Implementation of neuromorphic systems: from discrete components to analog VLSI chips (testing and communication issues).

PubMed

Dante, V; Del Giudice, P; Mattia, M

2001-01-01

We review a series of implementations of electronic devices aiming at imitating to some extent structure and function of simple neural systems, with particular emphasis on communication issues. We first provide a short overview of general features of such "neuromorphic" devices and the implications of setting up "tests" for them. We then review the developments directly related to our work at the Istituto Superiore di Sanità (ISS): a pilot electronic neural network implementing a simple classifier, autonomously developing internal representations of incoming stimuli; an output network, collecting information from the previous classifier and extracting the relevant part to be forwarded to the observer; an analog, VLSI (very large scale integration) neural chip implementing a recurrent network of spiking neurons and plastic synapses, and the test setup for it; a board designed to interface the standard PCI (peripheral component interconnect) bus of a PC with a special purpose, asynchronous bus for communication among neuromorphic chips; a short and preliminary account of an application-oriented device, taking advantage of the above communication infrastructure.

A Mobile Robots Experimental Environment with Event-Based Wireless Communication

PubMed Central

Guinaldo, María; Fábregas, Ernesto; Farias, Gonzalo; Dormido-Canto, Sebastián; Chaos, Dictino; Sánchez, José; Dormido, Sebastián

2013-01-01

An experimental platform to communicate between a set of mobile robots through a wireless network has been developed. The mobile robots get their position through a camera which performs as sensor. The video images are processed in a PC and a Waspmote card sends the corresponding position to each robot using the ZigBee standard. A distributed control algorithm based on event-triggered communications has been designed and implemented to bring the robots into the desired formation. Each robot communicates to its neighbors only at event times. Furthermore, a simulation tool has been developed to design and perform experiments with the system. An example of usage is presented. PMID:23881139

A TinyOS-based wireless neural interface.

PubMed

Farshchi, Shahin; Mody, Istvan; Judy, Jack W

2004-01-01

The overlay of a neural interface upon a TinyOS-based sensing and communication platform is described. The system amplifies, digitally encodes, and transmits two EEG channels of neural signals from an un-tethered subject to a remote gateway, which routes the signals to a client PC. This work demonstrates the viability of the TinyOS-based sensor technology as a foundation for chronic remote biological monitoring applications, and thus provides an opportunity to create a system that can leverage from the frequent networking and communications advancements being made by the global TinyOS-development community.

Research of x-ray nondestructive detector for high-speed running conveyor belt with steel wire ropes

NASA Astrophysics Data System (ADS)

Wang, Junfeng; Miao, Changyun; Wang, Wei; Lu, Xiaocui

2008-03-01

An X-ray nondestructive detector for high-speed running conveyor belt with steel wire ropes is researched in the paper. The principle of X-ray nondestructive testing (NDT) is analyzed, the general scheme of the X-ray nondestructive testing system is proposed, and the nondestructive detector for high-speed running conveyor belt with steel wire ropes is developed. The hardware of system is designed with Xilinx's VIRTEX-4 FPGA that embeds PowerPC and MAC IP core, and its network communication software based on TCP/IP protocol is programmed by loading LwIP to PowerPC. The nondestructive testing of high-speed conveyor belt with steel wire ropes and network transfer function are implemented. It is a strong real-time system with rapid scanning speed, high reliability and remotely nondestructive testing function. The nondestructive detector can be applied to the detection of product line in industry.

T-LECS: The Control Software System for MOIRCS

NASA Astrophysics Data System (ADS)

Yoshikawa, T.; Omata, K.; Konishi, M.; Ichikawa, T.; Suzuki, R.; Tokoku, C.; Katsuno, Y.; Nishimura, T.

2006-07-01

MOIRCS (Multi-Object Infrared Camera and Spectrograph) is a new instrument for the Subaru Telescope. We present the system design of the control software system for MOIRCS, named T-LECS (Tohoku University - Layered Electronic Control System). T-LECS is a PC-Linux based network distributed system. Two PCs equipped with the focal plane array system operate two HAWAII2 detectors, respectively, and another PC is used for user interfaces and a database server. Moreover, these PCs control various devices for observations distributed on a TCP/IP network. T-LECS has three interfaces; interfaces to the devices and two user interfaces. One of the user interfaces is to the integrated observation control system (Subaru Observation Software System) for observers, and another one provides the system developers the direct access to the devices of MOIRCS. In order to help the communication between these interfaces, we employ an SQL database system.

Blackmail propagation on small-world networks

NASA Astrophysics Data System (ADS)

Shao, Zhi-Gang; Jian-Ping Sang; Zou, Xian-Wu; Tan, Zhi-Jie; Jin, Zhun-Zhi

2005-06-01

The dynamics of the blackmail propagation model based on small-world networks is investigated. It is found that for a given transmitting probability λ the dynamical behavior of blackmail propagation transits from linear growth type to logistical growth one with the network randomness p increases. The transition takes place at the critical network randomness pc=1/N, where N is the total number of nodes in the network. For a given network randomness p the dynamical behavior of blackmail propagation transits from exponential decrease type to logistical growth one with the transmitting probability λ increases. The transition occurs at the critical transmitting probability λc=1/, where is the average number of the nearest neighbors. The present work will be useful for understanding computer virus epidemics and other spreading phenomena on communication and social networks.

Telemetry Technology

NASA Technical Reports Server (NTRS)

1997-01-01

In 1990, Avtec Systems, Inc. developed its first telemetry boards for Goddard Space Flight Center. Avtec products now include PC/AT, PCI and VME-based high speed I/O boards and turn-key systems. The most recent and most successful technology transfer from NASA to Avtec is the Programmable Telemetry Processor (PTP), a personal computer- based, multi-channel telemetry front-end processing system originally developed to support the NASA communication (NASCOM) network. The PTP performs data acquisition, real-time network transfer, and store and forward operations. There are over 100 PTP systems located in NASA facilities and throughout the world.

Using smart mobile devices in social-network-based health education practice: a learning behavior analysis.

PubMed

Wu, Ting-Ting

2014-06-01

Virtual communities provide numerous resources, immediate feedback, and information sharing, enabling people to rapidly acquire information and knowledge and supporting diverse applications that facilitate interpersonal interactions, communication, and sharing. Moreover, incorporating highly mobile and convenient devices into practice-based courses can be advantageous in learning situations. Therefore, in this study, a tablet PC and Google+ were introduced to a health education practice course to elucidate satisfaction of learning module and conditions and analyze the sequence and frequency of learning behaviors during the social-network-based learning process. According to the analytical results, social networks can improve interaction among peers and between educators and students, particularly when these networks are used to search for data, post articles, engage in discussions, and communicate. In addition, most nursing students and nursing educators expressed a positive attitude and satisfaction toward these innovative teaching methods, and looked forward to continuing the use of this learning approach. Copyright © 2014 Elsevier Ltd. All rights reserved.

Message Passing vs. Shared Address Space on a Cluster of SMPs

NASA Technical Reports Server (NTRS)

Shan, Hongzhang; Singh, Jaswinder Pal; Oliker, Leonid; Biswas, Rupak

2000-01-01

The convergence of scalable computer architectures using clusters of PCs (or PC-SMPs) with commodity networking has become an attractive platform for high end scientific computing. Currently, message-passing and shared address space (SAS) are the two leading programming paradigms for these systems. Message-passing has been standardized with MPI, and is the most common and mature programming approach. However message-passing code development can be extremely difficult, especially for irregular structured computations. SAS offers substantial ease of programming, but may suffer from performance limitations due to poor spatial locality, and high protocol overhead. In this paper, we compare the performance of and programming effort, required for six applications under both programming models on a 32 CPU PC-SMP cluster. Our application suite consists of codes that typically do not exhibit high efficiency under shared memory programming. due to their high communication to computation ratios and complex communication patterns. Results indicate that SAS can achieve about half the parallel efficiency of MPI for most of our applications: however, on certain classes of problems SAS performance is competitive with MPI. We also present new algorithms for improving the PC cluster performance of MPI collective operations.

Integration Of An MR Image Network Into A Clinical PACS

NASA Astrophysics Data System (ADS)

Ratib, Osman M.; Mankovich, Nicholas J.; Taira, Ricky K.; Cho, Paul S.; Huang, H. K.

1988-06-01

A direct link between a clinical pediatric PACS module and a FONAR MRI image network was implemented. The original MR network combines together the MR scanner, a remote viewing station and a central archiving station. The pediatric PACS directly connects to the archiving unit through an Ethernet TCP-IP network adhering to FONAR's protocol. The PACS communication software developed supports the transfer of patient studies and the patient information directly from the MR archive database to the pediatric PACS. In the first phase of our project we developed a package to transfer data between a VAX-111750 and the IBM PC I AT-based MR archive database through the Ethernet network. This system served as a model for PACS-to-modality network communication. Once testing was complete on this research network, the software and network hardware was moved to the clinical pediatric VAX for full PACS integration. In parallel to the direct transmission of digital images to the Pediatric PACS, a broadband communication system in video format was developed for real-time broadcasting of images originating from the MR console to 8 remote viewing stations distributed in the radiology department. These analog viewing stations allow the radiologists to directly monitor patient positioning and to select the scan levels during a patient examination from remote locations in the radiology department. This paper reports (1) the technical details of this implementation, (2) the merits of this network development scheme, and (3) the performance statistics of the network-to-PACS interface.

Management software for a universal device communication controller: application to monitoring and computerized infusions.

PubMed

Coussaert, E J; Cantraine, F R

1996-11-01

We designed a virtual device for a local area network observing, operating and connecting devices to a personal computer. To keep the widest field of application, we proceeded by using abstraction and specification rules of software engineering in the design and implementation of the hardware and software for the Infusion Monitor. We specially built a box of hardware to interface multiple medical instruments with different communication protocols to a PC via a single serial port. We called that box the Universal Device Communication Controller (UDCC). The use of the virtual device driver is illustrated by the Infusion Monitor implemented for the anaesthesia and intensive care workstation.

Local, Regional and Large Scale Integrated Networks

DTIC Science & Technology

1975-08-01

e.g., [Abramson, 1970, 1973, Kleinrock, 1973, Kleinrock, 1975, Roberts, 1973, Gitman , 19𔃿] , have shown that this "fixed assignment" of the...Abramson, 1973, ■- Kleinrock, 1973]), or intentionally avoid the issue of packet routing by proper assumptions [ Gitman , 1975]. The issue of...Communications Sys- tems," Memorandum RM-4781-PR, The Rand Corpora- tion, February 1966. Frank, H., I. Gitman , R. Van Slyke, "Pc-jket I.adio System

Intelligent control system based on ARM for lithography tool

NASA Astrophysics Data System (ADS)

Chen, Changlong; Tang, Xiaoping; Hu, Song; Wang, Nan

2014-08-01

The control system of traditional lithography tool is based on PC and MCU. The PC handles the complex algorithm, human-computer interaction, and communicates with MCU via serial port; The MCU controls motors and electromagnetic valves, etc. This mode has shortcomings like big volume, high power consumption, and wasting of PC resource. In this paper, an embedded intelligent control system of lithography tool, based on ARM, is provided. The control system used S5PV210 as processor, completing the functions of PC in traditional lithography tool, and provided a good human-computer interaction by using LCD and capacitive touch screen. Using Android4.0.3 as operating system, the equipment provided a cool and easy UI which made the control more user-friendly, and implemented remote control and debug, pushing video information of product by network programming. As a result, it's convenient for equipment vendor to provide technical support for users. Finally, compared with traditional lithography tool, this design reduced the PC part, making the hardware resources efficiently used and reducing the cost and volume. Introducing embedded OS and the concepts in "The Internet of things" into the design of lithography tool can be a development trend.

Multi-terminal remote monitoring and warning system using Micro Air Vehicle for dangerous environment

NASA Astrophysics Data System (ADS)

Yu, Yanan; Wang, Xiaoxun; He, Chengcheng; Lai, Chenlong; Liu, Yuanchao

2015-11-01

For overcoming the problems such as remote operation and dangerous tasks, multi-terminal remote monitoring and warning system based on STC89C52 Micro Control Unit and wireless communication technique was proposed. The system with MCU as its core adopted multiple sets of sensor device to monitor environment parameters of different locations, such as temperature, humidity, smoke other harmful gas concentration. Data information collected was transmitted remotely by wireless transceiver module, and then multi-channel data parameter was processed and displayed through serial communication protocol between the module and PC. The results of system could be checked in the form of web pages within a local network which plays a wireless monitoring and warning role. In a remote operation, four-rotor micro air vehicle which fixed airborne data acquisition device was utilized as a middleware between collecting terminal and PC to increase monitoring scope. Whole test system has characteristics of simple construction, convenience, real time ability and high reliability, which could meet the requirements of actual use.

Doctors' experience of coordination across care levels and associated factors. A cross-sectional study in public healthcare networks of six Latin American countries.

PubMed

Vázquez, María-Luisa; Vargas, Ingrid; Garcia-Subirats, Irene; Unger, Jean-Pierre; De Paepe, Pierre; Mogollón-Pérez, Amparo Susana; Samico, Isabella; Eguiguren, Pamela; Cisneros, Angelica-Ivonne; Huerta, Adriana; Muruaga, María-Cecilia; Bertolotto, Fernando

2017-06-01

Improving coordination between primary care (PC) and secondary care (SC) has become a policy priority in recent years for many Latin American public health systems looking to reinforce a healthcare model based on PC. However, despite being a longstanding concern, it has scarcely been analyzed in this region. This paper analyses the level of clinical coordination between PC and SC experienced by doctors and explores influencing factors in public healthcare networks of Argentina, Brazil, Chile, Colombia, Mexico and Uruguay. A cross-sectional study was carried out based on a survey of doctors working in the study networks (348 doctors per country). The COORDENA questionnaire was applied to measure their experiences of clinical management and information coordination, and their related factors. Descriptive analyses were conducted and a multivariate logistic regression model was generated to assess the relationship between general perception of care coordination and associated factors. With some differences between countries, doctors generally reported limited care coordination, mainly in the transfer of information and communication for the follow-up of patients and access to SC for referred patients, especially in the case of PC doctors and, to a lesser degree, inappropriate clinical referrals and disagreement over treatments, in the case of SC doctors. Factors associated with a better general perception of coordination were: being a SC doctor, considering that there is enough time for coordination within consultation hours, job and salary satisfaction, identifying the PC doctor as the coordinator of patient care across levels, knowing the doctors of the other care level and trusting in their clinical skills. These results provide evidence of problems in the implementation of a primary care-based model that require changes in aspects of employment, organization and interaction between doctors, all key factors for coordination. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

An evaluation of a palliative care outreach programme for children with Burkitt lymphoma in rural Cameroon.

PubMed

Tamannai, Mona; Kaah, Joel; Mbah, Glenn; Ndimba, Joseph; D'Souza, Catherine; Wharin, Paul; Hesseling, Peter B

2015-07-01

Palliative care (PC) is the most appropriate treatment for patients with life-limiting, incurable diseases, but it is a relatively new concept in sub-Saharan Africa (SSA). A lack of curative treatment options for some conditions creates a great need for PC, but such services are rarely provided in SSA. More research into PC in SSA is urgently needed to create an evidence base to confirm the importance of appropriate PC services. To gain a better understanding of the needs of patients and their families visited by a children's PC nurse in Cameroon and to identify aspects of the service that can be improved. A qualitative study design with semi-structured interviews was used. Tape-recorded interviews were transcribed and thematically analysed. Twelve interviews were conducted with patients, carers and nurses. Financial aid, general disease improvement and prayers were the directly expressed needs of service recipients. Specialist training in children's PC was the main need expressed by the nurses. Open communication about clinical status and treatment failure, more detailed counselling, more distraction for patients and respite for carers were identified as underlying needs. It is possible to provide an effective children's PC service that meets the most urgent needs of recipients in a rural setting in SSA. Recommendations include improved counselling, specialist education for staff, expansion of local support networks and more frequent home visits. More studies are needed to help define the need for PC in children with life-limiting diseases.

Turbo Pascal Implementation of a Distributed Processing Network of MS-DOS Microcomputers Connected in a Master-Slave Configuration

DTIC Science & Technology

1989-12-01

Interrupt Procedures ....... 29 13. Support for a Larger Memory Model ................ 29 C. IMPLEMENTATION ........................................ 29...describe the programmer’s model of the hardware utilized in the microcomputers and interrupt driven serial communication considerations. Chapter III...Central Processor Unit The programming model of Table 2.1 is common to the Intel 8088, 8086 and 80x86 series of microprocessors used in the IBM PC/AT

Implementation of RS-485 Communication between PLC and PC of Distributed Control System Based on VB

NASA Astrophysics Data System (ADS)

Lian Zhang, Chuan; Da Huang, Zhi; Qing Zhou, Gui; Chong, Kil To

2015-05-01

This paper focuses on achieving RS-485 communication between programmable logical controller (PLC) and PC based on visual basic 6.0 (VB6.0) on an experimental automatic production line. Mitsubishi FX2N PLCs and a PC are chosen as slave stations and main station, respectively. Monitoring software is developed using VB6.0 for data input/output, flow control and online parameters setting. As a result, all functions are fulfilled with robust performance. It is concluded from results that one PC can monitor several PLCs using RS-485 communication.

Robot welding process control

NASA Technical Reports Server (NTRS)

Romine, Peter L.

1991-01-01

This final report documents the development and installation of software and hardware for Robotic Welding Process Control. Primary emphasis is on serial communications between the CYRO 750 robotic welder, Heurikon minicomputer running Hunter & Ready VRTX, and an IBM PC/AT, for offline programming and control and closed-loop welding control. The requirements for completion of the implementation of the Rocketdyne weld tracking control are discussed. The procedure for downloading programs from the Intergraph, over the network, is discussed. Conclusions are made on the results of this task, and recommendations are made for efficient implementation of communications, weld process control development, and advanced process control procedures using the Heurikon.

Network connectivity enhancement by exploiting all optical multicast in semiconductor ring laser

NASA Astrophysics Data System (ADS)

Siraj, M.; Memon, M. I.; Shoaib, M.; Alshebeili, S.

2015-03-01

The use of smart phone and tablet applications will provide the troops for executing, controlling and analyzing sophisticated operations with the commanders providing crucial documents directly to troops wherever and whenever needed. Wireless mesh networks (WMNs) is a cutting edge networking technology which is capable of supporting Joint Tactical radio System (JTRS).WMNs are capable of providing the much needed bandwidth for applications like hand held radios and communication for airborne and ground vehicles. Routing management tasks can be efficiently handled through WMNs through a central command control center. As the spectrum space is congested, cognitive radios are a much welcome technology that will provide much needed bandwidth. They can self-configure themselves, can adapt themselves to the user requirement, provide dynamic spectrum access for minimizing interference and also deliver optimal power output. Sometimes in the indoor environment, there are poor signal issues and reduced coverage. In this paper, a solution utilizing (CR WMNs) over optical network is presented by creating nanocells (PCs) inside the indoor environment. The phenomenon of four-wave mixing (FWM) is exploited to generate all-optical multicast using semiconductor ring laser (SRL). As a result same signal is transmitted at different wavelengths. Every PC is assigned a unique wavelength. By using CR technology in conjunction with PC will not only solve network coverage issue but will provide a good bandwidth to the secondary users.

[Importance of an outpatient record in obstetric anesthesia].

PubMed

Lanza, V; Mercadante, S; Pignataro, A; Guglielmo, L; Villari, P; Di Fiore, G; Sapio, M; De Michele, P; Vegna, G

1991-01-01

A computerised record was used to collect data following an anesthesiological check-up of pregnant women at approximately 30 weeks of pregnancy. The record was input onto a portable PC in the anesthesia outpatient clinic, memorized on disk (3.5") and then transferred onto a PC network (one PC for each operating theatre) for "real time" consultation of each patient's data. All pregnant women attending the antenatal clinico were also given a folder illustrating epidural anesthetic techniques. Seven hundred and nine outpatient visits have been performed over the past two years with a 62% utilisation ratio. The collection of data using a computerised system allows a rapid and efficacious system of communication to be set up among the membranes of the anesthesiological team, thus encouraging the use of epidural techniques during labour. The distribution of the folder also facilitated the task of the anesthetist who found that pregnant women visiting the anesthesia clinic were already familiar with the epidural technique.

A survey of mobile phone use in the provision of palliative care services in the African region and priorities for future development.

PubMed

Allsop, Matthew J; Namisango, Eve; Powell, Richard A

2018-01-01

Introduction Palliative care (PC) services in the African region need to adapt to manage rising numbers of patients with cancer or other life-limiting conditions. Mobile phone use in healthcare delivery (mHealth) is at an early stage of development for PC, but may provide new approaches to supporting patients regionally, particularly those with non-communicable diseases. Methods We conducted an online survey of 51 PC providers across 21 countries in the African region to identify: (i) current mHealth use in PC service delivery; (ii) potential barriers to mHealth use; and (iii) provider priorities for research development. Results mHealth approaches were reported across 71.4% of services in which respondents were based. Barriers to mHealth research include patients not having access to phones, mobile network access, and limited access to expertise and hardware required for mHealth. Research priorities were identified which included exploring ways of incorporating mHealth into patient care and ensuring access and relevance of mHealth for patients and health professionals. Discussion mHealth approaches are present across PC services in the African region, but so too are barriers to their use. Further work is required to explore how existing mHealth activities might be further developed and aligned with priority areas for PC development. Crucially, user engagement that seeks to understand the preferences and priorities of patients with PC needs, their caregivers, and those involved in the provision of PC should remain central to these efforts.

In-Silico Integration Approach to Identify a Key miRNA Regulating a Gene Network in Aggressive Prostate Cancer

PubMed Central

Colaprico, Antonio; Bontempi, Gianluca; Castiglioni, Isabella

2018-01-01

Like other cancer diseases, prostate cancer (PC) is caused by the accumulation of genetic alterations in the cells that drives malignant growth. These alterations are revealed by gene profiling and copy number alteration (CNA) analysis. Moreover, recent evidence suggests that also microRNAs have an important role in PC development. Despite efforts to profile PC, the alterations (gene, CNA, and miRNA) and biological processes that correlate with disease development and progression remain partially elusive. Many gene signatures proposed as diagnostic or prognostic tools in cancer poorly overlap. The identification of co-expressed genes, that are functionally related, can identify a core network of genes associated with PC with a better reproducibility. By combining different approaches, including the integration of mRNA expression profiles, CNAs, and miRNA expression levels, we identified a gene signature of four genes overlapping with other published gene signatures and able to distinguish, in silico, high Gleason-scored PC from normal human tissue, which was further enriched to 19 genes by gene co-expression analysis. From the analysis of miRNAs possibly regulating this network, we found that hsa-miR-153 was highly connected to the genes in the network. Our results identify a four-gene signature with diagnostic and prognostic value in PC and suggest an interesting gene network that could play a key regulatory role in PC development and progression. Furthermore, hsa-miR-153, controlling this network, could be a potential biomarker for theranostics in high Gleason-scored PC. PMID:29562723

Evaluation of Physician and Nurse Dyad Training Procedures to Deliver a Palliative and End-of-Life Communication Intervention to Parents of Children with a Brain Tumor

PubMed Central

Hendricks-Ferguson, Verna L.; Kane, Javier R.; Pradhan, Kamnesh R.; Shih, Chie-Schin; Gauvain, Karen M.; Baker, Justin N.; Haase, Joan E.

2017-01-01

When a child’s prognosis is poor, physicians and nurses (MDs/RNs) often struggle with initiating discussions about palliative and end-of-life care (PC/EOL) early in the course of illness trajectory. We describe evaluation of training procedures used to prepare MD/RN dyads to deliver an intervention entitled: Communication Plan: Early Through End of Life (COMPLETE) intervention. Our training was delivered to 5 pediatric neuro-oncologists and 8 pediatric nurses by a team of expert consultants (i.e., in medical ethics, communication, and PC/EOL) and parent advisors. Although half of the group received training in a 1-day program and half in a 2-day program, content for all participants included 4 modules: family assessment, goal-directed treatment planning, anticipatory guidance, and staff communication and follow-up. Evaluations included dichotomous ratings and qualitative comments on content, reflection, and skills practice for each module. Positive aspects of our training included parent advisers’ insights, emphasis on hope and non-abandonment messages, written materials to facilitate PC/EOL communication, and an MD/RN dyad approach. Lessons learned and challenges related to our training procedures will be described. Overall, the MDs and RNs reported that our PC/EOL communication-training procedures were helpful and useful. Future investigators should carefully plan training procedures for PC/EOL communication interventions. PMID:25623029

Application of total distributed control system in car-body inspection

NASA Astrophysics Data System (ADS)

Yang, Xueyou; Ren, Dahai; Wang, Zhong; Ye, Shenghua; Lu, Hongbo; Duan, Jilin

1996-08-01

An application of distributed control system in Autocar-body Visual Inspection Station is presented in the paper, a distributed control system using PC as the host processor and single-chip microcomputer as the slave controller is proposed. In this paper, the physical interface of the control network and the relevant hardware are introduced. Meanwhile, a minute research on data communication is performed, relevant protocols on data framing, instruction codes and channel access methods have been laid down and part of related software is presented.

Integrating electronic patient records into a multi-media clinic-based simulation center using a PC blade platform: a foundation for a new pedagogy in dentistry.

PubMed

Taylor, David; Valenza, John A; Spence, James M; Baber, Randolph H

2007-10-11

Simulation has been used for many years in dental education, but the educational context is typically a laboratory divorced from the clinical setting, which impairs the transfer of learning. Here we report on a true simulation clinic with multimedia communication from a central teaching station. Each of the 43 fully-functioning student operatories includes a thin-client networked computer with access to an Electronic Patient Record (EPR).

Visual Communications And Image Processing

NASA Astrophysics Data System (ADS)

Hsing, T. Russell; Tzou, Kou-Hu

1989-07-01

This special issue on Visual Communications and Image Processing contains 14 papers that cover a wide spectrum in this fast growing area. For the past few decades, researchers and scientists have devoted their efforts to these fields. Through this long-lasting devotion, we witness today the growing popularity of low-bit-rate video as a convenient tool for visual communication. We also see the integration of high-quality video into broadband digital networks. Today, with more sophisticated processing, clearer and sharper pictures are being restored from blurring and noise. Also, thanks to the advances in digital image processing, even a PC-based system can be built to recognize highly complicated Chinese characters at the speed of 300 characters per minute. This special issue can be viewed as a milestone of visual communications and image processing on its journey to eternity. It presents some overviews on advanced topics as well as some new development in specific subjects.

Multimission Telemetry Visualization (MTV) system: A mission applications project from JPL's Multimedia Communications Laboratory

NASA Technical Reports Server (NTRS)

Koeberlein, Ernest, III; Pender, Shaw Exum

1994-01-01

This paper describes the Multimission Telemetry Visualization (MTV) data acquisition/distribution system. MTV was developed by JPL's Multimedia Communications Laboratory (MCL) and designed to process and display digital, real-time, science and engineering data from JPL's Mission Control Center. The MTV system can be accessed using UNIX workstations and PC's over common datacom and telecom networks from worldwide locations. It is designed to lower data distribution costs while increasing data analysis functionality by integrating low-cost, off-the-shelf desktop hardware and software. MTV is expected to significantly lower the cost of real-time data display, processing, distribution, and allow for greater spacecraft safety and mission data access.

77 FR 43592 - Public Utility District No. 1 of Snohomish County, WA; Notice of Technical Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-25

... issues raised by PC Landing and the Federal Communications Commission regarding the proximity of the proposed Admiralty Inlet Tidal Project to PC Landing's fiber optic communication cable, and discuss the...

Evaluation of Physician and Nurse Dyad Training Procedures to Deliver a Palliative and End-of-Life Communication Intervention to Parents of Children with a Brain Tumor.

PubMed

Hendricks-Ferguson, Verna L; Kane, Javier R; Pradhan, Kamnesh R; Shih, Chie-Schin; Gauvain, Karen M; Baker, Justin N; Haase, Joan E

2015-01-01

When a child's prognosis is poor, physicians and nurses (MDs/RNs) often struggle with initiating discussions about palliative and end-of-life care (PC/EOL) early in the course of illness trajectory. We describe evaluation of training procedures used to prepare MD/RN dyads to deliver an intervention entitled: Communication Plan: Early Through End of Life (COMPLETE) intervention. Our training was delivered to 5 pediatric neuro-oncologists and 8 pediatric nurses by a team of expert consultants (i.e., in medical ethics, communication, and PC/EOL) and parent advisors. Although half of the group received training in a 1-day program and half in a 2-day program, content for all participants included 4 modules: family assessment, goal-directed treatment planning, anticipatory guidance, and staff communication and follow-up. Evaluations included dichotomous ratings and qualitative comments on content, reflection, and skills practice for each module. Positive aspects of our training included parent advisers' insights, emphasis on hope and non-abandonment messages, written materials to facilitate PC/EOL communication, and an MD/RN dyad approach. Lessons learned and challenges related to our training procedures will be described. Overall, the MDs and RNs reported that our PC/EOL communication-training procedures were helpful and useful. Future investigators should carefully plan training procedures for PC/EOL communication interventions. © 2015 by Association of Pediatric Hematology/Oncology Nurses.

Maturation of Cerebellar Purkinje Cell Population Activity during Postnatal Refinement of Climbing Fiber Network.

PubMed

Good, Jean-Marc; Mahoney, Michael; Miyazaki, Taisuke; Tanaka, Kenji F; Sakimura, Kenji; Watanabe, Masahiko; Kitamura, Kazuo; Kano, Masanobu

2017-11-21

Neural circuits undergo massive refinements during postnatal development. In the developing cerebellum, the climbing fiber (CF) to Purkinje cell (PC) network is drastically reshaped by eliminating early-formed redundant CF to PC synapses. To investigate the impact of CF network refinement on PC population activity during postnatal development, we monitored spontaneous CF responses in neighboring PCs and the activity of populations of nearby CF terminals using in vivo two-photon calcium imaging. Population activity is highly synchronized in newborn mice, and the degree of synchrony gradually declines during the first postnatal week in PCs and, to a lesser extent, in CF terminals. Knockout mice lacking P/Q-type voltage-gated calcium channel or glutamate receptor δ2, in which CF network refinement is severely impaired, exhibit an abnormally high level of synchrony in PC population activity. These results suggest that CF network refinement is a structural basis for developmental desynchronization and maturation of PC population activity. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

Data communication between Panasonic PLC and PC using SerialPort control in C#.NET environment

NASA Astrophysics Data System (ADS)

Gao, Ting; Gan, Xiaochuan; Ma, Liqun

2015-02-01

With the gradual promotion of Microsoft.NET platform, C# as an object-oriented programming language based on the platform has been widely used. Therefore, more attention is concentrated on how to achieve the communication between Panasonic PLC and PC efficiently and fast in C#.NET environment. In this paper, a method of using SerialPort control which could be used for achieving communication between PLC and PC is introduced. Meanwhile, the reason of abnormal thread when displayed the receiving data in form is analyzed and the programming method to solve the problem of thread safety is designed. Achieving the communication of Panasonic PLC and PC in C#.NET environment can give full play to the advantages of the .NET framework. It is practical, easy communication, high reliability and can combine with other measurement and calibration procedures effectively and conveniently. Configuration software is expensive and can only communicate with PLC separately, but these shortcomings can be solved in C#.NET environment. A well-designed user interface realized real-time monitoring of PLC parameters and achieved management and control integration. The experiment show that this method of data transfer is accurate and the program' running is stable.

Phase transition in NK-Kauffman networks and its correction for Boolean irreducibility

NASA Astrophysics Data System (ADS)

Zertuche, Federico

2014-05-01

In a series of articles published in 1986, Derrida and his colleagues studied two mean field treatments (the quenched and the annealed) for NK-Kauffman networks. Their main results lead to a phase transition curve Kc 2 pc(1-pc)=1 (0

Development of the New DAQ System for the SD Array of TA×4 and TALE

NASA Astrophysics Data System (ADS)

Takahashi, Yuichi; Sahara, Ryosuke; Konishi, Shogo; Goto, Takashi; Ogio, Shoichi

The data acquisition (DAQ) system for the surface detector (SD) arrays of TA×4 and TALE will be presented. Each SD records digital signals with 50 MHz FADCs and sends the data to a central communication center (of the "communication tower") via a wireless network system. The technique employed here is based on the currently-running DAQ system of the Telescope Array, and there are some improvements including i) replacement of a wireless LAN module with a custom protocol to another with TCP/IP, and ii) replacement of the "tower electronics" to a generic Linux board PC of Raspberry Pi Type II B. The details and performance of the new DAQ system are described below.

A TinyOS-enabled MICA2-based wireless neural interface.

PubMed

Farshchi, Shahin; Nuyujukian, Paul H; Pesterev, Aleksey; Mody, Istvan; Judy, Jack W

2006-07-01

Existing approaches used to develop compact low-power multichannel wireless neural recording systems range from creating custom-integrated circuits to assembling commercial-off-the-shelf (COTS) PC-based components. Custom-integrated-circuit designs yield extremely compact and low-power devices at the expense of high development and upgrade costs and turn-around times, while assembling COTS-PC-technology yields high performance at the expense of large system size and increased power consumption. To achieve a balance between implementing an ultra-compact custom-fabricated neural transceiver and assembling COTS-PC-technology, an overlay of a neural interface upon the TinyOS-based MICA2 platform is described. The system amplifies, digitally encodes, and transmits neural signals real-time at a rate of 9.6 kbps, while consuming less than 66 mW of power. The neural signals are received and forwarded to a client PC over a serial connection. This data rate can be divided for recording on up to 6 channels, with a resolution of 8 bits/sample. This work demonstrates the strengths and limitations of the TinyOS-based sensor technology as a foundation for chronic remote biological monitoring applications and, thus, provides an opportunity to create a system that can leverage from the frequent networking and communications advancements being made by the global TinyOS-development community.

A DNA sequence analysis package for the IBM personal computer.

PubMed Central

Lagrimini, L M; Brentano, S T; Donelson, J E

1984-01-01

We present here a collection of DNA sequence analysis programs, called "PC Sequence" (PCS), which are designed to run on the IBM Personal Computer (PC). These programs are written in IBM PC compiled BASIC and take full advantage of the IBM PC's speed, error handling, and graphics capabilities. For a modest initial expense in hardware any laboratory can use these programs to quickly perform computer analysis on DNA sequences. They are written with the novice user in mind and require very little training or previous experience with computers. Also provided are a text editing program for creating and modifying DNA sequence files and a communications program which enables the PC to communicate with and collect information from mainframe computers and DNA sequence databases. PMID:6546433

Network and user interface for PAT DOME virtual motion environment system

NASA Technical Reports Server (NTRS)

Worthington, J. W.; Duncan, K. M.; Crosier, W. G.

1993-01-01

The Device for Orientation and Motion Environments Preflight Adaptation Trainer (DOME PAT) provides astronauts a virtual microgravity sensory environment designed to help alleviate tye symptoms of space motion sickness (SMS). The system consists of four microcomputers networked to provide real time control, and an image generator (IG) driving a wide angle video display inside a dome structure. The spherical display demands distortion correction. The system is currently being modified with a new graphical user interface (GUI) and a new Silicon Graphics IG. This paper will concentrate on the new GUI and the networking scheme. The new GUI eliminates proprietary graphics hardware and software, and instead makes use of standard and low cost PC video (CGA) and off the shelf software (Microsoft's Quick C). Mouse selection for user input is supported. The new Silicon Graphics IG requires an Ethernet interface. The microcomputer known as the Real Time Controller (RTC), which has overall control of the system and is written in Ada, was modified to use the free public domain NCSA Telnet software for Ethernet communications with the Silicon Graphics IG. The RTC also maintains the original ARCNET communications through Novell Netware IPX with the rest of the system. The Telnet TCP/IP protocol was first used for real-time communication, but because of buffering problems the Telnet datagram (UDP) protocol needed to be implemented. Since the Telnet modules are written in C, the Adap pragma 'Interface' was used to interface with the network calls.

Artificial Potential Field Controllers for Robust Communications in a Network of Swarm Robots

DTIC Science & Technology

2005-05-18

vectors are less than 90◦ apart. Algorithm 1 The Algorithm for generating a feasible set of vectors P ← set of high priority vectors Csum ← [( LOS1 +R1...the 46 C program was finished reading and writing the values to the serial line it would delete the timing file. Only after the timing file had been... deleted would the base station write new values for the wheel velocities. The timing file kept both the Linux PC and the base station synchronized so

Enhancing PC Cluster-Based Parallel Branch-and-Bound Algorithms for the Graph Coloring Problem

NASA Astrophysics Data System (ADS)

Taoka, Satoshi; Takafuji, Daisuke; Watanabe, Toshimasa

A branch-and-bound algorithm (BB for short) is the most general technique to deal with various combinatorial optimization problems. Even if it is used, computation time is likely to increase exponentially. So we consider its parallelization to reduce it. It has been reported that the computation time of a parallel BB heavily depends upon node-variable selection strategies. And, in case of a parallel BB, it is also necessary to prevent increase in communication time. So, it is important to pay attention to how many and what kind of nodes are to be transferred (called sending-node selection strategy). In this paper, for the graph coloring problem, we propose some sending-node selection strategies for a parallel BB algorithm by adopting MPI for parallelization and experimentally evaluate how these strategies affect computation time of a parallel BB on a PC cluster network.

A Connection Model between the Positioning Mechanism and Ultrasonic Measurement System via a Web Browser to Assess Acoustic Target Strength

NASA Astrophysics Data System (ADS)

Ishii, Ken; Imaizumi, Tomohito; Abe, Koki; Takao, Yoshimi; Tamura, Shuko

This paper details a network-controlled measurement system for use in fisheries engineering. The target strength (TS) of fish is important in order to convert acoustic integration values obtained during acoustic surveys into estimates of fish abundance. The target strength pattern is measured with the combination of the rotation system for the aspect of the sample and the echo data acquisition system using the underwater supersonic wave. The user interface of the network architecture is designed for collaborative use with researchers in other organizations. The flexible network architecture is based on the web direct-access model for the rotation mechanism. The user interface is available for monitoring and controlling via a web browser that is installed in any terminal PC (personal computer). Previously the combination of two applications was performed not by a web browser but by the exclusive interface program. So a connection model is proposed between two applications by indirect communication via the DCOM (Distributed Component Object Model) server and added in the web direct-access model. A prompt report system in the TS measurement system and a positioning and measurement system using an electric flatcar via a web browser are developed. By a secure network architecture, DCOM communications via both Intranet and LAN are successfully certificated.

Design of a Channel Error Simulator using Virtual Instrument Techniques for the Initial Testing of TCP/IP and SCPS Protocols

NASA Technical Reports Server (NTRS)

Horan, Stephen; Wang, Ru-Hai

1999-01-01

There exists a need for designers and developers to have a method to conveniently test a variety of communications parameters for an overall system design. This is no different when testing network protocols as when testing modulation formats. In this report, we discuss a means of providing a networking test device specifically designed to be used for space communications. This test device is a PC-based Virtual Instrument (VI) programmed using the LabVIEW(TM) version 5 software suite developed by National Instruments(TM)TM. This instrument was designed to be portable and usable by others without special, additional equipment. The programming was designed to replicate a VME-based hardware module developed earlier at New Mexico State University (NMSU) and to provide expanded capabilities exceeding the baseline configuration existing in that module. This report describes the design goals for the VI module in the next section and follows that with a description of the design of the VI instrument. This is followed with a description of the validation tests run on the VI. An application of the error-generating VI to networking protocols is then given.

[Making a low cost IPSec router on Linux and the assessment for practical use].

PubMed

Amiki, M; Horio, M

2001-09-01

We installed Linux and FreeS/WAN on a PC/AT compatible machine to make an IPSec router. We measured the time of ping/ftp, only in the university, between the university and the external network. Between the university and the external network (the Internet), there were no differences. Therefore, we concluded that CPU load was not remarkable at low speed networks, because packets exchanged via the Internet are small, or compressions of VPN are more effective than encoding and decoding. On the other hand, in the university, the IPSec router performed down about 20-30% compared with normal IP communication, but this is not a serious problem for practical use. Recently, VPN machines are becoming cheaper, but they do not function sufficiently to create a fundamental VPN environment. Therefore, if one wants a fundamental VPN environment at a low cost, we believe you should select a VPN router on Linux.

Training Pediatric Fellows in Palliative Care: A Pilot Comparison of Simulation Training and Didactic Education.

PubMed

Brock, Katharine E; Cohen, Harvey J; Sourkes, Barbara M; Good, Julie J; Halamek, Louis P

2017-10-01

Pediatric fellows receive little palliative care (PC) education and have few opportunities to practice communication skills. In this pilot study, we assessed (1) the relative effectiveness of simulation-based versus didactic education, (2) communication skill retention, and (3) effect on PC consultation rates. Thirty-five pediatric fellows in cardiology, critical care, hematology/oncology, and neonatology at two institutions enrolled: 17 in the intervention (simulation-based) group (single institution) and 18 in the control (didactic education) group (second institution). Intervention group participants participated in a two-day program over three months (three simulations and videotaped PC panel). Control group participants received written education designed to be similar in content and time. (1) Self-assessment questionnaires were completed at baseline, post-intervention and three months; mean between-group differences for each outcome measure were assessed. (2) External reviewers rated simulation-group encounters on nine communication domains. Within-group changes over time were assessed. (3) The simulation-based site's PC consultations were compared in the six months pre- and post-intervention. Compared to the control group, participants in the intervention group improved in self-efficacy (p = 0.003) and perceived adequacy of medical education (p < 0.001), but not knowledge (p = 0.20). Reviewers noted nonsustained improvement in four domains: relationship building (p = 0.01), opening discussion (p = 0.03), gathering information (p = 0.01), and communicating accurate information (p = 0.04). PC consultation rate increased 64%, an improvement when normalized to average daily census (p = 0.04). This simulation-based curriculum is an effective method for improving PC comfort, education, and consults. More frequent practice is likely needed to lead to sustained improvements in communication competence.

Optimal topology to minimizing congestion in connected communication complex network

NASA Astrophysics Data System (ADS)

Benyoussef, M.; Ez-Zahraouy, H.; Benyoussef, A.

In this paper, a new model of the interdependent complex network is proposed, based on two assumptions that (i) the capacity of a node depends on its degree, and (ii) the traffic load depends on the distribution of the links in the network. Based on these assumptions, the presented model proposes a method of connection not based on the node having a higher degree but on the region containing hubs. It is found that the final network exhibits two kinds of degree distribution behavior, depending on the kind and the way of the connection. This study reveals a direct relation between network structure and traffic flow. It is found that pc the point of transition between the free flow and the congested phase depends on the network structure and the degree distribution. Moreover, this new model provides an improvement in the traffic compared to the results found in a single network. The same behavior of degree distribution found in a BA network and observed in the real world is obtained; except for this model, the transition point between the free phase and congested phase is much higher than the one observed in a network of BA, for both static and dynamic protocols.

Research on realization scheme of interactive voice response (IVR) system

NASA Astrophysics Data System (ADS)

Jin, Xin; Zhu, Guangxi

2003-12-01

In this paper, a novel interactive voice response (IVR) system is proposed, which is apparently different from the traditional. Using software operation and network control, the IVR system is presented which only depends on software in the server in which the system lies and the hardware in network terminals on user side, such as gateway (GW), personal gateway (PG), PC and so on. The system transmits the audio using real time protocol (RTP) protocol via internet to the network terminals and controls flow using finite state machine (FSM) stimulated by H.245 massages sent from user side and the system control factors. Being compared with other existing schemes, this IVR system results in several advantages, such as greatly saving the system cost, fully utilizing the existing network resources and enhancing the flexibility. The system is capable to be put in any service server anywhere in the Internet and even fits for the wireless applications based on packet switched communication. The IVR system has been put into reality and passed the system test.

Wireless home monitoring and health care activity management through the Internet in patients with chronic diseases.

PubMed

Tura, Andrea; Quareni, Luca; Longo, David; Condoluci, Claudia; van Rijn, Astrid; Albertini, Giorgio

2005-12-01

A project was developed for the creation of an Internet-based network aimed at improved management of home care activities in brain-injured children. At the patient's side, a home care unit was provided, made of a portable medical device, and a tablet PC. Measured clinical data were blood oxygen saturation, heart rate, breath rate and quantity of movement. Thanks to device portability, the patient was free to move while measurements were taken. At prescribed time intervals, measured data were automatically transmitted to the tablet PC via Bluetooth. From the tablet PC, data were transmitted remotely to a Service Centre (via ADSL or GPRS) and made available for consultation by health care professionals through the project Web portal. At the portal, other functionalities were also available, both for patients and families, and for professionals (such as weekly planning agenda, access to relevant information resources, communication tools). Information was delivered for the right participant through a workflow engine. A first trial involving nine patients was performed for two months. At the end, although some improvements were suggested, good acceptance was detected, and 78% of patients and families claimed to be interested in further use of the platform.

Development of dielectrophoresis MEMS device for PC12 cell patterning to elucidate nerve-network generation

NASA Astrophysics Data System (ADS)

Nakamachi, Eiji; Koga, Hirotaka; Morita, Yusuke; Yamamoto, Koji; Sakamoto, Hidetoshi

2018-01-01

We developed a PC12 cell trapping and patterning device by combining the dielectrophoresis (DEP) methodology and the micro electro mechanical systems (MEMS) technology for time-lapse observation of morphological change of nerve network to elucidate the generation mechanism of neural network. We succeeded a neural network generation, which consisted of cell body, axon and dendrites by using tetragonal and hexagonal cell patterning. Further, the time laps observations was carried out to evaluate the axonal extension rate. The axon extended in the channel and reached to the target cell body. We found that the shorter the PC12 cell distance, the less the axonal connection time in both tetragonal and hexagonal structures. After 48 hours culture, a maximum success rate of network formation was 85% in the case of 40 μm distance tetragonal structure.

Global and system-specific resting-state fMRI fluctuations are uncorrelated: principal component analysis reveals anti-correlated networks.

PubMed

Carbonell, Felix; Bellec, Pierre; Shmuel, Amir

2011-01-01

The influence of the global average signal (GAS) on functional-magnetic resonance imaging (fMRI)-based resting-state functional connectivity is a matter of ongoing debate. The global average fluctuations increase the correlation between functional systems beyond the correlation that reflects their specific functional connectivity. Hence, removal of the GAS is a common practice for facilitating the observation of network-specific functional connectivity. This strategy relies on the implicit assumption of a linear-additive model according to which global fluctuations, irrespective of their origin, and network-specific fluctuations are super-positioned. However, removal of the GAS introduces spurious negative correlations between functional systems, bringing into question the validity of previous findings of negative correlations between fluctuations in the default-mode and the task-positive networks. Here we present an alternative method for estimating global fluctuations, immune to the complications associated with the GAS. Principal components analysis was applied to resting-state fMRI time-series. A global-signal effect estimator was defined as the principal component (PC) that correlated best with the GAS. The mean correlation coefficient between our proposed PC-based global effect estimator and the GAS was 0.97±0.05, demonstrating that our estimator successfully approximated the GAS. In 66 out of 68 runs, the PC that showed the highest correlation with the GAS was the first PC. Since PCs are orthogonal, our method provides an estimator of the global fluctuations, which is uncorrelated to the remaining, network-specific fluctuations. Moreover, unlike the regression of the GAS, the regression of the PC-based global effect estimator does not introduce spurious anti-correlations beyond the decrease in seed-based correlation values allowed by the assumed additive model. After regressing this PC-based estimator out of the original time-series, we observed robust anti-correlations between resting-state fluctuations in the default-mode and the task-positive networks. We conclude that resting-state global fluctuations and network-specific fluctuations are uncorrelated, supporting a Resting-State Linear-Additive Model. In addition, we conclude that the network-specific resting-state fluctuations of the default-mode and task-positive networks show artifact-free anti-correlations.

Application of Aquaculture Monitoring System Based on CC2530

NASA Astrophysics Data System (ADS)

Chen, H. L.; Liu, X. Q.

In order to improve the intelligent level of aquaculture technology, this paper puts forward a remote wireless monitoring system based on ZigBee technology, GPRS technology and Android mobile phone platform. The system is composed of wireless sensor network (WSN), GPRS module, PC server, and Android client. The WSN was set up by CC2530 chips based on ZigBee protocol, to realize the collection of water quality parameters such as the water level, temperature, PH and dissolved oxygen. The GPRS module realizes remote communication between WSN and PC server. Android client communicates with server to monitor the level of water quality. The PID (proportion, integration, differentiation) control is adopted in the control part, the control commands from the android mobile phone is sent to the server, the server again send it to the lower machine to control the water level regulating valve and increasing oxygen pump. After practical testing to the system in Liyang, Jiangsu province, China, temperature measurement accuracy reaches 0.5°C, PH measurement accuracy reaches 0.3, water level control precision can be controlled within ± 3cm, dissolved oxygen control precision can be controlled within ±0.3 mg/L, all the indexes can meet the requirements, this system is very suitable for aquaculture.

Retromer associates with the cytoplasmic amino-terminus of polycystin-2.

PubMed

Tilley, Frances C; Gallon, Matthew; Luo, Chong; Danson, Chris M; Zhou, Jing; Cullen, Peter J

2018-05-03

Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic human disease, with around 12.5 million people affected worldwide. ADPKD results from mutations in either PKD1 or PKD2 , which encode the atypical G-protein coupled receptor polycystin-1 (PC1) and the transient receptor potential channel polycystin-2 (PC2) respectively. Although altered intracellular trafficking of PC1 and PC2 appear as an underlying feature of ADPKD, the mechanisms which govern vesicular transport of the polycystins through the biosynthetic and endosomal membrane networks remain to be fully elucidated. Here, we describe an interaction between PC2 and retromer, a master controller for the sorting of integral membrane proteins through the endo-lysosomal network. We show that association of PC2 with retromer occurs via a region in the PC2 cytoplasmic amino-terminal domain, independently of the retromer-binding Wiskott-Aldrich syndrome and scar homologue (WASH) complex. Based on observations that retromer preferentially interacts with a trafficking population of PC2, and that ciliary levels of PC1 are reduced upon mutation of key residues required for retromer-association in PC2, our data is consistent with the identification of PC2 as a retromer cargo protein. © 2018. Published by The Company of Biologists Ltd.

Possibility of a ferromagnetic and conducting metal-organic network

NASA Astrophysics Data System (ADS)

Mabrouk, Manel; Hayn, Roland; Denawi, Hassan; Ben Chaabane, Rafik

2018-05-01

In this paper, we present first principles calculations based on the spin-polarized generalized gradient approximation with on-site Coulomb repulsion term (SGGA + U), to explore the electronic and magnetic properties of the novel planar metal-organic networks TM-Pc and TM-TCNB (where TM means a transition metal of the 3d series: Ti, V, Cr, …, or Zn, Pc - Phthalocyanine, and TCNB - Tetracyanobenzene) as free-standing sheets. This work is an extension of two earlier research works dealing with the Mn (Mabrouk et al., 2015) and Fe (Mabrouk et al., 2017) cases. Our theoretical investigations demonstrate that TM-Pc are more stable than TM-TCNB. Our results unveil that all the TM-Pc frameworks have an insulating behavior with the exception of Mn-Pc which is half-metallic and favor antiferromagnetic order in the case of our magnetic systems except for V-Pc which is ferromagnetic. In contrast, the TM-TCNB networks are metallic at least in one spin direction and exhibit long-range ferromagnetic coupling in case for magnetic structures, which represent ideal candidates and an interesting prospect of unprecedented applications in spintronics. In addition, these results may shed light to achieve a new pathway on further experimental research in molecular spintronics.

New materials for old problems: What can nanomaterials do for biology and neuroscience?

NASA Astrophysics Data System (ADS)

Srivatsan, Malathi; Badanavalu, Mahadevappa P.; Yancey, Justin; Xie, Jining; Chen, Linfeng; Hankins, Philip T.; Yoon, Hargsoon; Varadan, Vijay K.

2009-03-01

The emerging field of nanotechnology offers the development of new materials and methods for crucial neuroscience applications namely (a) promoting survival and growth of the neurons, and (b) monitoring physiological signals generated in the nervous system such as excitation, synaptic transmission, release of neurotransmitter molecules and cell-to-cell communication. Such bio-devices will have several novel applications in basic science, laboratory analysis and therapeutic treatments. Our goals in this field of research include (a) development of new biocompatible substrates to guide and promote neuronal growth along specific pathways; (b) designing a neuron-friendly, bio-molecule delivery system for neuroprotection; (c) monitoring of electrical activity from neuron and also from neuronal networks; (d) determining the diffusion and intracellular localization of nanomaterial interacting with neurons at high resolution; and (e) detection of release of neurotransmitter molecules by means of newly designed nanosensors. Here we describe the fabrication and use of magnetic nanotubes and nanowire electrode arrays in studies using a cell culture model of neuronally differentiating rat pheochromocytoma (PC 12) cells. The magnetic nanotubes were fabricated by a template method yielding hematite (α-Fe2O3) nanotubes. These nanotubes were coupled with nerve growth factor (NGF). Vertically aligned nanowires were fabricated on glass substrates using the lithography-assisted template bonding (LATB) method. Rat pheochromocytoma (PC12) cells were cultured on these nanotubes and polylysine coated nanowire electrodes. Our results showed that magnetic nanotube bound NGF was available to PC12 cells as they showed significant differentiation into neurons. PC12 cells growing on nanowires in the presence of NGF differentiated into neurons capable of synthesis and release of dopamine upon stimulation. The neurons grew healthy neurites appearing to form synapses with other neurons in the dish. These results show that the magnetic nanotubes were capable of delivering neurotrophic molecules and the nanowire electrodes are neuron-friendly, promote cell to cell communication and can be used as bio-sensors in the nervous system.

An FPGA-Based Silicon Neuronal Network with Selectable Excitability Silicon Neurons

PubMed Central

Li, Jing; Katori, Yuichi; Kohno, Takashi

2012-01-01

This paper presents a digital silicon neuronal network which simulates the nerve system in creatures and has the ability to execute intelligent tasks, such as associative memory. Two essential elements, the mathematical-structure-based digital spiking silicon neuron (DSSN) and the transmitter release based silicon synapse, allow us to tune the excitability of silicon neurons and are computationally efficient for hardware implementation. We adopt mixed pipeline and parallel structure and shift operations to design a sufficient large and complex network without excessive hardware resource cost. The network with 256 full-connected neurons is built on a Digilent Atlys board equipped with a Xilinx Spartan-6 LX45 FPGA. Besides, a memory control block and USB control block are designed to accomplish the task of data communication between the network and the host PC. This paper also describes the mechanism of associative memory performed in the silicon neuronal network. The network is capable of retrieving stored patterns if the inputs contain enough information of them. The retrieving probability increases with the similarity between the input and the stored pattern increasing. Synchronization of neurons is observed when the successful stored pattern retrieval occurs. PMID:23269911

PC Tutor. Bericht uber ein PC-gestutzes Tutorensystem = PC Tutor. Report on a Tutoring System with Personal Computer. ZIFF Papiere 75.

ERIC Educational Resources Information Center

Fritsch, Helmut

A project was conducted to increase as well as to professionalize communication between tutors and learners in a West German university's distance education program by the use of personal computers. Two tutors worked on the systematic development of a PC-based correcting system. The goal, apart from developing general language skills in English,…

Computer (PC/Network) Coordinator.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. Center on Education and Training for Employment.

This publication contains 22 subjects appropriate for use in a competency list for the occupation of computer (PC/network) coordinator, 1 of 12 occupations within the business/computer technologies cluster. Each unit consists of a number of competencies; a list of competency builders is provided for each competency. Titles of the 22 units are as…

IBM PC/IX operating system evaluation plan

NASA Technical Reports Server (NTRS)

Dominick, Wayne D. (Editor); Granier, Martin; Hall, Philip P.; Triantafyllopoulos, Spiros

1984-01-01

An evaluation plan for the IBM PC/IX Operating System designed for IBM PC/XT computers is discussed. The evaluation plan covers the areas of performance measurement and evaluation, software facilities available, man-machine interface considerations, networking, and the suitability of PC/IX as a development environment within the University of Southwestern Louisiana NASA PC Research and Development project. In order to compare and evaluate the PC/IX system, comparisons with other available UNIX-based systems are also included.

Automobile inspection system based on wireless communication

NASA Astrophysics Data System (ADS)

Miao, Changyun; Ye, Chunqing

2010-07-01

This paper aims to research the Automobile Inspection System based on Wireless Communication, and suggests an overall design scheme which uses GPS for speed detection and Bluetooth and GPRS for communication. The communication between PDA and PC was realized by means of GPRS and TCP/IP; and the hardware circuit and software for detection terminal were devised by means of JINOU-3264 Bluetooth Module after analyzing the Bluetooth and its communication protocol. According to the results of debugging test, this system accomplished GPRS based data communication and management as well as the real-time detection on auto safety performance parameters in crash test via PC, whereby the need for mobility and reliability was met and the efficiency and level of detection was improved.

Prostate cancer cells specifically reorganize epithelial cell-fibroblast communication through proteoglycan and junction pathways.

PubMed

Suhovskih, Anastasia V; Kashuba, Vladimir I; Klein, George; Grigorieva, Elvira V

2017-01-02

Microenvironment and stromal fibroblasts are able to inhibit tumor cell proliferation both through secreted signaling molecules and direct cell-cell interactions but molecular mechanisms of these effects remain unclear. In this study, we investigated a role of cell-cell contact-related molecules (protein ECM components, proteoglycans (PGs) and junction-related molecules) in intercellular communications between the human TERT immortalized fibroblasts (BjTERT fibroblasts) and normal (PNT2) or cancer (LNCaP, PC3, DU145) prostate epithelial cells. It was shown that BjTERT-PNT2 cell coculture resulted in significant decrease of both BjTERT and PNT2 proliferation rates and reorganization of transcriptional activity of cell-cell contact-related genes in both cell types. Immunocytochemical staining revealed redistribution of DCN and LUM in PNT2 cells and significant increase of SDC1 at the intercellular contact zones between BjTERT and PNT2 cells, suggesting active involvement of the PGs in cell-cell contacts and contact inhibition of cell proliferation. Unlike to PNT2 cells, PC3 cells did not respond to BjTERT in terms of PGs expression, moderately increased transcriptional activity of junctions-related genes (especially tight junction) and failed to establish PC3-BjTERT contacts. At the same time, PC3 cells significantly down-regulated junctions-related genes (especially focal adhesions and adherens junctions) in BjTERT fibroblasts resulting in visible preference for homotypic PC3-PC3 over heterotypic PC3-BjTERT contacts and autonomous growth of PC3 clones. Taken together, the results demonstrate that an instructing role of fibroblasts to normal prostate epithelial cells is revoked by cancer cells through deregulation of proteoglycans and junction molecules expression and overall disorganization of fibroblast-cancer cell communication.

Speckle interferometry. Data acquisition and control for the SPID instrument.

NASA Astrophysics Data System (ADS)

Altarac, S.; Tallon, M.; Thiebaut, E.; Foy, R.

1998-08-01

SPID (SPeckle Imaging by Deconvolution) is a new speckle camera currently under construction at CRAL-Observatoire de Lyon. Its high spectral resolution and high image restoration capabilities open new astrophysical programs. The instrument SPID is composed of four main optical modules which are fully automated and computer controlled by a software written in Tcl/Tk/Tix and C. This software provides an intelligent assistance to the user by choosing observational parameters as a function of atmospheric parameters, computed in real time, and the desired restored image quality. Data acquisition is made by a photon-counting detector (CP40). A VME-based computer under OS9 controls the detector and stocks the data. The intelligent system runs under Linux on a PC. A slave PC under DOS commands the motors. These 3 computers communicate through an Ethernet network. SPID can be considered as a precursor for VLT's (Very Large Telescope, four 8-meter telescopes currently built in Chile by European Southern Observatory) very high spatial resolution camera.

Ionic network analysis of tectosilicates: the example of coesite at variable pressure.

PubMed

Reifenberg, Melina; Thomas, Noel W

2018-04-01

The method of ionic network analysis [Thomas (2017). Acta Cryst. B73, 74-86] is extended to tectosilicates through the example of coesite, the high-pressure polymorph of SiO 2 . The structural refinements of Černok et al. [Z. Kristallogr. (2014), 229, 761-773] are taken as the starting point for applying the method. Its purpose is to predict the unit-cell parameters and atomic coordinates at (p-T-X) values in-between those of diffraction experiments. The essential development step for tectosilicates is to define a pseudocubic parameterization of the O 4 cages of the SiO 4 tetrahedra. The six parameters a PC , b PC , c PC , α PC , β PC and γ PC allow a full quantification of the tetrahedral structure, i.e. distortion and enclosed volume. Structural predictions for coesite require that two separate quasi-planar networks are defined, one for the silicon ions and the other for the O 4 cage midpoints. A set of parametric curves is used to describe the evolution with pressure of these networks and the pseudocubic parameters. These are derived by fitting to the crystallographic data. Application of the method to monoclinic feldspars and to quartz and cristobalite is discussed. Further, a novel two-parameter quantification of the degree of tetrahedral distortion is described. At pressures in excess of ca 20.45 GPa it is not possible to find a self-consistent solution to the parametric curves for coesite, pointing to the likelihood of a phase transition.

Remodeling Pearson's Correlation for Functional Brain Network Estimation and Autism Spectrum Disorder Identification.

PubMed

Li, Weikai; Wang, Zhengxia; Zhang, Limei; Qiao, Lishan; Shen, Dinggang

2017-01-01

Functional brain network (FBN) has been becoming an increasingly important way to model the statistical dependence among neural time courses of brain, and provides effective imaging biomarkers for diagnosis of some neurological or psychological disorders. Currently, Pearson's Correlation (PC) is the simplest and most widely-used method in constructing FBNs. Despite its advantages in statistical meaning and calculated performance, the PC tends to result in a FBN with dense connections. Therefore, in practice, the PC-based FBN needs to be sparsified by removing weak (potential noisy) connections. However, such a scheme depends on a hard-threshold without enough flexibility. Different from this traditional strategy, in this paper, we propose a new approach for estimating FBNs by remodeling PC as an optimization problem, which provides a way to incorporate biological/physical priors into the FBNs. In particular, we introduce an L 1 -norm regularizer into the optimization model for obtaining a sparse solution. Compared with the hard-threshold scheme, the proposed framework gives an elegant mathematical formulation for sparsifying PC-based networks. More importantly, it provides a platform to encode other biological/physical priors into the PC-based FBNs. To further illustrate the flexibility of the proposed method, we extend the model to a weighted counterpart for learning both sparse and scale-free networks, and then conduct experiments to identify autism spectrum disorders (ASD) from normal controls (NC) based on the constructed FBNs. Consequently, we achieved an 81.52% classification accuracy which outperforms the baseline and state-of-the-art methods.

Real-time software-based end-to-end wireless visual communications simulation platform

NASA Astrophysics Data System (ADS)

Chen, Ting-Chung; Chang, Li-Fung; Wong, Andria H.; Sun, Ming-Ting; Hsing, T. Russell

1995-04-01

Wireless channel impairments pose many challenges to real-time visual communications. In this paper, we describe a real-time software based wireless visual communications simulation platform which can be used for performance evaluation in real-time. This simulation platform consists of two personal computers serving as hosts. Major components of each PC host include a real-time programmable video code, a wireless channel simulator, and a network interface for data transport between the two hosts. The three major components are interfaced in real-time to show the interaction of various wireless channels and video coding algorithms. The programmable features in the above components allow users to do performance evaluation of user-controlled wireless channel effects without physically carrying out these experiments which are limited in scope, time-consuming, and costly. Using this simulation platform as a testbed, we have experimented with several wireless channel effects including Rayleigh fading, antenna diversity, channel filtering, symbol timing, modulation, and packet loss.

Examination of time-reversal acoustics in shallow water and applications to noncoherent underwater communications.

PubMed

Smith, Kevin B; Abrantes, Antonio A M; Larraza, Andres

2003-06-01

The shallow water acoustic communication channel is characterized by strong signal degradation caused by multipath propagation and high spatial and temporal variability of the channel conditions. At the receiver, multipath propagation causes intersymbol interference and is considered the most important of the channel distortions. This paper examines the application of time-reversal acoustic (TRA) arrays, i.e., phase-conjugated arrays (PCAs), that generate a spatio-temporal focus of acoustic energy at the receiver location, eliminating distortions introduced by channel propagation. This technique is self-adaptive and automatically compensates for environmental effects and array imperfections without the need to explicitly characterize the environment. An attempt is made to characterize the influences of a PCA design on its focusing properties with particular attention given to applications in noncoherent underwater acoustic communication systems. Due to the PCA spatial diversity focusing properties, PC arrays may have an important role in an acoustic local area network. Each array is able to simultaneously transmit different messages that will focus only at the destination receiver node.

Understanding the spreading patterns of mobile phone viruses

NASA Astrophysics Data System (ADS)

Wang, Pu; Gonzalez, Marta; Hidalgo, Cesar; Barabasi, Albert-Laszlo

2009-03-01

Mobile viruses are little more than a nuisance today, but given our increased reliance on wireless communication, in the near future they could pose more risk than their PC based counterparts. Despite of the more than three hundred mobile viruses known so far, little is known about their spreading pattern, partly due to a lack of data on the communication and travel patterns of mobile phone users. Starting from the traffic and the communication pattern of six million mobile phone users, we model the vulnerability of mobile communications against potential virus outbreaks. We show that viruses exploiting Bluetooth and multimedia messaging services (MMS) follow markedly different spreading patterns. The Bluetooth virus can reach all susceptible handsets, but spreads relatively slowly, as its spread is driven by human mobility. In contrast, an MMS virus can spread rapidly, but because the underlying social network is fragmented, it can reach only a small fraction of all susceptible users. This difference affects both their spreading rate, the number of infected users, as well as the defense measures one needs to take to protect the system against potential viral outbreak.

[Perception of Primary Care physicians on the integration with cardiology through continuity of healthcare programs in secondary prevention].

PubMed

Cosin-Sales, J; Orozco Beltrán, D; Ledesma Rodríguez, R; Barbon Ortiz Casado, A; Fernández, G

2018-02-17

To determine the perception of Primary Care (PC) physicians on the integration with cardiology (CA) through continuity of healthcare programs. A cross-sectional and multicentre study was conducted, in which a total of 200 PC physicians from all over Spain completed a qualitative survey that evaluated the level of integration with CA in secondary prevention. Physicians were grouped according to the level of PC-CA integration. The integration between CA and PC was good, but it was better in those centres with a higher integration (74.0% vs. 60.0%; p=.02) and in general, physicians considered that integration had improved (92.0% vs. 73.0%; p<.001). Almost all PC physicians received the hospital discharge report. The majority of the hospital discharge reports included recommendations about the CA and PC follow-up, control of risk factors, as well as the duration of secondary prevention treatment, with not significant differences according to the level of integration. In 55.8%, 63.6%, and 51.3% of hospital discharge reports, indications were given on when to perform the follow-up blood analysis, as well as information about returning to working life and sexual activity, respectively. The most common communication method was the paper-based report (75 vs. 84%; p=NS). The communication between healthcare levels was greater in those Primary Care centres with a higher level of integration, as well as periodicity of the communication and the satisfaction of physicians (80.0% vs. 63.0%; p=.005). The level of integration between PC and CA is, in general, satisfactory, but those centres with a higher level of integration benefit more from a greater communication and satisfaction. Copyright © 2018 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

Mobile-PKI Service Model for Ubiquitous Environment

NASA Astrophysics Data System (ADS)

Jeun, Inkyung; Chun, Kilsoo

One of the most important things in PKI(Public Key Infrastructure) is the private key management issue. The private key must be deal with safely for secure PKI service. Even though PKI service is usually used for identification and authentication of user in e-commerce, PKI service has many inconvenient factors. Especially, the fact that storage media of private key for PKI service is limited to PC hard disk drive or smart card users must always carry, gives an inconvenience to user and is not suitable in ubiquitous network. This paper suggests the digital signature service using a mobile phone(m-PKI service) which is suitable in future network. A mobile phone is the most widely used for personal communication means and has a characteristic of high movability. We can use the PKI service anytime and anywhere using m-PKI.

