Sample records for perfect positive correlation

  1. A perfect correlate does not a surrogate make

    PubMed Central

    Baker, Stuart G; Kramer, Barnett S

    2003-01-01

    Background There is common belief among some medical researchers that if a potential surrogate endpoint is highly correlated with a true endpoint, then a positive (or negative) difference in potential surrogate endpoints between randomization groups would imply a positive (or negative) difference in unobserved true endpoints between randomization groups. We investigate this belief when the potential surrogate and unobserved true endpoints are perfectly correlated within each randomization group. Methods We use a graphical approach. The vertical axis is the unobserved true endpoint and the horizontal axis is the potential surrogate endpoint. Perfect correlation within each randomization group implies that, for each randomization group, potential surrogate and true endpoints are related by a straight line. In this scenario the investigator does not know the slopes or intercepts. We consider a plausible example where the slope of the line is higher for the experimental group than for the control group. Results In our example with unknown lines, a decrease in mean potential surrogate endpoints from control to experimental groups corresponds to an increase in mean true endpoint from control to experimental groups. Thus the potential surrogate endpoints give the wrong inference. Similar results hold for binary potential surrogate and true outcomes (although the notion of correlation does not apply). The potential surrogate endpointwould give the correct inference if either (i) the unknown lines for the two group coincided, which means that the distribution of true endpoint conditional on potential surrogate endpoint does not depend on treatment group, which is called the Prentice Criterion or (ii) if one could accurately predict the lines based on data from prior studies. Conclusion Perfect correlation between potential surrogate and unobserved true outcomes within randomized groups does not guarantee correct inference based on a potential surrogate endpoint. Even in early phase trials, investigators should not base conclusions on potential surrogate endpoints in which the only validation is high correlation with the true endpoint within a group. PMID:12962545

  2. An Anatomic Study on Whether the Immature Patella is Centered on an Anteroposterior Radiograph.

    PubMed

    Kyriakedes, James C; Liu, Raymond W

    2017-03-01

    In the operating room, after first obtaining a proper lateral radiograph with the condyles superimposed, a 90-degree rotation of the intraoperative fluoroscopy unit does not always produce an anteroposterior (AP) image with the patella centered. The orthogonality of these 2 views has not been well determined in children. This study was comprised of a radiographic group (35 knees) and a cadaveric group (59 knees). Both cadaveric and clinical images were obtained by resting or positioning the femur with the posterior condyles overlapped, and then taking an orthogonal AP image. Centering of the patella was calculated and multiple regression analysis was performed to determine the relationship between patellar centering and age, sex, ethnicity, mechanical lateral distal femoral angle (mLDFA), medial proximal tibial angle (MPTA), and contralateral centering. Mean patellar centering, expressed as the lateral position of the patella with respect to the total condylar width, was 0.08±0.10 in the radiographic group and 0.06±0.03 in the cadaveric group. Positive (lateral) patellar centering in 1 knee had a statistically significant correlation with positive patellar centering in the contralateral knee in both the radiographs and the cadavers. In the radiographic group, there was a statistically significant correlation between femoral varus and valgus deformities and positive patellar centering. In the cadaveric group, there was a statistically significant correlation between tibial valgus and negative (medial) patellar centering. The patella in an immature knee is rarely perfectly centered on a true AP image, and is usually seated slightly laterally within the femoral condyles. Obtaining a true AP intraoperative radiograph is critical to analyzing and correcting valgus and varus deformities, and in the proper placement of implants. When addressing knee deformity one should consider obtaining an AP view orthogonal either to a perfect lateral of the knee or orthogonal to the flexion axis of the knee, particularly when evaluating distal femoral deformity.

  3. Ab initio DFT+U study of He atom incorporation into UO(2) crystals.

    PubMed

    Gryaznov, Denis; Heifets, Eugene; Kotomin, Eugene

    2009-09-07

    We present and discuss results of the density functional theory (DFT) for perfect UO(2) crystals with He atoms in octahedral interstitial positions therein. We have calculated basic bulk crystal properties and He incorporation energies into the low temperature anti-ferromagnetic UO(2) phase using several exchange-correlation functionals within the spin-polarized local density (LDA) and generalized gradient (GGA) approximations. In all DFT calculations we included the on-site correlation corrections using the Hubbard model (DFT+U approach). We analysed a potential crystalline symmetry reduction from tetragonal down to orthorhombic structure and confirmed the presence of the Jahn-Teller effect in a perfect UO(2). We discuss also the problem of a conducting electronic state arising when He is placed into a tetragonal antiferromagnetic phase of UO(2) commonly used in defect modelling. Consequently, we found a specific monoclinic lattice distortion which allowed us to restore the semiconducting state and properly estimate He incorporation energies. Unlike the bulk properties, the He incorporation energy strongly depends on several factors, including the supercell size, the use of spin polarization, the exchange-correlation functionals and on-site correlation corrections. We compare our results for the He incorporation with the previous shell model and ab initio DFT calculations.

  4. Statistical measures of Planck scale signal correlations in interferometers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hogan, Craig J.; Kwon, Ohkyung

    2015-06-22

    A model-independent statistical framework is presented to interpret data from systems where the mean time derivative of positional cross correlation between world lines, a measure of spreading in a quantum geometrical wave function, is measured with a precision smaller than the Planck time. The framework provides a general way to constrain possible departures from perfect independence of classical world lines, associated with Planck scale bounds on positional information. A parametrized candidate set of possible correlation functions is shown to be consistent with the known causal structure of the classical geometry measured by an apparatus, and the holographic scaling of informationmore » suggested by gravity. Frequency-domain power spectra are derived that can be compared with interferometer data. As a result, simple projections of sensitivity for specific experimental set-ups suggests that measurements will directly yield constraints on a universal time derivative of the correlation function, and thereby confirm or rule out a class of Planck scale departures from classical geometry.« less

  5. Orbital optimisation in the perfect pairing hierarchy: applications to full-valence calculations on linear polyacenes

    NASA Astrophysics Data System (ADS)

    Lehtola, Susi; Parkhill, John; Head-Gordon, Martin

    2018-03-01

    We describe the implementation of orbital optimisation for the models in the perfect pairing hierarchy. Orbital optimisation, which is generally necessary to obtain reliable results, is pursued at perfect pairing (PP) and perfect quadruples (PQ) levels of theory for applications on linear polyacenes, which are believed to exhibit strong correlation in the π space. While local minima and σ-π symmetry breaking solutions were found for PP orbitals, no such problems were encountered for PQ orbitals. The PQ orbitals are used for single-point calculations at PP, PQ and perfect hextuples (PH) levels of theory, both only in the π subspace, as well as in the full σπ valence space. It is numerically demonstrated that the inclusion of single excitations is necessary also when optimised orbitals are used. PH is found to yield good agreement with previously published density matrix renormalisation group data in the π space, capturing over 95% of the correlation energy. Full-valence calculations made possible by our novel, efficient code reveal that strong correlations are weaker when larger basis sets or active spaces are employed than in previous calculations. The largest full-valence PH calculations presented correspond to a (192e,192o) problem.

  6. "Whose perfection is it anyway?": a virtuous consideration of enhancement.

    PubMed

    Keenan, James F

    1999-08-01

    Discussions of genetic enhancements often imply deep suspicions about human desires to manipulate or enhance the course of our future. These unspoken assumptions about the arrogance of the quest for perfection are at odds with the normally hopeful resonancy we find in contemporary theology. The author argues that these fears, suspicions and accusations are misplaced. The problem lies not with the question of whether we should pursue perfection, but rather what perfection we are pursuing. The author argues that perfection, properly understood, has an enormously positive function in the Roman Catholic tradition. The author examines three sources: the Scriptures, the scholastic tradition, and ascetical theology. He examines contemporary criticisms of perfectionism and suggests that an adequate virtue theory keeps us from engaging perfectionism as such. The author then shows how a positive, responsible view of perfection is an asset to our discussion on enhancement technology.

  7. Linking parasite populations in hosts to parasite populations in space through Taylor's law and the negative binomial distribution

    PubMed Central

    Poulin, Robert; Lagrue, Clément

    2017-01-01

    The spatial distribution of individuals of any species is a basic concern of ecology. The spatial distribution of parasites matters to control and conservation of parasites that affect human and nonhuman populations. This paper develops a quantitative theory to predict the spatial distribution of parasites based on the distribution of parasites in hosts and the spatial distribution of hosts. Four models are tested against observations of metazoan hosts and their parasites in littoral zones of four lakes in Otago, New Zealand. These models differ in two dichotomous assumptions, constituting a 2 × 2 theoretical design. One assumption specifies whether the variance function of the number of parasites per host individual is described by Taylor's law (TL) or the negative binomial distribution (NBD). The other assumption specifies whether the numbers of parasite individuals within each host in a square meter of habitat are independent or perfectly correlated among host individuals. We find empirically that the variance–mean relationship of the numbers of parasites per square meter is very well described by TL but is not well described by NBD. Two models that posit perfect correlation of the parasite loads of hosts in a square meter of habitat approximate observations much better than two models that posit independence of parasite loads of hosts in a square meter, regardless of whether the variance–mean relationship of parasites per host individual obeys TL or NBD. We infer that high local interhost correlations in parasite load strongly influence the spatial distribution of parasites. Local hotspots could influence control and conservation of parasites. PMID:27994156

  8. A New Approach to Extract Forest Water Use Efficiency from Eddy Covariance Data

    NASA Astrophysics Data System (ADS)

    Scanlon, T. M.; Sulman, B. N.

    2016-12-01

    Determination of forest water use efficiency (WUE) from eddy covariance data typically involves the following steps: (a) estimating gross primary productivity (GPP) from direct measurements of net ecosystem exchange (NEE) by extrapolating nighttime ecosystem respiration (ER) to daytime conditions, and (b) assuming direct evaporation (E) is minimal several days after rainfall, meaning that direct measurements of evapotranspiration (ET) are identical to transpiration (T). Both of these steps could lead to errors in the estimation of forest WUE. Here, we present a theoretical approach for estimating WUE through the analysis of standard eddy covariance data, which circumvents these steps. Only five statistics are needed from the high-frequency time series to extract WUE: CO2 flux, water vapor flux, standard deviation in CO2 concentration, standard deviation in water vapor concentration, and the correlation coefficient between CO2 and water vapor concentration for each half-hour period. The approach is based on the assumption that stomatal fluxes (i.e. photosynthesis and transpiration) lead to perfectly negative correlations and non-stomatal fluxes (i.e. ecosystem respiration and direct evaporation) lead to perfectly positive correlations within the CO2 and water vapor high frequency time series measured above forest canopies. A mathematical framework is presented, followed by a proof of concept using eddy covariance data and leaf-level measurements of WUE.

  9. Theory of incommensurate magnetic correlations across the insulator-superconductor transition of underdoped La2-xSrxCuO4.

    PubMed

    Sushkov, Oleg P; Kotov, Valeri N

    2005-03-11

    The main feature in the elastic neutron scattering of La2-xSrxCuO4 is the existence of incommensurate peaks with positions that jump from 45 degrees to 0 degrees at 5% doping. We show that the spiral state of the t-t(')-t('')-J model with realistic parameters describes these data perfectly. We explain why in the insulator the peak is at 45 degrees while it switches to 0 degrees precisely at the insulator-metal transition. The calculated positions of the peaks are in agreement with the data in both phases.

  10. A synchronous game for binary constraint systems

    NASA Astrophysics Data System (ADS)

    Kim, Se-Jin; Paulsen, Vern; Schafhauser, Christopher

    2018-03-01

    Recently, Slofstra proved that the set of quantum correlations is not closed. We prove that the set of synchronous quantum correlations is not closed, which implies his result, by giving an example of a synchronous game that has a perfect quantum approximate strategy but no perfect quantum strategy. We also exhibit a graph for which the quantum independence number and the quantum approximate independence number are different. We prove new characterisations of synchronous quantum approximate correlations and synchronous quantum spatial correlations. We solve the synchronous approximation problem of Dykema and the second author, which yields a new equivalence of Connes' embedding problem in terms of synchronous correlations.

  11. Paradeisos: A perfect hashing algorithm for many-body eigenvalue problems

    NASA Astrophysics Data System (ADS)

    Jia, C. J.; Wang, Y.; Mendl, C. B.; Moritz, B.; Devereaux, T. P.

    2018-03-01

    We describe an essentially perfect hashing algorithm for calculating the position of an element in an ordered list, appropriate for the construction and manipulation of many-body Hamiltonian, sparse matrices. Each element of the list corresponds to an integer value whose binary representation reflects the occupation of single-particle basis states for each element in the many-body Hilbert space. The algorithm replaces conventional methods, such as binary search, for locating the elements of the ordered list, eliminating the need to store the integer representation for each element, without increasing the computational complexity. Combined with the "checkerboard" decomposition of the Hamiltonian matrix for distribution over parallel computing environments, this leads to a substantial savings in aggregate memory. While the algorithm can be applied broadly to many-body, correlated problems, we demonstrate its utility in reducing total memory consumption for a series of fermionic single-band Hubbard model calculations on small clusters with progressively larger Hilbert space dimension.

  12. The effect of on-line position correction on the dose distribution in focal radiotherapy for bladder cancer

    PubMed Central

    van Rooijen, Dominique C; van de Kamer, Jeroen B; Pool, René; Hulshof, Maarten CCM; Koning, Caro CE; Bel, Arjan

    2009-01-01

    Background The purpose of this study was to determine the dosimetric effect of on-line position correction for bladder tumor irradiation and to find methods to predict and handle this effect. Methods For 25 patients with unifocal bladder cancer intensity modulated radiotherapy (IMRT) with 5 beams was planned. The requirement for each plan was that 99% of the target volume received 95% of the prescribed dose. Tumor displacements from -2.0 cm to 2.0 cm in each dimension were simulated, using 0.5 cm increments, resulting in 729 simulations per patient. We assumed that on-line correction for the tumor was applied perfectly. We determined the correlation between the change in D99% and the change in path length, which is defined here as the distance from the skin to the isocenter for each beam. In addition the margin needed to avoid underdosage was determined and the probability that an underdosage occurs in a real treatment was calculated. Results Adjustments for tumor displacement with perfect on-line position correction resulted in an altered dose distribution. The altered fraction dose to the target varied from 91.9% to 100.4% of the prescribed dose. The mean D99% (± SD) was 95.8% ± 1.0%. There was a modest linear correlation between the difference in D99% and the change in path length of the beams after correction (R2 = 0.590). The median probability that a systematic underdosage occurs in a real treatment was 0.23% (range: 0 - 24.5%). A margin of 2 mm reduced that probability to < 0.001% in all patients. Conclusion On-line position correction does result in an altered target coverage, due to changes in average path length after position correction. An extra margin can be added to prevent underdosage. PMID:19775479

  13. Multipartite Einstein-Podolsky-Rosen steering and genuine tripartite entanglement with optical networks

    NASA Astrophysics Data System (ADS)

    Armstrong, Seiji; Wang, Meng; Teh, Run Yan; Gong, Qihuang; He, Qiongyi; Janousek, Jiri; Bachor, Hans-Albert; Reid, Margaret D.; Lam, Ping Koy

    2015-02-01

    Einstein, Podolsky and Rosen (EPR) pointed out in their famous paradox that two quantum-entangled particles can have perfectly correlated positions and momenta. Such correlations give evidence for the nonlocality of quantum mechanics and form the basis for quantum cryptography and teleportation. EPR steering is the nonlocality associated with the EPR paradox and has traditionally been investigated between only two parties. Using optical networks and efficient detection, we present experimental observations of multiparty EPR steering and of the genuine entanglement of three intense optical beams. We entangle the quadrature phase amplitudes of distinct fields, in analogy to the position-momentum entanglement of the original paradox. Our experiments complement tests of quantum mechanics that have entangled small systems or have demonstrated tripartite inseparability. Our methods establish principles for the development of multiparty quantum communication protocols with asymmetric observers, and can be extended to qubits, whether photonic, atomic, superconducting, or otherwise.

  14. How Does Ambiguity Affect Insurance Decisions

    DTIC Science & Technology

    1990-05-01

    actuarially fair value is C=$100. As with the actuaries, the underwriters charge higher premiums when either p and/or L is ambiguous. Even for the case where...probabilities they reacted by increasing the premium (i.e., reducing C) particularly for the perfectly correlated case. Thus when p=.01, the actuarially fair ... value is C=100. When losses are perfectly correlated and the actuary faces an ambiguous probability, the median value is C=9. The probability would

  15. Witnessing (Halted) Deconstruction: White Teachers' "Perfect Stranger" Position within Urban Indigenous Education

    ERIC Educational Resources Information Center

    Higgins, Marc; Madden, Brooke; Korteweg, Lisa

    2015-01-01

    This article extends upon Susan Dion's theory of the "perfect stranger" by exploring how this position is articulated and embodied by white teachers (N?=?67) involved in urban Indigenous education reform. On the lookout for deconstruction, we think with Derrida around the interrelated self/other and familiar/strange binaries that uphold…

  16. A tractable and accurate electronic structure method for static correlations: The perfect hextuples model

    NASA Astrophysics Data System (ADS)

    Parkhill, John A.; Head-Gordon, Martin

    2010-07-01

    We present the next stage in a hierarchy of local approximations to complete active space self-consistent field (CASSCF) model in an active space of one active orbital per active electron based on the valence orbital-optimized coupled-cluster (VOO-CC) formalism. Following the perfect pairing (PP) model, which is exact for a single electron pair and extensive, and the perfect quadruples (PQ) model, which is exact for two pairs, we introduce the perfect hextuples (PH) model, which is exact for three pairs. PH is an approximation to the VOO-CC method truncated at hextuples containing all correlations between three electron pairs. While VOO-CCDTQ56 requires computational effort scaling with the 14th power of molecular size, PH requires only sixth power effort. Our implementation also introduces some techniques which reduce the scaling to fifth order and has been applied to active spaces roughly twice the size of the CASSCF limit without any symmetry. Because PH explicitly correlates up to six electrons at a time, it can faithfully model the static correlations of molecules with up to triple bonds in a size-consistent fashion and for organic reactions usually reproduces CASSCF with chemical accuracy. The convergence of the PP, PQ, and PH hierarchy is demonstrated on a variety of examples including symmetry breaking in benzene, the Cope rearrangement, the Bergman reaction, and the dissociation of fluorine.

  17. Generating perfect fluid spheres in general relativity

    NASA Astrophysics Data System (ADS)

    Boonserm, Petarpa; Visser, Matt; Weinfurtner, Silke

    2005-06-01

    Ever since Karl Schwarzschild’s 1916 discovery of the spacetime geometry describing the interior of a particular idealized general relativistic star—a static spherically symmetric blob of fluid with position-independent density—the general relativity community has continued to devote considerable time and energy to understanding the general-relativistic static perfect fluid sphere. Over the last 90 years a tangle of specific perfect fluid spheres has been discovered, with most of these specific examples seemingly independent from each other. To bring some order to this collection, in this article we develop several new transformation theorems that map perfect fluid spheres into perfect fluid spheres. These transformation theorems sometimes lead to unexpected connections between previously known perfect fluid spheres, sometimes lead to new previously unknown perfect fluid spheres, and in general can be used to develop a systematic way of classifying the set of all perfect fluid spheres.

  18. Paradeisos: A perfect hashing algorithm for many-body eigenvalue problems

    DOE PAGES

    Jia, C. J.; Wang, Y.; Mendl, C. B.; ...

    2017-12-02

    Here, we describe an essentially perfect hashing algorithm for calculating the position of an element in an ordered list, appropriate for the construction and manipulation of many-body Hamiltonian, sparse matrices. Each element of the list corresponds to an integer value whose binary representation reflects the occupation of single-particle basis states for each element in the many-body Hilbert space. The algorithm replaces conventional methods, such as binary search, for locating the elements of the ordered list, eliminating the need to store the integer representation for each element, without increasing the computational complexity. Combined with the “checkerboard” decomposition of the Hamiltonian matrixmore » for distribution over parallel computing environments, this leads to a substantial savings in aggregate memory. While the algorithm can be applied broadly to many-body, correlated problems, we demonstrate its utility in reducing total memory consumption for a series of fermionic single-band Hubbard model calculations on small clusters with progressively larger Hilbert space dimension.« less

  19. Paradeisos: A perfect hashing algorithm for many-body eigenvalue problems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jia, C. J.; Wang, Y.; Mendl, C. B.

    Here, we describe an essentially perfect hashing algorithm for calculating the position of an element in an ordered list, appropriate for the construction and manipulation of many-body Hamiltonian, sparse matrices. Each element of the list corresponds to an integer value whose binary representation reflects the occupation of single-particle basis states for each element in the many-body Hilbert space. The algorithm replaces conventional methods, such as binary search, for locating the elements of the ordered list, eliminating the need to store the integer representation for each element, without increasing the computational complexity. Combined with the “checkerboard” decomposition of the Hamiltonian matrixmore » for distribution over parallel computing environments, this leads to a substantial savings in aggregate memory. While the algorithm can be applied broadly to many-body, correlated problems, we demonstrate its utility in reducing total memory consumption for a series of fermionic single-band Hubbard model calculations on small clusters with progressively larger Hilbert space dimension.« less

  20. Non-Parametric Collision Probability for Low-Velocity Encounters

    NASA Technical Reports Server (NTRS)

    Carpenter, J. Russell

    2007-01-01

    An implicit, but not necessarily obvious, assumption in all of the current techniques for assessing satellite collision probability is that the relative position uncertainty is perfectly correlated in time. If there is any mis-modeling of the dynamics in the propagation of the relative position error covariance matrix, time-wise de-correlation of the uncertainty will increase the probability of collision over a given time interval. The paper gives some examples that illustrate this point. This paper argues that, for the present, Monte Carlo analysis is the best available tool for handling low-velocity encounters, and suggests some techniques for addressing the issues just described. One proposal is for the use of a non-parametric technique that is widely used in actuarial and medical studies. The other suggestion is that accurate process noise models be used in the Monte Carlo trials to which the non-parametric estimate is applied. A further contribution of this paper is a description of how the time-wise decorrelation of uncertainty increases the probability of collision.

  1. No-signaling, perfect bipartite dichotomic correlations and local randomness

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seevinck, M. P.

    2011-03-28

    The no-signaling constraint on bi-partite correlations is reviewed. It is shown that in order to obtain non-trivial Bell-type inequalities that discern no-signaling correlations from more general ones, one must go beyond considering expectation values of products of observables only. A new set of nontrivial no-signaling inequalities is derived which have a remarkably close resemblance to the CHSH inequality, yet are fundamentally different. A set of inequalities by Roy and Singh and Avis et al., which is claimed to be useful for discerning no-signaling correlations, is shown to be trivially satisfied by any correlation whatsoever. Finally, using the set of newlymore » derived no-signaling inequalities a result with potential cryptographic consequences is proven: if different parties use identical devices, then, once they have perfect correlations at spacelike separation between dichotomic observables, they know that because of no-signaling the local marginals cannot but be completely random.« less

  2. Hanbury Brown and Twiss correlations of Cooper pairs in helical liquids

    NASA Astrophysics Data System (ADS)

    Choi, Mahn-Soo

    2014-01-01

    We propose a Hanbury Brown and Twiss (HBT) experiment of Cooper pairs on the edge channels of quantum spin Hall insulators. The helical edge channels provide a well-defined beam of Cooper pairs and perfect Andreev reflections from superconductors. This allows our setup to be identical in spirit to the original HBT experiment. Interestingly, the cross correlation is always negative and provides no hint of the bosonic nature of Cooper pairs. This counterintuitive result is attributed to the perfect Andreev reflection and the true beam splitter in the setup.

  3. Profiling and Quantification of Phenolics in Stevia rebaudiana Leaves.

    PubMed

    Karaköse, Hande; Müller, Anja; Kuhnert, Nikolai

    2015-10-21

    Stevia rebaudiana (Bertoni) is a plant from the Asteraceae family with significant economic value because of the steviol glycoside sweeteners in its leaves. Chlorogenic acids and flavonoid glycosides of S. rebaudiana from seven different botanical varieties cultivated over two years and harvested three times a year in eight European locations were profiled and quantified in a total of 166 samples. Compounds quantified include chlorogenic acids as well as flavonoid glycosides and aglycons. All phenolic concentration profiles show a perfect Gaussian distribution. Principal component analyses allow distinction between varieties of different geographical origin and distinction between different plant varieties. Although concentrations of all chlorogenic acids showed a positive correlation, no correlation was observed for flavonoid glycosides. Conclusions from these findings with respect to the biosynthesis and functional role of phenolics in S. rebaudiana are discussed.

  4. Staging laparoscopy improves treatment decision-making for advanced gastric cancer.

    PubMed

    Hu, Yan-Feng; Deng, Zhen-Wei; Liu, Hao; Mou, Ting-Yu; Chen, Tao; Lu, Xin; Wang, Da; Yu, Jiang; Li, Guo-Xin

    2016-02-07

    To evaluate the clinical value of staging laparoscopy in treatment decision-making for advanced gastric cancer (GC). Clinical data of 582 patients with advanced GC were retrospectively analyzed. All patients underwent staging laparoscopy. The strength of agreement between computed tomography (CT) stage, endoscopic ultrasound (EUS) stage, laparoscopic stage, and final stage were determined by weighted Kappa statistic (Kw). The number of patients with treatment decision-changes was counted. A χ(2) test was used to analyze the correlation between peritoneal metastasis or positive cytology and clinical characteristics. Among the 582 patients, the distributions of pathological T classifications were T2/3 (153, 26.3%), T4a (262, 45.0%), and T4b (167, 28.7%). Treatment plans for 211 (36.3%) patients were changed after staging laparoscopy was performed. Two (10.5%) of 19 patients in M1 regained the opportunity for potential radical resection by staging laparoscopy. Unnecessary laparotomy was avoided in 71 (12.2%) patients. The strength of agreement between preoperative T stage and final T stage was in almost perfect agreement (Kw = 0.838; 95% confidence interval (CI): 0.803-0.872; P < 0.05) for staging laparoscopy; compared with CT and EUS, which was in fair agreement. The strength of agreement between preoperative M stage and final M stage was in almost perfect agreement (Kw = 0.990; 95% CI: 0.977-1.000; P < 0.05) for staging laparoscopy; compared with CT, which was in slight agreement. Multivariate analysis revealed that tumor size (≥ 40 mm), depth of tumor invasion (T4b), and Borrmann type (III or IV) were significantly correlated with either peritoneal metastasis or positive cytology. The best performance in diagnosing P-positive was obtained when two or three risk factors existed. Staging laparoscopy can improve treatment decision-making for advanced GC and decrease unnecessary exploratory laparotomy.

  5. FY*A silencing by the GATA-motif variant FY*A(-69C) in a Caucasian family.

    PubMed

    Písačka, Martin; Marinov, Iuri; Králová, Miroslava; Králová, Jana; Kořánová, Michaela; Bohoněk, Miloš; Sood, Chhavi; Ochoa-Garay, Gorka

    2015-11-01

    The c.1-67C variant polymorphism in a GATA motif of the FY promoter is known to result in erythroid-specific FY silencing, that is, in Fy(a-) and Fy(b-) phenotypes. A Caucasian donor presented with the very rare Fy(a-b-) phenotype and was further investigated. Genomic DNA was analyzed by sequencing to identify the cause of the Fy(a-b-) phenotype. Samples were collected from some of his relatives to establish a correlation between the serology and genotyping results. Red blood cells were analyzed by gel column agglutination and flow cytometry. Genomic DNA was analyzed on genotyping microarrays, by DNA sequencing and by allele-specific PCR. In the donor, a single-nucleotide polymorphism T>C within the GATA motif was found at Position c.1-69 of the FY promoter and shown to occur in the FY*A allele. His genotype was found to be FY*A(-69C), FY*BW.01. In six FY*A/FY*B heterozygous members of the family, a perfect correlation was found between the presence vs. absence of the FY*A(-69C) variant allele and a Fy(a-) vs. Fy(a+) phenotype. The location of the c.1-69C polymorphism in a GATA motif whose disruption is known to result in a Fy null phenotype, together with the perfect correlation between the presence of the FY*A(-69C) allele and the Fy(a-) phenotype support a cause-effect relationship between the two. © 2015 AABB.

  6. Monitoring drug use among HIV/AIDS patients in Brazil: should we combine self-report and urinalysis?

    PubMed

    Malbergier, Andre; do Amaral, Ricardo A; Cardoso, Luciana R D; Castel, Saulo

    2012-12-01

    Illicit drug use in HIV-infected patients can be linked to impairment of physical and mental health, low health related quality of life, and suboptimal adherence to HIV treatment. This study aimed to evaluate the correlation of self report illicit drug use, urinalysis for cocaine and cannabis metabolites, and severity of dependence among HIV-infected patients on antiretroviral therapy (ART) in a treatment center in Brazil. Four hundred and thirty-eight outpatients of an HIV referral center were interviewed and assessed for drug use (lifetime, last year and last month). Urinalysis was performed to detect the presence of cocaine and cannabis metabolites in urine samples. Overall agreement between self report and urinalysis was almost 68% for cannabis and higher than 85% for cocaine. Positive urinalysis was significantly associated with more than once a week cannabis (p< .0001) and cocaine (p< .0001) use during the last-month. Severity of Dependence Scale (SDS) properly predicted positive cocaine urinalysis results (area under the curve [AUC] = .81, p = .0001). Frequency of cannabis and cocaine use, SDS score degree and positive urinalysis for both drugs were correlated. Our findings suggest that positive self-report is a reliable predictor of positive urine sample both for cannabis and cocaine, but since the agreement was not perfect, there is a role for urine drug screening in the care of patients with HIV-related conditions.

  7. Atmospheric scanning electron microscope for correlative microscopy.

    PubMed

    Morrison, Ian E G; Dennison, Clare L; Nishiyama, Hidetoshi; Suga, Mitsuo; Sato, Chikara; Yarwood, Andrew; O'Toole, Peter J

    2012-01-01

    The JEOL ClairScope is the first truly correlative scanning electron and optical microscope. An inverted scanning electron microscope (SEM) column allows electron images of wet samples to be obtained in ambient conditions in a biological culture dish, via a silicon nitride film window in the base. A standard inverted optical microscope positioned above the dish holder can be used to take reflected light and epifluorescence images of the same sample, under atmospheric conditions that permit biochemical modifications. For SEM, the open dish allows successive staining operations to be performed without moving the holder. The standard optical color camera used for fluorescence imaging can be exchanged for a high-sensitivity monochrome camera to detect low-intensity fluorescence signals, and also cathodoluminescence emission from nanophosphor particles. If these particles are applied to the sample at a suitable density, they can greatly assist the task of perfecting the correlation between the optical and electron images. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. A possibility of parallel and anti-parallel diffraction measurements on neu- tron diffractometer employing bent perfect crystal monochromator at the monochromatic focusing condition

    NASA Astrophysics Data System (ADS)

    Choi, Yong Nam; Kim, Shin Ae; Kim, Sung Kyu; Kim, Sung Baek; Lee, Chang-Hee; Mikula, Pavel

    2004-07-01

    In a conventional diffractometer having single monochromator, only one position, parallel position, is used for the diffraction experiment (i.e. detection) because the resolution property of the other one, anti-parallel position, is very poor. However, a bent perfect crystal (BPC) monochromator at monochromatic focusing condition can provide a quite flat and equal resolution property at both parallel and anti-parallel positions and thus one can have a chance to use both sides for the diffraction experiment. From the data of the FWHM and the Delta d/d measured on three diffraction geometries (symmetric, asymmetric compression and asymmetric expansion), we can conclude that the simultaneous diffraction measurement in both parallel and anti-parallel positions can be achieved.

  9. Assessment of the effect of pelvic floor exercises on pelvic floor muscle strength using ultrasonography in patients with urinary incontinence: a prospective randomized controlled trial

    PubMed Central

    Tosun, Ozge Celiker; Solmaz, Ulas; Ekin, Atalay; Tosun, Gokhan; Gezer, Cenk; Ergenoglu, Ahmet Mete; Yeniel, Ahmet Ozgur; Mat, Emre; Malkoc, Mehtap; Askar, Niyazi

    2016-01-01

    [Purpose] The aim of this study was to evaluate whether the effect of pelvic floor exercises on pelvic floor muscle strength could be detected via ultrasonography in patients with urinary incontinence. [Subjects and Methods] Of 282 incontinent patients, 116 participated in the study and were randomly divided into a pelvic floor muscle training (n=65) group or control group (n=51). The pelvic floor muscle training group was given pelvic floor exercise training for 12 weeks. Both groups were evaluated at the beginning of the study and after 12 weeks. Abdominal ultrasonography measurements in transverse and longitudinal planes, the PERFECT scheme, perineometric evaluation, the stop test, the stress test, and the pad test were used to assess pelvic floor muscle strength in all cases. [Results] After training, the PERFECT, perineometry and transabdominal ultrasonography measurements were found to be significantly improved, and the stop test and pad test results were significantly decreased in the pelvic floor muscle training group, whereas no difference was observed in the control group. There was a positive correlation between the PERFECT force measurement scale and ultrasonography force measurement scale before and after the intervention in the control and pelvic floor muscle training groups (r=0.632 and r=0.642, respectively). [Conclusion] Ultrasonography can be used as a noninvasive method to identify the change in pelvic floor muscle strength with exercise training. PMID:27065519

  10. Dynamic screening in a two-species asymmetric exclusion process

    NASA Astrophysics Data System (ADS)

    Kim, Kyung Hyuk; den Nijs, Marcel

    2007-08-01

    The dynamic scaling properties of the one-dimensional Burgers equation are expected to change with the inclusion of additional conserved degrees of freedom. We study this by means of one-dimensional (1D) driven lattice gas models that conserve both mass and momentum. The most elementary version of this is the Arndt-Heinzel-Rittenberg (AHR) process, which is usually presented as a two-species diffusion process, with particles of opposite charge hopping in opposite directions and with a variable passing probability. From the hydrodynamics perspective this can be viewed as two coupled Burgers equations, with the number of positive and negative momentum quanta individually conserved. We determine the dynamic scaling dimension of the AHR process from the time evolution of the two-point correlation functions, and find numerically that the dynamic critical exponent is consistent with simple Kardar-Parisi-Zhang- (KPZ) type scaling. We establish that this is the result of perfect screening of fluctuations in the stationary state. The two-point correlations decay exponentially in our simulations and in such a manner that in terms of quasiparticles, fluctuations fully screen each other at coarse grained length scales. We prove this screening rigorously using the analytic matrix product structure of the stationary state. The proof suggests the existence of a topological invariant. The process remains in the KPZ universality class but only in the sense of a factorization, as (KPZ)2 . The two Burgers equations decouple at large length scales due to the perfect screening.

  11. Disorder in Protein Crystals.

    NASA Astrophysics Data System (ADS)

    Clarage, James Braun, II

    1990-01-01

    Methods have been developed for analyzing the diffuse x-ray scattering in the halos about a crystal's Bragg reflections as a means of determining correlations in atomic displacements in protein crystals. The diffuse intensity distribution for rhombohedral insulin, tetragonal lysozyme, and triclinic lysozyme crystals was best simulated in terms of exponential displacement correlation functions. About 90% of the disorder can be accounted for by internal movements correlated with a decay distance of about 6A; the remaining 10% corresponds to intermolecular movements that decay in a distance the order of size of the protein molecule. The results demonstrate that protein crystals fit into neither the Einstein nor the Debye paradigms for thermally fluctuating crystalline solids. Unlike the Einstein model, there are correlations in the atomic displacements, but these correlations decay more steeply with distance than predicted by the Debye-Waller model for an elastic solid. The observed displacement correlations are liquid -like in the sense that they decay exponentially with the distance between atoms, just as positional correlations in a liquid. This liquid-like disorder is similar to the disorder observed in 2-D crystals of polystyrene latex spheres, and similar systems where repulsive interactions dominate; hence, these colloidal crystals appear to provide a better analogy for the dynamics of protein crystals than perfectly elastic lattices.

  12. Software for Verifying Image-Correlation Tie Points

    NASA Technical Reports Server (NTRS)

    Klimeck, Gerhard; Yagi, Gary

    2008-01-01

    A computer program enables assessment of the quality of tie points in the image-correlation processes of the software described in the immediately preceding article. Tie points are computed in mappings between corresponding pixels in the left and right images of a stereoscopic pair. The mappings are sometimes not perfect because image data can be noisy and parallax can cause some points to appear in one image but not the other. The present computer program relies on the availability of a left- right correlation map in addition to the usual right left correlation map. The additional map must be generated, which doubles the processing time. Such increased time can now be afforded in the data-processing pipeline, since the time for map generation is now reduced from about 60 to 3 minutes by the parallelization discussed in the previous article. Parallel cluster processing time, therefore, enabled this better science result. The first mapping is typically from a point (denoted by coordinates x,y) in the left image to a point (x',y') in the right image. The second mapping is from (x',y') in the right image to some point (x",y") in the left image. If (x,y) and(x",y") are identical, then the mapping is considered perfect. The perfect-match criterion can be relaxed by introducing an error window that admits of round-off error and a small amount of noise. The mapping procedure can be repeated until all points in each image not connected to points in the other image are eliminated, so that what remains are verified correlation data.

  13. Laparoscopic insertion of artificial periprostatic urinary sphincter.

    PubMed

    Gamé, Xavier; Bram, Raphael; Abu Anz, Sami; Doumerc, Nicolas; Guillotreau, Julien; Malavaud, Bernard; Rischmann, Pascal

    2009-02-01

    The objective of this case report is to describe the laparoscopic insertion of an artificial periprostatic urinary sphincter. We report the case of a paraplegic patient in whom an artificial urinary sphincter was inserted in a periprostatic position by way of laparoscopy to treat stress urinary incontinence. In addition to laparoscopy being minimally invasive, its advantages include the excellent quality of retroprostatic dissection and the perfect visualization it gives at the level of cuff positioning with respect to the anatomic landmarks. It is more appropriate to be able to cleave the interprostatorectal space to ensure passage of the cuff under perfectly safe conditions.

  14. Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays

    PubMed Central

    2011-01-01

    Introduction The human epidermal growth factor receptor 2 (HER2) is an established biomarker for management of patients with breast cancer. While conventional testing of HER2 protein expression is based on semi-quantitative visual scoring of the immunohistochemistry (IHC) result, efforts to reduce inter-observer variation and to produce continuous estimates of the IHC data are potentiated by digital image analysis technologies. Methods HER2 IHC was performed on the tissue microarrays (TMAs) of 195 patients with an early ductal carcinoma of the breast. Digital images of the IHC slides were obtained by Aperio ScanScope GL Slide Scanner. Membrane connectivity algorithm (HER2-CONNECT™, Visiopharm) was used for digital image analysis (DA). A pathologist evaluated the images on the screen twice (visual evaluations: VE1 and VE2). HER2 fluorescence in situ hybridization (FISH) was performed on the corresponding sections of the TMAs. The agreement between the IHC HER2 scores, obtained by VE1, VE2, and DA was tested for individual TMA spots and patient's maximum TMA spot values (VE1max, VE2max, DAmax). The latter were compared with the FISH data. Correlation of the continuous variable of the membrane connectivity estimate with the FISH data was tested. Results The pathologist intra-observer agreement (VE1 and VE2) on HER2 IHC score was almost perfect: kappa 0.91 (by spot) and 0.88 (by patient). The agreement between visual evaluation and digital image analysis was almost perfect at the spot level (kappa 0.86 and 0.87, with VE1 and VE2 respectively) and at the patient level (kappa 0.80 and 0.86, with VE1max and VE2max, respectively). The DA was more accurate than VE in detection of FISH-positive patients by recruiting 3 or 2 additional FISH-positive patients to the IHC score 2+ category from the IHC 0/1+ category by VE1max or VE2max, respectively. The DA continuous variable of the membrane connectivity correlated with the FISH data (HER2 and CEP17 copy numbers, and HER2/CEP17 ratio). Conclusion HER2 IHC digital image analysis based on membrane connectivity estimate was in almost perfect agreement with the visual evaluation of the pathologist and more accurate in detection of HER2 FISH-positive patients. Most immediate benefit of integrating the DA algorithm into the routine pathology HER2 testing may be obtained by alerting/reassuring pathologists of potentially misinterpreted IHC 0/1+ versus 2+ cases. PMID:21943197

  15. Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays.

    PubMed

    Laurinaviciene, Aida; Dasevicius, Darius; Ostapenko, Valerijus; Jarmalaite, Sonata; Lazutka, Juozas; Laurinavicius, Arvydas

    2011-09-23

    The human epidermal growth factor receptor 2 (HER2) is an established biomarker for management of patients with breast cancer. While conventional testing of HER2 protein expression is based on semi-quantitative visual scoring of the immunohistochemistry (IHC) result, efforts to reduce inter-observer variation and to produce continuous estimates of the IHC data are potentiated by digital image analysis technologies. HER2 IHC was performed on the tissue microarrays (TMAs) of 195 patients with an early ductal carcinoma of the breast. Digital images of the IHC slides were obtained by Aperio ScanScope GL Slide Scanner. Membrane connectivity algorithm (HER2-CONNECT, Visiopharm) was used for digital image analysis (DA). A pathologist evaluated the images on the screen twice (visual evaluations: VE1 and VE2). HER2 fluorescence in situ hybridization (FISH) was performed on the corresponding sections of the TMAs. The agreement between the IHC HER2 scores, obtained by VE1, VE2, and DA was tested for individual TMA spots and patient's maximum TMA spot values (VE1max, VE2max, DAmax). The latter were compared with the FISH data. Correlation of the continuous variable of the membrane connectivity estimate with the FISH data was tested. The pathologist intra-observer agreement (VE1 and VE2) on HER2 IHC score was almost perfect: kappa 0.91 (by spot) and 0.88 (by patient). The agreement between visual evaluation and digital image analysis was almost perfect at the spot level (kappa 0.86 and 0.87, with VE1 and VE2 respectively) and at the patient level (kappa 0.80 and 0.86, with VE1max and VE2max, respectively). The DA was more accurate than VE in detection of FISH-positive patients by recruiting 3 or 2 additional FISH-positive patients to the IHC score 2+ category from the IHC 0/1+ category by VE1max or VE2max, respectively. The DA continuous variable of the membrane connectivity correlated with the FISH data (HER2 and CEP17 copy numbers, and HER2/CEP17 ratio). HER2 IHC digital image analysis based on membrane connectivity estimate was in almost perfect agreement with the visual evaluation of the pathologist and more accurate in detection of HER2 FISH-positive patients. Most immediate benefit of integrating the DA algorithm into the routine pathology HER2 testing may be obtained by alerting/reassuring pathologists of potentially misinterpreted IHC 0/1+ versus 2+ cases.

  16. Correlated randomness: Some examples of exotic statistical physics

    NASA Astrophysics Data System (ADS)

    Stanley, H. Eugene

    2005-05-01

    One challenge of biology, medicine, and economics is that the systems treated by these sciences have no perfect metronome in time and no perfect spatial architecture -- crystalline or otherwise. Nonetheless, as if by magic, out of nothing but randomness one finds remarkably fine-tuned processes in time and remarkably fine-tuned structures in space. To understand this `miracle', one might consider placing aside the human tendency to see the universe as a machine. Instead, one might address the challenge of uncovering how, through randomness (albeit, as we shall see, strongly correlated randomness), one can arrive at many spatial and temporal patterns in biology, medicine, and economics. Inspired by principles developed by statistical physics over the past 50 years -- scale invariance and universality -- we review some recent applications of correlated randomness to fields that might startle Boltzmann if he were alive today.

  17. Measurable residual disease testing in acute myeloid leukaemia.

    PubMed

    Hourigan, C S; Gale, R P; Gormley, N J; Ossenkoppele, G J; Walter, R B

    2017-07-01

    There is considerable interest in developing techniques to detect and/or quantify remaining leukaemia cells termed measurable or, less precisely, minimal residual disease (MRD) in persons with acute myeloid leukaemia (AML) in complete remission defined by cytomorphological criteria. An important reason for AML MRD-testing is the possibility of estimating the likelihood (and timing) of leukaemia relapse. A perfect MRD-test would precisely quantify leukaemia cells biologically able and likely to cause leukaemia relapse within a defined interval. AML is genetically diverse and there is currently no uniform approach to detecting such cells. Several technologies focused on immune phenotype or cytogenetic and/or molecular abnormalities have been developed, each with advantages and disadvantages. Many studies report a positive MRD-test at diverse time points during AML therapy identifies persons with a higher risk of leukaemia relapse compared with those with a negative MRD-test even after adjusting for other prognostic and predictive variables. No MRD-test in AML has perfect sensitivity and specificity for relapse prediction at the cohort- or subject levels and there are substantial rates of false-positive and -negative tests. Despite these limitations, correlations between MRD-test results and relapse risk have generated interest in MRD-test result-directed therapy interventions. However, convincing proof that a specific intervention will reduce relapse risk in persons with a positive MRD-test is lacking and needs testing in randomized trials. Routine clinical use of MRD-testing requires further refinements and standardization/harmonization of assay platforms and results reporting. Such data are needed to determine whether results of MRD-testing can be used as a surrogate end point in AML therapy trials. This could make drug-testing more efficient and accelerate regulatory approvals. Although MRD-testing in AML has advanced substantially, much remains to be done.

  18. Sweet Spots and Door Stops

    ERIC Educational Resources Information Center

    Thompson, Michael; Tsui, Stella; Leung, Chi Fan

    2011-01-01

    A sweet spot is referred to in sport as the perfect place to strike a ball with a racquet or bat. It is the point of contact between bat and ball where maximum results can be produced with minimal effort from the hand of the player. Similar physics can be applied to the less inspiring examples of door stops; the perfect position of a door stop is…

  19. Components in Hemispheric Lateralization.

    ERIC Educational Resources Information Center

    Lynes, Sharon C. S. L.; And Others

    The fact that there is an imperfect correlation between the asymmetrical function of the two halves of the brain and handedness has been a source of puzzlement for many investigators. Many theories have been proposed to explain handedness and why handedness does not correlate perfectly with other measures of lateralization. To assess the…

  20. Ion Conduction in Perfectly Aligned Block Copolymer-Ionic Liquid Mixtures

    NASA Astrophysics Data System (ADS)

    Choi, Jae-Hong; Elabd, Yossef A.; Winey, Karen I.

    2011-03-01

    Our earlier work to correlate the transport measurements in diblock copolymer-ionic liquid mixtures was limited by our bulk samples that have only partial alignment. Here, thin films with perfect alignment of lamellar microdomains from mixtures of a poly(methyl methacrylate- b -styrene) diblock copolymer and an ionic liquid, 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, have been studied. The morphologies will be characterized by cross-sectional transmission electron microscopy. Ion conduction will be presented within and through the thin film.

  1. Implementation of generalized quantum measurements for unambiguous discrimination of multiple non-orthogonal coherent states.

    PubMed

    Becerra, F E; Fan, J; Migdall, A

    2013-01-01

    Generalized quantum measurements implemented to allow for measurement outcomes termed inconclusive can perform perfect discrimination of non-orthogonal states, a task which is impossible using only measurements with definitive outcomes. Here we demonstrate such generalized quantum measurements for unambiguous discrimination of four non-orthogonal coherent states and obtain their quantum mechanical description, the positive-operator valued measure. For practical realizations of this positive-operator valued measure, where noise and realistic imperfections prevent perfect unambiguous discrimination, we show that our experimental implementation outperforms any ideal standard-quantum-limited measurement performing the same non-ideal unambiguous state discrimination task for coherent states with low mean photon numbers.

  2. Is the Aquarius sea surface salinity variability representative?

    NASA Astrophysics Data System (ADS)

    Carton, J.; Grodsky, S.

    2016-12-01

    The leading mode of the Aquarius monthly anomalous sea surface salinity (SSS) is evaluated within the 50S-50N belt, where SSS retrieval accuracy is higher. This mode accounts for about 18% of the variance and resembles a pattern of the ENSO-induced anomalous rainfall. The leading mode of SSS variability deducted from a longer JAMSTEC analysis also accounts for about 17% of the variance and has very similar spatial pattern and almost a perfect correspondence of its temporal principal component to the SOI index. In that sense, the Aquarius SSS variability at low and middle latitudes is representative of SSS variability that may be obtained from longer records. This is explained by the fact that during the Aquarius period (2011-2015), the SOI index changed significantly from La Nina toward El Nino state, thus spanning a significant range of its characteristic variations. Multivariate EOF analysis of anomalous SSS and SST suggests that ENSO-induced shift in the tropical Pacific rainfall produces negatively correlated variability of temperature and salinity, which are expected if the anomalous surface flux (stronger rainfall coincident with less downward radiation) drives the system. But, anomalous SSS and SST are positively correlated in some areas including the northwestern Atlantic shelf (north of the Gulfstream) and the Pacific sector adjusting to the California peninsula. This positive correlation is indicative of an advection driven regime that is analyzed separately.

  3. Volatile Profile of Raw Lamb Meat Stored at 4 ± 1 °C: The Potential of Specific Aldehyde Ratios as Indicators of Lamb Meat Quality

    PubMed Central

    2018-01-01

    The objectives of the present study were: (a) to evaluate the aroma evolution of raw lamb packaged in multi-layer coating film and stored at 4 ± 1 °C, with respect to storage time and (b) to investigate whether specific aldehyde ratios could serve as markers of lamb meat freshness and degree of oxidation. Volatile compounds were determined using headspace solid phase microextraction coupled to gas chromatography/mass spectrometry. Results showed that the most dominant volatiles were 2,2,4,6,6-pentamethyl-heptane, hexanal, 1-octen-3-ol, 1-hexanol, carbon disulfide and p-cymene. Volatile compound content was increased during storage time. However, statistically significant differences were recorded only for hexanal, heptanal, and nonanal (p < 0.05). Additionally, the evolution of aldehydes during storage recorded a positive Pearson’s correlation (r) (p < 0.05), whereas hexanal to nonanal, heptanal to nonanal, octanal to nonanal ratios, along with the sum of aldehydes to nonanal ratio, were positively correlated (r = 0.83–1.00) with the degree of oxidation (mg malonic dialdehyde per kg of lamb meat). A perfect Pearson’s correlation (r = 1) was obtained for the ratio hexanal to nonanal. Therefore, this ratio is proposed as an indicator of lamb meat freshness and overall quality. PMID:29547528

  4. Cervical vertebrae maturation index estimates on cone beam CT: 3D reconstructions vs sagittal sections.

    PubMed

    Bonfim, Marco A E; Costa, André L F; Fuziy, Acácio; Ximenez, Michel E L; Cotrim-Ferreira, Flávio A; Ferreira-Santos, Rívea I

    2016-01-01

    The aim of this study was to evaluate the performance of CBCT three-dimensional (3D) reconstructions and sagittal sections for estimates of cervical vertebrae maturation index (CVMI). The sample consisted of 72 CBCT examinations from patients aged 8-16 years (45 females and 27 males) selected from the archives of two private clinics. Two calibrated observers (kappa scores: ≥0.901) interpreted the CBCT settings twice. Intra- and interobserver agreement for both imaging exhibition modes was analyzed by kappa statistics, which was also used to analyze the agreement between 3D reconstructions and sagittal sections. Correlations between cervical vertebrae maturation estimates and chronological age, as well as between the assessments by 3D reconstructions and sagittal sections, were analyzed using gamma Goodman-Kruskal coefficients (α = 0.05). The kappa scores evidenced almost perfect agreement between the first and second assessments of the cervical vertebrae by 3D reconstructions (0.933-0.983) and sagittal sections (0.983-1.000). Similarly, the agreement between 3D reconstructions and sagittal sections was almost perfect (kappa index: 0.983). In most divergent cases, the difference between 3D reconstructions and sagittal sections was one stage of CVMI. Strongly positive correlations (>0.8, p < 0.001) were found not only between chronological age and CVMI but also between the estimates by 3D reconstructions and sagittal sections (p < 0.001). Although CBCT imaging must not be used exclusively for this purpose, it may be suitable for skeletal maturity assessments.

  5. Cervical vertebrae maturation index estimates on cone beam CT: 3D reconstructions vs sagittal sections

    PubMed Central

    Bonfim, Marco A E; Costa, André L F; Ximenez, Michel E L; Cotrim-Ferreira, Flávio A; Ferreira-Santos, Rívea I

    2016-01-01

    Objectives: The aim of this study was to evaluate the performance of CBCT three-dimensional (3D) reconstructions and sagittal sections for estimates of cervical vertebrae maturation index (CVMI). Methods: The sample consisted of 72 CBCT examinations from patients aged 8–16 years (45 females and 27 males) selected from the archives of two private clinics. Two calibrated observers (kappa scores: ≥0.901) interpreted the CBCT settings twice. Intra- and interobserver agreement for both imaging exhibition modes was analyzed by kappa statistics, which was also used to analyze the agreement between 3D reconstructions and sagittal sections. Correlations between cervical vertebrae maturation estimates and chronological age, as well as between the assessments by 3D reconstructions and sagittal sections, were analyzed using gamma Goodman–Kruskal coefficients (α = 0.05). Results: The kappa scores evidenced almost perfect agreement between the first and second assessments of the cervical vertebrae by 3D reconstructions (0.933–0.983) and sagittal sections (0.983–1.000). Similarly, the agreement between 3D reconstructions and sagittal sections was almost perfect (kappa index: 0.983). In most divergent cases, the difference between 3D reconstructions and sagittal sections was one stage of CVMI. Strongly positive correlations (>0.8, p < 0.001) were found not only between chronological age and CVMI but also between the estimates by 3D reconstructions and sagittal sections (p < 0.001). Conclusions: Although CBCT imaging must not be used exclusively for this purpose, it may be suitable for skeletal maturity assessments. PMID:26509559

  6. Fracture size and transmissivity correlations: Implications for transport simulations in sparse three-dimensional discrete fracture networks following a truncated power law distribution of fracture size

    NASA Astrophysics Data System (ADS)

    Hyman, J.; Aldrich, G. A.; Viswanathan, H. S.; Makedonska, N.; Karra, S.

    2016-12-01

    We characterize how different fracture size-transmissivity relationships influence flow and transport simulations through sparse three-dimensional discrete fracture networks. Although it is generally accepted that there is a positive correlation between a fracture's size and its transmissivity/aperture, the functional form of that relationship remains a matter of debate. Relationships that assume perfect correlation, semi-correlation, and non-correlation between the two have been proposed. To study the impact that adopting one of these relationships has on transport properties, we generate multiple sparse fracture networks composed of circular fractures whose radii follow a truncated power law distribution. The distribution of transmissivities are selected so that the mean transmissivity of the fracture networks are the same and the distributions of aperture and transmissivity in models that include a stochastic term are also the same.We observe that adopting a correlation between a fracture size and its transmissivity leads to earlier breakthrough times and higher effective permeability when compared to networks where no correlation is used. While fracture network geometry plays the principal role in determining where transport occurs within the network, the relationship between size and transmissivity controls the flow speed. These observations indicate DFN modelers should be aware that breakthrough times and effective permeabilities can be strongly influenced by such a relationship in addition to fracture and network statistics.

  7. Possibility of perfect concealment by lossy conventional and lossy metamaterial cylindrical invisibility cloaks

    NASA Astrophysics Data System (ADS)

    Dehbashi, Reza; Shahabadi, Mahmoud

    2013-12-01

    The commonly used coordinate transformation for cylindrical cloaks is generalized. This transformation is utilized to determine an anisotropic inhomogeneous diagonal material tensors of a shell type cloak for various material types, i.e., double-positive (DPS: ɛ, μ > 0), double-negative (DNG: ɛ, μ < 0), ɛ-negative (ENG), and μ-negative (MNG). To obtain conditions of perfect cloaking for various material types, a rigorous analysis is performed. It is shown that perfect cloaking will be achieved for same type material for the cloak and its surrounding medium. Moreover, material losses are included in the analysis to demonstrate that perfect cloaking for lossy materials can be achieved for identical loss tangent of the cloak and its surrounding material. Sensitivity of the cloaking performance to losses for different material types is also investigated. The obtained analytical results are verified using a Finite-Element computational analysis.

  8. Response to a periodic stimulus in a perfect integrate-and-fire neuron model driven by colored noise.

    PubMed

    Mankin, Romi; Rekker, Astrid

    2016-12-01

    The output interspike interval statistics of a stochastic perfect integrate-and-fire neuron model driven by an additive exogenous periodic stimulus is considered. The effect of temporally correlated random activity of synaptic inputs is modeled by an additive symmetric dichotomous noise. Using a first-passage-time formulation, exact expressions for the output interspike interval density and for the serial correlation coefficient are derived in the nonsteady regime, and their dependence on input parameters (e.g., the noise correlation time and amplitude as well as the frequency of an input current) is analyzed. It is shown that an interplay of a periodic forcing and colored noise can cause a variety of nonequilibrium cooperation effects, such as sign reversals of the interspike interval correlations versus noise-switching rate as well as versus the frequency of periodic forcing, a power-law-like decay of oscillations of the serial correlation coefficients in the long-lag limit, amplification of the output signal modulation in the instantaneous firing rate of the neural response, etc. The features of spike statistics in the limits of slow and fast noises are also discussed.

  9. Response to a periodic stimulus in a perfect integrate-and-fire neuron model driven by colored noise

    NASA Astrophysics Data System (ADS)

    Mankin, Romi; Rekker, Astrid

    2016-12-01

    The output interspike interval statistics of a stochastic perfect integrate-and-fire neuron model driven by an additive exogenous periodic stimulus is considered. The effect of temporally correlated random activity of synaptic inputs is modeled by an additive symmetric dichotomous noise. Using a first-passage-time formulation, exact expressions for the output interspike interval density and for the serial correlation coefficient are derived in the nonsteady regime, and their dependence on input parameters (e.g., the noise correlation time and amplitude as well as the frequency of an input current) is analyzed. It is shown that an interplay of a periodic forcing and colored noise can cause a variety of nonequilibrium cooperation effects, such as sign reversals of the interspike interval correlations versus noise-switching rate as well as versus the frequency of periodic forcing, a power-law-like decay of oscillations of the serial correlation coefficients in the long-lag limit, amplification of the output signal modulation in the instantaneous firing rate of the neural response, etc. The features of spike statistics in the limits of slow and fast noises are also discussed.

  10. Detection by PCR of pathogenic protozoa in raw and drinkable water samples in Colombia.

    PubMed

    Triviño-Valencia, Jessica; Lora, Fabiana; Zuluaga, Juan David; Gomez-Marin, Jorge E

    2016-05-01

    We evaluated the presence of DNA of Giardia, Toxoplasma, and Cryptosporidium by PCR, and of Giardia and Cryptosporidium genera by immunofluorescence antibody test (IFAT), in water samples, before, during, and after plant treatment for drinkable water. We applied this method in 38 samples of 10 l of water taken from each of the water treatment steps and in 8 samples taken at home (only for Toxoplasma PCR) in Quindio region in Colombia. There were 8 positive samples for Cryptosporidium parvum (21 %), 4 for Cryptosporidium hominis (10.5 %), 27 for Toxoplasma gondii (58.6 %), 2 for Giardia duodenalis assemblage A (5.2 %), and 5 for G. duodenalis assemblage B (13.1 %). By IFAT, 23 % were positive for Giardia and 21 % for Cryptosporidium. An almost perfect agreement was found between IFAT and combined results of PCR, by Kappa composite proportion analysis. PCR positive samples were significantly more frequent in untreated raw water for C. parvum (p = 0.02). High mean of fecal coliforms, high pH values, and low mean of chlorine residuals were strongly correlated with PCR positivity for G. duodenalis assemblage B. High pH value was correlated with PCR positivity for C. parvum. Phylogenetic analysis of DNA sequences was possible, showing water and human clinical sequences for Toxoplasma within the same phylogenetic group for B1 repeated sequence. PCR assay is complementary to IFAT assay for monitoring of protozoa in raw and drinkable water, enabling species identification and to look for phylogenetic analysis in protozoa from human and environmental sources.

