Sample records for peel wastes valencia

  1. Improvement of biogas production from orange peel waste by leaching of limonene.

    PubMed

    Wikandari, Rachma; Nguyen, Huong; Millati, Ria; Niklasson, Claes; Taherzadeh, Mohammad J

    2015-01-01

    Limonene is present in orange peel wastes and is known as an antimicrobial agent, which impedes biogas production when digesting the peels. In this work, pretreatment of the peels to remove limonene under mild condition was proposed by leaching of limonene using hexane as solvent. The pretreatments were carried out with homogenized or chopped orange peel at 20-40°C with orange peel waste and hexane ratio (w/v) ranging from 1 : 2 to 1 : 12 for 10 to 300 min. The pretreated peels were then digested in batch reactors for 33 days. The highest biogas production was achieved by treating chopped orange peel waste and hexane ratio of 12 : 1 at 20°C for 10 min corresponding to more than threefold increase of biogas production from 0.061 to 0.217 m(3) methane/kg VS. The solvent recovery was 90% using vacuum filtration and needs further separation using evaporation. The hexane residue in the peel had a negative impact on biogas production as shown by 28.6% reduction of methane and lower methane production of pretreated orange peel waste in semicontinuous digestion system compared to that of untreated peel.

  2. Improvement of Biogas Production from Orange Peel Waste by Leaching of Limonene

    PubMed Central

    Wikandari, Rachma; Nguyen, Huong; Millati, Ria; Niklasson, Claes; Taherzadeh, Mohammad J.

    2015-01-01

    Limonene is present in orange peel wastes and is known as an antimicrobial agent, which impedes biogas production when digesting the peels. In this work, pretreatment of the peels to remove limonene under mild condition was proposed by leaching of limonene using hexane as solvent. The pretreatments were carried out with homogenized or chopped orange peel at 20–40°C with orange peel waste and hexane ratio (w/v) ranging from 1 : 2 to 1 : 12 for 10 to 300 min. The pretreated peels were then digested in batch reactors for 33 days. The highest biogas production was achieved by treating chopped orange peel waste and hexane ratio of 12 : 1 at 20°C for 10 min corresponding to more than threefold increase of biogas production from 0.061 to 0.217 m3 methane/kg VS. The solvent recovery was 90% using vacuum filtration and needs further separation using evaporation. The hexane residue in the peel had a negative impact on biogas production as shown by 28.6% reduction of methane and lower methane production of pretreated orange peel waste in semicontinuous digestion system compared to that of untreated peel. PMID:25866787

  3. Citric Acid Production from Orange Peel Wastes by Solid-State Fermentation

    PubMed Central

    Torrado, Ana María; Cortés, Sandra; Manuel Salgado, José; Max, Belén; Rodríguez, Noelia; Bibbins, Belinda P.; Converti, Attilio; Manuel Domínguez, José

    2011-01-01

    Valencia orange (Citrus sinensis) peel was employed in this work as raw material for the production of citric acid (CA) by solid-state fermentation (SSF) of Aspergillus niger CECT-2090 (ATCC 9142, NRRL 599) in Erlenmeyer flasks. To investigate the effects of the main operating variables, the inoculum concentration was varied in the range 0.5·103 to 0.7·108 spores/g dry orange peel, the bed loading from 1.0 to 4.8 g of dry orange peel (corresponding to 35-80 % of the total volume), and the moisture content between 50 and 100 % of the maximum water retention capacity (MWRC) of the material. Moreover, additional experiments were done adding methanol or water in different proportions and ways. The optimal conditions for CA production revealed to be an inoculum of 0.5·106 spores/g dry orange peel, a bed loading of 1.0 g of dry orange peel, and a humidification pattern of 70 % MWRC at the beginning of the incubation with posterior addition of 0.12 mL H2O/g dry orange peel (corresponding to 3.3 % of the MWRC) every 12 h starting from 62 h. The addition of methanol was detrimental for the CA production. Under these conditions, the SSF ensured an effective specific production of CA (193 mg CA/g dry orange peel), corresponding to yields of product on total initial and consumed sugars (glucose, fructose and sucrose) of 376 and 383 mg CA/g, respectively. These results, which demonstrate the viability of the CA production by SSF from orange peel without addition of other nutrients, could be of interest to possible, future industrial applications. PMID:24031646

  4. Impact of biochar on the anaerobic digestion of citrus peel waste.

    PubMed

    Fagbohungbe, Michael O; Herbert, Ben M J; Hurst, Lois; Li, Hong; Usmani, Shams Q; Semple, Kirk T

    2016-09-01

    In this study, the impact of different types of biochar and biochar ratios on the anaerobic digestion of citrus peel waste was investigated. Citrus peel has an inhibitory effect on anaerobic digestion. The presence of biochar had two effects: a reduction in the length of the lag phase and greater production of methane relative to citrus peel waste only incubations. The microbial lag phases decreased with increase in citrus peel to biochar ratios, with 2:1 having the longest lag phase of 9.4days and 1:3, the shortest, with the value of 7.5days. The cumulative methane production in incubations containing biochar and citrus peel ranged from 163.9 to 186.8ml CH4 gVS(-1), while citrus peel only produced 165.9ml CH4 gVS(-1). Examination of the biochar material revealed colonies of putative methanogens. The synergy of d-limonene adsorption and microbial immobilization by biochar appears to improve the performance of anaerobic digestion. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Quantification of Transfer of Salmonella from Citrus Fruits to Peel, Edible Portion, and Gloved Hands during Hand Peeling.

    PubMed

    Jung, Jiin; Friedrich, Loretta M; Danyluk, Michelle D; Schaffner, Donald W

    2017-06-01

    Although studies have quantified bacterial transfer between hands and various materials, cross-contamination between the surface of fresh citrus fruit and the edible portions during hand peeling has not been reported. This study quantifies transfer of Salmonella to the edible portion of citrus fruit from a contaminated peel during hand peeling. Citrus fruits used for this study were Citrus sinensis (sweet orange) cultivars 'Valencia' and 'Navel', Citrus unshiu (Satsuma mandarins), Citrus reticulata × Citrus paradisi ('Minneola' tangelo or 'Honeybell'), and C. paradisi (grapefruit) cultivar 'Marsh'. An avirulent Salmonella Typhimurium LT2 (ATCC 700720) resistant to rifampin was used for all experiments. The inoculum containing approximately 9 log CFU/mL (50 μL) was spot inoculated onto the equator, stem, or styler of each fruit and allowed to dry for 24 h. Six volunteers put on single-use latex gloves and peeled inoculated fruit. Peel, edible fruit portion, and gloves were collected and enumerated separately. Three replicates of the study were performed in which each volunteer peeled two inoculated fruit of each variety (n = 36 fruit per variety). Cross-contamination from contaminated surface of citrus fruits to edible portion or gloved hands during peeling was affected by inoculation sites. Average Salmonella transfer to the edible portion ranged from 0.16% (Valencia inoculated at the equator) to 5.41% (navel inoculated at the stem). Average Salmonella transfer to gloved hands ranged from 0.41% (grapefruit inoculated at the stem) to 8.97% (navel inoculated at the stem). Most Salmonella remained on the peel of citrus fruits. The average level of Salmonella remaining on the peel ranged from 5.37% (Minneola inoculated at the equator) to 66.3% (Satsuma inoculated at the styler). When grapefruit was inoculated, the Salmonella that remained on the peel showed a bimodal pattern in which some individuals left almost all Salmonella on the peel, while others left

  6. Characterization of a polyhydroxyalkanoate obtained from pineapple peel waste using Ralsthonia eutropha.

    PubMed

    Vega-Castro, Oscar; Contreras-Calderon, Jose; León, Emilson; Segura, Almir; Arias, Mario; Pérez, León; Sobral, Paulo J A

    2016-08-10

    Agro-industrial waste can be the production source of biopolymers such as polyhydroxyalkanoates. The aim of this study was to produce and characterize Polyhydroxyalkanoates produced from pineapple peel waste fermentation processes. The methodology includes different pineapple peel waste fermentation conditions. The produced biopolymer was characterized using FTIR, GC-MS and NMR. The best fermentation condition for biopolymer production was obtained using pH 9, Carbon/Nitrogen 11, carbon/phosphorus 6 and fermentation time of 60h. FTIR analyzes showed PHB group characteristics, such as OH, CH and CO. In addition, GC-MS showed two monomers with 4 and 8 carbons, referred to PHB and PHBHV. H(1) NMR analysis showed 0.88-0.97 and 5.27ppm signals, corresponding to CH3 and CH, respectively. In conclusion, polyhydroxyalkanoate production from pineapple peels waste is an alternative for the treatment of waste generated in Colombia's fruit industry. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Synergistic effect of co-digestion to enhance anaerobic degradation of catering waste and orange peel for biogas production.

    PubMed

    Anjum, Muzammil; Khalid, Azeem; Qadeer, Samia; Miandad, Rashid

    2017-09-01

    Catering waste and orange peel were co-digested using an anaerobic digestion process. Orange peel is difficult to degrade anaerobically due to the presence of antimicrobial agents such as limonene. The present study aimed to examine the feasibility of anaerobic co-digestion of catering waste with orange peel to provide the optimum nutrient balance with reduced inhibitory effects of orange peel. Batch experiments were conducted using catering waste as a potential substrate mixed in varying ratios (20-50%) with orange peel. Similar ratios were followed using green vegetable waste as co-substrate. The results showed that the highest organic matter degradation (49%) was achieved with co-digestion of catering waste and orange peel at a 50% mixing ratio (CF4). Similarly, the soluble chemical oxygen demand (sCOD) was increased by 51% and reached its maximum value (9040 mg l -1 ) due to conversion of organic matter from insoluble to soluble form. Biogas production was increased by 1.5 times in CF4 where accumulative biogas was 89.61 m 3 t -1 substrate compared with 57.35 m 3 t -1 substrate in the control after 80 days. The main reason behind the improved biogas production and degradation is the dilution of inhibitory factors (limonene), with subsequent provision of balanced nutrients in the co-digestion system. The tCOD of the final digestate was decreased by 79.9% in CF4, which was quite high as compared with 68.3% for the control. Overall, this study revealed that orange peel waste is a highly feasible co-substrate for anaerobic digestion with catering waste for enhanced biogas production.

  8. A Pontential Agriculture Waste Material as Coagulant Aid: Cassava Peel

    NASA Astrophysics Data System (ADS)

    Othman, N.; Abd-Rahim, N.-S.; Tuan-Besar, S.-N.-F.; Mohd-Asharuddin, S.; Kumar, V.

    2018-02-01

    All A large amount of cassava peel waste is generated annually by small and medium scale industries. This has led to a new policy of complete utilization of raw materials so that there will be little or no residue left that could pose pollution problems. Conversion of these by-products into a material that poses an ability to remove toxic pollutant would increase the market value and ultimately benefits the producers. This study investigated the characteristics of cassava peel as a coagulant aid material and optimization process using the cassava peel was explored through coagulation and flocculation. This research had highlighted that the Cassava peels contain sugars in the form of polysaccharides such as starch and holocellulose. The FTIR results revealed that amino acids containing abundant of carboxyl, hydroxyl and amino groups which has significant capabilities in removing pollutants. Whereas analysis by XRF spectrometry indicated that the CP samples contain Fe2O3 and Al2O3 which might contribute to its coagulation ability. The optimum condition allowed Cassava peel and alum removed high turbidity up to 90. This natural coagulant from cassava peel is found to be an alternative coagulant aid to reduce the usage of chemical coagulants

  9. Studies on mould growth and biomass production using waste banana peel.

    PubMed

    Essien, J P; Akpan, E J; Essien, E P

    2005-09-01

    Hyphomycetous (Aspergillus fumigatus) and Phycomycetous (Mucor hiemalis) moulds were cultivated in vitro at room temperature (28 + 20 degrees C) to examined their growth and biomass production on waste banana peel agar (BPA) and broth (BPB) using commercial malt extract agar (MEA) and broth (MEB) as control. The moulds grew comparatively well on banana peel substrates. No significant difference (p > 0.05) in radial growth rates was observed between moulds cultivated on PBA and MEA, although growth rates on MEA were slightly better. Slight variations in sizes of asexual spores and reproductive hyphae were also observed between moulds grown on MEA and BPA. Smaller conidia and sporangiospores, and shorter aerial hyphae (conidiophores and sporangiophores) were noticed in moulds grown on BPA than on MEA. The biomass weight of the test moulds obtained after one month of incubation with BPB were only about 1.8 mg and 1.4 mg less than values recorded for A. fumigatus and M. hiemalis respectively, grown on MEB. The impressive performance of the moulds on banana peel substrate may be attributed to the rich nutrient (particularly the crude protein 7.8% and crude fat 11.6% contents) composition of banana peels. The value of this agricultural waste can therefore be increased by its use not only in the manufacture of mycological medium but also in the production of valuable microfungal biomass which is rich in protein and fatty acids.

  10. Unavoidable food supply chain waste: acid-free pectin extraction from mango peel via subcritical water.

    PubMed

    Xia, H; Matharu, A S

    2017-09-21

    Mango peel is the major by-product of mango processing, and compromises 7-24% of the total mango weight. In this study, pectin was extracted from mango peel waste by using subcritical water extraction (SWE) in the absence of mineral acid. A highest yield of 18.34% was achieved from the Kesar variety and the pectin was characterised using ATR-IR spectroscopy, TGA and 13 C solid-state NMR spectroscopy to confirm the structure. The degree of esterification (DE) of the pectin was analysed with both titrimetry and 13 C solid-state NMR spectroscopy, and a high DE (>70%) was observed for all three varieties (Keitt, Sindhri and Kesar). This is the first report on acid-free subcritical water extraction of pectin from mango peel, which provides a green route for the valorisation of mango peel waste and contributes to a source of biobased materials and chemicals for a sustainable 21 st century.

  11. Optimization of fermentation parameters for production of ethanol from kinnow waste and banana peels by simultaneous saccharification and fermentation.

    PubMed

    Sharma, Naresh; Kalra, K L; Oberoi, Harinder Singh; Bansal, Sunil

    2007-12-01

    A study was taken up to evaluate the role of some fermentation parameters like inoculum concentration, temperature, incubation period and agitation time on ethanol production from kinnow waste and banana peels by simultaneous saccharification and fermentation using cellulase and co-culture of Saccharomyces cerevisiae G and Pachysolen tannophilus MTCC 1077. Steam pretreated kinnow waste and banana peels were used as substrate for ethanol production in the ratio 4:6 (kinnow waste: banana peels). Temperature of 30°C, inoculum size of S. cerevisiae G 6% and (v/v) Pachysolen tannophilus MTCC 1077 4% (v/v), incubation period of 48 h and agitation for the first 24 h were found to be best for ethanol production using the combination of two wastes. The pretreated steam exploded biomass after enzymatic saccharification containing 63 gL(-1) reducing sugars was fermented with both hexose and pentose fermenting yeast strains under optimized conditions resulting in ethanol production, yield and fermentation efficiency of 26.84 gL(-1), 0.426 gg (-1) and 83.52 % respectively. This study could establish the effective utilization of kinnow waste and banana peels for bioethanol production using optimized fermentation parameters.

  12. Preparation and Characterization of Cellulose and Nanocellulose from Agro-industrial Waste - Cassava Peel

    NASA Astrophysics Data System (ADS)

    Widiarto, S.; Yuwono, S. D.; Rochliadi, A.; Arcana, I. M.

    2017-02-01

    Cassava peel is an agro-industrial waste which is available in huge quantities in Lampung Province of Indonesia. This work was conducted to evaluate the potential of cassava peel as a source of cellulose and nanocellulose. Cellulose was extracted from cassava peel by using different chemical treatment, and the nanocellulose was prepared by hydrolysis with the use of sulfuric acid. The best methods of cellulose extraction from cassava peels are using alkali treatment followed by a bleaching process. The cellulose yield from this methods was 17.8% of dry base cassava peel, while the yield from nitric and sulfuric methods were about 10.78% and 10.32% of dry base cassava peel respectively. The hydrolysis was performed at the temperature of 50 °C for 2 hours. The intermediate reaction product obtained after each stage of the treatments was characterized. Fourier transform infrared spectroscopy showed the removal of non-cellulosic constituent. X-ray Diffraction (XRD) analysis revealed that the crystallinity of cellulose increased after hydrolysis. Morphological investigation was performed using Scanning Electron Microscopy (SEM). The size of particle was confirmed by Particle Size Analyzer (PSA) and Transmission Electron Microscopy (TEM).

  13. Pineapple peel wastes as a potential source of antioxidant compounds

    NASA Astrophysics Data System (ADS)

    Saraswaty, V.; Risdian, C.; Primadona, I.; Andriyani, R.; Andayani, D. G. S.; Mozef, T.

    2017-03-01

    Indonesia is a large pineapple (Ananas comosus) producing country. Food industries in Indonesia processed this fruit for new products and further resulted wastes of which cause an environmental problems. Approximately, one pineapple fruit total weight is 400 gr of which 60 g is of peel wastes. In order to reduce such pineapple peel wastes (PPW), processing to a valuable product using an environmentally friendly technique is indispensable. PPW contained phenolic compound, ferulic acid, and vitamin A and C as antioxidant. This study aimed to PPW using ethanol and water as well as to analyze its chemical properties. Both dried and fresh PPW were extracted using mixtures of ethanol and water with various concentrations ranging from 15 to 95% (v/v) at room temperature for 24 h. The chemical properties, such as antioxidant activity, total phenolic content (Gallic acid equivalent/GAE), and total sugar content were determined. The results showed that the range of Inhibition Concentration (IC)50 value as antioxidant activity of extracts from dried and fresh PPW were in the range of 0.8±0.05 to 1.3±0.09 mg.mL-1 and 0.25±0.01 to 0.59±0.01 mg.mL-1, respectively, with the highest antioxidant activity was in water extract. The highest of total phenolic content of 0.9 mg.g-1 GAE, was also found in water extract.

  14. Effects of size and thermophilic pre-hydrolysis of banana peel during anaerobic digestion, and biomethanation potential of key tropical fruit wastes.

    PubMed

    Odedina, Mary Jesuyemi; Charnnok, Boonya; Saritpongteeraka, Kanyarat; Chaiprapat, Sumate

    2017-10-01

    Methane production potential of tropical fruit wastes, namely lady-finger banana peel, rambutan waste and longan waste were compared using BMP assay and stoichiometric modified Buswell and Mueller equation. Methane yields based on volatile solid (VS) were in the order of ground banana peel, chopped banana peel, chopped longan waste, and chopped rambutan waste (330.6, 268.3, 234.6 and 193.2 mLCH 4 /gVS) that corresponded to their calculated biodegradability. In continuous operations of banana peel digestion at feed concentrations based on total solid (TS) 1-2%, mesophilic single stage digester run at 20-day hydraulic retention time (20-day HRT) failed at 2%TS, but successfully recovered at 1.5%TS. Pre-hydrolysis thermophilic reactor (4-d HRT) was placed as pre-treatment to mesophilic reactor (20-d HRT). Higher biogas (with an evolution of H 2 ) and energy yields were obtained and greater system stability was achieved over the single stage digestion, particularly at higher solid feedstock. The best performance of two stage digestion was 68.5% VS destruction and energy yield of 2510.9kJ/kgVS added at a feed concentration of 2%TS. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Isolation of bacterial cellulose nanocrystalline from pineapple peel waste: Optimization of acid concentration in the hydrolysis method

    NASA Astrophysics Data System (ADS)

    Anwar, Budiman; Rosyid, Nurul Huda; Effendi, Devi Bentia; Nandiyanto, Asep Bayu Dani; Mudzakir, Ahmad; Hidayat, Topik

    2016-02-01

    Isolation of needle-shaped bacterial cellulose nanocrystalline with a diameter of 16-64 nm, a fiber length of 258-806 nm, and a degree of crystallinity of 64% from pineapple peel waste using an acid hydrolysis process was investigated. Experimental showed that selective concentration of acid played important roles in isolating the bacterial cellulose nanocrystalline from the cellulose source. To achieve the successful isolation of bacterial cellulose nanocrystalline, various acid concentrations were tested. To confirm the effect of acid concentration on the successful isolation process, the reaction conditions were fixed at a temperature of 50°C, a hydrolysis time of 30 minutes, and a bacterial cellulose-to-acid ratio of 1:50. Pineapple peel waste was used as a model for a cellulose source because to the best of our knowledge, there is no report on the use of this raw material for producing bacterial cellulose nanocrystalline. In fact, this material can be used as an alternative for ecofriendly and cost-free cellulose sources. Therefore, understanding in how to isolate bacterial cellulose nanocrystalline from pineapple peel waste has the potential for large-scale production of inexpensive cellulose nanocrystalline.

  16. Bioethanol Production By Utilizing Cassava Peels Waste Through Enzymatic And Microbiological Hydrolysis

    NASA Astrophysics Data System (ADS)

    Witantri, R. G.; Purwoko, T.; Sunarto; Mahajoeno, E.

    2017-07-01

    Cassava peels waste contains, cellulose which is quite high at 43.626%, this is a potential candidate as a raw for bioethanol production. The purpose of this study was to determine the performance of the enzymatic hydrolysis, microbiological (Effective microbe) and fermentation in cassava peel waste is known from the results of quantitative measurement of multiple ethanol parameters (DNS Test, pH, ethanol concentration). This research was carried out in stages, the first stage is hydrolysis with completely randomized design with single factor variation of the catalyst, consisting of three levels ie cellulase enzymes, multienzyme and effective microbial EM4. The second stage is fermentation with factorial randomized block design, consisting of three groups of variations of catalyst, and has two factors: variations of fermipan levels 1, 2, 3% and the duration of fermentation, 2,4,6 days. The parameters in the test is a reducing sugar, pH and concentration of ethanol. The results showed that variation of hydrolysis treatment, fermentation time, and fermipan levels has real effect on the fermentation process. On average the highest ethanol content obtained from the treatment with multienzyme addition, with the addition of 2% fermipan levels and on the 2nd day of fermentation that is equal to 3.76%.

  17. Deficit irrigation and maturation stage influence quality and flavonoid composition of 'Valencia' orange fruit.

    PubMed

    Grilo, Filipa S; Di Stefano, Vita; Lo Bianco, Riccardo

    2017-04-01

    Effects of continuous deficit irrigation (DI) and partial rootzone drying (PRD) treatments (50% ETc) in comparison with full irrigation (CI, 100% ETc) were investigated during 'Valencia' orange fruit maturation. Ultra-high-performance liquid chromatography/high-resolution mass spectrometry was used to quantify hesperidin, narirutin, tangeritin, nobiletin, didymin and neoeriocitrin in the fruit juice and peel. No significant effect of irrigation was found on yield, juice soluble solids or acidity. Juice color was not influenced by irrigation or harvest date, whereas peel color increased during maturation and was more pronounced in CI and PRD fruits. Juice acidity reached a peak in May, while soluble solids increased linearly throughout maturation. Hesperidin was the major flavanone detected during maturation, with concentrations 200-fold higher in the fruit peel than in the juice. In the peel, narirutin, didymin and neoeriocitrin decreased while hesperidin, nobiletin and tangeritin increased with maturation. Narirutin synthesis in the orange fruit was insensitive to irrigation strategy. In fruit peels, PRD and DI induced the decline of hesperidin, nobiletin and tangeritin only in June, whereas in the juice, deficit irrigation treatments induced an increase in hesperidin and didymin. These results suggest that deficit irrigation, in particular the conditions imposed with PRD, may cause a significant accumulation shift of total flavonoids from the fruit peel into the juice, with a positive impact on juice quality and nutritional value. Fruit compositional changes during maturation also suggest that late harvest can improve fruit palatability and nutritional quality under the cultural and environmental conditions of this study. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  18. Antioxidant activity of apple peels.

    PubMed

    Wolfe, Kelly; Wu, Xianzhong; Liu, Rui Hai

    2003-01-29

    Consumption of fruits and vegetables has been shown to be effective in the prevention of chronic diseases. These benefits are often attributed to the high antioxidant content of some plant foods. Apples are commonly eaten and are large contributors of phenolic compounds in European and North American diets. The peels of apples, in particular, are high in phenolics. During applesauce and canned apple manufacture, the antioxidant-rich peels of apples are discarded. To determine if a useful source of antioxidants is being wasted, the phytochemical content, antioxidant activity, and antiproliferative activity of the peels of four varieties of apples (Rome Beauty, Idared, Cortland, and Golden Delicious) commonly used in applesauce production in New York state were investigated. The values of the peels were compared to those of the flesh and flesh + peel components of the apples. Within each variety, the total phenolic and flavonoid contents were highest in the peels, followed by the flesh + peel and the flesh. Idared and Rome Beauty apple peels had the highest total phenolic contents (588.9 +/- 83.2 and 500.2 +/- 13.7 mg of gallic acid equivalents/100 g of peels, respectively). Rome Beauty and Idared peels were also highest in flavonoids (306.1 +/- 6.7 and 303.2 +/- 41.5 mg of catechin equivalents/100 g of peels, respectively). Of the four varieties, Idared apple peels had the most anthocyanins, with 26.8 +/- 6.5 mg of cyanidin 3-glucoside equivalents/100 g of peels. The peels all had significantly higher total antioxidant activities than the flesh + peel and flesh of the apple varieties examined. Idared peels had the greatest antioxidant activity (312.2 +/- 9.8 micromol of vitamin C equivalents/g of peels). Apple peels were also shown to more effectively inhibit the growth of HepG(2) human liver cancer cells than the other apple components. Rome Beauty apple peels showed the most bioactivity, inhibiting cell proliferation by 50% at the low concentration of 12.4 +/- 0

  19. Application of orange peel waste in the production of solid biofuels and biosorbents.

    PubMed

    Santos, Carolina Monteiro; Dweck, Jo; Viotto, Renata Silva; Rosa, André Henrique; de Morais, Leandro Cardoso

    2015-11-01

    This work aimed to study the potential use of pyrolyzed orange peels as solid biofuels and biosorption of heavy metals. The dry biomass and the biofuel showed moderate levels of carbon (44-62%), high levels of oxygen (30-47%), lower levels of hydrogen (3-6%), nitrogen (1-2.6%), sulfur (0.4-0.8%) and ash with a maximum of 7.8%. The activation energy was calculated using Kissinger method, involving a 3 step process: volatilization of water, biomass degradation and volatilization of the degradation products. The calorific value obtained was 19.3MJ/kg. The studies of metal biosorption based on the Langmuir model obtained the best possible data fits. The results obtained in this work indicated that the potential use of waste orange peel as a biosorbent and as a solid biofuel are feasible, this product could be used in industrial processes, favoring the world economy. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Removal of total suspended solid by natural coagulant derived from cassava peel waste

    NASA Astrophysics Data System (ADS)

    Mohd-Asharuddin, S.; Othman, N.; Mohd-Zin, N. S.; Tajarudin, H. A.

    2018-04-01

    The present study was aimed to investigate the performance of starch derived from cassava peel waste as primary coagulant and coagulant aid. Comparable study was also conducted using commercially used aluminium sulfate (alum) as primary coagulant. A series of Jar tests were performed using raw water from Sembrong Barat water treatment plant. It was observed that coagulation test using cassava peel starch (CPS) alone had unappreciable removing ability. However, it was found that combination of alum-CPS successfully achieve up to 90.48% of total suspended solid (TSS) removal under optimized working conditions (pH 9, 7.5mg/L : 100 mg/L of alum : CPS dosage, rapid mixing of 200 rpm for 1 minute; 100 rpm for 2 minutes, slow mixing of 25 rpm for 30 minutes and 30 minutes settling time). This remarks the reduction in alum dosage up to 50% compared to coagulation test using alum alone. Therefore this finding suggesting that CPS can be considered as potential source of sustainable and effective coagulant aid for water treatment especially in developing countries.

  1. Ohmic Heating Assisted Lye Peeling of Pears.

    PubMed

    Gupta, Sarvesh; Sastry, Sudhir K

    2018-05-01

    Currently, high concentrations (15% to 18%) of lye (sodium hydroxide) are used in peeling pears, constituting a wastewater handling and disposal problem for fruit processors. In this study, the effect of ohmic heating on lye peeling of pears was investigated. Pears were peeled using 0.5%, 1%, 2%, and 3% NaOH under different electric field strengths at two run times and their peeled yields were compared to that obtained at 2% and 18% NaOH with conventional heating. Results revealed that ohmic heating results in greater than 95% peeled yields and the best peel quality at much lower concentrations of lye (2% NaOH at 532 V/m and 3% NaOH at 426 and 479 V/m) than those obtained under conventional heating conditions. Treatment times of 30 and 60 s showed no significant differences. Within the studied range, the effects of increasing field strength yielded no significant additional benefits. These results confirm that the concentration of lye can be significantly lowered in the presence of ohmic heating to achieve high peeled yields and quality. Our work shows that lye concentrations can be greatly reduced while peeling pears, resulting in significant savings in use of caustic chemicals, reduced costs for effluent treatment and waste disposal. © 2018 Institute of Food Technologists®.

  2. Anaerobic digestion of pre-fermented potato peel wastes for methane production.

    PubMed

    Liang, Shaobo; McDonald, Armando G

    2015-12-01

    This study investigated the feasibility of anaerobic digestion (AD) of potato peel waste (PPW) and its lactic acid fermentation residue (PPW-FR) for methane (CH4) production. The experimental results showed that about 60-70% CH4 content was obtained. The digester using PPW-FR as feedstock exhibited better performance and produced a highest cumulative CH4 production of 273 L/kg VS fed, followed by 239 L/kg VS fed using PPW under the same conditions. However, with increasing solid loadings of PPW-FR feedstock from 6.4% to 9.1%, the CH4 production was inhibited. The generation, accumulation, and degradation of volatile fatty acids (VFAs) in digesters were also investigated in this research. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Natural wrapping paper from banana (Musa paradisiaca Linn) peel waste with additive essential oils

    NASA Astrophysics Data System (ADS)

    Widiastuti Agustina, E. S.; Elfi Susanti, V. H.

    2018-05-01

    The research aimed to produce natural wrapping paper from banana (Musa Paradisiaca Linn.) peel waste with additive essentials oils. The method used in this research was alkalization. The delignification process is done with the use of NaOH 4% at the temperature of 100°C for 1.5 hours. Additive materials in the form of essential oils are added as a preservative and aroma agent, namely cinnamon oil, lemon oil, clove oil and lime oil respectively 2% and 3%. Chemical and physical properties of the produced papers are tested included water content (dry-oven method SNI ISO 287:2010), pH (SNI ISO 6588-1.2010), grammage (SNI ISO 536:2010) and brightness (SNI ISO 2470:2010). Testing results of each paper were compared with commercial wrapping paper. The result shows that the natural paper from banana peel waste with additive essential oil meets the standard of ISO 6519:2016 about Basic Paper for Laminated Plastic Wrapping Paper within the parameter of pH and water content. The paper produced also meet the standard of ISO 8218:2015 about Food Paper and Cardboard within the grammage parameter (high-grade grammage), except the paper with 2% lemon oil. The paper which is closest to the characteristic of commercial wrapping paper is the paper with the additive of 2% cinnamon oil, with pH of 6.95, the water content of 7.14%, grammage of 347.6 gram/m2 and the brightness level of 24.68%.

  4. Occurrence of methylmercury in Lake Valencia, Venezuela

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jaffe, R.; Cai, Y.; West-Thomas, J.

    1997-12-31

    The presence of mercury in the environment has received renewed attention during recent years. This is in part due to the known human health and ecological effects of the highly toxic organomercury compounds, and to the fact that novel and improved analytical techniques such as atomic fluorescence spectroscopy (AFS) and capillary chromatography with AFS detection, have enhanced significantly the detection of trace amounts of mercury and organo mercurials in environmental samples. Such techniques have allowed for a better understanding of the biogeochemical cycle of mercury in the aquatic environment. This paper reports on the presence of methylmercury in the watermore » column and sediments of a hyper-eutrophic lake. Lake Valencia is a freshwater lake located in North-Central Venezuela`s Aragua Valley. The lake`s surface area covers approximately 350 km{sup 2}, with a mean depth of 19 m and a maximum depth of 41 m. Due to the discharge of waste waters from the cities of Maracay and Valencia, as well as from other smaller villages and agricultural areas in its watershed, Lake Valencia has become hyper-eutrophic. The population of phytoplankton, particularly of blue-green algae, has increased dramatically during the last two decades resulting in anoxic conditions in the lower part of the water column during most of the year. In addition, concentrations of anthropogenic chemicals, including heavy metals, have increased in the Lake during the last four decades. 15 refs., 2 figs.« less

  5. From waste to high-value product: Jackfruit peel derived pectin/apatite bionanocomposites for bone healing applications.

    PubMed

    Govindaraj, Dharman; Rajan, Mariappan; Hatamleh, Ashraf A; Munusamy, Murugan A

    2018-01-01

    Public requirements encouraged by the current asset framework drive industry to expand its general effectiveness by enhancing existing procedures or finding new uses for waste. Thus, the aim of this study was the isolation, fabrication, and characterization of pectin derived from jackfruit (Artocarpus heterophyllus) peels and the generation of hybrid of pectin (P)/apatite (HA) (P/HA) bionanocomposites. In this process, the natural pectin polymer derived from the peel of jackfruits was used in different concentrations for the fabrication of HA bionanocomposites. Characterization of the isolated pectin and bionanocomposites samples was performed with 1 H NMR and 13 C NMR, FTIR, XRD, SEM-EDX, and HR-TEM. Cytocompatibility, ALP, fibroblast stem cells, anti-inflammatory and cell adhesion testing of the fabricated bionanocomposites was showed good biocompatibility. Our results signify that the fabricated bionanocomposites might be applicable as bone graft materials. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Ultrasound assisted extraction of pectin from waste Artocarpus heterophyllus fruit peel.

    PubMed

    Moorthy, I Ganesh; Maran, J Prakash; Ilakya, S; Anitha, S L; Sabarima, S Pooja; Priya, B

    2017-01-01

    Four factors three level face centered central composite response surface design was employed in this study to investigate and optimize the effect of process variables (liquid-solid (LS) ratio (10:1-20:1ml/g), pH (1-2), sonication time (15-30min) and extraction temperature (50-70°C)) on the maximum extraction yield of pectin from waste Artocarpus heterophyllus (Jackfruit) peel by ultrasound assisted extraction method. Numerical optimization method was adapted in this study and the following optimal condition was obtained as follows: Liquid-solid ratio of 15:1ml/g, pH of 1.6, sonication time of 24min and temperature of 60°C. The optimal condition was validated through experiments and the observed value was interrelated with predicted value. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Swarm motility inhibitory and antioxidant activities of pomegranate peel processed under three drying conditions.

    PubMed

    John, K M Maria; Bhagwat, Arvind A; Luthria, Devanand L

    2017-11-15

    During processing of ready-to-eat fresh fruits, large amounts of peel and seeds are discarded as waste. Pomegranate (Punicagranatum) peels contain high amounts of bioactive compounds which inhibit migration of Salmonella on wet surfaces. The metabolic distribution of bioactives in pomegranate peel, inner membrane, and edible aril portion was investigated under three different drying conditions along with the anti-swarming activity against Citrobacter rodentium. Based on the multivariate analysis, 29 metabolites discriminated the pomegranate peel, inner membrane, and edible aril portion, as well as the three different drying methods. Punicalagins (∼38.6-50.3mg/g) were detected in higher quantities in all fractions as compared to ellagic acid (∼0.1-3.2mg/g) and punicalins (∼0-2.4mg/g). The bioactivity (antioxidant, anti-swarming) and phenolics content was significantly higher in peels than the edible aril portion. Natural anti-swarming agents from food waste may have promising potential for controlling food borne pathogens. Published by Elsevier Ltd.

  8. Pre-Harvest Dropped Kinnow ( Citrus reticulata Blanco) Waste Management through the Extraction of Naringin and Pectin from their Peels using Indigenous Resin

    NASA Astrophysics Data System (ADS)

    Laxmi Deepak Bhatlu, M.; Katiyar, Prashant; Singh, Satya Vir; Verma, Ashok Kumar

    2016-09-01

    About 10-20 % kinnow fruits are dropped in preharvest stage which are waste and are problem to farmer as these create nuisance by rotting and insect rearing ground. The peels of these dropped fruits as well as peels from kinnow processing may be good source of naringin and pectin. Naringin is used in pharmaseutics while pectin is used in food industry. For recovery of naringin and pectn, peels of preharvest dropped kinnow fruits were boiled in water. The extract was passed through macroporus polymeric adsorbent resin Indion PA 800, naringin was adsorbed on it. The adsorbed naringin was desorbed with ethanol. This solution was passed through membrane filter and filtrate was evaporated to obtain naringin. The extract remaining after adsorption of naringin was used to recover pectin using acid extraction method. The recovery of naringin and pectin was about 52 and 58 % respectively. The naringin finally obtained had 91-93 % purity.

  9. Comparison of carotenoid accumulation and biosynthetic gene expression between Valencia and Rohde Red Valencia sweet oranges

    USDA-ARS?s Scientific Manuscript database

    Carotenoid accumulation and biosynthetic gene expression levels during fruit maturation were compared between ordinary Valencia (VAL) and its more deeply colored mutant Rohde Red Valencia orange (RRV). The two cultivars exhibited different carotenoid profiles and regulatory mechanisms in flavedo and...

  10. Hydrolysis of alkaline pretreated banana peel

    NASA Astrophysics Data System (ADS)

    Fatmawati, A.; Gunawan, K. Y.; Hadiwijaya, F. A.

    2017-11-01

    Banana peel is one of food wastes that are rich in carbohydrate. This shows its potential as fermentation substrate including bio-ethanol. This paper presented banana peel alkaline pretreatment and enzymatic hydrolysis. The pretreatment was intended to prepare banana peel in order to increase hydrolysis performance. The alkaline pretreatment used 10, 20, and 30% w/v NaOH solution and was done at 60, 70 and 80°C for 1 hour. The hydrolysis reaction was conducted using two commercial cellulose enzymes. The reaction time was varied for 3, 5, and 7 days. The best condition for pretreatment process was one conducted using 30% NaOH solution and at 80°C. This condition resulted in cellulose content of 90.27% and acid insoluble lignin content of 2.88%. Seven-day hydrolysis time had exhibited the highest reducing sugar concentration, which was7.2869 g/L.

  11. The Utilization of Banana Peel in the Fermentation Liquid in Food Waste Composting

    NASA Astrophysics Data System (ADS)

    Kadir, A. A.; Rahman, N. A.; Azhari, N. W.

    2016-07-01

    Municipal solid waste in Malaysia contains a high amount of organic matters, particularly food waste. Food waste represents almost 60% from the total municipal solid waste disposed in the landfill. Food waste can be converted into useful materials such as compost. However, source separation of food waste for recycling is not commonly practiced in Malaysia due to various constraints. These constraints include low awareness among the waste generators and low demand of the products produced from the food waste such as composts. Composting is one of the alternatives that can be used in food waste disposal from Makanan Ringan Mas. The aim of the study is to convert food waste generated from Makanan Ringan Mas which is a medium sale industry located at Parit Kuari Darat, Batu Pahat by using composting method. The parameters which include temperature, pH value, NPK (Nitrogen, Phosphorus, Potassium) values has been examined. Banana peel is being used as the fermentation liquid whilst soil and coconut husk were used as the composting medium. Based on the results during the composting process, most of the pH value in each reactor is above 5 and approximately at neutral. This shown that the microbial respiration in the well controlled composting reactor was inhibited and had approached the mature phase. On the other hand, during the period of composting, the overall temperature range from 25 °C to 47 °C which shown the active phase for composting will occoured. As for NPK content Nitrogen value range is 35325 mg/L to 78775 mg/L, Phosphorus, 195.83 mg/L to 471 mg/L and potassium is 422.3 mg/L to 2046 mg/L which is sufficient to use for agricultural purpose. The comparison was made with available organic compost in the market and only showed slightly difference. Nevertheless, in comparison with common fertilizer, the NPK value of organic compost are considerably very low.

  12. Biosorption of cationic dyes on breadfruit ( Artocarpus altilis) peel and core

    NASA Astrophysics Data System (ADS)

    Priyantha, Namal; Lim, Linda B. L.; Tennakoon, D. T. B.; Liaw, Elaine T. Z.; Ing, Chieng Hei; Liyandeniya, Anushka B.

    2018-03-01

    The purpose of this research is to investigate biosorption characteristics of two cationic dyes, methylene blue (MB) and methyl violet 2B (MV), on breadfruit ( Artocarpus altilis) peel and core. Characterization of breadfruit waste was conducted using surface titrations, thermogravimetry, and Fourier transform infrared spectroscopy. The extent of interaction between dyes and each biosorbent was monitored by absorbance measurements, which was then used in isotherm, thermodynamics, and kinetics analysis. Biosorption of MB and MV on breadfruit peel and core reaches equilibrium in 150-180 min. All four systems under investigation (MB-breadfruit peel, MB-breadfruit core, MV-breadfruit peel, and MV-breadfruit core) show similar extent of dye removal of about 80% under the conditions employed. Biosorption of both dyes on both biosorbents follow the Langmuir adsorption isotherm model at the ambient pH, at which the breadfruit surface bears a negative charge. Kinetics of biosorption of MB on breadfruit waste is so fast that it is not possible to determine the order of adsorption kinetics at the concentration level employed. The rate of biosorption of MV on breadfruit waste is smaller and follows pseudo second order kinetics with rate constants of 153.5 and 31.7 g mmol-1 min-1 for peel and core, respectively. Thermodynamics studies conducted for each biosorption system provide negative Δ G Θ, Δ H Θ and Δ S Θ values with the maximum biosorption for MB at the ambient temperature of 24 °C, while that for MV is obtained between 40 and 50 °C. All four biosorption systems show spontaneity and exothermic behaviour to varying degrees.

  13. Analysis of microbial community variation during the mixed culture fermentation of agricultural peel wastes to produce lactic acid.

    PubMed

    Liang, Shaobo; Gliniewicz, Karol; Gerritsen, Alida T; McDonald, Armando G

    2016-05-01

    Mixed cultures fermentation can be used to convert organic wastes into various chemicals and fuels. This study examined the fermentation performance of four batch reactors fed with different agricultural (orange, banana, and potato (mechanical and steam)) peel wastes using mixed cultures, and monitored the interval variation of reactor microbial communities with 16S rRNA genes using Illumina sequencing. All four reactors produced similar chemical profile with lactic acid (LA) as dominant compound. Acetic acid and ethanol were also observed with small fractions. The Illumina sequencing results revealed the diversity of microbial community decreased during fermentation and a community of largely lactic acid producing bacteria dominated by species of Lactobacillus developed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Development of environmental friendly lost circulation material from banana peel

    NASA Astrophysics Data System (ADS)

    Sauki, Arina; Hasan, Nur â.€˜Izzati; Naimi, Fardelen Binti Md; Othman, Nur Hidayati

    2017-12-01

    Loss of expensive mud could lead to major financial problem in executing a drilling project and is one of the biggest problems that need to be tackled during drilling. Synthetic Based Mud (SBM) is the most stable state of the art drilling mud used in current drilling technologies. However, the problem with lost circulation is still inevitable. The focus of this project is to develop a new potential waste material from banana peel in order to combat lost circulation in SBM. Standard industrial Lost Circulation Material (LCM) is used to compare the performance of banana peel as LCM in SBM. The effects of different sizing of banana peels (600 micron, 300 micron and 100 micron) were studied on the rheological and filtration properties of SBM and the bridging performance of banana peel as LCM additive. The tests were conducted using viscometer, HTHP filter press and sand bed tester. Thermal analysis of banana peel was also studied using TGA. According to the results obtained, 300 and 100 micron size of banana peel LCM exhibited an improved bridging performance by 65% as compared to industrial LCM. However, banana peel LCM with the size of 600 micron failed to act as LCM due to the total invasion of mud into the sand bed.

  15. Fabrication of spherical biochar by a two-step thermal process from waste potato peel.

    PubMed

    Yang, Xiao; Kwon, Eilhann E; Dou, Xiaomin; Zhang, Ming; Kim, Ki-Hyun; Tsang, Daniel C W; Ok, Yong Sik

    2018-06-01

    The aim of this study was to develop a new approach for the preparation of spherical biochar (SBC) by employing a two-step thermal technology to potato peel waste (PPW). Potato starch (PS), as a carbon-rich material with microscale spherical shape, was separated from PPW as a precursor to synthesizing SBC. The synthesis process comprised (1) pre-oxidization (preheating under air) of PS at 220 °C and (2) subsequent pyrolysis of the pretreated sample at 700 °C. Results showed that the produced SBC successfully retained the original PS morphology and that pre-oxidization was the key for its shape maintenance, as it reduced surface tension and enhanced structural stability. The SBC possessed excellent chemical inertness (high aromaticity) and uniform particle size (10-30 μm). Zero-cost waste material with a facile and easy-to-control process allows the method to be readily scalable for industrialization, while offering a new perspective on the full use of PPW. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Peeling-angle dependence of the stick-slip instability during adhesive tape peeling.

    PubMed

    Dalbe, Marie-Julie; Santucci, Stéphane; Vanel, Loïc; Cortet, Pierre-Philippe

    2014-12-28

    The influence of peeling angle on the dynamics observed during the stick-slip peeling of an adhesive tape has been investigated. This study relies on a new experimental setup for peeling at a constant driving velocity while keeping constant the peeling angle and peeled tape length. The thresholds of the instability are shown to be associated with a subcritical bifurcation and bistability of the system. The velocity onset of the instability is moreover revealed to strongly depend on the peeling angle. This could be the consequence of peeling angle dependance of either the fracture energy of the adhesive-substrate joint or the effective stiffness at play between the peeling front and the point at which the peeling is enforced. The shape of the peeling front velocity fluctuations is finally shown to progressively change from typical stick-slip relaxation oscillations to nearly sinusoidal oscillations as the peeling angle is increased. We suggest that this transition might be controlled by inertial effects possibly associated with the propagation of the peeling force fluctuations through elongation waves in the peeled tape.

  17. Activated carbon electrode from banana-peel waste for supercapacitor applications

    NASA Astrophysics Data System (ADS)

    Taer, E.; Taslim, R.; Aini, Z.; Hartati, S. D.; Mustika, W. S.

    2017-01-01

    Seven types of activated carbon electrode (ACM) have been produced from the banana peel waste for supercapacitor application. The difference type of the electrode was synthesized by the various conditions of carbonization and activation. The production of the ACM was begun by the milling process and molded by a solution casting technique. The next step was followed by drying, carbonization and activation process. Physical properties of the ACM were studied by the N2 gas absorption-desorption method to characterize the specific surface area of the sample. On the other side, the electrochemical properties such as specific capacitance (Csp), specific energy (E) and specific power (P) were resulted by calculating the current (I) and voltage (V) data from the cyclic voltammetry testing. Based on the data obtained the surface area of the ACM has a significant relationship with the electrochemical properties. The specific surface area (SBET), Csp, E and P were found the maximum value as high as 581m2 / g, 68 F/g, 0.75 Wh/kg and 31 W/kg, respectively. Further more, this paper were also analyzed the relationship between electrochemical properties of supercapacitor with the degree of crystallization of the ACM.

  18. Chemical Peels

    MedlinePlus

    ... and Post-inflammatory hyperpigmentation - after Tazortene, hydroquinone, and salicylic acid chemical peels Photo courtesy of of P. Grimes ... after treatment with hydroquinone, TCA chemical peel, and salicylic acid chemical peel. Photo courtesy of of P. Grimes ...

  19. Anaerobic digestion of orange peel in a semi-continuous pilot plant: An environmentally sound way of citrus waste management in agro-ecosystems.

    PubMed

    Zema, Demetrio A; Fòlino, Adele; Zappia, Giovanni; Calabrò, Paolo S; Tamburino, Vincenzo; Zimbone, Santo Marcello

    2018-07-15

    The management of residues of citrus processing involves economic and environmental problems. In particular, the uncontrolled disposal of citrus processing waste near production sites can have heavy impacts on air, soil, surface water bodies and groundwater. Anaerobic digestion has been proposed as a viable alternative for citrus waste valorisation, if some problems, linked to the biochemical processes, are overcome. Although many experimental tests have studied the inhibitory effects of the high essential oil content of orange peel on biomethanisation processes, fewer experiences have been carried out in continuous or semi-continuous pilot digesters, more similar to the full-scale biogas plants, using real orange peel. This study has evaluated the methane production through anaerobic digestion of industrial orange peel using a pilot plant (84L) with semi-continuous feeding at increasing Organic Loading Rates (OLR) and essential oil (EO) supply rates (EOsr) until the complete process inhibition. Under mesophilic conditions, the highest daily specific methane yield was achieved at OLR of 1.0g TVS L -1 d -1 and EOsr of 47.6mgL -1 d -1 . Partial inhibition of the anaerobic digestion was detected at OLR and EOsr of 1.98g TVS L -1 d -1 and 88.1mgL -1 d -1 , respectively and the process irreversibly stopped when OLR and EOsr reached 2.5g TVS L -1 d -1 and 111.2mgL -1 d -1 , respectively. Under thermophilic conditions, the cumulative methane production (0.12Lg TVS -1 ) was about 25% of that under mesophilic conditions (0.46Lg TVS -1 ). The thermophilic digestion was completely inhibited at lower OLR (1.98g TVS L -1 d -1 ) and EOsr (88.1mgL -1 d -1 ) compared to mesophilic conditions. This study confirmed the suitability of anaerobic digestion of orange peel for biomethane production (provided that the right management of the process is set), in view of an environmentally sound way of agricultural residues management in agro-ecosystems. Copyright © 2018 Elsevier B.V. All

  20. Lactic acid production with undefined mixed culture fermentation of potato peel waste.

    PubMed

    Liang, Shaobo; McDonald, Armando G; Coats, Erik R

    2014-11-01

    Potato peel waste (PPW) as zero value byproduct generated from food processing plant contains a large quantity of starch, non-starch polysaccharide, lignin, protein, and lipid. PPW as one promising carbon source can be managed and utilized to value added bioproducts through a simple fermentation process using undefined mixed cultures inoculated from wastewater treatment plant sludge. A series of non-pH controlled batch fermentations under different conditions such as pretreatment process, enzymatic hydrolysis, temperature, and solids loading were studied. Lactic acid (LA) was the major product, followed by acetic acid (AA) and ethanol under fermentation conditions without the presence of added hydrolytic enzymes. The maximum yields of LA, AA, and ethanol were respectively, 0.22 g g(-1), 0.06 g g(-1), and 0.05 g g(-1). The highest LA concentration of 14.7 g L(-1) was obtained from a bioreactor with initial solids loading of 60 g L(-1) at 35°C. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Green way genesis of silver nanoparticles using multiple fruit peels waste and its antimicrobial, anti-oxidant and anti-tumor cell line studies

    NASA Astrophysics Data System (ADS)

    Naganathan, Kiruthika; Thirunavukkarasu, Somanathan

    2017-04-01

    Green synthesis of silver nanoparticles (SNP) opens a new path to kill and prevent various infectious diseases and also tumor. In this study, we have synthesized silver nanoparticles using multiple fruit peel waste (pomegranate, orange, banana and apple (POBA)). The primarily nanoparticles formation has been confirmed by the color change. The synthesized SNP were analyzed by various physicochemical techniques such as UV- Visible spectroscopy, x-ray diffraction (XRD), fourier transform infra red (FT-IR) spectroscopy and transmission electron microscope (TEM). The formation of SNP was confirmed by its absorbance peak observed at 430 nm in UV-Visible spectrum. Further, the obtained SNP were identified by XRD and TEM, respectively to know the crystalline nature and size and shape of the particles. The activities of SNP were checked with human pathogens (Salmonella, E.coli and Pseudomonas), plant pathogen (Fusarium) and marine pathogen (Aeromonas hydrophila) and also studied the scavenging effect and anticancer properties against MCF-7 cell lines. This studies proves that the SNP prepared from fruit waste peel extract approach appears extremely fast, cost efficient, eco-friendly and alternative for conventional methods of SNP synthesis to promote the usage of these nanoparticles in medicinal application.

  2. Juice volatile composition differences between Valencia orange and its mutant Rohde Red Valencia are associated with carotenoid profile differences

    USDA-ARS?s Scientific Manuscript database

    A targeted approach using HS-SPME-GC–MS was performed to investigate volatile compounds of ordinary Valencia (VAL) and its more deeply colored mutant Rohde Red Valencia orange (RRV) at different developmental stages. Fifty-six volatile components classified into six chemical groups were quantified. ...

  3. Pomegranate peel and peel extracts: chemistry and food features.

    PubMed

    Akhtar, Saeed; Ismail, Tariq; Fraternale, Daniele; Sestili, Piero

    2015-05-01

    The present review focuses on the nutritional, functional and anti-infective properties of pomegranate (Punica granatum L.) peel (PoP) and peel extract (PoPx) and on their applications as food additives, functional food ingredients or biologically active components in nutraceutical preparations. Due to their well-known ethnomedical relevance and chemical features, the biomolecules available in PoP and PoPx have been proposed, for instance, as substitutes of synthetic food additives, as nutraceuticals and chemopreventive agents. However, because of their astringency and anti-nutritional properties, PoP and PoPx are not yet considered as ingredients of choice in food systems. Indeed, considering the prospects related to both their health promoting activity and chemical features, the nutritional and nutraceutical potential of PoP and PoPx seems to be still underestimated. The present review meticulously covers the wide range of actual and possible applications (food preservatives, stabilizers, supplements, prebiotics and quality enhancers) of PoP and PoPx components in various food products. Given the overall properties of PoP and PoPx, further investigations in toxicological and sensory aspects of PoP and PoPx should be encouraged to fully exploit the health promoting and technical/economic potential of these waste materials as food supplements. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Succinic acid production from orange peel and wheat straw by batch fermentations of Fibrobacter succinogenes S85.

    PubMed

    Li, Qiang; Siles, Jose A; Thompson, Ian P

    2010-10-01

    Succinic acid is a platform molecule that has recently generated considerable interests. Production of succinate from waste orange peel and wheat straw by consolidated bioprocessing that combines cellulose hydrolysis and sugar fermentation, using a cellulolytic bacterium, Fibrobacter succinogenes S85, was studied. Orange peel contains D-limonene, which is a well-known antibacterial agent. Its effects on batch cultures of F. succinogenes S85 were examined. The minimal concentrations of limonene found to inhibit succinate and acetate generation and bacterial growth were 0.01%, 0.1%, and 0.06% (v/v), respectively. Both pre-treated orange peel by steam distillation to remove D: -limonene and intact wheat straw were used as feedstocks. Increasing the substrate concentrations of both feedstocks, from 5 to 60 g/L, elevated succinate concentration and productivity but lowered the yield. In addition, pre-treated orange peel generated greater succinate productivities than wheat straw but had similar resultant titres. The greatest succinate titres were 1.9 and 2.0 g/L for pre-treated orange peel and wheat straw, respectively. This work demonstrated that agricultural waste such as wheat straw and orange peel can be biotransformed to succinic acid by a one-step consolidated bioprocessing. Measures to increase fermentation efficiency are also discussed.

  5. Chemical composition and in vitro gas production of silage from guinea grass, cassava peel and cashew apple waste at different periods of ensilage.

    PubMed

    Dele, P A; Jolaosho, A O; Arigbede, O M; Ojo, V O A; Amole, T A; Okukenu, O A; Akinyemi, B T

    2013-12-01

    A study was carried out to determine the quality of silage produced from guinea grass, cassava peel and cashew apple waste at different ensiling periods. The materials were mixed into nine different proportions and ensiled for 30, 60 and 90 days making twenty-seven (27) treatments with each replicated three times. At the expiration of ensiling duration, the jars were opened, the contents were mixed, oven-dried and the proximate composition and fibre fractions were determined. The results showed that there were significant (p < 0.05) reduction in the Dry Matter (DM), Crude Protein (CP) and Neutral Detergent Fibre (NDF) with increase in ensiling duration while the Non Fibre Carbohydrate (NFC) increased with increased ensiling duration. The highest CP content (14.44%) was obtained in 25% Guinea Grass (GG)+25% cassava peel (CAP)+50% Cashew Apple Waste (CAW) which was not significantly (p > 0.05) different from 100% CAW. The NDF varied (p < 0.05) from 44.21 in 75% CAP+25% CAW silage to 60.31 in 100% GG. The reduction in the CP and NDF of the silage is still within the range required for growth and maintenance in ruminant animals.

  6. Adsorption of heavy metals from water using banana and orange peels.

    PubMed

    Annadural, G; Juang, R S; Lee, D J

    2003-01-01

    Liquid-phase adsorption removal of Cu2+, Co2+, Ni2+, Zn2+, and Pb2+ in the concentration range of 5-25 mg/L using low-cost banana and orange peel wastes was examined at 30 degrees C. Under comparable conditions, the amount of adsorption decreased in the order Pb2+ > Ni2+ > Zn2+ > Cu2+ > Co2+ for both adsorbents. The adsorption isotherms could be better described by the Freundlich equation. The amount of adsorption increased with increasing pH and reached a plateau at pH > 7, which was confirmed by the variations of zeta potentials. The application potential of such cellulose-based wastes for metal removal (up to 7.97 mg Pb2+ per gram of banana peel at pH 5.5) at trace levels appeared to be promising.

  7. Self-peeling of impacting droplets

    NASA Astrophysics Data System (ADS)

    de Ruiter, Jolet; Soto, Dan; Varanasi, Kripa K.

    2018-01-01

    Whether an impacting droplet sticks or not to a solid surface has been conventionally controlled by functionalizing the target surface or by using additives in the drop. Here we report on an unexpected self-peeling phenomenon that can happen even on smooth untreated surfaces by taking advantage of the solidification of the impacting drop and the thermal properties of the substrate. We control this phenomenon by tuning the coupling of the short-timescale fluid dynamics--leading to interfacial defects upon local freezing--and the longer-timescale thermo-mechanical stresses--leading to global deformation. We establish a regime map that predicts whether a molten metal drop impacting onto a colder substrate will bounce, stick or self-peel. In many applications, avoiding adhesion of impacting droplets around designated target surfaces can be as crucial as bonding onto them to minimize waste or cleaning. These insights have broad applicability in processes ranging from thermal spraying and additive manufacturing to extreme ultraviolet lithography.

  8. The antioxidant activitives of mango peel among different cultivars

    NASA Astrophysics Data System (ADS)

    Liu, Yu-Ge; Zhang, Xiu-Mei; Ma, Fei-Yue; Fu, Qiong

    2017-04-01

    In this paper, the contents of total phenol and total flavonoid of 8 mango cultivars were determined. Their antioxidant abilities were also evaluated by 1,1-diphenyl-2-pireyhydrazyl (DPPH) radical scavenging, trolox equivalent antioxidant capacity (TEAC) and ferric reducing antioxidant power (FRAP). Correlations between total phenol, total flavonoid and FRAP as well as TEAC were also analyzed. Results showed that mango peels were rich in natural antioxidant compounds the antioxidant abilities were different among different cultivars. The correlations between total phenol, total flavonoid and FRAP indicated phenolics represent a major part of antioxidant capacity in mango peels. This was also useful in the utilization of mango processing waste.

  9. Chemical peels.

    PubMed

    Jackson, Adrianna

    2014-02-01

    Chemical peels are a method of resurfacing with a long-standing history of safety in the treatment of various skin conditions. This article reviews the classification of different chemical agents based on their depth of injury. The level of injury facilitates cell turnover, epidermal thickening, skin lightening, and new collagen formation. Preprocedural, periprocedural, and postprocedural skin care are briefly discussed. To select the appropriate chemical peel, the provider should evaluate the patient's expectations, medical history, skin type, and possible complications to determine the best chemical peel to achieve the desired results. Patients with Fitzpatrick skin types IV to VI have increased risk of dyspigmentation, hypertrophic, and keloid scarring. These individuals respond well to superficial and medium-depth chemical peels. Advances in the use of combination peels allow greater options for skin rejuvenation with less risk of complications. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  10. Light pollution in Valencia: public awareness

    NASA Astrophysics Data System (ADS)

    Marco, E.; Morales-Rubio, A.

    2015-05-01

    Light pollution is caused by the direct and indirect light emission into the atmosphere from artificial night sources. The most decisive effect is the increasing of the luminance of the sky preventing stargazing. The fundamental actor for solving the problem is public awareness. Therefore, in accordance with authorities of the Valencian natural parks, municipalities and high schools, we have held a series of explanatory talks to the general public on the problem of light pollution, not only about the loss of the night and its impact on Astronomy, but also about the waste of energy and its impact on nocturnal wildlife and human health. Furthermore, in order to emphasize the need to preserve dark skies, popular astronomical observations have been also performed. An informative brochure on the problem of light pollution, with real cases involving natural parks, Valencia and its metropolitan area, has been published.

  11. Microstructure characterization of onion (A.cepa) peels and thin films for dye sensitized solar cells

    NASA Astrophysics Data System (ADS)

    Abodunrin, T.; Boyo, A.; Usikalu, M.; Obafemi, L.; Oladapo, O.; Kotsedi, L.; Yenus, Z.; Maaza, M.

    2017-03-01

    A.cepa peels are obtained from mature onion bulbs. Because of the continuous need for energy, alternative avenues for producing energy are gaining importance. The motivation for this work is based on an urgent need to source energy from readily available waste materials like domestic onion peels. Dye sensitized solar cells (DSSCs) fabricated via doctor blade method and high temperature sintering from waste (onion peels) are investigated for their ability to convert solar to electrical energy. The charge carriers were revealed under phytochemical screening. Functional groups of compounds present in A.cepa peel were analyzed with Fourier transform in infrared (FTIR). The influence of different electrolyte sensitizer is observed on the DSSCs under standard air mass conditions of 1.5 AM. The microstructure properties of these A.cepa DSSCs were explored using scanning electron microscope with energy dispersive spectroscopy (SEM/EDS), x-ray diffraction and Fluorecence spectroscopy (XRF). The interfacial boundary between A.cepa dye, TiO2 framework of TiO2 and indium doped tin oxide (ITO) reveals several prominent anatase and rutile peaks. Photoelectric results, revealed dye-sensitized solar cells with a maximum power output of 126 W and incident photon to conversion energy (IPCE) of 0.13%.This work has established that A.cepa peels can be used as a source of micro-energy generation.

  12. Peeling skin syndrome.

    PubMed

    Ilknur, Turna; Demirtaşoğlu, Melda; Akarsu, Sevgi; Lebe, Banu; Güneş, Ali Tahsin; Ozkan, Sebnem

    2006-01-01

    Peeling skin syndrome is a rare disease characterized by widespread painless peeling of the skin. To date, several cases have been described with different clinical features called peeling skin syndrome. Previous reports describe two types (type A and type B) of peeling skin syndrome, both of which show generalized desquamation, sparing palms and soles. We report a 23-year old man who has been classified as neither type A nor type B, and whose history, clinical features and histopathological findings led to a diagnosis of peeling skin syndrome. In addition, the desquamation pattern in our patient was different from that of both types because our case's palms and soles were involved too.

  13. Biomethanization of citrus waste: Effect of waste characteristics and of storage on treatability and evaluation of limonene degradation.

    PubMed

    Lotito, Adriana Maria; De Sanctis, Marco; Pastore, Carlo; Di Iaconi, Claudio

    2018-06-01

    This study proposes the evaluation of the suitability of mesophilic anaerobic digestion as a simple technology for the treatment of the citrus waste produced by small-medium agro-industrial enterprises involved in the transformation of Citrus fruits. Two different stocks of citrus peel waste were used (i.e., fresh and stored citrus peel waste), to evaluate the influence of waste composition (variability in the type of processed Citrus fruits) and of storage (potentially necessary to operate the anaerobic digester continuously over the whole year due to the seasonality of the production) on anaerobic degradation treatability. A thorough characterization of the two waste types has been performed, showing that the fresh one has a higher solid and organic content, and that, in spite of the similar values of oil fraction amounts, the two stocks are significantly different in the composition of essential oils (43% of limonene and 34% of linalyl acetate in the fresh citrus waste and 20% of limonene and 74% of linalyl acetate in the stored citrus waste). Contrarily to what observed in previous studies, anaerobic digestion was successful and no reactor acidification occurred. No inhibition by limonene and linalyl acetate even at the maximum applied organic load value (i.e., 2.72 gCOD waste /gVS inoculum ) was observed in the treatment of the stored waste, with limonene and linalyl acetate concentrations of 104 mg/l and 385 mg/l, respectively. On the contrary, some inhibition was detected with fresh citrus peel waste when the organic load increased from 2.21 to 2.88 gCOD waste /gVS inoculum , ascribable to limonene at initial concentration higher than 150 mg/l. A good conversion into methane was observed with fresh peel waste, up to 0.33  [Formula: see text] at the highest organic load, very close to the maximum theoretical value of 0.35 [Formula: see text] , while a lower efficiency was achieved with stored peel waste, with a reduction down to 0.24  [Formula: see

  14. Chemical Peel

    MedlinePlus

    ... chemical peel: Your doctor will use a brush, cotton ball, gauze or sponge to apply a chemical ... medium chemical peel: Your doctor will use a cotton-tipped applicator or gauze to apply a chemical ...

  15. Chemical peeling in ethnic/dark skin.

    PubMed

    Roberts, Wendy E

    2004-01-01

    Chemical peeling for skin of color arose in ancient Egypt, Mesopotamia, and other ancient cultures in and around Africa. Our current fund of medical knowledge regarding chemical peeling is a result of centuries of experience and research. The list of agents for chemical peeling is extensive. In ethnic skin, our efforts are focused on superficial and medium-depth peeling agents and techniques. Indications for chemical peeling in darker skin include acne vulgaris, postinflammatory hyperpigmentation, melasma, scarring, photodamage, and pseudofolliculitis barbae. Careful selection of patients for chemical peeling should involve not only identification of Fitzpatrick skin type, but also determining ethnicity. Different ethnicities may respond unpredictably to chemical peeling regardless of skin phenotype. Familiarity with the properties each peeling agent used is critical. New techniques discussed for chemical peeling include spot peeling for postinflammatory hyperpigmentation and combination peels for acne and photodamage. Single- or combination-agent chemical peels are shown to be efficacious and safe. In conclusion, chemical peeling is a treatment of choice for numerous pigmentary and scarring disorders arising in dark skin tones. Familiarity with new peeling agents and techniques will lead to successful outcomes.

  16. Viscous peeling with capillary suction

    NASA Astrophysics Data System (ADS)

    Peng, Gunnar; Lister, John

    2014-11-01

    If an elastic tape is stuck to a rigid substrate by a thin film of viscous fluid and then peeled off by pulling at a small angle to the horizontal, then both viscous and capillary forces affect the peeling speed (McEwan and Taylor, 1966). If there is no capillary meniscus (e.g. if the peeling is due to viscous fluid being injected under the tape), then the peeling speed is given by a Cox-Voinov-like law, and is an increasing function of the peeling angle. We show that, with a meniscus present, the effect of the capillary forces is to suck down the tape, reducing the effective peeling angle and hence the peeling speed. When surface tension dominates and the peeling speed tends to zero, the system transitions to a new state whose time-evolution can be described by a system of coupled ordinary differential equations. These asymptotic results are confirmed by numerical calculations. Similar results hold for the peeling-by-bending of elastic beams, with ``angle'' replaced by ``curvature'' (i.e. bending moment).

  17. Removal of Pb(II) and Cd(II) from water by adsorption on peels of banana.

    PubMed

    Anwar, Jamil; Shafique, Umer; Waheed-uz-Zaman; Salman, Muhammad; Dar, Amara; Anwar, Shafique

    2010-03-01

    The adsorption of lead(II) and cadmium(II) on peels of banana has been studied in batch mode using flame atomic absorption spectroscopy for metal estimation. Concerned parameters like adsorbent dose, pH, contact time and agitation speed were investigated. Langmuir, Freundlich and Temkin isotherms were employed to describe adsorption equilibrium. The maximum amounts of cadmium(II) and lead(II) adsorbed (qm), as evaluated by Langmuir isotherm, were 5.71 mg and 2.18 mg per gram of powder of banana peels, respectively. Study concluded that banana peels, a waste material, have good potential as an adsorbent to remove toxic metals like lead and cadmium from water. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

  18. Preparation using pectinase and characterization of nanofibers from orange peel waste in juice factories.

    PubMed

    Hideno, Akihiro; Abe, Kentaro; Yano, Hiroyuki

    2014-06-01

    This study reports the preparation and characterization of nanofibers consisting mainly of cellulose microfibrils from orange peel (OP), which is a significant byproduct of orange juice production. Three treatments (boiling, alkaline, and pectinase) were investigated with and without subsequent grinding treatment. It was possible to prepare the cellulose nanofibers (CNFs) using these methods, except for the boiling treatment with grinding. Interestingly, only pectinase and a mild-physical blender treatment without grinding produced nanofibers. The width of the nanofibers from OP was approximately 10 to 50 nm. The microfibril bundles of OP were considered to be thinner than those of commercial CNFs. Our data indicated that the removal of pectic polysaccharides and hemicelluloses covering the cellulose microfibrils was important for the preparation of nanofibers from OP. These nanofibers from OP using pectinase are proposed to be applicable as food materials, pharmaceuticals, and filters for the tractive characteristics of the sheet. This study demonstrates: (1) it was possible to prepare the nanofibers from orange peel using pectinase and (2) the width of the nanofibers from orange peel was approximately 10 to 50 nm. (3) Removal of polysaccharides such as pectin and hemicelluloses covering cellulose microfibrils was very important for preparation of nanofibers from OP. Considering the tractive characteristics of the sheets from nanofibers and the origin of orange peel, they are suitable for application of food materials, pharmaceuticals, and filters. © 2014 Institute of Food Technologists®

  19. Allelopathic potential of Citrus junos fruit waste from food processing industry.

    PubMed

    Kato-Noguchi, Hisashi; Tanaka, Yukitoshi

    2004-09-01

    The allelopathic potential of Citrus junos fruit waste after juice extraction was investigated. Aqueous methanol extracts of peel, inside and seeds separated from the fruit waste inhibited the growth of the roots and shoots of alfalfa (Medicago sativa L.), cress (Lepidium sativum L.), crabgrass (Digitaria sanguinalis L.), lettuce (Lactuca sativa L.), timothy (Pheleum pratense L.), and ryegrass (Lolium multiflorum Lam.). The inhibitory activity of the peel extract was greatest and followed by that of the inside and seed extracts in all bioassays. Significant reductions in the root and shoot growth were observed as the extract concentration was increased. The concentrations of abscisic acid-beta-d-glucopyranosyl ester (ABA-GE) in peel, inside and seeds separated from the C. junos fruit waste were determined, since ABA-GE was found to be one of the main growth inhibitors in C. junos fruit. The concentration was greatest in the peel, followed by the inside and seeds; there was a good correspondence between these concentrations and the inhibitory activities of the extracts. This suggests that ABA-GE may also be involved in the growth inhibitory effect of C. junos waste. These results suggested that C. junos waste may possess allelopathic potential, and the waste may be potentially useful for weed management. Copyright 2004 Elsevier Ltd.

  20. Late Quaternary environmental history of Lake Valencia, Venezuela

    USGS Publications Warehouse

    Bradbury, J. Platt; Leyden, B.; Baker, M.R.; Lewis, W.M.; Schubert, C.; Binford, M.W.; Whitehead, D.R.; Weibezahn, F.H.

    1981-01-01

    Chemical, paleontological, and mineralogical analyses of a 7.5-meter core from the middle of Lake Valencia, Venezuela, have provided information on the paleoclimatic history of this low-elevation, low-latitude site for the last 13,000 years. The data show that dry climates existed in this region from 13,000 years before present (B.P.) until about 10,000 years B.P. The Lake Valencia Basin was occupied by intermittent saline marshes at that time. About 10,000 years B.P., a permanent lake of fluctuating salinity formed and arboreal plant communities replaced the earlier dominant xeric herbaceous vegetation and marsh plants. By 8500 years B.P., Lake Valencia reached moderate to low salinities and discharged water; the modern vegetation became established at that time. After 8500 years B.P., the lake twice ceased discharging as a result of reduced watershed moisture. The second of these drying episodes is still in progress and has been aggravated by human activities in the watershed.

  1. Late quaternary environmental history of Lake Valencia, Venezuela

    USGS Publications Warehouse

    Platt, Bradbury J.; Leyden, B.; Salgado-Labouriau, M.; Lewis, W.M.; Schubert, C.; Binford, M.W.; Frey, D.G.; Whitehead, D.R.; Weibezahn, F.H.

    1981-01-01

    Chemical, paleontological, and mineralogical analyses of a 7.5-meter core from the middle of Lake Valencia, Venezuela, have provided information on the paleoclimatic history of this low-elevation, low-latitude site for the last 13,000 years. The data show that dry climates existed in this region from 13,000 years before present (B.P.) until about 10,000 years B.P. The Lake Valencia Basin was occupied by intermittent saline marshes at that time. About 10,000 years B.P., a permanent lake of fluctuating salinity formed and arboreal plant communities replaced the earlier dominant xeric herbaceous vegetation and marsh plants. By 8500 years B.P., Lake Valencia reached moderate to low salinities and discharged water; the modern vegetation became established at that time. After 8500 years B.P., the lake twice ceased discharging as a result of reduced watershed moisture. The second of these drying episodes is still in progress and has been aggravated by human activities in the watershed. Copyright ?? 1981 AAAS.

  2. Influence of extraction conditions on antioxidant properties of passion fruit (Passiflora edulis) peel.

    PubMed

    Wong, Yuh Shan; Sia, Chiaw Mei; Khoo, Hock Eng; Ang, Yee Kwang; Chang, Sui Kiat; Chang, Sui Kiat; Yim, Hip Seng

    2014-01-01

    As a by-product of tropical fruit juice industry, passion fruit peel is a valuable functional food. It is rich in antioxidants. To determine its potential antioxidant properties of passion fruit peel, this study aimed to evaluate the effect of extraction conditions on total phenolic content and antioxidant activity. The extraction conditions were selected from different percentages of ethanol (0-100%, v/v), extraction times (60-300 min), and extraction temperatures (25-60°C) that based on the optimal percentage of DPPH radical scavenging activity. The selected extraction condition was applied for further determination of total phenolic content (TPC) of the passion fruit peel extract using Folin-Ciocalteu reagent assay, while the antioxidant activities were evaluated using DPPH and ABTS radicals scavenging assays, ferric reducing antioxidant power (FRAP), and β-carotene bleaching (BCB) assay. The best extraction conditions were 40% ethanol, 60 min extraction time, and extraction temperature of 30°C. The chosen extraction conditions have contributed to the high TPC and antioxidant activity of passion fruit peel. The levels of antioxidant activity obtained from the passion fruit peel were also lower compared to BHA and α-tocopherol. Positive correlations were observed between TPC and antioxidant activities as assessed by DPPH, ABTS, FRAP, and BCB assays. As a waste of passion fruit consumption or by-product of fruit juice industry, its peel could be considered as a potential source of natural antioxidant for possible functional food and industrial applications.

  3. Local Fruit Wastes as a Potential Source of Natural Antioxidant: An Overview

    NASA Astrophysics Data System (ADS)

    Ibrahim, U. K.; Kamarrudin, N.; Suzihaque, M. U. H.; Hashib, S. Abd

    2017-06-01

    Food industry in Malaysia which used fruits as one of the raw material such as the production of fruit juices, concentrates, jams and dried fruits, the main wastes of the production are the peel and the seed of the fruit. Nowadays, people have shown the interests to study the antioxidant content in the fruit wastes. All kind of fruits are believed to contain high amount of natural antioxidant properties such as vitamins, phenol, flavonoid and carotenoid. Thus, this paper presented the work done by researcher on antioxidant activity in the peel especially on local fruit such as mango peel, watermelon rind, banana peel and mangosteen pericarp. The review shows that the peel of the fruit is a good source of antioxidant and other bioactive compounds which have many benefits especially towards human health.

  4. Modification of carotenoid levels by abscission agents and expression of carotenoid biosynthetic genes in 'valencia' sweet orange.

    PubMed

    Alferez, Fernando; Pozo, Luis V; Rouseff, Russell R; Burns, Jacqueline K

    2013-03-27

    The effect of 5-chloro-3-methyl-4-nitro-1H-pyrazole (CMNP) and ethephon on peel color, flavedo carotenoid gene expression, and carotenoid accumulation was investigated in mature 'Valencia' orange ( Citrus sinensis L. Osbeck) fruit flavedo at three maturation stages. Abscission agent application altered peel color. CMNP was more effective than ethephon in promoting green-to-red (a) and blue-to-yellow (b) color at the middle and late maturation stages and total carotenoid changes at all maturation stages. Altered flow of carotenoid precursors during maturation due to abscission agents was suggested by changes in phytoene desaturase (Pds) and ζ-carotene desaturase (Zds) gene expression. However, each abscission agent affected downstream expression differentially. Ethephon application increased β-carotene hydroxilase (β-Chx) transcript accumulation 12-fold as maturation advanced from the early to middle and late stages. CMNP markedly increased β- and ε-lycopene cyclase (Lcy) transcript accumulation 45- and 15-fold, respectively, at midmaturation. Patterns of carotenoid accumulation in flavedo were supported in part by gene expression changes. CMNP caused greater accumulation of total flavedo carotenoids at all maturation stages when compared with ethephon or controls. In general, CMNP treatment increased total red carotenoids more than ethephon or the control but decreased total yellow carotenoids at each maturation stage. In control fruit flavedo, total red carotenoids increased and yellow carotenoids decreased as maturation progressed. Trends in total red carotenoids during maturation were consistent with measured a values. Changes in carotenoid accumulation and expression patterns in flavedo suggest that regulation of carotenoid accumulation is under transcriptional, translational, and post-translational control.