A PC-based bus monitor program for use with the transport systems research vehicle RS-232 communication interfaces

NASA Technical Reports Server (NTRS)

Easley, Wesley C.

1991-01-01

Experiment critical use of RS-232 data busses in the Transport Systems Research Vehicle (TSRV) operated by the Advanced Transport Operating Systems Program Office at the NASA Langley Research Center has recently increased. Each application utilizes a number of nonidentical computer and peripheral configurations and requires task specific software development. To aid these development tasks, an IBM PC-based RS-232 bus monitoring system was produced. It can simultaneously monitor two communication ports of a PC or clone, including the nonstandard bus expansion of the TSRV Grid laptop computers. Display occurs in a separate window for each port's input with binary display being selectable. A number of other features including binary log files, screen capture to files, and a full range of communication parameters are provided.

Progress report on the management of the NEA ISOE system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lazo, E.

1995-03-01

The Information System on Occupational Exposure (ISOE) was launched by the Organization for Economic Cooperation and Development (OECD), Nuclear Energy Agency (NEA) on 1 January, 1992, to facilitate the communication of dosimetric and ALARA implementation data among nuclear utilities around the world. After two years of operation the System has become a mature interactive network for transfer of data and experience. Currently, 37 utilities from 12 countries, representing 289 power plants, and 12 national regulatory authorities participate in ISOE. Agreements for cooperation also exist between the NEA and the Commission of the European Communities (CEC), and the Paris Center ofmore » the WOrld Association of Nuclear Operators (WANO-PC). In addition, the International Atomic Energy Agency (IAEA) is acting as a co-sponsor of ISOE for the participation of non-NEA member countries. Three Regional Technical Centres, Europe, Asia, and Non-NEA member countries, serve to administer the system. The ISOE Network is comprised of three data bases and a communications network at several levels. The three ISOE data bases include the following types of information: NEA1 - annual plant dosimetric information; NEA2 - plant operational characteristics for dose and dose rate reduction; and NEA3 - job specific ALARA practices and experiences. The ISOE communications network has matured greatly during 1992 and 1993. In addition to having access to the above mentioned data bases, participants may now solicit information on new subjects, through the Technical Centres, from all other participants on a real-time basis. Information Sheets on these studies are produced for distribution to all participants. In addition, Topical Reports on areas of interest are produced, and Topical Meetings are held annually.« less

INFIBRA: machine vision inspection of acrylic fiber production

NASA Astrophysics Data System (ADS)

Davies, Roger; Correia, Bento A. B.; Contreiras, Jose; Carvalho, Fernando D.

1998-10-01

This paper describes the implementation of INFIBRA, a machine vision system for the inspection of acrylic fiber production lines. The system was developed by INETI under a contract from Fisipe, Fibras Sinteticas de Portugal, S.A. At Fisipe there are ten production lines in continuous operation, each approximately 40 m in length. A team of operators used to perform periodic manual visual inspection of each line in conditions of high ambient temperature and humidity. It is not surprising that failures in the manual inspection process occurred with some frequency, with consequences that ranged from reduced fiber quality to production stoppages. The INFIBRA system architecture is a specialization of a generic, modular machine vision architecture based on a network of Personal Computers (PCs), each equipped with a low cost frame grabber. Each production line has a dedicated PC that performs automatic inspection, using specially designed metrology algorithms, via four video cameras located at key positions on the line. The cameras are mounted inside custom-built, hermetically sealed water-cooled housings to protect them from the unfriendly environment. The ten PCs, one for each production line, communicate with a central PC via a standard Ethernet connection. The operator controls all aspects of the inspection process, from configuration through to handling alarms, via a simple graphical interface on the central PC. At any time the operator can also view on the central PC's screen the live image from any one of the 40 cameras employed by the system.

Toward information management in corporations (4)

NASA Astrophysics Data System (ADS)

Yamamoto, Takeo

The roles of personal computers (PC's) and workstations (WS's) in developing the corporate information system is discussed. The history and state of art for PC's and WS's are reviewed. Checkpoints for introducing PC's and WS's are ; Japanese word-processing capabilities, multi-media capabilities and network capabilities.

Global and System-Specific Resting-State fMRI Fluctuations Are Uncorrelated: Principal Component Analysis Reveals Anti-Correlated Networks

PubMed Central

Carbonell, Felix; Bellec, Pierre

2011-01-01

Abstract The influence of the global average signal (GAS) on functional-magnetic resonance imaging (fMRI)–based resting-state functional connectivity is a matter of ongoing debate. The global average fluctuations increase the correlation between functional systems beyond the correlation that reflects their specific functional connectivity. Hence, removal of the GAS is a common practice for facilitating the observation of network-specific functional connectivity. This strategy relies on the implicit assumption of a linear-additive model according to which global fluctuations, irrespective of their origin, and network-specific fluctuations are super-positioned. However, removal of the GAS introduces spurious negative correlations between functional systems, bringing into question the validity of previous findings of negative correlations between fluctuations in the default-mode and the task-positive networks. Here we present an alternative method for estimating global fluctuations, immune to the complications associated with the GAS. Principal components analysis was applied to resting-state fMRI time-series. A global-signal effect estimator was defined as the principal component (PC) that correlated best with the GAS. The mean correlation coefficient between our proposed PC-based global effect estimator and the GAS was 0.97±0.05, demonstrating that our estimator successfully approximated the GAS. In 66 out of 68 runs, the PC that showed the highest correlation with the GAS was the first PC. Since PCs are orthogonal, our method provides an estimator of the global fluctuations, which is uncorrelated to the remaining, network-specific fluctuations. Moreover, unlike the regression of the GAS, the regression of the PC-based global effect estimator does not introduce spurious anti-correlations beyond the decrease in seed-based correlation values allowed by the assumed additive model. After regressing this PC-based estimator out of the original time-series, we observed robust anti-correlations between resting-state fluctuations in the default-mode and the task-positive networks. We conclude that resting-state global fluctuations and network-specific fluctuations are uncorrelated, supporting a Resting-State Linear-Additive Model. In addition, we conclude that the network-specific resting-state fluctuations of the default-mode and task-positive networks show artifact-free anti-correlations. PMID:22444074

Integrated Photonic Orbital Angular Momentum Multiplexing and Demultiplexing on Chip

DTIC Science & Technology

2014-10-31

OAM free space coherent communication link testbed. ECL: external cavity laser . EDFA: erbium-doped fiber amplifier. PC: polarization controller. ATT...wave (cw) laser centered at 1540 nm, followed by an erbium-doped fiber amplifier (EDFA), an I/Q modulator, and another EDFA. The I/Q modulator was...communication link testbed. ECL: external cavity laser . EDFA: erbium-doped fiber amplifier. PC: polarization controller. ATT: attenuator. BPF: bandpass filter

AIRNET: A real-time comunications network for aircraft

NASA Technical Reports Server (NTRS)

Weaver, Alfred C.; Cain, Brendan G.; Colvin, M. Alexander; Simoncic, Robert

1990-01-01

A real-time local area network was developed for use on aircraft and space vehicles. It uses token ring technology to provide high throughput, low latency, and high reliability. The system was implemented on PCs and PC/ATs operating on PCbus, and on Intel 8086/186/286/386s operating on Multibus. A standard IEEE 802.2 logical link control interface was provided to (optional) upper layer software; this permits the controls designer to utilize standard communications protocols (e.g., ISO, TCP/IP) if time permits, or to utilize a very fast link level protocol directly if speed is critical. Both unacknowledged datagram and reliable virtual circuit services are supported. A station operating an 8 MHz Intel 286 as a host can generate a sustained load of 1.8 megabits per second per station, and a 100-byte message can be delivered from the transmitter's user memory to the receiver's user memory, including all operating system and network overhead, in under 4 milliseconds.

A Method of Predicting Queuing at Library Online PCs

ERIC Educational Resources Information Center

Beranek, Lea G.

2006-01-01

On-campus networked personal computer (PC) usage at La Trobe University Library was surveyed during September 2005. The survey's objectives were to confirm peak usage times, to measure some of the relevant parameters of online PC usage, and to determine the effect that 24 new networked PCs had on service quality. The survey found that clients…

Supercomputers ready for use as discovery machines for neuroscience.

PubMed

Helias, Moritz; Kunkel, Susanne; Masumoto, Gen; Igarashi, Jun; Eppler, Jochen Martin; Ishii, Shin; Fukai, Tomoki; Morrison, Abigail; Diesmann, Markus

2012-01-01

NEST is a widely used tool to simulate biological spiking neural networks. Here we explain the improvements, guided by a mathematical model of memory consumption, that enable us to exploit for the first time the computational power of the K supercomputer for neuroscience. Multi-threaded components for wiring and simulation combine 8 cores per MPI process to achieve excellent scaling. K is capable of simulating networks corresponding to a brain area with 10(8) neurons and 10(12) synapses in the worst case scenario of random connectivity; for larger networks of the brain its hierarchical organization can be exploited to constrain the number of communicating computer nodes. We discuss the limits of the software technology, comparing maximum filling scaling plots for K and the JUGENE BG/P system. The usability of these machines for network simulations has become comparable to running simulations on a single PC. Turn-around times in the range of minutes even for the largest systems enable a quasi interactive working style and render simulations on this scale a practical tool for computational neuroscience.

Supercomputers Ready for Use as Discovery Machines for Neuroscience

PubMed Central

Helias, Moritz; Kunkel, Susanne; Masumoto, Gen; Igarashi, Jun; Eppler, Jochen Martin; Ishii, Shin; Fukai, Tomoki; Morrison, Abigail; Diesmann, Markus

2012-01-01

NEST is a widely used tool to simulate biological spiking neural networks. Here we explain the improvements, guided by a mathematical model of memory consumption, that enable us to exploit for the first time the computational power of the K supercomputer for neuroscience. Multi-threaded components for wiring and simulation combine 8 cores per MPI process to achieve excellent scaling. K is capable of simulating networks corresponding to a brain area with 108 neurons and 1012 synapses in the worst case scenario of random connectivity; for larger networks of the brain its hierarchical organization can be exploited to constrain the number of communicating computer nodes. We discuss the limits of the software technology, comparing maximum filling scaling plots for K and the JUGENE BG/P system. The usability of these machines for network simulations has become comparable to running simulations on a single PC. Turn-around times in the range of minutes even for the largest systems enable a quasi interactive working style and render simulations on this scale a practical tool for computational neuroscience. PMID:23129998

Competing Contact Processes on Homogeneous Networks with Tunable Clusterization

NASA Astrophysics Data System (ADS)

Rybak, Marcin; Kułakowski, Krzysztof

2013-03-01

We investigate two homogeneous networks: the Watts-Strogatz network with mean degree ⟨k⟩ = 4 and the Erdös-Rényi network with ⟨k⟩ = 10. In both kinds of networks, the clustering coefficient C is a tunable control parameter. The network is an area of two competing contact processes, where nodes can be in two states, S or D. A node S becomes D with probability 1 if at least two its mutually linked neighbors are D. A node D becomes S with a given probability p if at least one of its neighbors is S. The competition between the processes is described by a phase diagram, where the critical probability pc depends on the clustering coefficient C. For p > pc the rate of state S increases in time, seemingly to dominate in the whole system. Below pc, the majority of nodes is in the D-state. The numerical results indicate that for the Watts-Strogatz network the D-process is activated at the finite value of the clustering coefficient C, close to 0.3. On the contrary, for the Erdös-Rényi network the transition is observed at the whole investigated range of C.

Communication During Palliative Care and End of Life: Perceptions of Experienced Pediatric Oncology Nurses.

PubMed

Montgomery, Kathleen E; Sawin, Kathleen J; Hendricks-Ferguson, Verna

Communication between patients, families, and healthcare providers is a central component of end-of-life care. Nurse communication during palliative care (PC) and end of life (EOL) is a phenomenon with limited research. It is unclear how the level of nursing experience influences the perspectives of nurses communicating during EOL. The aim of this study is to describe the commonalities of experienced nurses' perceptions of communicating during PC and EOL and perceptions of barriers and facilitators to effective communication. This study was part of a larger multisite study that used a qualitative, empirical phenomenology design and represents focus group data gathered from pediatric oncology nurses with more than 5 years of experience or who were advanced practice nurses not involved in the direct evaluation of other nurses. Five core themes with corresponding themes and subthemes were identified. The core themes included (a) Evolution of PC/EOL, (b) Skill of Knowing, (c) Expanded Essence of Caring, (d) Experienced Nurse as Committed Advocate, and (e) Valuing Individual Response to Grief. Findings reflect how the concept of experience transcended the 5 core themes and captured how experience provided nurses the know-how to fulfill the roles of communication, caring, and advocacy for children and families. Enhancing nurse communication skills during EOL requires opportunities to gain experience coupled with clinical strategies, such as standardized curricula, simulation, competency-based orientation programs, mentorship, and peer support.

Remodeling Pearson's Correlation for Functional Brain Network Estimation and Autism Spectrum Disorder Identification

PubMed Central

Li, Weikai; Wang, Zhengxia; Zhang, Limei; Qiao, Lishan; Shen, Dinggang

2017-01-01

Functional brain network (FBN) has been becoming an increasingly important way to model the statistical dependence among neural time courses of brain, and provides effective imaging biomarkers for diagnosis of some neurological or psychological disorders. Currently, Pearson's Correlation (PC) is the simplest and most widely-used method in constructing FBNs. Despite its advantages in statistical meaning and calculated performance, the PC tends to result in a FBN with dense connections. Therefore, in practice, the PC-based FBN needs to be sparsified by removing weak (potential noisy) connections. However, such a scheme depends on a hard-threshold without enough flexibility. Different from this traditional strategy, in this paper, we propose a new approach for estimating FBNs by remodeling PC as an optimization problem, which provides a way to incorporate biological/physical priors into the FBNs. In particular, we introduce an L1-norm regularizer into the optimization model for obtaining a sparse solution. Compared with the hard-threshold scheme, the proposed framework gives an elegant mathematical formulation for sparsifying PC-based networks. More importantly, it provides a platform to encode other biological/physical priors into the PC-based FBNs. To further illustrate the flexibility of the proposed method, we extend the model to a weighted counterpart for learning both sparse and scale-free networks, and then conduct experiments to identify autism spectrum disorders (ASD) from normal controls (NC) based on the constructed FBNs. Consequently, we achieved an 81.52% classification accuracy which outperforms the baseline and state-of-the-art methods. PMID:28912708

Distributed Software for Observations in the Near Infrared

NASA Astrophysics Data System (ADS)

Gavryusev, V.; Baffa, C.; Giani, E.

We have developed an integrated system that performs astronomical observations in Near Infrared bands operating two-dimensional instruments at the Italian National Infrared Facility's \\htmllink{ARNICA}{http://helios.arcetri.astro.it:/home/idefix/Mosaic/ instr/arnica/arnica.html} and \\htmllink{LONGSP}{http://helios.arcetri.astro.it:/home/idefix/Mosaic/ instr/longsp/longsp.html}. This software consists of several communicating processes, generally executed across a network, as well as on a single computer. The user interface is organized as widget-based X11 client. The interprocess communication is provided by sockets and uses TCP/IP. The processes denoted for control of hardware (telescope and other instruments) should be executed currently on a PC dedicated for this task under DESQview/X, while all other components (user interface, tools for the data analysis, etc.) can also work under UNIX\\@. The hardware independent part of software is based on the Athena Widget Set and is compiled by GNU C to provide maximum portability.

Remote control of the industry processes. POWERLINK protocol application

NASA Astrophysics Data System (ADS)

Wóbel, A.; Paruzel, D.; Paszkiewicz, B.

2017-08-01

The present technological development enables the use of solutions characterized by a lower failure rate, and work with greater precision. This allows you to obtain the most efficient production, high speed production and reliability of individual components. The main scope of this article was POWERLINK protocol application for communication with the controller B & R through communication Ethernet for recording process parameters. This enables control of run production cycle using an internal network connected to the PC industry. Knowledge of the most important parameters of the production in real time allows detecting of a failure immediately after occurrence. For this purpose, the position of diagnostic use driver X20CP1301 B&R to record measurement data such as pressure, temperature valve between the parties and the torque required to change the valve setting was made. The use of POWERLINK protocol allows for the transmission of information on the status of every 200 μs.

Prediction of proprotein convertase cleavage sites.

PubMed

Duckert, Peter; Brunak, Søren; Blom, Nikolaj

2004-01-01

Many secretory proteins and peptides are synthesized as inactive precursors that in addition to signal peptide cleavage undergo post-translational processing to become biologically active polypeptides. Precursors are usually cleaved at sites composed of single or paired basic amino acid residues by members of the subtilisin/kexin-like proprotein convertase (PC) family. In mammals, seven members have been identified, with furin being the one first discovered and best characterized. Recently, the involvement of furin in diseases ranging from Alzheimer's disease and cancer to anthrax and Ebola fever has created additional focus on proprotein processing. We have developed a method for prediction of cleavage sites for PCs based on artificial neural networks. Two different types of neural networks have been constructed: a furin-specific network based on experimental results derived from the literature, and a general PC-specific network trained on data from the Swiss-Prot protein database. The method predicts cleavage sites in independent sequences with a sensitivity of 95% for the furin neural network and 62% for the general PC network. The ProP method is made publicly available at http://www.cbs.dtu.dk/services/ProP.

Wireless local area networking for linking a PC reporting system and PACS: clinical feasibility in emergency reporting.

PubMed

Yoshihiro, Akiko; Nakata, Norio; Harada, Junta; Tada, Shimpei

2002-01-01

Although local area networks (LANs) are commonplace in hospital-based radiology departments today, wireless LANs are still relatively unknown and untried. A linked wireless reporting system was developed to improve work throughput and efficiency. It allows radiologists, physicians, and technologists to review current radiology reports and images and instantly compare them with reports and images from previous examinations. This reporting system also facilitates creation of teaching files quickly, easily, and accurately. It consists of a Digital Imaging and Communications in Medicine 3.0-based picture archiving and communication system (PACS), a diagnostic report server, and portable laptop computers. The PACS interfaces with magnetic resonance imagers, computed tomographic scanners, and computed radiography equipment. The same kind of functionality is achievable with a wireless LAN as with a wired LAN, with comparable bandwidth but with less cabling infrastructure required. This wireless system is presently incorporated into the operations of the emergency and radiology departments, with future plans calling for applications in operating rooms, outpatient departments, all hospital wards, and intensive care units. No major problems have been encountered with the system, which is in constant use and appears to be quite successful. Copyright RSNA, 2002

Network image data bank prototype: the RSI project (Resume de Sortie Images)

NASA Astrophysics Data System (ADS)

Abouchi, Nacer; Jourlin, Michel; Bohbot, Oriana; Faurie, Catherine; Grisel, Richard

1995-02-01

The Hospital Edouard Herriot in Lyon and 3M company, associated with the Electronic Department of Physics Chimics and Electronic Engineering School (CPE), decided in 1993 to begin a study on a project of image network. This project is composed of many practical applications to be checked one by one. The purpose of this paper is to discuss the context, which is kind of small picture archiving and communication system (PACS), to explain the methodology which has been used related to hardware and software implementation, and to give examples of the first results obtained. One of the main interests of the results is the possibility to obtain on the same support, 3M laser imager, a film including images from different modalities and abstract summing up the patient stay in the hospital. The framework used is built around Omnis7 and C++ language on a PC computer.

Service oriented network architecture for control and management of home appliances

NASA Astrophysics Data System (ADS)

Hayakawa, Hiroshi; Koita, Takahiro; Sato, Kenya

2005-12-01

Recent advances in multimedia network systems and mechatronics have led to the development of a new generation of applications that associate the use of various multimedia objects with the behavior of multiple robotic actors. The connection of audio and video devices through high speed multimedia networks is expected to make the system more convenient to use. For example, many home appliances, such as a video camera, a display monitor, a video recorder, an audio system and so on, are being equipped with a communication interface in the near future. Recently some platforms (i.e. UPnP1, HAVi2 and so on) are proposed for constructing home networks; however, there are some issues to be solved to realize various services by connecting different equipment via the pervasive peer-to-peer network. UPnP offers network connectivity of PCs of intelligent home appliances, practically, which means to require a PC in the network to control other devices. Meanwhile, HAVi has been developed for intelligent AV equipments with sophisticated functions using high CPU power and large memory. Considering the targets of home alliances are embedded systems, this situation raises issues of software and hardware complexity, cost, power consumption and so on. In this study, we have proposed and developed the service oriented network architecture for control and management of home appliances, named SONICA (Service Oriented Network Interoperability for Component Adaptation), to address these issues described before.

Transforming PC Power Supplies into Smart Car Battery Conditioners

ERIC Educational Resources Information Center

Rodriguez-Ascariz, J. M.; Boquete-Vazquez, L.

2011-01-01

This paper describes a laboratory project consisting of a PC power supply modification into an intelligent car-battery conditioner with both wireless and wired networking capabilities. Adding a microcontroller to an average PC power supply transforms it into a flexible, intelligent device that can be configured and that is suitable to keep car…

Stability and Topology of Scale-Free Networks under Attack and Defense Strategies

NASA Astrophysics Data System (ADS)

Gallos, Lazaros K.; Cohen, Reuven; Argyrakis, Panos; Bunde, Armin; Havlin, Shlomo

2005-05-01

We study tolerance and topology of random scale-free networks under attack and defense strategies that depend on the degree k of the nodes. This situation occurs, for example, when the robustness of a node depends on its degree or in an intentional attack with insufficient knowledge of the network. We determine, for all strategies, the critical fraction pc of nodes that must be removed for disintegrating the network. We find that, for an intentional attack, little knowledge of the well-connected sites is sufficient to strongly reduce pc. At criticality, the topology of the network depends on the removal strategy, implying that different strategies may lead to different kinds of percolation transitions.

NASA's Agency-Wide Strategy for Environmental Regulatory Risk Analysis and Communication

NASA Technical Reports Server (NTRS)

Scroggins, Sharon; Duda, Kristen

2008-01-01

This viewgraph presentation gives an overview of NASA's risk analysis communication programs associated with changing environmental policies. The topics include: 1) NASA Program Transition; 2) Principal Center for Regulatory Risk Analysis and Communication (RRAC PC); and 3) Regulatory Tracking and Communication Process.

Continuous GPS observations in Tohoku University and recovery effort after the 2011 off the Pacific coast of Tohoku Earthquake

NASA Astrophysics Data System (ADS)

Demachi, T.; Miura, S.; Ohta, Y.; Tachibana, K.; Ueki, S.; Sato, T.; Ohzono, M.; Umino, N.

2012-04-01

The nation-wide GPS observation network which is named GPS Earth Observation Network System (GEONET) has been established by the Geospatial Information Authority of Japan (GSI) (Miyazaki et al., 1997). The network composed more than 1,200 stations with baseline length is about 20-25 km. Tohoku University has also conducted continuous GPS observations since 1987 in the Tohoku district, Northeastern Japan (Miura et al., 1993). Recently, to investigate short-length crustal deformations such as volcanic deformation, co- and post-seismic deformation of M6-7 class earthquakes and inter-seismic deformations, we have deployed continuous GPS observation stations to complement the location of GEONET stations (Miura et al. 2000, 2002, and 2004). We installed GPS receiver, PC for data logging (ALIX series, PC Engines GmbH) and re-booter (e.g., WATCH BOOT nino, Meikyo Electric Co., Ltd.) in each station. We have secure and stable online access to each station from our university (Sendai city, Japan) using IP-VPN over fixed telephone lines (FLET'S Office service, Nippon Telegraph and Telephone East Corp.). Through this network, the data are transferred to our university and we can restart the devices if the devices hang up. Since 2010, we have tried to use on-line system through internet by prepaid mobile data-communication (b-mobile3G and b-mobileSIM U300, Japan Communications Inc.) in eight observation stations. Compared with the FLET'S Office service, we can conveniently and inexpensively establish wherever the mobile phone service is provided. The two stations are located in volcanoes, we activate the network system for an hour in every day using motor time switch, because of these devices are operated by limited DC power supplies through solar cell. In other six stations, we can use commercial AC power supplies, so that data connections are always available. On March 11, 2011, the 2011 off the Pacific coast of Tohoku Earthquake (Mw 9.0) occurred and a huge tsunami caused more than 19,000 dead and missing. After the main shock, the electricity failure and communication failure occurred in almost entire the Tohoku district. We obtained the GPS data of co-seismic and immediately after the main shock in only about 10% of our stations. Our observations resumed automatically in inland area as the electricity supply was resumed, while near the Pacific coastal area, recovery efforts were needed on site for resuming the observations. We carried out recovery effort in this area after March 20 when the essential utilities were almost repaired in Sendai city except tsunami-hit area. We used DC power supplies through solar cell and batteries and the prepaid mobile data-communication to operate GPS receivers and transfer data. This system is very useful in the area where fixed telephone and electric wires aren't reconstructed, because of the service of mobile phone is restored faster than fixed telephone service. We could resume the observations in almost all of our stations by April 1. Currently, we have been constructing redundant system of power supply using batteries to avoid data missing owing to electricity failure. We need to construct redundant network system in future.

Research on parallel combinatory spread spectrum communication system with double information matching

NASA Astrophysics Data System (ADS)

Xue, Wei; Wang, Qi; Wang, Tianyu

2018-04-01

This paper presents an improved parallel combinatory spread spectrum (PC/SS) communication system with the method of double information matching (DIM). Compared with conventional PC/SS system, the new model inherits the advantage of high transmission speed, large information capacity and high security. Besides, the problem traditional system will face is the high bit error rate (BER) and since its data-sequence mapping algorithm. Hence the new model presented shows lower BER and higher efficiency by its optimization of mapping algorithm.

NASA's Agency-Wide Strategy for Environmental Regulatory Risk Analysis and Communication

NASA Technical Reports Server (NTRS)

Duda, Kristen; Scroggins, Sharon

2008-01-01

NASA's mission is to pioneer the future in space exploration, scientific discovery, and aeronautics research. To help enable existing and future programs to pursue this mission, NASA has established the Principal Center for Regulatory Risk Analysis and Communication (RRAC PC) to proactively identify, analyze, and communicate environmental regulatory risks to the NASA community. The RRAC PC is chartered to evaluate the risks posed to NASA Programs and facilities by environmentally related drivers. The RRAC PC focuses on emerging environmental regulations, as well as risks related to operational changes that can trigger existing environmental requirements. Changing regulations have the potential to directly affect program activities. For example, regulatory changes can restrict certain activities or operations by mandating changes in how operations may be done or limiting where or how certain operations can take place. Regulatory changes also can directly affect the ability to use certain materials by mandating a production phase-out or restricting usage applications of certain materials. Such changes can result in NASA undertaking material replacement efforts. Even if a regulation does not directly affect NASA operations, U.S. and international regulations can pose program risks indirectly through requirements levied on manufacturers and vendors of components and materials. For example, manufacturers can change their formulations to comply with new regulatory requirements. Such changes can require time-consuming and costly requalification certification for use in human spaceflight programs. The RRAC PC has implemented several strategies for proactively managing regulatory change to minimize potential adverse impacts to NASA Programs and facilities. This presentation highlights the lessons learned through establishing the RRAC PC, the process by which the RRAC PC monitors and distributes information about emerging regulatory requirements, and the cross-Agency cooperation that is vital to supporting NASA's mission.

NASA's Agency-wide Strategy for Environmental Regulatory Risk Analysis and Communication

NASA Technical Reports Server (NTRS)

Duda, Kristen; Scroggins. Sharon

2008-01-01

NASA's mission is to pioneer the future in space exploration, scientific discovery, and aeronautics research. To help enable existing and future programs to pursue this mission, NASA has established the Principal Center for Regulatory Risk Analysis and Communication (RRAC PC) to proactively identify, analyze, and communicate environmental regulatory risks to the NASA community. The RRAC PC is chartered to evaluate the risks posed to NASA Programs and facilities by environmentally related drivers. The RRAC PC focuses on emerging environmental regulations, as well as risks related to operational changes that can trigger existing environmental requirements. Changing regulations have the potential to directly affect program activities. For example, regulatory changes can restrict certain activities or operations by mandating changes in how operations may be done or limiting where or how certain operations can take place. Regulatory changes also can directly affect the ability to use certain materials by mandating a production phase-out or restricting usage aPi'iications of certain materials. Such changes can result in NASA undertaking material replacement efforts. Even if a regulation does not directly affect NASA operations, U.S. and international regulations can pose program risks indirectly through requirements levied on manufacturers and vendors of components and materials. For example, manufacturers can change their formulations to comply with new regulatory requirements. Such changes can require time-consuming and costly requalification certification for use in human spaceflight programs. The RRAC PC has implemented several strategies for proactively managing regulatory change to minimize potential adverse impacts to NASA Programs and facilities. This presentation highlights the lessons learned through establishing the RRAC PC, the process by which the RRAC PC monitors and distributes information about emerging regulatory requirements, and the cross-Agency cooperation that is vital to supporting NASA's mission.

A theoretical framework for analyzing coupled neuronal networks: Application to the olfactory system.

PubMed

Barreiro, Andrea K; Gautam, Shree Hari; Shew, Woodrow L; Ly, Cheng

2017-10-01

Determining how synaptic coupling within and between regions is modulated during sensory processing is an important topic in neuroscience. Electrophysiological recordings provide detailed information about neural spiking but have traditionally been confined to a particular region or layer of cortex. Here we develop new theoretical methods to study interactions between and within two brain regions, based on experimental measurements of spiking activity simultaneously recorded from the two regions. By systematically comparing experimentally-obtained spiking statistics to (efficiently computed) model spike rate statistics, we identify regions in model parameter space that are consistent with the experimental data. We apply our new technique to dual micro-electrode array in vivo recordings from two distinct regions: olfactory bulb (OB) and anterior piriform cortex (PC). Our analysis predicts that: i) inhibition within the afferent region (OB) has to be weaker than the inhibition within PC, ii) excitation from PC to OB is generally stronger than excitation from OB to PC, iii) excitation from PC to OB and inhibition within PC have to both be relatively strong compared to presynaptic inputs from OB. These predictions are validated in a spiking neural network model of the OB-PC pathway that satisfies the many constraints from our experimental data. We find when the derived relationships are violated, the spiking statistics no longer satisfy the constraints from the data. In principle this modeling framework can be adapted to other systems and be used to investigate relationships between other neural attributes besides network connection strengths. Thus, this work can serve as a guide to further investigations into the relationships of various neural attributes within and across different regions during sensory processing.

Father's brain is sensitive to childcare experiences

PubMed Central

Abraham, Eyal; Hendler, Talma; Shapira-Lichter, Irit; Kanat-Maymon, Yaniv; Zagoory-Sharon, Orna; Feldman, Ruth

2014-01-01

Although contemporary socio-cultural changes dramatically increased fathers' involvement in childrearing, little is known about the brain basis of human fatherhood, its comparability with the maternal brain, and its sensitivity to caregiving experiences. We measured parental brain response to infant stimuli using functional MRI, oxytocin, and parenting behavior in three groups of parents (n = 89) raising their firstborn infant: heterosexual primary-caregiving mothers (PC-Mothers), heterosexual secondary-caregiving fathers (SC-Fathers), and primary-caregiving homosexual fathers (PC-Fathers) rearing infants without maternal involvement. Results revealed that parenting implemented a global “parental caregiving” neural network, mainly consistent across parents, which integrated functioning of two systems: the emotional processing network including subcortical and paralimbic structures associated with vigilance, salience, reward, and motivation, and mentalizing network involving frontopolar-medial-prefrontal and temporo-parietal circuits implicated in social understanding and cognitive empathy. These networks work in concert to imbue infant care with emotional salience, attune with the infant state, and plan adequate parenting. PC-Mothers showed greater activation in emotion processing structures, correlated with oxytocin and parent-infant synchrony, whereas SC-Fathers displayed greater activation in cortical circuits, associated with oxytocin and parenting. PC-Fathers exhibited high amygdala activation similar to PC-Mothers, alongside high activation of superior temporal sulcus (STS) comparable to SC-Fathers, and functional connectivity between amygdala and STS. Among all fathers, time spent in direct childcare was linked with the degree of amygdala-STS connectivity. Findings underscore the common neural basis of maternal and paternal care, chart brain–hormone–behavior pathways that support parenthood, and specify mechanisms of brain malleability with caregiving experiences in human fathers. PMID:24912146

DexterNet: An Open Platform for Heterogeneous Body Sensor Networks and Its Applications

DTIC Science & Technology

2008-12-19

motion, ECG PC, PDA 802.15.4 No No ALARM-NET pulse oximetry STARGATE Bluetooth No Yes [19] motion, ECG PDA, PC 802.11 (temperature, light, PIR) DexterNet...motion, ECG PDA 802.15.4 Yes Possible via SPINE EIP, GPS PC (e.g., air pollution sensor) MICAz, SHIMMER uses MICAz sensors and STARGATE to relay the

DDN (Defence Data Network) Protocol Implementations and Vendors Guide

DTIC Science & Technology

1988-08-01

Artificial Intelligence Laboratory Room NE43-723 545 Technology Square Cambridge, MA 02139 (617) 253-8843 S John Wroclawski, (JTW@AI.AJ.MIT.EDU...Massachusetts Institute of Technology Artificial Intelligence Laboratory Room NE43-743 545 Technology Square 0 Cambridge, MA 02139 (617) 253-7885 ORDERING...TCP/IP Network Software for PC-DOS Systems CPU: IBM-PC/XT/AT/compatible in conjunction with EXOS 205 Inteligent Ethernet Controller for PCbus 0/s

On the nature of hydrogen bonding between the phosphatidylcholine head group and water and dimethylsulfoxide

NASA Astrophysics Data System (ADS)

Dabkowska, Aleksandra P.; Lawrence, M. Jayne; McLain, Sylvia E.; Lorenz, Christian D.

2013-01-01

Molecular dynamics simulations are used to provide a detailed investigation of the hydrogen bond networks around the phosphatidylcholine (PC) head group in 1,2-dipropionyl-sn-glycero-3-phosphocholine in pure water, 10 mol.% and 30 mol.% dimethylsulfoxide (DMSO)-water solutions. Specifically, it is observed that DMSO replaces those water molecules that are within the first solvation shell of the choline, phosphate and ester groups of the PC head group, but are not hydrogen-bonded to the group. The effect of the presence of DMSO on the hydrogen bond network around the PC head groups of the lipid changes with the concentration of DMSO. In comparison to the hydrogen bond network observed in the pure water system, the number of hydrogen-bonded chains of solvent molecules increases slightly for the 10 mol.% DMSO system, while, in the 30 mol.% DMSO system, the number of hydrogen-bonded chains of solvent molecules decreases.

RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

PubMed Central

Rose, Nathan R; King, Hamish W; Blackledge, Neil P; Fursova, Nadezda A; Ember, Katherine JI; Fischer, Roman; Kessler, Benedikt M; Klose, Robert J

2016-01-01

Polycomb group (PcG) proteins function as chromatin-based transcriptional repressors that are essential for normal gene regulation during development. However, how these systems function to achieve transcriptional regulation remains very poorly understood. Here, we discover that the histone H2AK119 E3 ubiquitin ligase activity of Polycomb repressive complex 1 (PRC1) is defined by the composition of its catalytic subunits and is highly regulated by RYBP/YAF2-dependent stimulation. In mouse embryonic stem cells, RYBP plays a central role in shaping H2AK119 mono-ubiquitylation at PcG targets and underpins an activity-based communication between PRC1 and Polycomb repressive complex 2 (PRC2) which is required for normal histone H3 lysine 27 trimethylation (H3K27me3). Without normal histone modification-dependent communication between PRC1 and PRC2, repressive Polycomb chromatin domains can erode, rendering target genes susceptible to inappropriate gene expression signals. This suggests that activity-based communication and histone modification-dependent thresholds create a localized form of epigenetic memory required for normal PcG chromatin domain function in gene regulation. DOI: http://dx.doi.org/10.7554/eLife.18591.001 PMID:27705745

The Grim Reaper, Hounds of Hell, and Dr. Death: The Role of Storytelling for Palliative Care in Competing Medical Meaning Systems.

PubMed

Omilion-Hodges, Leah M; Swords, Nathan M

2017-10-01

Palliative care (PC) is a medical specialty that strives to fulfill the physical, psychosocial, emotional, practical, and spiritual needs of individuals at end of life or in tandem with curative treatment. Although exponentially rising in use and beneficial to patient well-being at end of life, the purpose of PC is often misunderstood and those providing its services frequently report resistance from organizational members. Such resistance can be attributed to tensions between traditional biomedical models of medicine that privilege curative treatment and biosocial models of medicine that holistically care for patients. Thus, this study addresses what tensions PC providers experience in their institutions and what communicative strategies they use at the interpersonal level in managing those tensions. Using structuration theory in tandem with relational dialectics theory, we inductively analyzed semistructured interviews with 24 Circle of Life award-winning PC providers. Findings indicate two dialectics experienced by PC providers in their institutions: the living-dying dialectic and the practicing-advocating dialectic. We conclude that these interpersonal dialectics emerge through interaction in competing medical meaning systems and found that storytelling was a particularly salient form of communication that participants used for management.

Long Pauses in Cerebellar Interneurons in Anesthetized Animals.

PubMed

Givon-Mayo, Ronit; Haar, Shlomi; Aminov, Yoav; Simons, Esther; Donchin, Opher

2017-04-01

Are long pauses in the firing of cerebellar interneurons (CINs) related to Purkinje cell (PC) pauses? If PC pauses affect the larger network, then we should find a close relationship between CIN pauses and those in PCs. We recorded activity of 241 cerebellar cortical neurons (206 CINs and 35 PCs) in three anesthetized cats. One fifth of the CINs and more than half of the PCs were identified as pausing. Pauses in CINs and PCs showed some differences: CIN mean pause length was shorter, and, after pauses, only CINs had sustained reduction in their firing rate (FR). Almost all pausing CINs fell into same cluster when we used different methods of clustering CINs by their spontaneous activity. The mean spontaneous firing rate of that cluster was approximately 53 Hz. We also examined cross-correlations in simultaneously recorded neurons. Of 39 cell pairs examined, 14 (35 %) had cross-correlations significantly different from those expected by chance. Almost half of the pairs with two CINs showed statistically significant negative correlations. In contrast, PC/CIN pairs did not often show significant effects in the cross-correlation (12/15 pairs). However, for both CIN/CIN and PC/CIN pairs, pauses in one unit tended to correspond to a reduction in the firing rate of the adjacent unit. In our view, our results support the possibility that previously reported PC bistability is part of a larger network response and not merely a biophysical property of PCs. Any functional role for PC bistability should probably be sought in the context of the broader network.

A Complete Image Management and Communications Network for the Neuroradiology Service at Georgetown University Hospital

NASA Astrophysics Data System (ADS)

Horii, Steven C.; Muraki, Alan; Mallon-Ingeholm, Mary L.; Mun, Seong K.; Clark, Letitia; Schellinger, Dieter

1989-05-01

A complete image management and communications system has been installed at Georgetown University Hospital (GUH). The network is based on the A T & T CommView System. In the Neuroradiology Division, this comprehensive network supports a multiscreen workstation with access to multiple imaging modalities such as CT and MRI from both the hospital and a remote imaging center. In addition, the radiologist can access these images from various workstations located throughout the hospital as well as from remote sites such as the home. Among the radiology services supported by the network, neuroradiology has the greatest need for such a system with extensive daily requirements involving the remote imaging center and on-line consultation around the clock. By providing neuroradiology with all available communication links, the radiologist can monitor, diagnose, and consult. The remote site has a subsystem capable of acquiring images and transmitting them over a high speed T1 data circuit. The GUH neuroradiologist can view these images on the neuro workstation or any of the workstations available in the Hospital. Fast and easy access to the images allows a radiologist to monitor multiple examinations as well as to utilize the workstation for diagnosis. To provide the neuroradiologist quick access to images at all times, a PC-based Results Viewing Station (RVS) has been placed in a doctor's home. Images may be sent to the RVS, or the user may request images from the central database at the hospital. Images can be viewed at home either as they are transmitted, or following transfer of a whole study. The efficiency and effectiveness of the system's capabilities with special regard to remote and teleradiology (RVS) operations have been studied for the neuroradiology service. This paper will discuss the current clinical acceptance and use, problems in implementation, and ways these difficulties are being surmounted.

Enlightening discriminative network functional modules behind Principal Component Analysis separation in differential-omic science studies

PubMed Central

Ciucci, Sara; Ge, Yan; Durán, Claudio; Palladini, Alessandra; Jiménez-Jiménez, Víctor; Martínez-Sánchez, Luisa María; Wang, Yuting; Sales, Susanne; Shevchenko, Andrej; Poser, Steven W.; Herbig, Maik; Otto, Oliver; Androutsellis-Theotokis, Andreas; Guck, Jochen; Gerl, Mathias J.; Cannistraci, Carlo Vittorio

2017-01-01

Omic science is rapidly growing and one of the most employed techniques to explore differential patterns in omic datasets is principal component analysis (PCA). However, a method to enlighten the network of omic features that mostly contribute to the sample separation obtained by PCA is missing. An alternative is to build correlation networks between univariately-selected significant omic features, but this neglects the multivariate unsupervised feature compression responsible for the PCA sample segregation. Biologists and medical researchers often prefer effective methods that offer an immediate interpretation to complicated algorithms that in principle promise an improvement but in practice are difficult to be applied and interpreted. Here we present PC-corr: a simple algorithm that associates to any PCA segregation a discriminative network of features. Such network can be inspected in search of functional modules useful in the definition of combinatorial and multiscale biomarkers from multifaceted omic data in systems and precision biomedicine. We offer proofs of PC-corr efficacy on lipidomic, metagenomic, developmental genomic, population genetic, cancer promoteromic and cancer stem-cell mechanomic data. Finally, PC-corr is a general functional network inference approach that can be easily adopted for big data exploration in computer science and analysis of complex systems in physics. PMID:28287094

Systems biology approaches to pancreatic cancer detection, prevention and treatment.

PubMed

Alian, Osama M; Philip, Philip A; Sarkar, Fazlul H; Azmi, Asfar S

2014-01-01

Pancreatic cancer [PC] is a complex disease harboring multiple genetic alterations. It is now well known that deregulation in the expression and function of oncogenes and tumor suppressor genes contributes to the development and progression of PC. The last 40 years have not seen any major improvements in the dismal overall cure rate for PC where drug resistance is an emerging and recurring obstacle for successful treatment of PC. Additionally, the lack of molecular biomarkers for patient selection limits drug availabilities for tailored therapy for patients diagnosed with PC. The very high failure rate of new drugs in Phase III clinical trials in PC calls for a more robust pre-clinical and clinical testing of new compounds. In order to rationally choose combinations of targeted agents that may improve therapeutic outcome by overcoming drug resistance, one needs to apply newer research tools such as systems and network biology. These newer tools are expected to assist in the design of effective drug combinations for the treatment of PC and are expected to become an important part in any future clinical trials. In this review we will provide background information on the current state of PC research, the reasons for drug failure and how to overcome these issues using systems sciences. We conclude this review with an example on how systems and network methodologies can help in the design efficacious drug combinations for this deadly and by far incurable disease.

Is there any difference in survivorship of total hip arthroplasty with different bearing surfaces? A systematic review and network meta-analysis.

PubMed

Yin, Si; Zhang, Dangfeng; Du, Hui; Du, Heng; Yin, Zhanhai; Qiu, Yusheng

2015-01-01

Although many total hip bearing implants are widely used all over the world, simultaneous comparisons across the numerous available bearing surfaces are rare. The purpose of this study was to compare the survivorship of total hip arthroplasty (THA) with six available bearing implants. We conducted a systematic review of randomized controlled trials (RCTs) reporting survivorship or revision of ceramic-on-ceramic (CoC), ceramic-on-conventional polyethylene (CoPc), ceramic-on-highly-crosslinked polyethylene (CoPxl), metal-on-conventional polyethylene (MoPc), metal-on-highly-crosslinked polyethylene (MoPxl), or metal-on-metal (MoM) bearing implants. The synthesis of present evidence was performed by both the traditional direct-comparison meta-analysis and network meta-analysis. In total, 40 RCTs involving a total of 5321 THAs were identified. The pooled data of network meta-analysis showed no difference in relative risk (RR) of revision across CoC, CoPc, CoPxl and MoPxl bearings. However, the MoM bearing was demonstrated with a significant higher risk of revision compared with CoC (RR 5.10; 95% CI=1.62 to 16.81), CoPc (RR 4.80; 95% CI=1.29 to 17.09), or MoPxl (RR 3.85; 95% CI=1.16 to 14.29), and the MoPc bearing was indicated with a higher risk of revision compared with CoC (RR 2.83; 95% CI=1.20 to 6.63). The ranking probabilities of the effective interventions also revealed the inferiority of the MoM and MoPc implants in survivorship (both 0%, 95% CI=0% to 0%) compared with CoC (39%, 95% CI=0% to 100%), CoPc (33%, 95% CI=0% to 100%), CoPxl (7%, 95% CI=0% to 100%) or MoPxl (21%, 95% CI=0% to 100%). The present evidence indicated the similar performance in survivorship among CoC, CoPc, CoPxl and MoPxl bearing implants, and that all likely have superiority compared with the MoM and MoPc bearing implants in THA procedures. Long-term RCT data are required to confirm these conclusions and better inform clinical decisions.

Western State Hospital: implementing a MUMPS-based PC network.

PubMed

Russ, D C

1991-06-01

Western State Hospital, a state-administered 1,200-bed mental health institution near Tacoma, Wash., confronted the challenge of automating its large campus through the application of the Healthcare Integrated Information System (HIIS). It is the first adaptation of the Veterans Administration's Decentralized Hospital Computer Program software in a mental health institution of this size, and the first DHCP application to be installed on a PC client/server network in a large U.S. hospital.

Three dimensional living neural networks

NASA Astrophysics Data System (ADS)

Linnenberger, Anna; McLeod, Robert R.; Basta, Tamara; Stowell, Michael H. B.

2015-08-01

We investigate holographic optical tweezing combined with step-and-repeat maskless projection micro-stereolithography for fine control of 3D positioning of living cells within a 3D microstructured hydrogel grid. Samples were fabricated using three different cell lines; PC12, NT2/D1 and iPSC. PC12 cells are a rat cell line capable of differentiation into neuron-like cells NT2/D1 cells are a human cell line that exhibit biochemical and developmental properties similar to that of an early embryo and when exposed to retinoic acid the cells differentiate into human neurons useful for studies of human neurological disease. Finally induced pluripotent stem cells (iPSC) were utilized with the goal of future studies of neural networks fabricated from human iPSC derived neurons. Cells are positioned in the monomer solution with holographic optical tweezers at 1064 nm and then are encapsulated by photopolymerization of polyethylene glycol (PEG) hydrogels formed by thiol-ene photo-click chemistry via projection of a 512x512 spatial light modulator (SLM) illuminated at 405 nm. Fabricated samples are incubated in differentiation media such that cells cease to divide and begin to form axons or axon-like structures. By controlling the position of the cells within the encapsulating hydrogel structure the formation of the neural circuits is controlled. The samples fabricated with this system are a useful model for future studies of neural circuit formation, neurological disease, cellular communication, plasticity, and repair mechanisms.

Basic ICT adoption and use by general practitioners: an analysis of primary care systems in 31 European countries.

PubMed

De Rosis, Sabina; Seghieri, Chiara

2015-08-22

There is general consensus that appropriate development and use of information and communication technologies (ICT) are crucial in the delivery of effective primary care (PC). Several countries are defining policies to support and promote a structural change of the health care system through the introduction of ICT. This study analyses the state of development of basic ICT in PC systems of 31 European countries with the aim to describe the extent of, and main purposes for, computer use by General Practitioners (GPs) across Europe. Additionally, trends over time have been analysed. Descriptive statistical analysis was performed on data from the QUALICOPC (Quality and Costs of Primary Care in Europe) survey, to describe the geographic differences in the general use of computer, and in specific computerized clinical functions for different health-related purposes such as prescribing, medication checking, generating health records and research for medical information on the Internet. While all the countries have achieved a near-universal adoption of a computer in their primary care practices, with only a few countries near or under the boundary of 90 %, the computerisation of primary care clinical functions presents a wide variability of adoption within and among countries and, in several cases (such as in the southern and central-eastern Europe), a large room for improvement. At European level, more efforts could be done to support southern and central-eastern Europe in closing the gap in adoption and use of ICT in PC. In particular, more attention seems to be need on the current usages of the computer in PC, by focusing policies and actions on the improvement of the appropriate usages that can impact on quality and costs of PC and can facilitate an interconnected health care system. However, policies and investments seem necessary but not sufficient to achieve these goals. Organizational, behavioural and also networking aspects should be taken in consideration.

KSC-98pc485

NASA Image and Video Library

1998-04-16

KENNEDY SPACE CENTER, FLA. -- Two USA employees, Tim Seymour (at left) and Danny Brown (at right), look at the network signal processor (NSP) that was responsible for postponement of the launch of STS-90 on Apr. 16. The Space Shuttle Columbia's liftoff from Launch Pad 39B was postponed 24 hours due to difficulty with NSP No. 2 on the orbiter. This device formats data and voice communications between the ground and the Space Shuttle. The unit, which is located in the orbiter's mid-deck, was removed and replaced on Apr. 16. Mission managers first noticed the problem at about 3 a.m. during normal communications systems activation prior to tanking operations. As a result, work to load the external tank with the cryogenic propellants did not begin and launch postponement was made official at about 8:15 a.m. STS-90 is slated to be the launch of Neurolab, a nearly 17-day mission to examine the effects of spaceflight on the brain, spinal cord, peripheral nerves and sensory organs in the human body.

Jargon that Computes: Today's PC Terminology.

ERIC Educational Resources Information Center

Crawford, Walt

1997-01-01

Discusses PC (personal computer) and telecommunications terminology in context: Integrated Services Digital Network (ISDN); Asymmetric Digital Subscriber Line (ADSL); cable modems; satellite downloads; T1 and T3 lines; magnitudes ("giga-,""nano-"); Central Processing Unit (CPU); Random Access Memory (RAM); Universal Serial Bus…

Implementation of the force decomposition machine for molecular dynamics simulations.

PubMed

Borštnik, Urban; Miller, Benjamin T; Brooks, Bernard R; Janežič, Dušanka

2012-09-01

We present the design and implementation of the force decomposition machine (FDM), a cluster of personal computers (PCs) that is tailored to running molecular dynamics (MD) simulations using the distributed diagonal force decomposition (DDFD) parallelization method. The cluster interconnect architecture is optimized for the communication pattern of the DDFD method. Our implementation of the FDM relies on standard commodity components even for networking. Although the cluster is meant for DDFD MD simulations, it remains general enough for other parallel computations. An analysis of several MD simulation runs on both the FDM and a standard PC cluster demonstrates that the FDM's interconnect architecture provides a greater performance compared to a more general cluster interconnect. Copyright © 2012 Elsevier Inc. All rights reserved.

Space weather monitoring by ground-based means carried out in Polar Geophysical Center at Arctic and Antarctic Research Institute

NASA Astrophysics Data System (ADS)

Janzhura, Alexander

A real-time information on geophysical processes in polar regions is very important for goals of Space Weather monitoring by the ground-based means. The modern communication systems and computer technology makes it possible to collect and process the data from remote sites without significant delays. A new acquisition equipment based on microprocessor modules and reliable in hush climatic conditions was deployed at the Roshydromet networks of geophysical observations in Arctic and is deployed at observatories in Antarctic. A contemporary system for on-line collecting and transmitting the geophysical data from the Arctic and Antarctic stations to AARI has been realized and the Polar Geophysical Center (PGC) arranged at AARI ensures the near-real time processing and analyzing the geophysical information from 11 stations in Arctic and 5 stations in Antarctic. The space weather monitoring by the ground based means is one of the main tasks standing before the Polar Geophysical Center. As studies by Troshichev and Janzhura, [2012] showed, the PC index characterizing the polar cap magnetic activity appeared to be an adequate indicator of the solar wind energy that entered into the magnetosphere and the energy that is accumulating in the magnetosphere. A great advantage of the PC index application over other methods based on satellite data is a permanent on-line availability of information about magnetic activity in both northern and southern polar caps. A special procedure agreed between Arctic and Antarctic Research Institute (AARI) and Space Institute of the Danish Technical University (DTUSpace) ensures calculation of the unified PC index in quasi-real time by magnetic data from the Thule and Vostok stations (see public site: http://pc-index.org). The method for estimation of AL and Dst indices (as indicators of state of the disturbed magnetosphere) based on data on foregoing PC indices has been elaborated and testified in the Polar Geophysical Center. It is demonstrated that the PC index can be successfully used to monitor the state of the magnetosphere (space weather monitoring) and the readiness of the magnetosphere to producing substorm or storm (space weather nowcasting).

Fast detection of covert visuospatial attention using hybrid N2pc and SSVEP features

NASA Astrophysics Data System (ADS)

Xu, Minpeng; Wang, Yijun; Nakanishi, Masaki; Wang, Yu-Te; Qi, Hongzhi; Jung, Tzyy-Ping; Ming, Dong

2016-12-01

Objective. Detecting the shift of covert visuospatial attention (CVSA) is vital for gaze-independent brain-computer interfaces (BCIs), which might be the only communication approach for severely disabled patients who cannot move their eyes. Although previous studies had demonstrated that it is feasible to use CVSA-related electroencephalography (EEG) features to control a BCI system, the communication speed remains very low. This study aims to improve the speed and accuracy of CVSA detection by fusing EEG features of N2pc and steady-state visual evoked potential (SSVEP). Approach. A new paradigm was designed to code the left and right CVSA with the N2pc and SSVEP features, which were then decoded by a classification strategy based on canonical correlation analysis. Eleven subjects were recruited to perform an offline experiment in this study. Temporal waves, amplitudes, and topographies for brain responses related to N2pc and SSVEP were analyzed. The classification accuracy derived from the hybrid EEG features (SSVEP and N2pc) was compared with those using the single EEG features (SSVEP or N2pc). Main results. The N2pc could be significantly enhanced under certain conditions of SSVEP modulations. The hybrid EEG features achieved significantly higher accuracy than the single features. It obtained an average accuracy of 72.9% by using a data length of 400 ms after the attention shift. Moreover, the average accuracy reached ˜80% (peak values above 90%) when using 2 s long data. Significance. The results indicate that the combination of N2pc and SSVEP is effective for fast detection of CVSA. The proposed method could be a promising approach for implementing a gaze-independent BCI.

A feasibility study of dementia communication training based on the VERA framework for pre-registration nurses: Part II impact on student experience.

PubMed

Naughton, Corina; Beard, Chloe; Tzouvara, Vasiliki; Pegram, Anne; Verity, Rebecca; Eley, Rhiannon; Hingley, David

2018-04-01

People living with dementia have complex communication needs, especially during acute hospital admissions. The VERA framework (validation, emotion, reassurance, activity) was designed to promote person centred communication between student nurses and people living with dementia, but there is limited evaluation of its impact. To measure the impact of dementia communication training (based on VERA) plus older adult unit (OAU) placement on students' ability to recognise opportunities for person centred (PC) communication compared to OAU placement alone. A control pre-post-study design was used. Dementia communication training plus follow-up during OAU placement was delivered to 51 students (5 OAU, two hospitals) while 66 students (7 OAUs, five hospitals) acted as controls. The primary outcome was students' ability to recognise PC communication assessed using case vignettes. Data were collected using electronic survey and focus group interviews. Data analysis used independent non-parametric Mann-Whitney U test and thematic analysis. In total 52 students (response rate 40%) completed surveys at the end of placements (38 intervention, 14 control group students). In the intervention group, participants were significantly more likely to identify PC responses with a mean score of 10.5 (SD 3.0) compared with 7.5 (SD 3.0) in the control group (p = 0.006). In focus group interviews (n = 19 students), the main themes were connecting with patients, VERA in practice, communication challenges, and learning environment. VERA was described as a flexible approach that added to participants' communication toolkit. The learning environment, complexity of patients and organisational resources were important contextual factors. The VERA framework has potential as a foundation level dementia communication training intervention, but it requires more rigorous testing. Nursing can lead the way in developing and embedding evidence-based, interdisciplinary dementia communication training in preregistration curricula. Copyright © 2018 Elsevier Ltd. All rights reserved.

A Science Cloud: OneSpaceNet

NASA Astrophysics Data System (ADS)

Morikawa, Y.; Murata, K. T.; Watari, S.; Kato, H.; Yamamoto, K.; Inoue, S.; Tsubouchi, K.; Fukazawa, K.; Kimura, E.; Tatebe, O.; Shimojo, S.

2010-12-01

Main methodologies of Solar-Terrestrial Physics (STP) so far are theoretical, experimental and observational, and computer simulation approaches. Recently "informatics" is expected as a new (fourth) approach to the STP studies. Informatics is a methodology to analyze large-scale data (observation data and computer simulation data) to obtain new findings using a variety of data processing techniques. At NICT (National Institute of Information and Communications Technology, Japan) we are now developing a new research environment named "OneSpaceNet". The OneSpaceNet is a cloud-computing environment specialized for science works, which connects many researchers with high-speed network (JGN: Japan Gigabit Network). The JGN is a wide-area back-born network operated by NICT; it provides 10G network and many access points (AP) over Japan. The OneSpaceNet also provides with rich computer resources for research studies, such as super-computers, large-scale data storage area, licensed applications, visualization devices (like tiled display wall: TDW), database/DBMS, cluster computers (4-8 nodes) for data processing and communication devices. What is amazing in use of the science cloud is that a user simply prepares a terminal (low-cost PC). Once connecting the PC to JGN2plus, the user can make full use of the rich resources of the science cloud. Using communication devices, such as video-conference system, streaming and reflector servers, and media-players, the users on the OneSpaceNet can make research communications as if they belong to a same (one) laboratory: they are members of a virtual laboratory. The specification of the computer resources on the OneSpaceNet is as follows: The size of data storage we have developed so far is almost 1PB. The number of the data files managed on the cloud storage is getting larger and now more than 40,000,000. What is notable is that the disks forming the large-scale storage are distributed to 5 data centers over Japan (but the storage system performs as one disk). There are three supercomputers allocated on the cloud, one from Tokyo, one from Osaka and the other from Nagoya. One's simulation job data on any supercomputers are saved on the cloud data storage (same directory); it is a kind of virtual computing environment. The tiled display wall has 36 panels acting as one display; the pixel (resolution) size of it is as large as 18000x4300. This size is enough to preview or analyze the large-scale computer simulation data. It also allows us to take a look of multiple (e.g., 100 pictures) on one screen together with many researchers. In our talk we also present a brief report of the initial results using the OneSpaceNet for Global MHD simulations as an example of successful use of our science cloud; (i) Ultra-high time resolution visualization of Global MHD simulations on the large-scale storage and parallel processing system on the cloud, (ii) Database of real-time Global MHD simulation and statistic analyses of the data, and (iii) 3D Web service of Global MHD simulations.

[Integration of the Internet into medical education].

PubMed

Taradi, Suncana Kukolja

2002-01-01

The Internet promises dramatic changes in the way we learn and teach, the way we interact as a society. Networked technologies introduce interactivity and multimedia into the educational process. The student of the 21st century will use his/her PC as a learning station, as a tutoring system, as an information provider and as a communication center. Therefore the passive classroom (teacher-centered teaching) will evolve into active studio learning (student-centered learning). This will be achieved by new teaching techniques and standards of quality. The role of the new generation of educators is to create exploratory learning environments that offer a wide range of views on many subject areas and encourage active lifelong learning. This will be achieved by 1) placing courseware on the web where it can be accessed by remote students and by 2) finding and reviewing teaching materials obtained from www for possible integration into the local lecture material. The paper suggests strategies for introducing medical educators to networked teaching.

High resolution ultrasonic spectroscopy system for nondestructive evaluation

NASA Technical Reports Server (NTRS)

Chen, C. H.

1991-01-01

With increased demand for high resolution ultrasonic evaluation, computer based systems or work stations become essential. The ultrasonic spectroscopy method of nondestructive evaluation (NDE) was used to develop a high resolution ultrasonic inspection system supported by modern signal processing, pattern recognition, and neural network technologies. The basic system which was completed consists of a 386/20 MHz PC (IBM AT compatible), a pulser/receiver, a digital oscilloscope with serial and parallel communications to the computer, an immersion tank with motor control of X-Y axis movement, and the supporting software package, IUNDE, for interactive ultrasonic evaluation. Although the hardware components are commercially available, the software development is entirely original. By integrating signal processing, pattern recognition, maximum entropy spectral analysis, and artificial neural network functions into the system, many NDE tasks can be performed. The high resolution graphics capability provides visualization of complex NDE problems. The phase 3 efforts involve intensive marketing of the software package and collaborative work with industrial sectors.

Fast data transmission from serial data acquisition for the GEM detector system

NASA Astrophysics Data System (ADS)

Kolasinski, Piotr; Pozniak, Krzysztof T.; Czarski, Tomasz; Byszuk, Adrian; Chernyshova, Maryna; Kasprowicz, Grzegorz; Krawczyk, Rafal D.; Wojenski, Andrzej; Zabolotny, Wojciech

2015-09-01

This article proposes new method of storing data and transferring it to PC in the X-ray GEM detector system. The whole process is performed by FPGA chips (Spartan-6 series from Xilinx). Comparing to previous methods, new approach allows to store much more data in the system. New, improved implementation of the communication algorithm significantly increases transfer rate between system and PC. In PC data is merged and processed by MATLAB. The structure of firmware implemented in the FPGAs is described.

PC-CUBE: A Personal Computer Based Hypercube

NASA Technical Reports Server (NTRS)

Ho, Alex; Fox, Geoffrey; Walker, David; Snyder, Scott; Chang, Douglas; Chen, Stanley; Breaden, Matt; Cole, Terry

1988-01-01

PC-CUBE is an ensemble of IBM PCs or close compatibles connected in the hypercube topology with ordinary computer cables. Communication occurs at the rate of 115.2 K-band via the RS-232 serial links. Available for PC-CUBE is the Crystalline Operating System III (CrOS III), Mercury Operating System, CUBIX and PLOTIX which are parallel I/O and graphics libraries. A CrOS performance monitor was developed to facilitate the measurement of communication and computation time of a program and their effects on performance. Also available are CXLISP, a parallel version of the XLISP interpreter; GRAFIX, some graphics routines for the EGA and CGA; and a general execution profiler for determining execution time spent by program subroutines. PC-CUBE provides a programming environment similar to all hypercube systems running CrOS III, Mercury and CUBIX. In addition, every node (personal computer) has its own graphics display monitor and storage devices. These allow data to be displayed or stored at every processor, which has much instructional value and enables easier debugging of applications. Some application programs which are taken from the book Solving Problems on Concurrent Processors (Fox 88) were implemented with graphics enhancement on PC-CUBE. The applications range from solving the Mandelbrot set, Laplace equation, wave equation, long range force interaction, to WaTor, an ecological simulation.

Starch and antioxidant compound release during in vitro gastrointestinal digestion of gluten-free pasta.

PubMed

Camelo-Méndez, Gustavo A; Agama-Acevedo, Edith; Rosell, Cristina M; de J Perea-Flores, Maria; Bello-Pérez, Luis A

2018-10-15

The microstructure of cooked gluten-free pasta depends on the ingredients used, and this microstructure affects the starch hydrolysis (SH), the release of phenolic compounds (PC) and their antioxidant capacity (AC). The aim of this study was to evaluate the SD and bioaccessibility of PC during in vitro gastrointestinal digestion of gluten-free pasta and its relationship with the microstructure. The highest SH was during the intestinal phase (≈60%), but pasta with the highest content of unripe plantain and chickpea presented the lowest release of PC (≈60%). The insoluble dietary fibre could be responsible (≈12.5%) for these effects. The cooked pasta showed high AC in the intestinal phase. Regions with gelatinized starch granules in a less dense protein network and other regions with intact or swollen granules surrounded by a protein network were observed. The starch digestion and bioaccessibility of PC were related to the structure of the matrix. Copyright © 2018 Elsevier Ltd. All rights reserved.

Establishing a communications link between two different, incompatible, personal computers: with practical examples and illustrations and program code.

PubMed

Davidson, R W

1985-01-01

The increasing need to communicate to exchange data can be handled by personal microcomputers. The necessity for the transference of information stored in one type of personal computer to another type of personal computer is often encountered in the process of integrating multiple sources of information stored in different and incompatible computers in Medical Research and Practice. A practical example is demonstrated with two relatively inexpensive commonly used computers, the IBM PC jr. and the Apple IIe. The basic input/output (I/O) interface chip for serial communication for each computer are joined together using a Null connector and cable to form a communications link. Using BASIC (Beginner's All-purpose Symbolic Instruction Code) Computer Language and the Disk Operating System (DOS) the communications handshaking protocol and file transfer is established between the two computers. The BASIC programming languages used are Applesoft (Apple Personal Computer) and PC BASIC (IBM Personal computer).

Neural network-based system for pattern recognition through a fiber optic bundle

NASA Astrophysics Data System (ADS)

Gamo-Aranda, Javier; Rodriguez-Horche, Paloma; Merchan-Palacios, Miguel; Rosales-Herrera, Pablo; Rodriguez, M.

2001-04-01

A neural network based system to identify images transmitted through a Coherent Fiber-optic Bundle (CFB) is presented. Patterns are generated in a computer, displayed on a Spatial Light Modulator, imaged onto the input face of the CFB, and recovered optically by a CCD sensor array for further processing. Input and output optical subsystems were designed and used to that end. The recognition step of the transmitted patterns is made by a powerful, widely-used, neural network simulator running on the control PC. A complete PC-based interface was developed to control the different tasks involved in the system. An optical analysis of the system capabilities was carried out prior to performing the recognition step. Several neural network topologies were tested, and the corresponding numerical results are also presented and discussed.

Smart cards: a specific application in the hospital.

PubMed

Güler, I; Zengin, R M; Sönmez, M

1998-12-01

Computers have the ability to process and access tremendous amounts of information in our daily lives. But, now, individuals have this ability by carrying a smart card in their own wallets. These cards provide us the versatility, power, and security of computers. This study begins with a short description of smart cards and their advantages. Then, an electronic circuit that is designed for healthcare application in hospitals is introduced. This circuit functions as a smart card holder identifier, access controller for hospital doors and also can be used as a smart card reader/writer. Design steps of this electronic circuit, operation principles, serial communication with P.C., and the software are examined. Finally a complete access control network for hospital doors that functions with smart cards is discussed.

Network analysis of ChIP-Seq data reveals key genes in prostate cancer.

PubMed

Zhang, Yu; Huang, Zhen; Zhu, Zhiqiang; Liu, Jianwei; Zheng, Xin; Zhang, Yuhai

2014-09-03

Prostate cancer (PC) is the second most common cancer among men in the United States, and it imposes a considerable threat to human health. A deep understanding of its underlying molecular mechanisms is the premise for developing effective targeted therapies. Recently, deep transcriptional sequencing has been used as an effective genomic assay to obtain insights into diseases and may be helpful in the study of PC. In present study, ChIP-Seq data for PC and normal samples were compared, and differential peaks identified, based upon fold changes (with P-values calculated with t-tests). Annotations of these peaks were performed. Protein-protein interaction (PPI) network analysis was performed with BioGRID and constructed with Cytoscape, following which the highly connected genes were screened. We obtained a total of 5,570 differential peaks, including 3,726 differentially enriched peaks in tumor samples and 1,844 differentially enriched peaks in normal samples. There were eight significant regions of the peaks. The intergenic region possessed the highest score (51%), followed by intronic (31%) and exonic (11%) regions. The analysis revealed the top 35 highly connected genes, which comprised 33 differential genes (such as YWHAQ, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein and θ polypeptide) from ChIP-Seq data and 2 differential genes retrieved from the PPI network: UBA52 (ubiquitin A-52 residue ribosomal protein fusion product (1) and SUMO2 (SMT3 suppressor of mif two 3 homolog (2) . Our findings regarding potential PC-related genes increase the understanding of PC and provides direction for future research.

