components, thereby increasing the effective signal level, but resulting in the destructive interference of the broadband polarized light. The theoretical response of the system to an ITER like spectrum is calculated and the broadband polarization tolerance is verified experimentally.
Li, Yan; Rashid, Azhar; Wang, Hongjie; Hu, Anyi; Lin, Lifeng; Yu, Chang-Ping; Chen, Meng; Sun, Qian
2018-08-15
Sulfamethoxazole (SMX) is a sulfonamide antibiotic, widely used as curative and preventive drug for human, animal, and aquaculture bacterial infections. Its residues have been ubiquitously detected in the surface waters and sediments. In the present study, SMX dissipation and kinetics was studied in the natural water samples from Jiulong River under simulated complex natural conditions as well as conditions to mimic various biotic and abiotic environmental conditions in isolation. Structural equation modeling (SEM) by employing partial least square technique in path coefficient analysis was used to investigate the direct and indirect contributions of different environmental factors in the natural attenuation of SMX. The model explained 81% of the variability in natural attenuation as a dependent variable under the influence of sole effects of direct photo-degradation, indirect photo-degradation, hydrolysis, microbial degradation and bacterial degradation. The results of SEM suggested that the direct and indirect photo-degradation were the major pathways in the SMX natural attenuation. However, other biotic and abiotic factors also play a mediatory role during the natural attenuation and other processes. Furthermore, the potential transformation products of SMX were identified and their toxicity was evaluated. Copyright © 2018 Elsevier B.V. All rights reserved.
Forward-masking based gain control in odontocete biosonar: an evoked-potential study.
Supin, Alexander Ya; Nachtigall, Paul E; Breese, Marlee
2009-04-01
Auditory evoked potentials (AEPs) were recorded during echolocation in a false killer whale Pseudorca crassidens. An electronically synthesized and played-back ("phantom") echo was used. Each electronic echo was triggered by an emitted biosonar pulse. The echo had a spectrum similar to that of the emitted biosonar clicks, and its intensity was proportional to that of the emitted click. The attenuation of the echo relative to the emitted click and its delay was controlled by the experimenter. Four combinations of echo attenuation and delay were tested (-31 dB, 2 ms), (-40 dB, 4 ms), (-49 dB, 8 ms), and (-58 dB, 16 ms); thus, attenuation and delay were associated with a rate of 9 dB of increased attenuation per delay doubling. AEPs related to emitted clicks displayed a regular amplitude dependence on the click level. Echo-related AEPs did not feature amplitude dependence on echo attenuation or emitted click levels, except in a few combinations of the lowest values of these two variables. The results are explained by a hypothesis that partial forward masking of the echoes by the preceding emitted sonar pulses serves as a kind of automatic gain control in the auditory system of echolocating odontocetes.
Novel all-optical logic gate using an add/drop filter and intensity switch.
Threepak, T; Mitatha, S; Yupapin, P P
2011-12-01
A novel design of all-optical logic device is proposed. An all-optical logic device system composes of an optical intensity switch and add/drop filter. The intensity switch is formed to switch signal by using the relationship between refraction angle and signal intensity. In operation, two input signals are coupled into one with some coupling loss and attenuation, in which the combination of add/drop with intensity switch produces the optical logic gate. The advantage is that the proposed device can operate the high speed logic function. Moreover, it uses low power consumption. Furthermore, by using the extremely small component, this design can be put into a single chip. Finally, we have successfully produced the all-optical logic gate that can generate the accurate AND and NOT operation results.
Coombs, Catherine; Kuk, Deborah; Devlin, Sean; Siegelbaum, Robert H; Durack, Jeremy C; Parameswaran, Rekha; Mantha, Simon; Deng, Kathy; Soff, Gerald
2017-11-01
Venous thromboembolism (VTE) is a common complication in cancer patients and anticoagulation (AC) remains the standard of care for treatment. Inferior vena cava (IVC) filters may also used to reduce the risk of pulmonary embolism, either alone or in addition to AC. Although widely used, data are limited on the safety and efficacy of IVC filters in cancer patients. We performed a retrospective review of outcomes after IVC filter insertion in a database of 1270 consecutive patients with cancer-associated pulmonary embolism (PE) at our institution between 2008 and 2009. Outcomes measured included rate of all recurrent VTE, recurrent PE, and overall survival within 12 months. 317 (25%) of the 1270 patients with PE had IVC filters placed within 30 days of the index PE event or prior to the index PE in the setting of prior DVT. Patients with IVC filters had markedly lower overall survival (7.3 months) than the non-IVC filter patients (13.2 months). Filter patients also had a lower rate of AC use at time of initial PE. There was a trend towards higher recurrent VTE in patients with IVC filters (11.9%) compared to non-filter patients (7.7%), but this was not significant (p = 0.086). The risk of recurrent PE was similar between the IVC filter cohort (3.5%) and non-filter group (3.5%, p = 0.99). Cancer patients receiving IVC filters had a similar risk of recurrent PE, but a trend towards more overall recurrent VTE. The filter patients had poorer overall survival, which may reflect a poorer cancer prognosis, and had greater contraindication to AC; therefore these patients likely had a higher inherent risk for recurrent VTE. A prospective study would be helpful for further clarification on the partial reduction in the recurrent PE risk by IVC filter placement in cancer patients.