  11. Summing up the Euler [phi] Function

    ERIC Educational Resources Information Center

    Loomis, Paul; Plytage, Michael; Polhill, John

    2008-01-01

    The Euler [phi] function counts the number of positive integers less than and relatively prime to a positive integer n. Here we look at perfect totient numbers, number for which [phi](n) + [phi]([phi](n)) + [phi]([phi]([phi](n))) + ... + 1 = n.

  12. Comparison between overground and dynamometer manual wheelchair propulsion.

    PubMed

    Koontz, Alicia M; Worobey, Lynn A; Rice, Ian M; Collinger, Jennifer L; Boninger, Michael L

    2012-08-01

    Laboratory-based simulators afford many advantages for studying physiology and biomechanics; however, they may not perfectly mimic wheelchair propulsion over natural surfaces. The goal of this study was to compare kinetic and temporal parameters between propulsion overground on a tile surface and on a dynamometer. Twenty-four experienced manual wheelchair users propelled at a self-selected speed on smooth, level tile and a dynamometer while kinetic data were collected using an instrumented wheel. A Pearson correlation test was used to examine the relationship between propulsion variables obtained on the dynamometer and the overground condition. Ensemble resultant force and moment curves were compared using cross-correlation and qualitative analysis of curve shape. User biomechanics were correlated (R ranging from 0.41 to 0.83) between surfaces. Overall, findings suggest that although the dynamometer does not perfectly emulate overground propulsion, wheelchair users were consistent with the direction and amount of force applied, the time peak force was reached, push angle, and their stroke frequency between conditions.

  13. Comparison Between Overground and Dynamometer Manual Wheelchair Propulsion

    PubMed Central

    Worobey, Lynn A.; Rice, Ian M.; Collinger, Jennifer L.; Boninger, Michael L.

    2017-01-01

    Laboratory-based simulators afford many advantages for studying physiology and biomechanics; however, they may not perfectly mimic wheelchair propulsion over natural surfaces. The goal of this study was to compare kinetic and temporal parameters between propulsion overground on a tile surface and on a dynamometer. Twenty-four experienced manual wheelchair users propelled at a self-selected speed on smooth, level tile and a dynamometer while kinetic data were collected using an instrumented wheel. A Pearson correlation test was used to examine the relationship between propulsion variables obtained on the dynamometer and the overground condition. Ensemble resultant force and moment curves were compared using cross-correlation and qualitative analysis of curve shape. User biomechanics were correlated (R ranging from 0.41 to 0.83) between surfaces. Overall, findings suggest that although the dynamometer does not perfectly emulate overground propulsion, wheelchair users were consistent with the direction and amount of force applied, the time peak force was reached, push angle, and their stroke frequency between conditions. PMID:22085811

  14. Cross Validated Temperament Scale Validities Computed Using Profile Similarity Metrics

    DTIC Science & Technology

    2017-04-27

    true at both the item and the scale level. 6 Moreover, the correlation between conventional scores and distance scores for these types of scales...have a perfect negative correlation , r = -1.00. From this perspective, conventional and distance scores are completely redundant. Therefore, we argue... correlation between each respondent’s rating profile and the scale key: shape-scores = rx,k. 2. Rating elevation difference, which is computed as the

  15. The Perfect Glass Paradigm: Disordered Hyperuniform Glasses Down to Absolute Zero

    NASA Astrophysics Data System (ADS)

    Zhang, G.; Stillinger, F. H.; Torquato, S.

    2016-11-01

    Rapid cooling of liquids below a certain temperature range can result in a transition to glassy states. The traditional understanding of glasses includes their thermodynamic metastability with respect to crystals. However, here we present specific examples of interactions that eliminate the possibilities of crystalline and quasicrystalline phases, while creating mechanically stable amorphous glasses down to absolute zero temperature. We show that this can be accomplished by introducing a new ideal state of matter called a “perfect glass”. A perfect glass represents a soft-interaction analog of the maximally random jammed (MRJ) packings of hard particles. These latter states can be regarded as the epitome of a glass since they are out of equilibrium, maximally disordered, hyperuniform, mechanically rigid with infinite bulk and shear moduli, and can never crystallize due to configuration-space trapping. Our model perfect glass utilizes two-, three-, and four-body soft interactions while simultaneously retaining the salient attributes of the MRJ state. These models constitute a theoretical proof of concept for perfect glasses and broaden our fundamental understanding of glass physics. A novel feature of equilibrium systems of identical particles interacting with the perfect-glass potential at positive temperature is that they have a non-relativistic speed of sound that is infinite.

  16. The Perfect Glass Paradigm: Disordered Hyperuniform Glasses Down to Absolute Zero.

    PubMed

    Zhang, G; Stillinger, F H; Torquato, S

    2016-11-28

    Rapid cooling of liquids below a certain temperature range can result in a transition to glassy states. The traditional understanding of glasses includes their thermodynamic metastability with respect to crystals. However, here we present specific examples of interactions that eliminate the possibilities of crystalline and quasicrystalline phases, while creating mechanically stable amorphous glasses down to absolute zero temperature. We show that this can be accomplished by introducing a new ideal state of matter called a "perfect glass". A perfect glass represents a soft-interaction analog of the maximally random jammed (MRJ) packings of hard particles. These latter states can be regarded as the epitome of a glass since they are out of equilibrium, maximally disordered, hyperuniform, mechanically rigid with infinite bulk and shear moduli, and can never crystallize due to configuration-space trapping. Our model perfect glass utilizes two-, three-, and four-body soft interactions while simultaneously retaining the salient attributes of the MRJ state. These models constitute a theoretical proof of concept for perfect glasses and broaden our fundamental understanding of glass physics. A novel feature of equilibrium systems of identical particles interacting with the perfect-glass potential at positive temperature is that they have a non-relativistic speed of sound that is infinite.

  17. The Perfect Glass Paradigm: Disordered Hyperuniform Glasses Down to Absolute Zero

    PubMed Central

    Zhang, G.; Stillinger, F. H.; Torquato, S.

    2016-01-01

    Rapid cooling of liquids below a certain temperature range can result in a transition to glassy states. The traditional understanding of glasses includes their thermodynamic metastability with respect to crystals. However, here we present specific examples of interactions that eliminate the possibilities of crystalline and quasicrystalline phases, while creating mechanically stable amorphous glasses down to absolute zero temperature. We show that this can be accomplished by introducing a new ideal state of matter called a “perfect glass”. A perfect glass represents a soft-interaction analog of the maximally random jammed (MRJ) packings of hard particles. These latter states can be regarded as the epitome of a glass since they are out of equilibrium, maximally disordered, hyperuniform, mechanically rigid with infinite bulk and shear moduli, and can never crystallize due to configuration-space trapping. Our model perfect glass utilizes two-, three-, and four-body soft interactions while simultaneously retaining the salient attributes of the MRJ state. These models constitute a theoretical proof of concept for perfect glasses and broaden our fundamental understanding of glass physics. A novel feature of equilibrium systems of identical particles interacting with the perfect-glass potential at positive temperature is that they have a non-relativistic speed of sound that is infinite. PMID:27892452

  18. Perception without self-matching in conditional tag based cooperation.

    PubMed

    McAvity, David M; Bristow, Tristen; Bunker, Eric; Dreyer, Alex

    2013-09-21

    We consider a model for the evolution of cooperation in a population where individuals may have one of a number of different heritable and distinguishable markers or tags. Individuals interact with each of their neighbors on a square lattice by either cooperating by donating some benefit at a cost to themselves or defecting by doing nothing. The decision to cooperate or defect is contingent on each individual's perception of its interacting partner's tag. Unlike in other tag-based models individuals do not compare their own tag to that of their interaction partner. That is, there is no self-matching. When perception is perfect the cooperation rate is substantially higher than in the usual spatial prisoner's dilemma game when the cost of cooperation is high. The enhancement in cooperation is positively correlated with the number of different tags. The more diverse a population is the more cooperative it becomes. When individuals start with an inability to perceive tags the population evolves to a state where individuals gain at least partial perception. With some reproduction mechanisms perfect perception evolves, but with others the ability to perceive tags is imperfect. We find that perception of tags evolves to lower levels when the cost of cooperation is higher. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Evaluation of the Communication Between Arachnoid Cysts and Neighboring Cerebrospinal Fluid Spaces by T2W 3D-SPACE With Variant Flip-Angle Technique at 3 T.

    PubMed

    Algin, Oktay

    2018-05-21

    Phase-contrast cine magnetic resonance imaging (PC-MRI) is a widely used technique for determination of possible communication of arachnoid cysts (ACs). Three-dimensional (3D) sampling perfection with application-optimized contrasts using different flip-angle evolutions (3D-SPACE) technique is a relatively new method for 3D isotropic scanning of the entire cranium within a short time. In this research, the usage of the 3D-SPACE technique in differentiation of communicating or noncommunicating type ACs was evaluated. Thirty-five ACs in 34 patients were retrospectively examined. The 3D-SPACE, PC-MRI, and contrast material-enhanced cisternography (if present) images of the patients were analyzed. Each cyst was described according to cyst size/location, third ventricle diameter, Evans index, and presence of hydrocephalus. Communication was defined as absent (score 0), suspected (score 1), or present (score 2) on each sequence. Results of PC-MRI or cisternography (if available) examinations were used as criterion standard techniques to categorize all cysts as communicating or noncommunicating type. The results of 3D-SPACE were compared with criterion standard techniques. The comparisons between groups were performed using Mann-Whitney and Fisher exact tests. For demonstration of communication status of the cysts, criterion standard test results and 3D-SPACE findings were almost in perfect harmony (κ[95% confidence interval: 0.94]; P < 0.001). When evaluating the communicative properties, 3D-SPACE findings correlated with other final results at a rate of 97%. There is a positive correlation with third ventricular diameters and Evans index for all patients (r = 0.77, P < 0.001). For other analyzed variables, there is no significant difference or correlation between the groups. The 3D-SPACE technique is an easy, useful, and noninvasive alternative for the evaluation of morphology, topographical relationships, and communication status of ACs.

  20. Mixed group validation: a method to address the limitations of criterion group validation in research on malingering detection.

    PubMed

    Frederick, R I

    2000-01-01

    Mixed group validation (MGV) is offered as an alternative to criterion group validation (CGV) to estimate the true positive and false positive rates of tests and other diagnostic signs. CGV requires perfect confidence about each research participant's status with respect to the presence or absence of pathology. MGV determines diagnostic efficiencies based on group data; knowing an individual's status with respect to pathology is not required. MGV can use relatively weak indicators to validate better diagnostic signs, whereas CGV requires perfect diagnostic signs to avoid error in computing true positive and false positive rates. The process of MGV is explained, and a computer simulation demonstrates the soundness of the procedure. MGV of the Rey 15-Item Memory Test (Rey, 1958) for 723 pre-trial criminal defendants resulted in higher estimates of true positive rates and lower estimates of false positive rates as compared with prior research conducted with CGV. The author demonstrates how MGV addresses all the criticisms Rogers (1997b) outlined for differential prevalence designs in malingering detection research. Copyright 2000 John Wiley & Sons, Ltd.

  1. Higher dimensional strange quark matter solutions in self creation cosmology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Şen, R., E-mail: ramazansen-1991@hotmail.com; Aygün, S., E-mail: saygun@comu.edu.tr

    In this study, we have generalized the higher dimensional flat Friedmann-Robertson-Walker (FRW) universe solutions for a cloud of string with perfect fluid attached strange quark matter (SQM) in Self Creation Cosmology (SCC). We have obtained that the cloud of string with perfect fluid does not survive and the string tension density vanishes for this model. However, we get dark energy model for strange quark matter with positive density and negative pressure in self creation cosmology.

  2. The quadrant method measuring four points is as a reliable and accurate as the quadrant method in the evaluation after anatomical double-bundle ACL reconstruction.

    PubMed

    Mochizuki, Yuta; Kaneko, Takao; Kawahara, Keisuke; Toyoda, Shinya; Kono, Norihiko; Hada, Masaru; Ikegami, Hiroyasu; Musha, Yoshiro

    2017-11-20

    The quadrant method was described by Bernard et al. and it has been widely used for postoperative evaluation of anterior cruciate ligament (ACL) reconstruction. The purpose of this research is to further develop the quadrant method measuring four points, which we named four-point quadrant method, and to compare with the quadrant method. Three-dimensional computed tomography (3D-CT) analyses were performed in 25 patients who underwent double-bundle ACL reconstruction using the outside-in technique. The four points in this study's quadrant method were defined as point1-highest, point2-deepest, point3-lowest, and point4-shallowest, in femoral tunnel position. Value of depth and height in each point was measured. Antero-medial (AM) tunnel is (depth1, height2) and postero-lateral (PL) tunnel is (depth3, height4) in this four-point quadrant method. The 3D-CT images were evaluated independently by 2 orthopaedic surgeons. A second measurement was performed by both observers after a 4-week interval. Intra- and inter-observer reliability was calculated by means of intra-class correlation coefficient (ICC). Also, the accuracy of the method was evaluated against the quadrant method. Intra-observer reliability was almost perfect for both AM and PL tunnel (ICC > 0.81). Inter-observer reliability of AM tunnel was substantial (ICC > 0.61) and that of PL tunnel was almost perfect (ICC > 0.81). The AM tunnel position was 0.13% deep, 0.58% high and PL tunnel position was 0.01% shallow, 0.13% low compared to quadrant method. The four-point quadrant method was found to have high intra- and inter-observer reliability and accuracy. This method can evaluate the tunnel position regardless of the shape and morphology of the bone tunnel aperture for use of comparison and can provide measurement that can be compared with various reconstruction methods. The four-point quadrant method of this study is considered to have clinical relevance in that it is a detailed and accurate tool for evaluating femoral tunnel position after ACL reconstruction. Case series, Level IV.

  3. On doing two things at once: III. Confirmation of perfect timesharing when simultaneous tasks are ideomotor compatible.

    PubMed

    Greenwald, Anthony G

    2003-10-01

    A. G. Greenwald and H. G. Shulman (see record 1974-10326-001) found that 2 tasks characterized by ideomotor (IM) compatibility could be perfectly timeshared (i.e., performed simultaneously without mutual interference). The 2 tasks were pronouncing "A" or "B" in response to hearing those letter names, and making a manual left or right response to seeing a left- or right-positioned arrow. M.-C. Lien, R. W. Proctor, and P. A. Allen (2002) did not replicate Greenwald and Shulman's result, and concluded that their finding of perfect timesharing of 2 IM-compatible tasks might not be replicable. In the present research, Experiment 1 replicated Greenwald and Shulman's 1973 finding while also supporting the conclusion that Lien et al's nonreplication was due to their not instructing subjects to make 2 responses simultaneously in their timeshared task. Experiment 2 again replicated the perfect timesharing finding, using an alternative control procedure that mixed manual and vocal tasks in the same block. ((c) 2003 APA, all rights reserved)

  4. 78 FR 23601 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... liability under the option (i.e., the strike price). The Sub-Adviser will seek a correlation over time of 0... represent perfect correlation.\\12\\ \\12\\ While the Fund will not invest in traditional reverse convertible... the Fund. First, the commenter states that the name of the Fund is very descriptive and will not be...

  5. Synthesis of hover autopilots for rotary-wing VTOL aircraft

    NASA Technical Reports Server (NTRS)

    Hall, W. E.; Bryson, A. E., Jr.

    1972-01-01

    The practical situation is considered where imperfect information on only a few rotor and fuselage state variables is available. Filters are designed to estimate all the state variables from noisy measurements of fuselage pitch/roll angles and from noisy measurements of both fuselage and rotor pitch/roll angles. The mean square response of the vehicle to a very gusty, random wind is computed using various filter/controllers and is found to be quite satisfactory although, of course, not so good as when one has perfect information (idealized case). The second part of the report considers precision hover over a point on the ground. A vehicle model without rotor dynamics is used and feedback signals in position and integral of position error are added. The mean square response of the vehicle to a very gusty, random wind is computed, assuming perfect information feedback, and is found to be excellent. The integral error feedback gives zero position error for a steady wind, and smaller position error for a random wind.

  6. Elastic collisions of classical point particles on a finite frictionless linear track with perfectly reflecting endpoints

    NASA Astrophysics Data System (ADS)

    DeLuca, R.

    2006-03-01

    Repeated elastic collisions of point particles on a finite frictionless linear track with perfectly reflecting endpoints are considered. The problem is analysed by means of an elementary linear algebra approach. It is found that, starting with a state consisting of a projectile particle in motion at constant velocity and a target particle at rest in a fixed known position, the points at which collisions occur on track, when plotted versus progressive numerals, corresponding to the collisions themselves, show periodic patterns for a rather large choice of values of the initial position x(0) and on the mass ratio r. For certain values of these parameters, however, only regular behaviour over a large number of collisions is detected.

  7. Fracture size and transmissivity correlations: Implications for transport simulations in sparse three-dimensional discrete fracture networks following a truncated power law distribution of fracture size

    NASA Astrophysics Data System (ADS)

    Hyman, J. D.; Aldrich, G.; Viswanathan, H.; Makedonska, N.; Karra, S.

    2016-08-01

    We characterize how different fracture size-transmissivity relationships influence flow and transport simulations through sparse three-dimensional discrete fracture networks. Although it is generally accepted that there is a positive correlation between a fracture's size and its transmissivity/aperture, the functional form of that relationship remains a matter of debate. Relationships that assume perfect correlation, semicorrelation, and noncorrelation between the two have been proposed. To study the impact that adopting one of these relationships has on transport properties, we generate multiple sparse fracture networks composed of circular fractures whose radii follow a truncated power law distribution. The distribution of transmissivities are selected so that the mean transmissivity of the fracture networks are the same and the distributions of aperture and transmissivity in models that include a stochastic term are also the same. We observe that adopting a correlation between a fracture size and its transmissivity leads to earlier breakthrough times and higher effective permeability when compared to networks where no correlation is used. While fracture network geometry plays the principal role in determining where transport occurs within the network, the relationship between size and transmissivity controls the flow speed. These observations indicate DFN modelers should be aware that breakthrough times and effective permeabilities can be strongly influenced by such a relationship in addition to fracture and network statistics.

  8. X-ray Microscopic Characterization of Protein Crystals

    NASA Technical Reports Server (NTRS)

    Hu, Z. W.; Holmes, A.; Thomas, B.R.; Chernov, a. A.; Chu, Y. S.; Lai, B.

    2004-01-01

    The microscopic mapping of the variation in degree of perfection and in type of defects in entire protein crystals by x-rays may well be a prerequisite for better understanding causes of lattice imperfections, the growth history, and properties of protein crystals. However, x-ray microscopic characterization of bulk protein crystals, in the as-grown state, is frequently more challenging than that of small molecular crystals due to the experimental difficulties arising largely from the unique features possessed by protein crystals. In this presentation, we will illustrate ssme recent activities in employing coherence-based phase contrast x-ray imaging and high-angular-resolution diffraction techniques for mapping microdefects and the degree of perfection of protein crystals, and demonstrate a correlation between crystal perfection, diffraction phenomena., and crystallization conditions. The observed features and phenomena will be discussed in context to gain insight into the nature of defects, nucleation and growth, and the properties of protein crystals.

  9. The influence of materialism and ideal body internalization on body-dissatisfaction and body-shaping behaviors of young men and women: support for the Consumer Culture Impact Model.

    PubMed

    Guðnadóttir, Unnur; Garðarsdóttir, Ragna B

    2014-04-01

    Exposure to media images of the 'body-perfect' ideal has been partly blamed for the pursuit of thinness among women and muscularity among men. Research has largely overlooked the materialistic messages frequently associated with these images. We present findings from two studies with Icelandic students aged 18-21, one focusing on young women (n = 303) and one on young men (n = 226), which test associations of materialistic and body-perfect ideals with body dissatisfaction and excessive body shaping behaviors. In both studies, the internalization of materialistic values is strongly linked to the internalization of body-perfect ideals: the thin-ideal for young women, and the muscular-ideal for young men. A materialist value orientation also predicted body dissatisfaction in both studies, and was linked to body shaping behaviors, albeit differently for young women and men. Thus, the research identifies materialism as a further correlate of both body dissatisfaction and excessive body-shaping behaviors. The findings support Dittmar's (2008) Consumer Culture Impact Model, which proposes that the body-perfect and 'material good life' ideals jointly impact well-being. © 2014 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  10. The control of the controller: molecular mechanisms for robust perfect adaptation and temperature compensation.

    PubMed

    Ni, Xiao Yu; Drengstig, Tormod; Ruoff, Peter

    2009-09-02

    Organisms have the property to adapt to a changing environment and keep certain components within a cell regulated at the same level (homeostasis). "Perfect adaptation" describes an organism's response to an external stepwise perturbation by regulating some of its variables/components precisely to their original preperturbation values. Numerous examples of perfect adaptation/homeostasis have been found, as for example, in bacterial chemotaxis, photoreceptor responses, MAP kinase activities, or in metal-ion homeostasis. Two concepts have evolved to explain how perfect adaptation may be understood: In one approach (robust perfect adaptation), the adaptation is a network property, which is mostly, but not entirely, independent of rate constant values; in the other approach (nonrobust perfect adaptation), a fine-tuning of rate constant values is needed. Here we identify two classes of robust molecular homeostatic mechanisms, which compensate for environmental variations in a controlled variable's inflow or outflow fluxes, and allow for the presence of robust temperature compensation. These two classes of homeostatic mechanisms arise due to the fact that concentrations must have positive values. We show that the concept of integral control (or integral feedback), which leads to robust homeostasis, is associated with a control species that has to work under zero-order flux conditions and does not necessarily require the presence of a physico-chemical feedback structure. There are interesting links between the two identified classes of homeostatic mechanisms and molecular mechanisms found in mammalian iron and calcium homeostasis, indicating that homeostatic mechanisms may underlie similar molecular control structures.

  11. Statistical analysis of dynamic fibrils observed from NST/BBSO observations

    NASA Astrophysics Data System (ADS)

    Gopalan Priya, Thambaje; Su, Jiang-Tao; Chen, Jie; Deng, Yuan-Yong; Prasad Choudhury, Debi

    2018-02-01

    We present the results obtained from the analysis of dynamic fibrils in NOAA active region (AR) 12132, using high resolution Hα observations from the New Solar Telescope operating at Big Bear Solar Observatory. The dynamic fibrils are seen to be moving up and down, and most of these dynamic fibrils are periodic and have a jet-like appearance. We found from our observations that the fibrils follow almost perfect parabolic paths in many cases. A statistical analysis on the properties of the parabolic paths showing an analysis on deceleration, maximum velocity, duration and kinetic energy of these fibrils is presented here. We found the average maximum velocity to be around 15 kms‑1 and mean deceleration to be around 100 ms‑2. The observed deceleration appears to be a fraction of gravity of the Sun and is not compatible with the path of ballistic motion due to gravity of the Sun. We found a positive correlation between deceleration and maximum velocity. This correlation is consistent with simulations done earlier on magnetoacoustic shock waves propagating upward.

  12. On subgame perfect equilibria in quantum Stackelberg duopoly

    NASA Astrophysics Data System (ADS)

    Frąckiewicz, Piotr; Pykacz, Jarosław

    2018-02-01

    Our purpose is to study the Stackelberg duopoly with the use of the Li-Du-Massar quantum duopoly scheme. The result of Lo and Kiang has shown that the correlation of players's quantities caused by the quantum entanglement enlarges the first-mover advantage in the quantum Stackelberg duopoly. However, the interval of entanglement parameters for which this result is valid is bounded from above. It has been an open question what the equilibrium result is over the upper bound, in particular when the entanglement parameter goes to infinity. Our work provides complete analysis of subgame perfect equilibria of the game for all the values of the entanglement parameter.

  13. Developing the Perfect Pitch: Creating a Positive First Impression through Social Media

    ERIC Educational Resources Information Center

    Edmiston, Dawn

    2016-01-01

    Too often we take for granted first impressions and how others perceive us, but such perceptions frequently form the basis for personal and professional success. Today, many first impressions are made online through search engine results and social networks. To ensure that students make a positive first impression, this teaching innovation…

  14. Re-Thinking Ballet Pedagogy: Approaching a Historiography of Fifth Position

    ERIC Educational Resources Information Center

    Morris, Merry Lynn

    2015-01-01

    This article addresses the use of the fifth position in historical and current dance training practices with particular emphasis upon examining the 180° aesthetic and its hegemonic, idealized persistence in dancing bodies, as a marker of perfection and "beauty". Historical research is interwoven with practice-based experience and dance…

  15. Fans, Football and Federal Elections: A Real-World Example of Statistics

    ERIC Educational Resources Information Center

    Cramer, Kenneth M.; Jackson, Dennis L.

    2006-01-01

    This article evaluates and explores the correlation (+0.892) between the United States federal election winner and the most recent Washington Redskin home-game winner, a relation perfectly linked for 17 of 18 elections since franchise inception in 1936.

  16. Perfect count: a novel approach for the single platform enumeration of absolute CD4+ T-lymphocytes.

    PubMed

    Storie, Ian; Sawle, Alex; Goodfellow, Karen; Whitby, Liam; Granger, Vivian; Ward, Rosalie Y; Peel, Janet; Smart, Theresa; Reilly, John T; Barnett, David

    2004-01-01

    The derivation of reliable CD4(+) T lymphocyte counts is vital for the monitoring of disease progression and therapeutic effectiveness in HIV(+) individuals. Flow cytometry has emerged as the method of choice for CD4(+) T lymphocyte enumeration, with single-platform technology, coupled with reference counting beads, fast becoming the "gold standard." However, although single-platform, bead-based, sample acquisition requires the ratio of beads to cells to remain unchanged, there is no available method, until recently, to monitor this. Perfect Count beads have been developed to address this issue and to incorporate two bead populations, with different densities, to allow the detection of inadequate mixing. Comparison of the relative proportions of both beads with the manufacture's defined limits enables an internal QC check during sample acquisition. In this study, we have compared CD4(+) T lymphocyte counts, obtained from 104 HIV(+) patients, using TruCount beads with MultiSet software (defined as the predicated method) and the new Perfect Count beads, incorporating an in house sequential gating strategy. We have demonstrated an excellent degree of correlation between the predicate method and the Perfect Count system (r(2) = 0.9955; Bland Altman bias +27 CD4(+) T lymphocytes/microl). The Perfect Count system is a robust method for performing single platform absolute counts and has the added advantage of having internal QC checks. Such an approach enables the operator to identify potential problems during sample preparation, acquisition and analysis. Copyright 2003 Wiley-Liss, Inc.

  17. Fracture size and transmissivity correlations: Implications for transport simulations in sparse three-dimensional discrete fracture networks following a truncated power law distribution of fracture size

    DOE PAGES

    Hyman, Jeffrey De'Haven; Aldrich, Garrett Allen; Viswanathan, Hari S.; ...

    2016-08-01

    We characterize how different fracture size-transmissivity relationships influence flow and transport simulations through sparse three-dimensional discrete fracture networks. Although it is generally accepted that there is a positive correlation between a fracture's size and its transmissivity/aperture, the functional form of that relationship remains a matter of debate. Relationships that assume perfect correlation, semicorrelation, and noncorrelation between the two have been proposed. To study the impact that adopting one of these relationships has on transport properties, we generate multiple sparse fracture networks composed of circular fractures whose radii follow a truncated power law distribution. The distribution of transmissivities are selected somore » that the mean transmissivity of the fracture networks are the same and the distributions of aperture and transmissivity in models that include a stochastic term are also the same. We observe that adopting a correlation between a fracture size and its transmissivity leads to earlier breakthrough times and higher effective permeability when compared to networks where no correlation is used. While fracture network geometry plays the principal role in determining where transport occurs within the network, the relationship between size and transmissivity controls the flow speed. Lastly, these observations indicate DFN modelers should be aware that breakthrough times and effective permeabilities can be strongly influenced by such a relationship in addition to fracture and network statistics.« less

  18. Fracture size and transmissivity correlations: Implications for transport simulations in sparse three-dimensional discrete fracture networks following a truncated power law distribution of fracture size

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hyman, Jeffrey De'Haven; Aldrich, Garrett Allen; Viswanathan, Hari S.

    We characterize how different fracture size-transmissivity relationships influence flow and transport simulations through sparse three-dimensional discrete fracture networks. Although it is generally accepted that there is a positive correlation between a fracture's size and its transmissivity/aperture, the functional form of that relationship remains a matter of debate. Relationships that assume perfect correlation, semicorrelation, and noncorrelation between the two have been proposed. To study the impact that adopting one of these relationships has on transport properties, we generate multiple sparse fracture networks composed of circular fractures whose radii follow a truncated power law distribution. The distribution of transmissivities are selected somore » that the mean transmissivity of the fracture networks are the same and the distributions of aperture and transmissivity in models that include a stochastic term are also the same. We observe that adopting a correlation between a fracture size and its transmissivity leads to earlier breakthrough times and higher effective permeability when compared to networks where no correlation is used. While fracture network geometry plays the principal role in determining where transport occurs within the network, the relationship between size and transmissivity controls the flow speed. Lastly, these observations indicate DFN modelers should be aware that breakthrough times and effective permeabilities can be strongly influenced by such a relationship in addition to fracture and network statistics.« less

  19. Associative Asymmetry of Compound Words

    ERIC Educational Resources Information Center

    Caplan, Jeremy B.; Boulton, Kathy L.; Gagné, Christina L.

    2014-01-01

    Early verbal-memory researchers assumed participants represent memory of a pair of unrelated items with 2 independent, separately modifiable, directional associations. However, memory for pairs of unrelated words (A-B) exhibits associative symmetry: a near-perfect correlation between accuracy on forward (A??) and backward (??B) cued recall. This…

  20. Electron Correlation from the Adiabatic Connection for Multireference Wave Functions

    NASA Astrophysics Data System (ADS)

    Pernal, Katarzyna

    2018-01-01

    An adiabatic connection (AC) formula for the electron correlation energy is derived for a broad class of multireference wave functions. The AC expression recovers dynamic correlation energy and assures a balanced treatment of the correlation energy. Coupling the AC formalism with the extended random phase approximation allows one to find the correlation energy only from reference one- and two-electron reduced density matrices. If the generalized valence bond perfect pairing model is employed a simple closed-form expression for the approximate AC formula is obtained. This results in the overall M5 scaling of the computation cost making the method one of the most efficient multireference approaches accounting for dynamic electron correlation also for the strongly correlated systems.

  1. So Perfect It's Positively Harmful?: Reflections on the Adaptiveness and Maladaptiveness of Positive and Negative Perfectionism

    ERIC Educational Resources Information Center

    Owens, R. Glynn; Slade, Peter D.

    2008-01-01

    The article by Flatt and Hewitt (2006) highlights a number of important issues in the study of perfectionism and rightly urges caution against simplistic conceptualizations. Their view that the term "perfectionism" should be reserved for pathological forms of behavior is questionable, though understandable given the perspective from which they…

  2. Parenting with Positive Behavior Support: A Practical Guide to Resolving Your Child's Difficult Behavior

    ERIC Educational Resources Information Center

    Hieneman, Meme; Childs, Karen; Sergay, Jane

    2006-01-01

    Now the theory and research behind the positive behavior support (PBS) process--an approach already proven effective in schools and community programs--has been transformed into a practical, easy-to-use guide that's perfect for sharing with parents. Developed by educators and families, this user-friendly handbook offers parents easy-to-follow…

  3. Effect of imperfections on the hyperuniformity of many-body systems

    NASA Astrophysics Data System (ADS)

    Kim, Jaeuk; Torquato, Salvatore

    2018-02-01

    A hyperuniform many-body system is characterized by a structure factor S (k ) that vanishes in the small-wave-number limit or equivalently by a local number variance σN2(R ) associated with a spherical window of radius R that grows more slowly than Rd in the large-R limit. Thus, the hyperuniformity implies anomalous suppression of long-wavelength density fluctuations relative to those in typical disordered systems, i.e., σN2(R ) ˜Rd as R →∞ . Hyperuniform systems include perfect crystals, quasicrystals, and special disordered systems. Disordered hyperuniform systems are amorphous states of matter that lie between a liquid and crystal [S. Torquato et al., Phys. Rev. X 5, 021020 (2015), 10.1103/PhysRevX.5.021020], and have been the subject of many recent investigations due to their novel properties. In the same way that there is no perfect crystal in practice due to the inevitable presence of imperfections, such as vacancies and dislocations, there is no "perfect" hyperuniform system, whether it is ordered or not. Thus, it is practically and theoretically important to quantitatively understand the extent to which imperfections introduced in a perfectly hyperuniform system can degrade or destroy its hyperuniformity and corresponding physical properties. This paper begins such a program by deriving explicit formulas for S (k ) in the small-wave-number regime for three types of imperfections: (1) uncorrelated point defects, including vacancies and interstitials, (2) stochastic particle displacements, and (3) thermal excitations in the classical harmonic regime. We demonstrate that our results are in excellent agreement with numerical simulations. We find that "uncorrelated" vacancies or interstitials destroy hyperuniformity in proportion to the defect concentration p . We show that "uncorrelated" stochastic displacements in perfect lattices can never destroy the hyperuniformity but it can be degraded such that the perturbed lattices fall into class III hyperuniform systems, where σN2(R ) ˜Rd -α as R →∞ and 0 <α <1 . By contrast, we demonstrate that certain "correlated" displacements can make systems nonhyperuniform. For a perfect (ground-state) crystal at zero temperature, increase in temperature T introduces such correlated displacements resulting from thermal excitations, and thus the thermalized crystal becomes nonhyperuniform, even at an arbitrarily low temperature. It is noteworthy that imperfections in disordered hyperuniform systems can be unambiguously detected. Our work provides the theoretical underpinnings to systematically study the effect of imperfections on the physical properties of hyperuniform materials.

  4. 210Po Log-normal distribution in human urines: Survey from Central Italy people

    PubMed Central

    Sisti, D.; Rocchi, M. B. L.; Meli, M. A.; Desideri, D.

    2009-01-01

    The death in London of the former secret service agent Alexander Livtinenko on 23 November 2006 generally attracted the attention of the public to the rather unknown radionuclide 210Po. This paper presents the results of a monitoring programme of 210Po background levels in the urines of noncontaminated people living in Central Italy (near the Republic of S. Marino). The relationship between age, sex, years of smoking, number of cigarettes per day, and 210Po concentration was also studied. The results indicated that the urinary 210Po concentration follows a surprisingly perfect Log-normal distribution. Log 210Po concentrations were positively correlated to age (p < 0.0001), number of daily smoked cigarettes (p = 0.006), and years of smoking (p = 0.021), and associated to sex (p = 0.019). Consequently, this study provides upper reference limits for each sub-group identified by significantly predictive variables. PMID:19750019

  5. Pressure distribution under flexible polishing tools. I - Conventional aspheric optics

    NASA Astrophysics Data System (ADS)

    Mehta, Pravin K.; Hufnagel, Robert E.

    1990-10-01

    The paper presents a mathematical model, based on Kirchoff's thin flat plate theory, developed to determine polishing pressure distribution for a flexible polishing tool. A two-layered tool in which bending and compressive stiffnesses are equal is developed, which is formulated as a plate on a linearly elastic foundation. An equivalent eigenvalue problem and solution for a free-free plate are created from the plate formulation. For aspheric, anamorphic optical surfaces, the tool misfit is derived; it is defined as the result of movement from the initial perfect fit on the optic to any other position. The Polisher Design (POD) software for circular tools on aspheric optics is introduced. NASTRAN-based finite element analysis results are compared with the POD software, showing high correlation. By employing existing free-free eigenvalues and eigenfunctions, the work may be extended to rectangular polishing tools as well.

  6. High-speed cylindrical collapse of two perfect fluids

    NASA Astrophysics Data System (ADS)

    Sharif, M.; Ahmad, Zahid

    2007-09-01

    In this paper, the study of the gravitational collapse of cylindrically distributed two perfect fluid system has been carried out. It is assumed that the collapsing speeds of the two fluids are very large. We explore this condition by using the high-speed approximation scheme. There arise two cases, i.e., bounded and vanishing of the ratios of the pressures with densities of two fluids given by c s , d s . It is shown that the high-speed approximation scheme breaks down by non-zero pressures p 1, p 2 when c s , d s are bounded below by some positive constants. The failure of the high-speed approximation scheme at some particular time of the gravitational collapse suggests the uncertainty on the evolution at and after this time. In the bounded case, the naked singularity formation seems to be impossible for the cylindrical two perfect fluids. For the vanishing case, if a linear equation of state is used, the high-speed collapse does not break down by the effects of the pressures and consequently a naked singularity forms. This work provides the generalisation of the results already given by Nakao and Morisawa (Prog Theor Phys 113:73, 2005) for the perfect fluid.

  7. An investigation of immune system disorder as a "marker" for anomalous dominance.

    PubMed

    Rich, D A; McKeever, W F

    1990-01-01

    Geschwind and Galaburda (1987) proposed that immune disorder (ID) susceptibility, along with left handedness and familial sinistrality (FS), is a "marker" for anomalous dominance. The theory predicts lesser left lateralization for language processes, lessened left hemisphere abilities, and enhanced right hemisphere abilities. We assessed language laterality (dichotic consonant vowel task) and performances on spatial and verbal tasks. Subjects were 128 college students. The factors of handedness, sex, FS, and immune disorder history (negative or positive) were perfectly counterbalanced. Left-handers were significantly less lateralized for language and scored lower than right-handers on the spatial tasks. Females scored lower on mental rotation than males, but performed comparably to males on the spatial relations task. The only effect of ID was by way of interaction with FS on both spatial tasks--subjects who were either negative or positive on both FS and ID status factors scored significantly higher than subjects negative for one but positive for the other factor. A speculative explanatory model for this interaction was proposed. The model incorporates the notion that FS and ID factors are comparably correlated, but in opposite directions, with hormonal factors implicated by other research as relevant for spatial ability differences. Finally, no support for the "anomalous dominance" hypothesis predictions was found.

  8. A Novel Three-Dimensional Vector Analysis of Axial Globe Position in Thyroid Eye Disease

    PubMed Central

    Guo, Jie; Yuan, Yifei; Zhang, Rui; Huang, Wenhu

    2017-01-01

    Purpose. To define a three-dimensional (3D) vector method to describe the axial globe position in thyroid eye disease (TED). Methods. CT data from 59 patients with TED were collected and 3D images were reconstructed. A reference coordinate system was established, and the coordinates of the corneal apex and the eyeball center were calculated to obtain the globe vector EC→. The measurement reliability was evaluated. The parameters of EC→ were analyzed and compared with the results of two-dimensional (2D) CT measurement, Hertel exophthalmometry, and strabismus tests. Results. The reliability of EC→ measurement was excellent. The difference between EC→ and 2D CT measurement was significant (p = 0.003), and EC→ was more consistent with Hertel exophthalmometry than with 2D CT measurement (p < 0.001). There was no significant difference between EC→ and Hirschberg test, and a strong correlation was found between EC→ and synoptophore test. When one eye had a larger deviation angle than its fellow, its corneal apex shifted in the corresponding direction, but the shift of the eyeball center was not significant. The parameters of EC→ were almost perfectly consistent with the geometrical equation. Conclusions. The establishment of a 3D globe vector is feasible and reliable, and it could provide more information in the axial globe position. PMID:28491471

  9. Prediction of brain-computer interface aptitude from individual brain structure.

    PubMed

    Halder, S; Varkuti, B; Bogdan, M; Kübler, A; Rosenstiel, W; Sitaram, R; Birbaumer, N

    2013-01-01

    Brain-computer interface (BCI) provide a non-muscular communication channel for patients with impairments of the motor system. A significant number of BCI users is unable to obtain voluntary control of a BCI-system in proper time. This makes methods that can be used to determine the aptitude of a user necessary. We hypothesized that integrity and connectivity of involved white matter connections may serve as a predictor of individual BCI-performance. Therefore, we analyzed structural data from anatomical scans and DTI of motor imagery BCI-users differentiated into high and low BCI-aptitude groups based on their overall performance. Using a machine learning classification method we identified discriminating structural brain trait features and correlated the best features with a continuous measure of individual BCI-performance. Prediction of the aptitude group of each participant was possible with near perfect accuracy (one error). Tissue volumetric analysis yielded only poor classification results. In contrast, the structural integrity and myelination quality of deep white matter structures such as the Corpus Callosum, Cingulum, and Superior Fronto-Occipital Fascicle were positively correlated with individual BCI-performance. This confirms that structural brain traits contribute to individual performance in BCI use.

  10. Prediction of brain-computer interface aptitude from individual brain structure

    PubMed Central

    Halder, S.; Varkuti, B.; Bogdan, M.; Kübler, A.; Rosenstiel, W.; Sitaram, R.; Birbaumer, N.

    2013-01-01

    Objective: Brain-computer interface (BCI) provide a non-muscular communication channel for patients with impairments of the motor system. A significant number of BCI users is unable to obtain voluntary control of a BCI-system in proper time. This makes methods that can be used to determine the aptitude of a user necessary. Methods: We hypothesized that integrity and connectivity of involved white matter connections may serve as a predictor of individual BCI-performance. Therefore, we analyzed structural data from anatomical scans and DTI of motor imagery BCI-users differentiated into high and low BCI-aptitude groups based on their overall performance. Results: Using a machine learning classification method we identified discriminating structural brain trait features and correlated the best features with a continuous measure of individual BCI-performance. Prediction of the aptitude group of each participant was possible with near perfect accuracy (one error). Conclusions: Tissue volumetric analysis yielded only poor classification results. In contrast, the structural integrity and myelination quality of deep white matter structures such as the Corpus Callosum, Cingulum, and Superior Fronto-Occipital Fascicle were positively correlated with individual BCI-performance. Significance: This confirms that structural brain traits contribute to individual performance in BCI use. PMID:23565083

  11. Validation of PC-based Sound Card with Biopac for Digitalization of ECG Recording in Short-term HRV Analysis.

    PubMed

    Maheshkumar, K; Dilara, K; Maruthy, K N; Sundareswaren, L

    2016-07-01

    Heart rate variability (HRV) analysis is a simple and noninvasive technique capable of assessing autonomic nervous system modulation on heart rate (HR) in healthy as well as disease conditions. The aim of the present study was to compare (validate) the HRV using a temporal series of electrocardiograms (ECG) obtained by simple analog amplifier with PC-based sound card (audacity) and Biopac MP36 module. Based on the inclusion criteria, 120 healthy participants, including 72 males and 48 females, participated in the present study. Following standard protocol, 5-min ECG was recorded after 10 min of supine rest by Portable simple analog amplifier PC-based sound card as well as by Biopac module with surface electrodes in Leads II position simultaneously. All the ECG data was visually screened and was found to be free of ectopic beats and noise. RR intervals from both ECG recordings were analyzed separately in Kubios software. Short-term HRV indexes in both time and frequency domain were used. The unpaired Student's t-test and Pearson correlation coefficient test were used for the analysis using the R statistical software. No statistically significant differences were observed when comparing the values analyzed by means of the two devices for HRV. Correlation analysis revealed perfect positive correlation (r = 0.99, P < 0.001) between the values in time and frequency domain obtained by the devices. On the basis of the results of the present study, we suggest that the calculation of HRV values in the time and frequency domains by RR series obtained from the PC-based sound card is probably as reliable as those obtained by the gold standard Biopac MP36.

  12. The digital computer as a metaphor for the perfect laboratory experiment: Loophole-free Bell experiments

    NASA Astrophysics Data System (ADS)

    De Raedt, Hans; Michielsen, Kristel; Hess, Karl

    2016-12-01

    Using Einstein-Podolsky-Rosen-Bohm experiments as an example, we demonstrate that the combination of a digital computer and algorithms, as a metaphor for a perfect laboratory experiment, provides solutions to problems of the foundations of physics. Employing discrete-event simulation, we present a counterexample to John Bell's remarkable "proof" that any theory of physics, which is both Einstein-local and "realistic" (counterfactually definite), results in a strong upper bound to the correlations that are being measured in Einstein-Podolsky-Rosen-Bohm experiments. Our counterexample, which is free of the so-called detection-, coincidence-, memory-, and contextuality loophole, violates this upper bound and fully agrees with the predictions of quantum theory for Einstein-Podolsky-Rosen-Bohm experiments.

  13. Effective conductivity of a periodic dilute composite with perfect contact and its series expansion

    NASA Astrophysics Data System (ADS)

    Pukhtaievych, Roman

    2018-06-01

    We study the asymptotic behavior of the effective thermal conductivity of a periodic two-phase dilute composite obtained by introducing into an infinite homogeneous matrix a periodic set of inclusions of a different material, each of them of size proportional to a positive parameter ɛ . We assume a perfect thermal contact at constituent interfaces, i.e., a continuity of the normal component of the heat flux and of the temperature. For ɛ small, we prove that the effective conductivity can be represented as a convergent power series in ɛ and we determine the coefficients in terms of the solutions of explicit systems of integral equations.

  14. Long-range correlation properties of coding and noncoding DNA sequences: GenBank analysis.

    PubMed

    Buldyrev, S V; Goldberger, A L; Havlin, S; Mantegna, R N; Matsa, M E; Peng, C K; Simons, M; Stanley, H E

    1995-05-01

    An open question in computational molecular biology is whether long-range correlations are present in both coding and noncoding DNA or only in the latter. To answer this question, we consider all 33301 coding and all 29453 noncoding eukaryotic sequences--each of length larger than 512 base pairs (bp)--in the present release of the GenBank to dtermine whether there is any statistically significant distinction in their long-range correlation properties. Standard fast Fourier transform (FFT) analysis indicates that coding sequences have practically no correlations in the range from 10 bp to 100 bp (spectral exponent beta=0.00 +/- 0.04, where the uncertainty is two standard deviations). In contrast, for noncoding sequences, the average value of the spectral exponent beta is positive (0.16 +/- 0.05) which unambiguously shows the presence of long-range correlations. We also separately analyze the 874 coding and the 1157 noncoding sequences that have more than 4096 bp and find a larger region of power-law behavior. We calculate the probability that these two data sets (coding and noncoding) were drawn from the same distribution and we find that it is less than 10(-10). We obtain independent confirmation of these findings using the method of detrended fluctuation analysis (DFA), which is designed to treat sequences with statistical heterogeneity, such as DNA's known mosaic structure ("patchiness") arising from the nonstationarity of nucleotide concentration. The near-perfect agreement between the two independent analysis methods, FFT and DFA, increases the confidence in the reliability of our conclusion.

  15. Long-range correlation properties of coding and noncoding DNA sequences: GenBank analysis

    NASA Technical Reports Server (NTRS)

    Buldyrev, S. V.; Goldberger, A. L.; Havlin, S.; Mantegna, R. N.; Matsa, M. E.; Peng, C. K.; Simons, M.; Stanley, H. E.

    1995-01-01

    An open question in computational molecular biology is whether long-range correlations are present in both coding and noncoding DNA or only in the latter. To answer this question, we consider all 33301 coding and all 29453 noncoding eukaryotic sequences--each of length larger than 512 base pairs (bp)--in the present release of the GenBank to dtermine whether there is any statistically significant distinction in their long-range correlation properties. Standard fast Fourier transform (FFT) analysis indicates that coding sequences have practically no correlations in the range from 10 bp to 100 bp (spectral exponent beta=0.00 +/- 0.04, where the uncertainty is two standard deviations). In contrast, for noncoding sequences, the average value of the spectral exponent beta is positive (0.16 +/- 0.05) which unambiguously shows the presence of long-range correlations. We also separately analyze the 874 coding and the 1157 noncoding sequences that have more than 4096 bp and find a larger region of power-law behavior. We calculate the probability that these two data sets (coding and noncoding) were drawn from the same distribution and we find that it is less than 10(-10). We obtain independent confirmation of these findings using the method of detrended fluctuation analysis (DFA), which is designed to treat sequences with statistical heterogeneity, such as DNA's known mosaic structure ("patchiness") arising from the nonstationarity of nucleotide concentration. The near-perfect agreement between the two independent analysis methods, FFT and DFA, increases the confidence in the reliability of our conclusion.

  16. Medical and psychosocial associates of nonadherence in adolescents with cancer.

    PubMed

    Hullmann, Stephanie E; Brumley, Lauren D; Schwartz, Lisa A

    2015-01-01

    The current study examined adherence to medication regimens among adolescents with cancer by applying the Pediatric Self-Management Model. Adolescents and their parents reported on adherence to medication, reasons for nonadherence, and patient-, family-, and community-level psychosocial variables. Adolescent- and parent-reported adherence were significantly correlated, with about half of the sample reporting perfect adherence. The majority reported "just forgot" as the most common reason for missed medication. Patient-, family-, and community-level variables were examined as predictors of adherence. With regard to individual factors, adolescents who endorsed perfect adherence reported a greater proportion of future-orientated goals and spent fewer days in outpatient clinic visits. For family factors, adolescents who endorsed perfect adherence reported greater social support from their family and were more likely to have a second caregiver who they perceived as overprotective. The community-level variable (social support from friends) tested did not emerge as a predictor of adherence. The results of this study provide direction for intervention efforts to target adolescent goals and family support in order to increase adolescent adherence to cancer treatment regimens. © 2014 by Association of Pediatric Hematology/Oncology Nurses.

  17. Medical and Psychosocial Associates of Nonadherence in Adolescents With Cancer

    PubMed Central

    Hullmann, Stephanie E.; Brumley, Lauren D.; Schwartz, Lisa A.

    2015-01-01

    The current study examined adherence to medication regimens among adolescents with cancer by applying the Pediatric Self-Management Model. Adolescents and their parents reported on adherence to medication, reasons for nonadherence, and patient-, family-, and community-level psychosocial variables. Adolescent- and parent-reported adherence were significantly correlated, with about half of the sample reporting perfect adherence. The majority reported “just forgot” as the most common reason for missed medication. Patient-, family-, and community-level variables were examined as predictors of adherence. With regard to individual factors, adolescents who endorsed perfect adherence reported a greater proportion of future-orientated goals and spent fewer days in outpatient clinic visits. For family factors, adolescents who endorsed perfect adherence reported greater social support from their family and were more likely to have a second caregiver who they perceived as overprotective. The community-level variable (social support from friends) tested did not emerge as a predictor of adherence. The results of this study provide direction for intervention efforts to target adolescent goals and family support in order to increase adolescent adherence to cancer treatment regimens. PMID:25366574

  18. Size-dependent physicochemical and mechanical interactions in battery paste anodes of Si-microwires revealed by Fast-Fourier-Transform Impedance Spectroscopy

    NASA Astrophysics Data System (ADS)

    Hansen, Sandra; Quiroga-González, Enrique; Carstensen, Jürgen; Adelung, Rainer; Föll, Helmut

    2017-05-01

    Perfectly aligned silicon microwire arrays show exceptionally high cycling stability with record setting (high) areal capacities of 4.25 mAh cm-2. Those wires have a special, modified length and thickness in order to perform this good. Geometry and sizes are the most important parameters of an anode to obtain batteries with high cycling stability without irreversible losses. The wires are prepared with a unique etching fabrication method, which allows to fabricate wires of very precise sizes. In order to investigate how good randomly oriented silicon wires perform in contrast to the perfect order of the array, the wires are embedded in a paste. This study reveals the fundamental correlation between geometry, mechanics and charge transfer kinetics of silicon electrodes. Using a suitable RC equivalent circuit allows to evaluate data from cyclic voltammetry and simultaneous FFT-Impedance Spectroscopy (FFT-IS), yielding in time-resolved resistances, time constants, and their direct correlation to the phase transformations. The change of the resistances during lithiation and delithiation correlates to kinetics and charge transfer mechanisms. This study demonstrates how the mechanical and physiochemical interactions at the silicon/paste interface inside the paste electrodes lead to void formation around silicon and with it to material loss and capacity fading.

  19. Comparative evaluation of a rapid diagnostic test, an antibody ELISA, and a pLDH ELISA in detecting asymptomatic malaria parasitaemia in blood donors in Buea, Cameroon.

    PubMed

    Kwenti, Tebit Emmanuel; Njunda, Longdoh Anna; Tsamul, Beltine; Nsagha, Shey Dickson; Assob, Nguedia Jules-Clement; Tufon, Kukwah Anthony; Meriki, Dilonga Henry; Orock, Enow George

    2017-08-01

    In malaria endemic areas, infected blood donors serve as a source of infection to blood recipients, which may adversely affect their prognosis. This necessitates the proper screening of blood to be used for transfusion in these areas. The purpose of this study was to determine the prevalence of malaria parasitaemia in blood donors in Buea, Cameroon, and to evaluate the performance of a rapid diagnostic test (RDT), a malaria antibody enzyme-linked immunosorbent assay (ELISA), and a Plasmodium lactate dehydrogenase (pLDH) ELISA in the detection of asymptomatic malaria parasitaemia in the target population. In a prospective study conducted between September 2015 and June 2016, 1 240 potential blood donors were enrolled. The donors were screened for malaria parasites using Giemsa microscopy (GM) and a RDT. A sub-sample of 184 samples, comprising 88 positive and 96 negative samples, were selected for the evaluation of the pLDH ELISA and the antibody ELISA. The chi-square test and correlation analysis were performed as part of the statistical analyses. The statistical significance cut-off was set at P < 0.05. The prevalence of malaria parasitaemia in this study was found to be 8.1% (95% CI: 6.6 - 9.7). The prevalence was not observed to be dependent on the age or sex of the participants. The RDT had a sensitivity (88.0%), specificity (99.1%), and negative predictive value (99.0%) higher than the ELISAs. The performance of the pLDH ELISA, which demonstrated the highest positive predictive value (91.6%), was generally comparable to the RDT. The sensitivity was lowest with the antibody ELISA (69.9%), which also demonstrated the highest false positive and false negative rates. The detection threshold for the pLDH (three parasites/μl) was lower compared to the RDT (50 - 60 parasites/μl). Non-significant positive correlations were observed between the parasite density and the pLDH titers and malaria antibody titers. Overall, the RDT and the pLDH ELISA demonstrated a perfectly correlated agreement with GM, meanwhile the antibody ELISA demonstrated a substantially correlated agreement with GM. The pLDH is therefore recommended for mass screening of blood (to detect malaria parasitaemia) for transfusions in the study area. However, where this is not feasible, an RDT will suffice.

  20. At Home Photography-Based Method for Measuring Wrist Range of Motion.

    PubMed

    Trehan, Samir K; Rancy, Schneider K; Johnsen, Parker H; Hillstrom, Howard J; Lee, Steve K; Wolfe, Scott W

    2017-11-01

    Purpose  To determine the reliability of wrist range of motion (WROM) measurements based on digital photographs taken by patients at home compared with traditional measurements done in the office with a goniometer. Methods  Sixty-nine postoperative patients were enrolled in this study at least 3 months postoperatively. Active and passive wrist flexion/extension and radial/ulnar deviation were recorded by one of the two attending surgeons with a 1-degree resolution goniometer at the last postoperative office visit. Patients were provided an illustrated instruction sheet detailing how to take digital photographic images at home in six wrist positions (active and passive flexion/extension, and radial/ulnar deviation). Wrist position was measured from digital images by both the attending surgeons in a randomized, blinded fashion on two separate occasions greater than 2 weeks apart using the same goniometer. Reliability analysis was performed using the intraclass correlation coefficient to assess agreement between clinical and photography-based goniometry, as well as intra- and interobserver agreement. Results  Out of 69 enrolled patients, 30 (43%) patients sent digital images. Of the 180 digital photographs, only 9 (5%) were missing or deemed inadequate for WROM measurements. Agreement between clinical and photography-based measurements was "almost perfect" for passive wrist flexion/extension and "substantial" for active wrist flexion/extension and radial/ulnar deviation. Inter- and intraobserver agreement for the attending surgeons was "almost perfect" for all measurements. Discussion  This study validates a photography-based goniometry protocol allowing accurate and reliable WROM measurements without direct physician contact. Passive WROM was more accurately measured from photographs than active WROM. This study builds on previous photography-based goniometry literature by validating a protocol in which patients or their families take and submit their own photographs. Clinical Relevance  Patient-performed photography-based goniometry represents an alternative to traditional clinical goniometry that could enable longer-term follow-up, overcome travel-related impediments to office visits, improve convenience, and reduce costs for patients.

  1. Proliferation assessment in breast carcinomas using digital image analysis based on virtual Ki67/cytokeratin double staining.

    PubMed

    Røge, Rasmus; Riber-Hansen, Rikke; Nielsen, Søren; Vyberg, Mogens

    2016-07-01

    Manual estimation of Ki67 Proliferation Index (PI) in breast carcinoma classification is labor intensive and prone to intra- and interobserver variation. Standard Digital Image Analysis (DIA) has limitations due to issues with tumor cell identification. Recently, a computer algorithm, DIA based on Virtual Double Staining (VDS), segmenting Ki67-positive and -negative tumor cells using digitally fused parallel cytokeratin (CK) and Ki67-stained slides has been introduced. In this study, we compare VDS with manual stereological counting of Ki67-positive and -negative cells and examine the impact of the physical distance of the parallel slides on the alignment of slides. TMAs, containing 140 cores of consecutively obtained breast carcinomas, were stained for CK and Ki67 using optimized staining protocols. By means of stereological principles, Ki67-positive and -negative cell profiles were counted in sampled areas and used for the estimation of PIs of the whole tissue core. The VDS principle was applied to both the same sampled areas and the whole tissue core. Additionally, five neighboring slides were stained for CK in order to examine the alignment algorithm. Correlation between manual counting and VDS in both sampled areas and whole core was almost perfect (correlation coefficients above 0.97). Bland-Altman plots did not reveal any skewness in any data ranges. There was a good agreement in alignment (>85 %) in neighboring slides, whereas agreement decreased in non-neighboring slides. VDS gave similar results compared with manual counting using stereological principles. Introduction of this method in clinical and research practice may improve accuracy and reproducibility of Ki67 PI.

  2. Cesarean Delivery Changes the Natural Position of the Uterus on Transvaginal Ultrasonography.

    PubMed

    Kaelin Agten, Andrea; Honart, Anne; Monteagudo, Ana; McClelland, Spencer; Basher, Basmy; Timor-Tritsch, Ilan E

    2018-05-01

    To assess whether cesarean delivery changes the natural position of the uterus. In this retrospective Institutional Review Board-approved cohort study, we conducted a search of our university gynecologic ultrasonography (US) database. Patients with transvaginal US images before and after either vaginal or cesarean delivery between 2012 and 2015 were included. Women with prior cesarean delivery were excluded. Two readers independently measured antepartum and postpartum flexion angles between the longitudinal axis of the uterine body and the cervix. We calculated intraclass correlation coefficients to measure inter-reader agreement. Antepartum and postpartum uterine flexion angles were compared between patients with vaginal and cesarean delivery. We included 173 patients (107 vaginal and 66 cesarean delivery). The mean interval between scans ± SD was 18 ± 10 months. Inter-reader agreement for flexion angles was almost perfect (intraclass correlation coefficients: antepartum, 0.939; postpartum, 0.969; both P < .001). There was no difference in mean antepartum flexion angles for cesarean delivery (154.8° ± 45.7°) versus vaginal delivery (145.8° ± 43.7°; P = .216). Mean postpartum flexion angles were higher after cesarean delivery (180.4° ± 51.2°) versus vaginal delivery (152.8° ± 47.7°; P = .001. Differences in antepartum and postpartum flexion angles between cesarean and vaginal delivery were statistically significant (25.6° versus 7.0°; P = .027). Cesarean delivery can change the uterine flexion angle to a more retroflexed position. Therefore, all women with a history of cesarean delivery should undergo a transvaginal US examination before any gynecologic surgery or intrauterine device placement to reduce the possibility of surgical complications. © 2017 by the American Institute of Ultrasound in Medicine.