OCEAN-PC and a distributed network for ocean data

NASA Technical Reports Server (NTRS)

Mclain, Douglas R.

1992-01-01

The Intergovernmental Oceanographic Commission (IOC) wishes to develop an integrated software package for oceanographic data entry and access in developing countries. The software, called 'OCEAN-PC', would run on low cost PC microcomputers and would encourage and standardize: (1) entry of local ocean observations; (2) quality control of the local data; (3) merging local data with historical data; (4) improved display and analysis of the merged data; and (5) international data exchange. OCEAN-PC will link existing MS-DOS oceanographic programs and data sets with table-driven format conversions. Since many ocean data sets are now being distributed on optical discs (Compact Discs - Read Only Memory, CD-ROM, Mass et al. 1987), OCEAN-PC will emphasize access to CD-ROMs.

Gene Expression Network Reconstruction by Convex Feature Selection when Incorporating Genetic Perturbations

PubMed Central

Logsdon, Benjamin A.; Mezey, Jason

2010-01-01

Cellular gene expression measurements contain regulatory information that can be used to discover novel network relationships. Here, we present a new algorithm for network reconstruction powered by the adaptive lasso, a theoretically and empirically well-behaved method for selecting the regulatory features of a network. Any algorithms designed for network discovery that make use of directed probabilistic graphs require perturbations, produced by either experiments or naturally occurring genetic variation, to successfully infer unique regulatory relationships from gene expression data. Our approach makes use of appropriately selected cis-expression Quantitative Trait Loci (cis-eQTL), which provide a sufficient set of independent perturbations for maximum network resolution. We compare the performance of our network reconstruction algorithm to four other approaches: the PC-algorithm, QTLnet, the QDG algorithm, and the NEO algorithm, all of which have been used to reconstruct directed networks among phenotypes leveraging QTL. We show that the adaptive lasso can outperform these algorithms for networks of ten genes and ten cis-eQTL, and is competitive with the QDG algorithm for networks with thirty genes and thirty cis-eQTL, with rich topologies and hundreds of samples. Using this novel approach, we identify unique sets of directed relationships in Saccharomyces cerevisiae when analyzing genome-wide gene expression data for an intercross between a wild strain and a lab strain. We recover novel putative network relationships between a tyrosine biosynthesis gene (TYR1), and genes involved in endocytosis (RCY1), the spindle checkpoint (BUB2), sulfonate catabolism (JLP1), and cell-cell communication (PRM7). Our algorithm provides a synthesis of feature selection methods and graphical model theory that has the potential to reveal new directed regulatory relationships from the analysis of population level genetic and gene expression data. PMID:21152011

Single software platform used for high speed data transfer implementation in a 65k pixel camera working in single photon counting mode

NASA Astrophysics Data System (ADS)

Maj, P.; Kasiński, K.; Gryboś, P.; Szczygieł, R.; Kozioł, A.

2015-12-01

Integrated circuits designed for specific applications generally use non-standard communication methods. Hybrid pixel detector readout electronics produces a huge amount of data as a result of number of frames per seconds. The data needs to be transmitted to a higher level system without limiting the ASIC's capabilities. Nowadays, the Camera Link interface is still one of the fastest communication methods, allowing transmission speeds up to 800 MB/s. In order to communicate between a higher level system and the ASIC with a dedicated protocol, an FPGA with dedicated code is required. The configuration data is received from the PC and written to the ASIC. At the same time, the same FPGA should be able to transmit the data from the ASIC to the PC at the very high speed. The camera should be an embedded system enabling autonomous operation and self-monitoring. In the presented solution, at least three different hardware platforms are used—FPGA, microprocessor with real-time operating system and the PC with end-user software. We present the use of a single software platform for high speed data transfer from 65k pixel camera to the personal computer.

Active site formation mechanism of carbon-based oxygen reduction catalysts derived from a hyperbranched iron phthalocyanine polymer.

PubMed

Hiraike, Yusuke; Saito, Makoto; Niwa, Hideharu; Kobayashi, Masaki; Harada, Yoshihisa; Oshima, Masaharu; Kim, Jaehong; Nabae, Yuta; Kakimoto, Masa-Aki

2015-01-01

Carbon-based cathode catalysts derived from a hyperbranched iron phthalocyanine polymer (HB-FePc) were characterized, and their active-site formation mechanism was studied by synchrotron-based spectroscopy. The properties of the HB-FePc catalyst are compared with those of a catalyst with high oxygen reduction reaction (ORR) activity synthesized from a mixture of iron phthalocyanine and phenolic resin (FePc/PhRs). Electrochemical measurements demonstrate that the HB-FePc catalyst does not lose its ORR activity up to 900°C, whereas that of the FePc/PhRs catalyst decreases above 700°C. Hard X-ray photoemission spectra reveal that the HB-FePc catalysts retain more nitrogen components than the FePc/PhRs catalysts between pyrolysis temperatures of 600°C and 800°C. This is because the linked structure of the HB-FePc precursor has high thermostability against nitrogen desorption. Consequently, effective doping of active nitrogen species into the sp (2) carbon network of the HB-FePc catalysts may occur up to 900°C.

Tailoring the visual communication of climate projections for local adaptation practitioners in Germany and the UK

PubMed Central

Lorenz, Susanne; Dessai, Suraje; Forster, Piers M.; Paavola, Jouni

2015-01-01

Visualizations are widely used in the communication of climate projections. However, their effectiveness has rarely been assessed among their target audience. Given recent calls to increase the usability of climate information through the tailoring of climate projections, it is imperative to assess the effectiveness of different visualizations. This paper explores the complexities of tailoring through an online survey conducted with 162 local adaptation practitioners in Germany and the UK. The survey examined respondents’ assessed and perceived comprehension (PC) of visual representations of climate projections as well as preferences for using different visualizations in communicating and planning for a changing climate. Comprehension and use are tested using four different graph formats, which are split into two pairs. Within each pair the information content is the same but is visualized differently. We show that even within a fairly homogeneous user group, such as local adaptation practitioners, there are clear differences in respondents’ comprehension of and preference for visualizations. We do not find a consistent association between assessed comprehension and PC or use within the two pairs of visualizations that we analysed. There is, however, a clear link between PC and use of graph format. This suggests that respondents use what they think they understand the best, rather than what they actually understand the best. These findings highlight that audience-specific targeted communication may be more complex and challenging than previously recognized. PMID:26460109

The effects of persuasive communication and planning on intentions to be more physically active and on physical activity behaviour among low-active adolescents.

PubMed

Tessier, Damien; Sarrazin, Philippe; Nicaise, Virginie; Dupont, Jean-Philippe

2015-01-01

The purpose of the present study was to examine, using the theory of planned behaviour (TPB) combined with a self-regulatory behaviour change approach, whether persuasive communication based on adolescents' salient beliefs (SBCondition) and planning (PCondition) could promote the intention and physical activity (PA) behaviour of low-active adolescents participating in less than 1 h/day of moderate-to-vigorous physical activity. The protocol tested the effectiveness of two strategies used separately (i.e. SBC or PC) or in combination (i.e. CC = NSBC-SBC-PC) compared to a group receiving a message based on non-salient beliefs (NSBCondition). The 116 low-active students from ten 10th and 11th grade classes were assigned, using a cluster randomisation, into one of the four conditions (i.e. NSBC, SBC, PC and CC). Baseline data were collected two weeks before the intervention. The post-test data collection occurred directly after the intervention, and the follow-up took place two weeks later. Results showed that (1) the NSBC was the least effective strategy, (2) the SBC had no significant effect on PA behaviour and the TPB variables, (3) the PC had no significant effect on PA behaviour but increased the intention and perceived behavioural control and (4) the effects of the PC and the CC were not significantly different.

Evaluation of the Communication Between Arachnoid Cysts and Neighboring Cerebrospinal Fluid Spaces by T2W 3D-SPACE With Variant Flip-Angle Technique at 3 T.

PubMed

Algin, Oktay

2018-05-21

Phase-contrast cine magnetic resonance imaging (PC-MRI) is a widely used technique for determination of possible communication of arachnoid cysts (ACs). Three-dimensional (3D) sampling perfection with application-optimized contrasts using different flip-angle evolutions (3D-SPACE) technique is a relatively new method for 3D isotropic scanning of the entire cranium within a short time. In this research, the usage of the 3D-SPACE technique in differentiation of communicating or noncommunicating type ACs was evaluated. Thirty-five ACs in 34 patients were retrospectively examined. The 3D-SPACE, PC-MRI, and contrast material-enhanced cisternography (if present) images of the patients were analyzed. Each cyst was described according to cyst size/location, third ventricle diameter, Evans index, and presence of hydrocephalus. Communication was defined as absent (score 0), suspected (score 1), or present (score 2) on each sequence. Results of PC-MRI or cisternography (if available) examinations were used as criterion standard techniques to categorize all cysts as communicating or noncommunicating type. The results of 3D-SPACE were compared with criterion standard techniques. The comparisons between groups were performed using Mann-Whitney and Fisher exact tests. For demonstration of communication status of the cysts, criterion standard test results and 3D-SPACE findings were almost in perfect harmony (κ[95% confidence interval: 0.94]; P < 0.001). When evaluating the communicative properties, 3D-SPACE findings correlated with other final results at a rate of 97%. There is a positive correlation with third ventricular diameters and Evans index for all patients (r = 0.77, P < 0.001). For other analyzed variables, there is no significant difference or correlation between the groups. The 3D-SPACE technique is an easy, useful, and noninvasive alternative for the evaluation of morphology, topographical relationships, and communication status of ACs.

Implementation of NCCN Palliative Care Guidelines by member institutions.

PubMed

Albizu-Rivera, Alexandra; Portman, Diane G; Thirlwell, Sarah; Codada, Shirley N; Donovan, Kristine A

2016-02-01

Increasingly, evidence suggests the integration of palliative care (PC) with standard oncologic care can yield substantial benefits. As part of an effort to improve the PC of cancer patients, the National Comprehensive Cancer Network (NCCN) has developed clinical practice guidelines for PC that promote access to quality, evidence-based PC. This study sought to characterize current implementation of the guidelines by NCCN member institutions. Institutional representatives appointed to the NCCN Palliative Care Guidelines Panel were asked to complete an online survey in the spring of 2014. The survey focused on availability of PC services, screening and referral practices for PC, PC education, and quality improvement programs. The survey was completed by representatives from 21 of 25 NCCN member institutions (84 %). A majority routinely provides PC services via interdisciplinary teams; 52 % routinely inform patients of the availability, elements, and benefits of PC. The guidelines are most often used to guide clinical practice; only 10 % reported using the guidelines to formally screen for PC needs and/or make referrals to PC specialists. Among the 62 % of institutions that screen any patients using any available criteria, when a patient screens positive for PC needs, a referral to a PC specialist is made less than half the time. Implementation of PC Guidelines is incomplete and various aspects of the guidelines, such as the recommendation to screen all patients for PC needs, are applied inconsistently. Despite this, most institutions provide PC services in a manner consistent with the guidelines. Greater implementation of the guidelines' recommendations is needed.

Retreatment of Recurrent Internal Carotid-Posterior Communicating Artery Aneurysm after Coil Embolization

PubMed Central

TOYOTA, Shingo; TAKI, Takuyu; WAKAYAMA, Akatsuki; YOSHIMINE, Toshiki

2015-01-01

Internal carotid-posterior communicating artery (IC-PC) aneurysms account for more than 20% of all intracranial aneurysms. As a result of the increase in coiling, there has also been an increase in recurrent IC-PC aneurysms after coiling. We present our experience of 10 recurrent IC-PC aneurysms after coiling that were retreated using surgical or endovascular techniques in order to discuss the choice of treatment and the points of clipping without removal of coils. From 2007 to 2014, 10 recurrent IC-PC aneurysms after coiling were retreated. When the previous frames covered the aneurysms all around or almost around except a part of the neck, coiling was chosen. In other cases, clipping was chosen. Clipping was attempted without removal of coils when it was technically feasible. Among the 10 IC-PC aneurysms retreated, 3 were retreated with coiling and 7 were retreated with clipping. In all three cases retreated with coiling, almost complete occlusion was accomplished. In the seven cases retreated with clipping, coil extrusion was observed during surgery in six cases. In most of them, it was necessary to dissect strong adhesions around the coiled aneurysms and to utilize temporary occlusion of the internal carotid artery. In all seven cases, neck clipping was accomplished without the removal of coils. There were no neurological complications in any cases. The management of recurrent lesions of embolized IC-PC aneurysms requires appropriate choice of treatment using both coiling and clipping. Clipping, especially without the removal of coils, plays an important role in safe treatment. PMID:26437796

Retreatment of Recurrent Internal Carotid-Posterior Communicating Artery Aneurysm after Coil Embolization.

PubMed

Toyota, Shingo; Taki, Takuyu; Wakayama, Akatsuki; Yoshimine, Toshiki

2015-01-01

Internal carotid-posterior communicating artery (IC-PC) aneurysms account for more than 20% of all intracranial aneurysms. As a result of the increase in coiling, there has also been an increase in recurrent IC-PC aneurysms after coiling. We present our experience of 10 recurrent IC-PC aneurysms after coiling that were retreated using surgical or endovascular techniques in order to discuss the choice of treatment and the points of clipping without removal of coils. From 2007 to 2014, 10 recurrent IC-PC aneurysms after coiling were retreated. When the previous frames covered the aneurysms all around or almost around except a part of the neck, coiling was chosen. In other cases, clipping was chosen. Clipping was attempted without removal of coils when it was technically feasible. Among the 10 IC-PC aneurysms retreated, 3 were retreated with coiling and 7 were retreated with clipping. In all three cases retreated with coiling, almost complete occlusion was accomplished. In the seven cases retreated with clipping, coil extrusion was observed during surgery in six cases. In most of them, it was necessary to dissect strong adhesions around the coiled aneurysms and to utilize temporary occlusion of the internal carotid artery. In all seven cases, neck clipping was accomplished without the removal of coils. There were no neurological complications in any cases. The management of recurrent lesions of embolized IC-PC aneurysms requires appropriate choice of treatment using both coiling and clipping. Clipping, especially without the removal of coils, plays an important role in safe treatment.

AMPS/PC - AUTOMATIC MANUFACTURING PROGRAMMING SYSTEM

NASA Technical Reports Server (NTRS)

Schroer, B. J.

1994-01-01

The AMPS/PC system is a simulation tool designed to aid the user in defining the specifications of a manufacturing environment and then automatically writing code for the target simulation language, GPSS/PC. The domain of problems that AMPS/PC can simulate are manufacturing assembly lines with subassembly lines and manufacturing cells. The user defines the problem domain by responding to the questions from the interface program. Based on the responses, the interface program creates an internal problem specification file. This file includes the manufacturing process network flow and the attributes for all stations, cells, and stock points. AMPS then uses the problem specification file as input for the automatic code generator program to produce a simulation program in the target language GPSS. The output of the generator program is the source code of the corresponding GPSS/PC simulation program. The system runs entirely on an IBM PC running PC DOS Version 2.0 or higher and is written in Turbo Pascal Version 4 requiring 640K memory and one 360K disk drive. To execute the GPSS program, the PC must have resident the GPSS/PC System Version 2.0 from Minuteman Software. The AMPS/PC program was developed in 1988.

Convergent RANK- and c-Met-mediated signaling components predict survival of patients with prostate cancer: an interracial comparative study.

PubMed

Hu, Peizhen; Chung, Leland W K; Berel, Dror; Frierson, Henry F; Yang, Hua; Liu, Chunyan; Wang, Ruoxiang; Li, Qinlong; Rogatko, Andre; Zhau, Haiyen E

2013-01-01

We reported (PLoS One 6 (12):e28670, 2011) that the activation of c-Met signaling in RANKL-overexpressing bone metastatic LNCaP cell and xenograft models increased expression of RANK, RANKL, c-Met, and phosphorylated c-Met, and mediated downstream signaling. We confirmed the significance of the RANK-mediated signaling network in castration resistant clinical human prostate cancer (PC) tissues. In this report, we used a multispectral quantum dot labeling technique to label six RANK and c-Met convergent signaling pathway mediators simultaneously in formalin fixed paraffin embedded (FFPE) tissue specimens, quantify the intensity of each expression at the sub-cellular level, and investigated their potential utility as predictors of patient survival in Caucasian-American, African-American and Chinese men. We found that RANKL and neuropilin-1 (NRP-1) expression predicts survival of Caucasian-Americans with PC. A Gleason score ≥ 8 combined with nuclear p-c-Met expression predicts survival in African-American PC patients. Neuropilin-1, p-NF-κB p65 and VEGF are predictors for the overall survival of Chinese men with PC. These results collectively support interracial differences in cell signaling networks that can predict the survival of PC patients.

Application of ZigBee sensor network to data acquisition and monitoring

NASA Astrophysics Data System (ADS)

Terada, Mitsugu

2009-01-01

A ZigBee sensor network for data acquisition and monitoring is presented in this paper. It is configured using a commercially available ZigBee solution. A ZigBee module is connected via a USB interface to a Microsoft Windows PC, which works as a base station in the sensor network. Data collected by remote devices are sent to the base station PC, which is set as a data sink. Each remote device is built of a commercially available ZigBee module product and a sensor. The sensor is a thermocouple connected to a cold junction compensator amplifier. The signal from the amplifier is input to an AD converter port on the ZigBee module. Temperature data are transmitted according to the ZigBee protocol from the remote device to the data sink PC. The data sampling rate is one sampling per second; the highest possible rate is four samplings per second. The data are recorded in the hexadecimal number format by device control software, and the data file is stored in text format on the data sink PC. Time-dependent data changes can be monitored using the macro function of spreadsheet software. The system is considered a useful tool in the field of education, based on the results of trial use for measurement in an undergraduate laboratory class at a university.

Surface-induced polymerization of actin.

PubMed Central

Renault, A; Lenne, P F; Zakri, C; Aradian, A; Vénien-Bryan, C; Amblard, F

1999-01-01

Living cells contain a very large amount of membrane surface area, which potentially influences the direction, the kinetics, and the localization of biochemical reactions. This paper quantitatively evaluates the possibility that a lipid monolayer can adsorb actin from a nonpolymerizing solution, induce its polymerization, and form a 2D network of individual actin filaments, in conditions that forbid bulk polymerization. G- and F-actin solutions were studied beneath saturated Langmuir monolayers containing phosphatidylcholine (PC, neutral) and stearylamine (SA, a positively charged surfactant) at PC:SA = 3:1 molar ratio. Ellipsometry, tensiometry, shear elastic measurements, electron microscopy, and dark-field light microscopy were used to characterize the adsorption kinetics and the interfacial polymerization of actin. In all cases studied, actin follows a monoexponential reaction-limited adsorption with similar time constants (approximately 10(3) s). At a longer time scale the shear elasticity of the monomeric actin adsorbate increases only in the presence of lipids, to a 2D shear elastic modulus of mu approximately 30 mN/m, indicating the formation of a structure coupled to the monolayer. Electron microscopy shows the formation of a 2D network of actin filaments at the PC:SA surface, and several arguments strongly suggest that this network is indeed causing the observed elasticity. Adsorption of F-actin to PC:SA leads more quickly to a slightly more rigid interface with a modulus of mu approximately 50 mN/m. PMID:10049338

Event-Based Sensing and Control for Remote Robot Guidance: An Experimental Case

PubMed Central

Santos, Carlos; Martínez-Rey, Miguel; Santiso, Enrique

2017-01-01

This paper describes the theoretical and practical foundations for remote control of a mobile robot for nonlinear trajectory tracking using an external localisation sensor. It constitutes a classical networked control system, whereby event-based techniques for both control and state estimation contribute to efficient use of communications and reduce sensor activity. Measurement requests are dictated by an event-based state estimator by setting an upper bound to the estimation error covariance matrix. The rest of the time, state prediction is carried out with the Unscented transformation. This prediction method makes it possible to select the appropriate instants at which to perform actuations on the robot so that guidance performance does not degrade below a certain threshold. Ultimately, we obtained a combined event-based control and estimation solution that drastically reduces communication accesses. The magnitude of this reduction is set according to the tracking error margin of a P3-DX robot following a nonlinear trajectory, remotely controlled with a mini PC and whose pose is detected by a camera sensor. PMID:28878144

Analysis of psychological factors for quality assessment of interactive multimodal service

NASA Astrophysics Data System (ADS)

Yamagishi, Kazuhisa; Hayashi, Takanori

2005-03-01

We proposed a subjective quality assessment model for interactive multimodal services. First, psychological factors of an audiovisual communication service were extracted by using the semantic differential (SD) technique and factor analysis. Forty subjects participated in subjective tests and performed point-to-point conversational tasks on a PC-based TV phone that exhibits various network qualities. The subjects assessed those qualities on the basis of 25 pairs of adjectives. Two psychological factors, i.e., an aesthetic feeling and a feeling of activity, were extracted from the results. Then, quality impairment factors affecting these two psychological factors were analyzed. We found that the aesthetic feeling is mainly affected by IP packet loss and video coding bit rate, and the feeling of activity depends on delay time and video frame rate. We then proposed an opinion model derived from the relationships among quality impairment factors, psychological factors, and overall quality. The results indicated that the estimation error of the proposed model is almost equivalent to the statistical reliability of the subjective score. Finally, using the proposed model, we discuss guidelines for quality design of interactive audiovisual communication services.

Thick Acellular Heart Extracellular Matrix with Inherent Vasculature: A Potential Platform for Myocardial Tissue Regeneration

PubMed Central

Sarig, Udi; Au-Yeung, Gigi C.T.; Wang, Yao; Bronshtein, Tomer; Dahan, Nitsan; Boey, Freddy Y.C.; Venkatraman, Subbu S.

2012-01-01

The decellularization of porcine heart tissue offers many opportunities for the production of physiologically relevant myocardial mimetic scaffolds. Earlier, we reported the successful isolation of a thin porcine cardiac extracellular matrix (pcECM) exhibiting relevant bio-mechanical properties for myocardial tissue engineering. Nevertheless, since native cardiac tissue is much thicker, such thin scaffolds may offer limited regeneration capacity. However, generation of thicker myocardial mimetic tissue constructs is hindered by diffusion limitations (∼100 μm), and the lack of a proper vascular-like network within these constructs. In our present work, we focused on optimizing the decellularization procedure for thicker tissue slabs (10–15 mm), while retaining their inherent vasculature, and on characterizing the resulting pcECM. The trypsin/Triton-based perfusion procedure that resulted in a nonimmunogenic and cell-supportive pcECM was found to be more effective in cell removal and in the preservation of fiber morphology and structural characteristics than stirring, sonication, or sodium dodecyl sulfate/Triton-based procedures. Mass spectroscopy revealed that the pcECM is mainly composed of ECM proteins with no apparent cellular protein remains. Mechanical testing indicated that the obtained pcECM is viscoelastic in nature and possesses the typical stress-strain profile of biological materials. It is stiffer than native tissue yet exhibits matched mechanical properties in terms of energy dissipation, toughness, and ultimate stress behavior. Vascular network functionality was maintained to the first three–four branches from the main coronary vessels. Taken together, these results reaffirm the efficiency of the decellularization procedure reported herein for yielding thick nonimmunogenic cell-supportive pcECM scaffolds, preserving both native tissue ultra-structural properties and an inherent vascular network. When reseeded with the appropriate progenitor cells, these scaffolds can potentially serve as ex vivo screening platforms for new therapeutics, as models for human cardiac ECM, or as biomedical constructs for patch or transmural transplantation strategies. PMID:22663095

CD-ROM source data uploaded to the operating and storage devices of an IBM 3090 mainframe through a PC terminal.

PubMed

Boros, L G; Lepow, C; Ruland, F; Starbuck, V; Jones, S; Flancbaum, L; Townsend, M C

1992-07-01

A powerful method of processing MEDLINE and CINAHL source data uploaded to the IBM 3090 mainframe computer through an IBM/PC is described. Data are first downloaded from the CD-ROM's PC devices to floppy disks. These disks then are uploaded to the mainframe computer through an IBM/PC equipped with WordPerfect text editor and computer network connection (SONNGATE). Before downloading, keywords specifying the information to be accessed are typed at the FIND prompt of the CD-ROM station. The resulting abstracts are downloaded into a file called DOWNLOAD.DOC. The floppy disks containing the information are simply carried to an IBM/PC which has a terminal emulation (TELNET) connection to the university-wide computer network (SONNET) at the Ohio State University Academic Computing Services (OSU ACS). The WordPerfect (5.1) processes and saves the text into DOS format. Using the File Transfer Protocol (FTP, 130,000 bytes/s) of SONNET, the entire text containing the information obtained through the MEDLINE and CINAHL search is transferred to the remote mainframe computer for further processing. At this point, abstracts in the specified area are ready for immediate access and multiple retrieval by any PC having network switch or dial-in connection after the USER ID, PASSWORD and ACCOUNT NUMBER are specified by the user. The system provides the user an on-line, very powerful and quick method of searching for words specifying: diseases, agents, experimental methods, animals, authors, and journals in the research area downloaded. The user can also copy the TItles, AUthors and SOurce with optional parts of abstracts into papers under edition. This arrangement serves the special demands of a research laboratory by handling MEDLINE and CINAHL source data resulting after a search is performed with keywords specified for ongoing projects. Since the Ohio State University has a centrally founded mainframe system, the data upload, storage and mainframe operations are free.

Dynamics of influence and social balance in spatially-embedded regular and random networks

NASA Astrophysics Data System (ADS)

Singh, P.; Sreenivasan, S.; Szymanski, B.; Korniss, G.

2015-03-01

Structural balance - the tendency of social relationship triads to prefer specific states of polarity - can be a fundamental driver of beliefs, behavior, and attitudes on social networks. Here we study how structural balance affects deradicalization in an otherwise polarized population of leftists and rightists constituting the nodes of a low-dimensional social network. Specifically, assuming an externally moderating influence that converts leftists or rightists to centrists with probability p, we study the critical value p =pc , below which the presence of metastable mixed population states exponentially delay the achievement of centrist consensus. Above the critical value, centrist consensus is the only fixed point. Complementing our previously shown results for complete graphs, we present results for the process on low-dimensional networks, and show that the low-dimensional embedding of the underlying network significantly affects the critical value of probability p. Intriguingly, on low-dimensional networks, the critical value pc can show non-monotonicity as the dimensionality of the network is varied. We conclude by analyzing the scaling behavior of temporal variation of unbalanced triad density in the network for different low-dimensional network topologies. Supported in part by ARL NS-CTA, ONR, and ARO.

Theory-of-mind-related neural activity for one’s romantic partner predicts partner well-being

PubMed Central

Felix, Steven; Yung, Matthew G.; Hooker, Christine I.

2016-01-01

Healthy social relationships are linked to myriad positive physical and mental health outcomes, raising the question of how to enhance relationship formation and quality. Behavioral data suggest that theory of mind (ToM) may be one such process. ToM is supported by a network of brain regions including the temporo-parietal junction (TPJ), medial prefrontal cortex and precuneus (PC). However, little research has investigated how the ToM network supports healthy social relationships. Here, we investigate whether recruitment of the ToM network when thinking about the mental states of one’s romantic partner predicts the partner’s well-being. We find that selectivity in left TPJ (LTPJ) and PC for beliefs vs physical attributes of one’s partner is positively associated with partner well-being the day of and day after a meaningful encounter. Furthermore, LTPJ and PC selectivity moderated how the partner’s perception of being understood during the encounter affected their later well-being. Finally, we find the association between ToM-related neural selectivity and well-being robust to other factors related to the relationship and the encounter. Together, these data suggest that selective engagement of the neural network supporting ToM may be a key ingredient for the development and maintenance of healthy romantic relationships. PMID:26609107

Key technology research of HILS based on real-time operating system

NASA Astrophysics Data System (ADS)

Wang, Fankai; Lu, Huiming; Liu, Che

2018-03-01

In order to solve the problems that the long development cycle of traditional simulation and digital simulation doesn't have the characteristics of real time, this paper designed a HILS(Hardware In the Loop Simulation) system based on the real-time operating platform xPC. This system solved the communication problems between HMI and Simulink models through the MATLAB engine interface, and realized the functions of system setting, offline simulation, model compiling and downloading, etc. Using xPC application interface and integrating the TeeChart ActiveX chart component to realize the monitoring function of real-time target application; Each functional block in the system is encapsulated in the form of DLL, and the data interaction between modules was realized by MySQL database technology. When the HILS system runs, search the address of the online xPC target by means of the Ping command, to establish the Tcp/IP communication between the two machines. The technical effectiveness of the developed system is verified through the typical power station control system.

W49A: A Massive Molecular Cloud Forming a Massive Star Cluster in the Galactic Disk

NASA Astrophysics Data System (ADS)

Galvan-Madrid, Roberto; Liu, Hauyu Baobab; Pineda, Jaime E.; Zhang, Zhi-Yu; Ginsburg, Adam; Roman-Zuñiga, Carlos; Peters, Thomas

2015-08-01

I summarize our current results of the MUSCLE survey of W49A, the most luminous star formation region in the Milky Way. Our approach emphasizes multi-scale, multi-resolution imaging in dust, ionized-, and molecular gas, to trace the multiple gas components from <0.1 pc (core scale) all the way up to the scale of the entire giant molecular cloud (GMC), ˜100 pc. The 106 M⊙ GMC is structured in a radial network of filaments that converges toward the central 'hub' with ˜2x105 M⊙, which contains within a few pc a deeply embedded young massive cluster (YMC) of stellar mass ~5x104 M⊙. We also discuss the dynamics of the filamentary network, the role of turbulence in the formation of this YMC, and how objects like W49A can link Milky Way and extragalactic star formation relations.

Address-event-based platform for bioinspired spiking systems

NASA Astrophysics Data System (ADS)

Jiménez-Fernández, A.; Luján, C. D.; Linares-Barranco, A.; Gómez-Rodríguez, F.; Rivas, M.; Jiménez, G.; Civit, A.

2007-05-01

Address Event Representation (AER) is an emergent neuromorphic interchip communication protocol that allows a real-time virtual massive connectivity between huge number neurons, located on different chips. By exploiting high speed digital communication circuits (with nano-seconds timings), synaptic neural connections can be time multiplexed, while neural activity signals (with mili-seconds timings) are sampled at low frequencies. Also, neurons generate "events" according to their activity levels. More active neurons generate more events per unit time, and access the interchip communication channel more frequently, while neurons with low activity consume less communication bandwidth. When building multi-chip muti-layered AER systems, it is absolutely necessary to have a computer interface that allows (a) reading AER interchip traffic into the computer and visualizing it on the screen, and (b) converting conventional frame-based video stream in the computer into AER and injecting it at some point of the AER structure. This is necessary for test and debugging of complex AER systems. In the other hand, the use of a commercial personal computer implies to depend on software tools and operating systems that can make the system slower and un-robust. This paper addresses the problem of communicating several AER based chips to compose a powerful processing system. The problem was discussed in the Neuromorphic Engineering Workshop of 2006. The platform is based basically on an embedded computer, a powerful FPGA and serial links, to make the system faster and be stand alone (independent from a PC). A new platform is presented that allow to connect up to eight AER based chips to a Spartan 3 4000 FPGA. The FPGA is responsible of the network communication based in Address-Event and, at the same time, to map and transform the address space of the traffic to implement a pre-processing. A MMU microprocessor (Intel XScale 400MHz Gumstix Connex computer) is also connected to the FPGA to allow the platform to implement eventbased algorithms to interact to the AER system, like control algorithms, network connectivity, USB support, etc. The LVDS transceiver allows a bandwidth of up to 1.32 Gbps, around ~66 Mega events per second (Mevps).

PCASSO: a design for secure communication of personal health information via the internet.

PubMed

Baker, D B; Masys, D R

1999-05-01

The Internet holds both promise and peril for the communications of person-identifiable health information. Because of technical features designed to promote accessibility and interoperability rather than security, Internet addressing conventions and transport protocols are vulnerable to compromise by malicious persons and programs. In addition, most commonly used personal computer (PC) operating systems currently lack the hardware-based system software protection and process isolation that are essential for ensuring the integrity of trusted applications. Security approaches designed for electronic commerce, that trade known security weaknesses for limited financial liability, are not sufficient for personal health data, where the personal damage caused by unintentional disclosure may be far more serious. To overcome these obstacles, we are developing and evaluating an Internet-based communications system called PCASSO (Patient-centered access to secure systems online) that applies state of the art security to health information. PCASSO includes role-based access control, multi-level security, strong device and user authentication, session-specific encryption and audit trails. Unlike Internet-based electronic commerce 'solutions,' PCASSO secures data end-to-end: in the server; in the data repository; across the network; and on the client. PCASSO is designed to give patients as well as providers access to personal health records via the Internet.

Tablet PC as a mobil PACS terminal using wireless LAN

NASA Astrophysics Data System (ADS)

Tsao, Bo-Shen; Ching, Yu-Tai; Lee, Wen-Jeng; Chen, Shyh-Jye; Chang, Chia-Hung; Chen, Chien-Jung; Yen, York; Lee, Yuan-Ten

2003-05-01

A PACS mobile terminal has applications in ward round, emergency room and remote teleradiology consultation. Personal Digital Assistants (PDAs) have the highest mobility and are used for many medical applications. However, their roles are limited in the field of radiology due to small screen size. In this study, we built a wireless PACS terminal using a hand-held tablet-PC. A tablet PC (X-pilot, LEO systems, Taiwan) running the WinCE operating systems was used as our mobile PACS terminal. This device is equipped with 800×600 resolution 10.4 inch TFT monitor. The network connection between the tablet PC and the server was linked via wireless LAN (IEEE 802.11b).

A PDA-based Network for Telemonitoring Asthma Triggering Gases in the El Paso School Districts of the US - Mexico Border Region.

PubMed

Shenoy, Namdev; Nazeran, Homer

2005-01-01

In this paper we describe the application of a personal digital assistant (PDA) or pocket PC as an effective communication device to telemonitor levels of asthma triggering gases collected from a remote location under test to a workstation which has a personal computer (PC) running on Windows XP® as the operating system. The Bluetooth® features of the PDA are explored to transmit data collected by a Direct™ Sense Tox toxic gas monitor equipped with five toxic gas probes and one temperature sensor in real time, thereby making this telemonitoring system an innovative instrument in monitoring levels of asthma triggering gases in the El Paso-border metropolitan region, a region in which asthma is highly prevalent especially in children. At the workstation or fixed location these readings are displayed using a custom made, user friendly graphical user interface (GUI) developed using software tools like action scripting with Macromedia® Flash™. The growing advancement in technology and ever diminishing sizes of handheld devices encouraged us to opt for this configuration. Moreover, the PDA and toxic gas monitor were also chosen for their light weight, portability, flexibility, low cost and data collection and transmission capabilities.

A major upgrade of the sediment echosounder ATLAS PARASOUND and the digital acquisition software ParaDigMA for high-resolution sea floor studies

NASA Astrophysics Data System (ADS)

Gerriets, A.; von Lom-Keil, H.; Spiess, V.; Zwanzig, C.; Bruns, R.

2003-04-01

The combination of the ATLAS PARASOUND sediment echosounder, designed by ATLAS Hydrographic, and the digital recording software package ParaDigMA (commercially available as ATLAS PARASTORE-3) for online digitisation, preprocessing and visualisation of recorded seismograms has proven to be a reliable system for high-resolution acoustic sea floor studies. During 10 years of successful operation aboard several research vessels, including R/V Meteor, R/V Sonne and R/V Polarstern, the system has been only slightly modified. Based on this experience, today's PARASOUND/ParaDigMA system has accomplished the step from DOS towards Windows platform and network capability. In cooperation of ATLAS Hydrographic and the Department of Earth Sciences, University of Bremen a major upgrade of the PARASOUND/ParaDigMA system has been developed that adds significant functionality for surveys of sediment structures and sea floor morphology. The innovations primarily concern the control section of the ATLAS PARASOUND echosounder and the ParaDigMA user front end. The previous analogue PARASOUND control terminal has been replaced by a small real time control PC responsible for the control of the echosounder as well as for the continuous digitisation of the data. The control PC communicates via standard network protocols metadata and data with client applications that can display and store the acquired data on different computers on the network. The new network capabilities of the system overcome former limitations and admit a high flexibility with respect to numbers and locations of operator and recording/display PCs. The system now offers a simultaneous parallel registration of the 2.5-5.5kHz parametric signal and the 18kHz NBS signal. This feature in combination with the recording of complete soundings including the entire water column provides the basis for evolving scientific research topics e. g. gas venting. The ParaDigMA recording software now operates on Windows platforms which provide sophisticated possibilities in data visualisation as well as improved methods in data handling. Former approved features as online plot of the preprocessed seismograms have been continued.

The Development of the Puerto Rico Lightning Detection Network for Meteorological Research

NASA Technical Reports Server (NTRS)

Legault, Marc D.; Miranda, Carmelo; Medin, J.; Ojeda, L. J.; Blakeslee, Richard J.

2011-01-01

A land-based Puerto Rico Lightning Detection Network (PR-LDN) dedicated to the academic research of meteorological phenomena has being developed. Five Boltek StormTracker PCI-Receivers with LTS-2 Timestamp Cards with GPS and lightning detectors were integrated to Pentium III PC-workstations running the CentOS linux operating system. The Boltek detector linux driver was compiled under CentOS, modified, and thoroughly tested. These PC-workstations with integrated lightning detectors were installed at five of the University of Puerto Rico (UPR) campuses distributed around the island of PR. The PC-workstations are left on permanently in order to monitor lightning activity at all times. Each is networked to their campus network-backbone permitting quasi-instantaneous data transfer to a central server at the UPR-Bayam n campus. Information generated by each lightning detector is managed by a C-program developed by us called the LDN-client. The LDN-client maintains an open connection to the central server operating the LDN-server program where data is sent real-time for analysis and archival. The LDN-client also manages the storing of data on the PC-workstation hard disk. The LDN-server software (also an in-house effort) analyses the data from each client and performs event triangulations. Time-of-arrival (TOA) and related hybrid algorithms, lightning-type and event discriminating routines are also implemented in the LDN-server software. We also have developed software to visually monitor lightning events in real-time from all clients and the triangulated events. We are currently monitoring and studying the spatial, temporal, and type distribution of lightning strikes associated with electrical storms and tropical cyclones in the vicinity of Puerto Rico.

Systematically Studying Kinase Inhibitor Induced Signaling Network Signatures by Integrating Both Therapeutic and Side Effects

PubMed Central

Shao, Hongwei; Peng, Tao; Ji, Zhiwei; Su, Jing; Zhou, Xiaobo

2013-01-01

Substantial effort in recent years has been devoted to analyzing data based large-scale biological networks, which provide valuable insight into the topologies of complex biological networks but are rarely context specific and cannot be used to predict the responses of cell signaling proteins to specific ligands or compounds. In this work, we proposed a novel strategy to investigate kinase inhibitor induced pathway signatures by integrating multiplex data in Library of Integrated Network-based Cellular Signatures (LINCS), e.g. KINOMEscan data and cell proliferation/mitosis imaging data. Using this strategy, we first established a PC9 cell line specific pathway model to investigate the pathway signatures in PC9 cell line when perturbed by a small molecule kinase inhibitor GW843682. This specific pathway revealed the role of PI3K/AKT in modulating the cell proliferation process and the absence of two anti-proliferation links, which indicated a potential mechanism of abnormal expansion in PC9 cell number. Incorporating the pathway model for side effects on primary human hepatocytes, it was used to screen 27 kinase inhibitors in LINCS database and PF02341066, known as Crizotinib, was finally suggested with an optimal concentration 4.6 uM to suppress PC9 cancer cell expansion while avoiding severe damage to primary human hepatocytes. Drug combination analysis revealed that the synergistic effect region can be predicted straightforwardly based on a threshold which is an inherent property of each kinase inhibitor. Furthermore, this integration strategy can be easily extended to other specific cell lines to be a powerful tool for drug screen before clinical trials. PMID:24339888

The Study on the Communication Network of Wide Area Measurement System in Electricity Grid

NASA Astrophysics Data System (ADS)

Xiaorong, Cheng; Ying, Wang; Yangdan, Ni

Wide area measurement system(WAMS) is a fundamental part of security defense in Smart Grid, and the communication system of WAMS is an important part of Electric power communication network. For a large regional network is concerned, the real-time data which is transferred in the communication network of WAMS will affect the safe operation of the power grid directly. Therefore, WAMS raised higher requirements for real-time, reliability and security to its communication network. In this paper, the architecture of WASM communication network was studied according to the seven layers model of the open systems interconnection(OSI), and the network architecture was researched from all levels. We explored the media of WAMS communication network, the network communication protocol and network technology. Finally, the delay of the network were analyzed.

Tailoring the visual communication of climate projections for local adaptation practitioners in Germany and the UK.

PubMed

Lorenz, Susanne; Dessai, Suraje; Forster, Piers M; Paavola, Jouni

2015-11-28

Visualizations are widely used in the communication of climate projections. However, their effectiveness has rarely been assessed among their target audience. Given recent calls to increase the usability of climate information through the tailoring of climate projections, it is imperative to assess the effectiveness of different visualizations. This paper explores the complexities of tailoring through an online survey conducted with 162 local adaptation practitioners in Germany and the UK. The survey examined respondents' assessed and perceived comprehension (PC) of visual representations of climate projections as well as preferences for using different visualizations in communicating and planning for a changing climate. Comprehension and use are tested using four different graph formats, which are split into two pairs. Within each pair the information content is the same but is visualized differently. We show that even within a fairly homogeneous user group, such as local adaptation practitioners, there are clear differences in respondents' comprehension of and preference for visualizations. We do not find a consistent association between assessed comprehension and PC or use within the two pairs of visualizations that we analysed. There is, however, a clear link between PC and use of graph format. This suggests that respondents use what they think they understand the best, rather than what they actually understand the best. These findings highlight that audience-specific targeted communication may be more complex and challenging than previously recognized. © 2015 The Authors.

Application of Field System-FS9 and a PC to Antenna Control Unit interface in Radio Astronomy in Peru

NASA Astrophysics Data System (ADS)

Vidal, E. V. S.; Ishitsuka, J. I. I.; Koyama, K. Y.

2006-08-01

We are in the process to transform a 32m antenna in Peru, used for telecommunications, into a Radio Telescope to perform Radio Astronomy in Peru. The 32m antenna of Peru constructed by NEC was used for telecommunications with communications satellites at 6 GHz for transmission, and 4 GHz for reception. In collaboration of National Institute of Information and Communications Technology (NICT) Japan, and National Observatory of Japan we developed an Antenna Control System for the 32m antenna in Peru. It is based on the Field System FS9, software released by NASA for VLBI station, and an interface to link PC within FS9 software (PC-FS9) and Antenna Control Unit (ACU) of the 32 meters antenna. The PC-FS9 controls the antenna, commands are translated by interface into control signals compatibles with the ACU using: an I/O digital card with two 20bits ports to read azimuth and elevation angles, one 16bits port for reading status of ACU, one 24bits port to send pulses to start or stop operations of antenna, two channels are analogic outputs to drive the azimuth and elevation motors of the antenna, a LCD display to show the status of interface and error messages, and one serial port for communications with PC-FS9,. The first experiment of the control system was made with 11m parabolic antenna of Kashima Space Research Center (NICT), where we tested the right working of the routines implemented for de FS9 software, and simulations was made with looped data between output and input of the interface, both test were done successfully. With this scientific instrument we will be able to contribute with researching of astrophysics. We expect to into a near future to work at 6.7GHz to study Methanol masers, and higher frequencies with some improvements of the surface of the dish.

Multiple-Ring Digital Communication Network

NASA Technical Reports Server (NTRS)

Kirkham, Harold

1992-01-01

Optical-fiber digital communication network to support data-acquisition and control functions of electric-power-distribution networks. Optical-fiber links of communication network follow power-distribution routes. Since fiber crosses open power switches, communication network includes multiple interconnected loops with occasional spurs. At each intersection node is needed. Nodes of communication network include power-distribution substations and power-controlling units. In addition to serving data acquisition and control functions, each node acts as repeater, passing on messages to next node(s). Multiple-ring communication network operates on new AbNET protocol and features fiber-optic communication.

A Sensor Middleware for integration of heterogeneous medical devices.

PubMed

Brito, M; Vale, L; Carvalho, P; Henriques, J

2010-01-01

In this paper, the architecture of a modular, service-oriented, Sensor Middleware for data acquisition and processing is presented. The described solution was developed with the purpose of solving two increasingly relevant problems in the context of modern pHealth systems: i) to aggregate a number of heterogeneous, off-the-shelf, devices from which clinical measurements can be acquired and ii) to provide access and integration with an 802.15.4 network of wearable sensors. The modular nature of the Middleware provides the means to easily integrate pre-processing algorithms into processing pipelines, as well as new drivers for adding support for new sensor devices or communication technologies. Tests performed with both real and artificially generated data streams show that the presented solution is suitable for use both in a Windows PC or a Windows Mobile PDA with minimal overhead.

Better than $l/Mflops sustained: a scalable PC-based parallel computer for lattice QCD

NASA Astrophysics Data System (ADS)

Fodor, Zoltán; Katz, Sándor D.; Papp, Gábor

2003-05-01

We study the feasibility of a PC-based parallel computer for medium to large scale lattice QCD simulations. The Eötvös Univ., Inst. Theor. Phys. cluster consists of 137 Intel P4-1.7GHz nodes with 512 MB RDRAM. The 32-bit, single precision sustained performance for dynamical QCD without communication is 1510 Mflops/node with Wilson and 970 Mflops/node with staggered fermions. This gives a total performance of 208 Gflops for Wilson and 133 Gflops for staggered QCD, respectively (for 64-bit applications the performance is approximately halved). The novel feature of our system is its communication architecture. In order to have a scalable, cost-effective machine we use Gigabit Ethernet cards for nearest-neighbor communications in a two-dimensional mesh. This type of communication is cost effective (only 30% of the hardware costs is spent on the communication). According to our benchmark measurements this type of communication results in around 40% communication time fraction for lattices upto 48 3·96 in full QCD simulations. The price/sustained-performance ratio for full QCD is better than l/Mflops for Wilson (and around 1.5/Mflops for staggered) quarks for practically any lattice size, which can fit in our parallel computer. The communication software is freely available upon request for non-profit organizations.

Transparently Interposing User Code at the System Interface

DTIC Science & Technology

1992-09-01

trademarks of Symantec Corporation. AFS is a trademark of Transarc Corporation. PC-cillin is a trademark of Trend Micro Devices, Incorporated. Scribe is a...communication. Finally, both the Norton AntiVirus [Symantec 91b] and PC-cillin [ Trend 90] anti-virus applications intercept destructive file operations made... Trend Micro Devices, Incorporated, 1990. [Tygar & Yee 91] J. D. Tygar, Bennet Yee. Dyad: A System for Using Physically Secure Coprocessors

Software package for performing experiments about the convolutionally encoded Voyager 1 link

NASA Technical Reports Server (NTRS)

Cheng, U.

1989-01-01

A software package enabling engineers to conduct experiments to determine the actual performance of long constraint-length convolutional codes over the Voyager 1 communication link directly from the Jet Propulsion Laboratory (JPL) has been developed. Using this software, engineers are able to enter test data from the Laboratory in Pasadena, California. The software encodes the data and then sends the encoded data to a personal computer (PC) at the Goldstone Deep Space Complex (GDSC) over telephone lines. The encoded data are sent to the transmitter by the PC at GDSC. The received data, after being echoed back by Voyager 1, are first sent to the PC at GDSC, and then are sent back to the PC at the Laboratory over telephone lines for decoding and further analysis. All of these operations are fully integrated and are completely automatic. Engineers can control the entire software system from the Laboratory. The software encoder and the hardware decoder interface were developed for other applications, and have been modified appropriately for integration into the system so that their existence is transparent to the users. This software provides: (1) data entry facilities, (2) communication protocol for telephone links, (3) data displaying facilities, (4) integration with the software encoder and the hardware decoder, and (5) control functions.

The Ecology of Pneumocystis: Perspectives, Personal Recollections, and Future Research Opportunities

PubMed Central

Walzer, Peter D.

2013-01-01

I am honored to receive the second Lifetime Achievement Award by International Workshops on Opportunistic Protists (IWOP) and to give this lecture. My research involves Pneumocystis, an opportunistic pulmonary fungus that is a major cause of pneumonia (“PcP”) in the immunocompromised host. I decided to focus on Pneumocystis ecology here because it has not attracted much interest. Pneumocystis infection is acquired by inhalation, and the cyst stage appears to be the infective form. Several fungal lung infections, such as coccidiomycosis, are not communicable, but occur by inhaling < 5μ spores from environmental sources (buildings, parks), and can be affected by environmental factors. PcP risk factors include environmental constituents (temperature, humidity, SO2, CO) and outdoor activities (camping). Clusters of PcP have occurred, but no environmental source has been found. Pneumocystis is communicable and outbreaks of PcP, especially in renal transplant patients, are an ongoing problem. Recent evidence suggests that most viable Pneumocystis organisms detected in the air are confined to a patient’s room. Further efforts are needed to define the risk of Pneumocystis transmission in healthcare facilities; to develop more robust preventive measures; and to characterize the effects of climatological and air pollutant factors on Pneumocystis transmission in animal models similar to those used for respiratory viruses. PMID:24001365

Photonic crystal materials and their application in biomedicine.

PubMed

Chen, Huadong; Lou, Rong; Chen, Yanxiao; Chen, Lili; Lu, Jingya; Dong, Qianqian

2017-11-01

Photonic crystal (PC) materials exhibit unique structural colors that originate from their intrinsic photonic band gap. Because of their highly ordered structure and distinct optical characteristics, PC-based biomaterials have advantages in the multiplex detection, biomolecular screening and real-time monitoring of biomolecules. In addition, PCs provide good platforms for drug loading and biomolecule modification, which could be applied to biosensors and biological carriers. A number of methods are now available to fabricate PC materials with variable structure colors, which could be applied in biomedicine. Emphasis is given to the description of various applications of PC materials in biomedicine, including drug delivery, biodetection and tumor screening. We believe that this article will promote greater communication among researchers in the fields of chemistry, material science, biology, medicine and pharmacy.

GLOBECOM '89 - IEEE Global Telecommunications Conference and Exhibition, Dallas, TX, Nov. 27-30, 1989, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

The present conference discusses topics in multiwavelength network technology and its applications, advanced digital radio systems in their propagation environment, mobile radio communications, switching programmability, advancements in computer communications, integrated-network management and security, HDTV and image processing in communications, basic exchange communications radio advancements in digital switching, intelligent network evolution, speech coding for telecommunications, and multiple access communications. Also discussed are network designs for quality assurance, recent progress in coherent optical systems, digital radio applications, advanced communications technologies for mobile users, communication software for switching systems, AI and expert systems in network management, intelligent multiplexing nodes, video and image coding, network protocols and performance, system methods in quality and reliability, the design and simulation of lightwave systems, local radio networks, mobile satellite communications systems, fiber networks restoration, packet video networks, human interfaces for future networks, and lightwave networking.

Mission Risk Reduction Regulatory Change Management

NASA Technical Reports Server (NTRS)

Scroggins, Sharon

2007-01-01

NASA Headquarters Environmental Management Division supports NASA's mission to pioneer the future in space exploration, scientific discovery, and aeronautics research by integrating environmental considerations into programs and projects early-on, thereby proactively reducing NASA's exposure to institutional, programmatic and operational risk. As part of this effort, NASA established the Principal Center for Regulatory Risk Analysis and Communication (RRAC PC) as a resource for detecting, analyzing, and communicating environmental regulatory risks to the NASA stakeholder community. The RRAC PC focuses on detecting emerging environmental regulations and other operational change drivers that may pose risks to NASA programs and facilities, and effectively communicating the potential risks. For example, regulatory change may restrict how and where certain activities or operations may be conducted. Regulatory change can also directly affect the ability to use certain materials by mandating a production phase-out or restricting usage applications of certain materials. Regulatory change can result in significant adverse impacts to NASA programs and facilities due to NASA's stringent performance requirements for materials and components related to human-rated space vehicles. Even if a regulation does not directly affect NASA operations, U.S. and international regulations can pose program risks indirectly through requirements levied on manufacturers and vendors of components and materials. For example, manufacturers can change their formulations to comply with new regulatory requirements. Such changes can require time-consuming and costly requalification certification for use in human spaceflight programs. The RRAC PC has implemented a system for proactively managing regulatory change to minimize potential adverse impacts to NASA programs and facilities. This presentation highlights the process utilized by the RRACPC to communicate regulatory change and the associated potential risks within NASA, as well as the process for communicating and cooperating with other government agencies and industry partners, both domestic and international, to ensure mission success.

FPGA implementation of a ZigBee wireless network control interface to transmit biomedical signals

NASA Astrophysics Data System (ADS)

Gómez López, M. A.; Goy, C. B.; Bolognini, P. C.; Herrera, M. C.

2011-12-01

In recent years, cardiac hemodynamic monitors have incorporated new technologies based on wireless sensor networks which can implement different types of communication protocols. More precisely, a digital conductance catheter system recently developed adds a wireless ZigBee module (IEEE 802.15.4 standards) to transmit cardiac signals (ECG, intraventricular pressure and volume) which would allow the physicians to evaluate the patient's cardiac status in a noninvasively way. The aim of this paper is to describe a control interface, implemented in a FPGA device, to manage a ZigBee wireless network. ZigBee technology is used due to its excellent performance including simplicity, low-power consumption, short-range transmission and low cost. FPGA internal memory stores 8-bit signals with which the control interface prepares the information packets. These data were send to the ZigBee END DEVICE module that receives and transmits wirelessly to the external COORDINATOR module. Using an USB port, the COORDINATOR sends the signals to a personal computer for displaying. Each functional block of control interface was assessed by means of temporal diagrams. Three biological signals, organized in packets and converted to RS232 serial protocol, were sucessfully transmitted and displayed in a PC screen. For this purpose, a custom-made graphical software was designed using LabView.

Federal Emergency Management Information System (FEMIS) System Administration Guide for FEMIS Version 1.4.6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arp, J.A.; Bower, J.C.; Burnett, R.A.

The Federal Emergency Management Information System (FEMIS) is an emergency management planning and response tool that was developed by the Pacific Northwest National Laboratory (PNNL) under the direction of the U.S. Army Chemical Biological Defense Command. The FEMIS System Administration Guide provides information necessary for the system administrator to maintain the FEMIS system. The FEMIS system is designed for a single Chemical Stockpile Emergency Preparedness Program (CSEPP) site that has multiple Emergency Operations Centers (EOCs). Each EOC has personal computers (PCs) that emergency planners and operations personnel use to do their jobs. These PCs are corrected via a local areamore » network (LAN) to servers that provide EOC-wide services. Each EOC is interconnected to other EOCs via a Wide Area Network (WAN). Thus, FEMIS is an integrated software product that resides on client/server computer architecture. The main body of FEMIS software, referred to as the FEMIS Application Software, resides on the PC client(s) and is directly accessible to emergency management personnel. The remainder of the FEMIS software, referred to as the FEMIS Support Software, resides on the UNIX server. The Support Software provides the communication data distribution and notification functionality necessary to operate FEMIS in a networked, client/server environment.« less

Federal Emergency Management Information System (FEMIS), Installation Guide for FEMIS 1.4.6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arp, J.A.; Burnett, R.A.; Carter, R.J.

The Federal Emergency Management Information System (FEMIS) is an emergency management planning and response tool that was developed by the Pacific Northwest National Laboratory (PNNL) under the direction of the U.S. Army Chemical Biological Defense Command. The FEMIS System Administration Guide provides information necessary for the system administrator to maintain the FEMIS system. The FEMIS system is designed for a single Chemical Stockpile Emergency Preparedness Program (CSEPP) site that has multiple Emergency Operations Centers (EOCs). Each EOC has personal computers (PCs) that emergency planners and operations personnel use to do their jobs. These PCs are corrected via a local areamore » network (LAN) to servers that provide EOC-wide services. Each EOC is interconnected to other EOCs via a Wide Area Network (WAN). Thus, FEMIS is an integrated software product that resides on client/server computer architecture. The main body of FEMIS software, referred to as the FEMIS Application Software, resides on the PC client(s) and is directly accessible to emergency management personnel. The remainder of the FEMIS software, referred to as the FEMIS Support Software, resides on the UNIX server. The Support Software provides the communication data distribution and notification functionality necessary to operate FEMIS in a networked, client/server environment.« less

Federal Emergency Management Information System (FEMIS) Data Management Guide for FEMIS Version 1.4.6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Angel, L.K.; Bower, J.C.; Burnett, R.A.

1999-06-29

The Federal Emergency Management Information System (FEMIS) is an emergency management planning and response tool that was developed by the Pacific Northwest National Laboratory (PNNL) under the direction of the U.S. Army Chemical Biological Defense Command. The FEMIS System Administration Guide provides information necessary for the system administrator to maintain the FEMIS system. The FEMIS system is designed for a single Chemical Stockpile Emergency Preparedness Program (CSEPP) site that has multiple Emergency Operations Centers (EOCs). Each EOC has personal computers (PCs) that emergency planners and operations personnel use to do their jobs. These PCs are corrected via a local areamore » network (LAN) to servers that provide EOC-wide services. Each EOC is interconnected to other EOCs via a Wide Area Network (WAN). Thus, FEMIS is an integrated software product that resides on client/server computer architecture. The main body of FEMIS software, referred to as the FEMIS Application Software, resides on the PC client(s) and is directly accessible to emergency management personnel. The remainder of the FEMIS software, referred to as the FEMIS Support Software, resides on the UNIX server. The Support Software provides the communication data distribution and notification functionality necessary to operate FEMIS in a networked, client/server environment.« less

Effects of predation and dispersal on bacterial abundance and contaminant biodegradation.

PubMed

Otto, Sally; Harms, Hauke; Wick, Lukas Y

2017-02-01

Research into the biodegradation of soil contaminants has rarely addressed the consequences of predator-prey interactions. Here, we investigated the joint effect of predation and dispersal networks on contaminant degradation by linking spatial abundances of degrader (Pseudomonas fluorescens LP6a) and predator (Bdellovibrio bacteriovorus) bacteria to the degradation of the major soil contaminant phenanthrene (PHE). We used a laboratory microcosm with a PHE passive dosing system and a glass fiber network to facilitate bacterial dispersal. Different predator-to-prey ratios and spatial arrangements of prey and predator inoculation were used to study predation pressure effects on PHE degradation. We observed that predation resulted in (i) enhanced PHE-degradation at low predator counts (PC) compared to controls lacking predation, (ii) reduced PHE-degradation at elevated PC relative to low PC, and (iii) significant effects of the spatial arrangement of prey and predator inoculation on PHE degradation. Our data suggest that predation facilitated by dispersal networks (such as fungal mycelia) may support the build-up of an effective bacterial biomass and, hence, contaminant biodegradation in heterogeneous systems such as soil. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Economic impact of off-line PC viewer for private folder management

NASA Astrophysics Data System (ADS)

Song, Koun-Sik; Shin, Myung J.; Lee, Joo Hee; Auh, Yong H.

1999-07-01

We developed a PC-based clinical workstation and implemented at Asan Medical Center in Seoul, Korea, Hardwares used were Pentium-II, 8M video memory, 64-128 MB RAM, 19 inch color monitor, and 10/100Mbps network adaptor. One of the unique features of this workstation is management tool for folders reside both in PACS short-term storage unit and local hard disk. Users can copy the entire study or part of the study to local hard disk, removable storages, or CD recorder. Even the images in private folders in PACS short-term storage can be copied to local storage devices. All images are saved as DICOM 3.0 file format with 2:1 lossless compression. We compared the prices of copy films and storage medias considering the possible savings of expensive PACS short- term storage and network traffic. Price savings of copy film is most remarkable in MR exam. Price savings arising from minimal use of short-term unit was 50,000 dollars. It as hard to calculate the price savings arising from the network usage. Off-line PC viewer is a cost-effective way of handling private folder management under the PACS environment.

GLOBECOM '86 - Global Telecommunications Conference, Houston, TX, Dec. 1-4, 1986, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

Papers are presented on local area networks; formal methods for communication protocols; computer simulation of communication systems; spread spectrum and coded communications; tropical radio propagation; VLSI for communications; strategies for increasing software productivity; multiple access communications; advanced communication satellite technologies; and spread spectrum systems. Topics discussed include Space Station communication and tracking development and design; transmission networks; modulation; data communications; computer network protocols and performance; and coding and synchronization. Consideration is given to free space optical communications systems; VSAT communication networks; network topology design; advances in adaptive filtering echo cancellation and adaptive equalization; advanced signal processing for satellite communications; the elements, design, and analysis of fiber-optic networks; and advances in digital microwave systems.

Multi/demulti-plexer based on transverse mode conversion in photonic crystal waveguides.

PubMed

Zhou, Wen; Zhuang, Yuyang; Ji, Ke; Chen, He-ming

2015-09-21

A novel mode multiplexer and demultiplexer (MMUX/DEMMUX) based on 2-D photonic crystal (PC) at 1550 nm is proposed. The PC-based mode MMUX/DEMMUX including mode conversion function with a single-mode and multi-mode waveguides can be realized by quasi phase-matching TE(0) & TE(1) modes of two waveguides. 2DFinite-Difference-Time-Domain and beam propagation methods are used for simulation. The results show that PC-based mode MMUX/DEMMUX has the potential for high-capacity MDM optical communication systems with a low insertion loss (<0.36dB), low mode crosstalk (< -20.9 dB) and wide bandwidth (~100 nm).

[A skin cell segregating control system based on PC].

PubMed

Liu, Wen-zhong; Zhou, Ming; Zhang, Hong-bing

2005-11-01

A skin cell segregating control system based on PC (personal computer) is presented in this paper. Its front controller is a single-chip microcomputer which enables the manipulation for 6 patients simultaneously, and thus provides a great convenience for clinical treatments for vitiligo. With the use of serial port communication technology, it's possible to monitor and control the front controller in a PC terminal. And the application of computer image acquisition technology realizes the synchronous acquisition of pathologic shin cell images pre/after the operation and a case history. Clinical tests prove its conformity with national standards and the pre-set technological requirements.

Research on key technology of space laser communication network

NASA Astrophysics Data System (ADS)

Chang, Chengwu; Huang, Huiming; Liu, Hongyang; Gao, Shenghua; Cheng, Liyu

2016-10-01

Since the 21st century, Spatial laser communication has made a breakthrough development. Europe, the United States, Japan and other space powers have carried out the test of spatial laser communication technology on-orbit, and put forward a series of plans. In 2011, China made the first technology demonstration of satellite-ground laser communication carried by HY-2 satellite. Nowadays, in order to improve the transmission rate of spatial network, the topic of spatial laser communication network is becoming a research hotspot at home and abroad. This thesis, from the basic problem of spatial laser communication network to solve, analyzes the main difference between spatial network and ground network, which draws forth the key technology of spatial laser communication backbone network, and systematically introduces our research on aggregation, addressing, architecture of spatial network. From the perspective of technology development status and trends, the thesis proposes the development route of spatial laser communication network in stages. So as to provide reference about the development of spatial laser communication network in China.

Formation of porous networks on polymeric surfaces by femtosecond laser micromachining

NASA Astrophysics Data System (ADS)

Assaf, Youssef; Kietzig, Anne-Marie

2017-02-01

In this study, porous network structures were successfully created on various polymer surfaces by femtosecond laser micromachining. Six different polymers (poly(tetrafluoroethylene) (PTFE), poly(methyl methacrylate) (PMMA), high density poly(ethylene) (HDPE), poly(lactic acid) (PLA), poly(carbonate) (PC), and poly(ethylene terephthalate) (PET)) were machined at different fluences and pulse numbers, and the resulting structures were identified and compared by lacunarity analysis. At low fluence and pulse numbers, porous networks were confirmed to form on all materials except PLA. Furthermore, all networks except for PMMA were shown to bundle up at high fluence and pulse numbers. In the case of PC, a complete breakdown of the structure at such conditions was observed. Operation slightly above threshold fluence and at low pulse numbers is therefore recommended for porous network formation. Finally, the thickness over which these structures formed was measured and compared to two intrinsic material dependent parameters: the single pulse threshold fluence and the incubation coefficient. Results indicate that a lower threshold fluence at operating conditions favors material removal over structure formation and is hence detrimental to porous network formation. Favorable machining conditions and material-dependent parameters for the formation of porous networks on polymer surfaces have thus been identified.

APC-PC Combined Scheme in Gilbert Two State Model: Proposal and Study

NASA Astrophysics Data System (ADS)

Bulo, Yaka; Saring, Yang; Bhunia, Chandan Tilak

2017-04-01

In an automatic repeat request (ARQ) scheme, a packet is retransmitted if it gets corrupted due to transmission errors caused by the channel. However, an erroneous packet may contain both erroneous bits and correct bits and hence it may still contain useful information. The receiver may be able to combine this information from multiple erroneous copies to recover the correct packet. Packet combining (PC) is a simple and elegant scheme of error correction in transmitted packet, in which two received copies are XORed to obtain the bit location of erroneous bits. Thereafter, the packet is corrected by bit inversion of bit located as erroneous. Aggressive packet combining (APC) is a logic extension of PC primarily designed for wireless communication with objective of correcting error with low latency. PC offers higher throughput than APC, but PC does not correct double bit errors if occur in same bit location of erroneous copies of the packet. A hybrid technique is proposed to utilize the advantages of both APC and PC while attempting to remove the limitation of both. In the proposed technique, applications of APC-PC on Gilbert two state model has been studied. The simulation results show that the proposed technique offers better throughput than the conventional APC and lesser packet error rate than PC scheme.

Gel-expanded to gel-condensed transition in neurofilament networks revealed by direct force measurements

NASA Astrophysics Data System (ADS)

Beck, Roy; Deek, Joanna; Jones, Jayna B.; Safinya, Cyrus R.

2010-01-01

Neurofilaments (NF)-the principal cytoskeletal constituent of myelinated axons in vertebrates-consist of three molecular-weight subunit proteins NF-L (low), NF-M (medium) and NF-H (high), assembled to form mature filaments with protruding unstructured C-terminus side arms. Liquid-crystal gel networks of side-arm-mediated neurofilament assemblies have a key role in the mechanical stability of neuronal processes. Disruptions of the neurofilament network, owing to neurofilament over-accumulation or incorrect side-arm interactions, are a hallmark of motor-neuron diseases including amyotrophic lateral sclerosis. Using synchrotron X-ray scattering, we report on a direct measurement of forces in reconstituted neurofilament gels under osmotic pressure (P). With increasing pressure near physiological salt and average phosphorylation conditions, NF-LMH, comprising the three subunits near in vivo composition, or NF-LH gels, undergo for P>Pc~10kPa, an abrupt non-reversible gel-expanded to gel-condensed transition. The transition indicates side-arm-mediated attractions between neurofilaments consistent with an electrostatic model of interpenetrating chains. In contrast, NF-LM gels remain in a collapsed state for PPc. These findings, which delineate the distinct roles of NF-M and NF-H in regulating neurofilament interactions, shed light on possible mechanisms for disruptions of optimal mechanical network properties.