Advanced Wireless Integrated Navy Network (AWINN)
2005-12-31
handle high data rates using COTS FPGAs . The effort of the Cross-Layer Optimization group is focused on cross-layer design of UWB for position location...From Transmitter Boar1 To Receiver BoardTransmittedl Receiver i i.. Switch Lowpass -20 dB FPGA -2dB Filter Gain Controlled Gain Variable Attenuator... FPGA Code * April - June 2006 "o Demonstrate Transceiver Operation "o Integrate Transceiver with Other AWINN Activities Personnel: Chris R. Anderson
2009-06-01
Filters, Order 3, Type 0-C, Optional Range B.2.2 Sound Level Meter Calibration • ISO / IEC 17025 :2005 General requirements for the competence of...noise levels − NCSL -National Conference of Standards Laboratories − ISO - International Standards Organization − IEC - The International...testing and calibration laboratories • ISO 10012:2003 Measurement management systems -- Requirements for measurement processes and measuring
Antimicrobial Efficiency of Iodinated Individual Protection Filters
2004-11-01
additional 2 logs of attenuation vs. a standard COTS canister when challenged with MS2 coliphage . U U U UU 9 Joseph D. Wander 850-283-6240 NOTICES USING...versus a standard COTS canister when challenged with MS2 coliphage . INTRODUCTION Biological weapons are not new, and have been used as warfare...canisters and the iodinated clip-on prototypes were challenged with aerosolized MS2 coliphage . EXPERIMENTAL METHODS Escherichia coli (ATCC 15597) was
The Structure of Processing Resource Demands in Monitoring Automatic Systems.
1981-01-01
Attempts at modelling the human failure detection process have continually focused on normative predictions of optimal operator behavior ( Smallwood ...Broadbent’s filter model (Broadbent, 1957), to Treisman’s attenuation model (Treisman, 1964), to Norman’s late selection model ( Norman , 1968), tife concept...survey and a model. Acta Psychologica, 1967, 27, 84-92. Moray, N. Mental workload: Its theory and measurement. New York: Plenum Press, 1979. Li 42 Norman
Sun-Direction Estimation Using a Partially Underdetermined Set of Coarse Sun Sensors
NASA Astrophysics Data System (ADS)
O'Keefe, Stephen A.; Schaub, Hanspeter
2015-09-01
A comparison of different methods to estimate the sun-direction vector using a partially underdetermined set of cosine-type coarse sun sensors (CSS), while simultaneously controlling the attitude towards a power-positive orientation, is presented. CSS are commonly used in performing power-positive sun-pointing and are attractive due to their relative inexpensiveness, small size, and reduced power consumption. For this study only CSS and rate gyro measurements are available, and the sensor configuration does not provide global triple coverage required for a unique sun-direction calculation. The methods investigated include a vector average method, a combination of least squares and minimum norm criteria, and an extended Kalman filter approach. All cases are formulated such that precise ground calibration of the CSS is not required. Despite significant biases in the state dynamics and measurement models, Monte Carlo simulations show that an extended Kalman filter approach, despite the underdetermined sensor coverage, can provide degree-level accuracy of the sun-direction vector both with and without a control algorithm running simultaneously. If no rate gyro measurements are available, and rates are partially estimated from CSS, the EKF performance degrades as expected, but is still able to achieve better than 10∘ accuracy using only CSS measurements.
Low-frequency dispersion and attenuation in anisotropic partially saturated rocks
NASA Astrophysics Data System (ADS)
Cavallini, Fabio; Carcione, José M.; Vidal de Ventós, Daniel; Engell-Sørensen, Lisbeth
2017-06-01
The mesoscopic-loss mechanism is believed to be the most important attenuation mechanism in porous media at seismic frequencies. It is caused by P-wave conversion to slow diffusion (Biot) modes at material inhomogeneity on length scales of the order of centimetres. It is very effective in partially saturated media, particularly in the presence of gas. We explicitly extend the theory of wave propagation at normal incidence to three periodic thin layers and using this result we obtain the five complex and frequency-dependent stiffness components of the corresponding periodic finely layered medium, where the equivalent medium is anisotropic, specifically transversely isotropic. The relaxation behaviour can be described by a single complex and frequency-dependent stiffness component, since the medium consists of plane homogeneous layers. The media can be dissimilar in any property, but a relevant example in hydrocarbon exploration is the case of partial saturation and the same frame skeleton, where the fluid can be brine, oil and gas. The numerical examples illustrate the implementation of the theory to compute the wave velocities (phase and energy) and quality factors. We consider two main cases, namely, the same frame (or skeleton) and different fluids, and the same fluid and different frame properties. Unlike the two-phase case (two fluids), the results show two relaxation peaks. This scenario is more realistic since usually reservoirs rocks contain oil, brine and gas. The theory is quite general since it is not only restricted to partial saturation, but also applies to important properties such as porosity and permeability heterogeneities.
Unenhanced third-generation dual-source chest CT using a tin filter for spectral shaping at 100kVp.