  5. Purification, characterization, and prebiotic properties of pectic oligosaccharides from orange peel wastes.

    PubMed

    Gómez, Belén; Gullón, Beatriz; Remoroza, Connie; Schols, Henk A; Parajó, Juan C; Alonso, José L

    2014-10-08

    Pectic oligosaccharides (POS) were obtained by hydrothermal treatment of orange peel wastes (OPW) and purified by membrane filtration to yield a refined product containing 90 wt % of the target products. AraOS (DP 3-21), GalOS (DP 5-12), and OGalA (DP 2-12, with variable DM) were identified in POS mixtures, but long-chain products were also present. The prebiotic potential of the concentrate was assessed by in vitro fermentation using human fecal inocula. For comparative purposes, similar experiments were performed using orange pectin and commercial fructo-oligosaccharides (FOS) as substrates for fermentation. The dynamics of selected microbial populations was assessed by fluorescent in situ hybridization (FISH). Gas generation, pH, and short-chain fatty acid (SCFA) production were also measured. Under the tested conditions, all of the considered substrates were utilized by the microbiota, and fermentation resulted in increased numbers of all the bacterial groups, but the final profile of the microbial population depended on the considered carbon source. POS boosted particularly the numbers of bifidobacteria and lactobacilli, so that the ratio between the joint counts of both genera and the total cell number increased from 17% in the inocula to 27% upon fermentation. SCFA generation from POS fermentation was similar to that observed with FOS, but pectin fermentation resulted in reduced butyrate generation.

  6. Microwave-Hydrothermal Treated Grape Peel as an Efficient Biosorbent for Methylene Blue Removal

    PubMed Central

    Ma, Lin; Jiang, Chunhai; Lin, Zhenyu; Zou, Zhimin

    2018-01-01

    Biosorption using agricultural wastes has been proven as a low cost and efficient way for wastewater treatment. Herein, grape peel treated by microwave- and conventional-hydrothermal processes was used as low cost biosorbent to remove methylene blue (MB) from aqueous solutions. The adsorption parameters including the initial pH value, dosage of biosorbents, contact time, and initial MB concentration were investigated to find the optimum adsorption conditions. The biosorbent obtained by microwave-hydrothermal treatment only for 3 min at 180 °C (microwave-hydrothermal treated grape peel, MGP) showed faster kinetics and higher adsorption capability than that produced by a conventional-hydrothermal process (hydrothermal treated grape peel, HGP) with a duration time of 16 h. The maximum adsorption capability of MGP under the optimum conditions (pH = 11, a dosage of 2.50 g/L) as determined with the Langmuir model reached 215.7 mg/g, which was among the best values achieved so far on biosorbents. These results demonstrated that the grape peel treated by a quick microwave-hydrothermal process can be a very promising low cost and efficient biosorbent for organic dye removal from aqueous solutions. PMID:29385041

  7. Development of a kolanut peeling device.

    PubMed

    Kareem, I; Owolarafe, O K; Ajayi, O A

    2014-10-01

    A kolanut peeling machine was designed, constructed and evaluated for the postharvest processing of the seed. The peeling machine consists of a standing frame, peeling unit and hopper. The peeling unit consists of a special paddle, which mixes the kolanut, rubs them against one another and against the wall of the barrel and also conveys the kolanut to the outlet. The performance of the kolanut peeling machine was evaluated for its peeling efficiency at different moisture content (53.0, 57.6, 61.4 % w.b.) and speeds of operation of the machine. The result of the analysis of variance shows that the main factors and their interaction had significant effects (p < 0.05) on the peeling efficiency of the machine. The result also shows that the peeling efficiency of the machine increased as the moisture content increase and decreased with increase in machine speed. The highest efficiency of the machine was 60.3 % at a moisture content of 61.4 % w.b. and speed of 40 rpm.

  8. Charcoal from chemi-peeled hardwoods

    Treesearch

    Richard H. Fenton

    1959-01-01

    Removing bark from standing trees with sodium arsenite is an inexpensive but efficient way to produce peeled pulpwood. About 200,000 cords, principally hardwoods, are produced annually by chemi-peeling, a technique that is fast replacing old-fashioned sap-peeling as a means of debarking in the woods.

  9. Enhanced production of pectinase by Aspergillus terreus NCFT 4269.10 using banana peels as substrate.

    PubMed

    Sethi, Bijay Kumar; Nanda, Prativa Kumari; Sahoo, Santilata

    2016-06-01

    Aspergillus terreus NCFT4269.10 was implemented in solid-state (SSF) and liquid static surface fermentation (LSSF) for biosynthesis of pectinase. Amongst various substrates, like, mustard oil cake, neem oil cake, groundnut oil cake, black gram peels, green gram peels, chickling vetch peels/grass pea peels wheat bran, pearl millet residues, finger millet waste, broken rice, banana peels (BP), apple pomace (AP) and orange peels, banana peel (Musa paradisiaca L.; Family: Musaceae) was most suitable for pectinase biosynthesis (LSSF: 400 ± 21.45 Uml -1 ; SSF: 6500 ± 1116.21 Ug -1 ). Optimization of process parameters using one-variable-at-a-time method revealed that an initial medium pH of 5.0 at 30 °C and 96 h of incubation along with mannitol, urea, ammonium persulfate and isoleucine have positive influence on pectinase production. Further, K + (1 mM), Riboflavin (10 mg 100 ml -1 ) and gibberellic acid (0.025 %, w/v) supported in enhanced pectinase production. Banana peels and AP at a ratio of 9:1, moisture content of 90 % with 2 % inoculum size were suitable combinations for production of pectinase. Similarly, 96 h of soaking time with 0.1 M phosphate buffer (pH 6.5) is essential for pectinase recovery. Purification to electrophoretic homogeneity revealed 1.42 fold purification with 8.08 % yield and a molecular weight of 24.6 kDa. Scaling up of various fermentation parameters and supplementing BP as the substrate for pectinase production with better recovery could make it promising for different industrial exploitation.

  10. Katharsis of the skin: Peeling applications and agents of chemical peelings in Greek medical textbooks of Graeco-Roman antiquity.

    PubMed

    Ursin, F; Steger, F; Borelli, C

    2018-04-28

    Recipes for peelings date back to medical texts of old Egypt. The oldest medical papyri contain recipes for "improving beauty of the skin" and "removing wrinkles" by use of agents like salt and soda. The Egyptian Queen Cleopatra (69-30 BC) is said to have taken bathes in donkey's milk in order to improve the beauty of her skin. However, little is known about other agents and peeling applications in later Greek medical textbooks. We will discover new agents and describe ancient peeling applications. First, we will have to identify ancient Greek medical terms for the modern terms "peeling" and "chemical peeling". Second, based on the identified terms we will perform a systematic fulltext search for agents in original sources. Third, we will categorize the results into three peeling applications: (1) cleansing, (2) aesthetical improvement of the skin, and (3) therapy of dermatological diseases. We performed a full systematic keyword search with the identified Greek terms in databases of ancient Greek texts. Our keywords for peeling and chemical peeling are "smēxis" and "trīpsis". Our keywords for agents of peeling and chemical peeling are "smégmata", "rhýmmata", "kathartiká", and "trímmata". Diocles (4 th century BC) was the first one who mentioned "smēxis" and "trīpsis" as parts of daily cleansing routine. Criton (2 nd century AD) wrote about peeling applications, but any reference to the agents is lost. Antyllos (2 nd century AD) composed three lists of peeling applications including agents. Greek medical textbooks of Graeco-Roman antiquity report several peeling applications like cleansing, brightening, darkening, softening, and aesthetical improvement of the skin by use of peeling and chemical peeling, as well as therapy of dermatological diseases. There are 27 ancient agents for what is contemporarily called peeling and chemical peeling. We discovered more specific agents than hitherto known to research. This article is protected by copyright. All rights

  11. Effect of extraction condition on properties of pectin from banana peels and its function as fat replacer in salad cream.

    PubMed

    Maneerat, Nitjaree; Tangsuphoom, Nattapol; Nitithamyong, Anadi

    2017-02-01

    Banana peels are wasted from banana processing industry. Pectin is a soluble dietary fibre usually prepared from fruit and vegetable processing wastes. Pectin extraction from banana peels thus should be an effective way of waste utilization. This study aimed to determine the effect of extraction condition on the properties of pectin from peels of Nam Wa banana ( Musa (ABB group) 'Kluai Nam Wa') and its role as fat replacer in salad cream. Banana peel pectin (BPP) was extracted with HCl (pH 1.5) and water (pH 6.0) for 30-120 min at 90 ± 5 °C. Acid extraction yielded 7-11% pectin on a dry basis with galacturonic acid content (GalA), degree of methylation (DM), and viscosity-average molecular weight (M v ) of 42-47, 57-61%, and 17-40 kDa, respectively; while water-extracted BPP contained lower DM but higher GalA and M v . Prolonged extraction raised the pectin yield but lowered the M v of BPP and the viscosity of their solutions. Incorporation of BPP obtained from 60 min acid- and water-extraction into salad cream at 30% oil substitution level resulted in the decreases in viscosity and lightness. All reduced-fat samples were stable to cream separation during 3-weeks storage although the formula containing water-extracted BPP had larger oil droplet size and greater extent of droplet flocculation. There was no difference in sensory scores rated by 50 panelists on thickness, smoothness, and overall acceptability of the full- and reduced-fat salad creams. Therefore, Nam Wa banana peels can be an alternative source of pectin with potential application as fat replacer in food products.

  12. Degumming of ramie fiber and the production of reducing sugars from waste peels using nanoparticle supplemented pectate lyase.

    PubMed

    Mukhopadhyay, Arka; Dutta, Nalok; Chattopadhyay, Dhrubajyoti; Chakrabarti, Krishanu

    2013-06-01

    Banana, citrus and potato peels were subjected to treatment with hydroxyapatite nanoparticle (NP) supplemented purified pectate lyase (NP-PL), isolated from Bacillus megaterium AK2 to produce reducing sugar (RS). At both 50 and 90°C production of RS by NP-PL was almost twofold greater than that by untreated pectate lyase (PL) from each of the three peels. The optimal production of RS from banana and citrus peels were after 24 and 6h of incubation while it was 24 and 4h for potato peels at 50 and 90°C, respectively, on NP-PL treatment. NP-PL could degum raw, decorticated ramie fibers as well as enhance fiber tenacity and fineness. The weight loss of the fibers were 24% and 31% better (compared to PL treatment) after 24 and 48 h of processing. These findings have potential implications for the bio-ethanol, bio-fuel and textile industries. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Pyrolysis production of fruit peel biochar for potential use in treatment of palm oil mill effluent.

    PubMed

    Lam, Su Shiung; Liew, Rock Keey; Cheng, Chin Kui; Rasit, Nazaitulshila; Ooi, Chee Kuan; Ma, Nyuk Ling; Ng, Jo-Han; Lam, Wei Haur; Chong, Cheng Tung; Chase, Howard A

    2018-05-01

    Fruit peel, an abundant waste, represents a potential bio-resource to be converted into useful materials instead of being dumped in landfill sites. Palm oil mill effluent (POME) is a harmful waste that should also be treated before it can safely be released to the environment. In this study, pyrolysis of banana and orange peels was performed under different temperatures to produce biochar that was then examined as adsorbent in POME treatment. The pyrolysis generated 30.7-47.7 wt% yield of a dark biochar over a temperature ranging between 400 and 500 °C. The biochar contained no sulphur and possessed a hard texture, low volatile content (≤34 wt%), and high amounts of fixed carbon (≥72 wt%), showing durability in terms of high resistance to chemical reactions such as oxidation. The biochar showed a surface area of 105 m 2 /g and a porous structure containing mesopores, indicating its potential to provide many adsorption sites for use as an adsorbent. The use of the biochar as adsorbent to treat the POME showed a removal efficiency of up to 57% in reducing the concentration of biochemical oxygen demand (BOD), chemical oxygen demand COD, total suspended solid (TSS) and oil and grease (O&G) of POME to an acceptable level below the discharge standard. Our results indicate that pyrolysis shows promise as a technique to transform banana and orange peel into value-added biochar for use as adsorbent to treat POME. The recovery of biochar from fruit waste also shows advantage over traditional landfill approaches in disposing this waste. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. Dualities in Architectural Training: The Architecture School of Valencia (1968-1975)

    ERIC Educational Resources Information Center

    Domingo-Calabuig, Débora

    2018-01-01

    The school of Valencia was a singular case study in the architectural training in Spain towards the end of the 60s. Like in Madrid, Barcelona, and Seville, the school also participated in the bustling political and social context, but while in these schools the curriculum of 1964 was extended until 1975, in Valencia the creation of the Instituto…

  15. An evaluation of aerobic and anaerobic composting of banana peels treated with different inoculums for soil nutrient replenishment.

    PubMed

    Kalemelawa, Frank; Nishihara, Eiji; Endo, Tsuneyoshi; Ahmad, Zahoor; Yeasmin, Rumana; Tenywa, Moses M; Yamamoto, Sadahiro

    2012-12-01

    This study sought to evaluate the efficacy of aerobic and anaerobic composting of inoculated banana peels, and assess the agronomic value of banana peel-based compost. Changes in the chemical composition under aerobic and anaerobic conditions were examined for four formulations of banana peel-based wastes over a period of 12 weeks. The formulations i.e. plain banana peel (B), and a mixture with either cow dung (BC), poultry litter (BP) or earthworm (BE) were separately composted under aerobic and anaerobic conditions under laboratory conditions. Inoculation with either cow dung or poultry litter significantly facilitated mineralization in the order: BP>BC>B. The rate of decomposition was significantly faster under aerobic than in anaerobic composting conditions. The final composts contained high K (>100 g kg(-1)) and TN (>2%), indicating high potential as a source of K and N fertilizer. Copyright © 2012 Elsevier Ltd. All rights reserved.

  16. OPAC (orange peel activated carbon) derived from waste orange peel for the adsorption of chlorophenoxyacetic acid herbicides from water: Adsorption isotherm, kinetic modelling and thermodynamic studies.

    PubMed

    Pandiarajan, Aarthi; Kamaraj, Ramakrishnan; Vasudevan, Sudharshan; Vasudevan, Subramanyan

    2018-08-01

    This study presents the orange peel activated carbon (OPAC), derived from biowaste precursor (orange peel) by single step pyrolysis method and its application for the adsorption of chlorophenoxyacetic acid herbicides from the water. The OPAC exhibited the surface area of 592.471 m 2  g -1 , pore volume and pore diameter of 0.242 cc g -1 and 1.301 nm respectively. The adsorption kinetics and thermodynamic equilibrium modelling for all chlorophenoxyacetic acid herbicides were investigated. The various parametric effects such as pH and temperature were evaluated. A pseudo-second-order kinetic model was well fitted for all the herbicides. The Langmuir isotherm was obeyed for all the herbicides and the maximum Langmuir capacity of 574.71 mg g -1 was achieved. The thermodynamic studies revealed that the adsorption increases with increase in temperature. The results shows that the orange peel derived carbon (OPAC) as effective and efficient adsorbent material for the removal of chlorophenoxyacid herbicides from the water. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Physical and chemical pretreatment of lignocellulosics in pineapple (Ananus comosus) peels dried for investment

    NASA Astrophysics Data System (ADS)

    Sukkaew, Adulsman; Boonsong, Panthip; Thongpradistha, Sriubol; Intan, Maimoon

    2017-08-01

    Pineapple (Ananus comosus) Peels, once known as waste from agricultural, can be a problem when we eliminate in agriculture and industry. The current technology can help preliminarily to solve this problem. The sustainable solution to this problem is lignocellulosics pretreatments for converted saccharide as a carbon source for ethanol production. The objective of this study is the investigation of pineapple peels pretreatment to produce fermentable sugar by drying and digesting 5% sulfuric acid (H2SO4). And study of cost economic passed selection for investment. The result found that the best investment of drying was 100 °C at 11 hours for the sulphuric acid which could be easily crushed into a fine powder. Moreover, digestion of pineapple peels gave the best total sugar 252.2 g/l by 5% H2SO4 incubated for 60 minutes at room temperature. The pineapple peels were digested by 5%H2SO4 concentration by incubating for 60 minutes at room temperature, finding to be the best condition and the lowest investment. Finally, the optimisation of investment and management for lignocellulosic pretreatment will improve efficiency of strategy for economic and energy development.

  18. In Vitro Studies on Phytochemical Content, Antioxidant, Anticancer, Immunomodulatory, and Antigenotoxic Activities of Lemon, Grapefruit, and Mandarin Citrus Peels.

    PubMed

    Diab, Kawthar Ae

    2016-01-01

    In recent years, there has been considerable research on recycling of agroindustrial waste for production of bioactive compounds. The food processing industry produces large amounts of citrus peels that may be an inexpensive source of useful agents. The present work aimed to explore the phytochemical content, antioxidant, anticancer, antiproliferation, and antigenotxic activities of lemon, grapefruit, and mandarin peels. Peels were extracted using 98% ethanol and the three crude extracts were assessed for their total polyphenol content (TPC), total flavonoid content (TFC), and antioxidant activity using DPPH (1, 1diphenyl2picrylhydrazyl). Their cytotoxic and mitogenic proliferation activities were also studied in human leukemia HL60 cells and mouse splenocytes by CCK8 assay. In addition, genotoxic/ antigenotoxic activity was explored in mouse splenocytes using chromosomal aberrations (CAs) assay. Lemon peels had the highest of TPC followed by grapefruit and mandarin. In contrast, mandarin peels contained the highest of TFC followed by lemon and grapefruit peels. Among the extracts, lemon peel possessed the strongest antioxidant activity as indicated by the highest DPPH radical scavenging, the lowest effective concentration 50% (EC50= 42.97 ?g extract/ mL), and the highest Trolox equivalent antioxidant capacity (TEAC=0.157). Mandarin peel exhibited moderate cytotoxic activity (IC50 = 77.8 ?g/mL) against HL60 cells, whereas grapefruit and lemon peels were ineffective antileukemia. Further, citrus peels possessed immunostimulation activity via augmentation of proliferation of mouse splenocytes (Tlymphocytes). Citrus extracts exerted noncytotoxic, and antigenotoxic activities through remarkable reduction of CAs induced by cisplatin in mouse splenocytes for 24 h. The phytochemical constituents of the citrus peels may exert biological activities including anticancer, immunostimulation and antigenotoxic potential.

  19. Peeling mechanism of tomato under infrared heating

    USDA-ARS?s Scientific Manuscript database

    Critical behaviors of peeling tomatoes using infrared heat are thermally induced peel loosening and subsequent cracking. However, the mechanism of peel loosening and cracking due to infrared heating remains unclear. This study aimed at investigating the mechanism of peeling tomatoes under infrared h...

  20. Orange peel products can reduce Salmonella populations in ruminants.

    PubMed

    Callaway, Todd R; Carroll, Jeffery A; Arthington, John D; Edrington, Tom S; Anderson, Robin C; Rossman, Michelle L; Carr, Mandy A; Genovese, Ken J; Ricke, Steve C; Crandall, Phil; Nisbet, David J

    2011-10-01

    Salmonella can live undetected in the gut of food animals and be transmitted to humans. Animal diets can impact intestinal populations of foodborne pathogens, including Salmonella spp. Orange juice production results in a waste product, orange peel and orange pulp, which has a high nutritive value and is often included in cattle diets as a least-cost ration ingredient. Here we show that the inclusion of orange peel products reduced Salmonella Typhimurium populations in the gut of experimentally inoculated sheep. Sheep (n=24) were fed a cracked corn grain-based high grain diet that was supplemented with a 50%/50% (dry matter [DM], w/w) mixture of dried orange pellet and fresh orange peel to achieve a final concentration (DM, basis) of 0%, 10%, or 20% orange product (OP) for 10 days before inoculation with Salmonella Typhimurium. Sheep were experimentally inoculated with 10(10) colony forming units Salmonella Typhimurium, and fecal samples were collected every 24 h after inoculation. Sheep were humanely euthanized at 96 h after oral Salmonella inoculation. Populations of inoculated Salmonella Typhimurium were numerically reduced by OP treatment throughout the gastrointestinal tract, and this reduction only reached significant levels in the cecum (p<0.05) of sheep fed 10% OP diets. Apparent palatability issues decreased the consumption of OP in sheep fed 20% OP to intake levels below that of 10% OP (approximately 7% dry matter intake [DMI]/d feed refusal), thereby reducing the potential effects of OP feeding at this higher level. Our results demonstrate that orange peel and pellets are environmentally friendly and low-cost products that can be used as a pre-harvest intervention as part of an integrated pathogen reduction scheme.

  1. [Chemical peels and management of skin aging].

    PubMed

    Pelletier-Louis, M-L

    2017-10-01

    Chemical peels are an alternative and/or a complementary treatment to the surgical procedures for skin aging. The purpose of this article is to specify the procedures and the indications of the three principal types of chemical peels: alpha-hydroxy acids, trichloracetic acid, phenol-croton oil peel. The clinical examination will determine the depth of the lesions to treat and will take into consideration counter-indications and specific limits to each patient. Chemical peel is a four step procedure: pre-peel preparation, peeling itself, recovery phase and maintenance phase. The preparation is a very important phase which requires a thorough knowledge of cosmetics. This preparation can extend to any medical or surgical treatment for aging skin. Various techniques of peelings: superficial, medium, deep, combined and mosaïc peel will be detailed. These procedures require a rigorous training and a distinct learning curve. The follow up will be specified as well as the management of the possible complications. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  2. school in Valencia before the Civil War.

    PubMed

    Ferrandis, Xavier García; Vidal, Àlvar Martínez

    During the first third of the 20th century, the dental profession in Spain was disputed by several groups of healthcare professionals, including surgery practitioners and dental technicians. The most intense conflict was between dentists and stomatologists. In the case of Valencia, this struggle became apparent in the attempt to create a dental school during the first Spanish Republican period. This project was supported by the Faculty of Medicine and by the local authorities but was not implemented due to the special interests of practicing dentists and the School of Dentistry in the Central University of Madrid. The institutionalization of dentistry in Valencia was limited to the teaching of an isolated subject in the Faculty of Medicine, preventing the adoption of a university model that would have encouraged the consolidation of the dental profession in all its aspects, not solely in terms of improvements in dental care. Opposition to the project was largely based on a campaign to discredit its main promoter, Rafael Fiol Vilar (1885-1971). This Valencian doctor and dentist is virtually unknown by historians, but he had an excellent academic background and an extraordinary international projection for that time. He may have been ignored because of his exile after the Spanish Civil War and the failure of his project for the University of Valencia.

  3. [R-ALERGO. Allergy-healthy routes in Valencia].

    PubMed

    Temes Cordovez, Rafael R; Moya Fuero, Alfonso; Martí Garrido, Jaume; Perales Chordá, Carolina; Díaz Palacios, Miguel; Hernández Fernández de Rojas, Dolores

    2016-01-01

    R-ALERGO is a project developed by researchers from the Universitat Politècnica de València and the Hospital Universitario La Fe (Valencia, Spain). The main objective of the project is to create a mobile application identifying, within the city of Valencia, the most favorable routes for allergic individuals. The application is developed using nine environmental variables with a potential effect on the development of clinical manifestations in allergic individuals. The application combines the use of spatial analysis based on network technology and implemented with a geographic information system software. The first 01 version is under evaluation for a Healthy app hallmark. The next step in this project is to design a clinical validation process to test its usefulness in allergic individuals. Copyright © 2015 SESPAS. Published by Elsevier Espana. All rights reserved.

  4. Sorption kinetics and isotherm studies of a cationic dye using agricultural waste: broad bean peels.

    PubMed

    Hameed, B H; El-Khaiary, M I

    2008-06-15

    In this paper, broad bean peels (BBP), an agricultural waste, was evaluated for its ability to remove cationic dye (methylene blue) from aqueous solutions. Batch mode experiments were conducted at 30 degrees C. Equilibrium sorption isotherms and kinetics were investigated. The kinetic data obtained at different concentrations have been analyzed using pseudo-first-order, pseudo-second-order and intraparticle diffusion equations. The experimental data fitted very well the pseudo-first-order kinetic model. Analysis of the temportal change of q indicates that at the beginning of the process the overall rate of adsorption is controlled by film-diffusion, then at later stage intraparticle-diffusion controls the rate. Diffusion coefficients and times of transition from film to pore-diffusion control were estimated by piecewise linear regression. The experimental data were analyzed by the Langmuir and Freundlich models. The sorption isotherm data fitted well to Langmuir isotherm and the monolayer adsorption capacity was found to be 192.7 mg/g and the equilibrium adsorption constant Ka is 0.07145 l/mg at 30 degrees C. The results revealed that BBP was a promising sorbent for the removal of methylene blue from aqueous solutions.

  5. Rambutan peels promoted biomimetic synthesis of bioinspired zinc oxide nanochains for biomedical applications

    NASA Astrophysics Data System (ADS)

    Yuvakkumar, R.; Suresh, J.; Saravanakumar, B.; Joseph Nathanael, A.; Hong, Sun Ig; Rajendran, V.

    2015-02-01

    A naturally occurring rambutan peel waste was employed to synthesis bioinspired zinc oxide nanochains. Rambutan peels has the ability of ligating zinc ions as a natural ligation agent resulting in zinc oxide nanochains formation due to its extended polyphenolic system over incubation period. Successful formation of zinc oxide nanochains was confirmed employing transmission electron microscopy studies. About 60% and ∼40% cell viability was lost and 50% and 10% morphological change was observed in 7 and 4 days incubated ZnO treated cells compared with control. Moreover, 50% and 55% of cell death was observed at 24 and 48 h incubation with 7 days treated ZnO cells and hence alters and disturbs the growth of cancer cells and could be used for liver cancer cell treatment.

  6. Torrefaction of Durian peel and bagasse for bio-briquette as an alternative solid fuel

    NASA Astrophysics Data System (ADS)

    Haryati, S.; Rahmatullah; Putri, R. W.

    2018-03-01

    Biomass waste of durian (Durio zibethinus) peel and bagasse could be used as solid fuel by a toreffaction process. Durian peel and bagasse were washed and crushed into small sizes then dryed in order to remove water content. The treated biomass was burned at varied temperature of 200 – 350 °C and a residence time of 30 min prior to producing torrified charcoal as intermediate product. Torrified charcoal was ground into a powder blended with tapioca glue followed by casting into a cylinder to form a bio-briqquette. The bio-briquette was characterized by determining its calorific value via bomb carolimeter analysis. The key parameter of bio-briquette are calorific value and combustion rate. The result that as the burning temperature was increased the calorific value of bio-briquettes also increased. The maximum calorific value was achieved at 350°C whereas the maximum calorific value of durian (6,157 cal/gr) is higher than bagasse (6,109 cal/gr). The minimum combustion rate was attained in durian peel torrefaction at 350 °C with the rate 0.0398 g/s. The result showed that bio-briquette of durian peel and bagasse have calorific values equivalent to that of subbituminus coal in the range of 4,900 - 6,800 cal/gr.

  7. Tretinoin peel: a critical view*

    PubMed Central

    Sumita, Juliana Mayumi; Leonardi, Gislaine Ricci; Bagatin, Ediléia

    2017-01-01

    The tretinoin peel, also known as retinoic acid peel, is a superficial peeling often performed in dermatological clinics in Brazil. The first study on this was published in 2001, by Cuce et al., as a treatment option for melasma. Since then, other studies have reported its applicability with reasonable methodology, although without a consistent scientific background and consensus. Topical tretinoin is used for the treatment of various dermatoses such as acne, melasma, scars, skin aging and non-melanoma skin cancer. The identification of retinoids cellular receptors was reported in 1987, but a direct cause-effect relation has not been established. This article reviews studies evaluating the use of topical tretinoin as agent for superficial chemical peel. Most of them have shown benefits in the treatment of melasma and skin aging. A better quality methodology in the study design, considering indication and intervention is indispensable regarding concentration, vehicle and treatment regimen (interval and number of applications). Additionally, more controlled and randomized studies comparing the treatment with tretinoin cream versus its use as a peeling agent, mainly for melasma and photoaging, are necessary. PMID:29186249

  8. Tretinoin peel: a critical view.

    PubMed

    Sumita, Juliana Mayumi; Leonardi, Gislaine Ricci; Bagatin, Ediléia

    2017-01-01

    The tretinoin peel, also known as retinoic acid peel, is a superficial peeling often performed in dermatological clinics in Brazil. The first study on this was published in 2001, by Cuce et al., as a treatment option for melasma. Since then, other studies have reported its applicability with reasonable methodology, although without a consistent scientific background and consensus. Topical tretinoin is used for the treatment of various dermatoses such as acne, melasma, scars, skin aging and non-melanoma skin cancer. The identification of retinoids cellular receptors was reported in 1987, but a direct cause-effect relation has not been established. This article reviews studies evaluating the use of topical tretinoin as agent for superficial chemical peel. Most of them have shown benefits in the treatment of melasma and skin aging. A better quality methodology in the study design, considering indication and intervention is indispensable regarding concentration, vehicle and treatment regimen (interval and number of applications). Additionally, more controlled and randomized studies comparing the treatment with tretinoin cream versus its use as a peeling agent, mainly for melasma and photoaging, are necessary.

  9. Chemical peels for melasma in dark-skinned patients.

    PubMed

    Sarkar, Rashmi; Bansal, Shuchi; Garg, Vijay K

    2012-10-01

    Melasma is a common disorder of hyperpigmentation, which has a severe impact on the quality of life. Inspite of tremendous research, the treatment remains frustrating both to the patient and the treating physician. Dark skin types (Fitzpatrick types IV to VI) are especially difficult to treat owing to the increased risk of post-inflammatory hyperpigmentation (PIH). The treatment ranges from a variety of easily applied topical therapies to agents like lasers and chemical peels. Peels are a well-known modality of treatment for melasma, having shown promising results in many clinical trials. However, in darker races, the choice of the peeling agent becomes relatively limited; so, there is the need for priming agents and additional maintenance peels. Although a number of new agents have come up, there is little published evidence supporting their use in day-to -day practice. The traditional glycolic peels prove to be the best both in terms of safety as well as efficacy. Lactic acid peels being relatively inexpensive and having shown equally good results in a few studies, definitely need further experimentation. We also recommend the use of a new peeling agent, the easy phytic solution, which does not require neutralisation unlike the traditional alpha-hydroxy peels. The choice of peeling agent, the peel concentration as well as the frequency and duration of peels are all important to achieve optimum results.

  10. Chemical Peels for Melasma in Dark-Skinned Patients

    PubMed Central

    Sarkar, Rashmi; Bansal, Shuchi; Garg, Vijay K

    2012-01-01

    Melasma is a common disorder of hyperpigmentation, which has a severe impact on the quality of life. Inspite of tremendous research, the treatment remains frustrating both to the patient and the treating physician. Dark skin types (Fitzpatrick types IV to VI) are especially difficult to treat owing to the increased risk of post-inflammatory hyperpigmentation (PIH). The treatment ranges from a variety of easily applied topical therapies to agents like lasers and chemical peels. Peels are a well-known modality of treatment for melasma, having shown promising results in many clinical trials. However, in darker races, the choice of the peeling agent becomes relatively limited; so, there is the need for priming agents and additional maintenance peels. Although a number of new agents have come up, there is little published evidence supporting their use in day-to -day practice. The traditional glycolic peels prove to be the best both in terms of safety as well as efficacy. Lactic acid peels being relatively inexpensive and having shown equally good results in a few studies, definitely need further experimentation. We also recommend the use of a new peeling agent, the easy phytic solution, which does not require neutralisation unlike the traditional alpha-hydroxy peels. The choice of peeling agent, the peel concentration as well as the frequency and duration of peels are all important to achieve optimum results. PMID:23378706

  11. Integrated bioethanol and biomanure production from potato waste.

    PubMed

    Chintagunta, Anjani Devi; Jacob, Samuel; Banerjee, Rintu

    2016-03-01

    Disposal of potato processing waste and the problem of pollution associated with it is a vital issue that is being faced by the potato processing plants. The conventional peeling methods presently followed in the processing plants for removing the potato peel, also result in the loss of some portion of the mash which is rich in starch. Indiscriminate discharge of the waste causes detrimental effects in the environment, so this problem can be resolved by successful utilization of the waste for the generation of value added products. Hence, the present work focuses on integrated production of bioethanol and biomanure to utilize the waste completely leading to zero waste generation. The first part of the work describes a comparative study of ethanol production from potato peel and mash wastes by employing co-culture of Aspergillus niger and Saccharomyces cerevisiae at various incubation time (24-120 h) instead of application of enzymes. The solid state fermentation of potato peel and mash inoculated with co-culture, resulted in bioethanol production of 6.18% (v/v) and 9.30% (v/v) respectively. In the second part of the work, the residue obtained after ethanol production was inoculated with seven different microorganisms (Nostoc muscorum, Fischerella muscicola, Anabaena variabilis, Aulosira fertilissima, Cylindrospermum muscicola, Azospirillium lipoferum, Azotobacter chroococcum) and mixture of all the organisms in equal ratio for nitrogen (N), phosphorous (P) and potassium (K) enrichment. Among them, A. variabilis was found to enrich N, P and K content of the residue by nearly 7.66, 21.66 and 15 fold than that of the initial content, ultimately leading to improved N:P:K ratio of approximately 2:1:1. The application of simultaneous saccharification and fermentation (SSF) for the conversion of potato waste to ethanol and enrichment of residue obtained after ethanol production with microorganisms to be used as manure envisages environmental sustainability. Copyright

  12. Optimization of extraction parameters on the antioxidant properties of banana waste.

    PubMed

    Toh, Pui Yee; Leong, Fei Shan; Chang, Sui Kiat; Khoo, Hock Eng; Yim, Hip Seng

    2016-01-01

    Banana is grown worldwide and consumed as ripe fruit or used for culinary purposes. Peels form about 18-33% of the whole fruit and are discarded as a waste product. With a view to exploiting banana peel as a source of valuable compounds, this study was undertaken to evaluate the effect of different extraction parameters on the antioxidant activities of the industrial by-product of banana waste (peel). Influence of different extraction parameters such as types of solvent, percentages of solvent, and extraction times on total phenolic content (TPC) and antioxidant activity of mature and green peels of Pisang Abu (PA), Pisang Berangan (PB), and Pisang Mas (PM) were investigated. The best extraction parameters were initially selected based on different percentages of ethanol (0-100% v/v), extraction time (1-5 hr), and extraction temperature (25-60°C) for extraction of antioxidants in the banana peels. Total phenolic content (TPC) was evaluated using Folin-Ciocalteu reagent assay while antioxidant activities (AA) of banana peel were accessed by DPPH, ABTS, and β-carotene bleaching (BCB) assays at optimum extraction conditions. Based on different extraction solvents and percentages of solvents used, 70% and 90% of acetone had yielded the highest TPC for the mature and green PA peels, respectively; 90% of ethanol and methanol has yielded the highest TPC for the mature and green PB peels, respectively; while 90% ethanol for the mature and green PM peels. Similar extraction conditions were found for the antioxidant activities for the banana peel assessed using DPPH assay except for green PB peel, which 70% methanol had contributed to the highest AA. Highest TPC and AA were obtained by applying 4, 1, and 2 hrs extraction for the peels of PA, PB and PM, respectively. The best extraction conditions were also used for determination of AAs using ABTS and β-carotene bleaching assays. Therefore, the best extraction conditions used have given the highest TPC and AAs. By

  13. Tertiary sedimentary history and structure of the Valencia trough (western Mediterranean)

    NASA Astrophysics Data System (ADS)

    Maillard, A.; Mauffret, A.; Watts, A. B.; Torné, M.; Pascal, G.; Buhl, P.; Pinet, B.

    1992-03-01

    We present here main results of the Common Depth Point (CDP) data acquired during the Valsis 2 Cruise in 1988 in the Valencia trough. The profiles are tied in with industrial well data and this correlation allows the sedimentary and structural history of the region to be deduced. The Valsis Cruise seismic profiles have been supplemented by a very dense grid of industrial seismic lines and these data permit us to establish an accurate depth to basement map. The formation of the initial grabens, coeval with those of the Gulf of Lions, is related to the Early Miocene opening of the northwestern Mediterranean basin and the Barcelona graben is filled by the same sedimentary layers, including evaporites, as that of the Provençal region. Nevertheless, the Valencia-Catalan grabens have been reactivated by young extensional tectonics which could be a consequence of the convergence of Africa relative to Europe. The Valencia trough is segmented by transfer faults which trend NW-SE. These faults, which have a more accentuated structural expression than the Valencia and Catalonia grabens, may act as transform faults separating the individual Balearic Islands. The transfer faults are in strike with volcanic ridges which have been sampled during the DSDP Leg 13. The dense seismic grid allows us to delineate several widespread volcanic features in the Valencia trough which have been active from the Early Miocene to the Pleistocene. However, we note that the volcanic features are mainly Miocene in age whereas the recent volcanism is restricted to a narrow zone (Columbretes Islands). The compressional tectonics which deformed the Balearic Islands does not appear to extend far towards the North. We delineate the compressional front north of Ibiza, but we failed to determine any thrust or fold north of Mallorca, whereas an extensional tectonics is evident.

  14. Temperature field for radiative tomato peeling

    NASA Astrophysics Data System (ADS)

    Cuccurullo, G.; Giordano, L.

    2017-01-01

    Nowadays peeling of tomatoes is performed by using steam or lye, which are expensive and polluting techniques, thus sustainable alternatives are searched for dry peeling and, among that, radiative heating seems to be a fairly promising method. This paper aims to speed up the prediction of surface temperatures useful for realizing dry-peeling, thus a 1D-analytical model for the unsteady temperature field in a rotating tomato exposed to a radiative heating source is presented. Since only short times are of interest for the problem at hand, the model involves a semi-infinite slab cooled by convective heat transfer while heated by a pulsating heat source. The model being linear, the solution is derived following the Laplace Transform method. A 3D finite element model of the rotating tomato is introduced as well in order to validate the analytical solution. A satisfactory agreement is attained. Therefore, two different ways to predict the onset of the peeling conditions are available which can be of help for proper design of peeling plants. Particular attention is paid to study surface temperature uniformity, that being a critical parameter for realizing an easy tomato peeling.

  15. A Case of Peeling Skin Syndrome.

    PubMed

    Singhal, Anil K; Yadav, Devendra K; Soni, Bajrang; Arya, Savita

    2017-01-01

    Peeling skin syndrome is a very rare autosomal recessive disease characterized by widespread painless peeling of the skin in superficial sheets. Etiology is still unknown with an autosomal recessive inheritance. Less than 100 cases have been reported in the medical literature. We present a 32-year-old man having asymptomatic peeling of skin since birth. Sheets of skin were peeling from his neck, trunk, and extremities, following friction or rubbing especially if pre-soaked in water but sparing palm and soles. Histologically, there was epidermal separation at the level of stratum corneum, just above the stratum granulosum. This case is being presented due to its rarity.

  16. A Case of Peeling Skin Syndrome

    PubMed Central

    Singhal, Anil K.; Yadav, Devendra K.; Soni, Bajrang; Arya, Savita

    2017-01-01

    Peeling skin syndrome is a very rare autosomal recessive disease characterized by widespread painless peeling of the skin in superficial sheets. Etiology is still unknown with an autosomal recessive inheritance. Less than 100 cases have been reported in the medical literature. We present a 32-year-old man having asymptomatic peeling of skin since birth. Sheets of skin were peeling from his neck, trunk, and extremities, following friction or rubbing especially if pre-soaked in water but sparing palm and soles. Histologically, there was epidermal separation at the level of stratum corneum, just above the stratum granulosum. This case is being presented due to its rarity. PMID:28584761

  17. Peeling of tomatoes using novel infrared radiation heating technology

    USDA-ARS?s Scientific Manuscript database

    The effectiveness of using infrared (IR) dry-peeling as an alternative process for peeling tomatoes without lye and water was studied. Compared to conventional lye peeling, IR dry-peeling using 30 s to 75 s heating time resulted in lower peeling loss (8.3% - 13.2% vs. 12.9% - 15.8%), thinner thickne...

  18. Lactic acid production from potato peel waste by anaerobic sequencing batch fermentation using undefined mixed culture.

    PubMed

    Liang, Shaobo; McDonald, Armando G; Coats, Erik R

    2015-11-01

    Lactic acid (LA) is a necessary industrial feedstock for producing the bioplastic, polylactic acid (PLA), which is currently produced by pure culture fermentation of food carbohydrates. This work presents an alternative to produce LA from potato peel waste (PPW) by anaerobic fermentation in a sequencing batch reactor (SBR) inoculated with undefined mixed culture from a municipal wastewater treatment plant. A statistical design of experiments approach was employed using set of 0.8L SBRs using gelatinized PPW at a solids content range from 30 to 50 g L(-1), solids retention time of 2-4 days for yield and productivity optimization. The maximum LA production yield of 0.25 g g(-1) PPW and highest productivity of 125 mg g(-1) d(-1) were achieved. A scale-up SBR trial using neat gelatinized PPW (at 80 g L(-1) solids content) at the 3 L scale was employed and the highest LA yield of 0.14 g g(-1) PPW and a productivity of 138 mg g(-1) d(-1) were achieved with a 1 d SRT. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Antioxidative properties of defatted dabai pulp and peel prepared by solid phase extraction.

    PubMed

    Khoo, Hock Eng; Azlan, Azrina; Ismail, Amin; Abas, Faridah

    2012-08-14

    Solid phase extraction (SPE) using Sep-Pak® cartridges is one of the techniques used for fractionation of antioxidant compounds in waste of dabai oil extraction (defatted dabai parts). The aim of this study was to determine the phenolic compounds and antioxidant capacity in crude extracts and several SPE fractions from methanolic extract of defatted dabai pulp and peel. Based on SPE, Sep-Pak® cyanopropyl and C₁₈ cartridges were used to fractionate the antioxidant-rich crude extracts into water and methanolic fractions. Analyzed using LC-MS, flavonoids, anthocyanins, saponin derivatives and other unknown antioxidative compounds were detected in the defatted dabai crude extracts and their SPE fractions. Anthocyanins were the major phenolic compounds identified in the defatted dabai peel and detected in most of the SPE fractions. Methanolic fractions of defatted dabai parts embraced higher total phenolics and antioxidant capacity than water fractions. This finding also revealed the crude extracts of defatted dabai peel have the most significant antioxidant properties compared to the methanolic and water fractions studied. The crude extract of defatted dabai parts remain as the most potent antioxidant as it contains mixture of flavonoids, anthocyanins and other potential antioxidants.

  20. Work, rice and malaria in Valencia in the XVIIIth century.

    PubMed

    Riera Palmero, J

    1994-01-01

    This study, prepared with documentary sources from archives, focuses on one of the most serious health problems in Spain in the age of Enlightenment; that is, the pernicious endemics of malaria in the humid Mediterranean zones. Based on material from the General Archives of Simancas, the author studies the health polemic between the partisans and detractors of rice cultivation in the swampy bogs of the Turia and Júcar river areas. To these considerations on Valencia's agricultural expansion in the 18th century is added a documented study on malaria in the ancient kingdom of Valencia, a theme which underlies this historiographic contribution.

  1. NuMex-02- A High oleic Valencia peanut with partial resistance to Sclerotinia blight

    USDA-ARS?s Scientific Manuscript database

    NuMex-02 is a high oleic Valencia peanut (Arachis hypogaea L., subsp. fastigiata var. fastigiata) cultivar developed by the New Mexico Agricultural Experiment Station, Clovis, New Mexico. NuMex-02 originated from a cross made between NM Valencia A and OLin. Pedigree selection was practiced based on...

  2. In vitro Study of Noni Juice Extract Waste (Morinda citrifolia L.) and Pineapple Industrial Wastes (Ananas comosus L. Merr) as Energy Supplement in Dairy Goat Ration

    NASA Astrophysics Data System (ADS)

    Evvyernie, D.; Tjakradidjaja, A. S.; Permana, I. G.; Toharmat, T.; Insani, A.

    2018-02-01

    The aim of the study was to evaluate the potency of noni juice extract waste (Morinda citrifolia L.) and pineapple industrial wastes (Ananas comosus L. Merr) as an energy supplement in dairy goat ration through in vitro study. This study used a complete randomized design with 5 treatments and 3 rumen fluid groups. The treatments were R0 as control (60% Napier grass (NG) + 40% concentrate), R1 (45% NG + 15% noni juice extract waste + 40% concentrate) + R2 (45% NG + 15% noni juice extract waste ammoniated + 40% concentrate), R3 (45% NG + 15% pineapple peel + 40% concentrate), and R4 (45% NG + 15% pineapple crown + 40% concentrate). The variables were totalbacterial population, protozoal population, fermentation characteristic (total VFA and NH3 concentration), and digestibility (dry matter and organic matter).Data were analyzed with analysis of variance (ANOVA) and differences among treatments were determined by orthogonal contrast.The results showed that total VFA concentration was significant increased (P<0.05) by replacing 25% napier grass with noni juice extract waste (R1)or very significant increased(P<0.01) by replacing the grass with pineapple peel (R3). The average increasing of total VFA concentration was 74% compared to control. As conclusions, 15% pineapple peel or 15% noni juice extract waste can use as an energy supplement by replacing 25% of napier grass in lactating dairy goat ration.

  3. Vitrectomy with internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole.

    PubMed

    Spiteri Cornish, Kurt; Lois, Noemi; Scott, Neil W; Burr, Jennifer; Cook, Jonathan; Boachie, Charles; Tadayoni, Ramin; la Cour, Morten; Christensen, Ulrik; Kwok, Alvin K H

    2014-03-01

    To determine whether internal limiting membrane (ILM) peeling improves anatomic and functional outcomes of full-thickness macular hole (FTMH) surgery when compared with the no-peeling technique. Systematic review and individual participant data (IPD) meta-analysis undertaken under the auspices of the Cochrane Eyes and Vision Group. Only randomized controlled trials (RCTs) were included. Patients with idiopathic stage 2, 3, and 4 FTMH undergoing vitrectomy with or without ILM peeling. Macular hole surgery, including vitrectomy and gas endotamponade with or without ILM peeling. Primary outcome was best-corrected distance visual acuity (BCdVA) at 6 months postoperatively. Secondary outcomes were BCdVA at 3 and 12 months; best-corrected near visual acuity (BCnVA) at 3, 6, and 12 months; primary (after a single surgery) and final (after >1 surgery) macular hole closure; need for additional surgical interventions; intraoperative and postoperative complications; patient-reported outcomes (PROs) (EuroQol-5D and Vision Function Questionnaire-25 scores at 6 months); and cost-effectiveness. Four RCTs were identified and included in the review. All RCTs were included in the meta-analysis; IPD were obtained from 3 of the 4 RCTs. No evidence of a difference in BCdVA at 6 months was detected (mean difference, -0.04; 95% confidence interval [CI], -0.12 to 0.03; P=0.27); however, there was evidence of a difference in BCdVA at 3 months favoring ILM peeling (mean difference, -0.09; 95% CI, -0.17 to-0.02; P=0.02). There was evidence of an effect favoring ILM peeling with regard to primary (odds ratio [OR], 9.27; 95% CI, 4.98-17.24; P<0.00001) and final macular hole closure (OR, 3.99; 95% CI, 1.63-9.75; P=0.02) and less requirement for additional surgery (OR, 0.11; 95% CI, 0.05-0.23; P<0.00001), with no evidence of a difference between groups with regard to intraoperative or postoperative complications or PROs. The ILM peeling was found to be highly cost-effective. Available evidence

  4. Effect of chemical peeling on photocarcinogenesis.

    PubMed

    Abdel-Daim, Mohamed; Funasaka, Yoko; Kamo, Tsuneyoshi; Ooe, Masahiko; Matsunaka, Hiroshi; Yanagita, Emmy; Itoh, Tomoo; Nishigori, Chikako

    2010-10-01

    Chemical peeling is one of the dermatological treatments available for certain cutaneous diseases and conditions or improvement of cosmetic appearance of photo-aged skin. We assessed the photo-chemopreventive effect of several clinically used chemical peeling agents on the ultraviolet-irradiated skin of hairless mice. Chemical peeling was done using 35% glycolic acid dissolved in distilled water, 30% salicylic acid in ethanol, and 10% or 35% trichloroacetic acid in distilled water at the right back of ultraviolet-irradiated hairless mice every 2 weeks for glycolic acid, salicylic acid and 10% trichloroacetic acid, and every 4 weeks for 35% trichloroacetic acid for a total of 18 weeks after the establishment of photo-aged mice by irradiation with ultraviolet B range light three times a week for 14 weeks at a total dose of 6.66 J/cm(2) . Tumor formation was assessed every week. Skin specimens were taken from treated and non-treated area for evaluation under microscopy, evaluation of p53 expression and mRNA expression of cyclooxygenase-2. Serum level of prostaglandin E(2) was also evaluated. All types of chemical peeling reduced tumor formation in treated mice, mostly in the treated area but also in the non-treated area. Peeling suppressed retention of p53-positive abnormal cells and reduced mRNA expression of cyclooxygenase-2 in treated skin. Further, serum prostaglandin E(2) level was decreased in chemical peeling treated mice. These results indicate that chemical peeling with glycolic acid, salicylic acid and trichloroacetic acid could serve tumor prevention by removing photo-damaged cells. © 2010 Japanese Dermatological Association.

  5. [Drusen characteristics after internal limiting membrane peeling].

    PubMed

    Lehmann, F; Jenisch, T; Helbig, H; Gamulescu, M A

    2015-05-01

    There are some reports showing isolated cases of drusen regression after pars plana vitrectomy (ppV) with peeling of the internal limiting membrane (iLM). Drusen characteristics after iLM peeling was investigated in this study. The data of 527 patients who had received iLM peeling between 2004 and 2012 were retrospectively collected and those patients with retinal drusen were selected for the study. Fundus photographs before and after vitrectomy due to a macular hole or epiretinal gliosis were compared and drusen arrangement in the peeling site was analyzed. The aim of the study was to show whether there was drusen regression 2-5 months after surgery. Out of the 527 patients 11 showed central macular drusen, 4 with confluent large drusen (> 63 µm diameter) and 7 with small hard drusen (≤ 63 µm diameter). One patient showed drusen regression after iLM peeling without any changes in the other eye and all other patients showed no differences in the drusen findings (n = 6) or even some additional drusen (n = 4) without drusen alterations in the other eye. The results of this study could not confirm some reports showing drusen regression after iLM peeling in the peeling site in general and there was only one single case of central drusen regression.

  6. Identification of the bioactive compounds and antioxidant, antimutagenic and antimicrobial activities of thermally processed agro-industrial waste.

    PubMed

    Vodnar, Dan Cristian; Călinoiu, Lavinia Florina; Dulf, Francisc Vasile; Ştefănescu, Bianca Eugenia; Crişan, Gianina; Socaciu, Carmen

    2017-09-15

    The purpose of the research was to identify the bioactive compounds and to evaluate the antioxidant, antimutagenic and antimicrobial activities of the major Romanian agro-industrial wastes (apple peels, carrot pulp, white- and red-grape peels and red-beet peels and pulp) for the purpose of increasing the wastes' value. Each type of waste material was analyzed without (fresh) and with thermal processing (10min, 80°C). Based on the obtained results, the thermal process enhanced the total phenolic content. The highest antioxidant activity was exhibited by thermally processed red-grape waste followed by thermally processed red-beet waste. Linoleic acid was the major fatty acid in all analyzed samples, but its content decreased significantly during thermal processing. The carrot extracts have no antimicrobial effects, while the thermally processed red-grape waste has the highest antimicrobial effect against the studied strains. The thermally processed red-grape sample has the highest antimutagenic activity toward S. typhimurium TA98 and TA100. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Rambutan peels promoted biomimetic synthesis of bioinspired zinc oxide nanochains for biomedical applications.

    PubMed

    Yuvakkumar, R; Suresh, J; Saravanakumar, B; Joseph Nathanael, A; Hong, Sun Ig; Rajendran, V

    2015-02-25

    A naturally occurring rambutan peel waste was employed to synthesis bioinspired zinc oxide nanochains. Rambutan peels has the ability of ligating zinc ions as a natural ligation agent resulting in zinc oxide nanochains formation due to its extended polyphenolic system over incubation period. Successful formation of zinc oxide nanochains was confirmed employing transmission electron microscopy studies. About 60% and ∼40% cell viability was lost and 50% and 10% morphological change was observed in 7 and 4 days incubated ZnO treated cells compared with control. Moreover, 50% and 55% of cell death was observed at 24 and 48 h incubation with 7 days treated ZnO cells and hence alters and disturbs the growth of cancer cells and could be used for liver cancer cell treatment. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Clinical efficacy and safety of 20% glycolic peel, 15% lactic peel, and topical 20% vitamin C in constitutional type of periorbital melanosis: a comparative study.

    PubMed

    Dayal, Surabhi; Sahu, Priyadarshini; Jain, Vijay Kumar; Khetri, Sneh

    2016-12-01

    Periorbital Melanosis (POM) is a very common esthetic condition, yet there is no definite treatment modality. Topical therapy is the mainstay of treatment which includes chemical peels, vitamin C, and other depigmenting agents. To compare clinical efficacy, safety, and tolerability of 20% glycolic acid peels, 15% lactic acid peels, and topical 20% vitamin C in treatment of constitutional type of POM in Indian patients. Ninety patients of constitutional POM were enrolled for 12 weeks. The patients were distributed into three groups. One-third of patients underwent 3-weekly GA peel, another one-third underwent 3-weekly lactic peel, and rest applied vitamin C daily. Clinical improvement was assessed objectively using POM grading. Patient's and physicians global assessment along with patient's global tolerance was also evaluated. More than 50% improvement in POM was observed in 73.34% of patients on GA peel, 56.67% on lactic peel, and 26.67% on vitamin C. On comparing improvement with respect to duration of therapy, GA peel was significantly more effective than lactic peel from 12 weeks onward, while it was more effective than vitamin C from 6 weeks onward. Lactic peel was more effective than vitamin C from 6 weeks onward. Physician and patient global assessment was excellent with glycolic peel followed by lactic peel and vitamin C. The incidence of adverse effect was maximum with GA peel followed by lactic peel and vitamin C. Glycolic peel was best among the three modalities, although it was associated with increased rate of side effects. © 2016 Wiley Periodicals, Inc.

  9. Comparison between 1% tretinoin peeling versus 70% glycolic acid peeling in the treatment of female patients with melasma.

    PubMed

    Faghihi, Gita; Shahingohar, Anahita; Siadat, Amir Hossein

    2011-12-01

    Melasma is an irregular brownish pigmentation observed on the faces of young to middle-aged women, especially of Asian races, which may contribute to various emotional disturbances. Although not any favorable treatment being approved yet, one appropriate approach is peeling by glycolic acid 70% (GA 70%). Considering the efficiency of Tretinoin in lower concentrations as over-the-counter lightening agents, peelings with higher strength Tretinoin may effectively relieve the pigmentation (melasma) sooner than other topical therapies. The main purpose was to compare the efficiency and complications of GA 70% with Tretinoin 1% peeling. A randomized, double-blinded clinical trial performed on 63 female patients with bilateral melasma. One facial side was treated by drug A (GA 70%) and the opposite side by agent B (Tretinoin 1%) peeling for four sessions with 2-week intervals. Descending changes in Melasma Area and Severity Index (MASI) scores, patients' discomfort and untoward complications following peeling all were evaluated and compared during the research period. The efficiency of Tretinoin 1% peelings in declining the MASI score (treatment of melasma) was similar to GA 70%, as well as the rare unwanted complications of them. However, the patients' discomfort following procedures as expressed by their own, was significantly lower with Tretinoin 1% compared to GA 70% peeling. The cases' satisfaction with the intervention was statistically similar to each other. Furthermore, we experienced almost the equal times of beginning the therapeutic responses in both groups.

  10. Influence of skin peeling procedure in allergic contact dermatitis.

    PubMed

    Kim, Jung Eun; Park, Hyun Jeong; Cho, Baik Kee; Lee, Jun Young

    2008-03-01

    The prevalence of allergic contact dermatitis in patients who have previously undergone skin peeling has been rarely studied. We compared the frequency of positive patch test (PT) reactions in a patient group with a history of peeling, to that of a control group with no history of peeling. The Korean standard series and cosmetic series were performed on a total of 262 patients. 62 patients had previously undergone peeling and 200 patients did not. The frequency of positive PT reactions on Korean standard series was significantly higher in the peeling group compared with that of the control group (P < 0.05, chi-square test). However, the most commonly identified allergens were mostly cosmetic-unrelated allergens. The frequency of positive PT reactions on cosmetic series in the peeling group was higher than that of the control group, but lacked statistical significance. The frequency (%) of positive PT reactions on cosmetic series in the high-frequency peel group was higher than that of the low-frequency group, but lacked statistical significance. It appears peeling may not generally affect the development of contact sensitization. Further work is required focusing on the large-scale prospective studies by performing a PT before and after peeling.

  11. Chemical Peeling: A Useful Tool in the Office.

    PubMed

    Truchuelo, M; Cerdá, P; Fernández, L F

    2017-05-01

    Chemical peeling is a common treatment in cosmetic dermatology. A peel that has been used for many years is trichloroacetic acid. Its adverse effects have for a long time been a major limitation. We present a practical review of the characteristics, mechanisms of action, indications, and complications of superficial chemical peels and of peeling with trichloroacetic acid. Copyright © 2016 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.

  12. Evaluation of the suitability and performance of cassava waste (peel) extracts in a microbial fuel cell for supplementary and sustainable energy production.

    PubMed

    Adekunle, Ademola; Raghavan, Vijaya

    2017-01-01

    In a number of energy-poor nations, peel from cassava processing represents one of the most abundant sources of lignocellulosic biomass. This peel is mostly discarded indiscriminately and eventually constitutes a problem to the environment. However, energy can be extracted from this peel in a microbial fuel cell. In this study, the viability of cassava peel extract as a substrate in a single-chamber air cathode microbial fuel cell is demonstrated, and optimum performance conditions are explored. The effects of different pretreatments on the extract are also discussed in the context of observed changes in the internal resistances, conductivity and Coulombic efficiencies. At the best conditions examined, the extract from cassava peel fermented for 168 h and adjusted to a pH of 7.63 attained a peak voltage of 687 mV ± 21 mV, a power density of 155 mW m -3 of reactor volume and a Coulombic efficiency of 11 %. Although this energy is limited to direct use, systems exist that can effectively harvest and boost the energy to levels sufficient for supplementary energy usage in cassava producing regions.

  13. Vitrectomy with internal limiting membrane peeling vs no peeling for Macular Hole-induced Retinal Detachment (MHRD): a meta-analysis.

    PubMed

    Su, Jing; Liu, Xinquan; Zheng, Lijun; Cui, Hongping

    2015-06-20

    we conducted our meta-analysis of published studies to assess existing evidence about the efficacy and safety of vitrectomy with ILM peeling vs. that of vitrectomy with no ILM peeling for Macular hole-induced retinal detachment. Databases, including Pubmed, Cochrane Library, Ovid, Web of Science, Wanfang and CNKI, were searched to identify studies comparing outcomes following vitrectomy with ILM peeling and that with no ILM peeling for macular hole-induced retinal detachment. The meta-analysis was performed by RevMan 5.1. Six comparative studies comprising 180 eyes were identified. It was indicated that the rate of retinal reattachment (Odds ratio (OR) = 3.03, 95 % Confidence interval (CI):1.35 to 6.78; P = 0.007) and macular hole closure (OR = 6.74, 95 % CI:3.26 to 13.93; P < 0.001) after initial surgery was higher and the rate of recurrent retinal detachment (OR = 0.08, 95 % CI:0.02 to 0.30; P = 0.0002) was lower in the group of vitrectomy with ILM peeling than that in the group of vitrectomy with no ILM peeling. However, the improved BCVA (Weighted mean difference (WMD) = 0.14, 95 % CI: -0.20 to 0.47; P = 0.42) and the rate of postoperative complications were similar between the two groups. Vitrectomy with internal limiting membrane peeling is an efficient and safe procedure for macular hole-induced retinal detachment.

  14. Profiling of bioactive compounds in cultivars of Runner and Valencia peanut market-types using liquid chromatography/APCI mass spectrometry.

    PubMed

    Chukwumah, Yvonne; Walker, Lloyd; Vogler, Bernhard; Verghese, Martha

    2012-05-01

    Peanuts are classified into four market-types (Runners, Spanish, Virginia and Valencia). Studies on their phytochemical composition have focused mainly on market-types other than Valencia. The objectives of this study are to evaluate the phytochemical composition of cultivars of Valencia and Runner market-types. Extracts of 25 peanut cultivars of Runner and Valencia market-types were analysed using HPLC-DAD-MS analysis. Results showed major differences in UV profile of the market-types. A major peak with m/z 317 identified as isorhamnetin was present only in Valencia cultivars while its glycoside (isorhamnetin-3-O-rutinoside) having m/z 625 was identified in both market-types. Genistein, daidzein, rutin, quercetin and trans-resveratrol were also identified and quantified. Genistein and daidzein concentrations (0.03mg/100g) were similar in both market-types. trans-Resveratrol and rutin were significantly (p<0.05) higher in Runner cultivars while quercetin was 10-fold higher (0.60±0.04mg/100g) in Valencia cultivars making them a better source of this phytochemical. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. The role of peel stresses in cyclic debonding

    NASA Technical Reports Server (NTRS)

    Everett, R. A., Jr.

    1982-01-01

    When an adhesively bonded joint is undergoing cyclic loading, one of the possible damage modes that occurs is called cyclic debonding - progressive separation of the adherends by failure of the adhesive bond under cyclic loading. In most practical structures, both peel and shear stresses exist in the adhesive bonding during cyclic loading. The results of an experimental and analytical study to determine the role of peel stresses on cyclic debonding in a mixed mode specimen are presented. Experimentally, this was done by controlling the forces that create the peel stresses by applying a clamping force to oppose the peel stresses. Cracked lap shear joints were chosen for this study. A finite element analysis was developed to assess the effect of the clamping force on the strain energy release rates due to shear and peel stresses. The results imply that the peel stress is the principal stress causing cyclic debonding.

  16. Chemical peels in active acne and acne scars.

    PubMed

    Kontochristopoulos, Georgios; Platsidaki, Eftychia

    Chemical peeling is a widely used procedure in the management of acne and acne scars. It causes controlled destruction of a part of or the entire epidermis, with or without the dermis, leading to exfoliation and removal of superficial lesions, followed by regeneration of new epidermal and dermal tissues. The most frequently used peeling agents are salicylic acid, glycolic acid, pyruvic acid, lactic acid, mandelic acid, Jessner solution, trichloroacetic acid, and phenol. The appropriate peel is chosen based on the patient's skin type, acne activity, and type of acne scars. Combination peels minimize side effects. In acne scars, chemical peels may be combined with other procedures to achieve better clinical results. A series of chemical peels can lead to significant improvement over a short period, leading to patient satisfaction and maintenance of clinical results. © 2016 Elsevier Inc. All rights reserved. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Simplex-centroid mixture formulation for optimised composting of kitchen waste.

    PubMed

    Abdullah, N; Chin, N L

    2010-11-01

    Composting is a good recycling method to fully utilise all the organic wastes present in kitchen waste due to its high nutritious matter within the waste. In this present study, the optimised mixture proportions of kitchen waste containing vegetable scraps (V), fish processing waste (F) and newspaper (N) or onion peels (O) were determined by applying the simplex-centroid mixture design method to achieve the desired initial moisture content and carbon-to-nitrogen (CN) ratio for effective composting process. The best mixture was at 48.5% V, 17.7% F and 33.7% N for blends with newspaper while for blends with onion peels, the mixture proportion was 44.0% V, 19.7% F and 36.2% O. The predicted responses from these mixture proportions fall in the acceptable limits of moisture content of 50% to 65% and CN ratio of 20-40 and were also validated experimentally. Copyright 2010 Elsevier Ltd. All rights reserved.

  18. Comparison of carotenoid accumulation and biosynthetic gene expression between Valencia and Rohde Red Valencia sweet oranges.

    PubMed

    Wei, Xu; Chen, Chunxian; Yu, Qibin; Gady, Antoine; Yu, Yuan; Liang, Guolu; Gmitter, Frederick G

    2014-10-01

    Carotenoid accumulation and biosynthetic gene expression levels during fruit maturation were compared between ordinary Valencia (VAL) and its more deeply colored mutant Rohde Red Valencia orange (RRV). The two cultivars exhibited different carotenoid profiles and regulatory mechanisms in flavedo and juice sacs, respectively. In flavedo, there was uncoordinated carotenoid accumulation and gene expression in RRV during green stages, which might be related to the expression of certain gene(s) in the MEP (methylerythritol phosphate) pathway. The carotenoid biosynthesis pathway shifting from α,β-xanthophylls to β,β-xanthophylls synthesis occurred in RRV earlier than VAL during orange stages. In juice sacs, the low carotenoid content in both cultivars coincided with low expression of LCYE-Contig03 and LCYE-Contig24 during green stages, suggesting LCYE might be a limiting step for carotenoid accumulation. VAL mainly accumulated violaxanthin, but RRV accumulated β-cryptoxanthin and violaxanthin during orange stages, which corresponded to differences in juice color. Several upstream genes (PDS-Contig17, LCYB-Contig19, and ZDS members) and a downstream gene (ZEP) were expressed at higher levels in RRV than VAL, which might be responsible for greater accumulation of β-cryptoxanthin and violaxanthin in RRV, respectively. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  19. Development of infrared heating technology for tomato peeling

    USDA-ARS?s Scientific Manuscript database

    The commercial lye and steam peeling methods used in tomato processing industry are water- and energy-intensive and have a negative impact on the environment. To develop alternative peeling methods, we conducted comprehensive studies of using infrared (IR) heating for tomato peeling. The three major...

  20. Novel green synthetic strategy to prepare ZnO nanocrystals using rambutan (Nephelium lappaceum L.) peel extract and its antibacterial applications.

    PubMed

    Yuvakkumar, R; Suresh, J; Nathanael, A Joseph; Sundrarajan, M; Hong, S I

    2014-08-01

    In the present investigation, we report a sustainable novel green synthetic strategy to synthesis zinc oxide nanocrystals. This is the first report on sustainable biosynthesis of zinc oxide nanocrystals employing Nephelium lappaceum L., peel extract as a natural ligation agent. Green synthesis of zinc oxide nanocrystals was carried out via zinc-ellagate complex formation using rambutan peel wastes. The successful formation of zinc oxide nanocrystals was confirmed employing standard characterisation studies. A possible mechanism for the formation of ZnO nanocrystals with rambutan peel extract was also proposed. The prepared ZnO nanocrystals were coated on the cotton fabric and their antibacterial activity were analyzed. ZnO nanocrystals coated cotton showed good antibacterial activity towards Escherichia coli (E. coli), gram negative bacteria and Staphylococcus aureus (S. aureus), gram positive bacteria. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. [Chemical and biological evaluation of ripe banana peel].

    PubMed

    Ranzani, M R; Sturion, G L; Bicudo, M H

    1996-12-01

    Chemical and biological evaluation of ripe banana peel was conducted, aiming its potential use as a source of dietary fiber in human nutrition. Two types of flour were prepared from banana peel: a) untreated (UT), using washed and dried peel; b) treated (SMB), using peel treated with sodium metabisulfite and citric acid, in attempt to minimize the darkening of the flour. As expected, banana peel flour revealed to be an important source of fiber (NDF), corresponding about 32% of its dried weight. The addition of this flour to a basal casein diet lowered its protein digestibility and increased the fecal bulk of the rats, which are the known effects of dietary fiber. However, it did not alter the protein quality, since there was no difference in the PER values of the diets studied; in addition, the growth of the rats fed diets containing banana peel did not differ from those fed control diet. These results suggest the feasibility of technological studies aiming the development of food products with banana peel. Besides, biological assays should be realized in the elucidation of its effects in food intake and biochemical parameters.

  2. Effect of the concentration of essential oil on orange peel waste biomethanization: Preliminary batch results.

    PubMed

    Calabrò, P S; Pontoni, L; Porqueddu, I; Greco, R; Pirozzi, F; Malpei, F

    2016-02-01

    The cultivation of orange (Citrus×sinensis) and its transformation is a major industry in many countries in the world, it leads to the production of about 25-30Mt of orange peel waste (OPW) per year. Until now many options have been proposed for the management of OPW but although they are technically feasible, in many cases their economic/environmental sustainability is questionable. This paper analyse at lab scale the possibility of using OPW as a substrate for anaerobic digestion. Specific objectives are testing the possible codigestion with municipal biowaste, verifying the effect on methane production of increasingly high concentration of orange essential oil (EO, that is well known to have antioxidant properties that can slower or either inhibit biomass activity) and obtaining information on the behaviour of d-limonene, the main EO component, during anaerobic digestion. The results indicate that OPW can produce up to about 370LnCH4/kgVS in mesophilic conditions and up to about 300LnCH4/kgVS in thermophilic conditions. The presence of increasingly high concentrations of EO temporary inhibits methanogenesis, but according to the results of batch tests, methane production restarts while d-limonene is partially degraded through a pathway that requires its conversion into p-cymene as the main intermediate. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. A hepatonephro-protective phenolic-rich extract from red onion (Allium cepa L.) peels.

    PubMed

    Ahmed, Atallah F; Al-Yousef, Hanan M; Al-Qahtani, Jawaher H; Al-Said, Mansour S

    2017-09-01

    Onion peel is a common bio-waste, occasionally used in traditional medicine in treatment of liver ailment and inflammation. However, a phytochemical and biological study is further required to provide the scientific evidence for this use. A phenolic-rich extract of red onion peels (coded as ACPE) was primarily prepared and then subjected to chromatographic separation. From the extract, six phenolic antioxidant compounds along with two phytosterols were isolated and identified by means of spectroscopic (NMR and MS) analyses. The in vivo protective activity of the ACPE against the oxidative stress induced by carbon tetrachloride (CCl4) free radicals, in liver and kidney, was assessed in rats. Relative to the CCl4-challenged animals, pre-treatment with ACPE could significantly ameliorate the hepatonephrolinked serum and tissue markers in a dose-dependent response. The flavonol- and phenolic acid-based nature of constituents, the high phenolic content (72.33±5.30 mg gallic acid equivalent per one gram) and the significant antioxidant capacity (>1/3 potency of rutin) of ACPE may be thus attributed strongly to the hepatonephro-protective and anti-inflammatory effect of ACPE. The results suggest that red onion peels can serve as a convenient and cost-effective source of high-value antioxidant nutraceuticals for protection against oxidative stress-related disorders.

  4. Submerged citric acid fermentation on orange peel autohydrolysate.

    PubMed

    Rivas, Beatriz; Torrado, Ana; Torre, Paolo; Converti, Attilio; Domínguez, José Manuel

    2008-04-09

    The citrus-processing industry generates in the Mediterranean area huge amounts of orange peel as a byproduct from the industrial extraction of citrus juices. To reduce its environmental impact as well as to provide an extra profit, this residue was investigated in this study as an alternative substrate for the fermentative production of citric acid. Orange peel contained 16.9% soluble sugars, 9.21% cellulose, 10.5% hemicellulose, and 42.5% pectin as the most important components. To get solutions rich in soluble and starchy sugars to be used as a carbon source for citric acid fermentation, this raw material was submitted to autohydrolysis, a process that does not make use of any acidic catalyst. Liquors obtained by this process under optimum conditions (temperature of 130 degrees C and a liquid/solid ratio of 8.0 g/g) contained 38.2 g/L free sugars (8.3 g/L sucrose, 13.7 g/L glucose, and 16.2 g/L fructose) and significant amounts of metals, particularly Mg, Ca, Zn, and K. Without additional nutrients, these liquors were employed for citric acid production by Aspergillus niger CECT 2090 (ATCC 9142, NRRL 599). Addition of calcium carbonate enhanced citric acid production because it prevented progressive acidification of the medium. Moreover, the influence of methanol addition on citric acid formation was investigated. Under the best conditions (40 mL of methanol/kg of medium), an effective conversion of sugars into citric acid was ensured (maximum citric acid concentration of 9.2 g/L, volumetric productivity of 0.128 g/(L.h), and yield of product on consumed sugars of 0.53 g/g), hence demonstrating the potential of orange peel wastes as an alternative raw material for citric acid fermentation.

  5. Valencia Community College Educational Technology Plan, 2000-2004.

    ERIC Educational Resources Information Center

    Valencia Community Coll., Orlando, FL.

    The purpose of the Educational Technology Plan is to provide a collaborative framework to address the institutional assessment, prioritization, implementation, and resource allocation associated with technology issues at Valencia Community College (Florida). The plan has been integrated with the college's Comprehensive Strategic Plan goals and…

  6. Chemical peeling in ethnic skin: an update.

    PubMed

    Salam, A; Dadzie, O E; Galadari, H

    2013-10-01

    With the growth of cosmetic dermatology worldwide, treatments that are effective against skin diseases and augment beauty without prolonged recovery periods, or exposing patients to the risks of surgery, are increasing in popularity. Chemical peels are a commonly used, fast, safe and effective clinic room treatment that may be used for cosmetic purposes, such as for fine lines and photoageing, but also as primary or adjunct therapies for acne, pigmentary disorders and scarring. Clinicians are faced with specific challenges when using peels on ethnic skin (skin of colour). The higher risk of postinflammatory dyschromias and abnormal scarring makes peels potentially disfiguring. Clinicians should therefore have a sound knowledge of the various peels available and their safety in ethnic skin. This article aims to review the background, classification, various preparations, indications, patient assessment and complications of using chemical peels in ethnic skin. © 2013 The Authors BJD © 2013 British Association of Dermatologists.

  7. Sorption of mercury onto waste material derived low-cost activated carbon

    NASA Astrophysics Data System (ADS)

    Bhakta, Jatindra N.; Rana, Sukanta; Lahiri, Susmita; Munekage, Yukihiro

    2017-03-01

    The present study was performed to develop the low-cost activated carbon (AC) from some waste materials as potential mercury (Hg) sorbent to remove high amount of Hg from aqueous phase. The ACs were prepared from banana peel, orange peel, cotton fiber and paper wastes by pyrolysis and characterized by analyzing physico-chemical properties and Hg sorption capacity. The Brunauer Emmett and Teller surface areas (cotton 138 m2/g; paper 119 m2/g), micropore surface areas (cotton 65 m2/g; paper 54 m2/g) and major constituent carbon contents (cotton 95.04 %; paper 94.4 %) were higher in ACs of cotton fiber and paper wastes than the rest two ACs. The Hg sorption capacities and removal percentages were greater in cotton and paper wastes-derived ACs compared to those of the banana and orange peels. The results revealed that elevated Hg removal ability of cotton and paper wastes-derived ACs is largely regulated by their surface area, porosity and carbon content properties. Therefore, ACs of cotton and paper wastes were identified as potential sorbent among four developed ACs to remove high amount of Hg from aqueous phase. Furthermore, easily accessible precursor material, simple preparation process, favorable physico-chemical properties and high Hg sorption capacity indicated that cotton and paper wastes-derived ACs could be used as potential and low-cost sorbents of Hg for applying in practical field to control the severe effect of Hg contamination in the aquatic environment to avoid its human and environmental health risks.

  8. Food peeling: conventional and new approaches

    USDA-ARS?s Scientific Manuscript database

    Peeling is an important unit operation in food processing that prepares fruits and vegetables for subsequent processes through removal of inedible or undesirable rind or skin. This chapter covers an exhaustive discussion on advancement in peeling technologies of fruits and vegetables from different ...

  9. Prediction of processing tomato peeling outcomes

    USDA-ARS?s Scientific Manuscript database

    Peeling outcomes of processing tomatoes were predicted using multivariate analysis of Magnetic Resonance (MR) images. Tomatoes were obtained from a whole-peel production line. Each fruit was imaged using a 7 Tesla MR system, and a multivariate data set was created from 28 different images. After ...

  10. Histological case-control study of peeling-induced skin changes by different peeling agents in surgically subcutaneous undermined skin flaps in facelift patients.

    PubMed

    Gonser, P; Kaestner, S; Jaminet, P; Kaye, K

    2017-11-01

    A histological evaluation of peeling-induced skin changes in subcutaneous undermined preauricular facial skin flaps of nine patients was performed. There were three treatment groups: Trichloroacetic acid (TCA) 25%, TCA 40% and phenol/croton oil; one group served as control. Two independent evaluators determined the epidermal and dermal thickness and the depth of necrosis (micrometre). The percentual tissue damage due to the peeling was calculated, and a one-sample t-test for statistical significance was performed. On the basis of the histomorphological changes, peeling depth was classified as superficial, superficial-partial, deep-partial and full thickness chemical burn. The histological results revealed a progression of wound depth for different peeling agents without full thickness necrosis. TCA peels of up to 40% can be safely applied on subcutaneous undermined facial skin flaps without impairing the vascular patency, producing a predictable chemical burn, whereas deep peels such as phenol/croton oil peels should not be applied on subcutaneous undermined skin so as to not produce skin slough or necrosis by impairing vascular patency. Copyright © 2017 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  11. Acral peeling skin syndrome: report of two cases.

    PubMed

    García, Elena García; Carreño, Rosario Granados; Martínez González, Miguel A; Reyes, José Jiménez

    2005-01-01

    Peeling skin syndrome is a rare dermatosis characterized by spontaneous and painless peeling of the skin. The authors report two patients with history of spontaneous, asymptomatic, and noninflammatory peeling skin of the acral surfaces after soaking in water. On light microscopy, blisters were located in the mid layers of the stratum corneum, above the granular layer. Ultrastructural examination revealed increased intercellular lipids and abnormal, "moth-eaten," keratohyalin granules, but the authors were unable to determine whether the separation initiated within the horny cells or between adjacent cells. These patients represented a localized variant of peeling skin syndrome.

  12. FT-IR and DFT study of lemon peel

    NASA Astrophysics Data System (ADS)

    Berezin, K. V.; Likhter, A. M.; Shagautdinova, I. T.; Chernavina, M. L.; Novoselova, A. V.