Research and design of intelligent distributed traffic signal light control system based on CAN bus

NASA Astrophysics Data System (ADS)

Chen, Yu

2007-12-01

Intelligent distributed traffic signal light control system was designed based on technologies of infrared, CAN bus, single chip microprocessor (SCM), etc. The traffic flow signal is processed with the core of SCM AT89C51. At the same time, the SCM controls the CAN bus controller SJA1000/transceiver PCA82C250 to build a CAN bus communication system to transmit data. Moreover, up PC realizes to connect and communicate with SCM through USBCAN chip PDIUSBD12. The distributed traffic signal light control system with three control styles of Vehicle flux, remote and PC is designed. This paper introduces the system composition method and parts of hardware/software design in detail.

Wireless Augmented Reality Communication System

NASA Technical Reports Server (NTRS)

Agan, Martin (Inventor); Devereaux, Ann (Inventor); Jedrey, Thomas (Inventor)

2015-01-01

A portable unit is for video communication to select a user name in a user name network. A transceiver wirelessly accesses a communication network through a wireless connection to a general purpose node coupled to the communication network. A user interface can receive user input to log on to a user name network through the communication network. The user name network has a plurality of user names, at least one of the plurality of user names is associated with a remote portable unit, logged on to the user name network and available for video communication.

Wireless Augmented Reality Communication System

NASA Technical Reports Server (NTRS)

Jedrey, Thomas (Inventor); Agan, Martin (Inventor); Devereaux, Ann (Inventor)

2017-01-01

A portable unit is for video communication to select a user name in a user name network. A transceiver wirelessly accesses a communication network through a wireless connection to a general purpose node coupled to the communication network. A user interface can receive user input to log on to a user name network through the communication network. The user name network has a plurality of user names, at least one of the plurality of user names is associated with a remote portable unit, logged on to the user name network and available for video communication.

Exploring Education and Training Needs in Palliative Care among Family Physicians in Mumbai: A Qualitative Study.

PubMed

Damani, Anuja; Ghoshal, Arunangshu; Dighe, Manjiri; Dhiliwal, Sunil; Muckaden, Maryann

2018-01-01

Patients with chronic life-limiting conditions on palliative care (PC) prefer to be treated at home. Medical care by family physicians (FPs) reduces demand on costly and busy hospital facilities. Working of PC team in collaboration with FPs is thus helpful in home-based management of patients. This study aimed at exploring the extent of knowledge of FPs about PC and the need for additional training. Semi-structured interviews were conducted with ten FPs from two suburbs of Mumbai, currently served by home care services of a tertiary cancer care center. Data were digitally recorded, transcribed, and analyzed using exploratory analysis followed by content analysis to develop thematic codes. FPs perceive PC as symptom control and psychological support helpful in managing patients with advanced life-limiting illnesses. Further training would help them in PC provision. Such training programs should preferably focus on symptom management and communication skills. There is a need for further research in designing a training module for FPs to get better understanding of the principles of PC.

Exploring Education and Training Needs in Palliative Care among Family Physicians in Mumbai: A Qualitative Study

PubMed Central

Damani, Anuja; Ghoshal, Arunangshu; Dighe, Manjiri; Dhiliwal, Sunil; Muckaden, Maryann

2018-01-01

Context: Patients with chronic life-limiting conditions on palliative care (PC) prefer to be treated at home. Medical care by family physicians (FPs) reduces demand on costly and busy hospital facilities. Working of PC team in collaboration with FPs is thus helpful in home-based management of patients. Aims: This study aimed at exploring the extent of knowledge of FPs about PC and the need for additional training. Settings and Design: Semi-structured interviews were conducted with ten FPs from two suburbs of Mumbai, currently served by home care services of a tertiary cancer care center. Subjects and Methods: Data were digitally recorded, transcribed, and analyzed using exploratory analysis followed by content analysis to develop thematic codes. Results and Conclusions: FPs perceive PC as symptom control and psychological support helpful in managing patients with advanced life-limiting illnesses. Further training would help them in PC provision. Such training programs should preferably focus on symptom management and communication skills. There is a need for further research in designing a training module for FPs to get better understanding of the principles of PC. PMID:29736114

A Computer Spreadsheet for Locating Assistive Devices.

ERIC Educational Resources Information Center

Palmer, Catherine V.; Garstecki, Dean C.

1988-01-01

The article presents a directory of assistive devices for persons with hearing impairments in a grid format by distributor and type of device (alerting devices, telephone, TV/radio/stereo, personal communication, group communication, and other). The product locator is also available in spreadsheet form for either the Macintosh or IBM-PC computers.…

An all-silicon optical PC-to-PC link utilizing USB

NASA Astrophysics Data System (ADS)

Goosen, Marius E.; Alberts, Antonie C.; Venter, Petrus J.; du Plessis, Monuko; Rademeyer, Pieter

2013-02-01

An integrated silicon light source still remains the Holy Grail for integrated optical communication systems. Hot carrier luminescent light sources provide a way to create light in a standard CMOS process, potentially enabling cost effective optical communication between CMOS integrated circuits. In this paper we present a 1 Mb/s integrated silicon optical link for information transfer, targeting a real-world integrated solution by connecting two PCs via a USB port while transferring data optically between the devices. This realization represents the first optical communication product prototype utilizing a CMOS light emitter. The silicon light sources which are implemented in a standard 0.35 μm CMOS technology are electrically modulated and detected using a commercial silicon avalanche photodiode. Data rates exceeding 10 Mb/s using silicon light sources have previously been demonstrated using raw bit streams. In this work data is sent in two half duplex streams accompanied with the separate transmission of a clock. Such an optical communication system could find application in high noise environments where data fidelity, range and cost are a determining factor.

NASA's Agency-Wide Strategy for Environmental Regulatory Risk Analysis and Communication

NASA Technical Reports Server (NTRS)

Scroggins, Sharon

2008-01-01

NASA's Agency-wide.resource for identifying and managing risks associated with changing environmental regulations Goals of the RRAC PC: 1) Proactively. detect, analyze and communicate environmental regulatory risks to NASA Programs and facilities; 2) Communicate with regulators and participate in the mitigation of such risks; and 3) Provide centralized support on emerging regulations to NASA HQ Environmental Management Division. When significant regulatory changes are identified, timely communication is essential. Communication of changing requirements to the regulatory stakeholders - NASA Programs and Facilities. Communication of potential issues to management and, when appropriate, back to the regulating agency.

A scalable PC-based parallel computer for lattice QCD

NASA Astrophysics Data System (ADS)

Fodor, Z.; Katz, S. D.; Pappa, G.

2003-05-01

A PC-based parallel computer for medium/large scale lattice QCD simulations is suggested. The Eo¨tvo¨s Univ., Inst. Theor. Phys. cluster consists of 137 Intel P4-1.7GHz nodes. Gigabit Ethernet cards are used for nearest neighbor communication in a two-dimensional mesh. The sustained performance for dynamical staggered (wilson) quarks on large lattices is around 70(110) GFlops. The exceptional price/performance ratio is below $1/Mflop.

Phthalocyanine based metal containing porous carbon sheet

NASA Astrophysics Data System (ADS)

Honda, Z.; Sakaguchi, Y.; Tashiro, M.; Hagiwara, M.; Kida, T.; Sakai, M.; Fukuda, T.; Kamata, N.

2017-03-01

Highly-ordered fused-ring poly copper phthalocyanine (PCuPc) was prepared using copper octacyanophthalocyanine as a building block, and two-dimensional (2D) square superlattices were directly observed by the transmission electron microscopy. Remarkably, we have found a formation of polymer network that consists of a 2D porous PCuPc sheet in which the centers of phthalocyanine units are alternately occupied by Cu atom and vacancy. Using this "half-filling" PCuPc, it must be possible to create alternating arrangements for transition metal centers, and therefore control the magnetic properties of the 2D carbon sheets.

The effects of IL-1β, IL-8, G-CSF and TNF-α as molecular adjuvant on the immune response to an E. tarda subunit vaccine in flounder (Paralichthys olivaceus).

PubMed

Guo, Ming; Tang, Xiaoqian; Sheng, Xiuzhen; Xing, Jing; Zhan, Wenbin

2018-06-01

Cytokines play vital roles in mounting immune responses and activating host defense network. In this study, the expression plasmid pcDNA3.1 (pcN3) encoding four flounder (Paralichthys olivaceus) cytokines including IL-1β, TNF-α, IL-8 or G-CSF (pcIL-1β, pcTNF-α, pcIL-8 and pcG-CSF) were successfully constructed, and their adjuvant potential on an Edwardsiella tarda (E. tarda) subunit vaccine OmpV (rOmpV) were comparatively analyzed in vaccinated flounder model. Results revealed that flounder vaccinated with rOmpV plus pcIL-1β, pcIL-8 or pcG-CSF produced the relative percent survivals (RPS) of 71%, 65% and 49% respectively, which were higher than that in flounder vaccinated with rOmpV plus pcTNF-α (39%) or pcN3 (36%, the control group). Immunological analysis showed that: (1) except pcTNF-α, higher levels of anti-E. tarda serum antibodies and sIg + lymphocytes in spleen, head kidney and peripheral blood were significantly enhanced by pcIL-1β, pcIL-8 or pcG-CSF, however, pcIL-8 and pcIL-1β enhanced higher levels of sIg + lymphocytes and anti-E. tarda antibodies than pcG-CSF; (2) pcTNF-α could promote the up-regulation of genes participated in cellular immunity (MHCIα, IFN-γ, CD8α and CD8β), pcIL-1β could enhance the expression of genes related to humoral immunity (CD4-1, CD4-2, MHCIIα and IgM), and all the detected genes were augmented by pcIL-8 and pcG-CSF; Among the four cytokines, pcIL-8 and pcIL-1β could strengthen the highest levels of genes participated in cellular immunity and humoral immunity, respectively. These results demonstrated that pcIL-8 and pcIL-1β could enhance stronger cellular and/or humoral immunity induced by rOmpV than pcG-CSF and pcTNF-α, and evoked higher RPS against E. tarda challenge in flounder, which indicated that pcIL-8 and pcIL-1β are promising adjuvants of vaccines in controlling E. tarda infection. Copyright © 2018 Elsevier Ltd. All rights reserved.

Targeted agents for patients with advanced/metastatic pancreatic cancer: A protocol for systematic review and network meta-analysis.

PubMed

Di, Baoshan; Pan, Bei; Ge, Long; Ma, Jichun; Wu, Yiting; Guo, Tiankang

2018-03-01

Pancreatic cancer (PC) is a devastating malignant tumor. Although surgical resection may offer a good prognosis and prolong survival, approximately 80% patients with PC are always diagnosed as unresectable tumor. National Comprehensive Cancer Network's (NCCN) recommended gemcitabine-based chemotherapy as efficient treatment. While, according to recent studies, targeted agents might be a better available option for advanced or metastatic pancreatic cancer patients. The aim of this systematic review and network meta-analysis will be to examine the differences of different targeted interventions for advanced/metastatic PC patients. We will conduct this systematic review and network meta-analysis using Bayesian method and according to Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P) statement. To identify relevant studies, 6 electronic databases including PubMed, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), Web of science, CNKI (Chinese National Knowledge Infrastructure), and CBM (Chinese Biological Medical Database) will be searched. The risk of bias in included randomized controlled trials (RCTs) will be assessed using the Cochrane Handbook version 5.1.0. And we will use GRADE approach to assess the quality of evidence from network meta-analysis. Data will be analyzed using R 3.4.1 software. To the best of our knowledge, this systematic review and network meta-analysis will firstly use both direct and indirect evidence to compare the differences of different targeted agents and targeted agents plus chemotherapy for advanced/metastatic pancreatic cancer patients. This is a protocol of systematic review and meta-analysis, so the ethical approval and patient consent are not required. We will disseminate the results of this review by submitting to a peer-reviewed journal.

[What are hospitals and primary care doing to mitigate the social impact of serious adverse events].

PubMed

Mira, José Joaquín; Carrillo, Irene; Lorenzo, Susana

To explore what hospitals and primary care (PC) are doing to reduce the negative social impact of a serious adverse event (AE). We surveyed 195 hospital (n=113) and PC (n=82) managers from eight autonomous communities to explore the level of implementation of five interventions recommended after an AE to protect the reputation of healthcare institutions. Most institutions (70, 45.2% PC, and 85, 54.8% hospitals) did not have a crisis plan to protect their reputation after an AE. Internal (p=0.0001) and external (p=0.012) communications were addressed better in PC than in hospitals. Very few institutions had defined the managers' role in case of an AE (10.7% hospitals versus 6.25% PC). A majority of healthcare institutions have not planned crisis intervention after an AE with severe consequences nor have they defined plans to recover citizens' trust after an AE. Copyright © 2016 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

Implementation and assessment of a fast-track programme to improve communication between primary and specialized care in patients with suspected cancer: how to shorten time between initial symptoms of cancer, diagnosis and initiation of treatment.

PubMed

Martínez, M T; González, I; Tarazona, N; Roselló, S; Saiz, R; Sanmartín, A; Martínez-Agulló, Á; Caballero, A; Mas, P; Franco, J; Martínez-Jabaloyas, J; García-Callejo, J; Martín, V; Navarro, J; Teruel, A; Lluch, A; Chirivella, I

2015-02-01

This study aims to asses a cancer fast-track programme (CFP) to shorten the time since a patient with suspicion of cancer is referred by the primary care (PC) physician to the specialized medical team. Guidelines for main suspected tumours were designed to help PC physicians to detect and rapidly refer cases to the CFP oncology coordinator, who sent them to the appropriate department to accelerate diagnosis, staging and therapy. All patients analysed in this report were referred from June 2009 to July 2012. A total of 897 suspected cancer cases were submitted and finally 705 were studied. In 205 (29 %) a cancer diagnosis was confirmed within 23 days (median). Therapy was initiated within 46 days after referral (median). Early diagnoses with a potential curative approach were made in 166 (82 %). This CFP decreased the waiting time for cancer diagnosis, by improving communication between PC physician and specialized care teams. Most patients included in this program could get therapy with curative intent.

Two-dimensional plasmons in the random impedance network model of disordered thin film nanocomposites

NASA Astrophysics Data System (ADS)

Olekhno, N. A.; Beltukov, Y. M.

2018-05-01

Random impedance networks are widely used as a model to describe plasmon resonances in disordered metal-dielectric nanocomposites. Two-dimensional networks are applied when considering thin films despite the fact that such networks correspond to the two-dimensional electrodynamics [Clerc et al., J. Phys. A 29, 4781 (1996), 10.1088/0305-4470/29/16/006]. In the present work, we propose a model of two-dimensional systems with the three-dimensional Coulomb interaction and show that this model is equivalent to the planar network with long-range capacitive links between distant sites. In the case of a metallic film, we obtain the well-known dispersion of two-dimensional plasmons ω ∝√{k } . We study the evolution of resonances with a decrease in the metal filling factor within the framework of the proposed model. In the subcritical region with the metal filling p lower than the percolation threshold pc, we observe a gap with Lifshitz tails in the spectral density of states (DOS). In the supercritical region p >pc , the DOS demonstrates a crossover between plane-wave two-dimensional plasmons and resonances of finite clusters.

Offline Social Relationships and Online Cancer Communication: Effects of Social and Family Support on Online Social Network Building.

PubMed

Namkoong, Kang; Shah, Dhavan V; Gustafson, David H

2017-11-01

This study investigates how social support and family relationship perceptions influence breast cancer patients' online communication networks in a computer-mediated social support (CMSS) group. To examine social interactions in the CMSS group, we identified two types of online social networks: open and targeted communication networks. The open communication network reflects group communication behaviors (i.e., one-to-many or "broadcast" communication) in which the intended audience is not specified; in contrast, the targeted communication network reflects interpersonal discourses (i.e., one-to-one or directed communication) in which the audience for the message is specified. The communication networks were constructed by tracking CMSS group usage data of 237 breast cancer patients who participated in one of two National Cancer Institute-funded randomized clinical trials. Eligible subjects were within 2 months of a diagnosis of primary breast cancer or recurrence at the time of recruitment. Findings reveal that breast cancer patients who perceived less availability of offline social support had a larger social network size in the open communication network. In contrast, those who perceived less family cohesion had a larger targeted communication network in the CMSS group, meaning they were inclined to use the CMSS group for developing interpersonal relationships.

Pilot Evaluation of a Palliative and End-of-Life Communication Intervention for Parents of Children With a Brain Tumor.

PubMed

Hendricks-Ferguson, Verna L; Pradhan, Kamnesh; Shih, Chie-Schin; Gauvain, Karen M; Kane, Javier R; Liu, Jingxia; Haase, Joan E

Providing timely palliative and end-of-life care (PC/EOL) information to parents of children with a serious illness is a national health care priority. The goals of this study were to determine feasibility, acceptability, and parent responses related to a PC/EOL communication intervention, titled "Communication Plan: Early through End of Life (COMPLETE)" to parents of children with a brain tumor. The study was a 2-site prospective, single-group pilot study targeting parents' stress and coping outcomes. The sample included 13 parents of 11 children (ie, 11 families). During the first 6 months postdiagnosis, we evaluated parent outcomes at 4 time points (baseline and 3 post-sessions). Our findings included significant decline in decision regret ( P = .0089); strong, significantly increased hope ( P ≤ .0001); and significantly decreased uncertainty ( P = .04). Over time, more than half of the parents (61.5%) preferred to receive information about their child's current condition and PC/EOL options. Our findings provide evidence to suggest that the COMPLETE intervention is feasible and acceptable and produces promising effects on 3 parent outcomes (ie, decision regret, hope, and uncertainty) in parents of children with a brain tumor. Further research is indicated to evaluate COMPLETE with a larger sample of parents of children with cancer and with a control group.

Inferring functional connectivity in MRI using Bayesian network structure learning with a modified PC algorithm

PubMed Central

Iyer, Swathi; Shafran, Izhak; Grayson, David; Gates, Kathleen; Nigg, Joel; Fair, Damien

2013-01-01

Resting state functional connectivity MRI (rs-fcMRI) is a popular technique used to gauge the functional relatedness between regions in the brain for typical and special populations. Most of the work to date determines this relationship by using Pearson's correlation on BOLD fMRI timeseries. However, it has been recognized that there are at least two key limitations to this method. First, it is not possible to resolve the direct and indirect connections/influences. Second, the direction of information flow between the regions cannot be differentiated. In the current paper, we follow-up on recent work by Smith et al (2011), and apply a Bayesian approach called the PC algorithm to both simulated data and empirical data to determine whether these two factors can be discerned with group average, as opposed to single subject, functional connectivity data. When applied on simulated individual subjects, the algorithm performs well determining indirect and direct connection but fails in determining directionality. However, when applied at group level, PC algorithm gives strong results for both indirect and direct connections and the direction of information flow. Applying the algorithm on empirical data, using a diffusion-weighted imaging (DWI) structural connectivity matrix as the baseline, the PC algorithm outperformed the direct correlations. We conclude that, under certain conditions, the PC algorithm leads to an improved estimate of brain network structure compared to the traditional connectivity analysis based on correlations. PMID:23501054

Internet and Intranet Use with a PC: Effects of Adapter Cards, Windows Versions and TCP/IP Software on Networking Performance.

ERIC Educational Resources Information Center

Nieuwenhuysen, Paul

1997-01-01

Explores data transfer speeds obtained with various combinations of hardware and software components through a study of access to the Internet from a notebook computer connected to a local area network based on Ethernet and TCP/IP (transmission control protocol/Internet protocol) network protocols. Upgrading is recommended for higher transfer…

ICC '86; Proceedings of the International Conference on Communications, Toronto, Canada, June 22-25, 1986, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

Papers are presented on ISDN, mobile radio systems and techniques for digital connectivity, centralized and distributed algorithms in computer networks, communications networks, quality assurance and impact on cost, adaptive filters in communications, the spread spectrum, signal processing, video communication techniques, and digital satellite services. Topics discussed include performance evaluation issues for integrated protocols, packet network operations, the computer network theory and multiple-access, microwave single sideband systems, switching architectures, fiber optic systems, wireless local communications, modulation, coding, and synchronization, remote switching, software quality, transmission, and expert systems in network operations. Consideration is given to wide area networks, image and speech processing, office communications application protocols, multimedia systems, customer-controlled network operations, digital radio systems, channel modeling and signal processing in digital communications, earth station/on-board modems, computer communications system performance evaluation, source encoding, compression, and quantization, and adaptive communications systems.

A comparison between digital images viewed on a picture archiving and communication system diagnostic workstation and on a PC-based remote viewing system by emergency physicians.

PubMed

Parasyn, A; Hanson, R M; Peat, J K; De Silva, M

1998-02-01

Picture Archiving and Communication Systems (PACS) make possible the viewing of radiographic images on computer workstations located where clinical care is delivered. By the nature of their work this feature is particularly useful for emergency physicians who view radiographic studies for information and use them to explain results to patients and their families. However, the high cost of PACS diagnostic workstations with fuller functionality places limits on the number of and therefore the accessibility to workstations in the emergency department. This study was undertaken to establish how well less expensive personal computer-based workstations would work to support these needs of emergency physicians. The study compared the outcome of observations by 5 emergency physicians on a series of radiographic studies containing subtle abnormalities displayed on both a PACS diagnostic workstation and on a PC-based workstation. The 73 digitized radiographic studies were randomly arranged on both types of workstation over four separate viewing sessions for each emergency physician. There was no statistical difference between a PACS diagnostic workstation and a PC-based workstation in this trial. The mean correct ratings were 59% on the PACS diagnostic workstations and 61% on the PC-based workstations. These findings also emphasize the need for prompt reporting by a radiologist.

The influence of scale structure and sex on parental reports of children’s social (pragmatic) communication symptoms

PubMed Central

Ash, Andrea C.; Redmond, Sean M.; Timler, Geralyn R.; Kean, Jacob

2017-01-01

The addition of social (pragmatic) communication disorder [S(P)CD] to the DSM-5 taxonomy has left clinicians and researchers searching for appropriate diagnostic measures. Factor analysis procedures examined the extent to which S(P)CD symptoms presented within the Children’s Communication Checklist-Second Edition (CCC-2) represented a unique construct and whether these factors were influenced by children’s sex. Parents of 208 children (males = 125 and females = 83) from a community-based sample completed the CCC-2. Two pragmatic scores from the CCC-2 were analysed as follows: the social interaction difference index (SIDI) and a pragmatic composite from the original CCC (PC-5). Factor analysis failed to find a unique factor structure for either pragmatic composite. Analyses uncovered different factor structures for the CCC-2 SIDI and PC-5 composites and for boys and girls. S(P)CD represents a complex combination of symptoms that are poorly differentiated from other language and socioemotional behavioural difficulties. PMID:27936954

Home media server content management

NASA Astrophysics Data System (ADS)

Tokmakoff, Andrew A.; van Vliet, Harry

2001-07-01

With the advent of set-top boxes, the convergence of TV (broadcasting) and PC (Internet) is set to enter the home environment. Currently, a great deal of activity is occurring in developing standards (TV-Anytime Forum) and devices (TiVo) for local storage on Home Media Servers (HMS). These devices lie at the heart of convergence of the triad: communications/networks - content/media - computing/software. Besides massive storage capacity and being a communications 'gateway', the home media server is characterised by the ability to handle metadata and software that provides an easy to use on-screen interface and intelligent search/content handling facilities. In this paper, we describe a research prototype HMS that is being developed within the GigaCE project at the Telematica Instituut . Our prototype demonstrates advanced search and retrieval (video browsing), adaptive user profiling and an innovative 3D component of the Electronic Program Guide (EPG) which represents online presence. We discuss the use of MPEG-7 for representing metadata, the use of MPEG-21 working draft standards for content identification, description and rights expression, and the use of HMS peer-to-peer content distribution approaches. Finally, we outline explorative user behaviour experiments that aim to investigate the effectiveness of the prototype HMS during development.

Motion camera based on a custom vision sensor and an FPGA architecture

NASA Astrophysics Data System (ADS)

Arias-Estrada, Miguel

1998-09-01

A digital camera for custom focal plane arrays was developed. The camera allows the test and development of analog or mixed-mode arrays for focal plane processing. The camera is used with a custom sensor for motion detection to implement a motion computation system. The custom focal plane sensor detects moving edges at the pixel level using analog VLSI techniques. The sensor communicates motion events using the event-address protocol associated to a temporal reference. In a second stage, a coprocessing architecture based on a field programmable gate array (FPGA) computes the time-of-travel between adjacent pixels. The FPGA allows rapid prototyping and flexible architecture development. Furthermore, the FPGA interfaces the sensor to a compact PC computer which is used for high level control and data communication to the local network. The camera could be used in applications such as self-guided vehicles, mobile robotics and smart surveillance systems. The programmability of the FPGA allows the exploration of further signal processing like spatial edge detection or image segmentation tasks. The article details the motion algorithm, the sensor architecture, the use of the event- address protocol for velocity vector computation and the FPGA architecture used in the motion camera system.

Research of the self-healing technologies in the optical communication network of distribution automation

NASA Astrophysics Data System (ADS)

Wang, Hao; Zhong, Guoxin

2018-03-01

Optical communication network is the mainstream technique of the communication networks for distribution automation, and self-healing technologies can improve the in reliability of the optical communication networks significantly. This paper discussed the technical characteristics and application scenarios of several network self-healing technologies in the access layer, the backbone layer and the core layer of the optical communication networks for distribution automation. On the base of the contrastive analysis, this paper gives an application suggestion of these self-healing technologies.

UltraNet Target Parameters. Chapter 1

NASA Technical Reports Server (NTRS)

Kislitzin, Katherine T.; Blaylock, Bruce T. (Technical Monitor)

1992-01-01

The UltraNet is a high speed network capable of rates up to one gigabit per second. It is a hub based network with four optical fiber links connecting each hub. Each link can carry up to 256 megabits of data, and the hub backplane is capable of one gigabit aggregate throughput. Host connections to the hub may be fiber, coax, or channel based. Bus based machines have adapter boards that connect to transceivers in the hub, while channel based machines use a personality module in the hub. One way that the UltraNet achieves its high transfer rates is by off-loading the protocol processing from the hosts to special purpose protocol engines in the UltraNet hubs. In addition, every hub has a PC connected to it by StarLAN for network management purposes. Although there is hub resident and PC resident UltraNet software, this document treats only the host resident UltraNet software.

Finding friends online: online activities by deaf students and their well-being.

PubMed

Blom, Helen; Marschark, Marc; Vervloed, Mathijs P J; Knoors, Harry

2014-01-01

Generally, deaf and hard of hearing (D/HH) children have fewer friends than hearing peers and their friendships are of a lower quality. The research hypothesis was that using the computer to communicate with new online friends through social network sites or playing games with offline friends is associated with D/HH friendship qualities, because it removes certain communication barriers D/HH face in offline communication settings. With online questionnaires the relation between computer use and online, mixed (offline friend who you also speak in online settings), and offline friendship quality of D/HH and hearing students (18-25 years) was compared in both the Netherlands (n = 100) and the United States (n = 122). In addition, the study examined whether the different friendship qualities were related to the participants' well-being. Results showed that, in general, D/HH students' friendship qualities and levels of well-being were similar to their hearing peers. The quality of the mixed friendships was positively related to well-being. Furthermore, the frequency of pc use with both online and offline friends was positively related to friendships qualities in both hearing and D/HH students. A combination of the online and offline friendship seems to be the most important friendship type for both hearing and D/HH students and it is worthwhile to encourage this friendship type.

Secure Control Systems for the Energy Sector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Rhett; Campbell, Jack; Hadley, Mark

2012-03-31

Schweitzer Engineering Laboratories (SEL) will conduct the Hallmark Project to address the need to reduce the risk of energy disruptions because of cyber incidents on control systems. The goals is to develop solutions that can be both applied to existing control systems and designed into new control systems to add the security measures needed to mitigate energy network vulnerabilities. The scope of the Hallmark Project contains four primary elements: 1. Technology transfer of the Secure Supervisory Control and Data Acquisition (SCADA) Communications Protocol (SSCP) from Pacific Northwest National Laboratories (PNNL) to Schweitzer Engineering Laboratories (SEL). The project shall use thismore » technology to develop a Federal Information Processing Standard (FIPS) 140-2 compliant original equipment manufacturer (OEM) module to be called a Cryptographic Daughter Card (CDC) with the ability to directly connect to any PC enabling that computer to securely communicate across serial to field devices. Validate the OEM capabilities with another vendor. 2. Development of a Link Authenticator Module (LAM) using the FIPS 140-2 validated Secure SCADA Communications Protocol (SSCP) CDC module with a central management software kit. 3. Validation of the CDC and Link Authenticator modules via laboratory and field tests. 4. Creation of documents that record the impact of the Link Authenticator to the operators of control systems and on the control system itself. The information in the documents can assist others with technology deployment and maintenance.« less

Finding Friends Online: Online Activities by Deaf Students and Their Well-Being

PubMed Central

Blom, Helen; Marschark, Marc; Vervloed, Mathijs P. J.; Knoors, Harry

2014-01-01

Generally, deaf and hard of hearing (D/HH) children have fewer friends than hearing peers and their friendships are of a lower quality. The research hypothesis was that using the computer to communicate with new online friends through social network sites or playing games with offline friends is associated with D/HH friendship qualities, because it removes certain communication barriers D/HH face in offline communication settings. With online questionnaires the relation between computer use and online, mixed (offline friend who you also speak in online settings), and offline friendship quality of D/HH and hearing students (18–25 years) was compared in both the Netherlands (n = 100) and the United States (n = 122). In addition, the study examined whether the different friendship qualities were related to the participants' well-being. Results showed that, in general, D/HH students' friendship qualities and levels of well-being were similar to their hearing peers. The quality of the mixed friendships was positively related to well-being. Furthermore, the frequency of pc use with both online and offline friends was positively related to friendships qualities in both hearing and D/HH students. A combination of the online and offline friendship seems to be the most important friendship type for both hearing and D/HH students and it is worthwhile to encourage this friendship type. PMID:24520373

Genetic algorithm applied to the selection of factors in principal component-artificial neural networks: application to QSAR study of calcium channel antagonist activity of 1,4-dihydropyridines (nifedipine analogous).

PubMed

Hemmateenejad, Bahram; Akhond, Morteza; Miri, Ramin; Shamsipur, Mojtaba

2003-01-01

A QSAR algorithm, principal component-genetic algorithm-artificial neural network (PC-GA-ANN), has been applied to a set of newly synthesized calcium channel blockers, which are of special interest because of their role in cardiac diseases. A data set of 124 1,4-dihydropyridines bearing different ester substituents at the C-3 and C-5 positions of the dihydropyridine ring and nitroimidazolyl, phenylimidazolyl, and methylsulfonylimidazolyl groups at the C-4 position with known Ca(2+) channel binding affinities was employed in this study. Ten different sets of descriptors (837 descriptors) were calculated for each molecule. The principal component analysis was used to compress the descriptor groups into principal components. The most significant descriptors of each set were selected and used as input for the ANN. The genetic algorithm (GA) was used for the selection of the best set of extracted principal components. A feed forward artificial neural network with a back-propagation of error algorithm was used to process the nonlinear relationship between the selected principal components and biological activity of the dihydropyridines. A comparison between PC-GA-ANN and routine PC-ANN shows that the first model yields better prediction ability.

Making tomorrow's mistakes today: Evolutionary prototyping for risk reduction and shorter development time

NASA Astrophysics Data System (ADS)

Friedman, Gary; Schwuttke, Ursula M.; Burliegh, Scott; Chow, Sanguan; Parlier, Randy; Lee, Lorrine; Castro, Henry; Gersbach, Jim

1993-03-01

In the early days of JPL's solar system exploration, each spacecraft mission required its own dedicated data system with all software applications written in the mainframe's native assembly language. Although these early telemetry processing systems were a triumph of engineering in their day, since that time the computer industry has advanced to the point where it is now advantageous to replace these systems with more modern technology. The Space Flight Operations Center (SFOC) Prototype group was established in 1985 as a workstation and software laboratory. The charter of the lab was to determine if it was possible to construct a multimission telemetry processing system using commercial, off-the-shelf computers that communicated via networks. The staff of the lab mirrored that of a typical skunk works operation -- a small, multi-disciplinary team with a great deal of autonomy that could get complex tasks done quickly. In an effort to determine which approaches would be useful, the prototype group experimented with all types of operating systems, inter-process communication mechanisms, network protocols, packet size parameters. Out of that pioneering work came the confidence that a multi-mission telemetry processing system could be built using high-level languages running in a heterogeneous, networked workstation environment. Experience revealed that the operating systems on all nodes should be similar (i.e., all VMS or all PC-DOS or all UNIX), and that a unique Data Transport Subsystem tool needed to be built to address the incompatibilities of network standards, byte ordering, and socket buffering. The advantages of building a telemetry processing system based on emerging industry standards were numerous: by employing these standards, we would no longer be locked into a single vendor. When new technology came to market which offered ten times the performance at one eighth the cost, it would be possible to attach the new machine to the network, re-compile the application code, and run. In addition, we would no longer be plagued with lack of manufacturer support when we encountered obscure bugs. And maybe, hopefully, the eternal elusive goal of software portability across different vendors' platforms would finally be available. Some highlights of our prototyping efforts are described.

Making tomorrow's mistakes today: Evolutionary prototyping for risk reduction and shorter development time

NASA Technical Reports Server (NTRS)

Friedman, Gary; Schwuttke, Ursula M.; Burliegh, Scott; Chow, Sanguan; Parlier, Randy; Lee, Lorrine; Castro, Henry; Gersbach, Jim

1993-01-01

In the early days of JPL's solar system exploration, each spacecraft mission required its own dedicated data system with all software applications written in the mainframe's native assembly language. Although these early telemetry processing systems were a triumph of engineering in their day, since that time the computer industry has advanced to the point where it is now advantageous to replace these systems with more modern technology. The Space Flight Operations Center (SFOC) Prototype group was established in 1985 as a workstation and software laboratory. The charter of the lab was to determine if it was possible to construct a multimission telemetry processing system using commercial, off-the-shelf computers that communicated via networks. The staff of the lab mirrored that of a typical skunk works operation -- a small, multi-disciplinary team with a great deal of autonomy that could get complex tasks done quickly. In an effort to determine which approaches would be useful, the prototype group experimented with all types of operating systems, inter-process communication mechanisms, network protocols, packet size parameters. Out of that pioneering work came the confidence that a multi-mission telemetry processing system could be built using high-level languages running in a heterogeneous, networked workstation environment. Experience revealed that the operating systems on all nodes should be similar (i.e., all VMS or all PC-DOS or all UNIX), and that a unique Data Transport Subsystem tool needed to be built to address the incompatibilities of network standards, byte ordering, and socket buffering. The advantages of building a telemetry processing system based on emerging industry standards were numerous: by employing these standards, we would no longer be locked into a single vendor. When new technology came to market which offered ten times the performance at one eighth the cost, it would be possible to attach the new machine to the network, re-compile the application code, and run. In addition, we would no longer be plagued with lack of manufacturer support when we encountered obscure bugs. And maybe, hopefully, the eternal elusive goal of software portability across different vendors' platforms would finally be available. Some highlights of our prototyping efforts are described.

Breaking open the set top box

NASA Astrophysics Data System (ADS)

Banks, David; Wiley, Anthony; Catania, Nicolas; Coles, Alastair N.; Smith, Duncan; Baynham, Simon; Deliot, Eric; Chidzey, Rod

1998-02-01

In this paper we describe the work being done at HP Labs Bristol in the area of home networks and gateways. This work is based on the idea of breaking open the set top box by physically separating the access network specific functions from the application specific functions. The access network specific functions reside in an access network gateway that can be shared by many end user devices. The first section of the paper present the philosophy behind this approach. The end user devices and the access network gateways must be interconnected by a high bandwidth network which can offer a bounded delay service for delay sensitive traffic. We are advocating the use of IEEE 1394 for this network, and the next section of the paper gives a brief introduction to this technology. We then describe a prototype digital video broadcasting satellite compliant gateway that we have built. This gateway could be used, for example, by a PC for receiving a data service or by a digital TV for receiving an MPEG-2 video service. A control architecture is the presented which uses a PC application to provide a web based user interface to the system. Finally, we provide details of our work on extending the reach of IEEE 1394 and its standardization status.

Detection of Protein Complexes Based on Penalized Matrix Decomposition in a Sparse Protein⁻Protein Interaction Network.

PubMed

Cao, Buwen; Deng, Shuguang; Qin, Hua; Ding, Pingjian; Chen, Shaopeng; Li, Guanghui

2018-06-15

High-throughput technology has generated large-scale protein interaction data, which is crucial in our understanding of biological organisms. Many complex identification algorithms have been developed to determine protein complexes. However, these methods are only suitable for dense protein interaction networks, because their capabilities decrease rapidly when applied to sparse protein⁻protein interaction (PPI) networks. In this study, based on penalized matrix decomposition ( PMD ), a novel method of penalized matrix decomposition for the identification of protein complexes (i.e., PMD pc ) was developed to detect protein complexes in the human protein interaction network. This method mainly consists of three steps. First, the adjacent matrix of the protein interaction network is normalized. Second, the normalized matrix is decomposed into three factor matrices. The PMD pc method can detect protein complexes in sparse PPI networks by imposing appropriate constraints on factor matrices. Finally, the results of our method are compared with those of other methods in human PPI network. Experimental results show that our method can not only outperform classical algorithms, such as CFinder, ClusterONE, RRW, HC-PIN, and PCE-FR, but can also achieve an ideal overall performance in terms of a composite score consisting of F-measure, accuracy (ACC), and the maximum matching ratio (MMR).

PC-based note taking in patient-centred diagnostic interviews: a thematic analysis of patient opinion elicited using a pilot survey instrument.

PubMed

Barker, Fiona; Court, Gemma

2011-01-01

Computers are used increasingly in patient-clinician consultations. There is the potential for PC use to have an effect on the communication process. The aim of this preliminary study was to investigate patient opinion regarding the use of PC-based note taking during diagnostic vestibular assessments. We gave a simple four-item questionnaire to 100 consecutive patients attending for vestibular assessment at a secondary referral level primary care trust audiology service. Written responses to two of the questionnaire items were subject to an inductive thematic analysis. The questionnaire was acceptable to patients, none refused to complete it. Dominant themes identified suggest that patients do perceive consistent positive benefits from the use of PC-based note taking. This pilot study's short survey instrument is usable and may provide insights into patients' perceptions of computer use in a clinical setting.

Collaborative Simulation Grid: Multiscale Quantum-Mechanical/Classical Atomistic Simulations on Distributed PC Clusters in the US and Japan

NASA Technical Reports Server (NTRS)

Kikuchi, Hideaki; Kalia, Rajiv; Nakano, Aiichiro; Vashishta, Priya; Iyetomi, Hiroshi; Ogata, Shuji; Kouno, Takahisa; Shimojo, Fuyuki; Tsuruta, Kanji; Saini, Subhash;

Keys to success of a community of clinical practice in primary care: a qualitative evaluation of the ECOPIH project.

PubMed

Lacasta Tintorer, David; Manresa Domínguez, Josep Maria; Pujol-Rivera, Enriqueta; Flayeh Beneyto, Souhel; Mundet Tuduri, Xavier; Saigí-Rubió, Francesc

2018-05-09

The current reality of primary care (PC) makes it essential to have telemedicine systems available to facilitate communication between care levels. Communities of practice have great potential in terms of care and education, and that is why the Online Communication Tool between Primary and Hospital Care was created. This tool enables PC and non-GP specialist care (SC) professionals to raise clinical cases for consultation and to share information. The objective of this article is to explore healthcare professionals' views on communities of clinical practice (CoCPs) and the changes that need to be made in an uncontrolled real-life setting after more than two years of use. A descriptive-interpretative qualitative study was conducted on a total of 29 healthcare professionals who were users and non-users of a CoCP using 2 focus groups, 3 triangular groups and 5 individual interviews. There were 18 women, 21 physicians and 8 nurses. Of the interviewees, 21 were PC professionals, 24 were users of a CoCP and 7 held managerial positions. For a system of communication between PC and SC to become a tool that is habitually used and very useful, the interviewees considered that it would have to be able to find quick, effective solutions to the queries raised, based on up-to-date information that is directly applicable to daily clinical practice. Contact should be virtual - and probably collaborative - via a platform integrated into their habitual workstations and led by PC professionals. Organisational changes should be implemented to enable users to have more time in their working day to spend on the tool, and professionals should have a proactive attitude in order to make the most if its potential. It is also important to make certain technological changes, basically aimed at improving the tool's accessibility, by integrating it into habitual clinical workstations. The collaborative tool that provides reliable, up-to-date information that is highly transferrable to clinical practice is valued for its effectiveness, efficiency and educational capacity. In order to make the most of its potential in terms of care and education, organisational changes and techniques are required to foster greater use.

Earthquakes in the Classroom, Las Vegas, NV: The Nevada Educational Seismic Network (NESN)

NASA Astrophysics Data System (ADS)

Hopkins, J.; Snelson, C. M.; Zaragoza, S. A.; Smith, K.; Depolo, D.

2002-12-01

Geophysics is a term guaranteed to strike fear into the heart of the bravest high school science student. Using math to describe the earth can involve complex equations that can only be deciphered by enigmatic computer programs. But high school science students in the Las Vegas Valley have been given a unique opportunity to gather important research information while learning about geophysics, real-time data collection, and Internet communications in a less threatening environment. Three seismograph stations funded by the Department of Energy and the University of Nevada, Las Vegas have been installed in three different high schools in the Clark County School District. These three stations form a triangle in the Las Vegas Valley basin covering areas where the basin depths change significantly. The geophones are buried outside and a cable connects the sensors and GPS receiver to a digitizer on a local PC. The data is transmitted continuously in real-time via Internet communications protocols to the Seismic Explorer Monitoring Network. There it is available to all schools and to researchers who will analyze the data. These short-period geophones will record small local earthquakes and larger more distant events contributing to real-time seismic network operations in southern Nevada. Students at a school site are able to see live real-time data from other school stations as well as from seismograph stations in southern Nevada, the western US, and the world. Mentored by researchers at the University of Nevada, Reno and University of Nevada, Las Vegas, the teachers and students conduct simple waveform analysis to determine earthquake locations and magnitudes and operate the stations in this cooperative research effort. The goal of this partnership between secondary and university educational systems is to create a successful alliance that will benefit the research community as well as the classroom teacher and his/her students. Researchers will use the data collected from the schools in studies of the structure in the Las Vegas Valley basin and evaluation of the local seismicity. A major goal for the secondary teacher is the development of lesson plans that will use the collected data as a learning tool to help their students gain a better understanding of specific scientific concepts. Using the latest software and data communications technologies, students participating in this project will be on the cutting edge of establishing a model for urban seismic networks.

Educational network comparative analysis of small groups: Short- and long-term communications

NASA Astrophysics Data System (ADS)

Berg, D. B.; Zvereva, O. M.; Nazarova, Yu. Yu.; Chepurov, E. G.; Kokovin, A. V.; Ranyuk, S. V.

2017-11-01

The present study is devoted to the discussion of small group communication network structures. These communications were observed in student groups, where actors were united with a regular educational activity. The comparative analysis was carried out for networks of short-term (1 hour) and long-term (4 weeks) communications, it was based on seven structural parameters, and consisted of two stages. At the first stage, differences between the network graphs were examined, and the random corresponding Bernoulli graphs were built. At the second stage, revealed differences were compared. Calculations were performed using UCINET software framework. It was found out that networks of long-term and short-term communications are quite different: the structure of a short-term communication network is close to a random one, whereas the most of long-term communication network parameters differ from the corresponding random ones by more than 30%. This difference can be explained by strong "noisiness" of a short-term communication network, and the lack of social in it.

Long-range interactions and parallel scalability in molecular simulations

NASA Astrophysics Data System (ADS)

Patra, Michael; Hyvönen, Marja T.; Falck, Emma; Sabouri-Ghomi, Mohsen; Vattulainen, Ilpo; Karttunen, Mikko

2007-01-01

Typical biomolecular systems such as cellular membranes, DNA, and protein complexes are highly charged. Thus, efficient and accurate treatment of electrostatic interactions is of great importance in computational modeling of such systems. We have employed the GROMACS simulation package to perform extensive benchmarking of different commonly used electrostatic schemes on a range of computer architectures (Pentium-4, IBM Power 4, and Apple/IBM G5) for single processor and parallel performance up to 8 nodes—we have also tested the scalability on four different networks, namely Infiniband, GigaBit Ethernet, Fast Ethernet, and nearly uniform memory architecture, i.e. communication between CPUs is possible by directly reading from or writing to other CPUs' local memory. It turns out that the particle-mesh Ewald method (PME) performs surprisingly well and offers competitive performance unless parallel runs on PC hardware with older network infrastructure are needed. Lipid bilayers of sizes 128, 512 and 2048 lipid molecules were used as the test systems representing typical cases encountered in biomolecular simulations. Our results enable an accurate prediction of computational speed on most current computing systems, both for serial and parallel runs. These results should be helpful in, for example, choosing the most suitable configuration for a small departmental computer cluster.

GP and nurses' perceptions of how after hours care for people receiving palliative care at home could be improved: a mixed methods study.

PubMed

Tan, Heather M; O'Connor, Margaret M; Miles, Gail; Klein, Britt; Schattner, Peter

2009-09-14

Primary health care providers play a dominant role in the provision of palliative care (PC) in Australia but many gaps in after hours service remain. In some rural areas only 19% of people receiving palliative care achieve their goal of dying at home. This study, which builds on an earlier qualitative phase of the project, investigates the gaps in care from the perspective of general practitioners (GPs) and PC nurses. Questionnaires, developed from the outcomes of the earlier phase, and containing both structured and open ended questions, were distributed through Divisions of General Practice (1 urban, 1 rural, 1 mixed) to GPs (n = 524) and through a special interest group to palliative care nurses (n = 122) in both rural and urban areas. Questionnaires were returned by 114 GPs (22%) and 52 nurses (43%). The majority of GPs were associated with a practice which provided some after hours services but PC was not a strong focus for most. This was reflected in low levels of PC training, limited awareness of the existence of after hours triage services in their area, and of the availability of Enhanced Primary Care (EPC) Medicare items for care planning for palliative patients. However, more than half of both nurses and GPs were aware of accessible PC resources.Factors such as poor communication and limited availability of after hours services were identified the as most likely to impact negatively on service provision. Strategies considered most likely to improve after hours services were individual patient protocols, palliative care trained respite carers and regular multidisciplinary meetings that included the GP. While some of the identified gaps can only be met by long term funding and policy change, educational tools for use in training programs in PC for health professionals, which focus on the utilisation of EPC Medicare items in palliative care planning, the development of advance care plans and good communication between members of multidisciplinary teams, which include the GP, may enhance after hours service provision for patients receiving palliative care at home. The role of locums in after PC is an area for further research.

KSC-75PC-0365

NASA Image and Video Library

1975-07-17

CAPE CANAVERAL, Fla. -- Technicians check out the Symphonie-B spacecraft during launch preparations at KSC. Symphonie is a synchronous-orbit communications satellite, jointly owned and managed by West Germany and France. Photo credit: NASA

Lost opportunities to prevent early onset type 2 diabetes mellitus after a pregnancy complicated by gestational diabetes

PubMed Central

Bernstein, Judith A; McCloskey, Lois; Gebel, Christina M; Iverson, Ronald E; Lee-Parritz, Aviva

2016-01-01

Objectives Gestational diabetes mellitus (GDM) greatly increases the risk of developing diabetes in the decade after delivery, but few women receive appropriately timed postpartum glucose testing (PPGT) or a referral to primary care (PC) for continued monitoring. This qualitative study was designed to identify barriers and facilitators to testing and referral from patient and providers' perspectives. Methods We interviewed patients and clinicians in depth about knowledge, values, priorities, challenges, and recommendations for increasing PPGT rates and PC linkage. Interviews were coded with NVIVO data analysis software, and analyzed using an implementation science framework. Results Women reported motivation to address GDM for the health of the fetus. Most women did not anticipate future diabetes for themselves, and focused on delivery outcomes rather than future health risks. Patients sought and received reassurance from clinicians, and were unlikely to discuss early onset following GDM or preventive measures. PPGT barriers described by patients included provider not mentioning the test or setting it up, transportation difficulties, work responsibilities, fatigue, concerns about fasting while breastfeeding, and timing of the test after discharge from obstetrics, and no referral to PC for follow-up. Practitioners described limited communication among multiple care providers during pregnancy and delivery, systems issues, and separation of obstetrics from PC. Conclusions Patients' barriers to PPGT included low motivation for self-care, structural obstacles, and competing priorities. Providers reported the need to balance risk with reassurance, and identified systems failures related to test timing, limitations of electronic medical record systems (EMR), lack of referrals to PC, and inadequate communication between specialties. Prevention of early onset has great potential for medical cost savings and improvements in quality of life. PMID:27347422

Lost opportunities to prevent early onset type 2 diabetes mellitus after a pregnancy complicated by gestational diabetes.

PubMed

Bernstein, Judith A; McCloskey, Lois; Gebel, Christina M; Iverson, Ronald E; Lee-Parritz, Aviva

2016-01-01

Gestational diabetes mellitus (GDM) greatly increases the risk of developing diabetes in the decade after delivery, but few women receive appropriately timed postpartum glucose testing (PPGT) or a referral to primary care (PC) for continued monitoring. This qualitative study was designed to identify barriers and facilitators to testing and referral from patient and providers' perspectives. We interviewed patients and clinicians in depth about knowledge, values, priorities, challenges, and recommendations for increasing PPGT rates and PC linkage. Interviews were coded with NVIVO data analysis software, and analyzed using an implementation science framework. Women reported motivation to address GDM for the health of the fetus. Most women did not anticipate future diabetes for themselves, and focused on delivery outcomes rather than future health risks. Patients sought and received reassurance from clinicians, and were unlikely to discuss early onset following GDM or preventive measures. PPGT barriers described by patients included provider not mentioning the test or setting it up, transportation difficulties, work responsibilities, fatigue, concerns about fasting while breastfeeding, and timing of the test after discharge from obstetrics, and no referral to PC for follow-up. Practitioners described limited communication among multiple care providers during pregnancy and delivery, systems issues, and separation of obstetrics from PC. Patients' barriers to PPGT included low motivation for self-care, structural obstacles, and competing priorities. Providers reported the need to balance risk with reassurance, and identified systems failures related to test timing, limitations of electronic medical record systems (EMR), lack of referrals to PC, and inadequate communication between specialties. Prevention of early onset has great potential for medical cost savings and improvements in quality of life.

Neutral endopeptidase inhibits neuropeptide-mediated transactivation of the insulin-like growth factor receptor-Akt cell survival pathway.

PubMed

Sumitomo, M; Milowsky, M I; Shen, R; Navarro, D; Dai, J; Asano, T; Hayakawa, M; Nanus, D M

2001-04-15

G-protein coupled receptor (GPCR) agonists such as neuropeptides activate the insulin-like growth factor-1 receptor (IGF-IR) or the serine-threonine protein kinase Akt, suggesting that neuropeptides-GPCR signaling can cross-communicate with IGF-IR-Akt signaling pathways. Neutral endopeptidase 24.11 (NEP) is a cell-surface peptidase that cleaves and inactivates the neuropeptides endothelin-1 (ET-1) and bombesin, which are implicated in progression to androgen-independent prostate cancer (PC). We investigated the mechanisms of NEP regulation of neuropeptide-mediated cell survival in PC cells, including whether neuropeptide substrates of NEP induce phosphorylations of IGF-IR and Akt in PC cells. Western analyses revealed ET-1 and bombesin treatment induced phosphorylation of IGF-IRbeta and Akt independent of IGF-I in TSU-Pr1, DU145, and PC-3 PC cells, which lack NEP expression, but not in NEP-expressing LNCaP cells. Recombinant NEP and induced NEP expression in TSU-Pr1 cells using a tetracycline-repressive expression system inhibited ET-1-mediated phosphorylation of IGF-IRbeta and Akt, and blocked the protective effects of ET-1 against apoptosis induced by serum starvation. Incubation of TSU-Pr1 cells with specific kinase inhibitors together with ET-1 or bombesin showed that IGF-IR activation is required for neuropeptide-induced Akt phosphorylation, and that neuropeptide-induced Akt activation is predominantly mediated by Src and phosphatidylinositol 3-kinase but not by mitogen-activated protein kinase or protein kinase C. These data show that the neuropeptides ET-1 and bombesin stimulate ligand-independent activation of the IGF-IR, which results in Akt activation, and that this cross-communication between GPCR and IGF-IR signaling is inhibited by NEP.

What systemic factors contribute to collaboration between primary care and public health sectors? An interpretive descriptive study.

PubMed

Wong, Sabrina T; MacDonald, Marjorie; Martin-Misener, Ruth; Meagher-Stewart, Donna; O'Mara, Linda; Valaitis, Ruta K

2017-12-01

Purposefully building stronger collaborations between primary care (PC) and public health (PH) is one approach to strengthening primary health care. The purpose of this paper is to report: 1) what systemic factors influence collaborations between PC and PH; and 2) how systemic factors interact and could influence collaboration. This interpretive descriptive study used purposive and snowball sampling to recruit and conduct interviews with PC and PH key informants in British Columbia (n = 20), Ontario (n = 19), and Nova Scotia (n = 21), Canada. Other participants (n = 14) were knowledgeable about collaborations and were located in various Canadian provinces or working at a national level. Data were organized into codes and thematic analysis was completed using NVivo. The frequency of "sources" (individual transcripts), "references" (quotes), and matrix queries were used to identify potential relationships between factors. We conducted a total of 70 in-depth interviews with 74 participants working in either PC (n = 33) or PH (n = 32), both PC and PH (n = 7), or neither sector (n = 2). Participant roles included direct service providers (n = 17), senior program managers (n = 14), executive officers (n = 11), and middle managers (n = 10). Seven systemic factors for collaboration were identified: 1) health service structures that promote collaboration; 2) funding models and financial incentives supporting collaboration; 3) governmental and regulatory policies and mandates for collaboration; 4) power relations; 5) harmonized information and communication infrastructure; 6) targeted professional education; and 7) formal systems leaders as collaborative champions. Most themes were discussed with equal frequency between PC and PH. An assessment of the system level context (i.e., provincial and regional organization and funding of PC and PH, history of government in successful implementation of health care reform, etc) along with these seven system level factors could assist other jurisdictions in moving towards increased PC and PH collaboration. There was some variation in the importance of the themes across provinces. British Columbia participants more frequently discussed system structures that could promote collaboration, power relations, harmonized information and communication structures, formal systems leaders as collaboration champions and targeted professional education. Ontario participants most frequently discussed governmental and regulatory policies and mandates for collaboration.

76 FR 23812 - Reliability and Continuity of Communications Networks, Including Broadband Technologies; Effects...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-28

... FEDERAL COMMUNICATIONS COMMISSION [PS Docket Nos. 11-60 and 10-92; ET Docket No. 06-119] Reliability and Continuity of Communications Networks, Including Broadband Technologies; Effects on Broadband Communications Networks of Damage or Failure of Network Equipment or Severe Overload; Independent Panel Reviewing...

Microcomputer Applications with PC LAN (Local Area Network) in Battleships.

DTIC Science & Technology

1988-12-01

NETWORKS 5 C. TRANSMISSION TECHNIQUES 6 D. MEDIUM ACCESS CONTROL METHODS 6 1. CSMA CD 6 2. Control Token 7 3. Slotted Ring 7 E...network model in the Turkish Battleships will employ the broadband technique. D. MEDIUM ACCESS CONTROL METHODS The access method is one of the most...better performance at heavier loads. 3. Slotted Ring This method is used with a ring network. The ring is initialized to contain a fixed number of

Dynamical graph theory networks techniques for the analysis of sparse connectivity networks in dementia

NASA Astrophysics Data System (ADS)

Tahmassebi, Amirhessam; Pinker-Domenig, Katja; Wengert, Georg; Lobbes, Marc; Stadlbauer, Andreas; Romero, Francisco J.; Morales, Diego P.; Castillo, Encarnacion; Garcia, Antonio; Botella, Guillermo; Meyer-Bäse, Anke

2017-05-01

Graph network models in dementia have become an important computational technique in neuroscience to study fundamental organizational principles of brain structure and function of neurodegenerative diseases such as dementia. The graph connectivity is reflected in the connectome, the complete set of structural and functional connections of the graph network, which is mostly based on simple Pearson correlation links. In contrast to simple Pearson correlation networks, the partial correlations (PC) only identify direct correlations while indirect associations are eliminated. In addition to this, the state-of-the-art techniques in brain research are based on static graph theory, which is unable to capture the dynamic behavior of the brain connectivity, as it alters with disease evolution. We propose a new research avenue in neuroimaging connectomics based on combining dynamic graph network theory and modeling strategies at different time scales. We present the theoretical framework for area aggregation and time-scale modeling in brain networks as they pertain to disease evolution in dementia. This novel paradigm is extremely powerful, since we can derive both static parameters pertaining to node and area parameters, as well as dynamic parameters, such as system's eigenvalues. By implementing and analyzing dynamically both disease driven PC-networks and regular concentration networks, we reveal differences in the structure of these network that play an important role in the temporal evolution of this disease. The described research is key to advance biomedical research on novel disease prediction trajectories and dementia therapies.

Alternative Path Communication in Wide-Scale Cluster-Tree Wireless Sensor Networks Using Inactive Periods

PubMed Central

Leão, Erico; Montez, Carlos; Moraes, Ricardo; Portugal, Paulo; Vasques, Francisco

2017-01-01

The IEEE 802.15.4/ZigBee cluster-tree topology is a suitable technology to deploy wide-scale Wireless Sensor Networks (WSNs). These networks are usually designed to support convergecast traffic, where all communication paths go through the PAN (Personal Area Network) coordinator. Nevertheless, peer-to-peer communication relationships may be also required for different types of WSN applications. That is the typical case of sensor and actuator networks, where local control loops must be closed using a reduced number of communication hops. The use of communication schemes optimised just for the support of convergecast traffic may result in higher network congestion and in a potentially higher number of communication hops. Within this context, this paper proposes an Alternative-Route Definition (ARounD) communication scheme for WSNs. The underlying idea of ARounD is to setup alternative communication paths between specific source and destination nodes, avoiding congested cluster-tree paths. These alternative paths consider shorter inter-cluster paths, using a set of intermediate nodes to relay messages during their inactive periods in the cluster-tree network. Simulation results show that the ARounD communication scheme can significantly decrease the end-to-end communication delay, when compared to the use of standard cluster-tree communication schemes. Moreover, the ARounD communication scheme is able to reduce the network congestion around the PAN coordinator, enabling the reduction of the number of message drops due to queue overflows in the cluster-tree network. PMID:28481245

Alternative Path Communication in Wide-Scale Cluster-Tree Wireless Sensor Networks Using Inactive Periods.

PubMed

Leão, Erico; Montez, Carlos; Moraes, Ricardo; Portugal, Paulo; Vasques, Francisco

2017-05-06

The IEEE 802.15.4/ZigBee cluster-tree topology is a suitable technology to deploy wide-scale Wireless Sensor Networks (WSNs). These networks are usually designed to support convergecast traffic, where all communication paths go through the PAN (Personal Area Network) coordinator. Nevertheless, peer-to-peer communication relationships may be also required for different types of WSN applications. That is the typical case of sensor and actuator networks, where local control loops must be closed using a reduced number of communication hops. The use of communication schemes optimised just for the support of convergecast traffic may result in higher network congestion and in a potentially higher number of communication hops. Within this context, this paper proposes an Alternative-Route Definition (ARounD) communication scheme for WSNs. The underlying idea of ARounD is to setup alternative communication paths between specific source and destination nodes, avoiding congested cluster-tree paths. These alternative paths consider shorter inter-cluster paths, using a set of intermediate nodes to relay messages during their inactive periods in the cluster-tree network. Simulation results show that the ARounD communication scheme can significantly decrease the end-to-end communication delay, when compared to the use of standard cluster-tree communication schemes. Moreover, the ARounD communication scheme is able to reduce the network congestion around the PAN coordinator, enabling the reduction of the number of message drops due to queue overflows in the cluster-tree network.

Narrow Band Filter at 1550 nm Based on Quasi-One-Dimensional Photonic Crystal with a Mirror-Symmetric Heterostructure.

PubMed

Wang, Fang; Cheng, Yong Zhi; Wang, Xian; Zhang, Yi Nan; Nie, Yan; Gong, Rong Zhou

2018-06-27

In this paper, we present a high-efficiency narrow band filter (NBF) based on quasi-one-dimensional photonic crystal (PC) with a mirror symmetric heterostructure. Similarly to the Fabry-Perot-like resonance cavity, the alternately-arranged dielectric layers on both sides act as the high reflectance and the junction layers used as the defect mode of the quasi-one-dimensional PC, which can be designed as a NBF. The critical conditions for the narrow pass band with high transmittance are demonstrated and analyzed by simulation and experiment. The simulation results indicate that the transmission peak of the quasi-one-dimensional PC-based NBF is up to 95.99% at the telecommunication wavelength of 1550 nm, which agrees well with the experiment. Furthermore, the influences of the periodicity and thickness of dielectric layers on the transmission properties of the PC-based NBF also have been studied numerically. Due to its favorable properties of PC-based NBF, it is can be found to have many potential applications, such as detection, sensing, and communication.

Apparatus and method for data communication in an energy distribution network

DOEpatents

Hussain, Mohsin; LaPorte, Brock; Uebel, Udo; Zia, Aftab

2014-07-08

A system for communicating information on an energy distribution network is disclosed. In one embodiment, the system includes a local supervisor on a communication network, wherein the local supervisor can collect data from one or more energy generation/monitoring devices. The system also includes a command center on the communication network, wherein the command center can generate one or more commands for controlling the one or more energy generation devices. The local supervisor can periodically transmit a data signal indicative of the data to the command center via a first channel of the communication network at a first interval. The local supervisor can also periodically transmit a request for a command to the command center via a second channel of the communication network at a second interval shorter than the first interval. This channel configuration provides effective data communication without a significant increase in the use of network resources.

Computer hardware fault administration

DOEpatents

Archer, Charles J.; Megerian, Mark G.; Ratterman, Joseph D.; Smith, Brian E.

2010-09-14

Computer hardware fault administration carried out in a parallel computer, where the parallel computer includes a plurality of compute nodes. The compute nodes are coupled for data communications by at least two independent data communications networks, where each data communications network includes data communications links connected to the compute nodes. Typical embodiments carry out hardware fault administration by identifying a location of a defective link in the first data communications network of the parallel computer and routing communications data around the defective link through the second data communications network of the parallel computer.

Palliative Care in Critical Care Settings: A Systematic Review of Communication-Based Competencies Essential for Patient and Family Satisfaction.

PubMed

Schram, Andrew W; Hougham, Gavin W; Meltzer, David O; Ruhnke, Gregory W

2017-11-01

There is an emerging literature on the physician competencies most meaningful to patients and their families. However, there has been no systematic review on physician competency domains outside direct clinical care most important for patient- and family-centered outcomes in critical care settings at the end of life (EOL). Physician competencies are an essential component of palliative care (PC) provided at the EOL, but the literature on those competencies relevant for patient and family satisfaction is limited. A systematic review of this important topic can inform future research and assist in curricular development. Review of qualitative and quantitative empirical studies of the impact of physician competencies on patient- and family-reported outcomes conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines for systematic reviews. The data sources used were PubMed, MEDLINE, Web of Science, and Google Scholar. Fifteen studies (5 qualitative and 10 quantitative) meeting inclusion and exclusion criteria were identified. The competencies identified as critical for the delivery of high-quality PC in critical care settings are prognostication, conflict mediation, empathic communication, and family-centered aspects of care, the latter being the competency most frequently acknowledged in the literature identified. Prognostication, conflict mediation, empathic communication, and family-centered aspects of care are the most important identified competencies for patient- and family-centered PC in critical care settings. Incorporation of education on these competencies is likely to improve patient and family satisfaction with EOL care.

Open source system OpenVPN in a function of Virtual Private Network

NASA Astrophysics Data System (ADS)

Skendzic, A.; Kovacic, B.

2017-05-01

Using of Virtual Private Networks (VPN) can establish high security level in network communication. VPN technology enables high security networking using distributed or public network infrastructure. VPN uses different security and managing rules inside networks. It can be set up using different communication channels like Internet or separate ISP communication infrastructure. VPN private network makes security communication channel over public network between two endpoints (computers). OpenVPN is an open source software product under GNU General Public License (GPL) that can be used to establish VPN communication between two computers inside business local network over public communication infrastructure. It uses special security protocols and 256-bit Encryption and it is capable of traversing network address translators (NATs) and firewalls. It allows computers to authenticate each other using a pre-shared secret key, certificates or username and password. This work gives review of VPN technology with a special accent on OpenVPN. This paper will also give comparison and financial benefits of using open source VPN software in business environment.

75 FR 49870 - Effects on Broadband Communications Networks of Damage to or Failure of Network Equipment or...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-16

... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Chapter I [PS Docket No. 10-92; DA 10-1357] Effects on Broadband Communications Networks of Damage to or Failure of Network Equipment or Severe Overload AGENCY: Federal Communications Commission ACTION: Proposed rule; extension of reply comment date. SUMMARY: This...

Reliable Communication Models in Interdependent Critical Infrastructure Networks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Sangkeun; Chinthavali, Supriya; Shankar, Mallikarjun

Modern critical infrastructure networks are becoming increasingly interdependent where the failures in one network may cascade to other dependent networks, causing severe widespread national-scale failures. A number of previous efforts have been made to analyze the resiliency and robustness of interdependent networks based on different models. However, communication network, which plays an important role in today's infrastructures to detect and handle failures, has attracted little attention in the interdependency studies, and no previous models have captured enough practical features in the critical infrastructure networks. In this paper, we study the interdependencies between communication network and other kinds of critical infrastructuremore » networks with an aim to identify vulnerable components and design resilient communication networks. We propose several interdependency models that systematically capture various features and dynamics of failures spreading in critical infrastructure networks. We also discuss several research challenges in building reliable communication solutions to handle failures in these models.« less

A Hybrid Satellite-Terrestrial Approach to Aeronautical Communication Networks

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.; Chomos, Gerald J.; Griner, James H.; Mainger, Steven W.; Martzaklis, Konstantinos S.; Kachmar, Brian A.

2000-01-01

Rapid growth in air travel has been projected to continue for the foreseeable future. To maintain a safe and efficient national and global aviation system, significant advances in communications systems supporting aviation are required. Satellites will increasingly play a critical role in the aeronautical communications network. At the same time, current ground-based communications links, primarily very high frequency (VHF), will continue to be employed due to cost advantages and legacy issues. Hence a hybrid satellite-terrestrial network, or group of networks, will emerge. The increased complexity of future aeronautical communications networks dictates that system-level modeling be employed to obtain an optimal system fulfilling a majority of user needs. The NASA Glenn Research Center is investigating the current and potential future state of aeronautical communications, and is developing a simulation and modeling program to research future communications architectures for national and global aeronautical needs. This paper describes the primary requirements, the current infrastructure, and emerging trends of aeronautical communications, including a growing role for satellite communications. The need for a hybrid communications system architecture approach including both satellite and ground-based communications links is explained. Future aeronautical communication network topologies and key issues in simulation and modeling of future aeronautical communications systems are described.

Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity

PubMed Central

Care, Matthew A.; Stephenson, Sophie J.; Barnes, Nicholas A.; Fan, Im; Zougman, Alexandre; El-Sherbiny, Yasser M.; Vital, Edward M.; Westhead, David R.; Tooze, Reuben M.