Haubenreisser, Holger; Meyer, Mathias; Sudarski, Sonja; Allmendinger, Thomas; Schoenberg, Stefan O; Henzler, Thomas
2015-08-01
To prospectively investigate image quality and radiation dose of 100kVp spectral shaping chest CT using a dedicated tin filter on a 3rd generation dual-source CT (DSCT) in comparison to standard 100kVp chest CT. Sixty patients referred for a non-contrast chest on a 3rd generation DSCT were prospectively included and examined at 100kVp with a dedicated tin filter. These patients were retrospectively matched with patients that were examined on a 2nd generation DSCT at 100kVp without tin filter. Objective and subjective image quality was assessed in various anatomic regions and radiation dose was compared. Radiation dose was decreased by 90% using the tin filter (3.0 vs 0.32mSv). Soft tissue attenuation and image noise was not statistically different for both examination techniques (p>0.05), however image noise was found to be significantly higher in the trachea when using the additional tin filter (p=0.002). SNR was found to be statistically similar in pulmonary tissue, significantly lower when measured in air and significantly higher in the aorta for the scans on the 3rd generation DSCT. Subjective image quality with regard to overall quality and image noise and sharpness was not statistically significantly different (p>0.05). 100kVp spectral shaping chest CT by means of a tube-based tin-filter on a 3rd generation DSCT allows 90% dose reduction when compared to 100kVp chest CT on a 2nd generation DSCT without spectral shaping. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
Kalra, Mannudeep K; Maher, Michael M; Blake, Michael A; Lucey, Brian C; Karau, Kelly; Toth, Thomas L; Avinash, Gopal; Halpern, Elkan F; Saini, Sanjay
2004-09-01
To assess the effect of noise reduction filters on detection and characterization of lesions on low-radiation-dose abdominal computed tomographic (CT) images. Low-dose CT images of abdominal lesions in 19 consecutive patients (11 women, eight men; age range, 32-78 years) were obtained at reduced tube currents (120-144 mAs). These baseline low-dose CT images were postprocessed with six noise reduction filters; the resulting postprocessed images were then randomly assorted with baseline images. Three radiologists performed independent evaluation of randomized images for presence, number, margins, attenuation, conspicuity, calcification, and enhancement of lesions, as well as image noise. Side-by-side comparison of baseline images with postprocessed images was performed by using a five-point scale for assessing lesion conspicuity and margins, image noise, beam hardening, and diagnostic acceptability. Quantitative noise and contrast-to-noise ratio were obtained for all liver lesions. Statistical analysis was performed by using the Wilcoxon signed rank test, Student t test, and kappa test of agreement. Significant reduction of noise was observed in images postprocessed with filter F compared with the noise in baseline nonfiltered images (P =.004). Although the number of lesions seen on baseline images and that seen on postprocessed images were identical, lesions were less conspicuous on postprocessed images than on baseline images. A decrease in quantitative image noise and contrast-to-noise ratio for liver lesions was noted with all noise reduction filters. There was good interobserver agreement (kappa = 0.7). Although the use of currently available noise reduction filters improves image noise and ameliorates beam-hardening artifacts at low-dose CT, such filters are limited by a compromise in lesion conspicuity and appearance in comparison with lesion conspicuity and appearance on baseline low-dose CT images. Copyright RSNA, 2004
Huber, Maximilian; Hilbig, Harald; Badenberg, Sophia C; Fassnacht, Julius; Drewes, Jörg E; Helmreich, Brigitte
2016-10-01
The objective of this research study was to elucidate the removal and remobilization behaviors of five heavy metals (i.e., Cd, Cu, Ni, Pb, and Zn) that had been fixed onto sorptive filter materials used in decentralized stormwater treatment systems receiving traffic area runoff. Six filter materials (i.e., granular activated carbon, a mixture of granular activated alumina and porous concrete, granular activated lignite, half-burnt dolomite, and two granular ferric hydroxides) were evaluated in column experiments. First, a simultaneous preloading with the heavy metals was performed for each filter material. Subsequently, the remobilization effect was tested by three de-icing salt experiments in duplicate using pure NaCl, a mixture of NaCl and CaCl2, and a mixture of NaCl and MgCl2. Three layers of each column were separated to specify the attenuation of heavy metals as a function of depth. Cu and Pb were retained best by most of the selected filter materials, and Cu was often released the least of all metals by the three de-icing salts. The mixture of NaCl and CaCl2 resulted in a stronger effect upon remobilization than the other two de-icing salts. For the material with the highest retention, the effect of the preloading level upon remobilization was measured. The removal mechanisms of all filter materials were determined by advanced laboratory methods. For example, the different intrusions of heavy metals into the particles were determined. Findings of this study can result in improved filter materials used in decentralized stormwater treatment systems. Copyright © 2016 Elsevier Ltd. All rights reserved.
Kim, Hyun Nam; Lee, Ju Hyuk; Park, Han Beom; Kim, Hyun Jin; Cho, Sung Oh
2018-01-01
We designed and fabricated a surface applicator of a novel carbon nanotube (CNT)-based miniature X-ray tube for the use in superficial electronic brachytherapy of skin cancer. To investigate the effectiveness of the surface applicator, the performance of the applicator was numerically and experimentally analyzed. The surface applicator consists of a graphite flattening filter and an X-ray shield. A Monte Carlo radiation transport code, MCNP6, was used to optimize the geometries of both the flattening filter and the shield so that X-rays are generated uniformly over the desired region. The performance of the graphite filter was compared with that of conventional aluminum (Al) filters of different geometries using the numerical simulations. After fabricating a surface applicator, the X-ray spatial distribution was measured to evaluate the performance of the applicator. The graphite filter shows better spatial dose uniformity and less dose distortion than Al filters. Moreover, graphite allows easy fabrication of the flattening filter due to its low X-ray attenuation property, which is particularly important for low-energy electronic brachytherapy. The applicator also shows that no further X-ray shielding is required for the application because unwanted X-rays are completely protected. As a result, highly uniform X-ray dose distribution was achieved from the miniature X-ray tube mounted with the surface applicators. The measured values of both flatness and symmetry were less than 5% and the measured penumbra values were less than 1 mm. All these values satisfy the currently accepted tolerance criteria for radiation therapy. The surface applicator exhibits sufficient performance capability for their application in electronic brachytherapy of skin cancers. © 2017 American Association of Physicists in Medicine.