    2017-03-01

    Experimental FT-IR spectra of lemon peel are registered in the 650 - 3800 cm-1 range. The influence of peel artificial and natural dehydration on its vibrational spectrum is studied. The colored outer surface of lemon peel is proved not to have a significant impact on FT-IR spectrum. It is determined that only dehydration processes affect the FT-IR vibrational spectrum of the peel when a lemon is stored for 28 days under natural laboratory conditions. Polymer molecule models for dietary fibers, such as cellulose, hemicellulose, pectin, lignin, as well as hesperidin - flavonoid glycoside, and free moisture cluster are developed within the framework of DFT/B3LYP/6-31G(d) theoretical method. By implementing supramolecular approach, modeling of the vibrational FT-IR spectrum of lemon peel is carried out and its detailed theoretical interpretation is presented.

  13. Continuous extraction of phenolic compounds from pomegranate peel using high voltage electrical discharge.

    PubMed

    Xi, Jun; He, Lang; Yan, Liang-Gong

    2017-09-01

    Pomegranate peel, a waste generated from fruit processing industry, is a potential source of phenolic compounds that are known for their anti-oxidative properties. In this study, a continuous high voltage electrical discharge (HVED) extraction system was for the first time designed and optimized for phenolic compounds from pomegranate peel. The optimal conditions for HVED were: flow rate of materials 12mL/min, electrodes gap distance 3.1mm (corresponding to 29kV/cm of electric field intensity) and liquid to solid ratio 35mL/g. Under these conditions, the experimental yield of phenolic compounds was 196.7±6.4mg/g, which closely agreed with the predicted value (199.83mg/g). Compared with the warm water maceration, HVED method possessed higher efficiency for the extraction of phenolic compounds. The results demonstrated that HVED technique could be a very effective method for continuous extraction of natural compounds. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Cost-effectiveness of internal limiting membrane peeling versus no peeling for patients with an idiopathic full-thickness macular hole: results from a randomised controlled trial.

    PubMed

    Ternent, Laura; Vale, Luke; Boachie, Charles; Burr, Jennifer M; Lois, Noemi

    2012-03-01

    To determine whether internal limiting membrane (ILM) peeling is cost-effective compared with no peeling for patients with an idiopathic stage 2 or 3 full-thickness macular hole. A cost-effectiveness analysis was performed alongside a randomised controlled trial. 141 participants were randomly allocated to receive macular-hole surgery, with either ILM peeling or no peeling. Health-service resource use, costs and quality of life were calculated for each participant. The incremental cost per quality-adjusted life year (QALY) gained was calculated at 6 months. At 6 months, the total costs were on average higher (£424, 95% CI -182 to 1045) in the No Peel arm, primarily owing to the higher reoperation rate in the No Peel arm. The mean additional QALYs from ILM peel at 6 months were 0.002 (95% CI 0.01 to 0.013), adjusting for baseline EQ-5D and other minimisation factors. A mean incremental cost per QALY was not computed, as Peeling was on average less costly and slightly more effective. A stochastic analysis suggested that there was more than a 90% probability that Peeling would be cost-effective at a willingness-to-pay threshold of £20,000 per QALY. Although there is no evidence of a statistically significant difference in either costs or QALYs between macular hole surgery with or without ILM peeling, the balance of probabilities is that ILM Peeling is likely to be a cost-effective option for the treatment of macular holes. Further long-term follow-up data are needed to confirm these findings.

  15. Inertial and stick-slip regimes of unstable adhesive tape peeling.

    PubMed

    Dalbe, Marie-Julie; Villey, Richard; Ciccotti, Matteo; Santucci, Stéphane; Cortet, Pierre-Philippe; Vanel, Loïc

    2016-05-18

    We present an experimental characterization of the detachment front unstable dynamics observed during the peeling of pressure sensitive adhesives. We use an experimental set-up specifically designed to control the peeling angle θ and the peeled tape length L, while peeling an adhesive tape from a flat substrate at a constant driving velocity V. High-speed imaging allows us to report the evolution of the period and amplitude of the front oscillations, as well as the relative durations of their fast and slow phases, as a function of the control parameters V, L and θ. Our study shows that, as the driving velocity or the peeling angle increases, the oscillations of the peeling front progressively evolve from genuine "stick-slip" oscillations, made of alternating long stick phases and very brief slip phases, to sinusoidal oscillations of amplitude twice the peeling velocity. We propose a model which, taking into account the peeling angle-dependent kinetic energy cost to accelerate and decelerate the peeled tape, explains the transition from the "stick-slip" to the "inertial" regime of the dynamical instability. Using independent direct measurements of the effective fracture energy of the adhesive-substrate joint, we show that our model quantitatively accounts for the two regimes of the unstable dynamics.

  16. Combination Superficial Peels With Salicylic Acid and Post-Peel Retinoids.

    PubMed

    Kligman, Douglas E; Draelos, Zoe D

    2016-04-01

    Salicylic acid (SA) and retinoids, tretinoin (all-trans retinoic acid [ATRA]), and retinol (all-trans retinol) are widely used as topical agents for the improvement of photodamage and acne vulgaris. They can be used in daily take-home products or as part of an in-office procedure, combining the benefits of a keratolytic (SA) and a retinoid. The objective of this research was to compare the efficacy for ameliorating photodamage of topical tretinoin (0.25%) and retinol (0.25%) to baseline and with each other when applied after a 30% salicylic acid peel on human facial skin. Twenty female subjects received a full face 30% SA peel followed by the overnight application of tretinoin to a 1 randomized half-face and retinol to the opposite side (split-face study). The identical procedure was repeated at week 2. Double-blinded subject and investigator assessments of the results were captured at weeks 2 and 4. By investigator evaluation, both peeling regimens were effective in improving photodamage parameters compared to baseline. (ATRA P-values at week 4 were: P=.00008 texture, P=.00013 roughness, P=.00221 pores, P=.00098 dryness, P=.02770 erythema, and P=.00008 overall appearance. Retinol P-values at week 4 were: P=.00019 texture, P=.00053 roughness, P=.00221 pores, P=.00147 dryness, P=.02770 erythema, and P=.0043 overall appearance.) By subject self-assessment compared with baseline, both tretinoin and retinol were effective in improving overall appearance (ATRA P=.0229 and retinol P=.0190). By investigator evaluation comparing tretinoin with retinol, tretinoin was slightly better than retinol at week 4 in improving texture P=.00506, roughness P=.01171, and overall appearance P=.00506. By subject self-assessment comparing tretinoin with retinol, there was no difference in overall appearance (ATRA P=.2367 and retinol P=.3613). Either topical tretinoin (0.25%) or retinol (0.25%) can be used safely and effectively when applied in office immediately after SA peeling to

  17. Ultrastructural observations of chemical peeling for skin rejuvenation (ultrastructural changes of the skin due to chemical peeling).

    PubMed

    Omi, Tokuya; Sato, Shigeru; Numano, Kayoko; Kawana, Seiji

    2010-02-01

    Chemical peeling of the skin is commonly used as a means to treat photoaging, but the mechanism underlying its efficacy has not yet been fully clarified. We recently conducted chemical peeling of the skin with glycolic acid and lactic acid and observed it at the ultrastructural level. No changes in the horny layer or the upper epidermal layer were observed but there was dissociation and vacuolation between the basal cells and increases in vimentin filaments within fibroblasts and endothelial cells were seen. These findings suggest that chemical peeling of the skin with this type of agent directly induces collagen formation within the dermis and thus directly stimulates remodeling of the dermis.

  18. Ultrasound treated potato peel and sweet lime pomace based biopolymer film development.

    PubMed

    Borah, Purba Prasad; Das, Pulak; Badwaik, Laxmikant S

    2017-05-01

    Treatment and management of food processing waste is a major challenge for food industry. Potato processing industry generates tremendous amount of peel and consider it as zero valued waste. Again, pomace generated after juice extraction from sweet lime pulp is considered as waste and not properly utilized. Whereas these waste could be utilized for the development of biodegradable packaging film to overcome environmental issues. Composite films were prepared with varying proportion of potato peel powder (PP) and sweet lime pomace (SLP) in the ratio of 0:1(A), 0.5:1(B), 1:1(C), 1:0.5(D), 1:0(E) with an ultrasound treatment of 45min, and 0:1(F), 0.5:1(G), 1:1(H), 1:0.5(I), 1:0(J) with an ultrasound treatment of 60min. Ultrasound was applied for 45 and 60min to film forming solutions to break down biopolymer particles small enough to form a film. All the films were analyzed for their barrier and mechanical properties. It was observed that increasing ultrasound treatment times gives better result in film properties and less PP content also gives better film properties, from these observations film G prepared with 0.5:1 (PP:SLP) showed better characteristics among all other films. Water vapor permeability, moisture absorption, water solubility, breakage strength and elongation capacity of G film were reported as 7.25×10 -9 g/Pahm, 12.88±0.348%, 38.92±0.702%, 242.01±3.074g and 7.61±0.824mm respectively. However, thermal decomposition for film G took place above 200°C. The film forming solution of selected G film, added with clove essential oil (1.5%) as an antimicrobial agent was wrapped on bread and stored it for 5days. The film was successful in lowering the weight loss, reducing the hardness and inhibition of surface microbial load from bread sample. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Comparative study of 15% TCA peel versus 35% glycolic acid peel for the treatment of melasma

    PubMed Central

    Puri, Neerja

    2012-01-01

    Background: Chemical peels are the mainstay of a cosmetic practitioner's armamentarium because they can be used to treat some skin disorders and can provide aesthetic benefit. Objectives: To compare 15% TCA peel and 35% glycolic acid peel for the treatment of melasma. Material and Methods: We selected 30 participants of melasma aged between 20 and 50 years from the dermatology outpatient department and treated equal numbers with 15% TCA and 35% glycolic acid. Results: Subjective response as graded by the patient showed good or very good response in 70% participants in the glycolic acid group and 64% in the TCA group. Conclusions: There was statistically insignificant difference in the efficacy between the two groups for the treatment of melasma. PMID:23130283

  20. Acral peeling skin syndrome in two East-African siblings: case report.

    PubMed

    Kiprono, Samson K; Chaula, Baraka M; Naafs, Bernard; Masenga, John E

    2012-03-19

    Acral peeling skin syndrome is a rare autosomal recessive genodermatosis due to a missense mutation in transglutaminase 5. The skin peeling occurs at the separation of the stratum corneum from the stratum granulosum. We present a case of two siblings who developed continuous peeling of the palms and soles from the first year of life. This peeling was more severe on the soles than palms and on younger sibling than elder sibling. Peeling is worsened by occlusion and sweating. Sporadic cases of Acral Peeling Skin Syndrome occur in African population. There is variability in time of presentation and clinical severity even within families.

  1. Complications of Macular Peeling

    PubMed Central

    Asencio-Duran, Mónica; Manzano-Muñoz, Beatriz; Vallejo-García, José Luis; García-Martínez, Jesús

    2015-01-01

    Macular peeling refers to the surgical technique for the removal of preretinal tissue or the internal limiting membrane (ILM) in the macula for several retinal disorders, ranging from epiretinal membranes (primary or secondary to diabetic retinopathy, retinal detachment…) to full-thickness macular holes, macular edema, foveal retinoschisis, and others. The technique has evolved in the last two decades, and the different instrumentations and adjuncts have progressively advanced turning into a safer, easier, and more useful tool for the vitreoretinal surgeon. Here, we describe the main milestones of macular peeling, drawing attention to its associated complications. PMID:26425351

  2. Effect of chemical peeling on the skin in relation to UV irradiation.

    PubMed

    Funasaka, Yoko; Abdel-Daim, Mohamed; Kawana, Seiji; Nishigori, Chikako

    2012-07-01

    Chemical peeling is one of the dermatological treatments available for certain cutaneous diseases and conditions or improvement of cosmetic appearance of photoaged skin. However, it needs to be clarified whether the repetitive procedure of chemical peeling on photodamaged skin is safe and whether the different chemicals used for peeling results in similar outcomes or not. In this article, we reviewed the effect of peeling or peeling agents on the skin in relation to ultraviolet (UV) radiation. The pretreatment of peeling agents usually enhance UV sensitivity by inducing increased sunburn cell formation, lowering minimum erythematous dose and increasing cyclobutane pyrimidine dimers. However, this sensitivity is reversible and recovers to normal after 1-week discontinuation. Using animals, the chronic effect of peeling and peeling agents was shown to prevent photocarcinogenesis. There is also an in vitro study using culture cells to know the detailed mechanisms of peeling agents, especially on cell proliferation and apoptotic changes via activating signalling cascades and oxidative stress. It is important to understand the effect of peeling agents on photoaged skin and to know how to deal with UV irradiation during the application of peeling agents and treatment of chemical peeling in daily life. © 2012 John Wiley & Sons A/S.

  3. Extraction of orange peel's essential oil by solvent-free microwave extraction

    NASA Astrophysics Data System (ADS)

    Qadariyah, Lailatul; Amelia, Prilia Dwi; Admiralia, Cininta; Bhuana, Donny S.; Mahfud, Mahfud

    2017-05-01

    Sweet orange peel (Citrus sinensis) is part of orange plant that contains essential oils. Generally, taking essential oil from orange peel is still using hydrodistillation and steam-hydrodistillation method which still needs solvent and takes a long time to produce high quality essential oil. Therefore, the objectives of this experiment are to study the process of orange peel's essential oil extraction using Solvent Free Microwave Extraction (SFME) and to study the operating condition that effect an optimum yield and quality of the essential oil. In this experiment, extraction process with SFME method goes for 60 minutes at atmospheric pressure. Variables for SFME are: variation of orange peel condition (fresh and dry), ratio orange peel mass to distiller volume (0,1; 0,2; 0,3; 0,4 g/mL), orange peel size (±0,5; ±2; ±3,5 cm width), and microwave power (100, 264, 400 Watt). Moisture content of fresh peel is 71,4% and for dry peel is 17,37% which is obtained by sun drying. The result of this experiment will be analyzed with GC-MS, SEM, density, and miscibility in ethanol 90%. The optimum result obtained from this experiment based on the number of the yield under condition of fresh orange peel is at peel mass/distiller volume 0,1 g/mL, orange peel size ±3,5 cm width, and microwave power 400 Watt, results 1,6738% yield. The result of GC-MS for fresh orange peel shows that the dominant compound is Limonene 54,140% and for dry orange peel is Limonene 59,705%. The density obtained is around 0,8282-0,8530 g/mL and miscibility in ethanol 90% is 1:5.

  4. Epidemiology of Usher syndrome in Valencia and Spain.

    PubMed

    Espinós, C; Millán, J M; Beneyto, M; Nájera, C

    1998-01-01

    To obtain epidemiological data on the prevalence of the different types of Usher syndrome (US) in Spain, since these data were missing; to estimate the proportion of sporadic cases among simplex families, and calculate the prevalence of the Usher syndrome in a homogeneous population from Eastern Spain (3,875,234 inhabitants) that is representative of the Spanish population. Otological, ophthalmological and genetic studies were performed in 89 US patients from 46 families and subjected to statistical and segregation analysis. 41.6% of them suffered US type I, 46.1% type II, and in 12.3% the classification remains unclear. The estimated prevalence for the Province of Valencia was 4.2/100,000. There was a notable excess of male-only affected multiplex sibships in our sample that could be attributable to an X-linked inheritance. The number of families with USI type was similar to that of families with USII type. The estimated prevalence for the Province of Valencia is in agreement with other reports in which the estimate for the prevalence of US ranges from 1.8 to 6.2/100,000.

  5. Phenolic profile and antioxidant activity from peels and seeds of melon (Cucumis melo L. var. reticulatus) and their antiproliferative effect in cancer cells.

    PubMed

    Rolim, P M; Fidelis, G P; Padilha, C E A; Santos, E S; Rocha, H A O; Macedo, G R

    2018-03-01

    Melon (Cucumis melo L.) has high economic value and in recent years, its production has increased; however, part of the fruit is wasted. Usually, inedible parts such as peel and seeds are discarded during processing and consumption. Extracts of melon residues were prepared and their phenolic compounds, antioxidants and antiproliferative activities were evaluated. Total phenolic compounds were found in hydroethanolic, hydromethanolic, and aqueous extracts, especially for melon peel (1.016 mg gallic acid equivalent/100 g). Flavonoids total content found for melon peel aqueous extract was 262 µg of catechin equivalent (CA)/100 g. In all extracts of melon peel significant amounts of gallic acid, catechin, and eugenol were found. For total antioxidant capacity, reported as ascorbic acid equivalent, the hydroethanolic and hydromethanolic extracts in peels and hydromethanolic in seeds were 89, 74, and 83 mg/g, respectively. Different extracts of melon showed iron and copper ions chelating activity at different concentrations, especially melon peel aqueous extract, reaching values of 61% for iron and 84% for copper. The hydroethanolic extract of melon peel presented a significant ability for hydroxyl radicals scavenging (68%). To assess the antiproliferative potential in human cancer cell lines, such as kidney carcinoma, colorectal carcinoma, cervical adenocarcinoma and cervical carcinoma, MTT assay was performed. The proliferation was inhibited by 20-85% at extracts concentrations of 0.1-1.0 mg/mL in all cancer cell lines. The results suggest that melon residues extracts display a high antioxidant activity in in vitro assays and have effective biological activity against the growth of human tumor cells.

  6. Phenolic profile and antioxidant activity from peels and seeds of melon (Cucumis melo L. var. reticulatus) and their antiproliferative effect in cancer cells

    PubMed Central

    Rolim, P.M.; Fidelis, G.P.; Padilha, C.E.A.; Santos, E.S.; Rocha, H.A.O.; Macedo, G.R.

    2018-01-01

    Melon (Cucumis melo L.) has high economic value and in recent years, its production has increased; however, part of the fruit is wasted. Usually, inedible parts such as peel and seeds are discarded during processing and consumption. Extracts of melon residues were prepared and their phenolic compounds, antioxidants and antiproliferative activities were evaluated. Total phenolic compounds were found in hydroethanolic, hydromethanolic, and aqueous extracts, especially for melon peel (1.016 mg gallic acid equivalent/100 g). Flavonoids total content found for melon peel aqueous extract was 262 µg of catechin equivalent (CA)/100 g. In all extracts of melon peel significant amounts of gallic acid, catechin, and eugenol were found. For total antioxidant capacity, reported as ascorbic acid equivalent, the hydroethanolic and hydromethanolic extracts in peels and hydromethanolic in seeds were 89, 74, and 83 mg/g, respectively. Different extracts of melon showed iron and copper ions chelating activity at different concentrations, especially melon peel aqueous extract, reaching values of 61% for iron and 84% for copper. The hydroethanolic extract of melon peel presented a significant ability for hydroxyl radicals scavenging (68%). To assess the antiproliferative potential in human cancer cell lines, such as kidney carcinoma, colorectal carcinoma, cervical adenocarcinoma and cervical carcinoma, MTT assay was performed. The proliferation was inhibited by 20–85% at extracts concentrations of 0.1–1.0 mg/mL in all cancer cell lines. The results suggest that melon residues extracts display a high antioxidant activity in in vitro assays and have effective biological activity against the growth of human tumor cells. PMID:29513789

  7. Randomized trial comparing a chemical peel containing a lipophilic hydroxy acid derivative of salicylic acid with a salicylic acid peel in subjects with comedonal acne.

    PubMed

    Levesque, Annie; Hamzavi, Iltefat; Seite, Sophie; Rougier, André; Bissonnette, Robert

    2011-09-01

    Lipohydroxyacid is a lipophilic derivative of salicylic acid with comedolytic properties. To compare lipohydroxyacid and salicylic acid peels in subjects with comedonal acne. In this split face, randomized study, 20 subjects with comedonal acne received lipohydroxyacid peels on one side of the face, while the other side was treated with salicylic acid peels. A total of six peels at 2-week intervals were performed. Efficacy was evaluated by counting noninflammatory and inflammatory lesions and by performing a global change in acne assessment. Safety was assessed by evaluating adverse events, global tolerance, and the presence of erythema, scaling, and dryness. There was a statistically significant decrease of 55.6% and 48.5% from baseline to Day 98 in the mean number of noninflammatory lesions for the sides treated with lipohydroxyacid and salicylic acid peels, respectively (P < 0.001). There was no significant difference in the degree of reduction in noninflammatory lesions between the two peels. There was no significant reduction in the number of inflammatory lesions. Both peels were generally very well tolerated. This study suggests that lipohydroxyacid peels can be beneficial to subjects with comedonal acne. © 2011 Wiley Periodicals, Inc.

  8. Three-dimensional hierarchical and interconnected honeycomb-like porous carbon derived from pomelo peel for high performance supercapacitors

    NASA Astrophysics Data System (ADS)

    Liu, Jingyuan; Li, Hongpeng; Zhang, Hongsen; Liu, Qi; Li, Rumin; Li, Bin; Wang, Jun

    2018-01-01

    The urgent need for sustainable development of human society has forced material scientists to explore novel materials starting from cheap natural precursors for next-generation energy storage devices by using environmentally friendly strategies. In this work, heteroatom-functionalized porous carbonaceous materials with 3D hierarchical and interconnected honeycomb-like structure have been successfully synthesized by using waste biomass pomelo peel as raw material through the combination of hydrothermal carbonization and followed KOH activation procedure. Benefiting from the unique honeycomb-like structure and high specific surface area, the as-obtained carbon material exhibits satisfactory capacitive behavior: 374 F/g at 0.1 A/g; excellent cycling stability of 92.5% capacitance retention over continuous 5000 cycles. More importantly, the as-assembled symmetric supercapacitors based on as-prepared electrode material can deliver high gravimetric and volumetric energy density of 20 W h/kg and 18.7 W h/L in 6 M KOH, respectively, as well as outstanding cycling stability. The obtained results demonstrate the possibility for taking full advantage of sustainable and large scale advanced carbon materials by choosing waste biomass, particularly the pomelo peel as a raw material.

  9. Production of single cell protein from agro-waste using Rhodococcus opacus.

    PubMed

    Mahan, Kristina M; Le, Rosemary K; Wells, Tyrone; Anderson, Seth; Yuan, Joshua S; Stoklosa, Ryan J; Bhalla, Aditya; Hodge, David B; Ragauskas, Arthur J

    2018-06-18

    Livestock and fish farming are rapidly growing industries facing the simultaneous pressure of increasing production demands and limited protein required to produce feed. Bacteria that can convert low-value non-food waste streams into singe cell protein (SCP) present an intriguing route for rapid protein production. The oleaginous bacterium Rhodococcus opacus serves as a model organism for understanding microbial lipid production. SCP production has not been explored using an organism from this genus. In the present research, R. opacus strains DSM 1069 and PD630 were fed three agro-waste streams: (1) orange pulp, juice, and peel; (2) lemon pulp, juice, and peel; and (3) corn stover effluent, to determine if these low-cost substrates would be suitable for producing a value-added product, SCP for aquafarming or livestock feed. Both strains used agro-waste carbon sources as a growth substrate to produce protein-rich cell biomass suggesting that that R. opacus can be used to produce SCP using agro-wastes as low-cost substrates.

  10. Whitening effect of salicylic acid peels in Asian patients.

    PubMed

    Ahn, Hyo Hyun; Kim, Il-hwan

    2006-03-01

    Patients with skin of color demand treatment modality suitable for their skin. Salicylic acid peel has effectiveness for both of acne and postinflammatory hyperpigmentation that are common in patients with skin of color. To assess the whitening effect of salicylic acid peels in Asian patients with acne objectively by the colorimetric method. Twenty-four healthy adult patients with acne participated voluntarily in the study. Any other systemic and topical acne treatments were prohibited. They had undergone full-face peels with 30% salicylic acid in absolute ethanol bi-weekly for 3 months. Colorimetric changes of the face were recorded with reflectance spectrophotometer. Paired comparisons with pretreatment CIE L*a*b* showed abrupt descent of L* value after first peel (p=.0286). Then there was continued increase of mean L* value, even though the final L* value did not reach a statistically significant level. The mean a* value decreased continually, and the a* values recorded after the second, third, fourth, fifth, and final peel showed significantly lowered levels (p=.0027, .0005, <.0001, <.0001, <.0001). Salicylic acid peels are beneficial in whitening the face of Asian patients with acne. The whitening effect would be an important factor in choosing the superficial peeling agent for them.

  11. INTERNAL LIMITING MEMBRANE PEELING IN MACULAR HOLE SURGERY; WHY, WHEN, AND HOW?

    PubMed

    Chatziralli, Irini P; Theodossiadis, Panagiotis G; Steel, David H W

    2018-05-01

    To review the current rationale for internal limiting membrane (ILM) peeling in macular hole (MH) surgery and to discuss the evidence base behind why, when, and how surgeons peel the ILM. Review of the current literature. Pars plana vitrectomy is an effective treatment for idiopathic MH, and peeling of the ILM has been shown to improve closure rates and to prevent postoperative reopening. However, some authors argue against ILM peeling because it results in a number of changes in retinal structure and function and may not be necessary in all cases. Furthermore, the extent of ILM peeling optimally performed and the most favorable techniques to remove the ILM are uncertain. Several technique variations including ILM flaps, ILM scraping, and foveal sparing ILM peeling have been described as alternatives to conventional peeling in specific clinical scenarios. Internal limiting membrane peeling improves MH closure rates but can have several consequences on retinal structure and function. Adjuvants to aid peeling, instrumentation, technique, and experience may all alter the outcome. Hole size and other variables are important in assessing the requirement for peeling and potentially its extent. A variety of evolving alternatives to conventional peeling may improve outcomes and need further study.

  12. Recovery of Ga(III) by Raw and Alkali Treated Citrus limetta Peels

    PubMed Central

    2014-01-01

    Alkali treated Citrus limetta peels were used for recovery of Ga(III) from its aqueous solution. The raw and alkali treated peels were characterized for functional groups. The efficiency of adsorption increased from 47.62 mg/g for raw peels to 83.33 mg/g for alkali treated peels. Between pH 1 and 3, the adsorption increased and thereafter decreased drastically. The adsorption followed pseudosecond order kinetics and Langmuir isotherm gave the best fit for the experimental data. Desorption studies showed 95.28% desorption after 3 cycles for raw peels while it was 89.51% for alkali treated peels. Simulated Bayer liquor showed 39.57% adsorption for gallium ions on raw peels which was enhanced to 41.13% for alkali treated peels. PMID:27382624

  13. Comparison of waste pumpkin material and its potential use in extruded snack foods.

    PubMed

    Norfezah, M N; Hardacre, A; Brennan, C S

    2011-08-01

    Material was produced from Crown pumpkin (Cucurbita maxima) processed from fractions of the fruit which are regarded as waste stream products (peel, flesh and seed). The flour from the three different fractions (peel, flesh and seed) of Crown pumpkin flour was incorporated into an extruded snack product formulation at levels 10%, 30% and 50% (w/w with corn grit) and processed in a twin-screw extruder to make 10 expanded snack products. Proximate analysis was carried out to determine the nutritional value of the raw pumpkin and pumpkin flour. A physical analysis of the product was used to determine its color, the expansion ratio, bulk density and texture. Inclusion of waste stream material (peel and seed) at 10%, yielded extruded products with similar expansion and density characteristics to the control sample; however, an inclusion of greater than 10% yielded significant challenges to product quality (hardness of the product).

  14. Acral peeling skin syndrome in two East-African siblings: case report

    PubMed Central

    2012-01-01

    Background Acral peeling skin syndrome is a rare autosomal recessive genodermatosis due to a missense mutation in transglutaminase 5. The skin peeling occurs at the separation of the stratum corneum from the stratum granulosum. Case presentation We present a case of two siblings who developed continuous peeling of the palms and soles from the first year of life. This peeling was more severe on the soles than palms and on younger sibling than elder sibling. Peeling is worsened by occlusion and sweating. Conclusions Sporadic cases of Acral Peeling Skin Syndrome occur in African population. There is variability in time of presentation and clinical severity even within families. PMID:22429841

  15. Fovea sparing internal limiting membrane peeling using multiple parafoveal curvilinear peels for myopic foveoschisis: technique and outcome.

    PubMed

    Jin, Haiying; Zhang, Qi; Zhao, Peiquan

    2016-10-18

    To introduce a modified surgical technique, the "parafoveal multiple curvelinear internal limiting membrane (ILM) peeling", to preserve epi-foveal ILM in myopic foveoschisis surgery. Consecutive patients with myopic foveoschisis were enrolled in the present prospective interventional case series. The surgeries were performed using transconjunctival 23-gauge system. The macular area was divided into quadrants. ILM was peeled off in a curvilinear manner centered around the site that was away from the central fovea in each quadrant. Shearing forces were used to control the direction to keep the peeling away from central fovea. ILM at central fovea of about 500 to 1000 μm was preserved by this technique. This technique was performed in 20 eyes of 20 consecutive patients. Epi-foveal ILM was successfully preserved in all cases using the technique. Patients were followed up for more than 12 months. The mean postoperative logMAR visual acuity improved from 1.67 ± 0.65 preoperatively to 1.15 ± 0.49 (P = 0.015; paired t-test). Postoperative OCT examinations showed that full-thickness macular holes (MHs) did not developed in any case. Central fovea thickness decreased from 910 ± 261 μm preoperatively to 125 ± 85 postoperatively (P = 0.001; paired t-test). Fovea sparing ILM peeling using multiple parafoveal curvilinear peels prevents the development of postoperative full-thickness MHs in eyes with myopic foveoschisis.

  16. Salicylic acid as a peeling agent: a comprehensive review

    PubMed Central

    Arif, Tasleem

    2015-01-01

    Salicylic acid has been used to treat various skin disorders for more than 2,000 years. The ability of salicylic acid to exfoliate the stratum corneum makes it a good agent for peeling. In particular, the comedolytic property of salicylic acid makes it a useful peeling agent for patients with acne. Once considered as a keratolytic agent, the role of salicylic acid as a desmolytic agent, because of its ability to disrupt cellular junctions rather than breaking or lysing intercellular keratin filaments, is now recognized and is discussed here. Salicylic acid as a peeling agent has a number of indications, including acne vulgaris, melasma, photodamage, freckles, and lentigines. The efficacy and safety of salicylic acid peeling in Fitzpatrick skin types I–III as well as in skin types V and VI have been well documented in the literature. This paper reviews the available data and literature on salicylic acid as a peeling agent and its possible indications. Its properties, efficacy and safety, the peeling procedure, and possible side effects are discussed in detail. An account of salicylism is also included. PMID:26347269

  17. Salicylic acid as a peeling agent: a comprehensive review.

    PubMed

    Arif, Tasleem

    2015-01-01

    Salicylic acid has been used to treat various skin disorders for more than 2,000 years. The ability of salicylic acid to exfoliate the stratum corneum makes it a good agent for peeling. In particular, the comedolytic property of salicylic acid makes it a useful peeling agent for patients with acne. Once considered as a keratolytic agent, the role of salicylic acid as a desmolytic agent, because of its ability to disrupt cellular junctions rather than breaking or lysing intercellular keratin filaments, is now recognized and is discussed here. Salicylic acid as a peeling agent has a number of indications, including acne vulgaris, melasma, photodamage, freckles, and lentigines. The efficacy and safety of salicylic acid peeling in Fitzpatrick skin types I-III as well as in skin types V and VI have been well documented in the literature. This paper reviews the available data and literature on salicylic acid as a peeling agent and its possible indications. Its properties, efficacy and safety, the peeling procedure, and possible side effects are discussed in detail. An account of salicylism is also included.

  18. In vitro interactions with repeated grapefruit juice administration--to peel or not to peel?

    PubMed

    Brill, Shlomo; Zimmermann, Christian; Berger, Karin; Drewe, Juergen; Gutmann, Heike

    2009-03-01

    Interactions of acutely administered grapefruit juice (GFJ) with cytochrome P450 isoform 3A4 (CYP3A4) and P-glycoprotein (Pgp) function are well established. In this study, we investigated in vitro the effect of repeated administration of GFJ and its major constituents (the flavonoid naringin, its aglycone naringenin and the furanocoumarin bergamottin) on mRNA expression of MDR1 and CYP3A4 in LS180 cells. Since the bergamottin content is higher in the peel than in the fruit, we compared GFJ containing peel (GFJP+) with juice without any peel extract (GFJP-). GFJP- (1%) showed no significant effect on MDR1 and CYP3A4 mRNA expression, whereas 1% GFJP+ increased expression of MDR1 3.7-fold (P<0.01) and CYP3A4 2.3-fold (P<0.05). Of the tested constituents, only 10 microM bergamottin and 200 microM naringenin induced MDR1 mRNA levels 2.9- and 4.0-fold, respectively (P<0.01 for both), and CYP3A4 mRNA levels 3.2- and 15.6-fold (P<0.01 for both), respectively. Western blot analysis and rhodamine 123 uptake experiments partly confirmed these findings on the protein and the functional level. In summary, GFJ containing no peel extract may have a lower potential for interactions with CYP3A4 or P-glycoprotein.

  19. Vitrectomy with internal limiting membrane (ILM) peeling versus vitrectomy with no peeling for idiopathic full-thickness macular hole (FTMH).

    PubMed

    Spiteri Cornish, Kurt; Lois, Noemi; Scott, Neil; Burr, Jennifer; Cook, Jonathan; Boachie, Charles; Tadayoni, Ramin; la Cour, Morten; Christensen, Ulrik; Kwok, Alvin

    2013-06-05

    Several observational studies have suggested the potential benefit of internal limiting membrane (ILM) peeling to treat idiopathic full-thickness macular hole (FTMH). However, no strong evidence is available on the potential benefit(s) of this surgical manoeuvre and uncertainty remains among vitreoretinal surgeons about the indication for peeling the ILM, whether to use it in all cases or in long-standing and/or larger holes.  To determine whether ILM peeling improves anatomical and functional outcomes of macular hole surgery compared with the no-peeling technique and to investigate the impact of different parameters such as presenting vision, stage/size of the hole and duration of symptoms in the success of the surgery. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) which contains the Cochrane Eyes and Vision Group Trials Register (The Cochrane Library 2013, Issue 2), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE, (January 1950 to February 2013), EMBASE (January 1980 to February 2013), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to February 2013), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We searched the reference lists of included studies for any additional studies not identified by the electronic searches. We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 28 February 2013.We searched reference lists of the studies included in the review for information about other studies on ILM peeling in macular hole surgery. We searched Proceedings for the following conferences up to February 2013: American Academy of Ophthalmology (AAO), Annual Meeting of the American Society of Retina Specialists

  20. Guidelines for chemical peeling in Japan (3rd edition).

    PubMed

    2012-04-01

    Chemical peeling may be defined as the therapies, procedures and techniques used for the treatment of certain cutaneous diseases or conditions, and for aesthetic improvement. The procedures include the application of one or more chemical agents to the skin. Chemical peeling has been very popular in both medical and aesthetic fields. Because neither its scientific background is well understood nor a systematic approach established, medical and social problems have taken place. This prompted us to establish and distribute a standard guideline of care for chemical peeling. Previous guidelines such as the 2001 and 2004 versions included minimum standards of care such as indications, chemicals, applications, and any associated precautions, including post-peeling care. The principles in this updated version of chemical peeling are as follows: (i) chemical peeling should be performed under the strict technical control and responsibility of a physician; (ii) the physician should have sufficient knowledge of the structure and physiology of the skin and subcutaneous tissues, and understand the mechanisms of wound-healing induced by chemical peeling; (iii) the physician should be board-certified in an appropriate specialty such as dermatology; and (iv) the ultimate judgment regarding the appropriateness of any specific chemical peeling procedure must be made by the physician while considering all standard therapeutic protocols, which should be presented to each individual patient. Keeping these concepts in mind, this new version of the guidelines includes a more scientific and detailed approach from the viewpoint of evidence-based medicine. © 2011 Japanese Dermatological Association.

  1. Understanding Surface Adhesion in Nature: A Peeling Model.

    PubMed

    Gu, Zhen; Li, Siheng; Zhang, Feilong; Wang, Shutao

    2016-07-01

    Nature often exhibits various interesting and unique adhesive surfaces. The attempt to understand the natural adhesion phenomena can continuously guide the design of artificial adhesive surfaces by proposing simplified models of surface adhesion. Among those models, a peeling model can often effectively reflect the adhesive property between two surfaces during their attachment and detachment processes. In the context, this review summarizes the recent advances about the peeling model in understanding unique adhesive properties on natural and artificial surfaces. It mainly includes four parts: a brief introduction to natural surface adhesion, the theoretical basis and progress of the peeling model, application of the peeling model, and finally, conclusions. It is believed that this review is helpful to various fields, such as surface engineering, biomedicine, microelectronics, and so on.

  2. Testicular histology and blood testosterone levels of male rabbit after given concentrated diets containing calliandra leaf meal and pineapple peels

    NASA Astrophysics Data System (ADS)

    Setyawati, I.; Ermayanti, N. G. A. M.; Suarni, N. M. R.; Narayani, I.; Suaskara, I. B. M.

    2018-03-01

    Calliandra calothyrsus Meissn is one of a highly protein source of forage, however, it is not widely used for non ruminant feed because it contains antinutritional substances in the form of condensed tannin. Tannin can bind proteins, this tannin-protein complexes are difficult to be digested in the gastrointestinal tract, then will be defecated outside the body. To optimize the utilization of calliandra in the diet, pineapple peels were added as a source of protease (bromelain). Beside of waste utilization, it is expected that bromelain can degrade the tannin-protein complexes thereby reducing the negative effects of tannins. This research is a feeding experiment on male rabbit (Lepus sp), five weeks old. The diet formulation is prepared according to the standardized diet of the local rabbit. This experiment used a Completely Randomized Design (CRD) with four treatments i.e. control group which were only given commercial feed (R0), commercial feed contained 15% of Calliandra leaf meal and 30% of pineapple peel (R1), commercial feed contained 30% of Calliandra leaf meal and 30% of pineapple peel (R2), and commercial feed contained 45% of Calliandra and 30% of pineapple peel (R3). The treatment was done for three months. The results of this study on the reproduction of male rabbits showed that the increase of calliandra leaf meal level in a diet containing 30% of pineapple peels affected the testicular histology, and also decreased the diameter of seminiferous tubule and blood testosterone levels of male rabbits.

  3. Biohydrogen Production from Pineapple Waste: Effect of Substrate Concentration and Acid Pretreatment

    NASA Astrophysics Data System (ADS)

    Cahyari, K.; Putri, A. M.; Oktaviani, E. D.; Hidayat, M. A.; Norajsha, J. D.

    2018-05-01

    Biohydrogen is the ultimate choice of energy carrier in future due to its superior qualities such as fewer greenhouse gases emission, high energy density (142 kJ/gram), and high energy conversion using a fuel cell. Production of biohydrogen from organic waste e.g. pineapple waste offers a simultaneous solution for renewable energy production and waste management. It is estimated that pineapple cultivation in Indonesia generated more than 1 million ton/year comprising of rotten pineapple fruit, leaves, and stems. Majority of this waste is dumped into landfill area without any treatments which lead to many environmental problems. This research was meant to investigate the utilization of pineapple waste i.e. peel and the core of pineapple fruit and leaves to produce biohydrogen through mesophilic dark fermentation (30°C, 1 atm, pH 5.0). Effect of dilute acid treatment and substrate concentration was particularly investigated in these experiments. Peel and core of pineapple waste were subjected to fermentation at 3 various substrate concentration i.e. 8.8, 17.6 and 26.4-gram VS/liter. Meanwhile, pineapple leaves were pretreated using dilute acid (H2SO4) at 0.2, 0.3 and 0.4 N and followed by dark fermentation. Results show that the highest yield of biohydrogen was obtained at a substrate concentration of 26.4-gram VS/liter both for peel and core of the waste. Pretreatment using dilute acid (H2SO4) 0.3 N might improve fermentation process with a higher yield at 0.8 ml/gram VS. Hydrogen percentage in biogas produced during fermentation process was in the range between 5 – 32% of volume ratio. In summary, it is possible to utilize pineapple waste for production of biohydrogen at an optimum substrate concentration of 26.4-gram VS/liter and acid pretreatment (H2SO4) of 0.3 N.

  4. Palmoplantar peeling secondary to sirolimus therapy.

    PubMed

    Liu, L S; McNiff, J M; Colegio, O R

    2014-01-01

    Sirolimus (rapamycin) is an immunosuppressive agent commonly used in transplant recipients. Although sirolimus has less renal toxicity than calcineurin inhibitors, its use has been limited by its side effects. The most common cutaneous pathologies associated with sirolimus are inflammatory acneiform eruptions, lymphedema and aphthous ulcers. We present a novel cutaneous manifestation of sirolimus therapy that limited its use in at least one transplant recipient. Upon commencing sirolimus therapy, four solid organ transplant recipients developed tender, nonpruritic palmoplantar peeling within the first month of therapy. The peeling clinically resembled a mild form of hand-foot syndrome, yet none of the patients had been treated with chemotherapeutics. Desquamation presented on the palms and soles with dry vesicles and minor peeling extending to the dorsal aspects of the hands and feet. Histologically, the lesions were noninflammatory; the epidermis showed subtle separation between keratinocytes, suggesting either spongiosis or a defect in intercellular adhesion. One patient opted to discontinue treatment because of the tenderness associated with the palmoplantar peeling, which resulted in complete resolution within 2 weeks. © Copyright 2013 The American Society of Transplantation and the American Society of Transplant Surgeons.

  5. Differential partitioning of triterpenes and triterpene esters in apple peel

    USDA-ARS?s Scientific Manuscript database

    Apple peel functions as a protective barrier against biotic and abiotic stresses, and preserving the integrity and appearance of peel critical for market acceptance. Peel epidermal cells and epicuticular wax are a rich source of secondary metabolites, including triterpenes. Several studies have ou...

  6. Development of Infrared Radiation Heating Method for Sustainable Tomato Peeling

    USDA-ARS?s Scientific Manuscript database

    Although lye peeling is the widely industrialized method for producing high quality peeled fruit and vegetable products, the peeling method has resulted in negative impacts by significantly exerting both environmental and economic pressure on the tomato processing industry due to its associated sali...

  7. Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study.

    PubMed

    Garg, Vijay Kumar; Sinha, Surabhi; Sarkar, Rashmi

    2009-01-01

    Many clinicians have used glycolic acid (GA) peels for facial acne, scarring, and hyperpigmentation, mainly in lighter skin types. Salicylic-mandelic acid combination peels (SMPs) are a newer modality, and there have been no well-controlled studies comparing them with other conventional agents. To compare the therapeutic efficacy and tolerability of 35% GA peels and 20% salicylic-10% mandelic acid peels in active acne and post-acne scarring and hyperpigmentation. Forty-four patients with facial acne and post-acne scarring and hyperpigmentation were divided into two groups, with one receiving GA peels and the other SMPs at fortnightly intervals for six sessions. The treating physician performed objective evaluation of treatment outcomes. The patients, the treating physician, and an independent observer made subjective assessments. Side effects of both agents were also noted. Both the agents were effective, but SMPs had a higher efficacy for most active acne lesions (p<.001) and hyperpigmentation (p<.001). Side effects were also lesser with SMPs. Both the agents were effective and safe in Indian patients, with SMPs being better for active acne and post-acne hyperpigmentation.

  8. Understanding Surface Adhesion in Nature: A Peeling Model

    PubMed Central

    Gu, Zhen; Li, Siheng; Zhang, Feilong

    2016-01-01

    Nature often exhibits various interesting and unique adhesive surfaces. The attempt to understand the natural adhesion phenomena can continuously guide the design of artificial adhesive surfaces by proposing simplified models of surface adhesion. Among those models, a peeling model can often effectively reflect the adhesive property between two surfaces during their attachment and detachment processes. In the context, this review summarizes the recent advances about the peeling model in understanding unique adhesive properties on natural and artificial surfaces. It mainly includes four parts: a brief introduction to natural surface adhesion, the theoretical basis and progress of the peeling model, application of the peeling model, and finally, conclusions. It is believed that this review is helpful to various fields, such as surface engineering, biomedicine, microelectronics, and so on. PMID:27812476

  9. Biodegradable bioplastics from food wastes

    USDA-ARS?s Scientific Manuscript database

    An estimated 1.8 billion tons of waste are created annually from food processing in the US, including the peels, pulp, and pomace (PPP) generated from fruits and vegetables when they are converted into frozen or canned products or pressed into juice. PPP currently is sold as animal feed at low cost,...

  10. Cross-Validation of Survival Bump Hunting by Recursive Peeling Methods.

    PubMed

    Dazard, Jean-Eudes; Choe, Michael; LeBlanc, Michael; Rao, J Sunil

    2014-08-01

    We introduce a survival/risk bump hunting framework to build a bump hunting model with a possibly censored time-to-event type of response and to validate model estimates. First, we describe the use of adequate survival peeling criteria to build a survival/risk bump hunting model based on recursive peeling methods. Our method called "Patient Recursive Survival Peeling" is a rule-induction method that makes use of specific peeling criteria such as hazard ratio or log-rank statistics. Second, to validate our model estimates and improve survival prediction accuracy, we describe a resampling-based validation technique specifically designed for the joint task of decision rule making by recursive peeling (i.e. decision-box) and survival estimation. This alternative technique, called "combined" cross-validation is done by combining test samples over the cross-validation loops, a design allowing for bump hunting by recursive peeling in a survival setting. We provide empirical results showing the importance of cross-validation and replication.

  11. Differential Partitioning of Triterpenes and Triterpene Esters in Apple Peel.

    PubMed

    Poirier, Brenton C; Buchanan, David A; Rudell, David R; Mattheis, James P

    2018-02-28

    Apple peel is a rich source of secondary metabolites, and several studies have outlined the dietary health benefits of ursane-type triterpenes in apple. Changes in triterpene metabolism have also been associated with the development of superficial scald, a postharvest apple peel browning disorder, and postharvest applications of diphenylamine and 1-methylcyclopropene. Previously, studies have generated metabolite profiles for whole apple peel or apple wax. In this study, we report separate metabolic analyses of isolated wax fractions and peel epidermis to investigate the spatial distribution of secondary metabolites in peel. In addition to examining previously reported triterpenes, we identified several unreported fatty acid esters of ursane-type triterpenes (C14-C22). All free pentacyclic triterpenes and triterpenic acids, with the exception of β-amyrin, were localized in the wax layer, along with esters of ursolic acid and uvaol. All sterols, sterol derivatives and α-amyrin esters were localized in the dewaxed peel epidermis.

  12. Peeling the Onion: Why Centralized Control / Decentralized Execution Works

    DTIC Science & Technology

    2014-04-01

    March–April 2014 Air & Space Power Journal | 24 Feature Peeling the Onion Why Centralized Control / Decentralized Execution Works Lt Col Alan Docauer...DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Peeling the Onion : Why Centralized Control / Decentralized Execution Works 5a...Air & Space Power Journal | 25 Docauer Peeling the Onion Feature What Is Centralized Control / Decentralized Execution? Emerging in the aftermath of

  13. Use of cellulose-based wastes for adsorption of dyes from aqueous solutions.

    PubMed

    Annadurai, Gurusamy; Juang, Ruey-Shin; Lee, Duu-Jong

    2002-06-10

    Low-cost banana and orange peels were prepared as adsorbents for the adsorption of dyes from aqueous solutions. Dye concentration and pH were varied. The adsorption capacities for both peels decreased in the order methyl orange (MO) > methylene blue (MB) > Rhodamine B (RB) > Congo red (CR) > methyl violet (MV) > amido black 10B (AB). The isotherm data could be well described by the Freundlich and Langmuir equations in the concentration range of 10-120 mg/l. An alkaline pH was favorable for the adsorption of dyes. Based on the adsorption capacity, it was shown that banana peel was more effective than orange peel. Kinetic parameters of adsorption such as the Langergren rate constant and the intraparticle diffusion rate constant were determined. For the present adsorption process intraparticle diffusion of dyes within the particle was identified to be rate limiting. Both peel wastes were shown to be promising materials for adsorption removal of dyes from aqueous solutions.

  14. Patients' self-esteem before and after chemical peeling procedure.

    PubMed

    Kouris, Anargyros; Platsidaki, Eftychia; Christodoulou, Christos; Efstathiou, Vasiliki; Markantoni, Vasiliki; Armyra, Kalliopi; Potouridou, Irene; Rigopoulos, Dimitrios; Kontochristopoulos, Georgios

    2017-12-29

    Chemical peeling is a safe method, widely used to treat a variety of skin conditions and reduce the aging effects. This study aims to evaluate self-esteem among adolescents who undergo chemical peelings. One hundred and twenty six patients constituted the study group. Sixty seven individuals had undergone chemical peeling for therapeutic reasons and 59 individuals for cosmetic reasons. To assess patients' self-esteem, the Rosenberg's Self-esteem Scale (RSES) was used before and after treatment. The control group included 71 healthy, age- and sex-matched volunteers from the general population. They were also asked to complete the RSES, after the same time interval as the patients. The healthy controls (23.01 ± 3.12) presented statistically significantly higher self-esteem than both the groups of individuals who would be submitted to chemical peeling. Furthermore, patients who would undergo peeling for therapeutic reasons (21.58 ± 3.20) had statistically significantly higher self-esteem than those who would undergo the procedure for cosmetic reasons (18.97 ± 3.36). After the chemical peeling sessions, the self-esteem of patients treated for therapeutic reasons (23.48 ± 2.43) and of patients treated for cosmetic reasons (22.83 ± 3.34) improved statistically significantly, while the self-esteem of the healthy controls remained stable, as expected. Patients who undergo chemical peelings tend to have low levels of self-esteem. Although facial lesions in skin diseases such as acne, acne scars, rosacea, and melasma seem to have negative effect on individuals' self-consciousness, patients who would be submitted to chemical peeling in order to treat wrinkles, loss of radiance, and skin tone clarity have even lower self-esteem. Chemical peelings were shown to favorably affect patient's self-esteem since all patients showed an increase in self-esteem after treatment, while the control group experienced no change.

  15. Complications of Medium Depth and Deep Chemical Peels

    PubMed Central

    Nikalji, Nanma; Godse, Kiran; Sakhiya, Jagdish; Patil, Sharmila; Nadkarni, Nitin

    2012-01-01

    Superficial and medium depth peels are dynamic tools when used as part of office procedures for treatment of acne, pigmentation disorders, and photo-aging. Results and complications are generally related to the depth of wounding, with deeper peels providing more marked results and higher incidence of complications. Complications are also more likely with darker skin types, certain peeling agents, and sun exposure. They can range from minor irritations, uneven pigmentation to permanent scarring. In very rare cases, complications can be life-threatening. PMID:23378707

  16. Fragile Sites of 'Valencia' Sweet Orange (Citrus sinensis) Chromosomes Are Related with Active 45s rDNA.

    PubMed

    Lan, Hong; Chen, Chun-Li; Miao, Yin; Yu, Chang-Xiu; Guo, Wen-Wu; Xu, Qiang; Deng, Xiu-Xin

    2016-01-01

    Citrus sinensis chromosomes present a morphological differentiation of bands after staining by the fluorochromes CMA and DAPI, but there is still little information on its chromosomal characteristics. In this study, the chromosomes in 'Valencia' C. sinensis were analyzed by fluorescence in situ hybridization (FISH) using telomere DNA and the 45S rDNA gene as probes combining CMA/DAPI staining, which showed that there were two fragile sites in sweet orange chromosomes co-localizing at distended 45S rDNA regions, one proximally locating on B-type chromosome and the other subterminally locating on D-type chromosome. While the chromosomal CMA banding and 45S rDNA FISH mapping in the doubled haploid line of 'Valencia' C. sinensis indicated six 45S rDNA regions, four were identified as fragile sites as doubled comparing its parental line, which confirmed the cytological heterozygosity and chromosomal heteromorphisms in sweet orange. Furthermore, Ag-NOR identified two distended 45S rDNA regions to be active nucleolar organizing regions (NORs) in diploid 'Valencia' C. sinensis. The occurrence of quadrivalent in meiosis of pollen mother cells (PMCs) in 'Valencia' sweet orange further confirmed it was a chromosomal reciprocal translocation line. We speculated this chromosome translocation was probably related to fragile sites. Our data provide insights into the chromosomal characteristics of the fragile sites in 'Valencia' sweet orange and are expected to facilitate the further investigation of the possible functions of fragile sites.

  17. Microcontact Peeling as a New Method for Cell Micropatterning

    PubMed Central

    Yokoyama, Sho; Matsui, Tsubasa S.; Deguchi, Shinji

    2014-01-01

    Micropatterning is becoming a powerful tool for studying morphogenetic and differentiation processes of cells. Here we describe a new micropatterning technique, which we refer to as microcontact peeling. Polydimethylsiloxane (PDMS) substrates were treated with oxygen plasma, and the resulting hydrophilic layer of the surface was locally peeled off through direct contact with a peeling stamp made of aluminum, copper, or silicon. A hydrophobic layer of PDMS could be selectively exposed only at the places of the physical contact as revealed by water contact angle measurements and angle-resolved X-ray photoelectron spectroscopy, which thus enabled successful micropatterning of cells with micro-featured peeling stamps. This new micropatterning technique needs no procedure for directly adsorbing proteins to bare PDMS in contrast to conventional techniques using a microcontact printing stamp. Given the several unique characteristics, the present technique based on the peel-off of inorganic materials may become a useful option for performing cell micropatterning. PMID:25062030

  18. Cotyledon density measurements on valencia peanuts grown in the Southwest United States as a tool for developing food products

    USDA-ARS?s Scientific Manuscript database

    Valencia peanuts (Arachis hypogaea L. ssp. fastigiata) are able to complete seed development in an environment where extreme temperature variation and water deficit are common and growing season is short. Valencia seed can command a premium in food products as consumers like special properties like...

  19. Ammonia-nitrogen sorptional properties of banana peels.

    PubMed

    Chen, Yunnen; Ding, Lichao; Fan, Jingbiao

    2011-04-01

    Using modified banana peel as a biosorbent to treat water containing ammonia-nitrogen (NH4(+)-N) was studied. Related parameters in the sorptional process, such as chemical modification, pH, and contact time were investigated. The experimental results showed that banana peel modified by 30% sodium hydroxide (NaOH) and mesothermal microwaves (NMBPs) can greatly improve the sorption removal for NH4(+)-N. The kinetics study revealed that the sorption behavior better fit the pseudo-second-order equation than the Lagergren first-order equation. Fourier transform infrared absorption spectrum analysis of banana peels and NMBPs before and after NH4(+)-N sorption revealed that the activity of hydroxyl groups at the surface of the banana peels was strengthened after modification, and nitrogenous groups appeared after biosorpting the NH4(+)-N. In the end, metallurgical wastewater containing a low concentration of NH4(+)-N was treated by NMBPs. The initial NH4(+)-N concentration of 138 mg/L was reduced to 13 mg/L in 25 minutes by 4 g/L NMBPs at pH 10.

  20. Ripening influences banana and plantain peels composition and energy content.

    PubMed

    Emaga, Thomas Happi; Bindelle, Jérôme; Agneesens, Richard; Buldgen, André; Wathelet, Bernard; Paquot, Michel

    2011-01-01

    Musa sp. peels are widely used by smallholders as complementary feeds for cattle in the tropics. A study of the influence of the variety and the maturation stage of the fruit on fermentability and metabolisable energy (ME) content of the peels was performed using banana (Yangambi Km5) and plantain (Big Ebanga) peels at three stages of maturation in an in vitro model of the rumen. Peel samples were analysed for starch, free sugars and fibre composition. Samples were incubated in the presence of rumen fluid. Kinetics of gas production were modelled, ME content was calculated using prediction equation and short-chain fatty acids production and molar ratio were measured after 72 h of fermentation. Final gas production was higher in plantain (269-339 ml g(-1)) compared to banana (237-328 ml g(-1)) and plantain exhibited higher ME contents (8.9-9.7 MJ/kg of dry matter, DM) compared to banana (7.7-8.8 MJ/kg of DM). Butyrate molar ratio decreased with maturity of the peels. The main influence of the variety and the stage of maturation on all fermentation parameters as well as ME contents of the peels was correlated to changes in the carbohydrate fraction of the peels, including starch and fibre.

  1. ILM peeling in nontractional diabetic macular edema: review and metanalysis.

    PubMed

    Rinaldi, M; dell'Omo, R; Morescalchi, F; Semeraro, F; Gambicorti, E; Cacciatore, F; Chiosi, F; Costagliola, C

    2017-10-31

    To evaluate the effect of internal limiting membrane (ILM) peeling during vitrectomy for nontractional diabetic macular edema. PUBMED, MEDLINE and CENTRAL were reviewed using the following terms (or combination of terms): diabetic macular edema, nontractional diabetic macular edema, internal limiting membrane peeling, vitrectomy, Müller cells. Randomized and nonrandomized studies were included. The eligible studies compared anatomical and functional outcomes of vitrectomy with or without ILM peeling for tractional and nontractional diabetic macular edema. Postoperative best-corrected visual acuity and central macular thickness were considered, respectively, the primary and secondary outcomes. Meta-analysis on mean differences between vitrectomy with and without ILM peeling was performed using inverse variance method in random effects. Four studies with 672 patients were eligible for analysis. No significant difference was found between postoperative best-corrected visual acuity or best-corrected visual acuity change of ILM peeling group compared with nonpeeling group. There was no significant difference in postoperative central macular thickness and central macular thickness reduction between the two groups. The visual acuity outcomes in patients affected by nontractional diabetic macular edema using pars plana vitrectomy with ILM peeling versus no ILM peeling were not significantly different. A larger prospective and randomized study would be necessary.

  2. Facile and scalable synthesis of magnetite/carbon adsorbents by recycling discarded fruit peels and their potential usage in water treatment.

    PubMed

    Ma, Ji; Sun, Shuangshuang; Chen, Kezheng

    2017-06-01

    In this study, apple, banana and orange peels were used as precursor compounds for the mass production of magnetite/carbon adsorbents. A so-called "soak-calcination" procedure was employed by firstly soaking these waste fruit peels in FeCl 3 aqueous solutions and secondly calcining these precursors in the nitrogen atmosphere to yield final magnetite/carbon composites. This approach is quite simple and effective to synthesize carbon-based adsorbents on an industrial scale. The as-produced adsorbents feature the merits of appropriate ferromagnetism (>4emug -1 ), high adsorption capacity (several hundreds of milligrams per gram for adsorption of methyl blue, Congo red, rhodamine B and Cr 6+ ions), and good regenerability (>85%). Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Decreased retinal sensitivity after internal limiting membrane peeling for macular hole surgery.

    PubMed

    Tadayoni, Ramin; Svorenova, Ivana; Erginay, Ali; Gaudric, Alain; Massin, Pascale

    2012-12-01

    To compare the retinal sensitivity and frequency of microscotomas found by spectral domain optical coherence tomography (SD-OCT) combined with scanning laser ophthalmoscopy (SLO) microperimetry after idiopathic macular hole closure, in eyes that underwent internal limiting membrane (ILM) peeling and eyes that did not. This was a retrospective, non-randomised, comparative study. Combined SD-OCT and SLO microperimetry was performed in 16 consecutive eyes after closure of an idiopathic macular hole. A customised microperimetry pattern with 29 measurement points was used. The ILM was peeled in 8/16 eyes. The main outcome measure was mean retinal sensitivity. Mean retinal sensitivity (in dB) was lower after peeling: 9.80 ± 2.35 dB with peeling versus 13.19 ± 2.92 without (p=0.0209). Postoperative microscotomas were significantly more frequent after ILM peeling: 11.3 ± 6.6 points with retinal sensitivity below 10 dB in eyes that underwent peeling versus 2.9 ± 4.6 in those that did not (p=0.0093). These results suggest that ILM peeling may reduce retinal sensitivity, and significantly increase the incidence of microscotomas. Until a prospective trial confirming or not these results, it seems justified to avoid peeling the ILM when its potential benefit seems minor or unproved, and when peeling is carried out, to limit the surface peeled to the bare minimum.

  4. HEMI-TEMPORAL INTERNAL LIMITING MEMBRANE PEELING IS AS EFFECTIVE AND SAFE AS CONVENTIONAL FULL PEELING FOR MACULAR HOLE SURGERY.

    PubMed

    Shiono, Akira; Kogo, Jiro; Sasaki, Hiroki; Yomoda, Ryo; Jujo, Tatsuya; Tokuda, Naoto; Kitaoka, Yasushi; Takagi, Hitoshi

    2018-05-09

    To investigate the efficacy of hemi-temporal internal limiting membrane (ILM) peeling for idiopathic macular hole. The medical records of patients with macular holes who had undergone vitrectomy with ILM peeling were studied. Forty-two eyes with macular hole were divided into 2 groups based on surgical procedure (hemi-temporal ILM peeling [hemi group]: 15 eyes; 360° ILM peeling [360° group]: 27 eyes). The closure rates and distances between the optic disc and the intersection of two retinal vessels most closely located nasally or temporally to the macular hole were compared. The primary closure rates were not significantly different between the two groups (hemi group: 93.3%; 360° group: 92.5%, P = 0.92). The temporal retinal vessels in the hemi group were displaced 120.5 ± 102.0 µm toward the optic disc at 1 week postoperatively, which did not differ significantly from the 360° group (136.1 ± 106.1 µm) (P = 0.107). However, the nasal retinal vessels in the hemi group were displaced by 42.4 ± 42.9 µm at 1 week postoperatively, which was significantly less than the 90.1 ± 77.3 µm displacement seen in the 360° group (P = 0.040). Hemi-temporal ILM peeling may be preferable to 360° ILM peeling because of less displacement of the retina and greater safety.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

  5. Physico-chemical properties, rheology and degree of esterification of passion fruit (Passiflora edulis f. flavicarpa) peel flour.

    PubMed

    Coelho, Emanuela M; de Azevêdo, Luciana C; Viana, Arão C; Ramos, Ingrid G; Gomes, Raquel G; Lima, Marcos Dos S; Umsza-Guez, Marcelo A

    2018-01-01

    The peel of yellow passion fruit is as an agro-industrial waste of great environmental impact, representing more than 50% of the total weight of the fruit. For this reason, and also considering its importance as a source of functional components such as pectin, this organic waste is increasingly attracting the attention of researchers. The aim of this study was to investigate the physico-chemical composition and physical properties of this material, which may be of interest to the food industry. We obtained two samples of passion fruit peel flour applying different processes: flour without treatment (FWOT) and flour with treatment by maceration (FWT). It was found that the flour samples contain, respectively, 372.4 g kg -1 and 246.7 kg -1 of soluble fiber and, according to the FTIR analysis, this material corresponds to high and low methoxyl pectins, respectively. The flour obtained by maceration (FWT) offers greater benefits for industrial use, with 60% fewer tannins and greater thermal stability. In addition, this sample does not reabsorb moisture as easily, although FWOT also shows potential for use in dietary products. Considering the pseudoplastic properties of the flours, the application of both samples could be expanded to many industrial sectors. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  6. Identification of anti-cancer targets of eco-friendly waste Punica granatum peel by dual reverse virtual screening and binding analysis.

    PubMed

    Usha, Talambedu; Goyal, Arvind Kumar; Lubna, Syed; Prashanth, Hp; Mohan, T Madhan; Pande, Veena; Middha, Sushil Kumar

    2014-01-01

    Punica granatum (family: Lythraceae) is mainly found in Iran, which is considered to be its primary centre of origin. Studies on pomegranate peel have revealed antioxidant, anti-inflammatory, anti- angiogenesis activities, with prevention of premature aging and reducing inflammation. In addition to this it is also useful in treating various diseases like diabetes, maintaining blood pressure and treatment of neoplasms such as prostate and breast cancer. In this study we identified anti-cancer targets of active compounds like corilagin (tannins), quercetin (flavonoids) and pseudopelletierine (alkaloids) present in pomegranate peel by employing dual reverse screening and binding analysis. The potent targets of the pomegranate peel were annotated by the PharmMapper and ReverseScreen 3D, then compared with targets identified from different Bioassay databases (NPACT and HIT's). Docking was then further employed using AutoDock pyrx and validated through discovery studio for studying molecular interactions. A number of potent anti-cancerous targets were attained from the PharmMapper server according to their fit score and from ReverseScreen 3D server according to decreasing 3D scores. The identified targets now need to be further validated through in vitro and in vivo studies.

  7. Peeling skin syndrome associated with novel variant in FLG2 gene.

    PubMed

    Alfares, Ahmed; Al-Khenaizan, Sultan; Al Mutairi, Fuad

    2017-12-01

    Peeling skin syndrome is a rare genodermatosis characterized by variably pruritic superficial generalized peeling of the skin with several genes involved until now little is known about the association between FLG2 and peeling skin syndrome. We describe multiple family members from a consanguineous Saudi family with peeling skin syndrome. Next Generation Sequencing identifies a cosegregating novel variant in FLG2 c.632C>G (p.Ser211*) as a likely etiology in this family. Here, we reported on the clinical manifestation of homozygous loss of function variant in FLG2 as a disease-causing gene for peeling skin syndrome and expand the dermatology findings. © 2017 Wiley Periodicals, Inc.

  8. A comparison of dynamic mechanical properties of processing-tomato peel as affected by hot lye and infrared radiation heating for peeling

    USDA-ARS?s Scientific Manuscript database

    This study investigated the viscoelastic characteristics of tomato skins subjected to conventional hot lye peeling and emerging infrared-dry peeling by using dynamic mechanical analysis (DMA). Three DMA testing modes, including temperature ramp, frequency sweep, and creep behavior test, were conduct...

  9. Production and characterization of films based on blends of chitosan from blue crab (Callinectes sapidus) waste and pectin from Orange (Citrus sinensis Osbeck) peel.

    PubMed

    Baron, Ricardo Duran; Pérez, Latife Lúquez; Salcedo, Jesús Mejía; Córdoba, Luis Pérez; Sobral, Paulo José do Amaral

    2017-05-01

    The objective of this study was to develop and characterize films based on blends of chitosan and pectin, produced in laboratory scale, from industrial wastes. The chitosan was obtained by termoalcaline deacetylation of chitin, extracted from blue crab (Callinectes sapidus) waste and characterized according to degree of deacetylation (DD) and viscosimetric molecular weight (Mw); and pectin was extracted by conventional heating, from orange (Citrus sinensis Osbeck) peel and characterized according to degree of esterification (DE) and molecular weight (Mw). The Ch:P based films were prepared by the casting method in different Ch:P ratios [0: 100, 25:75, 50:50, 75:25 and 100:0], and compared to two controls [0:100 and 100:0], of commercial pectin and chitosan. Glycerol was used as a plasticizer at concentrations of 0.2g/g macromolecules. The addition of high concentrations of pectin in the formulations resulted in films with high solubility and an increase in moisture. No significant difference (P>0.05) in the degree of swelling (DS) and water vapor permeability (WVP) of the films was observed. Ch:P blend films were less stiff and therefore more elastic and flexible than films based on only one biopolymer. The control films presented better results in terms of color, being brighter and less opaque than other film formulations. These data suggest that chitosan or pectin obtained from agro-industrial waste is a potential matrix to produce biodegradable films for future food applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Performance of Natural Dye and Counter Electrode from Robusta Coffee Beans Peel Waste for Fabrication of Dye-Sensitized Solar Cell (DSSC)

    NASA Astrophysics Data System (ADS)

    Setiawan, T.; Subekti, W. Y.; Nur'Adya, S. S.; Ilmiah, K.; Ulfa, S. M.

    2018-01-01

    The DSSC prototype using activated carbon (AC) and natural dye from Robusta coffee bean peels have been investigated. The natural dye obtained from the extraction of Robusta coffee bean peels is identified as anthocyanin by UV-Vis spectrophotometer at maximum wavelength 219.5 nm and 720.0 nm in methanol. From the FT-IR analysis, the vibration of O-H observed at 3385 cm-1, C=O at 1618 cm-1, and C-O-C at 1065 cm-1. The counter electrode prepared by calcined the peels at 300°C. Surface analyser of AC showed the larger surface area compared prior activation. The DSSC prototype was prepared using FTO glass (2x2 cm) coated with carbon paste in various thickness. The working electrode is coated with the TiO2 paste. The optimum voltage measured was 395mV (300 μL of CA), 334 mV (200 μL AC), and 254 mV (100 μL AC). From this result, we understand that the thickness of counter electrode influent the voltage of the DSSC.

  11. Conversion of food processing wastes to biofuel using clostridia.

    PubMed

    Abd-Alla, Mohamed Hemida; Zohri, Abdel-Naser Ahmed; El-Enany, Abdel-Wahab Elsadek; Ali, Shimaa Mohamed

    2017-12-01

    This study aims to demonstrate the recycling of food processing wastes as a low cost-effective substrate for acetone - butanol - ethanol (ABE) production. Potato peels and cheese whey were utilized during fermentation with eight local Clostridium strains in addition to the commercial strain, C. acetobutylicum ATCC 824 for ABE and organic acids production. From potato peels, Clostridium beijerinckii ASU10 produced the highest ABE production (17.91 g/l) representing 61.3% butanol (10.98 g/l), 33.6% acetone (6.02 g/l) and 5.1% ethanol (0.91 g/l). While, C. chauvoei ASU12 showed the highest acid production (8.15 g/l) including 5.50 and 2.61 g/l acetic and butyric acids, respectively. Use of cheese whey as fermentable substrate exhibited a substantial increase in ethanol ratio and decrease in butanol ratio compared to those produced from potato peels. Clostridium beijerinckii ASU5 produced the highest ABE concentration (7.13 g/l) representing 50.91% butanol (3.63 g/l), 35.34% acetone (2.52 g/l) and 13.74% ethanol (0.98 g/l). The highest acid production (8.00 g/l) was obtained by C. beijerinckii ASU5 representing 4.89 and 3.11 g/l for acetic and butyric acid, respectively. Supplementation of potato peels with an organic nitrogen source showed NH 4 NO 3 promoted ABE production more than yeast extract. In conclusion, this study introduced an ecofriendly and economical practice for utilization of food processing wastes (renewable substrates as potato peels and cheese whey) for biofuel production using various Clostridium strains. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Biosynthesis of AgNPs using Carica Papaya peel extract and evaluation of its antioxidant and antimicrobial activities.

    PubMed

    Kokila, T; Ramesh, P S; Geetha, D

    2016-12-01

    Waste fruit peel mediated synthesis of silver nanoparticles (AgNPs) is a green chemistry approach that links nanotechnology and biotechnology. Using biological medium such as peel extract for the biosynthesis of nanoparticles is an ecofriendly and emerging scientific trend. With this back drop the present study focused on the biosynthesis of AgNPs using Carica Papaya peel extract (CPPE) and evaluation of its antimicrobial potentials of the nanoparticles against different human pathogens and to investigate the free radical scavenging activity. Water soluble antioxidant constituents present in Carica Papaya peel extract were mainly responsible for the reduction of silver ions to nanosized Ag particles. UV-vis spectral analysis shows surface plasmon resonance band at 430nm. The presence of active proteins and phenolic groups present in the biomass before and after reduction was identified by Fourier transform infrared spectroscopy. X-ray diffraction study shows the average size of the silver nanoparticles is in the range of 28nm, as well as revealed their face centered cubic structure. Atomic force microscope image gives the 3D topological characteristic of silver nanoparticles and the particle size ranges from 10 to 30nm. The average particle size distribution of silver nanoparticles is 161nm (Dynamic light scattering) and the corresponding average zeta potential value is -20.5mV, suggesting higher stability of silver nanoparticles. Biologically synthesized nanoparticles efficiently inhibited pathogenic organisms both gram-positive and gram-negative bacteria. The biosynthesized nanoparticles might serve as a potent antioxidant as revealed by DPPH and ABT S+ assay. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Influence of azelaic and mandelic acid peels on sebum secretion in ageing women.

    PubMed

    Wójcik, Aneta; Kubiak, Marlena; Rotsztejn, Helena

    2013-06-01

    Azelaic acid and mandelic acid are superficial peels commonly applied in people of various age groups. As they are mild and do not cause any side effects, they are also often used in elderly people. To compare the influence of azelaic and mandelic acid peels on facial sebum secretion in mature women aged 49-71 years. The level of secreted sebum was measured in 28 women. Eleven women were treated with azelaic acid peel and 17 with mandelic acid peel. Each of the peels was applied five times with 2-week intervals. The measurements were made on the cheeks and chin with the use of Sebumeter SM 15 (Courage & Khazaka, Germany). The last measurement, i.e. the sixth one, was made 2 weeks after the treatment. We observed a significant increase in sebum secretion in the U-zone after the application of 20% azelaic peel and 40% mandelic peel. Neither peel significantly affected sebum secretion in the T-zone. Peels with 20% azelaic acid and 40% mandelic acid might be considered treatments which contribute to an increase in sebum secretion in ageing women.

  14. Peeling without precursors

    NASA Astrophysics Data System (ADS)

    Lister, John; Skinner, Dominic; Large, Tim

    2017-11-01

    The peeling by fluid injection of an elastic sheet away from a substrate is often regularised by invoking a thin prewetting film or a low-viscosity phase in the tip. Here we analyse fluid-driven peeling without such precursors, and consider an elastic sheet either bonded to, or simply laid on, an elastic substrate. To resolve the `elastic contact-line problem' that arises from viscous flow and beam theory, we determine the near-tip behaviour from lubrication theory coupled to the full equations of elasticity and fracture. The result is a law for the tip propagation speed in terms of the remote loading and the toughness of the sheet-substrate bonding (which might be zero). There are distinct modes of failure, according to whether there is slip ahead of the fluid front. The propagation-speed law gives rise to new similarity solutions for the spread of a fluid-filled blister in different regimes.

  15. Acral peeling skin syndrome: a case of two brothers.

    PubMed

    Wakade, Oojwala; Adams, Beth; Shwayder, Tor

    2009-01-01

    We report two brothers of Middle Eastern descent with consanguineous parents who present with numerous fragile, flaccid blisters on the hands and feet. In addition to spontaneous peeling, they can manually peel skin from acral areas without pain. The symptoms worsen with warm temperatures, excessive water exposure, and perspiration. Two biopsies from flaccid blisters on the feet were taken from the older brother, which revealed cleavage at the level of the stratum corneum. A diagnosis of acral peeling skin syndrome was made.

  16. Production of copolymer, poly (hydroxybutyrate-co-hydroxyvalerate) by Halomonas campisalis MCM B-1027 using agro-wastes.

    PubMed

    Kulkarni, S O; Kanekar, P P; Jog, J P; Sarnaik, S S; Nilegaonkar, S S

    2015-01-01

    For cost effective production of PHA, agro-wastes like fruit peels, bagasse and deoiled cakes were screened as a sole source of carbon. Halomonas campisalis MCM B-1027, which was isolated from one of the extreme environment, i.e. Lonar Lake, India, was explored for the production of PHA using fruit peels and bagasse having fermentable sugars. Among the agro-wastes tested, 1% (v/v) aqueous extract of bagasse was found to be the optimum carbon source with 47% PHA production on dry cell weight basis. Significant amount of total sugars are utilized and converted into cell mass and PHA, e.g. 62% sugar utilized from bagasse extract, 84% from orange peel extract and 71% from banana peel extract as compared to 51% in case of maltose. Hence the cost of production would be positively reduced. The detailed characterization of PHA formed by H. campisalis using bagasse extract as sole carbon source revealed that the organism produces a copolymer of PHB-co-PHV (94.4:5.6) having molecular weight M(w) 1.394 × 10(6) and melting temperature 168.9 °C. Production of PHA by H. campisalis using aqueous extract of fruit peels and a copolymer PHB-co-PHV using aqueous extract of bagasse is presumably the first report. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Technical Note: Dosimetry of Leipzig and Valencia applicators without the plastic cap

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Granero, D., E-mail: dgranero@eresa.com; Candela-Juan, C.; Vijande, J.

    2016-05-15

    Purpose: High dose rate (HDR) brachytherapy for treatment of small skin lesions using the Leipzig and Valencia applicators is a widely used technique. These applicators are equipped with an attachable plastic cap to be placed during fraction delivery to ensure electronic equilibrium and to prevent secondary electrons from reaching the skin surface. The purpose of this study is to report on the dosimetric impact of the cap being absent during HDR fraction delivery, which has not been explored previously in the literature. Methods: GEANT4 Monte Carlo simulations (version 10.0) have been performed for the Leipzig and Valencia applicators with andmore » without the plastic cap. In order to validate the Monte Carlo simulations, experimental measurements using radiochromic films have been done. Results: Dose absorbed within 1 mm of the skin surface increases by a factor of 1500% for the Leipzig applicators and of 180% for the Valencia applicators. Deeper than 1 mm, the overdosage flattens up to a 10% increase. Conclusions: Differences of treating with or without the plastic cap are significant. Users must check always that the plastic cap is in place before any treatment in order to avoid overdosage of the skin. Prior to skin HDR fraction delivery, the timeout checklist should include verification of the cap placement.« less

  18. Sustainable biobutanol production from pineapple waste by using Clostridium acetobutylicum B 527: Drying kinetics study.

    PubMed

    Khedkar, Manisha A; Nimbalkar, Pranhita R; Gaikwad, Shashank G; Chavan, Prakash V; Bankar, Sandip B

    2017-02-01

    Present investigation explores the use of pineapple peel, a food industry waste, for acetone-butanol-ethanol (ABE) production using Clostridium acetobutylicum B 527. Proximate analysis of pineapple peel shows that it contains 35% cellulose, 19% hemicellulose, and 16% lignin on dry basis. Drying experiments on pineapple peel waste were carried out in the temperature range of 60-120°C and experimental drying data was modeled using moisture diffusion control model to study its effect on ABE production. The production of ABE was further accomplished via acid hydrolysis, detoxification, and fermentation process. Maximum total sugar release obtained by using acid hydrolysis was 97g/L with 95-97% and 10-50% removal of phenolics and acetic acid, respectively during detoxification process. The maximum ABE titer obtained was 5.23g/L with 55.6% substrate consumption when samples dried at 120°C were used as a substrate (after detoxification). Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Demonstration tests of infrared peeling system with electrical emitters for tomatoes

    USDA-ARS?s Scientific Manuscript database

    Infrared (IR) dry-peeling is an emerging technology that could avoid the drawbacks of steam and lye peeling of tomatoes. The objectives of this research was to evaluate the performance of an IR peeling system at two tomato processing plants located in California and to compare product quality, peela...