2016-01-01

Plasma cells (PCs) as effectors of humoral immunity produce Igs to match pathogenic insult. Emerging data suggest more diverse roles exist for PCs as regulators of immune and inflammatory responses via secretion of factors other than Igs. The extent to which such responses are preprogrammed in B-lineage cells or can be induced in PCs by the microenvironment is unknown. In this study, we dissect the impact of IFNs on the regulatory networks of human PCs. We show that core PC programs are unaffected, whereas PCs respond to IFNs with distinctive transcriptional responses. The IFN-stimulated gene 15 (ISG15) system emerges as a major transcriptional output induced in a sustained fashion by IFN-α in PCs and linked both to intracellular conjugation and ISG15 secretion. This leads to the identification of ISG15-secreting plasmablasts/PCs in patients with active systemic lupus erythematosus. Thus, ISG15-secreting PCs represent a distinct proinflammatory PC subset providing an Ig-independent mechanism of PC action in human autoimmunity. PMID:27357150

Overview of NASA communications infrastructure

NASA Technical Reports Server (NTRS)

Arnold, Ray J.; Fuechsel, Charles

1991-01-01

The infrastructure of NASA communications systems for effecting coordination across NASA offices and with the national and international research and technological communities is discussed. The offices and networks of the communication system include the Office of Space Science and Applications (OSSA), which manages all NASA missions, and the Office of Space Operations, which furnishes communication support through the NASCOM, the mission critical communications support network, and the Program Support Communications network. The NASA Science Internet was established by OSSA to centrally manage, develop, and operate an integrated computer network service dedicated to NASA's space science and application research. Planned for the future is the National Research and Education Network, which will provide communications infrastructure to enhance science resources at a national level.

GLOBECOM '85 - Global Telecommunications Conference, New Orleans, LA, December 2-5, 1985, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

Various papers on global telecommunications are presented. The general topics addressed include: multiservice integration with optical fibers, multicompany owned telecommunication networks, softworks quality and reliability, advanced on-board processing, impact of new services and systems on operations and maintenance, analytical studies of protocols for data communication networks, topics in packet radio networking, CCITT No. 7 to support new services, document processing and communication, antenna technology and system aspects in satellite communications. Also considered are: communication systems modelling methodology, experimental integrated local area voice/data nets, spread spectrum communications, motion video at the DS-0 rate, optical and data communications, intelligent work stations, switch performance analysis, novel radio communication systems, wireless local networks, ISDN services, LAN communication protocols, user-system interface, radio propagation and performance, mobile satellite system, software for computer networks, VLSI for ISDN terminals, quality management, man-machine interfaces in switching, and local area network performance.

Communication devices for network-hopping communications and methods of network-hopping communications

DOEpatents

Buttles, John W [Idaho Falls, ID

2011-12-20

Wireless communication devices include a software-defined radio coupled to processing circuitry. The processing circuitry is configured to execute computer programming code. Storage media is coupled to the processing circuitry and includes computer programming code configured to cause the processing circuitry to configure and reconfigure the software-defined radio to operate on each of a plurality of communication networks according to a selected sequence. Methods for communicating with a wireless device and methods of wireless network-hopping are also disclosed.

Communication devices for network-hopping communications and methods of network-hopping communications

DOEpatents

Buttles, John W

2013-04-23

Wireless communication devices include a software-defined radio coupled to processing circuitry. The system controller is configured to execute computer programming code. Storage media is coupled to the system controller and includes computer programming code configured to cause the system controller to configure and reconfigure the software-defined radio to operate on each of a plurality of communication networks according to a selected sequence. Methods for communicating with a wireless device and methods of wireless network-hopping are also disclosed.

GLOBECOM '87 - Global Telecommunications Conference, Tokyo, Japan, Nov. 15-18, 1987, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

The present conference on global telecommunications discusses topics in the fields of Integrated Services Digital Network (ISDN) technology field trial planning and results to date, motion video coding, ISDN networking, future network communications security, flexible and intelligent voice/data networks, Asian and Pacific lightwave and radio systems, subscriber radio systems, the performance of distributed systems, signal processing theory, satellite communications modulation and coding, and terminals for the handicapped. Also discussed are knowledge-based technologies for communications systems, future satellite transmissions, high quality image services, novel digital signal processors, broadband network access interface, traffic engineering for ISDN design and planning, telecommunications software, coherent optical communications, multimedia terminal systems, advanced speed coding, portable and mobile radio communications, multi-Gbit/second lightwave transmission systems, enhanced capability digital terminals, communications network reliability, advanced antimultipath fading techniques, undersea lightwave transmission, image coding, modulation and synchronization, adaptive signal processing, integrated optical devices, VLSI technologies for ISDN, field performance of packet switching, CSMA protocols, optical transport system architectures for broadband ISDN, mobile satellite communications, indoor wireless communication, echo cancellation in communications, and distributed network algorithms.

Magnetic anisotropy of metal functionalized phthalocyanine 2D networks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu, Guojun; Zhang, Yun; Xiao, Huaping, E-mail: hpxiao@xtu.edu.cn

2016-06-15

The magnetic anisotropy of metal including Cr, Mn, Fe, Co, Mo, Tc, Ru, Rh, W, Re, Os, Ir atoms functionalized phthalocyanine networks have been investigated with first-principles calculations. The magnetic moments can be expressed as 8-n μ{sub B} with n the electronic number of outmost d shell in the transition metals. The huge magnetocrystalline anisotropy energy (MAE) is obtained by torque method. Especially, the MAE of Re functionalized phthalocyanine network is about 20 meV with an easy axis perpendicular to the plane of phthalocyanine network. The MAE is further manipulated by applying the external biaxial strain. It is found thatmore » the MAE is linear increasing with the external strain in the range of −2% to 2%. Our results indicate an effective approach to modulate the MAE for practical application. - Graphical abstract: The charge density redistribution (ρ{sub MPc}-ρ{sub M}-ρ{sub Pc}) and spin density of the CoPc molecule, from top- and side-views. Purple and green isosurfaces indicate charge depletion and accumulation, respectively. Display Omitted.« less

Training the Workforce: Description of a Longitudinal Interdisciplinary Education and Mentoring Program in Palliative Care.

PubMed

Levine, Stacie; O'Mahony, Sean; Baron, Aliza; Ansari, Aziz; Deamant, Catherine; Frader, Joel; Leyva, Ileana; Marschke, Michael; Preodor, Michael

2017-04-01

The rapid increase in demand for palliative care (PC) services has led to concerns regarding workforce shortages and threats to the resiliency of PC teams. To describe the development, implementation, and evaluation of a regional interdisciplinary training program in PC. Thirty nurse and physician fellows representing 22 health systems across the Chicago region participated in a two-year PC training program. The curriculum was delivered through multiple conferences, self-directed e-learning, and individualized mentoring by expert local faculty (mentors). Fellows shadowed mentors' clinical practices and received guidance on designing, implementing, and evaluating a practice improvement project to address gaps in PC at their institutions. Enduring, interdisciplinary relationships were built at all levels across health care organizations. Fellows made significant increases in knowledge and self-reported confidence in adult and pediatric PC and program development skills and frequency performing these skills. Fellows and mentors reported high satisfaction with the educational program. This interdisciplinary PC training model addressed local workforce issues by increasing the number of clinicians capable of providing PC. Unique features include individualized longitudinal mentoring, interdisciplinary education, on-site project implementation, and local network building. Future research will address the impact of the addition of social work and chaplain trainees to the program. Copyright © 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

Terminal-oriented computer-communication networks.

NASA Technical Reports Server (NTRS)

Schwartz, M.; Boorstyn, R. R.; Pickholtz, R. L.

1972-01-01

Four examples of currently operating computer-communication networks are described in this tutorial paper. They include the TYMNET network, the GE Information Services network, the NASDAQ over-the-counter stock-quotation system, and the Computer Sciences Infonet. These networks all use programmable concentrators for combining a multiplicity of terminals. Included in the discussion for each network is a description of the overall network structure, the handling and transmission of messages, communication requirements, routing and reliability consideration where applicable, operating data and design specifications where available, and unique design features in the area of computer communications.

Experimental Observation of Two Features Unexpected from the Classical Theories of Rubber Elasticity

NASA Astrophysics Data System (ADS)

Nishi, Kengo; Fujii, Kenta; Chung, Ung-il; Shibayama, Mitsuhiro; Sakai, Takamasa

2017-12-01

Although the elastic modulus of a Gaussian chain network is thought to be successfully described by classical theories of rubber elasticity, such as the affine and phantom models, verification experiments are largely lacking owing to difficulties in precisely controlling of the network structure. We prepared well-defined model polymer networks experimentally, and measured the elastic modulus G for a broad range of polymer concentrations and connectivity probabilities, p . In our experiment, we observed two features that were distinct from those predicted by classical theories. First, we observed the critical behavior G ˜|p -pc|1.95 near the sol-gel transition. This scaling law is different from the prediction of classical theories, but can be explained by analogy between the electric conductivity of resistor networks and the elasticity of polymer networks. Here, pc is the sol-gel transition point. Furthermore, we found that the experimental G -p relations in the region above C* did not follow the affine or phantom theories. Instead, all the G /G0-p curves fell onto a single master curve when G was normalized by the elastic modulus at p =1 , G0. We show that the effective medium approximation for Gaussian chain networks explains this master curve.

Determining a bisection bandwidth for a multi-node data communications network

DOEpatents

Faraj, Ahmad A.

2010-01-26

Methods, systems, and products are disclosed for determining a bisection bandwidth for a multi-node data communications network that include: partitioning nodes in the network into a first sub-network and a second sub-network in dependence upon a topology of the network; sending, by each node in the first sub-network to a destination node in the second sub-network, a first message having a predetermined message size; receiving, by each node in the first sub-network from a source node in the second sub-network, a second message; measuring, by each node in the first sub-network, the elapsed communications time between the sending of the first message and the receiving of the second message; selecting the longest elapsed communications time; and calculating the bisection bandwidth for the network in dependence upon the number of the nodes in the first sub-network, the predetermined message size of the first test message, and the longest elapsed communications time.

Multispectral image fusion using neural networks

NASA Technical Reports Server (NTRS)

Kagel, J. H.; Platt, C. A.; Donaven, T. W.; Samstad, E. A.

1990-01-01

A prototype system is being developed to demonstrate the use of neural network hardware to fuse multispectral imagery. This system consists of a neural network IC on a motherboard, a circuit card assembly, and a set of software routines hosted by a PC-class computer. Research in support of this consists of neural network simulations fusing 4 to 7 bands of Landsat imagery and fusing (separately) multiple bands of synthetic imagery. The simulations, results, and a description of the prototype system are presented.

Risk Communication and the Pharmaceutical Industry: what is the reality?

PubMed

Edwards, Brian; Chakraborty, Sweta

2012-11-01

Risk communication is central to the risk management strategy of a pharmaceutical company. Pharmaceutical companies primarily communicate risk through labelling tools such as the Summary of Product Characteristics (SmPC), package insert, patient information leaflet (PIL) and the carton, which are currently regulated based on templates such as those of the EU. Recent research raises concern about how effective the SmPC is alone in communicating risk. There is some evidence that carton design can influence risk comprehension. Processes to check new trade names cannot be confused with existing names is a simple measure to mitigate one form of risk. Given the central role and the vast amount of resource that is consumed, it is surprising there has not been extensive original research to see whether product information such as the SmPC is a good tool for communicating risk. Recently, EU agencies have assessed the communication value of the PIL and revised the template and guidelines. However, no evaluation of user testing has been conducted at European level since the introduction of these new requirements. As regards 'Dear Healthcare Professional Communications', there is inconsistent evidence about their ability to change patient and physician behaviour. There is a dearth of evidence about what sort of communications materials are the most effective under which circumstances. The use of templates restricts the flexibility of companies to adapt their risk messages to their targets. Effective communication requires understanding how different audiences perceive the message and what the fundamental drivers are for altering patient and prescriber behaviour to be safer. This requires careful consideration of the relationship between risk communication, perception and management. However, the focus of a company's risk communication plan is normally on the International Conference on Harmonisation (ICH) regions and their regulations. Although the same regulatory tools are used globally, we are not aware of any research into their effectiveness outside the ICH regions. What listed companies can communicate about benefits and risks is strongly influenced by the obligations of companies to the market and investors. There needs to be internal coordination for simultaneous release. Internal communications about significant issues should be restricted to those who know how to manage the risk of insider dealing from internal communications that may later be made public. Unfortunately, there is evidence that some companies do not have a cohesive strategy for communicating risk which should take into account all forms of promotional material and company-sponsored information sources on the Internet. A pharmaceutical company is not the only stakeholder responsible for communicating risks on their products. However, the relative roles and responsibilities of all relevant stakeholders are not defined and are often unclear. This means it is difficult to evaluate whether a company's actions might be duplicative or inefficient. We recommend that companies have a dedicated communications group whose role is to coordinate the company's communications strategy mapped to objectives that have been agreed with key stakeholders apart from just regulatory agencies. This same group can assess effectiveness of the communications, monitor audience reaction and adjust the communication strategy accordingly.

The Workstation Approach to Laboratory Computing

PubMed Central

Crosby, P.A.; Malachowski, G.C.; Hall, B.R.; Stevens, V.; Gunn, B.J.; Hudson, S.; Schlosser, D.

1985-01-01

There is a need for a Laboratory Workstation which specifically addresses the problems associated with computing in the scientific laboratory. A workstation based on the IBM PC architecture and including a front end data acquisition system which communicates with a host computer via a high speed communications link; a new graphics display controller with hardware window management and window scrolling; and an integrated software package is described.

Performance of Wireless Unattended Sensor Network in Maritime Applications

DTIC Science & Technology

2007-06-01

longevity. Crossbow Technologies produces a number of gateways for use with their motes which include the MIB510, the MIB600 and the Stargate . The...MIB510 and MIB600 gateways require interface directly with a PC while he Stargate gateway interfaces remotely using the IEEE 802.11 standard for access...dedicated PC is unfeasible, the Stargate gateway allows remote access using the IEEE 802.11 standard. This can be accomplished via a Personal Computer

Primary care patients' perspectives of barriers and enablers of primary prevention and health promotion-a meta-ethnographic synthesis.

PubMed

Moreno-Peral, Patricia; Conejo-Cerón, Sonia; Fernández, Ana; Berenguera, Anna; Martínez-Andrés, María; Pons-Vigués, Mariona; Motrico, Emma; Rodríguez-Martín, Beatriz; Bellón, Juan A; Rubio-Valera, Maria

2015-01-01

Primary care (PC) patients have difficulties in committing to and incorporating primary prevention and health promotion (PP&HP) activities into their long-term care. We aimed to re-interpret, for the first time, qualitative findings regarding factors affecting PC patients' acceptance of PP&HP activities. A meta-ethnographic synthesis was generated following electronic and manual searches that retrieved 29 articles. Papers were reviewed and translated to produce a re-interpretation of the extracted concepts. The factors affecting PC patients' receptiveness to PP&HP activities were framed in a four-level ecological model (intrapersonal, interpersonal, institutional and environment and society). Intrapersonal factors (patients' beliefs/attitudes, knowledge, skills, self-concept, motivation and resources) were the most numerous, with almost 25 different factors. Public health education to modify erroneous beliefs and values regarding PP&HP could encourage a transition to healthier lifestyles. Health care professionals' abilities to communicate and involve patients in the decision-making process can act as facilitators. Biopsychosocial training (with emphasis on communication skills) for health professionals must start with undergraduates. Increased consultation time, the use of reminders, follow-up visits and tools for communicating risk and motivating patients could be applied at the intrapersonal level. Collaborative care involving other health professionals (nutritionists or psychotherapists) and family and community stakeholders (teachers or gym trainers) was important in developing healthier habits. Patients also cited barriers related to the built environment and socioeconomic difficulties that highlighted the need for policies promoting social justice and equity. Encouraging PP&HP using social marketing strategies and regulating media to control its impact on health were also cited. Only the perspectives of PC patients in the context of chronic conditions were considered thus limiting extrapolation to other contexts. Several factors affect PP&HP. This must be taken into account when designing PP&HP activities if they are to be successfully implemented and maintained in routine practice.

Primary Care Patients’ Perspectives of Barriers and Enablers of Primary Prevention and Health Promotion—A Meta-Ethnographic Synthesis

PubMed Central

Moreno-Peral, Patricia; Conejo-Cerón, Sonia; Fernández, Ana; Berenguera, Anna; Martínez-Andrés, María; Pons-Vigués, Mariona; Motrico, Emma; Rodríguez-Martín, Beatriz; Bellón, Juan A.; Rubio-Valera, Maria

2015-01-01

Background Primary care (PC) patients have difficulties in committing to and incorporating primary prevention and health promotion (PP&HP) activities into their long-term care. We aimed to re-interpret, for the first time, qualitative findings regarding factors affecting PC patients' acceptance of PP&HP activities. Methods and Findings A meta-ethnographic synthesis was generated following electronic and manual searches that retrieved 29 articles. Papers were reviewed and translated to produce a re-interpretation of the extracted concepts. The factors affecting PC patients' receptiveness to PP&HP activities were framed in a four-level ecological model (intrapersonal, interpersonal, institutional and environment and society). Intrapersonal factors (patients' beliefs/attitudes, knowledge, skills, self-concept, motivation and resources) were the most numerous, with almost 25 different factors. Public health education to modify erroneous beliefs and values regarding PP&HP could encourage a transition to healthier lifestyles. Health care professionals' abilities to communicate and involve patients in the decision-making process can act as facilitators. Biopsychosocial training (with emphasis on communication skills) for health professionals must start with undergraduates. Increased consultation time, the use of reminders, follow-up visits and tools for communicating risk and motivating patients could be applied at the intrapersonal level. Collaborative care involving other health professionals (nutritionists or psychotherapists) and family and community stakeholders (teachers or gym trainers) was important in developing healthier habits. Patients also cited barriers related to the built environment and socioeconomic difficulties that highlighted the need for policies promoting social justice and equity. Encouraging PP&HP using social marketing strategies and regulating media to control its impact on health were also cited. Only the perspectives of PC patients in the context of chronic conditions were considered thus limiting extrapolation to other contexts. Conclusions Several factors affect PP&HP. This must be taken into account when designing PP&HP activities if they are to be successfully implemented and maintained in routine practice. PMID:25938509

MONET 2009 PC Co-chairs' Message

NASA Astrophysics Data System (ADS)

Grifoni, Patrizia; Ferri, Fernando; Kondratova, Irina; D'Ulizia, Arianna

The research areas of mobile technologies, social networking and mobile services applications are receiving wide interest from private and public companies as well as from academic and research institutions.

Comparison of velocity patterns in an AComA aneurysm measured with 2D phase contrast MRI and simulated with CFD.

PubMed

Karmonik, Christof; Klucznik, Richard; Benndorf, Goetz

2008-01-01

Computational Fluid Dynamic (CFD) is increasingly being used for modeling hemodynamics in intracranial aneurysms. While CFD techniques are well established, need for validation of the results remains. By quantifying features in velocity patterns measured with 2D phase contrast magnetic resonance (pcMRI) in vivo and simulated with CFD, the role of pcMRI for providing reference data for the CFD simulation is explored. Unsteady CFD simulations were performed with inflow boundary conditions obtained from 2D pcMRI measurements of an aneurysm of the anterior communication artery. Intra-aneurysmal velocity profiles were recorded with 2D pcMRI and calculated with CFD. Relative areas of positive and negative velocity were calculated in these profiles for maximum and minimum inflow. Areas of positive and of negative velocity similar in shape were found in the velocity profiles obtained with both methods. Relative difference in size of the relative areas for the whole cardiac cycle ranged from 1%-25% (average 12%). 2D pcMRI is able to record velocity profiles in an aneurysm of the anterior commuting artery in vivo. These velocity profiles can serve as reference data for validation of CFD simulations. Further studies are needed to explore the role of pcMRI in the context of CFD simulations.

Research on social communication network evolution based on topology potential distribution

NASA Astrophysics Data System (ADS)

Zhao, Dongjie; Jiang, Jian; Li, Deyi; Zhang, Haisu; Chen, Guisheng

2011-12-01

Aiming at the problem of social communication network evolution, first, topology potential is introduced to measure the local influence among nodes in networks. Second, from the perspective of topology potential distribution the method of network evolution description based on topology potential distribution is presented, which takes the artificial intelligence with uncertainty as basic theory and local influence among nodes as essentiality. Then, a social communication network is constructed by enron email dataset, the method presented is used to analyze the characteristic of the social communication network evolution and some useful conclusions are got, implying that the method is effective, which shows that topology potential distribution can effectively describe the characteristic of sociology and detect the local changes in social communication network.

WindTalker: A P2P-Based Low-Latency Anonymous Communication Network

NASA Astrophysics Data System (ADS)

Zhang, Jia; Duan, Haixin; Liu, Wu; Wu, Jianping

Compared with traditional static anonymous communication networks, the P2P architecture can provide higher anonymity in communication. However, the P2P architecture also leads to more challenges, such as route, stability, trust and so on. In this paper, we present WindTalker, a P2P-based low-latency anonymous communication network. It is a pure decentralized mix network and can provide low-latency services which help users hide their real identity in communication. In order to ensure stability and reliability, WindTalker imports “seed nodes” to help a peer join in the P2P network and the peer nodes can use gossip-based protocol to exchange active information. Moreover, WindTalker uses layer encryption to ensure the information of relayed messages cannot be leaked. In addition, malicious nodes in the network are the major threat to anonymity of P2P anonymous communication, so WindTalker imports a trust mechanism which can help the P2P network exclude malicious nodes and optimize the strategy of peer discovery, tunnel construction, and relaying etc. in anonymous communications. We deploy peer nodes of WindTalker in our campus network to test reliability and analyze anonymity in theory. The network measurement and simulation analysis shows that WindTalker can provide low-latency and reliable anonymous communication services.

Expected number of quantum channels in quantum networks.

PubMed

Chen, Xi; Wang, He-Ming; Ji, Dan-Tong; Mu, Liang-Zhu; Fan, Heng

2015-07-15

Quantum communication between nodes in quantum networks plays an important role in quantum information processing. Here, we proposed the use of the expected number of quantum channels as a measure of the efficiency of quantum communication for quantum networks. This measure quantified the amount of quantum information that can be teleported between nodes in a quantum network, which differs from classical case in that the quantum channels will be consumed if teleportation is performed. We further demonstrated that the expected number of quantum channels represents local correlations depicted by effective circles. Significantly, capacity of quantum communication of quantum networks quantified by ENQC is independent of distance for the communicating nodes, if the effective circles of communication nodes are not overlapped. The expected number of quantum channels can be enhanced through transformations of the lattice configurations of quantum networks via entanglement swapping. Our results can shed lights on the study of quantum communication in quantum networks.

Expected number of quantum channels in quantum networks

PubMed Central

Chen, Xi; Wang, He-Ming; Ji, Dan-Tong; Mu, Liang-Zhu; Fan, Heng

2015-01-01

Quantum communication between nodes in quantum networks plays an important role in quantum information processing. Here, we proposed the use of the expected number of quantum channels as a measure of the efficiency of quantum communication for quantum networks. This measure quantified the amount of quantum information that can be teleported between nodes in a quantum network, which differs from classical case in that the quantum channels will be consumed if teleportation is performed. We further demonstrated that the expected number of quantum channels represents local correlations depicted by effective circles. Significantly, capacity of quantum communication of quantum networks quantified by ENQC is independent of distance for the communicating nodes, if the effective circles of communication nodes are not overlapped. The expected number of quantum channels can be enhanced through transformations of the lattice configurations of quantum networks via entanglement swapping. Our results can shed lights on the study of quantum communication in quantum networks. PMID:26173556

Reconfigureable network node

DOEpatents

Vanderveen, Keith B [Tracy, CA; Talbot, Edward B [Livermore, CA; Mayer, Laurence E [Davis, CA

2008-04-08

Nodes in a network having a plurality of nodes establish communication links with other nodes using available transmission media, as the ability to establish such links becomes available and desirable. The nodes predict when existing communications links will fail, become overloaded or otherwise degrade network effectiveness and act to establish substitute or additional links before the node's ability to communicate with the other nodes on the network is adversely affected. A node stores network topology information and programmed link establishment rules and criteria. The node evaluates characteristics that predict existing links with other nodes becoming unavailable or degraded. The node then determines whether it can form a communication link with a substitute node, in order to maintain connectivity with the network. When changing its communication links, a node broadcasts that information to the network. Other nodes update their stored topology information and consider the updated topology when establishing new communications links for themselves.

Parallel processing data network of master and slave transputers controlled by a serial control network

DOEpatents

Crosetto, D.B.

1996-12-31

The present device provides for a dynamically configurable communication network having a multi-processor parallel processing system having a serial communication network and a high speed parallel communication network. The serial communication network is used to disseminate commands from a master processor to a plurality of slave processors to effect communication protocol, to control transmission of high density data among nodes and to monitor each slave processor`s status. The high speed parallel processing network is used to effect the transmission of high density data among nodes in the parallel processing system. Each node comprises a transputer, a digital signal processor, a parallel transfer controller, and two three-port memory devices. A communication switch within each node connects it to a fast parallel hardware channel through which all high density data arrives or leaves the node. 6 figs.

Parallel processing data network of master and slave transputers controlled by a serial control network

DOEpatents

Crosetto, Dario B.

1996-01-01

The present device provides for a dynamically configurable communication network having a multi-processor parallel processing system having a serial communication network and a high speed parallel communication network. The serial communication network is used to disseminate commands from a master processor (100) to a plurality of slave processors (200) to effect communication protocol, to control transmission of high density data among nodes and to monitor each slave processor's status. The high speed parallel processing network is used to effect the transmission of high density data among nodes in the parallel processing system. Each node comprises a transputer (104), a digital signal processor (114), a parallel transfer controller (106), and two three-port memory devices. A communication switch (108) within each node (100) connects it to a fast parallel hardware channel (70) through which all high density data arrives or leaves the node.

Remote quantification of phycocyanin in potable water sources through an adaptive model

NASA Astrophysics Data System (ADS)

Song, Kaishan; Li, Lin; Tedesco, Lenore P.; Li, Shuai; Hall, Bob E.; Du, Jia

2014-09-01

Cyanobacterial blooms in water supply sources in both central Indiana USA (CIN) and South Australia (SA) are a cause of great concerns for toxin production and water quality deterioration. Remote sensing provides an effective approach for quick assessment of cyanobacteria through quantification of phycocyanin (PC) concentration. In total, 363 samples spanning a large variation of optically active constituents (OACs) in CIN and SA waters were collected during 24 field surveys. Concurrently, remote sensing reflectance spectra (Rrs) were measured. A partial least squares-artificial neural network (PLS-ANN) model, artificial neural network (ANN) and three-band model (TBM) were developed or tuned by relating the Rrs with PC concentration. Our results indicate that the PLS-ANN model outperformed the ANN and TBM with both the original spectra and simulated ESA/Sentinel-3/Ocean and Land Color Instrument (OLCI) and EO-1/Hyperion spectra. The PLS-ANN model resulted in a high coefficient of determination (R2) for CIN dataset (R2 = 0.92, R: 0.3-220.7 μg/L) and SA (R2 = 0.98, R: 0.2-13.2 μg/L). In comparison, the TBM model yielded an R2 = 0.77 and 0.94 for the CIN and SA datasets, respectively; while the ANN obtained an intermediate modeling accuracy (CIN: R2 = 0.86; SA: R2 = 0.95). Applying the simulated OLCI and Hyperion aggregated datasets, the PLS-ANN model still achieved good performance (OLCI: R2 = 0.84; Hyperion: R2 = 0.90); the TBM also presented acceptable performance for PC estimations (OLCI: R2 = 0.65, Hyperion: R2 = 0.70). Based on the results, the PLS-ANN is an effective modeling approach for the quantification of PC in productive water supplies based on its effectiveness in solving the non-linearity of PC with other OACs. Furthermore, our investigation indicates that the ratio of inorganic suspended matter (ISM) to PC concentration has close relationship to modeling relative errors (CIN: R2 = 0.81; SA: R2 = 0.92), indicating that ISM concentration exert significant impact on PC estimation accuracy.

Design of real-time communication system for image recognition based colony picking instrument

NASA Astrophysics Data System (ADS)

Wang, Qun; Zhang, Rongfu; Yan, Hua; Wu, Huamin

2017-11-01

In order to aachieve autommated observatiion and pickinng of monocloonal colonies, an overall dessign and realizzation of real-time commmunication system based on High-throoughput monooclonal auto-piicking instrumment is propossed. The real-time commmunication system is commposed of PCC-PLC commuunication systtem and Centrral Control CComputer (CCC)-PLC communicatioon system. Bassed on RS232 synchronous serial communnication methood to develop a set of dedicated shoort-range commmunication prootocol betweenn the PC and PPLC. Furthermmore, the systemm uses SQL SSERVER database to rrealize the dataa interaction between PC andd CCC. Moreoover, the commmunication of CCC and PC, adopted Socket Ethernnet communicaation based on TCP/IP protoccol. TCP full-dduplex data cannnel to ensure real-time data eexchange as well as immprove system reliability andd security. We tested the commmunication syystem using sppecially develooped test software, thee test results show that the sysstem can realizze the communnication in an eefficient, safe aand stable way between PLC, PC andd CCC, keep thhe real-time conntrol to PLC annd colony inforrmation collecttion.

Communication, advice exchange and job satisfaction of nursing staff: a social network analyses of 35 long-term care units.

PubMed

van Beek, Adriana P A; Wagner, Cordula; Spreeuwenberg, Peter P M; Frijters, Dinnus H M; Ribbe, Miel W; Groenewegen, Peter P

2011-06-01

The behaviour of individuals is affected by the social networks in which they are embedded. Networks are also important for the diffusion of information and the influence of employees in organisations. Yet, at the moment little is known about the social networks of nursing staff in healthcare settings. This is the first study that investigates informal communication and advice networks of nursing staff in long-term care. We examine the structure of the networks, how they are related to the size of units and characteristics of nursing staff, and their relationship with job satisfaction. We collected social network data of 380 nursing staff of 35 units in group projects and psychogeriatric units in nursing homes and residential homes in the Netherlands. Communication and advice networks were analyzed in a social network application (UCINET), focusing on the number of contacts (density) between nursing staff on the units. We then studied the correlation between the density of networks, size of the units and characteristics of nursing staff. We used multilevel analyses to investigate the relationship between social networks and job satisfaction of nursing staff, taking characteristics of units and nursing staff into account. Both communication and advice networks were negatively related to the number of residents and the number of nursing staff of the units. Communication and advice networks were more dense when more staff worked part-time. Furthermore, density of communication networks was positively related to the age of nursing staff of the units. Multilevel analyses showed that job satisfaction differed significantly between individual staff members and units and was influenced by the number of nursing staff of the units. However, this relationship disappeared when density of communication networks was added to the model. Overall, communication and advice networks of nursing staff in long-term care are relatively dense. This fits with the high level of cooperation that is needed to provide good care to residents. Social networks are more dense in small units and are also shaped by characteristics of staff members. The results furthermore show that communication networks are important for staff's job satisfaction.

Communication, advice exchange and job satisfaction of nursing staff: a social network analyses of 35 long-term care units

PubMed Central

2011-01-01

Background The behaviour of individuals is affected by the social networks in which they are embedded. Networks are also important for the diffusion of information and the influence of employees in organisations. Yet, at the moment little is known about the social networks of nursing staff in healthcare settings. This is the first study that investigates informal communication and advice networks of nursing staff in long-term care. We examine the structure of the networks, how they are related to the size of units and characteristics of nursing staff, and their relationship with job satisfaction. Methods We collected social network data of 380 nursing staff of 35 units in group projects and psychogeriatric units in nursing homes and residential homes in the Netherlands. Communication and advice networks were analyzed in a social network application (UCINET), focusing on the number of contacts (density) between nursing staff on the units. We then studied the correlation between the density of networks, size of the units and characteristics of nursing staff. We used multilevel analyses to investigate the relationship between social networks and job satisfaction of nursing staff, taking characteristics of units and nursing staff into account. Results Both communication and advice networks were negatively related to the number of residents and the number of nursing staff of the units. Communication and advice networks were more dense when more staff worked part-time. Furthermore, density of communication networks was positively related to the age of nursing staff of the units. Multilevel analyses showed that job satisfaction differed significantly between individual staff members and units and was influenced by the number of nursing staff of the units. However, this relationship disappeared when density of communication networks was added to the model. Conclusions Overall, communication and advice networks of nursing staff in long-term care are relatively dense. This fits with the high level of cooperation that is needed to provide good care to residents. Social networks are more dense in small units and are also shaped by characteristics of staff members. The results furthermore show that communication networks are important for staff's job satisfaction. PMID:21631936

Development traumatic brain injury computer user interface for disaster area in Indonesia supported by emergency broadband access network.

PubMed

Sutiono, Agung Budi; Suwa, Hirohiko; Ohta, Toshizumi; Arifin, Muh Zafrullah; Kitamura, Yohei; Yoshida, Kazunari; Merdika, Daduk; Qiantori, Andri; Iskandar

2012-12-01

Disasters bring consequences of negative impacts on the environment and human life. One of the common cause of critical condition is traumatic brain injury (TBI), namely, epidural (EDH) and subdural hematoma (SDH), due to downfall hard things during earthquake. We proposed and analyzed the user response, namely neurosurgeon, general doctor/surgeon and nurse when they interacted with TBI computer interface. The communication systems was supported by TBI web based applications using emergency broadband access network with tethered balloon and simulated in the field trial to evaluate the coverage area. The interface consisted of demography data and multi tabs for anamnesis, treatment, follow up and teleconference interfaces. The interface allows neurosurgeon, surgeon/general doctors and nurses to entry the EDH and SDH patient's data during referring them on the emergency simulation and evaluated based on time needs and their understanding. The average time needed was obtained after simulated by Lenovo T500 notebook using mouse; 8-10 min for neurosurgeons, 12-15 min for surgeons/general doctors and 15-19 min for nurses. By using Think Pad X201 Tablet, the time needed for entry data was 5-7 min for neurosurgeon, 7-10 min for surgeons/general doctors and 12-16 min for nurses. We observed that the time difference was depending on the computer type and user literacy qualification as well as their understanding on traumatic brain injury, particularly for the nurses. In conclusion, there are five data classification for simply TBI GUI, namely, 1) demography, 2) specific anamnesis for EDH and SDH, 3) treatment action and medicine of TBI, 4) follow up data display and 5) teleneurosurgery for streaming video consultation. The type of computer, particularly tablet PC was more convenient and faster for entry data, compare to that computer mouse touched pad. Emergency broadband access network using tethered balloon is possible to be employed to cover the communications systems in disaster area.

Adapting Wireless Technology to Lighting Control and Environmental Sensing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dana Teasdale; Francis Rubinstein; Dave Watson

The high cost of retrofitting buildings with advanced lighting control systems is a barrier to adoption of this energy-saving technology. Wireless technology, however, offers a solution to mounting installation costs since it requires no additional wiring to implement. To demonstrate the feasibility of such a system, a prototype wirelessly-controlled advanced lighting system was designed and built. The system includes the following components: a wirelessly-controllable analog circuit module (ACM), a wirelessly-controllable electronic dimmable ballast, a T8 3-lamp fixture, an environmental multi-sensor, a current transducer, and control software. The ACM, dimmable ballast, multi-sensor, and current transducer were all integrated with SmartMesh{trademark} wirelessmore » mesh networking nodes, called motes, enabling wireless communication, sensor monitoring, and actuator control. Each mote-enabled device has a reliable communication path to the SmartMesh Manager, a single board computer that controls network functions and connects the wireless network to a PC running lighting control software. The ACM is capable of locally driving one or more standard 0-10 Volt electronic dimmable ballasts through relay control and a 0-10 Volt controllable output. The mote-integrated electronic dimmable ballast is designed to drive a standard 3-lamp T8 light fixture. The environmental multi-sensor measures occupancy, light level and temperature. The current transducer is used to measure the power consumed by the fixture. Control software was developed to implement advanced lighting algorithms, including daylight ramping, occupancy control, and demand response. Engineering prototypes of each component were fabricated and tested in a bench-scale system. Based on standard industry practices, a cost analysis was conducted. It is estimated that the installation cost of a wireless advanced lighting control system for a retrofit application is at least 30% lower than a comparable wired system for a typical 16,000 square-foot office building, with a payback period of less than 3 years.« less

Unruptured internal carotid-posterior communicating artery aneurysm splitting the oculomotor nerve: a case report and literature review.

PubMed

Toyota, Shingo; Taki, Takuyu; Wakayama, Akatsuki; Yoshimine, Toshiki

2014-08-01

Objective To report a rare case of unruptured internal carotid-posterior communicating artery (IC-PC) aneurysm splitting the oculomotor nerve treated by clipping and to review the previously published cases. Case Presentation A 42-year-old man suddenly presented with left oculomotor paresis. Three-dimensional digital subtraction angiography (3D DSA) demonstrated a left IC-PC aneurysm with a bulging part. During surgery, it was confirmed that the bulging part split the oculomotor nerve. After the fenestrated oculomotor nerve was dissected from the bulging part with a careful microsurgical technique, neck clipping was performed. After the operation, the symptoms of oculomotor nerve paresis disappeared within 2 weeks. Conclusions We must keep in mind the possibility of an anomaly of the oculomotor nerve, including fenestration, and careful observation and manipulation should be performed to preserve the nerve function during surgery, even though it is very rare.

Unruptured Internal Carotid-Posterior Communicating Artery Aneurysm Splitting the Oculomotor Nerve: A Case Report and Literature Review

PubMed Central

Toyota, Shingo; Taki, Takuyu; Wakayama, Akatsuki; Yoshimine, Toshiki

2014-01-01

Objective To report a rare case of unruptured internal carotid-posterior communicating artery (IC-PC) aneurysm splitting the oculomotor nerve treated by clipping and to review the previously published cases. Case Presentation A 42-year-old man suddenly presented with left oculomotor paresis. Three-dimensional digital subtraction angiography (3D DSA) demonstrated a left IC-PC aneurysm with a bulging part. During surgery, it was confirmed that the bulging part split the oculomotor nerve. After the fenestrated oculomotor nerve was dissected from the bulging part with a careful microsurgical technique, neck clipping was performed. After the operation, the symptoms of oculomotor nerve paresis disappeared within 2 weeks. Conclusions We must keep in mind the possibility of an anomaly of the oculomotor nerve, including fenestration, and careful observation and manipulation should be performed to preserve the nerve function during surgery, even though it is very rare. PMID:25083381

Jana: Confidential Communications on Social Networks

DTIC Science & Technology

2017-08-09

Report: Jana: Confidential Communications on Social Networks The views, opinions and/or findings contained in this report are those of the author(s) and...Confidential Communications on Social Networks Report Term: 0-Other Email: krish@ucr.edu Distribution Statement: 1-Approved for public release; distribution...is unlimited. Major Goals: The inability of users to communicate secretly on online social networking (OSN) platforms is a key obstacle to overcome

The Virtual Research and Extension Communication Network (VRECN): An Interactive Learning and Communication Network for Research and Extension Personnel. Concept Paper for the Food & Agriculture Organisation of the United Nations (FAO).

ERIC Educational Resources Information Center

Richardson, Don

A Virtual Research and Extension Communication Network (VRECN) is a set of networked electronic tools facilitating improvement in communication processes and information sharing among stakeholders involved in agricultural development. In developing countries, research and extension personnel within a ministry of agriculture, in consultation and…

Final Environmental Assessment for Wide Area Coverage Construct Land Mobile Network Communications Infrastructure Malmstrom Air Force Base, Montana

DTIC Science & Technology

2008-02-01

FINAL ENVIRONMENTAL ASSESSMENT February 2008 Malmstrom ® AFB WIDE AREA COVERAGE CONSTRUCT LAND MOBILE NETWORK COMMUNICATIONS INFRASTRUCTURE...Wide Area Coverage Construct Land Mobile Network Communications Infrastructure Malmstrom Air Force Base, Montana 5a. CONTRACT NUMBER 5b. GRANT...SIGNIFICANT IMPACT WIDE AREA COVERAGE CONSTRUCT LAND MOBILE NETWORK COMMUNICATIONS INFRASTRUCTURE MALMSTROM AIR FORCE BASE, MONTANA The

High-Performance Satellite/Terrestrial-Network Gateway

NASA Technical Reports Server (NTRS)

Beering, David R.

2005-01-01

A gateway has been developed to enable digital communication between (1) the high-rate receiving equipment at NASA's White Sands complex and (2) a standard terrestrial digital communication network at data rates up to 622 Mb/s. The design of this gateway can also be adapted for use in commercial Earth/satellite and digital communication networks, and in terrestrial digital communication networks that include wireless subnetworks. Gateway as used here signifies an electronic circuit that serves as an interface between two electronic communication networks so that a computer (or other terminal) on one network can communicate with a terminal on the other network. The connection between this gateway and the high-rate receiving equipment is made via a synchronous serial data interface at the emitter-coupled-logic (ECL) level. The connection between this gateway and a standard asynchronous transfer mode (ATM) terrestrial communication network is made via a standard user network interface with a synchronous optical network (SONET) connector. The gateway contains circuitry that performs the conversion between the ECL and SONET interfaces. The data rate of the SONET interface can be either 155.52 or 622.08 Mb/s. The gateway derives its clock signal from a satellite modem in the high-rate receiving equipment and, hence, is agile in the sense that it adapts to the data rate of the serial interface.

Robust Networking Architecture and Secure Communication Scheme for Heterogeneous Wireless Sensor Networks

ERIC Educational Resources Information Center

McNeal, McKenzie, III.

2012-01-01

Current networking architectures and communication protocols used for Wireless Sensor Networks (WSNs) have been designed to be energy efficient, low latency, and long network lifetime. One major issue that must be addressed is the security in data communication. Due to the limited capabilities of low cost and small sized sensor nodes, designing…

Learning and Networking: Utilization of a Primary Care Listserv by Pharmacists

PubMed Central

Trinacty, Melanie; Farrell, Barbara; Schindel, Theresa J; Sunstrum, Lisa; Dolovich, Lisa; Kennie, Natalie; Russell, Grant; Waite, Nancy

2014-01-01

Background Expanding into new types of practice, such as family health teams, presents challenges for practising pharmacists. The Primary Care Pharmacy Specialty Network (PC-PSN) was established in 2007 to support collaboration among pharmacists working in primary care. The PC-PSN offers to its members a listserv (also referred to as an electronic mailing list) jointly hosted by the Canadian Society of Hospital Pharmacists and the Canadian Pharmacists Association. Objectives: To characterize PC-PSN membership and participation in the listserv and to examine how the listserv is used by analyzing questions posted, concerns raised, and issues discussed. Methods: Qualitative content analysis was used to examine 1 year of archived PC-PSN listserv posts from the year 2010. Two coders used NVivo software to classify the content of posts. Research team members reviewed and discussed the coding reports to confirm themes emerging from the data. Results: Overall, 129 people (52.9% of the 244 listserv members registered at the end of the calendar year) posted to the listserv during the study period. These participants worked in various practice settings, with over half residing in Ontario (68/129 [52.7%]). A total of 623 posts were coded. Agreement between coders, for a sample of posts from 10 users, was acceptable (kappa = 0.78). The listserv was used to share information on a diverse set of topics, to support decision-making and acquire solutions for complex problems, and as a forum for mentorship. Conclusions: The qualitative content analysis of the PC-PSN listserv posts for the year 2010 showed that the listserv was a medium for information-sharing and for providing and receiving support, through mentorship from colleagues. Apparent learning needs included effective question-posing skills and application of evidence to individual patients. PMID:25364016

Scalable Hierarchical Network Management System for Displaying Network Information in Three Dimensions

NASA Technical Reports Server (NTRS)

George, Jude (Inventor); Schlecht, Leslie (Inventor); McCabe, James D. (Inventor); LeKashman, John Jr. (Inventor)

1998-01-01

A network management system has SNMP agents distributed at one or more sites, an input output module at each site, and a server module located at a selected site for communicating with input output modules, each of which is configured for both SNMP and HNMP communications. The server module is configured exclusively for HNMP communications, and it communicates with each input output module according to the HNMP. Non-iconified, informationally complete views are provided of network elements to aid in network management.

DNET: A communications facility for distributed heterogeneous computing

NASA Technical Reports Server (NTRS)

Tole, John; Nagappan, S.; Clayton, J.; Ruotolo, P.; Williamson, C.; Solow, H.

1989-01-01

This document describes DNET, a heterogeneous data communications networking facility. DNET allows programs operating on hosts on dissimilar networks to communicate with one another without concern for computer hardware, network protocol, or operating system differences. The overall DNET network is defined as the collection of host machines/networks on which the DNET software is operating. Each underlying network is considered a DNET 'domain'. Data communications service is provided between any two processes on any two hosts on any of the networks (domains) that may be reached via DNET. DNET provides protocol transparent, reliable, streaming data transmission between hosts (restricted, initially to DECnet and TCP/IP networks). DNET also provides variable length datagram service with optional return receipts.

Unified Approach to Modeling and Simulation of Space Communication Networks and Systems

NASA Technical Reports Server (NTRS)

Barritt, Brian; Bhasin, Kul; Eddy, Wesley; Matthews, Seth

2010-01-01

Network simulator software tools are often used to model the behaviors and interactions of applications, protocols, packets, and data links in terrestrial communication networks. Other software tools that model the physics, orbital dynamics, and RF characteristics of space systems have matured to allow for rapid, detailed analysis of space communication links. However, the absence of a unified toolset that integrates the two modeling approaches has encumbered the systems engineers tasked with the design, architecture, and analysis of complex space communication networks and systems. This paper presents the unified approach and describes the motivation, challenges, and our solution - the customization of the network simulator to integrate with astronautical analysis software tools for high-fidelity end-to-end simulation. Keywords space; communication; systems; networking; simulation; modeling; QualNet; STK; integration; space networks

Natura-alpha targets forkhead box m1 and inhibits androgen-dependent and -independent prostate cancer growth and invasion.

PubMed

Li, Yirong; Ligr, Martin; McCarron, James P; Daniels, Garrett; Zhang, David; Zhao, Xin; Ye, Fei; Wang, Jinhua; Liu, Xiaomei; Osman, Iman; Mencher, Simon K; Lepor, Hebert; Wang, Long G; Ferrari, Anna; Lee, Peng

2011-07-01

The development of new effective therapeutic agents with minimal side effects for prostate cancer (PC) treatment is much needed. Indirubin, an active molecule identified in the traditional Chinese herbal medicine-Qing Dai (Indigo naturalis), has been used to treat leukemia for decades. However, the anticancer properties of Natura-alpha, an indirubin derivative, are not well studied in solid tumors, particularly in PC. The growth kinetics and invasion ability of on human PC cell lines with or without Natura-alpha treatment were measured by cell proliferation and invasion assays. The antitumor effects of Natura-alpha were examined in nude mice tumor xenograft models, and in a patient with advanced hormone-refractory metastatic PC. Signal network proteins targeted by Natura-alpha were analyzed by using proteomic pathway array analysis (PPAA) on xenografts. Natura-alpha inhibited the growth of both androgen-dependent (LNCaP) and androgen-independent (LNCaP-AI, PC-3, and DU145) PC cells with IC(50) between 4 to 10 mmol/L, and also inhibited invasion of androgen-independent PC cells. Its antitumor effects were further evident in in vivo tumor reduction in androgen-dependent and androgen-independent nude mice tumor xenograft models and reduced tumor volume in the patient with hormone refractory metastatic PC. PPAA revealed that antiproliferative and antiinvasive activities of Natura-alpha on PC might primarily be through its downregulation of Forkhead box M1 (FOXM1) protein. Forced overexpression of FOXM1 largely reversed the inhibition of growth and invasion by Natura-alpha. Natura-alpha could serve as a novel and effective therapeutic agent for treatment of both hormone-sensitive and hormone-refractory PC with minimal side effects.

Real-Time Communication Support for Underwater Acoustic Sensor Networks †.

PubMed

Santos, Rodrigo; Orozco, Javier; Micheletto, Matias; Ochoa, Sergio F; Meseguer, Roc; Millan, Pere; Molina, And Carlos

2017-07-14

Underwater sensor networks represent an important and promising field of research due to the large diversity of underwater ubiquitous applications that can be supported by these networks, e.g., systems that deliver tsunami and oil spill warnings, or monitor submarine ecosystems. Most of these monitoring and warning systems require real-time communication in wide area networks that have a low density of nodes. The underwater communication medium involved in these networks is very harsh and imposes strong restrictions to the communication process. In this scenario, the real-time transmission of information is done mainly using acoustic signals, since the network nodes are not physically close. The features of the communication scenario and the requirements of the communication process represent major challenges for designers of both, communication protocols and monitoring and warning systems. The lack of models to represent these networks is the main stumbling block for the proliferation of underwater ubiquitous systems. This paper presents a real-time communication model for underwater acoustic sensor networks (UW-ASN) that are designed to cover wide areas with a low density of nodes, using any-to-any communication. This model is analytic, considers two solution approaches for scheduling the real-time messages, and provides a time-constraint analysis for the network performance. Using this model, the designers of protocols and underwater ubiquitous systems can quickly prototype and evaluate their solutions in an evolving way, in order to determine the best solution to the problem being addressed. The suitability of the proposal is illustrated with a case study that shows the performance of a UW-ASN under several initial conditions. This is the first analytic model for representing real-time communication in this type of network, and therefore, it opens the door for the development of underwater ubiquitous systems for several application scenarios.

Real-Time Communication Support for Underwater Acoustic Sensor Networks †

PubMed Central

Santos, Rodrigo; Orozco, Javier; Micheletto, Matias

2017-01-01

Underwater sensor networks represent an important and promising field of research due to the large diversity of underwater ubiquitous applications that can be supported by these networks, e.g., systems that deliver tsunami and oil spill warnings, or monitor submarine ecosystems. Most of these monitoring and warning systems require real-time communication in wide area networks that have a low density of nodes. The underwater communication medium involved in these networks is very harsh and imposes strong restrictions to the communication process. In this scenario, the real-time transmission of information is done mainly using acoustic signals, since the network nodes are not physically close. The features of the communication scenario and the requirements of the communication process represent major challenges for designers of both, communication protocols and monitoring and warning systems. The lack of models to represent these networks is the main stumbling block for the proliferation of underwater ubiquitous systems. This paper presents a real-time communication model for underwater acoustic sensor networks (UW-ASN) that are designed to cover wide areas with a low density of nodes, using any-to-any communication. This model is analytic, considers two solution approaches for scheduling the real-time messages, and provides a time-constraint analysis for the network performance. Using this model, the designers of protocols and underwater ubiquitous systems can quickly prototype and evaluate their solutions in an evolving way, in order to determine the best solution to the problem being addressed. The suitability of the proposal is illustrated with a case study that shows the performance of a UW-ASN under several initial conditions. This is the first analytic model for representing real-time communication in this type of network, and therefore, it opens the door for the development of underwater ubiquitous systems for several application scenarios. PMID:28708093

Computer Networks as a New Data Base.

ERIC Educational Resources Information Center

Beals, Diane E.

1992-01-01

Discusses the use of communication on computer networks as a data source for psychological, social, and linguistic research. Differences between computer-mediated communication and face-to-face communication are described, the Beginning Teacher Computer Network is discussed, and examples of network conversations are appended. (28 references) (LRW)

Communication performance analysis and comparison of two patterns for data exchange between nodes in WorldFIP fieldbus network.

PubMed

Liang, Geng; Wang, Hong; Li, Wen; Li, Dazhong

2010-10-01

Data exchange patterns between nodes in WorldFIP fieldbus network are quite important and meaningful in improving the communication performance of WorldFIP network. Based on the basic communication ways supported in WorldFIP protocol, we propose two patterns for implementation of data exchange between peer nodes over WorldFIP network. Effects on communication performance of WorldFIP network in terms of some network parameters, such as number of bytes in user's data and turn-around time, in both the proposed patterns, are analyzed at length when different network speeds are applied. Such effects with the patterns of periodic message transmission using acknowledged and non-acknowledged messages, are also studied. Communication performance in both the proposed patterns are analyzed and compared. Practical applications of the research are presented. Through the study, it can be seen that different data exchange patterns make a great difference in improving communication efficiency with different network parameters, which is quite useful and helpful in the practical design of distributed systems based on WorldFIP network. Copyright © 2010 ISA. Published by Elsevier Ltd. All rights reserved.

Chemical and Topographical Modification of Polycarbonate Surfaces through Diffusion/Photocuring Processes of Hydrogel Precursors Based on Vinylpyrrolidone.

PubMed

Gallardo, Alberto; Lujan, Noelia; Reinecke, Helmut; García, Carolina; Campo, Adolfo Del; Rodriguez-Hernandez, Juan

2017-02-21

Facile procedures capable of simultaneously conferring hydrophilicity and tailored topography to surfaces of hydrophobic supports, such as polycarbonate (PC), are very attractive but rare. In this work, we describe a simple methodology to wrinkle PC surfaces after a process of (a) contacting with a photopolymerizable vinylic solution, (b) UV curing of such solutions, and (c) detachment of the formed polymer network, upon swelling in ethanol. The influence of different parameters such as contact lag time between the PC surface and the polymerizable solution, the monomer concentration and type of solvents, as well as the cross-linking degree on the formation of wrinkles, has been studied. The dimensions of the wrinkles can be tailored to some extent by altering the different parameters. Surface chemistry has been analyzed by contact angle measurements and by confocal Raman microscopy. The results are consistent with a chemical alteration of the surface and the formation of an outer hydrogel layer, which is interpenetrated into the PC structure. A mechanism of monomer diffusion and PC swelling that produces surface instabilities and wrinkling is proposed.

Mapping Power Law Distributions in Digital Health Social Networks: Methods, Interpretations, and Practical Implications.

PubMed

van Mierlo, Trevor; Hyatt, Douglas; Ching, Andrew T

2015-06-25

Social networks are common in digital health. A new stream of research is beginning to investigate the mechanisms of digital health social networks (DHSNs), how they are structured, how they function, and how their growth can be nurtured and managed. DHSNs increase in value when additional content is added, and the structure of networks may resemble the characteristics of power laws. Power laws are contrary to traditional Gaussian averages in that they demonstrate correlated phenomena. The objective of this study is to investigate whether the distribution frequency in four DHSNs can be characterized as following a power law. A second objective is to describe the method used to determine the comparison. Data from four DHSNs—Alcohol Help Center (AHC), Depression Center (DC), Panic Center (PC), and Stop Smoking Center (SSC)—were compared to power law distributions. To assist future researchers and managers, the 5-step methodology used to analyze and compare datasets is described. All four DHSNs were found to have right-skewed distributions, indicating the data were not normally distributed. When power trend lines were added to each frequency distribution, R(2) values indicated that, to a very high degree, the variance in post frequencies can be explained by actor rank (AHC .962, DC .975, PC .969, SSC .95). Spearman correlations provided further indication of the strength and statistical significance of the relationship (AHC .987. DC .967, PC .983, SSC .993, P<.001). This is the first study to investigate power distributions across multiple DHSNs, each addressing a unique condition. Results indicate that despite vast differences in theme, content, and length of existence, DHSNs follow properties of power laws. The structure of DHSNs is important as it gives insight to researchers and managers into the nature and mechanisms of network functionality. The 5-step process undertaken to compare actor contribution patterns can be replicated in networks that are managed by other organizations, and we conjecture that patterns observed in this study could be found in other DHSNs. Future research should analyze network growth over time and examine the characteristics and survival rates of superusers.

SDN-based path hopping communication against eavesdropping attack

NASA Astrophysics Data System (ADS)

Zhang, Chuanhao; Bu, Youjun; Zhao, Zheng

2016-10-01

Network eavesdropping is one of the most popular means used by cyber attackers, which has been a severe threat to network communication security. Adversaries could capture and analyze network communication data from network nodes or links, monitor network status and steal sensitive data such as username and password etc. Traditional network usually uses static network configuration, and existing defense methods, including firewall, IDS, IPS etc., cannot prevent eavesdropping, which has no distinguishing characteristic. Network eavesdropping become silent during most of the time of the attacking process, which is why it is difficult to discover and to defend. But A successful eavesdropping attack also has its' precondition, which is the target path should be relatively stable and has enough time of duration. So, In order to resolve this problem, it has to work on the network architecture. In this paper, a path hopping communication(PHC) mechanism based on Software Define Network (SDN) was proposed to solve this problem. In PHC, Ends in communication packets as well as the routing paths were changed dynamically. Therefore, the traffic would be distributed to multiple flows and transmitted along different paths. so that Network eavesdropping attack could be prevented effectively. It was concluded that PHC was able to increase the overhead of Network eavesdropping, as well as the difficulty of communication data recovery.

Real time control “es-dawet” mixer using dasboard based on PLC and WSN

NASA Astrophysics Data System (ADS)

Siagian, Pandapotan; Hutauruk, Sindak; Kisno

2017-09-01

The aim of this study is to monitor and acquire the remote parameters like Speed control a DC Motor, IR Sensor, Temperature of pasteurize mix of ice cream, and send these real values over wireless network. A proposed system is dashboard monitoring system for PLC based system wirelessly using ZigBee protocol. To implement this a ZigBee model is connected to a programmed digital signal controller which would transmit the data to Zigbee coordinator which is connected to a PC through RS232 serial communication. Person can need only to send the reply about the process that is to be carried out and PLC will check the status of the web base sent by person and take the action according to it where wired communication is either more expensive or impossible due to physical conditions. A low cost system for measured the parameters of motor such as IR Sensor, Speed control a DC Motor by PWM and temperature with Zigbee protocol connectivity. A database is built to execute monitoring and to save the motor parameters received by radio frequency (RF) data acquisition system. Experimental results show that the proposed system is less costly, provides higher accuracy as well as safe and gives visual environment.

A PC based time domain reflectometer for space station cable fault isolation

NASA Technical Reports Server (NTRS)

Pham, Michael; McClean, Marty; Hossain, Sabbir; Vo, Peter; Kouns, Ken

1994-01-01

Significant problems are faced by astronauts on orbit in the Space Station when trying to locate electrical faults in multi-segment avionics and communication cables. These problems necessitate the development of an automated portable device that will detect and locate cable faults using the pulse-echo technique known as Time Domain Reflectometry. A breadboard time domain reflectometer (TDR) circuit board was designed and developed at the NASA-JSC. The TDR board works in conjunction with a GRiD lap-top computer to automate the fault detection and isolation process. A software program was written to automatically display the nature and location of any possible faults. The breadboard system can isolate open circuit and short circuit faults within two feet in a typical space station cable configuration. Follow-on efforts planned for 1994 will produce a compact, portable prototype Space Station TDR capable of automated switching in multi-conductor cables for high fidelity evaluation. This device has many possible commercial applications, including commercial and military aircraft avionics, cable TV, telephone, communication, information and computer network systems. This paper describes the principle of time domain reflectometry and the methodology for on-orbit avionics utility distribution system repair, utilizing the newly developed device called the Space Station Time Domain Reflectometer (SSTDR).

GP and nurses' perceptions of how after hours care for people receiving palliative care at home could be improved: a mixed methods study

PubMed Central

Tan, Heather M; O'Connor, Margaret M; Miles, Gail; Klein, Britt; Schattner, Peter

2009-01-01

Background Primary health care providers play a dominant role in the provision of palliative care (PC) in Australia but many gaps in after hours service remain. In some rural areas only 19% of people receiving palliative care achieve their goal of dying at home. This study, which builds on an earlier qualitative phase of the project, investigates the gaps in care from the perspective of general practitioners (GPs) and PC nurses. Methods Questionnaires, developed from the outcomes of the earlier phase, and containing both structured and open ended questions, were distributed through Divisions of General Practice (1 urban, 1 rural, 1 mixed) to GPs (n = 524) and through a special interest group to palliative care nurses (n = 122) in both rural and urban areas. Results Questionnaires were returned by 114 GPs (22%) and 52 nurses (43%). The majority of GPs were associated with a practice which provided some after hours services but PC was not a strong focus for most. This was reflected in low levels of PC training, limited awareness of the existence of after hours triage services in their area, and of the availability of Enhanced Primary Care (EPC) Medicare items for care planning for palliative patients. However, more than half of both nurses and GPs were aware of accessible PC resources. Factors such as poor communication and limited availability of after hours services were identified the as most likely to impact negatively on service provision. Strategies considered most likely to improve after hours services were individual patient protocols, palliative care trained respite carers and regular multidisciplinary meetings that included the GP. Conclusion While some of the identified gaps can only be met by long term funding and policy change, educational tools for use in training programs in PC for health professionals, which focus on the utilisation of EPC Medicare items in palliative care planning, the development of advance care plans and good communication between members of multidisciplinary teams, which include the GP, may enhance after hours service provision for patients receiving palliative care at home. The role of locums in after PC is an area for further research PMID:19751527

Development of a practice tool for community-based nurses: the Heart Failure Palliative Approach to Care (HeFPAC).

PubMed

Strachan, Patricia H; Joy, Cathy; Costigan, Jeannine; Carter, Nancy

2014-04-01

Patients living with advanced heart failure (HF) require a palliative approach to reduce suffering. Nurses have described significant knowledge gaps about the disease-specific palliative care (PC) needs of these patients. An intervention is required to facilitate appropriate end-of-life care for HF patients. The purpose of this study was to develop a user-friendly, evidence-informed HF-specific practice tool for community-based nurses to facilitate care and communication regarding a palliative approach to HF care. Guided by the Knowledge to Action framework, we identified key HF-specific issues related to advanced HF care provision within the context of a palliative approach to care. Informed by current evidence and subsequent iterative consultation with community-based and specialist PC and HF nurses, a pocket guide tool for community-based nurses was created. We developed the Heart Failure Palliative Approach to Care (HeFPAC) pocket guide to promote communication and a palliative approach to care for HF patients. The HeFPAC has potential to improve the quality of care and experiences for patients with advanced HF. It will be piloted in community-based practice and in a continuing education program for nurses. The HeFPAC pocket guide offers PC nurses a concise, evidence-informed and practical point-of care tool to communicate with other clinicians and patients about key HF issues that are associated with improving disease-specific HF palliative care and the quality of life of patients and their families. Pilot testing will offer insight as to its utility and potential for modification for national and international use.

78 FR 55096 - Certain Point-to-Point Network Communication Devices and Products Containing Same; Institution of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-09

... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-892] Certain Point-to-Point Network... sale within the United States after importation of certain point-to- point network communication... sale within the United States after importation of certain point-to- point network communication...

Cooperative UAV-Based Communications Backbone for Sensor Networks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, R S

2001-10-07

The objective of this project is to investigate the use of unmanned air vehicles (UAVs) as mobile, adaptive communications backbones for ground-based sensor networks. In this type of network, the UAVs provide communication connectivity to sensors that cannot communicate with each other because of terrain, distance, or other geographical constraints. In these situations, UAVs provide a vertical communication path for the sensors, thereby mitigating geographic obstacles often imposed on networks. With the proper use of UAVs, connectivity to a widely disbursed sensor network in rugged terrain is readily achieved. Our investigation has focused on networks where multiple cooperating UAVs aremore » used to form a network backbone. The advantage of using multiple UAVs to form the network backbone is parallelization of sensor connectivity. Many widely spaced or isolated sensors can be connected to the network at once using this approach. In these networks, the UAVs logically partition the sensor network into sub-networks (subnets), with one UAV assigned per subnet. Partitioning the network into subnets allows the UAVs to service sensors in parallel thereby decreasing the sensor-to-network connectivity. A UAV services sensors in its subnet by flying a route (path) through the subnet, uplinking data collected by the sensors, and forwarding the data to a ground station. An additional advantage of using multiple UAVs in the network is that they provide redundancy in the communications backbone, so that the failure of a single UAV does not necessarily imply the loss of the network.« less

The First Year of Croatian Meteor Network

NASA Astrophysics Data System (ADS)

Andreic, Zeljko; Segon, Damir

2010-08-01

The idea and a short history of Croatian Meteor Network (CMN) is described. Based on use of cheap surveillance cameras, standard PC-TV cards and old PCs, the Network allows schools, amateur societies and individuals to participate in photographic meteor patrol program. The network has a strong educational component and many cameras are located at or around teaching facilities. Data obtained by these cameras are collected and processed by the scientific team of the network. Currently 14 cameras are operable, covering a large part of the croatian sky, data gathering is fully functional, and data reduction software is in testing phase.

Fabrication and charge/energy-transfer study of 4,7-bis(4-triphenylamino)benzo- 2,1,3-thiadiazole/CuPc composite films

NASA Astrophysics Data System (ADS)

Zhu, Yuanyuan; Gu, Shuangxi; Wei, Xiao; Xue, Minzhao; Zhang, Qing; Sheng, Qiaorong; Liu, Yangang

2010-12-01

Composite films of 4,7-bis(4-triphenylamino)benzo-2,1,3-thiadiazole (TBT) and copper phthalocyanine (CuPc) are fabricated via protonation-coelectrophoretic deposition from nitromethane solutions of TBT/CuPc mixture in the presence of trifluoroacetic acid as a protonation reagent. A nanospheres-nanowires interpenetrating network structure is obtained when the molar percentage of TBT is 70%. Furthermore, the existence of TBT makes α-phased CuPc be partly transformed into the β-phase, and simultaneously, CuPc disorganizes the TBT unit cells. The blue shift on the absorption edge of TBT and the significant fluorescence quenching in the composite films indicate energy/charge transfer and donor-acceptor (D-A) heterojunction formation. Then these results are proved from another point of view: the mutual overlap of absorption and emission spectra of TBT and CuPc lead to a bidirectional Förster resonance energy transfer at the interface; the molecular energy levels calculated from the results of cyclic voltammetry theoretically determine that there exist a D-A heterojunction and charge transfer from TBT to CuPc. Finally, from the investigation of the field-induced surface photovoltage spectra, it can be concluded that this charge transfer results in efficient dissociation of the photoinduced excitons in the composite films, followed by the generation of a strong photovoltage response.

Adaptive feedback synchronisation of complex dynamical network with discrete-time communications and delayed nodes

NASA Astrophysics Data System (ADS)

Wang, Tong; Ding, Yongsheng; Zhang, Lei; Hao, Kuangrong

2016-08-01

This paper considered the synchronisation of continuous complex dynamical networks with discrete-time communications and delayed nodes. The nodes in the dynamical networks act in the continuous manner, while the communications between nodes are discrete-time; that is, they communicate with others only at discrete time instants. The communication intervals in communication period can be uncertain and variable. By using a piecewise Lyapunov-Krasovskii function to govern the characteristics of the discrete communication instants, we investigate the adaptive feedback synchronisation and a criterion is derived to guarantee the existence of the desired controllers. The globally exponential synchronisation can be achieved by the controllers under the updating laws. Finally, two numerical examples including globally coupled network and nearest-neighbour coupled networks are presented to demonstrate the validity and effectiveness of the proposed control scheme.

User Needs and Advances in Space Wireless Sensing and Communications

NASA Technical Reports Server (NTRS)

Kegege, Obadiah

2017-01-01

Decades of space exploration and technology trends for future missions show the need for new approaches in space/planetary sensor networks, observatories, internetworking, and communications/data delivery to Earth. The User Needs to be discussed in this talk includes interviews with several scientists and reviews of mission concepts for the next generation of sensors, observatories, and planetary surface missions. These observatories, sensors are envisioned to operate in extreme environments, with advanced autonomy, whereby sometimes communication to Earth is intermittent and delayed. These sensor nodes require software defined networking capabilities in order to learn and adapt to the environment, collect science data, internetwork, and communicate. Also, some user cases require the level of intelligence to manage network functions (either as a host), mobility, security, and interface data to the physical radio/optical layer. For instance, on a planetary surface, autonomous sensor nodes would create their own ad-hoc network, with some nodes handling communication capabilities between the wireless sensor networks and orbiting relay satellites. A section of this talk will cover the advances in space communication and internetworking to support future space missions. NASA's Space Communications and Navigation (SCaN) program continues to evolve with the development of optical communication, a new vision of the integrated network architecture with more capabilities, and the adoption of CCSDS space internetworking protocols. Advances in wireless communications hardware and electronics have enabled software defined networking (DVB-S2, VCM, ACM, DTN, Ad hoc, etc.) protocols for improved wireless communication and network management. Developing technologies to fulfil these user needs for wireless communications and adoption of standardized communication/internetworking protocols will be a huge benefit to future planetary missions, space observatories, and manned missions to other planets.