  3. One for All & All for One

    ERIC Educational Resources Information Center

    Omotani, Les M.

    2010-01-01

    The author spent his two superintendencies perfecting a collaborative leadership concept known as "the superintendency." This concept recognized that significant change and positive, continuous improvement required long-term, concentrated attention rather than a few years of frantic activity. While the "superintendency"…

  4. Estimating acreage by double sampling using LANDSAT data

    NASA Technical Reports Server (NTRS)

    Pont, F.; Horwitz, H.; Kauth, R. (Principal Investigator)

    1982-01-01

    Double sampling techniques employing LANDSAT data for estimating the acreage of corn and soybeans was investigated and evaluated. The evaluation was based on estimated costs and correlations between two existing procedures having differing cost/variance characteristics, and included consideration of their individual merits when coupled with a fictional 'perfect' procedure of zero bias and variance. Two features of the analysis are: (1) the simultaneous estimation of two or more crops; and (2) the imposition of linear cost constraints among two or more types of resource. A reasonably realistic operational scenario was postulated. The costs were estimated from current experience with the measurement procedures involved, and the correlations were estimated from a set of 39 LACIE-type sample segments located in the U.S. Corn Belt. For a fixed variance of the estimate, double sampling with the two existing LANDSAT measurement procedures can result in a 25% or 50% cost reduction. Double sampling which included the fictional perfect procedure results in a more cost effective combination when it is used with the lower cost/higher variance representative of the existing procedures.

  5. Ab initio simulations of the structure, energetics and mobility of radiation-induced point defects in bcc Nb

    NASA Astrophysics Data System (ADS)

    Cerdeira, M. A.; Palacios, S. L.; González, C.; Fernández-Pello, D.; Iglesias, R.

    2016-09-01

    The formation, binding and migration energetics of helium clusters inside a niobium crystal have been analysed via ab initio simulations. The effect of placing several He atoms within an n-vacancy previously formed or as interstitials inside the initial perfect bulk matrix has been studied. DFT-based results show that He atoms prefer to aggregate forming small clusters at n-vacancy sites rather than at interstitial positions in the perfect crystal. The minimum formation energy is found when NHe is equal to the number of vacancies, n. It follows that vacancies act as almost perfect traps for He atoms, as is well known for other metals. The migration barriers of He atoms inside vacancies increase considerably when compared to what happens for vacancies alone. A secondary consequence is that the full set of energies obtained will be highly relevant as an input for new approaches to KMC simulations of defects in Nb.

  6. Determining Complementary Properties with Quantum Clones.

    PubMed

    Thekkadath, G S; Saaltink, R Y; Giner, L; Lundeen, J S

    2017-08-04

    In a classical world, simultaneous measurements of complementary properties (e.g., position and momentum) give a system's state. In quantum mechanics, measurement-induced disturbance is largest for complementary properties and, hence, limits the precision with which such properties can be determined simultaneously. It is tempting to try to sidestep this disturbance by copying the system and measuring each complementary property on a separate copy. However, perfect copying is physically impossible in quantum mechanics. Here, we investigate using the closest quantum analog to this copying strategy, optimal cloning. The coherent portion of the generated clones' state corresponds to "twins" of the input system. Like perfect copies, both twins faithfully reproduce the properties of the input system. Unlike perfect copies, the twins are entangled. As such, a measurement on both twins is equivalent to a simultaneous measurement on the input system. For complementary observables, this joint measurement gives the system's state, just as in the classical case. We demonstrate this experimentally using polarized single photons.

  7. Determining Complementary Properties with Quantum Clones

    NASA Astrophysics Data System (ADS)

    Thekkadath, G. S.; Saaltink, R. Y.; Giner, L.; Lundeen, J. S.

    2017-08-01

    In a classical world, simultaneous measurements of complementary properties (e.g., position and momentum) give a system's state. In quantum mechanics, measurement-induced disturbance is largest for complementary properties and, hence, limits the precision with which such properties can be determined simultaneously. It is tempting to try to sidestep this disturbance by copying the system and measuring each complementary property on a separate copy. However, perfect copying is physically impossible in quantum mechanics. Here, we investigate using the closest quantum analog to this copying strategy, optimal cloning. The coherent portion of the generated clones' state corresponds to "twins" of the input system. Like perfect copies, both twins faithfully reproduce the properties of the input system. Unlike perfect copies, the twins are entangled. As such, a measurement on both twins is equivalent to a simultaneous measurement on the input system. For complementary observables, this joint measurement gives the system's state, just as in the classical case. We demonstrate this experimentally using polarized single photons.

  8. Charge and spin correlations in the monopole liquid

    NASA Astrophysics Data System (ADS)

    Slobinsky, D.; Baglietto, G.; Borzi, R. A.

    2018-05-01

    A monopole liquid is a spin system with a high density of magnetic charges but no magnetic-charge order. We study such a liquid over an Ising pyrochlore lattice, where a single topological charge or monopole sits in each tetrahedron. Restricting the study to the case with no magnetic field applied we show that, in spite of the liquidlike correlations between charges imposed by construction constraints, the spins are uncorrelated like in a perfect paramagnet. We calculate a massive residual entropy for this phase (ln(2 )/2 , a result which is exact in the thermodynamic limit), implying a free Ising-like variable per tetrahedron. After defining a simple model Hamiltonian for this system (the balanced monopole liquid) we study its thermodynamics. Surprisingly, this monopole liquid remains a perfect paramagnet at all temperatures. Thermal disorder can then be simply and quantitatively interpreted as single charge dilution, by the excitation of neutral sites and double monopoles. The addition of the usual nearest neighbors interactions favoring neutral `2in-2out' excitations as a perturbation maintains the same ground state but induces short-range (topological) order by thermal disorder. While it decreases charge-charge correlations, pair spin correlations—resembling those in spin ice—appear on increasing temperature. This helps us to see in another light the dipolarlike correlations present in spin ices at unexpectedly high temperatures. On the other side, favoring double excitations strengthens the charges short range order and its associated spin correlations. Finally, we discuss how the monopole liquid can be related to other systems and materials where different phases of monopole matter have been observed.

  9. Performance of the Xpert HIV-1 Viral Load Assay: a Systematic Review and Meta-analysis

    PubMed Central

    Nash, Madlen; Huddart, Sophie; Badar, Sayema; Baliga, Shrikala; Saravu, Kavitha

    2018-01-01

    ABSTRACT Viral load (VL) is the preferred treatment-monitoring approach for HIV-positive patients. However, more rapid, near-patient, and low-complexity assays are needed to scale up VL testing. The Xpert HIV-1 VL assay (Cepheid, Sunnyvale, CA) is a new, automated molecular test, and it can leverage the GeneXpert systems that are being used widely for tuberculosis diagnosis. We systematically reviewed the evidence on the performance of this new tool in comparison to established reference standards. A total of 12 articles (13 studies) in which HIV patient VLs were compared between Xpert HIV VL assay and a reference standard VL assay were identified. Study quality was generally high, but substantial variability was observed in the number and type of agreement measures reported. Correlation coefficients between Xpert and reference assays were high, with a pooled Pearson correlation (n = 8) of 0.94 (95% confidence interval [CI], 0.89, 0.97) and Spearman correlation (n = 3) of 0.96 (95% CI, 0.86, 0.99). Bland-Altman metrics (n = 11) all were within 0.35 log copies/ml of perfect agreement. Overall, Xpert HIV-1 VL performed well compared to current reference tests. The minimal training and infrastructure requirements for the Xpert HIV-1 VL assay make it attractive for use in resource-constrained settings, where point-of-care VL testing is most needed. PMID:29386266

  10. Performance of the Xpert HIV-1 Viral Load Assay: a Systematic Review and Meta-analysis.

    PubMed

    Nash, Madlen; Huddart, Sophie; Badar, Sayema; Baliga, Shrikala; Saravu, Kavitha; Pai, Madhukar

    2018-04-01

    Viral load (VL) is the preferred treatment-monitoring approach for HIV-positive patients. However, more rapid, near-patient, and low-complexity assays are needed to scale up VL testing. The Xpert HIV-1 VL assay (Cepheid, Sunnyvale, CA) is a new, automated molecular test, and it can leverage the GeneXpert systems that are being used widely for tuberculosis diagnosis. We systematically reviewed the evidence on the performance of this new tool in comparison to established reference standards. A total of 12 articles (13 studies) in which HIV patient VLs were compared between Xpert HIV VL assay and a reference standard VL assay were identified. Study quality was generally high, but substantial variability was observed in the number and type of agreement measures reported. Correlation coefficients between Xpert and reference assays were high, with a pooled Pearson correlation ( n = 8) of 0.94 (95% confidence interval [CI], 0.89, 0.97) and Spearman correlation ( n = 3) of 0.96 (95% CI, 0.86, 0.99). Bland-Altman metrics ( n = 11) all were within 0.35 log copies/ml of perfect agreement. Overall, Xpert HIV-1 VL performed well compared to current reference tests. The minimal training and infrastructure requirements for the Xpert HIV-1 VL assay make it attractive for use in resource-constrained settings, where point-of-care VL testing is most needed. Copyright © 2018 Nash et al.

  11. Vlasov Treatment of Coherent Synchrotron Radiation from Arbitrary Planar Orbits

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Warnock, R

    2004-09-22

    We study the influence of coherent synchrotron radiation (CSR) on particle bunches traveling on arbitrary planar orbits between parallel conducting plates. The plates represent shielding due to the vacuum chamber. The vertical distribution of charge is an arbitrary fixed function. Our goal is to follow the time evolution of the phase space distribution by solving the Vlasov-Maxwell equations in the time domain. This provides simulations with lower numerical noise than the macroparticle method, and allows one to study such issues as emittance degradation and microbunching due to CSR in bunch compressors. The fields excited by the bunch are computed inmore » the laboratory frame from a new formula that leads to much simpler computations than the usual retarded potentials or Lienard-Wiechert potentials. The nonlinear Vlasov equation, formulated in the interaction picture, is integrated in the beam frame by approximating the Perron-Frobenius operator. The distribution function is represented by B-splines, in a scheme preserving positivity and normalization of the distribution. For application to a chicane bunch compressor we take steps to deal with energy chirp, an initial near-perfect correlation of energy with position in the bunch.« less

  12. Super Bowl Surveillance: Facing Up to Biometrics

    DTIC Science & Technology

    2001-05-01

    Biometric facial recognition can provide significant benefits to society. At the same time, the rapid growth and improvement in the technology could...using facial recognition where it can produce positive benefits. Biometric facial recognition is by no means a perfect technology, and much technical

  13. Interlaboratory and between-specimen comparisons of diagnostic tests for leptospirosis in sheep and cattle.

    PubMed

    Fang, Fang; Collins-Emerson, Julie M; Heuer, Cord; Hill, Fraser I; Tisdall, David J; Wilson, Peter R; Benschop, Jackie

    2014-11-01

    A study was performed to investigate interlaboratory test agreement between a research and a commercial veterinary diagnostic laboratory on blood and urine samples, and to investigate test agreement between blood, urine, and kidney samples (research laboratory) for leptospirosis diagnosis. Samples were sourced from 399 sheep and 146 beef cattle from a local abattoir. Interlaboratory agreement for real-time quantitative polymerase chain reaction (qPCR) results on urine samples was almost perfect (kappa = 0.90), despite the use of different amplification targets (DNA gyrase subunit B gene vs. 16s ribosomal RNA gene), chemistries (SYTO9 vs. TaqMan probe), and pre-PCR processing. Interlaboratory agreement for microscopic agglutination test (MAT) positivity was almost perfect (kappa = 0.93) for Leptospira borgpetersenii serovar Hardjo subtype Hardjobovis (Hardjobovis) but moderate (kappa = 0.53) for Leptospira interrogans serovar Pomona (Pomona). Among animals that had different titers recorded, higher Hardjobovis and lower Pomona titers were reported by the commercial laboratory than by the research laboratory (P < 0.005). These interlaboratory comparisons can assist researchers and diagnosticians in interpreting the sometimes discrepant test results. Within the research laboratory, the comparison of qPCR results on urine and kidney showed almost perfect agreement (kappa = 0.84), suggesting that the qPCR on these 2 specimens can be used interchangeably. The agreement between MAT positivity and urine and kidney qPCR results was fair (kappa = 0.32 and kappa = 0.33, respectively). However, the prevalence ratio of urine and kidney qPCR positivity in Hardjobovis-seropositive versus Hardjobovis-seronegative sheep indicated that Hardjobovis seropositivity found in sheep may be able to predict shedding or renal carriage. © 2014 The Author(s).

  14. Current correlations for the transport of interacting electrons through parallel quantum dots in a photon cavity

    NASA Astrophysics Data System (ADS)

    Gudmundsson, Vidar; Abdullah, Nzar Rauf; Sitek, Anna; Goan, Hsi-Sheng; Tang, Chi-Shung; Manolescu, Andrei

    2018-06-01

    We calculate the current correlations for the steady-state electron transport through multi-level parallel quantum dots embedded in a short quantum wire, that is placed in a non-perfect photon cavity. We account for the electron-electron Coulomb interaction, and the para- and diamagnetic electron-photon interactions with a stepwise scheme of configuration interactions and truncation of the many-body Fock spaces. In the spectral density of the temporal current-current correlations we identify all the transitions, radiative and non-radiative, active in the system in order to maintain the steady state. We observe strong signs of two types of Rabi oscillations.

  15. Mechanisms of chiral discrimination by topoisomerase IV

    PubMed Central

    Neuman, K. C.; Charvin, G.; Bensimon, D.; Croquette, V.

    2009-01-01

    Topoisomerase IV (Topo IV), an essential ATP-dependent bacterial type II topoisomerase, transports one segment of DNA through a transient double-strand break in a second segment of DNA. In vivo, Topo IV unlinks catenated chromosomes before cell division and relaxes positive supercoils generated during DNA replication. In vitro, Topo IV relaxes positive supercoils at least 20-fold faster than negative supercoils. The mechanisms underlying this chiral discrimination by Topo IV and other type II topoisomerases remain speculative. We used magnetic tweezers to measure the relaxation rates of single and multiple DNA crossings by Topo IV. These measurements allowed us to determine unambiguously the relative importance of DNA crossing geometry and enzymatic processivity in chiral discrimination by Topo IV. Our results indicate that Topo IV binds and passes DNA strands juxtaposed in a nearly perpendicular orientation and that relaxation of negative supercoiled DNA is perfectly distributive. Together, these results suggest that chiral discrimination arises primarily from dramatic differences in the processivity of relaxing positive and negative supercoiled DNA: Topo IV is highly processive on positively supercoiled DNA, whereas it is perfectly distributive on negatively supercoiled DNA. These results provide fresh insight into topoisomerase mechanisms and lead to a model that reconciles contradictory aspects of previous findings while providing a framework to interpret future results. PMID:19359479

  16. The Rhic Azimuth Quadrupole:. "perfect Liquid" or Gluonic Radiation?

    NASA Astrophysics Data System (ADS)

    Trainor, Thomas A.

    Large elliptic flow at RHIC seems to indicate that ideal hydrodynamics provides a good description of Au-Au collisions, at least at the maximum RHIC energy. The medium formed has been interpreted as a nearly perfect (low-viscosity) liquid, and connections have been made to gravitation through string theory. Recently, claimed observations of large flow fluctuations comparable to participant eccentricity fluctuations seem to confirm the ideal hydro scenario. However, determination of the azimuth quadrupole with 2D angular autocorrelations, which accurately distinguish "flow" (quadrupole) from "nonflow" (minijets), contradicts conventional interpretations. Centrality trends may depend only on the initial parton geometry, and methods used to isolate flow fluctuations are sensitive instead mainly to minijet correlations. The results presented in this paper suggest that the azimuth quadrupole may be a manifestation of gluonic multipole radiation.

  17. Constraining neutron guide optimizations with phase-space considerations

    NASA Astrophysics Data System (ADS)

    Bertelsen, Mads; Lefmann, Kim

    2016-09-01

    We introduce a method named the Minimalist Principle that serves to reduce the parameter space for neutron guide optimization when the required beam divergence is limited. The reduced parameter space will restrict the optimization to guides with a minimal neutron intake that are still theoretically able to deliver the maximal possible performance. The geometrical constraints are derived using phase-space propagation from moderator to guide and from guide to sample, while assuming that the optimized guides will achieve perfect transport of the limited neutron intake. Guide systems optimized using these constraints are shown to provide performance close to guides optimized without any constraints, however the divergence received at the sample is limited to the desired interval, even when the neutron transport is not limited by the supermirrors used in the guide. As the constraints strongly limit the parameter space for the optimizer, two control parameters are introduced that can be used to adjust the selected subspace, effectively balancing between maximizing neutron transport and avoiding background from unnecessary neutrons. One parameter is needed to describe the expected focusing abilities of the guide to be optimized, going from perfectly focusing to no correlation between position and velocity. The second parameter controls neutron intake into the guide, so that one can select exactly how aggressively the background should be limited. We show examples of guides optimized using these constraints which demonstrates the higher signal to noise than conventional optimizations. Furthermore the parameter controlling neutron intake is explored which shows that the simulated optimal neutron intake is close to the analytically predicted, when assuming that the guide is dominated by multiple scattering events.

  18. The Issue of Power in the Identification of "g" with Lower-Order Factors

    ERIC Educational Resources Information Center

    Matzke, Dora; Dolan, Conor V.; Molenaar, Dylan

    2010-01-01

    In higher order factor models, general intelligence (g) is often found to correlate perfectly with lower-order common factors, suggesting that g and some well-defined cognitive ability, such as working memory, may be identical. However, the results of studies that addressed the equivalence of g and lower-order factors are inconsistent. We suggest…

  19. A structural-phenomenological typology of mind-matter correlations.

    PubMed

    Atmanspacher, Harald; Fach, Wolfgang

    2013-04-01

    We present a typology of mind-matter correlations embedded in a dual-aspect monist framework as proposed by Pauli and Jung. They conjectured a picture in which the mental and the material arise as two complementary aspects of one underlying psychophysically neutral reality to which they cannot be reduced and to which direct empirical access is impossible. This picture suggests structural, persistent, reproducible mind-matter correlations by splitting the underlying reality into aspects. In addition, it suggests induced, occasional, evasive mind-matter correlations above and below, respectively, those stable baseline correlations. Two significant roles for the concept of meaning in this framework are elucidated. Finally, it is shown that the obtained typology is in perfect agreement with an empirically based classification of the phenomenology of mind-matter correlations as observed in exceptional human experiences. © 2013, The Society of Analytical Psychology.

  20. Cost-effective description of strong correlation: Efficient implementations of the perfect quadruples and perfect hextuples models

    DOE PAGES

    Lehtola, Susi; Parkhill, John; Head-Gordon, Martin

    2016-10-07

    Novel implementations based on dense tensor storage are presented here for the singlet-reference perfect quadruples (PQ) [J. A. Parkhill et al., J. Chem. Phys. 130, 084101 (2009)] and perfect hextuples (PH) [J. A. Parkhill and M. Head-Gordon, J. Chem. Phys. 133, 024103 (2010)] models. The methods are obtained as block decompositions of conventional coupled-cluster theory that are exact for four electrons in four orbitals (PQ) and six electrons in six orbitals (PH), but that can also be applied to much larger systems. PQ and PH have storage requirements that scale as the square, and as the cube of the numbermore » of active electrons, respectively, and exhibit quartic scaling of the computational effort for large systems. Applications of the new implementations are presented for full-valence calculations on linear polyenes (C nH n+2), which highlight the excellent computational scaling of the present implementations that can routinely handle active spaces of hundreds of electrons. The accuracy of the models is studied in the π space of the polyenes, in hydrogen chains (H 50), and in the π space of polyacene molecules. In all cases, the results compare favorably to density matrix renormalization group values. With the novel implementation of PQ, active spaces of 140 electrons in 140 orbitals can be solved in a matter of minutes on a single core workstation, and the relatively low polynomial scaling means that very large systems are also accessible using parallel computing.« less

  1. Cost-effective description of strong correlation: Efficient implementations of the perfect quadruples and perfect hextuples models

    NASA Astrophysics Data System (ADS)

    Lehtola, Susi; Parkhill, John; Head-Gordon, Martin

    2016-10-01

    Novel implementations based on dense tensor storage are presented for the singlet-reference perfect quadruples (PQ) [J. A. Parkhill et al., J. Chem. Phys. 130, 084101 (2009)] and perfect hextuples (PH) [J. A. Parkhill and M. Head-Gordon, J. Chem. Phys. 133, 024103 (2010)] models. The methods are obtained as block decompositions of conventional coupled-cluster theory that are exact for four electrons in four orbitals (PQ) and six electrons in six orbitals (PH), but that can also be applied to much larger systems. PQ and PH have storage requirements that scale as the square, and as the cube of the number of active electrons, respectively, and exhibit quartic scaling of the computational effort for large systems. Applications of the new implementations are presented for full-valence calculations on linear polyenes (CnHn+2), which highlight the excellent computational scaling of the present implementations that can routinely handle active spaces of hundreds of electrons. The accuracy of the models is studied in the π space of the polyenes, in hydrogen chains (H50), and in the π space of polyacene molecules. In all cases, the results compare favorably to density matrix renormalization group values. With the novel implementation of PQ, active spaces of 140 electrons in 140 orbitals can be solved in a matter of minutes on a single core workstation, and the relatively low polynomial scaling means that very large systems are also accessible using parallel computing.

  2. Experimental investigation of the unsteady response of premixed flame fronts to acoustic pressure waves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wangher, Athena; Searby, Geoff; Quinard, Joel

    Using OH{sup *} chemiluminescence, we measure the experimental unsteady response of a 1-D premixed flame to an acoustic pressure wave for a range of frequencies below and above the inverse of the flame transit time. We find that the response is positive and, at low frequency, the order of magnitude is comparable with existing theoretical analyses. However, if it is assumed that the chemiluminescence is proportional to the mass consumption rate, despite some uncertainty in the interpretation of the chemiluminescence signal we find that the frequency dependence of the measured response is not compatible with the predictions of the standardmore » flame model for one-step Arrhenius kinetics. A better, but not perfect, correlation is obtained for the heat release rate. We conclude that the standard model does not provide an adequate description of the unsteady response of real flames and that it is necessary to investigate more realistic chemical models. (author)« less

  3. Jack-of-all-trades effects drive biodiversity–ecosystem multifunctionality relationships in European forests

    PubMed Central

    van der Plas, Fons; Manning, Peter; Allan, Eric; Scherer-Lorenzen, Michael; Verheyen, Kris; Wirth, Christian; Zavala, Miguel A.; Hector, Andy; Ampoorter, Evy; Baeten, Lander; Barbaro, Luc; Bauhus, Jürgen; Benavides, Raquel; Benneter, Adam; Berthold, Felix; Bonal, Damien; Bouriaud, Olivier; Bruelheide, Helge; Bussotti, Filippo; Carnol, Monique; Castagneyrol, Bastien; Charbonnier, Yohan; Coomes, David; Coppi, Andrea; Bastias, Cristina C.; Muhie Dawud, Seid; De Wandeler, Hans; Domisch, Timo; Finér, Leena; Gessler, Arthur; Granier, André; Grossiord, Charlotte; Guyot, Virginie; Hättenschwiler, Stephan; Jactel, Hervé; Jaroszewicz, Bogdan; Joly, François-Xavier; Jucker, Tommaso; Koricheva, Julia; Milligan, Harriet; Müller, Sandra; Muys, Bart; Nguyen, Diem; Pollastrini, Martina; Raulund-Rasmussen, Karsten; Selvi, Federico; Stenlid, Jan; Valladares, Fernando; Vesterdal, Lars; Zielínski, Dawid; Fischer, Markus

    2016-01-01

    There is considerable evidence that biodiversity promotes multiple ecosystem functions (multifunctionality), thus ensuring the delivery of ecosystem services important for human well-being. However, the mechanisms underlying this relationship are poorly understood, especially in natural ecosystems. We develop a novel approach to partition biodiversity effects on multifunctionality into three mechanisms and apply this to European forest data. We show that throughout Europe, tree diversity is positively related with multifunctionality when moderate levels of functioning are required, but negatively when very high function levels are desired. For two well-known mechanisms, ‘complementarity' and ‘selection', we detect only minor effects on multifunctionality. Instead a third, so far overlooked mechanism, the ‘jack-of-all-trades' effect, caused by the averaging of individual species effects on function, drives observed patterns. Simulations demonstrate that jack-of-all-trades effects occur whenever species effects on different functions are not perfectly correlated, meaning they may contribute to diversity–multifunctionality relationships in many of the world's ecosystems. PMID:27010076

  4. Jack-of-all-trades effects drive biodiversity-ecosystem multifunctionality relationships in European forests.

    PubMed

    van der Plas, Fons; Manning, Peter; Allan, Eric; Scherer-Lorenzen, Michael; Verheyen, Kris; Wirth, Christian; Zavala, Miguel A; Hector, Andy; Ampoorter, Evy; Baeten, Lander; Barbaro, Luc; Bauhus, Jürgen; Benavides, Raquel; Benneter, Adam; Berthold, Felix; Bonal, Damien; Bouriaud, Olivier; Bruelheide, Helge; Bussotti, Filippo; Carnol, Monique; Castagneyrol, Bastien; Charbonnier, Yohan; Coomes, David; Coppi, Andrea; Bastias, Cristina C; Muhie Dawud, Seid; De Wandeler, Hans; Domisch, Timo; Finér, Leena; Gessler, Arthur; Granier, André; Grossiord, Charlotte; Guyot, Virginie; Hättenschwiler, Stephan; Jactel, Hervé; Jaroszewicz, Bogdan; Joly, François-Xavier; Jucker, Tommaso; Koricheva, Julia; Milligan, Harriet; Müller, Sandra; Muys, Bart; Nguyen, Diem; Pollastrini, Martina; Raulund-Rasmussen, Karsten; Selvi, Federico; Stenlid, Jan; Valladares, Fernando; Vesterdal, Lars; Zielínski, Dawid; Fischer, Markus

    2016-03-24

    There is considerable evidence that biodiversity promotes multiple ecosystem functions (multifunctionality), thus ensuring the delivery of ecosystem services important for human well-being. However, the mechanisms underlying this relationship are poorly understood, especially in natural ecosystems. We develop a novel approach to partition biodiversity effects on multifunctionality into three mechanisms and apply this to European forest data. We show that throughout Europe, tree diversity is positively related with multifunctionality when moderate levels of functioning are required, but negatively when very high function levels are desired. For two well-known mechanisms, 'complementarity' and 'selection', we detect only minor effects on multifunctionality. Instead a third, so far overlooked mechanism, the 'jack-of-all-trades' effect, caused by the averaging of individual species effects on function, drives observed patterns. Simulations demonstrate that jack-of-all-trades effects occur whenever species effects on different functions are not perfectly correlated, meaning they may contribute to diversity-multifunctionality relationships in many of the world's ecosystems.

  5. Up-Close Look at 'Bread-Basket'

    NASA Technical Reports Server (NTRS)

    2004-01-01

    NASA's Mars Exploration Rover Spirit took this image with its front hazard-avoidance camera on sol 175 (June 30, 2004). It captures the instrument deployment device in perfect position as the rover uses its microscopic imager to get an up-close look at the rock target 'Bread-Basket.'

  6. The Eating and Drinking Ability Classification System: concurrent validity and reliability in children with cerebral palsy.

    PubMed

    Tschirren, Lea; Bauer, Susanne; Hanser, Chiara; Marsico, Petra; Sellers, Diane; van Hedel, Hubertus J A

    2018-06-01

    As there is little evidence for concurrent validity of the Eating and Drinking Ability Classification System (EDACS), this study aimed to determine its concurrent validity and reliability in children and adolescents with cerebral palsy (CP). After an extensive translation procedure, we applied the German language version to 52 participants with CP (30 males, 22 females, mean age 9y 7mo [SD 4y 2mo]). We correlated (Kendall's tau or K τ ) the EDACS levels with the Bogenhausener Dysphagiescore (BODS), and the EDACS level of assistance with the Manual Ability Classification System (MACS) and the item 'eating' of the Functional Independence Measure for Children (WeeFIM). We further quantified the interrater reliability between speech and language therapists (SaLTs) and between SaLTs and parents with Kappa (κ). The EDACS levels correlated highly with the BODS (K τ =0.79), and the EDACS level of assistance correlated highly with the MACS (K τ =0.73) and WeeFIM eating item (K τ =-0.80). Interrater reliability proved almost perfect between SaLTs (EDACS: κ=0.94; EDACS level of assistance: κ=0.89) and SaLTs and parents (EDACS: κ=0.82; EDACS level of assistance: κ=0.89). The EDACS levels and level of assistance seem valid and showed almost perfect interrater reliability when classifying eating and drinking problems in children and adolescents with CP. The Eating and Drinking Ability Classification System (EDACS) correlates well with a dysphagia score. The EDACS level of assistance proves valid. The German version of EDACS is highly reliable. EDACS correlates moderately to highly with other classification systems. © 2018 Mac Keith Press.

  7. Killed by Police: Validity of Media-Based Data and Misclassification of Death Certificates in Massachusetts, 2004-2016.

    PubMed

    Feldman, Justin M; Gruskin, Sofia; Coull, Brent A; Krieger, Nancy

    2017-10-01

    To assess the validity of demographic data reported in news media-based data sets for persons killed by police in Massachusetts (2004-2016) and to evaluate misclassification of these deaths in vital statistics mortality data. We identified 84 deaths resulting from police intervention in 4 news media-based data sources (WGBH News, Fatal Encounters, The Guardian, and The Washington Post) and, via record linkage, conducted matched-pair analyses with the Massachusetts mortality data. Compared with death certificates, there was near-perfect correlation for age in all sources (Pearson r > 0.99) and perfect concordance for gender. Agreement for race/ethnicity ranged from perfect (The Counted and The Washington Post) to high (Fatal Encounters Cohen's κ = 0.92). Among the 78 decedents for whom finalized International Classification of Diseases, 10th Revision (ICD-10), codes were available, 59 (75.6%) were properly classified as "deaths due to legal intervention." In Massachusetts, the 4 media-based sources on persons killed by police provide valid demographic data. Misclassification of deaths due to legal intervention in the mortality data does, however, remain a problem. Replication of the study in other states and nationally is warranted.

  8. Limitations of correlation-based redatuming methods

    NASA Astrophysics Data System (ADS)

    Barrera P, D. F.; Schleicher, J.; van der Neut, J.

    2017-12-01

    Redatuming aims to correct seismic data for the consequences of an acquisition far from the target. That includes the effects of an irregular acquisition surface and of complex geological structures in the overburden such as strong lateral heterogeneities or layers with low or very high velocity. Interferometric techniques can be used to relocate sources to positions where only receivers are available and have been used to move acquisition geometries to the ocean bottom or transform data between surface-seismic and vertical seismic profiles. Even if no receivers are available at the new datum, the acquisition system can be relocated to any datum in the subsurface to which the propagation of waves can be modeled with sufficient accuracy. By correlating the modeled wavefield with seismic surface data, one can carry the seismic acquisition geometry from the surface closer to geologic horizons of interest. Specifically, we show the derivation and approximation of the one-sided seismic interferometry equation for surface-data redatuming, conveniently using Green’s theorem for the Helmholtz equation with density variation. Our numerical examples demonstrate that correlation-based single-boundary redatuming works perfectly in a homogeneous overburden. If the overburden is inhomogeneous, primary reflections from deeper interfaces are still repositioned with satisfactory accuracy. However, in this case artifacts are generated as a consequence of incorrectly redatumed overburden multiples. These artifacts get even worse if the complete wavefield is used instead of the direct wavefield. Therefore, we conclude that correlation-based interferometric redatuming of surface-seismic data should always be applied using direct waves only, which can be approximated with sufficient quality if a smooth velocity model for the overburden is available.

  9. The Sagittarius tidal stream as a gravitationnal experiment in the Milky Way

    NASA Astrophysics Data System (ADS)

    Thomas, G. F.; Famaey, B.; Ibata, R.; Lüghausen, F.; Kroupa, P.

    2015-12-01

    Modified Newtonian Dynamics (MOND or Milgromian dynamics) gives a successful description of many galaxy properties that are hard to understand in the classical framework. The rotation curves of spiral galaxies are, for instance, perfectly reproduced and understood within this framework. Nevertheless, rotation curves only trace the potential in the galactic plane, and it is thus useful to test the shape of the potential outside the plane. Here we use the Sagittarius tidal stream as a gravitational experiment in the Milky Way, in order to check whether MOND can explain both its characteristics and those of the remnant dwarf spheroidal galaxy progenitor. We show that a MOND model of the Sagittarius stream can both perfectly reproduce the observed positions of stars in the stream, and even more strikingly, perfectly reproduce the observed properties of the remnant. Nevertheless, this first model does not reproduce well the observed radial velocities, which could be a signature of a rotating component in the progenitor or of the presence of a massive hot gaseous halo around the Milky Way.

  10. Risk factors for Kaposi's sarcoma in human immunodeficiency virus patients after initiation of antiretroviral therapy: A nested case-control study in Kenya.

    PubMed

    Lupia, Rodgers; Wabuyia, Peter B; Otiato, Peter; Fang, Chi-Tai; Tsai, Feng-Jen

    2017-12-01

    This study aimed to evaluate the association between highly active antiretroviral therapy (HAART) adherence and development of Kaposi's sarcoma (KS) in human immunodeficiency virus (HIV)/AIDS patients. We conducted a retrospective nested case-control study of 165 participants (33 cases and 132 controls) receiving HAART care at Maseno Hospital, Kenya, from January 2005 to October 2013. Cases were HIV-positive adults with KS, who were matched with controls in a ratio of 1:4 based on age (±5 years of each case), sex, and KS diagnosis date. Perfect adherence to HAART was assessed on every clinic visit by patients' self-reporting and pill counts. Chi-square tests were performed to compare socioeconomic and clinical statuses between cases and controls. A conditional logistic regression was used to assess the effects of perfect adherence to HAART, the latest CD4 count, education level, distance to health-care facility, initial World Health Organization stage, and number of regular sexual partners on the development of KS. Only 63.6% participants reported perfect adherence, and the control group had a significantly higher percentage of perfect adherence (75.0%) than did cases (18.2%). After adjustment for potential imbalances in the baseline and clinical characteristics, patients with imperfect HAART adherence had 20-times greater risk of developing KS than patients with perfect HAART adherence [hazard ratios: 21.0, 95% confidence interval: 4.2-105.1]. Patients with low latest CD4 count (≤350 cells/mm 3 ) had a seven-times greater risk of developing KS than did their counterparts (HRs: 7.1, 95% CI: 1.4-36.2). Imperfect HAART adherence and low latest CD4 count are significantly associated with KS development. Copyright © 2015. Published by Elsevier B.V.

  11. Spanish translation and validation of four short pelvic floor disorders questionnaires.

    PubMed

    Treszezamsky, Alejandro D; Karp, Deborah; Dick-Biascoechea, Madeline; Ehsani, Nazanin; Dancz, Christina; Montoya, T Ignacio; Olivera, Cedric K; Smith, Aimee L; Cardenas, Rosa; Fashokun, Tola; Bradley, Catherine S

    2013-04-01

    Globally, Spanish is the primary language for 329 million people; however, most urogynecologic questionnaires are available in English. We set out to develop valid Spanish translations of the Questionnaire for Urinary Incontinence Diagnosis (QUID), the Three Incontinence Questions (3IQ), and the short Pelvic Floor Distress Inventory (PFDI-20) and Pelvic Floor Impact Questionnaire (PFIQ-7). The TRAPD method (translation, review, adjudication, pretesting, and documentation) was used for translation. Eight native Spanish-speaking translators developed Spanish versions collaboratively. These were pretested with cognitive interviews and revised until optimal. For validation, bilingual patients at seven clinics completed Spanish and English questionnaire versions in randomized order. Participants completed a second set of questionnaires later. The Spanish versions' internal consistency and reliability and Spanish-English agreement were measured using Cronbach's alpha, weighted kappa, and intraclass correlation coefficients. A total of 78 subjects were included; 94.9 % self-identified as Hispanic and 73.1 % spoke Spanish as their primary language. The proportion of per-item missing responses was similar in both languages (median 1.3 %). Internal consistency for Spanish PFDI-20 subscales was acceptable to good and for PFIQ-7 and QUID excellent. Test-retest reliability per item was moderate to near perfect for PFDI-20, substantial to near perfect for PFIQ-7 and 3IQ, and substantial for QUID. Spanish-English agreement for individual items was substantial to near perfect for all questionnaires (kappa range 0.64-0.95) and agreement for PFDI-20, PFIQ-7, and QUID subscales scores was high [intraclass correlation coefficient (ICC) range 0.92-0.99]. We obtained valid Spanish translations of the PFDI-20, PFIQ-7, QUID, and 3IQ. These results support their use as clinical and research assessment tools in Spanish-speaking populations.

  12. Evaluation of Patients’ Rights Observance According to Patients’ Rights Charter in Educational Hospitals Affiliated to Mashhad University of Medical Sciences: Medical Staffs’ Views

    PubMed Central

    Sabzevari, Alireza; Kiani, Mohammad Ali; Saeidi, Masumeh; Jafari, Seyed Ali; Kianifar, Hamidreza; Ahanchian, Hamid; Jarahi, Lida; Zakerian, Mohsen

    2016-01-01

    Introduction To supply quality services and healthcare, it is evident that medical ethics and patients’ rights, while providing medical and healthcare services need to be observed. This study was conducted to evaluate observance of the Patients’ Rights Charter among medical staff of educational hospitals affiliated to Mashhad University of Medical Sciences. Methods This cross-sectional study was conducted in four educational hospitals in Mashhad on eighty physicians, nurses, nurse aids and medical students. Data were collected using a two-part inventory of patients’ rights, including demographic data and inventory of patients’ rights observance. Data analysis was conducted using SPSS-16 as well as descriptive statistics, independent t-test, chi-square, Spearman correlation coefficient and Pearson correlation. Results Mean age of subjects was 36.3±8.3. Observance of human rights was perfect by 84.4 percent of subjects. The highest amount of observance of patients’ rights was related to the area of respecting patients’ privacy and observing the principle of confidentiality, which was evaluated to be perfect by all subjects (100%). The lowest value of patients’ rights observance was related to presenting appropriate and adequate information for patients, which was perfect among 48.1% of subjects. There was no significant relation between personal details (age, gender, education and career) and observance of patients’ rights (p>0.05). Conclusion Although in this study, the observance of patients’ rights by medical staff is optimal in most areas, the area of providing appropriate and adequate information needs to be promoted. Therefore, it is suggested that more stringent regulatory policies be compiled and implemented to the items of Patients’ Rights Charter along with training courses, to strengthen medical staff’s awareness in this regard. PMID:27957310

  13. Do Recognition and Priming Index a Unitary Knowledge Base? Comment on Shanks et al. (2003)

    ERIC Educational Resources Information Center

    Runger, Dennis; Nagy, Gabriel; Frensch, Peter A.

    2009-01-01

    Whether sequence learning entails a single or multiple memory systems is a moot issue. Recently, D. R. Shanks, L. Wilkinson, and S. Channon advanced a single-system model that predicts a perfect correlation between true (i.e., error free) response time priming and recognition. The Shanks model is contrasted with a dual-process model that…

  14. Potential Predictability of U.S. Summer Climate with "Perfect" Soil Moisture

    NASA Technical Reports Server (NTRS)

    Yang, Fanglin; Kumar, Arun; Lau, K.-M.

    2004-01-01

    The potential predictability of surface-air temperature and precipitation over the United States continent was assessed for a GCM forced by observed sea surface temperatures and an estimate of observed ground soil moisture contents. The latter was obtained by substituting the GCM simulated precipitation, which is used to drive the GCM's land-surface component, with observed pentad-mean precipitation at each time step of the model's integration. With this substitution, the simulated soil moisture correlates well with an independent estimate of observed soil moisture in all seasons over the entire US continent. Significant enhancements on the predictability of surface-air temperature and precipitation were found in boreal late spring and summer over the US continent. Anomalous pattern correlations of precipitation and surface-air temperature over the US continent in the June-July-August season averaged for the 1979-2000 period increased from 0.01 and 0.06 for the GCM simulations without precipitation substitution to 0.23 and 0.3 1, respectively, for the simulations with precipitation substitution. Results provide an estimate for the limits of potential predictability if soil moisture variability is to be perfectly predicted. However, this estimate may be model dependent, and needs to be substantiated by other modeling groups.

  15. Confirmatory Factor Analysis of the Finnish Job Content Questionnaire (JCQ) in 590 Professional Musicians.

    PubMed

    Vastamäki, Heidi; Vastamäki, Martti; Laimi, Katri; Saltychev, Michail

    2017-07-01

    Poorly functioning work environments may lead to dissatisfaction for the employees and financial loss for the employers. The Job Content Questionnaire (JCQ) was designed to measure social and psychological characteristics of work environments. To investigate the factor construct of the Finnish 14-item version of JCQ when applied to professional orchestra musicians. In a cross-sectional survey, the questionnaire was sent by mail to 1550 orchestra musicians and students. 630 responses were received. Full data were available for 590 respondents (response rate 38%).The questionnaire also contained questions on demographics, job satisfaction, health status, health behaviors, and intensity of playing music. Confirmatory factor analysis of the 2-factor model of JCQ was conducted. Of the 5 estimates, JCQ items in the "job demand" construct, the "conflicting demands" (question 5) explained most of the total variance in this construct (79%) demonstrating almost perfect correlation of 0.63. In the construct of "job control," "opinions influential" (question 10) demonstrated a perfect correlation index of 0.84 and the items "little decision freedom" (question 14) and "allows own decisions" (question 6) showed substantial correlations of 0.77 and 0.65. The 2-factor model of the Finnish 14-item version of JCQ proposed in this study fitted well into the observed data. The "conflicting demands," "opinions influential," "little decision freedom," and "allows own decisions" items demonstrated the strongest correlations with latent factors suggesting that in a population similar to the studied one, especially these items should be taken into account when observed in the response of a population.

  16. Faculty and the Epistomological Revolution.

    ERIC Educational Resources Information Center

    Greeley, Andrew M.

    The suggestion that academic professions ought to be treated as games and that graduate school training should consist of preparation in gamesmanship is in this author's viewpoint, perfectly in keeping with the epistomological revolution. The literature of the 1960's which criticized the scientific world-view is reviewed. Three positions that…

  17. Correlations in Scattered X-Ray Laser Pulses Reveal Nanoscale Structural Features of Viruses

    NASA Astrophysics Data System (ADS)

    Kurta, Ruslan P.; Donatelli, Jeffrey J.; Yoon, Chun Hong; Berntsen, Peter; Bielecki, Johan; Daurer, Benedikt J.; DeMirci, Hasan; Fromme, Petra; Hantke, Max Felix; Maia, Filipe R. N. C.; Munke, Anna; Nettelblad, Carl; Pande, Kanupriya; Reddy, Hemanth K. N.; Sellberg, Jonas A.; Sierra, Raymond G.; Svenda, Martin; van der Schot, Gijs; Vartanyants, Ivan A.; Williams, Garth J.; Xavier, P. Lourdu; Aquila, Andrew; Zwart, Peter H.; Mancuso, Adrian P.

    2017-10-01

    We use extremely bright and ultrashort pulses from an x-ray free-electron laser (XFEL) to measure correlations in x rays scattered from individual bioparticles. This allows us to go beyond the traditional crystallography and single-particle imaging approaches for structure investigations. We employ angular correlations to recover the three-dimensional (3D) structure of nanoscale viruses from x-ray diffraction data measured at the Linac Coherent Light Source. Correlations provide us with a comprehensive structural fingerprint of a 3D virus, which we use both for model-based and ab initio structure recovery. The analyses reveal a clear indication that the structure of the viruses deviates from the expected perfect icosahedral symmetry. Our results anticipate exciting opportunities for XFEL studies of the structure and dynamics of nanoscale objects by means of angular correlations.

  18. Detection of periodicity based on independence tests - III. Phase distance correlation periodogram

    NASA Astrophysics Data System (ADS)

    Zucker, Shay

    2018-02-01

    I present the Phase Distance Correlation (PDC) periodogram - a new periodicity metric, based on the Distance Correlation concept of Gábor Székely. For each trial period, PDC calculates the distance correlation between the data samples and their phases. PDC requires adaptation of the Székely's distance correlation to circular variables (phases). The resulting periodicity metric is best suited to sparse data sets, and it performs better than other methods for sawtooth-like periodicities. These include Cepheid and RR-Lyrae light curves, as well as radial velocity curves of eccentric spectroscopic binaries. The performance of the PDC periodogram in other contexts is almost as good as that of the Generalized Lomb-Scargle periodogram. The concept of phase distance correlation can be adapted also to astrometric data, and it has the potential to be suitable also for large evenly spaced data sets, after some algorithmic perfection.

  19. Mean-square angle-of-arrival difference between two counter-propagating spherical waves in the presence of atmospheric turbulence.

    PubMed

    Chen, Chunyi; Yang, Huamin; Tong, Shoufeng; Lou, Yan

    2015-09-21

    The mean-square angle-of-arrival (AOA) difference between two counter-propagating spherical waves in atmospheric turbulence is theoretically formulated. Closed-form expressions for the path weighting functions are obtained. It is found that the diffraction and refraction effects of turbulent cells make negative and positive contributions to the mean-square AOA difference, respectively, and the turbulent cells located at the midpoint of the propagation path have no contributions to the mean-square AOA difference. If the mean-square AOA difference is separated into the refraction and diffraction parts, the refraction part always dominates the diffraction one, and the ratio of the diffraction part to the refraction one is never larger than 0.5 for any turbulence spectrum. Based on the expressions for the mean-square AOA difference, formulae for the correlation coefficient between the angles of arrival of two counter-propagating spherical waves in atmospheric turbulence are derived. Numerical calculations are carried out by considering that the turbulence spectrum has no path dependence. It is shown that the mean-square AOA difference always approximates to the variance of AOA fluctuations. It is found that the correlation coefficient between the angles of arrival in the x or y direction of two counter-propagating spherical waves ranges from 0.46 to 0.5, implying that the instantaneous angles of arrival of two counter-propagating spherical waves in atmospheric turbulence are far from being perfectly correlated even when the turbulence spectrum does not vary along the path.

  20. Shear Wave Structure in the Lithosphere of Texas from Ambient Noise Tomography

    NASA Astrophysics Data System (ADS)

    Yao, Y.; Li, A.

    2014-12-01

    Texas contains several distinct tectonic provinces, the Laurentia craton, the Ouachita belt, and the Gulf coastal plain. Although numerous geophysical experiments have been conducted in Texas for petroleum exploration, the lithosphere structure of Texas has not been well studied. We present here the Texas-wide shear wave structure using seismic ambient noise data recorded at 87 stations from the Transportable Array of the USArray between March 2010 and February 2011. Rayleigh wave phase velocities between pairs of stations are obtained by cross-correlating long ambient noise sequences and are used to develop phase velocity maps from 6 to 40 s. These measured phase velocities are used to construct 1-D and 3-D shear wave velocity models, which consist of four crust layers and one upper mantle layer. Shear wave velocity maps reveal a close correlation with major geological features. From the surface to 25 km depth, Positive anomalies coincide with the Laurentia craton, and negative anomalies coincide with the continental margin. The boundary of positive-negative anomaly perfectly matches the Ouachita belt. The Llano Uplift is imaged as the highest velocity through the mid-crust because the igneous rock forming the uplift has faster seismic velocity than the normal continental crust. Similarly, three small high-velocity areas exist beneath the Waco Uplift, Devils River Uplift, and Benton Uplift, even though surface geological traces are absent in these areas. The lowest velocity at the shallow crust appears in northeastern and southeastern Texas separated by the San Marcos Arch, correlating with thick sediment layers. An exceptional low velocity is imaged in southernmost Texas in the lower crust and upper mantle, probably caused by subducted wet oceanic crust before the rifting in the Gulf of Mexico. In the uppermost mantle, positive shear wave anomalies extend southeastward from the Ouachita belt to the Gulf coast, likely evidencing the subducted oceanic lithosphere during the Ouachita orogeny. This observation need be further tested using long period surface wave dispersions from earthquakes, which help to improve model resolution in the upper mantle.

  1. An artificial intelligence approach to lithostratigraphic correlation using geophysical well logs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olea, R.A.; Davis, J.C.

    1986-01-01

    Computer programs for lithostratigraphic correlation of well logs have achieved limited success. Their algorithms are based on an oversimplified view of the manual process used by analysts to establish geologically correct correlations. The programs experience difficulties if the correlated rocks deviate from an ideal geometry of perfectly homogeneous, parallel layers of infinite extent. Artificial intelligence provides a conceptual basis for formulating the task of lithostratigraphic correlation, leading to more realistic procedures. A prototype system using the ''production rule'' approach of expert systems successfully correlates well logs in areas of stratigraphic complexity. Two digitized logs are used per well, one formore » curve matching and the other for lithologic comparison. The software has been successfully used to correlate more than 100,000 ft (30 480 m) of section, through clastic sequences in Louisiana and through carbonate sequences in Kansas. Correlations have been achieved even in the presence of faults, unconformities, facies changes, and lateral variations in bed thickness.« less

  2. Digital Image Quality And Interpretability: Database And Hardcopy Studies

    NASA Astrophysics Data System (ADS)

    Snyder, H. L.; Maddox, M. E.; Shedivy, D. I.; Turpin, J. A.; Burke, J. J.; Strickland, R. N.

    1982-02-01

    Two hundred fifty transparencies, displaying a new digital database consisting of 25 degraded versions (5 blur levels x 5 noise levels) of each of 10 digitized, first-generation positive transparencies, were used in two experiments involving 15 trained military photointer-preters. Each image is 86 mm square and represents 40962 8-bit pixels. In the "interpretation" experiment, each photointerpreter (judge) spent approximately two days extracting essential elements of information (EEls) from one degraded version of each scene at a constant Gaussian blur level (FWHM = 40, 84, or 322 Am). In the scaling experiment, each judge assigned a numerical value to each of the 250 images, according to its perceived position on a 10-point NATO-standardized scale (0 = useless through 9 = nearly perfect), to the nearest 0.1 unit. Eighty-eight of the 100 possible values were used by the judges, indicating that 62 categories, based on the Shannon-Wiener measure of information, are needed to scale these hardcopy images. The overall correlation between the scaling and interpretation results was 0.9. Though the main effect of blur was not statistically significant in the interpretation experiment, that of noise was significant, and all main factors (blur, noise, scene, order of battle) and most interactions were statistically significant in the scaling experiment.

  3. Quality Metrics Of Digitally Derived Imagery And Their Relation To Interpreter Performance

    NASA Astrophysics Data System (ADS)

    Burke, James J.; Snyder, Harry L.

    1981-12-01

    Two hundred-fifty transparencies, displaying a new digital database consisting of 25 degraded versions (5 blur levels x 5 noise levels) of each of 10 digitized, first-generation positive transparencies, were used in two experiments involving 15 trained military photo-interpreters. Each image is 86 mm square and represents 40962 8-bit pixels. In the "interpretation" experiment, each photo-interpreter (judge) spent approximately two days extracting Essential Elements of Information (EEI's) from one degraded version of each scene at a constant blur level (FWHM = 40, 84 or 322 μm). In the scaling experiment, each judge assigned a numerical value to each of the 250 images, according to its perceived position on a 10-point NATO-standardized scale (0 = useless through 9 = nearly perfect), to the nearest 0.1 unit. Eighty-eight of the 100 possible values were used by the judges, indicating that 62 categories are needed to scale these hardcopy images. The overall correlation between the scaling and interpretation results was 0.9. Though the main effect of blur was not significant (p = 0.146) in the interpretation experiment, that of noise was significant (p = 0.005), and all main factors (blur, noise, scene, order of battle) and most interactions were statistically significant in the scaling experiment.

  4. Model to Test Electric Field Comparisons in a Composite Fairing Cavity

    NASA Technical Reports Server (NTRS)

    Trout, Dawn; Burford, Janessa

    2012-01-01

    Evaluating the impact of radio frequency transmission in vehicle fairings is important to sensitive spacecraft. This study shows cumulative distribution function (CDF) comparisons of composite . a fairing electromagnetic field data obtained by computational electromagnetic 3D full wave modeling and laboratory testing. This work is an extension of the bare aluminum fairing perfect electric conductor (PEC) model. Test and model data correlation is shown.

  5. Model to Test Electric Field Comparisons in a Composite Fairing Cavity

    NASA Technical Reports Server (NTRS)

    Trout, Dawn H.; Burford, Janessa

    2013-01-01

    Evaluating the impact of radio frequency transmission in vehicle fairings is important to sensitive spacecraft. This study shows cumulative distribution function (CDF) comparisons of composite a fairing electromagnetic field data obtained by computational electromagnetic 3D full wave modeling and laboratory testing. This work is an extension of the bare aluminum fairing perfect electric conductor (PEC) model. Test and model data correlation is shown.

  6. Ultracold bosons in a one-dimensional optical lattice chain: Newton's cradle and Bose enhancement effect

    NASA Astrophysics Data System (ADS)

    Wang, Ji-Guo; Yang, Shi-Jie

    2017-05-01

    We study a model to realize the long-distance correlated tunneling of ultracold bosons in a one-dimensional optical lattice chain. The model reveals the behavior of a quantum Newton's cradle, which is the perfect transfer between two macroscopic quantum states. Due to the Bose enhancement effect, we find that the resonantly tunneling through a Mott domain is greatly enhanced.

  7. Alcohol Use Disorders Negatively Influence Antiretroviral Medication Adherence Among Men Who Have Sex with Men in Peru

    PubMed Central

    Ferro, Enrico G.; Weikum, Damian; Vagenas, Panagiotis; Copenhaver, Michael M.; Gonzales, Pedro; Peinado, Jesus; Lama, Javier R.; Sanchez, Jorge; Altice, Frederick L.

    2014-01-01

    Objective As international guidelines increase access to antiretroviral therapy (ART) globally, ART adherence becomes increasingly important to achieve HIV treatment as prevention (TasP) goals. In the concentrated HIV epidemic among men who have sex with men (MSM) and transgendered women (TGW) in Lima, Peru, the independent correlates of ART non-adherence were examined to inform treatment intervention priorities. Design Cross sectional survey of HIV-infected MSM and TGW who are engaged in clinical care in Lima, Peru. Methods From June to August 2012, 302 HIV-infected Peruvian MSM/TGW from three clinical care sites were recruited using convenience sampling to participate in a cross-sectional computer-assisted adherence survey. Several standardized screening measures associated with ART non-adherence were examined in order to determine the independent correlates of optimal (≥90%) and perfect (100%) adherence, which were assessed using logistic regression. Results Of the 302 participants recruited, 263 (87.1%) were prescribed ART. Among those prescribed ART, 229 (87.1%) reported optimal and 146 (55.5%) reported perfect adherence. The prevalence of alcohol use disorders (AUD; 43.2%), alcohol dependence (5.3%), recent drug use (6.0%) and depression (44.5%) was high and most participants had some evidence of neurocognitive impairment. Meeting criteria for having an AUD and depression were collinear (p<0.001). On multivariate analysis, having an AUD was inversely related and the only independent correlate of optimal (AOR=0.427; 95% CI=0.187–0.976) and perfect (AOR=0.552; 95% CI=0.327–0.930) ART adherence. Conclusions AUDs are highly prevalent among Peruvian HIV-infected MSM and contribute significantly to ART non-adherence. These findings support the need for screening and treating underlying AUDs. In order to meet HIV TasP goals, evidence-based strategies targeting AUDs are likely to directly improve ART adherence and indirectly improve overall individual health, HIV treatment engagement and reduce transmission to sexual partners among this vulnerable and disproportionally affected population. PMID:25277252

  8. Turning Imperfection into Perfection: Some Advice for Making Psychology Indispensable in the Schools.

    ERIC Educational Resources Information Center

    Medway, Frederic J.

    Despite the field's growth, development, and maturity, in many ways the typical psychologist in the schools in little better off than a quarter century ago. Presently school psychology positions rest primarily on the shaky bedrock of financial and legislative considerations rather than perceived need. Following marketing strategies can enhance the…

  9. The intra- and inter-rater reliability of five clinical muscle performance tests in patients with and without neck pain

    PubMed Central

    2013-01-01

    Background This study investigates the reliability of muscle performance tests using cost- and time-effective methods similar to those used in clinical practice. When conducting reliability studies, great effort goes into standardising test procedures to facilitate a stable outcome. Therefore, several test trials are often performed. However, when muscle performance tests are applied in the clinical setting, clinicians often only conduct a muscle performance test once as repeated testing may produce fatigue and pain, thus variation in test results. We aimed to investigate whether cervical muscle performance tests, which have shown promising psychometric properties, would remain reliable when examined under conditions similar to those of daily clinical practice. Methods The intra-rater (between-day) and inter-rater (within-day) reliability was assessed for five cervical muscle performance tests in patients with (n = 33) and without neck pain (n = 30). The five tests were joint position error, the cranio-cervical flexion test, the neck flexor muscle endurance test performed in supine and in a 45°-upright position and a new neck extensor test. Results Intra-rater reliability ranged from moderate to almost perfect agreement for joint position error (ICC ≥ 0.48-0.82), the cranio-cervical flexion test (ICC ≥ 0.69), the neck flexor muscle endurance test performed in supine (ICC ≥ 0.68) and in a 45°-upright position (ICC ≥ 0.41) with the exception of a new test (neck extensor test), which ranged from slight to moderate agreement (ICC = 0.14-0.41). Likewise, inter-rater reliability ranged from moderate to almost perfect agreement for joint position error (ICC ≥ 0.51-0.75), the cranio-cervical flexion test (ICC ≥ 0.85), the neck flexor muscle endurance test performed in supine (ICC ≥ 0.70) and in a 45°-upright position (ICC ≥ 0.56). However, only slight to fair agreement was found for the neck extensor test (ICC = 0.19-0.25). Conclusions Intra- and inter-rater reliability ranged from moderate to almost perfect agreement with the exception of a new test (neck extensor test), which ranged from slight to moderate agreement. The significant variability observed suggests that tests like the neck extensor test and the neck flexor muscle endurance test performed in a 45°-upright position are too unstable to be used when evaluating neck muscle performance. PMID:24299621

  10. Colorstratigraphy; A New Stratigraphic Correlation Technique

    NASA Astrophysics Data System (ADS)

    Nanayakkara, N. U.; Ranasinghage, P. N.; Priyantha, C.; Abillapitiya, T.