  20. Operational forecasting of daily temperatures in the Valencia Region. Part II: minimum temperatures in winter.

    NASA Astrophysics Data System (ADS)

    Gómez, I.; Estrela, M.

    2009-09-01

    Extreme temperature events have a great impact on human society. Knowledge of minimum temperatures during winter is very useful for both the general public and organisations whose workers have to operate in the open, e.g. railways, roadways, tourism, etc. Moreover, winter minimum temperatures are considered a parameter of interest and concern since persistent cold-waves can affect areas as diverse as public health, energy consumption, etc. Thus, an accurate forecasting of these temperatures could help to predict cold-wave conditions and permit the implementation of strategies aimed at minimizing the negative effects that low temperatures have on human health. The aim of this work is to evaluate the skill of the RAMS model in determining daily minimum temperatures during winter over the Valencia Region. For this, we have used the real-time configuration of this model currently running at the CEAM Foundation. To carry out the model verification process, we have analysed not only the global behaviour of the model for the whole Valencia Region, but also its behaviour for the individual stations distributed within this area. The study has been performed for the winter forecast period from 1 December 2007 - 31 March 2008. The results obtained are encouraging and indicate a good agreement between the observed and simulated minimum temperatures. Moreover, the model captures quite well the temperatures in the extreme cold episodes. Acknowledgement. This work was supported by "GRACCIE" (CSD2007-00067, Programa Consolider-Ingenio 2010), by the Spanish Ministerio de Educación y Ciencia, contract number CGL2005-03386/CLI, and by the Regional Government of Valencia Conselleria de Sanitat, contract "Simulación de las olas de calor e invasiones de frío y su regionalización en la Comunidad Valenciana" ("Heat wave and cold invasion simulation and their regionalization at Valencia Region"). The CEAM Foundation is supported by the Generalitat Valenciana and BANCAIXA (Valencia

  1. Operational forecasting of daily temperatures in the Valencia Region. Part I: maximum temperatures in summer.

    NASA Astrophysics Data System (ADS)

    Gómez, I.; Estrela, M.

    2009-09-01

    Extreme temperature events have a great impact on human society. Knowledge of summer maximum temperatures is very useful for both the general public and organisations whose workers have to operate in the open, e.g. railways, roadways, tourism, etc. Moreover, summer maximum daily temperatures are considered a parameter of interest and concern since persistent heat-waves can affect areas as diverse as public health, energy consumption, etc. Thus, an accurate forecasting of these temperatures could help to predict heat-wave conditions and permit the implementation of strategies aimed at minimizing the negative effects that high temperatures have on human health. The aim of this work is to evaluate the skill of the RAMS model in determining daily maximum temperatures during summer over the Valencia Region. For this, we have used the real-time configuration of this model currently running at the CEAM Foundation. To carry out the model verification process, we have analysed not only the global behaviour of the model for the whole Valencia Region, but also its behaviour for the individual stations distributed within this area. The study has been performed for the summer forecast period of 1 June - 30 September, 2007. The results obtained are encouraging and indicate a good agreement between the observed and simulated maximum temperatures. Moreover, the model captures quite well the temperatures in the extreme heat episodes. Acknowledgement. This work was supported by "GRACCIE" (CSD2007-00067, Programa Consolider-Ingenio 2010), by the Spanish Ministerio de Educación y Ciencia, contract number CGL2005-03386/CLI, and by the Regional Government of Valencia Conselleria de Sanitat, contract "Simulación de las olas de calor e invasiones de frío y su regionalización en la Comunidad Valenciana" ("Heat wave and cold invasion simulation and their regionalization at Valencia Region"). The CEAM Foundation is supported by the Generalitat Valenciana and BANCAIXA (Valencia, Spain).

  2. Influence of azelaic and mandelic acid peels on sebum secretion in ageing women

    PubMed Central

    Wójcik, Aneta; Kubiak, Marlena

    2013-01-01

    Introduction Azelaic acid and mandelic acid are superficial peels commonly applied in people of various age groups. As they are mild and do not cause any side effects, they are also often used in elderly people. Aim To compare the influence of azelaic and mandelic acid peels on facial sebum secretion in mature women aged 49-71 years. Material and methods The level of secreted sebum was measured in 28 women. Eleven women were treated with azelaic acid peel and 17 with mandelic acid peel. Each of the peels was applied five times with 2-week intervals. The measurements were made on the cheeks and chin with the use of Sebumeter SM 15 (Courage & Khazaka, Germany). The last measurement, i.e. the sixth one, was made 2 weeks after the treatment. Results We observed a significant increase in sebum secretion in the U-zone after the application of 20% azelaic peel and 40% mandelic peel. Neither peel significantly affected sebum secretion in the T-zone. Conclusions Peels with 20% azelaic acid and 40% mandelic acid might be considered treatments which contribute to an increase in sebum secretion in ageing women. PMID:24278065

  3. Chemistry with a Peel.

    ERIC Educational Resources Information Center

    Borer, Londa; Larsen, Eric

    1997-01-01

    Presents experiments that introduce natural product chemistry into high school classrooms. In the laboratory activities, students isolate and analyze the oil in orange peels. Students also perform a steam distillation and learn about terpenes. (DDR)

  4. [Optical coherence tomography and microperimetry after internal limiting membrane peeling for epiretinal membrane].

    PubMed

    Grimbert, P; Lebreton, O; Weber, M

    2014-06-01

    To evaluate the anatomical and functional consequences of internal limiting membrane (ILM) peeling in epiretinal membrane (ERM) surgery. Retrospective single-center study including consecutive patients operated on for idiopathic ERM. The integrity of the ILM was assessed by ILM Blue® staining after removal of the ERM: either the peeling was spontaneous (group 1) or a complementary peeling was required (group 2). Pre- and post-operatively (1 and 6 months), all patients were analyzed using visual acuity, SD-OCT (Spectralis HRA OCT, Heidelberg, Germany) and microperimetry (OPKO/OTI, Miami, USA). Twenty-one eyes of 21 patients were included: 12 "active ILM peelings" and 9 "spontaneous peelings". In both groups, visual acuity increased significantly after surgery. Microperimetry revealed more microscotomata at 1 and 6 months for active peeling (P<0.05). Their location corresponded more often to the site where the ERM or ILM was grasped, based on surgical videos (P<0.05), and with the appearance of inner retinal defects using en face OCT. ILM peeling is frequently performed to reduce ERM recurrence. Despite lack of effect on visual acuity, active ILM peeling increases the incidence of microscotomas related to the site where the ERM or ILM is grasped. Active ILM peeling may be responsible for postoperative visual discomfort related to microscopic trauma during peeling. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  5. The Valencia trough and the origin of the western Mediterranean basins

    NASA Astrophysics Data System (ADS)

    Vegas, R.

    1992-03-01

    Evolutionary models for the Valencia trough must be necessarily related to the Neogene-Present geodynamics of the western Mediterranean basins. All these basins occupy new space created in the wake of the westward translation of the Alboran block and the counter-clockwise rotation of the Corso-Sardinian block. This escape-tectonics, microplate dispersal, model can account for the co-existence and progressive migration of compressional and extensional strain fields within the Africa-Europe broad zone of convergence. In this escape-tectonics model, the Valencia trough has resulted in a complex evolution which includes: (1) latest Oligocene-Early Miocene rifting along the Catalan-Valencian margin due to the opening of the Gulf of Lions; (2) almost simultaneous, Early Miocene, transpressive thrusting in the Balearic margin related to the initiation of displacement of the Alboran block; and (3) Late Miocene generalized extension as a consequence of the opening of the South Balearic basin.

  6. Cross-Validation of Survival Bump Hunting by Recursive Peeling Methods

    PubMed Central

    Dazard, Jean-Eudes; Choe, Michael; LeBlanc, Michael; Rao, J. Sunil

    2015-01-01

    We introduce a survival/risk bump hunting framework to build a bump hunting model with a possibly censored time-to-event type of response and to validate model estimates. First, we describe the use of adequate survival peeling criteria to build a survival/risk bump hunting model based on recursive peeling methods. Our method called “Patient Recursive Survival Peeling” is a rule-induction method that makes use of specific peeling criteria such as hazard ratio or log-rank statistics. Second, to validate our model estimates and improve survival prediction accuracy, we describe a resampling-based validation technique specifically designed for the joint task of decision rule making by recursive peeling (i.e. decision-box) and survival estimation. This alternative technique, called “combined” cross-validation is done by combining test samples over the cross-validation loops, a design allowing for bump hunting by recursive peeling in a survival setting. We provide empirical results showing the importance of cross-validation and replication. PMID:26997922

  7. Destabilization of low-n peeling modes by trapped energetic particles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hao, G. Z.; Wang, A. K.; Mou, Z. Z.

    2013-06-15

    The kinetic effect of trapped energetic particles (EPs), arising from perpendicular neutral beam injection, on the stable low-n peeling modes in tokamak plasmas is investigated, through numerical solution of the mode's dispersion relation derived from an energy principle. A resistive-wall peeling mode with m/n=6/1, with m and n being the poloidal and toroidal mode numbers, respectively, is destabilized by trapped EPs as the EPs' pressure exceeds a critical value β{sub c}{sup *}, which is sensitive to the pitch angle of trapped EPs. The dependence of β{sub c}{sup *} on the particle pitch angle is eventually determined by the bounce averagemore » of the mode eigenfunction. Peeling modes with higher m and n numbers can also be destabilized by trapped EPs. Depending on the wall distance, either a resistive-wall peeling mode or an ideal-kink peeling mode can be destabilized by EPs.« less

  8. Multiple extrafoveal macular holes following internal limiting membrane peeling.

    PubMed

    Hussain, Nazimul; Mitra, Sandip

    2018-01-01

    Internal limiting membrane (ILM) peeling has been the standard of treatment for macular holes. Besides, causing retinal nerve fiber layer surface abnormality, postoperative extrafoveal multiple retinal holes is a rare phenomenon following ILM peeling. We report an unusual complication of eight extrafoveal macular holes occurring following ILM peeling. A 60-year-old male presented with complaints of decreased and distorted vision in the right eye. He was diagnosed as having epiretinal membrane with lamellar macular hole. He underwent 23G pars plana vitrectomy, brilliant blue assisted ILM peeling and fluid gas exchange. Intraoperatively, ILM was found to be adherent to the underlying neurosensory retina. One month after cataract surgery, he underwent YAG capsulotomy in the right eye. He complained of visual distortion. His fundus evaluation in the right eye showed multiple (eight) extrafoveal retinal holes temporal to the macula clustered together. This case demonstrated that peeling of ILM, especially when it is adherent to the underlying neurosensory retina, may cause unwanted mechanical trauma to the inner retina. Glial apoptosis and neuronal degeneration may presumably play a role in delayed appearance of multiple (eight) extrafoveal macular holes, which has not been reported earlier.

  9. Multiple extrafoveal macular holes following internal limiting membrane peeling

    PubMed Central

    Hussain, Nazimul; Mitra, Sandip

    2018-01-01

    Objective Internal limiting membrane (ILM) peeling has been the standard of treatment for macular holes. Besides, causing retinal nerve fiber layer surface abnormality, postoperative extrafoveal multiple retinal holes is a rare phenomenon following ILM peeling. We report an unusual complication of eight extrafoveal macular holes occurring following ILM peeling. Case presentation A 60-year-old male presented with complaints of decreased and distorted vision in the right eye. He was diagnosed as having epiretinal membrane with lamellar macular hole. He underwent 23G pars plana vitrectomy, brilliant blue assisted ILM peeling and fluid gas exchange. Intraoperatively, ILM was found to be adherent to the underlying neurosensory retina. One month after cataract surgery, he underwent YAG capsulotomy in the right eye. He complained of visual distortion. His fundus evaluation in the right eye showed multiple (eight) extrafoveal retinal holes temporal to the macula clustered together. Conclusion This case demonstrated that peeling of ILM, especially when it is adherent to the underlying neurosensory retina, may cause unwanted mechanical trauma to the inner retina. Glial apoptosis and neuronal degeneration may presumably play a role in delayed appearance of multiple (eight) extrafoveal macular holes, which has not been reported earlier. PMID:29760571

  10. INCOMPLETE REPAIR OF RETINAL STRUCTURE AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING.

    PubMed

    Hisatomi, Toshio; Tachibana, Takashi; Notomi, Shoji; Nakatake, Shunji; Fujiwara, Kohta; Murakami, Yusuke; Ikeda, Yasuhiro; Yoshida, Shigeo; Enaida, Hiroshi; Murata, Toshinori; Sakamoto, Taiji; Sonoda, Koh-Hei; Ishibashi, Tatsuro

    2017-08-01

    To examine retinal changes after vitrectomy with internal limiting membrane (ILM) peeling, we used a cynomolgus monkey model and focused on surgical damages of ILM peeling for long observational period of 3 years. Vitrectomy was performed followed by ILM peeling similar to clinical settings in humans. Ultrastructural changes of the retina were investigated by light, transmission, and scanning electron microscopy at 3 months and 3 years after ILM peeling. Ultrastructural study showed that the ILM peeled area was still clearly recognized after 3 years. The Müller cell processes covered most of the retina; however, the nerve fiber layer was partly uncovered and exposed to the vitreous space. The arcuate linear nerve fiber bundles were observed as comparable with dissociated optic nerve fiber layer appearance. Small round retinal surface defects were also observed around macula, resembling the dimple sign. Forceps-related retinal thinning was also found on the edge of ILM peeling, where we started peeling with fine forceps. The ultrastructural studies showed that most of ILM peeling area was covered with glial cells during wound healing processes. Retinal changes were found comparable with dissociated optic nerve fiber layer appearance or dimple sign, which were clinically observed with optical coherence tomography.

  11. Facial peeling skin syndrome: a case report and a brief review.

    PubMed

    Janjua, Shahbaz Ahmad; Hussain, Ijaz; Khachemoune, Amor

    2007-03-01

    Peeling skin syndrome is an extremely rare genodermatosis of possible autosomal recessive inheritance, characterized by asymptomatic spontaneous exfoliation of the stratum corneum at a subcorneal or intracorneal level. It usually presents at birth or appears later in early childhood. The condition may be generalized or localized. Here we describe a case of localized continual skin peeling limited to the facial skin in a 6-month-old infant, with two other members of the family affected with the same condition. A few cases of localized skin peeling limited to the acral surfaces have been described in the literature, but a familial case of localized skin peeling limited to the facial skin has not been described before. We believe that our patient represents a new subtype of peeling skin syndrome, limited to the skin of the face.

  12. Intermittent stick-slip dynamics during the peeling of an adhesive tape from a roller.

    PubMed

    Cortet, Pierre-Philippe; Dalbe, Marie-Julie; Guerra, Claudia; Cohen, Caroline; Ciccotti, Matteo; Santucci, Stéphane; Vanel, Loïc

    2013-02-01

    We study experimentally the fracture dynamics during the peeling at a constant velocity of a roller adhesive tape mounted on a freely rotating pulley. Thanks to a high speed camera, we measure, in an intermediate range of peeling velocities, high frequency oscillations between phases of slow and rapid propagation of the peeling fracture. This so-called stick-slip regime is well known as the consequence of a decreasing fracture energy of the adhesive in a certain range of peeling velocity coupled to the elasticity of the peeled tape. Simultaneously with stick slip, we observe low frequency oscillations of the adhesive roller angular velocity which are the consequence of a pendular instability of the roller submitted to the peeling force. The stick-slip dynamics is shown to become intermittent due to these slow pendular oscillations which produce a quasistatic oscillation of the peeling angle while keeping constant the peeling fracture velocity (averaged over each stick-slip cycle). The observed correlation between the mean peeling angle and the stick-slip amplitude questions the validity of the usually admitted independence with the peeling angle of the fracture energy of adhesives.

  13. Lactic acid peeling in superficial acne scarring in Indian skin.

    PubMed

    Sachdeva, Silonie

    2010-09-01

    Chemical peeling with both alpha and beta hydroxy acids has been used to improve acne scarring with pigmentation. Lactic acid, a mild alpha hydroxy acid, has been used in the treatment of various dermatological indications but no study is reported in acne scarring with pigmentation. To evaluate the efficacy and safety of full strength pure lactic acid 92% (pH 2.0) chemical peel in superficial acne scarring in Indian skin. Seven patients, Fitzpatrick skin type IV-V, in age group 20-30 years with superficial acne scarring were enrolled in the study. Chemical peeling was done with lactic acid at an interval of 2 weeks to a maximum of four peels. Pre- and post-peel clinical photographs were taken at every session. Patients were followed every month for 3 months after the last peel to evaluate the effects. At the end of 3 months, there was definite improvement in the texture, pigmentation, and appearance of the treated skin, with lightening of scars. Significant improvement (greater than 75% clearance of lesions) occurred in one patient (14.28%), good improvement (51-75% clearance) in three patients (42.84%), moderate improvement (26-50% clearance) in two patients (28.57%), and mild improvement (1-25% clearance) in one patient (14.28%). © 2010 Wiley Periodicals, Inc.

  14. Inhibitors of 15-lipoxygenase from orange peel.

    PubMed

    Malterud, K E; Rydland, K M

    2000-11-01

    A series of polymethoxylated flavonoids has been isolated from orange peel, and their inhibitory activity toward soybean 15-lipoxygenase was determined. The strongest inhibition was shown by 3,5,6,7,3',4'-hexamethoxyflavone (IC(50) = 49 +/- 5 microM). Sinensetin, nobiletin, tangeretin, tetramethylscutellarein, and 3,5, 6,7,8,3',4'-heptamethoxyflavone were somewhat less active, with IC(50) values of 70-86 microM, comparable to the positive control quercetin (IC(50) = 68 +/- 5 microM). Demethylation apparently results in less active compounds, with 5-O-demethylsinensetin having an IC(50) value of 144 +/- 10 microM. Some other orange peel constituents were isolated and tested as well, hesperidin (IC(50) = 180 +/- 10 microM) and ferulic acid (111 +/- 2 microM), showing moderate activity. The polymethoxylated flavonoids were virtually inactive as scavengers of the diphenylpicrylhydrazyl radical. Hesperidin was only slightly active (24.2 +/- 0.7% scavenged at a concentration of 2 mM), and ferulic acid showed good activity (IC(50) = 86.4 +/- 0.7 microM). From this, it appears that orange peel constituents may counteract enzymatic lipid peroxidation processes catalyzed by 15-lipoxygenase in vitro. The radical scavenging activity of orange peel extracts is only modest.

  15. Trace element concentrations in the fruit peels and trunks of Musa paradisiaca.

    PubMed

    Selema, M D; Farago, M E

    1996-08-01

    Chemical analyses for the elementary compositions of the ashes of the fruit peels and trunks of the tropical plantain Musa paradisiaca have been undertaken. The elements, categorized as trace elements, generally are found to have higher mean concentrations in the fruit peels than in the trunks (except in the case of Zn). Their peel-trunk uptake ratios have been calculated and range between 1 and 4, showing normal levels of accumulations in the fruit peels over the trunks.

  16. Nutrient, phytochemical, and antinutrient composition of Citrus maxima fruit juice and peel extract.

    PubMed

    Ani, Peace Nwanneka; Abel, Happiness Chiamaka

    2018-05-01

    Nutrient, phytochemical, and antinutrient composition of Citrus maxima fruit juice and peel extract were determined. The fruit was procured from a garden in Trans-Ekulu, Enugu East Local Government Area, Enugu State, Nigeria. Mature undamaged Citrus maxima fruits were thoroughly washed with distilled water to remove contamination, dirt, and air-dried. The peel was separated from the pulp. The pulp (100 g) was blended and filtered through a muslin cloth to obtain a clear juice. The peel (50 g) was macerated with 200 ml of ethanol for 20 min. The peel extract was filtered through filter paper. The supernatant was concentrated by rotary evaporation. The peel extract was weighed and stored in a plastic container until needed. Proximate, mineral, vitamins, antinutrient, and phytochemical composition of the juice and peel extract were determined using standard procedures. Citrus maxima peel extract contains significantly ( p  < .05) higher crude fiber (2.58%), fat (9.74%), ash (2.49%), and carbohydrate (71.57%) compared with Citrus maxima juice. Alkaloid, phenolics, and flavonoids were also significantly ( p  < .05) higher in the peel extract. The mineral composition revealed the order Ca > Na > Ph > Fe > Mg > K in the juice and Ca > Ph > Na > Fe > K > Mg in the peel extract. Vitamin C content of the juice and peel extract were 26.36 mg/100 g and 19.34 mg/100 g, respectively. Citrus maxima peel is highly nutritive and rich in phytochemicals, further research is recommended to investigate its therapeutic effect.

  17. The essential oil from Citrus limetta Risso peels alleviates skin inflammation: In-vitro and in-vivo study.

    PubMed

    Maurya, Anil Kumar; Mohanty, Shilpa; Pal, Anirban; Chanotiya, Chandan Singh; Bawankule, Dnyaneshawar Umrao

    2018-02-15

    Citrus fruit peels are traditionally used in folk medicine for the treatment of skin disorders but it lacks proper pharmacological intervention. Citrus limetta Risso (Rutaceae) is an important commercial fruit crops used by juice processing industries in all continents. Ethnopharmacological validation of an essential oil isolated from its peels may play a key role in converting the fruit waste materials into therapeutic value added products. To evaluate the chemical and pharmacological (in-vitro and in-vivo) profile of essential oil isolated from Citrus limetta peels (Clp-EO) against skin inflammation for its ethnopharmacological validation. Hydro-distilled essential oil extracted from Citrus limetta peels (Clp-EO) was subjected to gas chromatography (GC) analysis for identification of essential oil constituents and its anti-inflammatory evaluation through in vitro and in vivo models. Chemical fingerprint of Clp-EO revealed the presence of monoterpene hydrocarbon and limonene is the major component. Pre-treatment of Clp-EO to the macrophages was able to inhibit the production of pro-inflammatory cytokines (TNF-α, IL-6, IL-1β) in LPS-induced inflammation as well as the production of reactive oxygen species (ROS) in H 2 O 2 -induced oxidative stress. In in-vivo study, topical application of Clp-EO was also able to reduce the 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear thickness, ear weight, lipid peroxidation, pro-inflammatory cytokines production and ameliorate the histological damage in the ear tissue. In-vitro and in-vivo toxicity study indicate that it is safe for topical application on skin. These findings suggested the preventive potential of Clp-EO for the treatment of inflammation linked skin diseases. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Evidence and Considerations in the Application of Chemical Peels in Skin Disorders and Aesthetic Resurfacing

    PubMed Central

    Berson, Diane S.; Cohen, Joel L.; Roberts, Wendy E.; Starker, Isaac; Wang, Beatrice

    2010-01-01

    Chemical peeling is a popular, relatively inexpensive, and generally safe method for treatment of some skin disorders and to refresh and rejuvenate skin. This article focuses on chemical peels and their use in routine clinical practice. Chemical peels are classified by the depth of action into superficial, medium, and deep peels. The depth of the peel is correlated with clinical changes, with the greatest change achieved by deep peels. However, the depth is also associated with longer healing times and the potential for complications. A wide variety of peels are available, utilizing various topical agents and concentrations, including a recent salicylic acid derivative, β-lipohydroxy acid, which has properties that may expand the clinical use of peels. Superficial peels, penetrating only the epidermis, can be used to enhance treatment for a variety of conditions, including acne, melasma, dyschromias, photodamage, and actinic keratoses. Medium-depth peels, penetrating to the papillary dermis, may be used for dyschromia, multiple solar keratoses, superficial scars, and pigmentary disorders. Deep peels, affecting reticular dermis, may be used for severe photoaging, deep wrinkles, or scars. Peels can be combined with other in-office facial resurfacing techniques to optimize outcomes and enhance patient satisfaction and allow clinicians to tailor the treatment to individual patient needs. Successful outcomes are based on a careful patient selection as well as appropriate use of specific peeling agents. Used properly, the chemical peel has the potential to fill an important therapeutic need in the dermatologist's and plastic surgeon's armamentarium. PMID:20725555

  19. Anticholinesterase and antioxidative properties of water-extractable phytochemicals from some citrus peels.

    PubMed

    Ademosun, Ayokunle Olubode; Oboh, Ganiyu

    2014-05-01

    Aqueous extracts from citrus peels are used in many rural communities in Nigeria in treating various degenerative conditions, although the scientific basis for its use has not been well established. This study sought to investigate the anticholinesterase and antioxidant properties of aqueous extracts from some citrus peels [orange (Citrus sinensis), grapefruit (Citrus paradisii), and shaddock (Citrus maxima)]. The effects of the extracts on acetylcholinesterase (AChE) activity, as well as Fe2+-induced malondialdehyde (MDA) production in vitro, were investigated. The total phenolic, flavonoid content, and antioxidant activities as typified by 1,1-diphenyl-2 picrylhydrazyl (DPPH) free radical scavenging ability and hydroxyl (OH) radicals scavenging abilities were also investigated. The results revealed that orange peels had the highest total phenol content followed by grapefruit peels, whereas shaddock peels had the least. The extracts inhibited AChE activity in a dose-dependent manner, although there is no significant difference (p>0.05) in their inhibitory abilities of the peels. The extracts exhibited antioxidant activities as typified by their radical (DPPH· and OH·) scavenging abilities as well as the inhibition of Fe2+-induced lipid peroxidation in rat's brain in vitro. The anticholinesterase activity and inhibition of MDA production by the aqueous extracts of the peels, as well as other antioxidant activities, could make the peels a good dietary means for the management of oxidative-mediated neurodegenerative disorders.

  20. Wrong postural hygiene and ergonomics in dental students of the University of Valencia (Spain) (part I).

    PubMed

    Cervera-Espert, J; Pascual-Moscardó, A; Camps-Alemany, I

    2018-02-01

    Failure to adopt a correct working posture can lead to occupational diseases. Evaluate knowledge in relation to ergonomics about BHOP concept and its application to routine clinical practice amongst undergraduate and postgraduate dental students in the University of Valencia (Valencia, Spain). A study based on interviews of undergraduate and postgraduate dental students in the University of Valencia (Valencia, Spain) was carried out. The information from a total of 336 interviews was used for the statistical analysis, differentiating according to gender and academic year: knowledge of ergonomics, pain prevalence and antecedents, assessment of the possible necessity for improved training in ergonomics, and evaluation of postural hygiene. Only 28.6% of the students were found to sit correctly in the dentist chair. Furthermore, in the opinion of the students, very few subjects during the career afforded adequate teaching in relation to ergonomics and working posture. The analysis of postural hygiene showed great variability. There were no significant differences in posture between males and females, although some incorrect postures appeared to be associated with the academic year (P<.05). However, no significant improvements in postural hygiene were noted on progressing from one academic year to the next. The students in our study were not familiar with the principles of ergonomics and did not sit correctly in the dentist chair. Improved training in this field is required in dental school. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Variability of arginine content and yield components in Valencia peanut germplasm.

    PubMed

    Aninbon, Chorkaew; Jogloy, Sanun; Vorasoot, Nimitr; Nuchadomrong, Suporn; Holbrook, C Corley; Kvien, Craig; Puppala, Naveen; Patanothai, Aran

    2017-06-01

    Peanut seeds are rich in arginine, an amino acid that has several positive effects on human health. Establishing the genetic variability of arginine content in peanut will be useful for breeding programs that have high arginine as one of their goals. The objective of this study was to evaluate the variation of arginine content, pods/plant, seeds/pod, seed weight, and yield in Valencia peanut germplasm. One hundred and thirty peanut genotypes were grown under field condition for two years. A randomized complete block design with three replications was used for this study. Arginine content was analyzed in peanut seeds at harvest using spectrophotometry. Yield and yield components were recorded for each genotype. Significant differences in arginine content and yield components were found in the tested Valencia peanut germplasm. Arginine content ranged from 8.68-23.35 μg/g seed. Kremena was the best overall genotype of high arginine content, number of pods/plant, 100 seed weight and pod yield.

  2. Thermal stability of liquid antioxidative extracts from pomegranate peel

    USDA-ARS?s Scientific Manuscript database

    This research was carried out to assess the potential of using the natural antioxidants in pomegranate peel extracts as replacement for synthetic antioxidants. As a result the thermal stability of pomegranate peel extract products during sterilization and storage, and its effect on industrial, color...

  3. Quantitative analysis of peel-off degree for printed electronics

    NASA Astrophysics Data System (ADS)

    Park, Janghoon; Lee, Jongsu; Sung, Ki-Hak; Shin, Kee-Hyun; Kang, Hyunkyoo

    2018-02-01

    We suggest a facile methodology of peel-off degree evaluation by image processing on printed electronics. The quantification of peeled and printed areas was performed using open source programs. To verify the accuracy of methods, we manually removed areas from the printed circuit that was measured, resulting in 96.3% accuracy. The sintered patterns showed a decreasing tendency in accordance with the increase in the energy density of an infrared lamp, and the peel-off degree increased. Thus, the comparison between both results was presented. Finally, the correlation between performance characteristics was determined by quantitative analysis.

  4. Biotechnological Potential of Agro-Industrial Wastes as a Carbon Source to Thermostable Polygalacturonase Production in Aspergillus niveus.

    PubMed

    Maller, Alexandre; Damásio, André Ricardo Lima; da Silva, Tony Marcio; Jorge, João Atílio; Terenzi, Héctor Francisco; Polizeli, Maria de Lourdes Teixeira de Moraes

    2011-01-01

    Agro-industrial wastes are mainly composed of complex polysaccharides that might serve as nutrients for microbial growth and production of enzymes. The aim of this work was to study polygalacturonase (PG) production by Aspergillus niveus cultured on liquid or solid media supplemented with agro-industrial wastes. Submerged fermentation (SbmF) was tested using Czapeck media supplemented with 28 different carbon sources. Among these, orange peel was the best PG inducer. On the other hand, for solid state fermentation (SSF), lemon peel was the best inducer. By comparing SbmF with SSF, both supplemented with lemon peel, it was observed that PG levels were 4.4-fold higher under SSF. Maximum PG activity was observed at 55°C and pH 4.0. The enzyme was stable at 60°C for 90 min and at pH 3.0-5.0. The properties of this enzyme, produced on inexpensive fermentation substrates, were interesting and suggested several biotechnological applications.

  5. Valencia College, No. 1 Nationwide: It's All about "Student Experience"

    ERIC Educational Resources Information Center

    Adam, Michelle

    2012-01-01

    Twelve years ago, Sanford Shugart took the helm at Valencia College. This school of 70,000-plus students in Orlando, FL, seemed like any other community college, but Shugart's reason for being there, and the change this college was about to undergo, was anything but ordinary. Before his arrival, the school had begun a process called Campus…

  6. Cyanogenic potential of cassava peels and their detoxification for utilization as livestock feed.

    PubMed

    Tweyongyere, Robert; Katongole, Ignatious

    2002-12-01

    This study determined the cyanogenic potential of the cassava peels and assess the effectiveness of sun drying, heap fermentation and wet fermentation (soaking) in reducing the cyanide potential of the peels. Fresh cassava peels from major fresh food markets in Kampala and cassava grown in various parts of Uganda from Namolonge Agricultural and Animal Research Institute were used. The fresh peels from the market were subjected to the different detoxification methods foe 5 d; the cyanide potential was determined by enzymatic assay. The mean potential of the cassava peels from the food markets Kampala was 856 mg cyanide equivalen/kg of dry matter. The potential of the peels of the 14 cultivars fell between 253 and 1081 mg cyanide eQuivalent/kg of dry matter. High cyanogenic potential cultivars dominate on the market and pose danger of poisoning to livestock fed on fresh cassava peels. Treatment of the peels by sun-drying, heap fermentation on soaking reduced the cyanide potential to below 100 mg cyanide equivalent/kg of dry matter at 48, 72 and 96 h respectively. Sun-dying caused an early sharp fall in the cyanide potential, but heap fermentation or soaking gave the lowest residual cyanide after 120 h. Cassava peels could be safely used as livestock feed if they are treated to reduce the cyanogenic potential.

  7. The X-point effects on the peeling-ballooning stability conditions

    NASA Astrophysics Data System (ADS)

    Zheng, Linjin

    2017-10-01

    Due to the X-point singularity the safety factor tends to infinity as the last closed flux surface is approached. The usual numerical treatment of X-point singularity is to cut off a small fraction of edge region for system stability evaluation or simply use an up-down symmetric equilibrium without X-point included. This type of treatments have been used to make the peeling-ballooning stability diagram. We found that the mode types, peel or ballooning, can vary depending on how much the edge portion is cut off. When the cutting-off leads the edge safety factor (qa) to become close to a mode rational number, the peeling modes dominate; otherwise the ballooning type of modes prevail. The stability condition for peeling modes with qa being close to a rational number is much stringent than that for ballooning type of modes. Because qa tends to infinite near the separatrix, the mode rational surfaces are concentrated in the plasma region and thus the peeling modes are basically excluded. This extrapolation indicates that the stability boundary for high edge current, which is related to the peeling modes, need to be reexamined to take into account the X-point effects. Supported by U. S. Department of Energy, Office of Fusion Energy Science: Grant No. DE-FG02-04ER-54742.

  8. Anti-inflammatory and antioxidant activities of extracts from Musa sapientum peel.

    PubMed

    Phuaklee, Pathompong; Ruangnoo, Srisopa; Itharat, Arunporn

    2012-01-01

    Many parts of Musa sapientum Linn. (Musaceae) are used in Thai traditional medicine as drugs, food supplements and cosmetics. The banana peel is used as an astringent in foot care, the unripe fruit is used to treat diarrhea and, the ripe fruit is used as tonic. To evaluate anti-inflammatory and antioxidant activities of banana peel extracts obtained from different extraction methods and to determine their total phenolic content. Four extraction methods were used to extract unripe and ripe peels. Nitric oxide inhibitory and DPPH scavenging assays were used to evaluate anti-inflammatory and antioxidant activities, respectively. Folin-Ciocalteu's reagent was used to determine total phenolic content. The water extract of fresh ripe peel exhibited the most potent NO inhibitory activity (IC50 = 6.68 +/- 0.34 microg/ml), but apparently exhibited no antioxidant activity. The decoction extract of fresh unripe peel exhibited strong antioxidant activity as well as had the highest total phenolic compound. The antioxidant activity exhibited a correlation with the total phenolic content. This study supports the use of Musa sapientum peel in Thai Traditional Medicine for treatment of inflammatory-related diseases.

  9. [Mass Transfer Kinetics Model of Ultrasonic Extraction of Pomegranate Peel Polyphenols].

    PubMed

    Wang, Zhan-yi; Zhang, Li-hua; Wang, Yu-hai; Zhang, Yuan-hu; Ma, Li; Zheng, Dan-dan

    2015-05-01

    The dynamic mathematical model of ultrasonic extraction of polyphenols from pomegranate peel was constructed with the Fick's second law as the theoretical basis. The spherical model was selected, with mass concentrations of pomegranate peel polyphenols as the index, 50% ethanol as the extraction solvent and ultrasonic extraction as the extraction method. In different test conditions including the liquid ratio, extraction temperature and extraction time, a series of kinetic parameters were solved, such as the extraction process (k), relative raffinate rate, surface diffusion coefficient(D(S)), half life (t½) and the apparent activation energy (E(a)). With the extraction temperature increasing, k and D(S) were gradually increased with t½ decreasing,which indicated that the elevated temperature was favorable to the extraction of pomegranate peel polyphenols. The exponential equation of relative raffinate rate showed that the established numerical dynamics model fitted the extraction of pomegranate peel polyphenols, and the relationship between the reaction conditions and pomegranate peel polyphenols concentration was well reflected by the model. Based on the experimental results, a feasible and reliable kinetic model for ultrasonic extraction of polyphenols from pomegranate peel is established, which can be used for the optimization control of engineering magnifying production.

  10. Water-Based Peeling of Thin Hydrophobic Films

    NASA Astrophysics Data System (ADS)

    Khodaparast, Sepideh; Boulogne, François; Poulard, Christophe; Stone, Howard A.

    2017-10-01

    Inks of permanent markers and waterproof cosmetics create elastic thin films upon application on a surface. Such adhesive materials are deliberately designed to exhibit water-repellent behavior. Therefore, patterns made up of these inks become resistant to moisture and cannot be cleaned by water after drying. However, we show that sufficiently slow dipping of such elastic films, which are adhered to a substrate, into a bath of pure water allows for complete removal of the hydrophobic coatings. Upon dipping, the air-water interface in the bath forms a contact line on the substrate, which exerts a capillary-induced peeling force at the edge of the hydrophobic thin film. We highlight that this capillary peeling process is more effective at lower velocities of the air-liquid interface and lower viscosities. Capillary peeling not only removes such thin films from the substrate but also transfers them flawlessly onto the air-water interface.

  11. Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin.

    PubMed

    Oresajo, Christian; Yatskayer, Margarita; Hansenne, Isabelle

    2008-12-01

    Several chemical agents are currently used to perform superficial peels of the face to reduce facial hyperpigmentation and fine lines/wrinkles. Some of the most commonly used agents are alpha hydroxyl acids, such as glycolic acid (GA), or beta hydroxy acid, such as salicylic acid. This study aims to compare the efficacy of GA to that of a novel derivative of salicylic acid, capryloyl salicylic acid (LHA). In a split-face study, 50 female volunteers between the ages of 35 and 60 years with mild to moderate facial hyperpigmentation and fine lines/wrinkles were randomized and LHA or GA peel was applied to one side of the face. Increasing peel concentrations were applied (5-10% LHA or 20-50% GA) based on the tolerance level of the subjects and clinical observations of an expert dermatologist for 12 weeks at biweekly intervals. Of the 44 volunteers who completed the study, at 12 weeks 41% of LHA-treated and 30% of GA-treated subjects demonstrated significant reduction of fine lines/wrinkles compared to baseline. Forty-six percent of LHA-treated subjects and 34% of GA-treated subjects showed significant reduction of hyperpigmentation compared to baseline. LHA treatment was better than GA peels, although there were no statistically significant differences between the two groups. Five percent to 10% of LHA peel is generally safe and as effective as 20-50% GA peel in reducing facial hyperpigmentation and fine lines/wrinkles.

  12. Micro-scale anaerobic digestion of point source components of organic fraction of municipal solid waste

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chanakya, H.N.; Sharma, Isha; Ramachandra, T.V.

    The fermentation characteristics of six specific types of the organic fraction of municipal solid waste (OFMSW) were examined, with an emphasis on properties that are needed when designing plug-flow type anaerobic bioreactors. More specifically, the decomposition patterns of a vegetable (cabbage), fruits (banana and citrus peels), fresh leaf litter of bamboo and teak leaves, and paper (newsprint) waste streams as feedstocks were studied. Individual OFMSW components were placed into nylon mesh bags and subjected to various fermentation periods (solids retention time, SRT) within the inlet of a functioning plug-flow biogas fermentor. These were removed at periodic intervals, and their compositionmore » was analyzed to monitor decomposition rates and changes in chemical composition. Components like cabbage waste, banana peels, and orange peels fermented rapidly both in a plug-flow biogas reactor (PFBR) as well as under a biological methane potential (BMP) assay, while other OFMSW components (leaf litter from bamboo and teak leaves and newsprint) fermented slowly with poor process stability and moderate biodegradation. For fruit and vegetable wastes (FVW), a rapid and efficient removal of pectins is the main cause of rapid disintegration of these feedstocks, which left behind very little compost forming residues (2-5%). Teak and bamboo leaves and newsprint decomposed only to 25-50% in 30 d. These results confirm the potential for volatile fatty acids accumulation in a PFBR's inlet and suggest a modification of the inlet zone or operation of a PFBR with the above feedstocks.« less

  13. Micro-scale anaerobic digestion of point source components of organic fraction of municipal solid waste.

    PubMed

    Chanakya, H N; Sharma, Isha; Ramachandra, T V

    2009-04-01

    The fermentation characteristics of six specific types of the organic fraction of municipal solid waste (OFMSW) were examined, with an emphasis on properties that are needed when designing plug-flow type anaerobic bioreactors. More specifically, the decomposition patterns of a vegetable (cabbage), fruits (banana and citrus peels), fresh leaf litter of bamboo and teak leaves, and paper (newsprint) waste streams as feedstocks were studied. Individual OFMSW components were placed into nylon mesh bags and subjected to various fermentation periods (solids retention time, SRT) within the inlet of a functioning plug-flow biogas fermentor. These were removed at periodic intervals, and their composition was analyzed to monitor decomposition rates and changes in chemical composition. Components like cabbage waste, banana peels, and orange peels fermented rapidly both in a plug-flow biogas reactor (PFBR) as well as under a biological methane potential (BMP) assay, while other OFMSW components (leaf litter from bamboo and teak leaves and newsprint) fermented slowly with poor process stability and moderate biodegradation. For fruit and vegetable wastes (FVW), a rapid and efficient removal of pectins is the main cause of rapid disintegration of these feedstocks, which left behind very little compost forming residues (2-5%). Teak and bamboo leaves and newsprint decomposed only to 25-50% in 30d. These results confirm the potential for volatile fatty acids accumulation in a PFBR's inlet and suggest a modification of the inlet zone or operation of a PFBR with the above feedstocks.

  14. Alpha-hydroxyacid chemical peeling agents: case studies and rationale for safe and effective use.

    PubMed

    Briden, M Elizabeth

    2004-02-01

    Chemical peeling is an in-office procedure that involves the application of a chemical agent to the skin to induce controlled destruction or exfoliation of old skin and stimulation of new epidermal growth with more evenly distributed melanin. When peel agents reach the dermal layer, important wound-healing activities occur that cause skin remodeling and skin smoothing, both antiaging benefits. There are a number of key factors in selecting a peeling agent and procedure, and each is discussed. Variables to consider are the peeling agent and its formulation, the concentration of the agent, the patient's skin type, the site to be peeled, the skin preparation procedure prior to and immediately preceding the application of the agent, the application method, the duration of contact, and the patient's medical history and lifestyle. Various types of peels are discussed. Of particular interest are superficial chemical peels, which offer great flexibility over a range of skin types and conditions with minimal to no "downtime." Alpha-hydroxyacid (AHA) peels are superficial and can be combined with other cosmetic procedures in the office to maximize benefits. In addition, AHA peels work well when combined with supportive homecare products including AHAs or polyhydroxy acids (PHAs), topical retinoids, and antiacne/antirosacea treatments. Case studies are presented of patients using AHA peels for the treatment of acne and hyperpigmentation in a variety of skin types, including Asian skin.

  15. Internal Limiting Membrane Peeling to Prevent Post-vitrectomy Epiretinal Membrane Development in Retinal Detachment.

    PubMed

    Akiyama, Kunihiko; Fujinami, Kaoru; Watanabe, Ken; Tsunoda, Kazushige; Noda, Toru

    2016-11-01

    To determine the efficacy of internal limiting membrane (ILM) peeling during vitrectomy for rhegmatogenous retinal detachment (RRD) regarding post-vitrectomy epiretinal membrane (ERM) development and visual outcomes. Retrospective, interventional, comparative case series. Setting: Institutional. One hundred and two consecutive eyes with RRD treated with vitrectomy and followed for at least 6 months. ILM was peeled without using dye such as indocyanine green (ICG). Observational Procedures: Patients were divided into 2 groups based on postoperative ERM development: Group 1, 81 eyes without ERM formation; Group 2, 21 eyes with ERM development. Patients also were divided into 2 subgroups: those with and without ILM peeling (58 and 44 eyes, respectively). Statistical analyses were performed between the 2 groups with/without ERM formation and between the 2 subgroups with/without ILM peeling for 5 preoperative factors including foveal involvement of the RRD, 4 intraoperative factors including ILM peeling, baseline best-corrected visual acuity (BCVA), and final BCVA. An association of ILM peeling with ERM prevention and the influence of ILM peeling on visual outcomes. ILM peeling was significantly (P < .001) associated with ERM prevention. There was no significant difference in the final BCVA between subgroups with and without ILM peeling. ILM peeling without ICG staining during the initial vitrectomy for RRDs may prevent postoperative ERM formation with favorable visual outcomes. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Production of xylanase and protease by Penicillium janthinellum CRC 87M-115 from different agricultural wastes.

    PubMed

    Oliveira, Luciana A; Porto, Ana L F; Tambourgi, Elias B

    2006-04-01

    Five agricultural wastes were evaluated in submerged fermentation for xylanolytic enzymes production by Penicillium janthinellum. The wastes were hydrolyzed in acid medium and the liquid fraction was used for cultivation. Corn cob (55.3 U/mL) and oat husk (54.8 U/mL) were the best inducers of xylanase. Sugar cane bagasse (23.0 U/mL) and corn husk (23.8 U/mL) were moderately good, while cassava peel was negligible. Protease production was very low in all agro-industrial residues. The maximum biomass yields were 1.30 and 1.17 g/L for cassava peel and corn husk after 180 h, respectively. Xylanolytic activity showed a cell growth associated profile.

  17. Dietary fibre components and pectin chemical features of peels during ripening in banana and plantain varieties.

    PubMed

    Happi Emaga, Thomas; Robert, Christelle; Ronkart, Sébastien N; Wathelet, Bernard; Paquot, Michel

    2008-07-01

    The effects of the ripeness stage of banana (Musa AAA) and plantain (Musa AAB) peels on neutral detergent fibre, acid detergent fibre, cellulose, hemicelluloses, lignin, pectin contents, and pectin chemical features were studied. Plantain peels contained a higher amount of lignin but had a lower hemicellulose content than banana peels. A sequential extraction of pectins showed that acid extraction was the most efficient to isolate banana peel pectins, whereas an ammonium oxalate extraction was more appropriate for plantain peels. In all the stages of maturation, the pectin content in banana peels was higher compared to plantain peels. Moreover, the galacturonic acid and methoxy group contents in banana peels were higher than in plantain peels. The average molecular weights of the extracted pectins were in the range of 132.6-573.8 kDa and were not dependant on peel variety, while the stage of maturation did not affect the dietary fibre yields and the composition in pectic polysaccharides in a consistent manner. This study has showed that banana peels are a potential source of dietary fibres and pectins.

  18. Clinical outcomes of double staining and additional ILM peeling during ERM surgery.

    PubMed

    Oh, Ha Na; Lee, Joo Eun; Kim, Hyun Woong; Yun, Il Han

    2013-08-01

    To assess the clinical outcomes in idiopathic epiretinal membrane (ERM) patients after vitrectomy and ERM removal with or without additional indocyanine green (ICG)-assisted internal limiting membrane (ILM) peeling. The medical records of 43 patients with an idiopathic ERM that underwent vitrectomy and ERM removal between July 2007 and April 2010 were reviewed. The patients were divided into two groups: triamcinolone-assisted simple ERM peeling only (group A, n = 23) and triamcinolone-assisted ERM peeling followed by ICG staining and peeling of the remaining internal ILM (group B, n = 20). No difference was found between the two groups in terms of visual acuity, macular thickness, P1 amplitude or implicit time on multifocal-electroretinogram (mfERG) at six and 12 months postoperatively. In group B, ICG staining after ERM peeling demonstrated that the ILM had been removed together with the ERM in 12 eyes (60%), and all 12 eyes showed punctate retinal hemorrhages during ERM peeling. There was no recurrence of an ERM in either group. Additional procedures involving ICG staining and ILM peeling during ERM surgery do not appear to have an additive effect on the clinical outcomes in terms of visual acuity, retinal function based on mfERG, or recurrence rate.

  19. Peel-and-Stick: Fabricating Thin Film Solar Cell on Universal Substrates

    PubMed Central

    Lee, Chi Hwan; Kim, Dong Rip; Cho, In Sun; William, Nemeth; Wang, Qi; Zheng, Xiaolin

    2012-01-01

    Fabrication of thin-film solar cells (TFSCs) on substrates other than Si and glass has been challenging because these nonconventional substrates are not suitable for the current TFSC fabrication processes due to poor surface flatness and low tolerance to high temperature and chemical processing. Here, we report a new peel-and-stick process that circumvents these fabrication challenges by peeling off the fully fabricated TFSCs from the original Si wafer and attaching TFSCs to virtually any substrates regardless of materials, flatness and rigidness. With the peel-and-stick process, we integrated hydrogenated amorphous silicon (a-Si:H) TFSCs on paper, plastics, cell phone and building windows while maintaining the original 7.5% efficiency. The new peel-and-stick process enables further reduction of the cost and weight for TFSCs and endows TFSCs with flexibility and attachability for broader application areas. We believe that the peel-and-stick process can be applied to thin film electronics as well. PMID:23277871

  20. Peel-and-Stick: Fabricating Thin Film Solar Cell on Universal Substrates

    NASA Astrophysics Data System (ADS)

    Lee, Chi Hwan; Kim, Dong Rip; Cho, In Sun; William, Nemeth; Wang, Qi; Zheng, Xiaolin

    2012-12-01

    Fabrication of thin-film solar cells (TFSCs) on substrates other than Si and glass has been challenging because these nonconventional substrates are not suitable for the current TFSC fabrication processes due to poor surface flatness and low tolerance to high temperature and chemical processing. Here, we report a new peel-and-stick process that circumvents these fabrication challenges by peeling off the fully fabricated TFSCs from the original Si wafer and attaching TFSCs to virtually any substrates regardless of materials, flatness and rigidness. With the peel-and-stick process, we integrated hydrogenated amorphous silicon (a-Si:H) TFSCs on paper, plastics, cell phone and building windows while maintaining the original 7.5% efficiency. The new peel-and-stick process enables further reduction of the cost and weight for TFSCs and endows TFSCs with flexibility and attachability for broader application areas. We believe that the peel-and-stick process can be applied to thin film electronics as well.

  1. Recovery of steroidal alkaloids from potato peels using pressurized liquid extraction.

    PubMed

    Hossain, Mohammad B; Rawson, Ashish; Aguiló-Aguayo, Ingrid; Brunton, Nigel P; Rai, Dilip K

    2015-05-13

    A higher yield of glycoalkaloids was recovered from potato peels using pressurized liquid extraction (1.92 mg/g dried potato peels) compared to conventional solid-liquid extraction (0.981 mg/g dried potato peels). Response surface methodology deduced the optimal temperature and extracting solvent (methanol) for the pressurized liquid extraction (PLE) of glycoalkaloids as 80 °C in 89% methanol. Using these two optimum PLE conditions, levels of individual steroidal alkaloids obtained were of 597, 873, 374 and 75 µg/g dried potato peel for α-solanine, α-chaconine, solanidine and demissidine respectively. Corresponding values for solid liquid extraction were 59%, 46%, 40% and 52% lower for α-solanine, α-chaconine, solanidine and demissidine respectively.

  2. Characterization of peeling modes in a low aspect ratio tokamak

    NASA Astrophysics Data System (ADS)

    Bongard, M. W.; Thome, K. E.; Barr, J. L.; Burke, M. G.; Fonck, R. J.; Hinson, E. T.; Redd, A. J.; Schlossberg, D. J.

    2014-11-01

    Peeling modes are observed at the plasma edge in the Pegasus Toroidal Experiment under conditions of high edge current density (Jedge ˜ 0.1 MA m-2) and low magnetic field (B ˜ 0.1 T) present at near-unity aspect ratio. Their macroscopic properties are measured using external Mirnov coil arrays, Langmuir probes and high-speed visible imaging. The modest edge parameters and short pulse lengths of Pegasus discharges permit direct measurement of the internal magnetic field structure with an insertable array of Hall-effect sensors, providing the current profile and its temporal evolution. Peeling modes generate coherent, edge-localized electromagnetic activity with low toroidal mode numbers n ⩽ 3 and high poloidal mode numbers, in agreement with theoretical expectations of a low-n external kink structure. Coherent MHD fluctuation amplitudes are found to be strongly dependent on the experimentally measured Jedge/B peeling instability drive, consistent with theory. Peeling modes nonlinearly generate ELM-like, field-aligned filamentary structures that detach from the edge and propagate radially outward. The KFIT equilibrium code is extended with an Akima spline profile parameterization and an improved model for induced toroidal wall current estimation to obtain a reconstruction during peeling activity with its current profile constrained by internal Hall measurements. It is used to test the analytic peeling stability criterion and numerically evaluate ideal MHD stability. Both approaches predict instability, in agreement with experiment, with the latter identifying an unstable external kink.

  3. Efficacy of combination of glycolic acid peeling with topical regimen in treatment of melasma.

    PubMed

    Chaudhary, Savita; Dayal, Surabhi

    2013-10-01

    Various treatment modalities are available for management of melasma, ranging from topical and oral to chemical peeling, but none is promising alone. Very few studies are available regarding efficacy of combination of topical treatment with chemical peeling. Combination of chemical peeling and topical regimen can be a good treatment modality in the management of this recalcitrant disorder. To assess the efficacy of combination of topical regimen (2% hydroquinone, 1% hydrocortisone and 0.05% tretinoin) with serial glycolic acid peeling in the treatment of melasma in Indian patients. Forty Indian patients of moderate to severe epidermal variety melasma were divided into two groups of 20 each. One Group i.e. peel group received topical regimen (2% hydroquinone, 1% hydrocortisone and 0.05% tretinoin) with serial glycolic acid peeling and other group i.e. control group received topical regimen (2% hydroquinone, 1% hydrocortisone, 0.05% tretinoin). There was an overall decrease in MASI from baseline in 24 weeks of therapy in both the groups (P value < 0.05). The group receiving the glycolic acid peel with topical regimen showed early and greater improvement than the group which was receiving topical regimen only. This study concluded that combining topical regimen (2% hydroquinone, 1% hydrocortisone and 0.05% tretinoin) with serial glycolic acid peeling significantly enhances the therapeutic efficacy of glycolic acid peeling. The combination of glycolic acid peeling with the topical regimen is a highly effective, safe and promising therapeutic option in treatment of melasma.

  4. Cross-validation and Peeling Strategies for Survival Bump Hunting using Recursive Peeling Methods

    PubMed Central

    Dazard, Jean-Eudes; Choe, Michael; LeBlanc, Michael; Rao, J. Sunil

    2015-01-01

    We introduce a framework to build a survival/risk bump hunting model with a censored time-to-event response. Our Survival Bump Hunting (SBH) method is based on a recursive peeling procedure that uses a specific survival peeling criterion derived from non/semi-parametric statistics such as the hazards-ratio, the log-rank test or the Nelson--Aalen estimator. To optimize the tuning parameter of the model and validate it, we introduce an objective function based on survival or prediction-error statistics, such as the log-rank test and the concordance error rate. We also describe two alternative cross-validation techniques adapted to the joint task of decision-rule making by recursive peeling and survival estimation. Numerical analyses show the importance of replicated cross-validation and the differences between criteria and techniques in both low and high-dimensional settings. Although several non-parametric survival models exist, none addresses the problem of directly identifying local extrema. We show how SBH efficiently estimates extreme survival/risk subgroups unlike other models. This provides an insight into the behavior of commonly used models and suggests alternatives to be adopted in practice. Finally, our SBH framework was applied to a clinical dataset. In it, we identified subsets of patients characterized by clinical and demographic covariates with a distinct extreme survival outcome, for which tailored medical interventions could be made. An R package PRIMsrc (Patient Rule Induction Method in Survival, Regression and Classification settings) is available on CRAN (Comprehensive R Archive Network) and GitHub. PMID:27034730

  5. Separation and characterization of polyphenolics from underutilized byproducts of fruit production (Choerospondias axillaris peels): inhibitory activity of proanthocyanidins against glycolysis enzymes.

    PubMed

    Li, Qian; Chen, Jun; Li, Ti; Liu, Chengmei; Zhai, Yuxin; McClements, David Julian; Liu, Jiyan

    2015-12-01

    Bioactive proanthocyanidins were isolated from the peel of Choerospondias axillaris fruit, which is a waste product of the food processing industry. Compositional analysis indicated that the proanthocyanidins had extension units mainly consisting of epicatechin gallate or epicatechin, and terminal units mainly consisting of catechin. Numerous polymeric forms of the molecules were detected, including monomers, dimers, and trimers. Certain fractions exhibited strong α-amylase or α-glucosidase inhibition in a dose-dependent manner. Furthermore, their inhibitory activities depended on their degree of polymerization and galloylation. For example, the most bioactive fraction had α-amylase and α-glucosidase inhibitory activities (IC50 values) of 541 and 3.1 μg mL(-1), respectively. This study demonstrates that proanthocyanidins from C. axillaris peels can inhibit carbohydrate digestive enzymes in vitro and may therefore serve as antidiabetic ingredients in functional or medical foods.

  6. Analysis of Biomethanation Process from market waste to generate bio energy

    NASA Astrophysics Data System (ADS)

    Sathish, S.; Parthiban, A.; Vinod kumar, T.; Chandrasekaran, M.

    2017-03-01

    In this study was to incur that the biogas production from traditional market wastes which were represented by cabbage stem and carrot peeling, white mustard were under taken in a laboratory experiment. To produce biogas, the raw material such as cabbage stem and carrot peeling, white mustard and carrot peeling were mixed until C/N ratio close 30:1. Inoculums starter cow dung is put into digester then water is added until 500 liters. The initial pH is measured at throughout the experiments. The anaerobic digestion process is conducted at temperature of 30ºC and the volumes, pH of the biogas yield were observed daily. Biogas yield and cumulative biogas, total solids were analyzed 35 days. The cumulative biogas yield at the 32th day of digestion for cabbage stem and carrot peeling (exp1), white mustard and carrot peeling (exp2) were 2140 liters and 2421 liters respectively. The highest daily biogas yield is achieved on the 22st day of digestion which is found 123 liters and 141 liters respectively. In the first 10 days, the pH level is observed decrease and increase after the day of 21. Although at the end of digestion period the pH will fall down.

  7. Ammonia nitrogen removal from aqueous solution by local agricultural wastes

    NASA Astrophysics Data System (ADS)

    Azreen, I.; Lija, Y.; Zahrim, A. Y.

    2017-06-01

    Excess ammonia nitrogen in the waterways causes serious distortion to environment such as eutrophication and toxicity to aquatic organisms. Ammonia nitrogen removal from synthetic solution was investigated by using 40 local agricultural wastes as potential low cost adsorbent. Some of the adsorbent were able to remove ammonia nitrogen with adsorption capacity ranging from 0.58 mg/g to 3.58 mg/g. The highest adsorption capacity was recorded by Langsat peels with 3.58 mg/g followed by Jackfruit seeds and Moringa peels with 3.37 mg/g and 2.64 mg/g respectively. This experimental results show that the agricultural wastes can be utilized as biosorbent for ammonia nitrogen removal. The effect of initial ammonia nitrogen concentration, pH and stirring rate on the adsorption process were studied in batch experiment. The adsorption capacity reached maximum value at pH 7 with initial concentration of 500 mg/L and the removal rate decreased as stirring rate was applied.

  8. Damage and recovery of skin barrier function after glycolic acid chemical peeling and crystal microdermabrasion.

    PubMed

    Song, Ji Youn; Kang, Hyun A; Kim, Mi-Yeon; Park, Young Min; Kim, Hyung Ok

    2004-03-01

    Superficial chemical peeling and microdermabrasion have become increasingly popular methods for producing facial rejuvenation. However, there are few studies reporting the skin barrier function changes after these procedures. To evaluate objectively the degree of damage visually and the time needed for the skin barrier function to recover after glycolic acid peeling and aluminum oxide crystal microdermabrasion using noninvasive bioengineering methods. Superficial chemical peeling using 30%, 50%, and 70% glycolic acid and aluminum oxide crystal microdermabrasion were used on the volar forearm of 13 healthy women. The skin response was measured by a visual observation and using an evaporimeter, corneometer, and colorimeter before and after peeling at set time intervals. Both glycolic acid peeling and aluminum oxide crystal microdermabrasion induced significant damage to the skin barrier function immediately after the procedure, and the degree of damage was less severe after the aluminum oxide crystal microdermabrasion compared with glycolic acid peeling. The damaged skin barrier function had recovered within 24 hours after both procedures. The degree of erythema induction was less severe after the aluminum oxide crystal microdermabrasion compared with the glycolic acid peeling procedure. The degree of erythema induced after the glycolic acid peeling procedure was not proportional to the peeling solution concentration used. The erythema subsided within 1 day after the aluminum oxide crystal microdermabrasion procedure and within 4 days after the glycolic acid peeling procedure. These results suggest that the skin barrier function is damaged after the glycolic acid peeling and aluminum oxide crystal microdermabrasion procedure but recovers within 1 to 4 days. Therefore, repeating the superficial peeling procedure at 2-week intervals will allow sufficient time for the damaged skin to recover its barrier function.

  9. [Prevalence of indirect sharing of drug-injecting paraphernalia in Galicia, Madrid, Seville and Valencia [Spain

    PubMed

    Bravo, María J; Royuela, Luis; Barrio, Gregorio; Rodríguez-Arenas, María A; de la Fuente, Luis

    2004-01-01

    To study drug-injecting practices, particularly indirect sharing of injecting paraphernalia (ISIP), and sexual risk behavior. We performed a cross-sectional study of 1638 users of needle exchange programs (NEPs). Different types of ISIP were studied: taking diluted drugs in a syringe used by others, placing the needle in a recipient with other used needles, and reusing cleaning liquid previously used by others. The prevalence of injecting with syringes already used by others was 16% in Galicia, 4.7% in Madrid, 17.6% in Seville and 13.2% in Valencia (p < 0.001). With geographical variations, other types of ISIP (Galicia: 32.4%; Madrid: 28.5%; Seville: 42.6%; Valencia: 27.4% -p < 0.001-) were more frequent than injecting with syringes already used by others (Galicia: 32.4%; Madrid: 28.5%; Seville: 42.6%; Valencia: 27.4% -p < 0.001-). The percentage not injecting with syringes used by others but performing ISIP was 21.7%, 25.3%, 28.2% and 18.1% (p < 0.01) respectively. In all geographical areas, sexual risk practices were more prevalent with steady sex partners (68.6%, 72.0%, 77.8%, 72.8% [NS]) than with casual partners (36.6%, 40.9%, 37.9%, 23.9% [NS]). Among injectors with a stable partner, 81.3% in Galicia, 75.9% in Madrid, 86.1% in Seville and 79.7% in Valencia reported that his/her serological status was negative for HIV or was unknown (p < 0.001). ISIP is more prevalent than injection with syringes already used by others. For a substantial percentage of injectors, ISIP is the only risk practice. ISIP and the low use of condoms, particularly with steady partners, could be a contributory factor to the spread of HIV, hepatitis C virus, and hepatitis B virus infection.

  10. Risk assessment and monitoring programme of nitrates through vegetables in the Region of Valencia (Spain).

    PubMed

    Quijano, Leyre; Yusà, Vicent; Font, Guillermina; McAllister, Claudia; Torres, Concepción; Pardo, Olga

    2017-02-01

    This study was carried out to determine current levels of nitrate in vegetables marketed in the Region of Valencia (Spain) and to estimate the toxicological risk associated with their intake. A total of 533 samples of seven vegetable species were studied. Nitrate levels were derived from the Valencia Region monitoring programme carried out from 2009 to 2013 and food consumption levels were taken from the first Valencia Food Consumption Survey, conducted in 2010. The exposure was estimated using a probabilistic approach and two scenarios were assumed for left-censored data: the lower-bound scenario, in which unquantified results (below the limit of quantification) were set to zero and the upper-bound scenario, in which unquantified results were set to the limit of quantification value. The exposure of the Valencia consumers to nitrate through the consumption of vegetable products appears to be relatively low. In the adult population (16-95 years) the P99.9 was 3.13 mg kg -1 body weight day -1 and 3.15 mg kg -1 body weight day -1 in the lower bound and upper bound scenario, respectively. On the other hand, for young people (6-15 years) the P99.9 of the exposure was 4.20 mg kg -1 body weight day -1 and 4.40 mg kg -1 body weight day -1 in the lower bound and upper bound scenario, respectively. The risk characterisation indicates that, under the upper bound scenario, 0.79% of adults and 1.39% of young people can exceed the Acceptable Daily Intake of nitrate. This percentage could join the vegetable extreme consumers (such as vegetarians) of vegetables. Overall, the estimated exposures to nitrate from vegetables are unlikely to result in appreciable health risks. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Retinal thickness after vitrectomy and internal limiting membrane peeling for macular hole and epiretinal membrane

    PubMed Central

    Kumagai, Kazuyuki; Ogino, Nobuchika; Furukawa, Mariko; Hangai, Masanori; Kazama, Shigeyasu; Nishigaki, Shirou; Larson, Eric

    2012-01-01

    Purpose To determine the retinal thickness (RT), after vitrectomy with internal limiting membrane (ILM) peeling, for an idiopathic macular hole (MH) or an epiretinal membrane (ERM). Also, to investigate the effect of a dissociated optic nerve fiber layer (DONFL) appearance on RT. Methods A non-randomized, retrospective chart review was performed for 159 patients who had successful closure of a MH, with (n = 148), or without (n = 11), ILM peeling. Also studied were 117 patients who had successful removal of an ERM, with (n = 104), or without (n = 13), ILM peeling. The RT of the nine Early Treatment Diabetic Retinopathy Study areas was measured by spectral domain optical coherence tomography (SD-OCT). In the MH-with-ILM peeling and ERM-with-ILM peeling groups, the RT of the operated eyes was compared to the corresponding areas of normal fellow eyes. The inner temporal/inner nasal ratio (TNR) was used to assess the effect of ILM peeling on RT. The effects of DONFL appearance on RT were evaluated in only the MH-with-ILM peeling group. Results In the MH-with-ILM peeling group, the central, inner nasal, and outer nasal areas of the retina of operated eyes were significantly thicker than the corresponding areas of normal fellow eyes. In addition, the inner temporal, outer temporal, and inner superior retina was significantly thinner than in the corresponding areas of normal fellow eyes. Similar findings were observed regardless of the presence of a DONFL appearance. In the ERM-with-ILM peeling group, the retina of operated eyes was significantly thicker in all areas, except the inner and outer temporal areas. In the MH-with-ILM peeling group, the TNR was 0.86 in operated eyes, and 0.96 in fellow eyes (P < 0.001). In the ERM-with-ILM peeling group, the TNR was 0.84 in operated eyes, and 0.95 in fellow eyes (P < 0.001). TNR in operated eyes of the MH-without-ILM peeling group was 0.98, which was significantly greater than that of the MH-with-ILM peeling group (P < 0

  12. Killing Unwanted West Indies Mahogany Trees by Peeling and Frilling

    Treesearch

    R. W. Nobles; C. B. Briscoe

    1966-01-01

    Peeling and frilling each killed approximately 70 percent of treated West Indies mahogany, but peeling killed a higher percentage of trees between 18 and 33 centimeters (7 and 13 inches) than did frilling. Essentially all mortality occurred within the first 15 months following treatment.

  13. Antioxidant ability of fractionated apple peel phenolics to inhibit fish oil oxidation.

    PubMed

    Sekhon-Loodu, Satvir; Warnakulasuriya, Sumudu N; Rupasinghe, H P Vasantha; Shahidi, Fereidoon

    2013-09-01

    Polyphenols isolated from frozen and dried apple peels were studied as potential natural antioxidants to stabilize omega-3 polyunsaturated fatty acid (ω3 PUFA) enriched fish oil. The ethanolic extracts of apple peels were fractionated by reversed phase chromatography using gradient elution of 20-100% aqueous ethanol. The collected fractions were analyzed by ultra pressure liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS). The total phenolic content and antioxidant capacity of each fraction were evaluated by Folin-Ciocalteu (FC), ferric reducing antioxidant power (FRAP) and 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging assays. Inhibition of fish oil oxidation was studied using the thiobarbituric acid reactive substances (TBARS) assay. Polyphenols fractionated using frozen apple peel extract had significantly higher FC, FRAP and DPPH(·) scavenging values than those of dried apple peel (p<0.05). The flavonol-rich fractions inhibited fish oil oxidation by 40-62% at a total phenolic concentration of 200 μg/ml. The fractionated polyphenols from both dried and frozen apple peel showed higher inhibition of lipid oxidation compared to α-tocopherol, butylated hydroxytoluene and crude apple peel extracts. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. [Comparative study of chemical composition of pomegranate peel pomegranates inside and pomegranate seeds].

    PubMed

    Zhou, Qian; Sun, Li-Li; Dai, Yan-Peng; Wang, Liang; Su, Ben-Zheng

    2013-07-01

    An HPLC fingerprint of pomegranate peel was established. Using chromatographic conditions, we compared the chemical composition of pomegranate peel, inside and seeds, and simultaneously determined the contents of gallic acid and ellagic acid. By comparison, we found that there were no significant differences between pomegranate peel and inside, but there was a big difference between pomegranate seeds and another two. The contents of gallic acid and ellagic acid of pomegranate peel respectively were 0.33%, 0.59%, while in pomegranate inside the result respectively were 0.52%, 0.38%. Content of ellagic acid from pomegranate seeds was only 0.01%. By study, we thought that when pomegranate peel was processed, pomegranate seeds should be removed, while pomegranate inside could be retained on the premise of full drying.

  15. Bringing diagnostics to developing countries: an interview with Rosanna Peeling.

    PubMed

    Peeling, Rosanna

    2015-01-01

    Interview with Professor Rosanna Peeling, PhD by Claire Raison (Commissioning Editor) Professor Rosanna Peeling is Chair of Diagnostic Research at the London School of Hygiene and Tropical Medicine (London, UK) and founded the International Diagnostics Centre at the institution. Professor Peeling previously worked for the WHO in Geneva, Switzerland, and continues to work on innovations for molecular diagnostics for point-of-care use in developing countries, addressing challenges posed by lack of funding and resources, regulatory issues and under-developed healthcare systems in these locations. Here, she discusses her career, recent progress in the field and how connectivity will affect global healthcare.

  16. Studies on the development of functional powder from citrus peel.

    PubMed

    Kang, H J; Chawla, S P; Jo, C; Kwon, J H; Byun, M W

    2006-03-01

    The suitability of citrus peels, generated as a by-product of the juice industry, as a source of antioxidants was investigated. Citrus peel powder was prepared by lyophilizing 70% ethanol extract from citrus peels. Extraction was carried out at room temperature (20 degrees C) for 72 h. The extract was subjected to gamma-irradiation treatment (20 kGy). The aqueous solutions of citrus peel powder were examined for color characteristics and antioxidant potential in terms of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, beta-carotene bleaching and nitrite scavenging activities. There were significant changes in Hunter color values due to irradiation. The a*- and b*-values decreased due to radiation treatment. DPPH radical scavenging, beta-carotene bleaching and nitrite scavenging activities were not affected by irradiation treatment. Nitrite scavenging activity was the highest in the extract at pH 1.2 followed by pH 4.2 and 6.0. These functional properties of the aqueous solution were found to be stable in heat treatment. It could significantly improve oxidative stability of lipids in fish meat system. Based on these results there may be opportunities to use citrus peel powder as a functional component in the food processing industry with gamma irradiation treatment improving its color characteristics without adversely influencing the functional properties.

  17. Preventive effect of chemical peeling on ultraviolet induced skin tumor formation.

    PubMed

    Abdel-Daim, Mohamed; Funasaka, Yoko; Kamo, Tsuneyoshi; Ooe, Masahiko; Matsunaka, Hiroshi; Yanagita, Emmy; Itoh, Tomoo; Nishigori, Chikako

    2010-10-01

    Chemical peeling is one of the dermatological treatments available for certain cutaneous diseases and conditions or improvement of cosmetic appearance of photoaged skin. We assessed the photochemopreventive effect of several clinically used chemical peeling agents on the ultraviolet (UV)-irradiated skin of hairless mice. Chemical peeling was done using 35% glycolic acid dissolved in distilled water, 30% salicylic acid in ethanol, 10% or 35% trichloroacetic acid (TCA) in distilled water at the right back of UV-irradiated hairless mice every 2 weeks in case of glycolic acid, salicylic acid, and 10% TCA and every 4 weeks in case of 35% TCA for totally 18 weeks after the establishment of photoaged mice by irradiation with UVA+B range light three times a week for 10 weeks at a total dose of 420 J/cm(2) at UVA and 9.6 J/cm(2) at UVB. Tumor formation was assessed every week. Skin specimens were taken from treated and non-treated area for evaluation under microscopy, evaluation of P53 expression, and mRNA expression of cyclooxygenase (COX)-2. Serum level of prostaglandin E(2) was also evaluated. All types of chemical peeling reduced tumor formation in treated mice, mostly in the treated area but also non-treated area. Peeling suppressed clonal retention of p53 positive abnormal cells and reduced mRNA expression of COX-2 in treated skin. Further, serum prostaglandin E(2) level was decreased in chemical peeling treated mice. These results indicate that chemical peeling with glycolic acid, salicylic acid, and TCA could serve tumor prevention by removing photodamaged cells. Copyright © 2010 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.

  18. An HPLC-MS analysis of phenolic antioxidants in banana peel

    USDA-ARS?s Scientific Manuscript database

    Banana peels are rich in many nutrients which allow for their use as food ingredients and biofertilizers in tropical agriculture. The phenomenon of rapid peel browning is a common occurrence, and is attributable to the peel’s high polyphenol oxidase activity and high concentrations of polyphenols. ...

  19. New early instrumental series since the beginning of the 19th century in eastern Iberia (Valencia, Spain)

    NASA Astrophysics Data System (ADS)

    Sanchez-Lorenzo, Arturo; Barriendos, Mariano; Guinaldo, Elena; Lopez-Bustins, Joan A.

    2010-05-01

    Early instrumental series are the main source for climate information in the 18th and the first part of the 19th century, which is when systematic meteorological observations started in most national meteorological services. The first continuous series in Spain starts in 1780 in Barcelona due to meteorological observations made by the medical doctor Francisco Salvá Campillo. Moreover, only two other series have been recovered at the present in Spain: Madrid and Cádiz/San Fernando. Until present, in Spain the major part of the meteorological observations detected in early instrumental periods were made by medical doctors, who started to pay attention to the environmental factors influencing population health under the Hippocrates oath, although also there are military institutions and academic university staff (e.g. physicists, mathematicians, etc.). Due to the high spatial and temporal climate variability in the Iberian Peninsula, it is important to recover and digitize more climatic series, and this is one of the main goals of the Salvá-Sinobas project (http://salva-sinobas.uvigo.es/) funded by the Spanish Ministry of Environment, and Rural and Marine Affairs for the 2009-2011 period. The first new series with systematic observations was detected in the city of Valencia, in the eastern façade of the Iberian Peninsula. The meteorological observations were daily published in the newspapers Diario de Valencia (1804-1834) and Diario Mercantil de Valencia (1837-1863) until official meteorological observations started in 1858 at the University of Valencia. Each day 3-daily observations (morning, midday, afternoon) were published with five climatic variables: temperature, air pressure, humidity, wind direction and the sky state. Only during the 1804-1808 period daily rainfall data is available. We checked the observer comments published in the newspapers to obtain metadata about the instruments and meteorological station information. Unfortunately, temperature data

  20. Effect of bending stiffness on the peeling behavior of an elastic thin film on a rigid substrate.

    PubMed

    Peng, Zhilong; Chen, Shaohua

    2015-04-01

    Inspired by the experimental observation that the maximum peeling force of elastic films on rigid substrates does not always emerge at the steady-state peeling stage, but sometimes at the initial one, a theoretical model is established in this paper, in which not only the effect of the film's bending stiffness on the peeling force is considered, but also the whole peeling process, from the initiation of debonding to the steady-state stage, is characterized. Typical peeling force-displacement curves and deformed profiles of the film reappear for the whole peeling process. For the case of a film with relatively large bending stiffness, the maximum peeling force is found arising at the initial peeling stage and the larger the stiffness of the film, the larger the maximum peeling force is. With the peeling distance increasing, the peeling force is reduced from the maximum to a constant at the steady-state stage. For the case of a film with relatively small stiffness, the peeling force increases monotonically at the initial stage and then achieves a constant as the maximum at the steady-state stage. Furthermore, the peeling forces in the steady-state stage are compared with those of the classical Kendall model. All the theoretical predictions agree well with the existing experimental and numerical observations, from which the maximum peeling force can be predicted precisely no matter what the stiffness of the film is. The results in this paper should be very helpful in the design and assessment of the film-substrate interface.

  1. Peel/seal properties of poly(ethylene methyl acrylate)/polybutene-1 blend films

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mohammdi, Seyedeh Raziyeh; Ajji, Abdellah; Tabatabaei, Seyed H.

    Nowadays, the possibility to easy open a food package is of great interest both from the consumer and food producers’ perspective. In this study, the peel/seal properties of poly (ethylene methyl acrylate) (EMA)/polybutene-1 (PB-1) blend films were investigated. Three blends of EMA/PB-1 with different methyl acrylate (MA) content were prepared using cast extrusion process. Differential Scanning Calorimetry (DSC) was used to investigate the thermal behavior as well as the crystalinity of the blends. The effect of polymer matrix on the crystalline structure of PB-1 was studied using Wide Angle X-ray Diffraction (WAXD) and DSC. T-peel tests were carried out onmore » the heat sealed films at various seal temperatures. The effect of MA content and heat seal temperature on peel/seal properties (i.e. peel initiation temperature, temperature window of sealability and peel strength) of the films were studied.« less

  2. Salicylic acid peels for the treatment of acne vulgaris in Asian patients.

    PubMed

    Lee, Ho-Sup; Kim, Il-Hwan

    2003-12-01

    Salicylic acid peels have been introduced as a useful modality in acne treatment. Few studies have examined its efficacy and safety, especially in darker skin. To assess the efficacy and safety of salicylic acid peels as a treatment for acne vulgaris in Asian patients. Thirty-five Korean patients with facial acne were treated with 30% salicylic acid peels biweekly for 12 weeks. Lesion counts and Dr. Cunliffe's score were assessed by a blinded evaluator. Safety assessments and patient's evaluations were also recorded. Both inflammatory and noninflammatory acne lesion counts were decreased in proportion to the duration of treatment. Dr. Cunliffe's acne grade was statistically significantly decreased after treatment. The side effects were tolerable in most cases, and all patients were pleased with their peel results. Stratum corneum hydration, skin surface lipid, skin pH, and transepidermal water loss were unchanged from baseline levels. Salicylic acid peels are an effective and safe therapy for acne vulgaris in Asian patients.