Gottlieb, Daniel A
2006-03-01
Partial reinforcement often leads to asymptotically higher rates of responding and number of trials with a response than does continuous reinforcement in pigeon autoshaping. However, comparisons typically involve a partial reinforcement schedule that differs from the continuous reinforcement schedule in both time between reinforced trials and probability of reinforcement. Two experiments examined the relative contributions of these two manipulations to asymptotic response rate. Results suggest that the greater responding previously seen with partial reinforcement is primarily due to differential probability of reinforcement and not differential time between reinforced trials. Further, once established, differences in responding are resistant to a change in stimulus and contingency. Secondary response theories of autoshaped responding (theories that posit additional response-augmenting or response-attenuating mechanisms specific to partial or continuous reinforcement) cannot fully accommodate the current body of data. It is suggested that researchers who study pigeon autoshaping train animals on a common task prior to training them under different conditions.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Viswanathan, Sandeep; Rothamer, David; Zelenyuk, Alla
The impact of inlet particle properties on the filtration performance of clean and particulate matter (PM) laden cordierite filter samples was evaluated using PM generated by a spark-ignition direct-injection (SIDI) engine fuelled with tier II EEE certification gasoline. Prior to the filtration experiments, a scanning mobility particle spectrometer (SMPS) was used to measure the electrical-mobility based particle size distribution (PSD) in the SIDI exhaust from distinct engine operating conditions. An advanced aerosol characterization system that comprised of a centrifugal particle mass analyser (CPMA), a differential mobility analyser (DMA), and a single particle mass spectrometer (SPLAT II) was used to obtainmore » additional information on the SIDI particulate, including particle composition, mass, and dynamic shape factors (DSFs) in the transition () and free-molecular () flow regimes. During the filtration experiments, real-time measurements of PSDs upstream and downstream of the filter sample were used to estimate the filtration performance and the total trapped mass within the filter using an integrated particle size distribution method. The filter loading process was paused multiple times to evaluate the filtration performance in the partially loaded state. The change in vacuum aerodynamic diameter () distribution of mass-selected particles was examined for flow through the filter to identify whether preferential capture of particles of certain shapes occurred in the filter. The filter was also probed using different inlet PSDs to understand their impact on particle capture within the filter sample. Results from the filtration experiment suggest that pausing the filter loading process and subsequently performing the filter probing experiments did not impact the overall evolution of filtration performance. Within the present distribution of particle sizes, filter efficiency was independent of particle shape potentially due to the diffusion-dominant filtration process. Particle mobility diameter and trapped mass within the filter appeared to be the dominant parameters that impacted filter performance.« less
Erythemal irradiances of filtered ultraviolet radiation
NASA Astrophysics Data System (ADS)
Parisi, A. V.; Wong, J. C. F.
1997-07-01
A spectrum evaluator
employing four passive dosimeters has been used to evaluate the time averaged spectrum to allow calculation of the erythemal exposures resulting from the predominantly UVA component of filtered solar ultraviolet radiation. An exposure interval of approximately 20 min to autumn and spring sunshine was required for the spectrum evaluator to allow evaluation of the filtered source spectrum. For a clear spring day an erythemal exposure of 0.85 MED (minimum erythemal dose) to a horizontal plane and 0.38 MED to a vertical plane over a 6 h period was measured within a glass enclosure. For a partially cloudy day six weeks later, these were 0.89 and 0.44 MED for the horizontal and the vertical planes respectively. The ratios of the filtered to the unfiltered erythemal exposures within and outside the enclosure respectively ranged from 0.08 to 0.18 throughout the two days.
Improved hybrid information filtering based on limited time window
NASA Astrophysics Data System (ADS)
Song, Wen-Jun; Guo, Qiang; Liu, Jian-Guo
2014-12-01
Adopting the entire collecting information of users, the hybrid information filtering of heat conduction and mass diffusion (HHM) (Zhou et al., 2010) was successfully proposed to solve the apparent diversity-accuracy dilemma. Since the recent behaviors are more effective to capture the users' potential interests, we present an improved hybrid information filtering of adopting the partial recent information. We expand the time window to generate a series of training sets, each of which is treated as known information to predict the future links proven by the testing set. The experimental results on one benchmark dataset Netflix indicate that by only using approximately 31% recent rating records, the accuracy could be improved by an average of 4.22% and the diversity could be improved by 13.74%. In addition, the performance on the dataset MovieLens could be preserved by considering approximately 60% recent records. Furthermore, we find that the improved algorithm is effective to solve the cold-start problem. This work could improve the information filtering performance and shorten the computational time.