    2016-12-01

    Here we introduce a novel stratigraphic technique namely colorstratigraphy for correlating sedimentary sequences. Minihagalkanda is about 1 km long amphitheater like sedimentary terrain, situated at the southeastern coast of Sri Lanka. It has Miocene sedimentary sequences, separated in to 10-12 m high small hillocks by erosion, and bounded by about 30 m high escarpment. Sandstone, yellowish sandy clay, greenish silty clay sequences are capped by 4-5 m limestone bed in these hillocks but not at the boundary escarpment. Stratigraphic profiles at two hillocks and the boundary escarpment, separated each other by 200-300 m, were selected to test the new colorstartigraphic correlation technique. Color reflectance (DSR) was measured at four samples in each sequence at every profile and hence altogether 36 reflectance measurements were taken using Minolta 2500D hand-held color spectrophotometer. The first-derivative of the reflectance spectra (dR/dλ) defines the "spectral shape" of the sample. Therefore, DSR data (360-740 nm) measured at 10 nm resolution were used to calculate a center-weighted, first-derivative spectra for each reflectance sample consisting of 39 channels. Particle size of each sequence was measured at all 03 profiles using laser particle size analyzer to verify the stratigraphic correlation. Mean reflectance spectrum for each sequence at all 03 profiles were plotted on the same graph for comparison. Same was done for the grain size spectrums. Discriminant function analysis was performed separately for dsr data and grain size data using a number assigned to each sedimentary sequence as the grouping variable Color spectrums of sandstone, yellowish sandy clay, and greenish silty clay sequences at all three profiles perfectly match showing clear stratigraphic correlation among these three stratigraphic profiles. Matching grain size distribution curves of the three sequence at the three profiles verify the stratigraphic correlation. Perfect 100 % discrimination of the three sequences with color reflectance data proves the accuracy of the correlation. Similar 100 % discrimination resulted with grain size data further verifies the results. Therefore, colorstratigraphy based on DSR can be introduced as a quick and easy technique for stratigraphic correlation of sedimentary sequences.

  11. Articulation and oromyofunctional behavior in children seeking orthodontic treatment.

    PubMed

    Van Lierde, K M; Luyten, A; D'haeseleer, E; Van Maele, G; Becue, L; Fonteyne, E; Corthals, P; De Pauw, G

    2015-05-01

    The purpose of this controlled study is to document articulation and oromyofunctional behavior in children seeking orthodontic treatment. In addition, relations between malocclusions, articulation, and oromyofunctional behavior are studied. The study included 56 children seeking orthodontic treatment. The control group, consisting of 54 subjects matched for age and gender, did not undergo orthodontic intervention. To determine the impact of the occlusion on speech, the Oral Health Impact Profile was used. Speech characteristics, intelligibility and several lip and tongue functions were analyzed using consensus evaluations. A significant impact of the occlusion on speech and more articulation disorders for/s,n,l,t/were found in the subjects seeking orthodontic treatment. Several other phenomena were seen more often in this group, namely more impaired lip positioning during swallowing, impaired tongue function at rest, mouth breathing, open mouth posture, lip sucking/biting, anterior tongue position at rest, and tongue thrust. Moreover, all children with a tongue thrust showed an anterior tongue position at rest. Children seeking orthodontics have articulatory and oromyofunctional disorders. To what extent a combined orthodontic and logopaedic treatment can result in optimal oral health (i.e. perfect dentofacial unit with perfect articulation) is subject for further multidisciplinary research. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  12. Extended orientational correlation study for molecular liquids containing distorted tetrahedral molecules: Application to methylene halides

    NASA Astrophysics Data System (ADS)

    Pothoczki, Szilvia; Temleitner, László; Pusztai, László

    2010-04-01

    The method of Rey [Rey, J. Chem. Phys. 126, 164506 (2007)] for describing how molecules orient toward each other in systems with perfect tetrahedral molecules is extended to the case of distorted tetrahedral molecules of c2v symmetry by means of introducing 28 subgroups. Additionally, the original analysis developed for perfect tetrahedral molecules, based on six groups, is adapted for molecules with imperfect tetrahedral shape. Deriving orientational correlation functions have been complemented with detailed analyses of dipole-dipole correlations. This way, (up to now) the most complete structure determination can be carried out for such molecular systems. In the present work, these calculations have been applied for particle configurations resulting from reverse Monte Carlo computer modeling. These particle arrangements are fully consistent with structure factors from neutron and x-ray diffraction measurements. Here we present a complex structural study for methylene halide (chloride, bromide, and iodide) molecular liquids, as possibly the best representative examples. It has been found that the most frequent orientations of molecules are of the 2:2 type over the entire distance range in these liquids. Focusing on the short range orientation, neighboring molecules turn toward each other with there "H,Y"-"H,Y" (Y: Cl, Br, I) edges, apart from CH2Cl2 where the H,H-H,Cl arrangement is the most frequent. In general, the structure of methylene chloride appears to be different from the structure of the other two liquids.

  13. Position of the prosthesis components in total ankle replacement and the effect on motion at the replaced joint.

    PubMed

    Cenni, Francesco; Leardini, Alberto; Cheli, Andrea; Catani, Fabio; Belvedere, Claudio; Romagnoli, Matteo; Giannini, Sandro

    2012-03-01

    In some cases of total ankle replacement, perfect alignment of the prosthetic components is not achieved. This study analyses the extent to which component positioning is critical for the final range of motion. Fourteen patients undergoing total ankle replacement were assessed preoperatively and postoperatively at seven and 13 months follow-up. X-ray pictures of the ankle were taken in static double leg stance, i.e. at neutral joint position, and in maximum plantarflexion and dorsiflexion. Measurements were obtained by a specially devised computer program based on anatomical reference points digitised on the radiograms. These allowed calculation of the position and orientation of the components in the sagittal and coronal planes, together with the joint range of motion. The mean range of motion was about 34 degrees at the first follow-up and maintained at the second. Tibial and talar components were more anterior than the mid-tibial shaft in 11 and nine patients, respectively. Mean inclination was about four degrees posterior for the tibial component and nearly one degree anterior for the talar component. A significantly larger range of motion was found in ankles both with the talar component located and inclined more anteriorly than the tibial. Correlation, though weak, was found between motion at the replaced ankle and possible residual subluxation and inclination of the components. However, a satisfactory range of motion was also achieved in those patients where recommended locations for the components could not be reached because of the size of the original joint deformity.

  14. Correlations in Scattered X-Ray Laser Pulses Reveal Nanoscale Structural Features of Viruses

    DOE PAGES

    Kurta, Ruslan P.; Donatelli, Jeffrey J.; Yoon, Chun Hong; ...

    2017-10-12

    We use extremely bright and ultrashort pulses from an x-ray free-electron laser (XFEL) to measure correlations in x rays scattered from individual bioparticles. This allows us to go beyond the traditional crystallography and single-particle imaging approaches for structure investigations. We employ angular correlations to recover the three-dimensional (3D) structure of nanoscale viruses from x-ray diffraction data measured at the Linac Coherent Light Source. Correlations provide us with a comprehensive structural fingerprint of a 3D virus, which we use both for model-based and ab initio structure recovery. The analyses reveal a clear indication that the structure of the viruses deviates frommore » the expected perfect icosahedral symmetry. Lastly, our results anticipate exciting opportunities for XFEL studies of the structure and dynamics of nanoscale objects by means of angular correlations.« less

  15. Strong correlation in incremental full configuration interaction

    NASA Astrophysics Data System (ADS)

    Zimmerman, Paul M.

    2017-06-01

    Incremental Full Configuration Interaction (iFCI) reaches high accuracy electronic energies via a many-body expansion of the correlation energy. In this work, the Perfect Pairing (PP) ansatz replaces the Hartree-Fock reference of the original iFCI method. This substitution captures a large amount of correlation at zero-order, which allows iFCI to recover the remaining correlation energy with low-order increments. The resulting approach, PP-iFCI, is size consistent, size extensive, and systematically improvable with increasing order of incremental expansion. Tests on multiple single bond, multiple double bond, and triple bond dissociations of main group polyatomics using double and triple zeta basis sets demonstrate the power of the method for handling strong correlation. The smooth dissociation profiles that result from PP-iFCI show that FCI-quality ground state computations are now within reach for systems with up to about 10 heavy atoms.

  16. Cooperative ordering and kinetics of cellulose nanocrystal alignment in a magnetic field

    DOE PAGES

    De France, Kevin J.; Yager, Kevin G.; Hoare, Todd; ...

    2016-07-13

    Cellulose nanocrystals (CNCs) are emerging nanomaterials that form chiral nematic liquid crystals above a critical concentration (C*) and additionally orient within electromagnetic fields. The control over CNC alignment is significant for materials processing and end use; to date, magnetic alignment has been demonstrated using only strong fields over extended or arbitrary time scales. This work investigates the effects of comparatively weak magnetic fields (0–1.2 T) and CNC concentration (1.65–8.25 wt %) on the kinetics and degree of CNC ordering using small-angle X-ray scattering. Interparticle spacing, correlation length, and orientation order parameters (η and S) increased with time and field strengthmore » following a sigmoidal profile. In a 1.2 T magnetic field for CNC suspensions above C*, partial alignment occurred in under 2 min followed by slower cooperative ordering to achieve nearly perfect alignment in under 200 min (S = –0.499 where S = –0.5 indicates perfect antialignment). At 0.56 T, nearly perfect alignment was also achieved, yet the ordering was 36% slower. Outside of a magnetic field, the order parameter plateaued at 52% alignment (S = –0.26) after 5 h, showcasing the drastic effects of relatively weak magnetic fields on CNC alignment. For suspensions below C*, no magnetic alignment was detected.« less

  17. Effects of Nonsphericity on the Behavior of Lorenz-Mie Resonances in Scattering Characteristics of Liquid-Cloud Droplets

    NASA Technical Reports Server (NTRS)

    Dlugach, Janna M.; Mishchenko, Michael I.

    2014-01-01

    By using the results of highly accurate T-matrix computations for randomly oriented oblate and prolate spheroids and Chebyshev particles with varying degrees of asphericity, we analyze the effects of a deviation of water-droplet shapes from that of a perfect sphere on the behavior of Lorenz-Mie morphology-dependent resonances of various widths. We demonstrate that the positions and profiles of the resonances can change significantly with increasing asphericity. The absolute degree of asphericity required to suppress a Lorenz-Mie resonance is approximately proportional to the resonance width. Our results imply that numerical averaging of scattering characteristics of real cloud droplets over sizes may rely on a significantly coarser size-parameter resolution than that required for ideal, perfectly spherical particles.

  18. Engineering the Complex-Valued Constitutive Parameters of Metamaterials for Perfect Absorption

    NASA Astrophysics Data System (ADS)

    Wang, Pengwei; Chen, Naibo; Tang, Chaojun; Chen, Jing; Liu, Fanxin; Sheng, Saiqian; Yan, Bo; Sui, Chenghua

    2017-04-01

    We theoretically studied how to directly engineer the constitutive parameters of metamaterials for perfect absorbers of electromagnetic waves. As an example, we numerically investigated the necessary refractive index n and extinction coefficient k and the relative permittivity ɛ and permeability μ of a metamaterial anti-reflection layer, which could cancel the reflection from a hydrogenated amorphous silicon (α-Si:H) thin film on a metal substrate, within the visible wavelength range from 300 to 800 nm. We found that the metamaterial anti-reflection layer should have a negative refractive index ( n < 0) for short-wavelength visible light but have a positive refractive index ( n > 0) for long-wavelength visible light. The relative permittivity ɛ and permeability μ could be fitted by the Lorentz model, which exhibited electric and magnetic resonances, respectively.

  19. A stochastic model with a low-frequency amplification feedback for the stratospheric northern annular mode

    NASA Astrophysics Data System (ADS)

    Yu, Yueyue; Cai, Ming; Ren, Rongcai

    2017-08-01

    We consider three indices to measure the polar stratospheric mass and stratospheric meridional mass circulation variability: anomalies of (1) total mass in the polar stratospheric cap (60-90°N, above the isentropic surface 400 K, PSM), (2) total adiabatic mass transport across 60°N into the polar stratosphere cap (AMT), (3) and total diabetic mass transport across 400 K from the polar stratosphere into the troposphere below (DMT). It is confirmed that the negative stratospheric Northern Annular Mode (NAM) and PSM indices have a nearly indistinguishable temporal evolution and a similar red-noise-like spectrum with a de-correlation timescale of 4 weeks. This enables us to examine the low-frequency nature of the NAM in the framework of mass circulation, namely, d/{dt}{PSM}={AMT} - {DMT} . The DMT index tends to be positively correlated with the PSM with a red-noise-like spectrum, representing slow radiative cooling processes giving rise to a de-correlation timescale of 3-4 weeks. The AMT is nearly perfectly correlated with the day-to-day tendency of PSM, reflecting a robust quasi 90° out-of-phase relation between the AMT and PSM at all frequency bands. Variations of vertically westward tilting of planetary waves contribute mainly to the high-frequency portion of AMT. It is the wave amplitude's slow vacillation that plays the leading role in the quasi 90° out-of-phase relation between the AMT and PSM. Based on this, we put forward a linear stochastic model with a low-frequency amplification feedback from low-frequency amplitude vacillations of planetary waves to explain the amplified low-frequency response of PSM/NAM to a stochastic forcing from the westward tilting variability.

  20. Distance-to-Agreement Investigation of Tomotherapy's Bony Anatomy-Based Autoregistration and Planning Target Volume Contour-Based Optimization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Suh, Steve, E-mail: ssuh@coh.org; Schultheiss, Timothy E.

    Purpose: To compare Tomotherapy's megavoltage computed tomography bony anatomy autoregistration with the best achievable registration, assuming no deformation and perfect knowledge of planning target volume (PTV) location. Methods and Materials: Distance-to-agreement (DTA) of the PTV was determined by applying a rigid-body shift to the PTV region of interest of the prostate from its reference position, assuming no deformations. Planning target volume region of interest of the prostate was extracted from the patient archives. The reference position was set by the 6 degrees of freedom (dof)—x, y, z, roll, pitch, and yaw—optimization results from the previous study at this institution. Themore » DTA and the compensating parameters were calculated by the shift of the PTV from the reference 6-dof to the 4-dof—x, y, z, and roll—optimization. In this study, the effectiveness of Tomotherapy's 4-dof bony anatomy–based autoregistration was compared with the idealized 4-dof PTV contour-based optimization. Results: The maximum DTA (maxDTA) of the bony anatomy-based autoregistration was 3.2 ± 1.9 mm, with the maximum value of 8.0 mm. The maxDTA of the contour-based optimization was 1.8 ± 1.3 mm, with the maximum value of 5.7 mm. Comparison of Pearson correlation of the compensating parameters between the 2 4-dof optimization algorithms shows that there is a small but statistically significant correlation in y and z (0.236 and 0.300, respectively), whereas there is very weak correlation in x and roll (0.062 and 0.025, respectively). Conclusions: We find that there is an average improvement of approximately 1 mm in terms of maxDTA on the PTV going from 4-dof bony anatomy-based autoregistration to the 4-dof contour-based optimization. Pearson correlation analysis of the 2 4-dof optimizations suggests that uncertainties due to deformation and inadequate resolution account for much of the compensating parameters, but pitch variation also makes a statistically significant contribution.« less

  1. A perfectly conducting surface in electrodynamics with Lorentz symmetry breaking

    NASA Astrophysics Data System (ADS)

    Borges, L. H. C.; Barone, F. A.

    2017-10-01

    In this paper we consider a model which exhibits explicit Lorentz symmetry breaking due to the presence of a single background vector v^{μ } coupled to the gauge field. We investigate such a theory in the vicinity of a perfectly conducting plate for different configurations of v^{μ }. First we consider no restrictions on the components of the background vector and we treat it perturbatively up to second order. Next, we treat v^{μ } exactly for two special cases: the first one is when it has only components parallel to the plate, and the second one when it has a single component perpendicular to the plate. For all these configurations, the propagator for the gauge field and the interaction force between the plate and a point-like electric charge are computed. Surprisingly, it is shown that the image method is valid in our model and we argue that it is a non-trivial result. We show there arises a torque on the mirror with respect to its positioning in the background field when it interacts with a point-like charge. It is a new effect with no counterpart in theories with Lorentz symmetry in the presence of a perfect mirror.

  2. A minimalistic approach to static and dynamic electron correlations: Amending generalized valence bond method with extended random phase approximation correlation correction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chatterjee, Koushik; Jawulski, Konrad; Pastorczak, Ewa

    A perfect-pairing generalized valence bond (GVB) approximation is known to be one of the simplest approximations, which allows one to capture the essence of static correlation in molecular systems. In spite of its attractive feature of being relatively computationally efficient, this approximation misses a large portion of dynamic correlation and does not offer sufficient accuracy to be generally useful for studying electronic structure of molecules. We propose to correct the GVB model and alleviate some of its deficiencies by amending it with the correlation energy correction derived from the recently formulated extended random phase approximation (ERPA). On the examples ofmore » systems of diverse electronic structures, we show that the resulting ERPA-GVB method greatly improves upon the GVB model. ERPA-GVB recovers most of the electron correlation and it yields energy barrier heights of excellent accuracy. Thanks to a balanced treatment of static and dynamic correlation, ERPA-GVB stays reliable when one moves from systems dominated by dynamic electron correlation to those for which the static correlation comes into play.« less

  3. On Pell, Pell-Lucas, and balancing numbers.

    PubMed

    Karadeniz Gözeri, Gül

    2018-01-01

    In this paper, we derive some identities on Pell, Pell-Lucas, and balancing numbers and the relationships between them. We also deduce some formulas on the sums, divisibility properties, perfect squares, Pythagorean triples involving these numbers. Moreover, we obtain the set of positive integer solutions of some specific Pell equations in terms of the integer sequences mentioned in the text.

  4. Preliminary Findings on the Effects of Self-Referring and Evaluative Stimuli on Stimulus Equivalence Class Formation

    ERIC Educational Resources Information Center

    Merwin, Rhonda M.; Wilson, Kelly G.

    2005-01-01

    Thirty-two subjects completed 2 stimulus equivalence tasks using a matching-to-sample paradigm. One task involved direct reinforcement of conditional discriminations designed to produce derived relations between self-referring stimuli (e.g., me, myself, I) and positive evaluation words (e.g., whole, desirable, perfect). The other task was designed…

  5. Scattering Experiments at the Ipswich Electromagnetic Measurements Facility: Calibration with Perfectly Conducting Spheres,

    DTIC Science & Technology

    1983-08-01

    densities at 8. Silver, S . . op cit, pp. 182- 187. 19 __ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ the target position and, for a given target 0, the power...Mlic rowave Antennia Theory and Design. Mlitraw - Hill Hook Uomipany, Inc. , ’Newv Y rk, pp. 586-581. 8. Silve r. S . , op cit, pp. 182- 1817. 27 M

  6. Creating Cultural Capital in the Classroom: Being Perfectly Frank about Writing

    ERIC Educational Resources Information Center

    Weaven, Mary; Clifford, Rohan

    2015-01-01

    The production of writing occupies a significant place in English classrooms; it also underpins current assessment regimes. While curriculum policies emphasise the need for students to become proficient writers, scant attention has been given to the position of teachers as writers and the impact that such an omission may have on writing pedagogy.…

  7. An Inside Look at an Outside Candidate

    ERIC Educational Resources Information Center

    Vinton, Donna

    2004-01-01

    This article traces the author's emotional journey of a job search, from finding what seems to be the perfect position to being turned down for the job. It is intended to remind counselors, employers, and job seekers of the emotional side of a process that is often seen as a simple series of rational, cognitive, and carefully planned steps.

  8. Validity of EuroQOL-5D, time trade-off, and standard gamble for age-related macular degeneration in the Singapore population

    PubMed Central

    Au Eong, K G; Chan, E W; Luo, N; Wong, S H; Tan, N W H; Lim, T H; Wagle, A M

    2012-01-01

    Background/aims Utility values of age-related macular degeneration (AMD) in Asian patients are unknown. This study aims to assess utility values and construct validity of the EuroQOL-5D (EQ-5D), time trade-off (TTO), and standard gamble (SG) instruments in the Singapore multi-ethnic AMD population. Methods Cross-sectional, two-centre, institution-based study. Visual acuity (VA), clinical AMD severity, and utility scores on the EQ-5D, TTO, and SG were obtained from 338 AMD patients. VA was analysed in terms of the better-seeing eye (BEVA), worse-seeing eye (WEVA), and weighted average of both eyes (WVA). We evaluated SG on the perfect health-death (SG(death)) and binocular perfect vision-binocular blindness (SG(blindness)) scales. Construct validity was determined by testing a priorihypotheses relating the EQ-5D, TTO, and SG utility scores to VA and clinical AMD severity. Results The mean utilities on the EQ-5D, TTO, SG(death), and SG(blindness) were 0.89, 0.81, 0.86, and 0.90, respectively. EQ-5D scores correlated weakly with BEVA, WEVA, and WVA (Pearson's correlation coefficients −0.291, −0.247, and −0.305 respectively, P<0.001 for all). SG(death) and SG(blindness) demonstrated no correlation with BEVA, WEVA, or WVA (Pearson's correlation coefficients, range −0.06 to −0.125). TTO showed weak association only with WEVA and WVA (correlation coefficients −0.237, −0.228, P<0.0001), but not with BEVA (correlation coefficient −0.161). Clinical AMD severity correlated with EQ-5D and SG(death), but not with TTO and SG(blindness) (P=0.004, 0.002, 0.235, and 0.069, respectively). Conclusions AMD has a negative impact on utilities, although utility scores were high compared with Western cohorts. EQ-5D, TTO, and SG showed suboptimal construct validity, suggesting that health status utilities may not be sufficiently robust for cost-utility analyses in this population. PMID:22222257

  9. Kinematical Correlations for Higgs Boson Plus High P_{T} Jet Production at Hadron Colliders.

    PubMed

    Sun, Peng; Yuan, C-P; Yuan, Feng

    2015-05-22

    We investigate the effect of QCD resummation to kinematical correlations in the Higgs boson plus high transverse momentum (P(T)) jet events produced at hadron colliders. We show that at the complete one-loop order, the Collins-Soper-Sterman resummation formalism can be applied to derive the Sudakov form factor. We compare the singular behavior of resummation calculation to fixed order prediction in the case that a Higgs boson and high P(T) jet are produced nearly back to back in their transverse momenta, and find perfect agreement. The phenomenological importance of the resummation effect at the LHC is also demonstrated.

  10. Two-mode thermal-noise squeezing in an electromechanical resonator.

    PubMed

    Mahboob, I; Okamoto, H; Onomitsu, K; Yamaguchi, H

    2014-10-17

    An electromechanical resonator is developed in which mechanical nonlinearities can be dynamically engineered to emulate the nondegenerate parametric down-conversion interaction. In this configuration, phonons are simultaneously generated in pairs in two macroscopic vibration modes, resulting in the amplification of their motion. In parallel, two-mode thermal squeezed states are also created, which exhibit fluctuations below the thermal motion of their constituent modes as well as harboring correlations between the modes that become almost perfect as their amplification is increased. The existence of correlations between two massive phonon ensembles paves the way towards an entangled macroscopic mechanical system at the single phonon level.

  11. Benchmark quality total atomization energies of small polyatomic molecules

    NASA Astrophysics Data System (ADS)

    Martin, Jan M. L.; Taylor, Peter R.

    1997-05-01

    Successive coupled-cluster [CCSD(T)] calculations in basis sets of spdf, spdfg, and spdfgh quality, combined with separate Schwartz-type extrapolations A+B/(l+1/2)α of the self-consistent field (SCF) and correlation energies, permit the calculations of molecular total atomization energies (TAEs) with a mean absolute error of as low as 0.12 kcal/mol. For the largest molecule treated, C2H4, we find ∑D0=532.0 kcal/mol, in perfect agreement with experiment. The aug-cc-pV5Z basis set recovers on average about 99% of the valence correlation contribution to the TAE, and essentially the entire SCF contribution.

  12. Kinematical Correlations for Higgs Boson Plus High PT Jet Production at Hadron Colliders

    NASA Astrophysics Data System (ADS)

    Sun, Peng; Yuan, C.-P.; Yuan, Feng

    2015-05-01

    We investigate the effect of QCD resummation to kinematical correlations in the Higgs boson plus high transverse momentum (PT) jet events produced at hadron colliders. We show that at the complete one-loop order, the Collins-Soper-Sterman resummation formalism can be applied to derive the Sudakov form factor. We compare the singular behavior of resummation calculation to fixed order prediction in the case that a Higgs boson and high PT jet are produced nearly back to back in their transverse momenta, and find perfect agreement. The phenomenological importance of the resummation effect at the LHC is also demonstrated.

  13. Detecting deviations from metronomic timing in music: effects of perceptual structure on the mental timekeeper.

    PubMed

    Repp, B H

    1999-04-01

    The detectability of a deviation from metronomic timing--of a small local increment in interonset interval (IOI) duration--in a musical excerpt is subject to positional biases, or "timing expectations," that are closely related to the expressive timing (sequence of IOI durations) typically produced by musicians in performance (Repp, 1992b, 1998c, 1998d). Experiment 1 replicated this finding with some changes in procedure and showed that the perception-performance correlation is not the result of formal musical training or availability of a musical score. Experiments 2 and 3 used a synchronization task to examine the hypothesis that participants' perceptual timing expectations are due to systematic modulations in the period of a mental timekeeper that also controls perceptual-motor coordination. Indeed, there was systematic variation in the asynchronies between taps and metronomically timed musical event onsets, and this variation was correlated both with the variations in IOI increment detectability (Experiment 1) and with the typical expressive timing pattern in performance. When the music contained local IOI increments (Experiment 2), they were almost perfectly compensated for on the next tap, regardless of their detectability in Experiment 1, which suggests a perceptual-motor feedback mechanism that is sensitive to subthreshold timing deviations. Overall, the results suggest that aspects of perceived musical structure influence the predictions of mental timekeeping mechanisms, thereby creating a subliminal warping of experienced time.

  14. Adaptive and maladaptive perfectionism, and professional burnout among medical laboratory scientists.

    PubMed

    Robakowska, Marlena; Tyrańska-Fobke, Anna; Walkiewicz, Maciej; Tartas, Małgorzata

    2018-05-22

    The goal of this paper is to verify the correlations between adaptive and maladaptive perfectionism and the selected demographic and job characteristics vs. professional burnout among medical laboratory scientists in Poland. The study group consisted of 166 laboratory scientists. The Polish Adaptive and Maladaptive Perfectionism Questionnaire (Szczucka) was used for testing perfectionism. The Oldenburg Burnout Inventory was used for examining burnout syndrome. Adaptive perfectionism was positively and maladaptive perfectionism was negatively correlated with both aspects of professional burnout: the disengagement from work and exhaustion. What is more, maladaptive perfectionism was correlated negatively with age and work experience. People in relationships have a higher level of disengagement and a higher level of exhaustion than single ones. The results of hierarchical regression analyses have revealed, after having controlled selected demographic and job factors, that a significant predictor of disengagement is the high level of adaptive perfectionism and low level of maladaptive perfectionism. In addition, a significant predictor of high level of exhaustion is the low level of maladaptive perfectionism. Professional burnout among medical laboratory scientists is of a specific nature. The "healthier" perfectionism they reveal, the higher level of burnout they present. In this profession, lower risk of burnout is represented by those who are characterized by the lack of confidence in the quality of their actions and a negative reaction to their own imperfections associated with imposed social obligation to be perfect. The individuals pursuing their internal high standards experience burnout faster. Med Pr 2018;69(3):253-260. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

  15. Two faces of entropy and information in biological systems.

    PubMed

    Mitrokhin, Yuriy

    2014-10-21

    The article attempts to overcome the well-known paradox of contradictions between the emerging biological organization and entropy production in biological systems. It is assumed that quality, speculative correlation between entropy and antientropy processes taking place both in the past and today in the metabolic and genetic cellular systems may be perfectly authorized for adequate description of the evolution of biological organization. So far as thermodynamic entropy itself cannot compensate for the high degree of organization which exists in the cell, we discuss the mode of conjunction of positive entropy events (mutations) in the genetic systems of the past generations and the formation of organized structures of current cells. We argue that only the information which is generated in the conditions of the information entropy production (mutations and other genome reorganization) in genetic systems of the past generations provides the physical conjunction of entropy and antientropy processes separated from each other in time generations. It is readily apparent from the requirements of the Second law of thermodynamics. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. In vitro comparison of water displacement method and 3 Tesla MRI for MR-volumetry of the olfactory bulb: which sequence is appropriate?

    PubMed

    Burmeister, Hartmut Peter; Möslein, Constanze; Bitter, Thomas; Fröber, Rosemarie; Herrmann, Karl-Heinz; Baltzer, Pascal Andreas Thomas; Gudziol, Hilmar; Dietzel, Matthias; Guntinas-Lichius, Orlando; Kaiser, Werner Alois

    2011-10-01

    Magnetic resonance imaging olfactory bulb (OB) volumetry (OBV) is already used as a complementary prognostic tool to assess olfactory disorders. However, a reference standard in imaging for OBV has not been established. The aim of this in vitro study was to compare volumetric results of different magnetic resonance sequences for OBV at 3 T to genuine OB volumes measured by water displacement. The volumes of 15 human cadaveric OBs were measured using the water displacement method in this institutional review board-approved prospective study. The magnetic resonance imaging protocol at 3 T included constructive interference in steady state (CISS), T2-weighted (T2w) three-dimensional (3D) sampling perfection with application-optimized contrasts using different flip-angle evolutions (SPACE), T2w two-dimensional (2D) turbo spin-echo (TSE), and T1-weighted (T1w) 3D fast low-angle shot (FLASH) sequences. Two blinded observers independently performed two OB volumetric assessments per bulbus and sequence. Intraobserver and interobserver reliabilities were assessed by intraclass correlation coefficients. Bland-Altman plots were analyzed to evaluate systematic biases and concordance correlation coefficients to assess reproducibility. For both observers, intraclass correlation coefficient analysis yielded almost perfect results for intraobserver reliability (CISS, 0.94-0.98; T2w 3D SPACE, 0.93-0.98; T2w 2D TSE, 0.98-0.98; T1w 3D FLASH, 0.95-0.99). Interobserver reliability showed almost perfect agreement for all sequences (CISS, 0.98; T2w 3D SPACE, 0.89; T2w 2D TSE, 0.93; T1w 3D FLASH, 0.97). The CISS sequence yielded the highest mean concordance correlation coefficient (0.95) and the highest combination of precision (0.97) and accuracy (0.98) values. In comparison with the water displacement method, Bland-Altman analyses revealed the lowest systematic bias (-0.5%) for the CISS sequence, followed by T1w 3D FLASH (-1.3%), T2w 3D SPACE (-7.5%), and T2w 2D TSE (-10.9%) sequences. Compared to the water displacement method, the CISS sequence is suited best to validly and reliably measure OB volumes because of its highest values for accuracy and precision and lowest systematic bias. Copyright © 2011 AUR. Published by Elsevier Inc. All rights reserved.

  17. Quantum-state transfer through long-range correlated disordered channels

    NASA Astrophysics Data System (ADS)

    Almeida, Guilherme M. A.; de Moura, Francisco A. B. F.; Lyra, Marcelo L.

    2018-05-01

    We study quantum-state transfer in XX spin-1/2 chains where both communicating spins are weakly coupled to a channel featuring disordered on-site magnetic fields. Fluctuations are modeled by long-range correlated sequences with self-similar profile obeying a power-law spectrum. We show that the channel is able to perform almost perfect quantum-state transmissions even in the presence of significant amounts of disorder provided the degree of those correlations is strong enough, with the cost of having long transfer times and unavoidable timing errors. Still, we show that the lack of mirror symmetry in the channel does not affect much the likelihood of having high-quality outcomes. Our results suggest that coexistence between localized and delocalized states can diminish effects of static perturbations in solid-state devices for quantum communication.

  18. Radar correlated imaging for extended target by the combination of negative exponential restraint and total variation

    NASA Astrophysics Data System (ADS)

    Qian, Tingting; Wang, Lianlian; Lu, Guanghua

    2017-07-01

    Radar correlated imaging (RCI) introduces the optical correlated imaging technology to traditional microwave imaging, which has raised widespread concern recently. Conventional RCI methods neglect the structural information of complex extended target, which makes the quality of recovery result not really perfect, thus a novel combination of negative exponential restraint and total variation (NER-TV) algorithm for extended target imaging is proposed in this paper. The sparsity is measured by a sequential order one negative exponential function, then the 2D total variation technique is introduced to design a novel optimization problem for extended target imaging. And the proven alternating direction method of multipliers is applied to solve the new problem. Experimental results show that the proposed algorithm could realize high resolution imaging efficiently for extended target.

  19. Assessment of Histological Remission in Ulcerative Colitis: Discrepancies Between Daily Practice and Expert Opinion.

    PubMed

    Römkens, Tessa E H; Kranenburg, Pim; Tilburg, Arjan van; Bronkhorst, Carolien; Nagtegaal, Iris D; Drenth, Joost P H; Hoentjen, Frank

    2018-03-28

    Histological remission [HR] is a potential treatment target in ulcerative colitis [UC]. Limited 'real world' data are available on the reliability of histological scoring when assessing minimal histological inflammation. The aim of this study was to investigate the reliability of UC histological scores in colonic biopsies showing mucosal healing [MH] and limited histological inflammation, and to compare the 'daily practice' histological assessment with expert reviews by gastrointestinal [GI] pathologists. We performed a retrospective single-centre study. Colonic biopsies from UC patients with MH [Mayo score ≤ 1] were included. All biopsies assessed in daily practice were reassessed by three blinded GI pathologists using three histological scores (Geboes score [GS], Riley score [RS], Harpaz [Gupta] Index [HGI]) and a global visual scale [GVS]. We evaluated inter- and intra-observer variation between GI pathologists and correlations between scores including the initial histological assessment using Cronbach's alpha and Spearman rho analysis. In total, 270 biopsies from 39 UC patients were included. The inter-observer concordance for all histological indexes was substantial to almost perfect [GS 0.84; HGI 0.61; GVS 0.74, RS 0.91]. Correlation between the RS and GS was almost perfect [R = 0.86], but we found no correlation between the primary histological assessment and reassessment by GI pathologists. Current UC histological scores reliably assess limited histological inflammation in UC patients. The discrepancy between the initial histological assessment and the reassessment by dedicated GI pathologists suggests a gap between daily practice and academic expertise. This issue may limit the implementation of HR as a treatment target for UC in daily practice.

  20. Shear wave elastography for breast masses is highly reproducible.

    PubMed

    Cosgrove, David O; Berg, Wendie A; Doré, Caroline J; Skyba, Danny M; Henry, Jean-Pierre; Gay, Joel; Cohen-Bacrie, Claude

    2012-05-01

    To evaluate intra- and interobserver reproducibility of shear wave elastography (SWE) for breast masses. For intraobserver reproducibility, each observer obtained three consecutive SWE images of 758 masses that were visible on ultrasound. 144 (19%) were malignant. Weighted kappa was used to assess the agreement of qualitative elastographic features; the reliability of quantitative measurements was assessed by intraclass correlation coefficients (ICC). For the interobserver reproducibility, a blinded observer reviewed images and agreement on features was determined. Mean age was 50 years; mean mass size was 13 mm. Qualitatively, SWE images were at least reasonably similar for 666/758 (87.9%). Intraclass correlation for SWE diameter, area and perimeter was almost perfect (ICC ≥ 0.94). Intraobserver reliability for maximum and mean elasticity was almost perfect (ICC = 0.84 and 0.87) and was substantial for the ratio of mass-to-fat elasticity (ICC = 0.77). Interobserver agreement was moderate for SWE homogeneity (κ = 0.57), substantial for qualitative colour assessment of maximum elasticity (κ = 0.66), fair for SWE shape (κ = 0.40), fair for B-mode mass margins (κ = 0.38), and moderate for B-mode mass shape (κ = 0.58), orientation (κ = 0.53) and BI-RADS assessment (κ = 0.59). SWE is highly reproducible for assessing elastographic features of breast masses within and across observers. SWE interpretation is at least as consistent as that of BI-RADS ultrasound B-mode features. • Shear wave ultrasound elastography can measure the stiffness of breast tissue • It provides a qualitatively and quantitatively interpretable colour-coded map of tissue stiffness • Intraobserver reproducibility of SWE is almost perfect while intraobserver reproducibility of SWE proved to be moderate to substantial • The most reproducible SWE features between observers were SWE image homogeneity and maximum elasticity.

  1. Entangled state quantum cryptography: eavesdropping on the ekert protocol

    PubMed

    Naik; Peterson; White; Berglund; Kwiat

    2000-05-15

    Using polarization-entangled photons from spontaneous parametric down-conversion, we have implemented Ekert's quantum cryptography protocol. The near-perfect correlations of the photons allow the sharing of a secret key between two parties. The presence of an eavesdropper is continually checked by measuring Bell's inequalities. We investigated several possible eavesdropper strategies, including pseudo-quantum-nondemolition measurements. In all cases, the eavesdropper's presence was readily apparent. We discuss a procedure to increase her detectability.

  2. The Essential Manual for Asperger Syndrome (ASD) in the Classroom: What Every Teacher Needs to Know

    ERIC Educational Resources Information Center

    Hoopmann, Kathy

    2015-01-01

    Perfect for time-poor teachers, Kathy Hoopmann's essential handbook is an easy-to-navigate resource that promotes a positive learning environment in which students with Asperger syndrome (ASD) can thrive. Kathy's unique ability to explain the ASD mind-set shines through as her concise descriptions reveal how to recognise and develop the child's…

  3. Game and Information Theory Analysis of Electronic Counter Measures in Pursuit-Evasion Games

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Griffin, Christopher H

    Two-player Pursuit-Evasion games in the literature typically either assume both players have perfect knowledge of the opponent s positions or use primitive sensing models. This unrealistically skews the problem in favor of the pursuer who need only maintain a faster velocity at all turning radii. In real life, an evader usually escapes when the pursuer no longer knows the evader s position. In our previous work, we modeled pursuit-evasion without perfect information as a two-player bi-matrix game by using a realistic sensor model and information theory to compute game theoretic payoff matrices. That game has a saddle point when themore » evader uses strategies that exploit sensor limitations, while the pursuer relies on strategies that ignore the sensing limitations. In this paper, we consider for the first time the effect of many types of electronic counter measures (ECM) on pursuit evasion games. The evader s decision to initiate its ECM is modeled as a function of the distance between the players. Simulations show how to find optimal strategies for ECM use when initial conditions are known. We also discuss the effectiveness of different ECM technologies in pursuit-evasion games.« less

  4. Quantum capacity of quantum black holes

    NASA Astrophysics Data System (ADS)

    Adami, Chris; Bradler, Kamil

    2014-03-01

    The fate of quantum entanglement interacting with a black hole has been an enduring mystery, not the least because standard curved space field theory does not address the interaction of black holes with matter. We discuss an effective Hamiltonian of matter interacting with a black hole that has a precise analogue in quantum optics and correctly reproduces both spontaneous and stimulated Hawking radiation with grey-body factors. We calculate the quantum capacity of this channel in the limit of perfect absorption, as well as in the limit of a perfectly reflecting black hole (a white hole). We find that the white hole is an optimal quantum cloner, and is isomorphic to the Unruh channel with positive quantum capacity. The complementary channel (across the horizon) is entanglement-breaking with zero capacity, avoiding a violation of the quantum no-cloning theorem. The black hole channel on the contrary has vanishing capacity, while its complement has positive capacity instead. Thus, quantum states can be reconstructed faithfully behind the black hole horizon, but not outside. This work sheds new light on black hole complementarity because it shows that black holes can both reflect and absorb quantum states without violating the no-cloning theorem, and makes quantum firewalls obsolete.

  5. Characterization Of Improved Binary Phase-Only Filters In A Real-Time Coherent Optical Correlation System

    NASA Astrophysics Data System (ADS)

    Flannery, D.; Keller, P.; Cartwright, S.; Loomis, J.

    1987-06-01

    Attractive correlation system performance potential is possible using magneto-optic spatial light modulators (SLM) to implement binary phase-only reference filters at high rates, provided the correlation performance of such reduced-information-content filters is adequate for the application. In the case studied here, the desired filter impulse response is a rectangular shape, which cannot be achieved with the usual binary phase-only filter formulation. The correlation application problem is described and techniques for synthesizing improved filter impulse response are considered. A compromise solution involves the cascading of a fixed amplitude-only weighting mask with the binary phase-only SLM. Based on simulations presented, this approach provides improved impulse responses and good correlation performance, while retaining the critical feature of real-time variations of the size, shape, and orientation of the rectangle by electronic programming of the phase pattern in the SLM. Simulations indicate that, for at least one very challenging input scene clutter situation, these filters provide higher correlation signal-to-noise than does "ideal" correlation, i.e. using a perfect rectangle filter response.

  6. Just Perfect, Part 2

    ERIC Educational Resources Information Center

    Scott, Paul

    2007-01-01

    In "Just Perfect: Part 1," the author defined a perfect number N to be one for which the sum of the divisors d (1 less than or equal to d less than N) is N. He gave the first few perfect numbers, starting with those known by the early Greeks. In this article, the author provides an extended list of perfect numbers, with some comments about their…

  7. An enhanced methodology for spacecraft correlation activity using virtual testing tools

    NASA Astrophysics Data System (ADS)

    Remedia, Marcello; Aglietti, Guglielmo S.; Appolloni, Matteo; Cozzani, Alessandro; Kiley, Andrew

    2017-11-01

    Test planning and post-test correlation activity have been issues of growing importance in the last few decades and many methodologies have been developed to either quantify or improve the correlation between computational and experimental results. In this article the methodologies established so far are enhanced with the implementation of a recently developed procedure called Virtual Testing. In the context of fixed-base sinusoidal tests (commonly used in the space sector for correlation), there are several factors in the test campaign that affect the behaviour of the satellite and are not normally taken into account when performing analyses: different boundary conditions created by the shaker's own dynamics, non-perfect control system, signal delays etc. All these factors are the core of the Virtual Testing implementation, which will be thoroughly explained in this article and applied to the specific case of Bepi-Colombo spacecraft tested on the ESA QUAD Shaker. Correlation activity will be performed in the various stages of the process, showing important improvements observed after applying the final complete methodology.

  8. Decoherence in yeast cell populations and its implications for genome-wide expression noise.

    PubMed

    Briones, M R S; Bosco, F

    2009-01-20

    Gene expression "noise" is commonly defined as the stochastic variation of gene expression levels in different cells of the same population under identical growth conditions. Here, we tested whether this "noise" is amplified with time, as a consequence of decoherence in global gene expression profiles (genome-wide microarrays) of synchronized cells. The stochastic component of transcription causes fluctuations that tend to be amplified as time progresses, leading to a decay of correlations of expression profiles, in perfect analogy with elementary relaxation processes. Measuring decoherence, defined here as a decay in the auto-correlation function of yeast genome-wide expression profiles, we found a slowdown in the decay of correlations, opposite to what would be expected if, as in mixing systems, correlations decay exponentially as the equilibrium state is reached. Our results indicate that the populational variation in gene expression (noise) is a consequence of temporal decoherence, in which the slow decay of correlations is a signature of strong interdependence of the transcription dynamics of different genes.

  9. Multiscale multifractal detrended cross-correlation analysis of financial time series

    NASA Astrophysics Data System (ADS)

    Shi, Wenbin; Shang, Pengjian; Wang, Jing; Lin, Aijing

    2014-06-01

    In this paper, we introduce a method called multiscale multifractal detrended cross-correlation analysis (MM-DCCA). The method allows us to extend the description of the cross-correlation properties between two time series. MM-DCCA may provide new ways of measuring the nonlinearity of two signals, and it helps to present much richer information than multifractal detrended cross-correlation analysis (MF-DCCA) by sweeping all the range of scale at which the multifractal structures of complex system are discussed. Moreover, to illustrate the advantages of this approach we make use of the MM-DCCA to analyze the cross-correlation properties between financial time series. We show that this new method can be adapted to investigate stock markets under investigation. It can provide a more faithful and more interpretable description of the dynamic mechanism between financial time series than traditional MF-DCCA. We also propose to reduce the scale ranges to analyze short time series, and some inherent properties which remain hidden when a wide range is used may exhibit perfectly in this way.

  10. Transient and Sharvin resistances of Luttinger liquids

    NASA Astrophysics Data System (ADS)

    Kloss, Thomas; Weston, Joseph; Waintal, Xavier

    2018-04-01

    Although the intrinsic conductance of an interacting one-dimensional system is renormalized by the electron-electron correlations, it has been known for some time that this renormalization is washed out by the presence of the (noninteracting) electrodes to which the wire is connected. Here, we study the transient conductance of such a wire: a finite voltage bias is suddenly applied across the wire and we measure the current before it has enough time to reach its stationary value. These calculations allow us to extract the Sharvin (contact) resistance of Luttinger and Fermi liquids. In particular, we find that a perfect junction between a Fermi liquid electrode and a Luttinger liquid electrode is characterized by a contact resistance that consists of half the quantum of conductance in series with half the intrinsic resistance of an infinite Luttinger liquid. These results were obtained using two different methods: a dynamical Hartree-Fock approach and a self-consistent Boltzmann approach. Although these methods are formally approximate, we find a perfect match with the exact results of Luttinger/Fermi liquid theory.

  11. Cadastral data model established and perfected with 4S technology

    NASA Astrophysics Data System (ADS)

    He, Beijing; He, Jiang; He, Jianpeng

    1998-08-01

    Considering China's social essential system and the actual case of the formation of cadastral information in urban and rural area, and based on the 4S technology and the theory and method of canton's GPS geodetic data bench developed by the authors, we thoroughly research on some correlative technical problems about establishing and perfecting all-level's microcosmic cadastral data model (called model in the following) once again. Such problems as the following are included: cadastral, feature and topographic information and its modality and expressing method, classifying and grading the model, coordinate system to be selected, data basis for the model, the collecting method and digitalization of information, database's structural model, mathematical model and the establishing technology of 3 or more dimensional model, dynamic monitoring of and the development and application of the model. Then, the domestic and overseas application prospect is revealed. It also has the tendency to intrude markets cooperated with 'data bench' technology or RS image maps' all-analysis digital surveying and mapping technology.

  12. Laboratory multiple-crystal X-ray topography and reciprocal-space mapping of protein crystals: influence of impurities on crystal perfection

    NASA Technical Reports Server (NTRS)

    Hu, Z. W.; Thomas, B. R.; Chernov, A. A.

    2001-01-01

    Double-axis multiple-crystal X-ray topography, rocking-curve measurements and triple-axis reciprocal-space mapping have been combined to characterize protein crystals using a laboratory source. Crystals of lysozyme and lysozyme crystals doped with acetylated lysozyme impurities were examined. It was shown that the incorporation of acetylated lysozyme into crystals of lysozyme induces mosaic domains that are responsible for the broadening and/or splitting of rocking curves and diffraction-space maps along the direction normal to the reciprocal-lattice vector, while the overall elastic lattice strain of the impurity-doped crystals does not appear to be appreciable in high angular resolution reciprocal-space maps. Multiple-crystal monochromatic X-ray topography, which is highly sensitive to lattice distortions, was used to reveal the spatial distribution of mosaic domains in crystals which correlates with the diffraction features in reciprocal space. Discussions of the influence of acetylated lysozyme on crystal perfection are given in terms of our observations.

  13. Laboratory multiple-crystal X-ray topography and reciprocal-space mapping of protein crystals: influence of impurities on crystal perfection.

    PubMed

    Hu, Z W; Thomas, B R; Chernov, A A

    2001-06-01

    Double-axis multiple-crystal X-ray topography, rocking-curve measurements and triple-axis reciprocal-space mapping have been combined to characterize protein crystals using a laboratory source. Crystals of lysozyme and lysozyme crystals doped with acetylated lysozyme impurities were examined. It was shown that the incorporation of acetylated lysozyme into crystals of lysozyme induces mosaic domains that are responsible for the broadening and/or splitting of rocking curves and diffraction-space maps along the direction normal to the reciprocal-lattice vector, while the overall elastic lattice strain of the impurity-doped crystals does not appear to be appreciable in high angular resolution reciprocal-space maps. Multiple-crystal monochromatic X-ray topography, which is highly sensitive to lattice distortions, was used to reveal the spatial distribution of mosaic domains in crystals which correlates with the diffraction features in reciprocal space. Discussions of the influence of acetylated lysozyme on crystal perfection are given in terms of our observations.

  14. Class of near-perfect coded apertures

    NASA Technical Reports Server (NTRS)

    Cannon, T. M.; Fenimore, E. E.

    1977-01-01

    Coded aperture imaging of gamma ray sources has long promised an improvement in the sensitivity of various detector systems. The promise has remained largely unfulfilled, however, for either one of two reasons. First, the encoding/decoding method produces artifacts, which even in the absence of quantum noise, restrict the quality of the reconstructed image. This is true of most correlation-type methods. Second, if the decoding procedure is of the deconvolution variety, small terms in the transfer function of the aperture can lead to excessive noise in the reconstructed image. It is proposed to circumvent both of these problems by use of a uniformly redundant array (URA) as the coded aperture in conjunction with a special correlation decoding method.

  15. Analytic Study of Induced Pressure on Long Bodies of Revolution with Varying Nose Bluntness at Hypersonic Speeds

    NASA Technical Reports Server (NTRS)

    VanHise, Vernon

    1961-01-01

    Pressure distributions and shock shapes for a series of cylindrical afterbodies having nose fineness ratios from 0.4 to 4 have been calculated by using the method of characteristics for a perfect gas. The fluid mediums investigated were air and helium and the Mach number range was from 5 to 40. Flow parameters obtained from blast-wave analogy gave good correlations of blunt-nose induced pressures and shock shapes. Experimental results are found to be in good agreement with the characteristic calculations. The concept of hypersonic similitude enables good correlation of the results with respect to body shape, Mach number, and ratio of specific heats.

  16. [Technological innovations in radiation oncology require specific quality controls].

    PubMed

    Lenaerts, E; Mathot, M

    2014-01-01

    During the last decade, the field of radiotherapy has benefited from major technological innovations and continuously improving treatment efficacy, comfort and safety of patients. This mainly concerns the imaging techniques that allow 4D CT scan recording the respiratory phases, on-board imaging on linear accelerators that ensure perfect positioning of the patient for treatment and irradiation techniques that reduce very significantly the duration of treatment sessions without compromising quality of the treatment plan, including IMRT (Intensity Modulated Radiation Therapy) and VMAT (Volumetric Modulated Arc therapy). In this context of rapid technological change, it is the responsibility of medical physicists to regularly and precisely monitor the perfect functioning of new techniques to ensure patient safety. This requires the use of specific quality control equipment best suited to these new techniques. We will briefly describe the measurement system Delta4 used to control individualized treatment plan for each patient treated with VMAT technology.

  17. Quasi-crystalline and disordered photonic structures fabricated using direct laser writing

    NASA Astrophysics Data System (ADS)

    Sinelnik, Artem D.; Pinegin, Konstantin V.; Bulashevich, Grigorii A.; Rybin, Mikhail V.; Limonov, Mikhail F.; Samusev, Kirill B.

    2017-09-01

    Direct laser writing is a rapid prototyping technology that has been utilized for the fabrication of micro- and nano-scale materials that have a perfect structure in most of the cases. In this study we exploit the direct laser writing to create several classes of non-periodic materials, such as quasi-crystalline lattices and three-dimensional (3D) objects with an orientation disorder in structural elements. Among quasi-crystalline lattices we consider Penrose tiling and Lévy-type photonic glasses. Images of the fabricated structures are obtained with a scanning electron microscope. In experiment we study the optical diffraction from 3D woodpile photonic structures with orientation disorder and analyze diffraction patters observed on a flat screen positioned behind the sample. With increasing of the disorder degree, we find an impressive transformation of the diffraction patterns from perfect Laue picture to a speckle pattern.

  18. Study of a Car Body Tilting System Using a Variable Link Mechanism: Fundamental Characteristics of Pendulum Motion and Strategy for Perfect Tilting

    NASA Astrophysics Data System (ADS)

    Yoshida, Hidehisa; Nagai, Masao

    This paper analyzes the fundamental dynamic characteristics of a tilting railway vehicle using a variable link mechanism for compensating both the lateral acceleration experienced by passengers and the wheel load imbalance between the inner and outer rails. The geometric relations between the center of rotation, the center of gravity, and the positions of all four links of the tilting system are analyzed. Then, equations of the pendulum motions of the railway vehicle body with a four-link mechanism are derived. A theoretically discussion is given on the geometrical shapes employed in the link mechanism that can simultaneously provide zero lateral acceleration and zero wheel load fluctuation. Then, the perfect tilting condition, which is the control target of the feedforward tilting control, is derived from the linear equation of tilting motion.

  19. Analysis of the vibratory excitation arising from spiral bevel gears

    NASA Technical Reports Server (NTRS)

    Mark, William D.

    1987-01-01

    Tools required to understand and predict in terms of its underlying causes the vibratory excitation arising from meshing spiral bevel gears are developed. A generalized three component transmission error of meshing spiral bevel gears is defined. Equations are derived that yield the three components of the generalized transmission error in terms of deviations of tooth running surfaces from equispaced perfect spherical involute surfaces and tooth/gearbody elastic deformations arising from the three components of the generalized force transmitted by the meshing gears. A method for incorporating these equations into the equations of motion of a gear system is described. Equations are derived for the three components of the generalized force transmitted by the gears which are valid whenever inertial effects of the meshing gears and their supports are negligible. Bearing offsets from the positions occupied by the shaft centerlines of perfect spherical involute bevel gears and bearing/bearing support flexibilities enter into the computation of these forces.

  20. Experimental bit commitment based on quantum communication and special relativity.

    PubMed

    Lunghi, T; Kaniewski, J; Bussières, F; Houlmann, R; Tomamichel, M; Kent, A; Gisin, N; Wehner, S; Zbinden, H

    2013-11-01

    Bit commitment is a fundamental cryptographic primitive in which Bob wishes to commit a secret bit to Alice. Perfectly secure bit commitment between two mistrustful parties is impossible through asynchronous exchange of quantum information. Perfect security is however possible when Alice and Bob split into several agents exchanging classical and quantum information at times and locations suitably chosen to satisfy specific relativistic constraints. Here we report on an implementation of a bit commitment protocol using quantum communication and special relativity. Our protocol is based on [A. Kent, Phys. Rev. Lett. 109, 130501 (2012)] and has the advantage that it is practically feasible with arbitrary large separations between the agents in order to maximize the commitment time. By positioning agents in Geneva and Singapore, we obtain a commitment time of 15 ms. A security analysis considering experimental imperfections and finite statistics is presented.

  1. Perfect Surface Wave Cloaks

    NASA Astrophysics Data System (ADS)

    Mitchell-Thomas, R. C.; McManus, T. M.; Quevedo-Teruel, O.; Horsley, S. A. R.; Hao, Y.

    2013-11-01

    This Letter presents a method for making an uneven surface behave as a flat surface. This allows an object to be concealed (cloaked) under an uneven portion of the surface, without disturbing the wave propagation on the surface. The cloaks proposed in this Letter achieve perfect cloaking that only relies upon isotropic radially dependent refractive index profiles, contrary to those previously published. In addition, these cloaks are very thin, just a fraction of a wavelength in thickness, yet can conceal electrically large objects. While this paper focuses on cloaking electromagnetic surface waves, the theory is also valid for other types of surface waves. The performance of these cloaks is simulated using dielectric filled waveguide geometries, and the curvature of the surface is shown to be rendered invisible, hiding any object positioned underneath. Finally, a transformation of the required dielectric slab permittivity was performed for surface wave propagation, demonstrating the practical applicability of this technique.

  2. An estimator for the standard deviation of a natural frequency. I.

    NASA Technical Reports Server (NTRS)

    Schiff, A. J.; Bogdanoff, J. L.

    1971-01-01

    A brief review of mean-square approximate systems is given. The case in which the masses are deterministic is considered first in the derivation of an estimator for the upper bound of the standard deviation of a natural frequency. Two examples presented include a two-degree-of-freedom system and a case in which the disorder in the springs is perfectly correlated. For purposes of comparison, a Monte Carlo simulation was done on a digital computer.

  3. An accurate registration technique for distorted images

    NASA Technical Reports Server (NTRS)

    Delapena, Michele; Shaw, Richard A.; Linde, Peter; Dravins, Dainis

    1990-01-01

    Accurate registration of International Ultraviolet Explorer (IUE) images is crucial because the variability of the geometrical distortions that are introduced by the SEC-Vidicon cameras ensures that raw science images are never perfectly aligned with the Intensity Transfer Functions (ITFs) (i.e., graded floodlamp exposures that are used to linearize and normalize the camera response). A technique for precisely registering IUE images which uses a cross correlation of the fixed pattern that exists in all raw IUE images is described.

  4. Metamaterial Perfect Absorber Analyzed by a Meta-Cavity Model Consisting of Multilayer Metasurfaces (Postprint)

    DTIC Science & Technology

    2017-09-05

    metamaterial perfect absorber behaves as a meta-cavity bounded between a resonant metasurface and a metallic thin- film reflector. The perfect absorption...cavity quantum electrodynamics devices. 15. SUBJECT TERMS Metamaterial; meta-cavity; metallic thin- film reflector; Fabry-Perot cavity resonance...metamaterial perfect absorber behaves as a meta-cavity bounded between a resonant metasurface and a metallic thin- film reflector. The perfect absorption is

  5. Casimir effect for perfect electromagnetic conductors (PEMCs): a sum rule for attractive/repulsive forces

    NASA Astrophysics Data System (ADS)

    Rode, Stefan; Bennett, Robert; Yoshi Buhmann, Stefan

    2018-04-01

    We discuss the Casimir effect for boundary conditions involving perfect electromagnetic conductors, which interpolate between perfect electric conductors and perfect magnetic conductors. Based on the corresponding reciprocal Green’s tensor we construct the Green’s tensor for two perfectly reflecting plates with magnetoelectric coupling (non-reciprocal media) within the framework of macroscopic quantum electrodynamics. We calculate the Casimir force between two arbitrary perfect electromagnetic conductor plates, resulting in a universal analytic expression that connects the attractive Casimir force with the repulsive Boyer force. We relate the results to a duality symmetry of electromagnetism.

  6. Magnesium Vacancy Segregation and Fast Pipe Diffusion for the ½<110>{110} Edge Dislocation in MgO

    NASA Astrophysics Data System (ADS)

    Walker, A. M.; Zhang, F.; Wright, K.; Gale, J. D.