  3. Synergistic Use of SMOS Measurements with SMAP Derived and In-situ Data over Valencia Anchor Station by Using Downscaling Technique

    NASA Astrophysics Data System (ADS)

    Ansari Amoli, Abdolreza; Lopez-Baeza, Ernesto; Mahmoudi, Ali; Mahmoodi, Ali

    2016-07-01

    Synergistic Use of SMOS Measurements with SMAP Derived and In-situ Data over the Valencia Anchor Station by Using a Downscaling Technique Ansari Amoli, A.(1),Mahmoodi, A.(2) and Lopez-Baeza, E.(3) (1) Department of Earth Physics and Thermodynamics, University of Valencia, Spain (2) Centre d'Etudes Spatiales de la BIOsphère (CESBIO), France (3) Department of Earth Physics and Thermodynamics, University of Valencia, Spain Soil moisture products from active sensors are not operationally available. Passive remote sensors return more accurate estimates, but their resolution is much coarser. One solution to overcome this problem is the synergy between radar and radiometric data by using disaggregation (downscaling) techniques. Few studies have been conducted to merge high resolution radar and coarse resolution radiometer measurements in order to obtain an intermediate resolution product. In this paper we present an algorithm using combined available SMAP (Soil Moisture Active and Passive) radar and SMOS (Soil Moisture and Ocean Salinity) radiometer measurements to estimate surface soil moisture over the Valencia Anchor Station (VAS), Valencia, Spain. The goal is to combine the respective attributes of the radar and radiometer observations to estimate soil moisture at a resolution of 3 km. The algorithm disaggregates the coarse resolution SMOS (15 km) radiometer brightness temperature product based on the spatial variation of the high resolution SMAP (3 km) radar backscatter. The disaggregation of the radiometer brightness temperature uses the radar backscatter spatial patterns within the radiometer footprint that are inferred from the radar measurements. For this reason the radar measurements within the radiometer footprint are scaled by parameters that are derived from the temporal fluctuations in the radar and radiometer measurements.

  4. Theoretical and Experimental Evaluation of the Bond Strength Under Peeling Loads

    NASA Technical Reports Server (NTRS)

    Nayeb-Hashemi, Hamid; Jawad, Oussama Cherkaoui

    1997-01-01

    Reliable applications of adhesively bonded joints require understanding of the stress distribution along the bond-line and the stresses that are responsible for the joint failure. To properly evaluate factors affecting peel strength, effects of defects such as voids on the stress distribution in the overlap region must be understood. In this work, the peel stress distribution in a single lap joint is derived using a strength of materials approach. The bonded joint is modeled as Euler-Bernoulli beams, bonded together with an adhesive. which is modeled as an elastic foundation which can resist both peel and shear stresses. It is found that for certain adhesive and adherend geometries and properties, a central void with the size up to 50 percent of the overlap length has negligible effect on the peak peel and shear stresses. To verify the solutions obtained from the model, the problem is solved again by using the finite element method and by treating the adherends and the adhesive as elastic materials. It is found that the model used in the analysis not only predicts the correct trend for the peel stress distribution but also gives rather surprisingly close results to that of the finite element analysis. It is also found that both shear and peel stresses can be responsible for the joint performance and when a void is introduced, both of these stresses can contribute to the joint failure as the void size increases. Acoustic emission (AE) activities of aluminum-adhesive-aluminum specimens with different void sizes were monitored. The AE ringdown counts and energy were very sensitive and decreased significantly with the void size. It was observed that the AE events were shifting towards the edge of the overlap where the maximum peeling and shearing stresses were occurring as the void size increased.

  5. Rate-dependent elastic hysteresis during the peeling of pressure sensitive adhesives.

    PubMed

    Villey, Richard; Creton, Costantino; Cortet, Pierre-Philippe; Dalbe, Marie-Julie; Jet, Thomas; Saintyves, Baudouin; Santucci, Stéphane; Vanel, Loïc; Yarusso, David J; Ciccotti, Matteo

    2015-05-07

    The modelling of the adherence energy during peeling of Pressure Sensitive Adhesives (PSA) has received much attention since the 1950's, uncovering several factors that aim at explaining their high adherence on most substrates, such as the softness and strong viscoelastic behaviour of the adhesive, the low thickness of the adhesive layer and its confinement by a rigid backing. The more recent investigation of adhesives by probe-tack methods also revealed the importance of cavitation and stringing mechanisms during debonding, underlining the influence of large deformations and of the related non-linear response of the material, which also intervenes during peeling. Although a global modelling of the complex coupling of all these ingredients remains a formidable issue, we report here some key experiments and modelling arguments that should constitute an important step forward. We first measure a non-trivial dependence of the adherence energy on the loading geometry, namely through the influence of the peeling angle, which is found to be separable from the peeling velocity dependence. This is the first time to our knowledge that such adherence energy dependence on the peeling angle is systematically investigated and unambiguously demonstrated. Secondly, we reveal an independent strong influence of the large strain rheology of the adhesives on the adherence energy. We complete both measurements with a microscopic investigation of the debonding region. We discuss existing modellings in light of these measurements and of recent soft material mechanics arguments, to show that the adherence energy during peeling of PSA should not be associated to the propagation of an interfacial stress singularity. The relevant deformation mechanisms are actually located over the whole adhesive thickness, and the adherence energy during peeling of PSA should rather be associated to the energy loss by viscous friction and by rate-dependent elastic hysteresis.

  6. Efficacy of peeling during different periods of the menstrual cycle on acne.

    PubMed

    Bulbul Baskan, Emel; Tilki Günay, Işıl; Saricaoglu, Hayriye

    2017-10-01

    The aim of this study was to investigate the efficacy of 50% glycolic acid peeling performed at different phases of menstruation on acne. This study included 30 patients with mild-to-moderate acne. Those with regular menstrual cycles and no history or laboratory evidence of hormonal pathology, hirsutism were selected. Thirty patients were divided in three groups. The first group received peeling applications in the first 7 days of menstruation; the second group received the peel between 10 and 14 days; and the third group received the peel during the last 10 days of menstruation. The 30 female patients included in study. All patients' menstrual cycles were regular. All groups were homogenous in terms of initial acne severity scores. Acne severity scores decreased in all groups after 3 months of therapy; statistically significant differences were achieved only in the second group. The results of our study suggest that chemical peeling administered during ovulation provides the most significant benefit for acne lesions. Ovulation is the period when estrogen reaches its highest level. Estrogen decreases sebum production through different mechanisms. The beneficial effects of estrogen on acne and healing in combination with those of chemical peeling may cause synergistic therapeutic effects with pronounced results.

  7. Can using a peel-away sheath in shunt implantation prevent ventricular catheter obstruction?

    PubMed

    Camlar, Mahmut; Ersahin, Yusuf; Ozer, Fusun Demirçivi; Sen, Fatih; Orman, Mehmet

    2011-02-01

    Shunt obstruction is the most common shunt complication. In 2003, Kehler et al. used peel-away sheath while implanting the ventricular catheter in 20 patients. They found less revision rate in the peel-away sheath group. We aimed to test the efficacy of this technique in cadavers. We used 100 fresh brains obtained from medicolegal autopsies. Posterior parietal and frontal approaches were used to puncture the lateral ventricle in each cerebral hemisphere. The ventricle is punctured with a peel-away sheath system. After the ventricle is reached, the mandarin is retracted and the ventricular catheter is introduced through the opening. The ventricular catheter was removed from the ventricle, the opening at the tip of the ventricular catheter was checked out for obstruction, and the number of patent and plugged openings was recorded. This procedure was repeated four times for each location with and without using peel-away sheath. The control group consisted of the procedures done without using peel-away sheath. The number of the plugged openings in the peel-away sheath group was significantly smaller than the control group. There was no significant difference between the two groups in terms of gender and left and right cerebral hemispheres. The obstruction rate was significantly lower in the posterior parietal approach. Pearson's correlation showed that increasing age was associated with less obstruction rate. Peel-away sheath decreases the number of plugged openings of the ventricular catheter. A clinical cooperative study is needed to prove that a peel-away sheath should be included in the ventricular shunt systems in the market.

  8. Feasibility of Jujube peeling using novel infrared radiation heating technology

    USDA-ARS?s Scientific Manuscript database

    Infrared (IR) radiation heating has a promising potential to be used as a sustainable and effective method to eliminate the use of water and chemicals in the jujube-peeling process and enhance the quality of peeled products. The objective of this study was to investigate the feasibility of use IR he...

  9. The efficacy of various degreasing agents used in trichloroacetic acid peels.

    PubMed

    Peikert, J M; Krywonis, N A; Rest, E B; Zachary, C B

    1994-11-01

    Adequate preparation of the skin is necessary for a successful chemical peel. Little detailed attention has been given to the effect of degreasing on the efficacy of the peel. To assess the influence of degreasers on the peel, compare their flammabilities, and discuss alternatives. Six patients with androgenetic alopecia and widespread actinic keratoses of the scalp were treated with 35% trichloroacetic acid. Scalps were divided into sections and degreased with acetone, rubbing alcohol, Freon Skin Degreaser, or Hibiclens. The influence of these degreasers on trichloroacetic acid peels was assessed by clinical and histologic examination. Acetone was not found to be superior to the other agents. Furthermore, the flashpoint of acetone is markedly lower than the others, making it more flammable and hazardous in the workplace. The use of alternative degreasers may lessen or eliminate this hazard.

  10. Development of eco-friendly process for the production of bioethanol from banana peel using inhouse developed cocktail of thermo-alkali-stable depolymerizing enzymes.

    PubMed

    Prakash, Heena; Chauhan, Prakram Singh; General, Thiyam; Sharma, A K

    2018-07-01

    Conversion of agro-industrial wastes to energy is an innovative approach for waste valorization and management which also mitigates environmental pollution. In this view, present study investigated the feasibility of producing bioethanol from banana peels using cocktail of depolymerizing enzyme/s. We isolated Geobacillus stearothermophilus HPA19 from natural resource which produces cocktail of thermo-alkali-stable xylano-pectino-cellulolytic enzyme/s using wheat bran within 24 h. The optimal temperature and pH for xylanase, filter paper cellulase and pectinase were 80, 70 and 80 °C, and 9.0, 8.0 and 9.0, respectively. Cocktail enzymes showed stability at high temperature (80 °C) and pH (10.0). Ni 2+ and Zn 2+ promoted the relative activity of xylanase and FPase, whereas Na + , Ca 2+ and K + promoted pectinase activity. Cocktail was assessed in saccharification of banana peel. Reducing sugar obtained (37.06 mg ml -1 ) after one variable at a time (OVAT) method is greatly influenced by enzyme dose. Further, response surface methodology was used to optimize saccharification leading to twofold increase in reducing sugar. Maximum ethanol production (21.1 gl -1 ) was achieved through fermentation giving the efficiency of 76.5% within 30 h. Hence utilization of waste biomass for production of value-added products through biotechnological intervention not only helps to combat environmental pollution but also contributes significantly to the economy.

  11. Salicylic acid peeling combined with vitamin C mesotherapy versus salicylic acid peeling alone in the treatment of mixed type melasma: A comparative study.

    PubMed

    Balevi, Ali; Ustuner, Pelin; Özdemir, Mustafa

    2017-10-01

    Melasma is a distressing condition for both dermatologists and patients. We evaluated the effectiveness of salicylic acid (SA) peel and vitamin C mesotherapy in the treatment of melasma. Fifty female patients were divided into two groups. All patients were treated with 30% SA peel every two weeks for two months. In addition, after SA peeling Group A was intradermally administered 10 vitamin C on the melasma lesion at 1-cm intervals. All patients were followed up for 6 months, during which the recurrence rates were evaluated. Digital photographs of the melasma site were taken and patients' Melasma Area and Severity Index (MASI) scores were assessed. After the treatment, the patients were asked to complete the melasma quality of life questionnaire (MelasQoL) to evaluate their satisfaction with the treatment. All the adverse effects were noted. The MelasQoL and MASI scores of patients in both groups significantly decreased after the treatment. Apart from a burning sensation, no adverse event was observed and all patients tolerated the treatment well. SA peel combined with vitamin C mesotherapy is a safe and effective alternative for the treatment of melasma with no significant side effects and minimal downtime.

  12. Bioactive Flavonoids, Antioxidant Behaviour, and Cytoprotective Effects of Dried Grapefruit Peels (Citrus paradisi Macf.)

    PubMed Central

    Castro-Vazquez, Lucia; Alañón, María Elena; Rodríguez-Robledo, Virginia; Pérez-Coello, María Soledad; Hermosín-Gutierrez, Isidro; Díaz-Maroto, María Consuelo; Jordán, Joaquín; Galindo, María Francisca; Arroyo-Jiménez, María del Mar

    2016-01-01

    Grapefruit (Citrus paradisi Macf.) is an important cultivar of the Citrus genus which contains a number of nutrients beneficial to human health. The objective of the present study was to evaluate changes in bioactive flavonoids, antioxidant behaviour, and in vitro cytoprotective effect of processed white and pink peels after oven-drying (45°C–60°C) and freeze-drying treatments. Comparison with fresh grapefruit peels was also assessed. Significant increases in DPPH, FRAPS, and ABTS values were observed in dried grapefruit peel samples in comparison with fresh peels, indicating the suitability of the treatments for use as tools to greatly enhance the antioxidant potential of these natural byproducts. A total of thirteen flavonoids were quantified in grapefruit peel extracts by HPLC-MS/MS. It was found that naringin, followed by isonaringin, was the main flavonoid occurring in fresh, oven-dried, and freeze-dried grapefruit peels. In vivo assay revealed that fresh and oven-dried grapefruit peel extracts (45°C) exerted a strong cytoprotective effect on SH-SY5Y neuroblastoma cell lines at concentrations ranging within 0.1–0.25 mg/mL. Our data suggest that grapefruit (Citrus paradisi Macf.) peel has considerable potential as a source of natural bioactive flavonoids with outstanding antioxidant activity which can be used as agents in several therapeutic strategies. PMID:26904169

  13. A study of the effects of physical dermabrasion combined with chemical peeling in porcine skin.

    PubMed

    Kang, Boo Kyoung; Choi, Jeong Hwee; Jeong, Ki Heon; Park, Jong Min; Suh, Dong Hye; Lee, Sang Jun; Shin, Min Kyung

    2015-02-01

    Many comparative studies of chemical peeling and dermabrasion have been reported. However, rare basic scientific data about the immediate effects after combined treatment with chemical peeling and dermabrasion have been confirmed. The aim of this study is to evaluate the effect of the application of physical abrasion in combination with chemical peels. Three pigs were treated with physical abrasion using a water jet device in combination with an α-hydroxy acid solution, and the skin samples of the control received chemical peeling solution alone. The levels of growth factors and neuropeptides were measured with a multiplex immunoassay. Skin treated with physical dermabrasion combined with chemical peeling showed prominent detachment and swelling of the stratum corneum (SC), and fluid collection in the hair follicles. The mean cell count of CD34 positive fibroblasts and mast cells, levels of epidermal growth factor, fibroblast growth factor-2, vascular endothelial growth factor, and neurotensin, were significantly increased in the tissue treated with physical abrasion combined with a chemical peeling agent, compared to the skin in the control. We concluded that physical dermabrasion combined with chemical peeling can be more effective than chemical peeling alone, for the approach through transfollicular routes.

  14. Numerical implementation of multiple peeling theory and its application to spider web anchorages.

    PubMed

    Brely, Lucas; Bosia, Federico; Pugno, Nicola M

    2015-02-06

    Adhesion of spider web anchorages has been studied in recent years, including the specific functionalities achieved through different architectures. To better understand the delamination mechanisms of these and other biological or artificial fibrillar adhesives, and how their adhesion can be optimized, we develop a novel numerical model to simulate the multiple peeling of structures with arbitrary branching and adhesion angles, including complex architectures. The numerical model is based on a recently developed multiple peeling theory, which extends the energy-based single peeling theory of Kendall, and can be applied to arbitrarily complex structures. In particular, we numerically show that a multiple peeling problem can be treated as the superposition of single peeling configurations even for complex structures. Finally, we apply the developed numerical approach to study spider web anchorages, showing how their function is achieved through optimal geometrical configurations.

  15. Numerical implementation of multiple peeling theory and its application to spider web anchorages

    PubMed Central

    Brely, Lucas; Bosia, Federico; Pugno, Nicola M.

    2015-01-01

    Adhesion of spider web anchorages has been studied in recent years, including the specific functionalities achieved through different architectures. To better understand the delamination mechanisms of these and other biological or artificial fibrillar adhesives, and how their adhesion can be optimized, we develop a novel numerical model to simulate the multiple peeling of structures with arbitrary branching and adhesion angles, including complex architectures. The numerical model is based on a recently developed multiple peeling theory, which extends the energy-based single peeling theory of Kendall, and can be applied to arbitrarily complex structures. In particular, we numerically show that a multiple peeling problem can be treated as the superposition of single peeling configurations even for complex structures. Finally, we apply the developed numerical approach to study spider web anchorages, showing how their function is achieved through optimal geometrical configurations. PMID:25657835

  16. Vitrectomy with or without internal limiting membrane peeling for idiopathic epiretinal membrane: A meta-analysis.

    PubMed

    Chang, Wei-Cheng; Lin, Chin; Lee, Cho-Hao; Sung, Tzu-Ling; Tung, Tao-Hsin; Liu, Jorn-Hon

    2017-01-01

    Studies on vitrectomy with and without internal limiting membrane (ILM) peeling for idiopathic epiretinal membrane (ERM) have yielded uncertain results regarding clinical outcomes and recurrence rates. To compare the clinical outcomes of vitrectomy with and without ILM peeling for idiopathic ERM. Databases, including PubMed, Embase, Cochrane, Web of Science, Google Scholar, CNKI databases, FDA.gov, and ClinicalTrials.gov, published until July 2016, were searched to identify studies comparing the clinical outcomes following vitrectomy with ERM and ILM peeling and with only ERM peeling, for treating idiopathic ERM. Studies with sufficient data were selected. Pooled results were expressed as mean differences (MDs) and risk ratios (RRs) with corresponding 95% confidence intervals (CI) for vitrectomy with and without ILM peeling with regard to postoperative best corrected visual acuity (BCVA), central retinal thickness (CRT), and ERM recurrence rate. Eleven retrospective studies and one randomized controlled trial involving 756 eyes were identified. This demonstrated that the postoperative BCVA within 12 months was significantly better in the non-ILM peeling group (MD = 0.04, 95% CI: 0.00 to 0.08; P = 0.0460), but that the patients in the ILM peeling group had significantly better postoperative BCVA after 18 months (MD = -0.13, 95% CI: -0.23 to -0.04; P = 0.0049) than did those in the non-ILM peeling group. The non-ILM peeling group exhibited a higher reduction in postoperative CRT (MD = 51.55, 95% CI:-84.23 to -18.88; P = 0.0020) and a higher recurrence rate of ERM (RR = 0.34, 95% CI:0.16 to 0.72; P = 0.0048) than did the ILM peeling group. However, the improvement rates of BCVA (RR = 1.03, 95% CI:0.72 to 1.47; P = 0.8802) and postoperative CRTs (MD = 18.15, 95% CI:-2.29 to 38.60; P = 0.0818) were similar between the two groups. Vitrectomy with ILM peeling results in better visual improvement in long-term follow-ups and lower ERM recurrence rates, and vitrectomy with

  17. Vitrectomy with or without internal limiting membrane peeling for idiopathic epiretinal membrane: A meta-analysis

    PubMed Central

    Lin, Chin; Lee, Cho-Hao; Sung, Tzu-Ling; Tung, Tao-Hsin

    2017-01-01

    Background Studies on vitrectomy with and without internal limiting membrane (ILM) peeling for idiopathic epiretinal membrane (ERM) have yielded uncertain results regarding clinical outcomes and recurrence rates. Objective To compare the clinical outcomes of vitrectomy with and without ILM peeling for idiopathic ERM. Methods Databases, including PubMed, Embase, Cochrane, Web of Science, Google Scholar, CNKI databases, FDA.gov, and ClinicalTrials.gov, published until July 2016, were searched to identify studies comparing the clinical outcomes following vitrectomy with ERM and ILM peeling and with only ERM peeling, for treating idiopathic ERM. Studies with sufficient data were selected. Pooled results were expressed as mean differences (MDs) and risk ratios (RRs) with corresponding 95% confidence intervals (CI) for vitrectomy with and without ILM peeling with regard to postoperative best corrected visual acuity (BCVA), central retinal thickness (CRT), and ERM recurrence rate. Results Eleven retrospective studies and one randomized controlled trial involving 756 eyes were identified. This demonstrated that the postoperative BCVA within 12 months was significantly better in the non-ILM peeling group (MD = 0.04, 95% CI: 0.00 to 0.08; P = 0.0460), but that the patients in the ILM peeling group had significantly better postoperative BCVA after 18 months (MD = −0.13, 95% CI: −0.23 to −0.04; P = 0.0049) than did those in the non-ILM peeling group. The non-ILM peeling group exhibited a higher reduction in postoperative CRT (MD = 51.55, 95% CI:−84.23 to −18.88; P = 0.0020) and a higher recurrence rate of ERM (RR = 0.34, 95% CI:0.16 to 0.72; P = 0.0048) than did the ILM peeling group. However, the improvement rates of BCVA (RR = 1.03, 95% CI:0.72 to 1.47; P = 0.8802) and postoperative CRTs (MD = 18.15, 95% CI:−2.29 to 38.60; P = 0.0818) were similar between the two groups. Conclusions Vitrectomy with ILM peeling results in better visual improvement in long

  18. [Prevalence of exposure to occupational risks in pregnant Spanish workers (the INMA Project-Valencia)].

    PubMed

    González-Galarzo, M Carmen; García, Ana M; Estarlich, Marisa; García García, Francisco; Esplugues, Ana; Rodríguez, Paz; Rebagliato, Marisa; Ballester, Ferran

    2009-01-01

    To describe the prevalence of exposure to occupational risks among pregnant women and analyze its relationship with personal and occupational characteristics using information collected in the Childhood and Environment (Infancia y Medio Ambiente [INMA])-Valencia cohort study. The INMA-Valencia cohort study started in 2004 with 855 pregnant women living in Valencia, Spain. Data on sociodemographic variables (age, education and country of birth) and occupational conditions (activity, occupation, type of contract, working hours and self-reported occupational exposure to physical load and psychosocial, physical, chemical and biological risks) in women with paid employment during pregnancy (n=649) were collected through face-to-face interviews with a structured questionnaire in week 32 of pregnancy. The prevalences of reported exposure to physical and psychosocial load and to physical pollutants (including non-ionizing radiations) were 56%, 63% and 62%, respectively. The prevalence of reported exposure to chemicals (including cleaning products) and biological pollutants was 22% and 6%, respectively. In general, the characteristics most closely associated with exposure to occupational risks were younger age, non-Spanish nationality, lower education, having a temporary contract or being self-employed. This study is the first to quantify the prevalence of exposure to occupational risks during pregnancy in a Spanish population-based sample. According to the data observed, surveillance and control actions should be intensified in pregnant workers, as some of the observed occupational exposures have been consistently associated with detrimental reproductive and developmental effects.

  19. Isolation and characterization of cellulose nanofibers from culinary banana peel using high-intensity ultrasonication combined with chemical treatment.

    PubMed

    Khawas, Prerna; Deka, Sankar C

    2016-02-10

    In the present study, culinary banana peel was explored as a source of raw material for production of cellulose nanofibers (CNFs). For isolation of CNFs, first the peel flour was subjected to different chemical treatments to eliminate non-cellulosic compounds. The obtained chemically treated cellulose fibers were then mechanically tailored and separated into nanofibers using high-intensity ultrasonication at different output power ranging from 0 to 1000 W. The presences of nanofibers in all samples were confirmed by TEM. Increasing output power of ultrasonication reduced size of CNFs and generated more thinner and needle-like structure. SEM, FT-IR and XRD results indicated chemical treatment employed was effective in removing compounds other than cellulose fibers. Thermal analyses evinced the developed CNFs enhanced thermal properties which serve the purpose as an effective reinforcing material to be used as bionanocomposites. Hence, the production of CNFs from this underutilized agro-waste has potential application in commercial field that can add high value to culinary banana. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Carbon-Based Fe₃O₄ Nanocomposites Derived from Waste Pomelo Peels for Magnetic Solid-Phase Extraction of 11 Triazole Fungicides in Fruit Samples.

    PubMed

    Ren, Keyu; Zhang, Wenlin; Cao, Shurui; Wang, Guomin; Zhou, Zhiqin

    2018-05-06

    Carbon-based Fe₃O₄ nanocomposites (C/Fe₃O₄ NCs) were synthesized by a simple one-step hydrothermal method using waste pomelo peels as the carbon precursors. The characterization results showed that they had good structures and physicochemical properties. The prepared C/Fe₃O₄ NCs could be applied as excellent and recyclable adsorbents for magnetic solid phase extraction (MSPE) of 11 triazole fungicides in fruit samples. In the MSPE procedure, several parameters including the amount of adsorbents, extraction time, the type and volume of desorption solvent, and desorption time were optimized in detail. Under the optimized conditions, the good linearity ( R ² > 0.9916), the limits of detection (LOD), and quantification (LOQ) were obtained in the range of 1⁻100, 0.12⁻0.55, and 0.39⁻1.85 μg/kg for 11 pesticides, respectively. Lastly, the proposed MSPE method was successfully applied to analyze triazole fungicides in real apple, pear, orange, peach, and banana samples with recoveries in the range of 82.1% to 109.9% and relative standard deviations (RSDs) below 8.4%. Therefore, the C/Fe₃O₄ NCs based MSPE method has a great potential for isolating and pre-concentrating trace levels of triazole fungicides in fruits.

  1. Hydrochar production from watermelon peel by hydrothermal carbonization.

    PubMed

    Chen, Xuejiao; Lin, Qimei; He, Ruidong; Zhao, Xiaorong; Li, Guitong

    2017-10-01

    Watermelon peel waste was hydrothermally carbonized under 190°C and 260°C for 1h, 6h, and 12h, respectively. The hydrochar and spent liquor were collected and assayed for their properties. The results indicated that hydrochar yield was 2-5% and 46-95% on fresh and dry matter, respectively. Low temperature (190°C) was conducive to high conversion efficiency. The hydrochar had higher C/N ratio (22.19-26.86), more alkyl C, aryl C, and carbonyl C, but lower H/C (0.98-1.22) and O/C ratios (0.13-0.38), and less O-alky C, carboxylic C, compared with feedstock. So the aliphaticity decreased, whereas aromaticity increased significantly, especially under severe conditions. It should be watchful for that the toxic compounds in hydrochar may induce environmental risk while it is amended into soil. The spent liquor with abundant nutrients could be used as a fertilizer. Further work is required for testing the application in soil. Copyright © 2017. Published by Elsevier Ltd.

  2. Numerical models of delamination behavior in 2G HTS tapes under transverse tension and peel

    NASA Astrophysics Data System (ADS)

    Duan, Yujie; Ta, Wurui; Gao, Yuanwen

    2018-02-01

    In extreme operating environments, delamination in 2G HTS tapes occurs within and/or near the superconductor layer from high transverse tensile stresses caused by fabrication, Lorentz forces and thermal mismatch, etc. Generally, transverse opening and peeling off are the main delamination modes, and are always studied in anvil and peel tests, respectively. Numerical models of these modes for 2G HTS tape are presented wherein the mixed-mode traction-separation law at the interface of the silver and superconductor layers is considered. Plastic deformations of copper, silver, and Hastelloy® in the HTS tape are taken into account. The results obtained from the transverse opening model show that the maximum average tensile stress is smaller than the delamination tensile strength because delamination is asynchronous in the tape. When a crack appears in the tape, only a small stress ( ≤ 1 MPa) is required to expand the crack to other stress free areas through peeling. Using the peeling model, the dependency of the peel strength on peeling angle is investigated under constant fracture toughness. Peel strength decreases with the peeling angle until the minimum value is reached at 150°, and thereafter increases slightly. Other results indicate that peel strength depends strongly on delamination strength, fracture toughness, and thickness of copper layer. The fracture toughness of the delamination interface, which is difficult to obtain by experiment, can be extracted using the present model.

  3. A surgical simulator for peeling the inner limiting membrane during wet conditions.

    PubMed

    Omata, Seiji; Someya, Yusei; Adachi, Shyn'ya; Masuda, Taisuke; Hayakawa, Takeshi; Harada, Kanako; Mitsuishi, Mamoru; Totsuka, Kiyohito; Araki, Fumiyuki; Takao, Muneyuki; Aihara, Makoto; Arai, Fumihito

    2018-01-01

    The present study was performed to establish a novel ocular surgery simulator for training in peeling of the inner limited membrane (ILM). This simulator included a next-generation artificial ILM with mechanical properties similar to the natural ILM that could be peeled underwater in the same manner as in actual surgery. An artificial eye consisting of a fundus and eyeball parts was fabricated. The artificial eye was installed in the eye surgery simulator. The fundus part was mounted in the eyeball, which consisted of an artificial sclera, retina, and ILM. To measure the thickness of the fabricated ILM on the artificial retina, we calculated the distance of the step height as the thickness of the artificial ILM. Two experienced ophthalmologists then assessed the fabricated ILM by sensory evaluation. The minimum thickness of the artificial ILM was 1.9 ± 0.3 μm (n = 3). We were able to perform the peeling task with the ILM in water. Based on the sensory evaluation, an ILM with a minimum thickness and 1000 degrees of polymerization was suitable for training. We installed the eye model on an ocular surgery simulator, which allowed for the performance of a sequence of operations similar to ILM peeling. In conclusion, we developed a novel ocular surgery simulator for ILM peeling. The artificial ILM was peeled underwater in the same manner as in an actual operation.

  4. Extraction of bromelain from pineapple peels.

    PubMed

    Ketnawa, S; Chaiwut, P; Rawdkuen, S

    2011-08-01

    Large amount of pineapple peels (by-products) is left over after processing and they are a potential source for bromelain extraction. Distilled water (DI), DI containing cysteine and ethylenediaminetetraacetic acid (EDTA) (DI-CE), sodium phosphate buffer pH 7.0 (PB) and PB containing cysteine and EDTA (PB-CE) were used as extractants for bromelain from the pineapple peels. The highest bromelain activity was obtained when it was extracted with PB-CE (867 and 1032 units for Nang Lae and Phu Lae cultv, respectively). The PB could maintain the pH of the extract (pH 5.1-5.7) when compared with others. Under sodium dodecyl sulfate polyacrylamide gel electrophoresis, the extract showed protein bands in the range 24-28 kDa. The protein band with a molecular weight of ∼28 kDa exposed the clear zone on blue background under the casein-substrate gel electrophoresis. The effects of the bromelain extract on the protein patterns of beef, chicken and squid muscles were also determined. Trichloroacetic acid soluble peptide content of all the treated muscles increased when the amount of bromelain extract increased. Decrease in myosin heavy chains and actin was observed in all the muscle types when bromelain extract was used. The best extractant for bromelain from pineapple peels was PB-CE. Moreover, bromelain extract could be used as a muscle food tenderizing agent in food industries.

  5. Chemical Peels in Melasma: A Review with Consensus Recommendations by Indian Pigmentary Expert Group

    PubMed Central

    Sarkar, Rashmi; Arsiwala, Shehnaz; Dubey, Neha; Sonthalia, Sidharth; Das, Anupam; Arya, Latika; Gokhale, Narendra; Torsekar, RG; Somani, VK; Majid, Imran; Godse, Kiran; Ravichandran, G.; Singh, Mohan; Aurangabadkar, Sanjeev; Salim, T; Shah, Swapnil; Sinha, Surabhi

    2017-01-01

    Melasma is a notorious dermatosis, often resistant to treatment. Chemical peeling constitutes an acceptable option of management of melasma (of any type and duration). In this article, as a group of experts from Pigmentary Disorders Society (PDS) in collaboration with South Asian Pigmentary Forum (SPF), we have tried to elaborate the various chemical peeling agents for the treatment of melasma. Besides, we have reviewed the indications, mechanism of action, rationality and the detailed procedure of peeling. The evidence in favor of various peeling agents have been summarized as well. PMID:29263530

  6. Chemical Peels in Melasma: A Review with Consensus Recommendations by Indian Pigmentary Expert Group.

    PubMed

    Sarkar, Rashmi; Arsiwala, Shehnaz; Dubey, Neha; Sonthalia, Sidharth; Das, Anupam; Arya, Latika; Gokhale, Narendra; Torsekar, R G; Somani, V K; Majid, Imran; Godse, Kiran; Ravichandran, G; Singh, Mohan; Aurangabadkar, Sanjeev; Salim, T; Shah, Swapnil; Sinha, Surabhi

    2017-01-01

    Melasma is a notorious dermatosis, often resistant to treatment. Chemical peeling constitutes an acceptable option of management of melasma (of any type and duration). In this article, as a group of experts from Pigmentary Disorders Society (PDS) in collaboration with South Asian Pigmentary Forum (SPF), we have tried to elaborate the various chemical peeling agents for the treatment of melasma. Besides, we have reviewed the indications, mechanism of action, rationality and the detailed procedure of peeling. The evidence in favor of various peeling agents have been summarized as well.

  7. "Self-Peel-Off" Transfer Produces Ultrathin Polyvinylidene-Fluoride-Based Flexible Nanodevices.

    PubMed

    Tai, Yanlong; Lubineau, Gilles

    2017-04-01

    Here, a new strategy, self-peel-off transfer, for the preparation of ultrathin flexible nanodevices made from polyvinylidene-fluoride (PVDF) is reported. In this process, a functional pattern of nanoparticles is transferred via peeling from a temporary substrate to the final PVDF film. This peeling process takes advantage of the differences in the work of adhesion between the various layers (the PVDF layer, the nanoparticle-pattern layer and the substrate layer) and of the high stresses generated by the differential thermal expansion of the layers. The work of adhesion is mainly guided by the basic physical/chemical properties of these layers and is highly sensitive to variations in temperature and moisture in the environment. The peeling technique is tested on a variety of PVDF-based functional films using gold/palladium nanoparticles, carbon nanotubes, graphene oxide, and lithium iron phosphate. Several PVDF-based flexible nanodevices are prepared, including a single-sided wireless flexible humidity sensor in which PVDF is used as the substrate and a double-sided flexible capacitor in which PVDF is used as the ferroelectric layer and the carrier layer. Results show that the nanodevices perform with high repeatability and stability. Self-peel-off transfer is a viable preparation strategy for the design and fabrication of flexible, ultrathin, and light-weight nanodevices.

  8. Key Microbiota Identification Using Functional Gene Analysis during Pepper (Piper nigrum L.) Peeling.

    PubMed

    Zhang, Jiachao; Hu, Qisong; Xu, Chuanbiao; Liu, Sixin; Li, Congfa

    2016-01-01

    Pepper pericarp microbiota plays an important role in the pepper peeling process for the production of white pepper. We collected pepper samples at different peeling time points from Hainan Province, China, and used a metagenomic approach to identify changes in the pericarp microbiota based on functional gene analysis. UniFrac distance-based principal coordinates analysis revealed significant changes in the pericarp microbiota structure during peeling, which were attributed to increases in bacteria from the genera Selenomonas and Prevotella. We identified 28 core operational taxonomic units at each time point, mainly belonging to Selenomonas, Prevotella, Megasphaera, Anaerovibrio, and Clostridium genera. The results were confirmed by quantitative polymerase chain reaction. At the functional level, we observed significant increases in microbial features related to acetyl xylan esterase and pectinesterase for pericarp degradation during peeling. These findings offer a new insight into biodegradation for pepper peeling and will promote the development of the white pepper industry.

  9. Key Microbiota Identification Using Functional Gene Analysis during Pepper (Piper nigrum L.) Peeling

    PubMed Central

    Xu, Chuanbiao; Liu, Sixin; Li, Congfa

    2016-01-01

    Pepper pericarp microbiota plays an important role in the pepper peeling process for the production of white pepper. We collected pepper samples at different peeling time points from Hainan Province, China, and used a metagenomic approach to identify changes in the pericarp microbiota based on functional gene analysis. UniFrac distance-based principal coordinates analysis revealed significant changes in the pericarp microbiota structure during peeling, which were attributed to increases in bacteria from the genera Selenomonas and Prevotella. We identified 28 core operational taxonomic units at each time point, mainly belonging to Selenomonas, Prevotella, Megasphaera, Anaerovibrio, and Clostridium genera. The results were confirmed by quantitative polymerase chain reaction. At the functional level, we observed significant increases in microbial features related to acetyl xylan esterase and pectinesterase for pericarp degradation during peeling. These findings offer a new insight into biodegradation for pepper peeling and will promote the development of the white pepper industry. PMID:27768750

  10. [Banana peel: a possible source of infection in the treatment of nipple fissures].

    PubMed

    Novak, Franz Reis; de Almeida, João Aprígio Guerra; de Souza e Silva, Rosana

    2003-01-01

    To study the microbiology of banana peel being sold in the city of Rio de Janeiro, in an attempt to determine the possibility that the peel may represent a source of infection for women who use it to treat nipple fissures. The following microorganisms were studied in 20 banana peel samples: mesophiles, total coliforms, fecal coliforms, Pseudomonas aeruginosa, lipolytic and proteolytic microorganisms, molds and yeasts, lactic bacteria, and coagulase-positive staphylococcus. The microbiological analyses revealed the occurrence of several typical groups of microorganisms, with the following distribution of positive results being detected in banana peel samples: mesophiles, 100%; total coliforms, 20%; coagulase-positive staphylococcus, 25%; molds and yeasts, 30%; proteolytic microorganisms, 70%; lipolytic microorganisms, 30%, and lactic bacteria, 95%. Fecal coliforms and Pseudomonas aeruginosa were not isolated. The results show the presence of potentially pathogenic microorganisms in levels which could compromise the microbiological quality of the banana peel. Its use for the treatment of nipple fissures can initiate an infectious process.

  11. Identification of epoxybergamottin as a CYP3A4 inhibitor in grapefruit peel.

    PubMed

    Wangensteen, H; Molden, E; Christensen, H; Malterud, K E

    2003-02-01

    The oral availability of many drugs metabolised by the enzyme cytochrome P(450) 3A4 (CYP3A4) is increased if co-administered with grapefruit juice. Extracts from grapefruit peel have also demonstrated inhibitory activity and, during commercial manufacturing of grapefruit juice, inhibitory components might be squeezed into the juice from the peel. Thus, the aim of this in vitro study was to identify CYP3A4 inhibitors in grapefruit peel. Grapefruit peel was extracted with diethyl ether, and the extract was further fractionated by normal-phase chromatography. Fractions demonstrating significant CYP3A4 inhibitory activity, as measured by the relative reduction in N-demethylation of diltiazem in transfected human liver epithelial cells, were subsequently separated by preparative thin-layer chromatography. Constituents of the fractions and isolated compounds were identified by nuclear magnetic resonance spectroscopy. Analysis of diltiazem and N-demethyl-diltiazem was performed using high-performance liquid chromatography. Of the identified components in grapefruit peel, only epoxybergamottin demonstrated a concentration-dependent inhibition of the CYP3A4-mediated N-demethylation of diltiazem. The IC(50) value was calculated to be 4.2+/-1.1 micro M. Coumarins without the furan ring and flavonoids isolated from grapefruit peel did not interfere with the metabolism of diltiazem. The results indicated the presence of other CYP3A4 inhibitors in grapefruit peel, but these agents were lost during the purification process excluding their identification. The furanocoumarin epoxybergamottin, present in grapefruit peel, is an inhibitor of CYP3A4. In commercial manufacturing of grapefruit juice, epoxybergamottin is possibly distributed into the juice. During manufacturing, however, epoxybergamottin may be hydrolysed to 6',7'-dihydroxybergamottin, which has been suggested as an important CYP3A4 inhibitor in grapefruit juice.

  12. Hypercalciuria in a child with acral peeling skin syndrome: a case report.

    PubMed

    Gorczyca, Daiva; Węgłowska, Jolanta; Prescha, Anna; Woźniak, Zdzisław; Nesteruk, Dominika; Wertheim-Tysarowska, Katarzyna; Śmigiel, Robert

    2015-01-01

    We present a case of 3-year-old Caucasian boy who developed monthly cyclic attacks of skin peeling of the palms and soles over 1.5 years. The skin peeling was associated with hypercalciuria. No mutation was present in TGM5 and CSTA genes, but the typical clinical picture and the biopsy from flaccid blisters on the feet confirmed the acral peeling skin syndrome (APSS). The possible associations of rare genetic disorders and metabolic conditions in the course of APSS need to be investigated.

  13. Carbonised jackfruit peel as an adsorbent for the removal of Cd(II) from aqueous solution.

    PubMed

    Inbaraj, B Stephen; Sulochana, N

    2004-08-01

    The fruit of the jack (Artocarpus heterophyllus) is one of the popular fruits in India, where the total area under this fruit is about 13,460 ha. A significant amount of peel (approximately 2,714-11,800 kg per tree per year) is discarded as agricultural waste, as apart from its use as a table fruit, it is popular in many culinary preparations. Treatment of jackfruit peel with sulphuric acid produced a carbonaceous product which was used to study its efficiency as an adsorbent for the removal of Cd(II) from aqueous solution. Batch experiments were performed as a function of process parameters; agitation time, initial metal concentration, adsorbent concentration and pH. Kinetic analyses made with Lagergren pseudo-first-order, Ritchie second-order and modified Ritchie second-order models showed better fits with modified Ritchie second-order model. The Langmuir-Freundlich (Sips equation) model best defined the experimental equilibrium data among the three isotherm models (Freundlich, Langmuir and Langmuir-Freundlich) tested. Taking a particular metal concentration, the optimum dose and pH required for the maximum metal removal was established. A complete recovery of the adsorbed metal ions from the spent adsorbent was achieved by using 0.01 M HCl.

  14. Antioxidant, antibacterial and antiproliferative activities of pumpkin (cucurbit) peel and puree extracts - an in vitro study.

    PubMed

    Asif, Muhammad; Naqvi, Syed Ali Raza; Sherazi, Tauqir A; Ahmad, Matloob; Zahoor, Ameer Fawad; Shahzad, Sohail Anjum; Hussain, Zaib; Mahmood, Hassan; Mahmood, Nasir

    2017-07-01

    Natural resources right from the beginning of the human civilization has paved the way to human being to combat different challenges. The big challenge was to safe the human being from diseases and shortage of food. Plants helped the man in both areas very efficiently. No doubt when plants are used as food actually we are also taking lot of compounds of medicinal values in an excellent combination which naturally reduce the risk of diseases. Extraction and purification of several medicinally important compounds also gave the way to develop pharmaceutical industry in addition to its own therapeutic effects against different lethal diseases. Pumpkin is one of the several medicinal important vegetables used in different way on the behalf of its admirable power to combat different diseases. Antioxidant and biological studies showed very important results. A good coherence was found among extraction yield (10.52 to 18.45%), total phenolics (1.13 to 6.78 mg GAE/100g), total flavonoids (0.23 to 0.72mg CE/100g) and antioxidant potential (≻70%). Antibacterial assays of peel and puree extracts advocated good potential to stop the growth and division of pathogenic bacteria. Further biological activity study was carried out using MDBK cancer cell line. The growth inhibitory effect on cancer cell line using MTT assay showed methanol extracts of peel and puree both remained efficient to inhibit growth (≻35%) and cell division of cancer cells. Our results showed that extracts of pumpkin puree and its waste, peel, may be utilize to prepare functional food against pathogenic born diseases and most active compounds may also be extracted, concentrated and converted into tablets or suspension form for therapeutic purposes.

  15. Cereal bars produced with banana peel flour: evaluation of acceptability and sensory profile.

    PubMed

    Carvalho, Vania Silva; Conti-Silva, Ana Carolina

    2018-01-01

    A mixture design was used to investigate the effects of banana peel flour, rice flakes and oat flour on sensory acceptability of cereal bars, with subsequent evaluation of sensory profile of products identified as having high acceptability. Regions of greater response for acceptability of the cereal bars, which are dependent on the three investigated components, were found. Although having good acceptability, sensory profiles of cereal bars were different. A cereal bar with the lowest quantity of banana peel flour was described as having a higher amount of rice flakes, chewiness and crispness, while formulations with intermediate and highest quantities of banana peel flour were described by darker color, higher banana aroma and bitter taste. Contrary to expectations, banana flavor of cereal bar with highest quantity of banana peel flour was lower than cereal bars with intermediate quantities. Cereal bars were not different in terms of hardness and adhesiveness and they also had a similar sweet taste and oat flavor. The use of banana peel flour in production of cereal bars is feasible and, even with different sensory profiles, cereal bars with banana peel flour are acceptable, which may favor the development of new products for different market niches. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  16. Anti-diabetic effect of dietary mango (Mangifera indica L.) peel in streptozotocin-induced diabetic rats.

    PubMed

    Gondi, Mahendranath; Basha, Shaik Akbar; Bhaskar, Jamuna J; Salimath, Paramahans V; Rao, Ummiti J S Prasada

    2015-03-30

    In the present study, the composition of mango peel powder (MPP) collected from the mango pulp industry was determined and the effect of MPP on ameliorating diabetes and its associated complications was studied. Mango peel was rich in polyphenols, carotenoids and dietary fibre. Peel extract contained various bioactive compounds and was found to be rich in soluble dietary fibre. Peel extract exhibited antioxidant properties and protected against DNA damage. Therefore, the effect of peel on ameliorating diabetes was investigated in a rat model of diabetes. A significant increase in urine sugar, urine volume, fasting blood glucose, total cholesterol, triglycerides and low density lipoprotein, and decrease in high density lipoprotein were observed in the rats; however, these parameters were ameliorated in diabetic rats fed with diet supplemented with mango peel at 5% and 10% levels in basal diet. Treatment of diabetic rats with MPP increased antioxidant enzyme activities and decreased lipid peroxidation in plasma, kidney and liver compared to untreated diabetic rats. Glomerular filtration rate and microalbuminuria levels were ameliorated in MPP treated diabetic group. Mango peel, a by-product, can be used as an ingredient in functional and therapeutic foods. © 2014 Society of Chemical Industry.

  17. Thermally assisted peeling of an elastic strip in adhesion with a substrate via molecular bonds

    NASA Astrophysics Data System (ADS)

    Qian, Jin; Lin, Ji; Xu, Guang-Kui; Lin, Yuan; Gao, Huajian

    A statistical model is proposed to describe the peeling of an elastic strip in adhesion with a flat substrate via an array of non-covalent molecular bonds. Under an imposed tensile peeling force, the interfacial bonds undergo diffusion-type transition in their bonding state, a process governed by a set of probabilistic equations coupled to the stretching, bending and shearing of the elastic strip. Because of the low characteristic energy scale associated with molecular bonding, thermal excitations are found to play an important role in assisting the escape of individual molecular bonds from their bonding energy well, leading to propagation of the peeling front well below the threshold peel-off force predicted by the classical theories. Our study establishes a link between the deformation of the strip and the spatiotemporal evolution of interfacial bonds, and delineates how factors like the peeling force, bending rigidity of the strip and binding energy of bonds influence the resultant peeling velocity and dimensions of the process zone. In terms of the apparent adhesion strength and dissipated energy, the bond-mediated interface is found to resist peeling in a strongly rate-dependent manner.

  18. Developing a MOOC Initiative: Lessons Learnt from the Universitat Politecnica de Valencia Experience

    ERIC Educational Resources Information Center

    Despujol, Ignacio; Castaneda, Linda; Turro, Carlos

    2018-01-01

    Universitat Politecnica de Valencia (UPV) was the European institution with more MOOC course runs done by December 2016. This paper describes and analyses the decisionmaking process, and rationale of the development of this low budget real MOOC institutional initiative carried out by a traditional higher educational medium sized institution. This…

  19. Banana peel: a green and economical sorbent for the selective removal of Cr(VI) from industrial wastewater.

    PubMed

    Memon, Jamil R; Memon, Saima Q; Bhanger, Muhammad I; El-Turki, Adel; Hallam, Keith R; Allen, Geoffrey C

    2009-05-01

    This study describes the use of banana peel, a commonly produced fruit waste, for the removal of Cr(VI) from industrial wastewater. The parameters pH, contact time, initial metal ion concentration, and temperature were investigated and the conditions resulting in rapid and efficient adsorption (95% within 10 min) were determined. The binding of metal ions was found to be pH dependent with the optimal sorption occurring at pH 2. The retained species were eluted with 5 mL of 2M H(2)SO(4). To elucidate the mechanism of the process, total amounts of chromium and Cr(VI) were analyzed using flame atomic absorption and ultraviolet-visible (UV-vis) spectroscopic techniques, respectively. The Langmuir and Dubinin-Radushkevich (D-R) isotherms were used to describe the partitioning behavior for the system at different temperatures. Kinetics and thermodynamics of Cr(VI) removal by banana peel were also studied. The influence of diverse ions on the sorption behavior revealed that only Fe(II) ions (of those tested) suppressed the sorption of Cr(VI) ions to some extent. The method was applied for the removal of Cr(VI) from industrial wastewater.

  20. Predictive modeling of infrared radiative heating in tomato dry-peeling process: Part I. Model development

    USDA-ARS?s Scientific Manuscript database

    Infrared (IR) dry-peeling has emerged as an effective non-chemical alternative to conventional lye and steam methods of peeling tomatoes. Successful peel separation induced by IR radiation requires the delivery of a sufficient amount of thermal energy onto tomato surface in a very short duration. Th...

  1. Using Apple Peel Sections To Study Plant Cells and Water Relations.

    ERIC Educational Resources Information Center

    Silvius, John E.; Eckart, Christopher P.

    1997-01-01

    Suggests the cells of an apple peel as a plant species that can further enhance the plant cell laboratory. Describes the structure of apple peel cells and the benefits of including them in studies of plant cells. Suggests questions to stimulate further investigations for open-ended laboratories or independent studies. (PVD)

  2. Health effects of the 2012 Valencia (Spain) wildfires on children in a cohort study.

    PubMed

    Vicedo-Cabrera, Ana M; Esplugues, Ana; Iñíguez, Carmen; Estarlich, Marisa; Ballester, Ferran

    2016-06-01

    In July 2012, two simultaneous wildfires burnt a big area in Valencia (Spain), where a birth cohort study (INMA) is being developed. The heavy smoke covered the whole INMA study area for several days. We aimed at evaluating the 2012 Valencia wildfire effects on the health of children enrolled in the INMA-Valencia cohort. Two weeks after the extinction of the wildfires, a phone survey was conducted and finally 460 individuals were enrolled. We considered a wildfire period (12-day interval when they were active) and a control period (12-day interval just before wildfires). Parents were asked about respiratory symptoms experienced during both periods, and during wildfires only about the preventive measures adopted and the perception of exposure, along with individual data collected through the different follow-up surveys of the cohort. Conditional logistic regression models were applied, and we included interaction terms for asthma/rhinitis and level of perception of exposure; 82.4 % perceived smoke smell outdoors, 40 % indoors and more than 90 % of the families observed the presence of ash. An adjusted odds ratio of 3.11 [95 % confidence interval 1.62-5.97] for itchy/watery eyes and 3.02 [1.41-6.44] for sore throat was obtained. Significant interaction terms for rhinitis and asthma in itchy/watery eyes and sneezing, and only asthma for sore throat were obtained. Exposure to wildfire smoke was associated with increased respiratory symptoms in this child population, particularly affecting susceptible individuals with asthma or rhinitis.

  3. Application of banana peels nanosorbent for the removal of radioactive minerals from real mine water.

    PubMed

    Oyewo, Opeyemi A; Onyango, Maurice S; Wolkersdorfer, Christian

    2016-11-01

    Transformation of agricultural waste such as banana peels into a valuable sorbent material has been proven effective and efficient in wastewater treatment. Further, transformation into nanosorbent to enhance the removal capacity of actinides (uranium and thorium) from synthetic and real mine water is extensively investigated in this study. The nanosorbent samples before and after adsorption were characterised by X-ray diffraction (XRD), Fourier transform infra-red (FTIR), zetasizer nanoseries and scanning electron microscopy (SEM) while the amount of radioactive substances adsorbed was determined by inductively coupled plasma optical emission spectroscopy. Results revealed that there was a crystallite size and particle size reduction from 108 to 12 nm and <65,000 nm to <25 nm respectively as a function of milling time. Furthermore, appearance and disappearance of nanofibers via milling was noticed during structural analysis. The functional groups responsible for the banana peels capability to coordinate and remove metal ions were identified at absorption bands of 1730 cm -1 (carboxylic groups) and 889 cm -1 (amine groups) via FTIR analysis. Equilibrium isotherm results demonstrated that the adsorption process was endothermic for both uranium and thorium. The Langmuir maximum adsorption capacity was 27.1 mg g -1 , 34.13 mg g -1 for uranium and 45.5 mg g -1 , 10.10 mg g -1 for thorium in synthetic and real mine water, respectively. The results obtained indicate that nanostructured banana peels is a potential adsorbent for the removal of radioactive substances from aqueous solution and also from real mine water. However, the choice of this sorbent material for any application depends on the composition of the effluent to be treated. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Comparisons of foveal thickness and slope after macular hole surgery with and without internal limiting membrane peeling

    PubMed Central

    Ohta, Kouichi; Sato, Atsuko; Senda, Nami; Fukui, Emi

    2018-01-01

    Background We have shown that the foveal contour was asymmetrical after idiopathic macular hole (MH) closure by pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling. The purpose of this study was to determine whether these morphological changes differ in eyes after PPV without ILM peeling. Methods Ten eyes of 10 patients that underwent PPV without ILM peeling and 12 eyes of 11 patients with ILM peeling were studied. The MH in all eyes was <400 µm in diameter. Six months after the PPV, the macular thickness and foveal slope around the closed MH were determined by spectral-domain optical coherence tomography. The thickness of the ganglion cell complex was measured by another spectral-domain optical coherence tomography instrument >6 months after the surgery. Results The mean parafoveal retinal thickness in the non-peeled group was 367.1 µm in the nasal (N), 353.0 µm in the temporal (T), 366.9 µm in the superior (S), and 357.3 µm in the inferior (I) sectors. The T, S, and I sectors were significantly thicker than the corresponding sectors in the ILM peeled group (p=0.0008, 0.003, and 0.03, respectively). The mean ganglion cell complex was thicker not only in the N sector but also in the T sector in the non-peeled group. The mean retinal slopes in the non-peeled group (N, 40.2°; T, 37.6°; S, 41.2°; I, 39.5°) were flatter than those in the peeled group (N, 52.3°; T, 43.6°; S, 50.8°; I, 51.9°; p=0.009, 0.09, 0.008, and 0.017, respectively). Conclusion The symmetrical fovea after MH surgery in the non-ILM peeled eyes indicates that the asymmetrical fovea after ILM peeling was probably due to the ILM peeling. PMID:29588571

  5. Comparisons of foveal thickness and slope after macular hole surgery with and without internal limiting membrane peeling.

    PubMed

    Ohta, Kouichi; Sato, Atsuko; Senda, Nami; Fukui, Emi

    2018-01-01

    We have shown that the foveal contour was asymmetrical after idiopathic macular hole (MH) closure by pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling. The purpose of this study was to determine whether these morphological changes differ in eyes after PPV without ILM peeling. Ten eyes of 10 patients that underwent PPV without ILM peeling and 12 eyes of 11 patients with ILM peeling were studied. The MH in all eyes was <400 µm in diameter. Six months after the PPV, the macular thickness and foveal slope around the closed MH were determined by spectral-domain optical coherence tomography. The thickness of the ganglion cell complex was measured by another spectral-domain optical coherence tomography instrument >6 months after the surgery. The mean parafoveal retinal thickness in the non-peeled group was 367.1 µm in the nasal (N), 353.0 µm in the temporal (T), 366.9 µm in the superior (S), and 357.3 µm in the inferior (I) sectors. The T, S, and I sectors were significantly thicker than the corresponding sectors in the ILM peeled group ( p =0.0008, 0.003, and 0.03, respectively). The mean ganglion cell complex was thicker not only in the N sector but also in the T sector in the non-peeled group. The mean retinal slopes in the non-peeled group (N, 40.2°; T, 37.6°; S, 41.2°; I, 39.5°) were flatter than those in the peeled group (N, 52.3°; T, 43.6°; S, 50.8°; I, 51.9°; p =0.009, 0.09, 0.008, and 0.017, respectively). The symmetrical fovea after MH surgery in the non-ILM peeled eyes indicates that the asymmetrical fovea after ILM peeling was probably due to the ILM peeling.

  6. Modeling Transfer of Vibrio Parahaemolyticus During Peeling of Raw Shrimp.

    PubMed

    Xiao, Xingning; Pang, Haiying; Wang, Wen; Fang, Weihuan; Fu, Yingchun; Li, Yanbin

    2018-03-01

    This study aimed to qualify the transfer of Vibrio parahaemolyticus during the shrimp peeling process via gloves under 3 different scenarios. The 1st 2 scenarios provided quantitative information for the probability distribution of bacterial transfer rates from (i) contaminated shrimp (6 log CFU/g) to non-contaminated gloves (Scenario 1) and (ii) contaminated gloves (6 log CFU/per pair) to non-contaminated shrimp (Scenario 2). In Scenario 3, bacterial transfer from contaminated shrimp to non-contaminated shrimp in the shrimp peeling process via gloves was investigated to develop a predictive model for describing the successive bacterial transfer. The range of bacterial transfer rate (%) in Scenarios 1 and 2 was 7% to 91.95% and 0.04% to 12.87%, respectively, indicating that the bacteria can be transferred from shrimp to gloves much easier than that from gloves to shrimp. A Logistic (1.59, 0.14) and Triangle distribution (-1.61, 0.12, 1.32) could be used to describe the bacterial transfer rate in Scenarios 1 and 2, respectively. In Scenario 3, a continuously decay patterning with fluctuations as the peeling progressed has been observed at all inoculation levels of the 1st shrimp (5, 6, and 7 log CFU/g). The bacteria could be transferred easier at 1st few peels, and the decreasing bacterial transfer was found in later phase. Two models (exponential and Weibull) could describe the successive bacterial transfer satisfactorily (pseudo-R 2 > 0.84, RMSE < 1.23, SEP < 10.37). The result of this study can provide information regarding cross-contamination events in the seafood factory. This study presented that Vibrio parahaemolyticus cross-contamination could be caused by gloves during the shrimp peeling process. The bacterial transfer rate distribution and predictive model derived from this work could be used in risk assessment of V. parahaemolyticus to ensure peeled shrimp safety. © 2018 Institute of Food Technologists®.

  7. The Peel Inlet-Harvey Estuary Study.

    ERIC Educational Resources Information Center

    Walker, Warren; Black, Ronald

    1979-01-01

    Describes how the department of physics of the Western Australian Institute of Technology (WAIT) has been involved in the Peel Inlet-Harvey Estuary study. An appendix which presents the departmental approach to curriculum matters is also included. (HM)

  8. Quercetin, a functional compound of onion peel, remodels white adipocytes to brown-like adipocytes.

    PubMed

    Lee, Sang Gil; Parks, John S; Kang, Hye Won

    2017-04-01

    Adipocyte browning is a promising strategy for obesity prevention. Using onion-peel-derived extracts and their bioactive compounds, we demonstrate that onion peel, a by-product of onion, can change the characteristics of white adipocytes to those of brown-like adipocytes in the white adipose tissue of mice and 3T3-L1 cells. The expression of the following brown adipose tissue-specific genes was increased in the retroperitoneal and subcutaneous adipose tissues of 0.5% onion-peel-extract-fed mice: PR domain-containing 16, peroxisome proliferator-activated receptor gamma coactivator 1α, uncoupling protein 1, fibroblast growth factor 21 and cell death-inducing DFFA-like effector. In 3T3-L1 adipocytes, onion peel extract induced the expression of brown adipose tissue-specific genes and increased the expression of carnitine palmitoyltransferase 1α. This effect was supported by decreased lipid levels and multiple small-sized lipid droplets. The ethyl acetate fraction of the onion peel extract that contained the highest proportion of hydrophobic molecules showed the same browning effect in 3T3-L1 adipocytes. A high-performance liquid chromatography analysis further identified quercetin as a functional compound in the browning effect of onion peel. The quercetin-associated browning effect was mediated in part by the activation of AMP-activated protein kinase. In summary, our study provides the first demonstration of the browning effects of onion peel and quercetin using both animal and cell models. This result indicates that onion peel has the potential to remodel the characteristics of white adipocytes to those of brown-like adipocytes. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. In vitro protective effects of two extracts from bergamot peels on human endothelial cells exposed to tumor necrosis factor-alpha (TNF-alpha).

    PubMed

    Trombetta, Domenico; Cimino, Francesco; Cristani, Mariateresa; Mandalari, Giuseppina; Saija, Antonella; Ginestra, Giovanna; Speciale, Antonio; Chirafisi, Joselita; Bisignano, Giuseppe; Waldron, Keith; Narbad, Arjan; Faulds, Craig B

    2010-07-28

    Bergamot ( Citrus bergamia Risso) is a less commercialized Citrus fruit, mainly used for its essential oil extracted from the peel. Bergamot peel (BP) represents about 60% of the processed fruits and is regarded as primary waste. However, it contains good amounts of useful compounds, such as pectins and flavonoids. Many of the bioactivities of Citrus flavonoids appear to impact vascular endothelial cells. Herein, we report the protective effect of two flavonoid-rich extracts from BP (endowed with radical-scavenging properties and lacking genotoxic activity) against alterations in cell modifications induced by the pleiotropic inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) on human umbilical vein endothelial cells (HUVECs), as demonstrated by monitoring intracellular levels of malondialdehyde/4-hydroxynonenal, reduced and oxidized glutathione and superoxide dismutase activity, and the activation status of nuclear factor-kappaB (NF-kappaB). Thus, BP appears to be a potential source of natural antioxidant/anti-inflammatory phytocomplexes to be employed as ingredients of nutraceutical products or functional foods.

  10. An Ap"peel"ing Activity

    ERIC Educational Resources Information Center

    Urich, Joshua A.; Sasse, Elizabeth A.

    2011-01-01

    This article describes a hands-on mathematics activity wherein students peel oranges to explore the surface area and volume of a sphere. This activity encourages students to make conjectures and hold mathematical discussions with both their peers and their teacher. Moreover, students develop formulas for the surface area and volume of a sphere…

  11. Chemical Mapping of Essential Oils, Flavonoids and Carotenoids in Citrus Peels by Raman Microscopy.

    PubMed

    Yang, Ying; Wang, Xiaohe; Zhao, Chengying; Tian, Guifang; Zhang, Hua; Xiao, Hang; He, Lili; Zheng, Jinkai

    2017-12-01

    Citrus peels, by-products in large quantity, are rich in various functional and beneficial components which have wide applications. Chemical analysis of these components in citrus peels is an important step to determine the usefulness of the by-products for further applications. In this study, we explored Raman microscopy for rapid, nondestructive, and in situ chemical mapping of multiple main functional components from citrus peels. The relative amount and distribution in different locations (flavedo, albedo, and longitudinal section) of 3 main functional components (essential oils, carotenoids, and flavonoids) in citrus peels were systematically investigated. The distribution profiles of these components were heterogeneous on the peels and varied between different species of citrus peels. Essential oil was found mainly existed in the oil glands, while carotenoids were in the complementary location. Some flavonoids were observed in the oil glands. This study showed the capability of Raman microscopy for rapid and nondestructive analysis of multiple bio-components without extraction from plants. The information obtained from this study would assist the better production and application of the functional and beneficial components from citrus by products in an effective and sustainable manner. This study indicated the capability of Raman microscopy for rapid and nondestructive analysis of multiple bioactive components in plant tissues. The information obtained from the study would be valuable for developing effective and sustainable strategy of utilization of citrus peels for further applications. © 2017 Institute of Food Technologists®.

  12. Palaeogeographic implications of the Messinian surface in the Valencia trough, northwestern Mediterranean Sea

    NASA Astrophysics Data System (ADS)

    Escutia, C.; Maldonado, A.

    1992-03-01

    Sparker (3000 J and 8000 J) and multichannel seismic reflection profiles across the Valencia trough show a Messinian unconformity incised by numerous valleys. The main feature of this surface is a large valley that generally underlies the present Valencia valley and is deeply entrenched into the Miocene deposits. The size of this palaeo-valley ranges from 0.5 km wide and 15-100 m deep at its western end, to 1.6-2.8 km wide and 200-250 m deep downstream. An important tributary system is observed, with a main canyon (6-8 km wide and 150-200 m deep) draining the Ebro margin, as well as many other smaller valleys draining the Catalan and Balearic margins. Downstream, other tributaries underlie the present canyons of the Catalan margin. The location of the tributary system is controlled by the Early Miocene rift structures. The relief of the Messinian surface is affected by post-Miocene deformation that results from salt diapirism, extensional faulting and related volcanism. Late Neogene to Quaternary volcanic edifices cut the Messinian surface and coincide with large residual magnetic anomalies. Lower Pliocene to Quaternary salt diapirism in the abyssal plain north of Menorca has created a series of structural highs. Between these highs are deep interdiapiric troughs or basins that have become sediment depocentres during the Plio-Quaternary. The complex network of erosional valleys from the Valencia trough continental margin demonstrates that the valley system in the basin was not related to the refilling of the Mediterranean, but to the Iberian and Balearic margin palaeodrainage that developed during the Messinian desiccation. The presence of at least three erosional unconformities suggests that there were alternating periods of flooding and retreat of Atlantic water during Messinian time. The Messinian subaerial margin with erosional valleys contrasts sharply with the Pliocene-Quaternary marine margin with progradational turbidite systems.

  13. In vitro and In vivo Postprandial Glycemic Activity of Citrus limetta Peel Flour.

    PubMed

    Flores-Fernández, José Miguel; Barragán-Álvarez, Carla Patricia; Díaz-Martínez, Nestor Emmanuel; Villanueva-Rodríguez, Socorro; Padilla-Camberos, Eduardo

    2017-01-01

    Previous studies of Citrus spp. peel have shown hypoglycemic and antioxidant activities. Citrus limetta has been studied for its therapeutic properties. Diabetes mellitus (DM) is a health problem in Mexico and worldwide, that takes a vital importance due to its high incidence. Recently, scientists have searched natural sources to control the disease. In this study, we evaluated the in vitro hypoglycemic activity and in vivo postprandial glycemic effect of C. limetta peel flour by glucose adsorption and retardation assays as well as postprandial serum glucose levels using a group of female Balb-c mice, respectively. C. limetta peel flour showed a glucose adsorption capacity of 16.58 mM, having a similar effect regarding the positive control. The glucose diffusion in the dialysate was elevated, with a glucose dialysis retardation index of 33.79% in a period of 3 h, showing similar results to positive control. Postprandial serum glucose levels in the animal group treated with C. limetta peel flour showed a glucose level of 41.4 mg/dL, being this value significantly lower than negative control group and similar to positive control. Toxicity tests showed good tolerance to the dose of 2000 mg/kg. C. limetta peel flour could act as a source of functional compounds for the control of DM. Citrus limetta peel flour showed a glucose adsorption capacity similar to the positive controlThe glucose diffusion in the dialysate was elevated, showing similar results to positive controlPostprandial serum glucose levels in the animal group treated with C. limetta peel flour showed a glucose level significantly lower than negative control group and similar to positive controlToxicity tests showed good tolerance C. limetta peel flour could act as a source of functional compounds for the control of diabetes mellitus. Abbreviations used: CIATEJ: Center for Research and Assistance in Technology and Design of Jalisco; DM: Diabetes mellitus; FGC: Final glucose concentration; GDRI: Glucose

  14. In vitro and In vivo Postprandial Glycemic Activity of Citrus limetta Peel Flour

    PubMed Central

    Flores-Fernández, José Miguel; Barragán-Álvarez, Carla Patricia; Díaz-Martínez, Nestor Emmanuel; Villanueva-Rodríguez, Socorro; Padilla-Camberos, Eduardo

    2017-01-01

    Background: Previous studies of Citrus spp. peel have shown hypoglycemic and antioxidant activities. Citrus limetta has been studied for its therapeutic properties. Diabetes mellitus (DM) is a health problem in Mexico and worldwide, that takes a vital importance due to its high incidence. Recently, scientists have searched natural sources to control the disease. Materials and Methods: In this study, we evaluated the in vitro hypoglycemic activity and in vivo postprandial glycemic effect of C. limetta peel flour by glucose adsorption and retardation assays as well as postprandial serum glucose levels using a group of female Balb-c mice, respectively. Results: C. limetta peel flour showed a glucose adsorption capacity of 16.58 mM, having a similar effect regarding the positive control. The glucose diffusion in the dialysate was elevated, with a glucose dialysis retardation index of 33.79% in a period of 3 h, showing similar results to positive control. Postprandial serum glucose levels in the animal group treated with C. limetta peel flour showed a glucose level of 41.4 mg/dL, being this value significantly lower than negative control group and similar to positive control. Toxicity tests showed good tolerance to the dose of 2000 mg/kg. Conclusion: C. limetta peel flour could act as a source of functional compounds for the control of DM. SUMMARY Citrus limetta peel flour showed a glucose adsorption capacity similar to the positive controlThe glucose diffusion in the dialysate was elevated, showing similar results to positive controlPostprandial serum glucose levels in the animal group treated with C. limetta peel flour showed a glucose level significantly lower than negative control group and similar to positive controlToxicity tests showed good toleranceC. limetta peel flour could act as a source of functional compounds for the control of diabetes mellitus. Abbreviations used: CIATEJ: Center for Research and Assistance in Technology and Design of Jalisco; DM

  15. Model Uncertainties for Valencia RPA Effect for MINERvA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gran, Richard

    2017-05-08

    This technical note describes the application of the Valencia RPA multi-nucleon effect and its uncertainty to QE reactions from the GENIE neutrino event generator. The analysis of MINERvA neutrino data in Rodrigues et al. PRL 116 071802 (2016) paper makes clear the need for an RPA suppression, especially at very low momentum and energy transfer. That published analysis does not constrain the magnitude of the effect; it only tests models with and without the effect against the data. Other MINERvA analyses need an expression of the model uncertainty in the RPA effect. A well-described uncertainty can be used for systematics for unfolding, for model errors in the analysis of non-QE samples, and as input for fitting exercises for model testing or constraining backgrounds. This prescription takes uncertainties on the parameters in the Valencia RPA model and adds a (not-as-tight) constraint from muon capture data. For MINERvA we apply it as a 2D (more » $$q_0$$,$$q_3$$) weight to GENIE events, in lieu of generating a full beyond-Fermi-gas quasielastic events. Because it is a weight, it can be applied to the generated and fully Geant4 simulated events used in analysis without a special GENIE sample. For some limited uses, it could be cast as a 1D $Q^2$ weight without much trouble. This procedure is a suitable starting point for NOvA and DUNE where the energy dependence is modest, but probably not adequate for T2K or MicroBooNE.« less

  16. Polygalacturonase production by AR2 pectinolytic bacteria through submerged fermentation of raja nangka banana peel (Musa paradisiaca var. formatypica) with variation of carbon source and pectin

    NASA Astrophysics Data System (ADS)

    Utami, R.; Widowati, E.; Ivenaria, A.; Mahajoeno, E.

    2017-04-01

    Polygalacturonase (EC 3.1.2.15) catalyzes the hydrolysis of α-1,4-glycosidic bonds on galacturonic acid. Polygalacturonase can be produced from AR2 pectinolytic bacteria isolated from orange peel and vegetable waste. Commonly cost production of enzymes were high. However, with the advancement of technology, enzymes can now be manufactured at a low cost. Production of enzymes in low cost media with agro-industrial waste is interesting. Raja nangka banana peel is agro-industrial waste that is uneconomic. Therefore, this material can be used as a pectin source in polygalacturonase production. Polygalacturonase was produced by AR2 pectinolytic bacteria with the addition of various carbon sources (1% glucose, 1% galactose, 1% lactose) and variation of pectin concentrations (5%; 7.5%; 10%). This study used submerged fermentation with a cultivation temperature of 55°C and an agitation speed of 144 rpm for a 48-h incubation time. The results showed that variation of carbon sources and pectin concentrations affected the production of polygalacturonase. After 48 h fermentation, the results showed that the number of cells of samples ranged from 8.3 to 9.445 log cells/mL; the used pectin of samples ranged from 87.170-93.745%; and the polygalacturonase activity of samples ranged from 0.030 to 0.151 U/mL. The highest polygalacturonase activity was obtained by production of polygalacturonase on 1% glucose and 10% pectin medium.

  17. Influence of lipid content and lipoxygenase on flavor volatiles in the tomato peel and flesh.

    PubMed

    Ties, Paige; Barringer, Sheryl

    2012-07-01

    Ten different varieties of tomatoes were separated into peel and flesh and each portion was measured separately. Headspace volatiles were measured in real time using selected ion flow tube mass spectrometry. Lipoxygenase activity was measured using the adsorption of conjugated dienes formed by lipoxygenase. Lipid was extracted and fatty acids were quantified using a gas chromatograph. Volatiles were significantly greater in the peel than flesh when there was a significant difference. The lipoxygenase activity of flesh and peel correlated with the volatiles produced by the lipoxygenase pathway. There was no correlation with other volatiles, which are not dependent on lipid oxidation by lipoxygenase. The lipoxygenase activity, total fatty acid content, and linolenic acid of the peel were greater than the flesh, which is directly related to an increase in fresh, green volatiles. Addition of exogenous lipoxygenase had no effect on lipoxygenase-derived volatiles formed. The addition of linoleic acid caused an increase in hexanal, 1-hexanol, and (E)-2-heptenal in the flesh and (E)-2-heptenal in the peel. Stored unrefrigerated peel had higher volatile concentrations, whereas refrigerated peel had significantly lower concentration than day 0. Storage decreased lipoxygenase activity in the unrefrigerated and refrigerated peel, but had no effect on the fatty acid content. Overall, linolenic acid was the most important to the formation of headspace volatiles, but lipoxygenase activity and unknown factors are also important. The peel of a tomato is most beneficial to the production of volatiles associated with the fresh aroma of tomatoes; therefore, it should be used in the processing of tomato products to produce a fresh, green aroma rather than being removed. Knowledge of the effects of lipoxygenase activity, total fatty acid content, and fatty acid profile on flavor volatiles will allow for better selection of a variety for raw consumption. © 2012 Institute of Food

  18. Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study.

    PubMed

    Bae, Byung Gi; Park, Chang Ook; Shin, Hyoseung; Lee, Soo Hyun; Lee, Yun Sun; Lee, Sang Ju; Chung, Kee Yang; Lee, Kwang Hoon; Lee, Ju Hee

    2013-02-01

    Salicylic acid was recently formulated in a hydroethanolic vehicle at a concentration of 20% to 30%. Salicylic acid has strong comedolytic effects because of its lipophilic nature. To compare the therapeutic efficacy and tolerability of salicylic acid peels with those of Jessner's solution peels in patients with acne vulgaris. Thirteen patients (13 men; mean age 22.6, range 20-28) with facial acne were enrolled. Jessner's solution was applied to one side of each patient's face and 30% salicylic acid to the other in three sessions at 2-week intervals. A blinded investigator counted noninflammatory and inflammatory lesions before treatment and 2 weeks after each treatment. Inflammatory and noninflammatory acne lesion counts decreased in proportion to the duration of treatment. Inflammatory acne lesion counts did not differ significantly between salicylic acid and Jessner's solution peels, although in terms of noninflammatory acne lesion counts, sites treated with salicylic acid showed significant improvement (p = .04), whereas those treated with Jessner's solution did not. We found that 30% salicylic acid peels were effective for inflammatory acne and more effective than Jessner's solution peels for treating noninflammatory acne. © 2012 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.

  19. Increased Retinal Thinning after Combination of Internal Limiting Membrane Peeling and Silicone Oil Endotamponade in Proliferative Diabetic Retinopathy.

    PubMed

    Kaneko, Hiroki; Matsuura, Toshiyuki; Takayama, Kei; Ito, Yasuki; Iwase, Takeshi; Ueno, Shinji; Nonobe, Norie; Yasuda, Shunsuke; Kataoka, Keiko; Terasaki, Hiroko

    2017-01-01

    The aim of this study was to examine the change in retinal thickness after vitrectomy with internal limiting membrane (ILM) peeling and/or silicone oil (SO) endotamponade in proliferative diabetic retinopathy (PDR). The actual amount and ratio of changes in the retinal thickness were calculated. Compared to control eyes in the ILM peeling (-)/SO (-) group, the central, superior inner, and temporal inner retina in the ILM peeling (+)/SO (-) group, the central and superior inner retina in the ILM peeling (-)/SO (+) group, and the central, inferior inner, temporal inner, and nasal inner retina in the ILM peeling (+)/SO (+) group showed a significant reduction of the retinal thickness. The central, superior inner, and temporal inner retina in the ILM peeling (+)/SO (-) group, the central and superior inner retina in the ILM peeling (-)/SO (+) group, and the central, superior inner, inferior inner, and temporal inner retina in the ILM peeling (+)/SO (+) group showed a significantly increased reduction rate of the retinal thickness compared to the control group. Macular retinal thinning in PDR was observed after ILM peeling and SO endotamponade, and it was increased by the combination of these 2 factors. © 2017 S. Karger AG, Basel.