Image reconstruction from cone-beam projections with attenuation correction
NASA Astrophysics Data System (ADS)
Weng, Yi
1997-07-01
In single photon emission computered tomography (SPECT) imaging, photon attenuation within the body is a major factor contributing to the quantitative inaccuracy in measuring the distribution of radioactivity. Cone-beam SPECT provides improved sensitivity for imaging small organs. This thesis extends the results for 2D parallel- beam and fan-beam geometry to 3D parallel-beam and cone- beam geometries in order to derive filtered backprojection reconstruction algorithms for the 3D exponential parallel-beam transform and for the exponential cone-beam transform with sampling on a sphere. An exact inversion formula for the 3D exponential parallel-beam transform is obtained and is extended to the 3D exponential cone-beam transform. Sampling on a sphere is not useful clinically and current cone-beam tomography, with the focal point traversing a planar orbit, does not acquire sufficient data to give an accurate reconstruction. Thus a data acquisition method that obtains complete data for cone-beam SPECT by simultaneously rotating the gamma camera and translating the patient bed, so that cone-beam projections can be obtained with the focal point traversing a helix that surrounds the patient was developed. First, an implementation of Grangeat's algorithm for helical cone- beam projections was developed without attenuation correction. A fast new rebinning scheme was developed that uses all of the detected data to reconstruct the image and properly normalizes any multiply scanned data. In the case of attenuation no theorem analogous to Tuy's has been proven. We hypothesized that an artifact-free reconstruction could be obtained even if the cone-beam data are attenuated, provided the imaging orbit satisfies Tuy's condition and the exact attenuation map is known. Cone-beam emission data were acquired by using a circle- and-line and a helix orbit on a clinical SPECT system. An iterative conjugate gradient reconstruction algorithm was used to reconstruct projection data with a known attenuation map. The quantitative accuracy of the attenuation-corrected emission reconstruction was significantly improved.
2013-01-01
β-Adrenoceptor antagonists boast a 50-year use for symptomatic control in numerous cardiovascular diseases. One might expect highly selective antagonists are available for the human β-adrenoceptor subtype involved in these diseases, yet few truly β1-selective molecules exist. To address this clinical need, we re-evaluated LK 204-545 (1),1 a selective β1-adrenoceptor antagonist, and discovered it possessed significant partial agonism. Removal of 1’s aromatic nitrile afforded 19, a ligand with similar β1-adrenoceptor selectivity and partial agonism (log KD of −7.75 and −5.15 as an antagonist of functional β1- and β2-mediated responses, respectively, and 34% of the maximal response of isoprenaline (β1)). In vitro β-adrenoceptor selectivity and partial agonism of 19 were mirrored in vivo. We designed analogues of 19 to improve affinity, selectivity, and partial agonism. Although partial agonism could not be fully attenuated, SAR suggests that an extended alkoxyalkoxy side chain, alongside substituents at the meta- or para-positions of the phenylurea, increases ligand affinity and β1-selectivity. PMID:23614528
Ishizawa, Yoshiki; Dobashi, Suguru; Kadoya, Noriyuki; Ito, Kengo; Chiba, Takahito; Takayama, Yoshiki; Sato, Kiyokazu; Takeda, Ken
2018-05-17
An accurate source model of a medical linear accelerator is essential for Monte Carlo (MC) dose calculations. This study aims to propose an analytical photon source model based on particle transport in parameterized accelerator structures, focusing on a more realistic determination of linac photon spectra compared to existing approaches. We designed the primary and secondary photon sources based on the photons attenuated and scattered by a parameterized flattening filter. The primary photons were derived by attenuating bremsstrahlung photons based on the path length in the filter. Conversely, the secondary photons were derived from the decrement of the primary photons in the attenuation process. This design facilitates these sources to share the free parameters of the filter shape and be related to each other through the photon interaction in the filter. We introduced two other parameters of the primary photon source to describe the particle fluence in penumbral regions. All the parameters are optimized based on calculated dose curves in water using the pencil-beam-based algorithm. To verify the modeling accuracy, we compared the proposed model with the phase space data (PSD) of the Varian TrueBeam 6 and 15 MV accelerators in terms of the beam characteristics and the dose distributions. The EGS5 Monte Carlo code was used to calculate the dose distributions associated with the optimized model and reference PSD in a homogeneous water phantom and a heterogeneous lung phantom. We calculated the percentage of points passing 1D and 2D gamma analysis with 1%/1 mm criteria for the dose curves and lateral dose distributions, respectively. The optimized model accurately reproduced the spectral curves of the reference PSD both on- and off-axis. The depth dose and lateral dose profiles of the optimized model also showed good agreement with those of the reference PSD. The passing rates of the 1D gamma analysis with 1%/1 mm criteria between the model and PSD were 100% for 4 × 4, 10 × 10, and 20 × 20 cm 2 fields at multiple depths. For the 2D dose distributions calculated in the heterogeneous lung phantom, the 2D gamma pass rate was 100% for 6 and 15 MV beams. The model optimization time was less than 4 min. The proposed source model optimization process accurately produces photon fluence spectra from a linac using valid physical properties, without detailed knowledge of the geometry of the linac head, and with minimal optimization time. © 2018 American Association of Physicists in Medicine.
Sanchez, Sophie; Fernandez, Vincent; Pierce, Stephanie E; Tafforeau, Paul
2013-09-01
Propagation phase-contrast synchrotron radiation microtomography (PPC-SRμCT) has proved to be very successful for examining fossils. Because fossils range widely in taphonomic preservation, size, shape and density, X-ray computed tomography protocols are constantly being developed and refined. Here we present a 1-h procedure that combines a filtered high-energy polychromatic beam with long-distance PPC-SRμCT (sample to detector: 4-16 m) and an attenuation protocol normalizing the absorption profile (tested on 13-cm-thick and 5.242 g cm(-3) locally dense samples but applicable to 20-cm-thick samples). This approach provides high-quality imaging results, which show marked improvement relative to results from images obtained without the attenuation protocol in apparent transmission, contrast and signal-to-noise ratio. The attenuation protocol involves immersing samples in a tube filled with aluminum or glass balls in association with a U-shaped aluminum profiler. This technique therefore provides access to a larger dynamic range of the detector used for tomographic reconstruction. This protocol homogenizes beam-hardening artifacts, thereby rendering it effective for use with conventional μCT scanners.