    2009-12-01

    The movement of point defects in minerals plays a key role in determining their rheological properties, both by permitting diffusional creep and by allowing recovery by dislocation climb. Point defect diffusion can also control the kinetics of phase transitions and grain growth, and can determine the rate of chemical equilibration between phases. Because of this, and the difficulties associated with experimental studies of diffusion, the simulation of point defect formation and migration has been a subject of considerable interest in computational mineral physics. So far, studies have concentrated on point defects moving through otherwise perfect crystals. In this work we examine the behavior of magnesium vacancies close to the core of an edge dislocation in MgO and find that the dislocation dramatically changes the behavior of the point defect. An atomic scale model of the ½<110>{110} edge dislocation in MgO was constructed by applying the anisotropic linear elastic displacement field to the crystal structure and subsequently minimizing the energy of the crystal close to the dislocation core using a parameterized potential model. This process yielded the structure of an isolated edge dislocation in an otherwise perfect crystal. The energy cost associated with introducing magnesium vacancies around the dislocation was then mapped and compared to the formation energy of an isolated magnesium vacancy in bulk MgO. We find that the formation energy of magnesium vacancies around the dislocation mirrors the elastic strain field. Above the dislocation line σxx and σyy are negative and the strain field is compressional. Atoms are squeezed together to make room for the extra half plane effectively increasing the pressure in this region. Below the dislocation line σxx and σyy are positive and the strain field is dilatational. Planes of atoms are pulled apart to avoid a discontinuity across the glide plane and the effective pressure is decreased. In the region with a compressional strain field the vacancies become less stable than those in perfect MgO. In contrast, the region with a dilatational strain field hosts vacancies which are stabilized compared to the perfect crystal. This is in agreement with the previously observed tendency for increasing pressure to decrease the stability of vacancies in MgO. The most stable position for a magnesium vacancy was found to be 1.7 eV more stable than the vacancy in the bulk crystal, suggesting that vacancies will strongly partition to dislocations in MgO. Finally, the energy profile traced out by a vacancy moving through the bulk crystal was compared with that experienced by a vacancy moving along the dislocation core. A low energy pathway for vacancy migration along the dislocation line was found with a migration energy of 1.6 eV compared with a migration energy in the perfect crystal of 1.9 eV. This shows that vacancies segregated to the dislocation line will be significantly more mobile than vacancies in the perfect crystal. Dislocations will act as pipes, allowing material to be rapidly transported through crystals of MgO.

  7. Practice makes perfect in memory recall

    PubMed Central

    Romani, Sandro; Katkov, Mikhail

    2016-01-01

    A large variability in performance is observed when participants recall briefly presented lists of words. The sources of such variability are not known. Our analysis of a large data set of free recall revealed a small fraction of participants that reached an extremely high performance, including many trials with the recall of complete lists. Moreover, some of them developed a number of consistent input-position-dependent recall strategies, in particular recalling words consecutively (“chaining”) or in groups of consecutively presented words (“chunking”). The time course of acquisition and particular choice of positional grouping were variable among participants. Our results show that acquiring positional strategies plays a crucial role in improvement of recall performance. PMID:26980785

  8. Kerr–anti-de Sitter/de Sitter black hole in perfect fluid dark matter background

    NASA Astrophysics Data System (ADS)

    Xu, Zhaoyi; Hou, Xian; Wang, Jiancheng

    2018-06-01

    We obtain the Kerr–anti-de-sitter (Kerr–AdS) and Kerr–de-sitter (Kerr–dS) black hole (BH) solutions to the Einstein field equation in the perfect fluid dark matter background using the Newman–Janis method and Mathematica package. We discuss in detail the black hole properties and obtain the following main results: (i) From the horizon equation g rr   =  0, we derive the relation between the perfect fluid dark matter parameter α and the cosmological constant Λ when the cosmological horizon exists. For , we find that α is in the range for and for . For positive cosmological constant Λ (Kerr–AdS BH), decreases if , and increases if . For negative cosmological constant (Kerr–dS BH), increases if and decreases if ; (ii) An ergosphere exists between the event horizon and the outer static limit surface. The size of the ergosphere evolves oppositely for and , while decreasing with the increasing . When there is sufficient dark matter around the black hole, the black hole spacetime changes remarkably; (iii) The singularity of these black holes is the same as that of rotational black holes. In addition, we study the geodesic motion using the Hamilton–Jacobi formalism and find that when α is in the above ranges for , stable orbits exist. Furthermore, the rotational velocity of the black hole in the equatorial plane has different behaviour for different α and the black hole spin a. It is asymptotically flat and independent of α if while is asymptotically flat only when α is close to zero if . We anticipate that Kerr–Ads/dS black holes could exist in the universe and our future work will focus on the observational effects of the perfect fluid dark matter on these black holes.

  9. Genotyping by alkaline dehybridization using graphically encoded particles.

    PubMed

    Zhang, Huaibin; DeConinck, Adam J; Slimmer, Scott C; Doyle, Patrick S; Lewis, Jennifer A; Nuzzo, Ralph G

    2011-03-01

    This work describes a nonenzymatic, isothermal genotyping method based on the kinetic differences exhibited in the dehybridization of perfectly matched (PM) and single-base mismatched (MM) DNA duplexes in an alkaline solution. Multifunctional encoded hydrogel particles incorporating allele-specific oligonucleotide (ASO) probes in two distinct regions were fabricated by using microfluidic-based stop-flow lithography. Each particle contained two distinct ASO probe sequences differing at a single base position, and thus each particle was capable of simultaneously probing two distinct target alleles. Fluorescently labeled target alleles were annealed to both probe regions of a particle, and the rate of duplex dehybridization was monitored by using fluorescence microscopy. Duplex dehybridization was achieved through an alkaline stimulus using either a pH step function or a temporal pH gradient. When a single target probe sequence was used, the rate of mismatch duplex dehybridization could be discriminated from the rate of perfect match duplex dehybridization. In a more demanding application in which two distinct probe sequences were used, we found that the rate profiles provided a means to discriminate probe dehybridizations from both of the two mismatched duplexes as well as to distinguish at high certainty the dehybridization of the two perfectly matched duplexes. These results demonstrate an ability of alkaline dehybridization to correctly discriminate the rank hierarchy of thermodynamic stability among four sets of perfect match and single-base mismatch duplexes. We further demonstrate that these rate profiles are strongly temperature dependent and illustrate how the sensitivity can be compensated beneficially by the use of an actuating gradient pH field. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. The Future of Your Only Child: How to Guide Your Child to a Happy and Successful Life

    ERIC Educational Resources Information Center

    Pickhardt, Carl E.

    2008-01-01

    One-child households have doubled over the last two decades making it one of the fastest growing family units in America. The author aids families in understanding the common traits of many adult "onlies"--like shyness, perfection, and intolerance--so that they can better prepare for potential outcomes. He also celebrates the positive qualities of…

  11. Time-localized wavelet multiple regression and correlation

    NASA Astrophysics Data System (ADS)

    Fernández-Macho, Javier

    2018-02-01

    This paper extends wavelet methodology to handle comovement dynamics of multivariate time series via moving weighted regression on wavelet coefficients. The concept of wavelet local multiple correlation is used to produce one single set of multiscale correlations along time, in contrast with the large number of wavelet correlation maps that need to be compared when using standard pairwise wavelet correlations with rolling windows. Also, the spectral properties of weight functions are investigated and it is argued that some common time windows, such as the usual rectangular rolling window, are not satisfactory on these grounds. The method is illustrated with a multiscale analysis of the comovements of Eurozone stock markets during this century. It is shown how the evolution of the correlation structure in these markets has been far from homogeneous both along time and across timescales featuring an acute divide across timescales at about the quarterly scale. At longer scales, evidence from the long-term correlation structure can be interpreted as stable perfect integration among Euro stock markets. On the other hand, at intramonth and intraweek scales, the short-term correlation structure has been clearly evolving along time, experiencing a sharp increase during financial crises which may be interpreted as evidence of financial 'contagion'.

  12. 76 FR 49751 - Perfect Fitness, Provisional Acceptance of a Settlement Agreement and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ... CONSUMER PRODUCT SAFETY COMMISSION [CPSC Docket No. 11-C0009] Perfect Fitness, Provisional...(e). Published below is a provisionally-accepted Settlement Agreement with Perfect Fitness... accordance with 16 CFR 1118.20, Perfect Fitness and staff (``Staff'') of the United States Consumer Product...

  13. 3D Ultrashort TE MRI for Evaluation of Cartilaginous Endplate of Cervical Disk In Vivo: Feasibility and Correlation With Disk Degeneration in T2-Weighted Spin-Echo Sequence.

    PubMed

    Kim, Yeo Ju; Cha, Jang Gyu; Shin, Yoon Sang; Chaudhari, Akshay S; Suh, Young Ju; Hwan Yoon, Seung; Gold, Garry E

    2018-05-01

    The purpose of this study was to evaluate the feasibility of 3D ultrashort TE (UTE) MRI in depicting the cartilaginous endplate (CEP) and its abnormalities and to investigate the association between CEP abnormalities and disk degeneration on T2-weighted spin-echo (SE) MR images in cervical disks in vivo. Eight healthy volunteers and 70 patients were examined using 3-T MRI with the 3D UTE cones trajectory technique (TR/TE, 16.1/0.032, 6.6). In the volunteer study, quantitative and qualitative assessments of CEP depiction were conducted for the 3D UTE and T2-weighted SE imaging. In the patient study, CEP abnormalities were analyzed. Intersequence agreement between the images obtained with the first-echo 3D UTE sequence and the images created by subtracting the second-echo from the first-echo 3D UTE sequence (subtracted 3D UTE) and the intraobserver and interobserver agreements for 3D UTE overall were also tested. The CEP abnormalities on the 3D UTE images correlated with the Miyazaki grading of the T2-weighted SE images. In the volunteer study, the CEP was well visualized on 3D UTE images but not on T2-weighted SE images (p < 0.001). In the patient study, for evaluation of CEP abnormalities, intersequence agreements were substantial to almost perfect, intraobserver agreements were substantial to almost perfect, and interobserver agreements were moderate to substantial (p < 0.001). All of the CEP abnormalities correlated with the Miyazaki grade with statistical significance (p < 0.001). Three-dimensional UTE MRI feasibly depicts the CEP and CEP abnormalities, which may be associated with the severity of disk degeneration on T2-weighted SE MRI.

  14. Validation of spatial variability in downscaling results from the VALUE perfect predictor experiment

    NASA Astrophysics Data System (ADS)

    Widmann, Martin; Bedia, Joaquin; Gutiérrez, Jose Manuel; Maraun, Douglas; Huth, Radan; Fischer, Andreas; Keller, Denise; Hertig, Elke; Vrac, Mathieu; Wibig, Joanna; Pagé, Christian; Cardoso, Rita M.; Soares, Pedro MM; Bosshard, Thomas; Casado, Maria Jesus; Ramos, Petra

    2016-04-01

    VALUE is an open European network to validate and compare downscaling methods for climate change research. Within VALUE a systematic validation framework to enable the assessment and comparison of both dynamical and statistical downscaling methods has been developed. In the first validation experiment the downscaling methods are validated in a setup with perfect predictors taken from the ERA-interim reanalysis for the period 1997 - 2008. This allows to investigate the isolated skill of downscaling methods without further error contributions from the large-scale predictors. One aspect of the validation is the representation of spatial variability. As part of the VALUE validation we have compared various properties of the spatial variability of downscaled daily temperature and precipitation with the corresponding properties in observations. We have used two test validation datasets, one European-wide set of 86 stations, and one higher-density network of 50 stations in Germany. Here we present results based on three approaches, namely the analysis of i.) correlation matrices, ii.) pairwise joint threshold exceedances, and iii.) regions of similar variability. We summarise the information contained in correlation matrices by calculating the dependence of the correlations on distance and deriving decorrelation lengths, as well as by determining the independent degrees of freedom. Probabilities for joint threshold exceedances and (where appropriate) non-exceedances are calculated for various user-relevant thresholds related for instance to extreme precipitation or frost and heat days. The dependence of these probabilities on distance is again characterised by calculating typical length scales that separate dependent from independent exceedances. Regionalisation is based on rotated Principal Component Analysis. The results indicate which downscaling methods are preferable if the dependency of variability at different locations is relevant for the user.

  15. Correlated randomness and switching phenomena

    NASA Astrophysics Data System (ADS)

    Stanley, H. E.; Buldyrev, S. V.; Franzese, G.; Havlin, S.; Mallamace, F.; Kumar, P.; Plerou, V.; Preis, T.

    2010-08-01

    One challenge of biology, medicine, and economics is that the systems treated by these serious scientific disciplines have no perfect metronome in time and no perfect spatial architecture-crystalline or otherwise. Nonetheless, as if by magic, out of nothing but randomness one finds remarkably fine-tuned processes in time and remarkably fine-tuned structures in space. Further, many of these processes and structures have the remarkable feature of “switching” from one behavior to another as if by magic. The past century has, philosophically, been concerned with placing aside the human tendency to see the universe as a fine-tuned machine. Here we will address the challenge of uncovering how, through randomness (albeit, as we shall see, strongly correlated randomness), one can arrive at some of the many spatial and temporal patterns in biology, medicine, and economics and even begin to characterize the switching phenomena that enables a system to pass from one state to another. Inspired by principles developed by A. Nihat Berker and scores of other statistical physicists in recent years, we discuss some applications of correlated randomness to understand switching phenomena in various fields. Specifically, we present evidence from experiments and from computer simulations supporting the hypothesis that water’s anomalies are related to a switching point (which is not unlike the “tipping point” immortalized by Malcolm Gladwell), and that the bubbles in economic phenomena that occur on all scales are not “outliers” (another Gladwell immortalization). Though more speculative, we support the idea of disease as arising from some kind of yet-to-be-understood complex switching phenomenon, by discussing data on selected examples, including heart disease and Alzheimer disease.

  16. The Negative Correlation between Fiber Color and Quality Traits Revealed by QTL Analysis.

    PubMed

    Feng, Hongjie; Guo, Lixue; Wang, Gaskin; Sun, Junling; Pan, Zhaoe; He, Shoupu; Zhu, Heqin; Sun, Jie; Du, Xiongming

    2015-01-01

    Naturally existing colored cotton was far from perfection due to having genetic factors for lower yield, poor fiber quality and monotonous color. These factors posed a challenge to colored cotton breeding and innovation. To identify novel quantitative trait loci (QTL) for fiber color along with understanding of correlation between fiber color and quality in colored cotton, a RIL and two F2 populations were generated from crosses among Zong128 (Brown fiber cotton) and two white fiber cotton lines which were then analyzed in four environments. Two stable and major QTLs (qLC-7-1, qFC-7-1) for fiber lint and fuzz color were detected accounting for 16.01%-59.85% of the phenotypic variation across multiple generations and environments. Meanwhile, some minor QTLs were also identified on chromosomes 5, 14, 21 and 24 providing low phenotypic variation (<5%) from only F2 populations, not from the RILs population. Especially, a multiple-effect locus for fiber color and quality has been detected between flanking markers NAU1043 and NAU3654 on chromosome 7 (A genome) over multiple environments. Of which, qLC-7-1, qFC-7-1 were responsible for positive effects and improved fiber color in offsprings. Meanwhile, the QTLs (qFL-7-1, qFU-7-1, qFF-7-1, qFE-7-1, and qFS-7-1) for fiber quality had negative effects and explained 2.19%-8.78% of the phenotypic variation. This multiple-effect locus for fiber color and quality may reveal the negative correlation between the two types of above traits, so paving the way towards cotton genetic improvement.

  17. Construct Validity of Accelerometry-Derived Force to Quantify Basketball Movement Patterns.

    PubMed

    Staunton, Craig; Wundersitz, Daniel; Gordon, Brett; Kingsley, Michael

    2017-12-01

    This study assessed the construct validity of accelerometry-derived net force to quantify the external demands of basketball movements. Twenty-eight basketballers completed the Yo-Yo intermittent recovery test (Yo-Yo-IR1) and basketball exercise simulation test (BEST). Intensity was quantified using accelerometry-derived average net force (AvF Net ) and PlayerLoad TM per minute (PL/min). Within-player correlations were determined between intensity and running speed during Yo-Yo-IR1. Measured AvF Net was determined for movements during the BEST and predicted AvF Net was calculated using movement speed and correlations from Yo-Yo-IR1. Relationships between AvF Net and running speed during Yo-Yo-IR1 were nearly perfect (r 2 =0.95, 95% CI: 0.94-0.96; p<0.001) and stronger than correlations between running speed and PL/min (r 2 =0.80, 95% CI: 0.73-0.87; p<0.001). Differences between measured and predicted AvF Net were small during jogging and running (<1%), but large for basketball movements including jumping, change-of-direction and shuffling (15%-41%). As hypothesised, AvF Net differed by playing position (11%-16%; p <0.001) and reflected the additional demand upon players with larger body mass and lower movement efficiency. Both sprint speed and AvF Net reduced during the course of the BEST ( p ≤0.013). These findings confirm the construct validity of AvF Net to quantify the external demand of basketball movements. Accelerometry-derived net force has the potential to quantify the external demands of basketballers during training and competition. © Georg Thieme Verlag KG Stuttgart · New York.

  18. Modulating the spin transport behaviors in ZBNCNRs by edge hydrogenation and position of BN chain

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ouyang, Jun; Long, Mengqiu, E-mail: mqlong@csu.edu.cn, E-mail: ygao@csu.edu.cn; Zhang, Dan

    2016-03-15

    Using the density functional theory and the nonequilibrium Green’s function method, we study the spin transport behaviors in zigzag boron-nitrogen-carbon nanoribbons (ZBNCNRs) by modulating the edge hydrogenation and the position of B-N nanoribbons (BNNRs) chain. The different edge hydrogenations of the ZBNCNRs and the different position relationships of the BNNRs have been considered systematically. Our results show that the metallic, semimetallic and semiconductive properties of the ZBNCNRs can be modulated by the different edge hydrogenations and different position relationships of BN chains. And our proposaled ZBNCNRs devices act as perfect spin-filters with nearly 100% spin polarization. These effects would havemore » potential applications for boron-nitrogen-carbon-based nanomaterials in spintronics nano-devices.« less

  19. Detailed Abundances of Planet-hosting Wide Binaries. I. Did Planet Formation Imprint Chemical Signatures in the Atmospheres of HD 20782/81?

    NASA Astrophysics Data System (ADS)

    Mack, Claude E., III; Schuler, Simon C.; Stassun, Keivan G.; Norris, John

    2014-06-01

    Using high-resolution, high signal-to-noise echelle spectra obtained with Magellan/MIKE, we present a detailed chemical abundance analysis of both stars in the planet-hosting wide binary system HD 20782 + HD 20781. Both stars are G dwarfs, and presumably coeval, forming in the same molecular cloud. Therefore we expect that they should possess the same bulk metallicities. Furthermore, both stars also host giant planets on eccentric orbits with pericenters lsim0.2 AU. Here, we investigate if planets with such orbits could lead to the host stars ingesting material, which in turn may leave similar chemical imprints in their atmospheric abundances. We derived abundances of 15 elements spanning a range of condensation temperature, T C ≈ 40-1660 K. The two stars are found to have a mean element-to-element abundance difference of 0.04 ± 0.07 dex, which is consistent with both stars having identical bulk metallicities. In addition, for both stars, the refractory elements (T C >900 K) exhibit a positive correlation between abundance (relative to solar) and T C, with similar slopes of ≈1×10-4 dex K-1. The measured positive correlations are not perfect; both stars exhibit a scatter of ≈5×10-5 dex K-1 about the mean trend, and certain elements (Na, Al, Sc) are similarly deviant in both stars. These findings are discussed in the context of models for giant planet migration that predict the accretion of H-depleted rocky material by the host star. We show that a simple simulation of a solar-type star accreting material with Earth-like composition predicts a positive—but imperfect—correlation between refractory elemental abundances and T C. Our measured slopes are consistent with what is predicted for the ingestion of 10-20 Earths by each star in the system. In addition, the specific element-by-element scatter might be used to distinguish between planetary accretion and Galactic chemical evolution scenarios. The data presented herein were obtained at the Las Campanas Observatory with the Magellan/MIKE spectrograph.

  20. Entangled State Quantum Cryptography: Eavesdropping on the Ekert Protocol

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Naik, D. S.; Peterson, C. G.; White, A. G.

    2000-05-15

    Using polarization-entangled photons from spontaneous parametric down-conversion, we have implemented Ekert's quantum cryptography protocol. The near-perfect correlations of the photons allow the sharing of a secret key between two parties. The presence of an eavesdropper is continually checked by measuring Bell's inequalities. We investigated several possible eavesdropper strategies, including pseudo-quantum-nondemolition measurements. In all cases, the eavesdropper's presence was readily apparent. We discuss a procedure to increase her detectability. (c) 2000 The American Physical Society.

  1. Thermal conductance and basal metabolic rate are part of a coordinated system for heat transfer regulation

    PubMed Central

    Naya, Daniel E.; Spangenberg, Lucía; Naya, Hugo; Bozinovic, Francisco

    2013-01-01

    Thermal conductance measures the ease with which heat leaves or enters  an organism's body. Although the analysis of this physiological variable in relation to climatic and ecological factors can be traced to studies by Scholander and colleagues, only small advances have occurred ever since. Here, we analyse the relationship between minimal thermal conductance estimated during summer (Cmin) and several ecological, climatic and geographical factors for 127 rodent species, in order to identify the exogenous factors that have potentially affected the evolution of thermal conductance. In addition, we evaluate whether there is compensation between Cmin and basal metabolic rate (BMR)—in such a way that a scale-invariant ratio between both variables is equal to one—as could be expected from the Scholander–Irving model of heat transfer. Our major findings are (i) annual mean temperature is the best single predictor of mass-independent Cmin. (ii) After controlling for the effect of body mass, there is a strong positive correlation between log10 (Cmin) and log10 (BMR). Further, the slope of this correlation is close to one, indicating an almost perfect compensation between both physiological variables. (iii) Structural equation modelling indicated that Cmin values are adjusted to BMR values and not the other way around. Thus, our results strongly suggest that BMR and thermal conductance integrate a coordinated system for heat regulation in endothermic animals and that summer conductance values are adjusted (in an evolutionary sense) to track changes in BMRs. PMID:23902915

  2. Anion-Cation Permeability Correlates with Hydrated Counterion Size in Glycine Receptor Channels

    PubMed Central

    Sugiharto, Silas; Lewis, Trevor M.; Moorhouse, Andrew J.; Schofield, Peter R.; Barry, Peter H.

    2008-01-01

    The functional role of ligand-gated ion channels depends critically on whether they are predominantly permeable to cations or anions. However, these, and other ion channels, are not perfectly selective, allowing some counterions to also permeate. To address the mechanisms by which such counterion permeation occurs, we measured the anion-cation permeabilities of different alkali cations, Li+ Na+, and Cs+, relative to either Cl− or \\documentclass[10pt]{article} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{pmc} \\usepackage[Euler]{upgreek} \\pagestyle{empty} \\oddsidemargin -1.0in \\begin{document} \\begin{equation*}{\\mathrm{NO}}_{3}^{-}\\end{equation*}\\end{document} anions in both a wild-type glycine receptor channel (GlyR) and a mutant GlyR with a wider pore diameter. We hypothesized and showed that counterion permeation in anionic channels correlated inversely with an equivalent or effective hydrated size of the cation relative to the channel pore radius, with larger counterion permeabilities being observed in the wider pore channel. We also showed that the anion component of conductance was independent of the nature of the cation. We suggest that anions and counterion cations can permeate through the pore as neutral ion pairs, to allow the cations to overcome the large energy barriers resulting from the positively charged selectivity filter in small GlyR channels, with the permeability of such ion pairs being dependent on the effective hydrated diameter of the ion pair relative to the pore diameter. PMID:18708455

  3. Basis for substrate recognition and distinction by matrix metalloproteinases

    PubMed Central

    Ratnikov, Boris I.; Cieplak, Piotr; Gramatikoff, Kosi; Pierce, James; Eroshkin, Alexey; Igarashi, Yoshinobu; Kazanov, Marat; Sun, Qing; Godzik, Adam; Osterman, Andrei; Stec, Boguslaw; Strongin, Alex; Smith, Jeffrey W.

    2014-01-01

    Genomic sequencing and structural genomics produced a vast amount of sequence and structural data, creating an opportunity for structure–function analysis in silico [Radivojac P, et al. (2013) Nat Methods 10(3):221–227]. Unfortunately, only a few large experimental datasets exist to serve as benchmarks for function-related predictions. Furthermore, currently there are no reliable means to predict the extent of functional similarity among proteins. Here, we quantify structure–function relationships among three phylogenetic branches of the matrix metalloproteinase (MMP) family by comparing their cleavage efficiencies toward an extended set of phage peptide substrates that were selected from ∼64 million peptide sequences (i.e., a large unbiased representation of substrate space). The observed second-order rate constants [k(obs)] across the substrate space provide a distance measure of functional similarity among the MMPs. These functional distances directly correlate with MMP phylogenetic distance. There is also a remarkable and near-perfect correlation between the MMP substrate preference and sequence identity of 50–57 discontinuous residues surrounding the catalytic groove. We conclude that these residues represent the specificity-determining positions (SDPs) that allowed for the expansion of MMP proteolytic function during evolution. A transmutation of only a few selected SDPs proximal to the bound substrate peptide, and contributing the most to selectivity among the MMPs, is sufficient to enact a global change in the substrate preference of one MMP to that of another, indicating the potential for the rational and focused redesign of cleavage specificity in MMPs. PMID:25246591

  4. Risk aversion, time preference and health production: theory and empirical evidence from Cambodia.

    PubMed

    Rieger, Matthias

    2015-04-01

    This paper quantifies the relationship between risk aversion and discount rates on the one hand and height and weight on the other. It studies this link in the context of poor households in Cambodia. Evidence is based on an original dataset that contains both experimental measures of risk taking and impatience along with anthropometric measurements of children and adults. The aim of the paper is to (i) explore the importance of risk and time preferences in explaining undernutrition and (ii) compare the evidence stemming from poor households to strikingly similar findings from industrialized countries. It uses an inter-generational approach to explain observed correlations in adults and children that is inspired by the height premium on labor markets. Parents can invest in the health capital of their child to increase future earnings and their consumption when old: better nutrition during infancy translates into better human capital and better wages, and ultimately better financial means to take care of elderly parents. However this investment is subject to considerable uncertainty, since parents neither perfectly foresee economic conditions when the child starts earning nor fully observe the ability to transform nutritional investments into long-term health capital. As a result, risk taking households have taller and heavier children. Conversely, impatience does not affect child health. In the case of adults, only weight and the body mass index (BMI), but not height, are positively and moderately correlated with risk taking and impatience. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Thermal conductance and basal metabolic rate are part of a coordinated system for heat transfer regulation.

    PubMed

    Naya, Daniel E; Spangenberg, Lucía; Naya, Hugo; Bozinovic, Francisco

    2013-09-22

    Thermal conductance measures the ease with which heat leaves or enters an organism's body. Although the analysis of this physiological variable in relation to climatic and ecological factors can be traced to studies by Scholander and colleagues, only small advances have occurred ever since. Here, we analyse the relationship between minimal thermal conductance estimated during summer (Cmin) and several ecological, climatic and geographical factors for 127 rodent species, in order to identify the exogenous factors that have potentially affected the evolution of thermal conductance. In addition, we evaluate whether there is compensation between Cmin and basal metabolic rate (BMR)-in such a way that a scale-invariant ratio between both variables is equal to one-as could be expected from the Scholander-Irving model of heat transfer. Our major findings are (i) annual mean temperature is the best single predictor of mass-independent Cmin. (ii) After controlling for the effect of body mass, there is a strong positive correlation between log10 (Cmin) and log10 (BMR). Further, the slope of this correlation is close to one, indicating an almost perfect compensation between both physiological variables. (iii) Structural equation modelling indicated that Cmin values are adjusted to BMR values and not the other way around. Thus, our results strongly suggest that BMR and thermal conductance integrate a coordinated system for heat regulation in endothermic animals and that summer conductance values are adjusted (in an evolutionary sense) to track changes in BMRs.

  6. Congenital heart disease: interrelation between German diagnosis-related groups system and Aristotle complexity score.

    PubMed

    Sinzobahamvya, Nicodème; Photiadis, Joachim; Arenz, Claudia; Kopp, Thorsten; Hraska, Viktor; Asfour, Boulos

    2010-06-01

    The Disease-Related Groups (DRGs) system postulates that inpatient stays with similar levels of clinical complexity are expected to consume similar amounts of resources. This, applied to surgery of congenital heart disease, suggests that the higher the complexity of procedures as estimated by the Aristotle complexity score, the higher hospital reimbursement should be. This study analyses how much case-mix index (CMI) generated by German DRG 2009 version correlates with Aristotle score. A total of 456 DRG cases of year 2008 were regrouped according to German DRG 2009 and related cost-weight values and overall CMI evaluated. Corresponding Aristotle basic and comprehensive complexity scores (ABC and ACC) and levels were determined. Associated surgical performance (Aristotle score times hospital survival) was estimated. Spearman 'r' correlation coefficients were calculated between Aristotle scores and cost-weights. Goodness of fit 'r(2)' from derived regression was determined. Correlation was estimated to be optimal if Spearman 'r' and derived goodness of fit 'r(2)' approached 1 value. CMI was 8.787 while mean ABC and ACC scores were 7.64 and 9.27, respectively. Hospital survival was 98.5%: therefore, surgical performance attained 7.53 (ABC score) and 9.13 (ACC score). ABC and ACC scores and levels positively correlated with cost-weights. With Spearman 'r' of 1 and goodness of fit 'r(2)' of 0.9790, scores of the six ACC levels correlated at best. The equation was y = 0.5591 + 0.939x, in which y stands for cost-weight (CMI) and x for score of ACC level. ACC score correlates almost perfectly with corresponding cost-weights (CMI) generated by the German DRG 2009. It could therefore be used as the basis for hospital reimbursement to compensate in conformity with procedures' complexity. Extrapolated CMI in this series would be 9.264. Modulation of reimbursement according to surgical performance could be established and thus 'reward' quality in congenital heart surgery. Copyright 2009 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

  7. Laminar and turbulent heating predictions for mars entry vehicles

    NASA Astrophysics Data System (ADS)

    Wang, Xiaoyong; Yan, Chao; Zheng, Weilin; Zhong, Kang; Geng, Yunfei

    2016-11-01

    Laminar and turbulent heating rates play an important role in the design of Mars entry vehicles. Two distinct gas models, thermochemical non-equilibrium (real gas) model and perfect gas model with specified effective specific heat ratio, are utilized to investigate the aerothermodynamics of Mars entry vehicle named Mars Science Laboratory (MSL). Menter shear stress transport (SST) turbulent model with compressible correction is implemented to take account of the turbulent effect. The laminar and turbulent heating rates of the two gas models are compared and analyzed in detail. The laminar heating rates predicted by the two gas models are nearly the same at forebody of the vehicle, while the turbulent heating environments predicted by the real gas model are severer than the perfect gas model. The difference of specific heat ratio between the two gas models not only induces the flow structure's discrepancy but also increases the heating rates at afterbody of the vehicle obviously. Simple correlations for turbulent heating augmentation in terms of laminar momentum thickness Reynolds number, which can be employed as engineering level design and analysis tools, are also developed from numerical results. At the time of peak heat flux on the +3σ heat load trajectory, the maximum value of momentum thickness Reynolds number at the MSL's forebody is about 500, and the maximum value of turbulent augmentation factor (turbulent heating rates divided by laminar heating rates) is 5 for perfect gas model and 8 for real gas model.

  8. Ball bearing vibrations amplitude modeling and test comparisons

    NASA Technical Reports Server (NTRS)

    Hightower, Richard A., III; Bailey, Dave

    1995-01-01

    Bearings generate disturbances that, when combined with structural gains of a momentum wheel, contribute to induced vibration in the wheel. The frequencies generated by a ball bearing are defined by the bearing's geometry and defects. The amplitudes at these frequencies are dependent upon the actual geometry variations from perfection; therefore, a geometrically perfect bearing will produce no amplitudes at the kinematic frequencies that the design generates. Because perfect geometry can only be approached, emitted vibrations do occur. The most significant vibration is at the spin frequency and can be balanced out in the build process. Other frequencies' amplitudes, however, cannot be balanced out. Momentum wheels are usually the single largest source of vibrations in a spacecraft and can contribute to pointing inaccuracies if emitted vibrations ring the structure or are in the high-gain bandwidth of a sensitive pointing control loop. It is therefore important to be able to provide an a priori knowledge of possible amplitudes that are singular in source or are a result of interacting defects that do not reveal themselves in normal frequency prediction equations. This paper will describe the computer model that provides for the incorporation of bearing geometry errors and then develops an estimation of actual amplitudes and frequencies. Test results were correlated with the model. A momentum wheel was producing an unacceptable 74 Hz amplitude. The model was used to simulate geometry errors and proved successful in identifying a cause that was verified when the parts were inspected.

  9. Modal energy analysis for mechanical systems excited by spatially correlated loads

    NASA Astrophysics Data System (ADS)

    Zhang, Peng; Fei, Qingguo; Li, Yanbin; Wu, Shaoqing; Chen, Qiang

    2018-10-01

    MODal ENergy Analysis (MODENA) is an energy-based method, which is proposed to deal with vibroacoustic problems. The performance of MODENA on the energy analysis of a mechanical system under spatially correlated excitation is investigated. A plate/cavity coupling system excited by a pressure field is studied in a numerical example, in which four kinds of pressure fields are involved, which include the purely random pressure field, the perfectly correlated pressure field, the incident diffuse field, and the turbulent boundary layer pressure fluctuation. The total energies of subsystems differ to reference solution only in the case of purely random pressure field and only for the non-excited subsystem (the cavity). A deeper analysis on the scale of modal energy is further conducted via another numerical example, in which two structural modes excited by correlated forces are coupled with one acoustic mode. A dimensionless correlation strength factor is proposed to determine the correlation strength between modal forces. Results show that the error on modal energy increases with the increment of the correlation strength factor. A criterion is proposed to establish a link between the error and the correlation strength factor. According to the criterion, the error is negligible when the correlation strength is weak, in this situation the correlation strength factor is less than a critical value.

  10. Contextual Factors in the Use of the Present Perfect

    ERIC Educational Resources Information Center

    Moy, Raymond H.

    1977-01-01

    In this study the inadequacies of rules governing the present perfect in isolated sentences are discussed and then two contextual factors thought to be connected with current relevance and the use of the present perfect are described. These factors are experimentally shown to influence use of the present perfect significantly. (CHK)

  11. Practice Makes Perfect? The Impact of Coaching and Moral Stories on Children's Lie-Telling

    ERIC Educational Resources Information Center

    Talwar, Victoria; Yachison, Sarah; Leduc, Karissa; Nagar, Pooja Megha

    2018-01-01

    Children (n = 202; 4 to 7 years old) witnessed a confederate break a toy and were asked to keep the transgression a secret. Children were randomly assigned to a Coaching condition (i.e., No Coaching, Light Coaching, or Heavy Coaching) and a Moral Story condition (i.e., Positive or Neutral). Overall, 89.7% of children lied about the broken toy when…

  12. Comparison of the measurements of a novel optical biometry: Nidek AL-Scan with Sirius and a ultrasound biometry.

    PubMed

    Çağlar, Çağatay; Kocamış, Sücattin İlker; Demir, Emre; Durmuş, Mustafa

    2017-06-01

    To investigate the accuracy of the measurements of Nidek AL-Scan by comparing with Sirius (CSO, Florence, Italy), a corneal tomography which also employs the Scheimpflug principle, and a commonly used device, ultrasound biometry (UB) (Aviso A/B, Quantel Medical, MT, USA). Right eyes of 85 healthy volunteers (58 women 27 men) with a mean age of 39.24 ± 14.37 years (range 15-68) were enrolled into this comparative prospective study. Average K 2.4, average K 3.3, CCT (central corneal thickness), WTW (white to white distance), ACD (anterior chamber depth) and AL (axial length) were obtained from the AL-Scan and compared with average SimK, CCT, WTW (horizontal anterior chamber diameter) and ACD obtained from Sirius and also compared with ACD and AL obtained from UB. The statistically significant difference was found between all of the measurements (p < 0.001) except the average keratometry values (K2.4, K3.3, SimK) (p = 0.083). There was a perfect correlation between keratometry, CCT and AL measurements of the devices (ICC = 0.977, 0.954, 0.923, respectively) and there was a strong correlation between the WTW measurements of AL-Scan and Sirius (ICC = 0.865). While ACD parameter of AL-Scan and UB showed a perfect correlation (ICC = 0.977), there was a moderate correlation between AL-Scan and Sirius and also between UB and Sirius (ICC = 0.608 and 0.664, respectively). There was a high correlation between the all measurements, besides ACD, of AL-Scan and Sirius and they can be used interchangeably for average keratometry and WTW confidently. However, ACD and CCT have a broader 95 % LoA (-0.039 to 0.744 and -24.985 to 3.691, respectively). In addition, AL-Scan and UB were in good agreement regarding ACD, while differences in AL measurements of UB and AL-Scan were clinically important (95 % LoA = -0.091 to 0.703). Furthermore, UB and Sirius have a moderate agreement regarding ACD (95 % LoA = -0.047 to 0.680).

  13. Solar granulation and statistical crystallography: A modeling approach using size-shape relations

    NASA Technical Reports Server (NTRS)

    Noever, D. A.

    1994-01-01

    The irregular polygonal pattern of solar granulation is analyzed for size-shape relations using statistical crystallography. In contrast to previous work which has assumed perfectly hexagonal patterns for granulation, more realistic accounting of cell (granule) shapes reveals a broader basis for quantitative analysis. Several features emerge as noteworthy: (1) a linear correlation between number of cell-sides and neighboring shapes (called Aboav-Weaire's law); (2) a linear correlation between both average cell area and perimeter and the number of cell-sides (called Lewis's law and a perimeter law, respectively) and (3) a linear correlation between cell area and squared perimeter (called convolution index). This statistical picture of granulation is consistent with a finding of no correlation in cell shapes beyond nearest neighbors. A comparative calculation between existing model predictions taken from luminosity data and the present analysis shows substantial agreements for cell-size distributions. A model for understanding grain lifetimes is proposed which links convective times to cell shape using crystallographic results.

  14. Validation of an indirect ELISA to detect antibodies against BoHV-1 in bovine and guinea-pig serum samples using ISO/IEC 17025 standards.

    PubMed

    Parreño, Viviana; Romera, S Alejandra; Makek, Lucia; Rodriguez, Daniela; Malacari, Darío; Maidana, Silvina; Compaired, Diego; Combessies, Gustavo; Vena, María Marta; Garaicoechea, Lorena; Wigdorovitz, Andrés; Marangunich, Laura; Fernandez, Fernando

    2010-10-01

    Two ELISAs to quantify antibodies to BoHV-1 in the sera of cattle and immunized guinea pigs were developed and validated using ISO/IEC 17025 standards. The cut-off value of the assay was established at 20% positivity of a high positive control for screening of cattle. Using this threshold, the assay properly classified the OIE bovine reference sera EU1, EU2 and EU3. For vaccine potency testing, a cut-off of 40% was selected for both species. The reliability of the assays, given by their diagnostic sensitivity and specificity, using the threshold of 40% was 89.7% and 100%, respectively, for bovines and 94.9% and 100% for guinea pigs, respectively. There was almost perfect agreement between the ELISA and virus neutralization results. In addition, after vaccination, there was a good correlation between the neutralizing and ELISA antibody titers of the serum from the same bovine or guinea pig, sampled at 60 and 30 days post-vaccination, respectively (R(bovine)=0.88, R(guinea pig)=0.92; p<0.0001). A similar correlation was observed when analyzing the mean antibody titers of groups of vaccinated animals (R(bovine)=0.95 and R(guinea pig)=0.97; p<0.0001), indicating the relevance of the ELISAs for batch to batch vaccine potency testing in the target species and in the laboratory animal model. The intermediate precision of the assays expressed as the relative coefficient of variation (CV) of the positive control assayed over a 3-year period in the same laboratory was 22.2% for bovines and 23.1% for guinea pigs. The reproducibility of both techniques obtained in inter-laboratory assays was CV=12.4% for bovines and CV approximately 0 for guinea pigs, which met the requirements of the OIE (CV<30%). The validated ELISAs represent important methods for vaccine potency testing and for controlling BoHV-1 infections. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  15. Heating Augmentation in Laminar Flow Due to Heat-Shield Cavities on the Project Orion CEV

    NASA Technical Reports Server (NTRS)

    Hollis, Brian R.

    2008-01-01

    An experimental study has been conducted to assess the effects of compression pad cavities on the aeroheating environment of the Project Orion CEV heat-shield at laminar conditions. Testing was conducted in Mach 6 and Mach 10 perfect-gas wind tunnels to obtain heating measurements on and around the compression pads using global phosphor thermography. Consistent trends in heating augmentation levels were observed in the data and correlations of average and maximum heating at the cavities were formulated in terms of the local boundary-layer parameters and cavity dimensions. Additional heating data from prior testing of Genesis and Mars Science Laboratory models were also examined to extend the parametric range of cavity heating correlations.

  16. Chained Bell Inequality Experiment with High-Efficiency Measurements

    NASA Astrophysics Data System (ADS)

    Tan, T. R.; Wan, Y.; Erickson, S.; Bierhorst, P.; Kienzler, D.; Glancy, S.; Knill, E.; Leibfried, D.; Wineland, D. J.

    2017-03-01

    We report correlation measurements on two 9Be+ ions that violate a chained Bell inequality obeyed by any local-realistic theory. The correlations can be modeled as derived from a mixture of a local-realistic probabilistic distribution and a distribution that violates the inequality. A statistical framework is formulated to quantify the local-realistic fraction allowable in the observed distribution without the fair-sampling or independent-and-identical-distributions assumptions. We exclude models of our experiment whose local-realistic fraction is above 0.327 at the 95% confidence level. This bound is significantly lower than 0.586, the minimum fraction derived from a perfect Clauser-Horne-Shimony-Holt inequality experiment. Furthermore, our data provide a device-independent certification of the deterministically created Bell states.

  17. Using the load-velocity relationship for 1RM prediction.

    PubMed

    Jidovtseff, Boris; Harris, Nigel K; Crielaard, Jean-Michel; Cronin, John B

    2011-01-01

    The purpose of this study was to investigate the ability of the load-velocity relationship to accurately predict a bench press 1 repetition maximum (1RM). Data from 3 different bench press studies (n = 112) that incorporated both 1RM assessment and submaximal load-velocity profiling were analyzed. Individual regression analysis was performed to determine the theoretical load at zero velocity (LD0). Data from each of the 3 studies were analyzed separately and also presented as overall group mean. Thereafter, correlation analysis provided quantification of the relationships between 1RM and LD0. Practically perfect correlations (r = ∼0.95) were observed in our samples, confirming the ability of the load-velocity profile to accurately predict bench press 1RM.

  18. Atomic kinetic energy, momentum distribution, and structure of solid neon at zero temperature

    NASA Astrophysics Data System (ADS)

    Cazorla, C.; Boronat, J.

    2008-01-01

    We report on the calculation of the ground-state atomic kinetic energy Ek and momentum distribution of solid Ne by means of the diffusion Monte Carlo method and Aziz HFD-B pair potential. This approach is shown to perform notably for this crystal since we obtain very good agreement with respect to experimental thermodynamic data. Additionally, we study the structural properties of solid Ne at densities near the equilibrium by estimating the radial pair-distribution function, Lindemann’s ratio, and atomic density profile around the positions of the perfect crystalline lattice. Our value for Ek at the equilibrium density is 41.51(6)K , which agrees perfectly with the recent prediction made by Timms , 41(2)K , based on their deep-inelastic neutron scattering experiments carried out over the temperature range 4-20K , and also with previous path integral Monte Carlo results obtained with the Lennard-Jones and Aziz HFD-C2 atomic pairwise interactions. The one-body density function of solid Ne is calculated accurately and found to fit perfectly, within statistical uncertainty, to a Gaussian curve. Furthermore, we analyze the degree of anharmonicity of solid Ne by calculating some of its microscopic ground-state properties within traditional harmonic approaches. We provide insightful comparison to solid He4 in terms of the Debye model in order to assess the relevance of anharmonic effects in Ne.

  19. Chaos in quantum channels

    DOE PAGES

    Hosur, Pavan; Qi, Xiao-Liang; Roberts, Daniel A.; ...

    2016-02-01

    For this research, we study chaos and scrambling in unitary channels by considering their entanglement properties as states. Using out-of-time-order correlation functions to diagnose chaos, we characterize the ability of a channel to process quantum information. We show that the generic decay of such correlators implies that any input subsystem must have near vanishing mutual information with almost all partitions of the output. Additionally, we propose the negativity of the tripartite information of the channel as a general diagnostic of scrambling. This measures the delocalization of information and is closely related to the decay of out-of-time-order correlators. We back upmore » our results with numerics in two non-integrable models and analytic results in a perfect tensor network model of chaotic time evolution. In conclusion, these results show that the butterfly effect in quantum systems implies the information-theoretic definition of scrambling.« less

  20. Wavelet transform: fundamentals, applications, and implementation using acousto-optic correlators

    NASA Astrophysics Data System (ADS)

    DeCusatis, Casimer M.; Koay, J.; Litynski, Daniel M.; Das, Pankaj K.

    1995-10-01

    In recent years there has been a great deal of interest in the use of wavelets to supplement or replace conventional Fourier transform signal processing. This paper provides a review of wavelet transforms for signal processing applications, and discusses several emerging applications which benefit from the advantages of wavelets. The wavelet transform can be implemented as an acousto-optic correlator; perfect reconstruction of digital signals may also be achieved using acousto-optic finite impulse response filter banks. Acousto-optic image correlators are discussed as a potential implementation of the wavelet transform, since a 1D wavelet filter bank may be encoded as a 2D image. We discuss applications of the wavelet transform including nondestructive testing of materials, biomedical applications in the analysis of EEG signals, and interference excision in spread spectrum communication systems. Computer simulations and experimental results for these applications are also provided.

  1. The Perfect Aspect as a State of Being.

    ERIC Educational Resources Information Center

    Moy, Raymond H.

    English as second language (ESL) learners often avoid using the present perfect or use it improperly. In contrast with native speakers of English sampled from newspaper editorials, of whom 75 percent used the present perfect, only 22 percent of ESL college students used the present perfect correctly. This avoidance is due in part to lack of…

  2. Practice makes perfect in memory recall.

    PubMed

    Romani, Sandro; Katkov, Mikhail; Tsodyks, Misha

    2016-04-01

    A large variability in performance is observed when participants recall briefly presented lists of words. The sources of such variability are not known. Our analysis of a large data set of free recall revealed a small fraction of participants that reached an extremely high performance, including many trials with the recall of complete lists. Moreover, some of them developed a number of consistent input-position-dependent recall strategies, in particular recalling words consecutively ("chaining") or in groups of consecutively presented words ("chunking"). The time course of acquisition and particular choice of positional grouping were variable among participants. Our results show that acquiring positional strategies plays a crucial role in improvement of recall performance. © 2016 Romani et al.; Published by Cold Spring Harbor Laboratory Press.

  3. Dual of the Janus solution: An interface conformal field theory

    NASA Astrophysics Data System (ADS)

    Clark, A. B.; Freedman, D. Z.; Karch, A.; Schnabl, M.

    2005-03-01

    We propose and study a specific gauge theory dual of the smooth, nonsupersymmetric (and apparently stable) Janus solution of Type IIB supergravity found in Bak et al. [J. High Energy Phys., JHEPFG, 1029-8479 05 (2003) 072]. The dual field theory is N=4 SYM theory on two half-spaces separated by a planar interface with different coupling constants in each half-space. We assume that the position dependent coupling multiplies the operator L' which is the fourth descendent of the primary TrX{IXJ} and closely related to the N=4 Lagrangian density. At the classical level supersymmetry is broken explicitly, but SO(3,2) conformal symmetry is preserved. We use conformal perturbation theory to study various correlation functions to first and second order in the discontinuity of g2YM, confirming quantum level conformal symmetry. Certain quantities such as the vacuum expectation value are protected to all orders in g2YMN, and we find perfect agreement between the weak coupling value in the gauge theory and the strong coupling gravity result. SO(3,2) symmetry requires vanishing vacuum energy, =0, and this is confirmed in first order in the discontinuity.

  4. No Improvement in Sprint Performance With a Neuromuscular Fitted Dental Splint.

    PubMed

    Fischer, Henrike; Weber, Daniel; Beneke, Ralph

    2017-03-01

    Mouth guards protect against orofacial and dental injuries in sports. However, special fitted dental splints have been claimed to improve strength and speed and, therefore, to enhance athletic performance. To test the effects of a neuromuscular fitted dental splint in comparison with a habitual verticalizing splint and a no-splint condition on cycling sprint performance in the Wingate Anaerobic Test (WAnT). Twenty-three men (26.0 ± 2.0 y, 1.82 ± 0.06 m, 79.4 ± 7.7 kg) performed 3 WAnTs, 1 with the neuromuscular fitted splint, 1 with a habitual verticalized dental splint of the same height and material, and 1 under control conditions without any mouth guard, in randomized order separated by 1 wk. No differences between any splint conditions were found in any aspect of WAnT performance (time to peak power, peak power, minimum power, power drop, and average power). Moderate to nearly perfect correlations between all splint conditions in all WAnT outcomes with coefficients of variation between 1.3% and 6.6% were found. Irrespective of habitual verticalization or myocentric positioning, dental splints have no effects on any aspect of WAnT performance. Results are comparable to those of test-retest experiments.

  5. High precision position sensor based on CPA in a composite multi-layered system.

    PubMed

    Dey, Sanjeeb; Singh, Suneel; Rao, Desai Narayana

    2018-04-16

    We propose a scheme for high precision position sensing based on coherent perfect absorption (CPA) in a five-layered structure comprising three layers of metal-dielectric composites and two spacer (air) layers. Both the outermost interfaces of the five layered medium are irradiated by two identical coherent light waves at the same angle of incidence. We first investigate the occurrence of CPA in a symmetric layered structure as a function of different system parameters for oblique incidence. Thereafter, by shifting the middle layer, beginning from one end of the structure to the other, we observe the periodic occurrence of extremely narrow CPA resonances at several positions of the middle layer. Moreover this phenomenon is seen to recur even at many other wavelengths. We discuss how the position sensitivity of this phenomenon can be utilized for designing a CPA based high precision position sensing device.

  6. [Roaming through methodology. XXXII. False test results].

    PubMed

    van der Weijden, T; van den Akker, M

    2001-05-12

    The number of requests for diagnostic tests is rising. This leads to a higher chance of false test results. The false-negative proportion of a test is the proportion of negative test results among the diseased subjects. The false-positive proportion is the proportion of positive test results among the healthy subjects. The calculation of the false-positive proportion is often incorrect. For example, instead of 1 minus the specificity it is calculated as 1 minus the positive predictive value. This can lead to incorrect decision-making with respect to the application of the test. Physicians must apply diagnostic tests in such a way that the risk of false test results is minimal. The patient should be aware that a perfectly conclusive diagnostic test is rare in medical practice, and should more often be informed of the implications of false-positive and false-negative test results.

  7. Correlation of photon pairs from the double Raman amplifier: Generalized analytical quantum Langevin theory

    NASA Astrophysics Data System (ADS)

    Raymond Ooi, C. H.; Sun, Qingqing; Zubairy, M. Suhail; Scully, Marlan O.

    2007-01-01

    We present a largely analytical theory for two-photon correlations G(2) between Stokes (s) and anti-Stokes (a) photon pairs from an extended medium (amplifier) composed of double- Λ atoms in counterpropagating geometry. We generalize the parametric coupled equations with quantum Langevin noise given in a beautiful experimental paper of Balic [Phys. Rev. Lett. 94, 183601 (2005)] beyond adiabatic approximation and valid for arbitrary strength and detuning of laser fields. We derive an analytical formula for cross correlation Gas(2)=⟨Ês†(L)Êa†(0,τ)Êa(0,τ)Ês(L)⟩ and use it to obtain results that are in good quantitative agreement with the experimental data. Results for Gas(2) obtained using our coupled equations are in good quantitative agreement with the results using the equations of Balic , while perfect agreement is obtained for sufficiently large detuning. We also compute the reverse correlation Gsa(2) which turns out to be negligibly small and remains classical while the cross correlation violates the Cauchy-Schwartz inequality by a factor of more than a hundred.

  8. Flower-like heads from flower-like meristems: pseudanthium development in Davidia involucrata (Nyssaceae).

    PubMed

    Claßen-Bockhoff, Regine; Arndt, Melanie

    2018-05-01

    Flower-like inflorescences (pseudanthia) have fascinated botanists for a long time. They are explained as condensed inflorescences implying that the pseudanthium develops from an inflorescence meristem (IM). However, recent developmental studies identified a new form of reproductive meristem, the floral unit meristem (FUM). It differs from IMs by lacking acropetal growth and shares fractionation, expansion and autonomous space filling with flower meristems (FM). The similarity among FUMs and FMs raises the question how far flower-like heads originate from flower-like meristems. In the present paper, pseudanthium development in Davidia involucrata is investigated using scanning electron microscopy. D. involucrata has pincushion-shaped heads composed of densely aggregated, perianthless flowers and associated with two large showy bracts. Early developmental stages show a huge naked FUM. The FMs appear almost simultaneously and lack subtending bracts. With ongoing FUM expansion new space is generated which is immediately used by further FM fractionation. The heads have only staminate flowers or are andromonoecious with staminate and a single perfect flower in oblique position. All FMs lack perianth structures and fractionate a variable number of stamen primordia. The perfect FM is much larger than the staminate FMs and forms a syncarpous gynoecium with inferior ovary. Pseudanthium development in D. involucrata confirms the morphogenetic similarity to FMs as to acropetal growth limitation, meristem expansion and fractionation. It thus should not be interpreted as a condensed inflorescence, but as a flower equivalent. Furthermore as the FUM develops inside a bud, its development is considered to be influenced by mechanical pressure. The oblique position of the perfect flower, the developmental delay of the proximal flowers, and the variable number of stamens which were observed in the pseudanthium development, can be caused by mechanical pressure. Next to the Asteraceae, D. involucrata offers a further example of a pseudanthium originating from a FUM. More knowledge on FUMs is still needed to understand diversification and evolution of flower-like inflorescences.

  9. Computation of Thermally Perfect Compressible Flow Properties

    NASA Technical Reports Server (NTRS)

    Witte, David W.; Tatum, Kenneth E.; Williams, S. Blake

    1996-01-01

    A set of compressible flow relations for a thermally perfect, calorically imperfect gas are derived for a value of c(sub p) (specific heat at constant pressure) expressed as a polynomial function of temperature and developed into a computer program, referred to as the Thermally Perfect Gas (TPG) code. The code is available free from the NASA Langley Software Server at URL http://www.larc.nasa.gov/LSS. The code produces tables of compressible flow properties similar to those found in NACA Report 1135. Unlike the NACA Report 1135 tables which are valid only in the calorically perfect temperature regime the TPG code results are also valid in the thermally perfect, calorically imperfect temperature regime, giving the TPG code a considerably larger range of temperature application. Accuracy of the TPG code in the calorically perfect and in the thermally perfect, calorically imperfect temperature regimes are verified by comparisons with the methods of NACA Report 1135. The advantages of the TPG code compared to the thermally perfect, calorically imperfect method of NACA Report 1135 are its applicability to any type of gas (monatomic, diatomic, triatomic, or polyatomic) or any specified mixture of gases, ease-of-use, and tabulated results.

  10. HPHT growth and x-ray characterization of high-quality type IIa diamond.

    PubMed

    Burns, R C; Chumakov, A I; Connell, S H; Dube, D; Godfried, H P; Hansen, J O; Härtwig, J; Hoszowska, J; Masiello, F; Mkhonza, L; Rebak, M; Rommevaux, A; Setshedi, R; Van Vaerenbergh, P

    2009-09-09

    The trend in synchrotron radiation (x-rays) is towards higher brilliance. This may lead to a very high power density, of the order of hundreds of watts per square millimetre at the x-ray optical elements. These elements are, typically, windows, polarizers, filters and monochromators. The preferred material for Bragg diffracting optical elements at present is silicon, which can be grown to a very high crystal perfection and workable size as well as rather easily processed to the required surface quality. This allows x-ray optical elements to be built with a sufficient degree of lattice perfection and crystal processing that they may preserve transversal coherence in the x-ray beam. This is important for the new techniques which include phase-sensitive imaging experiments like holo-tomography, x-ray photon correlation spectroscopy, coherent diffraction imaging and nanofocusing. Diamond has a lower absorption coefficient than silicon, a better thermal conductivity and lower thermal expansion coefficient which would make it the preferred material if the crystal perfection (bulk and surface) could be improved. Synthetic HPHT-grown (high pressure, high temperature) type Ib material can readily be produced in the necessary sizes of 4-8 mm square and with a nitrogen content of typically a few hundred parts per million. This material has applications in the less demanding roles such as phase plates: however, in a coherence-preserving beamline, where all elements must be of the same high quality, its quality is far from sufficient. Advances in HPHT synthesis methods have allowed the growth of type IIa diamond crystals of the same size as type Ib, but with substantially lower nitrogen content. Characterization of this high purity type IIa material has been carried out with the result that the crystalline (bulk) perfection of some of the HPHT-grown materials is approaching the quality required for the more demanding applications such as imaging applications and imaging applications with coherence preservation. The targets for further development of the type IIa diamond are size, crystal perfection, as measured by the techniques of white beam and monochromatic x-ray diffraction imaging (historically called x-ray topography), and also surface quality. Diamond plates extracted from the cubic growth sector furthest from the seed of the new low strain material produces no measurable broadening of the x-ray rocking curve width. One measures essentially the crystal reflectivity as defined by the intrinsic reflectivity curve (Darwin curve) width of a perfect crystal. In these cases the more sensitive technique of plane wave topography has been used to establish a local upper limit of the strain at the level of an 'effective misorientation' of 10(-7) rad.

  11. Capturing the crystalline phase of two-dimensional nanocrystal superlattices in action.

    PubMed

    Jiang, Zhang; Lin, Xiao-Min; Sprung, Michael; Narayanan, Suresh; Wang, Jin

    2010-03-10

    Critical photonic, electronic, and magnetic applications of two-dimensional nanocrystal superlattices often require nanostructures in perfect single-crystal phases with long-range order and limited defects. Here we discovered a crystalline phase with quasi-long-range positional order for two-dimensional nanocrystal superlattice domains self-assembled at the liquid-air interface during droplet evaporation, using in situ time-resolved X-ray scattering along with rigorous theories on two dimensional crystal structures. Surprisingly, it was observed that drying these superlattice domains preserved only an orientational order but not a long-range positional order, also supported by quantitative analysis of transmission electron microscopy images.

  12. The Infrared & Electro-Optical Systems Handbook. Emerging Systems and Technologies, Volume 8

    DTIC Science & Technology

    1993-01-01

    usually associated with turbulence in the intervening path or to significant nonuniformities in com- position or temperature of the air within the field of...cause beam quality to be less than perfect. Coatings on the mirrors can also be nonuniform , leading to further OPD effects. Resonator misalignment...despite an undesired spherical error). Coatings can be nonuniform in their thickness. This thickness nonuniform - ity is equivalent to a mirror fabrication

  13. Growth and characterization of AgGa0.5In0.5Se2 single crystals by modified vertical Bridgman method

    NASA Astrophysics Data System (ADS)

    Vijayakumar, P.; Ramasamy, P.

    2016-05-01

    AgGa0.5In0.5Se2 single crystal was grown using a double wall quartz ampoule with accelerated crucible rotation technique by modified vertical Bridgman method. The structural perfection was measured using HRXRD. The grown single crystal composition was measured using ICP-OES analysis and compositional uniformities were measured using Raman spectroscopy analysis. Photoconductivity measurements confirm the positive photoconducting nature.