  20. Antimicrobial activity of pomegranate peel extracts as affected by cultivar.

    PubMed

    Rosas-Burgos, Ema C; Burgos-Hernández, Armando; Noguera-Artiaga, Luis; Kačániová, Miroslava; Hernández-García, Francisca; Cárdenas-López, José L; Carbonell-Barrachina, Ángel A

    2017-02-01

    Some studies have reported that different parts of the pomegranate fruit, especially the peel, may act as potential antimicrobial agents and thus might be proposed as a safe natural alternative to synthetic antimicrobial agents. The high tannin content, especially punicalagin, found in pomegranate extracts, has been reported as the main compound responsible for such antimicrobial activity. Because the pomegranate peel chemical composition may vary with the type of cultivar (sweet, sour-sweet and sour), pomegranates may also differ with respect to their antimicrobial capacity. The extract from PTO8 pomegranate cultivar peel had the highest antimicrobial activity, as well as the highest punicalagins (α and β) and ellagic acid concentrations. In the results obtained from both antibacterial and antifungal activity studies, the sour-sweet pomegranate cultivar PTO8 showed the best antimicrobial activity, and the highest ellagic acid concentrations. The results of the present study suggest that ellagic acid content has a significant influence on the antimicrobial activity of the pomegranate extracts investigated. The pomegranate peel of the PTO8 cultivar is a good source of antifungal and antibacterial compounds, and may represent an alternative to antimicrobial agents of synthetic origin. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  1. Application of exogenous ethylene inhibits postharvest peel browning of ‘Huangguan’ pear

    USDA-ARS?s Scientific Manuscript database

    Peel browning disorder has an enormous impact on the exterior quality of ‘Huangguan’ pear whereas the underlying mechanism is still unclear. In this study, the effect of exogenous ethylene on peel browning of pear fruits stored at 0' was evaluated. Results showed that ethylene effectively inhibited ...

  2. Efficiency Evaluation of Food Waste Materials for the Removal of Metals and Metalloids from Complex Multi-Element Solutions

    PubMed Central

    Giuliano, Antonella; Astolfi, Maria Luisa; Congedo, Rossana; Masotti, Andrea; Canepari, Silvia

    2018-01-01

    Recent studies have shown the potential of food waste materials as low cost adsorbents for the removal of heavy metals and toxic elements from wastewater. However, the adsorption experiments have been performed in heterogeneous conditions, consequently it is difficult to compare the efficiency of the individual adsorbents. In this study, the adsorption capacities of 12 food waste materials were evaluated by comparing the adsorbents’ efficiency for the removal of 23 elements from complex multi-element solutions, maintaining homogeneous experimental conditions. The examined materials resulted to be extremely efficient for the adsorption of many elements from synthetic multi-element solutions as well as from a heavy metal wastewater. The 12 adsorbent surfaces were analyzed by Fourier transform infrared spectroscopy and showed different types and amounts of functional groups, which demonstrated to act as adsorption active sites for various elements. By multivariate statistical computations of the obtained data, the 12 food waste materials were grouped in five clusters characterized by different elements’ removal efficiency which resulted to be in correlation with the specific adsorbents’ chemical structures. Banana peel, watermelon peel and grape waste resulted the least selective and the most efficient food waste materials for the removal of most of the elements. PMID:29495363

  3. Efficiency Evaluation of Food Waste Materials for the Removal of Metals and Metalloids from Complex Multi-Element Solutions.

    PubMed

    Massimi, Lorenzo; Giuliano, Antonella; Astolfi, Maria Luisa; Congedo, Rossana; Masotti, Andrea; Canepari, Silvia

    2018-02-26

    Recent studies have shown the potential of food waste materials as low cost adsorbents for the removal of heavy metals and toxic elements from wastewater. However, the adsorption experiments have been performed in heterogeneous conditions, consequently it is difficult to compare the efficiency of the individual adsorbents. In this study, the adsorption capacities of 12 food waste materials were evaluated by comparing the adsorbents' efficiency for the removal of 23 elements from complex multi-element solutions, maintaining homogeneous experimental conditions. The examined materials resulted to be extremely efficient for the adsorption of many elements from synthetic multi-element solutions as well as from a heavy metal wastewater. The 12 adsorbent surfaces were analyzed by Fourier transform infrared spectroscopy and showed different types and amounts of functional groups, which demonstrated to act as adsorption active sites for various elements. By multivariate statistical computations of the obtained data, the 12 food waste materials were grouped in five clusters characterized by different elements' removal efficiency which resulted to be in correlation with the specific adsorbents' chemical structures. Banana peel, watermelon peel and grape waste resulted the least selective and the most efficient food waste materials for the removal of most of the elements.

  4. Skin rejuvenating effects of chemical peeling: a study in photoaged hairless mice.

    PubMed

    Han, Sung Hyup; Kim, Hong Jig; Kim, Si Yong; Kim, You Chan; Choi, Gwang Seong; Shin, Jeong Hyun

    2011-09-01

    Chemical peeling is a dermatologic treatment for skin aging. However, the mechanism by which the chemical peel achieves its results is not clear. We investigated the effects of chemical peeling and the mechanism of wrinkle reduction in photoaged hairless mice skin. After inducing photoaged skin in hairless mice by repetitive ultraviolet-B irradiation applied over 14 weeks, we applied trichloroacetic acid (TCA) 30%, TCA 50%, and phenol on areas of the same size on the backs of the mice. Punch biopsies were obtained 7, 14, 28, and 60 days after the procedure for histologic and immunohistochemical analyses. Histologic examination showed an increase in dermal thickness, collagen fibers, and elastic fibers in the dermis of intervention groups compared with control groups. These increases were maintained significantly for 60 days. This study demonstrates that chemical peeling reduces wrinkles and regenerates skin by increasing dermal thickness and the amount of collagen and elastic fibers in photoaged skin. © 2011 The International Society of Dermatology.

  5. Microwave properties of peeled HEMT devices sapphire substrates

    NASA Technical Reports Server (NTRS)

    Young, Paul G.; Alterovitz, Samuel A.; Mena, Rafael A.; Smith, Edwyn D.

    1992-01-01

    The focus of this research is to demonstrate the first full radio frequency characterization of high electron mobility transistor (HEMT) device parameters. The results of this research are used in the design of circuits with peeled HEMT devices, e.g. 10 GHz amplifiers. Devices were fabricated using two HEMT structures grown by molecular beam epitaxy methods. A 500 A AlAs release layer for 'peel off' was included under the active layers of the structure. The structures are a homogeneously doped Al(0.3)GA(0.7)As/GaAs and a delta doped square well Al(.23)Ga(.77)As/GaAs HEMT structure. Devices were fabricated using a mesa isolation process. Contacts were done by sequentially evaporating Au/Ge/Au/Ni/Au followed by rapid thermal anneal at 400 C for 15 seconds. Gates were wet etch recessed and 1 to 1.4 micron Ti/Au gate metal was deposited. Devices were peeled off the GaAs substrate using Apiezon wax to support the active layer and a HF:DI (1:10) solution to remove the AlAs separation layer. Devices were then attached to sapphire substrates using van der Waals bonding.

  6. Dermal morphological changes following salicylic acid peeling and microdermabrasion.

    PubMed

    Abdel-Motaleb, Amira A; Abu-Dief, Eman E; Hussein, Mahmoud Ra

    2017-12-01

    Microdermabrasion and chemical peeling are popular, inexpensive, and safe methods for treatment of some skin disorders and to rejuvenate skin. To study the alterations of the dermal connective tissue following salicylic acid peeling and microdermabrasion. Twenty patients were participated in our study. All participants underwent facial salicylic acid 30% peel or microdermabrasion (10 cases in each group) weekly for 6 weeks. Punch biopsies were obtained from the clinically normal skin of the right postauricular region 1 week before treatment (control group). Other punch skin biopsies were obtained 1 week after the end of the treatments from the left postauricular area. This region was treated in a similar way to the adjacent lesional skin (treated group). We used routine histological techniques (H&E stain), special stains (Masson trichrome and orcein stains), and image analyzer to study the alterations of the dermal connective tissues. Our study demonstrates variations in the morphological changes between the control and the treated groups, and between chemical peels and microdermabrasion. Both salicylic acid 30% and microdermabrasion were associated with thickened epidermal layer, shallow dermal papillae, dense collagen, and elastic fibers. There was a significant increase among those treated sites vs control regarding epidermal thickness and collagen thickness. Also, there was a highly statistically significant increase among those treated with salicylic acid vs microdermabrasion regarding the epidermal, collagen, and elastin thickness. Both methods stimulate the repair process. The mechanisms underlying these variations are open for further investigations. © 2017 Wiley Periodicals, Inc.

  7. Effect of drying on the bioactive compounds, antioxidant, antibacterial and antityrosinase activities of pomegranate peel.

    PubMed

    Mphahlele, Rebogile R; Fawole, Olaniyi A; Makunga, Nokwanda P; Opara, Umezuruike L

    2016-05-26

    The use of pomegranate peel is highly associated with its rich phenolic concentration. Series of drying methods are recommended since bioactive compounds are highly sensitive to thermal degradation. The study was conducted to evaluate the effects of drying on the bioactive compounds, antioxidant as well as antibacterial and antityrosinase activities of pomegranate peel. Dried pomegranate peels with the initial moisture content of 70.30 % wet basis were prepared by freeze and oven drying at 40, 50 and 60 °C. Difference in CIE-LAB, chroma (C*) and hue angle (h°) were determined using colorimeter. Individual polyphenol retention was determined using LC-MS and LC-MS(E) while total phenolics concentration (TPC), total flavonoid concentration (TFC), total tannins concentration (TTC) and vitamin C concentration were measured using colorimetric methods. The antioxidant activity was measured by radical scavenging activity (RSA) and ferric reducing antioxidant power (FRAP). Furthermore, the antibacterial activity of methanolic peel extracts were tested on Gram negative (Escherichia coli and Klebsiella pneumonia) and Gram positive bacteria (Staphylococcus aureus and Bacillus subtilis) using the in vitro microdilution assays. Tyrosinase enzyme inhibition was investigated against monophenolase (tyrosine) and diphenolase (DOPA), with arbutin as positive controls. Oven drying at 60 °C resulted in high punicalin concentration (888.04 ± 141.03 mg CE/kg dried matter) along with poor red coloration (high hue angle). Freeze dried peel contained higher catechin concentration (674.51 mg/kg drying matter) + catechin and -epicatechin (70.56 mg/kg drying matter) compared to oven dried peel. Furthermore, freeze dried peel had the highest total phenolic, tannin and flavonoid concentrations compared to oven dried peel over the temperature range studied. High concentration of vitamin C (31.19 μg AAE/g dried matter) was observed in the oven dried (40 °C) pomegranate peel

  8. Retrieving quasi-phase-matching structure with discrete layer-peeling method.

    PubMed

    Zhang, Q W; Zeng, X L; Wang, M; Wang, T Y; Chen, X F

    2012-07-02

    An approach to reconstruct a quasi-phase-matching grating by using a discrete layer-peeling algorithm is presented. Experimentally measured output spectra of Šolc-type filters, based on uniform and chirped QPM structures, are used in the discrete layer-peeling algorithm. The reconstructed QPM structures are in agreement with the exact structures used in the experiment and the method is verified to be accurate and efficient in quality inspection on quasi-phase-matching grating.

  9. 20 g PPV with indocyanine green-assisted ILM peeling versus 23 g PPV with brilliant blue G-assisted ILM peeling for epiretinal membrane.

    PubMed

    Manousaridis, Kleanthis; Peter, Silvia; Mennel, Stefan

    2016-06-01

    To compare the anatomical and visual outcomes of 20 gauge (g) pars plana vitrectomy (PPV) with indocyanine green (ICG)-assisted internal limiting membrane (ILM) peeling and 23 g PPV with brilliant blue G (BBG)-assisted ILM peeling for idiopathic epiretinal membrane (ERM). 38 eyes of 38 patients with idiopathic ERM were included. They were divided in two groups: group 1 (18 eyes) underwent 20 g PPV with ICG-assisted ILM peeling and group 2 (20 eyes) 23 g PPV with BBG-assisted ILM peeling. Postoperative best-corrected visual acuity (BCVA) and central macular thickness (CMT) were compared. Average BCVA in group 1 improved significantly from 0.60 logarithm of the minimal angle of resolution (log MAR) at baseline to 0.3 log MAR postoperatively. Average BCVA in group 2 improved significantly from 0.60 log MAR at baseline to 0.3 log MAR postoperatively. Mean CMT reduced significantly from 473 to 375 μm in group 1 and from 486 to 396 μm in group 2. There were no significant differences in the BCVA and CMT between the groups. Both surgical methods appeared to be safe and provided similar anatomical and visual outcomes.

  10. Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris*

    PubMed Central

    Al-Talib, Hassanain; Al-khateeb, Alyaa; Hameed, Ayad; Murugaiah, Chandrika

    2017-01-01

    Acne vulgaris is an extremely common condition affecting the pilosebaceous unit of the skin and characterized by presence of comedones, papules, pustules, nodules, cysts, which might result in permanent scars. Acne vulgaris commonly involve adolescents and young age groups. Active acne vulgaris is usually associated with several complications like hyper or hypopigmentation, scar formation and skin disfigurement. Previous studies have targeted the efficiency and safety of local and systemic agents in the treatment of active acne vulgaris. Superficial chemical peeling is a skin-wounding procedure which might cause some potentially undesirable adverse events. This study was conducted to review the efficacy and safety of superficial chemical peeling in the treatment of active acne vulgaris. It is a structured review of an earlier seven articles meeting the inclusion and exclusion criteria. The clinical assessments were based on pretreatment and post-treatment comparisons and the role of superficial chemical peeling in reduction of papules, pustules and comedones in active acne vulgaris. This study showed that almost all patients tolerated well the chemical peeling procedures despite a mild discomfort, burning, irritation and erythema have been reported; also the incidence of major adverse events was very low and easily manageable. In conclusion, chemical peeling with glycolic acid is a well-tolerated and safe treatment modality in active acne vulgaris while salicylic acid peels is a more convenient for treatment of darker skin patients and it showed significant and earlier improvement than glycolic acid PMID:28538881

  11. Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris.

    PubMed

    Al-Talib, Hassanain; Al-Khateeb, Alyaa; Hameed, Ayad; Murugaiah, Chandrika

    2017-01-01

    Acne vulgaris is an extremely common condition affecting the pilosebaceous unit of the skin and characterized by presence of comedones, papules, pustules, nodules, cysts, which might result in permanent scars. Acne vulgaris commonly involve adolescents and young age groups. Active acne vulgaris is usually associated with several complications like hyper or hypopigmentation, scar formation and skin disfigurement. Previous studies have targeted the efficiency and safety of local and systemic agents in the treatment of active acne vulgaris. Superficial chemical peeling is a skin-wounding procedure which might cause some potentially undesirable adverse events. This study was conducted to review the efficacy and safety of superficial chemical peeling in the treatment of active acne vulgaris. It is a structured review of an earlier seven articles meeting the inclusion and exclusion criteria. The clinical assessments were based on pretreatment and post-treatment comparisons and the role of superficial chemical peeling in reduction of papules, pustules and comedones in active acne vulgaris. This study showed that almost all patients tolerated well the chemical peeling procedures despite a mild discomfort, burning, irritation and erythema have been reported; also the incidence of major adverse events was very low and easily manageable. In conclusion, chemical peeling with glycolic acid is a well-tolerated and safe treatment modality in active acne vulgaris while salicylic acid peels is a more convenient for treatment of darker skin patients and it showed significant and earlier improvement than glycolic acid.

  12. The multiple V-shaped double peeling of elastic thin films from elastic soft substrates

    NASA Astrophysics Data System (ADS)

    Menga, N.; Afferrante, L.; Pugno, N. M.; Carbone, G.

    2018-04-01

    In this paper, a periodic configuration of V-shaped double peeling process is investigated. Specifically, an elastic thin film is detached from a soft elastic material by applying multiple concentrated loads periodically distributed with spatial periodicity λ. The original Kendall's idea is extended to take into account the change in elastic energy occurring in the substrate when the detachment fronts propagate. The symmetric configuration typical of a V-peeling process causes the energy release rate to be sensitive to variations of the elastic energy stored in the soft substrate. This results in an enhancement of the adhesion strength because part of the external work required to trigger the peeling mechanism is converted in substrate elastic energy. A key role is played by both spatial periodicity λ and elasticity ratio E/Eh, between tape and substrate elastic moduli, in determining the conditions of stable adhesion. Indeed, the presence of multiple peeling fronts determines a modification of the mechanism of interaction, because deformations close to each peeling front are also affected by the stresses related to the other fronts. Results show that the energy release rate depends on the detached length of the tape so that conditions can be established which lead to an increase of the supported load compared to the classical peeling on rigid substrates. Finally, we also find that for any given value of the load per unit length, an optimum value of the wavelength λ exists that maximizes the tolerance of the system, before unstable propagation of the peeling front can occur.

  13. Conversion of cassava wastes for biofertilizer production using phosphate solubilizing fungi.

    PubMed

    Ogbo, Frank C

    2010-06-01

    Two fungi characterized as Aspergillus fumigatus and Aspergillus niger, isolated from decaying cassava peels were used to convert cassava wastes by the semi-solid fermentation technique to phosphate biofertilizer. The isolates solubilized Ca(3)(PO(4))(2), AlPO(4) and FePO(4) in liquid Pikovskaya medium, a process that was accompanied by acid production. Medium for the SSF fermentation was composed of 1% raw cassava starch and 3% poultry droppings as nutrients and 96% ground (0.5-1.5mm) dried cassava peels as carrier material. During the 14days fermentation, both test organisms increased in biomass in this medium as indicated by increases in phosphatase activity and drop in pH. Ground cassava peels satisfied many properties required of carrier material particularly in respect of the organisms under study. Biofertilizer produced using A. niger significantly (p<.05) improved the growth of pigeon pea [Cajanus cajan (L.) Millsp.] in pot experiments but product made with A. fumigatus did not. Copyright 2009 Elsevier Ltd. All rights reserved.

  14. Improvement of flavor and viscosity in hot and cold break tomato juice and sauce by peel removal.

    PubMed

    Mirondo, Rita; Barringer, Sheryl

    2015-01-01

    Tomatoes are typically not peeled before being made into juice but the peels contain enzymes that affect the odor, flavor, and viscosity of the juice. The peels are removed in the finisher, but their presence during the break process may affect quality. Juice was processed from peeled and unpeeled tomatoes using hot or cold break. The juices were pasteurized by high temperature short time (HTST), low temperature long time (LTLT), or with a retort. The control samples were treated with 10% calcium chloride to stop enzymatic activity in the juice. Sauce was made from juice and the tomato products were analyzed for volatiles, color, viscosity, and by sensory. Cold break juice made with peel contained higher levels of some lipoxygenase-, carotenoid-, and amino acid-derived volatiles, than the juice made without peel. Because of the lack of enzyme activity, hot break juices had lower levels of these volatiles and there was no significant difference between hot break juices made with and without peel. CaCl2 -treated and HTST juice had higher levels of most of the volatiles than LTLT, including the lipoxygenase-derived volatiles. The presence of peel produced a significant decrease in the viscosity of the cold break juice and sauce. There was no significant difference in the hue angle, total soluble solids, pH, titratable acidity, and vitamin C for most of the treatments. The texture, flavor, and overall liking of cold break juice made without peel were preferred over cold break juice made with peel whereas the color was less preferred. Between the sauces no significant differences in preference were obtained. © 2014 Institute of Food Technologists®

  15. Changes in macular pigment optical density after membrane peeling.

    PubMed

    Romano, Mario R; Cennamo, Gilda; Grassi, Piergiacomo; Sparnelli, Federica; Allegrini, Davide; Cennamo, Giovanni

    2018-01-01

    To highlight the differences in macular pigment optical density (MPOD) between eyes with vitreoretinal interface syndrome and healthy control eyes, to assess the changes in MPOD in eyes treated with macular peeling, to investigate the relationships between MPOD changes and measures of retinal sensitivity such as best corrected visual acuity (BCVA) and microperimetry. In this cross-sectional comparative study, 30 eyes affected by idiopathic epiretinal membrane (iERM, 15eyes) or full-thickness macular hole (FTMH, 15eyes) were compared with 60 eyes from 30 healthy age-matched patients. MPOD values (mean MPOD, maximum MPOD, MPOD area, and MPOD volume) were measured in a range of 4°-7° of eccentricity around the fovea, using the one-wavelength reflectometry method (Visucam 200, Carl-Zeiss Meditec). Patients affected by iERM and FTMH were treated with vitrectomy and epiretinal membrane-inner limiting membrane (ERM-ILM) peeling, with follow-up examinations performed preoperatively and 6 months postoperatively. The main outcome measures were the differences in MPOD between eyes with vitreoretinal interface syndrome and healthy eyes, changes in MPOD after ERM-ILM peeling, and relationships between MPOD and functional changes. Mean MPOD differed significantly between control eyes and those with iERM (P = .0001) or FTMH (P = .0006). The max MPOD and MPOD area increased, but not significantly. After peeling, the only significant change in MPOD was in MPOD volume (P = .01). In the ERM group, postoperative mean MPOD correlated significantly with best-corrected visual acuity (r = .739, P = .002). MPOD was reduced in patients with iERM or FTMH compared with healthy eyes. We found a significant correlation between the mean postoperative MPOD and postoperative BCVA, hypothesizing that the postoperative increase in mean MPOD could be due to a change in distribution for unfolding and expansion of the fovea after the peeling. MOPD may be considered as a prognostic factor associated

  16. Optimal conditions for preparation of banana peels, sugarcane bagasse and watermelon rind in removing copper from water.

    PubMed

    Liu, Cong; Ngo, Huu Hao; Guo, Wenshan; Tung, Kuo-Lun

    2012-09-01

    In this study, three agro-waste materials were used as biosorbents for removal of copper (Cu) from water. This work aims to optimise conditions for preparation of these materials to obtain maximum Cu adsorption capacity. The optimal conditions were determined in terms of Cu removal efficiency and/or energy consumption. The results indicate that banana peels dried at 120°C for 2h and ground into powder form led to a better performance in terms of both copper removal efficiency and energy consumption. For sugarcane bagasse and watermelon rind, 120°C was the suitable drying temperature. However, the best drying time was 1h for sugarcane bagasse and 3h for watermelon rind. The powder form with size of <150 μm was optimal for all biosorbents in terms of removal efficiency and equilibration time. The findings are beneficial to the application of these agro-waste materials for Cu removal from water and wastewater treatment. Copyright © 2012. Published by Elsevier Ltd.

  17. Carbon-Based Fe3O4 Nanocomposites Derived from Waste Pomelo Peels for Magnetic Solid-Phase Extraction of 11 Triazole Fungicides in Fruit Samples

    PubMed Central

    Ren, Keyu; Zhang, Wenlin; Cao, Shurui; Wang, Guomin; Zhou, Zhiqin

    2018-01-01

    Carbon-based Fe3O4 nanocomposites (C/Fe3O4 NCs) were synthesized by a simple one-step hydrothermal method using waste pomelo peels as the carbon precursors. The characterization results showed that they had good structures and physicochemical properties. The prepared C/Fe3O4 NCs could be applied as excellent and recyclable adsorbents for magnetic solid phase extraction (MSPE) of 11 triazole fungicides in fruit samples. In the MSPE procedure, several parameters including the amount of adsorbents, extraction time, the type and volume of desorption solvent, and desorption time were optimized in detail. Under the optimized conditions, the good linearity (R2 > 0.9916), the limits of detection (LOD), and quantification (LOQ) were obtained in the range of 1–100, 0.12–0.55, and 0.39–1.85 μg/kg for 11 pesticides, respectively. Lastly, the proposed MSPE method was successfully applied to analyze triazole fungicides in real apple, pear, orange, peach, and banana samples with recoveries in the range of 82.1% to 109.9% and relative standard deviations (RSDs) below 8.4%. Therefore, the C/Fe3O4 NCs based MSPE method has a great potential for isolating and pre-concentrating trace levels of triazole fungicides in fruits. PMID:29734765

  18. Nutritional Control of Regreening and Degreening in Citrus Peel Segments 1

    PubMed Central

    Huff, Albert

    1983-01-01

    A method for reversibly regreening and degreening citrus epicarp in vitro using peel segments was developed. Peel segments from mature degreened fruit promptly regreened when kept in light upon agar medium containing low (15 millimolar) concentrations of sucrose. Higher concentrations of sucrose inhibited this regreening, but NO3− and certain amino acids included in the media overcame the inhibition by sucrose. However, l-serine strongly inhibited regreening. In the presence of nitrogen, sucrose promoted regreening. Peel segments from green fruit remained green on media with low concentrations of sucrose and on media with high concentrations of sucrose and 60 millimolar KNO3, but degreened in response to high concentrations of sucrose in the absence of nitrogen. Nitrate overcame the degreening effects of high sucrose concentrations in both light and dark. Peel segments were reversibly degreened and regreened by transferring the segments between appropriate media. Nitrate in the media markedly reduced the levels of endogenous sugars in the epicarp and increased endogenous amino acid levels. Sucrose in the media increased endogenous sugar levels and, in the presence of nitrate, increased endogenous amino acid levels. In the absence of nitrogen, high sucrose concentrations reduced endogenous amino acid concentrations. PMID:16663202

  19. Green synthesis of gold nanoparticles using Citrus maxima peel extract and their catalytic/antibacterial activities.

    PubMed

    Yuan, Chun-Gang; Huo, Can; Gui, Bing; Cao, Wei-Ping

    2017-08-01

    The peel of Citrus maxima ( C. maxima ) is the primary byproducts during the process of fruit or juice in food industries, and it was always considered as biomass waste for further treatments. In this study, the authors reported a simple and eco-friendly method to synthesise gold nanoparticles (AuNPs) using C. maxima peel extract as reducing and capping agents. The synthesised AuNPs were characterised by UV-visible spectrum, X-ray diffraction (XRD), transmission electron microscope (TEM) and Fourier-transform infrared spectroscopy (FTIR). The UV-visible spectrum of the AuNPs colloid showed a characteristic peak at 540 nm. The peaks of XRD analysis at (2 θ ) 38.30°, 44.28°, 64.62°, 77.57° and 81.75° were assigned to (111), (200), (220), (311) and (222) planes of the face-centered cubic (fcc) lattice of gold. The TEM images showed that AuNPs were nearly spherical in shape with the size of 8-25 nm. The FTIR spectrum revealed that some bioactive compounds capped the surface of synthesised AuNPs. The biosynthesised AuNPs performed strong catalytic activity in degradation of 4-nitrophenol to 4-aminophenol and good antibacterial activity against both gram negative ( Escherichia coli ) and gram positive ( Staphylococcus aureus ) bacterium. The synthesis procedure was proved simple, cost effective and environment friendly.

  20. The Role of Pectin in Pb Binding by Carrot Peel Biosorbents: Isoterm Adsorption Study

    NASA Astrophysics Data System (ADS)

    Hastuti, B.; Totiana, F.; Winiasih, R.

    2018-04-01

    Cheaply and abundantly biosorption available materials such as carrot peels can be a cost-efficient method for removing heavy metals from wastewater. To investigate the role pectin plays in metal binding by carrot peels, commerce pectin was compared. FTIR spectra confirmed the presence of carboxyl and hydroxyl groups in commerce pectin and carrot pectin. Isoterm experiments showed that all materials could remove Pb (II) ion. All of materials binding Pb (II) follow Freundlich models adsorption. The commerce pectin bindsPb (II) by involving energy 16.6 KJ/mole whereas pectin from carrot peel involves energy 21.09 KJ/mole. It indicates that commerce pectin binds the Pb (II) by physics adsorption whereas pectin from carrot peel by physics and chemical adsorption.

  1. Comparison of alpha- and beta-hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris.

    PubMed

    Kessler, Edward; Flanagan, Katherine; Chia, Christina; Rogers, Cynthia; Glaser, Dee Anna

    2008-01-01

    Chemical peels are used as adjuvants for treatment of facial acne. No well-controlled studies have compared alpha- and beta-hydroxy acid peels in the treatment of mild to moderately severe facial acne. To compare the efficacy of alpha- and beta-hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris. Twenty patients were recruited in this split-face, double-blind, randomized, controlled study. An alpha-hydroxy acid (30% glycolic acid) was applied to one-half of the face and a beta-hydroxy acid peel (30% salicylic acid) was applied contralaterally every 2 weeks for a total of six treatments. A blinded evaluator performed quantitative assessment of papules and pustules. Both chemical peels were significantly effective by the second treatment (p<.05) and there were no significant differences in effectiveness between the two peels. At 2 months posttreatment, the salicylic acid peel had sustained effectiveness. More adverse events were reported with the glycolic acid peel after the initial treatment. The glycolic acid and salicylic acid peels were similarly effective. The salicylic acid peel had sustained effectiveness and fewer side effects. Alpha- and beta-hydroxy acid peels both offer successful adjunctive treatment of facial acne vulgaris.

  2. Sustainability analysis using FORSEE and continuous forest inventory information to compare volume estimation methods for the Valencia coast redwood tract in Santa Cruz County, California

    Treesearch

    Douglas D. Piirto; Mitchell Haydon; Steve Auten; Benjamin Han; Samantha Gill; Wally Mark; Dale Holderman

    2017-01-01

    The 1,295 ha (3,200 ac) Swanton Pacific Ranch (Swanton) and the associated Valencia Tract in Santa Cruz County have been managed by California Polytechnic State University, San Luis Obispo (Cal Poly) since 1987. Swanton’s Valencia Tract is a 239 ha (591 ac) property located north of Watsonville, California. Cal Poly forest managers have conducted two harvest...

  3. Surgical outcomes after epiretinal membrane peeling combined with cataract surgery.

    PubMed

    Yiu, Glenn; Marra, Kyle V; Wagley, Sushant; Krishnan, Sheela; Sandhu, Harpal; Kovacs, Kyle; Kuperwaser, Mark; Arroyo, Jorge G

    2013-09-01

    To compare functional and anatomical outcomes after idiopathic epiretinal membrane (ERM) peeling combined with phacoemulsification and intraocular lens implantation versus ERM peeling alone. A retrospective, non-randomised comparative case series study was conducted of 81 eyes from 79 patients who underwent ERM peeling at the Beth Israel Deaconess Medical Center between 2001 and 2010. Eyes that underwent combined surgery for ERM and cataracts (group 1) were compared with those that had ERM peeling alone (group 2) with respect to best-corrected visual acuity at 6 months and 1 year after surgery, postoperative central macular thickness (CMT) as measured on optical coherence tomography, and rates of complications, including elevated intraocular pressure (IOP), ERM recurrence and need for reoperation. Mean logMAR visual acuity improved significantly in both groups at 6 months (p<0.001) and 1 year (p<0.001) after surgery. There was no statistical difference between the two groups in visual acuity improvement at 6 months (p=0.108) or 1 year (p=0.094). Mean CMT of both groups also significantly decreased after surgery (p=0.002), with no statistical difference in CMT reduction between the two groups, but a trend toward less CMT reduction in group 1 (p=0.061). The rates of complications, including IOP elevation, ERM recurrence and frequency of reoperation, were similar in the two groups, with non-statistical trends toward greater ERM recurrence (p=0.084) and need for reoperation (p=0.096) in those that had combined surgery. Combined surgery for ERMs and cataracts may potentially be as effective as membrane peeling alone with respect to visual and anatomical outcomes. Further studies are necessary to determine if there may be greater ERM recurrence or need for reoperation after combined surgery.

  4. QUANTITATIVE TESTS OF ELMS AS INTERMEDIATE N PEELING-BALLOONING MODES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    LAO, LL; SNYDER, PB; LEONARD, AW

    2002-07-01

    OAK A271 QUANTITATIVE TESTS OF ELMS AS INTERMEDIATE N PEELING-BALLOONING MODES. Two of the major issues crucial for the design of the next generation tokamak burning plasma devices are the predictability of the edge pedestal height and control of the divertor heat load in H-mode configurations. Both of these are strongly impacted by edge localized modes (ELMs) and their size. A working model for ELMs is that they are intermediate toroidal mode number, n {approx} 5-30, peeling-ballooning modes driven by the large edge pedestal pressure gradient P{prime} and the associated large edge bootstrap current density J{sub BS}. the interplay betweenmore » P{prime} and J{sub BS} as a discharge evolves can excite peeling-ballooning modes over a wide spectrum of n. The pedestal current density plays a dual role by stabilizing the high n ballooning modes via opening access to second stability but providing free energy to drive the intermediate n peeling modes. This makes a systematic evaluation of this model particularly challenging. This paper describes recent quantitative tests of this model using experimental data from the DIII-D and the JT-60U tokamaks. These tests are made possible by recent improvements to the ELITE MHD stability code, which allow an efficient evaluation of the unstable peeling-ballooning modes, as well as by improvements to other diagnostic and analysis techniques. Some of the key testable features of this model are: (1) ELMs are triggered when the growth rates of intermediate n MHD modes become significantly large; (2) ELM sizes are related to the radial widths of the unstable modes; (3) the unstable modes have a strong ballooning character localized in the outboard bad curvature region; (4) at high collisionality, ELM size generally becomes smaller because J{sub BS} is reduced.« less

  5. Food waste volume and origin: Case studies in the Finnish food service sector.

    PubMed

    Silvennoinen, Kirsi; Heikkilä, Lotta; Katajajuuri, Juha-Matti; Reinikainen, Anu

    2015-12-01

    We carried out a project to map the volume and composition of food waste in the Finnish food service sector. The amount, type and origin of avoidable food waste were investigated in 51 food service outlets, including schools, day-care centres, workplace canteens, petrol stations, restaurants and diners. Food service outlet personnel kept diaries and weighed the food produced and wasted during a one-week or one-day period. For weighing and sorting, the food waste was divided into two categories: originally edible (OE) food waste was separated from originally inedible (OIE) waste, such as vegetable peelings, bones and coffee grounds. In addition, food waste (OE) was divided into three categories in accordance with its origins: kitchen waste, service waste and customer leftovers. According to the results, about 20% of all food handled and prepared in the sector was wasted. The findings also suggest that the main drivers of wasted food are buffet services and overproduction. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Reduction of salmonella on valencia oranges by cold plasma treatment

    USDA-ARS?s Scientific Manuscript database

    Orange juice has been the source of recurrent food borne illness outbreaks, primarily associated with Salmonella. There is a need for antimicrobial interventions which can effectively eliminate pathogens from fruit surfaces and reduce the risk of cross-contamination during peeling and processing. To...

  7. Gaseous Viscous Peeling of Linearly Elastic Substrates

    NASA Astrophysics Data System (ADS)

    Elbaz, Shai; Jacob, Hila; Gat, Amir

    2017-11-01

    We study pressure-driven propagation of gas into a micron-scale gap between two linearly elastic substrates. Applying the lubrication approximation, the governing nonlinear evolution equation describes the interaction between elasticity and viscosity, as well as weak rarefaction and low-Mach-number compressibility, characteristic to gaseous microflows. Several physical limits allow simplification of the evolution equation and enable solution by self-similarity. During the peeling process the flow-field transitions between the different limits and the respective approximate solutions. The sequence of limits occurring during the propagation dynamics can be related to the thickness of the prewetting layer of the configuration at rest, yielding an approximate description of the entire peeling dynamics. The results are validated by numerical solutions of the evolution equation. Israel Science Foundation 818/13.

  8. Peel effects on phenolic composition, antioxidant activity, and making of pomegranate juice and wine.

    PubMed

    Wasila, Humaira; Li, Xuan; Liu, Linwei; Ahmad, Imran; Ahmad, Sajjad

    2013-08-01

    Pomegranate peel was used in juicing to find out its effects on the juice products' (storable juice and wine) sensory property, polyphenols composition, and antioxidant ability. Macroporous resin was used to purify the polyphenols, and 6 different in vitro assays were used to comprehensively determine the antioxidant activity of each. The results showed that juicing with peel made the juice bitter and astringent, but contributed better sensory quality to wine. Peel contributed higher total polyphenols and flavonoids, but lower anthocyanins to the juice products, and caused the phenolics content to fluctuate more dramatically during making wine than the storable juice. Polyphenols purified from the juice products containing peel showed higher total reducing ability and 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radical elimination abilities, but their clearance activity of hydroxyl radicals was not positive, and their superoxide anion radical elimination ability showed no significant difference when compared to polyphenols purified from juice products without peel. © 2013 Institute of Food Technologists®

  9. The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups.

    PubMed

    Grimes, P E

    1999-01-01

    There is a dearth of published data regarding chemical peels in darker racial-ethnic groups. The purpose of the present investigation was to assess the clinical efficacy and safety of a new superficial salicylic acid peel in individuals of skin types V and VI. Twenty-five patients were included in this pilot investigation. Nine had acne vulgaris, 5 had post-inflammatory hyperpigmentation, 6 had melasma, and 5 had rough, oily skin with enlarged pores. The patients were pre-treated for 2 weeks with hydroquinone 4% prior to undergoing a series of five salicylic acid chemical peels. The concentrations of salicylic acid were 20% and 30%. The peels were performed at 2 week intervals. RESULTS. Moderate to significant improvement was observed in 88% of the patients. Minimal to mild side effects occurred in 16%. The results of this study suggest that superficial salicylic acid peels are both safe and efficacious for treatment of acne vulgaris, oily skin, textural changes, melasma, and post-inflammatory hyperpigmentation in patients with skin types V and VI.

  10. Tolerance and safety of superficial chemical peeling with salicylic acid in various facial dermatoses.

    PubMed

    Bari, Arfan Ul; Iqbal, Zafar; Rahman, Simeen Ber

    2005-01-01

    Chemical peeling is a skin-wounding procedure that may have some potentially undesirable side-effects. The present study is directed towards safety concerns associated with superficial chemical peeling with salicylic acid in various facial dermatoses. The study was a non-comparative and a prospective one. Two hundred and sixty-eight patients of either sex, aged between 10 to 60 years, undergoing superficial chemical peeling for various facial dermatoses (melasma, acne vulgaris, freckles, post-inflammatory scars/pigmentation, actinic keratoses, plane facial warts, etc.) were included in the study. Eight weekly peeling sessions were carried out in each patient. Tolerance to the procedure and any undesirable effects noted during these sessions were recorded. Almost all the patients tolerated the procedure well. Mild discomfort, burning, irritation and erythema were quite common but the incidence of major side-effects was very low and these too, were easily manageable. There was no significant difference in the incidence of side-effects between facial dermatoses (melasma, acne and other pigmentary disorders). Chemical peeling with salicylic acid is a well tolerated and safe treatment modality in many superficial facial dermatoses.

  11. Opportunity for high value-added chemicals from food supply chain wastes.

    PubMed

    Matharu, Avtar S; de Melo, Eduardo M; Houghton, Joseph A

    2016-09-01

    With approximately 1.3 billion tonnes of food wasted per annum, food supply chain wastes (FSCWs) may be viewed as the contemporary Periodic Table of biobased feedstock chemicals (platform molecules) and functional materials. Herein, the global drivers and case for food waste valorisation within the context of global sustainability, sustainable development goals and the bioeconomy are discussed. The emerging potential of high value added chemicals from certain tropical FSCW is considered as these are grown in three major geographical areas: Brazil, India and China, and likely to increase in volume. FSCW in the context of biorefineries is discussed and two case studies are reported, namely: waste potato, and; orange peel waste. Interestingly, both waste feedstocks, like many others, produce proteins and with the global demand for vegetable proteins on the rise then proteins from FSCW may become a dominant area. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. INTERNAL LIMITING MEMBRANE PEELING-DEPENDENT RETINAL STRUCTURAL CHANGES AFTER VITRECTOMY IN RHEGMATOGENOUS RETINAL DETACHMENT.

    PubMed

    Hisatomi, Toshio; Tachibana, Takashi; Notomi, Shoji; Koyanagi, Yoshito; Murakami, Yusuke; Takeda, Atsunobu; Ikeda, Yasuhiro; Yoshida, Shigeo; Enaida, Hiroshi; Murata, Toshinori; Sakamoto, Taiji; Sonoda, Koh-Hei; Ishibashi, Tatsuro

    2018-03-01

    To examine retinal changes after vitrectomy with internal limiting membrane (ILM) peeling, we used 3-dimensional optical coherence tomography (3D-OCT) in rhegmatogenous retinal detachment cases. The 68 eyes from 67 patients with rhegmatogenous retinal detachment were studied, including 35 detached macula cases (51%) and 33 attached macula cases. Internal limiting membrane peeling was performed with fine forceps after brilliant blue G staining. The 3D-OCT images were obtained with volume-rendering technologies from cross-sectional OCT images. The 3D-OCT detected 45 eyes (66%) with ILM peeling-dependent retinal changes, including dissociated optic nerve fiber layer appearance, dimple sign, temporal macular thinning, ILM peeling area thinning, or forceps-related retinal thinning. The ILM peeled area was detectable in only 9 eyes with 3D-OCT, whereas it was undetectable in other 59 eyes. The dissociated optic nerve fiber layer appearance was detected in 8 of the total cases (12%), and dimple signs were observed in 14 cases (21%). Forceps-related thinning was also noted in eight cases (24%) of attached macula cases and in four cases (11%) of detached macula cases. No postoperative macular pucker was noted in the observational period. The 3D-OCT clearly revealed spatial and time-dependent retinal changes after ILM peeling. The changes occurred in 2 months and remained thereafter.

  13. Human Growth Factor Cream and Hyaluronic Acid Serum in Conjunction with Micro Laser Peel

    PubMed Central

    Katz, Bruce E.; Cohen, Joel L.; Biron, Julie

    2010-01-01

    The present study investigated the use of a novel hyaluronic acid serum in combination with a cream comprising a mixture of human growth factors in conjunction with the micro laser peel procedure for skin rejuvenation. After preconditioning the face with the hyaluronic acid serum followed by the cream twice daily for one month, 15 female volunteers between 35 to 65 years of age with demonstrable facial wrinkling received a micro laser peel on the entire face using an erbium-doped yttrium aluminium garnet laser. Immediately following the laser procedure, the subjects applied the test products twice daily until the second laser peel one month later. Immediately following the second procedure, the subjects reapplied the test products for another month. In the large majority of subjects, erythema or edema, crusts or erosions, and transitory stinging or burning sensations after the micro laser peel were minimal or mild when the skin was treated with the serum followed by the cream. The micro laser peel in conjunction with the test products helped to significantly improve hyperpigmentation, wrinkles, and texture as compared to before treatment. This study with the micro laser peel device demonstrated that a novel hyaluronic acid serum combined with the human growth factor cream can be successfully used for skin rejuvenation in conjunction with light-to-medium invasive laser skin treatments. PMID:21203354

  14. SU-F-T-23: Correspondence Factor Correction Coefficient for Commissioning of Leipzig and Valencia Applicators with the Standard Imaging IVB 1000

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Donaghue, J; Gajdos, S

    Purpose: To determine the correction factor of the correspondence factor for the Standard Imaging IVB 1000 well chamber for commissioning of Elekta’s Leipzig and Valencia skin applicators. Methods: The Leipzig and Valencia applicators are designed to treat small skin lesions by collimating irradiation to the treatment area. Published output factors are used to calculate dose rates for clinical treatments. To validate onsite applicators, a correspondence factor (CFrev) is measured and compared to published values. The published CFrev is based on well chamber model SI HDR 1000 Plus. The CFrev is determined by correlating raw values of the source calibration setupmore » (Rcal,raw) and values taken when each applicator is mounted on the same well chamber with an adapter (Rapp,raw). The CFrev is calculated by using the equation CFrev =Rapp,raw/Rcal,raw. The CFrev was measured for each applicator in both the SI HDR 1000 Plus and the SI IVB 1000. A correction factor, CFIVB for the SI IVB 1000 was determined by finding the ratio of CFrev (SI IVB 1000) and CFrev (SI HDR 1000 Plus). Results: The average correction factors at dwell position 1121 were found to be 1.073, 1.039, 1.209, 1.091, and 1.058 for the Valencia V2, Valencia V3, Leipzig H1, Leipzig H2, and Leipzig H3 respectively. There were no significant variations in the correction factor for dwell positions 1119 through 1121. Conclusion: By using the appropriate correction factor, the correspondence factors for the Leipzig and Valencia surface applicators can be validated with the Standard Imaging IVB 1000. This allows users to correlate their measurements with the Standard Imaging IVB 1000 to the published data. The correction factor is included in the equation for the CFrev as follows: CFrev= Rapp,raw/(CFIVB*Rcal,raw). Each individual applicator has its own correction factor, so care must be taken that the appropriate factor is used.« less

  15. Phenolic compound profiles and antioxidant capacity of Persea americana Mill. peels and seeds of two varieties.

    PubMed

    Kosińska, Agnieszka; Karamać, Magdalena; Estrella, Isabel; Hernández, Teresa; Bartolomé, Begoña; Dykes, Gary A

    2012-05-09

    Avocado processing by the food and cosmetic industries yields a considerable amount of phenolic-rich byproduct such as peels and seeds. Utilization of these byproducts would be favorable from an economic point of view. Methanolic (80%) extracts obtained from lyophilized ground peels and seeds of avocado (Persea americana Mill.) of the Hass and Shepard varieties were characterized for their phenolic compound profiles using the HPLC-PAD technique. The structures of the identified compounds were subsequently unambiguously confirmed by ESI-MS. Compositional analysis revealed that the extracts contained four polyphenolic classes: flavanol monomers, proanthocyanidins, hydroxycinnamic acids, and flavonol glycosides. The presence of 3-O-caffeoylquinic acid, 3-O-p-coumaroylquinic acid, and procyanidin A trimers was identified in seeds of both varieties. Intervarietal differences were apparent in the phenolic compound profiles of peels. Peels of the Shepard variety were devoid of (+)-catechin and procyanidin dimers, which were present in the peels of the Hass variety. Peels of both varieties contained 5-O-caffeoylquinic acid and quercetin derivatives. The differences in the phenolic profiles between varietals were also apparent in the different antioxidant activity of the extracts. The peel extracts had a higher total phenolic compound content and antioxidant activity when compared to the seed extracts. The highest TEAC and ORAC values were apparent in peels of the Haas variety in which they amounted to 0.16 and 0.47 mmol Trolox/g DW, respectively. No significant (p > 0.05) differences were apparent between the TEAC values of seeds of the two varieties but the ORAC values differed significantly (p < 0.05). Overall these findings indicate that both the seeds and peel of avocado can be utilized as a functional food ingredient or as an antioxidant additive.

  16. Studies of Carbonization Process on the Production of Durian Peel Biobriquettes with Mixed Biomass Coconut and Palm Shells

    NASA Astrophysics Data System (ADS)

    Sari, Ellyta; Pasymi; Khatab, Umar; Desmiarti, Reni; Ariansyah, Rian; Hariadi; Sutra

    2018-03-01

    Biobriquettes as alternative energy that can replace the role of kerosene. Biobriquettes made from agricultural waste biomass. Biobriquettes durian peel has been researched and developed continuously to obtain optimal quality in terms of calorific value, compressive strength and duration of ignition. In making durian peel biobriquettes needed other biomass mix to sustain duration of Ignition for biobriquettes durian skin quickly burned out. Stages of making biobriquettes durian skin are: material of drying, carbonization of biomass, grinding, mixing with adhesives, and printing. Carbonization process is a process that is important in obtaining the biomass charcoal. Carbonization is done by means of karbonisator pyrolysis. The purpose of this research is to study the process of carbonization to obtain biobriquettes durian skin that of quality in terms of value compressive strength, calorific value, and duration of ignition. Variations that done was kind mix of biomass,coconut shells and palm shells with the massa ratio 2 : 1, type of adhesive used tapioca powder and banana peels, carbonization of temperature 200°C. 300°C and 400 °C. The results showed that the highest compressive strength of the durian skin with a mixture of coconut shell and adhesive tapioca powder and carbonization temperature of 300 °C namely 12,7 g/cm2. The calorific value of the highest on the mix of skin durian with coconut shells and adhesive banana skin with temperature of carbonization 400 °C ie 6040 cal/g, and duration of ignition highest on a mixture of skin durian with coconut shell and adhesive banana skin at a temperature of carbonization 300 °C is 73 minutes.

  17. Photoreceptor change and visual outcome after idiopathic epiretinal membrane removal with or without additional internal limiting membrane peeling.

    PubMed

    Ahn, Seong Joon; Ahn, Jeeyun; Woo, Se Joon; Park, Kyu Hyung

    2014-01-01

    To compare the postoperative photoreceptor status and visual outcome after epiretinal membrane removal with or without additional internal limiting membrane (ILM) peeling. Medical records of 40 eyes from 37 patients undergoing epiretinal membrane removal with residual ILM peeling (additional ILM peeling group) and 69 eyes from 65 patients undergoing epiretinal membrane removal without additional ILM peeling (no additional peeling group) were reviewed. The length of defects in cone outer segment tips, inner segment/outer segment junction, and external limiting membrane line were measured using spectral domain optical coherence tomography images of the fovea before and at 1, 3, 6, and 12 months after the surgery. Cone outer segment tips and inner segment/outer segment junction line defects were most severe at postoperative 1 month and gradually restored at 12 months postoperatively. The cone outer segment tips line defect in the additional ILM peeling group was significantly greater than that in the no additional peeling group at postoperative 1 month (P = 0.006), and best-corrected visual acuity was significantly worse in the former group at the same month (P = 0.001). There was no significant difference in the defect size and best-corrected visual acuity at subsequent visits and recurrence rates between the two groups. Patients who received epiretinal membrane surgery without additional ILM peeling showed better visual and anatomical outcome than those with additional ILM peeling at postoperative 1 month. However, surgical outcomes were comparable between the two groups, thereafter. In terms of visual outcome and photoreceptor integrity, additional ILM peeling may not be an essential procedure.

  18. Use of Banana (Musa acuminata Colla AAA) Peel Extract as an Antioxidant Source in Orange Juices.

    PubMed

    Ortiz, Lucía; Dorta, Eva; Gloria Lobo, M; González-Mendoza, L Antonio; Díaz, Carlos; González, Mónica

    2017-03-01

    Using banana peel extract as an antioxidant in freshly squeezed orange juices and juices from concentrate was evaluated. Free radical scavenging capacity increased by adding banana peel extracts to both types of orange juice. In addition, remarkable increases in antioxidant capacity using 2,2'-azino-bis-(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) radical were observed when equal or greater than 5 mg of banana peel extract per ml of freshly squeezed juice was added. No clear effects were observed in the capacity to inhibit lipid peroxidation. Adding 5 mg banana peel extract per ml of orange juice did not substantially modify the physicochemical and sensory characteristics of either type of juice. However, undesirable changes in the sensory characteristics (in-mouth sensations and colour) were detected when equal or greater than 10 mg banana peel extract per ml of orange juice was added. These results confirm that banana peel is a promising natural additive that increases the capacity to scavenge free radicals of orange juice with acceptable sensory and physicochemical characteristics for the consumer.

  19. The Tethys Rifting of the Valencia Trough Basin

    NASA Astrophysics Data System (ADS)

    Viñas, Marina; Ranero, César R.; Cameselle, Alejandra L.

    2017-04-01

    The western Mediterranean submarine realm is composed of several basin inferred to be formed by a common geodynamic process: upper plate extension during slab rollback of a retreating subduction zone. Although the time evolution of the geometry of the trenches is debated, all models assume that basins opened sequentially from NW (Gulf of Lions) towards the SE (Ligurian-Provençal and later Tyrrhenian basins) and SW (Valencia Trough and later Algerian-South Balearic and Alboran Basin) as trenches migrated. Basin opening history is key to reconstruct kinematics of slab retreat preferred in each model. However, the deep structure of basins is inadequately known due to the paucity of modern wide-angle and multichannel reflection seismic studies across entire systems, and absence of deep drilling in the deep-water regions of the basins, as a result, much of the opening evolution is inferred from indirect evidence. In the Valencia Trough Basin (VTB), drilling and vintage seismic data provide good knowledge of the shallow geology of the basin. However, crustal-scale information across the entire VTB has been limited to two studies (Figure 1): One in the late 80's (Valsis experiment) with three Expanded Spread Profiles that yielded local 1D velocity/depth models used to constrain 2D gravity modeling, and a few multichannel seismic profiles along the Iberian shelf and across segments of the basin. A second study in the early 90's (ESCI experiment) collected a low-resolution deep-penetration multichannel seismic reflection profile across the basin and a coincident wide-angle seismic line with numerous land stations in Iberia but a handful of widely-spaced Ocean Bottom Seismometers. In the absence of modern detailed crustal structure, the origin and evolution of the VTB is still debated. Industry multichannel seismic reflection profiles cover the SW segment of the VTB. This is a region where the basin sea floor is comparatively shallower and has numerous industry wells

  20. Application of edible coating from cassava peel – bay leaf on avocado

    NASA Astrophysics Data System (ADS)

    Handayani, M. N.; Karlina, S.; Sugiarti, Y.; Cakrawati, D.

    2018-05-01

    Avocados have a fairly short shelf life and are included in climacteric fruits. Edible coating application is one alternative to maintain the shelf life of avocado. Cassava peel starch is potential to be used as raw material for edible coating making. Addition of bay leaf extract containing antioxidants can increase the functional value of edible coating. The purpose of this study is to know the shrinkage of weight, acid number, color change and respiration rate of avocado coated with edible coating from cassava peel starch with an addition of bay leaf extract. The study consisted of making cassava peel starch, bay leaf extraction, edible coating making, edible coating application on avocado, and analysis of avocado characteristics during storage at room temperature. The results showed that addition of bay leaf extract on cassava peel starch edible coating applied to avocado, an effect on characteristics of avocado. Avocado applied edible coating and stored at room temperatures had lower weight loss than avocado without edible coating, lower acid number, tend to be more able to maintain color rather than avocado without edible coating.

  1. EFFECT OF INTERNAL LIMITING MEMBRANE PEELING DURING VITRECTOMY FOR DIABETIC MACULAR EDEMA: Systematic Review and Meta-analysis.

    PubMed

    Nakajima, Takuya; Roggia, Murilo F; Noda, Yasuo; Ueta, Takashi

    2015-09-01

    To evaluate the effect of internal limiting membrane (ILM) peeling during vitrectomy for diabetic macular edema. MEDLINE, EMBASE, and CENTRAL were systematically reviewed. Eligible studies included randomized or nonrandomized studies that compared surgical outcomes of vitrectomy with or without ILM peeling for diabetic macular edema. The primary and secondary outcome measures were postoperative best-corrected visual acuity and central macular thickness. Meta-analysis on mean differences between vitrectomy with and without ILM peeling was performed using inverse variance method in random effects. Five studies (7 articles) with 741 patients were eligible for analysis. Superiority (95% confidence interval) in postoperative best-corrected visual acuity in ILM peeling group compared with nonpeeling group was 0.04 (-0.05 to 0.13) logMAR (equivalent to 2.0 ETDRS letters, P = 0.37), and superiority in best-corrected visual acuity change in ILM peeling group was 0.04 (-0.02 to 0.09) logMAR (equivalent to 2.0 ETDRS letters, P = 0.16). There was no significant difference in postoperative central macular thickness and central macular thickness reduction between the two groups. The visual acuity outcomes using pars plana vitrectomy with ILM peeling versus no ILM peeling were not significantly different. A larger randomized prospective study would be necessary to adequately address the effectiveness of ILM peeling on visual acuity outcomes.

  2. Production and Optimization of Physicochemical Parameters of Cellulase Using Untreated Orange Waste by Newly Isolated Emericella variecolor NS3.

    PubMed

    Srivastava, Neha; Srivastava, Manish; Manikanta, Ambepu; Singh, Pardeep; Ramteke, P W; Mishra, P K; Malhotra, Bansi D

    2017-10-01

    Cellulase enzymes have versatile industrial applications. This study was directed towards the isolation, production, and characterization of cellulase enzyme system. Among the five isolated fungal cultures, Emericella variecolor NS3 showed maximum cellulase production using untreated orange peel waste as substrate using solid-state fermentation (SSF). Maximum enzyme production of 31 IU/gds (per gram of dry substrate) was noticed at 6.0 g concentration of orange peel. Further, 50 °C was recorded as the optimum temperature for cellulase activity and the thermal stability for 240 min was observed at this temperature. In addition, the crude enzyme was stable at pH 5.0 and held its complete relative activity in presence of Mn 2+ and Fe 3+ . This study explored the production of crude enzyme system using biological waste with future potential for research and industrial applications.

  3. Exfoliative Skin-peeling, Benefits from This Procedure and Our Experience.

    PubMed

    Grajqevci-Kotori, Merita; Kocinaj, Allma

    2015-12-01

    The peeling procedure is a valuable method for the aged skin, photo aging, acne scars and melasma. It should be performed by dermatologist. Pre peeling preparation of the skin is very important to prepare the skin for this procedure. It can be archived by applying the mask with acids twice a week. The caring of the skin after procedure is also very important for the success of the treatment. Same cases may have complication but managing them is also a challenge for dermatologist.

  4. Leaf photosynthetic and water-relations responses for 'Valencia' orange trees exposed to oxidant air pollution

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olszyk, D.M.; Takemoto, B.K.; Poe, M.

    1991-01-01

    Leaf responses were measured to test a hypothesis that reduced photosynthetic capacity and/or altered water relations were associated with reductions in yield for 'Valencia' orange trees (Citrus sinensis (L.), Osbeck) exposed to ambient oxidant air pollution. Exposures were continuous for 4 years to three levels of oxidants (in charcoal-filtered, half-filtered, and non-filtered air). Oxidants had no effect on net leaf photosynthetic rates or on photosynthetic pigment concentrations. A single set of measurements indicated that oxidants increased leaf starch concentrations (24%) prior to flowering, suggesting a change in photosynthate allocation. Leaves exposed to oxidants had small, but consistent, changes in watermore » relations over the summer growing season, compared to trees growing in filtered air. Other changes included decreased stomatal conductance (12%) and transpiration (9%) rates, and increased water pressure potentials (5%). While all responses were subtle, their cumulative impact over 4 years indicated that 'Valencia' orange trees were subject to increased ambient oxidant stress.« less

  5. Feasibility Study of Using Infrared Radiation Heating as a Sustainable Tomato Peeling Method

    USDA-ARS?s Scientific Manuscript database

    The yye peeling technique is putting both environmental and economic pressure on California tomato processing industry due to its associated salinity issues and wastewater disposal problems. This study is aimed at developing alternative peeling methods with reduced or no caustic usage to produce hi...

  6. Suitable alkaline for graphene peeling grown on metallic catalysts using chemical vapor deposition

    NASA Astrophysics Data System (ADS)

    Karamat, S.; Sonuşen, S.; Çelik, Ü.; Uysallı, Y.; Oral, A.

    2016-04-01

    In chemical vapor deposition, the higher growth temperature roughens the surface of the metal catalyst and a delicate method is necessary for the transfer of graphene from metal catalyst to the desired substrates. In this work, we grow graphene on Pt and Cu foil via ambient pressure chemical vapor deposition (AP-CVD) method and further alkaline water electrolysis was used to peel off graphene from the metallic catalyst. We used different electrolytes i.e., sodium hydroxide (NaOH), potassium hydroxide (KOH), lithium hydroxide (LiOH) and barium hydroxide Ba(OH)2 for electrolysis, hydrogen bubbles evolved at the Pt cathode (graphene/Pt/PMMA stack) and as a result graphene layer peeled off from the substrate without damage. The peeling time for KOH and LiOH was ∼6 min and for NaOH and Ba(OH)2 it was ∼15 min. KOH and LiOH peeled off graphene very efficiently as compared to NaOH and Ba(OH)2 from the Pt electrode. In case of copper, the peeling time is ∼3-5 min. Different characterizations like optical microscopy, Raman spectroscopy, X-ray photoelectron spectroscopy and atomic force microscopy were done to analyze the as grown and transferred graphene samples.

  7. [Drugs use in pregnancy in the Valencia Region and the risk of congenital anomalies].

    PubMed

    Cavero-Carbonell, Clara; Gimeno-Martos, Silvia; Páramo-Rodríguez, Lucía; Rabanaque-Hernández, María José; Martos-Jiménez, Carmen; Zurriaga, Óscar

    2017-09-01

    Despite the potential risks of drug use during pregnancy, consumption has increased in recent decades. To identify the risk of congenital anomalies (CA) associated with the use of drugs in primary care in pregnant women residents in the Valencia Region. A case-control study, considering a case as a less than one year old live birth in 2009-2010, diagnosed with a CA and resident in the Valencia Region, obtained from the CA population-based registry. Controls were selected from the Metabolic Disease Registry, and the drugs prescribed and dispensed from the Integral Management of Pharmaceutical Services. Crude odds ratio (OR) was calculated with its 95% confidence intervals and adjusted OR was calculated using logistic regression. A total of 1,913 cases and 3,826 controls were identified. The most frequently used drug groups were those acting on the musculoskeletal, nervous and respiratory systems, on the blood and blood forming organs, and anti-infection drugs. The most common drugs used were ibuprofen, dexketoprofen, paracetamol, amoxicillin, ferrous sulphate, and a combination of folic acid. A significantly increased risk of CA was identified for drugs acting on the musculoskeletal system (adjusted OR 1.14 [95% confidence interval 1.02-1.28]). A significantly decreased risk was observed for drugs acting on the blood and blood forming organs (adjusted OR 0.87 [95% confidence interval 0.78-0.98]). Associations between drugs and CA in pregnant women resident in the Valencia Region have been identified for drugs that act as risk factors of CA, and for drugs that act as protective factors of CA. Copyright © 2016 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

  8. Antibacterial, antioxidant and tyrosinase-inhibition activities of pomegranate fruit peel methanolic extract

    PubMed Central

    2012-01-01

    Background This study evaluated, using in vitro assays, the antibacterial, antioxidant, and tyrosinase-inhibition activities of methanolic extracts from peels of seven commercially grown pomegranate cultivars. Methods Antibacterial activity was tested on Gram-positive (Bacillus subtilis and Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli and Klebsiella pneumonia) using a microdilution method. Several potential antioxidant activities, including radical-scavenging ability (RSA), ferrous ion chelating (FIC) and ferric ion reducing antioxidant power (FRAP), were evaluated. Tyrosinase enzyme inhibition was investigated against monophenolase (tyrosine) and diphenolase (DOPA), with arbutin and kojic acid as positive controls. Furthermore, phenolic contents including total flavonoid content (TFC), gallotannin content (GTC) and total anthocyanin content (TAC) were determined using colourimetric methods. HPLC-ESI/MSn analysis of phenolic composition of methanolic extracts was also performed. Results Methanolic peel extracts showed strong broad-spectrum activity against Gram-positive and Gram-negative bacteria, with the minimum inhibitory concentrations (MIC) ranging from 0.2 to 0.78 mg/ml. At the highest concentration tested (1000 μg/ml), radical scavenging activities were significantly higher in Arakta (83.54%), Ganesh (83.56%), and Ruby (83.34%) cultivars (P< 0.05). Dose dependent FIC and FRAP activities were exhibited by all the peel extracts. All extracts also exhibited high inhibition (>50%) against monophenolase and diphenolase activities at the highest screening concentration. The most active peel extract was the Bhagwa cultivar against monophenolase and the Arakta cultivar against diphenolase with IC50 values of 3.66 μg/ml and 15.88 μg/ml, respectively. High amounts of phenolic compounds were found in peel extracts with the highest and lowest total phenolic contents of 295.5 (Ganesh) and 179.3 mg/g dry extract (Molla de Elche), respectively

  9. SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVEALS INTERNAL LIMITING MEMBRANE PEELING ALTERS DEEP RETINAL VASCULATURE.

    PubMed

    Michalewska, Zofia; Nawrocki, Jerzy

    2018-04-30

    To describe morphology of retinal and choroidal vessels in swept-source optical coherence tomography angiography before and after vitrectomy with the temporal inverted internal limiting membrane (ILM) flap technique for full-thickness macular holes. Prospective, observational study of 36 eyes of 33 patients with full-thickness macular holes swept-source optical coherence tomography angiography was performed in patients before and 1 month after vitrectomy. Vitrectomy with the temporal inverted ILM flap technique was performed. In this method, ILM is peeled only at one side of the fovea. An ILM flap is created to cover the macular hole. Comparison of retina vasculature in the areas of ILM peeling vs. no ILM peeling at 1 and 3 months after successful vitrectomy was performed. The study demonstrated lower density of vessels in the deep retinal plexus in the area where ILM was peeled as compared to the rest of the fovea. Visual acuity and central retinal thickness 1 month after surgery correlates with fovea avascular zone diameter in deep retinal layers at the same time point (P = 0.001). This study confirmed that ILM peeling might alter blood flow in deep retinal vessels below the peeling area in the early postoperative period. The area of the fovea avascular zone corresponds to functional results at the same time point.

  10. Bio-refinery of orange peels waste: a new concept based on integrated green and solvent free extraction processes using ultrasound and microwave techniques to obtain essential oil, polyphenols and pectin.

    PubMed

    Boukroufa, Meryem; Boutekedjiret, Chahrazed; Petigny, Loïc; Rakotomanomana, Njara; Chemat, Farid

    2015-05-01

    In this study, extraction of essential oil, polyphenols and pectin from orange peel has been optimized using microwave and ultrasound technology without adding any solvent but only "in situ" water which was recycled and used as solvent. The essential oil extraction performed by Microwave Hydrodiffusion and Gravity (MHG) was optimized and compared to steam distillation extraction (SD). No significant changes in yield were noticed: 4.22 ± 0.03% and 4.16 ± 0.05% for MHG and SD, respectively. After extraction of essential oil, residual water of plant obtained after MHG extraction was used as solvent for polyphenols and pectin extraction from MHG residues. Polyphenols extraction was performed by ultrasound-assisted extraction (UAE) and conventional extraction (CE). Response surface methodology (RSM) using central composite designs (CCD) approach was launched to investigate the influence of process variables on the ultrasound-assisted extraction (UAE). The statistical analysis revealed that the optimized conditions of ultrasound power and temperature were 0.956 W/cm(2) and 59.83°C giving a polyphenol yield of 50.02 mgGA/100 g dm. Compared with the conventional extraction (CE), the UAE gave an increase of 30% in TPC yield. Pectin was extracted by conventional and microwave assisted extraction. This technique gives a maximal yield of 24.2% for microwave power of 500 W in only 3 min whereas conventional extraction gives 18.32% in 120 min. Combination of microwave, ultrasound and the recycled "in situ" water of citrus peels allow us to obtain high added values compounds in shorter time and managed to make a closed loop using only natural resources provided by the plant which makes the whole process intensified in term of time and energy saving, cleanliness and reduced waste water. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Impact of chemical peeling combined with negative pressure on human skin.

    PubMed

    Kim, S J; Kang, I J; Shin, M K; Jeong, K H; Baek, J H; Koh, J S; Lee, S J

    2016-10-01

    In vivo changes in skin barrier function after chemical peeling with alpha hydroxyacids (AHAs) have been previously reported. However, the additional effects of physical treatment with chemical agents on skin barrier function have not been adequately studied. This study measured the degree of acute skin damage and the time required for skin barrier repair using non-invasive bioengineering methods in vivo with human skin to investigate the additional effect of a 4% AHA chemical jet accelerated at supersonic velocities. Thirteen female subjects (average age: 29.54 ± 4.86 years) participated in this study. The faces of the subjects were divided into half according to the block randomization design and were then assigned to receive AHA peeling alone or AHA peeling combined with pneumatic pressure on each side of the face. Transepidermal water loss (TEWL), skin colour and skin blood flow were evaluated at baseline and at 30 min, 2, 5 and 7 days after treatment. The TEWL and skin blood flow were significantly increased after 30 min in chemodermabrasion compared with chemical peeling alone (P < 0.05). The TEWL and skin blood flow recovered to baseline after 2 days, and TEWL was significantly decreased at 7 days compared with chemical peeling alone (P < 0.05). Chemodermabrasion can temporarily impair skin barriers, but it is estimated that it can enhance the skin barrier function after 7 days compared to the use of a chemical agent alone. In addition, chemodermabrasion has a more effective impact in the dermis and relatively preserves the skin barrier. © 2016 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

  12. Application of Exogenous Ethylene Inhibits Postharvest Peel Browning of 'Huangguan' Pear.

    PubMed

    Ma, Yurong; Yang, Mengnan; Wang, Jingjing; Jiang, Cai-Zhong; Wang, Qingguo

    2016-01-01

    Peel browning disorder has an enormous impact on the exterior quality of 'Huangguan' pear whereas the underlying mechanism is still unclear. Although different methods have been applied for inhibiting the peel browning of 'Huangguan' pear, there are numerous issues associated with these approaches, such as time cost, efficacy, safety and stability. In this study, to develop a rapid, efficient and safe way to protect 'Huangguan' pear from skin browning, the effect of exogenous ethylene on peel browning of pear fruits stored at 0°C was evaluated. Results showed that ethylene treatments at 0.70-1.28 μL/L significantly decreased the browning rate and browning index from 73.80% and 0.30 to 6.80% and 0.02 after 20 days storage at 0°C, respectively, whereas ethylene treatments at 5 μL/L completely inhibited the occurrence of browning. In addition, ethylene treatments at 5 μL/L decreased the electrolyte leakage and respiration rate, delayed the loss of total phenolic compounds. Furthermore, ethylene (5 μL/L) treatment significantly enhanced the activity of catalase (CAT), ascorbate peroxidase (APX) and superoxide dismutase (SOD) and increased the 1, 1-diphenyl-2-picrylhydrazyl inhibition rate, but inhibited the activity of polyphenol oxidase (PPO) and peroxidase (POD). Our data revealed that ethylene prevented the peel browning through improving antioxidant enzymes (CAT, APX and SOD) activities and reducing PPO activity, electrolyte leakage rate and respiration rate. This study demonstrates that exogenous ethylene application may provide a safe and effective alternative method for controlling browning, and contributes to the understanding of peel browning of 'Huangguan' pear.

  13. Assessment of the effectiveness of orange (Citrus reticulata) peel in the recovery of nickel from electroplating wastewater.

    PubMed

    Hussein, Rim A

    2014-12-01

    Wastewater discharged from electroplating industry contains different concentrations of heavy metals, which when released into the environment pose a health hazard to human beings. The aim of this study was to assess the effectiveness of orange peel as an adsorbent in the recovery of Nickel (Ni) from electroplating wastewater. The effectiveness of orange peel as an adsorbent was assessed by determining the optimum conditions of adsorption (adsorbent dose, pH, and contact time), calculating the recovery percentage, and characterizing the orange peel sludge resulting from adsorption/desorption process as being hazardous or not. Under optimum conditions for adsorption, orange peel was found to be an effective adsorbent of Ni from electroplating wastewater. It achieved 59.28% removal of the metal from a solution containing 528 mg/l, at a dose of 60 g/l, at pH 7, and for 1-h contact time. The nickel uptake capacity of orange peel was calculated to be 5.2 mg/g. Using HCl for desorption of adsorbed Ni, a recovery of 44.46% of Ni discharged in the wastewater could be reached. Orange peel resulting from the adsorption/desorption process was characterized as being nonhazardous. Orange peel was found to be effective in the recovery of nearly half of the amount of Ni discharged in electroplating wastewater. Further studies are required to determine (a) the impact of the recovered NiCl2 solution on the quality of the plated product, (b) the effect of activation of orange peel on the adsorption process, and (c) the number of cycles during which orange peel can be reused as an effective adsorbent.

  14. Exfoliative Skin-peeling, Benefits from This Procedure and Our Experience

    PubMed Central

    Grajqevci-Kotori, Merita; Kocinaj, Allma

    2015-01-01

    The peeling procedure is a valuable method for the aged skin, photo aging, acne scars and melasma. It should be performed by dermatologist. Pre peeling preparation of the skin is very important to prepare the skin for this procedure. It can be archived by applying the mask with acids twice a week. The caring of the skin after procedure is also very important for the success of the treatment. Same cases may have complication but managing them is also a challenge for dermatologist. PMID:26843737

  15. Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris.

    PubMed

    Dayal, Surabhi; Amrani, Ashish; Sahu, Priyadarshini; Jain, Vijay Kumar

    2017-03-01

    Chemical peeling is a well-identified therapeutic modality for acne vulgaris (AV). Jessner's solution (JS) is a known peeling agent for acne since more than 100 years. Salicylic acid (SA) peel is a well-established peeling agent for acne. There is paucity of literature comparing the current peeling agents of choice, that is, SA with the older peeling agents, that is, JS for acne. To compare the efficacy and safety of 30% SA vs. JS peels in treatment of mild-to-moderate facial acne in Indian patients. A total of 40 patients with mild-to-moderate AV were enrolled for 12 weeks and were randomly divided into two groups: group 1, 30% SA peels and group 2, JS peels were performed 2 weeks apart with total of six peels in 12-week duration. Clinical improvement was assessed objectively using Michaelsson acne scores (MAS) and clinical photographs. Side effects were observed at each visit. At the end of therapy, improvement in MAS and percentage decrease in MAS were significantly higher in group 1 as compared to group 2. Likewise, decrease in mean comedone counts in group 1 was significantly higher as compared to group 2. However, there was no statistically significant difference in the decrease in mean papule and pustule counts between the two groups. Both the groups tolerated the peels well. Thus, 30% SA peels were more effective than JS peels in treatment of noninflammatory lesions, that is, comedones and in overall improvement of mild-to-moderate facial acne vulgaris. © 2016 Wiley Periodicals, Inc.

  16. Laccase pretreatment for agrofood wastes valorization.

    PubMed

    Giacobbe, Simona; Pezzella, Cinzia; Lettera, Vincenzo; Sannia, Giovanni; Piscitelli, Alessandra

    2018-06-01

    Apple pomace, potato peels, and coffee silverskin are attractive agrofood wastes for the production of biofuels and chemicals, due to their abundance and carbohydrate content. As lignocellulosic biomasses, their conversion is challenged by the presence of lignin that prevents hydrolysis of polysaccharides, hence demanding a pretreatment step. In this work, the effectiveness of Pleurotus ostreatus laccases (with and without mediator) to remove lignin, improving the subsequent saccharification, was assessed. Optimized conditions for sequential protocol were set up for all agrofood wastes reaching delignification and detoxification yields correlated with high saccharification. Especially noteworthy were results for apple pomace and coffee silverskin for which 83% of and 73% saccharification yields were observed, by using laccase and laccase mediator system, respectively. The herein developed sequential protocol, saving soluble sugars and reducing the amount of wastewater, can improve the overall process for obtaining chemicals or fuels from agrofood wastes. Copyright © 2018 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  17. Apple-peel intestinal atresia: enteroplasty for intestinal lengthening and primary anastomosis.

    PubMed

    Onofre, Luciano Silveira; Maranhão, Renato Frota de Albuquerque; Martins, Elaine Cristina Soares; Fachin, Camila Girardi; Martins, Jose Luiz

    2013-06-01

    Apple-peel atresia (or Type-IIIb intestinal atresia) is an unusual type of jejunoileal atresia. They present with jejunal atresia near the ligament of Treitz and a foreshortened small bowel. Many surgical options have been used, but the optimal method of repair remains unclear. We present a case of a newborn with apple-peel intestinal atresia managed by enteroplasty for intestinal lengthening and primary anastomosis. Copyright © 2013 Elsevier Inc. All rights reserved.

  18. Volatile aroma components and antioxidant activities of the flavedo peel extract of unripe Shiikuwasha (Citrus depressa Hayata).

    PubMed

    Asikin, Yonathan; Taira, Ikuko; Inafuku, Sayuri; Sumi, Hidekazu; Sawamura, Masayoshi; Takara, Kensaku; Wada, Koji

    2012-04-01

    The flavedo peel extracts of unripe Shiikuwasha (Citrus depressa Hayata) fruits were extracted using steam distillation (SD) or a cold-press (CP) system. Volatile aroma content and composition were determined using gas chromatography (GC) and each compound was identified using gas chromatography-mass spectrophotometry (GC-MS). The major constituents of the extracts were monoterpene hydrocarbons (91.75-93.75%[709.32-809.05 mg/100 g of fresh flavedo peel]) including limonene (43.08-45.13%[341.46-379.81 mg/100 g of fresh flavedo peel]), γ-terpinene (27.88-29.06%[219.90-245.86 mg/100 g of fresh flavedo peel]), and p-cymene (8.13-11.02%[61.47-97.22 mg/100 g of fresh flavedo peel]). The extraction process used was determined to be a decisive factor that affects the composition of key citrus aroma components, as well as the antioxidant activities of the Shiikuwasha fruit. Antioxidant capabilities of the extracts were examined by assay of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity and β-carotene bleaching inhibition. The cold-press extraction system may better retain the total phenolic content of the flavedo peel and display superior antioxidant activities, compared to the steam distillation extraction method. Shiikuwasha (Citrus depressa Hayata) is a type of small citrus fruit, and has been used as raw material for beverage and food additive productions in Japan. It had a unique aroma composition in which the limonene content of its peels is lower than that of other commonly known citrus peels. The present study detailed the volatile aroma composition, as well as antioxidant capabilities of Shiikuwasha peel extracts of different extraction methods, that are cold-press and steam distillation methods. The results of this study may provide a basis for selection of Shiikuwasha peel extracts in food industry for citrus flavor production. © 2012 Institute of Food Technologists®

  19. Superficial chemical peeling with salicylic Acid in facial dermatoses.

    PubMed

    Bari, Arfan Ul; Iqbal, Zafar; Rahman, Simeen Ber

    2007-04-01

    To determine the effectiveness of salicylic acid chemical peeling in common dermatological conditions affecting face in people with predominant Fitzpatrick skin type IV and V. An interventional, quasi-experimental study. Military Hospital, Rawalpindi and PAF Hospital, Sargodha, from July 2002 to June 2003. A total of 167 patients of either gender, aged between 13 to 60 years, having some facial dermatoses (melasma, acne vulgaris, postinflammatory hyperpigmentations, freckles, fine lines and wrinkles, post-inflammatory scars, actinic keratoses, and plane facial warts) were included. A series of eight weekly hospital based peeling sessions was conducted in all patients under standardized conditions with 30% salicylic acid. Clinical improvement in different disorders was evaluated by change in MASI score, decrease in the size of affected area and % reduction in lesions count. McNemar test was applied for data analysis. Majority of the patients showed moderate to excellent response. There was 35% to 63% improvement (p<0.05) in all dermatoses. Significant side effects, as feared in Asian skins were not observed. Chemical peeling with salicylic acid is an effective and safe treatment modality in many superficial facial dermatoses.