Corollary discharge provides the sensory content of inner speech.
Scott, Mark
2013-09-01
Inner speech is one of the most common, but least investigated, mental activities humans perform. It is an internal copy of one's external voice and so is similar to a well-established component of motor control: corollary discharge. Corollary discharge is a prediction of the sound of one's voice generated by the motor system. This prediction is normally used to filter self-caused sounds from perception, which segregates them from externally caused sounds and prevents the sensory confusion that would otherwise result. The similarity between inner speech and corollary discharge motivates the theory, tested here, that corollary discharge provides the sensory content of inner speech. The results reported here show that inner speech attenuates the impact of external sounds. This attenuation was measured using a context effect (an influence of contextual speech sounds on the perception of subsequent speech sounds), which weakens in the presence of speech imagery that matches the context sound. Results from a control experiment demonstrated this weakening in external speech as well. Such sensory attenuation is a hallmark of corollary discharge.
NASA Astrophysics Data System (ADS)
Jang, Sunyoung; Jaszczak, R. J.; Tsui, B. M. W.; Metz, C. E.; Gilland, D. R.; Turkington, T. G.; Coleman, R. E.
1998-08-01
The purpose of this work was to evaluate lesion detectability with and without nonuniform attenuation compensation (AC) in myocardial perfusion SPECT imaging in women using an anthropomorphic phantom and receiver operating characteristics (ROC) methodology. Breast attenuation causes artifacts in reconstructed images and may increase the difficulty of diagnosis of myocardial perfusion imaging in women. The null hypothesis tested using the ROC study was that nonuniform AC does not change the lesion detectability in myocardial perfusion SPECT imaging in women. The authors used a filtered backprojection (FBP) reconstruction algorithm and Chang's (1978) single iteration method for AC. In conclusion, with the authors' proposed myocardial defect model nuclear medicine physicians demonstrated no significant difference for the detection of the anterior wall defect; however, a greater accuracy for the detection of the inferior wall defect was observed without nonuniform AC than with it (P-value=0.0034). Medical physicists did not demonstrate any statistically significant difference in defect detection accuracy with or without nonuniform AC in the female phantom.
Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import.
Götz, Veronika; Magar, Linda; Dornfeld, Dominik; Giese, Sebastian; Pohlmann, Anne; Höper, Dirk; Kong, Byung-Whi; Jans, David A; Beer, Martin; Haller, Otto; Schwemmle, Martin
2016-03-18
To establish a new lineage in the human population, avian influenza A viruses (AIV) must overcome the intracellular restriction factor MxA. Partial escape from MxA restriction can be achieved when the viral nucleoprotein (NP) acquires the critical human-adaptive amino acid residues 100I/V, 283P, and 313Y. Here, we show that introduction of these three residues into the NP of an avian H5N1 virus renders it genetically unstable, resulting in viruses harboring additional single mutations, including G16D. These substitutions restored genetic stability yet again yielded viruses with varying degrees of attenuation in mammalian and avian cells. Additionally, most of the mutant viruses lost the capacity to escape MxA restriction, with the exception of the G16D virus. We show that MxA escape is linked to attenuation by demonstrating that the three substitutions promoting MxA escape disturbed intracellular trafficking of incoming viral ribonucleoprotein complexes (vRNPs), thereby resulting in impaired nuclear import, and that the additional acquired mutations only partially compensate for this import block. We conclude that for adaptation to the human host, AIV must not only overcome MxA restriction but also an associated block in nuclear vRNP import. This inherent difficulty may partially explain the frequent failure of AIV to become pandemic.
Wave speed propagation measurements on highly attenuative heated materials
Moore, David G.; Ober, Curtis C.; Rodacy, Phil J.; ...
2015-09-19
Ultrasonic wave propagation decreases as a material is heated. Two factors that can characterize material properties are changes in wave speed and energy loss from interactions within the media. Relatively small variations in velocity and attenuation can detect significant differences in microstructures. This paper discusses an overview of experimental techniques that document the changes within a highly attenuative material as it is either being heated or cooled from 25°C to 90°C. The experimental set-up utilizes ultrasonic probes in a through-transmission configuration. The waveforms are recorded and analyzed during thermal experiments. To complement the ultrasonic data, a Discontinuous-Galerkin Model (DGM) wasmore » also created which uses unstructured meshes and documents how waves travel in these anisotropic media. This numerical method solves particle motion travel using partial differential equations and outputs a wave trace per unit time. As a result, both experimental and analytical data are compared and presented.« less
NASA Astrophysics Data System (ADS)
Haberland, Christian; Rietbrock, Andreas
2001-06-01
High-quality data from 1498 local earthquakes recorded by the PISCO '94 (Proyecto de Investigatión Sismológica de la Cordillera Occidental, 1994) and ANCORP '96 (Andean Continental Research Project, 1996) temporary seismological networks allowed the detailed determination of the three-dimensional (3-D) attenuation structure (Qp-1) beneath the recent magmatic arc in the western central Andes (20° to 24°S). Assuming a frequency-independent Qp-1 in a frequency band between 1 and 30 Hz, whole path attenuation (t*) was estimated from the amplitude spectra of the P waves using spectral ratios and a spectral inversion technique. The damped least squares inversion (tomography) of the data reveals a complex attenuation structure. Crust and mantle of the forearc and subducting slab are generally characterized by low attenuation (Qp > 1000). Crust and mantle beneath the magmatic arc show elevated attenuation. The strongest anomaly of extremely low Qp is found in the crust between 22° and 23°S beneath the recent volcanic arc (Qp < 100). N-S variations can be observed: The western flank of the crustal attenuation anomaly follows the curved course of the volcanic front. North of 21°S the attenuation is less developed. In the northern part of the study area the low-Qp zone penetrates in the forearc mantle down to the subducting slab. In the south a deeper zone of high attenuation is resolved between 23° and 24°S directly above the subducting slab. Low Qp in the mantle correlates with earthquake clusters. The strong crustal attenuation is confined to the distribution of young ignimbrites and silicic volcanism and is interpreted as a thermally weakened zone with partial melts. The attenuation pattern in the upper mantle might reflect the variable extent of the asthenosphere and maps variations of subduction-related hydration processes in the mantle wedge from slab-derived fluids.