Technology forecasting for space communication. [analysis of systems for application to Spacecraft Data and Tracking Network

NASA Technical Reports Server (NTRS)

1973-01-01

A study was conducted to determine techniques for application to space communication. The subjects considered are as follows: (1) optical communication systems, (2) laser communications for data acquisition networks, (3) spacecraft data rate requirements, (4) telemetry, command, and data handling, (5) spacecraft tracking and data network antenna and preamplifier cost tradeoff study, and (6) spacecraft communication terminal evaluation.

A Skilful Marine Sclerochronological Network Based Reconstruction of North Atlantic Subpolar Gyre Dynamics

NASA Astrophysics Data System (ADS)

Reynolds, D.; Hall, I. R.; Slater, S. M.; Scourse, J. D.; Wanamaker, A. D.; Halloran, P. R.; Garry, F. K.

2017-12-01

Spatial network analyses of precisely dated, and annually resolved, tree-ring proxy records have facilitated robust reconstructions of past atmospheric climate variability and the associated mechanisms and forcings that drive it. In contrast, a lack of similarly dated marine archives has constrained the use of such techniques in the marine realm, despite the potential for developing a more robust understanding of the role basin scale ocean dynamics play in the global climate system. Here we show that a spatial network of marine molluscan sclerochronological oxygen isotope (δ18Oshell) series spanning the North Atlantic region provides a skilful reconstruction of basin scale North Atlantic sea surface temperatures (SSTs). Our analyses demonstrate that the composite marine series (referred to as δ18Oproxy_PC1) is significantly sensitive to inter-annual variability in North Atlantic SSTs (R=-0.61 P<0.01) and surface air temperatures (SATs; R=-0.67, P<0.01) over the 20th century. Subpolar gyre (SPG) SSTs dominates variability in the δ18Oproxy_PC1 series at sub-centennial frequencies (R=-0.51, P<0.01). Comparison of the δ18Oproxy_PC1 series against variability in the strength of the European Slope Current and maximum North Atlantic meridional overturning circulation derived from numeric climate models (CMIP5), indicates that variability in the SPG region, associated with the strength of the surface currents of the North Atlantic, are playing a significant role in shaping the multi-decadal scale SST variability over the industrial era. These analyses demonstrate that spatial networks developed from sclerochronological archives can provide powerful baseline archives of past ocean variability that can facilitate the development of a quantitative understanding for the role the oceans play in the global climate systems and constraining uncertainties in numeric climate models.

Influence of Telecommunication Modality, Internet Transmission Quality, and Accessories on Speech Perception in Cochlear Implant Users

PubMed Central

Koller, Roger; Guignard, Jérémie; Caversaccio, Marco; Kompis, Martin; Senn, Pascal

2017-01-01

Background Telecommunication is limited or even impossible for more than one-thirds of all cochlear implant (CI) users. Objective We sought therefore to study the impact of voice quality on speech perception with voice over Internet protocol (VoIP) under real and adverse network conditions. Methods Telephone speech perception was assessed in 19 CI users (15-69 years, average 42 years), using the German HSM (Hochmair-Schulz-Moser) sentence test comparing Skype and conventional telephone (public switched telephone networks, PSTN) transmission using a personal computer (PC) and a digital enhanced cordless telecommunications (DECT) telephone dual device. Five different Internet transmission quality modes and four accessories (PC speakers, headphones, 3.5 mm jack audio cable, and induction loop) were compared. As a secondary outcome, the subjective perceived voice quality was assessed using the mean opinion score (MOS). Results Speech telephone perception was significantly better (median 91.6%, P<.001) with Skype compared with PSTN (median 42.5%) under optimal conditions. Skype calls under adverse network conditions (data packet loss > 15%) were not superior to conventional telephony. In addition, there were no significant differences between the tested accessories (P>.05) using a PC. Coupling a Skype DECT phone device with an audio cable to the CI, however, resulted in higher speech perception (median 65%) and subjective MOS scores (3.2) than using PSTN (median 7.5%, P<.001). Conclusions Skype calls significantly improve speech perception for CI users compared with conventional telephony under real network conditions. Listening accessories do not further improve listening experience. Current Skype DECT telephone devices do not fully offer technical advantages in voice quality. PMID:28438727

Influence of Telecommunication Modality, Internet Transmission Quality, and Accessories on Speech Perception in Cochlear Implant Users.

PubMed

Mantokoudis, Georgios; Koller, Roger; Guignard, Jérémie; Caversaccio, Marco; Kompis, Martin; Senn, Pascal

2017-04-24

Telecommunication is limited or even impossible for more than one-thirds of all cochlear implant (CI) users. We sought therefore to study the impact of voice quality on speech perception with voice over Internet protocol (VoIP) under real and adverse network conditions. Telephone speech perception was assessed in 19 CI users (15-69 years, average 42 years), using the German HSM (Hochmair-Schulz-Moser) sentence test comparing Skype and conventional telephone (public switched telephone networks, PSTN) transmission using a personal computer (PC) and a digital enhanced cordless telecommunications (DECT) telephone dual device. Five different Internet transmission quality modes and four accessories (PC speakers, headphones, 3.5 mm jack audio cable, and induction loop) were compared. As a secondary outcome, the subjective perceived voice quality was assessed using the mean opinion score (MOS). Speech telephone perception was significantly better (median 91.6%, P<.001) with Skype compared with PSTN (median 42.5%) under optimal conditions. Skype calls under adverse network conditions (data packet loss > 15%) were not superior to conventional telephony. In addition, there were no significant differences between the tested accessories (P>.05) using a PC. Coupling a Skype DECT phone device with an audio cable to the CI, however, resulted in higher speech perception (median 65%) and subjective MOS scores (3.2) than using PSTN (median 7.5%, P<.001). Skype calls significantly improve speech perception for CI users compared with conventional telephony under real network conditions. Listening accessories do not further improve listening experience. Current Skype DECT telephone devices do not fully offer technical advantages in voice quality. ©Georgios Mantokoudis, Roger Koller, Jérémie Guignard, Marco Caversaccio, Martin Kompis, Pascal Senn. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 24.04.2017.

A cross-domain communication resource scheduling method for grid-enabled communication networks

NASA Astrophysics Data System (ADS)

Zheng, Xiangquan; Wen, Xiang; Zhang, Yongding

2011-10-01

To support a wide range of different grid applications in environments where various heterogeneous communication networks coexist, it is important to enable advanced capabilities in on-demand and dynamical integration and efficient co-share with cross-domain heterogeneous communication resource, thus providing communication services which are impossible for single communication resource to afford. Based on plug-and-play co-share and soft integration with communication resource, Grid-enabled communication network is flexibly built up to provide on-demand communication services for gird applications with various requirements on quality of service. Based on the analysis of joint job and communication resource scheduling in grid-enabled communication networks (GECN), this paper presents a cross multi-domain communication resource cooperatively scheduling method and describes the main processes such as traffic requirement resolution for communication services, cross multi-domain negotiation on communication resource, on-demand communication resource scheduling, and so on. The presented method is to afford communication service capability to cross-domain traffic delivery in GECNs. Further research work towards validation and implement of the presented method is pointed out at last.

A vision of network-centric military communications

NASA Astrophysics Data System (ADS)

Conklin, Ross, Jr.; Burbank, Jack; Nichols, Robert, Jr.

2005-05-01

This paper presents a vision for a future capability-based military communications system that considers user requirements. Historically, the military has developed and fielded many specialized communications systems. While these systems solved immediate communications problems, they were not designed to operate with other systems. As information has become more important to the execution of war, the "stove-pipe" nature of the communications systems deployed by the military is no longer acceptable. Realizing this, the military has begun the transformation of communications to a network-centric communications paradigm. However, the specialized communications systems were developed in response to the widely varying environments related to military communications. These environments, and the necessity for effective communications within these environments, do not disappear under the network-centric paradigm. In fact, network-centric communications allows for one message to cross many of these environments by transiting multiple networks. The military would also like one communications approach that is capable of working well in multiple environments. This paper presents preliminary work on the creation of a framework that allows for a reconfigurable device that is capable of adapting to the physical and network environments. The framework returns to the Open Systems Interconnect (OSI) architecture with the addition of a standardized intra-layer control interface for control information exchange, a standardized data interface and a proposed device architecture based on the software radio.

A new way to improve the robustness of complex communication networks by allocating redundancy links

NASA Astrophysics Data System (ADS)

Shi, Chunhui; Peng, Yunfeng; Zhuo, Yue; Tang, Jieying; Long, Keping

2012-03-01

We investigate the robustness of complex communication networks on allocating redundancy links. The protecting key nodes (PKN) strategy is proposed to improve the robustness of complex communication networks against intentional attack. Our numerical simulations show that allocating a few redundant links among key nodes using the PKN strategy will significantly increase the robustness of scale-free complex networks. We have also theoretically proved and demonstrated the effectiveness of the PKN strategy. We expect that our work will help achieve a better understanding of communication networks.

High-performance software-only H.261 video compression on PC

NASA Astrophysics Data System (ADS)

Kasperovich, Leonid

1996-03-01

This paper describes an implementation of a software H.261 codec for PC, that takes an advantage of the fast computational algorithms for DCT-based video compression, which have been presented by the author at the February's 1995 SPIE/IS&T meeting. The motivation for developing the H.261 prototype system is to demonstrate a feasibility of real time software- only videoconferencing solution to operate across a wide range of network bandwidth, frame rate, and resolution of the input video. As the bandwidths of current network technology will be increased, the higher frame rate and resolution of video to be transmitted is allowed, that requires, in turn, a software codec to be able to compress pictures of CIF (352 X 288) resolution at up to 30 frame/sec. Running on Pentium 133 MHz PC the codec presented is capable to compress video in CIF format at 21 - 23 frame/sec. This result is comparable to the known hardware-based H.261 solutions, but it doesn't require any specific hardware. The methods to achieve high performance, the program optimization technique for Pentium microprocessor along with the performance profile, showing the actual contribution of the different encoding/decoding stages to the overall computational process, are presented.

Do learning collaboratives strengthen communication? A comparison of organizational team communication networks over time.

PubMed

Bunger, Alicia C; Lengnick-Hall, Rebecca

Collaborative learning models were designed to support quality improvements, such as innovation implementation by promoting communication within organizational teams. Yet the effect of collaborative learning approaches on organizational team communication during implementation is untested. The aim of this study was to explore change in communication patterns within teams from children's mental health organizations during a year-long learning collaborative focused on implementing a new treatment. We adopt a social network perspective to examine intraorganizational communication within each team and assess change in (a) the frequency of communication among team members, (b) communication across organizational hierarchies, and (c) the overall structure of team communication networks. A pretest-posttest design compared communication among 135 participants from 21 organizational teams at the start and end of a learning collaborative. At both time points, participants were asked to list the members of their team and rate the frequency of communication with each along a 7-point Likert scale. Several individual, pair-wise, and team level communication network metrics were calculated and compared over time. At the individual level, participants reported communicating with more team members by the end of the learning collaborative. Cross-hierarchical communication did not change. At the team level, these changes manifested differently depending on team size. In large teams, communication frequency increased, and networks grew denser and slightly less centralized. In small teams, communication frequency declined, growing more sparse and centralized. Results suggest that team communication patterns change minimally but evolve differently depending on size. Learning collaboratives may be more helpful for enhancing communication among larger teams; thus, managers might consider selecting and sending larger staff teams to learning collaboratives. This study highlights key future research directions that can disentangle the relationship between learning collaboratives and team networks.

Advanced information society(5)

NASA Astrophysics Data System (ADS)

Tanizawa, Ippei

Based on the advancement of information network technology information communication forms informationalized society giving significant impact on business activities and life style in it. The information network has been backed up technologically by development of computer technology and has got great contribution by enhanced computer technology and communication equipments. Information is transferred by digital and analog methods. Technical development which has brought out multifunctioned modems of communication equipments in analog mode, and construction of advanced information communication network which has come out by joint work of computer and communication under digital technique, are described. The trend in institutional matter and standardization of electrical communication is also described showing some examples of value-added network (VAN).

Molecular dynamics studies of interpenetrating polymer networks for actuator devices

NASA Astrophysics Data System (ADS)

Brandell, Daniel; Kasemägi, Heiki; Citérin, Johann; Vidal, Frédéric; Chevrot, Claude; Aabloo, Alvo

2008-03-01

Molecular Dynamics (MD) techniques have been used to study the structure and dynamics of a model system of an interpenetrating polymer (IPN) network for actuator devices. The systems simulated were generated using a Monte Carlo-approach, and consisted of poly(ethylene oxide) (PEO) and poly(butadiene) (PB) in a 80-20 percent weight ratio immersed into propylene carbonate (PC) solutions of LiClO 4. The total polymer content was 32%, in order to model experimental conditions. The dependence of LiClO 4 concentration in PC has been studied by studying five different concentrations: 0.25, 0.5, 0.75, 1.0 and 1.25 M. After equilibration, local structural properties and dynamical features such as phase separation, coordination, cluster stability and ion conductivity were studied. In an effort to study the conduction processes more carefully, external electric fields of 1×10 6 V/m and 5×10 6 V/m has been applied to the simulation boxes. A clear relationship between the degree of local phase separation and ion mobility is established. It is also shown that although the ion pairing increases with concentration, there are still significantly more potential charge carriers in the higher concentrated systems, while concentrations around 0.5-0.75 M of LiClO 4 in PC seem to be favorable in terms of ion mobility. Furthermore, the anions exhibit higher conductivity than the cations, and there are tendencies to solvent drag from the PC molecules.

Distributed numerical controllers

NASA Astrophysics Data System (ADS)

Orban, Peter E.

2001-12-01

While the basic principles of Numerical Controllers (NC) have not changed much during the years, the implementation of NCs' has changed tremendously. NC equipment has evolved from yesterday's hard-wired specialty control apparatus to today's graphics intensive, networked, increasingly PC based open systems, controlling a wide variety of industrial equipment with positioning needs. One of the newest trends in NC technology is the distributed implementation of the controllers. Distributed implementation promises to offer robustness, lower implementation costs, and a scalable architecture. Historically partitioning has been done along the hierarchical levels, moving individual modules into self contained units. The paper discusses various NC architectures, the underlying technology for distributed implementation, and relevant design issues. First the functional requirements of individual NC modules are analyzed. Module functionality, cycle times, and data requirements are examined. Next the infrastructure for distributed node implementation is reviewed. Various communication protocols and distributed real-time operating system issues are investigated and compared. Finally, a different, vertical system partitioning, offering true scalability and reconfigurability is presented.

Operational Space Weather Products at IPS

NASA Astrophysics Data System (ADS)

Neudegg, D.; Steward, G.; Marshall, R.; Terkildsen, M.; Kennewell, J.; Patterson, G.; Panwar, R.

2008-12-01

IPS Radio and Space Services operates an extensive network (IPSNET) of monitoring stations and observatories within the Australasian and Antarctic regions to gather information on the space environment. This includes ionosondes, magnetometers, GPS-ISM, oblique HF sounding, riometers, and solar radio and optical telescopes. IPS exchanges this information with similar organisations world-wide. The Regional Warning Centre (RWC) is the Australian Space Forecast Centre (ASFC) and it utilizes this data to provide products and services to support customer operations. A wide range of customers use IPS services including; defence force and emergency services using HF radio communications and surveillance systems, organisations involved in geophysical exploration and pipeline cathodic protection, GPS users in aviation. Subscriptions to the alerts, warnings, forecasts and reports regarding the solar, geophysical and ionospheric conditions are distributed by email and Special Message Service (SMS). IPS also develops and markets widely used PC software prediction tools for HF radio skywave and surface wave (ASAPS/GWPS) and provides consultancy services for system planning.

Web-based radiology: a future to be created.

PubMed

Canadè, Adolfo; Palladino, Francesco; Pitzalis, Gianluca; Campioni, Paolo; Marano, Pasquale

2003-01-01

The impact of Internet on Medicine and Surgery is certainly remarkable, however the influence it had on Diagnostic Imaging was even stronger. The standardization of digital images acquired by the different medical imaging equipment has further facilitated the diffusion, transmission and communication in radiology within hospitals as well as on WEB. Radiology departments are bound to become "filmless" and with the present "tablet PC" radiological images will be directly transferred to the patient's bed in the relative electronic patient report. For radiology, interactive education could be envisaged with a tutor who guides the student(s) through the network. The Internet is an inexhaustible source of radiologic educational and information material with a number of sites of clinical cases, tutorial and teaching files, journals and magisterial lectures on-line. In a near future, the Internet could be applied in the simulation of clinicoradiologic cases or in applications of artificial intelligence with expert systems to support the solution of most complex cases.

[The endoscopic operating room OR 1].

PubMed

Dubuisson, J B; Chapron, C

2003-04-01

During the last few years, the development of surgical laparoscopy has been the major turning point, and the most important progress in the field of surgery. The specific installation requirements of surgical laparoscopy, as well as the technological progress proper to this surgical technique, justify the need of a new organization of the operating theatre. The new operating room OR 1 is especially designed to fit and satisfy the requirements of a modern operating theatre, where surgical laparoscopy plays a major role. The organization and the design of this new operating room (OR 1) rely on 2 main concepts: architectural, and computerized, through 2 PC systems SCB and AIDA. The main objectives of this new concept are: allowing the surgeon to control and command all the functions and the instruments, as well as the lighting of the room and the operating field; managing the surgical data and images required for medical files; establishing a communication network either from the inside or outside the sterile zone.

FASTER - A tool for DSN forecasting and scheduling

NASA Technical Reports Server (NTRS)

Werntz, David; Loyola, Steven; Zendejas, Silvino

1993-01-01

FASTER (Forecasting And Scheduling Tool for Earth-based Resources) is a suite of tools designed for forecasting and scheduling JPL's Deep Space Network (DSN). The DSN is a set of antennas and other associated resources that must be scheduled for satellite communications, astronomy, maintenance, and testing. FASTER consists of MS-Windows based programs that replace two existing programs (RALPH and PC4CAST). FASTER was designed to be more flexible, maintainable, and user friendly. FASTER makes heavy use of commercial software to allow for customization by users. FASTER implements scheduling as a two pass process: the first pass calculates a predictive profile of resource utilization; the second pass uses this information to calculate a cost function used in a dynamic programming optimization step. This information allows the scheduler to 'look ahead' at activities that are not as yet scheduled. FASTER has succeeded in allowing wider access to data and tools, reducing the amount of effort expended and increasing the quality of analysis.

A high-rate PCI-based telemetry processor system

NASA Astrophysics Data System (ADS)

Turri, R.

2002-07-01

The high performances reached by the Satellite on-board telemetry generation and transmission, as consequently, will impose the design of ground facilities with higher processing capabilities at low cost to allow a good diffusion of these ground station. The equipment normally used are based on complex, proprietary bus and computing architectures that prevent the systems from exploiting the continuous and rapid increasing in computing power available on market. The PCI bus systems now allow processing of high-rate data streams in a standard PC-system. At the same time the Windows NT operating system supports multitasking and symmetric multiprocessing, giving the capability to process high data rate signals. In addition, high-speed networking, 64 bit PCI-bus technologies and the increase in processor power and software, allow creating a system based on COTS products (which in future may be easily and inexpensively upgraded). In the frame of EUCLID RTP 9.8 project, a specific work element was dedicated to develop the architecture of a system able to acquire telemetry data of up to 600 Mbps. Laben S.p.A - a Finmeccanica Company -, entrusted of this work, has designed a PCI-based telemetry system making possible the communication between a satellite down-link and a wide area network at the required rate.

A system for ubiquitous fall monitoring at home via a wireless sensor network.

PubMed

Fernandez-Luque, Francisco J; Zapata, Juan; Ruiz, Ramon

2010-01-01

Accidental falls of our elderly, and physical injuries resulting, represent a major health and economic. Falls are the most common causes of serious injuries and a major health threats in the stratum of older population. Early detection of a fall is a key factor when trying to provide adequate care to the elderly person who has suffered an accident at home. In this paper, we present a support system for detecting falls of an elder person by a static wireless nonintrusive sensorial infrastructure based on heterogenous sensor nodes. This previous infrastructure, named AID (Alarm Intelligent Device), is an AAL (Ambient Assisted Living) system that allows to infer a potential fall. We have developed, different to other contributions, a specific low-power multi-hop network consists of nodes (Motes) that wirelessly communicate to each other and are capable of hopping radio messages to a base station where they are passed to a PC (or other possible client). The goal of this project is 1) to provide alerts to caregivers in the event of an accident, acute illness or strange (possibly dangerous) activities, and 2) to enable that authorized and authenticated caregivers by means of a itinerant wearable mote can be inserted into mesh and interact with it. In this paper, we describe an ubiquitous assistential monitoring system at home.

Real-time distributed video coding for 1K-pixel visual sensor networks

NASA Astrophysics Data System (ADS)

Hanca, Jan; Deligiannis, Nikos; Munteanu, Adrian

2016-07-01

Many applications in visual sensor networks (VSNs) demand the low-cost wireless transmission of video data. In this context, distributed video coding (DVC) has proven its potential to achieve state-of-the-art compression performance while maintaining low computational complexity of the encoder. Despite their proven capabilities, current DVC solutions overlook hardware constraints, and this renders them unsuitable for practical implementations. This paper introduces a DVC architecture that offers highly efficient wireless communication in real-world VSNs. The design takes into account the severe computational and memory constraints imposed by practical implementations on low-resolution visual sensors. We study performance-complexity trade-offs for feedback-channel removal, propose learning-based techniques for rate allocation, and investigate various simplifications of side information generation yielding real-time decoding. The proposed system is evaluated against H.264/AVC intra, Motion-JPEG, and our previously designed DVC prototype for low-resolution visual sensors. Extensive experimental results on various data show significant improvements in multiple configurations. The proposed encoder achieves real-time performance on a 1k-pixel visual sensor mote. Real-time decoding is performed on a Raspberry Pi single-board computer or a low-end notebook PC. To the best of our knowledge, the proposed codec is the first practical DVC deployment on low-resolution VSNs.

Cholinergic and perfusion brain networks in Parkinson disease dementia.

PubMed

Colloby, Sean J; McKeith, Ian G; Burn, David J; Wyper, David J; O'Brien, John T; Taylor, John-Paul

2016-07-12

To investigate muscarinic M1/M4 cholinergic networks in Parkinson disease dementia (PDD) and their association with changes in Mini-Mental State Examination (MMSE) after 12 weeks of treatment with donepezil. Forty-nine participants (25 PDD and 24 elderly controls) underwent (123)I-QNB and (99m)Tc-exametazime SPECT scanning. We implemented voxel principal components (PC) analysis, producing a series of PC images of patterns of interrelated voxels across individuals. Linear regression analyses derived specific M1/M4 and perfusion spatial covariance patterns (SCPs). We found an M1/M4 SCP of relative decreased binding in basal forebrain, temporal, striatum, insula, and anterior cingulate (F1,47 = 31.9, p < 0.001) in cholinesterase inhibitor-naive patients with PDD, implicating limbic-paralimbic and salience cholinergic networks. The corresponding regional cerebral blood flow SCP showed relative decreased uptake in temporoparietal and prefrontal areas (F1,47 = 177.5, p < 0.001) and nodes of the frontoparietal and default mode networks (DMN). The M1/M4 pattern that correlated with an improvement in MMSE (r = 0.58, p = 0.005) revealed relatively preserved/increased pre/medial/orbitofrontal, parietal, and posterior cingulate areas coinciding with the DMN and frontoparietal networks. Dysfunctional limbic-paralimbic and salience cholinergic networks were associated with PDD. Established cholinergic maintenance of the DMN and frontoparietal networks may be prerequisite for cognitive remediation following cholinergic treatment in this condition. © 2016 American Academy of Neurology.

Cholinergic and perfusion brain networks in Parkinson disease dementia

PubMed Central

McKeith, Ian G.; Burn, David J.; Wyper, David J.; O'Brien, John T.; Taylor, John-Paul

2016-01-01

Objective: To investigate muscarinic M1/M4 cholinergic networks in Parkinson disease dementia (PDD) and their association with changes in Mini-Mental State Examination (MMSE) after 12 weeks of treatment with donepezil. Methods: Forty-nine participants (25 PDD and 24 elderly controls) underwent 123I-QNB and 99mTc-exametazime SPECT scanning. We implemented voxel principal components (PC) analysis, producing a series of PC images of patterns of interrelated voxels across individuals. Linear regression analyses derived specific M1/M4 and perfusion spatial covariance patterns (SCPs). Results: We found an M1/M4 SCP of relative decreased binding in basal forebrain, temporal, striatum, insula, and anterior cingulate (F1,47 = 31.9, p < 0.001) in cholinesterase inhibitor–naive patients with PDD, implicating limbic-paralimbic and salience cholinergic networks. The corresponding regional cerebral blood flow SCP showed relative decreased uptake in temporoparietal and prefrontal areas (F1,47 = 177.5, p < 0.001) and nodes of the frontoparietal and default mode networks (DMN). The M1/M4 pattern that correlated with an improvement in MMSE (r = 0.58, p = 0.005) revealed relatively preserved/increased pre/medial/orbitofrontal, parietal, and posterior cingulate areas coinciding with the DMN and frontoparietal networks. Conclusion: Dysfunctional limbic-paralimbic and salience cholinergic networks were associated with PDD. Established cholinergic maintenance of the DMN and frontoparietal networks may be prerequisite for cognitive remediation following cholinergic treatment in this condition. PMID:27306636

MILCOM '85 - Military Communications Conference, Boston, MA, October 20-23, 1985, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

The present conference on the development status of communications systems in the context of electronic warfare gives attention to topics in spread spectrum code acquisition, digital speech technology, fiber-optics communications, free space optical communications, the networking of HF systems, and applications and evaluation methods for digital speech. Also treated are issues in local area network system design, coding techniques and applications, technology applications for HF systems, receiver technologies, software development status, channel simultion/prediction methods, C3 networking spread spectrum networks, the improvement of communication efficiency and reliability through technical control methods, mobile radio systems, and adaptive antenna arrays. Finally, communications system cost analyses, spread spectrum performance, voice and image coding, switched networks, and microwave GaAs ICs, are considered.

Dual Purpose Simulation: New Data Link Test and Comparison with VDL-2

NASA Technical Reports Server (NTRS)

Robinson, Daryl C.

2002-01-01

While the results of this paper are similar to those of previous research, in this paper technical difficulties present there are eliminated, producing better results, enabling one to more readily see the benefits of Prioritized CSMA (PCSMA). A new analysis section also helps to generalize this research so that it is not limited to exploration of the new concept of PCSMA. Commercially available network simulation software, OPNET version 7.0, simulations are presented involving an important application of the Aeronautical Telecommunications Network (A TN), Controller Pilot Data Link Communications (CPDLC) over the Very High Frequency Data Link Mode 2 (VDL-2). Communication is modeled for essentially all incoming and outgoing nonstop air traffic for just three United States cities: Cleveland, Cincinnati, and Detroit. The simulation involves 111 Air Traffic Control (ATC) ground stations, 32 airports distributed throughout the U.S., which are either sources or destinations for the air traffic landing or departing from the three cities, and also 1,235 equally equipped aircraft- taking off, flying realistic free- flight trajectories, and landing in a 24-hr period. Collision-less PCSMA is successfully tested and compared with the traditional CSMA typically associated with VDL-2. The performance measures include latency, throughput, and packet loss. As expected, PCSMA is much quicker and more efficient than traditional CSMA. These simulation results show the potency of PC SMA for implementing low latency, high throughput and efficient connectivity. Moreover, since PCSMA out performs traditional CSMA, by simulating with it, we can determine the limits of performance beyond which traditional CSMA may not pass. We are testing a new and better data link that could replace CSMA with relative ease. Work is underway to drastically expand the number of flights to make the simulation more representative of the National Aerospace System.

The storage capacity of Potts models for semantic memory retrieval

NASA Astrophysics Data System (ADS)

Kropff, Emilio; Treves, Alessandro

2005-08-01

We introduce and analyse a minimal network model of semantic memory in the human brain. The model is a global associative memory structured as a collection of N local modules, each coding a feature, which can take S possible values, with a global sparseness a (the average fraction of features describing a concept). We show that, under optimal conditions, the number cM of modules connected on average to a module can range widely between very sparse connectivity (high dilution, c_{M}/N\\to 0 ) and full connectivity (c_{M}\\to N ), maintaining a global network storage capacity (the maximum number pc of stored and retrievable concepts) that scales like pc~cMS2/a, with logarithmic corrections consistent with the constraint that each synapse may store up to a fraction of a bit.

A Practical Application Combining Wireless Sensor Networks and Internet of Things: Safety Management System for Tower Crane Groups

PubMed Central

Zhong, Dexing; Lv, Hongqiang; Han, Jiuqiang; Wei, Quanrui

2014-01-01

The so-called Internet of Things (IoT) has attracted increasing attention in the field of computer and information science. In this paper, a specific application of IoT, named Safety Management System for Tower Crane Groups (SMS-TC), is proposed for use in the construction industry field. The operating status of each tower crane was detected by a set of customized sensors, including horizontal and vertical position sensors for the trolley, angle sensors for the jib and load, tilt and wind speed sensors for the tower body. The sensor data is collected and processed by the Tower Crane Safety Terminal Equipment (TC-STE) installed in the driver's operating room. Wireless communication between each TC-STE and the Local Monitoring Terminal (LMT) at the ground worksite were fulfilled through a Zigbee wireless network. LMT can share the status information of the whole group with each TC-STE, while the LMT records the real-time data and reports it to the Remote Supervision Platform (RSP) through General Packet Radio Service (GPRS). Based on the global status data of the whole group, an anti-collision algorithm was executed in each TC-STE to ensure the safety of each tower crane during construction. Remote supervision can be fulfilled using our client software installed on a personal computer (PC) or smartphone. SMS-TC could be considered as a promising practical application that combines a Wireless Sensor Network with the Internet of Things. PMID:25196106

A practical application combining wireless sensor networks and Internet of Things: Safety Management System for Tower Crane Groups.

PubMed

Zhong, Dexing; Lv, Hongqiang; Han, Jiuqiang; Wei, Quanrui

2014-07-30

The so-called Internet of Things (IoT) has attracted increasing attention in the field of computer and information science. In this paper, a specific application of IoT, named Safety Management System for Tower Crane Groups (SMS-TC), is proposed for use in the construction industry field. The operating status of each tower crane was detected by a set of customized sensors, including horizontal and vertical position sensors for the trolley, angle sensors for the jib and load, tilt and wind speed sensors for the tower body. The sensor data is collected and processed by the Tower Crane Safety Terminal Equipment (TC-STE) installed in the driver's operating room. Wireless communication between each TC-STE and the Local Monitoring Terminal (LMT) at the ground worksite were fulfilled through a Zigbee wireless network. LMT can share the status information of the whole group with each TC-STE, while the LMT records the real-time data and reports it to the Remote Supervision Platform (RSP) through General Packet Radio Service (GPRS). Based on the global status data of the whole group, an anti-collision algorithm was executed in each TC-STE to ensure the safety of each tower crane during construction. Remote supervision can be fulfilled using our client software installed on a personal computer (PC) or smartphone. SMS-TC could be considered as a promising practical application that combines a Wireless Sensor Network with the Internet of Things.

Economic-Analysis Program for a Communication System

NASA Technical Reports Server (NTRS)

Chamberlain, R. G.

1986-01-01

Prices and profits of alternative designs compared. Objective of Land Mobile Satellite Service Finance Report (LMSS) program is to provide means for comparing alternative designs of LMSS systems. Program is Multiplan worksheet program. Labels used in worksheet chosen for satellite-based cellular communication service, but analysis not restricted to such cases. LMSS written for interactive execution with Multiplan (version 1.2) and implemented on IBM PC series computer operating under DOS (version 2.11).

Tablet PC Enabled Body Sensor System for Rural Telehealth Applications

PubMed Central

Panicker, Nitha V.; Kumar, A. Sukesh

2016-01-01

Telehealth systems benefit from the rapid growth of mobile communication technology for measuring physiological signals. Development and validation of a tablet PC enabled noninvasive body sensor system for rural telehealth application are discussed in this paper. This system includes real time continuous collection of physiological parameters (blood pressure, pulse rate, and temperature) and fall detection of a patient with the help of a body sensor unit and wireless transmission of the acquired information to a tablet PC handled by the medical staff in a Primary Health Center (PHC). Abnormal conditions are automatically identified and alert messages are given to the medical officer in real time. Clinical validation is performed in a real environment and found to be successful. Bland-Altman analysis is carried out to validate the wrist blood pressure sensor used. The system works well for all measurements. PMID:26884757

Advanced Communication and Networking Technologies for Mars Exploration

NASA Technical Reports Server (NTRS)

Bhasin, Kul; Hayden, Jeff; Agre, Jonathan R.; Clare, Loren P.; Yan, Tsun-Yee

2001-01-01

Next-generation Mars communications networks will provide communications and navigation services to a wide variety of Mars science vehicles including: spacecraft that are arriving at Mars, spacecraft that are entering and descending in the Mars atmosphere, scientific orbiter spacecraft, spacecraft that return Mars samples to Earth, landers, rovers, aerobots, airplanes, and sensing pods. In the current architecture plans, the communication services will be provided using capabilities deployed on the science vehicles as well as dedicated communication satellites that will together make up the Mars network. This network will evolve as additional vehicles arrive, depart or end their useful missions. Cost savings and increased reliability will result from the ability to share communication services between missions. This paper discusses the basic architecture that is needed to support the Mars Communications Network part of NASA's Space Science Enterprise (SSE) communications architecture. The network may use various networking technologies such as those employed in the terrestrial Internet, as well as special purpose deep-space protocols to move data and commands autonomously between vehicles, at disparate Mars vicinity sites (on the surface or in near-Mars space) and between Mars vehicles and earthbound users. The architecture of the spacecraft on-board local communications is being reconsidered in light of these new networking requirements. The trend towards increasingly autonomous operation of the spacecraft is aimed at reducing the dependence on resource scheduling provided by Earth-based operators and increasing system fault tolerance. However, these benefits will result in increased communication and software development requirements. As a result, the envisioned Mars communications infrastructure requires both hardware and protocol technology advancements. This paper will describe a number of the critical technology needs and some of the ongoing research activities.

Capacity on wireless quantum cellular communication system

NASA Astrophysics Data System (ADS)

Zhou, Xiang-Zhen; Yu, Xu-Tao; Zhang, Zai-Chen

2018-03-01

Quantum technology is making excellent prospects in future communication networks. Entanglement generation and purification are two major components in quantum networks. Combining these two techniques with classical cellular mobile communication, we proposed a novel wireless quantum cellular(WQC) communication system which is possible to realize commercial mobile quantum communication. In this paper, the architecture and network topology of WQC communication system are discussed, the mathematical model of WQC system is extracted and the serving capacity, indicating the ability to serve customers, is defined and calculated under certain circumstances.

The Internet: How Fast Can You Download?

ERIC Educational Resources Information Center

Shearer, Ron

1997-01-01

Discusses faster modems for downloading information from the Internet that may become available through cable or telephone industries. Topics include ADSL (Asymmetric Digital Subscriber Line) modems; Direct PC--downloading satellite transmissions; Land Multichannel Distribution System (LMDS)--a wireless communication device; and Internet…

Heterogeneous Spacecraft Networks

NASA Technical Reports Server (NTRS)

Nakamura, Yosuke (Inventor); Faber, Nicolas T. (Inventor); Frost, Chad R. (Inventor); Alena, Richard L. (Inventor)

2018-01-01

The present invention provides a heterogeneous spacecraft network including a network management architecture to facilitate communication between a plurality of operations centers and a plurality of data user communities. The network management architecture includes a plurality of network nodes in communication with the plurality of operations centers. The present invention also provides a method of communication for a heterogeneous spacecraft network. The method includes: transmitting data from a first space segment to a first ground segment; transmitting the data from the first ground segment to a network management architecture; transmitting data from a second space segment to a second ground segment, the second space and ground segments having incompatible communication systems with the first space and ground segments; transmitting the data from the second ground station to the network management architecture; and, transmitting data from the network management architecture to a plurality of data user communities.

Delay and Disruption Tolerant Networking MACHETE Model

NASA Technical Reports Server (NTRS)

Segui, John S.; Jennings, Esther H.; Gao, Jay L.

2011-01-01

To verify satisfaction of communication requirements imposed by unique missions, as early as 2000, the Communications Networking Group at the Jet Propulsion Laboratory (JPL) saw the need for an environment to support interplanetary communication protocol design, validation, and characterization. JPL's Multi-mission Advanced Communications Hybrid Environment for Test and Evaluation (MACHETE), described in Simulator of Space Communication Networks (NPO-41373) NASA Tech Briefs, Vol. 29, No. 8 (August 2005), p. 44, combines various commercial, non-commercial, and in-house custom tools for simulation and performance analysis of space networks. The MACHETE environment supports orbital analysis, link budget analysis, communications network simulations, and hardware-in-the-loop testing. As NASA is expanding its Space Communications and Navigation (SCaN) capabilities to support planned and future missions, building infrastructure to maintain services and developing enabling technologies, an important and broader role is seen for MACHETE in design-phase evaluation of future SCaN architectures. To support evaluation of the developing Delay Tolerant Networking (DTN) field and its applicability for space networks, JPL developed MACHETE models for DTN Bundle Protocol (BP) and Licklider/Long-haul Transmission Protocol (LTP). DTN is an Internet Research Task Force (IRTF) architecture providing communication in and/or through highly stressed networking environments such as space exploration and battlefield networks. Stressed networking environments include those with intermittent (predictable and unknown) connectivity, large and/or variable delays, and high bit error rates. To provide its services over existing domain specific protocols, the DTN protocols reside at the application layer of the TCP/IP stack, forming a store-and-forward overlay network. The key capabilities of the Bundle Protocol include custody-based reliability, the ability to cope with intermittent connectivity, the ability to take advantage of scheduled and opportunistic connectivity, and late binding of names to addresses.

Germline mutation prevalence in individuals with pancreatic cancer and a history of previous malignancy.

PubMed

Dudley, Beth; Karloski, Eve; Monzon, Federico A; Singhi, Aatur D; Lincoln, Stephen E; Bahary, Nathan; Brand, Randall E

2018-04-15

Approximately 10% of pancreatic adenocarcinoma (PC) cases are attributed to hereditary causes. Individuals with PC and a personal history of another cancer associated with hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) may be more likely to carry germline mutations. Participants with PC and a history of cancer were selected from a pancreatic disease registry. Of 1296 individuals with PC, 149 had a relevant history of cancer. If banked DNA was available, a multigene panel was performed for individuals who had not 1) previously had a mutation identified through clinical testing or 2) undergone clinical multigene panel testing with no mutations detected. Twenty-two of 124 individuals with PC and another HBOC- or LS-related cancer who underwent genetic testing had a mutation identified in a PC susceptibility gene (18%). If prostate cancer is excluded, the mutation prevalence increased to 23% (21/93). Mutation carriers were more likely to have more than 1 previous cancer diagnosis (P = .001), to have had clinical genetic testing (P = .001), and to meet National Comprehensive Cancer Network (NCCN) genetic testing criteria (P < .001). Approximately 23% of mutation carriers did not meet NCCN HBOC or LS testing guidelines based on their personal cancer history and reported cancer history in first-degree relatives. At least 18% of individuals with PC and a personal history of other HBOC- or LS-related cancers carry mutations in a PC susceptibility gene based on our data, suggesting that criteria for genetic testing in individuals with PC should include consideration of previous cancer history. Cancer 2018;124:1691-700. © 2018 American Cancer Society. © 2018 American Cancer Society.

Survey of Ionospheric Pc3-5 ULF Wave Signatures in SuperDARN High Time Resolution Data

NASA Astrophysics Data System (ADS)

Shi, X.; Ruohoniemi, J. M.; Baker, J. B. H.; Lin, D.; Bland, E. C.; Hartinger, M. D.; Scales, W. A.

2018-05-01

Ionospheric signatures of ultralow frequency (ULF) wave in the Pc3-5 band (1.7-40.0 mHz) were surveyed using ˜6-s resolution data from Super Dual Auroral Radar Network (SuperDARN) radars in the Northern Hemisphere from 2010 to 2016. Numerical experiments were conducted to derive wave period-dependent thresholds for automated detection of ULF waves using the Lomb-Scargle periodogram technique. The spatial occurrence distribution, frequency characteristics, seasonal effects, solar wind condition, and geomagnetic activity level dependence have been studied. Pc5 wave events were found to dominate at high and polar latitudes with a most probable frequency of 2.08 ± 0.07 mHz, while Pc3-4 waves were relatively more common at midlatitudes on the nightside with a most probable frequency of 11.39 ± 0.14 mHz. At high latitudes, the occurrence rate of Pc4-5 waves maximizes in the dusk sector and during winter. These events tend to occur during low geomagnetic activity and northward interplanetary magnetic field. For the category of radially bounded but longitudinally extended Pc4 events in the duskside ionosphere, an internal driving source is suggested. At midlatitudes, the poloidal Pc3-4 occurrence rate maximizes premidnight and during equinox. This tendency becomes more prominent with increasing auroral electrojet (AE) index and during southward interplanetary magnetic field, which suggests that many of these events are Pi2 and Pc3-4 pulsations associated with magnetotail dynamics during active geomagnetic intervals. The overall occurrence rate of Pc3-5 wave events is lowest in summer, which suggests that the ionospheric conductivity plays a role in controlling ULF wave occurrence.

NCOA3-mediated upregulation of mucin expression via transcriptional and post-translational changes during the development of pancreatic cancer

PubMed Central

Kumar, S; Das, S; Rachagani, S; Kaur, S; Joshi, S; Johansson, SL; Ponnusamy, MP; Jain, M; Batra, SK

2015-01-01

Pancreatic cancer (PC) is characterized by aberrant overexpression of mucins that contribute to its pathogenesis. Although the inflammatory cytokines contribute to mucin overexpression, the mucin profile of PC is markedly distinct from that of normal or inflamed pancreas. We postulated that de novo expression of various mucins in PC involves chromatin modifications. Analysis of chromatin modifying enzymes by PCR array identified differential expression of NCOA3 in MUC4-expressing PC cell lines. Immunohistochemistry analysis in tumor tissues from patients and spontaneous mouse models, and microarray analysis following the knockdown of NCOA3 were performed to elucidate its role in mucin regulation and overall impact on PC. Silencing of NCOA3 in PC cell lines resulted in significant downregulation of two most differentially expressed mucins in PC, MUC4 and MUC1 (P<0.01). Immunohistochemistry analysis in PC tissues and metastatic lesions established an association between NCOA3 and mucin (MUC1 and MUC4) expression. Spontaneous mouse model of PC (K-rasG12D; Pdx-1cre) showed early expression of Ncoa3 during preneoplastic lesions. Mechanistically, NCOA3 knockdown abrogated retinoic acid-mediated MUC4 upregulation by restricting MUC4 promoter accessibility as demonstrated by micrococcus nuclease digestion (P<0.05) and chromatin immuno-precipitation analysis. NCOA3 also created pro-inflammatory conditions by upregulating chemokines like CXCL1, 2, 5 and CCL20 (P<0.001). AKT, ubiquitin C, ERK1/2 and NF-κB occupied dominant nodes in the networks significantly modulated after NCOA3 silencing. In addition, NCOA3 stabilized mucins post translationally through fucosylation by FUT8, as the knockdown of FUT8 resulted in the downregulation of MUC4 and MUC1 at protein levels. PMID:25531332

Algorithms for Data Sharing, Coordination, and Communication in Dynamic Network Settings

DTIC Science & Technology

2007-12-03

problems in dynamic networks, focusing on mobile networks with wireless communication. Problems studied include data management, time synchronization ...The discovery of a fundamental limitation in capabilities for time synchronization in large networks. (2) The identification and development of the...Problems studied include data management, time synchronization , communication problems (broadcast, geocast, and point-to-point routing), distributed

Computation and Communication Evaluation of an Authentication Mechanism for Time-Triggered Networked Control Systems

PubMed Central

Martins, Goncalo; Moondra, Arul; Dubey, Abhishek; Bhattacharjee, Anirban; Koutsoukos, Xenofon D.

2016-01-01

In modern networked control applications, confidentiality and integrity are important features to address in order to prevent against attacks. Moreover, network control systems are a fundamental part of the communication components of current cyber-physical systems (e.g., automotive communications). Many networked control systems employ Time-Triggered (TT) architectures that provide mechanisms enabling the exchange of precise and synchronous messages. TT systems have computation and communication constraints, and with the aim to enable secure communications in the network, it is important to evaluate the computational and communication overhead of implementing secure communication mechanisms. This paper presents a comprehensive analysis and evaluation of the effects of adding a Hash-based Message Authentication (HMAC) to TT networked control systems. The contributions of the paper include (1) the analysis and experimental validation of the communication overhead, as well as a scalability analysis that utilizes the experimental result for both wired and wireless platforms and (2) an experimental evaluation of the computational overhead of HMAC based on a kernel-level Linux implementation. An automotive application is used as an example, and the results show that it is feasible to implement a secure communication mechanism without interfering with the existing automotive controller execution times. The methods and results of the paper can be used for evaluating the performance impact of security mechanisms and, thus, for the design of secure wired and wireless TT networked control systems. PMID:27463718

Computation and Communication Evaluation of an Authentication Mechanism for Time-Triggered Networked Control Systems.

PubMed

Martins, Goncalo; Moondra, Arul; Dubey, Abhishek; Bhattacharjee, Anirban; Koutsoukos, Xenofon D

2016-07-25

In modern networked control applications, confidentiality and integrity are important features to address in order to prevent against attacks. Moreover, network control systems are a fundamental part of the communication components of current cyber-physical systems (e.g., automotive communications). Many networked control systems employ Time-Triggered (TT) architectures that provide mechanisms enabling the exchange of precise and synchronous messages. TT systems have computation and communication constraints, and with the aim to enable secure communications in the network, it is important to evaluate the computational and communication overhead of implementing secure communication mechanisms. This paper presents a comprehensive analysis and evaluation of the effects of adding a Hash-based Message Authentication (HMAC) to TT networked control systems. The contributions of the paper include (1) the analysis and experimental validation of the communication overhead, as well as a scalability analysis that utilizes the experimental result for both wired and wireless platforms and (2) an experimental evaluation of the computational overhead of HMAC based on a kernel-level Linux implementation. An automotive application is used as an example, and the results show that it is feasible to implement a secure communication mechanism without interfering with the existing automotive controller execution times. The methods and results of the paper can be used for evaluating the performance impact of security mechanisms and, thus, for the design of secure wired and wireless TT networked control systems.

The network and transmission of based on the principle of laser multipoint communication

NASA Astrophysics Data System (ADS)

Fu, Qiang; Liu, Xianzhu; Jiang, Huilin; Hu, Yuan; Jiang, Lun

2014-11-01

Space laser communication is the perfectly choose to the earth integrated information backbone network in the future. This paper introduces the structure of the earth integrated information network that is a large capacity integrated high-speed broadband information network, a variety of communications platforms were densely interconnected together, such as the land, sea, air and deep air users or aircraft, the technologies of the intelligent high-speed processing, switching and routing were adopt. According to the principle of maximum effective comprehensive utilization of information resources, get accurately information, fast processing and efficient transmission through inter-satellite, satellite earth, sky and ground station and other links. Namely it will be a space-based, air-based and ground-based integrated information network. It will be started from the trends of laser communication. The current situation of laser multi-point communications were expounded, the transmission scheme of the dynamic multi-point between wireless laser communication n network has been carefully studied, a variety of laser communication network transmission schemes the corresponding characteristics and scope described in detail , described the optical multiplexer machine that based on the multiport form of communication is applied to relay backbone link; the optical multiplexer-based on the form of the segmentation receiver field of view is applied to small angle link, the optical multiplexer-based form of three concentric spheres structure is applied to short distances, motorized occasions, and the multi-point stitching structure based on the rotation paraboloid is applied to inter-satellite communications in detail. The multi-point laser communication terminal apparatus consist of the transmitting and receiving antenna, a relay optical system, the spectroscopic system, communication system and communication receiver transmitter system. The communication forms of optical multiplexer more than four goals or more, the ratio of received power and volume weight will be Obvious advantages, and can track multiple moving targets in flexible.It would to provide reference for the construction of earth integrated information networks.

Molecular communication and networking: opportunities and challenges.

PubMed

Nakano, Tadashi; Moore, Michael J; Wei, Fang; Vasilakos, Athanasios V; Shuai, Jianwei

2012-06-01

The ability of engineered biological nanomachines to communicate with biological systems at the molecular level is anticipated to enable future applications such as monitoring the condition of a human body, regenerating biological tissues and organs, and interfacing artificial devices with neural systems. From the viewpoint of communication theory and engineering, molecular communication is proposed as a new paradigm for engineered biological nanomachines to communicate with the natural biological nanomachines which form a biological system. Distinct from the current telecommunication paradigm, molecular communication uses molecules as the carriers of information; sender biological nanomachines encode information on molecules and release the molecules in the environment, the molecules then propagate in the environment to receiver biological nanomachines, and the receiver biological nanomachines biochemically react with the molecules to decode information. Current molecular communication research is limited to small-scale networks of several biological nanomachines. Key challenges to bridge the gap between current research and practical applications include developing robust and scalable techniques to create a functional network from a large number of biological nanomachines. Developing networking mechanisms and communication protocols is anticipated to introduce new avenues into integrating engineered and natural biological nanomachines into a single networked system. In this paper, we present the state-of-the-art in the area of molecular communication by discussing its architecture, features, applications, design, engineering, and physical modeling. We then discuss challenges and opportunities in developing networking mechanisms and communication protocols to create a network from a large number of bio-nanomachines for future applications.

A spiking neural network model of self-organized pattern recognition in the early mammalian olfactory system.

PubMed

Kaplan, Bernhard A; Lansner, Anders

2014-01-01

Olfactory sensory information passes through several processing stages before an odor percept emerges. The question how the olfactory system learns to create odor representations linking those different levels and how it learns to connect and discriminate between them is largely unresolved. We present a large-scale network model with single and multi-compartmental Hodgkin-Huxley type model neurons representing olfactory receptor neurons (ORNs) in the epithelium, periglomerular cells, mitral/tufted cells and granule cells in the olfactory bulb (OB), and three types of cortical cells in the piriform cortex (PC). Odor patterns are calculated based on affinities between ORNs and odor stimuli derived from physico-chemical descriptors of behaviorally relevant real-world odorants. The properties of ORNs were tuned to show saturated response curves with increasing concentration as seen in experiments. On the level of the OB we explored the possibility of using a fuzzy concentration interval code, which was implemented through dendro-dendritic inhibition leading to winner-take-all like dynamics between mitral/tufted cells belonging to the same glomerulus. The connectivity from mitral/tufted cells to PC neurons was self-organized from a mutual information measure and by using a competitive Hebbian-Bayesian learning algorithm based on the response patterns of mitral/tufted cells to different odors yielding a distributed feed-forward projection to the PC. The PC was implemented as a modular attractor network with a recurrent connectivity that was likewise organized through Hebbian-Bayesian learning. We demonstrate the functionality of the model in a one-sniff-learning and recognition task on a set of 50 odorants. Furthermore, we study its robustness against noise on the receptor level and its ability to perform concentration invariant odor recognition. Moreover, we investigate the pattern completion capabilities of the system and rivalry dynamics for odor mixtures.

A spiking neural network model of self-organized pattern recognition in the early mammalian olfactory system

PubMed Central

Kaplan, Bernhard A.; Lansner, Anders

2014-01-01

Olfactory sensory information passes through several processing stages before an odor percept emerges. The question how the olfactory system learns to create odor representations linking those different levels and how it learns to connect and discriminate between them is largely unresolved. We present a large-scale network model with single and multi-compartmental Hodgkin–Huxley type model neurons representing olfactory receptor neurons (ORNs) in the epithelium, periglomerular cells, mitral/tufted cells and granule cells in the olfactory bulb (OB), and three types of cortical cells in the piriform cortex (PC). Odor patterns are calculated based on affinities between ORNs and odor stimuli derived from physico-chemical descriptors of behaviorally relevant real-world odorants. The properties of ORNs were tuned to show saturated response curves with increasing concentration as seen in experiments. On the level of the OB we explored the possibility of using a fuzzy concentration interval code, which was implemented through dendro-dendritic inhibition leading to winner-take-all like dynamics between mitral/tufted cells belonging to the same glomerulus. The connectivity from mitral/tufted cells to PC neurons was self-organized from a mutual information measure and by using a competitive Hebbian–Bayesian learning algorithm based on the response patterns of mitral/tufted cells to different odors yielding a distributed feed-forward projection to the PC. The PC was implemented as a modular attractor network with a recurrent connectivity that was likewise organized through Hebbian–Bayesian learning. We demonstrate the functionality of the model in a one-sniff-learning and recognition task on a set of 50 odorants. Furthermore, we study its robustness against noise on the receptor level and its ability to perform concentration invariant odor recognition. Moreover, we investigate the pattern completion capabilities of the system and rivalry dynamics for odor mixtures. PMID:24570657

Palliative care knowledge and attitudes among oncology nurses in Qatar.

PubMed

Al-Kindi, Sadeer G; Zeinah, Ghaith F Abu; Hassan, Azza Adel

2014-08-01

Formal palliative care (PC) education is lacking in the middle eastern state of Qatar. This study was done to assess the need for PC education among oncology nurses in Qatar. In March 2012, a self-constructed questionnaire was distributed to 115 nurses at the Qatar National Center for Cancer Care and Research. A total of 115 nurses responded to the questionnaire. The majority (87.8%) were female. Although 60% had more than 10 years of work experience, only 31% had received formal training in PC, with only 6.1% having completed postgraduate training. The majority (63%) of responders attributed this issue to unavailability of PC courses rather than lack of time, interest, or financial issues. Currently, only 16.7% did not express interest in the field, with 56% showing some kind of interest. In terms of knowledge, 54% of the responders were familiar with the World Health Organization ladder for pain relief. Only 43.6% know about Palliative Performance Scale, and half of the nurses know the Edmonton Symptom Assessment System. Overall, 56% of the nurses indicated a need for training in more than 1 aspect. These aspects included training in care of the dying patients (14.6%), communication strategies (22%), caregiver support (10.6%), psychosocial care (15%), pain management (10.2%), other symptom management (13%), and other ethical/spiritual issues (14.2%). There is a clear deficiency in formal PC education among the nurses at the National Center for Cancer Care and Research, in Qatar. This is reflected by their lack of experience and exposure to PC and their mediocre knowledge in the field. This could be attributed to the fact that formal PC service was established only recently in Qatar (2008). Formal training courses in PC nursing are required. © The Author(s) 2013.

A Novel Dual Separate Paths (DSP) Algorithm Providing Fault-Tolerant Communication for Wireless Sensor Networks.

PubMed

Tien, Nguyen Xuan; Kim, Semog; Rhee, Jong Myung; Park, Sang Yoon

2017-07-25

Fault tolerance has long been a major concern for sensor communications in fault-tolerant cyber physical systems (CPSs). Network failure problems often occur in wireless sensor networks (WSNs) due to various factors such as the insufficient power of sensor nodes, the dislocation of sensor nodes, the unstable state of wireless links, and unpredictable environmental interference. Fault tolerance is thus one of the key requirements for data communications in WSN applications. This paper proposes a novel path redundancy-based algorithm, called dual separate paths (DSP), that provides fault-tolerant communication with the improvement of the network traffic performance for WSN applications, such as fault-tolerant CPSs. The proposed DSP algorithm establishes two separate paths between a source and a destination in a network based on the network topology information. These paths are node-disjoint paths and have optimal path distances. Unicast frames are delivered from the source to the destination in the network through the dual paths, providing fault-tolerant communication and reducing redundant unicast traffic for the network. The DSP algorithm can be applied to wired and wireless networks, such as WSNs, to provide seamless fault-tolerant communication for mission-critical and life-critical applications such as fault-tolerant CPSs. The analyzed and simulated results show that the DSP-based approach not only provides fault-tolerant communication, but also improves network traffic performance. For the case study in this paper, when the DSP algorithm was applied to high-availability seamless redundancy (HSR) networks, the proposed DSP-based approach reduced the network traffic by 80% to 88% compared with the standard HSR protocol, thus improving network traffic performance.

Gossip algorithms in quantum networks

NASA Astrophysics Data System (ADS)

Siomau, Michael

2017-01-01

Gossip algorithms is a common term to describe protocols for unreliable information dissemination in natural networks, which are not optimally designed for efficient communication between network entities. We consider application of gossip algorithms to quantum networks and show that any quantum network can be updated to optimal configuration with local operations and classical communication. This allows to speed-up - in the best case exponentially - the quantum information dissemination. Irrespective of the initial configuration of the quantum network, the update requiters at most polynomial number of local operations and classical communication.

Deciphering the roles of Arabidopsis LPCAT and PAH in phosphatidylcholine homeostasis and pathway coordination for chloroplast lipid synthesis.

PubMed

Wang, Liping; Kazachkov, Michael; Shen, Wenyun; Bai, Mei; Wu, Hong; Zou, Jitao

2014-12-01

Phosphatidylcholine (PC) is a key intermediate in the metabolic network of glycerolipid biosynthesis. Lysophosphatidylcholine acyltransferase (LPCAT) and phosphatidic acid phosphatase (PAH) are two key enzymes of PC homeostasis. We report that LPCAT activity is markedly induced in the Arabidopsis pah mutant. The quadruple pah lpcat mutant, with dual defects in PAH and LPCAT, had a level of lysophosphatidylcholine (LPC) that was much higher than that in the lpcat mutants and a PC content that was higher than that in the pah mutant. Comparative molecular profile analysis of monogalactosyldiacylglycerol and digalactosyldiacylglycerol revealed that both the pah and pah lpcat mutants had increased proportions of 34:6 from the prokaryotic pathway despite differing levels of LPCAT activity. We show that a decreased representation of the C16:0 C18:2 diacylglycerol moiety in PC was a shared feature of pah and pah lpcat, and that this change in PC metabolic profile correlated with the increased prokaryotic contribution to chloroplast lipid synthesis. We detected increased PC deacylation in the pah lpcat mutant that was attributable at least in part to the induced phospholipases. Increased LPC generation was also evident in the pah mutant, but the phospholipases were not induced, raising the possibility that PC deacylation is mediated by the reverse reaction of LPCAT. We discuss possible roles of LPCAT and PAH in PC turnover that impacts lipid pathway coordination for chloroplast lipid synthesis. © 2014 National Research Council Canada. The Plant Journal © 2014 Society For Experimental Biology and John Wiley & Sons.

Investigation of Techniques for Simulating Communications and Tracking Subsystems on Space Station Freedom

NASA Technical Reports Server (NTRS)

Deacetis, Louis A.

1991-01-01

The need to reduce the costs of Space Station Freedom has resulted in a major redesign and downsizing of the Station in general, and its Communications and Tracking (C&T) components in particular. Earlier models and simulations of the C&T Space-to-Ground Subsystem (SGS) in particular are no longer valid. There thus exists a general need for updated, high fidelity simulations of C&T subsystems. This project explored simulation techniques and methods that might be used in developing new simulations of C&T subsystems, including the SGS. Three requirements were placed on the simulations to be developed: (1) they run on IBM PC/XT/AT compatible computers; (2) they be written in Ada as much as possible; and (3) since control and monitoring of the C&T subsystems will involve communication via a MIL-STD-1553B serial bus, that the possibility of commanding the simulator and monitoring its sensors via that bus be included in the design of the simulator. The result of the project is a prototype of a simulation of the Assembly/Contingency Transponder of the SGS, written in Ada, which can be controlled from another PC via a MIL-STD-1553B bus.

Complex networks in the Euclidean space of communicability distances

NASA Astrophysics Data System (ADS)

Estrada, Ernesto

2012-06-01

We study the properties of complex networks embedded in a Euclidean space of communicability distances. The communicability distance between two nodes is defined as the difference between the weighted sum of walks self-returning to the nodes and the weighted sum of walks going from one node to the other. We give some indications that the communicability distance identifies the least crowded routes in networks where simultaneous submission of packages is taking place. We define an index Q based on communicability and shortest path distances, which allows reinterpreting the “small-world” phenomenon as the region of minimum Q in the Watts-Strogatz model. It also allows the classification and analysis of networks with different efficiency of spatial uses. Consequently, the communicability distance displays unique features for the analysis of complex networks in different scenarios.

Mapping Ad Hoc Communications Network of a Large Number Fixed-Wing UAV Swarm

DTIC Science & Technology

2017-03-01

partitioned sub-swarms. The work covered in this thesis is to build a model of the NPS swarm’s communication network in ns-3 simulation software and use...partitioned sub- swarms. The work covered in this thesis is to build a model of the NPS swarm’s communication network in ns-3 simulation software and...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS MAPPING AD HOC COMMUNICATIONS NETWORK OF A LARGE NUMBER FIXED-WING UAV SWARM by Alexis

Embeddable Reconfigurable Neuroprocessors

NASA Technical Reports Server (NTRS)

Daud, Taher; Duong, Tuan; Langenbacher, Harry; Tran, Mua; Thakoor, Anil

1993-01-01

Reconfigurable and cascadable building block neural network chips, fabricated using analog VLSI design tools, are interfaced to a PC. The building block chip designs, the cascadability and the hardware-in-the-loop supervised learning aspects of these chips are described.

Real-time detection of neurite outgrowth using microfluidic device

NASA Astrophysics Data System (ADS)

Kim, Samhwan; Jang, Jongmoon; Choi, Hongsoo; Moon, Cheil

2013-05-01

We developed a simple method for real-time detection of the neurite outgrowth using microfluidic device. Our microfluidic device contains three compartmentalized channels which are for cell seeding, hydrogel and growth factors. Collagen gel is filled in the middle channel and pheochromocytoma (PC12) cells are seeded in the left channel. To induce differentiation of PC12 cells, 50 ng/ml to1000 ng/ml of nerve growth factor (NGF) is introduced into the right channel. After three days of NGF treatment, PC12 cells begin to extend neurites and formed neurite network from sixth day. Quantification of neurite outgrowth is analyzed by measuring the total area of neurites. On sixth day, the area is doubled compared to the area on third day and increases by 20 times on ninth day.

a Linux PC Cluster for Lattice QCD with Exact Chiral Symmetry

NASA Astrophysics Data System (ADS)

Chiu, Ting-Wai; Hsieh, Tung-Han; Huang, Chao-Hsi; Huang, Tsung-Ren

A computational system for lattice QCD with overlap Dirac quarks is described. The platform is a home-made Linux PC cluster, built with off-the-shelf components. At present the system constitutes of 64 nodes, with each node consisting of one Pentium 4 processor (1.6/2.0/2.5 GHz), one Gbyte of PC800/1066 RDRAM, one 40/80/120 Gbyte hard disk, and a network card. The computationally intensive parts of our program are written in SSE2 codes. The speed of our system is estimated to be 70 Gflops, and its price/performance ratio is better than $1.0/Mflops for 64-bit (double precision) computations in quenched QCD. We discuss how to optimize its hardware and software for computing propagators of overlap Dirac quarks.

Leveraging the NPS Femto Satellite for Alternative Satellite Communication Networks

DTIC Science & Technology

2017-09-01

the next-generation NPSFS. 14. SUBJECT TERMS space , Femto satellite, NPSFS, network, communication , Arduino, RockBlock, Iridium Modem 15. NUMBER...provides a proof of concept for using Naval Postgraduate School Femto Satellites (NPSFS) as an alternative communication space -based network. The...We need several physical and procedural elements to conduct communication through space and using the electromagnetic spectrum. 1. Power Any

High-Capacity Ground Communications to Support Future Space Missions: A Forecast of Ground Communications Challenges in the 2010-2020 Period

NASA Technical Reports Server (NTRS)

Markley, Richard W.

2003-01-01

The purpose of this presentation is to identify major challenges involved in space ground communications networks to support space flight missions over the next 20 years. The presentation focus is on the Deep Space Network and its customers, but the forecast is applicable to all space ground communications networks.

An algorithm for direct causal learning of influences on patient outcomes.

PubMed

Rathnam, Chandramouli; Lee, Sanghoon; Jiang, Xia

2017-01-01

This study aims at developing and introducing a new algorithm, called direct causal learner (DCL), for learning the direct causal influences of a single target. We applied it to both simulated and real clinical and genome wide association study (GWAS) datasets and compared its performance to classic causal learning algorithms. The DCL algorithm learns the causes of a single target from passive data using Bayesian-scoring, instead of using independence checks, and a novel deletion algorithm. We generate 14,400 simulated datasets and measure the number of datasets for which DCL correctly and partially predicts the direct causes. We then compare its performance with the constraint-based path consistency (PC) and conservative PC (CPC) algorithms, the Bayesian-score based fast greedy search (FGS) algorithm, and the partial ancestral graphs algorithm fast causal inference (FCI). In addition, we extend our comparison of all five algorithms to both a real GWAS dataset and real breast cancer datasets over various time-points in order to observe how effective they are at predicting the causal influences of Alzheimer's disease and breast cancer survival. DCL consistently outperforms FGS, PC, CPC, and FCI in discovering the parents of the target for the datasets simulated using a simple network. Overall, DCL predicts significantly more datasets correctly (McNemar's test significance: p<0.0001) than any of the other algorithms for these network types. For example, when assessing overall performance (simple and complex network results combined), DCL correctly predicts approximately 1400 more datasets than the top FGS method, 1600 more datasets than the top CPC method, 4500 more datasets than the top PC method, and 5600 more datasets than the top FCI method. Although FGS did correctly predict more datasets than DCL for the complex networks, and DCL correctly predicted only a few more datasets than CPC for these networks, there is no significant difference in performance between these three algorithms for this network type. However, when we use a more continuous measure of accuracy, we find that all the DCL methods are able to better partially predict more direct causes than FGS and CPC for the complex networks. In addition, DCL consistently had faster runtimes than the other algorithms. In the application to the real datasets, DCL identified rs6784615, located on the NISCH gene, and rs10824310, located on the PRKG1 gene, as direct causes of late onset Alzheimer's disease (LOAD) development. In addition, DCL identified ER category as a direct predictor of breast cancer mortality within 5 years, and HER2 status as a direct predictor of 10-year breast cancer mortality. These predictors have been identified in previous studies to have a direct causal relationship with their respective phenotypes, supporting the predictive power of DCL. When the other algorithms discovered predictors from the real datasets, these predictors were either also found by DCL or could not be supported by previous studies. Our results show that DCL outperforms FGS, PC, CPC, and FCI in almost every case, demonstrating its potential to advance causal learning. Furthermore, our DCL algorithm effectively identifies direct causes in the LOAD and Metabric GWAS datasets, which indicates its potential for clinical applications. Copyright © 2016 Elsevier B.V. All rights reserved.