  20. Effect of cassava peel and cassava bagasse natural fillers on mechanical properties of thermoplastic cassava starch: Comparative study

    NASA Astrophysics Data System (ADS)

    Edhirej, Ahmed; Sapuan, S. M.; Jawaid, Mohammad; Zahari, Nur Ismarrubie; Sanyang, M. L.

    2017-12-01

    Increased awareness of environmental and sustainability issues has generated increased interest in the use of natural fiber reinforced composites. This work focused on the use of cassava roots peel and bagasse as natural fillers of thermoplastic cassava starch (TPS) materials based on cassava starch. The effect of cassava bagasse (CB) and cassava peel (CP) content on the tensile properties of cassava starch (CS) biocomposites films was studied. The biocomposites films were prepared by casting technique using cassava starch (CS) as matrix and fructose as plasticizer. The CB and CP were added to improve the properties of the films. The addition of both fibers increased the tensile strength and modulus while decreased the elongation at break of the biocomposites films. Films containing CB showed higher tensile strength and modulus as compared to the films containing the same amount of CP. The addition of 6 % bagasse increased the modulus and maximum tensile stress to 581.68 and 10.78 MPa, respectively. Thus, CB is considered to be the most efficient reinforcing agent due to its high compatibility with the cassava starch. The use of CB and CP as reinforcement agents for CS thermoplastic cassava added value to these waste by-products and increase the suitability of CS composite films as environmentally friendly food packaging material.

  1. IMPACT OF INTERNAL LIMITING MEMBRANE PEELING ON MACULAR HOLE REOPENING: A Systematic Review and Meta-Analysis.

    PubMed

    Rahimy, Ehsan; McCannel, Colin A

    2016-04-01

    To assess the literature regarding macular hole reopening rates stratified by whether the internal limiting membrane (ILM) was peeled during vitrectomy surgery. Systematic review and meta-analysis of studies reporting on macular hole reopenings among previously surgically closed idiopathic macular holes. A comprehensive literature search using the National Library of Medicine PubMed interface was used to identify potentially eligible publications in English. The minimum mean follow-up period for reports to be included in this study was 12 months. Analysis was divided into eyes that underwent vitrectomy with and without ILM peeling. The primary outcome parameter was the proportion of macular hole reopenings among previously closed holes between the two groups. Secondary outcome parameters included duration from initial surgery to hole reopening and preoperative and postoperative best-corrected correct visual acuities among the non-ILM peeling and ILM peeling groups. A total of 50 publications reporting on 5,480 eyes met inclusion criteria and were assessed in this meta-analysis. The reopening rate without ILM peeling was 7.12% (125 of 1,756 eyes), compared with 1.18% (44 of 3,724 eyes) with ILM peeling (odds ratio: 0.16; 95% confidence interval: 0.11-0.22; Fisher's exact test: P < 0.0001). There were no other identifiable associations or risk factors for reopening. The results of this meta-analysis support the concept that ILM peeling during macular hole surgery reduces the likelihood of macular hole reopening.

  2. Internal limiting membrane peeling and gas tamponade for myopic foveoschisis: a systematic review and meta-analysis.

    PubMed

    Meng, Bo; Zhao, Lu; Yin, Yi; Li, Hongyang; Wang, Xiaolei; Yang, Xiufen; You, Ran; Wang, Jialin; Zhang, Youjing; Wang, Hui; Du, Ran; Wang, Ningli; Zhan, Siyan; Wang, Yanling

    2017-09-08

    Myopic foveoschisis (MF) is among the leading causes of visual loss in high myopia. However, it remains controversial whether internal limiting membrane (ILM) peeling or gas tamponade is necessary treatment option for MF. PubMed, EMBASE, CBM, CNKI, WANFANG DATA and VIP databases were systematically reviewed. Outcome indicators were myopic foveoschisis resolution rate, visual acuity improvement and postoperative complications. Nine studies that included 239 eyes were selected. The proportion of resolution of foveoschisis was higher in ILM peeling group than non-ILM peeling group (OR = 2.15, 95% CI: 1.06-4.35; P = 0.03). The proportion of postoperative complications was higher in Tamponade group than non-Tamponade group (OR = 10.81, 95% CI: 1.26-93.02; P = 0.03). However, the proportion of visual acuity improvement (OR = 1.63, 95% CI: 0.56-4.80; P = 0.37) between ILM peeling group and non-ILM peeling group and the proportion of resolution of foveoschisis (OR = 1.80, 95% CI: 0.76-4.28; P = 0.18) between Tamponade group and non-Tamponade group were similar. Vitrectomy with internal limiting membrane peeling could contribute to better resolution of myopic foveoschisis than non-peeling, however it does not significantly influence the proportion of visual acuity improvement and postoperative complications. Vitrectomy with gas tamponade is associated with more complications than non-tamponade and does not significantly influence the proportion of visual acuity improvement and resolution of myopic foveoschisis.

  3. Effects of internal limiting membrane peeling during vitrectomy for macula-off primary rhegmatogenous retinal detachment.

    PubMed

    Blanco-Teijeiro, María José; Bande Rodriguez, Manuel; Mansilla Cuñarro, Raquel; Paniagua Fernández, Laura; Ruiz-Oliva Ruiz, Francisco; Piñeiro Ces, Antonio

    2018-03-01

    To determine the effectiveness of internal limiting membrane peeling during vitrectomy for macula-off primary rhegmatogenous retinal detachment in the prevention of postoperative epiretinal membrane formation and achievement of good visual outcomes and to identify preoperative and intraoperative risk factors for epiretinal membrane formation. We retrospectively analyzed data from 62 eyes of 62 consecutive patients with macula-off primary rhegmatogenous retinal detachment who underwent vitrectomy with (n = 30) or without (n = 32) internal limiting membrane peeling between January 2014 and March 2016 and were followed up for at least 12 months. The effects of internal limiting membrane peeling on visual outcomes and postoperative recovery of the macular structure were determined. We subsequently divided patients into an epiretinal membrane group and a non-epiretinal membrane group and assessed the effects of various preoperative and intraoperative factors on postoperative epiretinal membrane formation. Postoperative epiretinal membrane developed in 10 patients in the no internal limiting membrane peeling group and three patients in the internal limiting membrane peeling group. Postoperative visual acuity significantly improved in both groups. Epiretinal membrane formation was found to be correlated with a higher number of retinal breaks. Our results suggest that internal limiting membrane peeling during macula-off primary rhegmatogenous retinal detachment surgery can reduce the occurrence of postoperative epiretinal membrane, is safe, and results in favorable visual outcomes.

  4. [Long-term outcome of vitrectomy combined with internal limiting membrane peeling for idiopathic macular holes].

    PubMed

    Yamamoto, Kaori; Hori, Sadao

    2011-01-01

    To elucidate the long-term outcome of internal limiting membrane (ILM) peeling on visual function during vitrectomy for idiopathic macular holes using scanning laser ophthalmoscope (SLO) microperimetry. Prospective uncontrolled study. We studied 31 eyes (29 patients) with idiopathic macular holes. All patients underwent vitrectomy with ILM peeling. The SLO microperimetry was performed preoperatively, and once a year for 3 years postoperatively to detect scotomas in and around the macular holes, and both within and in close vicinity to the areas of ILM peeling. Closure of macular holes after one surgery was confirmed in all cases except for 2 with second surgery. The visual acuity by logarithmic minimum angle of resolution (logMAR) averaged 0.71 +/- 0.36 before surgery, 0.23 +/- 0.31 one year, 0.14 +/- 0.27 two years and 0.12 +/- 0.26 three years after surgery. There was significant improvement up to 2 years after the surgery. All scotomas detected before surgery in the holes, and 77.4% of those detected around the holes decreased gradually. No scotomas were detected in or around the area of ILM peeling either before or after surgery. ILM peeling in vitrectomy for idiopathic macular holes successfully improved visual acuity and did not influence retinal sensitivity in and around the area of ILM peeling. The scotomas detected in and around the holes before surgery gradually reduced or disappeared.

  5. Transcriptome and Metabolome Analyses Provide Insights into the Occurrence of Peel Roughing Disorder on Satsuma Mandarin (Citrus unshiu Marc.) Fruit

    PubMed Central

    Lu, Xiao-Peng; Li, Fei-Fei; Xiong, Jiang; Cao, Xiong-Jun; Ma, Xiao-Chuan; Zhang, Zi-Mu; Cao, Shang-Yin; Xie, Shen-Xi

    2017-01-01

    Roughing disorder (RD) is a significant quality barrier in citrus fruit, prevalent on easy-peeling mandarins. As RD is not yet well-understood, this study aimed to examine the changes and synergic molecular processes involved in peel RD. Peel with RD was induced by severely defruiting Satsuma mandarin trees. Morphology observations, RNA-sequencing, and targeted and untargeted metabolic analyses were conducted. The results showed that the primary metabolites of sugars, organic acids and amino acids are dramatically changed in RD peel. The RD peel was always characterized by higher magnesium content during development. Comparative transcriptome profiling was performed for CK and RD peels at 30, 80, and 170 days after full bloom (DAFB) which represented fruit at cell division stage, cell enlargement stage and fruit maturity stage, respectively. Physiological and molecular biological evidence suggested that the month after full bloom is a crucial stage for RD initiation. A total of 4,855 differentially expressed genes (DEGs) in RD peel, relative to CK peel were detected at cell division stage, about 2 to 4-fold more than other stages had. Among the differentially expressed transcription factors, the bHLH family were affected most by RD, and six bHLH transcription factors functionally involved in GA metabolism were assessed to associate with RD occurrence. Gene set enrichment analysis suggested that RD significantly altered starch and GA metabolism in peel. Higher starch content and hydrolysed chain status were found in RD peel at cell division stage. RD occurrence on the peel was influenced significantly by GA, especially abundant GA before July. These changes may mean a significant alteration in sink strength of RD peel. The findings of this study provide insights into the emergence, development and molecular mechanisms of RD. PMID:29163622

  6. Effects of infrared radiation heating on peeling performance and quality attributes of clingstone peaches

    USDA-ARS?s Scientific Manuscript database

    Salinity and wastewater disposal problems associated with the conventional wet-lye method for peeling clingstone peaches result in considerable negative environment impacts. This study investigated the efficacy of using infrared (IR) heating as an alternative method for peach peel removal without us...

  7. Citrus peel use is associated with reduced risk of squamous cell carcinoma of the skin.

    PubMed

    Hakim, I A; Harris, R B; Ritenbaugh, C

    2000-01-01

    Limonene has demonstrated efficacy in preclinical models of breast and colon cancers. The principal sources of d-limonene are the oils of orange, grapefruit, and lemon. The present case-control study was designed to determine the usual citrus consumption patterns of an older Southwestern population and to then evaluate how this citrus consumption varied with history of squamous cell carcinoma (SCC) of the skin. In this Arizona population, 64.3% and 74.5% of the respondents reported weekly consumption of citrus fruits and citrus juices, respectively. Orange juice (78.5%), orange (74.3%), and grapefruit (65.3%) were the predominant varieties of citrus consumed. Peel consumption was not uncommon, with 34.7% of all subjects reporting citrus peel use. We found no association between the overall consumption of citrus fruits [odds ratio (OR) = 0.99, 95% confidence interval (CI) = 0.73-1.32] or citrus juices (OR = 0.97, 95% CI = 0.71-1.31) and skin SCC. However, the most striking feature was the protection purported by citrus peel consumption (OR = 0.66, 95% CI = 0.45-0.95). Moreover, there was a dose-response relationship between higher citrus peel in the diet and degree of risk lowering. This is the first study to explore the relationship between citrus peel consumption and human cancers. Our results show that peel consumption, the major source of dietary d-limonene, is not uncommon and may have a potential protective effect in relation to skin SCC. Further studies with large sample sizes are needed to more completely evaluate the interrelationships between peel intake, bioavailability of d-limonene, and other lifestyle factors.

  8. Polymer-based alternative method to extract bromelain from pineapple peel waste.

    PubMed

    Novaes, Letícia Celia de Lencastre; Ebinuma, Valéria de Carvalho Santos; Mazzola, Priscila Gava; Pessoa, Adalberto

    2013-01-01

    Bromelain is a mixture of proteolytic enzymes present in all tissues of the pineapple (Ananas comosus Merr.), and it is known for its clinical therapeutic applications, food processing, and as a dietary supplement. The use of pineapple waste for bromelain extraction is interesting from both an environmental and a commercial point of view, because the protease has relevant clinical potential. We aimed to study the optimization of bromelain extraction from pineapple waste, using the aqueous two-phase system formed by polyethylene glycol (PEG) and poly(acrylic acid). In this work, bromelain partitioned preferentially to the top/PEG-rich phase and, in the best condition, achieved a yield of 335.27% with a purification factor of 25.78. The statistical analysis showed that all variables analyzed were significant to the process. © 2013 International Union of Biochemistry and Molecular Biology, Inc.

  9. A pilot scale electrical infrared dry-peeling system for tomatoes: design and performance evaluation

    USDA-ARS?s Scientific Manuscript database

    A pilot scale infrared dry-peeling system for tomatoes was designed and constructed. The system consisted of three major sections including the IR heating, vacuum, and pinch roller sections. The peeling performance of the system was examined under different operational conditions using tomatoes with...

  10. Influence of chemical peeling on the skin stress response system.

    PubMed

    Kimura, Ayako; Kanazawa, Nobuo; Li, Hong-Jin; Yonei, Nozomi; Yamamoto, Yuki; Furukawa, Fukumi

    2012-07-01

    Skin stress response system (SSRS) involves corticotropin-releasing hormone (CRH) and proopiomelanocortin (POMC)-derived peptides, such as adrenocorticotropic hormone (ACTH), a-melanocyte-stimulating hormone (MSH) and b-endorphin that are locally generated in response to locally provided stressors or proinflammatory cytokines. This system would restrict tissue damage and restore local homoeostasis. Trichloroacetic acid (TCA) is one of the most widely used peeling agents and applied for cosmetic treatment of photodamaged skin. However, the biological mechanism responsible for TCA peeling has yet to be fully determined. While our investigation focused on the inflammation and wound healing pathways, in the recent study, we have examined involvement of the SSRS as the third pathway. Mostly depending on our findings that TCA peeling activates the SSRS by inducing the POMC expression of keratinocytes in the CRH-independent manner, together with the results reported by other researchers, we can say that the biological effect of POMC seems to be responsible for the TCA-induced epidermal SSRS activation. © 2012 John Wiley & Sons A/S.

  11. Joint effects of citrus peel use and black tea intake on the risk of squamous cell carcinoma of the skin

    PubMed Central

    Hakim, Iman A; Harris, Robin B

    2001-01-01

    Background Differences in tea drinking habits and/or citrus peel use are likely to vary by populations and could contribute to the inconsistencies found between studies comparing their consumption and cancer risk. Methods A population-based case-control study was used to evaluate the relationships between citrus peel use and black tea intake and squamous cell carcinoma (SCC) of the skin. Moreover, we assessed the independent and interactive effects of citrus peel and black tea in the development of SCC. Results Hot and iced teas were consumed by 30.7% and 51.8% of the subjects, respectively. Peel consumption was reported by 34.5% of subjects. Controls were more likely than were cases to report citrus peel use (odds ratio (OR) = 0.67) and hot tea intake (OR = 0.79). After adjustment for hot and iced tea intake, the ORs associated with citrus peel use were 0.55 and 0.69, respectively, whereas the corresponding adjusted ORs for hot and iced tea intake after adjustment for citrus peel use were 0.87 and 1.22 respectively. Compared with those who did not consume hot black tea or citrus peel, the adjusted ORs associated with sole consumption of hot black tea or citrus peel were 0.60 and 0.30, respectively. Subjects who reported consumption of both hot black tea and citrus peel had a significant marked decrease (OR= 0.22; 95% CI = 0.10 – 0.51) risk of skin SCC. Conclusion These results indicate that both citrus peel use and strong (hot) black tea have independent potential protective effects in relation to skin SCC. PMID:11527506

  12. Production of ethanol from enzymatically hydrolyzed orange peel by the yeast Saccharomyces cerevisiae

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grohmann, K.; Baldwin, E.A.; Buslig, B.S.

    The authors extended their previous investigations of enzymatic hydrolysis of polysaccharides in orange peel by commercial cellulase and pectinase enzymes to higher, more practical concentrations of orange peel solids. High yields of saccharification could be maintained even at substrate concentrations as high as 22-23%, but the rates of solubilization and saccarification decreased 2-3-fold. They also tested the fermentability of these hydrolysates by the yeast Saccharomyces cerevisiae, which revealed the presence of inhibitory compounds. These compounds could be removed by the filtration of hydrolyzed peel. Successful fermentations of filtered hydrolysates were achieved after pH adjustment with calcium carbonate. 27 refs., 6more » figs., 1 tab.« less

  13. Changes in Retinal Thickness after Vitrectomy for Epiretinal Membrane with and without Internal Limiting Membrane Peeling.

    PubMed

    Obata, Shumpei; Fujikawa, Masato; Iwasaki, Keisuke; Kakinoki, Masashi; Sawada, Osamu; Saishin, Yoshitsugu; Kawamura, Hajime; Ohji, Masahito

    2017-01-01

    To investigate anatomic changes in retinal thickness (RT) and functional changes after vitrectomy for idiopathic epiretinal membranes (ERMs) with and without internal limiting membrane (ILM) peeling. The medical records of 100 eyes of 96 patients with ERM who underwent vitrectomy and ERM removal were reviewed retrospectively. The RT was measured by optical coherence tomography, and the area was divided into 9 sections. The best-corrected visual acuity (BCVA), 9 RT areas, and incidence rates of recurrent ERM were compared between the groups with and without ILM peeling before the operation and 12 months postoperatively. Thirty-nine eyes that underwent vitrectomy with ILM peeling and 61 eyes that underwent vitrectomy without ILM peeling met the inclusion criteria. There were no significant differences between the groups in the BCVA and any of the RTs before the operation and 12 months postoperatively. The ERMs recurred in 8 (20.5%) of 39 eyes and 26 (42.6%) of 61 eyes in the groups with and without ILM peeling, respectively, with a difference that reached significance (p = 0.02) 12 months postoperatively. Vitrectomy for ERM affects the BCVA or the RTs 12 months postoperatively. Additional ILM peeling does not affect them, but it might reduce the ERM recurrence rate. © 2016 S. Karger AG, Basel.

  14. SU-F-T-63: Dosimetric Relevance of the Valencia and Leipzig HDR Applicators Plastic Cap

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Granero, D; Candela-Juan, C; Vijande, J

    Purpose: Utilization of HDR brachytherapy treatment of skin lesions using collimated applicators, such as the Valencia or Leipzig is increasing. These applicators are made of cup-shaped tungsten material in order to focalize the radiation into the lesion and to protect nearby tissues. These applicators have an attachable plastic cap that removes secondary electrons generated in the applicator and flattens the treatment surface. The purpose of this study is to examine the dosimetric impact of this cap, and the effect if the cap is not placed during the HDR fraction delivery. Methods: Monte Carlo simulations have been done using the codemore » Geant4 for the Valencia and Leipzig applicators. Dose rate distributions have been obtained for the applicators with and without the plastic cap. An experimental study using EBT3 radiochromic film has been realized in order to verify the Monte Carlo results. Results: The Monte Carlo simulations show that absorbed dose in the first millimeter of skin can increase up to 180% for the Valencia applicator if the plastic cap is absent and up to 1500% for the Leipzig applicators. At deeper distances the increase of dose is smaller being about 10–15%. Conclusion: Important differences have been found if the plastic cap of the applicators is absent in the treatment producing an overdosage in the skin. The user should have a checklist to remind him check always before HDR fraction delivery to insure the plastic cap is placed on the applicator. This work was supported in part by Generalitat Valenciana under Project PROMETEOII/2013/010, by the Spanish Government under Project No. FIS2013-42156, and by a research agreement with Elekta Brachytherapy, Veenendaal, The Netherlands.« less

  15. Acral peeling skin syndrome associated with a novel CSTA gene mutation.

    PubMed

    Muttardi, K; Nitoiu, D; Kelsell, D P; O'Toole, E A; Batta, K

    2016-06-01

    Acral peeling skin syndrome (APSS) is a rare autosomal recessive condition, characterized by asymptomatic peeling of the skin of the hands and feet, often linked to mutations in the gene TGM5. However, more recently recessive loss of function mutations in CSTA, encoding cystatin A, have been linked with APSS and exfoliative ichthyosis. We describe the clinical features in two sisters with APSS, associated with a novel large homozygous deletion encompassing exon 1 of CSTA. © 2015 British Association of Dermatologists.

  16. Potential of Fruit Wastes as Natural Resources of Bioactive Compounds

    PubMed Central

    Deng, Gui-Fang; Shen, Chen; Xu, Xiang-Rong; Kuang, Ru-Dan; Guo, Ya-Jun; Zeng, Li-Shan; Gao, Li-Li; Lin, Xi; Xie, Jie-Feng; Xia, En-Qin; Li, Sha; Wu, Shan; Chen, Feng; Ling, Wen-Hua; Li, Hua-Bin

    2012-01-01

    Fruit wastes are one of the main sources of municipal waste. In order to explore the potential of fruit wastes as natural resources of bioactive compounds, the antioxidant potency and total phenolic contents (TPC) of lipophilic and hydrophilic components in wastes (peel and seed) of 50 fruits were systematically evaluated. The results showed that different fruit residues had diverse antioxidant potency and the variation was very large. Furthermore, the main bioactive compounds were identified and quantified, and catechin, cyanidin 3-glucoside, epicatechin, galangin, gallic acid, homogentisic acid, kaempferol, and chlorogenic acid were widely found in these residues. Especially, the values of ferric-reducing antioxidant power (FRAP), trolox equivalent antioxidant capacity (TEAC) and TPC in the residues were higher than in pulps. The results showed that fruit residues could be inexpensive and readily available resources of bioactive compounds for use in the food and pharmaceutical industries. PMID:22942704

  17. Potential of fruit wastes as natural resources of bioactive compounds.

    PubMed

    Deng, Gui-Fang; Shen, Chen; Xu, Xiang-Rong; Kuang, Ru-Dan; Guo, Ya-Jun; Zeng, Li-Shan; Gao, Li-Li; Lin, Xi; Xie, Jie-Feng; Xia, En-Qin; Li, Sha; Wu, Shan; Chen, Feng; Ling, Wen-Hua; Li, Hua-Bin

    2012-01-01

    Fruit wastes are one of the main sources of municipal waste. In order to explore the potential of fruit wastes as natural resources of bioactive compounds, the antioxidant potency and total phenolic contents (TPC) of lipophilic and hydrophilic components in wastes (peel and seed) of 50 fruits were systematically evaluated. The results showed that different fruit residues had diverse antioxidant potency and the variation was very large. Furthermore, the main bioactive compounds were identified and quantified, and catechin, cyanidin 3-glucoside, epicatechin, galangin, gallic acid, homogentisic acid, kaempferol, and chlorogenic acid were widely found in these residues. Especially, the values of ferric-reducing antioxidant power (FRAP), trolox equivalent antioxidant capacity (TEAC) and TPC in the residues were higher than in pulps. The results showed that fruit residues could be inexpensive and readily available resources of bioactive compounds for use in the food and pharmaceutical industries.

  18. Performance Evaluation of the Educational Leader (PEEL): Another Breakthrough in Competency Based Educational Administration.

    ERIC Educational Resources Information Center

    Metzger, Christa; Lynch, Steven B.

    1974-01-01

    This paper describes the Performance Evaluation of the Education Leader (PEEL) program, initiated from a study to define the competent school administrator and to develop an instrument to measure administrative competence objectively and accurately. The resulting PEEL materials include the following: (a) "Guidelines for Evaluation: The School…

  19. Internal limiting membrane peeling in macula-off retinal detachment complicated by grade B proliferative vitreoretinopathy.

    PubMed

    Foveau, Pauline; Leroy, Bertrand; Berrod, Jean-Paul; Conart, Jean-Baptiste

    2018-04-02

    To investigate the clinical benefit of internal limiting membrane (ILM) peeling as a surgical adjunct in the repair of primary retinal detachment (RD) complicated by grade B proliferative vitreoretinopathy (PVR). Retrospective, interventional, comparative case series. SETTING: Institutional. 75 consecutive patients who underwent vitrectomy for primary macula off RD complicated by grade B PVR. Patients were divided into an ILM peeling (group P) and a no ILM peeling (group NP). Anatomical success rate, best-corrected visual acuity, and spectral-domain optical coherence tomography (SD-OCT) characteristics were collected at 1 and 6 months. In all, 37 eyes with ILM peeling were included in group P and 38 eyes without ILM peeling were included in group NP. The anatomical success rate after single surgery was higher in group P (89%) than in group NP (66%, p=0.03). Mean final visual acuity was 0.41 ±0.40 logMAR in group P versus 0.43 ±0.22 logMAR in group NP (p=0.82). We found no epiretinal membrane (ERM) formation in group P, whereas five cases of ERM (20%) were detected in group NP (p=0.012). The two groups did not differ in terms of cystoid macular edema occurrence, macular thickness, or photoreceptor damage. ILM peeling during vitrectomy in macula off RD complicated by grade B PVR reduces the need for a second surgery for re-detachment or macular pucker. Copyright © 2018. Published by Elsevier Inc.

  20. Biosynthesis of CdS nanoparticles in banana peel extract.

    PubMed

    Zhou, Guang Ju; Li, Shuo Hao; Zhang, Yu Cang; Fu, Yun Zhi

    2014-06-01

    Cadmium sulfide (CdS) nanoparticles (NPs) were synthesized by using banana peel extract as a convenient, non-toxic, eco-friendly 'green' capping agent. Cadmium nitrate and sodium sulfide are main reagents. A variety of CdS NPs are prepared through changing reaction conditions (banana extracts, the amount of banana peel extract, solution pH, concentration and reactive temperature). The prepared CdS colloid displays strong fluorescence spectrum. X-ray diffraction analysis demonstrates the successful formation of CdS NPs. Fourier transform infra-red (FTIR) spectrogram indicates the involvement of carboxyl, amine and hydroxyl groups in the formation of CdS NPs. Transmission electron microscope (TEM) result reveals that the average size of the NPs is around 1.48 nm.

  1. Tomographic Structural Changes of Retinal Layers after Internal Limiting Membrane Peeling for Macular Hole Surgery.

    PubMed

    Faria, Mun Yueh; Ferreira, Nuno P; Cristóvao, Diana M; Mano, Sofia; Sousa, David Cordeiro; Monteiro-Grillo, Manuel

    2018-01-01

    To highlight tomographic structural changes of retinal layers after internal limiting membrane (ILM) peeling in macular hole surgery. Nonrandomized prospective, interventional study in 38 eyes (34 patients) subjected to pars plana vitrectomy and ILM peeling for idiopathic macular hole. Retinal layers were assessed in nasal and temporal regions before and 6 months after surgery using spectral domain optical coherence tomography. Total retinal thickness increased in the nasal region and decreased in the temporal region. The retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), and inner plexiform layer (IPL) showed thinning on both nasal and temporal sides of the fovea. The thickness of the outer plexiform layer (OPL) increased. The outer nuclear layer (ONL) and outer retinal layers (ORL) increased in thickness after surgery in both nasal and temporal regions. ILM peeling is associated with important alterations in the inner retinal layer architecture, with thinning of the RNFL-GCL-IPL complex and thickening of OPL, ONL, and ORL. These structural alterations can help explain functional outcome and could give indications regarding the extent of ILM peeling, even though peeling seems important for higher rate of hole closure. © 2017 S. Karger AG, Basel.

  2. A novel two-step ultrasound post-assisted lye peeling regime for tomatoes: Reducing pollution while improving product yield and quality.

    PubMed

    Gao, Ruiping; Ye, Fayin; Lu, Zhiqiang; Wang, Jiajia; Li Shen, Xiao; Zhao, Guohua

    2018-07-01

    In this paper, the effects and mechanisms of a novel two-step tomato peeling method, hot lye with a post-assistance of ultrasound, were investigated. The present work aims to improve the environmental friendliness of the conventional hot lye tomato peeling method (10% w/v, 97 °C, 45 s). The results showed that 4% (w/v) lye treatment at 97 °C for 30 s with a post-assistance of a 31.97 W/L ultrasound treatment at 70 °C for 50 s achieved a 100% peelability. In this scenario, the peeling yield and lycopene content in the peeled product were significantly higher than the peeling yield and lycopene content with the conventional hot lye peeling method. The present two-step peeling method was concluded with a mechanism of chemico-mechanical synergism, in which the hot lye functions mainly in a chemical way while the ultrasound is a mechanical process. Especially from the lye side, this work first demonstrated that the lye penetrated across the tomato skin via a pitting model rather than evenly. The findings reported in this paper not only provide a novel tomato peeling method with significant environmental benefits but also discover new clues to the peeling mechanism using hot lye. Copyright © 2018 Elsevier B.V. All rights reserved.

  3. Individual phenolic response and peroxidase activity in peel of differently sun-exposed apples in the period favorable for sunburn occurrence.

    PubMed

    Zupan, Anka; Mikulic-Petkovsek, Maja; Slatnar, Ana; Stampar, Franci; Veberic, Robert

    2014-11-15

    Extreme weather events like high solar radiation can cause stress in apple fruits (Malus domestica Borkh.). The aim of the study was to make a screening of individual phenols and peroxidase activity in apple peel as a response to sunburn and different sun-exposures in the period when weather conditions are suitable for sunburn occurrence. Apple fruits of 'Golden Delicious' and 'Braeburn' were sampled. Fruit temperature and color were measured prior HPLC-MS(2) and peroxidase activity analyses. Sunburned peel was darker and more yellow-red in comparison to healthy peel, which appeared yellow-green. Fruit temperature, total as well as individual flavonols and dihydrochalcones, total hydroxycinnamics and perixodase activity were highest in sunburned peel in comparison with healthy sun-exposed peel, furthermore both were different than shaded sides of both fruits and peel of apples inside the tree crown; moreover in sunburned peel dihydrochalcones were determined for the first time. Chlorogenic acid was up to 2.5 times higher, 3-hydroxy-phloretin-2'-O-xyloglucoside was up to 10 times higher and quercetin-3-galactoside was up to 33 times higher in sunburned peel, comparing to shaded sided peels. Flavanols did not show a distinct pattern. A deeper insight in phenolic response against environmental stress caused by high solar radiation and high air temperatures has been made. Copyright © 2014 Elsevier GmbH. All rights reserved.

  4. Effect of Atmospheric Pressure Plasma Treatment on Surface Characteristics and Adhesive Bond Quality of Peel Ply Prepared Composites

    NASA Astrophysics Data System (ADS)

    Tracey, Ashley C.

    The purpose of this research was to investigate if atmospheric pressure plasma treatment could modify peel ply prepared composite surfaces to create strong adhesive bonds. Two peel ply surface preparation composite systems previously shown to create weak bonds (low fracture energy and adhesion failure) that were potential candidates for plasma treatment were Toray T800/3900-2 carbon fiber reinforced polymer (CFRP) prepared with Precision Fabrics Group, Inc. (PFG) 52006 nylon peel ply and Hexcel T300/F155 CFRP prepared with PFG 60001 polyester peel ply. It was hypothesized that atmospheric pressure plasma treatment could functionalize and/or remove peel ply remnants left on the CFRP surfaces upon peel ply removal. Surface characterization measurements and double cantilever beam (DCB) testing were used to determine the effects of atmospheric pressure plasma treatment on surface characteristics and bond quality of peel ply prepared CFRP composites. Previous research showed that Toray T800/3900-2 carbon fiber reinforced epoxy composites prepared with PFG 52006 peel ply and bonded with Cytec MetlBond 1515-3M structural film adhesive failed in adhesion at low fracture energies when tested in the DCB configuration. Previous research also showed that DCB samples made of Hexcel T300/F155 carbon fiber reinforced epoxy composites prepared with PFG 60001 peel ply and bonded with Henkel Hysol EA 9696 structural film adhesive failed in adhesion at low fracture energies. Recent research suggested that plasma treatment could be able to activate these "un-bondable" surfaces and result in good adhesive bonds. Nylon peel ply prepared 177 °C cure and polyester peel ply prepared 127 °C cure CFRP laminates were treated with atmospheric pressure plasma after peel ply removal prior to bonding. Atmospheric pressure plasma treatment was capable of significantly increasing fracture energies and changing failure modes. For Toray T800/3900-2 laminates prepared with PFG 52006 and bonded with

  5. Application of Exogenous Ethylene Inhibits Postharvest Peel Browning of ‘Huangguan’ Pear

    PubMed Central

    Ma, Yurong; Yang, Mengnan; Wang, Jingjing; Jiang, Cai-Zhong; Wang, Qingguo

    2017-01-01

    Peel browning disorder has an enormous impact on the exterior quality of ‘Huangguan’ pear whereas the underlying mechanism is still unclear. Although different methods have been applied for inhibiting the peel browning of ‘Huangguan’ pear, there are numerous issues associated with these approaches, such as time cost, efficacy, safety and stability. In this study, to develop a rapid, efficient and safe way to protect ‘Huangguan’ pear from skin browning, the effect of exogenous ethylene on peel browning of pear fruits stored at 0°C was evaluated. Results showed that ethylene treatments at 0.70–1.28 μL/L significantly decreased the browning rate and browning index from 73.80% and 0.30 to 6.80% and 0.02 after 20 days storage at 0°C, respectively, whereas ethylene treatments at 5 μL/L completely inhibited the occurrence of browning. In addition, ethylene treatments at 5 μL/L decreased the electrolyte leakage and respiration rate, delayed the loss of total phenolic compounds. Furthermore, ethylene (5 μL/L) treatment significantly enhanced the activity of catalase (CAT), ascorbate peroxidase (APX) and superoxide dismutase (SOD) and increased the 1, 1-diphenyl-2-picrylhydrazyl inhibition rate, but inhibited the activity of polyphenol oxidase (PPO) and peroxidase (POD). Our data revealed that ethylene prevented the peel browning through improving antioxidant enzymes (CAT, APX and SOD) activities and reducing PPO activity, electrolyte leakage rate and respiration rate. This study demonstrates that exogenous ethylene application may provide a safe and effective alternative method for controlling browning, and contributes to the understanding of peel browning of ‘Huangguan’ pear. PMID:28149298

  6. [A preliminary study on bioactivity of orange and tangerine peel extracts against aphis and mites].

    PubMed

    Fan, Y; Ding, Z; Yang, L; Xu, L; Zhang, G; Li, K

    1995-07-01

    An assay was made on the bioactivity of the extracts of tangerine peel from Cinocitrus tangerina, orange peel from Citrus sinensis and mixed tangerine peel from Cinocitrus sp. against aphis Semia phis heraclei, Aphis craccivora, Uroleucon gobonis and Myzus persicae using residual film or topical method, and against mites Tetranychus viennensis and T. trancatus using slide-dip or immersion method. Test results show that these extracts have strong bioactivity against aphids and mites. The corrected mortality regression equations and LC50 (or LD50) of these extracts to pests are presented.

  7. Impacts of fresh lime juice and peel on atherosclerosis progression in an animal model.

    PubMed

    Boshtam, Maryam; Asgary, Sedigheh; Moshtaghian, Jamal; Naderi, Gholamali; Jafari-Dinani, Narges

    2013-11-01

    The main protective role of antioxidants in the progression of atherosclerosis has been shown in some studies. Therefore, this project evaluated the effects of Citrus aurantifolia (Christm) juice and peel on antioxidant activity and atherosclerosis progression in rabbits receiving a hypercholesterolemic diet. Forty white New Zealand male rabbits were randomly allocated to four groups. All groups were on hypercholesterolemic diet for two months. While the first group was considered as the hypercholesterolemic control, groups 2 and 3 (intervention groups) received 5 ml/day lime juice and 1 g/day dried lime peel powder, respectively. Group 4 was fed a normal diet (normal control). Before and after the study, weight was measured and a fasting blood specimen was taken from the rabbits. Serum lipids analyses and antioxidant activity evaluations were then performed. The rabbits' aorta and coronary arteries were separated and the presence of fatty streaks was studied. Comparing to the hypercholesterolemic control group (-25.2 ± 7.0), only the plasma total antioxidant capacity change was significantly more in rabbits supplemented with lime juice (16.3 ± 14.7) and peel (8.6 ± 7.1) (P = 0.008). The presence of fatty streaks in coronary arteries and aorta of the intervention groups [juice (0.2 ± 0.01); peel (0.0 ± 0.00)] was significantly decreased compared to the hypercholesterolemic control group (1.2 ± 0.4) (P < 0.001). Based on our findings, Citrus aurantifolia peel and juice increase plasma antioxidant capacity in rabbits, and can thus prevent or decelerate the process of atherogenesis. However, lime peel is more effective than lime juice.

  8. Thermal stability of liquid antioxidative extracts from pomegranate peel.

    PubMed

    Qu, Wenjuan; Li, Pingping; Hong, Jihua; Liu, Zhiling; Chen, Yufang; Breksa, Andrew P; Pan, Zhongli

    2014-03-30

    Liquid extracts from pomegranate peel have the potential for use as natural antioxidant products. This study investigates the quality changes of liquid extracts before and after thermal treatment during sterilization and storage. Liquid pomegranate peel extracts were prepared, sterilized under ultra-high temperature (UHT) at 121 °C for 10 s and then stored at three temperatures (4, 25 and 37 °C) for up to 180 days. The industrial, color, UV-visible spectrum profile and antioxidant (phenolics) characteristics were measured. Thermal sterilization treatment had no negative effects on the industrial, color, spectral and antioxidant characteristics of the extracts. After 180 days, the extracts stored at 4 °C retained 67% of the initial total soluble phenolic content and 58% of the original scavenging activity. The major antioxidant components in the extracts (stored at 4 °C for 180 days) were gallic acid, punicalagin A, punicalagin B and ellagic acid having concentrations of 19.3, 197.2, 221.1 and 92.4 mg L⁻¹, respectively. The results show that liquid pomegranate peel extracts had acceptable thermal stability after sterilization and storage. The recommended storage condition of this product was low temperature. © 2013 Society of Chemical Industry.

  9. Hybrid Position/Force Control of an Active Handheld Micromanipulator for Membrane Peeling

    PubMed Central

    Wells, Trent S.; Yang, Sungwook; MacLachlan, Robert A.; Lobes, Louis A.; Martel, Joseph N.; Riviere, Cameron N.

    2015-01-01

    Background Peeling procedures in retinal surgery require micron-scale manipulation and control of sub-tactile forces. Methods Hybrid position/force control of an actuated handheld microsurgical instrument is presented as a means for simultaneously improving positioning accuracy and reducing forces to prevent avoidable trauma to tissue. The system response was evaluated, and membrane-peeling trials were performed by four test subjects in both artificial and animal models. Results Maximum force was reduced by 56% in both models as compared to position control. No statistically significant effect on procedure duration was observed. Conclusions A hybrid position/force control system has been implemented that successfully attenuates forces and minimizes unwanted excursions during microsurgical procedures such as membrane peeling. Results also suggest that improvements in safety using this technique may be attained without increasing the duration of the procedure. PMID:25962836

  10. Growth and yield of valencia, spanish, virginia and runner market type peanuts in various row spacings

    USDA-ARS?s Scientific Manuscript database

    Currently, the majority of peanuts grown in New Mexico and West Texas are planted in single rows on beds 36 to 40 inches apart. In 2006-2008, several field studies were conducted with Valencia peanuts comparing single row, twin row, and diamond planting patterns in various populations. The basic c...

  11. In Vogue: How Valencia Community College Used a High-Fashion Marketing Campaign to Sharpen Its Image

    ERIC Educational Resources Information Center

    Campagnuolo, Christian

    2008-01-01

    Not unlike many community colleges across the country, Valencia Community College, located in Orlando, Florida, has been working to better connect with its constituents. In an era in which the Internet is opening new lines of communication between schools and prospective students, more community colleges are tapping into the opportunities inherent…

  12. Antioxidant compounds, antioxidant activity and phenolic content in peel from three tropical fruits from Yucatan, Mexico.

    PubMed

    Moo-Huchin, Víctor M; Moo-Huchin, Mariela I; Estrada-León, Raciel J; Cuevas-Glory, Luis; Estrada-Mota, Iván A; Ortiz-Vázquez, Elizabeth; Betancur-Ancona, David; Sauri-Duch, Enrique

    2015-01-01

    The aim of this study was to determine the antioxidant compounds, antioxidant activity and content of individual phenolic compounds of freeze-dried peel from three tropical fruits grown in Yucatan, México: purple star apple (Chrysophyllum cainito L.), yellow cashew and red cashew (Anacardium occidentale). The freeze-dried peels were good source of antioxidant compounds. ABTS and DPPH values in the peel from each fruit were 3050.95-3322.31 μM Trolox/100g dry weight (DW) or 890.19-970.01 mg of vitamin C/100 g DW, and 1579.04-1680.90 μM Trolox/100 g DW or 340.18-362.18 mg of vitamin C/100 g DW, respectively. Six phenolic compounds were identified in the peel from the tropical fruits studied: ferulic, caffeic, sinapic, gallic, ellagic and myricetin. This study demonstrated that freeze-dried peels from purple star apple, yellow cashew and red cashew, could serve as potential sources of antioxidants for use in food and pharmaceutical industries. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Late Immersion in Perspective: The Peel Study.

    ERIC Educational Resources Information Center

    Lapkin, Sharon; And Others

    1983-01-01

    Presents the 1979 evaluation of the Peel County (Ontario) late immersion French program, in the context of some current issues in second language education in Canada. These include the comparative effectiveness of early and late immersion, the importance of intense exposure, and total accumulated hours of instruction. (Author/AMH)

  14. Chemical Peeling with a Modified Phenol Formula for the Treatment of Facial Freckles on Asian Skin.

    PubMed

    Sun, Hua-Feng; Lu, Hai-Shan; Sun, Le-Qi; Ping, Wei-Dong; Mao, Dong-Sheng; Li, Dan

    2018-04-01

    Chemical peeling is an efficient method for the treatment of pigment disorders. For freckles, medium-depth to deep peeling using a phenol solution is one of the most effective chemical peels, and modifications of facial skin can be observed up to 20 years after peeling. However, applying phenol to the skin may cause serious side effects. Phenol peeling has been rarely used in Asia due to its tendency to cause permanent pigmentary changes and hypertrophic scars. In total, 896 Chinese inpatients with facial freckles were enrolled in this study. The phenol formula was modified with crystalline phenol, dyclonine, camphor, anhydrous alcohol and glycerin and adjusted to a concentration of 73.6-90.0%. The entire peeling treatment was divided into two procedures performed separately on 2 days. All patients exhibited 26% or greater improvement, and 99.66% of patients exhibited 51% or greater improvement (good and excellent). Scarring and systemic complications were not observed in any patient. The modified phenol formula is very effective and safe for the treatment of facial freckles in Asian patients. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

  15. Five-Year Outcomes of Surgically Treated Symptomatic Epiretinal Membranes With and Without Internal Limiting Membrane Peeling.

    PubMed

    Sultan, Harris; Wykoff, Charles C; Shah, Ankoor R

    2018-05-01

    The authors evaluated long-term postoperative visual outcomes and recurrence rates following surgery for symptomatic epiretinal membrane (ERM) ± internal limiting membrane (ILM) peeling. This was a retrospective, consecutive case series of 78 patients undergoing vitrectomy for symptomatic ERM between 1/2010 and 4/2012 with follow-up through at least postoperative year 5 (POY5). Outcomes included visual acuity (VA) (Snellen VA converted to logMAR), central retinal thickness (CRT; μm), and ERM recurrence. Subgroup analysis evaluated outcomes related to ILM peeling. Subgroup analysis based on ILM peeling did not find VA (20/50 [0.430 logMAR ± 0.061 logMAR; mean ± SD] vs. 20/60 [0.518 logMAR ± 0.128 logMAR] for ILM vs. non-ILM peeling respectively; P = .513) nor macular thickness (355 μm ± 13 μm vs. 360 μm ± 42 μm; P = .410) to be significantly different at POY5. Recurrence requiring surgery with and without ILM peeling was not statistically significantly different at POY5 (1.6% and 11.8%; P = .118). Vitrectomy for symptomatic ERM led to improved visual and anatomic outcomes with sustained benefit through 5 years. ILM peeling was was associated with reduced ERM recurrence, but this benefit was not statistically significant at POY5. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:296-302.]. Copyright 2018, SLACK Incorporated.

  16. Smos Land Product Validation Activities at the Valencia Anchor Station

    NASA Astrophysics Data System (ADS)

    Lopez-Baeza, Ernesto

    ABSTRACT Soil moisture is a key parameter controlling the exchanges between the land surface and the atmosphere. In spite of being important for weather and climate modeling, this parameter is not well observed at a global scale. The SMOS (Soil Moisture and Ocean Salinity) Mission was designed by the European Space Agency (ESA) to measure soil moisture over continental surfaces as well as surface salinity over the oceans. Since 2001, the Valencia Anchor Station is currently being prepared for the validation of SMOS land products, namely soil moisture content and vegetation water content. The site has recently been selected by the Mission as a core validation site, mainly due to the reasonable homogeneous characteristics of the area which make it appropriate to undertake the validation of SMOS Level 2 land products during the Mission Commissioning Phase, before attempting more complex areas. Close to SMOS launch, ESA has defined and designed a SMOS V alidation Rehearsal C ampaign P lan which purpose is to repeat the Commissioning Phase execution with all centers, all tools, all participants, all structures, all data available, assuming all tools and structures are ready and trying to produce as close as possible the post-launch conditions. The aim is to test the readiness, the ensemble coordination and the speed of operations, and to avoid as far as possible any unexpected deficiencies of the plan and procedure during the real C ommissioning P hase campaigns. For the rehearsal activity, a control area of 10 x 10 km2 has been chosen at the Valencia Anchor Station study area where a network of ground soil moisture measuring stations is being set up based on the definition of homogeneous physio-hydrological units, attending to climatic, soil type, lithology, geology, elevation, slope and vegetation cover conditions. These stations are linked via a wireless communication system to a master post accessible via internet. The ground soil moisture stations will also be used

  17. The Dynamic Microbiota Profile During Pepper (Piper nigrum L.) Peeling by Solid-State Fermentation.

    PubMed

    Hu, Qisong; Zhang, Jiachao; Xu, Chuanbiao; Li, Congfa; Liu, Sixin

    2017-06-01

    White pepper (Piper nigrum L.), a well-known spice, is the main pepper processing product in Hainan province, China. The solid-state method of fermentation can peel pepper in a highly efficient manner and yield high-quality white pepper. In the present study, we used next-generation sequencing to reveal the dynamic changes in the microbiota during pepper peeling by solid-state fermentation. The results suggested that the inoculated Aspergillus niger was dominant throughout the fermentation stage, with its strains constituting more than 95% of the fungi present; thus, the fungal community structure was relatively stable. The bacterial community structure fluctuated across different fermentation periods; among the bacteria present, Pseudomonas, Tatumella, Pantoea, Acinetobacter, Lactococcus, and Enterobacter accounted for more than 95% of all bacteria. Based on the correlations among the microbial community, we found that Pseudomonas and Acinetobacter were significantly positively related with A. niger, which showed strong synergy with them. In view of the microbial functional gene analysis, we found that these three bacteria and fungi were closely related to the production of pectin esterase (COG4677) and acetyl xylan esterase (COG3458), the key enzymes for pepper peeling. The present research clarifies the solid-state fermentation method of pepper peeling and lays a theoretical foundation to promote the development of the pepper peeling process and the production of high-quality white pepper.

  18. Effect of banana pulp and peel flour on physicochemical properties and in vitro starch digestibility of yellow alkaline noodles.

    PubMed

    Ramli, Saifullah; Alkarkhi, Abbas F M; Shin Yong, Yeoh; Min-Tze, Liong; Easa, Azhar Mat

    2009-01-01

    The present study describes the utilization of banana--Cavendish (Musa acuminata L., cv cavendshii) and Dream (Musa acuminata colla. AAA, cv 'Berangan')--pulp and peel flours as functional ingredients in yellow alkaline noodles. Noodles were prepared by partial substitution of wheat flour with ripe banana pulp or peel flours. In most cases, the starch hydrolysis index, predicted glycaemic index (pGI) and physicochemical properties of cooked noodles were affected by banana flour addition. In general, the pGI values of cooked noodles were in the order; banana peel noodles < banana pulp noodles < control noodles. Since the peel flour was higher in total dietary fibre but lower in resistant starch contents than the pulp flour, the low pGI of banana peel noodles was mainly due to its high dietary fibre content. In conclusion, banana pulp and peel flour could be useful for controlling starch hydrolysis of yellow noodles, even though some physicochemical properties of the noodles were altered.

  19. Effect of substituted gelling agents from pomegranate peel on colour, textural and sensory properties of pomegranate jam.

    PubMed

    Abid, Mouna; Yaich, Héla; Hidouri, Hayfa; Attia, Hamadi; Ayadi, M A

    2018-01-15

    A series of pomegranate jams were prepared from a Tunisian ecotype (Tounsi) with different amounts of sugar (10, 20 and 30%) and low-methoxylated pectin (0.2, 0.7 and 1.2%). The most appreciated formulation was that contaning 30% sugars and 0.2% pectin. Then, commercial pectin was substituted by other gelling agents (pomegranate peel powders dried at 50°C vs lyophilized, pectin and fibre extracted from pomegranate peel) for the preparation of pomegranate peel-based jams. The elaborated jams were evaluated for physichochemical, colour, texture and sensory characteristics. Results revealed that the jam (JPP2) elaborated with 0.2% pectin extracted from pomegranate peel exhibited similar overall acceptability to that prepared with commercial pectin. However, it was more acceptable than other pomegranate peel-based jams, which was related to a better appreciation of sweetness and colour. According to the colour and texture measurements, this sample (JPP2) was more reddish and less firm than other samples. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Loss of corneodesmosin leads to severe skin barrier defect, pruritus, and atopy: unraveling the peeling skin disease.

    PubMed

    Oji, Vinzenz; Eckl, Katja-Martina; Aufenvenne, Karin; Nätebus, Marc; Tarinski, Tatjana; Ackermann, Katharina; Seller, Natalia; Metze, Dieter; Nürnberg, Gudrun; Fölster-Holst, Regina; Schäfer-Korting, Monika; Hausser, Ingrid; Traupe, Heiko; Hennies, Hans Christian

    2010-08-13

    Generalized peeling skin disease is an autosomal-recessive ichthyosiform erythroderma characterized by lifelong patchy peeling of the skin. After genome-wide linkage analysis, we have identified a homozygous nonsense mutation in CDSN in a large consanguineous family with generalized peeling skin, pruritus, and food allergies, which leads to a complete loss of corneodesmosin. In contrast to hypotrichosis simplex, which can be associated with specific dominant CDSN mutations, peeling skin disease is characterized by a complete loss of CDSN expression. The skin phenotype is consistent with a recent murine Cdsn knockout model. Using three-dimensional human skin models, we demonstrate that lack of corneodesmosin causes an epidermal barrier defect supposed to account for the predisposition to atopic diseases, and we confirm the role of corneodesmosin as a decisive epidermal adhesion molecule. Therefore, peeling skin disease will represent a new model disorder for atopic diseases, similarly to Netherton syndrome and ichthyosis vulgaris in the recent past.

  1. Loss of Corneodesmosin Leads to Severe Skin Barrier Defect, Pruritus, and Atopy: Unraveling the Peeling Skin Disease

    PubMed Central

    Oji, Vinzenz; Eckl, Katja-Martina; Aufenvenne, Karin; Nätebus, Marc; Tarinski, Tatjana; Ackermann, Katharina; Seller, Natalia; Metze, Dieter; Nürnberg, Gudrun; Fölster-Holst, Regina; Schäfer-Korting, Monika; Hausser, Ingrid; Traupe, Heiko; Hennies, Hans Christian

    2010-01-01

    Generalized peeling skin disease is an autosomal-recessive ichthyosiform erythroderma characterized by lifelong patchy peeling of the skin. After genome-wide linkage analysis, we have identified a homozygous nonsense mutation in CDSN in a large consanguineous family with generalized peeling skin, pruritus, and food allergies, which leads to a complete loss of corneodesmosin. In contrast to hypotrichosis simplex, which can be associated with specific dominant CDSN mutations, peeling skin disease is characterized by a complete loss of CDSN expression. The skin phenotype is consistent with a recent murine Cdsn knockout model. Using three-dimensional human skin models, we demonstrate that lack of corneodesmosin causes an epidermal barrier defect supposed to account for the predisposition to atopic diseases, and we confirm the role of corneodesmosin as a decisive epidermal adhesion molecule. Therefore, peeling skin disease will represent a new model disorder for atopic diseases, similarly to Netherton syndrome and ichthyosis vulgaris in the recent past. PMID:20691404

  2. Enzymatic hydrolysis of flavonoids and pectic oligosaccharides from bergamot (Citrus bergamia Risso) peel.

    PubMed

    Mandalari, Giuseppina; Bennett, Richard N; Kirby, Andrew R; Lo Curto, Rosario B; Bisignano, Giuseppe; Waldron, Keith W; Faulds, Craig B

    2006-10-18

    Pectinolytic and cellulolytic enzymes (Pectinase 62L, Pectinase 690L, and Cellulase CO13P) were used to evaluate the solubilization of carbohydrates and low molecular weight flavonoids from bergamot peel, a major byproduct of the essential oil industry. The enzymes were characterized for main-chain and side-chain polysaccharide hydrolyzing activities and also against pure samples of various flavonoids previously identified in bergamot peel to determine various glycosidase activities. The addition of Pectinase 62L or 690L alone, or the combination of Pectinase 62L and Cellulase CO13P, was capable of solubilizing between 70 and 80% of the bergamot peel, and up to 90% of the flavonoid glycosides present were cleaved to their aglycones. Cellulase CO13P alone solubilized 62% of the peel but had no deglycosylating effect on the flavonoid glycosides. Over a 24-h time course, a rapid release of cell wall carbohydrates was observed after treatment with Pectinase 62L, with a concurrent gradual hydrolysis of the flavonoid glycosides. Size-exclusion chromatography of the solubilized extract showed that after 24-h incubation, the majority of the solubilized carbohydrates were present as monosaccharides with a smaller proportion of oligosaccharides.

  3. Soil erosion after forest fires in the Valencia region

    NASA Astrophysics Data System (ADS)

    González-Pelayo, Óscar; Keizer, Jan Jacob; Cerdà, Artemi

    2014-05-01

    Soil erosion after forest fire is triggered by the lack of vegetation cover and the degradation of the physical, biological and chemical properties (Martí et al., 2012; Fernández et al., 2012; Guénon, 2013). Valencia region belongs to the west Mediterranean basin ("Csa", Köppen climate classification), with drought summer periods that enhance forest fire risk. The characteristics of the climate, lithology and land use history makes this region more vulnerable to soil erosion. In this area, fire recurrence is being increased since late 50s (Pausas, 2004) and post-fire erosion studies became more popular from 80's until nowadays (Cerdá and Mataix-Solera, 2009). Research in Valencia region has contributed significantly to a better understanding of the effect of spatial and temporal scale on runoff and sediment yield measurements. The main achievements concerns: a) direct measurement of erosion rates under a wide range of methodologies (natural vs simulated rainfall, open vs closed plots); from micro- to meso-plot and catchment scale in single (Rubio et al., 1994; Cerdà et al., 1995; Cerdà 1998a; 1998b; Llovet et al., 1998; Cerdà, 2001; Calvo-Cases et al., 2003; Andreu et al., 2001; Mayor et al., 2007; Cerdà and Doerr, 2008) and multiples fires (Campo et al., 2006; González-Pelayo et al., 2010a). Changes in soil properties (Sanroque et al., 1985; Rubio et al., 1997; Boix-Fayós, 1997; Gimeno-Garcia et al., 2000; Guerrero et al., 2001; Mataix-Solera et al., 2004; González-Pelayo et al., 2006; Arcenegui et al., 2008; Campo et al., 2008; Bodí et al., 2012), in post-fire vegetation patterns (Gimeno-García et al., 2007) and, studies on mitigation strategies (Bautista et al., 1996; Abad et al., 2000). b) Progress to understanding post-fire erosion mechanism and sediment movement (Boix-Fayós et al., 2005) by definition of thresholds for sediment losses; fire severity, slope angle, bedrock, rain characteristics, vegetation pattern and ecosystem resilience (Mayor

  4. Phytochemical screening and in-vitro evaluation of pharmacological activities of peels of Musa sapientum and Carica papaya fruit.

    PubMed

    Siddique, Sarmad; Nawaz, Shamsa; Muhammad, Faqir; Akhtar, Bushra; Aslam, Bilal

    2018-06-01

    Aqueous, absolute and 80% ethanolic extract of fruit peels of Musa sapientum and Carica papaya were investigated for their antibacterial activity, measured by disc diffusion method and antioxidant activity, measured by four different methods. Papaya and banana peels were found to contain terpenoids, tannins, alkaloids, saponins steroid, phenols, fixed oils and fats. 80% ethanolic extract of banana peel was found to contain highest total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activity but in papaya peel, highest TPC and reducing activity was shown by water extract while, TFC and radical scavenging activity was given by 80% ethanolic extract. In banana, water extract showed highest antibacterial activity against tested bacteria while in case of papaya, absolute ethanolic extract showed highest antibacterial activity. The present study revealed that peels of banana and papaya fruits are potentially good source of antioxidant and antibacterial agents.

  5. Preparation and tensile properties of linear low density polyethylene/rambutan peels (Nephelium chryseum Blum.) flour blends

    NASA Astrophysics Data System (ADS)

    Nadhirah, A. Ainatun.; Sam, S. T.; Noriman, N. Z.; Voon, C. H.; Samera, S. S.

    2015-05-01

    The effect of rambutan peels flour (RPF) content on the tensile properties of linear low density polyethylene filled with rambutan peel flour was studied. RPF was melt blended with linear low-density polyethylene (LLDPE). LLDPE/RPF blends were prepared by using internal mixer (brabender) at 160 °C with the flour content ranged from 0 to 15 wt%. The tensile properties were tested by using a universal testing machine (UTM) according to ASTM D638. The highest tensile strength was observed for pure LLDPE while the tensile strength LLDPE/RPF decreased gradually with the addition of rambutan peels flour content from 0% to 15%. Young's modulus of 63 µm to 250 µm rambutan peels blends with LLDPE with the fiber loading of 0 - 15 wt% increased with increasing fiber loading.

  6. Banana peel extract suppressed prostate gland enlargement in testosterone-treated mice.

    PubMed

    Akamine, Kiichiro; Koyama, Tomoyuki; Yazawa, Kazunaga

    2009-09-01

    A methanol extract of banana peel (BPEx, 200 mg/kg, p.o.) significantly suppressed the regrowth of ventral prostates and seminal vesicles induced by testosterone in castrated mice. Further studies in the androgen-responsive LNCaP human prostate cancer cell line showed that BPEx inhibited dose-dependently testosterone-induced cell growth, while the inhibitory activities of BPEx did not appear against dehydrotestosterone-induced cell growth. These results indicate that methanol extract of banana peel can inhibit 5alpha-reductase and might be useful in the treatment of benign prostate hyperplasia.

  7. COMPARATIVE ANALYSIS OF RETINAL REATTACHMENT SURGERY WITH OR WITHOUT INTERNAL LIMITING MEMBRANE PEELING TO PREVENT POSTOPERATIVE MACULAR PUCKER.

    PubMed

    Forlini, Matteo; Date, Purva; Ferrari, Luisa Micelli; Lorusso, Massimo; Lecce, Gabriella; Verdina, Tommaso; Neri, Giovanni; Benatti, Caterina; Rossini, Paolo; Bratu, Adriana; DʼEliseo, Domenico; Ferrari, Tommaso Micelli; Cavallini, Gian Maria

    2017-07-18

    To determine whether internal limiting membrane (ILM) peeling during pars plana vitrectomy for rhegmatogenous retinal detachment reduces the incidence of epiretinal membrane (ERM) formation. In this retrospective study, preoperative, intraoperative, and postoperative data from all eyes undergoing pars plana vitrectomy for rhegmatogenous retinal detachment between January 2007 and December 2013 was analyzed. All cases with at least 1-year of follow-up were included. Data collection included vision, intraoperative complications, occurrence of ERM, and spectral domain optical coherence tomography characteristics. The OCTs were retrieved for all eyes and were graded by a single masked grader. Out of 159 eyes recruited, ILM peeling was done in 78 eyes (49%). Overall occurrence of ERM was 20%. Seven eyes (9%) in ILM peeling group and 25 eyes in the non-ILM peeling group (31%) showed ERM (P = 0.001). Postoperative vision was significantly better in eyes that had ILM peeling (0.48 ± 0.4 logarithm of the minimum angle of resolution [20/63] vs. 0.77 ± 0.6 logarithm of the minimum angle of resolution [20/125], P = 0.003). In multivariable models adjusting for type of tamponade, ILM peeling reduced the likelihood of ERM formation by 75% (P = 0.01). Internal limiting membrane peeling during pars plana vitrectomy for rhegmatogenous retinal detachment significantly reduces ERM formation in the postoperative period and is associated with better visual and anatomical outcomes.

  8. Milk Production, Physiological Condition and Performance of Etawa Crossbreed Goats Feed by Ration Supplemented with Mangosteen Peel Flour

    NASA Astrophysics Data System (ADS)

    Dzarnisa; Rachmadi, D.; Azhar, A.; Fakhrur Riza, R.; Hidayati, A.

    2018-02-01

    Study on the effect of the addition of mangosteen (Garcinia mangostana L.) peel flour on physiological condition and performance of Etawa crossbreed goats was done. This was to grant the use of mangosteen peel flour that rich of antioxidants and has variety good benefits for health as feed additive for cattle. This study used a Complete Randomized Block Design consisting of 4 treatment groups and 4 replications each. Subjects were 16 female Etawa crossbreed goats randomly designed into treatments group based on lactation periods. Subjects were feed with traditional rations (control, A), traditional rations and 2.5% mangosteen peel flour (B), tradition rations and 5% mangosteen peel flour (C), and traditional rations and 7,5 % mangosteen peel flour (D). Data on performance (milk production) and physiological condition (respiratory frequency, rectal temperature, and heart rate) obtained were analyzed using analysis of variance (ANOVA). The results showed that the addition of mangosteen peel flour as food additive in the rations resulted in variations in the milk production, physiological condition (rectal temperature, heart rate and respiration frequency) and performances (daily weigh gain, food consumption, ration conversion and breast volume) of Etawa crossbreed goats, but significant effect was only observed in the respiration frequency. The addition of 2.5% mangosteen peel flour in the ration caused the best, expected effects on milk production physiological condition and performance of Etawa crossbreed goats.

  9. Influence of viscoelastic nature on the intermittent peel-front dynamics of adhesive tape

    NASA Astrophysics Data System (ADS)

    Kumar, Jagadish; Ananthakrishna, G.

    2010-07-01

    We investigate the influence of viscoelastic nature of the adhesive on the intermittent peel front dynamics by extending a recently introduced model for peeling of an adhesive tape. As time and rate-dependent deformation of the adhesives are measured in stationary conditions, a crucial step in incorporating the viscoelastic effects applicable to unstable intermittent peel dynamics is the introduction of a dynamization scheme that eliminates the explicit time dependence in terms of dynamical variables. We find contrasting influences of viscoelastic contribution in different regions of tape mass, roller inertia, and pull velocity. As the model acoustic energy dissipated depends on the nature of the peel front and its dynamical evolution, the combined effect of the roller inertia and pull velocity makes the acoustic energy noisier for small tape mass and low-pull velocity while it is burstlike for low-tape mass, intermediate values of the roller inertia and high-pull velocity. The changes are quantified by calculating the largest Lyapunov exponent and analyzing the statistical distributions of the amplitudes and durations of the model acoustic energy signals. Both single and two stage power-law distributions are observed. Scaling relations between the exponents are derived which show that the exponents corresponding to large values of event sizes and durations are completely determined by those for small values. The scaling relations are found to be satisfied in all cases studied. Interestingly, we find only five types of model acoustic emission signals among multitude of possibilities of the peel front configurations.

  10. DETRIMENTAL EFFECTS OF ACTIVE INTERNAL LIMITING MEMBRANE PEELING DURING EPIRETINAL MEMBRANE SURGERY: Microperimetric Analysis.

    PubMed

    Deltour, Jean-Baptiste; Grimbert, Pierre; Masse, Helene; Lebreton, Olivier; Weber, Michel

    2017-03-01

    The aim of the study was to assess the microperimetric consequences of active internal limiting membrane (ILM) peeling during idiopathic epimacular membrane (IEMM) surgery. This retrospective monocentric study included 32 eyes of 31 consecutive patients who underwent IEMM surgery. Internal limiting membrane integrity was assessed by ILM Blue staining after IEMM removal: peeling was spontaneous (Group S) or active (Group A). Preprocedure and postprocedure (1 and 6 months) examinations were performed using visual acuity determination, spectral domain optical coherence tomography and microperimetry. Twenty-two eyes had an "active ILM peeling" and 10 a "spontaneous ILM peeling." Both groups had comparable and significant improvements in visual acuity 6 months after surgery (+1.82 lines [+9 letters] [Group A] and +1.51 lines [+8 letters] [Group S], P < 0.01) associated with a significant reduction in optical coherence tomography central thickness (-99.9 μm [Group A], P < 0.01 and -62.2 μm [Group S], P = 0.05). Six months after surgery, the microperimetry showed more numerous and deeper microscotomas in the Group A than in the Group S (change in the number of microscotomas: 2.09 vs. -0.10, P = 0.06; change in deficit severity score: 13.18 dB vs. -2 dB, P < 0.01 for Group A and S, respectively). The number of microscotomas and also severity were increased in 63.6% of Group A patients and in only 20% of Group S patients. Microscotomas were most frequently located in IEMM and/or ILM areas. Internal limiting membrane peeling has progressively become generalized in IEMM surgery to reduce recurrences. This additional procedure does not change the postoperative visual acuity but increases the development of deeper microscotomas. The real impact on the quality of vision remains unclear. Active ILM peeling in IEMM surgery may be responsible for visual impairment related to its microtraumatic effects.

  11. Multiple minimally invasive Erbium:YAG laser mini-peels for skin rejuvenation: An objective assessment

    PubMed Central

    El-Domyati, Moetaz; El-Ammawi, Tarek S.; Medhat, Walid; Moawad, Osama; Mahoney, Mỹ G.; Uitto, Jouni

    2012-01-01

    Summary Background As the demand for minimally invasive rejuvenation is increasing, micro-peel resurfacing using Erbium:Yttrium Aluminium Garnet (Er:YAG ) laser 2940 nm has been reported for the treatment of photoaged skin without ablation of the epidermis. However, little is known about the efficacy and underlying histologic changes associated with this type of treatment. Aims The purpose of this study is to evaluate the clinical effect and objectively quantify the histological changes in response to multiple sessions of Er:YAG laser 2940 nm mini-peels. Patients and methods Six female volunteers of Fitzpatrick skin type III-IV and Glogau’s class I-III wrinkles were subjected to six microresurfacing peels at 2-week intervals using Er:YAG 2940 nm laser at sub-ablative fluences of 2 - 3 J/cm2 to treat periorbital rhytides. Quantitative evaluation of collagen types I, III and VII, newly synthesized collagen, total elastin and tropoelastin was performed by histochemistry and immunohistochemistry coupled with computerized morphometric analysis at base line, end of treatment, and three months post treatment. Results Compared to the base line, evaluation of volunteers revealed obvious clinical improvement in response to Er:YAG mini-peels. Collagen types I, III, and VII, as well as newly synthesized collagen, together with tropoelastin showed a statistically significant increase in response to treatment, while the mean level of total elastin was significantly decreased in response to treatment. However, this was followed by regression of improvement at 3 months post treatment, but was still better than baseline. Conclusions The present study revealed that multiple Er:YAG mini-peels is a promising treatment option for photoaging as it reverses the signs of photoaged skin with little downtime and side effects. However, to maintain the short term improvement achieved after treatment, continued Er:YAG 2940 nm laser mini-peels is required. PMID:22672276

  12. HPLC-DAD Phenolic Characterization and Antioxidant Activities of Ripe and Unripe Sweet Orange Peels

    PubMed Central

    Omoba, Olufunmilayo Sade; Obafaye, Rebeccah Olajumoke; Salawu, Sule Ola; Boligon, Aline Augusti; Athayde, Margareth Linde

    2015-01-01

    Phenolic compounds of unripe and ripe sweet orange peels were determined using a high-performance liquid chromatography separation method with diode array detector (HPLC-DAD). The in vitro antioxidant properties and the EC50 (concentration required to obtain a 50% antioxidant effect) values were also determined. The predominant phenolic compounds were quercitrin, rutin, and quercetin with values of 18.77 ± 0.01 mg/mL, 18.65 ± 0.03 mg/mL, and 10.39 ± 0.01 mg/mL respectively in unripe orange peel and 22.61 ± 0.01 mg/mL, 17.93 ± 0.03 mg/mL, and 14.03 ± 0.02 mg/mL respectively in ripe orange peel. The antioxidant properties revealed 2,2′-azino-bis(3-ethyl benzothiazoline-6-sulfonic acid) diammonium salt (ABTS) scavenging ability of both unripe and ripe orange peels respectively as 14.68 ± 0.01 and 16.89 ± 0.02 mmol TEAC/g, the Ferric Reducing Antioxidant Properties (FRAP) as 70.69 ± 0.01 and 91.38 ± 0.01 mg gallic acid equivalents/100g, total phenol content as 5.27 ± 0.03 and 9.40 ± 0.01 mg gallic acid equivalents/g and total flavonoid content as 3.30 ± 0.30 and 4.20 ± 0.02 mg quercetin equivalent/g. The antioxidant assays showed enhanced potency of extract from ripe orange peel with EC50 values of 2.71 ± 0.03 mg/mL for 2,2-diphenyl-1-picrylhydrazyl (DPPH), 0.67 ± 0.03 mg/mL for hydroxyl radicals (OH*), 0.57 ± 0.02 mg/mL for Fe2+ chelation, and 0.63 ± 0.06 mg/mL for malondialdehyde (MDA), and was more potent than unripe orange peel. PMID:26783839

  13. What Did Peel County Do In the Great War?

    ERIC Educational Resources Information Center

    Morton, Desmond

    1987-01-01

    Describes the strengths and weaknesses of the Canadian War effort during World War I. Specifically focuses on Peel County, Ontario and the particular problems its inhabitants experienced during the war. (BSR)

  14. The Minorca Basin: a buffer zone between the Valencia and Liguro-Provençal Basins (NW Mediterranean Sea)

    NASA Astrophysics Data System (ADS)

    Pellen, Romain; Aslanian, Daniel; Rabineau, Marina; Leroux, Estelle; Gorini, Christian; Silenziario, Carmine; Blanpied, Christian; Rubino, Jean-Loup

    2017-04-01

    The present-day compartmented Mediterranean physiography is inherited from the last 250 Ma kinematic plate evolution (Eurasian, Africa, Iberic and Nubia plates) which implied the formation of orogenic chains, polyphased basins, and morphological - geodynamic thresholds. The interactions between these entities are strongly debated in the North-Western Mediterranean area. Several Neogene reconstructions have been proposed for the Valencia basin depending of the basin segmentation where each model imply a different subsidence, sedimentary, and palaeo-environmental evolution. Our study propose a new kinematic model for the Valencia Basin (VB) that encompasses the sedimentary infill, vertical movement and basin segmentation. Detailed analyses of seismic profiles and boreholes in the VB reveal a differentiated basin, the Minorca Basin (MB), lying between the old Mesozoic Valencia Basin sensu strico (VBss) and the young Oligocene Liguro-Provencal Basin (LPB) (Pellen et al., 2016). The relationship between these basins is shown through the correlation of four Miocene-to-present-day megasequences. The Central and North Balearic Fracture Zones (CFZ and NBFZ) that border the MB represent two morphological and geodynamical thresholds that created an accommodation in steps between the three domains. Little to no horizontal Neogene movements have been found for the Ibiza and Majorca Islands and imply a vertical "sag" subsidence. In contrast, the counterclockwise movement of the Corso-Sardinian blocks induced a counterclockwise movement of the Minorca block towards the SE along the CFZ and NBFZ, during the exhumation of lower continental crust in the LPB. The South-Eastward Minorca block translation stops when the first atypical oceanic crust occurs. The influence of the Neogene Betic compressional phase is thus limited to the VBss on the basis of a different MB origin. This new understanding places the AlKaPeCa blocks northeastward of the present-day Alboran Area. Both NW-SE and

  15. Efficacy of vitrectomy with triamcinolone assistance versus internal limiting membrane peeling for highly myopic macular hole retinal detachment.

    PubMed

    Wei, Yong; Wang, Ningli; Zu, Zhongqiao; Bi, Chuncao; Wang, Huaizhou; Chen, Fenghua; Yang, Xingguang

    2013-06-01

    To compare the outcomes of pars plana vitrectomy (PPV) with or without the adjuvant surgical procedures: triamcinolone acetonide (TA) assistance and/or internal limiting membrane (ILM) peeling for the treatment of highly myopic macular hole retinal detachment (MHRD). Case-control study. Pars plana vitrectomy combined with 2 kinds of adjuvant surgical procedures were used on 96 highly myopic eyes with MHRD. These eyes were assigned to 4 groups randomly: Group 1, non-TA-assisted PPV and without ILM peeling; Group 2, non-TA-assisted PPV with ILM peeling; Group 3, TA-assisted PPV and without ILM peeling; Group 4, TA-assisted PPV with ILM peeling. Anatomical reattachment of the retina, macular hole closure, and best-corrected visual acuity were measured. The rates of both retinal reattachment and macular hole closure were higher in Group 2 (84.0 and 44.0%) and Group 3 (80.8 and 46.2%) than Group 1 (73.9 and 17.4%); however, there were no differences between Group 2 and Group 3 (P > 0.05). The rates of macular hole closure were extremely low in Group 1 and also in eyes with extreme long axial lengths (≥29.0 mm), "severe" chorioretinal atrophy, and posterior staphyloma. Pars plana vitrectomy with either TA assistance or ILM peeling was effective for the treatment of highly myopic MHRD. If you peel the ILM, adding TA does not affect closure rates; and if TA is used to visualize the vitreous, ILM peeling may not be necessary in MHRD. There was a lower anatomical success rate in MHRD with extreme long axial lengths, severe chorioretinal atrophy, and posterior staphyloma.

  16. Combined Effect of Kimchi Powder and Onion Peel Extract on Quality Characteristics of Emulsion Sausages Prepared with Irradiated Pork.

    PubMed

    Lee, Soo-Yoen; Kim, Hyun-Wook; Hwang, Ko-Eun; Song, Dong-Heon; Choi, Min-Sung; Ham, Youn-Kyung; Choi, Yun-Sang; Lee, Ju-Woon; Lee, Si-Kyung; Kim, Cheon-Jei

    2015-01-01

    This study was conducted to investigate the effects of kimchi powder and onion peel extract on the quality characteristics of emulsion sausage manufactured with irradiated pork. The emulsion sausages were formulated with 2% kimchi powder and/or 0.05% onion peel extract. The changes in pH value of all treatments were similar, depending on storage periods. The addition of kimchi powder increased the redness and yellowness of the emulsion sausage. The addition of onion peel extract decreased the thiobarbituric acid reactive substances value of the emulsion sausages prepared with irradiated pork. The volatile basic nitrogen value of the emulsion sausage prepared with kimchi powder was the highest, whereas that of the emulsion sausage prepared with onion peel extract was the lowest. The treatment without kimchi powder or onion peel extract and the treatments prepared with onion peel extract showed lower microbial populations than the other treatment. Sensory evaluations indicated that a higher acceptability was attained when kimchi powder was added to the emulsion sausages manufactured with irradiated pork. In conclusion, our results suggest that combined use of kimchi powder and onion peel extract could improve quality characteristics and shelf stability of the emulsion sausage formulated with irradiated pork during chilled storage.