Mizuno, Tooru M; Kelley, Kevin A; Pasinetti, Giulio M; Roberts, James L; Mobbs, Charles V
2003-11-01
Hypothalamic proopiomelanocortin (POMC) gene expression is reduced in many forms of obesity and diabetes, particularly in those attributable to deficiencies in leptin or its receptor. To assess the functional significance of POMC in mediating metabolic phenotypes associated with leptin deficiency, leptin-deficient mice bearing a transgene expressing the POMC gene under control of the neuron-specific enolase promoter were produced. The POMC transgene attenuated fasting-induced hyperphagia in wild-type mice. Furthermore, the POMC transgene partially reversed obesity, hyperphagia, and hypothermia and effectively normalized hyperglycemia, glucosuria, glucose intolerance, and insulin resistance in leptin-deficient mice. Effects of the POMC transgene on glucose homeostasis were independent of the partial correction of hyperphagia and obesity. Furthermore, the POMC transgene normalized the profile of hepatic and adipose gene expression associated with gluconeogenesis, glucose output, and insulin sensitivity. These results indicate that central POMC is a key modulator of glucose homeostasis and that agonists of POMC products may provide effective therapy in treating impairments in glucose homeostasis when hypothalamic POMC expression is reduced, as occurs with leptin deficiency, hypothalamic damage, and aging.
Uludag, K; Kohl, M; Steinbrink, J; Obrig, H; Villringer, A
2002-01-01
Using the modified Lambert-Beer law to analyze attenuation changes measured noninvasively during functional activation of the brain might result in an insufficient separation of chromophore changes ("cross talk") due to the wavelength dependence of the partial path length of photons in the activated volume of the head. The partial path length was estimated by performing Monte Carlo simulations on layered head models. When assuming cortical activation (e.g., in the depth of 8-12 mm), we determine negligible cross talk when considering changes in oxygenated and deoxygenated hemoglobin. But additionally taking changes in the redox state of cytochrome-c-oxidase into account, this analysis results in significant artifacts. An analysis developed for changes in mean time of flight--instead of changes in attenuation--reduces the cross talk for the layers of cortical activation. These results were validated for different oxygen saturations, wavelength combinations and scattering coefficients. For the analysis of changes in oxygenated and deoxygenated hemoglobin only, low cross talk was also found when the activated volume was assumed to be a 4-mm-diam sphere.
Yadav, Ram Bharos; Srivastava, Subodh; Srivastava, Rajeev
2016-01-01
The proposed framework is obtained by casting the noise removal problem into a variational framework. This framework automatically identifies the various types of noise present in the magnetic resonance image and filters them by choosing an appropriate filter. This filter includes two terms: the first term is a data likelihood term and the second term is a prior function. The first term is obtained by minimizing the negative log likelihood of the corresponding probability density functions: Gaussian or Rayleigh or Rician. Further, due to the ill-posedness of the likelihood term, a prior function is needed. This paper examines three partial differential equation based priors which include total variation based prior, anisotropic diffusion based prior, and a complex diffusion (CD) based prior. A regularization parameter is used to balance the trade-off between data fidelity term and prior. The finite difference scheme is used for discretization of the proposed method. The performance analysis and comparative study of the proposed method with other standard methods is presented for brain web dataset at varying noise levels in terms of peak signal-to-noise ratio, mean square error, structure similarity index map, and correlation parameter. From the simulation results, it is observed that the proposed framework with CD based prior is performing better in comparison to other priors in consideration.
NASA Astrophysics Data System (ADS)
Singh, Japneet; Gaskell, Martin; Gill, Jake
2017-01-01
We use mid-IR (WIRE), optical (SDSS), and ultraviolet (GALEX) photometry of over 80,000 AGNs to derive mean attenuation curves from the optical to the rest frame extreme ultraviolet (EUV) for (i) “normal” AGN dust dominating the optical reddening of AGNs and (ii) “BAL dust” - the dust causing the additional extinction in AGNs observed to have broad absorption lines (BALs). Our method confirms that the attenuation curve of “normal” AGN dust is flat in the ultraviolet, as found by Gaskell et al. (2004). In striking contrast to this, the attenuation curve for BAL dust is well fit by a steeply-rising, SMC-like curve. We confirm the shape of the theoretical Weingartner & Draine (2001) SMC curve out to 700 Angstroms but the drop in attenuation to still shorter wavelengths (400 Angstroms) seems to be less than predicted. We find identical attenuation curves for high-ionization and low-ionization BALQSOs. We suggest that attenuation curves appearing to be steeper than the SMC are due to differences in underlying spectra and partial covering by BAL dust. This work was This work was performed under the auspices of the Science Internship Program (SIP) of the University of California at Santa Cruz performed under the auspices of the Science Internship Program (SIP) of the University of California at Santa Cruz.