  14. Advancing the education of nurses: a call for action.

    PubMed

    Zimmermann, Deborah T; Miner, Dianne Cooney; Zittel, Barbara

    2010-12-01

    The debate over the educational preparation of RNs has raged for over a century. In New York, chief nursing officers are partnering with academic colleagues and successfully implementing a model that standardizes education requirements, supports seamless transition from associate to baccalaureate degree programs, addresses financial barriers, and identifies expected outcomes of a more educated workforce. Nursing leaders are perfectly positioned to advance the educational standards of the profession in the United States.

  15. Professional nursing burnout and irrational thinking.

    PubMed

    Balevre, P

    2001-01-01

    This article reports how professional, job-related burnout in nurses (N = 192) is examined in relation to a developed index of irrational thinking patterns in a large, urban hospital setting. Based on the constructs of Rational Emotive Behavior Therapy (REBT), the study examines maladaptive thinking patterns related to nursing burnout and provides insight into possible educational and staff interventions for the syndrome. Low mean scores on all but two subscales indicate overall strength and stability among this sample. The demonstration that both burnout thoughts (r = 0.451, p = < .01) and burnout behaviors (r = 0.350, p = < .01) are significantly correlated with the perfection and control pattern support the study's assumptions. Nurses who demand perfection and control in themselves and others create unrealistic demands and expectations that cannot be met in the real world of nursing. The investigator believes that a regular stress management program, using the concepts of REBT, can foster professional growth and development, decrease workplace conflict and stress, and provide nurses (and other employees) with strategies and tools to disarm the irrational beliefs that build maladaptive cognitive patterns leading to professional burnout.

  16. The growth and perfection of β-cyclotetramethylene-tetranitramine (HMX) studied by laboratory and synchrotron X-ray topography

    NASA Astrophysics Data System (ADS)

    Gallagher, H. G.; Sherwood, J. N.; Vrcelj, R. M.

    2017-10-01

    An examination has been made of the defect structure of crystals of the energetic material β-cyclotetramethylene-tetranitramine (HMX) using both Laboratory (Lang method) and Synchrotron (Bragg Reflection and Laue method) techniques. The results of the three methods are compared with particular attention to the influence of potential radiation damage caused to the samples by the latter, more energetic, technique. The comparison shows that both techniques can be confidently used to evaluate the defect structures yielding closely similar results. The results show that, even under the relatively casual preparative methods used (slow evaporation of unstirred solutions at constant temperature), HMX crystals of high perfection can be produced. The crystals show well defined bulk defect structures characteristic of organic materials in general: growth dislocations, twins, growth sector boundaries, growth banding and solvent inclusions. The distribution of the defects in specific samples is correlated with the morphological variation of the grown crystals. The results show promise for the further evaluation and characterisation of the structure and properties of dislocations and other defects and their involvement in mechanical and energetic processes in this material.

  17. An approximate Riemann solver for thermal and chemical nonequilibrium flows

    NASA Technical Reports Server (NTRS)

    Prabhu, Ramadas K.

    1994-01-01

    Among the many methods available for the determination of inviscid fluxes across a surface of discontinuity, the flux-difference-splitting technique that employs Roe-averaged variables has been used extensively by the CFD community because of its simplicity and its ability to capture shocks exactly. This method, originally developed for perfect gas flows, has since been extended to equilibrium as well as nonequilibrium flows. Determination of the Roe-averaged variables for the case of a perfect gas flow is a simple task; however, for thermal and chemical nonequilibrium flows, some of the variables are not uniquely defined. Methods available in the literature to determine these variables seem to lack sound bases. The present paper describes a simple, yet accurate, method to determine all the variables for nonequilibrium flows in the Roe-average state. The basis for this method is the requirement that the Roe-averaged variables form a consistent set of thermodynamic variables. The present method satisfies the requirement that the square of the speed of sound be positive.

  18. Evidence for Precise Calendrical Observations in the 17th Century at the `Bruchhauser Steine', Olsberg, Northrhine-Westphalia, Germany

    NASA Astrophysics Data System (ADS)

    Steinrücken, B.

    The `Bruchhauser Steine', four large rocks of volcanic origin in southern Westphalia, form perfect foresights for calendrical observations from the surrounding country. The ancient walls and embankments on the `Istenberg' with the rocks as cornerstones were built 500 BC. In the landscape are placed shrines with images of Christian saints, erected in the late 17th and the early 18th century. The positions of these shrines can be interpreted as observing sites with respect to the stones. The foresights reach several degrees to the sky, so variations in the astronomical refraction are strongly suppressed. The most impressive observing site with a shrine of 1699 (8o31'13'' E, 51o18'49'' N) is exactly at the position to observe the summer solstice sunrise at the topmost rock, the `Feldstein'. The solstice sun rises between two stones and grazes the Feldstein at 6:20 CEST. Today the sun is obstructed 2'-3' by the stone. Taking into account the slight variation of the obliquity of the ecliptic of 2' since 1699 the grazing procedure at the time of erection was perfect, without any obstruction of the suns disc. Similar shrines are placed at positions to observe the sunrise on May 1st in the identical manner (8o29'39'' E, 51o18'41'' N) and the lunar declination minimum on the meridian (8o32'44'' E, 51o20'33'' N). Some evidence indicates a prehistoric origin of this calendrical system.

  19. ChloroSSRdb: a repository of perfect and imperfect chloroplastic simple sequence repeats (cpSSRs) of green plants

    PubMed Central

    Kapil, Aditi; Rai, Piyush Kant; Shanker, Asheesh

    2014-01-01

    Simple sequence repeats (SSRs) are regions in DNA sequence that contain repeating motifs of length 1–6 nucleotides. These repeats are ubiquitously present and are found in both coding and non-coding regions of genome. A total of 534 complete chloroplast genome sequences (as on 18 September 2014) of Viridiplantae are available at NCBI organelle genome resource. It provides opportunity to mine these genomes for the detection of SSRs and store them in the form of a database. In an attempt to properly manage and retrieve chloroplastic SSRs, we designed ChloroSSRdb which is a relational database developed using SQL server 2008 and accessed through ASP.NET. It provides information of all the three types (perfect, imperfect and compound) of SSRs. At present, ChloroSSRdb contains 124 430 mined SSRs, with majority lying in non-coding region. Out of these, PCR primers were designed for 118 249 SSRs. Tetranucleotide repeats (47 079) were found to be the most frequent repeat type, whereas hexanucleotide repeats (6414) being the least abundant. Additionally, in each species statistical analyses were performed to calculate relative frequency, correlation coefficient and chi-square statistics of perfect and imperfect SSRs. In accordance with the growing interest in SSR studies, ChloroSSRdb will prove to be a useful resource in developing genetic markers, phylogenetic analysis, genetic mapping, etc. Moreover, it will serve as a ready reference for mined SSRs in available chloroplast genomes of green plants. Database URL: www.compubio.in/chlorossrdb/ PMID:25380781

  20. ChloroSSRdb: a repository of perfect and imperfect chloroplastic simple sequence repeats (cpSSRs) of green plants.

    PubMed

    Kapil, Aditi; Rai, Piyush Kant; Shanker, Asheesh

    2014-01-01

    Simple sequence repeats (SSRs) are regions in DNA sequence that contain repeating motifs of length 1-6 nucleotides. These repeats are ubiquitously present and are found in both coding and non-coding regions of genome. A total of 534 complete chloroplast genome sequences (as on 18 September 2014) of Viridiplantae are available at NCBI organelle genome resource. It provides opportunity to mine these genomes for the detection of SSRs and store them in the form of a database. In an attempt to properly manage and retrieve chloroplastic SSRs, we designed ChloroSSRdb which is a relational database developed using SQL server 2008 and accessed through ASP.NET. It provides information of all the three types (perfect, imperfect and compound) of SSRs. At present, ChloroSSRdb contains 124 430 mined SSRs, with majority lying in non-coding region. Out of these, PCR primers were designed for 118 249 SSRs. Tetranucleotide repeats (47 079) were found to be the most frequent repeat type, whereas hexanucleotide repeats (6414) being the least abundant. Additionally, in each species statistical analyses were performed to calculate relative frequency, correlation coefficient and chi-square statistics of perfect and imperfect SSRs. In accordance with the growing interest in SSR studies, ChloroSSRdb will prove to be a useful resource in developing genetic markers, phylogenetic analysis, genetic mapping, etc. Moreover, it will serve as a ready reference for mined SSRs in available chloroplast genomes of green plants. Database URL: www.compubio.in/chlorossrdb/ © The Author(s) 2014. Published by Oxford University Press.

  1. Reliability of a rapid hematology stain for sputum cytology*

    PubMed Central

    Gonçalves, Jéssica; Pizzichini, Emilio; Pizzichini, Marcia Margaret Menezes; Steidle, Leila John Marques; Rocha, Cristiane Cinara; Ferreira, Samira Cardoso; Zimmermann, Célia Tânia

    2014-01-01

    Objective: To determine the reliability of a rapid hematology stain for the cytological analysis of induced sputum samples. Methods: This was a cross-sectional study comparing the standard technique (May-Grünwald-Giemsa stain) with a rapid hematology stain (Diff-Quik). Of the 50 subjects included in the study, 21 had asthma, 19 had COPD, and 10 were healthy (controls). From the induced sputum samples collected, we prepared four slides: two were stained with May-Grünwald-Giemsa, and two were stained with Diff-Quik. The slides were read independently by two trained researchers blinded to the identification of the slides. The reliability for cell counting using the two techniques was evaluated by determining the intraclass correlation coefficients (ICCs) for intraobserver and interobserver agreement. Agreement in the identification of neutrophilic and eosinophilic sputum between the observers and between the stains was evaluated with kappa statistics. Results: In our comparison of the two staining techniques, the ICCs indicated almost perfect interobserver agreement for neutrophil, eosinophil, and macrophage counts (ICC: 0.98-1.00), as well as substantial agreement for lymphocyte counts (ICC: 0.76-0.83). Intraobserver agreement was almost perfect for neutrophil, eosinophil, and macrophage counts (ICC: 0.96-0.99), whereas it was moderate to substantial for lymphocyte counts (ICC = 0.65 and 0.75 for the two observers, respectively). Interobserver agreement for the identification of eosinophilic and neutrophilic sputum using the two techniques ranged from substantial to almost perfect (kappa range: 0.91-1.00). Conclusions: The use of Diff-Quik can be considered a reliable alternative for the processing of sputum samples. PMID:25029648

  2. Similarities between principal components of protein dynamics and random diffusion

    NASA Astrophysics Data System (ADS)

    Hess, Berk

    2000-12-01

    Principal component analysis, also called essential dynamics, is a powerful tool for finding global, correlated motions in atomic simulations of macromolecules. It has become an established technique for analyzing molecular dynamics simulations of proteins. The first few principal components of simulations of large proteins often resemble cosines. We derive the principal components for high-dimensional random diffusion, which are almost perfect cosines. This resemblance between protein simulations and noise implies that for many proteins the time scales of current simulations are too short to obtain convergence of collective motions.

  3. All-versus-nothing proofs with n qubits distributed between m parties

    NASA Astrophysics Data System (ADS)

    Cabello, Adán; Moreno, Pilar

    2010-04-01

    All-versus-nothing (AVN) proofs show the conflict between Einstein, Podolsky, and Rosen’s elements of reality and the perfect correlations of some quantum states. Given an n-qubit state distributed between m parties, we provide a method with which to decide whether this distribution allows an m-partite AVN proof specific for this state using only single-qubit measurements. We apply this method to some recently obtained n-qubit m-particle states. In addition, we provide all inequivalent AVN proofs with less than nine qubits and a minimum number of parties.

  4. Entropy/information flux in Hawking radiation

    NASA Astrophysics Data System (ADS)

    Alonso-Serrano, Ana; Visser, Matt

    2018-01-01

    Blackbody radiation contains (on average) an entropy of 3.9 ± 2.5 bits per photon. If the emission process is unitary, then this entropy is exactly compensated by "hidden information" in the correlations. We extend this argument to the Hawking radiation from GR black holes, demonstrating that the assumption of unitarity leads to a perfectly reasonable entropy/information budget. The key technical aspect of our calculation is a variant of the "average subsystem" approach developed by Page, which we extend beyond bipartite pure systems, to a tripartite pure system that considers the influence of the environment.

  5. "Evaluations" of Observables Versus Measurements in Quantum Theory

    NASA Astrophysics Data System (ADS)

    Nisticò, Giuseppe; Sestito, Angela

    2016-03-01

    In Quantum Physics there are circumstances where the direct measurement of a given observable encounters difficulties; in some of these cases, however, its value can be "evaluated", i.e. it can be inferred by measuring another observable characterized by perfect correlation with the observable of interest. Though an evaluation is often interpreted as a measurement of the evaluated observable, we prove that the two concepts cannot be identified in Quantum Physics, because the identification yields contradictions. Then, we establish the conceptual status of evaluations in Quantum Theory and how they are related to measurements.

  6. Flow structure and heat exchange analysis in internal cooling channel of gas turbine blade

    NASA Astrophysics Data System (ADS)

    Szwaba, Ryszard; Kaczynski, Piotr; Doerffer, Piotr; Telega, Janusz

    2016-08-01

    This paper presents the study of the flow structure and heat transfer, and also their correlations on the four walls of a radial cooling passage model of a gas turbine blade. The investigations focus on heat transfer and aerodynamic measurements in the channel, which is an accurate representation of the configuration used in aeroengines. Correlations for the heat transfer coefficient and the pressure drop used in the design of radial cooling passages are often developed from simplified models. It is important to note that real engine passages do not have perfect rectangular cross sections, but include corner fillet, ribs with fillet radii and special orientation. Therefore, this work provides detailed fluid flow and heat transfer data for a model of radial cooling geometry which possesses very realistic features.

  7. Iridium-catalyzed direct tetraborylation of perylene bisimides.

    PubMed

    Teraoka, Takuro; Hiroto, Satoru; Shinokubo, Hiroshi

    2011-05-20

    Treatment of perylene bisimides (PBIs) with bis(pinacolato)diboron in the presence of an iridium catalyst provides tetraborylated PBIs at 2,5,8,11-positions in good yields with perfect regioselectivity. The planar structure of the perylene core has been confirmed by X-ray diffraction analysis. Oxidation of tetraborylated PBI with hydroxylamine hydrochloride affords tetrahydroxy PBI in excellent yield, which exhibits a substantially blue-shifted absorption spectrum due to an intramolecular hydrogenbonding interaction between carbonyl and hydroxy groups.

  8. Biseparability of noisy pseudopure, W and GHZ states using conditional quantum relative Tsallis entropy

    NASA Astrophysics Data System (ADS)

    Nayak, Anantha S.; Sudha; Usha Devi, A. R.; Rajagopal, A. K.

    2017-02-01

    We employ the conditional version of sandwiched Tsallis relative entropy to determine 1:N-1 separability range in the noisy one-parameter families of pseudopure and Werner-like N-qubit W, GHZ states. The range of the noisy parameter, for which the conditional sandwiched Tsallis relative entropy is positive, reveals perfect agreement with the necessary and sufficient criteria for separability in the 1:N-1 partition of these one parameter noisy states.

  9. Plug-In Electric Vehicle Handbook for Workplace Charging Hosts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2013-08-01

    Plug-in electric vehicles (PEVs) have immense potential for increasing the country's energy, economic, and environmental security, and they will play a key role in the future of U.S. transportation. By providing PEV charging at the workplace, employers are perfectly positioned to contribute to and benefit from the electrification of transportation. This handbook answers basic questions about PEVs and charging equipment, helps employers assess whether to offer workplace charging for employees, and outlines important steps for implementation.

  10. Template-directed atomically precise self-organization of perfectly ordered parallel cerium silicide nanowire arrays on Si(110)-16 × 2 surfaces.

    PubMed

    Hong, Ie-Hong; Liao, Yung-Cheng; Tsai, Yung-Feng

    2013-11-05

    The perfectly ordered parallel arrays of periodic Ce silicide nanowires can self-organize with atomic precision on single-domain Si(110)-16 × 2 surfaces. The growth evolution of self-ordered parallel Ce silicide nanowire arrays is investigated over a broad range of Ce coverages on single-domain Si(110)-16 × 2 surfaces by scanning tunneling microscopy (STM). Three different types of well-ordered parallel arrays, consisting of uniformly spaced and atomically identical Ce silicide nanowires, are self-organized through the heteroepitaxial growth of Ce silicides on a long-range grating-like 16 × 2 reconstruction at the deposition of various Ce coverages. Each atomically precise Ce silicide nanowire consists of a bundle of chains and rows with different atomic structures. The atomic-resolution dual-polarity STM images reveal that the interchain coupling leads to the formation of the registry-aligned chain bundles within individual Ce silicide nanowire. The nanowire width and the interchain coupling can be adjusted systematically by varying the Ce coverage on a Si(110) surface. This natural template-directed self-organization of perfectly regular parallel nanowire arrays allows for the precise control of the feature size and positions within ±0.2 nm over a large area. Thus, it is a promising route to produce parallel nanowire arrays in a straightforward, low-cost, high-throughput process.

  11. Template-directed atomically precise self-organization of perfectly ordered parallel cerium silicide nanowire arrays on Si(110)-16 × 2 surfaces

    PubMed Central

    2013-01-01

    The perfectly ordered parallel arrays of periodic Ce silicide nanowires can self-organize with atomic precision on single-domain Si(110)-16 × 2 surfaces. The growth evolution of self-ordered parallel Ce silicide nanowire arrays is investigated over a broad range of Ce coverages on single-domain Si(110)-16 × 2 surfaces by scanning tunneling microscopy (STM). Three different types of well-ordered parallel arrays, consisting of uniformly spaced and atomically identical Ce silicide nanowires, are self-organized through the heteroepitaxial growth of Ce silicides on a long-range grating-like 16 × 2 reconstruction at the deposition of various Ce coverages. Each atomically precise Ce silicide nanowire consists of a bundle of chains and rows with different atomic structures. The atomic-resolution dual-polarity STM images reveal that the interchain coupling leads to the formation of the registry-aligned chain bundles within individual Ce silicide nanowire. The nanowire width and the interchain coupling can be adjusted systematically by varying the Ce coverage on a Si(110) surface. This natural template-directed self-organization of perfectly regular parallel nanowire arrays allows for the precise control of the feature size and positions within ±0.2 nm over a large area. Thus, it is a promising route to produce parallel nanowire arrays in a straightforward, low-cost, high-throughput process. PMID:24188092

  12. Bose-Einstein correlation within the framework of hadronic mechanics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burande, Chandrakant S.

    The Bose-Einstein correlation is the phenomenon in which protons and antiprotons collide at extremely high energies; coalesce one into the other resulting into the fireball of finite dimension. They annihilate each other and produces large number of mesons that remain correlated at distances very large compared to the size of the fireball. It was believed that Einstein’s special relativity and relativistic quantum mechanics are the valid frameworks to represent this phenomenon. Although, these frameworks are incomplete and require arbitrary parameters (chaoticity) to fit the experimental data which are prohibited by the basic axioms of relativistic quantum mechanics, such as thatmore » for the vacuum expectation values. Moreover, correlated mesons can not be treated as a finite set of isolated point-like particles because it is non-local event due to overlapping of wavepackets. Therefore, the Bose-Einstein correlation is incompatible with the axiom of expectation values of quantum mechanics. In contrary, relativistic hadronic mechanics constructed by Santilli allows an exact representation of the experimental data of the Bose-Einstein correlation and restore the validity of the Lorentz and Poincare symmetries under nonlocal and non-Hamiltonian internal effects. Further, F. Cardone and R. Mignani observed that the Bose-Einstein two-point correlation function derived by Santilli is perfectly matched with experimental data at high energy.« less

  13. How to limit false positives in environmental DNA and metabarcoding?

    PubMed

    Ficetola, Gentile Francesco; Taberlet, Pierre; Coissac, Eric

    2016-05-01

    Environmental DNA (eDNA) and metabarcoding are boosting our ability to acquire data on species distribution in a variety of ecosystems. Nevertheless, as most of sampling approaches, eDNA is not perfect. It can fail to detect species that are actually present, and even false positives are possible: a species may be apparently detected in areas where it is actually absent. Controlling false positives remains a main challenge for eDNA analyses: in this issue of Molecular Ecology Resources, Lahoz-Monfort et al. () test the performance of multiple statistical modelling approaches to estimate the rate of detection and false positives from eDNA data. Here, we discuss the importance of controlling for false detection from early steps of eDNA analyses (laboratory, bioinformatics), to improve the quality of results and allow an efficient use of the site occupancy-detection modelling (SODM) framework for limiting false presences in eDNA analysis. © 2016 John Wiley & Sons Ltd.

  14. Computed tomography arthrography using a radial plane view for the detection of triangular fibrocartilage complex foveal tears.

    PubMed

    Moritomo, Hisao; Arimitsu, Sayuri; Kubo, Nobuyuki; Masatomi, Takashi; Yukioka, Masao

    2015-02-01

    To classify triangular fibrocartilage complex (TFCC) foveal lesions on the basis of computed tomography (CT) arthrography using a radial plane view and to correlate the CT arthrography results with surgical findings. We also tested the interobserver and intra-observer reliability of the radial plane view. A total of 33 patients with a suspected TFCC foveal tear who had undergone wrist CT arthrography and subsequent surgical exploration were enrolled. We classified the configurations of TFCC foveal lesions into 5 types on the basis of CT arthrography with the radial plane view in which the image slices rotate clockwise centered on the ulnar styloid process. Sensitivity, specificity, and positive predictive values were calculated for each type of foveal lesion in CT arthrography to detect foveal tears. We determined interobserver and intra-observer agreements using kappa statistics. We also compared accuracies with the radial plane views with those with the coronal plane views. Among the tear types on CT arthrography, type 3, a roundish defect at the fovea, and type 4, a large defect at the overall ulnar insertion, had high specificity and positive predictive value for the detection of foveal tears. Specificity and positive predictive values were 90% and 89% for type 3 and 100% and 100% for type 4, respectively, whereas sensitivity was 35% for type 3 and 22% for type 4. Interobserver and intra-observer agreement was substantial and almost perfect, respectively. The radial plane view identified foveal lesion of each palmar and dorsal radioulnar ligament separately, but accuracy results with the radial plane views were not statistically different from those with the coronal plane views. Computed tomography arthrography with a radial plane view exhibited enhanced specificity and positive predictive value when a type 3 or 4 lesion was identified in the detection of a TFCC foveal tear compared with historical controls. Diagnostic II. Copyright © 2015 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  15. Mechanisms of cooperation and competition of two-species transport in narrow nanochannels

    NASA Astrophysics Data System (ADS)

    Bauer, Wolfgang Rudolf

    2017-12-01

    Flow of particles of two different species through a narrow channel with solely two discrete spatial positions is analyzed with respect to the species' capability to cooperate or compete for transport. The origin of the latter arises from particle-channel and interparticle interactions within the channel, i.e., blocking the position of a particle, and its interaction with its neighbors in the channel. The variety of occupation options within the channel defines the state space. The transition dynamics within is considered as a continuous Markov process, which, in contrast to mean-field approaches, conserves explicitly spatial correlations. A strong repulsive interaction between particles of the same kind and a very attractive empty channel imply a strong entanglement of transport of both species. In the limiting case of perfect coupling, flows in state space are restricted to a cyclic subspace, where they become all equivalent in the steady state. In particular, this implies equal particle flows of the two species. Entanglement of transport implies that the species mutually exert entropic forces on each other. For parallel directed concentration gradients this implies that the species' ability to cooperate increases with the degree of entanglement. Thus, the gradient of one species reciprocally induces a higher flow of the other species when compared to that in its absence. The opposite holds for antiparallel gradients where species mutually hamper their transport. For a sufficient strong coupling, the species under the influence of the stronger concentration gradient drives the other against its gradient, i.e., the positive mixing entropy production of the driving species becomes the motor for the negative mixing entropy production of the driven one. The degree of effectiveness by which negative entropy production emerges at the cost of positive entropy production increases with the coupling strength. This becomes evident from location and connectivity of the sources of entropy production in state space.

  16. Comparison among perfect-C®, zero-P®, and plates with a cage in single-level cervical degenerative disc disease.

    PubMed

    Noh, Sung Hyun; Zhang, Ho Yeol

    2018-01-25

    We intended to analyze the efficacy of a new integrated cage and plate device called Perfect-C for anterior cervical discectomy and fusion (ACDF) to cure single-level cervical degenerative disc disease. We enrolled 148 patients who were subjected to single-level ACDF with one of the following three surgical devices: a Perfect-C implant (41 patients), a Zero-P implant (36 patients), or a titanium plate with a polyetheretherketone (PEEK) cage (71 patients). We conducted a retrospective study to compare the clinical and radiological results among the three groups. The length of the operation, intraoperative blood loss, and duration of hospitalization were significantly lower in the Perfect-C group than in the Zero-P and plate-with-cage groups (P < 0.05). At the last follow-up visit, heterotopic ossification (HO) was not observed in any cases (0%) in the Perfect-C and Zero-P groups but was noted in 21 cases (30%) in the plate-with-cage group. The cephalad and caudal plate-to-disc distance (PDD) and the cephalad and caudal PDD/anterior body height (ABH) were significantly greater in the Perfect-C and Zero-P groups than in the plate-with-cage group (P < 0.05). Subsidence occurred in five cases (14%) in the Perfect-C group, in nine cases (25%) in the Zero-P group, and in 15 cases (21%) in the plate-with-cage group. Fusion occurred in 37 cases (90%) in the Perfect-C group, in 31 cases (86%) in the Zero-P group, and in 68 cases (95%) in the plate-with-cage group. The Perfect-C, Zero-P, and plate-with-cage devices are effective for treating single-level cervical degenerative disc disease. However, the Perfect-C implant has many advantages over both the Zero-P implant and conventional plate-cage treatments. The Perfect-C implant was associated with shorter operation times and hospitalization durations, less blood loss, and lower subsidence rates compared with the Zero-P implant or the titanium plate with a PEEK cage.

  17. The relationship between asymmetry, size and unusual venation in honey bees (Apis mellifera).

    PubMed

    Łopuch, S; Tofilski, A

    2016-06-01

    Despite the fact that symmetry is common in nature, it is rarely perfect. Because there is a wide range of phenotypes which differs from the average one, the asymmetry should increase along with deviation. Therefore, the aim of this study was to assess the level of asymmetry in normal individuals as well as in phenodeviants categorized as minor or major based on abnormalities in forewing venation in honey bees. Shape fluctuating asymmetry (FA) was lower in normal individuals and minor phenodeviants compared with major phenodeviants, whereas the former two categories were comparable in drones. In workers and queens, there were not significant differences in FA shape between categories. FA size was significantly lower in normal individuals compared with major phenodeviant drones and higher compared with minor phenodeviant workers. In queens, there were no significant differences between categories. The correlation between FA shape and FA size was significantly positive in drones, and insignificant in workers and queens. Moreover, a considerable level of directional asymmetry was found as the right wing was constantly bigger than the left one. Surprisingly, normal individuals were significantly smaller than minor phenodeviants in queens and drones, and they were comparable with major phenodeviants in all castes. The correlation between wing size and wing asymmetry was negative, indicating that smaller individuals were more asymmetrical. The high proportion of phenodeviants in drones compared with workers and queens confirmed their large variability. Thus, the results of the present study showed that minor phenodeviants were not always intermediate as might have been expected.

  18. Aortitis in giant cell arteritis: diagnosis with FDG PET/CT and agreement with CT angiography.

    PubMed

    Hommada, Mona; Mekinian, Arsène; Brillet, Pierre-Yves; Abad, Sébastien; Larroche, Claire; Dhôte, Robin; Fain, Olivier; Soussan, Michael

    2017-11-01

    To assess the detection rate of aortitis in giant cell arteritis (GCA) with fluorodeoxyglucose positron emission tomography/computed tomography (PET) and to compare the findings with CT angiography (CTA). Fifty-two GCA patients and 27 controls were included. GCA patients had a PET scan at diagnosis (35/52) or during relapse (17/52). Concomitant CTA was performed in 35/52 patients. Aortitis was defined as FDG uptake higher than the liver for PET and wall thickness≥3mm for CTA. Agreement between PET and CTA was evaluated by the kappa coefficient and Spearman correlation coefficient. Aortitis was diagnosed using PET in 40% (14/35) of patients at diagnosis and in 0% of controls (0/27). Agreement was perfect between PET and CT at a patient-based level, and very good at a vascular segment-based level (kappa: 0.72 to 1). PET was positive in 35% (6/17) of patients scanned during GCA relapse, showing aortitis (n=4) and/or articular uptake (n=4). Discrepancies between PET and CT were observed only in relapsing GCA (n=3). Correlation between the maximum standardized uptake value and wall thickness was moderate at diagnosis (r: 0.57 to 0.7) and not statistically significant during relapse. The detection rate of aortitis in GCA patients using PET is 40%, approximately in the range of CTA rates, suggesting that the two techniques have similar sensitivity. PET seems valuable in relapsing GCA, allowing the detection of vascular and articular activities. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Validation of a semi-automatic protocol for the assessment of the tear meniscus central area based on open-source software

    NASA Astrophysics Data System (ADS)

    Pena-Verdeal, Hugo; Garcia-Resua, Carlos; Yebra-Pimentel, Eva; Giraldez, Maria J.

    2017-08-01

    Purpose: Different lower tear meniscus parameters can be clinical assessed on dry eye diagnosis. The aim of this study was to propose and analyse the variability of a semi-automatic method for measuring lower tear meniscus central area (TMCA) by using open source software. Material and methods: On a group of 105 subjects, one video of the lower tear meniscus after fluorescein instillation was generated by a digital camera attached to a slit-lamp. A short light beam (3x5 mm) with moderate illumination in the central portion of the meniscus (6 o'clock) was used. Images were extracted from each video by a masked observer. By using an open source software based on Java (NIH ImageJ), a further observer measured in a masked and randomized order the TMCA in the short light beam illuminated area by two methods: (1) manual method, where TMCA images was "manually" measured; (2) semi-automatic method, where TMCA images were transformed in an 8-bit-binary image, then holes inside this shape were filled and on the isolated shape, the area size was obtained. Finally, both measurements, manual and semi-automatic, were compared. Results: Paired t-test showed no statistical difference between both techniques results (p = 0.102). Pearson correlation between techniques show a significant positive near to perfect correlation (r = 0.99; p < 0.001). Conclusions: This study showed a useful tool to objectively measure the frontal central area of the meniscus in photography by free open source software.

  20. Verification and calibration of laser Doppler flowmetry (LDF) prototype for measurement of microcirculation

    NASA Astrophysics Data System (ADS)

    Li, Yung-Hui; Hu, Chia-Ming; Tsai, Ming-Lun

    2017-10-01

    Laser Doppler Flowmetry (LDF), a non-invasive microcirculation measurement equipment, is designed to be used in measuring microcirculation and perfusion in the skin. LDF is very applicable to healthcare. However, the cost of commercial LDF prevents its prevalence and popularity. In this paper, continuing previous researches, a LDF prototype was built from the combination of the off-the-shelf electronic components. The raw signals acquired from the proposed LDF prototype is validated to be relevant to the microcirculation flux. Furthermore, we would like to verify the consistency between the signals measured from both model, and find an implicit transformation rule to transform the LDF prototype signals. For the purpose of verification and calibration of the LDF prototype signal feature, we first collected a parallel database consisting of flux signals measured by commercial and prototype LDF at the same time. Second, we extract signals with specific frequency of normalized signals as features and use these features to establish a model to allow us to map signals measured by LDF prototype to the commercial model. The result of the experiment showed that after we used the linear regression models to calibrate physiological feature, the correlation coefficient reached nearly 0.9999, which is close to a perfect positive correlation. The overall evaluation results showed that the proposed method can verify and ensure the validity of the LDF prototype. Through the proposed transformation, the flux signals measured by the proposed LDF prototype can successfully be transformed to its parallel form as if it is measured by commercial LDF.

  1. Brittleness index of machinable dental materials and its relation to the marginal chipping factor.

    PubMed

    Tsitrou, Effrosyni A; Northeast, Simon E; van Noort, Richard

    2007-12-01

    The machinability of a material can be measured with the calculation of its brittleness index (BI). It is possible that different materials with different BI could produce restorations with varied marginal integrity. The degree of marginal chipping of a milled restoration can be estimated by the calculation of the marginal chipping factor (CF). The aim of this study is to investigate any possible correlation between the BI of machinable dental materials and the CF of the final restorations. The CEREC system was used to mill a wide range of materials used with that system; namely the Paradigm MZ100 (3M/ESPE), Vita Mark II (VITA), ProCAD (Ivoclar-Vivadent) and IPS e.max CAD (Ivoclar-Vivadent). A Vickers Hardness Tester was used for the calculation of BI, while for the calculation of CF the percentage of marginal chipping of crowns prepared with bevelled marginal angulations was estimated. The results of this study showed that Paradigm MZ100 had the lowest BI and CF, while IPS e.max CAD demonstrated the highest BI and CF. Vita Mark II and ProCAD had similar BI and CF and were lying between the above materials. Statistical analysis of the results showed that there is a perfect positive correlation between BI and CF for all the materials. The BI and CF could be both regarded as indicators of a material's machinability. Within the limitations of this study it was shown that as the BI increases so does the potential for marginal chipping, indicating that the BI of a material can be used as a predictor of the CF.

  2. Visibility vs. biomass in flowers: exploring corolla allocation in Mediterranean entomophilous plants.

    PubMed

    Herrera, Javier

    2009-05-01

    While pollinators may in general select for large, morphologically uniform floral phenotypes, drought stress has been proposed as a destabilizing force that may favour small flowers and/or promote floral variation within species. The general validity of this concept was checked by surveying a taxonomically diverse array of 38 insect-pollinated Mediterranean species. The interplay between fresh biomass investment, linear size and percentage corolla allocation was studied. Allometric relationships between traits were investigated by reduced major-axis regression, and qualitative correlates of floral variation explored using general linear-model MANOVA. Across species, flowers were perfectly isometrical with regard to corolla allocation (i.e. larger flowers were just scaled-up versions of smaller ones and vice versa). In contrast, linear size and biomass varied allometrically (i.e. there were shape variations, in addition to variations in size). Most floral variables correlated positively and significantly across species, except corolla allocation, which was largely determined by family membership and floral symmetry. On average, species with bilateral flowers allocated more to the corolla than those with radial flowers. Plant life-form was immaterial to all of the studied traits. Flower linear size variation was in general low among conspecifics (coefficients of variation around 10 %), whereas biomass was in general less uniform (e.g. 200-400 mg in Cistus salvifolius). Significant among-population differences were detected for all major quantitative floral traits. Flower miniaturization can allow an improved use of reproductive resources under prevailingly stressful conditions. The hypothesis that flower size reflects a compromise between pollinator attraction, water requirements and allometric constraints among floral parts is discussed.

  3. Does a minimally invasive approach affect positioning of components in unicompartmental knee arthroplasty? Early results with survivorship analysis.

    PubMed

    Cool, Steve; Victor, Jan; De Baets, Thierry

    2006-12-01

    Fifty unicompartmental knee arthroplasties (UKAs) were performed through a minimally invasive approach and were reviewed with an average follow-up of 3.7 years. This technique leads to reduced access to surgical landmarks. The purpose of this study was to evaluate whether correct component positioning is possible through this less invasive approach. Component positioning, femorotibial alignment and early outcomes were evaluated. We observed perfect tibial component position, but femoral component position was less consistent, especially in the sagittal plane. Femorotibial alignment in the coronal plane was within 2.5 degrees of the desired axis for 80% of the cases. Femoral component position in the sagittal plane was within a 10 degrees range of the ideal for 70% of the cases. The mean IKS Knee Function Score and Knee Score were 89/100 and 91/100 respectively. We observed two polyethylene dislocations, and one revision was performed for progressive patellofemoral arthrosis. According to our data, minimally invasive UKA does not conflict with component positioning although a learning curve needs to be respected, with femoral component positioning as the major obstacle.

  4. PERFECTED enhanced recovery (PERFECT-ER) care versus standard acute care for patients admitted to acute settings with hip fracture identified as experiencing confusion: study protocol for a feasibility cluster randomized controlled trial.

    PubMed

    Hammond, Simon P; Cross, Jane L; Shepstone, Lee; Backhouse, Tamara; Henderson, Catherine; Poland, Fiona; Sims, Erika; MacLullich, Alasdair; Penhale, Bridget; Howard, Robert; Lambert, Nigel; Varley, Anna; Smith, Toby O; Sahota, Opinder; Donell, Simon; Patel, Martyn; Ballard, Clive; Young, John; Knapp, Martin; Jackson, Stephen; Waring, Justin; Leavey, Nick; Howard, Gregory; Fox, Chris

    2017-12-04

    Health and social care provision for an ageing population is a global priority. Provision for those with dementia and hip fracture has specific and growing importance. Older people who break their hip are recognised as exceptionally vulnerable to experiencing confusion (including but not exclusively, dementia and/or delirium and/or cognitive impairment(s)) before, during or after acute admissions. Older people experiencing hip fracture and confusion risk serious complications, linked to delayed recovery and higher mortality post-operatively. Specific care pathways acknowledging the differences in patient presentation and care needs are proposed to improve clinical and process outcomes. This protocol describes a multi-centre, feasibility, cluster-randomised, controlled trial (CRCT) to be undertaken across ten National Health Service hospital trusts in the UK. The trial will explore the feasibility of undertaking a CRCT comparing the multicomponent PERFECTED enhanced recovery intervention (PERFECT-ER), which acknowledges the differences in care needs of confused older patients experiencing hip fracture, with standard care. The trial will also have an integrated process evaluation to explore how PERFECT-ER is implemented and interacts with the local context. The study will recruit 400 hip fracture patients identified as experiencing confusion and will also recruit "suitable informants" (individuals in regular contact with participants who will complete proxy measures). We will also recruit NHS professionals for the process evaluation. This mixed methods design will produce data to inform a definitive evaluation of the intervention via a large-scale pragmatic randomised controlled trial (RCT). The trial will provide a preliminary estimate of potential efficacy of PERFECT-ER versus standard care; assess service delivery variation, inform primary and secondary outcome selection, generate estimates of recruitment and retention rates, data collection difficulties, and completeness of outcome data and provide an indication of potential economic benefits. The process evaluation will enhance knowledge of implementation delivery and receipt. ISRCTN, 99336264 . Registered on 5 September 2016.

  5. Generation and characterization of a perfect vortex beam with a large topological charge through a digital micromirror device.

    PubMed

    Chen, Yue; Fang, Zhao-Xiang; Ren, Yu-Xuan; Gong, Lei; Lu, Rong-De

    2015-09-20

    Optical vortices are associated with a spatial phase singularity. Such a beam with a vortex is valuable in optical microscopy, hyper-entanglement, and optical levitation. In these applications, vortex beams with a perfect circle shape and a large topological charge are highly desirable. But the generation of perfect vortices with high topological charges is challenging. We present a novel method to create perfect vortex beams with large topological charges using a digital micromirror device (DMD) through binary amplitude modulation and a narrow Gaussian approximation. The DMD with binary holograms encoding both the spatial amplitude and the phase could generate fast switchable, reconfigurable optical vortex beams with significantly high quality and fidelity. With either the binary Lee hologram or the superpixel binary encoding technique, we were able to generate the corresponding hologram with high fidelity and create a perfect vortex with topological charge as large as 90. The physical properties of the perfect vortex beam produced were characterized through measurements of propagation dynamics and the focusing fields. The measurements show good consistency with the theoretical simulation. The perfect vortex beam produced satisfies high-demand utilization in optical manipulation and control, momentum transfer, quantum computing, and biophotonics.

  6. Experimental test of quantum nonlocality in three-photon Greenberger-Horne-Zeilinger entanglement

    PubMed

    Pan; Bouwmeester; Daniell; Weinfurter; Zeilinger

    2000-02-03

    Bell's theorem states that certain statistical correlations predicted by quantum physics for measurements on two-particle systems cannot be understood within a realistic picture based on local properties of each individual particle-even if the two particles are separated by large distances. Einstein, Podolsky and Rosen first recognized the fundamental significance of these quantum correlations (termed 'entanglement' by Schrodinger) and the two-particle quantum predictions have found ever-increasing experimental support. A more striking conflict between quantum mechanical and local realistic predictions (for perfect correlations) has been discovered; but experimental verification has been difficult, as it requires entanglement between at least three particles. Here we report experimental confirmation of this conflict, using our recently developed method to observe three-photon entanglement, or 'Greenberger-Horne-Zeilinger' (GHZ) states. The results of three specific experiments, involving measurements of polarization correlations between three photons, lead to predictions for a fourth experiment; quantum physical predictions are mutually contradictory with expectations based on local realism. We find the results of the fourth experiment to be in agreement with the quantum prediction and in striking conflict with local realism.

  7. Adolescent development and eating disorder related quality of life in Indian females.

    PubMed

    Lal, M; Abraham, S

    2011-03-01

    To study the relationship of adolescent development and eating disorder related quality of life in Indian females. 461 female school students (aged 12-17 yrs) were recruited from middle to high socio-economic status (SES), English speaking schools in Delhi, India. Adolescent development was measured by Tanner stage and months since menarche. Subjects completed the Quality of Life for Eating Disorders questionnaire (QOL ED), which included six subscores. Correlation and partial correlation coefficient analysis to control for Body Mass Index (BMI) were performed. After controlling for BMI, all adolescent development measures were correlated with the psychological feelings (PSY) subscore. This subscore contained items relating to confusion, social unease, sadness, difficulty coping, desiring perfection and loss of control. Tanner breast stage was correlated with the eating behaviour (EB) subscore. During adolescent development, Indian girls became more aware of their psychological feelings and emotions. Only those reporting breast development were using behaviours to control their body, weight and shape. These behaviours are not associated with the presence of disordered eating thoughts, such as preoccupation with food, eating, body weight or shape.

  8. Studies of Solar EUV Irradiance from SOHO

    NASA Technical Reports Server (NTRS)

    Floyd, Linton

    2002-01-01

    The Extreme Ultraviolet (EUV) irradiance central and first order channel time series (COC and FOC) from the Solar EUV Monitor aboard the Solar and Heliospheric observatory (SOHO) issued in early 2002 covering the time period 1/1/96-31/1201 were analyzed in terms of other solar measurements and indices. A significant solar proton effect in the first order irradiance was found and characterized. When this effect is removed, the two irradiance time series are almost perfectly correlated. Earlier studies have shown good correlation between the FOC and the Hall core-to-wing ratio and likewise, it was the strongest component of the COC. Analysis of the FOC showed dependence on the F10.7 radio flux. Analysis of the CDC signals showed additional dependences on F10.7 and the GOES x-ray fluxes. The SEM FOC was also well correlated with thein 30.4 nm channel of the SOHO EUV Imaging Telescope (EIT). The irradiance derived from all four EIT channels (30.4 nm, 17.1 nm, 28.4 nm, and 19.5 nm) showed better correlation with MgII than F10.7.

  9. Coherent perfect rotation

    NASA Astrophysics Data System (ADS)

    Crescimanno, Michael; Dawson, Nathan J.; Andrews, James H.

    2012-09-01

    Two classes of conservative, linear, optical rotary effects (optical activity and Faraday rotation) are distinguished by their behavior under time reversal. Faraday rotation, but not optical activity, is capable of coherent perfect rotation, by which we mean the complete transfer of counterpropagating coherent light fields into their orthogonal polarization. Unlike coherent perfect absorption, however, this process is explicitly energy conserving and reversible. Our study highlights the necessity of time-reversal-odd processes (not just absorption) and coherence in perfect mode conversion and thus informs the optimization of active multiport optical devices.

  10. "I want to stand on my own legs": A qualitative study of antiretroviral therapy adherence among HIV-positive women in Egypt.

    PubMed

    Badahdah, Abdallah M; Pedersen, Daphne E

    2011-06-01

    A review of the antiretroviral therapy (ART) literature revealed that not a single published study has examined the factors that influence patients' adherence to HIV medications in the Arab world. To mend this gap, this qualitative study collected data via face-to-face interviews with 27 HIV-positive Egyptian women who had been on ART for at least three months. Using a thematic analysis technique, five themes were identified: fear of stigma, financial constraints, characteristics of ART, social support, and reliance on faith. Notwithstanding the overwhelming number of inhibiting factors, most patients in this study were highly motivated to achieve perfect adherence.

  11. Key forecasts shaping nursing's perfect storm.

    PubMed

    Yoder-Wise, Patricia S

    2007-01-01

    Perfect storms abound in nursing and healthcare. How we plan for them and how we forecast effectively which ones will have tremendous impact on how we lead the profession is a challenge to anyone who is or will be a leader. This article focuses on key forecasts that contribute to creating perfect storms of the future. The "perfect storm" is a term found in multiple disciplines. The phrase denotes the condition that exists when events occur simultaneously with the result that this confluence has a greater impact than what could have resulted from a chance combination. Although perfect storms are rare, they have enormous impact when they occur, and if an alteration in any of the events occurs, the overall impact is lessened.

  12. Designing perfect linear polarization converters using perfect electric and magnetic conducting surfaces

    PubMed Central

    Zhou, Gaochao; Tao, Xudong; Shen, Ze; Zhu, Guanghao; Jin, Biaobing; Kang, Lin; Xu, Weiwei; Chen, Jian; Wu, Peiheng

    2016-01-01

    We propose a kind of general framework for the design of a perfect linear polarization converter that works in the transmission mode. Using an intuitive picture that is based on the method of bi-directional polarization mode decomposition, it is shown that when the device under consideration simultaneously possesses two complementary symmetry planes, with one being equivalent to a perfect electric conducting surface and the other being equivalent to a perfect magnetic conducting surface, linear polarization conversion can occur with an efficiency of 100% in the absence of absorptive losses. The proposed framework is validated by two design examples that operate near 10 GHz, where the numerical, experimental and analytic results are in good agreements. PMID:27958313

  13. Reflectance, illumination, and appearance in color constancy

    PubMed Central

    McCann, John J.; Parraman, Carinna; Rizzi, Alessandro

    2013-01-01

    We studied color constancy using a pair of identical 3-D Color Mondrian displays. We viewed one 3-D Mondrian in nearly uniform illumination, and the other in directional, nonuniform illumination. We used the three dimensional structures to modulate the light falling on the painted surfaces. The 3-D structures in the displays were a matching set of wooden blocks. Across Mondrian displays, each corresponding facet had the same paint on its surface. We used only 6 chromatic, and 5 achromatic paints applied to 104 block facets. The 3-D blocks add shadows and multiple reflections not found in flat Mondrians. Both 3-D Mondrians were viewed simultaneously, side-by-side. We used two techniques to measure correlation of appearance with surface reflectance. First, observers made magnitude estimates of changes in the appearances of identical reflectances. Second, an author painted a watercolor of the 3-D Mondrians. The watercolor's reflectances quantified the changes in appearances. While constancy generalizations about illumination and reflectance hold for flat Mondrians, they do not for 3-D Mondrians. A constant paint does not exhibit perfect color constancy, but rather shows significant shifts in lightness, hue and chroma in response to the structure in the nonuniform illumination. Color appearance depends on the spatial information in both the illumination and the reflectances of objects. The spatial information of the quanta catch from the array of retinal receptors generates sensations that have variable correlation with surface reflectance. Models of appearance in humans need to calculate the departures from perfect constancy measured here. This article provides a dataset of measurements of color appearances for computational models of sensation. PMID:24478738

  14. A Non-Local, Energy-Optimized Kernel: Recovering Second-Order Exchange and Beyond in Extended Systems

    NASA Astrophysics Data System (ADS)

    Bates, Jefferson; Laricchia, Savio; Ruzsinszky, Adrienn

    The Random Phase Approximation (RPA) is quickly becoming a standard method beyond semi-local Density Functional Theory that naturally incorporates weak interactions and eliminates self-interaction error. RPA is not perfect, however, and suffers from self-correlation error as well as an incorrect description of short-ranged correlation typically leading to underbinding. To improve upon RPA we introduce a short-ranged, exchange-like kernel that is one-electron self-correlation free for one and two electron systems in the high-density limit. By tuning the one free parameter in our model to recover an exact limit of the homogeneous electron gas correlation energy we obtain a non-local, energy-optimized kernel that reduces the errors of RPA for both homogeneous and inhomogeneous solids. To reduce the computational cost of the standard kernel-corrected RPA, we also implement RPA renormalized perturbation theory for extended systems, and demonstrate its capability to describe the dominant correlation effects with a low-order expansion in both metallic and non-metallic systems. Furthermore we stress that for norm-conserving implementations the accuracy of RPA and beyond RPA structural properties compared to experiment is inherently limited by the choice of pseudopotential. Current affiliation: King's College London.

  15. AN FDTD ALGORITHM WITH PERFECTLY MATCHED LAYERS FOR CONDUCTIVE MEDIA. (R825225)

    EPA Science Inventory

    We extend Berenger's perfectly matched layers (PML) to conductive media. A finite-difference-time-domain (FDTD) algorithm with PML as an absorbing boundary condition is developed for solutions of Maxwell's equations in inhomogeneous, conductive media. For a perfectly matched laye...

  16. Never Perfect Enough

    ERIC Educational Resources Information Center

    Landphair, Juliette

    2007-01-01

    What exactly is perfect? Students describe perfection as a combination of characteristics valued by their peer culture: intelligence, thin and fit physical appearance, social poise. As students chug through their daily lives--morning classes, organization meetings, club sports practice or the gym, dinner, another class, more meetings, library,…

  17. Nonreflective Conditions for Perfectly Matched Layer in Computational Aeroacoustics

    NASA Astrophysics Data System (ADS)

    Choung, Hanahchim; Jang, Seokjong; Lee, Soogab

    2018-05-01

    In computational aeroacoustics, boundary conditions such as radiation, outflow, or absorbing boundary conditions are critical issues in that they can affect the entire solution of the computation. Among these types of boundary conditions, the perfectly matched layer boundary condition, which has been widely used in computational fluid dynamics and computational aeroacoustics, is developed by augmenting the additional term in the original governing equations by an absorption function so as to stably absorb the outgoing waves. Even if the perfectly matched layer is analytically a perfectly nonreflective boundary condition, spurious waves occur at the interface, since the analysis is performed in discretized space. Hence, this study is focused on factors that affect numerical errors from perfectly matched layer to find the optimum conditions for nonreflective PML. Through a mathematical approach, a minimum width of perfectly matched layer and an optimum absorption coefficient are suggested. To validate the prediction of the analysis, numerical simulations are performed in a generalized coordinate system, as well as in a Cartesian coordinate system.

  18. A quantum Otto engine with finite heat baths: energy, correlations, and degradation

    NASA Astrophysics Data System (ADS)

    Pozas-Kerstjens, Alejandro; Brown, Eric G.; Hovhannisyan, Karen V.

    2018-04-01

    We study a driven harmonic oscillator operating an Otto cycle by strongly interacting with two thermal baths of finite size. Using the tools of Gaussian quantum mechanics, we directly simulate the dynamics of the engine as a whole, without the need to make any approximations. This allows us to understand the non-equilibrium thermodynamics of the engine not only from the perspective of the working medium, but also as it is seen from the thermal baths’ standpoint. For sufficiently large baths, our engine is capable of running a number of perfect cycles, delivering finite power while operating very close to maximal efficiency. Thereafter, having traversed the baths, the perturbations created by the interaction abruptly deteriorate the engine’s performance. We additionally study the correlations generated in the system, and, in particular, we find a direct connection between the build up of bath–bath correlations and the degradation of the engine’s performance over the course of many cycles.

  19. Griffiths phase and long-range correlations in a biologically motivated visual cortex model

    NASA Astrophysics Data System (ADS)

    Girardi-Schappo, M.; Bortolotto, G. S.; Gonsalves, J. J.; Pinto, L. T.; Tragtenberg, M. H. R.

    2016-07-01

    Activity in the brain propagates as waves of firing neurons, namely avalanches. These waves’ size and duration distributions have been experimentally shown to display a stable power-law profile, long-range correlations and 1/f b power spectrum in vivo and in vitro. We study an avalanching biologically motivated model of mammals visual cortex and find an extended critical-like region - a Griffiths phase - characterized by divergent susceptibility and zero order parameter. This phase lies close to the expected experimental value of the excitatory postsynaptic potential in the cortex suggesting that critical be-havior may be found in the visual system. Avalanches are not perfectly power-law distributed, but it is possible to collapse the distributions and define a cutoff avalanche size that diverges as the network size is increased inside the critical region. The avalanches present long-range correlations and 1/f b power spectrum, matching experiments. The phase transition is analytically determined by a mean-field approximation.

  20. Boundary Layer Transition Correlations and Aeroheating Predictions for Mars Smart Lander

    NASA Technical Reports Server (NTRS)

    Hollis, Brian R.; Liechty, Derek S.

    2002-01-01

    Laminar and turbulent perfect-gas air, Navier-Stokes computations have been performed for a proposed Mars Smart Lander entry vehicle at Mach 6 over a free stream Reynolds number range of 6.9 x 10(exp 6)/m to 2.4 x 10(exp 7)/m (2.1 x 10(exp 6)/ft to 7.3 x 10(exp 6)/ft) for angles-of-attack of 0-deg, 11-deg, 16-deg, and 20-deg, and comparisons were made to wind tunnel heating data obtained a t the same conditions. Boundary layer edge properties were extracted from the solutions and used to correlate experimental data on the effects of heat-shield penetrations (bolt-holes where the entry vehicle would be attached to the propulsion module during transit to Mars) on boundary-layer transition. A non-equilibrium Martian-atmosphere computation was performed for the peak heating point on the entry trajectory in order to determine if the penetrations would produce boundary-layer transition by using this correlation.

  1. Boundary Layer Transition Correlations and Aeroheating Predictions for Mars Smart Lander

    NASA Technical Reports Server (NTRS)

    Hollis, Brian R.; Liechty, Derek S.

    2002-01-01

    Laminar and turbulent perfect-gas air, Navier-Stokes computations have been performed for a proposed Mars Smart Lander entry vehicle at Mach 6 over a free stream Reynolds number range of 6.9 x 10(exp 6/m to 2.4 x 10(exp 7)m(2.1 x 10(exp 6)/ft to 7.3 x 10(exp 6)ft) for angles-of-attack of 0-deg, 11-deg, 16-deg, and 20-deg, and comparisons were made to wind tunnel heating data obtained at the same conditions. Boundary layer edge properties were extracted from the solutions and used to correlate experimental data on the effects of heat-shield penetrations (bolt-holes where the entry vehicle would be attached to the propulsion module during transit to Mars) on boundary-layer transition. A non-equilibrium Martian-atmosphere computation was performed for the peak heating point on the entry trajectory in order to determine if the penetrations would produce boundary-layer transition by using this correlation.

  2. Charged particle layers in the Debye limit.

    PubMed

    Golden, Kenneth I; Kalman, Gabor J; Kyrkos, Stamatios

    2002-09-01

    We develop an equivalent of the Debye-Hückel weakly coupled equilibrium theory for layered classical charged particle systems composed of one single charged species. We consider the two most important configurations, the charged particle bilayer and the infinite superlattice. The approach is based on the link provided by the classical fluctuation-dissipation theorem between the random-phase approximation response functions and the Debye equilibrium pair correlation function. Layer-layer pair correlation functions, screened and polarization potentials, static structure functions, and static response functions are calculated. The importance of the perfect screening and compressibility sum rules in determining the overall behavior of the system, especially in the r--> infinity limit, is emphasized. The similarities and differences between the quasi-two-dimensional bilayer and the quasi-three-dimensional superlattice are highlighted. An unexpected behavior that emerges from the analysis is that the screened potential, the correlations, and the screening charges carried by the individual layers exhibit a marked nonmonotonic dependence on the layer separation.

  3. Interobserver Reliability of the Total Body Score System for Quantifying Human Decomposition.

    PubMed

    Dabbs, Gretchen R; Connor, Melissa; Bytheway, Joan A

    2016-03-01

    Several authors have tested the accuracy of the Total Body Score (TBS) method for quantifying decomposition, but none have examined the reliability of the method as a scoring system by testing interobserver error rates. Sixteen participants used the TBS system to score 59 observation packets including photographs and written descriptions of 13 human cadavers in different stages of decomposition (postmortem interval: 2-186 days). Data analysis used a two-way random model intraclass correlation in SPSS (v. 17.0). The TBS method showed "almost perfect" agreement between observers, with average absolute correlation coefficients of 0.990 and average consistency correlation coefficients of 0.991. While the TBS method may have sources of error, scoring reliability is not one of them. Individual component scores were examined, and the influences of education and experience levels were investigated. Overall, the trunk component scores were the least concordant. Suggestions are made to improve the reliability of the TBS method. © 2016 American Academy of Forensic Sciences.

  4. 12 CFR 1511.3 - Law governing other interests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1511.3 Banks and Banking DEPARTMENT OF THE TREASURY RESOLUTION FUNDING CORPORATION BOOK-ENTRY PROCEDURE... perfection, effect of perfection or non-perfection and priority of a security interest in a Security... Securities Account is a clearing corporation, and the Participant's interest in a Book-entry Funding...

  5. 12 CFR 1511.3 - Law governing other interests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1511.3 Banks and Banking DEPARTMENT OF THE TREASURY RESOLUTION FUNDING CORPORATION BOOK-ENTRY PROCEDURE... perfection, effect of perfection or non-perfection and priority of a security interest in a Security... Securities Account is a clearing corporation, and the Participant's interest in a Book-entry Funding...

  6. On universal procrastination

    NASA Astrophysics Data System (ADS)

    Eliazar, Iddo

    2017-09-01

    This paper presents a general stochastic model for procrastination with respect to a deadline. The model establishes a universal procrastination pattern that follows an inverse power-law: if the time remaining to the deadline is r then the response is 1/rε , where ɛ is a positive exponent. The model further establishes that the exponent value ε =1 , which yields the harmonic response 1/r , stands out as special and distinguishable. The theoretical results of the model are shown to be in perfect accord with recent empirical findings.

  7. Heat-treated (in single aliquot or batch) colostrum outperforms non-heat-treated colostrum in terms of quality and transfer of immunoglobulin G in neonatal Jersey calves.