Ablation as targeted perturbation to rewire communication network of persistent atrial fibrillation

PubMed Central

Tao, Susumu; Way, Samuel F.; Garland, Joshua; Chrispin, Jonathan; Ciuffo, Luisa A.; Balouch, Muhammad A.; Nazarian, Saman; Spragg, David D.; Marine, Joseph E.; Berger, Ronald D.; Calkins, Hugh

2017-01-01

Persistent atrial fibrillation (AF) can be viewed as disintegrated patterns of information transmission by action potential across the communication network consisting of nodes linked by functional connectivity. To test the hypothesis that ablation of persistent AF is associated with improvement in both local and global connectivity within the communication networks, we analyzed multi-electrode basket catheter electrograms of 22 consecutive patients (63.5 ± 9.7 years, 78% male) during persistent AF before and after the focal impulse and rotor modulation-guided ablation. Eight patients (36%) developed recurrence within 6 months after ablation. We defined communication networks of AF by nodes (cardiac tissue adjacent to each electrode) and edges (mutual information between pairs of nodes). To evaluate patient-specific parameters of communication, thresholds of mutual information were applied to preserve 10% to 30% of the strongest edges. There was no significant difference in network parameters between both atria at baseline. Ablation effectively rewired the communication network of persistent AF to improve the overall connectivity. In addition, successful ablation improved local connectivity by increasing the average clustering coefficient, and also improved global connectivity by decreasing the characteristic path length. As a result, successful ablation improved the efficiency and robustness of the communication network by increasing the small-world index. These changes were not observed in patients with AF recurrence. Furthermore, a significant increase in the small-world index after ablation was associated with synchronization of the rhythm by acute AF termination. In conclusion, successful ablation rewires communication networks during persistent AF, making it more robust, efficient, and easier to synchronize. Quantitative analysis of communication networks provides not only a mechanistic insight that AF may be sustained by spatially localized sources and global connectivity, but also patient-specific metrics that could serve as a valid endpoint for therapeutic interventions. PMID:28678805

BioNet Digital Communications Framework

NASA Technical Reports Server (NTRS)

Gifford, Kevin; Kuzminsky, Sebastian; Williams, Shea

2010-01-01

BioNet v2 is a peer-to-peer middleware that enables digital communication devices to talk to each other. It provides a software development framework, standardized application, network-transparent device integration services, a flexible messaging model, and network communications for distributed applications. BioNet is an implementation of the Constellation Program Command, Control, Communications and Information (C3I) Interoperability specification, given in CxP 70022-01. The system architecture provides the necessary infrastructure for the integration of heterogeneous wired and wireless sensing and control devices into a unified data system with a standardized application interface, providing plug-and-play operation for hardware and software systems. BioNet v2 features a naming schema for mobility and coarse-grained localization information, data normalization within a network-transparent device driver framework, enabling of network communications to non-IP devices, and fine-grained application control of data subscription band width usage. BioNet directly integrates Disruption Tolerant Networking (DTN) as a communications technology, enabling networked communications with assets that are only intermittently connected including orbiting relay satellites and planetary rover vehicles.

Spacecraft Will Communicate "on the Fly"

NASA Technical Reports Server (NTRS)

Laufenberg, Lawrence

2003-01-01

As NASA probes deeper into space, the distance between sensor and scientist increases, as does the time delay. NASA needs to close that gap, while integrating more spacecraft types and missions-from near-Earth orbit to deep space. To speed and integrate communications from space missions to scientists on Earth and back again. NASA needs a comprehensive, high-performance communications network. To this end, the CICT Programs Space Communications (SC) Project is providing technologies for building the Space Internet which will consist of large backbone network, mid-size access networks linked to the backbones, and smaller, ad-hoc network linked to the access network. A key component will be mobile, wireless networks for spacecraft flying in different configurations.

In-House Communication Support System Based on the Information Propagation Model Utilizes Social Network

NASA Astrophysics Data System (ADS)

Takeuchi, Susumu; Teranishi, Yuuichi; Harumoto, Kaname; Shimojo, Shinji

Almost all companies are now utilizing computer networks to support speedier and more effective in-house information-sharing and communication. However, existing systems are designed to support communications only within the same department. Therefore, in our research, we propose an in-house communication support system which is based on the “Information Propagation Model (IPM).” The IPM is proposed to realize word-of-mouth communication in a social network, and to support information-sharing on the network. By applying the system in a real company, we found that information could be exchanged between different and unrelated departments, and such exchanges of information could help to build new relationships between the users who are apart on the social network.

On Applications of Disruption Tolerant Networking to Optical Networking in Space

NASA Technical Reports Server (NTRS)

Hylton, Alan Guy; Raible, Daniel E.; Juergens, Jeffrey; Iannicca, Dennis

2012-01-01

The integration of optical communication links into space networks via Disruption Tolerant Networking (DTN) is a largely unexplored area of research. Building on successful foundational work accomplished at JPL, we discuss a multi-hop multi-path network featuring optical links. The experimental test bed is constructed at the NASA Glenn Research Center featuring multiple Ethernet-to-fiber converters coupled with free space optical (FSO) communication channels. The test bed architecture models communication paths from deployed Mars assets to the deep space network (DSN) and finally to the mission operations center (MOC). Reliable versus unreliable communication methods are investigated and discussed; including reliable transport protocols, custody transfer, and fragmentation. Potential commercial applications may include an optical communications infrastructure deployment to support developing nations and remote areas, which are unburdened with supporting an existing heritage means of telecommunications. Narrow laser beam widths and control of polarization states offer inherent physical layer security benefits with optical communications over RF solutions. This paper explores whether or not DTN is appropriate for space-based optical networks, optimal payload sizes, reliability, and a discussion on security.

Advancing Underwater Acoustic Communication for Autonomous Distributed Networks via Sparse Channel Sensing, Coding, and Navigation Support

DTIC Science & Technology

2014-09-30

underwater acoustic communication technologies for autonomous distributed underwater networks , through innovative signal processing, coding, and...4. TITLE AND SUBTITLE Advancing Underwater Acoustic Communication for Autonomous Distributed Networks via Sparse Channel Sensing, Coding, and...coding: 3) OFDM modulated dynamic coded cooperation in underwater acoustic channels; 3 Localization, Networking , and Testbed: 4) On-demand

GLOBECOM '88 - IEEE Global Telecommunications Conference and Exhibition, Hollywood, FL, Nov. 28-Dec. 1, 1988, Conference Record. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

Various papers on communications for the information age are presented. Among the general topics considered are: telematic services and terminals, satellite communications, telecommunications mangaement network, control of integrated broadband networks, advances in digital radio systems, the intelligent network, broadband networks and services deployment, future switch architectures, performance analysis of computer networks, advances in spread spectrum, optical high-speed LANs, and broadband switching and networks. Also addressed are: multiple access protocols, video coding techniques, modulation and coding, photonic switching, SONET terminals and applications, standards for video coding, digital switching, progress in MANs, mobile and portable radio, software design for improved maintainability, multipath propagation and advanced countermeasure, data communication, network control and management, fiber in the loop, network algorithm and protocols, and advances in computer communications.

Prenatal Cocaine Disrupts Serotonin Signaling-Dependent Behaviors: Implications for Sex Differences, Early Stress and Prenatal SSRI Exposure

PubMed Central

Williams, Sarah K; Lauder, Jean M; Johns, Josephine M

2011-01-01

Prenatal cocaine (PC) exposure negatively impacts the developing nervous system, including numerous changes in serotonergic signaling. Cocaine, a competitive antagonist of the serotonin transporter, similar to selective serotonin reuptake inhibitors (SSRIs), also blocks dopamine and norepinephrine transporters, leaving the direct mechanism through which cocaine disrupts the developing serotonin system unclear. In order to understand the role of the serotonin transporter in cocaine’s effect on the serotonergic system, we compare reports concerning PC and prenatal antidepressant exposure and conclude that PC exposure affects many facets of serotonergic signaling (serotonin levels, receptors, transporters) and that these effects differ significantly from what is observed following prenatal SSRI exposure. Alterations in serotonergic signaling are dependent on timing of exposure, test regimens, and sex. Following PC exposure, behavioral disturbances are observed in attention, emotional behavior and stress response, aggression, social behavior, communication, and like changes in serotonergic signaling, these effects depend on sex, age and developmental exposure. Vulnerability to the effects of PC exposure can be mediated by several factors, including allelic variance in serotonergic signaling genes, being male (although fewer studies have investigated female offspring), and experiencing the adverse early environments that are commonly coincident with maternal drug use. Early environmental stress results in disruptions in serotonergic signaling analogous to those observed with PC exposure and these may interact to produce greater behavioral effects observed in children of drug-abusing mothers. We conclude that based on past evidence, future studies should put a greater emphasis on including females and monitoring environmental factors when studying the impact of PC exposure. PMID:22379462

Two schemes for rapid generation of digital video holograms using PC cluster

NASA Astrophysics Data System (ADS)

Park, Hanhoon; Song, Joongseok; Kim, Changseob; Park, Jong-Il

2017-12-01

Computer-generated holography (CGH), which is a process of generating digital holograms, is computationally expensive. Recently, several methods/systems of parallelizing the process using graphic processing units (GPUs) have been proposed. Indeed, use of multiple GPUs or a personal computer (PC) cluster (each PC with GPUs) enabled great improvements in the process speed. However, extant literature has less often explored systems involving rapid generation of multiple digital holograms and specialized systems for rapid generation of a digital video hologram. This study proposes a system that uses a PC cluster and is able to more efficiently generate a video hologram. The proposed system is designed to simultaneously generate multiple frames and accelerate the generation by parallelizing the CGH computations across a number of frames, as opposed to separately generating each individual frame while parallelizing the CGH computations within each frame. The proposed system also enables the subprocesses for generating each frame to execute in parallel through multithreading. With these two schemes, the proposed system significantly reduced the data communication time for generating a digital hologram when compared with that of the state-of-the-art system.

Pancreatic Cancer-Critical Examination of the Global Research Architecture and Recent Scientific Developments.

PubMed

Schöffel, Norman; Krempel, Meike; Bundschuh, Matthias; Bendels, Michael H; Brüggmann, Dörthe; Groneberg, David A

2016-11-01

Despite decades of effort, the 5-year overall survival rate of pancreatic cancer (PC) remains at only approximately 5%. Until now, no detailed knowledge regarding the worldwide research architecture of PC has yet been established. Hence, we conducted this scientometric analysis to quantify the global research activity in this field. The total research productivity was screened and research output of countries, categories, individual institutions, authors, and their collaborative networks were analyzed by the new quality and quantity indices in science platform. Results were visualized via state-of-the-art density equalizing mapping projections. The results indicated that Japan, Germany, and the United States played a leading role regarding output activity, multilateral, and bilateral cooperations. Within the past decades, the topic PC has developed into a scientific field covering many subject areas. Recently published studies predict that the scientific progress will be mainly depending on international cooperations; we can confirm that development by now. We conclude that the field of PC is constantly progressing in which the influence of international cooperations on the scientific progress is of increasing importance. Nevertheless, research in the field of PC still needs to be strengthened to reduce morbidity and mortality in the future.

Functional connectivity mapping of regions associated with self- and other-processing.

PubMed

Murray, Ryan J; Debbané, Martin; Fox, Peter T; Bzdok, Danilo; Eickhoff, Simon B

2015-04-01

Neuroscience literature increasingly suggests a conceptual self composed of interacting neural regions, rather than independent local activations, yet such claims have yet to be investigated. We, thus, combined task-dependent meta-analytic connectivity modeling (MACM) with task-independent resting-state (RS) connectivity analysis to delineate the neural network of the self, across both states. Given psychological evidence implicating the self's interdependence on social information, we also delineated the neural network underlying conceptual other-processing. To elucidate the relation between the self-/other-networks and their function, we mined the MACM metadata to generate a cognitive-behavioral profile for an empirically identified region specific to conceptual self, the pregenual anterior cingulate (pACC), and conceptual other, posterior cingulate/precuneus (PCC/PC). Mining of 7,200 published, task-dependent, neuroimaging studies, using healthy human subjects, yielded 193 studies activating the self-related seed and were conjoined with RS connectivity analysis to delineate a differentiated self-network composed of the pACC (seed) and anterior insula, relative to other functional connectivity. Additionally, 106 studies activating the other-related seed were conjoined with RS connectivity analysis to delineate a differentiated other-network of PCC/PC (seed) and angular gyrus/temporoparietal junction, relative to self-functional connectivity. The self-network seed related to emotional conflict resolution and motivational processing, whereas the other-network seed related to socially oriented processing and contextual information integration. Notably, our findings revealed shared RS connectivity between ensuing self-/other-networks within the ventromedial prefrontal cortex and medial orbitofrontal cortex, suggesting self-updating via integration of self-relevant social information. We, therefore, present initial neurobiological evidence corroborating the increasing claims of an intricate self-network, the architecture of which may promote social value processing. © 2014 Wiley Periodicals, Inc.

Using Social Network Analysis to Investigate Positive EOL Communication.

PubMed

Xu, Jiayun; Yang, Rumei; Wilson, Andrew; Reblin, Maija; Clayton, Margaret F; Ellington, Lee

2018-04-30

End of life (EOL) communication is a complex process involving the whole family and multiple care providers. Applications of analysis techniques that account for communication beyond the patient and patient/provider, will improve clinical understanding of EOL communication. To introduce the use of social network analysis to EOL communication data, and to provide an example of applying social network analysis to home hospice interactions. We provide a description of social network analysis using social network analysis to model communication patterns during home hospice nursing visits. We describe three social network attributes (i.e. magnitude, directionality, and reciprocity) in the expression of positive emotion among hospice nurses, family caregivers, and hospice cancer patients. Differences in communication structure by primary family caregiver gender and across time were also examined. Magnitude (frequency) in the expression of positive emotion occurred most often between nurses and caregivers or nurses and patients. Female caregivers directed more positive emotion to nurses, and nurses directed more positive emotion to other family caregivers when the primary family caregiver was male. Reciprocity (mutuality) in positive emotion declined towards day of death, but increased on day of actual patient death. There was variation in reciprocity by the type of positive emotion expressed. Our example demonstrates that social network analysis can be used to better understand the process of EOL communication. Social network analysis can be expanded to other areas of EOL research, such as EOL decision-making and health care teamwork. Copyright © 2018. Published by Elsevier Inc.

Space Link Extension (SLE) Emulation for High-Throughput Network Communication

NASA Technical Reports Server (NTRS)

Murawski, Robert W.; Tchorowski, Nicole; Golden, Bert

2014-01-01

As the data rate requirements for space communications increases, significant stress is placed not only on the wireless satellite communication links, but also on the ground networks which forward data from end-users to remote ground stations. These wide area network (WAN) connections add delay and jitter to the end-to-end satellite communication link, effects which can have significant impacts on the wireless communication link. It is imperative that any ground communication protocol can react to these effects such that the ground network does not become a bottleneck in the communication path to the satellite. In this paper, we present our SCENIC Emulation Lab testbed which was developed to test the CCSDS SLE protocol implementations proposed for use on future NASA communication networks. Our results show that in the presence of realistic levels of network delay, high-throughput SLE communication links can experience significant data rate throttling. Based on our observations, we present some insight into why this data throttling happens, and trace the probable issue back to non-optimal blocking communication which is sup-ported by the CCSDS SLE API recommended practices. These issues were presented as well to the SLE implementation developers which, based on our reports, developed a new release for SLE which we show fixes the SLE blocking issue and greatly improves the protocol throughput. In this paper, we also discuss future developments for our end-to-end emulation lab and how these improvements can be used to develop and test future space communication technologies.

Applying artificial neural networks to predict communication risks in the emergency department.

PubMed

Bagnasco, Annamaria; Siri, Anna; Aleo, Giuseppe; Rocco, Gennaro; Sasso, Loredana

2015-10-01

To describe the utility of artificial neural networks in predicting communication risks. In health care, effective communication reduces the risk of error. Therefore, it is important to identify the predictive factors of effective communication. Non-technical skills are needed to achieve effective communication. This study explores how artificial neural networks can be applied to predict the risk of communication failures in emergency departments. A multicentre observational study. Data were collected between March-May 2011 by observing the communication interactions of 840 nurses with their patients during their routine activities in emergency departments. The tools used for our observation were a questionnaire to collect personal and descriptive data, level of training and experience and Guilbert's observation grid, applying the Situation-Background-Assessment-Recommendation technique to communication in emergency departments. A total of 840 observations were made on the nurses working in the emergency departments. Based on Guilbert's observation grid, the output variables is likely to influence the risk of communication failure were 'terminology'; 'listening'; 'attention' and 'clarity', whereas nurses' personal characteristics were used as input variables in the artificial neural network model. A model based on the multilayer perceptron topology was developed and trained. The receiver operator characteristic analysis confirmed that the artificial neural network model correctly predicted the performance of more than 80% of the communication failures. The application of the artificial neural network model could offer a valid tool to forecast and prevent harmful communication errors in the emergency department. © 2015 John Wiley & Sons Ltd.

Mesh Network Architecture for Enabling Inter-Spacecraft Communication

NASA Technical Reports Server (NTRS)

Becker, Christopher; Merrill, Garrick

2017-01-01

To enable communication between spacecraft operating in a formation or small constellation, a mesh network architecture was developed and tested using a time division multiple access (TDMA) communication scheme. The network is designed to allow for the exchange of telemetry and other data between spacecraft to enable collaboration between small spacecraft. The system uses a peer-to-peer topology with no central router, so that it does not have a single point of failure. The mesh network is dynamically configurable to allow for addition and subtraction of new spacecraft into the communication network. Flight testing was performed using an unmanned aerial system (UAS) formation acting as a spacecraft analogue and providing a stressing environment to prove mesh network performance. The mesh network was primarily devised to provide low latency, high frequency communication but is flexible and can also be configured to provide higher bandwidth for applications desiring high data throughput. The network includes a relay functionality that extends the maximum range between spacecraft in the network by relaying data from node to node. The mesh network control is implemented completely in software making it hardware agnostic, thereby allowing it to function with a wide variety of existing radios and computing platforms..

Minimizing communication cost among distributed controllers in software defined networks

NASA Astrophysics Data System (ADS)

Arlimatti, Shivaleela; Elbreiki, Walid; Hassan, Suhaidi; Habbal, Adib; Elshaikh, Mohamed

2016-08-01

Software Defined Networking (SDN) is a new paradigm to increase the flexibility of today's network by promising for a programmable network. The fundamental idea behind this new architecture is to simplify network complexity by decoupling control plane and data plane of the network devices, and by making the control plane centralized. Recently controllers have distributed to solve the problem of single point of failure, and to increase scalability and flexibility during workload distribution. Even though, controllers are flexible and scalable to accommodate more number of network switches, yet the problem of intercommunication cost between distributed controllers is still challenging issue in the Software Defined Network environment. This paper, aims to fill the gap by proposing a new mechanism, which minimizes intercommunication cost with graph partitioning algorithm, an NP hard problem. The methodology proposed in this paper is, swapping of network elements between controller domains to minimize communication cost by calculating communication gain. The swapping of elements minimizes inter and intra communication cost among network domains. We validate our work with the OMNeT++ simulation environment tool. Simulation results show that the proposed mechanism minimizes the inter domain communication cost among controllers compared to traditional distributed controllers.

Research Priorities in Networking and Communications.

ERIC Educational Resources Information Center

National Science Foundation, Washington, DC.

A workshop focused on major research issues in networking and communications. This report defines the context for research priorities and initiatives and deals with issues in networking and communications. Fifteen major research priorities and four research specific initiatives were identified by participants as areas that should be pursued over…

Communication Dynamics of Blog Networks

NASA Astrophysics Data System (ADS)

Goldberg, Mark; Kelley, Stephen; Magdon-Ismail, Malik; Mertsalov, Konstantin; Wallace, William (Al)

We study the communication dynamics of Blog networks, focusing on the Russian section of LiveJournal as a case study. Communication (blogger-to-blogger links) in such online communication networks is very dynamic: over 60% of the links in the network are new from one week to the next, though the set of bloggers remains approximately constant. Two fundamental questions are: (i) what models adequately describe such dynamic communication behavior; and (ii) how does one detect the phase transitions, i.e. the changes that go beyond the standard high-level dynamics? We approach these questions through the notion of stable statistics. We give strong experimental evidence to the fact that, despite the extreme amount of communication dynamics, several aggregate statistics are remarkably stable. We use stable statistics to test our models of communication dynamics postulating that any good model should produce values for these statistics which are both stable and close to the observed ones. Stable statistics can also be used to identify phase transitions, since any change in a normally stable statistic indicates a substantial change in the nature of the communication dynamics. We describe models of the communication dynamics in large social networks based on the principle of locality of communication: a node's communication energy is spent mostly within its own "social area," the locality of the node.

Time concurrency/phase-time synchronization in digital communications networks

NASA Technical Reports Server (NTRS)

Kihara, Masami; Imaoka, Atsushi

1990-01-01

Digital communications networks have the intrinsic capability of time synchronization which makes it possible for networks to supply time signals to some applications and services. A practical estimation method for the time concurrency on terrestrial networks is presented. By using this method, time concurrency capability of the Nippon Telegraph and Telephone Corporation (NTT) digital communications network is estimated to be better than 300 ns rms at an advanced level, and 20 ns rms at final level.

Network theory and its applications in economic systems

NASA Astrophysics Data System (ADS)

Huang, Xuqing

This dissertation covers the two major parts of my Ph.D. research: i) developing theoretical framework of complex networks; and ii) applying complex networks models to quantitatively analyze economics systems. In part I, we focus on developing theories of interdependent networks, which includes two chapters: 1) We develop a mathematical framework to study the percolation of interdependent networks under targeted-attack and find that when the highly connected nodes are protected and have lower probability to fail, in contrast to single scale-free (SF) networks where the percolation threshold pc = 0, coupled SF networks are significantly more vulnerable with pc significantly larger than zero. 2) We analytically demonstrates that clustering, which quantifies the propensity for two neighbors of the same vertex to also be neighbors of each other, significantly increases the vulnerability of the system. In part II, we apply the complex networks models to study economics systems, which also includes two chapters: 1) We study the US corporate governance network, in which nodes representing directors and links between two directors representing their service on common company boards, and propose a quantitative measure of information and influence transformation in the network. Thus we are able to identify the most influential directors in the network. 2) We propose a bipartite networks model to simulate the risk propagation process among commercial banks during financial crisis. With empirical bank's balance sheet data in 2007 as input to the model, we find that our model efficiently identifies a significant portion of the actual failed banks reported by Federal Deposit Insurance Corporation during the financial crisis between 2008 and 2011. The results suggest that complex networks model could be useful for systemic risk stress testing for financial systems. The model also identifies that commercial rather than residential real estate assets are major culprits for the failure of over 350 US commercial banks during 2008 - 2011.

Sexual health promotion in Chennai, India: key role of communication among social networks.

PubMed

Sivaram, Sudha; Johnson, Sethulakshmi; Bentley, Margaret E; Go, Vivian F; Latkin, Carl; Srikrishnan, A K; Celentano, David D; Solomon, Suniti

2005-12-01

Communication about sex and sexual health is an important facilitator in gaining accurate knowledge about prevention of sexually transmitted diseases (STDs) and promotion of sexual health. Understanding how and with whom communication about sex occurs and the nature of the information exchanged is valuable in designing sexual risk prevention interventions. In this study of low-income communities residents in Chennai, India, our aim was to understand the composition of personal communication networks, the nature of information related to sex and sexual health that is exchanged in these networks and the value of communication among members of these networks. We conducted in-depth open-ended interviews using a structured interview guide with 43 individuals. We also conducted 12 focus group discussions. Individuals were selected using snowball sampling. Our results indicate that information about sex and sexual health is exchanged within and between four groups: married women, married men, unmarried men and unmarried women. Communication leads to an expansion of sexual networks among unmarried men and treatment seeking behaviour for STDs in all groups. Unmarried men offer immense potential for intervention given the range of topics related to sex and sexual health that are discussed and the risky sexual behaviours practiced. Spousal communication about sexual behaviour or sexual health is minimal and shifting norms for prevention would be difficult. Interventions identifying communication networks and influencing the natural communication patterns in these networks may be a viable HIV prevention strategy in the study area.

Population-level preferences for primary care physicians' characteristics in Japan: a structural equation modeling.

PubMed

Takahashi, Osamu; Ohde, Sachiko; Jacobs, Joshua L; Tokuda, Yasuharu; Yanai, Haruo; Okubo, Tomoya; Shimbo, Takuro; Fukuhara, Shunichi; Hinohara, Shigeaki; Fukui, Tsuguya

2010-01-01

Primary care has potential to play a role for improving the patient care in Japanese health care system; however, little information is available about how patients perceive the roles of primary care physicians (PCPs) within the Japanese health care system. We aimed to assess population-level preferences for PCPs and investigated the extent to which preferences vary in relation to different population groups in Japan. Data were extracted from a cross-sectional questionnaire survey in October 2003. An 18-item questionnaire was used to measure the preferences for PCPs. Exploratory factor analysis was performed to identify latent factors, while confirmatory factor analysis was used to evaluate the fit of the structure using structural equation modeling (SEM). Nationally representative sample of the adult Japanese general population was chosen by controlling for age, sex, and the size of cities. A total of 2,453 adults>or=18-years-old were analyzed. SEM provided a 4-factor structural model of the population-level preference for PCPs, such as clinical competence (path coefficient (pc)=0.72), gate-keeping (pc=0.64), communication with patients or specialists (pc=0.49) and high education (pc=0.25) and demonstrated the best goodness-of-fit. Those who were middle aged, have a high family income, and a high level of education, placed more importance on gate-keeping characteristics, and the rural residents emphasized communication rather than clinical competence. Our results indicate that the preferences for PCPs are divided into four main factors and underscore the variation among preferences according to different population groups, such as age, socioeconomic and educational status, and places of living. These variations should be considered to improve the primary care system in Japan.

Palliative care consultation in the process of organ donation after cardiac death.

PubMed

Kelso, Catherine McVearry; Lyckholm, Laurie J; Coyne, Patrick J; Smith, Thomas J

2007-02-01

Palliative care consultation has been demonstrated to be useful in many situations in which expert symptom management, communication around sensitive issues, and family support may serve to enhance or improve care. The process of organ donation is an example of this concept, specifically the process of donation after cardiac death (DCD). DCD allows patients with severe, irreversible brain injuries that do not meet standard criteria for brain death to donate organs when death is declared by cardiopulmonary criteria. The DCD method of donation has been deemed an ethically appropriate means of organ donation and is supported by the organ procurement and medical communities, as well as the public. The palliative care (PC) team can make a significant contribution to the care of the patient and family in the organ donation process. In this paper we describe the controlled DCD process at one institution that utilizes the PC team to provide expert end-of-life care, including comprehensive medical management and family support. PC skills and principles applicable to the DCD process include communication, coordination of care, and skillful ventilator withdrawal. If death occurs within 90 minutes of withdrawal of life support, organs may be successfully recovered for transplantation. If the patient survives longer than 90 minutes, his or her care continues to be provided by the PC team. Palliative care can contribute to standardizing quality end-of-life care practices in the DCD process and provide education for involved personnel. Further experience, research and national discussions will be helpful in refining these practices, to make this difficult and challenging experience as gentle and supportive as possible for the courageous families who participate in this process.

In-Space Internet-Based Communications for Space Science Platforms Using Commercial Satellite Networks

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.; Bhasin, Kul B.; Fabian, Theodore P.; Griner, James H.; Kachmar, Brian A.; Richard, Alan M.

1999-01-01

The continuing technological advances in satellite communications and global networking have resulted in commercial systems that now can potentially provide capabilities for communications with space-based science platforms. This reduces the need for expensive government owned communications infrastructures to support space science missions while simultaneously making available better service to the end users. An interactive, high data rate Internet type connection through commercial space communications networks would enable authorized researchers anywhere to control space-based experiments in near real time and obtain experimental results immediately. A space based communications network architecture consisting of satellite constellations connecting orbiting space science platforms to ground users can be developed to provide this service. The unresolved technical issues presented by this scenario are the subject of research at NASA's Glenn Research Center in Cleveland, Ohio. Assessment of network architectures, identification of required new or improved technologies, and investigation of data communications protocols are being performed through testbed and satellite experiments and laboratory simulations.

Hyper-Spectral Communications, Networking and ATM as Foundation for Safe and Efficient Future Flight: Transcending Aviation Operational Limitations with Diverse and Secure Multi-Band, Multi-Mode, and mmWave Wireless Links: Project Overview, Aviation Communications and New Signaling

NASA Technical Reports Server (NTRS)

Matolak, David W.

2017-01-01

NASA's Aeronautics Research Mission Directorate (ARMD) has recently solicited proposals and awarded funds for research and development to achieve and exceed the goals envisioned in the ARMD Strategic Implementation Plan (SIP). The Hyper-Spectral Communications and Networking for Air Traffic Management (ATM) (HSCNA) project is the only University Leadership Initiative (ULI) program to address communications and networking (and to a degree, navigation and surveillance). This paper will provide an overview of the HSCNA project, and specifically describe two of the project's technical challenges: comprehensive aviation communications and networking assessment, and proposed multi-band and multimode communications and networking. The primary goals will be described, as will be research and development aimed to achieve and exceed these goals. Some example initial results are also provided.

Robust and Cost-Efficient Communication Based on SNMP in Mobile Networks

NASA Astrophysics Data System (ADS)

Ryu, Sang-Hoon; Baik, Doo-Kwon

A main challenge in the design of this mobile network is the development of dynamic routing protocols that can efficiently find routes between two communicating nodes. Multimedia streaming services are receiving considerable interest in the mobile network business. An entire mobile network may change its point of attachment to the Internet. The mobile network is operated by a basic specification to support network mobility called Network Mobility (NEMO) Basic Support. However, NEMO basic Support mechanism has some problem in continuous communication. In this paper, we propose robust and cost-efficient algorithm. And we simulate proposed method and conclude some remarks.

75 FR 34459 - Converged Communications and Health Care Devices Impact on Regulation; Public Meeting; Request...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-17

... established commercial communications networks such as Internet connectivity to communicate with care... stimulate muscle movement. Examples of devices and applications that use commercial communications networks...] Converged Communications and Health Care Devices Impact on Regulation; Public Meeting; Request for Comments...

Single-shot secure quantum network coding on butterfly network with free public communication

NASA Astrophysics Data System (ADS)

Owari, Masaki; Kato, Go; Hayashi, Masahito

2018-01-01

Quantum network coding on the butterfly network has been studied as a typical example of quantum multiple cast network. We propose a secure quantum network code for the butterfly network with free public classical communication in the multiple unicast setting under restricted eavesdropper’s power. This protocol certainly transmits quantum states when there is no attack. We also show the secrecy with shared randomness as additional resource when the eavesdropper wiretaps one of the channels in the butterfly network and also derives the information sending through public classical communication. Our protocol does not require verification process, which ensures single-shot security.

SBIR Technology Applications to Space Communications and Navigation (SCaN)

NASA Technical Reports Server (NTRS)

Liebrecht, Phil; Eblen, Pat; Rush, John; Tzinis, Irene

2010-01-01

This slide presentation reviews the mission of the Space Communications and Navigation (SCaN) Office with particular emphasis on opportunities for technology development with SBIR companies. The SCaN office manages NASA's space communications and navigation networks: the Near Earth Network (NEN), the Space Network (SN), and the Deep Space Network (DSN). The SCaN networks nodes are shown on a world wide map and the networks are described. Two types of technologies are described: Pull technology, and Push technologies. A listing of technology themes is presented, with a discussion on Software defined Radios, Optical Communications Technology, and Lunar Lasercom Space Terminal (LLST). Other technologies that are being investigated are some Game Changing Technologies (GCT) i.e., technologies that offer the potential for improving comm. or nav. performance to the point that radical new mission objectives are possible, such as Superconducting Quantum Interference Filters, Silicon Nanowire Optical Detectors, and Auto-Configuring Cognitive Communications

Measurement and Control System Based on Wireless Senor Network for Granary

NASA Astrophysics Data System (ADS)

Song, Jian

A wireless measurement and control system for granary is developed for the sake of overcoming the shortcoming of the wired measurement and control system such as complex wiring and low anti-interference capacity. In this system, Zigbee technology is applied with Zigbee protocol stack development platform by TI, and wireless senor network is used to collect and control the temperature and the humidity. It is composed of the upper PC, central control node based on CC2530, sensor nodes, sensor modules and the executive device. The wireless sensor node is programmed by C language in IAR Embedded Workbench for MCS-51 Evaluation environment. The upper PC control system software is developed based on Visual C++ 6.0 platform. It is shown by experiments that data transmission in the system is accurate and reliable and the error of the temperature and humidity is below 2%, meeting the functional requirements for the granary measurement and control system.

Network Coding in Relay-based Device-to-Device Communications

PubMed Central

Huang, Jun; Gharavi, Hamid; Yan, Huifang; Xing, Cong-cong

2018-01-01

Device-to-Device (D2D) communications has been realized as an effective means to improve network throughput, reduce transmission latency, and extend cellular coverage in 5G systems. Network coding is a well-established technique known for its capability to reduce the number of retransmissions. In this article, we review state-of-the-art network coding in relay-based D2D communications, in terms of application scenarios and network coding techniques. We then apply two representative network coding techniques to dual-hop D2D communications and present an efficient relay node selecting mechanism as a case study. We also outline potential future research directions, according to the current research challenges. Our intention is to provide researchers and practitioners with a comprehensive overview of the current research status in this area and hope that this article may motivate more researchers to participate in developing network coding techniques for different relay-based D2D communications scenarios. PMID:29503504

Propeptides are sufficient to regulate organelle-specific pH-dependent activation of furin and proprotein convertase 1/3.

PubMed

Dillon, Stephanie L; Williamson, Danielle M; Elferich, Johannes; Radler, David; Joshi, Rajendra; Thomas, Gary; Shinde, Ujwal

2012-10-12

The proprotein convertases (PCs) furin and proprotein convertase 1/3 (PC1) cleave substrates at dibasic residues along the eukaryotic secretory/endocytic pathway. PCs are evolutionarily related to bacterial subtilisin and are synthesized as zymogens. They contain N-terminal propeptides (PRO) that function as dedicated catalysts that facilitate folding and regulate activation of cognate proteases through multiple-ordered cleavages. Previous studies identified a histidine residue (His69) that functions as a pH sensor in the propeptide of furin (PRO(FUR)), which regulates furin activation at pH~6.5 within the trans-Golgi network. Although this residue is conserved in the PC1 propeptide (PRO(PC1)), PC1 nonetheless activates at pH~5.5 within the dense core secretory granules. Here, we analyze the mechanism by which PRO(FUR) regulates furin activation and examine why PRO(FUR) and PRO(PC1) differ in their pH-dependent activation. Sequence analyses establish that while both PRO(FUR) and PRO(PC1) are enriched in histidines when compared with cognate catalytic domains and prokaryotic orthologs, histidine content in PRO(FUR) is ~2-fold greater than that in PRO(PC1), which may augment its pH sensitivity. Spectroscopy and molecular dynamics establish that histidine protonation significantly unfolds PRO(FUR) when compared to PRO(PC1) to enhance autoproteolysis. We further demonstrate that PRO(FUR) and PRO(PC1) are sufficient to confer organelle sensing on folding and activation of their cognate proteases. Swapping propeptides between furin and PC1 transfers pH-dependent protease activation in a propeptide-dictated manner in vitro and in cells. Since prokaryotes lack organelles and eukaryotic PCs evolved from propeptide-dependent, not propeptide-independent prokaryotic subtilases, our results suggest that histidine enrichment may have enabled propeptides to evolve to exploit pH gradients to activate within specific organelles. Copyright © 2012 Elsevier Ltd. All rights reserved.

47 CFR 11.20 - State Relay Network.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 1 2011-10-01 2011-10-01 false State Relay Network. 11.20 Section 11.20... Network. This network is composed of State Relay (SR) sources, leased common carrier communications facilities or any other available communication facilities. The network distributes State EAS messages...

47 CFR 11.20 - State Relay Network.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false State Relay Network. 11.20 Section 11.20... Network. This network is composed of State Relay (SR) sources, leased common carrier communications facilities or any other available communication facilities. The network distributes State EAS messages...

Intercultural Communication in Online Social Networking Discourse

ERIC Educational Resources Information Center

Chen, Hsin-I

2017-01-01

This article presents a case study that examines how an online social networking community is constituted through intercultural discourse on the part of one learner sojourning in the US. Using Byram's model of intercultural communicative competence, this study examines the learner's naturalistic communication in a social networking site (SNS). The…

The Effectiveness of Using Social Communications Networks in Mathematics Teachers' Professional Development

ERIC Educational Resources Information Center

Hussein, Hisham Barakat

2013-01-01

The study aims to determine the effectiveness of using social communications networks in mathematics teachers' professional development. The main research questions was: what is the effectiveness of using social communications networks in mathematics teachers' professional development. The sub questions were: (1) what are the standards of…

Future communications satellite applications

NASA Technical Reports Server (NTRS)

Bagwell, James W.

1992-01-01

The point of view of the research is made through the use of viewgraphs. It is suggested that future communications satellite applications will be made through switched point to point narrowband communications. Some characteristics of which are as follows: small/low cost terminals; single hop communications; voice compatible; full mesh networking; ISDN compatible; and possible limited use of full motion video. Some target applications are as follows: voice/data networks between plants and offices in a corporation; data base networking for commercial and science users; and cellular radio internodal voice/data networking.

Research on TCP/IP network communication based on Node.js

NASA Astrophysics Data System (ADS)

Huang, Jing; Cai, Lixiong

2018-04-01

In the face of big data, long connection and high synchronization, TCP/IP network communication will cause performance bottlenecks due to its blocking multi-threading service model. This paper presents a method of TCP/IP network communication protocol based on Node.js. On the basis of analyzing the characteristics of Node.js architecture and asynchronous non-blocking I/O model, the principle of its efficiency is discussed, and then compare and analyze the network communication model of TCP/IP protocol to expound the reasons why TCP/IP protocol stack is widely used in network communication. Finally, according to the large data and high concurrency in the large-scale grape growing environment monitoring process, a TCP server design based on Node.js is completed. The results show that the example runs stably and efficiently.

Research of the key technology in satellite communication networks

NASA Astrophysics Data System (ADS)

Zeng, Yuan

2018-02-01

According to the prediction, in the next 10 years the wireless data traffic will be increased by 500-1000 times. Not only the wireless data traffic will be increased exponentially, and the demand for diversified traffic will be increased. Higher requirements for future mobile wireless communication system had brought huge market space for satellite communication system. At the same time, the space information networks had been greatly developed with the depth of human exploration of space activities, the development of space application, the expansion of military and civilian application. The core of spatial information networks is the satellite communication. The dissertation presented the communication system architecture, the communication protocol, the routing strategy, switch scheduling algorithm and the handoff strategy based on the satellite communication system. We built the simulation platform of the LEO satellites networks and simulated the key technology using OPNET.

AIDS communications through social networks: catalyst for behaviour changes in Uganda.

PubMed

Low-Beer, Daniel; Stoneburner, Rand L

2004-05-01

To investigate distinctive communications through social networks which may be associated with population behaviour changes and HIV prevalence declines in Uganda compared to other countries. We undertook a comparative analysis of demographic and HIV behavioural data collected in Demographic and Health Surveys (DHS III) in Uganda, Kenya, Tanzania, Malawi, Zambia and Zimbabwe as well as Knowledge, Attitudes and Behaviours (KABP) surveys in Uganda in 1989 and 1995. AIDS behaviours, social communications and channels for communication about AIDS and people with AIDS were analysed by age, sex and country. Modelling was developed to investigate at what stage of the epidemic a majority of people will know someone with AIDS, given differing communication patterns through social networks. Finally AIDS reporting and Voluntary Counselling and Testing (VCT) trends were analysed to assess if the impact of social communications worked through clinical services and interventions or more directly at the population level in community contexts. Uganda showed unique patterns of communications through social networks including a shift from mass and institutional to personal channels for communicating about AIDS, 1989-1995. This was associated with higher levels of knowing someone with AIDS through social networks and, in turn, positive risk ratios for behaviour change including reducing casual sex and condom use. Youth had distinctively high levels of knowing someone with AIDS in Uganda, suggesting widespread community communication across age groups. Patterns of disclosure, AIDS diagnosis and reporting were influential on social communications about AIDS. Over 90%, 45% or under 20% of people know someone with AIDS at peak HIV incidence and high AIDS mortality, depending on whether communications through social networks are extensive or restricted. There are distinctive patterns for communicating through social networks about AIDS and people with AIDS in Uganda. They appear to work directly at population level rather than in response to clinical interventions and testing and may be important in the uptake of the latter services. This communication response provides an important basis for HIV prevention if it is to be scaled to the population level. Vertical prevention (and even treatment) interventions need to engage more closely with local, horizontal communication and behavioural responses to AIDS. Communication programmes have to take root at the level of social networks working though local networks of meetings, chiefs, churches and health personnel as well as the media. Mobilising basic social communications may be a necessary resource (as much as services and finance) to scale HIV prevention and treatment to the population level.

The deep space network, volume 18. [Deep Space Instrumentation Facility, Ground Communication Facility, and Network Control System

NASA Technical Reports Server (NTRS)

1973-01-01

The objectives, functions, and organization of the Deep Space Network are summarized. The Deep Space Instrumentation Facility, the Ground Communications Facility, and the Network Control System are described.

Channel Efficiency with Security Enhancement for Remote Condition Monitoring of Multi Machine System Using Hybrid Huffman Coding

NASA Astrophysics Data System (ADS)

Datta, Jinia; Chowdhuri, Sumana; Bera, Jitendranath

2016-12-01

This paper presents a novel scheme of remote condition monitoring of multi machine system where a secured and coded data of induction machine with different parameters is communicated between a state-of-the-art dedicated hardware Units (DHU) installed at the machine terminal and a centralized PC based machine data management (MDM) software. The DHUs are built for acquisition of different parameters from the respective machines, and hence are placed at their nearby panels in order to acquire different parameters cost effectively during their running condition. The MDM software collects these data through a communication channel where all the DHUs are networked using RS485 protocol. Before transmitting, the parameter's related data is modified with the adoption of differential pulse coded modulation (DPCM) and Huffman coding technique. It is further encrypted with a private key where different keys are used for different DHUs. In this way a data security scheme is adopted during its passage through the communication channel in order to avoid any third party attack into the channel. The hybrid mode of DPCM and Huffman coding is chosen to reduce the data packet length. A MATLAB based simulation and its practical implementation using DHUs at three machine terminals (one healthy three phase, one healthy single phase and one faulty three phase machine) proves its efficacy and usefulness for condition based maintenance of multi machine system. The data at the central control room are decrypted and decoded using MDM software. In this work it is observed that Chanel efficiency with respect to different parameter measurements has been increased very much.

Shared decision-making in older patients with colorectal or pancreatic cancer: Determinants of patients' and observers' perceptions.

PubMed

Geessink, Noralie H; Ofstad, Eirik H; Olde Rikkert, Marcel G M; van Goor, Harry; Kasper, Jürgen; Schoon, Yvonne

2018-06-13

To identify determinants of older patients' perceptions of involvement in decision-making on colorectal (CRC) or pancreatic cancer (PC) treatment, and to compare these with determinants of observers' perceptions. Patients' perceptions of involvement were constructed by the 9-item SDM questionnaire (SDM-Q-9) and a Visual Analogue Scale for Involvement (VAS-I). Observers' perceptions were constructed by the OPTION5, OPTION12, and MAPPIN'SDM. Convergent validities were calculated between the patient-sided and observer instruments using Spearman's correlation coefficient. Linear regression was used to identify determinants per criterion. 58 CRC and 22 PC patients were included (mean age: 71.8 ± 5.2 years, 45.0% female). No significant correlations were found between the patient-sided and observer instruments. Patients' impression of involvement was influenced by patient characteristics such as quality of life and satisfaction, while observers' perceptions mainly referred to encounter characteristics such as the mean duration of consultations and general communication skills. Due to evident differences in determinants, older CRC/PC patients' and observers' perceptions of involvement should both be collected in evaluating the quality of medical decision-making. General communication skills should be integrated in SDM training interventions. New SDM measurement tools for patients are needed to sufficiently discriminate between the constructs of involvement and satisfaction. Copyright © 2018 Elsevier B.V. All rights reserved.

Small satellite space operations

NASA Technical Reports Server (NTRS)

Reiss, Keith

1994-01-01

CTA Space Systems has played a premier role in the development of the 'lightsat' programs of the 80's and 90's. The high costs and development times associated with conventional LEO satellite design, fabrication, launch, and operations continue to motivate the development of new methodologies, techniques, and generally low cost and less stringently regulated satellites. These spacecraft employ low power 'lightsat' communications (versus TDRSS for NASA's LEO's) and typically fly missions with payload/experiment suites that can succeed, for example, without heavily redundant backup systems and large infrastructures of personnel and ground support systems. Such small yet adaptable satellites are also typified by their very short contract-to-launch times (often one to two years). This paper reflects several of the methodologies and perspectives of our successful involvement in these innovative programs and suggests how they might relieve NASA's mounting pressures to reduce the cost of both the spacecraft and their companion mission operations. It focuses on the use of adaptable, sufficiently powerful yet inexpensive PC-based ground systems for wide ranging user terminal (UT) applications and master control facilities for mission operations. These systems proved themselves in successfully controlling more than two dozen USAF, USN, and ARPA satellites at CTA/SS. UT versions have linked with both GEO and LEO satellites and functioned autonomously in relay roles often in remote parts of the world. LEO applications particularly illustrate the efficacy of these concepts since a user can easily mount a lightweight antenna, usually an omni or helix with light duty rotors and PC-based drivers. A few feet of coax connected to a small transceiver module (the size of a small PC) and a serial line to an associated PC establishes a communications link and together with the PC constitute a viable ground station. Applications included geomagnetic mapping; spaceborne solid state recorder validation; global store-and-forward data communications for both scientific and military purposes such as Desert Storm; UHF transponder services for both digital data and voice using a constellation; remote sensor monitoring of weather and oceanographic conditions; classified payloads; and UHF spectrum surveillance. Ground processing has been accomplished by automatic unattended or manual operation. Management of multiple assets highlights the relative ease with which two constellations totaling nine satellites were controlled from one system including constellation station keeping. Our experience in small end-to-end systems including concurrent design, development, and testing of the flight and operational ground systems offers low cost approaches to NASA scientific satellite operations of the 1990's.

Task five report: Laser communications for data acquisition networks. [characteristics of lasers and laser systems for optical communication applications

NASA Technical Reports Server (NTRS)

1973-01-01

Laser communication technology and laser communication performance are reviewed. The subjects discussed are: (1) characteristics of laser communication systems, (2) laser technology problems, (3) means of overcoming laser technology problems, and (4) potential schedule for including laser communications into data acquisition networks. Various types of laser communication systems are described and their capabilities are defined.

Challenges of Integrating NASA's Space Communications Networks

NASA Technical Reports Server (NTRS)

Reinert, Jessica; Barnes, Patrick

2013-01-01

The transition to new technology, innovative ideas, and resistance to change is something that every industry experiences. Recent examples of this shift are changing to using robots in the assembly line construction of automobiles or the increasing use of robotics for medical procedures. Most often this is done with cost-reduction in mind, though ease of use for the customer is also a driver. All industries experience the push to increase efficiency of their systems; National Aeronautics and Space Administration (NASA) and the commercial space industry are no different. NASA space communication services are provided by three separately designed, developed, maintained, and operated communications networks known as the Deep Space Network (DSN), Near Earth Network (NEN) and Space Network (SN). The Space Communications and Navigation (SCaN) Program is pursuing integration of these networks and has performed a variety of architecture trade studies to determine what integration options would be the most effective in achieving a unified user mission support organization, and increase the use of common operational equipment and processes. The integration of multiple, legacy organizations and existing systems has challenges ranging from technical to cultural. The existing networks are the progeny of the very first communication and tracking capabilities implemented by NASA and the Jet Propulsion Laboratory (JPL) more than 50 years ago and have been customized to the needs of their respective user mission base. The technical challenges to integrating the networks are many, though not impossible to overcome. The three distinct networks provide the same types of services, with customizable data rates, bandwidth, frequencies, and so forth. The differences across the networks have occurred in effort to satisfy their user missions' needs. Each new requirement has made the networks more unique and harder to integrate. The cultural challenges, however, have proven to be a significant obstacle for integration. Over the past few decades of use, user missions and network personnel alike have grown accustomed to the processes by which services are provided by the NASA communications and navigation networks. The culture established by each network has created several challenges that need to be overcome in order to effectively integrate the networks. As with any change, there has been resistance, an apprehension to explore automation of existing processes, and a working environment that attempts to indirectly influence change without mandating compliance. Overcoming technical and cultural challenges is essential to successfully integrating the networks and although the challenges are numerous, the integration of the networks promises a more efficient space communications network for NASA and its customers, as well as potential long-term cost savings to the agency. This paper, Challenges of Integrating NASA Legacy Communications Networks, will provide a brief overview of the current NASA space communications networks as well as the an overview of the process implemented while performing the SCaN Trade Studies and an introduction to the requirements driving integration of the SCaN Networks. This paper will describe in detail the challenges experienced, both technical and cultural, while working with NASA space communications network-specific personnel. The paper will also cover lessons learned during the performance of architecture trade studies and provide recommendations for ways to improve the process.

Challenges of Integrating NASAs Space Communication Networks

NASA Technical Reports Server (NTRS)

Reinert, Jessica M.; Barnes, Patrick

2013-01-01

The transition to new technology, innovative ideas, and resistance to change is something that every industry experiences. Recent examples of this shift are changing to using robots in the assembly line construction of automobiles or the increasing use of robotics for medical procedures. Most often this is done with cost-reduction in mind, though ease of use for the customer is also a driver. All industries experience the push to increase efficiency of their systems; National Aeronautics and Space Administration (NASA) and the commercial space industry are no different. NASA space communication services are provided by three separately designed, developed, maintained, and operated communications networks known as the Deep Space Network (DSN), Near Earth Network (NEN) and Space Network (SN). The Space Communications and Navigation (SCaN) Program is pursuing integration of these networks and has performed a variety of architecture trade studies to determine what integration options would be the most effective in achieving a unified user mission support organization, and increase the use of common operational equipment and processes. The integration of multiple, legacy organizations and existing systems has challenges ranging from technical to cultural. The existing networks are the progeny of the very first communication and tracking capabilities implemented by NASA and the Jet Propulsion Laboratory (JPL) more than 50 years ago and have been customized to the needs of their respective user mission base. The technical challenges to integrating the networks are many, though not impossible to overcome. The three distinct networks provide the same types of services, with customizable data rates, bandwidth, frequencies, and so forth. The differences across the networks have occurred in effort to satisfy their user missions' needs. Each new requirement has made the networks more unique and harder to integrate. The cultural challenges, however, have proven to be a significant obstacle for integration. Over the past few decades of use, user missions and network personnel alike have grown accustomed to the processes by which services are provided by the NASA communications and navigation networks. The culture established by each network has created several challenges that need to be overcome in order to effectively integrate the networks. As with any change, there has been resistance, an apprehension to explore automation of existing processes, and a working environment that attempts to indirectly influence change without mandating compliance. Overcoming technical and cultural challenges is essential to successfully integrating the networks and although the challenges are numerous, the integration of the networks promises a more efficient space communications network for NASA and its customers, as well as potential long-term cost savings to the agency. This paper, Challenges of Integrating NASA Legacy Communications Networks, will provide a brief overview of the current NASA space communications networks as well as the an overview of the process implemented while performing the SCaN Trade Studies and an introduction to the requirements driving integration of the SCaN Networks. This paper will describe in detail the challenges experienced, both technical and cultural, while working with NASA space communications network-specific personnel. The paper will also cover lessons learned during the performance of architecture trade studies and provide recommendations for ways to improve the process.

A performance study of unmanned aerial vehicle-based sensor networks under cyber attack

NASA Astrophysics Data System (ADS)

Puchaty, Ethan M.

In UAV-based sensor networks, an emerging area of interest is the performance of these networks under cyber attack. This study seeks to evaluate the performance trade-offs from a System-of-Systems (SoS) perspective between various UAV communications architecture options in the context two missions: tracking ballistic missiles and tracking insurgents. An agent-based discrete event simulation is used to model a sensor communication network consisting of UAVs, military communications satellites, ground relay stations, and a mission control center. Network susceptibility to cyber attack is modeled with probabilistic failures and induced data variability, with performance metrics focusing on information availability, latency, and trustworthiness. Results demonstrated that using UAVs as routers increased network availability with a minimal latency penalty and communications satellite networks were best for long distance operations. Redundancy in the number of links between communication nodes helped mitigate cyber-caused link failures and add robustness in cases of induced data variability by an adversary. However, when failures were not independent, redundancy and UAV routing were detrimental in some cases to network performance. Sensitivity studies indicated that long cyber-caused downtimes and increasing failure dependencies resulted in build-ups of failures and caused significant degradations in network performance.

The Network Classroom.

ERIC Educational Resources Information Center

Maule, R. William

1993-01-01

Discussion of the role of new computer communications technologies in education focuses on modern networking systems, including fiber distributed data interface and Integrated Services Digital Network; strategies for implementing networked-based communication; and public online information resources for the classroom, including Bitnet, Internet,…

GATEWAY - COMMUNICATIONS GATEWAY SOFTWARE FOR NETEX, DECNET, AND TCP/IP

NASA Technical Reports Server (NTRS)

Keith, B.

1994-01-01

The Communications Gateway Software, GATEWAY, provides process-to-process communication between remote applications programs in different protocol domains. Communicating peer processes may be resident on any paired combination of NETEX, DECnet, or TCP/IP hosts. The gateway provides the necessary mapping from one protocol to another and will facilitate practical intermachine communications in a cost effective manner by eliminating the need to standardize on a single protocol or the need to implement multiple protocols in the host computers. The purpose of the gateway is to support data transfers between application programs on different host computers using different protocols. The gateway computer must be physically connected to both host computers and must contain the system software needed to use the communication protocols of both host computers. The communication process between application partners can be divided into three phases: session establishment, data transfer, and session termination. The communication protocols supported by GATEWAY (DECnet, NETEX, and TCP/IP) have addressing mechanisms that allow an application to identify itself and distinguish among other applications on the network. The exact form of the address varies depending on whether an application is passively offering (awaiting the receipt of a network connection from another network application) or actively connecting to another network. When the gateway is started, GATEWAY reads a file of address pairs. One of the address pairs is used by GATEWAY for passively offering on one network while the other address in the pair is used for actively connecting on the other network establishing the session. Now the two application partners can send and receive data in a manner appropriate to their home networks. GATEWAY accommodates full duplex transmissions. Thus, if the application partners are sophisticated enough, they can send and receive simultaneously. GATEWAY also keeps track of the number of bytes contained in each ransferred data packet. If GATEWAY detects an error during the data transfer, the sessions on both networks are terminated and the passive offer on the appropriate network is reissued. After performing the desired data transfer, one of the remote applications will send a network disconnect to the gateway to close its communication link. Upon detecting this network disconnect, GATEWAY replies with its own disconnect to ensure that the network connection has been fully terminated. Then, GATEWAY terminates its session with the other application by closing the communication link. GATEWAY has been implemented on a DEC VAX under VMS 4.7. It is written in ADA and has a central memory requirement of approximately 406K bytes. The communications protocols supported by GATEWAY are Network Systems Corporation's Network Executive (NETEX), Excelan's TCP/IP, and DECnet. GATEWAY was developed in 1988.

The impact of Polycomb group (PcG) and Trithorax group (TrxG) epigenetic factors in plant plasticity.

PubMed

de la Paz Sanchez, Maria; Aceves-García, Pamela; Petrone, Emilio; Steckenborn, Stefan; Vega-León, Rosario; Álvarez-Buylla, Elena R; Garay-Arroyo, Adriana; García-Ponce, Berenice

2015-11-01

Current advances indicate that epigenetic mechanisms play important roles in the regulatory networks involved in plant developmental responses to environmental conditions. Hence, understanding the role of such components becomes crucial to understanding the mechanisms underlying the plasticity and variability of plant traits, and thus the ecology and evolution of plant development. We now know that important components of phenotypic variation may result from heritable and reversible epigenetic mechanisms without genetic alterations. The epigenetic factors Polycomb group (PcG) and Trithorax group (TrxG) are involved in developmental processes that respond to environmental signals, playing important roles in plant plasticity. In this review, we discuss current knowledge of TrxG and PcG functions in different developmental processes in response to internal and environmental cues and we also integrate the emerging evidence concerning their function in plant plasticity. Many such plastic responses rely on meristematic cell behavior, including stem cell niche maintenance, cellular reprogramming, flowering and dormancy as well as stress memory. This information will help to determine how to integrate the role of epigenetic regulation into models of gene regulatory networks, which have mostly included transcriptional interactions underlying various aspects of plant development and its plastic response to environmental conditions. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

A Solid-State Intrinsically Stretchable Polymer Solar Cell.

PubMed

Li, Lu; Liang, Jiajie; Gao, Huier; Li, Ying; Niu, Xiaofan; Zhu, Xiaodan; Xiong, Yan; Pei, Qibing

2017-11-22

An organic solar cell based on a bulk heterojunction of a conjugated polymer and a methanofullerene PC 61 BM or PC 71 BM exhibits a complex morphology that controls both its photovoltaic and mechanical compliance (flexibility and stretchability). Here, the donor-acceptor blend of poly(thieno[3,4-b]-thiophene/benzodithiophene) (PTB7) and PC 71 BM containing a small amount of diiodooctane (DIO) in the spin-casting solution is reported to exhibit elastic deformability. The blend comprises nanometer-size, nanocrystalline grains that are relatively uniformly distributed. Large external deformation is accommodated by relative sliding between the grains. Reorientation of the nanocrystallites and the global reorientation of the PTB7 polymer chain were observed along the stretching direction up to 100% strain, which was reversible as the blend was allowed to relax to 0% strain. The polymer solar cell based on PTB7:PC 71 BM:DIO with such reversible morphological changes exhibited a rubbery elasticity at room temperature. The device could be stretched up to 100% strain, and the power-conversion efficiency shows a slight increase up to 30% strain and a global increase of power generation as the photoactive area increases with strain. Solar cells were fabricated employing a layer of the PTB7:PC 71 BM:DIO blend sandwiched between a pair of stretchable transparent electrodes, each comprising a stack of a silver nanowire percolation network and a single-wall carbon nanotube network embedded in the surface of a poly(urethane acylate) elastomer film. The solar cells were semitransparent and could be stretched like a rubbery film by as much as 100% strain. The measured power-conversion efficiency was 3.48%, which was increased to 3.67% after one cycle of stretching to 50% strain and lowered to 2.99% after 100 stretching cycles. The total power generation from the cells was significantly increased, thanks to the expanded active area as the cells were stretched.

Molecular inspired models for prediction and control of directional FSO/RF wireless networks

NASA Astrophysics Data System (ADS)

Llorca, Jaime; Milner, Stuart D.; Davis, Christopher C.

2010-08-01

Directional wireless networks using FSO and RF transmissions provide wireless backbone support for mobile communications in dynamic environments. The heterogeneous and dynamic nature of such networks challenges their robustness and requires self-organization mechanisms to assure end-to-end broadband connectivity. We developed a framework based on the definition of a potential energy function to characterize robustness in communication networks and the study of first and second order variations of the potential energy to provide prediction and control strategies for network performance optimization. In this paper, we present non-convex molecular potentials such as the Morse Potential, used to describe the potential energy of bonds within molecules, for the characterization of communication links in the presence of physical constraints such as the power available at the network nodes. The inclusion of the Morse Potential translates into adaptive control strategies where forces on network nodes drive the release, retention or reconfiguration of communication links for network performance optimization. Simulation results show the effectiveness of our self-organized control mechanism, where the physical topology reorganizes to maximize the number of source to destination communicating pairs. Molecular Normal Mode Analysis (NMA) techniques for assessing network performance degradation in dynamic networks are also presented. Preliminary results show correlation between peaks in the eigenvalues of the Hessian of the network potential and network degradation.

Open Radio Communications Architecture Core Framework V1.1.0 Volume 1 Software Users Manual

DTIC Science & Technology

2005-02-01

on a PC utilizing the KDE desktop that comes with Red Hat Linux . The default desktop for most Red Hat Linux installations is the GNOME desktop. The...SCA) v2.2. The software was designed for a desktop computer running the Linux operating system (OS). It was developed in C++, uses ACE/TAO for CORBA...middleware, Xerces for the XML parser, and Red Hat Linux for the Operating System. The software is referred to as, Open Radio Communication

Communication Network Design: West Ottawa School District.

ERIC Educational Resources Information Center

Couch, David deS.

This report describes the technical details and rationale behind the decisions in the design and development of the communications network installed as part of a 1991-1993 district-wide construction project in the West Ottawa Public Schools (Michigan). The project called for development of a communications network to carry voice, data, and video…

Electromagnetic interference of power conditioners for solar electric propulsion

NASA Technical Reports Server (NTRS)

Whittlesey, A. C.; Macie, T. W.

1973-01-01

Electrical, multikilowatt power conditioning (PC) equipment needed on board a spacecraft utilizing solar electric propulsion creates an electromagnetic environment that is potentially deterimental to the science, navigation, and radio communication hardware. Within the scope of the solar electric propulsion system technology program, three lightweight, 2.5-kW PCs were evaluated in terms of their electromagnetic characteristics. It was found that the levels of radiated and conducted interference exceeded the levels anticipated for a solar electric propulsion mission. These noise emissions, however, were the result of deficient interference design in these models, rather than a basic inability to control interference in this type of PC.

Adopting Industry Standards for Control Systems Within Advanced Life Support

NASA Technical Reports Server (NTRS)

Young, James Scott; Boulanger, Richard

2002-01-01

This paper gives a description of OPC (Object Linking and Embedding for Process Control) standards for process control and outlines the experiences at JSC with using these standards to interface with I/O hardware from three independent vendors. The I/O hardware was integrated with a commercially available SCADA/HMI software package to make up the control and monitoring system for the Environmental Systems Test Stand (ESTS). OPC standards were utilized for communicating with I/O hardware and the software was used for implementing monitoring, PC-based distributed control, and redundant data storage over an Ethernet physical layer using an embedded din-rail mounted PC.

FPGA-based distributed computing microarchitecture for complex physical dynamics investigation.

PubMed

Borgese, Gianluca; Pace, Calogero; Pantano, Pietro; Bilotta, Eleonora

2013-09-01

In this paper, we present a distributed computing system, called DCMARK, aimed at solving partial differential equations at the basis of many investigation fields, such as solid state physics, nuclear physics, and plasma physics. This distributed architecture is based on the cellular neural network paradigm, which allows us to divide the differential equation system solving into many parallel integration operations to be executed by a custom multiprocessor system. We push the number of processors to the limit of one processor for each equation. In order to test the present idea, we choose to implement DCMARK on a single FPGA, designing the single processor in order to minimize its hardware requirements and to obtain a large number of easily interconnected processors. This approach is particularly suited to study the properties of 1-, 2- and 3-D locally interconnected dynamical systems. In order to test the computing platform, we implement a 200 cells, Korteweg-de Vries (KdV) equation solver and perform a comparison between simulations conducted on a high performance PC and on our system. Since our distributed architecture takes a constant computing time to solve the equation system, independently of the number of dynamical elements (cells) of the CNN array, it allows us to reduce the elaboration time more than other similar systems in the literature. To ensure a high level of reconfigurability, we design a compact system on programmable chip managed by a softcore processor, which controls the fast data/control communication between our system and a PC Host. An intuitively graphical user interface allows us to change the calculation parameters and plot the results.

Optical processing for future computer networks

NASA Technical Reports Server (NTRS)

Husain, A.; Haugen, P. R.; Hutcheson, L. D.; Warrior, J.; Murray, N.; Beatty, M.

1986-01-01

In the development of future data management systems, such as the NASA Space Station, a major problem represents the design and implementation of a high performance communication network which is self-correcting and repairing, flexible, and evolvable. To obtain the goal of designing such a network, it will be essential to incorporate distributed adaptive network control techniques. The present paper provides an outline of the functional and communication network requirements for the Space Station data management system. Attention is given to the mathematical representation of the operations being carried out to provide the required functionality at each layer of communication protocol on the model. The possible implementation of specific communication functions in optics is also considered.

Interstellar communication. II. Application to the solar gravitational lens

NASA Astrophysics Data System (ADS)

Hippke, Michael

2018-01-01

We have shown in paper I of this series [1] that interstellar communication to nearby (pc) stars is possible at data rates of bits per second per Watt between a 1 m sized probe and a large receiving telescope (E-ELT, 39 m), when optimizing all parameters such as frequency at 300-400 nm. We now apply our framework of interstellar extinction and quantum state calculations for photon encoding to the solar gravitational lens (SGL), which enlarges the aperture (and thus the photon flux) of the receiving telescope by a factor of >109 . For the first time, we show that the use of the SGL for communication purposes is possible. This was previously unclear because the Einstein ring is placed inside the solar coronal noise, and contributing factors are difficult to determine. We calculate point-spread functions, aperture sizes, heliocentric distance, and optimum communication frequency. The best wavelength for nearby (< 100 pc) interstellar communication is limited by current technology to the UV and optical band. To suppress coronal noise, an advanced coronograph is required, alternatively an occulter could be used which would require a second spacecraft in formation flight 78 km from the receiver, and ≈ 10 m in size. Data rates scale approximately linear with the SGL telescope size and with heliocentric distance. Achievable (receiving) data rates from α Cen are of order 10 Mbits per second per Watt for a pair of meter-sized telescopes, an improvement of 107 compared to using the same receiving telescope without the SGL. A 1 m telescope in the SGL can receive data at rates comparable to a km-class "normal" telescope.

Communication and patient participation influencing patient recall of treatment discussions.

PubMed

Richard, Claude; Glaser, Emma; Lussier, Marie-Thérèse

2017-08-01

Patient recall of treatment information is a key variable towards chronic disease (CD) management. It is unclear what communication and patient participation characteristics predict recall. To assess what aspects of doctor-patient communication predict patient recall of medication information. To describe lifestyle treatment recall, in CD primary care patients. Observational study within a RCT. Community-based primary care (PC) practices. Family physicians (n=18): practicing >5 years, with a CD patient caseload. Patients (n=159): >40 years old, English speaking, computer literate, off-target hypertension, type II diabetes and/or dyslipidaemia. Patient characteristics: age, education, number of CDs. Information characteristics: length of encounter, medication status, medication class. Communication variables: socio-emotional utterances, physician dominance and communication control scores and PACE (ask, check and express) utterances, measured by RIAS. Number of medication themes, dialogue and initiative measured by MEDICODE. Recall of CD, lifestyle treatment and medication information. Frequency of lifestyle discussions varied by topic. Patients recalled 43% (alcohol), 52% (diet) to 70% (exercise) of discussions. Two and a half of six possible medication themes were broached per medication discussion. Less than one was recalled. Discussing more themes, greater dialogue and patient initiative were significant predictors of improved medication information recall. Critical treatment information is infrequently exchanged. Active patient engagement and explicit conversations about medications are associated with improved treatment information recall in off-target CD patients followed in PC. Providers cannot take for granted that long-term off-target CD patients recall information. They need to encourage patient participation to improve recall of treatment information. © 2016 The Authors. Health Expectations Published by John Wiley & Sons Ltd.

Mechanical Cell-Cell Communication in Fibrous Networks: The Importance of Network Geometry.

PubMed

Humphries, D L; Grogan, J A; Gaffney, E A

2017-03-01

Cells contracting in extracellular matrix (ECM) can transmit stress over long distances, communicating their position and orientation to cells many tens of micrometres away. Such phenomena are not observed when cells are seeded on substrates with linear elastic properties, such as polyacrylamide (PA) gel. The ability for fibrous substrates to support far reaching stress and strain fields has implications for many physiological processes, while the mechanical properties of ECM are central to several pathological processes, including tumour invasion and fibrosis. Theoretical models have investigated the properties of ECM in a variety of network geometries. However, the effects of network architecture on mechanical cell-cell communication have received little attention. This work investigates the effects of geometry on network mechanics, and thus the ability for cells to communicate mechanically through different networks. Cell-derived displacement fields are quantified for various network geometries while controlling for network topology, cross-link density and micromechanical properties. We find that the heterogeneity of response, fibre alignment, and substrate displacement fields are sensitive to network choice. Further, we show that certain geometries support mechanical communication over longer distances than others. As such, we predict that the choice of network geometry is important in fundamental modelling of cell-cell interactions in fibrous substrates, as well as in experimental settings, where mechanical signalling at the cellular scale plays an important role. This work thus informs the construction of theoretical models for substrate mechanics and experimental explorations of mechanical cell-cell communication.