  17. Combined Effect of Kimchi Powder and Onion Peel Extract on Quality Characteristics of Emulsion Sausages Prepared with Irradiated Pork

    PubMed Central

    Choi, Yun-Sang; Lee, Ju-Woon; Lee, Si-Kyung

    2015-01-01

    This study was conducted to investigate the effects of kimchi powder and onion peel extract on the quality characteristics of emulsion sausage manufactured with irradiated pork. The emulsion sausages were formulated with 2% kimchi powder and/or 0.05% onion peel extract. The changes in pH value of all treatments were similar, depending on storage periods. The addition of kimchi powder increased the redness and yellowness of the emulsion sausage. The addition of onion peel extract decreased the thiobarbituric acid reactive substances value of the emulsion sausages prepared with irradiated pork. The volatile basic nitrogen value of the emulsion sausage prepared with kimchi powder was the highest, whereas that of the emulsion sausage prepared with onion peel extract was the lowest. The treatment without kimchi powder or onion peel extract and the treatments prepared with onion peel extract showed lower microbial populations than the other treatment. Sensory evaluations indicated that a higher acceptability was attained when kimchi powder was added to the emulsion sausages manufactured with irradiated pork. In conclusion, our results suggest that combined use of kimchi powder and onion peel extract could improve quality characteristics and shelf stability of the emulsion sausage formulated with irradiated pork during chilled storage. PMID:26761840

  18. Design of gecko-inspired fibrillar surfaces with strong attachment and easy-removal properties: a numerical analysis of peel-zone

    PubMed Central

    Zhou, Ming; Pesika, Noshir; Zeng, Hongbo; Wan, Jin; Zhang, Xiangjun; Meng, Yonggang; Wen, Shizhu; Tian, Yu

    2012-01-01

    Despite successful fabrication of gecko-inspired fibrillar surfaces with strong adhesion forces, how to achieve an easy-removal property becomes a major concern that may restrict the wide applications of these bio-inspired surfaces. Research on how geckos detach rapidly has inspired the design of novel adhesive surfaces with strong and reversible adhesion capabilities, which relies on further fundamental understanding of the peeling mechanisms. Recent studies showed that the peel-zone plays an important role in the peeling off of adhesive tapes or fibrillar surfaces. In this study, a numerical method was developed to evaluate peel-zone deformation and the resulting mechanical behaviour due to the deformations of fibrillar surfaces detaching from a smooth rigid substrate. The effect of the geometrical parameters of pillars and the stiffness of backing layer on the peel-zone and peel strength, and the strong attachment and easy-removal properties have been analysed to establish a design map for bio-inspired fibrillar surfaces, which shows that the optimized strong attachment and easy-removal properties can vary by over three orders of magnitude. The adhesion and peeling design map established provides new insights into the design and development of novel gecko-inspired fibrillar surfaces. PMID:22572030

  19. Application of lemon peel essential oil with edible coating agent to prolong shelf life of tofu and strawberry

    NASA Astrophysics Data System (ADS)

    Rahmawati, Della; Chandra, Mega; Santoso, Stefanus; Puteri, Maria Gunawan

    2017-01-01

    The essential oil of sweet orange, lemon, and key lime peel were analyzed for their antimicrobial activity. The antimicrobial activity of each citrus essential oil with different concentration was assessed using broth macro-dilution against Bacillus sp, Eschericia coli, Rhizopus stolonifer, and Botrytis sp which represented specific spoilage microorganism in tofu and fresh strawberry. Among all the citrus peel essential oils tested, lemon peel essential oil with 0.6% concentration showed significant activity as an antimicrobial agent against Escherichia coli and Bacillus sp. In other hand 1% of lemon peel essential oil is also considered to be the best concentration of inhibiting the Rhizopus Stolonifer and Botrytis sp. Lemon peel essential oil which has the highest antimicrobial activity was combined with two different kind of edible coating agents (cassava starch and sodium alginate) and was applied in both tofu and strawberry to observe whether it had possibility to decrease the degradation rate of tofu and strawberry. The addition of 0.6% and 1% lemon peel essential oil with each of edible coating agents was significantly able to reduce the degradation of tofu and fresh strawberry.

  20. Facile synthesis of luminescent carbon dots from mangosteen peel by pyrolysis method

    NASA Astrophysics Data System (ADS)

    Aji, Mahardika Prasetya; Susanto; Wiguna, Pradita Ajeng; Sulhadi

    2017-06-01

    Carbon dots (C-Dots) from mangosteen peel has been synthesized by pyrolysis method. Synthesis of C-Dots is done using precursor solution which is prepared from extract of mangosteen peel as carbon source and urea as passivation agent. C-Dots is successfully formed with absorbance spectra at wavelength 350-550 nm. Urea affects to the formed C-Dots, while the absorbance and the luminescent spectra are independent toward urea. C-Dots from extract of mangosteen peel has size in range 2-15 nm. The absorbance peaks of C-Dots shows significant wavelength shift at visible region as the increasing of synthesized temperature. Shift of wavelength absorbance indicates the change of electronic transition of C-Dots. Meanwhile, the luminescent of C-Dots can be controlled by synthesized temperature as well. C-Dots luminescent were increasing as higher synthesized temperature. It was shown by the shift of wavelength emission into shorter wavelength, 465 nm at 200 °C, 450 nm at 250 °C, and 423 nm at 300 °C. Synthesized temperature also affects size of C-Dots. It has size 10-15 nm at 200 °C, 7-11 nm at 250 °C and 2-4 nm at 300 °C. In addition, temperature corresponds to the structure of carbon chains and C-N configuration of formed C-Dots from mangosteen peel extract.

  1. Efficacy of vitrectomy and epiretinal membrane peeling in eyes with dry age-related macular degeneration.

    PubMed

    Mason, John O; Patel, Shyam A

    2015-01-01

    To study the efficacy of epiretinal membrane (ERM) peeling in eyes with dry age-related macular degeneration (AMD). We retrospectively analyzed patient charts on 17 eyes (16 patients) that underwent ERM peeling with a concurrent diagnosis of dry AMD. Eyes with concurrent dry AMD and with a good preoperative best-corrected visual acuity (BCVA) (better than or equal to 20/50) had a statistically significant mean BCVA improvement at 6 months after ERM peeling. There was a statistical increase in mean BCVA from 20/95 to 20/56 in dry AMD eyes, and no eyes showed worsening in BCVA at 6 months or at most recent follow-up. Five/seventeen (29.4%) eyes had cataract formation or progression. There were no other complications, reoperations, or reoccurrences. ERM peeling in eyes with dry AMD may show significant improvement, especially in eyes with good preoperative BCVA. The procedure is relatively safe with low complications and reoccurrences.

  2. Peel LTP (Pru p 3)--the major allergen of peach--is methylated. A proteomic study.

    PubMed

    Larocca, Marilena; Martelli, Giuseppe; Grossi, Gerarda; Padula, Maria Carmela; Riccio, Paolo; Rossano, Rocco

    2013-12-01

    Lipid transfer protein (LTP, Pru p 3) is the major allergen of peach (Prunus persica), and is in a greater abundance in the peel than in the pulp of the fruit. Peel LTP is more allergenic than pulp LTP, but it is not clear whether this is due to its specific allergenic properties or to its higher concentration. In this study, we have used a new one-step, rapid procedure for the purification of LTP from peel and pulp of four peach varieties [Gladys (white flesh), California (nectarine yellow flesh), Plusplus (yellow flesh), Red Fair (nectarine yellow flesh)] harvested in a field grown in Southern Italy. Purification was based on miniature reversed-phase chromatography, a procedure suitable for proteomic study. Proteomic analysis of purified LTPs revealed that the amino acid sequence of LTP was identical in all peach genotypes but, for the first time, peel LTP was found to be methylated. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Optimization of antimicrobial activity of flavonoid extracts from pomelo (Citrus grandis) peel as food wrap

    NASA Astrophysics Data System (ADS)

    Sugumaran, Kamaraj; Zakaria, Nur Zatul-'Iffah; Abdullah, Rozaini; Jalani, Nur Syazana; Zati-Hanani, Sharifah; Ibrahim, Roshita; Zakaria, Zarina

    2017-09-01

    This study has been carried out to optimize an antimicrobial activity of flavonoid extract from pomelo peels against Staphyloccus aureus (S. aureus). A comparative analysis of total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activity were done on two parts of peel which are albedo (inner peel) and flavedo (outer peel). Based on the result obtained, flavedo showed higher TPC, TFC and antioxidant activity (304.20 mg /g, 74.30 mg /g and 46.86 % respectively) when compared to albedo (150.98 mg /g, 52.97 mg /g and 24.70 % respectively). The effects of different extract concentration and pH on inhibition zone of S. aureus were optimized using Research Surface Methodology (RSM). The optimal condition of parameters was obtained based on the maximum zone of S. aureus inhibition at extract concentration of 200 mg/mL and pH of 4.8. The antimicrobial film has been developed by using optimal conditions by incorporating the flavonoid extract into chitosan polymer.

  4. Converting citrus wastes into value-added products: Economic and environmently friendly approaches.

    PubMed

    Sharma, Kavita; Mahato, Neelima; Cho, Moo Hwan; Lee, Yong Rok

    2017-02-01

    Citrus fruits, including oranges, grapefruits, lemons, limes, tangerines, and mandarins, are among the most widely cultivated fruits around the globe. Its production is increasing every year due to rising consumer demand. Citrus-processing industries generate huge amounts of wastes every year, and citrus peel waste alone accounts for almost 50% of the wet fruit mass. Citrus waste is of immense economic value as it contains an abundance of various flavonoids, carotenoids, dietary fiber, sugars, polyphenols, essential oils, and ascorbic acid, as well as considerable amounts of some trace elements. Citrus waste also contains high levels of sugars suitable for fermentation for bioethanol production. However, compounds such as D-limonene must be removed for efficient bioethanol production. The aim of the present article was to review the latest advances in various popular methods of extraction for obtaining value-added products from citrus waste/byproducts and their potential utility as a source of various functional compounds. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Membrane Peeling-Induced Retinal Alterations on Intraoperative OCT in Vitreomacular Interface Disorders From the PIONEER Study.

    PubMed

    Ehlers, Justis P; Han, Jaehong; Petkovsek, Daniel; Kaiser, Peter K; Singh, Rishi P; Srivastava, Sunil K

    2015-11-01

    To assess retinal architectural alterations that occur following membrane peeling procedures and the impact of peel technique on these alterations utilizing intraoperative optical coherence tomography (iOCT). This is a subanalysis of the prospective PIONEER iOCT study of eyes undergoing a membrane peeling for a vitreomacular interface (VMI) disorder. Intraoperative scanning was performed with a microscope-mounted OCT system. Macroarchitectural alterations (e.g., full-thickness retinal elevations) and microarchitectural alterations (e.g., relative layer thickness alterations) were analyzed. Video/iOCT correlation was performed to identify instrument-tissue manipulations resulting in macroarchitectural alterations. One hundred sixty-three eyes were included in the macroarchitectural analysis. Instrumentation utilized for membrane peeling included forceps alone for 73 eyes (45%), combined diamond-dusted membrane scraper (DDMS) and forceps for 87 eyes (53%), and other techniques in three eyes (2%). Focal retinal elevations were identified in 45 of 163 eyes (28%). Video/iOCT correlation identified 69% of alterations involved forceps compared to 26% due to DDMS. Sixteen percent of retinal alterations persisted 1 month following surgery. The microarchitectural analysis included 134 eyes. Immediately following membrane peeling, there was a significant increase in the ellipsoid zone to retinal pigment epithelium height (+20%, P < 0.00001) and the cone outer segment tips to retinal pigment epithelium height (+18%, P < 0.00001). Significant subclinical retinal architectural changes occur during membrane peeling for VMI conditions. Differences in surgical instruments may impact these architectural alterations.

  6. Pseudohyperglycemia: Effects of Unwashed Hand after Fruit Peeling or Handling on Fingertips Blood Glucose Monitoring Results.

    PubMed

    Olamoyegun, M A; Oloyede, T; Adewoye, O G; Abdulkarim, S O; Adeleke, A A

    2016-01-01

    Self-monitoring of blood glucose (SMBG) is an important component of management for diabetes mellitus (DM), especially in T1DM and T2DM patients who are on insulin therapy. Adequate blood glucose monitoring and prompt intervention are necessary to prevent blood glucose (BG) fluctuation and delay long-term diabetes complications. People with DM are advised to clean their hands before SMBG to remove any dirt or food residue that might affect the reading. The study tested the hypothesis that falsely elevated BG levels from fingertip occur after peeling or handling fruits in an unwashed hand. Fifty apparently healthy nondiabetes volunteers were enrolled. Capillary BG samples were collected from the fingertips after peeling or handling apple, orange, banana, watermelon, and pawpaw, followed by no hand washing for 1 h, cleaning the fingertip with alcohol swab once, five times, and washing hand thoroughly with tap water and drying. These samples were then analyzed with two different glucose meters. The mean BG values, measured from fingertip blood samples after peeling, and handling any of the fruits followed by no hand washing were significantly high, even after cleaning fingertip with a swab of alcohol once. However, there were no significant difference in BG levels measured after peeling and handling fruits followed by hand washing and the level of BG before peeling and handling fruits. Handling of peeled fruits with no hand washing with tap water is associated with overestimation of capillary BG (Pseudohyperglycemia) monitored with glucose meters.

  7. FastICA peel-off for ECG interference removal from surface EMG.

    PubMed

    Chen, Maoqi; Zhang, Xu; Chen, Xiang; Zhu, Mingxing; Li, Guanglin; Zhou, Ping

    2016-06-13

    Multi-channel recording of surface electromyographyic (EMG) signals is very likely to be contaminated by electrocardiographic (ECG) interference, specifically when the surface electrode is placed on muscles close to the heart. A novel fast independent component analysis (FastICA) based peel-off method is presented to remove ECG interference contaminating multi-channel surface EMG signals. Although demonstrating spatial variability in waveform shape, the ECG interference in different channels shares the same firing instants. Utilizing the firing information estimated from FastICA, ECG interference can be separated from surface EMG by a "peel off" processing. The performance of the method was quantified with synthetic signals by combining a series of experimentally recorded "clean" surface EMG and "pure" ECG interference. It was demonstrated that the new method can remove ECG interference efficiently with little distortion to surface EMG amplitude and frequency. The proposed method was also validated using experimental surface EMG signals contaminated by ECG interference. The proposed FastICA peel-off method can be used as a new and practical solution to eliminating ECG interference from multichannel EMG recordings.

  8. Characterization of pectins extracted from pomegranate peel and their gelling properties.

    PubMed

    Abid, Mouna; Cheikhrouhou, S; Renard, Catherine M G C; Bureau, Sylvie; Cuvelier, Gérard; Attia, Hamadi; Ayadi, M A

    2017-01-15

    The composition of pomegranate peel, the main by-product during pomegranate processing, and some of the characteristics of the water-soluble pectins were investigated. Four tunisian pomegranate peels were subjected to hot aqueous extractions (86°C, 80min, 20mM nitric acid). Pomegranate peels yielded between 6.8% and 10.1% pectins. The extracted pectins were low methylated and were characterized by the predominance of homogalacturonan regions. Principal component analysis applied on FT-IR spectral data in the region between 4000 and 650cm(-1) differentiated the samples according to their degree of methylation. At pH 3, in the presence of 0.7% pectin, all solutions showed a rapid gel formation with G'>G″. With decreasing temperature from 90°C to 10°C, G' increased to reach a plateau at 10°C. The variation in the pectin gel formation between varieties was attributed to difference in pectin characteristics particularly the hydrodynamic volume and the neutral sugar content. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Impact behaviour of freeze-dried and fresh pomelo (Citrus maxima) peel: influence of the hydration state

    PubMed Central

    Thielen, Marc; Speck, Thomas; Seidel, Robin

    2015-01-01

    Pomelos (Citrus maxima) are known for their thick peel which—inter alia—serves as energy dissipator when fruits impact on the ground after being shed. It protects the fruit from splitting open and thus enables the contained seeds to stay germinable and to potentially be dispersed by animal vectors. The main part of the peel consists of a parenchymatous tissue that can be interpreted from a materials point of view as open pored foam whose struts are pressurized and filled with liquid. In order to investigate the influence of the water content on the energy dissipation capacity, drop weight tests were conducted with fresh and with freeze-dried peel samples. Based on the coefficient of restitution it was found that freeze-drying markedly reduces the relative energy dissipation capacity of the peel. Measuring the transmitted force during impact furthermore indicated a transition from a uniform collapse of the foam-like tissue to a progressive collapse due to water extraction. Representing the peel by a Maxwell model illustrates that freeze-drying not only drastically reduces the damping function of the dashpots but also stiffens the springs of the model. PMID:26543566

  10. Characterization of the PTW SourceCheck ionization chamber with the Valencia lodgment for (125)I seed verification.

    PubMed

    Tornero-López, Ana M; Torres Del Río, Julia; Ruiz, Carmen; Perez-Calatayud, Jose; Guirado, Damián; Lallena, Antonio M

    2015-12-01

    In brachytherapy using (125)I seed implants, a verification of the air kerma strength of the sources used is required. Typically, between 40 and 100 seeds are implanted. Checking all of them is unaffordable, especially when seeds are disposed in sterile cartridges. Recently, a new procedure allowing the accomplishment of the international recommendations has been proposed for the seedSelectron system of Elekta Brachytherapy. In this procedure, the SourceCheck ionization chamber is used with a special lodgment (Valencia lodgment) that allows to measure up to 10 seeds simultaneously. In this work we analyze this procedure, showing the feasibility of the approximations required for its application, as well as the effect of the additional dependence with the air density that shows the chamber model used. Uncertainty calculations and the verification of the approximation needed to obtain a calibration factor for the Valencia lodgment are carried out. The results of the present work show that the chamber dependence with the air density is the same whether the Valencia lodgment is used or not. On the contrary, the chamber response profile is influenced by the presence of the lodgment. The determination of this profile requires various measurements due to the nonnegligible variability found between different experiments. If it is considered, the uncertainty in the determination of the air-kerma strength increases from 0.5% to 1%. Otherwise, a systematic additional uncertainty of 1% would occur. This could be relevant for the comparison between user and manufacturer measurements that is mandatory in the case studied here. Copyright © 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  11. Peroxidase extraction from jicama skin peels for phenol removal

    NASA Astrophysics Data System (ADS)

    Chiong, T.; Lau, S. Y.; Khor, E. H.; Danquah, M. K.

    2016-06-01

    Phenol and its derivatives exist in various types of industrial effluents, and are known to be harmful to aquatic lives even at low concentrations. Conventional treatment technologies for phenol removal are challenged with long retention time, high energy consumption and process cost. Enzymatic treatment has emerged as an alternative technology for phenol removal from wastewater. These enzymes interact with aromatic compounds including phenols in the presence of hydrogen peroxide, forming free radicals which polymerize spontaneously to produce insoluble phenolic polymers. This work aims to extract peroxidase from agricultural wastes materials and establish its application for phenol removal. Peroxidase was extracted from jicama skin peels under varying extraction conditions of pH, sample-to-buffer ratio (w/v %) and temperature. Experimental results showed that extraction process conducted at pH 10, 40% w/v and 25oC demonstrated a peroxidase activity of 0.79 U/mL. Elevated temperatures slightly enhanced the peroxidase activities. Jicama peroxidase extracted at optimum extraction conditions demonstrated a phenol removal efficiency of 87.5% at pH 7. Phenol removal efficiency was ∼ 97% in the range of 30 - 40oC, and H2O2 dosage has to be kept below 100 mM for maximum removal under phenol concentration tested.

  12. Hesperidin, nobiletin, and tangeretin are collectively responsible for the anti-neuroinflammatory capacity of tangerine peel (Citri reticulatae pericarpium).

    PubMed

    Ho, Su-Chen; Kuo, Chun-Ting

    2014-09-01

    Inhibiting microglial activation-mediated neuroinflammation has become a convincing target for the development of functional foods to treat neurodegenerative diseases. Tangerine peel (Citri reticulatae pericarpium) has potent anti-inflammatory capacity; however, its anti-neuroinflammatory capacity and the corresponding active compounds remain unclear. To this end, the composition of a tangerine peel ethanolic extract was analysed by LC-MS, and the anti-neuroinflammatory ability was evaluated using a lipopolysaccharide (LPS)-activated BV2 microglia culture system. Hesperidin is the most predominant flavonoid in tangerine peel, followed by tangeretin and nobiletin. Among the eight tested flavanone glycosides and polymethoxy flavones, only nobiletin displayed a capacity of>50% to inhibit LPS-induced proinflammatory NO, TNF-α, IL-1β and IL-6 secretion at a concentration of 100 μM. At 2 mg/ml, tangerine peel extract attenuated LPS-induced NO, TNF-α, IL-1β and IL-6 secretion by 90.6%, 80.2%, 66.7%, and 86.8%, respectively. Hesperidin, nobiletin, and tangeretin individually (at concentrations of 135, 40, and 60 μM, respectively) in 2 mg/ml tangerine peel extract were only mildly inhibitory, whereas in combination, they significantly inhibited LPS-induced proinflammatory cytokine expression at levels equal to that of 2 mg/ml tangerine peel extract. Overall, tangerine peel possesses potent anti-neuroinflammatory capacity, which is attributed to the collective effect of hesperidin, nobiletin, and tangeretin. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. [Internal limiting membrane peeling as prophylaxis of epimacular membrane formation in eyes undergoing vitrectomy for rhegmatogenous retinal detachement].

    PubMed

    Hejsek, L; Dusová, J; Stepanov, A; Rozsíval, P

    2014-06-01

    Rhegmatogenous retinal detachment is a serious condition that can significantly impair visual function, even after a successful surgery. One of the complications that can significantly impair visual acuity in the postoperative period is a development of the epimacular membrane (ERM). The aim of this work is to monitor the effect of peeling of the internal limiting membrane (ILM) in the macula at the anatomical and functional results in the postoperative period, especially with regard to the development of ERM. Prospective study of 21 eyes, which underwent peeling of ILM during pars plana vitrectomy for rhegmatogenous retinal detachment (on detached macula). The ILM peeling was done without using decalin during this procedure. We tested best corrected visual acuity (BCVA) and followed fundus biomicroscopic findings. Proliferative vitreoretinopathy (PVR) was evaluated according to the recommendations of the Retina Society Terminology Committee. To exclude the development of ERM in the macula optical coherence tomography (OCT) was performed at the end of the 18-month follow-up period. In total, the results of 21 eyes of 21 patients who underwent PPV for rhegmatogenous retinal detachment were evaluated. In all of them was during PPV performed ILM peeling on detached macula, these are followed prospectively. ILM peeling without using decalin was sufficient in all eyes. All eyes with ILM peeling did not develop ERM at the end of the follow-up period. ILM peeling during PPV for rhegmatogenous retinal detachment reduces the risk of developing secondary ERM.

  14. [Changes in polyamine levels in Citrus sinensis Osb. cv. Valencia callus during somatic embryogenesis].

    PubMed

    Liu, Hua-Ying; Xiao, Lang-Tao; Lu, Xu-Dong; Hu, Jia-Jin; Wu, Shun; He, Chang-Zheng; Deng, Xiu-Xin

    2005-06-01

    Somatic embryogenetic capability and changes in polyamine level and their relationship were analyzed using the long-term (8 years) subcultured calli of Citrus sinensis Osb. cv. Valencia as materials. The results showed that endogenous polyamine contents in embryogenic calli were higher than those in non-embryogenic calli, and the embryogenetic capability was positively correlated to the levels of endogenous polyamines. When the calli were transferred to a differentiation medium, the putrescine content rapidly increased and reached a peak, then fell gradually. Applying exogenous putrescine raised the embryogenesis frequency and endogenous putrescine level. It indicated that increase in putrescine content at early stage of differentiation promoted embryogenesis. With the development of somatic embryo, spermidine content reached its the highest level at globular embryo stage, spermine content rose and reached a peak at a later stage of globular embryo development. Furthermore, changes of the putrescine, spermidine and spermine contents during somatic embryogenesis were similar in Valencia calli which had different ploidy levels, but their contents decreased following the increasing of ploidy level. Changes in arginine decarboxylase activity were positively correlated to the polyamine levels, which suggest that the later is a key factor in regulating the polyamine levels during somatic embryogenesis in citrus plants.

  15. Postoperative eccentric macular holes after vitrectomy and internal limiting membrane peeling.

    PubMed

    Brouzas, Dimitrios; Dettoraki, Maria; Lavaris, Anastasios; Kourvetaris, Dimitrios; Nomikarios, Nikolaos; Moschos, Marilita M

    2017-06-01

    The purpose of this study was to describe the incidence, clinical characteristics, and outcome of eccentric macular holes presenting after vitrectomy and internal limiting membrane (ILM) peeling for the treatment of macular pathology and discuss the pathogenesis of holes formation. A retrospective, noncomparative, interventional case-series study of five patients who developed eccentric macular holes postoperatively following vitrectomy in 198 consecutive patients who underwent ILM peeling for idiopathic macular hole and epiretinal membrane formation between 2008 and 2015. Five patients (2.5 %) developed full-thickness eccentric macular holes postoperatively. Three patients presented with a single eccentric macular hole, one patient had an eccentric hole after a failed idiopathic macular hole surgery and one patient developed four eccentric macular holes. The mean diameter of the holes was 584 μm (range 206-1317 μm) and the average time of holes formation after vitrectomy was 27.7 weeks (range 1-140 weeks). Postoperative best-corrected visual acuity ranged from "counting fingers" to 20/25. The eyes with the holes distant from the fovea had the best final visual acuity. No further intervention was attempted and no complications occurred. The mean follow-up time was 26.8 months. The postoperative macular holes after vitrectomy and ILM peeling were variable in number, size, and time of appearance but remained stable and were not associated with any complications. The pathogenesis of macular holes is most consistent with contraction of the residual ILM or secondary epimacular proliferation probably stimulated by ILM peeling.

  16. Image analysis to evaluate the browning degree of banana (Musa spp.) peel.

    PubMed

    Cho, Jeong-Seok; Lee, Hyeon-Jeong; Park, Jung-Hoon; Sung, Jun-Hyung; Choi, Ji-Young; Moon, Kwang-Deog

    2016-03-01

    Image analysis was applied to examine banana peel browning. The banana samples were divided into 3 treatment groups: no treatment and normal packaging (Cont); CO2 gas exchange packaging (CO); normal packaging with an ethylene generator (ET). We confirmed that the browning of banana peels developed more quickly in the CO group than the other groups based on sensory test and enzyme assay. The G (green) and CIE L(∗), a(∗), and b(∗) values obtained from the image analysis sharply increased or decreased in the CO group. And these colour values showed high correlation coefficients (>0.9) with the sensory test results. CIE L(∗)a(∗)b(∗) values using a colorimeter also showed high correlation coefficients but comparatively lower than those of image analysis. Based on this analysis, browning of the banana occurred more quickly for CO2 gas exchange packaging, and image analysis can be used to evaluate the browning of banana peels. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Optimal growth condition of earthworms and their vermicompost features during recycling of five different fresh fruit and vegetable wastes.

    PubMed

    Huang, Kui; Xia, Hui; Li, Fusheng; Wei, Yongfen; Cui, Guangyu; Fu, Xiaoyong; Chen, Xuemin

    2016-07-01

    This study aimed to promote vermicomposting performance for recycling fresh fruit and vegetable wastes (FVWs) and to assess microbial population and community of final products. Five fresh FVWs including banana peels, cabbage, lettuce, potato, and watermelon peels were chosen as earthworms' food. The fate test of earthworms showed that 30 g fresh FVWs/day was the optimal loading and the banana peels was harmful for the survival of Eisenia fetida. The followed vermicomposting test revealed lower contents of total carbon and weaker microbial activity in final vermicomposts, relative to those in compared systems without earthworms worked. The leachate from FVWs carried away great amounts of nutrients from reactors. Additionally, different fresh FVWs displayed dissimilar stabilization process. Molecular biological approaches revealed that earthworms could broaden bacterial diversity in their products, with significant greater populations of actinobacteria and ammonia oxidizing bacteria than in control. This study evidences that vermicomposting efficiency differs with the types and loadings of fresh FVWs and vermicomposts are rich in agricultural probiotics.

  18. EFFECTS OF INTERNAL LIMITING MEMBRANE PEELING COMBINED WITH REMOVAL OF IDIOPATHIC EPIRETINAL MEMBRANE: A Systematic Review of Literature and Meta-Analysis.

    PubMed

    Azuma, Kunihiro; Ueta, Takashi; Eguchi, Shuichiro; Aihara, Makoto

    2017-10-01

    To evaluate the effects on postoperative prognosis of internal limiting membrane (ILM) peeling in conjunction with removal of idiopathic epiretinal membranes (ERMs). MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), and EMBASE were systematically searched for studies that compared ILM peeling with no ILM peeling in surgery to remove idiopathic ERM. Outcome measures were best-corrected visual acuity, central macular thickness, and ERM recurrence. Studies that compared ILM peeling with no ILM peeling for the treatment of idiopathic ERM were selected. Sixteen studies that included 1,286 eyes were selected. All the included studies were retrospective or prospective comparative studies; no randomized controlled study was identified. Baseline preoperative best-corrected visual acuity and central macular thickness were equal between ILM peeling and no ILM peeling groups. Postoperatively, there was no statistically significant difference in best-corrected visual acuity (mean difference 0.01 logarithm of the minimum angle of resolution [equivalent to 0.5 Early Treatment Diabetic Retinopathy Study letter]; 95% CI -0.05 to 0.07 [-3.5 to 2.5 Early Treatment Diabetic Retinopathy Study letters]; P = 0.83) or central macular thickness (mean difference 13.13 μm; 95% CI -10.66 to 36.93; P = 0.28). However, the recurrence rate of ERM was significantly lower with ILM peeling than with no ILM peeling (odds ratio 0.25; 95% CI 0.12-0.49; P < 0.0001). Currently available evidence in the literature indicates that additional ILM peeling in vitrectomy for idiopathic ERM could result in a significantly lower ERM recurrence rate, but it does not significantly influence postoperative best-corrected visual acuity and central macular thickness.

  19. Travel and Tourism Students' Needs in Valencia (Spain): Meeting their Professional Requirements in the ESP Classroom

    ERIC Educational Resources Information Center

    Garcia Laborda, Jesus

    2003-01-01

    The main purpose of this paper is to describe the basic findings obtained as a result of the implementation of two projects of Computer and Information Technologies held in Valencia (Spain) between 2002 and 2003 with 92 second year university students enrolled in English as a foreign language to find out their ICT and foreign language needs both…

  20. Application of banana peels waste as adsorbents for the removal of CO2, NO, NOx, and SO2 gases from motorcycle emissions

    NASA Astrophysics Data System (ADS)

    Viena, V.; Elvitriana; Wardani, S.

    2018-03-01

    The aims of the study were to investigate the application of banana peels as adsorbent for the removal of CO, NO, NOx and SO2 gases from motorcycles emissions. The effect of differents thermal activation on the characteristics of banana peels adsorbent (BPA) such as moisture content, ash content, volatile matter and fixed carbon has been studied using proximate analysis. The study of Iodine adsorption capacity of BPA was obtained at 952 mg/g adsorbent. Structure and morphology of BPA were characterized by Fourier transform infrared (FTIR) and field emission scanning electron microscopy (SEM). The results showed that BPA could significantly adsorbed the CO and SO2 gases emissions from motorcycles, but not applicable for NO, NOx gases. After 10 minutes of flue gas analysis at idle mode using BPA adsorption tube, CO gas could be totally removed, from initial 19618 ppm to 0 ppm, while SO2 gas could also be totally removed from 24523 ppm to 0 ppm. SEM test showed that temperature of activation had significant effect on the size of pores of BPA formed. BPA was suitable for application in removing CO and SO2 gases emissions from motorcycles and it helps to reduce the green house gas effects of fossil fuel to the environment.

  1. The experimental vibrational infrared spectrum of lemon peel and simulation of spectral properties of the plant cell wall

    NASA Astrophysics Data System (ADS)

    Berezin, K. V.; Shagautdinova, I. T.; Chernavina, M. L.; Novoselova, A. V.; Dvoretskii, K. N.; Likhter, A. M.

    2017-09-01

    The experimental vibrational IR spectra of the outer part of lemon peel are recorded in the range of 3800-650 cm-1. The effect of artificial and natural dehydration of the peel on its vibrational spectrum is studied. It is shown that the colored outer layer of lemon peel does not have a noticeable effect on the vibrational spectrum. Upon 28-day storage of a lemon under natural laboratory conditions, only sequential dehydration processes are reflected in the vibrational spectrum of the peel. Within the framework of the theoretical DFT/B3LYP/6-31G(d) method, a model of a plant cell wall is developed consisting of a number of polymeric molecules of dietary fibers like cellulose, hemicellulose, pectin, lignin, some polyphenolic compounds (hesperetin glycoside-flavonoid), and a free water cluster. Using a supermolecular approach, the spectral properties of the wall of a lemon peel cell was simulated, and a detailed theoretical interpretation of the recorded vibrational spectrum is given.

  2. Characterization of bioplastic based from cassava crisp home industrial waste incorporated with chitosan and liquid smoke

    NASA Astrophysics Data System (ADS)

    Fathanah, U.; Lubis, M. R.; Nasution, F.; Masyawi, M. S.

    2018-03-01

    Cassava peel (Manihot utilissima) is waste of agricultural result that is much potential as raw material of bioplastic making. This research focuses on bioplastic making from cassava peel. It aims to characterize the resulted bioplastic (mechanical and physical properties, SEM analysis, FTIR analysis and time test of bioplastic degradation). The bioplastic preparation takes place by mixing starch of cassava peel and chitosan (20, 30, 40 and 50% w/w), glycerol 30% w/w as plasticizer, and liquid smoke (0, 1 and 2 mL) as antimicrobial agent. The research result shows the highest value of tensile strength is 96.04 MPa, the highest elongation at break is 52.27%, and the value of water-resistant test is 22.68%. Morphology analysis by using SEM shows uneven surface and there is fracture in its cross-section. The analysis of functional group by FTIR shows the presence of functional groups of O–H (hydroxyl), N–H (amine), dan CH3–O (ether). The fastest complete degradation of bioplastic occurs in 45 days, and the longest occurs in 57 days.

  3. Elkmont Vehicle Bridge, Construction PeelAway Great Smoky Mountains National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Elkmont Vehicle Bridge, Construction Peel-Away - Great Smoky Mountains National Park Roads & Bridges, Elkmont Vehicle Bridge, Spanning Little River at Elkmont Campground, Gatlinburg, Sevier County, TN

  4. Comparative antioxidant effect of BHT and water extracts of banana and sapodilla peels in raw poultry meat.

    PubMed

    Devatkal, Suresh K; Kumboj, Ritu; Paul, Devosmita

    2014-02-01

    Antioxidant properties of banana (Musa paradisiaca) and Sapodilla/Chikoo (Manilkara zapota) peel extracts in chicken patties were evaluated. Four treatments viz., I. Control (meat + 2% salt), II.BHT (meat + 2% salt + 0.1% BHT), III. BPE (meat + 2% salt + 2% banana peel extract) and IV. SPE (meat + 2% salt + 2% sapodilla/chikoo peel extract) were compared for changes in colour and lipid oxidation during 8 days refrigerated storage (4 ± °C). The average phenolic content was 550.2 and 550.8 mg gallic acid equivalent per 10 g peel in BPE and SPE respectively. Free radical scavenging activity was 66.9 and 67.8% in BPE and SPE respectively. Banana peel extract had significantly (P < 0.05) higher reducing activity (1.6) as compared to sapodilla peel extract (0.91). During refrigerated storage period, all color parameters decreased significantly in all treatments. Observation on lipid oxidation showed a significantly (P < 0.05) higher TBARS values in control than other three treatments. The increase in TBARS from initial day of storage to last day of storage was highest in control (514.3%) as compared to BHT (387.7%), BPE (370.6%) and SPE (383.7%). Both synthetic antioxidants and natural extracts significantly decreased the TBARS. The average decrease in TBARS values during 8 days of storage was 56.8%, 38.3% and 37.2% values in BHT, BPE and SPE treatments respectively. Therefore, it was concluded that water extracts obtained from banana and sapodilla peels could be explored as natural antioxidants in poultry meat and meat products.

  5. Functional analysis of unfermented and fermented citrus peels and physical properties of citrus peel-added doughs for bread making.

    PubMed

    Shyu, Yung-Shin; Lu, Tzu-Chi; Lin, Chuan-Chuan

    2014-12-01

    Several studies have indicated citrus peels (CP) contain specific methoxy flavones, e.g. nobiletin and tangeretin, which have been shown to prevent numerous diseases. However, research reports regarding their application as food additive in healthy baked products is scarce. In our study, both unfermented (UF) and fermented (F) citrus peels were processed under different dry hot-air temperatures to make four citrus peel powders , UF-100 °C,UF-150 °C, F-100 °C, F-150 °C, respectively. The analysis of the basic components and nutraceuticals as well as antioxidant activity were conducted. Various percentages of CP were added to dough and toast bread for physical property and sensory evaluations. The results indicated the contents of crude proteins (3.3-4.3 mg/g) and fibers (10.9-14.9 %) among the four samples were similar. The UF extracts showed better antioxidant activities than F extracts. HPLC analysis indicated the contents of hesperidine, nobiletin and tangeretin in CP extracts were UF-150 °C > UF-100 °C. Farinograph analysis indicated a linear relation between CP powder content and the parameters of the physical properties of dough. A high percentage of fibrous CP powder in dough increases the water adsorption capacity of the dough, resulting in a decrease in its stability The sensory evaluation results indicated a greater acceptability of UF-added toast bread relative to the F-added one. Among these, according to the statistical anaylsis, the UF-150 °C 4 % and UF-100 °C 6 % groups were the best and F-150 °C 2 % group was the poorest in overall acceptability.

  6. The link between the peel force of adhesive dressings and subjective discomfort in volunteer subjects.

    PubMed

    Dykes, P J; Heggie, R

    2003-07-01

    The study compared the level of discomfort experienced by healthy volunteers on the removal of a range of adhesive wounds. This was an open, within subject comparative study of six adhesive dressings in 24 volunteers. The test site was the lower back. Allocation of test materials to the test sites was randomised. The peel force of removal was recorded after 24 hours of application using a device that removed the dressing at a constant speed and angle to the skin surface. The discomfort experienced at each removal was assessed by the subjects themselves using an electronic visual analogue scale. Overall, Mepilex Border was given a significantly lower discomfort score (p < or = 0.01) by the subjects than the other dressings. There were no clear differences between the five other products tested. Tielle and Allevyn Adhesive had significantly higher (p < or = 0.05) peel force than the other products. Mepilex Border caused less discomfort on removal than Duoderm Extra Thin, Biatain and Versiva, even though the peel force was similar. Tielle and Allevyn had higher peel force, but the levels of discomfort were not significantly higher for these products. It may be that the level of discomfort experienced by subjects on removal of an adhesive dressing is not entirely dependent on the peel force and that other aspects of the interaction of the skin surface and adhesive play a role.

  7. Characterization of flavonoids and pectins from bergamot (Citrus bergamia Risso) peel, a major byproduct of essential oil extraction.

    PubMed

    Mandalari, Giuseppina; Bennett, Richard N; Bisignano, Giuseppe; Saija, Antonella; Dugo, Giacomo; Lo Curto, Rosario B; Faulds, Craig B; Waldron, Keith W

    2006-01-11

    Bergamot peel is an underutilized byproduct of the essential oil and juice-processing industry. As with other Citrus peels, it still contains exploitable components, such as pectins and flavonoids. Commercial glycoside hydrolases, specifically a combination of pectolytic and cellulolytic enzymes, solubilized a high percentage of the material (81.94%). The flavonoid profile of the peel consisted of characteristic Citrus species flavanone rutinosides and neohesperosides derived from naringenin, eriodictyol, and hesperetin. In addition, a number of minor flavanone and flavone glycosides, not found in orange and lemon peels, were identified. The majority of flavonoids were extracted in the two 70% v/v EtOH extractions. Processing this material clearly has economic potential leading to low environmental impact.

  8. Leaching behavior of total organic carbon, nitrogen, and phosphorus from banana peel.

    PubMed

    Jiang, Ruixue; Sun, Shujuan; Xu, Yan; Qiu, Xiudong; Yang, Jili; Li, Xiaochen

    2015-01-01

    The leaching behavior of organic carbon and nutrient compounds from banana peel (BP) was investigated in batch assays with respect to particle size, contact time, pH value, and temperature. The granularity, contact time, pH, and temperature caused no significant effects on the leaching of total phosphorus (TP) from the BP. The maximum leached total nitrogen (TN) content was found at pH 5.0 and 90 minutes, while no significant effects were caused by the granularity and temperature. The maximum leached total organic carbon (TOC) content was found by using a powder of 40 mesh, 150 minutes and at pH 6.0, while the temperature had no effect on the TOC leaching. The proportions of the TN, TP, and TOC contents leached from the dried BP ranged from 33.6% to 40.9%, 60.4% to 72.7%, and 8.2% to 9.9%, respectively, indicating that BP could be a potential pollution source for surface and ground water if discharged as domestic waste or reutilized without pretreatment.

  9. The role of red dragon fruit peel (Hylocereus polyrhizus) to improvement blood lipid levels of hyperlipidaemia male mice

    NASA Astrophysics Data System (ADS)

    Hernawati; Setiawan, N. A.; Shintawati, R.; Priyandoko, D.

    2018-05-01

    The purpose of this research was to know the role of red dragon fruit peel powder to total cholesterol, triglyceride, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and weight in the male hyperlipidaemic Balb-C mice (Mus musculus). This study used a completely randomized design (CRD) and four replicates for each dose treatments. Samples were 24 male mice that divided into six groups i.e. positive and negative controls, doses of 50; 100; 150 and 200 mg/kgBW/days red dragon fruit peel powder. Before being given treatment, mice were given feed containing high fat for 20 days until experiencing conditions hyperlipidaemia. The red dragon fruit peel powder was given at oral with used gavage for 30 days. Blood samples were taken from the tail on vena caudalis. Blood lipid samples were analysed at enzymatic with BIOLABO kits. The results of this study indicate that after administration of red dragon fruit peel powder total cholesterol levels, triglycerides and LDL-c decreased, along with increasing doses of red dragon fruit peel powder for 30 days. Furthermore showed that dragon fruit powder can increase HDL-c levels. The conclusion of this research was The red dragon fruit peel powder can improve blood lipid level of male Balb-c mice hyperlipidaemia.

  10. Optimization of extraction of novel pectinase enzyme discovered in red pitaya (Hylocereus polyrhizus) peel.

    PubMed

    Zohdi, Nor Khanani; Amid, Mehrnoush

    2013-11-20

    Plant peels could be a potential source of novel pectinases for use in various industrial applications due to their broad substrate specificity with high stability under extreme conditions. Therefore, the extraction conditions of a novel pectinase enzyme from pitaya peel was optimized in this study. The effect of extraction variables, namely buffer to sample ratio (2:1 to 8:1, X₁), extraction temperature (-15 to +25 °C, X₂) and buffer pH (4.0 to 12.0, X₃) on specific activity, temperature stability, storage stability and surfactant agent stability of pectinase from pitaya peel was investigated. The study demonstrated that the optimum conditions for the extraction of pectinase from pitaya sources could improve the enzymatic characteristics of the enzyme and protect its activity and stability during the extraction procedure. The optimum extraction conditions cause the pectinase to achieve high specific activity (15.31 U/mg), temperature stability (78%), storage stability (88%) and surfactant agent stability (83%). The most desirable conditions to achieve the highest activity and stability of pectinase enzyme from pitaya peel were the use of 5:1 buffer to sample ratio at 5 °C and pH 8.0.

  11. Outdoor Education and the Peel Board of Education.

    ERIC Educational Resources Information Center

    Shaw, Katherine

    1994-01-01

    Describes efforts of an advocacy group of parents, outdoor educators, and classroom teachers to preserve outdoor education in Peel in the face of budget cuts. Despite efforts, a task force recommended the elimination of numerous teaching positions, resulting in reduced programming at outdoor education centers. (LP)

  12. Shelf life and microbial profile of peeled onions

    USDA-ARS?s Scientific Manuscript database

    The increased usage of peeled onions over the past ten years by food service operations and fast-food restaurants has been plagued by black mold decay during cold-chain storage. This study examined the epiphytic microbiological distribution on onions and what effects various processing steps have on...

  13. [Spontaneous peeling of the epimacular membrane after cryotherapy of retinal vasoproliferative tumors: report of a case].

    PubMed

    Coulier, J; Gribomont, A C; De Potter, P

    2013-01-01

    Epimacular membranes when responsible for a significant loss of visual acuity, generally require treatment by vitrectomy and peeling of the membrane. We report the case of a spontaneous peeling of a macular pucker after cryotherapy of peripheral retinal vasoproliferative tumors. Review of the literature.

  14. Production of cellulases from Aspergillus niger NS-2 in solid state fermentation on agricultural and kitchen waste residues.

    PubMed

    Bansal, Namita; Tewari, Rupinder; Soni, Raman; Soni, Sanjeev Kumar

    2012-07-01

    Various agricultural and kitchen waste residues were assessed for their ability to support the production of a complete cellulase system by Aspergillus niger NS-2 in solid state fermentation. Untreated as well as acid and base-pretreated substrates including corn cobs, carrot peelings, composite, grass, leaves, orange peelings, pineapple peelings, potato peelings, rice husk, sugarcane bagasse, saw dust, wheat bran, wheat straw, simply moistened with water, were found to be well suited for the organism's growth, producing good amounts of cellulases after 96 h without the supplementation of additional nutritional sources. Yields of cellulases were higher in alkali treated substrates as compared to acid treated and untreated substrates except in wheat bran. Of all the substrates tested, wheat bran appeared to be the best suited substrate producing appreciable yields of CMCase, FPase and β-glucosidase at the levels of 310, 17 and 33 U/g dry substrate respectively. An evaluation of various environmental parameters demonstrated that appreciable levels of cellulases could be produced over a wide range of temperatures (20-50 °C) and pH levels (3.0-8.0) with a 1:1.5 to 1:1.75 substrate to moisture ratio. Copyright © 2012 Elsevier Ltd. All rights reserved.

  15. Physical Characteristics, Chemical Composition, Organoleptic Test And The Number Of Microbes In The Biscuits With Addition Of Flour Banana Peels

    NASA Astrophysics Data System (ADS)

    Hernawati; Aryani, A.; Shintawati, R.

    2017-02-01

    The purpose of this study to analyze the physical characteristics, chemical composition and organoleptic test of biscuit flour with the addition of flour banana peel. Materials used are banana peels Kepok. Kepok banana peel has been found to contain high fiber food. Biscuit-making stage includes the formation of cream, adding flour and wheat flour dietary fiber from banana peels to concentrations of 0% as control, 25%, 50% and 75% of 100 grams of wheat flour; mixing; molding; baking in the oven for 20-25 minutes with a temperature of 180°C. Parameters to be measured, namely the physical characteristics include: hardness, softness, consistency, crispness. Furthermore, the biscuits were tested by chemical analysis (proximate). Organoleptic test include: aroma, taste, mouthfeel, aftertaste. Data were analyzed statistically using SAS computing programs. Physical and organoleptic test results biscuits with the addition of flour banana peels has sufficient level of preference between like-liked. Based on the results of the proximate analysis of biscuits with the addition of flour banana peels has generally been in accordance with the National Standards of Indonesia (SNI). Conclusion of the study that the addition of flour banana peels in biscuits has the potential to become functional foods that contain high fiber.

  16. Microwave-assisted extraction of pectin from cocoa peel

    NASA Astrophysics Data System (ADS)

    Sarah, M.; Hanum, F.; Rizky, M.; Hisham, M. F.

    2018-02-01

    Pectin is a polymer of d-galacturonate acids linked by β-1,4 glycosidic bond. This study isolates pectin from cocoa peel (Theobroma cacao) using citric acid as solvent by microwave-assisted extraction method. Cocoa peels (moisture content of 10%) with citric acid solution (pH of 1.5) irradiated by microwave energy at various microwave power (180, 300, 450 and 600 W) for 10, 15, 20, 25 and 30 minutes respectively. Pectin obtained from this study was collected and filtrated by adding 96% ethanol to precipitate the pectin. The best results obtained from extraction process using microwave power of 180 Watt for 30 minutes. This combination of power and time yielded 42.3% pectin with moisture content, ash content, weight equivalent, methoxyl content and galacturonate levels were 8.08%, 5%, 833.33 mg, 6.51% and 58,08%, respectively. The result finding suggested that microwave-assisted extraction method has a great potency on the commercial pectin production.

  17. Quality assurance of alpha-particle dosimetry using peeled-off Gafchromic EBT3® film

    NASA Astrophysics Data System (ADS)

    Ng, C. Y. P.; Chun, S. L.; Yu, K. N.

    2016-08-01

    A novel alpha-particle dosimetry technique using Gafchromic EBT3 film has recently been proposed for calibrating the activity of alpha-emitting radiopharmaceuticals. In the present paper, we outlined four measures which could further help assure the quality of the method. First, we suggested an alternative method in fabricating the peeled-off EBT3 film. Films with a chosen size were cut from the original films and all the edges were sealed with silicone. These were immersed into deionized water for 19 d and the polyester covers of the EBT3 films could then be easily peeled off. The active layers in these peeled-off EBT3 films remained intact, and these films could be prepared reproducibly with ease. Second, we proposed a check on the integrity of the peeled-off film by comparing the responses of the pristine and peeled-off EBT3 films to the same X-ray irradiation. Third, we highlighted the importance of scanning directions of the films. The ;landscape; and ;portrait; scanning directions were defined as the scanning directions perpendicular and parallel to the long edge of the original EBT3 films, respectively. Our results showed that the responses were different for different scanning directions. As such, the same scanning direction should be used every time. Finally, we cautioned the need to confirm the uniformity of the alpha-particle source used for calibration. Radiochromic films are well known for their capability of providing two-dimensional dosimetric information. As such, EBT3 films could also be conveniently used to check the uniformity of the alpha-particle source.

  18. Keratolysis exfoliativa (dyshidrosis lamellosa sicca): a distinct peeling entity.

    PubMed

    Chang, Y Y; van der Velden, J; van der Wier, G; Kramer, D; Diercks, G F H; van Geel, M; Coenraads, P J; Zeeuwen, P L J M; Jonkman, M F

    2012-11-01

    Keratolysis exfoliativa (KE), also known as dyshidrosis lamellosa sicca, is a palmoplantar dermatosis characterized by air-filled blisters and collarette desquamation. It has been regarded as a subtype of dyshidrotic eczema, a fungal infection or a dermatophytid reaction. KE may also resemble acral peeling skin syndrome and localized epidermolysis bullosa simplex. Although KE is a common disorder, it is a rarely reported and is an under-recognized dermatosis. To delineate the characteristic features of KE. We investigated the clinical, immunohistopathological, ultrastructural and molecular features of KE. Patients were included from the clinical records. Additional diagnostic research consisted of mutation analysis of the candidate genes TGM5, KRT5, KRT14, FLG, SPINK6 and SPINK9. A total of 24 patients with KE were identified, six with familial and 18 with sporadic KE. Lesions consisted of air-filled blisters only on palmoplantar skin, followed by collarette and lamellar peeling. Both light microscopy and electron microscopy showed cleavage and partially degraded corneodesmosomes within the stratum corneum, whereas immunofluorescence microscopy showed normal expression of corneodesmosomal components. No mutations were found in TGM5, KRT5/14 and SPINK6/9. There was no clear link with atopy or with FLG mutations. Our study suggests premature corneodesmolysis as the main pathological mechanism of this palmoplantar skin disorder. We conclude that KE appears to be a distinct peeling entity. © 2012 The Authors. BJD © 2012 British Association of Dermatologists.

  19. Determination of polymethoxylated flavones in peels of selected Jamaican and Mexican citrus (Citrus spp.) cultivars by high-performance liquid chromatography.

    PubMed

    Green, Curtis O; Wheatley, Andrew O; Osagie, Anthony U; St A Morrison, Errol Y; Asemota, Helen N

    2007-01-01

    The concentrations of the polymethoxylated flavones (PMFs) in peels of selected citrus cultivars grown in Jamaica and Mexico were determined. The PMFs were extracted from sun-dried citrus peels with reagent-grade methanol. Analyses were carried out by reverse-phase HPLC and UV detection. The column used was a C(18) 5 microm (150 x 4.6 mm) Discovery column. Elution was in the gradient mode, using a ternary mobile phase. The results showed that all the citrus cultivars used contained at least three of the six major PMFs quantified. Ortanique peel contained the highest quantity of PMFs (34,393 +/- 272 ppm), followed by tangerine (28,389 +/- 343 ppm) and Mexican sweet orange (sample 1; 21,627 +/- 494 ppm). The major PMFs, i.e. sinensetin, nobiletin, tangeretin, heptamethoxyflavone, tetramethylscutellarein and hexamethyl-o-quercetagetin, present in the peels of 20 citrus cultivars, was quantified. The results were compared with those of Florida citrus peels. A large amount of citrus peels and byproducts are produced in the Caribbean which could provide a cheap and convenient source of PMFs. Copyright 2006 John Wiley & Sons, Ltd.

  20. Targeting excessive free radicals with peels and juices of citrus fruits: grapefruit, lemon, lime and orange.

    PubMed

    Guimarães, Rafaela; Barros, Lillian; Barreira, João C M; Sousa, M João; Carvalho, Ana Maria; Ferreira, Isabel C F R

    2010-01-01

    A comparative study between the antioxidant properties of peel (flavedo and albedo) and juice of some commercially grown citrus fruit (Rutaceae), grapefruit (Citrus paradisi), lemon (Citrus limon), lime (Citrusxaurantiifolia) and sweet orange (Citrus sinensis) was performed. Different in vitro assays were applied to the volatile and polar fractions of peels and to crude and polar fraction of juices: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity, reducing power and inhibition of lipid peroxidation using beta-carotene-linoleate model system in liposomes and thiobarbituric acid reactive substances (TBARS) assay in brain homogenates. Reducing sugars and phenolics were the main antioxidant compounds found in all the extracts. Peels polar fractions revealed the highest contents in phenolics, flavonoids, ascorbic acid, carotenoids and reducing sugars, which certainly contribute to the highest antioxidant potential found in these fractions. Peels volatile fractions were clearly separated using discriminant analysis, which is in agreement with their lowest antioxidant potential. Copyright 2009 Elsevier Ltd. All rights reserved.

  1. Peel-and-Stick: Mechanism Study for Efficient Fabrication of Flexible/Transparent Thin-film Electronics

    NASA Astrophysics Data System (ADS)

    Lee, Chi Hwan; Kim, Jae-Han; Zou, Chenyu; Cho, In Sun; Weisse, Jeffery M.; Nemeth, William; Wang, Qi; van Duin, Adri C. T.; Kim, Taek-Soo; Zheng, Xiaolin

    2013-10-01

    Peel-and-stick process, or water-assisted transfer printing (WTP), represents an emerging process for transferring fully fabricated thin-film electronic devices with high yield and fidelity from a SiO2/Si wafer to various non-Si based substrates, including papers, plastics and polymers. This study illustrates that the fundamental working principle of the peel-and-stick process is based on the water-assisted subcritical debonding, for which water reduces the critical adhesion energy of metal-SiO2 interface by 70 ~ 80%, leading to clean and high quality transfer of thin-film electronic devices. Water-assisted subcritical debonding is applicable for a range of metal-SiO2 interfaces, enabling the peel-and-stick process as a general and tunable method for fabricating flexible/transparent thin-film electronic devices.

  2. Peel-and-stick: mechanism study for efficient fabrication of flexible/transparent thin-film electronics.

    PubMed

    Lee, Chi Hwan; Kim, Jae-Han; Zou, Chenyu; Cho, In Sun; Weisse, Jeffery M; Nemeth, William; Wang, Qi; van Duin, Adri C T; Kim, Taek-Soo; Zheng, Xiaolin

    2013-10-10

    Peel-and-stick process, or water-assisted transfer printing (WTP), represents an emerging process for transferring fully fabricated thin-film electronic devices with high yield and fidelity from a SiO2/Si wafer to various non-Si based substrates, including papers, plastics and polymers. This study illustrates that the fundamental working principle of the peel-and-stick process is based on the water-assisted subcritical debonding, for which water reduces the critical adhesion energy of metal-SiO2 interface by 70 ~ 80%, leading to clean and high quality transfer of thin-film electronic devices. Water-assisted subcritical debonding is applicable for a range of metal-SiO2 interfaces, enabling the peel-and-stick process as a general and tunable method for fabricating flexible/transparent thin-film electronic devices.

  3. Effects of four different drying methods on the carotenoid composition and antioxidant capacity of dried Gac peel.

    PubMed

    Chuyen, Hoang V; Roach, Paul D; Golding, John B; Parks, Sophie E; Nguyen, Minh H

    2017-03-01

    Gac fruit (Momordica cochinchinensis Spreng.) is a rich source of carotenoids for the manufacture of powder, oil and capsules for food, cosmetic and pharmaceutical uses. Currently, only the aril of the Gac fruit is processed and the peel, similar to the other components, is discarded, although it contains high level of carotenoids, which could be extracted for commercial use. In the present study, four different drying methods (hot-air, vacuum, heat pump and freeze drying), different temperatures and drying times were investigated for producing dried Gac peel suitable for carotenoid extraction. The drying methods and drying temperatures significantly affected the drying time, carotenoid content and antioxidant capacity of the dried Gac peel. Among the investigated drying methods, hot-air drying at 80  o C and vacuum drying at 50  o C produced dried Gac peel that exhibited the highest retention of carotenoids and the strongest antioxidant capacity. Hot-air drying at 80  o C and vacuum drying at 50  o C are recommended for the drying of Gac peel. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  4. Delayed response to cold stress is characterized by successive metabolic shifts culminating in apple fruit peel necrosis.

    PubMed

    Gapper, Nigel E; Hertog, Maarten L A T M; Lee, Jinwook; Buchanan, David A; Leisso, Rachel S; Fei, Zhangjun; Qu, Guiqin; Giovannoni, James J; Johnston, Jason W; Schaffer, Robert J; Nicolaï, Bart M; Mattheis, James P; Watkins, Christopher B; Rudell, David R

    2017-04-21

    Superficial scald is a physiological disorder of apple fruit characterized by sunken, necrotic lesions appearing after prolonged cold storage, although initial injury occurs much earlier in the storage period. To determine the degree to which the transition to cell death is an active process and specific metabolism involved, untargeted metabolic and transcriptomic profiling was used to follow metabolism of peel tissue over 180 d of cold storage. The metabolome and transcriptome of peel destined to develop scald began to diverge from peel where scald was controlled using antioxidant (diphenylamine; DPA) or rendered insensitive to ethylene using 1-methylcyclopropene (1-MCP) beginning between 30 and 60 days of storage. Overall metabolic and transcriptomic shifts, representing multiple pathways and processes, occurred alongside α-farnesene oxidation and, later, methanol production alongside symptom development. Results indicate this form of peel necrosis is a product of an active metabolic transition involving multiple pathways triggered by chilling temperatures at cold storage inception rather than physical injury. Among multiple other pathways, enhanced methanol and methyl ester levels alongside upregulated pectin methylesterases are unique to peel that is developing scald symptoms similar to injury resulting from mechanical stress and herbivory in other plants.

  5. Effect of aeration rate and waste load on evolution of volatile fatty acids and waste stabilization during thermophilic aerobic digestion of a model high strength agricultural waste.

    PubMed

    Ugwuanyi, J Obeta; Harvey, L M; McNeil, B

    2005-04-01

    Thermophilic aerobic digestion (TAD) is a relatively new, dynamic and versatile low technology for the economic processing of high strength waste slurries. Waste so treated may be safely disposed of or reused. In this work a model high strength agricultural waste, potato peel, was subjected to TAD to study the effects of oxygen supply at 0.1, 0.25, 0.5 and 1.0 vvm (volume air per volume slurry per minute) under batch conditions at 55 degrees C for 156 h on the process. Process pH was controlled at 7.0 or left unregulated. Effects of waste load, as soluble chemical oxygen demand (COD), on TAD were studied at 4.0, 8.0, 12.0 and 16.0 gl(-1) (soluble COD) at pH 7.0, 0.5 vvm and 55 degrees C. Efficiency of treatment, as degradation of total solids, total suspended solids and soluble solid, as well as soluble COD significantly increased with aeration rate, while acetate production increased as the aeration rate decreased or waste load increased, signifying deterioration in treatment. Negligible acetate, and no other acids were produced at 1.0 vvm. Production of propionate and other acids increased after acetate concentration had started to decrease and, during unregulated reactions coincided with the drop in the pH of the slurry. Acetate production was more closely associated with periods of oxygen limitation than were other acids. Reduction in oxygen availability led to deterioration in treatment efficiency as did increase in waste load. These variables may be manipulated to control treated waste quality.

  6. Influence of apple and citrus pectins, processed mango peels, a phenolic mango peel extract, and gallic Acid as potential feed supplements on in vitro total gas production and rumen methanogenesis.

    PubMed

    Geerkens, Christian Hubert; Schweiggert, Ralf Martin; Steingass, Herbert; Boguhn, Jeannette; Rodehutscord, Markus; Carle, Reinhold

    2013-06-19

    Several food processing byproducts were assessed as potential feed and feed supplements. Since their chemical composition revealed a high nutritional potential for ruminants, the Hohenheim in vitro gas test was used to investigate total gas, methane, and volatile fatty acid production as well as protozoal numbers after ruminal digestion of different substrate levels. Processing byproducts used were low- and high-esterified citrus and apple pectins, integral mango peels, and depectinized mango peels. In addition, the effect of a phenolic mango peel extract and pure gallic acid was investigated. The highest decrease in methane production (19%) was achieved by supplementing high levels of low-esterified citrus pectin to the hay-based diet. Interestingly, total gas production was not affected at the same time. Showing valuable nutritional potential, all byproducts exhibited, e.g., high metabolizable energy (11.9-12.8 MJ/kg DM). In conclusion, all byproducts, particularly low-esterified citrus pectin, revealed promising potential as feed and feed supplements.

  7. Development of methods for skin barrier peeling tests.

    PubMed

    Omura, Yuko; Kazuharu, Seki; Kenji, Oishi

    2006-01-01

    We sought to develop a more effective method to evaluate the adhesive properties of skin barriers. The experimental design used was based on 3 principles: partial control, randomization, and repetition. Using these principles, the 180-degree peeling tests were conducted as specified in a standardized methodology (JIS Z0297) to the extent possible. However, the use of a stainless steel plate as a proxy for skin barrier application may result in the stretching and breaking of the skin barrier, making it impossible to obtain suitable measurements. Tests were conducted in constant temperature/ humidity chambers using a Tensilon Automatic Elongation Tester, where a sample was fixed on the side of a sample immobilization device, a sturdy metal (aluminum) box from which the air in the box was drawn off with a vacuum pump. A fluorocarbon polymer film was applied to the adhesive surface of a sample skin barrier. The film was peeled off in the volte-face (180-degree) direction in order to measure adhesive strengths. The films exhibit such properties as (a) ease of removal from the adhesive surface, (b) no resistance to a 180-degree fold back due to the thinness and flexibility of the material, and (c) tolerance of elongation. The adhesive properties of skin barriers were measured by peeling the fluorocarbon polymers in a 180-degree direction. Twelve specimen skin barrier products were selected for measurement, providing results with satisfactory reproducibility. Results based on the conventional stainless steel plate-based testing method acted as a control. The newly developed testing method enables chronological measurement results for skin barriers applied to fluorocarbon polymer films after 24 hours, 48 hours, and longer period.

  8. Antioxidant activity and protective effect of banana peel against oxidative hemolysis of human erythrocyte at different stages of ripening.

    PubMed

    Sundaram, Shanthy; Anjum, Shadma; Dwivedi, Priyanka; Rai, Gyanendra Kumar

    2011-08-01

    Phytochemicals such as polyphenols and carotenoids are gaining importance because of their contribution to human health and their multiple biological effects such as antioxidant, antimutagenic, anticarcinogenic, and cytoprotective activities and their therapeutic properties. Banana peel is a major by-product in pulp industry and it contains various bioactive compounds like polyphenols, carotenoids, and others. In the present study, effect of ripening, solvent polarity on the content of bioactive compounds of crude banana peel and the protective effect of peel extracts of unripe, ripe, and leaky ripe banana fruit on hydrogen peroxide-induced hemolysis and their antioxidant capacity were investigated. Banana (Musa paradisica) peel at different stages of ripening (unripe, ripe, leaky ripe) were treated with 70% acetone, which were partitioned in order of polarity with water, ethyl acetate, chloroform (CHCl₃), and hexane sequentially. The antioxidant activity of the samples was evaluated by the red cell hemolysis assay, free radical scavenging (1,1-diphenyl-2-picrylhydrazyl free radical elimination) and superoxide dismutase activities. The Folin-Ciocalteu's reagent assay was used to estimate the phenolic content of extracts. The findings of this investigation suggest that the unripe banana peel sample had higher antioxidant potency than ripe and leaky ripe. Further on fractionation, ethyl acetate and water soluble fractions of unripe peel displayed high antioxidant activity than CHCl₃ and hexane fraction, respectively. A positive correlation between free radical scavenging capacity and the content of phenolic compound were found in unripe, ripe, and leaky ripe stages of banana peel.

  9. Chemical composition and antioxidant and anti-inflammatory potential of peels and flesh from 10 different pear varieties (Pyrus spp.).

    PubMed

    Li, Xia; Wang, Tingting; Zhou, Bin; Gao, Wenyuan; Cao, Jingguo; Huang, Luqi

    2014-01-01

    This study was performed to compare the contents of total phenolics, total flavonoids, and total triterpenes between peel and flesh of ten different pear cultivars. The monomeric compounds were analyzed by HPLC, their antioxidant and anti-inflammatory activities were also measured. Peel and flesh from Yaguang, Hongpi, Qingpi and Guifei varieties contained relatively more total phenolic, total flavonoids and total triterpene, and showed stronger antioxidant and anti-inflammatory activities, while Lvbaoshi and Youran appeared to be weakest among them. All the chemical components found in the pear peel were approximately 6-20 times higher than those in the flesh of pear. For the monomeric compounds, arbutin, oleanolic acid, ursolic acid, chlorogenic acid, epicatechin, and rutin were the dominant components contained in the ten pear cultivars both in peel and in flesh. All of the analyses suggested that the peel of pear might be an excellent polyphenol and triterpenes source. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Investigation of fruit peel extracts as sources for compounds with antioxidant and antiproliferative activities against human cell lines.

    PubMed

    Khonkarn, Ruttiros; Okonogi, Siriporn; Ampasavate, Chadarat; Anuchapreeda, Songyot

    2010-01-01

    The aim of this study was to evaluate antioxidant activity and cytotoxicity against human cell lines of fruit peel extracts from rambutan, mangosteen and coconut. The highest antioxidant activity was found from rambutan peel crude extract where the highest radical scavenging capacity via ABTS assay was from its ethyl acetate fraction with a TEAC value of 23.0mM/mg and the highest ferric ion reduction activity via FRAP assay was from its methanol fraction with an EC value of 20.2mM/mg. Importantly, using both assays, these fractions had a higher antioxidant activity than butylated hydroxyl toluene and vitamin E. It was shown that the ethyl acetate fraction of rambutan peel had the highest polyphenolic content with a gallic acid equivalent of 2.3mg/mL. The results indicate that the polyphenolic compounds are responsible for the observed antioxidant activity of the extracts. Interestingly, the hexane fraction of coconut peel showed a potent cytotoxic effect on KB cell line by MTT assay (IC(50)=7.7 microg/mL), and no detectable cytotoxicity toward normal cells. We concluded that the ethyl acetate fraction of rambutan peel is a promising resource for potential novel antioxidant agents whereas the hexane fraction of coconut peel may contain novel anticancer compounds. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  11. Prospects of banana waste utilization in wastewater treatment: A review.

    PubMed

    Ahmad, Tanweer; Danish, Mohammed

    2018-01-15

    This review article explores utilization of banana waste (fruit peels, pseudo-stem, trunks, and leaves) as precursor materials to produce an adsorbent, and its application against environmental pollutants such as heavy metals, dyes, organic pollutants, pesticides, and various other gaseous pollutants. In recent past, quite a good number of research articles have been published on the utilization of low-cost adsorbents derived from biomass wastes. The literature survey on banana waste derived adsorbents shown that due to the abundance of banana waste worldwide, it also considered as low-cost adsorbents with promising future application against various environmental pollutants. Furthermore, raw banana biomass can be chemically modified to prepare efficient adsorbent as per requirement; chemical surface functional group modification may enhance the multiple uses of the adsorbent with industrial standard. It was evident from a literature survey that banana waste derived adsorbents have significant removal efficiency against various pollutants. Most of the published articles on banana waste derived adsorbents have been discussed critically, and the conclusion is drawn based on the results reported. Some results with poorly performed experiments were also discussed and pointed out their lacking in reporting. Based on literature survey, the future research prospect on banana wastes has a significant impact on upcoming research strategy. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma.

    PubMed

    Sarkar, Rashmi; Garg, Vijay; Bansal, Shivani; Sethi, Sumit; Gupta, Chitra

    2016-03-01

    Melasma is acquired symmetric hypermelanosis characterized by light-to-deep brown pigmentation over cheeks, forehead, upper lip, and nose. Treatment of this condition is difficult and associated with high recurrence rates. Chemical peels have become a popular modality in the treatment of melasma. To compare the therapeutic efficacy and tolerability of glycolic acid (35%) versus salicylic-mandelic (SM) acid (20% salicylic/10% mandelic acid) versus phytic combination peels in Indian patients with melasma. Ninety patients diagnosed with melasma were randomly assigned into 3 groups of 30 patients each. Group A received glycolic acid (GA-35%) peel, Group B received SM acid, and Group C received phytic combination peels. Each group was primed with 4% hydroquinone and 0.05% tretinoin cream for 4 weeks before treatment. Chemical peeling was done after every 14 days in all groups until 12 weeks. Clinical evaluation using melasma area and severity index (MASI) score and photography was recorded at every visit and follow-up was done until 20 weeks. There was a decrease in MASI score in all 3 groups but it was statistically significantly lower in Group A than Group C (p = .00), and it was also statistically significantly lower in Group B than Group C (p = .00) but there was no statistically significant difference between Groups A and B (p = .876). Objective response to treatment evaluated by reduction in MASI scoring after 12 weeks was 62.36% reduction in GA group, 60.98% reduction in SM group, and 44.71% in phytic acid group. It is concluded that GA (35%) and SM acid peels are both equally efficacious and a safe treatment modality for melasma in Indian skin, and are more effective than phytic acid peels. Salicylic-mandelic peels are better tolerated and more suitable for Indian skin.

  13. The pharmacokinetics and health benefits of orange peel compounds

    USDA-ARS?s Scientific Manuscript database

    Orange peel is a resource rich in phenolic antioxidants, including several classes of flavonoids and hydroxycinnamates. These compounds have been extensively studied for their biological actions particularly against chronic diseases in humans. Yet, full development of these materials as new, commerc...

  14. Effect of solvent addition sequence on lycopene extraction efficiency from membrane neutralized caustic peeled tomato waste.

    PubMed

    Phinney, David M; Frelka, John C; Cooperstone, Jessica L; Schwartz, Steven J; Heldman, Dennis R

    2017-01-15

    Lycopene is a high value nutraceutical and its isolation from waste streams is often desirable to maximize profits. This research investigated solvent addition order and composition on lycopene extraction efficiency from a commercial tomato waste stream (pH 12.5, solids ∼5%) that was neutralized using membrane filtration. Constant volume dilution (CVD) was used to desalinate the caustic salt to neutralize the waste. Acetone, ethanol and hexane were used as direct or blended additions. Extraction efficiency was defined as the amount of lycopene extracted divided by the total lycopene in the sample. The CVD operation reduced the active alkali of the waste from 0.66 to <0.01M and the moisture content of the pulp increased from 93% to 97% (wet basis), showing the removal of caustic salts from the waste. Extraction efficiency varied from 32.5% to 94.5%. This study demonstrates a lab scale feasibility to extract lycopene efficiently from tomato processing byproducts. Published by Elsevier Ltd.

  15. Recovery of biomolecules from food wastes--a review.

    PubMed

    Baiano, Antonietta

    2014-09-17

    Food wastes are produced by a variety of sources, ranging from agricultural operations to household consumption. About 38% occurs during food processing. At present, the European Union legislation encourages the exploitation of co-products. This valorisation can be achieved through the extraction of high-value components such as proteins, polysaccharides, fibres, flavour compounds, and phytochemicals, which can be re-used as nutritionally and pharmacologically functional ingredients. Extraction can proceed according to solid-liquid extraction, Soxhlet extraction, pressurized fluid extraction, supercritical fluid extraction, ultrasound-assisted extraction, microwave-assisted extraction, pulsed electric field extraction, and enzyme-assisted extraction. Nevertheless, these techniques cannot be used indiscriminately and their choice depends on the type of biomolecules and matrix, the scale processing (laboratory or industrial), the ratio between production costs and economic values of the compounds to be extracted. The vegetable wastes include trimmings, peelings, stems, seeds, shells, bran, residues remaining after extraction of oil, starch, sugar, and juice. The animal-derived wastes include wastes from bred animals, wastes from seafood, wastes from dairy processing. The recovered biomolecules and by-products can be used to produce functional foods or as adjuvants in food processing or in medicinal and pharmaceutical preparations. This work is an overview of the type and amounts of food wastes; food waste legislation; conventional and novel techniques suitable for extracting biomolecules; food, medicinal and pharmaceutical uses of the recovered biomolecules and by-products, and future trends in these areas.

  16. Comparison of the Effectiveness of Pars Plana Vitrectomy with and without Internal Limiting Membrane Peeling for Idiopathic Retinal Membrane Removal: A Meta-Analysis

    PubMed Central

    Liu, Hanhan; Zuo, Shanru; Ding, Chun; Dai, Xunzhang; Zhu, Xiaohua

    2015-01-01

    We conducted a meta-analysis of published retrospective studies and compared the effectiveness of pars plana vitrectomy with and without internal limiting membrane (ILM) peeling for idiopathic epiretinal membrane (IERM). The results revealed that patients in the IERM+ILM peeling group had better BCVA after surgery within 12 months than those in IERM peeling group. But patients in the IERM peeling group showed better BCVA in the 18th month. More retrospective studies or randomized controlled trials are required to investigate and compare the long-term effect of IERM removal with and without ILM peeling. PMID:26693348

  17. [Exposure to nitrogen dioxide and respiratory health at 2 years in the INMA-Valencia cohort].

    PubMed

    Gutiérrez Oyarce, Alejandra; Ferrero, Amparo; Estarlich, Marisa; Esplugues, Ana; Iñiguez, Carmen; Ballester, Ferran

    2017-07-25

    To analyze the association between exposure to nitrogen dioxide (NO 2 ) during pregnancy and the postnatal period up to the age of 2 years old and the incidence of respiratory problems in children from the INMA-Valencia cohort. The study population included 624 children from the INMA-Valencia cohort. Individual exposure to NO 2 was estimated in different environments outside the home during pregnancy and up to the age of 2 using empirical measurement and data from geo-statistical methods. Respiratory symptoms were obtained from a questionnaire applied at the age of two. The association between NO 2 exposure and respiratory symptoms was performed using multivariate logistic regression. The cumulative incidence was 16.3% for persistent cough, 34.9% for wheezing and 27.6% for lower respiratory tract infections. No association was found between respiratory symptoms and exposure to NO 2 in any of the children. However an association between NO 2 exposure and persistent cough was found at two years of life in the children with a parental history of allergy. NO 2 exposure would lead to persistent cough in children with a parental history of allergies. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  18. Protein complex prediction for large protein protein interaction networks with the Core&Peel method.

    PubMed

    Pellegrini, Marco; Baglioni, Miriam; Geraci, Filippo

    2016-11-08

    Biological networks play an increasingly important role in the exploration of functional modularity and cellular organization at a systemic level. Quite often the first tools used to analyze these networks are clustering algorithms. We concentrate here on the specific task of predicting protein complexes (PC) in large protein-protein interaction networks (PPIN). Currently, many state-of-the-art algorithms work well for networks of small or moderate size. However, their performance on much larger networks, which are becoming increasingly common in modern proteome-wise studies, needs to be re-assessed. We present a new fast algorithm for clustering large sparse networks: Core&Peel, which runs essentially in time and storage O(a(G)m+n) for a network G of n nodes and m arcs, where a(G) is the arboricity of G (which is roughly proportional to the maximum average degree of any induced subgraph in G). We evaluated Core&Peel on five PPI networks of large size and one of medium size from both yeast and homo sapiens, comparing its performance against those of ten state-of-the-art methods. We demonstrate that Core&Peel consistently outperforms the ten competitors in its ability to identify known protein complexes and in the functional coherence of its predictions. Our method is remarkably robust, being quite insensible to the injection of random interactions. Core&Peel is also empirically efficient attaining the second best running time over large networks among the tested algorithms. Our algorithm Core&Peel pushes forward the state-of the-art in PPIN clustering providing an algorithmic solution with polynomial running time that attains experimentally demonstrable good output quality and speed on challenging large real networks.

  19. Characterization of banana peel by scanning electron microscopy and FT-IR spectroscopy and its use for cadmium removal.

    PubMed

    Memon, Jamil R; Memon, Saima Q; Bhanger, M I; Memon, G Zuhra; El-Turki, A; Allen, Geoffrey C

    2008-10-15

    This study describes the use of banana peel, a commonly produced fruit waste, for the removal of Cd(II) from environmental and industrial wastewater. The banana peel was characterized by FT-IR and scanning electron microscopy (SEM) coupled with energy dispersive X-ray (EDX) analysis. The parameters pH, contact time, initial metal ion concentration and temperature were investigated and found to be rapid ( approximately 97% within 10 min). The Langmuir adsorption isotherm was used to describe partitioning behavior for the system at room temperature. The value of Q(L) was found to be (35.52 mg g(-1)) higher than the previously reported materials. The binding of metal ions was found to be pH-dependent with the optimal sorption occurring at pH 8. The retained species were eluted with 5 mL of 5 x 10(-3)M HNO(3) with the detection limit of 1.7 x 10(-3)mg L(-1). Kinetics of sorption followed the pseudo-first-order rate equation with the rate constant k, equal to 0.13+/-0.01 min(-1). Thermodynamic parameters such as Gibbs free energy at 303K (-7.41+/-0.13 kJ mol(-1)) and enthalpy (40.56+/-2.34 kJ mol(-1)) indicated the spontaneous and endothermic nature of the sorption process. The developed method was utilized for the removal of Cd(II) ions from environmental and industrial wastewater samples using flame atomic absorption spectrophotometer (FAAS).

  20. Banana peel reductant for leaching medium grade manganese ore in sulfuric acid solution

    NASA Astrophysics Data System (ADS)

    Aripin, H.; Joni, I. Made; Busaeri, Nundang; Usrah, Ifkar; Sudiana, I. Nyoman; Sabchevski, Svilen

    2017-03-01

    In this investigation, manganese has been produced from medium grade manganese ore from Karangnunggal mine (West Java, Indonesia). The effects of weighed amount of banana peels on the structural and leaching properties have been studied. The material's properties have been characterized on the basis of the experimental data obtained using X-ray fluorescence (XRF), X-ray diffraction (XRD), and Fourier transforms infrared (FTIR) spectroscopy. It has been found that an increase of the weighed amount of banana peels up to 4 g leads to an increase of the leaching efficiency of manganese from manganese ore. Above 4 g, however, the leaching efficiency does not change significantly. The analysis based on the interpretation of both XRD patterns and FTIR spectrum allows one to explain the increase in the leaching efficiencies of manganese by the reduction of MnO2 minerals and by the removal of hemicelluloses groups of banana peel in the samples.