    PubMed

    Kryzer, A A; Godden, S M; Schell, R

    2015-03-01

    The objective of this randomized clinical trial was to describe the effect on colostrum characteristics and passive transfer of IgG in neonatal calves when using the Perfect Udder colostrum management system (single-aliquot treatment; Dairy Tech Inc., Greeley, CO) compared with a negative control (fresh refrigerated or fresh frozen colostrum) and a positive control (batch heat-treated colostrum). First-milking Jersey colostrum was pooled to achieve 31 unique batches with a minimum of 22.8 L per batch. The batch was then divided into 4 with 3.8 L allocated to each treatment group: (1) heat-treated in Perfect Udder bag at 60°C for 60 min and then stored at -20°C (PU); (2) heat-treated in a batch pasteurizer (Dairy Tech Inc.) at 60°C for 60 min and then stored at -20°C in Perfect Udder bag (DTB; positive control); (3) fresh frozen colostrum stored at -20°C in Perfect Udder bag (FF; negative control); and (4) fresh refrigerated colostrum stored at 4°C in Perfect Udder bag (FR; negative control). Colostrum from all treatments was sampled for analysis of IgG concentration and bacterial culture immediately after batch assembly, after processing, and before feeding. Newborn Jersey calves were randomly assigned to be fed 3.8 L of colostrum from 1 of the 4 treatment groups. A prefeeding, 0-h blood sample was collected, calves were fed by esophageal tube within 2 h of birth, and then a 24-h postfeeding blood sample was collected. Paired serum samples from 0- and 24-h blood samples were analyzed for IgG concentration (mg/mL) using radial immunodiffusion analysis. The overall mean IgG concentration in colostrum was 77.9 g/L and was not affected by treatment. Prefeeding total plate counts (log10 cfu/mL) were significantly different for all 4 treatments and were lower for heat-treated colostrum (PU=4.23, DTB=3.63) compared with fresh colostrum (FF=5.68, FR=6.53). Total coliform counts (log10 cfu/mL) were also significantly different for all 4 treatments and were lower for heat-treated colostrum (PU=0.45, DTB=1.08) compared with fresh colostrum (FF=3.82, FR=4.80). Mean 24-h serum IgG concentrations were significantly higher for calves in the PU (41.0 mg/mL) and DTB (40.6 mg/mL) groups compared with FF (35.1 mg/mL) and FR (35.5 mg/mL) groups. Mean apparent efficiency of absorption of IgG was significantly higher for the PU (37%) and DTB (37%) groups compared with the FF (32%) and FR (32%) groups. Calves fed heat-treated colostrum (PU or DTB) experienced significantly improved AEA and serum IgG concentrations. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  8. Time domain passivity controller for 4-channel time-delay bilateral teleoperation.

    PubMed

    Rebelo, Joao; Schiele, Andre

    2015-01-01

    This paper presents an extension of the time-domain passivity control approach to a four-channel bilateral controller under the effects of time delays. Time-domain passivity control has been used successfully to stabilize teleoperation systems with position-force and position-position controllers; however, the performance with such control architectures is sub-optimal both with and without time delays. This work extends the network representation of the time-domain passivity controller to the four-channel architecture, which provides perfect transparency to the user without time delay. The proposed architecture is based on modelling the controllers as dependent voltage sources and using only series passivity controllers. The obtained results are shown on a one degree-of-freedom setup and illustrate the stabilization behaviour of the proposed controller when time delay is present in the communication channel.

  9. Evaluating Antarctic sea ice predictability at seasonal to interannual timescales in global climate models

    NASA Astrophysics Data System (ADS)

    Marchi, Sylvain; Fichefet, Thierry; Goosse, Hugues; Zunz, Violette; Tietsche, Steffen; Day, Jonny; Hawkins, Ed

    2016-04-01

    Unlike the rapid sea ice losses reported in the Arctic, satellite observations show an overall increase in Antarctic sea ice extent over recent decades. Although many processes have already been suggested to explain this positive trend, it remains the subject of current investigations. Understanding the evolution of the Antarctic sea ice turns out to be more complicated than for the Arctic for two reasons: the lack of observations and the well-known biases of climate models in the Southern Ocean. Irrespective of those issues, another one is to determine whether the positive trend in sea ice extent would have been predictable if adequate observations and models were available some decades ago. This study of Antarctic sea ice predictability is carried out using 6 global climate models (HadGEM1.2, MPI-ESM-LR, GFDL CM3, EC-Earth V2, MIROC 5.2 and ECHAM 6-FESOM) which are all part of the APPOSITE project. These models are used to perform hindcast simulations in a perfect model approach. The predictive skill is estimated thanks to the PPP (Potential Prognostic Predictability) and the ACC (Anomaly Correlation Coefficient). The former is a measure of the uncertainty of the ensemble while the latter assesses the accuracy of the prediction. These two indicators are applied to different variables related to sea ice, in particular the total sea ice extent and the ice edge location. This first model intercomparison study about sea ice predictability in the Southern Ocean aims at giving a general overview of Antarctic sea ice predictability in current global climate models.

  10. 10 CFR 611.108 - Perfection of liens and preservation of collateral.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Perfection of liens and preservation of collateral. 611.108 Section 611.108 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Direct Loan Program § 611.108 Perfection of liens and preservation...

  11. 10 CFR 609.16 - Perfection of liens and preservation of collateral.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Perfection of liens and preservation of collateral. 609.16 Section 609.16 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS LOAN GUARANTEES FOR PROJECTS THAT EMPLOY INNOVATIVE TECHNOLOGIES § 609.16 Perfection of liens and preservation of collateral. (a...

  12. Structure and symmetry in coherent perfect polarization rotation

    NASA Astrophysics Data System (ADS)

    Crescimanno, Michael; Zhou, Chuanhong; Andrews, James H.; Baker, Michael A.

    2015-01-01

    Theoretical investigations of different routes to coherent perfect polarization rotation illustrate its phenomenological connection with coherent perfect absorption. Our study of systems with broken parity, layering, combined Faraday rotation and optical activity, or a rotator-loaded optical cavity highlights their similarity and suggests alternate approaches to improving and miniaturizing optical devices.

  13. Coherent Perfect Rotation

    NASA Astrophysics Data System (ADS)

    Crescimanno, Michael; Dawson, Nathan; Andrews, James

    2012-04-01

    Two classes of conservative, linear, optical rotary effects (optical activity and Faraday rotation) are distinguished by their behavior under time reversal. In analogy with coherent perfect absorption, where counterpropagating light fields are controllably converted into other degrees of freedom, we show that in a linear-conservative medium only time-odd (Faraday) rotation is capable of coherent perfect rotation, by which we mean the complete transfer of counterpropagating coherent light fields into their orthogonal polarization. This highlights the necessity of time reversal odd processes (not just absorption) and coherence in perfect mode conversion and may inform device design.

  14. Enhancing intensity and refractive index sensing capability with infrared plasmonic perfect absorbers.

    PubMed

    Cheng, Fei; Yang, Xiaodong; Gao, Jie

    2014-06-01

    An infrared refractive index sensor based on plasmonic perfect absorbers for glucose concentration sensing is experimentally demonstrated. Utilizing substantial absorption contrast between a perfect absorber (∼98% at normal incidence) and a non-perfect absorber upon the refractive index change, a maximum value of figure of merit (FOM*) about 55 and a bulk wavelength sensitivity about 590  nm/RIU are achieved. The demonstrated sensing platform provides great potential in improving the performance of plasmonic refractive index sensors and developing future surface enhanced infrared spectroscopy.

  15. Zeroth order Fabry-Perot resonance enabled ultra-thin perfect light absorber using percolation aluminum and silicon nanofilms

    DOE PAGES

    Mirshafieyan, Seyed Sadreddin; Luk, Ting S.; Guo, Junpeng

    2016-03-04

    Here, we demonstrated perfect light absorption in optical nanocavities made of ultra-thin percolation aluminum and silicon films deposited on an aluminum surface. The total layer thickness of the aluminum and silicon films is one order of magnitude less than perfect absorption wavelength in the visible spectral range. The ratio of silicon cavity layer thickness to perfect absorption wavelength decreases as wavelength decreases due to the increased phase delays at silicon-aluminum boundaries at shorter wavelengths. It is explained that perfect light absorption is due to critical coupling of incident wave to the fundamental Fabry-Perot resonance mode of the structure where themore » round trip phase delay is zero. Simulations were performed and the results agree well with the measurement results.« less

  16. A proposal of a perfect graphene absorber with enhanced design and fabrication tolerance.

    PubMed

    Lee, Sangjun; Tran, Thang Q; Heo, Hyungjun; Kim, Myunghwan; Kim, Sangin

    2017-07-06

    We propose a novel device structure for the perfect absorption of a one-sided lightwavve illumination, which consists of a high-contrast grating (HCG) and an evanescently coupled slab with an absorbing medium (graphene). The operation principle and design process of the proposed structure are analyzed using the coupled mode theory (CMT), which is confirmed by the rigorous coupled wave analysis (RCWA). According to the CMT analysis, in the design of the proposed perfect absorber, the HCG, functioning as a broadband reflector, and the lossy slab structure can be optimized separately. In addition, we have more design parameters than conditions to satisfy; that is, we have more than enough degrees of freedom in the device design. This significantly relieves the complexity of the perfect absorber design. Moreover, in the proposed perfect absorber, most of the incident wave is confined in the slab region with strong field enhancement, so that the absorption performance is very tolerant to the variation of the design parameters near the optimal values for the perfect absorption. It has been demonstrated numerically that absorption spectrum tuning over a wider wavelength range of ~300 nm is possible, keeping significantly high maximum absorption (>95%). It is also shown that the proposed perfect absorber outperforms the previously proposed scheme in all aspects.

  17. Tunable dual-band nearly perfect absorption based on a compound metallic grating

    NASA Astrophysics Data System (ADS)

    Gao, Hua; Zheng, Zhi-Yuan; Feng, Juan

    2017-02-01

    Traditional metallic gratings and novel metamaterials are two basic kinds of candidates for perfect absorption. Comparatively speaking, metallic grating is the preferred choice for the same absorption effect because it is structurally simpler and more convenient to fabricate. However, to date, most of the perfect absorption effects achieved based on metamaterials are also available using an metallic grating except the tunable dual(multi)-band perfect absorption. To fill this gap, in this paper, by adding subgrooves on the rear surface as well as inside the grating slits to a free-standing metallic grating, tunable dual-band perfect absorption is also obtained for the first time. The grooves inside the slits is to tune the frequency of the Cavity Mode(CM) resonance which enhances the transmission and suppresses the reflectance simultaneously. The grooves on the rear surface give rise to the phase resonance which not only suppresses the transmission but also reinforces the reflectance depression effect. Thus, when the phase resonance and the frequency tunable CM resonance occur together, transmission and reflection can be suppressed simultaneously, dual-band nearly perfect absorption with tunable frequencies is obtained. To our knowledge, this perfect absorption phenomenon is achieved for the first time in a designed metallic grating structure.

  18. A direct correlation among indoor Rn, soil gas Rn and geology in the Reading Prong near Boyertown, Pennsylvania

    USGS Publications Warehouse

    Reimer, G.M.; Gundersen, L.C.S.

    1989-01-01

    We feel that this study suggests a relationship among geology, soil gas Rn and the potential for indoor Rn accumulation in this portion of the Reading Prong. There are deviations from a perfect correlation but these are related to inhomogeneities in the geologic environment and perhaps variations in construction techniques of homes in the area. This study also demonstrates that several analyses in a small area may be necessary to adequately determine the Rn distribution for a particular geologic unit. That scale would be determined by the complexity of the local geology. Where no discrete source of elevated Rn supply is found for dwellings having a significant Rn accumulation, the implication is that overall gross permeability may be sufficient to supply Rn from a larger volume of soil and rock.

  19. Correlative fractography: combining scanning electron microscopy and light microscopes for qualitative and quantitative analysis of fracture surfaces.

    PubMed

    Hein, Luis Rogerio de Oliveira; de Oliveira, José Alberto; de Campos, Kamila Amato

    2013-04-01

    Correlative fractography is a new expression proposed here to describe a new method for the association between scanning electron microscopy (SEM) and light microscopy (LM) for the qualitative and quantitative analysis of fracture surfaces. This article presents a new method involving the fusion of one elevation map obtained by extended depth from focus reconstruction from LM with exactly the same area by SEM and associated techniques, as X-ray mapping. The true topographic information is perfectly associated to local fracture mechanisms with this new technique, presented here as an alternative to stereo-pair reconstruction for the investigation of fractured components. The great advantage of this technique resides in the possibility of combining any imaging methods associated with LM and SEM for the same observed field from fracture surface.

  20. Intra- and interobserver agreement for fetal cerebral measurements in 3D-ultrasonography.

    PubMed

    Albers, Maria E W A; Buisman, Erato T I A; Kahn, René S; Franx, Arie; Onland-Moret, N Charlotte; de Heus, Roel

    2018-04-10

    The aim of this study is to evaluate intra- and interobserver agreement for measurement of intracranial, cerebellar, and thalamic volume with the Virtual Organ Computer-aided AnaLysis (VOCAL) technique in three-dimensional ultrasound images, in comparison to two-dimensional measurements of these brain structures. Three-dimensional ultrasound images of the brains of 80 fetuses at 20-24 weeks' gestational age were obtained from YOUth, a Dutch prospective cohort study. Two observers performed offline measurement of the occipitofrontal diameter, intracranial volume, transcerebellar diameter, cerebellar volume, and thalamic width, area, and volume, independently. VOCAL was used for calculation of the volumes. The two-way random, single measures intraclass correlation coefficient (ICC) was used for analysis of agreement and Bland-Altman plots were configured. Intra- and interobserver agreement was almost perfect for occipitofrontal diameter (intra ICC 0.88, 95% CI 0.82-0.92; inter ICC 0.91, 95% CI 0.85-0.94), intracranial volume (intra ICC 0.96, 95% CI 0.91-0.98; inter ICC 0.97, 95% CI 0.96-0.98) and transcerebellar diameter (intra ICC 0.91, 95% CI 0.86-0.94; inter ICC 0.86, 95% CI 0.78-0.910). For cerebellar volume, the intraobserver agreement was almost perfect (0.85, 95% CI 0.76-0.90), whereas the interobserver agreement was substantial (0.75, 95% CI 0.44-0.88). Agreement was only moderate for thalamic measurements. Bland-Altman plots for the volume measurements are normally distributed with acceptable mean differences and 95% limits of agreement. The intra- and interobserver agreement of the measurement of intracranial and cerebellar volume with VOCAL was almost perfect. These measurements are therefore reliable, and can be used to investigate fetal brain development. Thalamic measurements are not reliable enough. © 2018 Wiley Periodicals, Inc.

  1. Links between Evolution, Development, Human Anatomy, Pathology, and Medicine, with A Proposition of A Re-defined Anatomical Position and Notes on Constraints and Morphological "Imperfections".

    PubMed

    Diogo, Rui; Molnar, Julia

    2016-06-01

    Surprisingly the oldest formal discipline in medicine (anatomy) has not yet felt the full impact of evolutionary developmental biology. In medical anatomy courses and textbooks, the human body is still too often described as though it is a "perfect machine." In fact, the study of human anatomy predates evolutionary theory; therefore, many of its conventions continue to be outdated, making it difficult to study, understand, and treat the human body, and to compare it with that of other, nonbipedal animals, including other primates. Moreover, such an erroneous view of our anatomy as "perfect" can be used to fuel nonevolutionary ideologies such as intelligent design. In the section An Evolutionary and Developmental Approach to Human Anatomical Position of this paper, we propose the redefinition of the "human standard anatomical position" used in textbooks to be consistent with human evolutionary and developmental history. This redefined position also simplifies, for students and practitioners of the health professions, the study and learning of embryonic muscle groups (each group including muscles derived from the same/ontogenetically closely related primordium/primordia) and joint movements and highlights the topological correspondence between the upper and lower limbs. Section Evolutionary and Developmental Constraints, "Imperfections" and Sports Pathologies continues the theme by describing examples of apparently "illogical" characteristics of the human body that only make sense when one understands the developmental and evolutionary constraints that have accumulated over millions of years. We focus, in particular, on musculoskeletal functional problems and sports pathologies to emphasize the links with pathology and medicine. These examples demonstrate how incorporating evolutionary theory into anatomy education can be helpful for medical students, teachers, researchers, and physicians, as well as for anatomists, functional morphologists, and evolutionary and developmental biologists. © 2016 Wiley Periodicals, Inc.

  2. Correlations of charge neutrality level with electronic structure and p-d hybridization

    PubMed Central

    Das, Arkaprava; Gautam, Subodh K.; Shukla, D. K.; Singh, Fouran

    2017-01-01

    The formation of charge neutrality level (CNL) in highly conducting Cadmium oxide (CdO) thin films is demonstarted by the observed variation in the band gap upon annealing and doping. It may be explained by the observation that Tin (Sn) doping breaks the perfect periodicity of CdO cubic crystal structure and creates virtual gap states (ViGS). The level of local CNL resides at the branch point of ViGS, making the energy at which native defect’s character changes from predominantly donor-like below CNL to predominantly acceptor-like above the CNL and a schematic band diagram is developed to substantiate the same. Further investigations using soft x-ray absorption spectroscopy (SXAS) at Oxygen and Cadmium edges show the reduction of Sn4+ to Sn2+. The analysis of the spectral features has revealed an evidence of p-d interaction between O 2p and Cd 4d orbitals that pushes the valence band minima at higher energies which is symmetry forbidden at г point and causing a positive valance band dispersion away from the zone centre in the г ~ L, K direction. Thus, origin of the CNL is attributed to the high density of the Oxygen vacancies as confirmed by the change in the local electronic structure and p-d hybridization of orbitals. PMID:28102312

  3. Dual of the Janus solution: An interface conformal field theory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Clark, A.B.; Karch, A.; Freedman, D.Z.

    2005-03-15

    We propose and study a specific gauge theory dual of the smooth, nonsupersymmetric (and apparently stable) Janus solution of Type IIB supergravity found in Bak et al. [J. High Energy Phys. 05 (2003) 072]. The dual field theory is N=4 SYM theory on two half-spaces separated by a planar interface with different coupling constants in each half-space. We assume that the position dependent coupling multiplies the operator L{sup '} which is the fourth descendent of the primary TrX{sup {l_brace}}{sup I}X{sup J{r_brace}} and closely related to the N=4 Lagrangian density. At the classical level supersymmetry is broken explicitly, but SO(3,2) conformalmore » symmetry is preserved. We use conformal perturbation theory to study various correlation functions to first and second order in the discontinuity of g{sub YM}{sup 2}, confirming quantum level conformal symmetry. Certain quantities such as the vacuum expectation value are protected to all orders in g{sub YM}{sup 2}N, and we find perfect agreement between the weak coupling value in the gauge theory and the strong coupling gravity result. SO(3,2) symmetry requires vanishing vacuum energy, =0, and this is confirmed in first order in the discontinuity.« less

  4. Correlations of charge neutrality level with electronic structure and p-d hybridization

    NASA Astrophysics Data System (ADS)

    Das, Arkaprava; Gautam, Subodh K.; Shukla, D. K.; Singh, Fouran

    2017-01-01

    The formation of charge neutrality level (CNL) in highly conducting Cadmium oxide (CdO) thin films is demonstarted by the observed variation in the band gap upon annealing and doping. It may be explained by the observation that Tin (Sn) doping breaks the perfect periodicity of CdO cubic crystal structure and creates virtual gap states (ViGS). The level of local CNL resides at the branch point of ViGS, making the energy at which native defect’s character changes from predominantly donor-like below CNL to predominantly acceptor-like above the CNL and a schematic band diagram is developed to substantiate the same. Further investigations using soft x-ray absorption spectroscopy (SXAS) at Oxygen and Cadmium edges show the reduction of Sn4+ to Sn2+. The analysis of the spectral features has revealed an evidence of p-d interaction between O 2p and Cd 4d orbitals that pushes the valence band minima at higher energies which is symmetry forbidden at г point and causing a positive valance band dispersion away from the zone centre in the г ~ L, K direction. Thus, origin of the CNL is attributed to the high density of the Oxygen vacancies as confirmed by the change in the local electronic structure and p-d hybridization of orbitals.

  5. Selective attention in an insect visual neuron.

    PubMed

    Wiederman, Steven D; O'Carroll, David C

    2013-01-21

    Animals need attention to focus on one target amid alternative distracters. Dragonflies, for example, capture flies in swarms comprising prey and conspecifics, a feat that requires neurons to select one moving target from competing alternatives. Diverse evidence, from functional imaging and physiology to psychophysics, highlights the importance of such "competitive selection" in attention for vertebrates. Analogous mechanisms have been proposed in artificial intelligence and even in invertebrates, yet direct neural correlates of attention are scarce from all animal groups. Here, we demonstrate responses from an identified dragonfly visual neuron that perfectly match a model for competitive selection within limits of neuronal variability (r(2) = 0.83). Responses to individual targets moving at different locations within the receptive field differ in both magnitude and time course. However, responses to two simultaneous targets exclusively track those for one target alone rather than any combination of the pair. Irrespective of target size, contrast, or separation, this neuron selects one target from the pair and perfectly preserves the response, regardless of whether the "winner" is the stronger stimulus if presented alone. This neuron is amenable to electrophysiological recordings, providing neuroscientists with a new model system for studying selective attention. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Image processing analysis of geospatial uav orthophotos for palm oil plantation monitoring

    NASA Astrophysics Data System (ADS)

    Fahmi, F.; Trianda, D.; Andayani, U.; Siregar, B.

    2018-03-01

    Unmanned Aerial Vehicle (UAV) is one of the tools that can be used to monitor palm oil plantation remotely. With the geospatial orthophotos, it is possible to identify which part of the plantation land is fertile for planted crops, means to grow perfectly. It is also possible furthermore to identify less fertile in terms of growth but not perfect, and also part of plantation field that is not growing at all. This information can be easily known quickly with the use of UAV photos. In this study, we utilized image processing algorithm to process the orthophotos for more accurate and faster analysis. The resulting orthophotos image were processed using Matlab including classification of fertile, infertile, and dead palm oil plants by using Gray Level Co-Occurrence Matrix (GLCM) method. The GLCM method was developed based on four direction parameters with specific degrees 0°, 45°, 90°, and 135°. From the results of research conducted with 30 image samples, it was found that the accuracy of the system can be reached by using the features extracted from the matrix as parameters Contras, Correlation, Energy, and Homogeneity.

  7. Effect of the purity of starting materials on the growth and properties of potassium dihydrogen phosphate single crystals – A comparative study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rajesh, P., E-mail: rajeshp@ssn.edu.in; Charoen In, Urit; Manyum, Prapun

    2014-11-15

    Highlights: • Bulk size KDP crystal has been grown with higher growth rate. • Systematic study on the effect of starting materials has been done. • Crystalline perfection is maintained in the entire crystal. - Abstract: A systematic study on the effect of purity of starting materials on the growth and properties of potassium dihydrogen phosphate single crystals is crucial for the future study of the material for nonlinear optical applications. Potassium dihydrogen phosphate crystals were grown using high pure (99.999%) and ordinary (99.9%) starting raw materials using slow cooling method in identical conditions. Their optical transparency and crystalline perfectionmore » are studied by UV and high resolution X-ray diffraction analyses respectively. The results are checked with the help of etching analyses. The full width at half maximum is 8″ which is close to that expected from the plane wave theory of dynamical X-ray diffraction for an ideally perfect crystal. Results of those studies are correlated with each other. The quantitative results show that the raw material plays an important role in the growth of good quality crystals.« less

  8. Bimodal distribution of performance in discriminating major/minor modes.

    PubMed

    Chubb, Charles; Dickson, Christopher A; Dean, Tyler; Fagan, Christopher; Mann, Daniel S; Wright, Charles E; Guan, Maime; Silva, Andrew E; Gregersen, Peter K; Kowalsky, Elena

    2013-10-01

    This study investigated the abilities of listeners to classify various sorts of musical stimuli as major vs minor. All stimuli combined four pure tones: low and high tonics (G5 and G6), dominant (D), and either a major third (B) or a minor third (B[symbol: see text]). Especially interesting results were obtained using tone-scrambles, randomly ordered sequences of pure tones presented at ≈15 per second. All tone-scrambles tested comprised 16 G's (G5's + G6's), 8 D's, and either 8 B's or 8 B[symbol: see text]'s. The distribution of proportion correct across 275 listeners tested over the course of three experiments was strikingly bimodal, with one mode very close to chance performance, and the other very close to perfect performance. Testing with tone-scrambles thus sorts listeners fairly cleanly into two subpopulations. Listeners in subpopulation 1 are sufficiently sensitive to major vs minor to classify tone-scrambles nearly perfectly; listeners in subpopulation 2 (comprising roughly 70% of the population) have very little sensitivity to major vs minor. Skill in classifying major vs minor tone-scrambles shows a modest correlation of around 0.5 with years of musical training.

  9. Intravenous fluid temperature management by infrared thermometer.

    PubMed

    Lapostolle, Frédéric; Catineau, Jean; Le Toumelin, Philippe; Proust, Clément; Garrigue, Bruno; Galinski, Michel; Adnet, Frédéric

    2006-03-01

    The management of intravenous (IV) fluid temperature is a daily challenge in critical care, anesthesiology, and emergency medicine. Infusion of IV fluids at the right temperature partly influences clinical outcomes of critically ill patients. Nowadays, intravenous fluid temperature is poorly managed, as no suitable device is routinely available. Infrared (IR) thermometers have been recently developed for industrial, personal, or medical purposes. The aim of this study was to evaluate the accuracy of an IR thermometer in measuring temperature of warmed and cooled infusion fluids in fluid bags. This study compared temperatures simultaneously recorded by an infrared thermometer and a temperature sensor. Temperatures of warmed (41 degrees C) and cooled (4 degrees C) infusion fluids in fluid bags were recorded by 2 independent operators every minute until IV bags' temperature reached ambient temperature. The relation curve was established with 576 measures. Temperature measures performed with an IR thermometer were perfectly linear and perfectly correlated with the reference method (R(2) = 0.995, P < 10(-5)). Infrared thermometers are efficient to measure IV fluid bag temperature in the range of temperatures used in clinical practice. As these devices are easy to use and inexpensive, they could be largely used in critical care, anesthesiology, or emergency medicine.

  10. Determination of the mental foramen position in dental radiographs in 18-30 year olds.

    PubMed

    Currie, Charlotte C; Meechan, John G; Whitworth, John M; Carr, Andrew; Corbett, Ian P

    2016-01-01

    To determine the radiographic position and reliability of assessing mental foramen (MF) position in relation to premolar crowns in an 18- to 30-year-old UK-based population. Following ethical approval and a power calculation, the position of the MF was recorded in relation to premolar crowns and apices in 100 dental panoramic tomographs. Positions were assessed by three senior clinicians independently, then by consensus. Data were analysed using descriptive statistics, χ(2) and Fleiss' and Cohen's kappa. Reliability data showed only fair to moderate agreement on independent scoring. Substantial to almost perfect agreement was achieved by consensus, demonstrating the most common position for the MF to be between the first and second premolar teeth when using both premolar crowns (51%) and apices (76%) as reference points. There was a significant difference in the position of the foramen between the left and right sides (p < 0.05), with only 62% of cases showing symmetry. The most common position for the MF is between the first and second premolar teeth; however, anatomical variation is seen. Use of pre-operative radiographs to relate the position of the MF to premolar crowns may not be reliable.

  11. Measurements of observables replaced by “evaluations” in Quantum Theory

    NASA Astrophysics Data System (ADS)

    Nisticò, Giuseppe; Sestito, Angela

    2015-07-01

    In quantum physics there are circumstances where the direct measurement of particular observables encounters difficulties; in some of these cases, however, its value can be evaluated, i.e. it can be inferred by measuring another observable characterized by perfect correlation with the observable of interest. Though an evaluation is often interpreted as a measurement of the evaluated observable, we prove that the two concepts cannot be identified in quantum physics, because the identification yields contradictions. Then, we establish the conceptual status of evaluations in Quantum Theory and the role can be ascribed to them.

  12. Stacking fault induced tunnel barrier in platelet graphite nanofiber

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lan, Yann-Wen, E-mail: chiidong@phys.sinica.edu.tw, E-mail: ywlan@phys.sinica.edu.tw; Chang, Yuan-Chih; Chang, Chia-Seng

    A correlation study using image inspection and electrical characterization of platelet graphite nanofiber devices is conducted. Close transmission electron microscopy and diffraction pattern inspection reveal layers with inflection angles appearing in otherwise perfectly stacked graphene platelets, separating nanofibers into two domains. Electrical measurement gives a stability diagram consisting of alternating small-large Coulomb blockade diamonds, suggesting that there are two charging islands coupled together through a tunnel junction. Based on these two findings, we propose that a stacking fault can behave as a tunnel barrier for conducting electrons and is responsible for the observed double-island single electron transistor characteristics.

  13. Thermal emergence of laser-induced spin dynamics for a Ni4 cluster

    NASA Astrophysics Data System (ADS)

    Sold, S.; Lefkidis, G.; Kamble, B.; Berakdar, J.; Hübner, W.

    2018-05-01

    We investigate the thermodynamic behavior of laser-induced spin dynamics of a perfect and a distorted Ni4 square in combination with an external thermal bath, by using the Lindblad-superoperator formalism. The energies of the planar molecules are determined with highly correlated ab initio quantum-chemistry calculations. When the distorted structure couples to the thermal bath a unique spin dynamics, i.e., a spin flip, emerges, due to the interplay of optically and thermally induced electronic transitions. The charge and spin relaxation times in dependence on the coupling strength and the bath temperature are determined and compared.

  14. Deterministic and efficient quantum cryptography based on Bell's theorem

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen Zengbing; Pan Jianwei; Physikalisches Institut, Universitaet Heidelberg, Philosophenweg 12, 69120 Heidelberg

    2006-05-15

    We propose a double-entanglement-based quantum cryptography protocol that is both efficient and deterministic. The proposal uses photon pairs with entanglement both in polarization and in time degrees of freedom; each measurement in which both of the two communicating parties register a photon can establish one and only one perfect correlation, and thus deterministically create a key bit. Eavesdropping can be detected by violation of local realism. A variation of the protocol shows a higher security, similar to the six-state protocol, under individual attacks. Our scheme allows a robust implementation under the current technology.

  15. De Sitter universe described by a binary mixture with a variable cosmological constant λ

    NASA Astrophysics Data System (ADS)

    Biswal, S. K.

    2018-04-01

    We have constructed a self-consistent system of Bianchi Type VI0 cosmology, and mingling of perfect fluid and dark energy in five dimensions. The usual equation of state p = γ ρ with γ \\in [0, 1] is chosen by the perfect fluid. The dark energy assumed to be chosen is taken into consideration to be either the quintessence or Chaplygin gas. The same solutions pertaining to the corresponding the field equations of Einstein are obtained as a quadrature. State parameter's equations for dark energy ω is found to be consistent enough with the recent observations of SNe Ia data (SNe Ia data with CMBR anisotropy) and galaxy clustering statistics. Here our models predict that the rate of expansion of Universe would increase with passage of time. The cosmological constant Λ is traced as a declining function of time and it gets nearer to a small positive value later on which is supported by the results from the current supernovae Ia observations. Also a detail discussion is made on the physical and geometrical aspects of the models.

  16. Processing Elided Verb Phrases with Flawed Antecedents: the Recycling Hypothesis

    PubMed Central

    Arregui, Ana; Clifton, Charles; Frazier, Lyn; Moulton, Keir

    2006-01-01

    Traditional syntactic accounts of verb phrase ellipsis (e.g. “Jason laughed. Sam did [ ] too.”) categorize as ungrammatical many sentences that language users find acceptable (they “undergenerate”); semantic accounts overgenerate. We propose that a processing theory, together with a syntactic account, does a better job of describing and explaining the data on verb phrase-ellipsis. Five acceptability judgment experiments supported a “VP recycling hypothesis,” which claims that when a syntactically-matching antecedent is not available, the listener/reader creates one using the materials at hand. Experiments 1 and 2 used verb phrase ellipsis sentences with antecedents ranging from perfect (a verb phrase in matrix verb phrase position) to impossible (a verb phrase containing only a deverbal word). Experiments 3 and 4 contrasted antecedents in verbal versus nominal gerund subjects. Experiment 5 explored the possibility that speakers are particularly likely to go beyond the grammar and produce elided constituents without perfect matching antecedents when the antecedent needed is less marked than the antecedent actually produced. This experiment contrasted active (unmarked) and passive antecedents to show that readers seem to honor such a tendency. PMID:17710192

  17. Electron optics with ballistic graphene junctions

    NASA Astrophysics Data System (ADS)

    Chen, Shaowen

    Electrons transmitted across a ballistic semiconductor junction undergo refraction, analogous to light rays across an optical boundary. A pn junction theoretically provides the equivalent of a negative index medium, enabling novel electron optics such as negative refraction and perfect (Veselago) lensing. In graphene, the linear dispersion and zero-gap bandstructure admit highly transparent pn junctions by simple electrostatic gating, which cannot be achieved in conventional semiconductors. Robust demonstration of these effects, however, has not been forthcoming. Here we employ transverse magnetic focusing to probe propagation across an electrostatically defined graphene junction. We find perfect agreement with the predicted Snell's law for electrons, including observation of both positive and negative refraction. Resonant transmission across the pn junction provides a direct measurement of the angle dependent transmission coefficient, and we demonstrate good agreement with theory. Comparing experimental data with simulation reveals the crucial role played by the effective junction width, providing guidance for future device design. Efforts toward sharper pn junction and possibility of zero field Veselago lensing will also be discussed. This work is supported by the Semiconductor Research Corporations NRI Center for Institute for Nanoelectronics Discovery and Exploration (INDEX).

  18. Influence of Na and Ga on the electrical properties of perfect 60° dislocations in Cu(In, Ga)Se2 thin-film photovoltaic absorbers

    NASA Astrophysics Data System (ADS)

    Barragan-Yani, D.; Albe, K.

    2018-04-01

    The segregation of GaIn and NaCu to perfect 60° dislocations in CuIn1-xGaxSe2 is investigated by means of density functional theory calculations. We find that the segregation process is mainly driven by the elastic interaction of both defect types with the strain field of the dislocation. GaIn moves into the negatively strained region, while NaCu is found in the positively strained region. We show that both defects affect the electronic defect levels induced by the dislocation core and GaIn is able to passivate the β-core in CuInSe2. This result indicates that β-cores are inactive in CuIn1-xGaxSe2. NaCu; however, they do not have a significant effect on the electrical properties of the studied dislocation cores. Therefore, the experimentally observed sodium segregation to dislocation cores in CuIn1-xGaxSe2 cannot be considered as the passivation mechanism of the electrically active cores in that material.

  19. Interpretation of the MEG-MUSIC scan in biomagnetic source localization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mosher, J.C.; Lewis, P.S.; Leahy, R.M.

    1993-09-01

    MEG-Music is a new approach to MEG source localization. MEG-Music is based on a spatio-temporal source model in which the observed biomagnetic fields are generated by a small number of current dipole sources with fixed positions/orientations and varying strengths. From the spatial covariance matrix of the observed fields, a signal subspace can be identified. The rank of this subspace is equal to the number of elemental sources present. This signal sub-space is used in a projection metric that scans the three dimensional head volume. Given a perfect signal subspace estimate and a perfect forward model, the metric will peak atmore » unity at each dipole location. In practice, the signal subspace estimate is contaminated by noise, which in turn yields MUSIC peaks which are less than unity. Previously we examined the lower bounds on localization error, independent of the choice of localization procedure. In this paper, we analyzed the effects of noise and temporal coherence on the signal subspace estimate and the resulting effects on the MEG-MUSIC peaks.« less

  20. Hit by a Perfect Storm? Art & Design in the National Student Survey

    ERIC Educational Resources Information Center

    Yorke, Mantz; Orr, Susan; Blair, Bernadette

    2014-01-01

    There has long been the suspicion amongst staff in Art & Design that the ratings given to their subject disciplines in the UK's National Student Survey are adversely affected by a combination of circumstances--a "perfect storm". The "perfect storm" proposition is tested by comparing ratings for Art & Design with those…

  1. Post-exercise heart-rate recovery correlates to resting heart-rate variability in healthy men.

    PubMed

    Molina, Guilherme Eckhardt; Fontana, Keila Elizabeth; Porto, Luiz Guilherme Grossi; Junqueira, Luiz Fernando

    2016-12-01

    The relationship between post-exercise heart-rate recovery (HRR) and resting cardiac autonomic modulation is an incompletely explored issue. To correlate HRR with resting supine and orthostatic autonomic status. HRR at the 1st, 3th, and 5th min following maximal treadmill exercise were correlated with 5-min time-domain (CV, pNN50 and rMSSD) and frequency-domain (TP, LF, HF, LFn, HFn, and LF/HF ratio) indices of heart-rate variability (HRV) in both supine and standing positions in 31 healthy physically active non-athletes men. Statistical analysis employed non-parametric tests with two-tailed p value set at 5 %. Absolute HRR and Δ %HRR at each post-exercise time did not correlated with HRV in supine position, as well as at 1st min in standing position. At the 3rd min and 5th min, these measures negatively correlated with pNN50, rMSSD, TP, and HF indices, and only in the 5th min, they showed negative correlation with HFn and positive correlation with LF, LFn, and LF/HF ratio in the standing position. Coefficient of HRR (CHRR) at the 1st min negatively correlated with pNN50 and rMSSD and at 3rd and 5th min showed positive correlation with LFn and LF/HF ratio in supine position. With HRV indices in standing position CHRR from the 1st to 5th min showed the same respective negative and positive correlations as the other measures. HRR from the 1st to 5th min post-exercise negatively correlated with parasympathetic modulation in resting orthostatic, but showed no correlation in supine position. At the 3rd and 5th min, a positive correlation with combined sympathetic-parasympathetic modulation in both positions was observed.

  2. Theoretical requirements for broadband perfect absorption of acoustic waves by ultra-thin elastic meta-films

    PubMed Central

    Duan, Yuetao; Luo, Jie; Wang, Guanghao; Hang, Zhi Hong; Hou, Bo; Li, Jensen; Sheng, Ping; Lai, Yun

    2015-01-01

    We derive and numerically demonstrate that perfect absorption of elastic waves can be achieved in two types of ultra-thin elastic meta-films: one requires a large value of almost pure imaginary effective mass density and a free space boundary, while the other requires a small value of almost pure imaginary effective modulus and a hard wall boundary. When the pure imaginary density or modulus exhibits certain frequency dispersions, the perfect absorption effect becomes broadband, even in the low frequency regime. Through a model analysis, we find that such almost pure imaginary effective mass density with required dispersion for perfect absorption can be achieved by elastic metamaterials with large damping. Our work provides a feasible approach to realize broadband perfect absorption of elastic waves in ultra-thin films. PMID:26184117

  3. Perfect fluid tori orbiting Kehagias-Sfetsos naked singularities

    NASA Astrophysics Data System (ADS)

    Stuchlík, Z.; Pugliese, D.; Schee, J.; Kučáková, H.

    2015-09-01

    We construct perfect fluid tori in the field of the Kehagias-Sfetsos (K-S) naked singularities. These are spherically symmetric vacuum solutions of the modified Hořava quantum gravity, characterized by a dimensionless parameter ω M^2, combining the gravitational mass parameter M of the spacetime with the Hořava parameter ω reflecting the role of the quantum corrections. In dependence on the value of ω M^2, the K-S naked singularities demonstrate a variety of qualitatively different behavior of their circular geodesics that is fully reflected in the properties of the toroidal structures, demonstrating clear distinction to the properties of the torii in the Schwarzschild spacetimes. In all of the K-S naked singularity spacetimes the tori are located above an "antigravity" sphere where matter can stay in a stable equilibrium position, which is relevant for the stability of the orbiting fluid toroidal accretion structures. The signature of the K-S naked singularity is given by the properties of marginally stable tori orbiting with the uniform distribution of the specific angular momentum of the fluid, l= const. In the K-S naked singularity spacetimes with ω M^2 > 0.2811, doubled tori with the same l= const can exist; mass transfer between the outer torus and the inner one is possible under appropriate conditions, while only outflow to the outer space is allowed in complementary conditions. In the K-S spacetimes with ω M^2 < 0.2811, accretion from cusped perfect fluid tori is not possible due to the non-existence of unstable circular geodesics.

  4. The role of material flexibility on the drying transition of water between hydrophobic objects: A thermodynamic analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Altabet, Y. Elia; Debenedetti, Pablo G., E-mail: pdebene@princeton.edu

    2014-11-14

    Liquid water confined between hydrophobic objects of sufficient size becomes metastable with respect to its vapor at separations smaller than a critical drying distance. Macroscopic thermodynamic arguments predicting this distance have been restricted to the limit of perfectly rigid confining materials. However, no material is perfectly rigid and it is of interest to account for this fact in the thermodynamic analysis. We present a theory that combines the current macroscopic theory with the thermodynamics of elasticity to derive an expression for the critical drying distance for liquids confined between flexible materials. The resulting expression is the sum of the well-knownmore » drying distance for perfectly rigid confining materials and a new term that accounts for flexibility. Thermodynamic arguments show that this new term is necessarily positive, meaning that flexibility increases the critical drying distance. To study the expected magnitude and scaling behavior of the flexible term, we consider the specific case of water and present an example of drying between thin square elastic plates that are simply supported along two opposite edges and free at the remaining two. We find that the flexible term can be the same order of magnitude or greater than the rigid solution for materials of biological interest at ambient conditions. In addition, we find that when the rigid solution scales with the characteristic size of the immersed objects, the flexible term is independent of size and vice versa. Thus, the scaling behavior of the overall drying distance will depend on the relative weights of the rigid and flexible contributions.« less

  5. Does the Consecutive Interpreting Approach enhance medical English communication skills of Japanese-speaking students?

    PubMed

    Iizuka, Hideki; Lefor, Alan K

    2018-04-19

    To determine if the Consecutive Interpreting Approach enhances medical English communication skills of students in a Japanese medical university and to assess this method based on performance and student evaluations.  This is a three-phase study using a mixed-methods design, which starts with four language reproduction activities for 30 medical and 95 nursing students, followed by a quantitative analysis of perfect-match reproduction rates to assess changes over the duration of the study and qualitative error analysis of participants' language reproduction. The final stage included a scored course evaluation and free-form comments to evaluate this approach and to identify effective educational strategies to enhance medical English communication skills. Mean perfect-match reproduction rates of all participants over four reproduction activities differed statistically significantly (repeated measures ANOVA, p<0.0005). The overall perfect-match reproduction rates improved from 75.3 % to 90.1 % for nursing and 89.5 % to 91.6% for medical students. The final achievement levels of nursing and medical students were equivalent (test of equivalence, p<0.05). Details of lexical- and syntactic-level errors were identified. The course evaluation scores were 3.74 (n=30, SD = 0.59) and 3.77 (n=90, SD=0.54) for medical and nursing students respectively. Participants' medical English communication skills are enhanced using this approach. Participants expressed positive feedback regarding this instruction method. This approach may be effective to enhance the language skills of non-native English-speaking students seeking to practice medicine in English speaking countries.

  6. Does the Consecutive Interpreting Approach enhance medical English communication skills of Japanese-speaking students?

    PubMed Central

    Lefor, Alan K.

    2018-01-01

    Objectives To determine if the Consecutive Interpreting Approach enhances medical English communication skills of students in a Japanese medical university and to assess this method based on performance and student evaluations.   Methods  This is a three-phase study using a mixed-methods design, which starts with four language reproduction activities for 30 medical and 95 nursing students, followed by a quantitative analysis of perfect-match reproduction rates to assess changes over the duration of the study and qualitative error analysis of participants' language reproduction. The final stage included a scored course evaluation and free-form comments to evaluate this approach and to identify effective educational strategies to enhance medical English communication skills. Results Mean perfect-match reproduction rates of all participants over four reproduction activities differed statistically significantly (repeated measures ANOVA, p<0.0005). The overall perfect-match reproduction rates improved from 75.3 % to 90.1 % for nursing and 89.5 % to 91.6% for medical students. The final achievement levels of nursing and medical students were equivalent (test of equivalence, p<0.05). Details of lexical- and syntactic-level errors were identified. The course evaluation scores were 3.74 (n=30, SD = 0.59) and 3.77 (n=90, SD=0.54) for medical and nursing students respectively. Conclusions Participants’ medical English communication skills are enhanced using this approach. Participants expressed positive feedback regarding this instruction method. This approach may be effective to enhance the language skills of non-native English-speaking students seeking to practice medicine in English speaking countries. PMID:29677693

  7. A contingency-based approach to the etiology of 'disorganized' attachment: the 'flickering switch' hypothesis.

    PubMed

    Koós, O; Gergely, G

    2001-01-01

    The authors present a new approach to the etiology of disorganized attachment based on contingency detection theory. According to this view, the relevant common factor in parental maltreatment and unresolved loss that leads to disorganized attachment has to do with the type of "deviant contingency environment" that both of these conditions generate. In such environments, infants experience periods of being in control followed by periods of sudden loss of control over the caregiver's behavior. The authors hypothesize that this adversely affects the developmental unfolding of the infant's innate "contingency detection module" (Gergely & Watson, 1999), which normally involves a maturational shift around 3 months from an initial attention bias for perfectly contingent stimulation to an emerging preference for less-than-perfect social contingencies. The periodically changing controllability of abusive and dissociating "unresolved" attachment figures is hypothesized to block this process and to lead to the defensive fixation of a dysfunctional "flickering contingency switch" mechanism with two dominant and competing target positions (self-oriented vs. other-oriented). This results in the dissociative style of attention and behavioral organization characteristic of disorganized infant attachment. The authors summarize the preliminary results of an empirical study that provides support for this model in 6.5-month-old infants using a modified Still-Face situation (the Mirror Interaction Situation). The study demonstrates differential emotional and behavioral reactions to sudden loss of maternal contingency and a specific interest in exploring the perfectly contingent self-image in the mirror in infants who at 12 months become categorized as "disorganized" in the Strange Situation.

  8. Nearly Perfect Fluidity in a High Temperature Superconductor

    DOE PAGES

    Rameau, J. D.; Reber, T. J.; Yang, H. -B.; ...

    2014-10-13

    Perfect fluids are characterized as having the smallest ratio of shear viscosity to entropy density, η/s, consistent with quantum uncertainty and causality. So far, nearly perfect fluids have only been observed in the quark-gluon plasma and in unitary atomic Fermi gases, exotic systems that are amongst the hottest and coldest objects in the known universe, respectively. We use angle resolved photoemission spectroscopy to measure the temperature dependence of an electronic analog of η/s in an optimally doped cuprate high-temperature superconductor, finding it too is a nearly perfect fluid around, and above, its superconducting transition temperature T c.

  9. Nearly perfect fluidity in a high-temperature superconductor

    NASA Astrophysics Data System (ADS)

    Rameau, J. D.; Reber, T. J.; Yang, H.-B.; Akhanjee, S.; Gu, G. D.; Johnson, P. D.; Campbell, S.

    2014-10-01

    Perfect fluids are characterized as having the smallest ratio of shear viscosity to entropy density, η /s, consistent with quantum uncertainty and causality. So far, nearly perfect fluids have only been observed in the quark-gluon plasma and in unitary atomic Fermi gases, exotic systems that are amongst the hottest and coldest objects in the known universe, respectively. We use angle resolved photoemission spectroscopy to measure the temperature dependence of an electronic analog of η /s in an optimally doped cuprate high-temperature superconductor, finding it too is a nearly perfect fluid around, and above, its superconducting transition temperature Tc.

  10. Linkage Disequilibrium and Inversion-Typing of the Drosophila melanogaster Genome Reference Panel

    PubMed Central

    Houle, David; Márquez, Eladio J.

    2015-01-01

    We calculated the linkage disequilibrium between all pairs of variants in the Drosophila Genome Reference Panel with minor allele count ≥5. We used r2 ≥ 0.5 as the cutoff for a highly correlated SNP. We make available the list of all highly correlated SNPs for use in association studies. Seventy-six percent of variant SNPs are highly correlated with at least one other SNP, and the mean number of highly correlated SNPs per variant over the whole genome is 83.9. Disequilibrium between distant SNPs is also common when minor allele frequency (MAF) is low: 37% of SNPs with MAF < 0.1 are highly correlated with SNPs more than 100 kb distant. Although SNPs within regions with polymorphic inversions are highly correlated with somewhat larger numbers of SNPs, and these correlated SNPs are on average farther away, the probability that a SNP in such regions is highly correlated with at least one other SNP is very similar to SNPs outside inversions. Previous karyotyping of the DGRP lines has been inconsistent, and we used LD and genotype to investigate these discrepancies. When previous studies agreed on inversion karyotype, our analysis was almost perfectly concordant with those assignments. In discordant cases, and for inversion heterozygotes, our results suggest errors in two previous analyses or discordance between genotype and karyotype. Heterozygosities of chromosome arms are, in many cases, surprisingly highly correlated, suggesting strong epsistatic selection during the inbreeding and maintenance of the DGRP lines. PMID:26068573

  11. Linkage Disequilibrium and Inversion-Typing of the Drosophila melanogaster Genome Reference Panel.

    PubMed

    Houle, David; Márquez, Eladio J

    2015-06-10

    We calculated the linkage disequilibrium between all pairs of variants in the Drosophila Genome Reference Panel with minor allele count ≥5. We used r(2) ≥ 0.5 as the cutoff for a highly correlated SNP. We make available the list of all highly correlated SNPs for use in association studies. Seventy-six percent of variant SNPs are highly correlated with at least one other SNP, and the mean number of highly correlated SNPs per variant over the whole genome is 83.9. Disequilibrium between distant SNPs is also common when minor allele frequency (MAF) is low: 37% of SNPs with MAF < 0.1 are highly correlated with SNPs more than 100 kb distant. Although SNPs within regions with polymorphic inversions are highly correlated with somewhat larger numbers of SNPs, and these correlated SNPs are on average farther away, the probability that a SNP in such regions is highly correlated with at least one other SNP is very similar to SNPs outside inversions. Previous karyotyping of the DGRP lines has been inconsistent, and we used LD and genotype to investigate these discrepancies. When previous studies agreed on inversion karyotype, our analysis was almost perfectly concordant with those assignments. In discordant cases, and for inversion heterozygotes, our results suggest errors in two previous analyses or discordance between genotype and karyotype. Heterozygosities of chromosome arms are, in many cases, surprisingly highly correlated, suggesting strong epsistatic selection during the inbreeding and maintenance of the DGRP lines. Copyright © 2015 Houle and Márquez.

  12. Coupled-oscillator theory of dispersion and Casimir-Polder interactions.

    PubMed

    Berman, P R; Ford, G W; Milonni, P W

    2014-10-28

    We address the question of the applicability of the argument theorem (of complex variable theory) to the calculation of two distinct energies: (i) the first-order dispersion interaction energy of two separated oscillators, when one of the oscillators is excited initially and (ii) the Casimir-Polder interaction of a ground-state quantum oscillator near a perfectly conducting plane. We show that the argument theorem can be used to obtain the generally accepted equation for the first-order dispersion interaction energy, which is oscillatory and varies as the inverse power of the separation r of the oscillators for separations much greater than an optical wavelength. However, for such separations, the interaction energy cannot be transformed into an integral over the positive imaginary axis. If the argument theorem is used incorrectly to relate the interaction energy to an integral over the positive imaginary axis, the interaction energy is non-oscillatory and varies as r(-4), a result found by several authors. Rather remarkably, this incorrect expression for the dispersion energy actually corresponds to the nonperturbative Casimir-Polder energy for a ground-state quantum oscillator near a perfectly conducting wall, as we show using the so-called "remarkable formula" for the free energy of an oscillator coupled to a heat bath [G. W. Ford, J. T. Lewis, and R. F. O'Connell, Phys. Rev. Lett. 55, 2273 (1985)]. A derivation of that formula from basic results of statistical mechanics and the independent oscillator model of a heat bath is presented.

  13. Evaluating and establishing national norms for mental wellbeing using the short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS): findings from the Health Survey for England.

    PubMed

    Ng Fat, Linda; Scholes, Shaun; Boniface, Sadie; Mindell, Jennifer; Stewart-Brown, Sarah

    2017-05-01

    The Warwick-Edinburgh Mental Well-being Scale (WEMWBS), 14 positively worded statements, is a validated instrument to measure mental wellbeing on a population level. Less is known about the population distribution of the shorter seven-item version (SWEMWBS) or its performance as an instrument to measure wellbeing. Using the Health Survey for England 2010-2013 (n = 27,169 adults aged 16+, nationally representative of the population), age- and sex-specific norms were estimated using means and percentiles. Criterion validity was examined using: (1) Spearman correlations (ρ) for SWEMWBS with General Health Questionnaire (GHQ-12), happiness index, EQ-VAS (2) a multinomial logit model with SWEMWBS (low, medium and high wellbeing) as the outcome and demographic, social and health behaviours as explanatory variables. Relative validity was examined by comparing SWEMWBS with WEMWBS using: (1) Spearman correlations (continuous data), and (2) the weighted kappa statistic (categorical), within population subgroups. Mean (median) SWEMWBS was 23.7 (23.2) for men and 23.2 (23.2) for women (p = 0.100). Spearman correlations were moderately sized for the happiness index (ρ = 0.53, P < 0.001), GHQ-12 (ρ = -0.52, p < 0.001) and EQ-VAS (ρ = 0.40, p < 0.001). Participants consuming <1 portion of fruit and vegetables a day versus ≥5 (odds ratio = 1.43 95% Confidence Interval = (1.22-1.66)) and current smokers versus non-smokers (1.28 (1.15-1.41)) were more likely to have low vs medium wellbeing. Participants who binge drank versus non-drinkers were less likely to have high versus medium wellbeing (0.81 (0.71-0.92)). Spearman correlations between SWEMWBS and WEMWBS were above 0.95; weighted kappa statistics showed almost perfect agreement (0.79-0.85). SWEMWBS distinguishes mental wellbeing between subgroups, similarly to WEMWBS, but is less sensitive to gender differences.

  14. Autophagy promotes synapse development in Drosophila.

    PubMed

    Shen, Wei; Ganetzky, Barry

    2009-10-05

    Autophagy, a lysosome-dependent degradation mechanism, mediates many biological processes, including cellular stress responses and neuroprotection. In this study, we demonstrate that autophagy positively regulates development of the Drosophila melanogaster larval neuromuscular junction (NMJ). Autophagy induces an NMJ overgrowth phenotype closely resembling that of highwire (hiw), an E3 ubiquitin ligase mutant. Moreover, like hiw, autophagy-induced NMJ overgrowth is suppressed by wallenda (wnd) and by a dominant-negative c-Jun NH(2)-terminal kinase (bsk(DN)). We show that autophagy promotes NMJ growth by reducing Hiw levels. Thus, autophagy and the ubiquitin-proteasome system converge in regulating synaptic development. Because autophagy is triggered in response to many environmental cues, our findings suggest that it is perfectly positioned to link environmental conditions with synaptic growth and plasticity.

  15. Alternative Fuels Data Center: Deploying Clean Buses in Texas through

    Science.gov Websites

    money for large expenditures--new school buses are a perfect example and offer the perfect opportunity a potential penalty or fine when that money is put toward an SEP. Municipalities may offset 100% of the problem schools have with finding money for large expenditures-new school buses are a perfect

  16. The Perfect Eye A Novel Model for Teaching the Theory of Refraction.

    ERIC Educational Resources Information Center

    Kurtz, Daniel

    1999-01-01

    The Perfect Eye model simplifies solutions to a wide variety of optometry instructional problems by facilitating student understanding of the interaction among lenses, objects, accommodation, and ametropia. The model is based on the premise that inside every eye is a perfect (emmetropic) eye, and that the physiological eye is a combination of the…

  17. Innovative Writing Instruction: Practice Makes Perfect! Realizing Classrooms as "Landscapes of Learning," Not Places of Perfection

    ERIC Educational Resources Information Center

    Ozier, Lance

    2011-01-01

    Pressure for students to produce writing perfection in the classroom often eclipses the emphasis placed on the need for students to practice writing. Occasions for students to choose, challenge, and reflect--to actually risk risking--are too often absent from conversations among students and teachers in countless English classrooms. Tom Romano…

  18. Research on Knowledge-Based Optimization Method of Indoor Location Based on Low Energy Bluetooth

    NASA Astrophysics Data System (ADS)

    Li, C.; Li, G.; Deng, Y.; Wang, T.; Kang, Z.

    2017-09-01

    With the rapid development of LBS (Location-based Service), the demand for commercialization of indoor location has been increasing, but its technology is not perfect. Currently, the accuracy of indoor location, the complexity of the algorithm, and the cost of positioning are hard to be simultaneously considered and it is still restricting the determination and application of mainstream positioning technology. Therefore, this paper proposes a method of knowledge-based optimization of indoor location based on low energy Bluetooth. The main steps include: 1) The establishment and application of a priori and posterior knowledge base. 2) Primary selection of signal source. 3) Elimination of positioning gross error. 4) Accumulation of positioning knowledge. The experimental results show that the proposed algorithm can eliminate the signal source of outliers and improve the accuracy of single point positioning in the simulation data. The proposed scheme is a dynamic knowledge accumulation rather than a single positioning process. The scheme adopts cheap equipment and provides a new idea for the theory and method of indoor positioning. Moreover, the performance of the high accuracy positioning results in the simulation data shows that the scheme has a certain application value in the commercial promotion.

  19. From the generalized reflection law to the realization of perfect anomalous reflectors

    PubMed Central

    Díaz-Rubio, Ana; Asadchy, Viktar S.; Elsakka, Amr; Tretyakov, Sergei A.

    2017-01-01

    The use of the generalized Snell’s law opens wide possibilities for the manipulation of transmitted and reflected wavefronts. However, known structures designed to shape reflection wavefronts suffer from significant parasitic reflections in undesired directions. We explore the limitations of the existing solutions for the design of passive planar reflectors and demonstrate that strongly nonlocal response is required for perfect performance. A new paradigm for the design of perfect reflectors based on energy surface channeling is introduced. We realize and experimentally verify a perfect design of an anomalously reflective surface using an array of rectangular metal patches backed by a metallic plate. This conceptually new mechanism for wavefront manipulation allows the design of thin perfect reflectors, offering a versatile design method applicable to other scenarios, such as focusing reflectors, surface wave manipulations, or metasurface holograms, extendable to other frequencies. PMID:28819642

  20. Reliability and validity of the range of motion scale (ROMS) in patients with abnormal postures.

    PubMed

    van Rooijen, Diana E; Lalli, Stefania; Marinus, Johan; Maihöfner, Christian; McCabe, Candida S; Munts, Alex G; van der Plas, Anton A; Tijssen, Marina A J; van de Warrenburg, Bart P; Albanese, Alberto; van Hilten, Jacobus J

    2015-03-01

    Sustained abnormal postures (i.e., fixed dystonia) are the most frequently reported motor abnormalities in complex regional pain syndrome (CRPS), but these symptoms may also develop after peripheral trauma without CRPS. Currently, there is no valid and reliable measurement instrument available to measure the severity and distribution of these postures. The range of motion scale (ROMS) was therefore developed to assess the severity based on the possible active range of motion of all joints (arms, legs, trunk, and neck), and the present study evaluates its reliability and validity. Inter- and intra-rater reliability of the ROMS was determined in 16 patients with abnormal sustained postures, who were videotaped following a standard video protocol in a university hospital. The recordings were rated by a panel of international experts. In addition, 30 patients were clinically tested with both the Burke-Fahn-Marsden (BFM) scale as well as the ROMS to assess construct validity. Inter-rater reliability for total ROMS scores showed an intra-class correlation coefficient (ICC) of 0.85. The majority of the scores for the separate joints (13 out of 18) demonstrated an almost perfect agreement with ICCs ranging from 0.81 to 0.94; of the other items, one showed fair, one moderate, and three substantial agreement. The ICCs for the intra-rater reliability ranged from moderate to almost perfect (0.68-0.98). Spearman's correlation coefficients between corresponding body areas as measured with the ROMS or BFM were all above 0.82. The ROMS is a reliable and valid instrument to evaluate the severity and distribution of sustained abnormal postures. Wiley Periodicals, Inc.