Hybrid Communication Architectures for Distributed Smart Grid Applications

DOE PAGES

Zhang, Jianhua; Hasandka, Adarsh; Wei, Jin; ...

2018-04-09

Wired and wireless communications both play an important role in the blend of communications technologies necessary to enable future smart grid communications. Hybrid networks exploit independent mediums to extend network coverage and improve performance. However, whereas individual technologies have been applied in simulation networks, as far as we know there is only limited attention that has been paid to the development of a suite of hybrid communication simulation models for the communications system design. Hybrid simulation models are needed to capture the mixed communication technologies and IP address mechanisms in one simulation. To close this gap, we have developed amore » suite of hybrid communication system simulation models to validate the critical system design criteria for a distributed solar Photovoltaic (PV) communications system, including a single trip latency of 300 ms, throughput of 9.6 Kbps, and packet loss rate of 1%. In conclusion, the results show that three low-power wireless personal area network (LoWPAN)-based hybrid architectures can satisfy three performance metrics that are critical for distributed energy resource communications.« less

Hybrid Communication Architectures for Distributed Smart Grid Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Jianhua; Hasandka, Adarsh; Wei, Jin

Wired and wireless communications both play an important role in the blend of communications technologies necessary to enable future smart grid communications. Hybrid networks exploit independent mediums to extend network coverage and improve performance. However, whereas individual technologies have been applied in simulation networks, as far as we know there is only limited attention that has been paid to the development of a suite of hybrid communication simulation models for the communications system design. Hybrid simulation models are needed to capture the mixed communication technologies and IP address mechanisms in one simulation. To close this gap, we have developed amore » suite of hybrid communication system simulation models to validate the critical system design criteria for a distributed solar Photovoltaic (PV) communications system, including a single trip latency of 300 ms, throughput of 9.6 Kbps, and packet loss rate of 1%. In conclusion, the results show that three low-power wireless personal area network (LoWPAN)-based hybrid architectures can satisfy three performance metrics that are critical for distributed energy resource communications.« less

Interconnect Performance Evaluation of SGI Altix 3700 BX2, Cray X1, Cray Opteron Cluster, and Dell PowerEdge

NASA Technical Reports Server (NTRS)

Fatoohi, Rod; Saini, Subbash; Ciotti, Robert

2006-01-01

We study the performance of inter-process communication on four high-speed multiprocessor systems using a set of communication benchmarks. The goal is to identify certain limiting factors and bottlenecks with the interconnect of these systems as well as to compare these interconnects. We measured network bandwidth using different number of communicating processors and communication patterns, such as point-to-point communication, collective communication, and dense communication patterns. The four platforms are: a 512-processor SGI Altix 3700 BX2 shared-memory machine with 3.2 GB/s links; a 64-processor (single-streaming) Cray XI shared-memory machine with 32 1.6 GB/s links; a 128-processor Cray Opteron cluster using a Myrinet network; and a 1280-node Dell PowerEdge cluster with an InfiniBand network. Our, results show the impact of the network bandwidth and topology on the overall performance of each interconnect.

Flexible network wireless transceiver and flexible network telemetry transceiver

DOEpatents

Brown, Kenneth D.

2008-08-05

A transceiver for facilitating two-way wireless communication between a baseband application and other nodes in a wireless network, wherein the transceiver provides baseband communication networking and necessary configuration and control functions along with transmitter, receiver, and antenna functions to enable the wireless communication. More specifically, the transceiver provides a long-range wireless duplex communication node or channel between the baseband application, which is associated with a mobile or fixed space, air, water, or ground vehicle or other platform, and other nodes in the wireless network or grid. The transceiver broadly comprises a communication processor; a flexible telemetry transceiver including a receiver and a transmitter; a power conversion and regulation mechanism; a diplexer; and a phased array antenna system, wherein these various components and certain subcomponents thereof may be separately enclosed and distributable relative to the other components and subcomponents.

PC-Based Virtual Reality for CAD Model Viewing

ERIC Educational Resources Information Center

Seth, Abhishek; Smith, Shana S.-F.

2004-01-01

Virtual reality (VR), as an emerging visualization technology, has introduced an unprecedented communication method for collaborative design. VR refers to an immersive, interactive, multisensory, viewer-centered, 3D computer-generated environment and the combination of technologies required to build such an environment. This article introduces the…

Design of Hybrid Mobile Communication Networks for Planetary Exploration

NASA Technical Reports Server (NTRS)

Alena, Richard L.; Ossenfort, John; Lee, Charles; Walker, Edward; Stone, Thom

2004-01-01

The Mobile Exploration System Project (MEX) at NASA Ames Research Center has been conducting studies into hybrid communication networks for future planetary missions. These networks consist of space-based communication assets connected to ground-based Internets and planetary surface-based mobile wireless networks. These hybrid mobile networks have been deployed in rugged field locations in the American desert and the Canadian arctic for support of science and simulation activities on at least six occasions. This work has been conducted over the past five years resulting in evolving architectural complexity, improved component characteristics and better analysis and test methods. A rich set of data and techniques have resulted from the development and field testing of the communication network during field expeditions such as the Haughton Mars Project and NASA Mobile Agents Project.

A MATLAB based Distributed Real-time Simulation of Lander-Orbiter-Earth Communication for Lunar Missions

NASA Astrophysics Data System (ADS)

Choudhury, Diptyajit; Angeloski, Aleksandar; Ziah, Haseeb; Buchholz, Hilmar; Landsman, Andre; Gupta, Amitava; Mitra, Tiyasa

Lunar explorations often involve use of a lunar lander , a rover [1],[2] and an orbiter which rotates around the moon with a fixed radius. The orbiters are usually lunar satellites orbiting along a polar orbit to ensure visibility with respect to the rover and the Earth Station although with varying latency. Communication in such deep space missions is usually done using a specialized protocol like Proximity-1[3]. MATLAB simulation of Proximity-1 have been attempted by some contemporary researchers[4] to simulate all features like transmission control, delay etc. In this paper it is attempted to simulate, in real time, the communication between a tracking station on earth (earth station), a lunar orbiter and a lunar rover using concepts of Distributed Real-time Simulation(DRTS).The objective of the simulation is to simulate, in real-time, the time varying communication delays associated with the communicating elements with a facility to integrate specific simulation modules to study different aspects e.g. response due to a specific control command from the earth station to be executed by the rover. The hardware platform comprises four single board computers operating as stand-alone real time systems (developed by MATLAB xPC target and inter-networked using UDP-IP protocol). A time triggered DRTS approach is adopted. The earth station, the orbiter and the rover are programmed as three standalone real-time processes representing the communicating elements in the system. Communication from one communicating element to another constitutes an event which passes a state message from one element to another, augmenting the state of the latter. These events are handled by an event scheduler which is the fourth real-time process. The event scheduler simulates the delay in space communication taking into consideration the distance between the communicating elements. A unique time synchronization algorithm is developed which takes into account the large latencies in space communication. The DRTS setup thus developed serves as an important and inexpensive test bench for trying out remote controlled applications on the rover, for example, from an earth station. The simulation is modular and the system is composable. Each of the processes can be aug-mented with relevant simulation modules that handle the events to simulate specific function-alities. With stringent energy saving requirements on most rovers, such a simulation set up, for example, can be used to design optimal rover movement control strategies from the orbiter in conjunction with autonomous systems on the rover itself. References 1. Lunar and Planetary Department, Moscow University, Lunokhod 1, "http://selena.sai.msu.ru/Home/Spa 2. NASA History Office, Guidelines for Advanced Manned Space Vehicle Program, "http://history.nasa.gov 35ann/AMSVPguidelines/top.htm" 3. Consultative Committee For Space Data Systems, "Proximity-1 Space Link Protocol" CCSDS 211.0-B-1 Blue Book. October 2002. 4. Segui, J. and Jennings, E., "Delay Tolerant Networking-Bundle Protocol Simulation", in Proceedings of the 2nd IEEE International Conference on Space Mission Challenges for Infor-mation Technology, 2006.

Fiber-Optic Network Architectures for Onboard Avionics Applications Investigated

NASA Technical Reports Server (NTRS)

Nguyen, Hung D.; Ngo, Duc H.

2003-01-01

This project is part of a study within the Advanced Air Transportation Technologies program undertaken at the NASA Glenn Research Center. The main focus of the program is the improvement of air transportation, with particular emphasis on air transportation safety. Current and future advances in digital data communications between an aircraft and the outside world will require high-bandwidth onboard communication networks. Radiofrequency (RF) systems, with their interconnection network based on coaxial cables and waveguides, increase the complexity of communication systems onboard modern civil and military aircraft with respect to weight, power consumption, and safety. In addition, safety and reliability concerns from electromagnetic interference between the RF components embedded in these communication systems exist. A simple, reliable, and lightweight network that is free from the effects of electromagnetic interference and capable of supporting the broadband communications needs of future onboard digital avionics systems cannot be easily implemented using existing coaxial cable-based systems. Fiber-optical communication systems can meet all these challenges of modern avionics applications in an efficient, cost-effective manner. The objective of this project is to present a number of optical network architectures for onboard RF signal distribution. Because of the emergence of a number of digital avionics devices requiring high-bandwidth connectivity, fiber-optic RF networks onboard modern aircraft will play a vital role in ensuring a low-noise, highly reliable RF communication system. Two approaches are being used for network architectures for aircraft onboard fiber-optic distribution systems: a hybrid RF-optical network and an all-optical wavelength division multiplexing (WDM) network.

7.3 Communications and Navigation

NASA Technical Reports Server (NTRS)

Manning, Rob

2005-01-01

This presentation gives an overview of the networks NASA currently uses to support space communications and navigation, and the requirements for supporting future deep space missions, including manned lunar and Mars missions. The presentation addresses the Space Network, Deep Space Network, and Ground Network, why new support systems are needed, and the potential for catastrophic failure of aging antennas. Space communications and navigation are considered during Aerocapture, Entry, Descent and Landing (AEDL) only in order to precisely position, track and interact with the spacecraft at its destination (moon, Mars and Earth return) arrival. The presentation recommends a combined optical/radio frequency strategy for deep space communications.

System architecture for an advanced Canadian communications satellite demonstration mission

NASA Astrophysics Data System (ADS)

Takats, P.; Irani, S.

1992-03-01

An advanced communications satellite system that provides single hop interconnectivity and interworking for both a personal communications network and an advanced private business network in the Ka and Ku bands respectively, is presented. An overall network perspective is discussed that studies the interface of such an advanced satellite communication system to the terrestrial network in the context of the Open Systems Interconnection model. It is shown that this proposed satellite system can dynamically establish links and efficiently allocate the satellite resource amongst the user terminal population for a mix of data and voice traffic.

Trend on High-speed Power Line Communication Technology

NASA Astrophysics Data System (ADS)

Ogawa, Osamu

High-speed power line communication (PLC) is useful technology to easily build the communication networks, because construction of new infrastructure is not necessary. In Europe and America, PLC has been used for broadband networks since the beginning of 21th century. In Japan, high-speed PLC was deregulated only indoor usage in 2006. Afterward it has been widely used for home area network, LAN in hotels and school buildings and so on. And recently, PLC is greatly concerned as communication technology for smart grid network. In this paper, the author surveys the high-speed PLC technology and its current status.

Evaluating organizational change in health care: the patient-centered hospital model.

PubMed

Fiorio, Carlo V; Gorli, Mara; Verzillo, Stefano

2018-02-08

An increasing number of hospitals react to recent demographic, epidemiological and managerial challenges moving from a traditional organizational model to a Patient-Centered (PC) hospital model. Although the theoretical managerial literature on the PC hospital model is vast, quantitative evaluations of the performance of hospitals that moved from the traditional to the PC organizational structure is scarce. However, quantitative analysis of effects of managerial changes is important and can provide additional argument in support of innovation. We take advantage of a quasi-experimental setting and of a unique administrative data set on the population of hospital discharge charts (HDCs) over a period of 9 years of Lombardy, the richest and one of the most populated region of Italy. During this period three important hospitals switched to the PC model in 2010, whereas all the others remained with the functional organizational model. This allowed us to develop a difference-in-difference analysis of some selected measures of efficiency and effectiveness for PC hospitals focusing on the "between-variability" of the 25 major diagnostic categories (MDCs) in each hospital and estimating a difference-in-difference model. We contribute to the literature that addresses the evaluation of healthcare and hospital change by providing a quantitative estimation of efficiency and effectiveness changes following to the implementation of the PC hospital model. Results show that both efficiency and effectiveness have significantly increased in the average MDC of PC hospitals, thus confirming the need for policy makers to invest in new organizational models close to the principles of PC hospital structures. Although an organizational change towards the PC model can be a costly process, implying a rebalancing of responsibilities and power among hospital personnel (e.g. medical and nursing staff), our results suggest that changing towards a PC model can be worthwhile in terms of both efficacy and efficiency. This evidence can be used to inform and sustain hospital managers and policy makers in their hospital design efforts and to communicate the innovation advantages within the hospital organizations, among the personnel and in the public debate.

The impact of socio-technical communication styles on the diversity and innovation potential of global science collaboratories

DOE PAGES

Ozmen, Ozgur; Yilmaz, Levent; Smith, Jeffrey

2016-02-09

Emerging cyber-infrastructure tools are enabling scientists to transparently co-develop, share, and communicate about real-time diverse forms of knowledge artifacts. In these environments, communication preferences of scientists are posited as an important factor affecting innovation capacity and robustness of social and knowledge network structures. Scientific knowledge creation in such communities is called global participatory science (GPS). Recently, using agent-based modeling and collective action theory as a basis, a complex adaptive social communication network model (CollectiveInnoSim) is implemented. This work leverages CollectiveInnoSim implementing communication preferences of scientists. Social network metrics and knowledge production patterns are used as proxy metrics to infer innovationmore » potential of emergent knowledge and collaboration networks. The objective is to present the underlying communication dynamics of GPS in a form of computational model and delineate the impacts of various communication preferences of scientists on innovation potential of the collaboration network. Ultimately, the insight gained can help policy-makers to design GPS environments and promote innovation.« less

The impact of socio-technical communication styles on the diversity and innovation potential of global science collaboratories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ozmen, Ozgur; Yilmaz, Levent; Smith, Jeffrey

Emerging cyber-infrastructure tools are enabling scientists to transparently co-develop, share, and communicate about real-time diverse forms of knowledge artifacts. In these environments, communication preferences of scientists are posited as an important factor affecting innovation capacity and robustness of social and knowledge network structures. Scientific knowledge creation in such communities is called global participatory science (GPS). Recently, using agent-based modeling and collective action theory as a basis, a complex adaptive social communication network model (CollectiveInnoSim) is implemented. This work leverages CollectiveInnoSim implementing communication preferences of scientists. Social network metrics and knowledge production patterns are used as proxy metrics to infer innovationmore » potential of emergent knowledge and collaboration networks. The objective is to present the underlying communication dynamics of GPS in a form of computational model and delineate the impacts of various communication preferences of scientists on innovation potential of the collaboration network. Ultimately, the insight gained can help policy-makers to design GPS environments and promote innovation.« less

The integrated proactive surveillance system for prostate cancer.

PubMed

Wang, Haibin; Yatawara, Mahendra; Huang, Shao-Chi; Dudley, Kevin; Szekely, Christine; Holden, Stuart; Piantadosi, Steven

2012-01-01

In this paper, we present the design and implementation of the integrated proactive surveillance system for prostate cancer (PASS-PC). The integrated PASS-PC is a multi-institutional web-based system aimed at collecting a variety of data on prostate cancer patients in a standardized and efficient way. The integrated PASS-PC was commissioned by the Prostate Cancer Foundation (PCF) and built through the joint of efforts by a group of experts in medical oncology, genetics, pathology, nutrition, and cancer research informatics. Their main goal is facilitating the efficient and uniform collection of critical demographic, lifestyle, nutritional, dietary and clinical information to be used in developing new strategies in diagnosing, preventing and treating prostate cancer.The integrated PASS-PC is designed based on common industry standards - a three tiered architecture and a Service- Oriented Architecture (SOA). It utilizes open source software and programming languages such as HTML, PHP, CSS, JQuery, Drupal and MySQL. We also use a commercial database management system - Oracle 11g. The integrated PASS-PC project uses a "confederation model" that encourages participation of any interested center, irrespective of its size or location. The integrated PASS-PC utilizes a standardized approach to data collection and reporting, and uses extensive validation procedures to prevent entering erroneous data. The integrated PASS-PC controlled vocabulary is harmonized with the National Cancer Institute (NCI) Thesaurus. Currently, two cancer centers in the USA are participating in the integrated PASS-PC project.THE FINAL SYSTEM HAS THREE MAIN COMPONENTS: 1. National Prostate Surveillance Network (NPSN) website; 2. NPSN myConnect portal; 3. Proactive Surveillance System for Prostate Cancer (PASS-PC). PASS-PC is a cancer Biomedical Informatics Grid (caBIG) compatible product. The integrated PASS-PC provides a foundation for collaborative prostate cancer research. It has been built to meet the short term goal of gathering prostate cancer related data, but also with the prerequisites in place for future evolution into a cancer research informatics platform. In the future this will be vital for successful prostate cancer studies, care and treatment.

The Integrated Proactive Surveillance System for Prostate Cancer

PubMed Central

Wang, Haibin; Yatawara, Mahendra; Huang, Shao-Chi; Dudley, Kevin; Szekely, Christine; Holden, Stuart; Piantadosi, Steven

2012-01-01

In this paper, we present the design and implementation of the integrated proactive surveillance system for prostate cancer (PASS-PC). The integrated PASS-PC is a multi-institutional web-based system aimed at collecting a variety of data on prostate cancer patients in a standardized and efficient way. The integrated PASS-PC was commissioned by the Prostate Cancer Foundation (PCF) and built through the joint of efforts by a group of experts in medical oncology, genetics, pathology, nutrition, and cancer research informatics. Their main goal is facilitating the efficient and uniform collection of critical demographic, lifestyle, nutritional, dietary and clinical information to be used in developing new strategies in diagnosing, preventing and treating prostate cancer. The integrated PASS-PC is designed based on common industry standards – a three tiered architecture and a Service- Oriented Architecture (SOA). It utilizes open source software and programming languages such as HTML, PHP, CSS, JQuery, Drupal and MySQL. We also use a commercial database management system – Oracle 11g. The integrated PASS-PC project uses a “confederation model” that encourages participation of any interested center, irrespective of its size or location. The integrated PASS-PC utilizes a standardized approach to data collection and reporting, and uses extensive validation procedures to prevent entering erroneous data. The integrated PASS-PC controlled vocabulary is harmonized with the National Cancer Institute (NCI) Thesaurus. Currently, two cancer centers in the USA are participating in the integrated PASS-PC project. The final system has three main components: 1. National Prostate Surveillance Network (NPSN) website; 2. NPSN myConnect portal; 3. Proactive Surveillance System for Prostate Cancer (PASS-PC). PASS-PC is a cancer Biomedical Informatics Grid (caBIG) compatible product. The integrated PASS-PC provides a foundation for collaborative prostate cancer research. It has been built to meet the short term goal of gathering prostate cancer related data, but also with the prerequisites in place for future evolution into a cancer research informatics platform. In the future this will be vital for successful prostate cancer studies, care and treatment. PMID:22505956

Creating wi-fi bluetooth mesh network for crisis management applications

NASA Astrophysics Data System (ADS)

Al-Tekreeti, Safa; Adams, Christopher; Al-Jawad, Naseer

2010-04-01

This paper proposes a wireless mesh network implementation consisting of both Wi-Fi Ad-Hoc networks as well as Bluetooth Piconet/Scatternet networks, organised in an energy and throughput efficient structure. This type of networks can be easily constructed for Crises management applications, for example in an Earthquake disaster. The motivation of this research is to form mesh network from the mass availability of WiFi and Bluetooth enabled electronic devices such as mobile phones and PC's that are normally present in most regions were major crises occurs. The target of this study is to achieve an effective solution that will enable Wi-Fi and/or Bluetooth nodes to seamlessly configure themselves to act as a bridge between their own network and that of the other network to achieve continuous routing for our proposed mesh networks.

Power-law behavior in complex organizational communication networks during crisis

NASA Astrophysics Data System (ADS)

Uddin, Shahadat; Murshed, Shahriar Tanvir Hasan; Hossain, Liaquat

2011-08-01

Communication networks can be described as patterns of contacts which are created due to the flow of messages and information shared among participating actors. Contemporary organizations are now commonly viewed as dynamic systems of adaptation and evolution containing several parts, which interact with one another both in internal and in external environment. Although there is limited consensus among researchers on the precise definition of organizational crisis, there is evidence of shared meaning: crisis produces individual crisis, crisis can be associated with positive or negative conditions, crises can be situations having been precipitated quickly or suddenly or situations that have developed over time and are predictable etc. In this research, we study the power-law behavior of an organizational email communication network during crisis from complexity perspective. Power law simply describes that, the probability that a randomly selected node has k links (i.e. degree k) follows P(k)∼k, where γ is the degree exponent. We used social network analysis tools and techniques to analyze the email communication dataset. We tested two propositions: (1) as organization goes through crisis, a few actors, who are prominent or more active, will become central, and (2) the daily communication network as well as the actors in the communication network exhibit power-law behavior. Our preliminary results support these two propositions. The outcome of this study may provide significant advancement in exploring organizational communication network behavior during crisis.

Implementing an Automated Antenna Measurement System

NASA Technical Reports Server (NTRS)

Valerio, Matthew D.; Romanofsky, Robert R.; VanKeuls, Fred W.

2003-01-01

We developed an automated measurement system using a PC running a LabView application, a Velmex BiSlide X-Y positioner, and a HP85l0C network analyzer. The system provides high positioning accuracy and requires no user supervision. After the user inputs the necessary parameters into the LabView application, LabView controls the motor positioning and performs the data acquisition. Current parameters and measured data are shown on the PC display in two 3-D graphs and updated after every data point is collected. The final output is a formatted data file for later processing.

Ad Hoc Access Gateway Selection Algorithm

NASA Astrophysics Data System (ADS)

Jie, Liu

With the continuous development of mobile communication technology, Ad Hoc access network has become a hot research, Ad Hoc access network nodes can be used to expand capacity of multi-hop communication range of mobile communication system, even business adjacent to the community, improve edge data rates. For mobile nodes in Ad Hoc network to internet, internet communications in the peer nodes must be achieved through the gateway. Therefore, the key Ad Hoc Access Networks will focus on the discovery gateway, as well as gateway selection in the case of multi-gateway and handover problems between different gateways. This paper considers the mobile node and the gateway, based on the average number of hops from an average access time and the stability of routes, improved gateway selection algorithm were proposed. An improved gateway selection algorithm, which mainly considers the algorithm can improve the access time of Ad Hoc nodes and the continuity of communication between the gateways, were proposed. This can improve the quality of communication across the network.

Communication networks of men facing a diagnosis of prostate cancer.

PubMed

Brown, Dot; Oetzel, John; Henderson, Alison

2016-11-01

This study seeks to identify the factors that shape the communication networks of men who face a potential diagnosis of prostate cancer, and how these factors relate to their disclosure about their changing health status. Men facing a potential diagnosis of prostate cancer are in a challenging situation; the support benefits of disclosing their changing health status to others in their communication networks is set against a backdrop of the potential stigma and uncertainty of the diagnosis. All men on a prostate biopsy waiting list were eligible for inclusion in an exploratory and interpretive study. Semi-structured interviews with 40 men explored their network structures and disclosure of health information. Thematic analysis highlighted the factors which contributed to their network structures and their disclosure about their health status. Four network factors shaped men's perspectives about disclosing their health status: (1) tie strength, comprising both strong and weak ties; (2) knowledgeable others, with a focus on medical professionals in the family; (3) homophily, which included other individuals with a similar medical condition; and (4) geographical proximity, with a preference for face-to-face communication. Communication networks influence men's disclosure of their health status and in particular weak ties with medical knowledge have an important role. Men who use the potential for support in their networks may experience improved psychosocial outcomes. Using these four network factors-tie strength, knowledgeable others, homophily or geographical proximity-to forecast men's willingness to disclose helps identify men who lack potential support and so are at risk of poor psychosocial health. Those with few strong ties or knowledgeable others in their networks may be in the at-risk cohort. The support provided in communication networks complements formal medical care from nurses and other health professionals, and encouraging patients to use their communication networks improves the psychosocial health of the men themselves, their partners and their families. © 2016 John Wiley & Sons Ltd.

The Deep Space Network. [tracking and communication functions and facilities

NASA Technical Reports Server (NTRS)

1974-01-01

The objectives, functions, and organization of the Deep Space Network are summarized. The Deep Space Instrumentation Facility, the Ground Communications Facility, and the Network Control System are described.

Compliance and Functional Testing of IEEE 1451.1 for NCAP-to-NCAP Communications in a Sensor Network

NASA Technical Reports Server (NTRS)

Figueroa, Jorge; Gurkan, Deniz; Yuan, X.; Benhaddou, D.; Liu, H.; Singla, A.; Franzl, R.; Ma, H.; Bhatt, S.; Morris, J.;

Statistically validated mobile communication networks: the evolution of motifs in European and Chinese data

NASA Astrophysics Data System (ADS)

Li, Ming-Xia; Palchykov, Vasyl; Jiang, Zhi-Qiang; Kaski, Kimmo; Kertész, János; Miccichè, Salvatore; Tumminello, Michele; Zhou, Wei-Xing; Mantegna, Rosario N.

2014-08-01

Big data open up unprecedented opportunities for investigating complex systems, including society. In particular, communication data serve as major sources for computational social sciences, but they have to be cleaned and filtered as they may contain spurious information due to recording errors as well as interactions, like commercial and marketing activities, not directly related to the social network. The network constructed from communication data can only be considered as a proxy for the network of social relationships. Here we apply a systematic method, based on multiple-hypothesis testing, to statistically validate the links and then construct the corresponding Bonferroni network, generalized to the directed case. We study two large datasets of mobile phone records, one from Europe and the other from China. For both datasets we compare the raw data networks with the corresponding Bonferroni networks and point out significant differences in the structures and in the basic network measures. We show evidence that the Bonferroni network provides a better proxy for the network of social interactions than the original one. Using the filtered networks, we investigated the statistics and temporal evolution of small directed 3-motifs and concluded that closed communication triads have a formation time scale, which is quite fast and typically intraday. We also find that open communication triads preferentially evolve into other open triads with a higher fraction of reciprocated calls. These stylized facts were observed for both datasets.

Digital Networked Information Society and Public Health: Problems and Promises of Networked Health Communication of Lay Publics.

PubMed

Kim, Jeong-Nam

2018-01-01

This special issue of Health Communication compiles 10 articles to laud the promise and yet confront the problems in the digital networked information society related to public health. We present this anthology of symphony and cacophony of lay individuals' communicative actions in a digital networked information society. The collection of problems and promise of the new digital world may be a cornerstone joining two worlds-pre- and postdigital network society-and we hope this special issue will help better shape our future states of public health.

Development of a space-systems network testbed

NASA Technical Reports Server (NTRS)

Lala, Jaynarayan; Alger, Linda; Adams, Stuart; Burkhardt, Laura; Nagle, Gail; Murray, Nicholas

1988-01-01

This paper describes a communications network testbed which has been designed to allow the development of architectures and algorithms that meet the functional requirements of future NASA communication systems. The central hardware components of the Network Testbed are programmable circuit switching communication nodes which can be adapted by software or firmware changes to customize the testbed to particular architectures and algorithms. Fault detection, isolation, and reconfiguration has been implemented in the Network with a hybrid approach which utilizes features of both centralized and distributed techniques to provide efficient handling of faults within the Network.

A game-theoretic approach to optimize ad hoc networks inspired by small-world network topology

NASA Astrophysics Data System (ADS)

Tan, Mian; Yang, Tinghong; Chen, Xing; Yang, Gang; Zhu, Guoqing; Holme, Petter; Zhao, Jing

2018-03-01

Nodes in ad hoc networks are connected in a self-organized manner. Limited communication radius makes information transmit in multi-hop mode, and each forwarding needs to consume the energy of nodes. Insufficient communication radius or exhaustion of energy may cause the absence of some relay nodes and links, further breaking network connectivity. On the other hand, nodes in the network may refuse to cooperate due to objective faulty or personal selfish, hindering regular communication in the network. This paper proposes a model called Repeated Game in Small World Networks (RGSWN). In this model, we first construct ad hoc networks with small-world feature by forming "communication shortcuts" between multiple-radio nodes. Small characteristic path length reduces average forwarding times in networks; meanwhile high clustering coefficient enhances network robustness. Such networks still maintain relative low global power consumption, which is beneficial to extend the network survival time. Then we use MTTFT strategy (Mend-Tolerance Tit-for-Tat) for repeated game as a rule for the interactions between neighbors in the small-world networks. Compared with other five strategies of repeated game, this strategy not only punishes the nodes' selfishness more reasonably, but also has the best tolerance to the network failure. This work is insightful for designing an efficient and robust ad hoc network.

Teaching Students How to Integrate and Assess Social Networking Tools in Marketing Communications

ERIC Educational Resources Information Center

Schlee, Regina Pefanis; Harich, Katrin R.

2013-01-01

This research is based on two studies that focus on teaching students how to integrate and assess social networking tools in marketing communications. Study 1 examines how students in marketing classes utilize social networking tools and explores their attitudes regarding the use of such tools for marketing communications. Study 2 focuses on an…

Multireceiver Acoustic Communications in Time-Varying Environments

DTIC Science & Technology

2014-06-01

Canberra, ACT, 2012, pp. 1–7. [7] W. Chen and F. Yanjun, “Physical layer design consideration for underwater acoustic sensor networks ,”3rd IEEE Int...analysis of underwater acoustic MIMO communications,”OCEANS, Sydney, NSW, 2010, pp. 1–8. [9] Wines lab (2013). Wireless networks and embedded... NETWORKS ......................................................................3 B. CHALLENGES OF UNDERWATER ACOUSTIC COMMUNICATIONS

The Deep Space Network: A Radio Communications Instrument for Deep Space Exploration

NASA Technical Reports Server (NTRS)

Renzetti, N. A.; Stelzried, C. T.; Noreen, G. K.; Slobin, S. D.; Petty, S. M.; Trowbridge, D. L.; Donnelly, H.; Kinman, P. W.; Armstrong, J. W.; Burow, N. A.

1983-01-01

The primary purpose of the Deep Space Network (DSN) is to serve as a communications instrument for deep space exploration, providing communications between the spacecraft and the ground facilities. The uplink communications channel provides instructions or commands to the spacecraft. The downlink communications channel provides command verification and spacecraft engineering and science instrument payload data.

Enhanced Communication Network Solution for Positive Train Control Implementation

NASA Technical Reports Server (NTRS)

Fatehi, M. T.; Simon, J.; Chang, W.; Chow, E. T.; Burleigh, S. C.

2011-01-01

The commuter and freight railroad industry is required to implement Positive Train Control (PTC) by 2015 (2012 for Metrolink), a challenging network communications problem. This paper will discuss present technologies developed by the National Aeronautics and Space Administration (NASA) to overcome comparable communication challenges encountered in deep space mission operations. PTC will be based on a new cellular wireless packet Internet Protocol (IP) network. However, ensuring reliability in such a network is difficult due to the "dead zones" and transient disruptions we commonly experience when we lose calls in commercial cellular networks. These disruptions make it difficult to meet PTC s stringent reliability (99.999%) and safety requirements, deployment deadlines, and budget. This paper proposes innovative solutions based on space-proven technologies that would help meet these challenges: (1) Delay Tolerant Networking (DTN) technology, designed for use in resource-constrained, embedded systems and currently in use on the International Space Station, enables reliable communication over networks in which timely data acknowledgments might not be possible due to transient link outages. (2) Policy-Based Management (PBM) provides dynamic management capabilities, allowing vital data to be exchanged selectively (with priority) by utilizing alternative communication resources. The resulting network may help railroads implement PTC faster, cheaper, and more reliably.

78 FR 14490 - Petition for Reconsideration of Action in a Rulemaking Proceeding

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-06

... Project, Don Schellhardt, Esq., on behalf of LET CITIES IN!!, Michelle Eyre, on behalf of REC Networks, and Donald E. Martin P.C., on behalf of LifeTalk Radio, Inc. DATES: Oppositions to the Petitions must...

Transmission of live laparoscopic surgery over the Internet2.

PubMed

Damore, L J; Johnson, J A; Dixon, R S; Iverson, M A; Ellison, E C; Melvin, W S

1999-11-01

Video broadcasting of surgical procedures is an important tool for education, training, and consultation. Current video conferencing systems are expensive and time-consuming and require preplanning. Real-time Internet video is known for its poor quality and relies on the equipment and the speed of the connection. The Internet2, a new high-speed (up to 2,048 Mbps), large bandwidth data network presently connects more than 100 universities and corporations. We have successfully used the Internet2 to broadcast the first real-time, high-quality audio/video program from a live laparoscopic operation to distant points. Video output of the laparoscopic camera and audio from a wireless microphone were broadcast to distant sites using a proprietary, PC-based implementation of H.320 video conferencing over a TCP/IP network connected to the Internet2. The receiving sites participated in two-way, real-time video and audio communications and graded the quality of the signal they received. On August 25, 1998, a laparoscopic Nissen fundoplication was transmitted to Internet2 stations in Colorado, Pennsylvania, and to an Internet station in New York. On September 28 and 29, 1998, we broadcast laparoscopic operations throughout both days to the Internet2 Fall Conference in San Francisco, California. Most recently, on February 24, 1999, we transmitted a laparoscopic Heller myotomy to the Abilene Network Launch Event in Washington, DC. The Internet2 is currently able to provide the bandwidth needed for a turn-key video conferencing system with high-resolution, real-time transmission. The system could be used for a variety of teaching and educational programs for experienced surgeons, residents, and medical students.

REDEX - The ranging equipment diagnostic expert system

NASA Technical Reports Server (NTRS)

Luczak, Edward C.; Gopalakrishnan, K.; Zillig, David J.

1989-01-01

REDEX, an advanced prototype expert system that diagnoses hardware failures in the Ranging Equipment (RE) at NASA's Ground Network tracking stations is described. REDEX will help the RE technician identify faulty circuit cards or modules that must be replaced, and thereby reduce troubleshooting time. It features a highly graphical user interface that uses color block diagrams and layout diagrams to illustrate the location of a fault. A semantic network knowledge representation technique was used to model the design structure of the RE. A catalog of generic troubleshooting rules was compiled to represent heuristics that are applied in diagnosing electronic equipment. Specific troubleshooting rules were identified to represent additional diagnostic knowledge that is unique to the RE. Over 50 generic and 250 specific troubleshooting rules have been derived. REDEX is implemented in Prolog on an IBM PC AT-compatible workstation. Block diagram graphics displays are color-coded to identify signals that have been monitored or inferred to have nominal values, signals that are out of tolerance, and circuit cards and functions that are diagnosed as faulty. A hypertext-like scheme is used to allow the user to easily navigate through the space of diagrams and tables. Over 50 graphic and tabular displays have been implemented. REDEX is currently being evaluated in a stand-alone mode using simulated RE fault scenarios. It will soon be interfaced to the RE and tested in an online environment. When completed and fielded, REDEX will be a concrete example of the application of expert systems technology to the problem of improving performance and reducing the lifecycle costs of operating NASA's communications networks in the 1990s.

REDEX: The ranging equipment diagnostic expert system

NASA Technical Reports Server (NTRS)

Luczak, Edward C.; Gopalakrishnan, K.; Zillig, David J.

1989-01-01

REDEX, an advanced prototype expert system that diagnoses hardware failures in the Ranging Equipment (RE) at NASA's Ground Network tracking stations is described. REDEX will help the RE technician identify faulty circuit cards or modules that must be replaced, and thereby reduce troubleshooting time. It features a highly graphical user interface that uses color block diagrams and layout diagrams to illustrate the location of a fault. A semantic network knowledge representation technique was used to model the design structure of the RE. A catalog of generic troubleshooting rules was compiled to represent heuristics that are applied in diagnosing electronic equipment. Specific troubleshooting rules were identified to represent additional diagnostic knowledge that is unique to the RE. Over 50 generic and 250 specific troubleshooting rules have been derived. REDEX is implemented in Prolog on an IBM PC AT-compatible workstation. Block diagram graphics displays are color-coded to identify signals that have been monitored or inferred to have nominal values, signals that are out of tolerance, and circuit cards and functions that are diagnosed as faulty. A hypertext-like scheme is used to allow the user to easily navigate through the space of diagrams and tables. Over 50 graphic and tabular displays have been implemented. REDEX is currently being evaluated in a stand-alone mode using simulated RE fault scenarios. It will soon be interfaced to the RE and tested in an online environment. When completed and fielded, REDEX will be a concrete example of the application of expert systems technology to the problem of improving performance and reducing the lifecycle costs of operating NASA's communications networks in the 1990's.

Wireless sensor network

NASA Astrophysics Data System (ADS)

Perotti, Jose M.; Lucena, Angel R.; Mullenix, Pamela A.; Mata, Carlos T.

2006-05-01

Current and future requirements of aerospace sensors and transducers demand the design and development of a new family of sensing devices, with emphasis on reduced weight, power consumption, and physical size. This new generation of sensors and transducers will possess a certain degree of intelligence in order to provide the end user with critical data in a more efficient manner. Communication between networks of traditional or next-generation sensors can be accomplished by a Wireless Sensor Network (WSN) developed by NASA's Instrumentation Branch and ASRC Aerospace Corporation at Kennedy Space Center (KSC), consisting of at least one central station and several remote stations and their associated software. The central station is application-dependent and can be implemented on different computer hardware, including industrial, handheld, or PC-104 single-board computers, on a variety of operating systems: embedded Windows, Linux, VxWorks, etc. The central stations and remote stations share a similar radio frequency (RF) core module hardware that is modular in design. The main components of the remote stations are an RF core module, a sensor interface module, batteries, and a power management module. These modules are stackable, and a common bus provides the flexibility to stack other modules for additional memory, increased processing, etc. WSN can automatically reconfigure to an alternate frequency if interference is encountered during operation. In addition, the base station will autonomously search for a remote station that was perceived to be lost, using relay stations and alternate frequencies. Several wireless remote-station types were developed and tested in the laboratory to support different sensing technologies, such as resistive temperature devices, silicon diodes, strain gauges, pressure transducers, and hydrogen leak detectors.

REDEX - The ranging equipment diagnostic expert system

NASA Astrophysics Data System (ADS)

Luczak, Edward C.; Gopalakrishnan, K.; Zillig, David J.

REDEX, an advanced prototype expert system that diagnoses hardware failures in the Ranging Equipment (RE) at NASA's Ground Network tracking stations is described. REDEX will help the RE technician identify faulty circuit cards or modules that must be replaced, and thereby reduce troubleshooting time. It features a highly graphical user interface that uses color block diagrams and layout diagrams to illustrate the location of a fault. A semantic network knowledge representation technique was used to model the design structure of the RE. A catalog of generic troubleshooting rules was compiled to represent heuristics that are applied in diagnosing electronic equipment. Specific troubleshooting rules were identified to represent additional diagnostic knowledge that is unique to the RE. Over 50 generic and 250 specific troubleshooting rules have been derived. REDEX is implemented in Prolog on an IBM PC AT-compatible workstation. Block diagram graphics displays are color-coded to identify signals that have been monitored or inferred to have nominal values, signals that are out of tolerance, and circuit cards and functions that are diagnosed as faulty. A hypertext-like scheme is used to allow the user to easily navigate through the space of diagrams and tables. Over 50 graphic and tabular displays have been implemented. REDEX is currently being evaluated in a stand-alone mode using simulated RE fault scenarios. It will soon be interfaced to the RE and tested in an online environment. When completed and fielded, REDEX will be a concrete example of the application of expert systems technology to the problem of improving performance and reducing the lifecycle costs of operating NASA's communications networks in the 1990s.

REDEX: The ranging equipment diagnostic expert system

NASA Astrophysics Data System (ADS)

Luczak, Edward C.; Gopalakrishnan, K.; Zillig, David J.

1989-04-01

REDEX, an advanced prototype expert system that diagnoses hardware failures in the Ranging Equipment (RE) at NASA's Ground Network tracking stations is described. REDEX will help the RE technician identify faulty circuit cards or modules that must be replaced, and thereby reduce troubleshooting time. It features a highly graphical user interface that uses color block diagrams and layout diagrams to illustrate the location of a fault. A semantic network knowledge representation technique was used to model the design structure of the RE. A catalog of generic troubleshooting rules was compiled to represent heuristics that are applied in diagnosing electronic equipment. Specific troubleshooting rules were identified to represent additional diagnostic knowledge that is unique to the RE. Over 50 generic and 250 specific troubleshooting rules have been derived. REDEX is implemented in Prolog on an IBM PC AT-compatible workstation. Block diagram graphics displays are color-coded to identify signals that have been monitored or inferred to have nominal values, signals that are out of tolerance, and circuit cards and functions that are diagnosed as faulty. A hypertext-like scheme is used to allow the user to easily navigate through the space of diagrams and tables. Over 50 graphic and tabular displays have been implemented. REDEX is currently being evaluated in a stand-alone mode using simulated RE fault scenarios. It will soon be interfaced to the RE and tested in an online environment. When completed and fielded, REDEX will be a concrete example of the application of expert systems technology to the problem of improving performance and reducing the lifecycle costs of operating NASA's communications networks in the 1990's.

Optogenetic Modulation and Multi-Electrode Analysis of Cerebellar Networks In Vivo

PubMed Central

Kruse, Wolfgang; Krause, Martin; Aarse, Janna; Mark, Melanie D.; Manahan-Vaughan, Denise; Herlitze, Stefan

2014-01-01

The firing patterns of cerebellar Purkinje cells (PCs), as the sole output of the cerebellar cortex, determine and tune motor behavior. PC firing is modulated by various inputs from different brain regions and by cell-types including granule cells (GCs), climbing fibers and inhibitory interneurons. To understand how signal integration in PCs occurs and how subtle changes in the modulation of PC firing lead to adjustment of motor behaviors, it is important to precisely record PC firing in vivo and to control modulatory pathways in a spatio-temporal manner. Combining optogenetic and multi-electrode approaches, we established a new method to integrate light-guides into a multi-electrode system. With this method we are able to variably position the light-guide in defined regions relative to the recording electrode with micrometer precision. We show that PC firing can be precisely monitored and modulated by light-activation of channelrhodopsin-2 (ChR2) expressed in PCs, GCs and interneurons. Thus, this method is ideally suited to investigate the spatio/temporal modulation of PCs in anesthetized and in behaving mice. PMID:25144735

Privacy Issues of a National Research and Education Network.

ERIC Educational Resources Information Center

Katz, James E.; Graveman, Richard F.

1991-01-01

Discussion of the right to privacy of communications focuses on privacy expectations within a National Research and Education Network (NREN). Highlights include privacy needs in scientific and education communications; academic and research networks; network security and privacy concerns; protection strategies; and consequences of privacy…

Artificial Intelligence in a German Adventure Game: Spion in PROLOG.

ERIC Educational Resources Information Center

Molla, Steven R.; And Others

1988-01-01

Spion, an adventure game for intermediate and advanced college German students, requires players to communicate with a fictitious agent in complete, correct German sentences. The spy game was written in PROLOG, runs on an IBM-PC, and is available at no cost for noncommercial purposes. (Author/CB)

Using ZWDOS to Communicate in Chinese on PC.

ERIC Educational Resources Information Center

Xie, Tianwei

1995-01-01

Describes the availability, installation, and use of the ZhonWen Disk Operating System (ZWDOS) to display, print, and transmit Chinese characters on conventional International Business Machines (IBM) personal computers and IBM-compatible machines. Also discussed is the use of ZWDOS to compose electronic mail messages, read newsgroups, and access…

You Ain't Seen Nothin' Yet

ERIC Educational Resources Information Center

Strawn, George

2006-01-01

Information technology has been changing the academy for the past fifty years, but those changes are small compared with what can be expected in the next fifty years. Three relatively recent IT "subrevolutions" have had an increasing impact on research, scholarly communication, and education. These are namely: (1) "PC subrevolution" that began in…

77 FR 42491 - Announcement of the Board of Trustees for the National Environmental Education Foundation

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-19

... Channel, Chief Operating Officer of Discovery Channel, Executive Vice President of Science Channel and Chief Operating Officer of Science Channel at Discovery Communications Holding, LLC since June 2010. She..., P.C. Phillipe Cousteau, Co-Founder and CEO, EarthEcho International Manuel Alberto Diaz, Partner...

PC-403: Pioneer Venus multiprobe spacecraft mission operational characteristics document, volume 2

NASA Technical Reports Server (NTRS)

Barker, F. C.

1978-01-01

The data handling subsystem, command subsystem, communications subsystem, power subsystem, and mission operations of the Pioneer Venus multiprobe are presented. The multiprobe spacecraft performance in normal operating modes that correspond to the performance of specific functions at the time of specific events in the mission is described.

Protocol for communications in potentially noisy environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyd, Gerlad M.; Farrow, Jeffrey

2016-02-09

A communications protocol that is designed for transmission of data in networks that are subjected to harsh conditions is described herein. A network includes a plurality of devices, where the devices comprise respective nodes. The nodes are in communication with one another by way of a central network hub. The protocol causes the nodes to transmit data over a network bus at different data rates depending upon whether the nodes are operating normally or an arbitration procedure has been invoked.

Identifying messaging completion in a parallel computer by checking for change in message received and transmitted count at each node

DOEpatents

Archer, Charles J [Rochester, MN; Hardwick, Camesha R [Fayetteville, NC; McCarthy, Patrick J [Rochester, MN; Wallenfelt, Brian P [Eden Prairie, MN

2009-06-23

Methods, parallel computers, and products are provided for identifying messaging completion on a parallel computer. The parallel computer includes a plurality of compute nodes, the compute nodes coupled for data communications by at least two independent data communications networks including a binary tree data communications network optimal for collective operations that organizes the nodes as a tree and a torus data communications network optimal for point to point operations that organizes the nodes as a torus. Embodiments include reading all counters at each node of the torus data communications network; calculating at each node a current node value in dependence upon the values read from the counters at each node; and determining for all nodes whether the current node value for each node is the same as a previously calculated node value for each node. If the current node is the same as the previously calculated node value for all nodes of the torus data communications network, embodiments include determining that messaging is complete and if the current node is not the same as the previously calculated node value for all nodes of the torus data communications network, embodiments include determining that messaging is currently incomplete.

The Geospatial Characteristics of a Social Movement Communication Network

PubMed Central

Conover, Michael D.; Davis, Clayton; Ferrara, Emilio; McKelvey, Karissa; Menczer, Filippo; Flammini, Alessandro

2013-01-01

Social movements rely in large measure on networked communication technologies to organize and disseminate information relating to the movements’ objectives. In this work we seek to understand how the goals and needs of a protest movement are reflected in the geographic patterns of its communication network, and how these patterns differ from those of stable political communication. To this end, we examine an online communication network reconstructed from over 600,000 tweets from a thirty-six week period covering the birth and maturation of the American anticapitalist movement, Occupy Wall Street. We find that, compared to a network of stable domestic political communication, the Occupy Wall Street network exhibits higher levels of locality and a hub and spoke structure, in which the majority of non-local attention is allocated to high-profile locations such as New York, California, and Washington D.C. Moreover, we observe that information flows across state boundaries are more likely to contain framing language and references to the media, while communication among individuals in the same state is more likely to reference protest action and specific places and times. Tying these results to social movement theory, we propose that these features reflect the movement’s efforts to mobilize resources at the local level and to develop narrative frames that reinforce collective purpose at the national level. PMID:23483885

The geospatial characteristics of a social movement communication network.

PubMed

Conover, Michael D; Davis, Clayton; Ferrara, Emilio; McKelvey, Karissa; Menczer, Filippo; Flammini, Alessandro

2013-01-01

Social movements rely in large measure on networked communication technologies to organize and disseminate information relating to the movements' objectives. In this work we seek to understand how the goals and needs of a protest movement are reflected in the geographic patterns of its communication network, and how these patterns differ from those of stable political communication. To this end, we examine an online communication network reconstructed from over 600,000 tweets from a thirty-six week period covering the birth and maturation of the American anticapitalist movement, Occupy Wall Street. We find that, compared to a network of stable domestic political communication, the Occupy Wall Street network exhibits higher levels of locality and a hub and spoke structure, in which the majority of non-local attention is allocated to high-profile locations such as New York, California, and Washington D.C. Moreover, we observe that information flows across state boundaries are more likely to contain framing language and references to the media, while communication among individuals in the same state is more likely to reference protest action and specific places and times. Tying these results to social movement theory, we propose that these features reflect the movement's efforts to mobilize resources at the local level and to develop narrative frames that reinforce collective purpose at the national level.

Optical interconnection network for parallel access to multi-rank memory in future computing systems.

PubMed

Wang, Kang; Gu, Huaxi; Yang, Yintang; Wang, Kun

2015-08-10

With the number of cores increasing, there is an emerging need for a high-bandwidth low-latency interconnection network, serving core-to-memory communication. In this paper, aiming at the goal of simultaneous access to multi-rank memory, we propose an optical interconnection network for core-to-memory communication. In the proposed network, the wavelength usage is delicately arranged so that cores can communicate with different ranks at the same time and broadcast for flow control can be achieved. A distributed memory controller architecture that works in a pipeline mode is also designed for efficient optical communication and transaction address processes. The scaling method and wavelength assignment for the proposed network are investigated. Compared with traditional electronic bus-based core-to-memory communication, the simulation results based on the PARSEC benchmark show that the bandwidth enhancement and latency reduction are apparent.

A synthetic mammalian network to compute population borders based on engineered reciprocal cell-cell communication.

PubMed

Kolar, Katja; Wischhusen, Hanna M; Müller, Konrad; Karlsson, Maria; Weber, Wilfried; Zurbriggen, Matias D

2015-12-30

Multicellular organisms depend on the exchange of information between specialized cells. This communication is often difficult to decipher in its native context, but synthetic biology provides tools to engineer well-defined systems that allow the convenient study and manipulation of intercellular communication networks. Here, we present the first mammalian synthetic network for reciprocal cell-cell communication to compute the border between a sender/receiver and a processing cell population. The two populations communicate via L-tryptophan and interleukin-4 to highlight the population border by the production of a fluorescent protein. The sharpness of that visualized edge can be adjusted by modulating key parameters of the network. We anticipate that this network will on the one hand be a useful tool to gain deeper insights into the mechanisms of tissue formation in nature and will on the other hand contribute to our ability to engineer artificial tissues.

Communication, opponents, and clan performance in online games: a social network approach.

PubMed

Lee, Hong Joo; Choi, Jaewon; Kim, Jong Woo; Park, Sung Joo; Gloor, Peter

2013-12-01

Online gamers form clans voluntarily to play together and to discuss their real and virtual lives. Although these clans have diverse goals, they seek to increase their rank in the game community by winning more battles. Communications among clan members and battles with other clans may influence the performance of a clan. In this study, we compared the effects of communication structure inside a clan, and battle networks among clans, with the performance of the clans. We collected battle histories, posts, and comments on clan pages from a Korean online game, and measured social network indices for communication and battle networks. Communication structures in terms of density and group degree centralization index had no significant association with clan performance. However, the centrality of clans in the battle network was positively related to the performance of the clan. If a clan had many battle opponents, the performance of the clan improved.

Communication, Opponents, and Clan Performance in Online Games: A Social Network Approach

PubMed Central

Lee, Hong Joo; Choi, Jaewon; Park, Sung Joo; Gloor, Peter

2013-01-01

Abstract Online gamers form clans voluntarily to play together and to discuss their real and virtual lives. Although these clans have diverse goals, they seek to increase their rank in the game community by winning more battles. Communications among clan members and battles with other clans may influence the performance of a clan. In this study, we compared the effects of communication structure inside a clan, and battle networks among clans, with the performance of the clans. We collected battle histories, posts, and comments on clan pages from a Korean online game, and measured social network indices for communication and battle networks. Communication structures in terms of density and group degree centralization index had no significant association with clan performance. However, the centrality of clans in the battle network was positively related to the performance of the clan. If a clan had many battle opponents, the performance of the clan improved. PMID:23745617

A wireless medical monitoring over a heterogeneous sensor network.

PubMed

Yuce, Mehmet R; Ng, Peng Choong; Lee, Chin K; Khan, Jamil Y; Liu, Wentai

2007-01-01

This paper presents a heterogeneous sensor network system that has the capability to monitor physiological parameters from multiple patient bodies by means of different communication standards. The system uses the recently opened medical band called MICS (Medical Implant Communication Service) between the sensor nodes and a remote central control unit (CCU) that behaves as a base station. The CCU communicates with another network standard (the internet or a mobile network) for a long distance data transfer. The proposed system offers mobility to patients and flexibility to medical staff to obtain patient's physiological data on demand basis via Internet. A prototype sensor network including hardware, firmware and software designs has been implemented and tested by incorporating temperature and pulse rate sensors on nodes. The developed system has been optimized for power consumption by having the nodes sleep when there is no communication via a bidirectional communication.

Risk management communication system between a local government and residents using several network systems and terminal devices

NASA Astrophysics Data System (ADS)

Ohyama, Takashi; Enomoto, Hiroyuki; Takei, Yuichiro; Maeda, Yuji

2009-05-01

Most of Japan's local governments utilize municipal disaster-management radio communications systems to communicate information on disasters or terrorism to residents. The national government is progressing in efforts toward digitalization by local governments of these systems, but only a small number (approx. 10%) have introduced such equipment due to its requiring large amounts of investment. On the other hand, many local governments are moving forward in installation of optical fiber networks for the purpose of eliminating the "digital divide." We herein propose a communication system as an alternative or supplement to municipal disaster-management radio communications systems, which utilizes municipal optical fiber networks, the internet and similar networks and terminals. The system utilizes the multiple existing networks and is capable of instantly distributing to all residents, and controlling, risk management information. We describe the system overview and the field trials conducted with a local government using this system.

Synchrophasor Sensor Networks for Grid Communication and Protection.

PubMed

Gharavi, Hamid; Hu, Bin

2017-07-01

This paper focuses primarily on leveraging synchronized current/voltage amplitudes and phase angle measurements to foster new categories of applications, such as improving the effectiveness of grid protection and minimizing outage duration for distributed grid systems. The motivation for such an application arises from the fact that with the support of communication, synchronized measurements from multiple sites in a grid network can greatly enhance the accuracy and timeliness of identifying the source of instabilities. The paper first provides an overview of synchrophasor networks and then presents techniques for power quality assessment, including fault detection and protection. To achieve this we present a new synchrophasor data partitioning scheme that is based on the formation of a joint space and time observation vector. Since communication is an integral part of synchrophasor networks, the newly adopted wireless standard for machine-to-machine (M2M) communication, known as IEEE 802.11ah, has been investigated. The paper also presents a novel implementation of a hardware in the loop testbed for real-time performance evaluation. The purpose is to illustrate the use of both hardware and software tools to verify the performance of synchrophasor networks under more realistic environments. The testbed is a combination of grid network modeling, and an Emulab-based communication network. The combined grid and communication network is then used to assess power quality for fault detection and location using the IEEE 39-bus and 390-bus systems.

Synchrophasor Sensor Networks for Grid Communication and Protection

PubMed Central

Gharavi, Hamid

2017-01-01

This paper focuses primarily on leveraging synchronized current/voltage amplitudes and phase angle measurements to foster new categories of applications, such as improving the effectiveness of grid protection and minimizing outage duration for distributed grid systems. The motivation for such an application arises from the fact that with the support of communication, synchronized measurements from multiple sites in a grid network can greatly enhance the accuracy and timeliness of identifying the source of instabilities. The paper first provides an overview of synchrophasor networks and then presents techniques for power quality assessment, including fault detection and protection. To achieve this we present a new synchrophasor data partitioning scheme that is based on the formation of a joint space and time observation vector. Since communication is an integral part of synchrophasor networks, the newly adopted wireless standard for machine-to-machine (M2M) communication, known as IEEE 802.11ah, has been investigated. The paper also presents a novel implementation of a hardware in the loop testbed for real-time performance evaluation. The purpose is to illustrate the use of both hardware and software tools to verify the performance of synchrophasor networks under more realistic environments. The testbed is a combination of grid network modeling, and an Emulab-based communication network. The combined grid and communication network is then used to assess power quality for fault detection and location using the IEEE 39-bus and 390-bus systems. PMID:28890553

Technology Developments Integrating a Space Network Communications Testbed

NASA Technical Reports Server (NTRS)

Kwong, Winston; Jennings, Esther; Clare, Loren; Leang, Dee

2006-01-01

As future manned and robotic space explorations missions involve more complex systems, it is essential to verify, validate, and optimize such systems through simulation and emulation in a low cost testbed environment. The goal of such a testbed is to perform detailed testing of advanced space and ground communications networks, technologies, and client applications that are essential for future space exploration missions. We describe the development of new technologies enhancing our Multi-mission Advanced Communications Hybrid Environment for Test and Evaluation (MACHETE) that enable its integration in a distributed space communications testbed. MACHETE combines orbital modeling, link analysis, and protocol and service modeling to quantify system performance based on comprehensive considerations of different aspects of space missions. It can simulate entire networks and can interface with external (testbed) systems. The key technology developments enabling the integration of MACHETE into a distributed testbed are the Monitor and Control module and the QualNet IP Network Emulator module. Specifically, the Monitor and Control module establishes a standard interface mechanism to centralize the management of each testbed component. The QualNet IP Network Emulator module allows externally generated network traffic to be passed through MACHETE to experience simulated network behaviors such as propagation delay, data loss, orbital effects and other communications characteristics, including entire network behaviors. We report a successful integration of MACHETE with a space communication testbed modeling a lunar exploration scenario. This document is the viewgraph slides of the presentation.

High speed fault tolerant secure communication for muon chamber using FPGA based GBTx emulator

NASA Astrophysics Data System (ADS)

Sau, Suman; Mandal, Swagata; Saini, Jogender; Chakrabarti, Amlan; Chattopadhyay, Subhasis

2015-12-01

The Compressed Baryonic Matter (CBM) experiment is a part of the Facility for Antiproton and Ion Research (FAIR) in Darmstadt at the GSI. The CBM experiment will investigate the highly compressed nuclear matter using nucleus-nucleus collisions. This experiment will examine lieavy-ion collisions in fixed target geometry and will be able to measure hadrons, electrons and muons. CBM requires precise time synchronization, compact hardware, radiation tolerance, self-triggered front-end electronics, efficient data aggregation schemes and capability to handle high data rate (up to several TB/s). As a part of the implementation of read out chain of Muon Cliamber(MUCH) [1] in India, we have tried to implement FPGA based emulator of GBTx in India. GBTx is a radiation tolerant ASIC that can be used to implement multipurpose high speed bidirectional optical links for high-energy physics (HEP) experiments and is developed by CERN. GBTx will be used in highly irradiated area and more prone to be affected by multi bit error. To mitigate this effect instead of single bit error correcting RS code we have used two bit error correcting (15, 7) BCH code. It will increase the redundancy which in turn increases the reliability of the coded data. So the coded data will be less prone to be affected by noise due to radiation. The data will go from detector to PC through multiple nodes through the communication channel. The computing resources are connected to a network which can be accessed by authorized person to prevent unauthorized data access which might happen by compromising the network security. Thus data encryption is essential. In order to make the data communication secure, advanced encryption standard [2] (AES - a symmetric key cryptography) and RSA [3], [4] (asymmetric key cryptography) are used after the channel coding. We have implemented GBTx emulator on two Xilinx Kintex-7 boards (KC705). One will act as transmitter and other will act as receiver and they are connected through optical fiber through small form-factor pluggable (SFP) port. We have tested the setup in the runtime environment using Xilinx Cliipscope Pro Analyzer. We also measure the resource utilization, throughput., power optimization of implemented design.

Future Plans for NASA's Deep Space Network

NASA Technical Reports Server (NTRS)

Deutsch, Leslie J.; Preston, Robert A.; Geldzahler, Barry J.

2008-01-01

This slide presentation reviews the importance of NASA's Deep Space Network (DSN) to space exploration, and future planned improvements to the communication capabilities that the network allows, in terms of precision, and communication power.

Communication efficiency and congestion of signal traffic in large-scale brain networks.

PubMed

Mišić, Bratislav; Sporns, Olaf; McIntosh, Anthony R

2014-01-01

The complex connectivity of the cerebral cortex suggests that inter-regional communication is a primary function. Using computational modeling, we show that anatomical connectivity may be a major determinant for global information flow in brain networks. A macaque brain network was implemented as a communication network in which signal units flowed between grey matter nodes along white matter paths. Compared to degree-matched surrogate networks, information flow on the macaque brain network was characterized by higher loss rates, faster transit times and lower throughput, suggesting that neural connectivity may be optimized for speed rather than fidelity. Much of global communication was mediated by a "rich club" of hub regions: a sub-graph comprised of high-degree nodes that are more densely interconnected with each other than predicted by chance. First, macaque communication patterns most closely resembled those observed for a synthetic rich club network, but were less similar to those seen in a synthetic small world network, suggesting that the former is a more fundamental feature of brain network topology. Second, rich club regions attracted the most signal traffic and likewise, connections between rich club regions carried more traffic than connections between non-rich club regions. Third, a number of rich club regions were significantly under-congested, suggesting that macaque connectivity actively shapes information flow, funneling traffic towards some nodes and away from others. Together, our results indicate a critical role of the rich club of hub nodes in dynamic aspects of global brain communication.

Communication Efficiency and Congestion of Signal Traffic in Large-Scale Brain Networks

PubMed Central

Mišić, Bratislav; Sporns, Olaf; McIntosh, Anthony R.

2014-01-01

The complex connectivity of the cerebral cortex suggests that inter-regional communication is a primary function. Using computational modeling, we show that anatomical connectivity may be a major determinant for global information flow in brain networks. A macaque brain network was implemented as a communication network in which signal units flowed between grey matter nodes along white matter paths. Compared to degree-matched surrogate networks, information flow on the macaque brain network was characterized by higher loss rates, faster transit times and lower throughput, suggesting that neural connectivity may be optimized for speed rather than fidelity. Much of global communication was mediated by a “rich club” of hub regions: a sub-graph comprised of high-degree nodes that are more densely interconnected with each other than predicted by chance. First, macaque communication patterns most closely resembled those observed for a synthetic rich club network, but were less similar to those seen in a synthetic small world network, suggesting that the former is a more fundamental feature of brain network topology. Second, rich club regions attracted the most signal traffic and likewise, connections between rich club regions carried more traffic than connections between non-rich club regions. Third, a number of rich club regions were significantly under-congested, suggesting that macaque connectivity actively shapes information flow, funneling traffic towards some nodes and away from others. Together, our results indicate a critical role of the rich club of hub nodes in dynamic aspects of global brain communication. PMID:24415931

Light-induced crosslinkable semiconducting polymer dots† †Electronic supplementary information (ESI) available: Synthesis and characterization of monomers and polymers, preparation and characterization of thin film and Pdots, optical property measurements and flow cytometry is available. See DOI: 10.1039/c4sc03959a Click here for additional data file.

PubMed Central

Zhang, Yue; Ye, Fangmao; Sun, Wei; Yu, Jiangbo; Wu, I-Che; Rong, Yu; Zhang, Yong

2015-01-01

This paper describes a synthetic approach for photocrosslinkable polyfluorene (pc-PFO) semiconducting polymer dots, and demonstrates their superior ability to crosslink and form 3-D intermolecular polymer networks. The crosslinked pc-PFO Pdots are equipped with excellent encapsulating ability of functional small molecules. Optimum conditions of light irradiation on pc-PFO Pdots were investigated and clarified by using polymer thin films as a model. By employing the optimal light irradiation conditions, we successfully crosslinked pc-PFO Pdots and studied their particle sizes, photophysical, and colloidal properties. Single-particle imaging and dynamic-light-scattering measurements were conducted to understand the behaviors of photocrosslinked Pdots. Our results indicate pc-PFO Pdots can be easily photocrosslinked and the crosslinked species have excellent colloidal stability, physical and chemical stability, fluorescence brightness, and specific binding properties for cellular labeling. Considering that optical stimulus can work remotely, cleanly, and non-invasively, this study should pave the way for a promising approach to further develop stimuli-responsive ultrabright and versatile Pdot probes for biomedical imaging. PMID:25709806

DDN (Defense Data Network) Protocol Implementations and Vendors Guide

DTIC Science & Technology

1989-02-01

Announcement 286-259 6/16/86 MACHINE-TYPE/CPU: IBM RT/PC O/S: AIX DISTRIBUTOR: 1. IBM Marketing 2. IBM Authorized VAR’s 3. Authorized Personal Computer...Vendors Guide 12. PERSONAL AUTHOR(S) Dorio, Nan; Johnson, Marlyn; Lederman. Sol; Redfield, Elizabeth; Ward, Carol 13a. TYPE OF REPORT 13b. TIME COVERED 114...documentation, contact person , and distributor. The fourth section describes analysis tools. It includes information about network analysis products

Transcriptional Networks in Single Perivascular Cells Sorted from Human Adipose Tissue Reveal a Hierarchy of Mesenchymal Stem Cells.

PubMed

Hardy, W Reef; Moldovan, Nicanor I; Moldovan, Leni; Livak, Kenneth J; Datta, Krishna; Goswami, Chirayu; Corselli, Mirko; Traktuev, Dmitry O; Murray, Iain R; Péault, Bruno; March, Keith

2017-05-01

Adipose tissue is a rich source of multipotent mesenchymal stem-like cells, located in the perivascular niche. Based on their surface markers, these have been assigned to two main categories: CD31 - /CD45 - /CD34 + /CD146 - cells (adventitial stromal/stem cells [ASCs]) and CD31 - /CD45 - /CD34 - /CD146 + cells (pericytes [PCs]). These populations display heterogeneity of unknown significance. We hypothesized that aldehyde dehydrogenase (ALDH) activity, a functional marker of primitivity, could help to better define ASC and PC subclasses. To this end, the stromal vascular fraction from a human lipoaspirate was simultaneously stained with fluorescent antibodies to CD31, CD45, CD34, and CD146 antigens and the ALDH substrate Aldefluor, then sorted by fluorescence-activated cell sorting. Individual ASCs (n = 67) and PCs (n = 73) selected from the extremities of the ALDH-staining spectrum were transcriptionally profiled by Fluidigm single-cell quantitative polymerase chain reaction for a predefined set (n = 429) of marker genes. To these single-cell data, we applied differential expression and principal component and clustering analysis, as well as an original gene coexpression network reconstruction algorithm. Despite the stochasticity at the single-cell level, covariation of gene expression analysis yielded multiple network connectivity parameters suggesting that these perivascular progenitor cell subclasses possess the following order of maturity: (a) ALDH br ASC (most primitive); (b) ALDH dim ASC; (c) ALDH br PC; (d) ALDH dim PC (least primitive). This order was independently supported by specific combinations of class-specific expressed genes and further confirmed by the analysis of associated signaling pathways. In conclusion, single-cell transcriptional analysis of four populations isolated from fat by surface markers and enzyme activity suggests a developmental hierarchy among perivascular mesenchymal stem cells supported by markers and coexpression networks. Stem Cells 2017;35:1273-1289. © 2017 AlphaMed Press.