LES with and without explicit filtering: comparison and assessment of various models
NASA Astrophysics Data System (ADS)
Winckelmans, Gregoire S.; Jeanmart, Herve; Wray, Alan A.; Carati, Daniele
2000-11-01
The proper mathematical formalism for large eddy simulation (LES) of turbulent flows assumes that a regular ``explicit" filter (i.e., a filter with a well-defined second moment, such as the gaussian, the top hat, etc.) is applied to the equations of fluid motion. This filter is then responsible for a ``filtered-scale" stress. Because of the discretization of the filtered equations, using the LES grid, there is also a ``subgrid-scale" stress. The global effective stress is found to be the discretization of a filtered-scale stress plus a subgrid-scale stress. The former can be partially reconstructed from an exact, infinite, series, the first term of which is the ``tensor-diffusivity" model of Leonard and is found, in practice, to be sufficient for modeling. Alternatively, sufficient reconstruction can also be achieved using the ``scale-similarity" model of Bardina. The latter corresponds to loss of information: it cannot be reconstructed; its effect (essentially dissipation) must be modeled using ad hoc modeling strategies (such as the dynamic version of the ``effective viscosity" model of Smagorinsky). Practitionners also often assume LES without explicit filtering: the effective stress is then only a subgrid-scale stress. We here compare the performance of various LES models for both approaches (with and without explicit filtering), and for cases without solid boundaries: (1) decay of isotropic turbulence; (2) decay of aircraft wake vortices in a turbulent atmosphere. One main conclusion is that better subgrid-scale models are still needed, the effective viscosity models being too active at the large scales.
Collaborative emitter tracking using Rao-Blackwellized random exchange diffusion particle filtering
NASA Astrophysics Data System (ADS)
Bruno, Marcelo G. S.; Dias, Stiven S.
2014-12-01
We introduce in this paper the fully distributed, random exchange diffusion particle filter (ReDif-PF) to track a moving emitter using multiple received signal strength (RSS) sensors. We consider scenarios with both known and unknown sensor model parameters. In the unknown parameter case, a Rao-Blackwellized (RB) version of the random exchange diffusion particle filter, referred to as the RB ReDif-PF, is introduced. In a simulated scenario with a partially connected network, the proposed ReDif-PF outperformed a PF tracker that assimilates local neighboring measurements only and also outperformed a linearized random exchange distributed extended Kalman filter (ReDif-EKF). Furthermore, the novel ReDif-PF matched the tracking error performance of alternative suboptimal distributed PFs based respectively on iterative Markov chain move steps and selective average gossiping with an inter-node communication cost that is roughly two orders of magnitude lower than the corresponding cost for the Markov chain and selective gossip filters. Compared to a broadcast-based filter which exactly mimics the optimal centralized tracker or its equivalent (exact) consensus-based implementations, ReDif-PF showed a degradation in steady-state error performance. However, compared to the optimal consensus-based trackers, ReDif-PF is better suited for real-time applications since it does not require iterative inter-node communication between measurement arrivals.
Decentralized stormwater management approaches (e.g., biofiltration swales, pervious pavement, green roofs, rain gardens) that capture, detain, infiltrate, and filter runoff are now commonly used to minimize the impacts of stormwater runoff from impervious surfaces on aquatic eco...
Biochar-amended filter socks reduce herbicide losses via tile line surface inlets
USDA-ARS?s Scientific Manuscript database
Standing water in depressions and behind terraces in fields with subsurface drainage systems can result in reduced crop yields. This concern can be partially alleviated by installing surface inlets that reduce the duration of ponding. Unfortunately, these inlets provide an open conduit for surface w...
USDA-ARS?s Scientific Manuscript database
In multivariate regression analysis of spectroscopy data, spectral preprocessing is often performed to reduce unwanted background information (offsets, sloped baselines) or accentuate absorption features in intrinsically overlapping bands. These procedures, also known as pretreatments, are commonly ...
Petrova, Daniela; Henning, G. Bruce; Stockman, Andrew
2013-01-01
Flickering long-wavelength light appears more yellow than steady light of the same average intensity. The hue change is consistent with distortion of the visual signal at some nonlinear site (or sites) that produces temporal components not present in the original stimulus (known as distortion products). We extracted the temporal attenuation characteristics of the early (prenonlinearity) and late (post-nonlinearity) filter stages in the L- and M-cone chromatic pathway by varying the input stimulus to manipulate the distortion products and the measuring of the observers' sensitivity to them. The early, linear, filter stage acts like a band-pass filter peaking at 10–15 Hz with substantial sensitivity losses at both lower and higher frequencies. Its characteristics are consistent with nonlinearity being early in the visual pathway but following surround inhibition. The late stage, in contrast, acts like a low-pass filter with a cutoff frequency around 3 Hz. The response of the early stage speeds up with radiance, but the late stage does not. A plausible site for the nonlinearity, which modelling suggests may be smoothly compressive but with a hard limit at high input levels, is after surround inhibition from the horizontal cells. PMID:23457358