  1. Strategies for Efficient Computation of the Expected Value of Partial Perfect Information

    PubMed Central

    Madan, Jason; Ades, Anthony E.; Price, Malcolm; Maitland, Kathryn; Jemutai, Julie; Revill, Paul; Welton, Nicky J.

    2014-01-01

    Expected value of information methods evaluate the potential health benefits that can be obtained from conducting new research to reduce uncertainty in the parameters of a cost-effectiveness analysis model, hence reducing decision uncertainty. Expected value of partial perfect information (EVPPI) provides an upper limit to the health gains that can be obtained from conducting a new study on a subset of parameters in the cost-effectiveness analysis and can therefore be used as a sensitivity analysis to identify parameters that most contribute to decision uncertainty and to help guide decisions around which types of study are of most value to prioritize for funding. A common general approach is to use nested Monte Carlo simulation to obtain an estimate of EVPPI. This approach is computationally intensive, can lead to significant sampling bias if an inadequate number of inner samples are obtained, and incorrect results can be obtained if correlations between parameters are not dealt with appropriately. In this article, we set out a range of methods for estimating EVPPI that avoid the need for nested simulation: reparameterization of the net benefit function, Taylor series approximations, and restricted cubic spline estimation of conditional expectations. For each method, we set out the generalized functional form that net benefit must take for the method to be valid. By specifying this functional form, our methods are able to focus on components of the model in which approximation is required, avoiding the complexities involved in developing statistical approximations for the model as a whole. Our methods also allow for any correlations that might exist between model parameters. We illustrate the methods using an example of fluid resuscitation in African children with severe malaria. PMID:24449434

  2. Enhanced Telecom Emission from Single Group-IV Quantum Dots by Precise CMOS-Compatible Positioning in Photonic Crystal Cavities.

    PubMed

    Schatzl, Magdalena; Hackl, Florian; Glaser, Martin; Rauter, Patrick; Brehm, Moritz; Spindlberger, Lukas; Simbula, Angelica; Galli, Matteo; Fromherz, Thomas; Schäffler, Friedrich

    2017-03-15

    Efficient coupling to integrated high-quality-factor cavities is crucial for the employment of germanium quantum dot (QD) emitters in future monolithic silicon-based optoelectronic platforms. We report on strongly enhanced emission from single Ge QDs into L3 photonic crystal resonator (PCR) modes based on precise positioning of these dots at the maximum of the respective mode field energy density. Perfect site control of Ge QDs grown on prepatterned silicon-on-insulator substrates was exploited to fabricate in one processing run almost 300 PCRs containing single QDs in systematically varying positions within the cavities. Extensive photoluminescence studies on this cavity chip enable a direct evaluation of the position-dependent coupling efficiency between single dots and selected cavity modes. The experimental results demonstrate the great potential of the approach allowing CMOS-compatible parallel fabrication of arrays of spatially matched dot/cavity systems for group-IV-based data transfer or quantum optical systems in the telecom regime.

  3. Enhanced Telecom Emission from Single Group-IV Quantum Dots by Precise CMOS-Compatible Positioning in Photonic Crystal Cavities

    PubMed Central

    2017-01-01

    Efficient coupling to integrated high-quality-factor cavities is crucial for the employment of germanium quantum dot (QD) emitters in future monolithic silicon-based optoelectronic platforms. We report on strongly enhanced emission from single Ge QDs into L3 photonic crystal resonator (PCR) modes based on precise positioning of these dots at the maximum of the respective mode field energy density. Perfect site control of Ge QDs grown on prepatterned silicon-on-insulator substrates was exploited to fabricate in one processing run almost 300 PCRs containing single QDs in systematically varying positions within the cavities. Extensive photoluminescence studies on this cavity chip enable a direct evaluation of the position-dependent coupling efficiency between single dots and selected cavity modes. The experimental results demonstrate the great potential of the approach allowing CMOS-compatible parallel fabrication of arrays of spatially matched dot/cavity systems for group-IV-based data transfer or quantum optical systems in the telecom regime. PMID:28345012

  4. Point -of -care testing (POCT) in molecular diagnostics: Performance evaluation of GeneXpert HCV RNA test in diagnosing and monitoring of HCV infection.

    PubMed

    Gupta, Ekta; Agarwala, Pragya; Kumar, Guresh; Maiwall, Rakhi; Sarin, Shiv Kumar

    2017-03-01

    Molecular testing at the point-of-care may turn out to be game changer for HCV diagnosis and treatment monitoring, through increased sensitivity, reduced turnaround time, and ease of performance. One such assay GeneXpert ® has recently been released. Comparative analysis between performances of GeneXpert ® and Abbott HCV-RNA was done. 174 HCV infected patients were recruited and, one time plasma samples from 154 patients and repeated samples from 20 patients, obtained at specific treatment time-points (0, 4, 12 and 24) weeks were serially re-tested on Xpert ® . Genotype 3 was the commonest, seen in 80 (66%) of the cases, genotype 1 in 34 (28.3%), genotype 4 in 4 (3.3%) and genotypes 2 and 5 in 1 (0.8%) each. Median HCV RNA load was 4.69 log 10 (range: 0-6.98log 10 ) IU/ml. Overall a very good correlation was seen between the two assays (R 2 =0.985), concordance of the results between the assays was seen in 138 samples (89.6%). High and low positive standards were tested ten times on Xpert ® to evaluate the precision and the coefficient of variation was 0.01 for HPC and 0.07 for the LPC. Monitoring of patients on two different regimes of treatment, pegylated interferon plus ribavirin and sofosbuvir plus ribavirin was done by both the systems at baseline, 4, 12 and 24 weeks. Perfect correlation between the assays in the course of therapy at different treatment time- point in genotypes 3 and 1 was seen. The study demonstrates excellent performance of the Xpert ® HCV assay in viral load assessment and in treatment course monitoring consistency. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Breast Density Estimation with Fully Automated Volumetric Method: Comparison to Radiologists' Assessment by BI-RADS Categories.

    PubMed

    Singh, Tulika; Sharma, Madhurima; Singla, Veenu; Khandelwal, Niranjan

    2016-01-01

    The objective of our study was to calculate mammographic breast density with a fully automated volumetric breast density measurement method and to compare it to breast imaging reporting and data system (BI-RADS) breast density categories assigned by two radiologists. A total of 476 full-field digital mammography examinations with standard mediolateral oblique and craniocaudal views were evaluated by two blinded radiologists and BI-RADS density categories were assigned. Using a fully automated software, mean fibroglandular tissue volume, mean breast volume, and mean volumetric breast density were calculated. Based on percentage volumetric breast density, a volumetric density grade was assigned from 1 to 4. The weighted overall kappa was 0.895 (almost perfect agreement) for the two radiologists' BI-RADS density estimates. A statistically significant difference was seen in mean volumetric breast density among the BI-RADS density categories. With increased BI-RADS density category, increase in mean volumetric breast density was also seen (P < 0.001). A significant positive correlation was found between BI-RADS categories and volumetric density grading by fully automated software (ρ = 0.728, P < 0.001 for first radiologist and ρ = 0.725, P < 0.001 for second radiologist). Pairwise estimates of the weighted kappa between Volpara density grade and BI-RADS density category by two observers showed fair agreement (κ = 0.398 and 0.388, respectively). In our study, a good correlation was seen between density grading using fully automated volumetric method and density grading using BI-RADS density categories assigned by the two radiologists. Thus, the fully automated volumetric method may be used to quantify breast density on routine mammography. Copyright © 2016 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  6. Comparison of Para-Selles Bailenger/Kop-Color Fumouze, Para-Selles-Iodésine/Kop-Color II Fumouze diagnostic kits with conventional microscopic methods in identifying intestinal parasitic diseases in Senegal.

    PubMed

    Sow, Doudou; Dieng, Yémou; Haouchine, Djamal; Niang, Khadim; Niang, Thiane; Sylla, Khadime; Tine, Roger Clément; Ndiaye, Magatte; Ndiaye, Jean Louis; Faye, Babacar; Faye, Omar; Gaye, Oumar; Dieng, Thérèse; Izri, Arezki

    2017-09-01

    In the context of controlling intestinal parasites, accurate diagnosis is essential. Our objective was to evaluate the performance of new diagnostic kits compared to conventional microscopic methods in identifying intestinal parasites. Faeces collected in rural area in Senegal were subjected to several detection techniques. Thus, the sensitivity, specificity, positive and negative predictive values of new diagnostic techniques were compared to conventional merthiolate-iodine-formalin, conventional Bailenger and modified Ritchie. Furthermore, the kappa coefficient was calculated to evaluate the correlation between the new kit and those of modified Ritchie. Out of the 117 patients examined, 102 presented with a parasite, or prevalence of 87.1%. The Fumouze techniques proved to be as effective as the conventional methods in detecting flagellates and helminths with sensitivities ranging from 97 to 100%. However, conventional techniques were slightly more sensitive in identifying Endolimax nana and Blastocystis hominis . The correlation was nearly perfect (k = 0.83 and 1), respectively between Bailenger Fumouze, Iodesine Fumouze and modified Ritchie in identifying helminths while it was just acceptable (k = 0.27 and 0.28) in identifying B. hominis . The modified Ritchie technique routinely used in our laboratory remains a good diagnostic tool. However, the use of kit techniques was interesting when reading the pellet after concentration and the Colour KOP staining was a considerable contribution to the diagnosis of the vegetative forms. Therefore, it would be interesting to determine the cost of a stool test using Fumouze kit techniques to provide the most cost effective way.

  7. Estimating indices of range shifts in birds using dynamic models when detection is imperfect

    USGS Publications Warehouse

    Clement, Matthew J.; Hines, James E.; Nichols, James D.; Pardieck, Keith L.; Ziolkowski, David J.

    2016-01-01

    There is intense interest in basic and applied ecology about the effect of global change on current and future species distributions. Projections based on widely used static modeling methods implicitly assume that species are in equilibrium with the environment and that detection during surveys is perfect. We used multiseason correlated detection occupancy models, which avoid these assumptions, to relate climate data to distributional shifts of Louisiana Waterthrush in the North American Breeding Bird Survey (BBS) data. We summarized these shifts with indices of range size and position and compared them to the same indices obtained using more basic modeling approaches. Detection rates during point counts in BBS surveys were low, and models that ignored imperfect detection severely underestimated the proportion of area occupied and slightly overestimated mean latitude. Static models indicated Louisiana Waterthrush distribution was most closely associated with moderate temperatures, while dynamic occupancy models indicated that initial occupancy was associated with diurnal temperature ranges and colonization of sites was associated with moderate precipitation. Overall, the proportion of area occupied and mean latitude changed little during the 1997–2013 study period. Near-term forecasts of species distribution generated by dynamic models were more similar to subsequently observed distributions than forecasts from static models. Occupancy models incorporating a finite mixture model on detection – a new extension to correlated detection occupancy models – were better supported and may reduce bias associated with detection heterogeneity. We argue that replacing phenomenological static models with more mechanistic dynamic models can improve projections of future species distributions. In turn, better projections can improve biodiversity forecasts, management decisions, and understanding of global change biology.

  8. von Willebrand factor as a novel noninvasive predictor of portal hypertension and esophageal varices in hepatitis B patients with cirrhosis.

    PubMed

    Wu, Hao; Yan, Shiping; Wang, Guangchuan; Cui, Shaobo; Zhang, Chunqing; Zhu, Qiang

    2015-01-01

    At present, there is no perfect noninvasive method to assess portal hypertension and esophageal varices. Early predicting esophageal varices can provide evidence for managing cirrhotic patients. We aimed to further investigate von Willebrand factor (vWF) as a noninvasive predictor of portal hypertension, especially of esophageal varices. A total of 60 hepatitis B patients with cirrhosis and 45 healthy subjects were enrolled in this study. Levels of six markers were examined. All patients underwent hepatic venous pressure gradient (HVPG) and esophagogastroduodenoscopy. We evaluated the performance of six factors for diagnosis of portal hypertension and esophageal varices. The vWF levels in liver tissues were observed by immunohistochemistry. Correlations between the level of vWF in liver tissues and HVPG and between levels of vWF in tissues and plasma were examined. Cutoff values of plasma vWF (1510.5 mU/mL and 1701 mU/mL) showed high positive predictive value (PPV, 90.2% and 87.5%) in predicting clinically significant portal hypertension and severe portal hypertension. Cutoff values of vWF (1414 mU/ml and 1990 mU/mL, PPV 90.3% and 86.3%, respectively) were provided to detect the presence and degree of esophageal varices. Linear correlations were observed between levels of vWF in liver tissues and HVPG (r(2) = 0.552, p < 0.001) and between the level of vWF in liver tissues and in plasma (r(2) = 0.461, p < 0.001). The vWF is a noninvasive predictor of portal hypertension and esophageal varices in hepatitis B patients with cirrhosis. Increased levels of vWF in liver tissues may induce the elevated plasma vWF levels, but molecular mechanism is needed for further study.

  9. Visibility vs. biomass in flowers: exploring corolla allocation in Mediterranean entomophilous plants

    PubMed Central

    Herrera, Javier

    2009-01-01

    Background and Aims While pollinators may in general select for large, morphologically uniform floral phenotypes, drought stress has been proposed as a destabilizing force that may favour small flowers and/or promote floral variation within species. Methods The general validity of this concept was checked by surveying a taxonomically diverse array of 38 insect-pollinated Mediterranean species. The interplay between fresh biomass investment, linear size and percentage corolla allocation was studied. Allometric relationships between traits were investigated by reduced major-axis regression, and qualitative correlates of floral variation explored using general linear-model MANOVA. Key Results Across species, flowers were perfectly isometrical with regard to corolla allocation (i.e. larger flowers were just scaled-up versions of smaller ones and vice versa). In contrast, linear size and biomass varied allometrically (i.e. there were shape variations, in addition to variations in size). Most floral variables correlated positively and significantly across species, except corolla allocation, which was largely determined by family membership and floral symmetry. On average, species with bilateral flowers allocated more to the corolla than those with radial flowers. Plant life-form was immaterial to all of the studied traits. Flower linear size variation was in general low among conspecifics (coefficients of variation around 10 %), whereas biomass was in general less uniform (e.g. 200–400 mg in Cistus salvifolius). Significant among-population differences were detected for all major quantitative floral traits. Conclusions Flower miniaturization can allow an improved use of reproductive resources under prevailingly stressful conditions. The hypothesis that flower size reflects a compromise between pollinator attraction, water requirements and allometric constraints among floral parts is discussed. PMID:19258340

  10. SU-F-E-20: A Mathematical Model of Linac Jaw Calibration Integrated with Collimator Walkout

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhao, Y; Corns, R; Huang, V

    2016-06-15

    Purpose: Accurate jaw calibration is possible, but it does not necessarily achieve good junctions because of collimator rotation walkout. We developed a mathematical model seeking to pick an origin for calibration that minimizes the collimator walkout effect. Methods: We use radioopaque markers aligned with crosshair on the EPID to determine the collimator walkout at collimator angles 0°, 90° and 270°. We can accurately calibrate jaws to any arbitrary origin near the radiation field centre. While the absolute position of an origin moves with the collimator walkout, its relative location to the crosshair is an invariant. We studied two approaches tomore » select an optimal origin. One approach seeks to bring all three origin locations (0°–90°–270°) as close as possible by minimizing the perimeter of the triangle formed by these points. The other approach focuses on the gap for 0°–90° junctions. Results: Our perimeter cost function has two variables and non-linear behaviour. Generally, it does not have zero-perimeter-length solution which leads to perfect jaw matches. The zero solution can only be achieved, if the collimator rotates about a single fixed axis. In the second approach, we can always get perfect 0°–0° and 0°–90° junctions, because we ignore the 0°–270° situation. For our TrueBeams, both techniques for selecting an origin improved junction dose inhomogeneities to less than ±6%. Conclusion: Our model considers the general jaw matching with collimator rotations and proposes two potential solutions. One solution optimizes the junction gaps by considering all three collimator angles while the other only considers 0°–90°. The first solution will not give perfect matching, but can be clinically acceptable with minimized collimator walkout effect, while the second can have perfect junctions at the expense of the 0°–270° junctions. Different clinics might choose between these two methods basing on their clinical practices.« less

  11. Approaching Methodology Creatively: Problematizing Elite Schools' "Best Practice" through a Film about Perfection and Imperfection

    ERIC Educational Resources Information Center

    Fahey, Johannah; Prosser, Howard

    2015-01-01

    Elite schools around the world aspire to produce perfect students and yet there are always obstacles to this perfection being achieved. In this paper, we suggest that this process of perfectionism and obstruction can best be understood using a methodology that looks to the creative arts, rather than the usual social science orthodoxies. Our focus…

  12. Orbital angular momentum modes of high-gain parametric down-conversion

    NASA Astrophysics Data System (ADS)

    Beltran, Lina; Frascella, Gaetano; Perez, Angela M.; Fickler, Robert; Sharapova, Polina R.; Manceau, Mathieu; Tikhonova, Olga V.; Boyd, Robert W.; Leuchs, Gerd; Chekhova, Maria V.

    2017-04-01

    Light beams with orbital angular momentum (OAM) are convenient carriers of quantum information. They can also be used for imparting rotational motion to particles and providing high resolution in imaging. Due to the conservation of OAM in parametric down-conversion (PDC), signal and idler photons generated at low gain have perfectly anti-correlated OAM values. It is interesting to study the OAM properties of high-gain PDC, where the same OAM modes can be populated with large, but correlated, numbers of photons. Here we investigate the OAM spectrum of high-gain PDC and show that the OAM mode content can be controlled by varying the pump power and the configuration of the source. In our experiment, we use a source consisting of two nonlinear crystals separated by an air gap. We discuss the OAM properties of PDC radiation emitted by this source and suggest possible modifications.

  13. Applying a simple three-dimensional eddy correlation system for latent and sensible heat flux to contrasting forest canopies

    NASA Astrophysics Data System (ADS)

    Bernhofer, Ch.

    1992-06-01

    A simple eddy correlation system is presented that allows on-line calculation of latent and sensible heat fluxes. The system is composed of a three dimensional propeller anemometer, a thermocouple and a capacitance relative humidity sensor. Results from two contrasting sites demonstrate the capability of the system to measure turbulent fluxes under varying conditions. A dry mixed (dominantly coniferous) forest in hilly terrain in Austria is compared to a well irrigated, heavily transpiring, deciduous pecan orchard in the Southwest of the US. The US site shows insufficient closure of the energy balance that is attributed to non-turbulent fluxes under advective conditions in a stable boundary layer (Blanford et al., 1991) while the Austrian site exhibits almost perfect closure with the use of the very same instruments when the boundary layer is convective and advection is negligible.

  14. Influence of internal channel geometry of gas turbine blade on flow structure and heat transfer

    NASA Astrophysics Data System (ADS)

    Szwaba, Ryszard; Kaczynski, Piotr; Telega, Janusz; Doerffer, Piotr

    2017-12-01

    This paper presents the study of the influence of channel geometry on the flow structure and heat transfer, and also their correlations on all the walls of a radial cooling passage model of a gas turbine blade. The investigations focus on the heat transfer and aerodynamic measurements in the channel, which is an accurate representation of the configuration used in aeroengines. Correlations for the heat transfer coefficient and the pressure drop used in the design of internal cooling passages are often developed from simplified models. It is important to note that real engine passages do not have perfect rectangular cross sections, but include a corner fillets, ribs with fillet radii and a special orientation. Therefore, this work provides detailed fluid flow and heat transfer data for a model of radial cooling geometry which has very realistic features.

  15. Collinearity and Causal Diagrams: A Lesson on the Importance of Model Specification.

    PubMed

    Schisterman, Enrique F; Perkins, Neil J; Mumford, Sunni L; Ahrens, Katherine A; Mitchell, Emily M

    2017-01-01

    Correlated data are ubiquitous in epidemiologic research, particularly in nutritional and environmental epidemiology where mixtures of factors are often studied. Our objectives are to demonstrate how highly correlated data arise in epidemiologic research and provide guidance, using a directed acyclic graph approach, on how to proceed analytically when faced with highly correlated data. We identified three fundamental structural scenarios in which high correlation between a given variable and the exposure can arise: intermediates, confounders, and colliders. For each of these scenarios, we evaluated the consequences of increasing correlation between the given variable and the exposure on the bias and variance for the total effect of the exposure on the outcome using unadjusted and adjusted models. We derived closed-form solutions for continuous outcomes using linear regression and empirically present our findings for binary outcomes using logistic regression. For models properly specified, total effect estimates remained unbiased even when there was almost perfect correlation between the exposure and a given intermediate, confounder, or collider. In general, as the correlation increased, the variance of the parameter estimate for the exposure in the adjusted models increased, while in the unadjusted models, the variance increased to a lesser extent or decreased. Our findings highlight the importance of considering the causal framework under study when specifying regression models. Strategies that do not take into consideration the causal structure may lead to biased effect estimation for the original question of interest, even under high correlation.

  16. Whole lesion histogram analysis of meningiomas derived from ADC values. Correlation with several cellularity parameters, proliferation index KI 67, nucleic content, and membrane permeability.

    PubMed

    Surov, Alexey; Hamerla, Gordian; Meyer, Hans Jonas; Winter, Karsten; Schob, Stefan; Fiedler, Eckhard

    2018-09-01

    To analyze several histopathological features and their possible correlations with whole lesion histogram analysis derived from ADC maps in meningioma. The retrospective study involved 36 patients with primary meningiomas. For every tumor, the following histogram analysis parameters of apparent diffusion coefficient (ADC) were calculated: ADC mean , ADC max , ADC min , ADC median , ADC mode , ADC percentiles: P10, P25, P75, P90, as well kurtosis, skewness, and entropy. All measures were performed by two radiologists. Proliferation index KI 67, minimal, maximal and mean cell count, total nucleic area, and expression of water channel aquaporin 4 (AQP4) were estimated. Spearman's correlation coefficient was used to analyze associations between investigated parameters. A perfect interobserver agreement for all ADC values (0.84-0.97) was identified. All ADC values correlated inversely with tumor cellularity with the strongest correlation between P10, P25 and mean cell count (-0.558). KI 67 correlated inversely with all ADC values except ADC min . ADC parameters did not correlate with total nucleic area. All ADC values correlated statistically significant with expression of AQP4. ADC histogram analysis is a valid method with an excellent interobserver agreement. Cellularity parameters and proliferation potential are associated with different ADC values. Membrane permeability may play a greater role for water diffusion than cell count and proliferation activity. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. Laser Opto-Electronic Correlator for Robotic Vision Automated Pattern Recognition

    NASA Technical Reports Server (NTRS)

    Marzwell, Neville

    1995-01-01

    A compact laser opto-electronic correlator for pattern recognition has been designed, fabricated, and tested. Specifically it is a translation sensitivity adjustable compact optical correlator (TSACOC) utilizing convergent laser beams for the holographic filter. Its properties and performance, including the location of the correlation peak and the effects of lateral and longitudinal displacements for both filters and input images, are systematically analyzed based on the nonparaxial approximation for the reference beam. The theoretical analyses have been verified in experiments. In applying the TSACOC to important practical problems including fingerprint identification, we have found that the tolerance of the system to the input lateral displacement can be conveniently increased by changing a geometric factor of the system. The system can be compactly packaged using the miniature laser diode sources and can be used in space by the National Aeronautics and Space Administration (NASA) and ground commercial applications which include robotic vision, and industrial inspection of automated quality control operations. The personnel of Standard International will work closely with the Jet Propulsion Laboratory (JPL) to transfer the technology to the commercial market. Prototype systems will be fabricated to test the market and perfect the product. Large production will follow after successful results are achieved.

  18. Excited state correlations of the finite Heisenberg chain

    NASA Astrophysics Data System (ADS)

    Pozsgay, Balázs

    2017-02-01

    We consider short range correlations in excited states of the finite XXZ and XXX Heisenberg spin chains. We conjecture that the known results for the factorized ground state correlations can be applied to the excited states too, if the so-called physical part of the construction is changed appropriately. For the ground state we derive simple algebraic expressions for the physical part; the formulas only use the ground state Bethe roots as an input. We conjecture that the same formulas can be applied to the excited states as well, if the exact Bethe roots of the excited states are used instead. In the XXZ chain the results are expected to be valid for all states (except certain singular cases where regularization is needed), whereas in the XXX case they only apply to singlet states or group invariant operators. Our conjectures are tested against numerical data from exact diagonalization and coordinate Bethe Ansatz calculations, and perfect agreement is found in all cases. In the XXX case we also derive a new result for the nearest-neighbour correlator < σ 1zσ 2z> , which is valid for non-singlet states as well. Our results build a bridge between the known theory of factorized correlations, and the recently conjectured TBA-like description for the building blocks of the construction.

  19. Flexibility of resource allocation in a hermaphroditic-gynomonoecious herb through deployment of female and male resources in perfect flowers.

    PubMed

    Mamut, Jannathan; Xiong, Ying-Ze; Tan, Dun-Yan; Huang, Shuang-Quan

    2017-03-01

    It has been hypothesized that two flower types permit flexible allocation of resources to female and male functions, yet empirical evidence for the sex-allocation hypothesis remains scarce in gynomonoecious species. To characterize resource allocation to pistillate and perfect flowers and allocation of perfect flowers between gynomonoecious and hermaphroditic individuals, we examined the flexibility and whether female-biased allocation increases with plant size in the hermaphroditic-gynomonoecious herb Eremurus anisopterus . Frequency of gynomonoecious individuals, flower production, and plant size were investigated in different populations. Floral allocation was compared among the three flower types of E. anisopterus . Frequency of gynomonoecious plants varied from 2-17% in nine populations. Only larger plants produced female flowers at the bottom of racemes. Both female and perfect flower production tended to increase proportionately with plant size in gynomonoecious individuals. Female flowers did not produce less biomass than perfect flowers from hermaphroditic or gynomonoecious plants. However, both female and perfect flowers from gynomonoecious individuals had lighter stamen mass, but larger pistil mass, than perfect flowers from hermaphrodites. Although the prediction of an increase in female flower number with plant size was not observed in E. anisopterus , the flexibility of sex allocation in gynomonoecious species was confirmed in that gynomonoecious individuals had a female-biased floral allocation compared to hermaphroditic individuals. Such comparisons of gynomonoecious to hermaphroditic individuals permit us to unveil a sexual adjustment strategy: flexibility of sexual investments within plants. © 2017 Botanical Society of America.

  20. The covariant entropy conjecture and concordance cosmological models

    NASA Astrophysics Data System (ADS)

    He, Song; Zhang, Hongbao

    2008-10-01

    Recently a covariant entropy conjecture has been proposed for dynamical horizons. We apply this conjecture to concordance cosmological models, namely, those cosmological models filled with perfect fluids, in the presence of a positive cosmological constant. As a result, we find that this conjecture has a severe constraint power. Not only does this conjecture rule out those cosmological models disfavored by the anthropic principle, but also it imposes an upper bound 10-60 on the cosmological constant for our own universe, which thus provides an alternative macroscopic perspective for understanding the long-standing cosmological constant problem.

  1. METHOD OF TESTING FOR LEAKS

    DOEpatents

    Creutz, E.C.; McAdams, Wm.A.; Foss, M.H.

    1958-07-22

    A method is described for detecting minute holes In fuel element jackets. The method comprises submerging the jacketed body in an atmosphere of a radioactive gas under pressure, the radioactive emanations from said gas being sufficientiy penetratIng to penetrate the jacket of the jacketed body. After the jacketed body is removed from the radtoactive gas atmosphere, it is exannined for the presence of emanations from radioactive gas which entered the jacketed body through the minute holes. In this manner, the detectton of radioactive emanations is a positive indication that the fuel element is not perfectly sealed.

  2. Magnetic Coulomb phase in the spin ice Ho2Ti2O7.

    PubMed

    Fennell, T; Deen, P P; Wildes, A R; Schmalzl, K; Prabhakaran, D; Boothroyd, A T; Aldus, R J; McMorrow, D F; Bramwell, S T

    2009-10-16

    Spin-ice materials are magnetic substances in which the spin directions map onto hydrogen positions in water ice. Their low-temperature magnetic state has been predicted to be a phase that obeys a Gauss' law and supports magnetic monopole excitations: in short, a Coulomb phase. We used polarized neutron scattering to show that the spin-ice material Ho2Ti2O7 exhibits an almost perfect Coulomb phase. Our result proves the existence of such phases in magnetic materials and strongly supports the magnetic monopole theory of spin ice.

  3. Unconditionally stable WLP-FDTD method for the modeling of electromagnetic wave propagation in gyrotropic materials.

    PubMed

    Li, Zheng-Wei; Xi, Xiao-Li; Zhang, Jin-Sheng; Liu, Jiang-fan

    2015-12-14

    The unconditional stable finite-difference time-domain (FDTD) method based on field expansion with weighted Laguerre polynomials (WLPs) is applied to model electromagnetic wave propagation in gyrotropic materials. The conventional Yee cell is modified to have the tightly coupled current density components located at the same spatial position. The perfectly matched layer (PML) is formulated in a stretched-coordinate (SC) system with the complex-frequency-shifted (CFS) factor to achieve good absorption performance. Numerical examples are shown to validate the accuracy and efficiency of the proposed method.

  4. 16 CFR 23.12 - Misuse of the words “flawless,” “perfect,” etc.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...,” “perfect,” etc. (a) It is unfair or deceptive to use the word “flawless” to describe any diamond that... a person skilled in diamond grading. (b) It is unfair or deceptive to use the word “perfect,” or any representation of similar meaning, to describe any diamond unless the diamond meets the definition of “flawless...

  5. 16 CFR 23.12 - Misuse of the words “flawless,” “perfect,” etc.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...,” “perfect,” etc. (a) It is unfair or deceptive to use the word “flawless” to describe any diamond that... a person skilled in diamond grading. (b) It is unfair or deceptive to use the word “perfect,” or any representation of similar meaning, to describe any diamond unless the diamond meets the definition of “flawless...

  6. 16 CFR 23.12 - Misuse of the words “flawless,” “perfect,” etc.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...,” “perfect,” etc. (a) It is unfair or deceptive to use the word “flawless” to describe any diamond that... a person skilled in diamond grading. (b) It is unfair or deceptive to use the word “perfect,” or any representation of similar meaning, to describe any diamond unless the diamond meets the definition of “flawless...

  7. 16 CFR 23.12 - Misuse of the words “flawless,” “perfect,” etc.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...,” “perfect,” etc. (a) It is unfair or deceptive to use the word “flawless” to describe any diamond that... a person skilled in diamond grading. (b) It is unfair or deceptive to use the word “perfect,” or any representation of similar meaning, to describe any diamond unless the diamond meets the definition of “flawless...

  8. Effect of Coulomb friction on orientational correlation and velocity distribution functions in a sheared dilute granular gas.

    PubMed

    Gayen, Bishakhdatta; Alam, Meheboob

    2011-08-01

    From particle simulations of a sheared frictional granular gas, we show that the Coulomb friction can have dramatic effects on orientational correlation as well as on both the translational and angular velocity distribution functions even in the Boltzmann (dilute) limit. The dependence of orientational correlation on friction coefficient (μ) is found to be nonmonotonic, and the Coulomb friction plays a dual role of enhancing or diminishing the orientational correlation, depending on the value of the tangential restitution coefficient (which characterizes the roughness of particles). From the sticking limit (i.e., with no sliding contact) of rough particles, decreasing the Coulomb friction is found to reduce the density and spatial velocity correlations which, together with diminished orientational correlation for small enough μ, are responsible for the transition from non-gaussian to gaussian distribution functions in the double limit of small friction (μ→0) and nearly elastic particles (e→1). This double limit in fact corresponds to perfectly smooth particles, and hence the maxwellian (gaussian) is indeed a solution of the Boltzmann equation for a frictional granular gas in the limit of elastic collisions and zero Coulomb friction at any roughness. The high-velocity tails of both distribution functions seem to follow stretched exponentials even in the presence of Coulomb friction, and the related velocity exponents deviate strongly from a gaussian with increasing friction.

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mirshafieyan, Seyed Sadreddin; Luk, Ting S.; Guo, Junpeng

    Here, we demonstrated perfect light absorption in optical nanocavities made of ultra-thin percolation aluminum and silicon films deposited on an aluminum surface. The total layer thickness of the aluminum and silicon films is one order of magnitude less than perfect absorption wavelength in the visible spectral range. The ratio of silicon cavity layer thickness to perfect absorption wavelength decreases as wavelength decreases due to the increased phase delays at silicon-aluminum boundaries at shorter wavelengths. It is explained that perfect light absorption is due to critical coupling of incident wave to the fundamental Fabry-Perot resonance mode of the structure where themore » round trip phase delay is zero. Simulations were performed and the results agree well with the measurement results.« less

  10. Coherent Perfect Rotation: The conservative analogue of CPA

    NASA Astrophysics Data System (ADS)

    Crescimanno, Michael; Dawson, Nathan; Andrews, James

    2012-06-01

    The two classes of conservative, linear, optical rotary effects (optical activity and Faraday rotation) are distinguished by their behavior under time reversal. In analogy with coherent perfect absorption (CPA) resonances, where counter-propagating light fields are completely converted into other degrees of freedom, we show that in a linear conservative medium only time-odd (Faraday) rotation is capable of coherent perfect rotation, by which we mean the complete transfer of any arbitrarily oriented polarization of light into the other orthogonal polarization via the application of phased counter-propagating light fields. This contributes to the understanding of the importance of time reversal symmetry in perfect mode conversion that may be of use in optical device design.

  11. Coherent perfect absorber and laser modes in purely imaginary metamaterials

    NASA Astrophysics Data System (ADS)

    Fu, Yangyang; Cao, Yanyan; Cummer, Steven A.; Xu, Yadong; Chen, Huanyang

    2017-10-01

    Conjugate metamaterials, in which the permittivity and the permeability are complex conjugates of each other, possess the elements of loss and gain simultaneously. By employing a conjugate metamaterial with a purely imaginary form, we propose a mechanism for realizing both coherent perfect absorber (CPA) and laser modes. Moreover, the general conditions for obtaining CPA and laser modes, including obtaining them simultaneously, are revealed by analyzing the wave scattering properties of a slab made of purely imaginary metamaterials (PIMs). Specifically, in a PIM slab with a subunity effective refractive index, the CPA mode can be simplified as a perfect absorption mode and the incident wave from one side could be perfectly absorbed.

  12. Boundary terms and three-point functions: an AdS/CFT puzzle resolved

    DOE PAGES

    Freedman, Daniel Z.; Pilch, Krzysztof; Pufu, Silviu S.; ...

    2017-06-12

    N=8 superconformal field theories, such as the ABJM theory at Chern-Simons level k = 1 or 2, contain 35 scalar operators O IJ with Δ = 1 in the 35 v representation of SO(8). The 3-point correlation function of these operators is non-vanishing, and indeed can be calculated non-perturbatively in the field theory. But its AdS 4 gravity dual, obtained from gauged N=8 supergravity, has no cubic A 3 couplings in its Lagrangian, where A IJ is the bulk dual of OIJ. So conventional Witten diagrams cannot furnish the field theory result. We show that the extension of bulk supersymmetrymore » to the AdS 4 boundary requires the introduction of a finite A 3 counterterm that does provide a perfect match to the 3-point correlator. Boundary supersymmetry also requires infinite counterterms which agree with the method of holographic renormalization. The generating functional of correlation functions of the Δ = 1 operators is the Legendre transform of the on-shell action, and the supersymmetry properties of this functional play a significant role in our treatment.« less

  13. Boundary terms and three-point functions: an AdS/CFT puzzle resolved

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Freedman, Daniel Z.; Pilch, Krzysztof; Pufu, Silviu S.

    N=8 superconformal field theories, such as the ABJM theory at Chern-Simons level k = 1 or 2, contain 35 scalar operators O IJ with Δ = 1 in the 35 v representation of SO(8). The 3-point correlation function of these operators is non-vanishing, and indeed can be calculated non-perturbatively in the field theory. But its AdS 4 gravity dual, obtained from gauged N=8 supergravity, has no cubic A 3 couplings in its Lagrangian, where A IJ is the bulk dual of OIJ. So conventional Witten diagrams cannot furnish the field theory result. We show that the extension of bulk supersymmetrymore » to the AdS 4 boundary requires the introduction of a finite A 3 counterterm that does provide a perfect match to the 3-point correlator. Boundary supersymmetry also requires infinite counterterms which agree with the method of holographic renormalization. The generating functional of correlation functions of the Δ = 1 operators is the Legendre transform of the on-shell action, and the supersymmetry properties of this functional play a significant role in our treatment.« less

  14. Relation between perception of vertical axis rotation and vestibulo-ocular reflex symmetry

    NASA Technical Reports Server (NTRS)

    Peterka, Robert J.; Benolken, Martha S.

    1991-01-01

    Subjects seated in a vertical axis rotation chair controlled their rotational velocity by adjusting a potentiometer. Their goal was to null out pseudorandom rotational perturbations in order to remain perceptually stationary. Most subjects showed a slow linear drift of velocity (a constant acceleration) to one side when they were deprived of an earth-fixed visual reference. The amplitude and direction of this drift can be considered a measure of a static bias in the subject's perception of rotation. The presence of a perceptual bias is consistent with a small, constant imbalance of vestibular function which could be of either central or peripheral origin. Deviations from perfect vestibulocular reflex (VOR) symmetry are also assumed to be related to imbalances in either peripheral or central vestibular function. Researchers looked for correlations between perceptual bias and various measures of vestibular reflex symmetry that might suggest a common source for both reflective and perceptual imbalances. No correlations were found. Measurement errors could not account for these results since repeated tests on the same subjects of both perceptual bias and VOR symmetry were well correlated.

  15. In situ fluorescence spectroscopy correlates ionomer degradation to reactive oxygen species generation in an operating fuel cell.

    PubMed

    Prabhakaran, Venkateshkumar; Arges, Christopher G; Ramani, Vijay

    2013-11-21

    The rate of generation of reactive oxygen species (ROS) within the polymer electrolyte membrane (PEM) of an operating proton exchange member fuel cell (PEMFC) was monitored using in situ fluorescence spectroscopy. A modified barrier layer was introduced between the PEM and the electrocatalyst layer to eliminate metal-dye interactions and fluorescence resonance energy transfer (FRET) effects during measurements. Standard fuel cell operating parameters (temperature, relative humidity, and electrode potential) were systematically varied to evaluate their influence on the rate of ROS generation during PEMFC operation. Independently, the macroscopic rate of PEM degradation was measured by monitoring the fluoride ion emission rate (FER) in the effluent stream at each operating condition. The ROS generation reaction rate constant (estimated from the in situ fluorescence experiments) correlated perfectly with the measured FER across all conditions, demonstrating unequivocally for the first time that a direct correlation exists between in situ ROS generation and PEM macroscopic degradation. The activation energy for ROS generation within the PEM was estimated to be 12.5 kJ mol(-1).

  16. Computing Earthquake Probabilities on Global Scales

    NASA Astrophysics Data System (ADS)

    Holliday, James R.; Graves, William R.; Rundle, John B.; Turcotte, Donald L.

    2016-03-01

    Large devastating events in systems such as earthquakes, typhoons, market crashes, electricity grid blackouts, floods, droughts, wars and conflicts, and landslides can be unexpected and devastating. Events in many of these systems display frequency-size statistics that are power laws. Previously, we presented a new method for calculating probabilities for large events in systems such as these. This method counts the number of small events since the last large event and then converts this count into a probability by using a Weibull probability law. We applied this method to the calculation of large earthquake probabilities in California-Nevada, USA. In that study, we considered a fixed geographic region and assumed that all earthquakes within that region, large magnitudes as well as small, were perfectly correlated. In the present article, we extend this model to systems in which the events have a finite correlation length. We modify our previous results by employing the correlation function for near mean field systems having long-range interactions, an example of which is earthquakes and elastic interactions. We then construct an application of the method and show examples of computed earthquake probabilities.

  17. Multiple emitters in a waveguide: Nonreciprocity and correlated photons at perfect elastic transmission

    NASA Astrophysics Data System (ADS)

    Fang, Yao-Lung L.; Baranger, Harold U.

    2017-07-01

    We investigate interference and correlation effects when several detuned emitters are placed along a one-dimensional photonic waveguide. Such a setup allows multiple interactions between the photons and the strongly coupled emitters, and underlies proposed devices for quantum information processing. We show, first, that a pair of detuned two-level systems (2LS) separated by a half wavelength mimic a driven Λ -type three-level system (3LS) in both the single- and two-photon sectors. There is an interference-induced transparency peak at which the fluorescence is quenched, leaving the transmitted photons completely uncorrelated. Slightly away from this separation, we find that the inelastic scattering (fluorescence) is large, leading to nonlinear effects such as nonreciprocity (rectification). We connect this nonreciprocity to inelastic scattering caused by driving a dark pole and so derive a condition for maximum rectification. Finally, by placing a true 3LS midway between the two 2LS, we show that elastic scattering produces only transmission, but inelastic scattering nevertheless occurs (the fluorescence is not quenched) causing substantial photon correlations.

  18. Statistics of a neuron model driven by asymmetric colored noise.

    PubMed

    Müller-Hansen, Finn; Droste, Felix; Lindner, Benjamin

    2015-02-01

    Irregular firing of neurons can be modeled as a stochastic process. Here we study the perfect integrate-and-fire neuron driven by dichotomous noise, a Markovian process that jumps between two states (i.e., possesses a non-Gaussian statistics) and exhibits nonvanishing temporal correlations (i.e., represents a colored noise). Specifically, we consider asymmetric dichotomous noise with two different transition rates. Using a first-passage-time formulation, we derive exact expressions for the probability density and the serial correlation coefficient of the interspike interval (time interval between two subsequent neural action potentials) and the power spectrum of the spike train. Furthermore, we extend the model by including additional Gaussian white noise, and we give approximations for the interspike interval (ISI) statistics in this case. Numerical simulations are used to validate the exact analytical results for pure dichotomous noise, and to test the approximations of the ISI statistics when Gaussian white noise is included. The results may help to understand how correlations and asymmetry of noise and signals in nerve cells shape neuronal firing statistics.

  19. Reprint of : Hanbury-Brown Twiss noise correlation with time controlled quasi-particles in ballistic quantum conductors

    NASA Astrophysics Data System (ADS)

    Glattli, D. C.; Roulleau, P.

    2016-08-01

    We study the Hanbury Brown and Twiss correlation of electronic quasi-particles injected in a quantum conductor using current noise correlations and we experimentally address the effect of finite temperature. By controlling the relative time of injection of two streams of electrons it is possible to probe the fermionic antibunching, performing the electron analog of the optical Hong Ou Mandel (HOM) experiment. The electrons are injected using voltage pulses with either sine-wave or Lorentzian shape. In the latter case, we propose a set of orthogonal wavefunctions, describing periodic trains of multiply charged electron pulses, which give a simple interpretation to the HOM shot noise. The effect of temperature is then discussed and experimentally investigated. We observe a perfect electron anti-bunching for a large range of temperature, showing that, as recently predicted, thermal mixing of the states does not affect anti-bunching properties, a feature qualitatively different from dephasing. For single charge Lorentzian pulses, we provide experimental evidence of the prediction that the HOM shot noise variation versus the emission time delay is remarkably independent of the temperature.

  20. Sample Errors Call Into Question Conclusions Regarding Same-Sex Married Parents: A Comment on "Family Structure and Child Health: Does the Sex Composition of Parents Matter?"

    PubMed

    Paul Sullins, D

    2017-12-01

    Because of classification errors reported by the National Center for Health Statistics, an estimated 42 % of the same-sex married partners in the sample for this study are misclassified different-sex married partners, thus calling into question findings regarding same-sex married parents. Including biological parentage as a control variable suppresses same-sex/different-sex differences, thus obscuring the data error. Parentage is not appropriate as a control because it correlates nearly perfectly (+.97, gamma) with the same-sex/different-sex distinction and is invariant for the category of joint biological parents.

  1. Heating Augmentation Due to Compression Pad Cavities on the Project Orion CEV Heat Shield

    NASA Technical Reports Server (NTRS)

    Hollis, Brian R.

    2009-01-01

    An experimental study has been conducted to assess the effects of compression pad cavities on the aeroheating environment of the Project Orion CEV heat-shield. Testing was conducted in Mach 6 and Mach 10 perfect-gas wind tunnels to obtain heating measurements in and around the compression pads cavities using global phosphor thermography. Data were obtained over a wide range of Reynolds numbers that produced laminar, transitional, and turbulent flow within and downstream of the cavities. The effects of cavity dimensions on boundary-layer transition and heating augmentation levels were studied. Correlations were developed for transition onset and for the average cavity-heating augmentation.

  2. Compression Pad Cavity Heating Augmentation on Orion Heat Shield

    NASA Technical Reports Server (NTRS)

    Hollis, Brian R.

    2011-01-01

    An experimental study has been conducted to assess the effects of compression pad cavities on the aeroheating environment of the Project Orion Crew Exploration Vehicle heat shield. Testing was conducted in Mach 6 and 10 perfect-gas wind tunnels to obtain heating measurements in and around the compression pads cavities using global phosphor thermography. Data were obtained over a wide range of Reynolds numbers that produced laminar, transitional, and turbulent flow within and downstream of the cavities. The effects of cavity dimensions on boundary-layer transition and heating augmentation levels were studied. Correlations were developed for transition onset and for the average cavity-heating augmentation.

  3. Topological strings in d < 1

    NASA Astrophysics Data System (ADS)

    Dijkgraaf, Robbert; Verlinde, Herman; Verlinde, Erik

    1991-03-01

    We calculate correlation functions in minimal topological field theories. These twisted versions of N = 2 minimal models have recently been proposed to describe d < 1 matrix models, once coupled to topological gravity. In our calculation we make use of the Landau-Ginzburg formulation of the N = 2 models, and we find a direct relation between the Landau-Ginzburg superpotential and the KdV differential operator. Using this correspondence we show that the minimal topological models are in perfect agreement with the matrix models as solved in terms of the KdV hierarchy. This proves the equivalence at tree-level of topological and ordinary string thoery in d < 1.

  4. Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs.

    PubMed Central

    Scott, D W; Miller, W H; Cayatte, S M; Bagladi, M S

    1994-01-01

    Tylosin tablets (20 mg/kg, q12h) were administered orally to 21 dogs with superficial or deep staphylococcal pyodermas. Response to therapy was excellent in 90.5% of the dogs, and in vitro susceptibility testing correlated perfectly with therapeutic response. Duration of therapy varied from 17 to 91 days, with an average of 33 days. Relapses occurred in 28.6% of the dogs within a three-month period. No side effects were reported. Under the conditions of the study, tylosin was an effective and safe antibiotic for the treatment of staphylococcal pyoderma in dogs. PMID:7994702

  5. Modelling directional solidification

    NASA Technical Reports Server (NTRS)

    Wilcox, William R.

    1990-01-01

    The long range goal is to develop an improved understanding of phenomena of importance to directional solidification, to enable explanation and prediction of differences in behavior between solidification on Earth and in space. Emphasis during the period of this grant was on experimentally determining the influence of convection and freezing rate fluctuations on compositional homogeneity and crystalline perfection in the vertical Bridgman-Stockbarger technique. Heater temperature profiles, buoyancy-driven convection, and doping inhomogeneties were correlated using naphthalene doped with azulene. In addition the influence of spin-up/spin-down on compositional homogeneity and microstructure of indium gallium antimonide and the effect of imposed melting-freezing cycles on indium gallium antimonide are discussed.

  6. Perfect Circular Dichroism in the Haldane Model

    NASA Astrophysics Data System (ADS)

    Ghalamkari, Kazu; Tatsumi, Yuki; Saito, Riichiro

    2018-06-01

    We theoretically show that perfect circular dichroism (CD) occurs in the Haldane model in which the two-dimensional (2D) material absorbs only either left-handed or right-handed circularly polarized light. Perfect CD occurs in the phase diagram of the Haldane model when the zero-field quantum Hall conductivity has a nonzero value. The coincidence of the occurrence of perfect CD and zero-field quantum Hall effect is attributed to the fact that the effect of broken time-reversal symmetry is larger than the effect of broken inversion symmetry. On the other hand, valley polarization and perfect CD occur exclusively in the phase diagram. Further, for the four regions of the phase diagram, pseudospin polarization occurs at the K and K' points in the hexagonal Brillouin zone with either the same sign or opposite sign for the K and K' points and for the valence and conduction bands. This theoretical prediction may have an impact on search for a new optical device that selects circularly polarized light controlled by the electric field.

  7. Perfect fluid Lagrangian and its cosmological implications in theories of gravity with nonminimally coupled matter fields

    NASA Astrophysics Data System (ADS)

    Avelino, P. P.; Azevedo, R. P. L.

    2018-03-01

    In this paper we show that the on-shell Lagrangian of a perfect fluid depends on microscopic properties of the fluid, giving specific examples of perfect fluids with different on-shell Lagrangians but with the same energy-momentum tensor. We demonstrate that if the fluid is constituted by localized concentrations of energy with fixed rest mass and structure (solitons) then the average on-shell Lagrangian of a perfect fluid is given by Lm=T , where T is the trace of the energy-momentum tensor. We show that our results have profound implications for theories of gravity where the matter Lagrangian appears explicitly in the equations of motion of the gravitational and matter fields, potentially leading to observable deviations from a nearly perfect cosmic microwave background black body spectrum: n -type spectral distortions, affecting the normalization of the spectral energy density. Finally, we put stringent constraints on f (R ,Lm) theories of gravity using the COBE-FIRAS measurement of the spectral radiance of the cosmic microwave background.

  8. The perils of the imperfect expectation of the perfect baby.

    PubMed

    Chervenak, Frank A; McCullough, Laurence B; Brent, Robert L

    2010-08-01

    Advances in modern medicine invite the assumption that medicine can control human biology. There is a perilous logic that leads from expectations of medicine's control over reproductive biology to the expectation of having a perfect baby. This article proposes that obstetricians should take a preventive ethics approach to the care of pregnant women with expectations for a perfect baby. We use Nathaniel Hawthorne's classic short story, "The Birthmark," to illustrate the perils of the logic of control and perfection through science and then identify possible contemporary sources of the expectation of the perfect baby. We propose that the informed consent process should be used as a preventive ethics tool throughout the course of pregnancy to educate pregnant women about the inherent errors of human reproduction, the highly variable clinical outcomes of these errors, the limited capacity of medicine to detect these errors, and the even more limited capacity to correct them. Copyright (c) 2010 Mosby, Inc. All rights reserved.

  9. A hybrid of monopoly and perfect competition model for hi-tech products

    NASA Astrophysics Data System (ADS)

    Yang, P. C.; Wee, H. M.; Pai, S.; Yang, H. J.; Wee, P. K. P.

    2010-11-01

    For Hi-tech products, the demand rate, the component cost as well as the selling price usually decline significantly with time. In the case of perfect competition, shortages usually result in lost sales; while in a monopoly, shortages will be completely backordered. However, neither perfect competition nor monopoly exists. Therefore, there is a need to develop a replenishment model considering a hybrid of perfect competition and monopoly when the cost, price and demand are decreasing simultaneously. A numerical example and sensitivity analysis are carried out to illustrate this model. The results show that a higher decline-rate in the component cost leads to a smaller service level and a larger replenishment interval. When the component cost decline rate increases and the selling price decline rate decreases simultaneously, the replenishment interval decreases. In perfect competition it is better to have a high service level, while for the case with monopoly, keeping a low service level is better due to complete backordering.

  10. Strong coupling of plasmon and nanocavity modes for dual-band, near-perfect absorbers and ultrathin photovoltaics

    DOE PAGES

    Hagglund, Carl; Zeltzer, Gabriel; Ruiz, Ricardo; ...

    2016-01-29

    In this study, when optical resonances interact strongly, hybridized modes are formed with mixed properties inherited from the basic modes. Strong coupling therefore tends to equalize properties such as damping and oscillator strength of the spectrally separate resonance modes. This effect is here shown to be very useful for the realization of near-perfect dual-band absorption with ultrathin (~10 nm) layers in a simple geometry. Absorber layers are constructed by atomic layer deposition of the heavy-damping semiconductor tin monosulfide (SnS) onto a two-dimensional gold nanodot array. In combination with a thin (55 nm) SiO 2 spacer layer and a highly reflectivemore » Al film on the back, a semiopen nanocavity is formed. The SnS-coated array supports a localized surface plasmon resonance in the vicinity of the lowest order antisymmetric Fabry–Perot resonance of the nanocavity. Very strong coupling of the two resonances is evident through anticrossing behavior with a minimum peak splitting of 400 meV, amounting to 24% of the plasmon resonance energy. The mode equalization resulting from this strong interaction enables simultaneous optical impedance matching of the system at both resonances and thereby two near-perfect absorption peaks, which together cover a broad spectral range. When paired with the heavy damping from SnS band-to-band transitions, this further enables approximately 60% of normal incident solar photons with energies exceeding the band gap to be absorbed in the 10 nm SnS coating. Thereby, these results establish a distinct relevance of strong coupling phenomena to efficient, nanoscale photovoltaic absorbers and more generally for fulfilling a specific optical condition at multiple spectral positions.« less

  11. Zeroth Poisson Homology, Foliated Cohomology and Perfect Poisson Manifolds

    NASA Astrophysics Data System (ADS)

    Martínez-Torres, David; Miranda, Eva

    2018-01-01

    We prove that, for compact regular Poisson manifolds, the zeroth homology group is isomorphic to the top foliated cohomology group, and we give some applications. In particular, we show that, for regular unimodular Poisson manifolds, top Poisson and foliated cohomology groups are isomorphic. Inspired by the symplectic setting, we define what a perfect Poisson manifold is. We use these Poisson homology computations to provide families of perfect Poisson manifolds.

  12. Developments in Coherent Perfect Polarization Rotation

    NASA Astrophysics Data System (ADS)

    Crescimanno, Michael; Andrews, James; Zhou, Chaunhong; Baker, Michael

    2015-05-01

    Coherent Perfect Polarization Rotation (CPR) is a useful technique akin to Coherent Perfect Absorption (CPA, also known as the anti-laser) but that results in very high efficiency optical mode conversion. We describe the analysis of recent experimental data from our CPR testbed, the use of CPR in miniaturizing optical isolators and CPR phenomena in non-linear optics. Work supported by the N.S.F. under Grant No. ECCS-1360725.

  13. 16 CFR 23.12 - Misuse of the words “flawless,” “perfect,” etc.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Misuse of the words âflawless,â âperfect,â... GUIDES FOR THE JEWELRY, PRECIOUS METALS, AND PEWTER INDUSTRIES § 23.12 Misuse of the words “flawless,” “perfect,” etc. (a) It is unfair or deceptive to use the word “flawless” to describe any diamond that...

  14. 16 CFR 23.26 - Misuse of the words “flawless,” “perfect,” etc.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Misuse of the words âflawless,â âperfect,â... GUIDES FOR THE JEWELRY, PRECIOUS METALS, AND PEWTER INDUSTRIES § 23.26 Misuse of the words “flawless,” “perfect,” etc. (a) It is unfair or deceptive to use the word “flawless” as a quality description of any...

  15. Perfect and broadband acoustic absorption by critically coupled sub-wavelength resonators.

    PubMed

    Romero-García, V; Theocharis, G; Richoux, O; Merkel, A; Tournat, V; Pagneux, V

    2016-01-19

    Perfect absorption is an interdisciplinary topic with a large number of applications, the challenge of which consists of broadening its inherently narrow frequency-band performance. We experimentally and analytically report perfect and broadband absorption for audible sound, by the mechanism of critical coupling, with a sub-wavelength multi-resonant scatterer (SMRS) made of a plate-resonator/closed waveguide structure. In order to introduce the role of the key parameters, we first present the case of a single resonant scatterer (SRS) made of a Helmholtz resonator/closed waveguide structure. In both cases the controlled balance between the energy leakage of the several resonances and the inherent losses of the system leads to perfect absorption peaks. In the case of the SMRS we show that systems with large inherent losses can be critically coupled using resonances with large leakage. In particular, we show that in the SMRS system, with a thickness of λ/12 and diameter of λ/7, several perfect absorption peaks overlap to produce absorption bigger than 93% for frequencies that extend over a factor of 2 in audible frequencies. The reported concepts and methodology provide guidelines for the design of broadband perfect absorbers which could contribute to solve the major issue of noise reduction.

  16. Perfect and broadband acoustic absorption by critically coupled sub-wavelength resonators

    NASA Astrophysics Data System (ADS)

    Romero-García, V.; Theocharis, G.; Richoux, O.; Merkel, A.; Tournat, V.; Pagneux, V.

    2016-01-01

    Perfect absorption is an interdisciplinary topic with a large number of applications, the challenge of which consists of broadening its inherently narrow frequency-band performance. We experimentally and analytically report perfect and broadband absorption for audible sound, by the mechanism of critical coupling, with a sub-wavelength multi-resonant scatterer (SMRS) made of a plate-resonator/closed waveguide structure. In order to introduce the role of the key parameters, we first present the case of a single resonant scatterer (SRS) made of a Helmholtz resonator/closed waveguide structure. In both cases the controlled balance between the energy leakage of the several resonances and the inherent losses of the system leads to perfect absorption peaks. In the case of the SMRS we show that systems with large inherent losses can be critically coupled using resonances with large leakage. In particular, we show that in the SMRS system, with a thickness of λ/12 and diameter of λ/7, several perfect absorption peaks overlap to produce absorption bigger than 93% for frequencies that extend over a factor of 2 in audible frequencies. The reported concepts and methodology provide guidelines for the design of broadband perfect absorbers which could contribute to solve the major issue of noise reduction.

  17. Perfect and broadband acoustic absorption by critically coupled sub-wavelength resonators

    PubMed Central

    Romero-García, V.; Theocharis, G.; Richoux, O.; Merkel, A.; Tournat, V.; Pagneux, V.

    2016-01-01

    Perfect absorption is an interdisciplinary topic with a large number of applications, the challenge of which consists of broadening its inherently narrow frequency-band performance. We experimentally and analytically report perfect and broadband absorption for audible sound, by the mechanism of critical coupling, with a sub-wavelength multi-resonant scatterer (SMRS) made of a plate-resonator/closed waveguide structure. In order to introduce the role of the key parameters, we first present the case of a single resonant scatterer (SRS) made of a Helmholtz resonator/closed waveguide structure. In both cases the controlled balance between the energy leakage of the several resonances and the inherent losses of the system leads to perfect absorption peaks. In the case of the SMRS we show that systems with large inherent losses can be critically coupled using resonances with large leakage. In particular, we show that in the SMRS system, with a thickness of λ/12 and diameter of λ/7, several perfect absorption peaks overlap to produce absorption bigger than 93% for frequencies that extend over a factor of 2 in audible frequencies. The reported concepts and methodology provide guidelines for the design of broadband perfect absorbers which could contribute to solve the major issue of noise reduction. PMID:26781863

  18. Narrow band perfect absorber for maximum localized magnetic and electric field enhancement and sensing applications

    PubMed Central

    Yong, Zhengdong; Zhang, Senlin; Gong, Chensheng; He, Sailing

    2016-01-01

    Plasmonics offer an exciting way to mediate the interaction between light and matter, allowing strong field enhancement and confinement, large absorption and scattering at resonance. However, simultaneous realization of ultra-narrow band perfect absorption and electromagnetic field enhancement is challenging due to the intrinsic high optical losses and radiative damping in metals. Here, we propose an all-metal plasmonic absorber with an absorption bandwidth less than 8 nm and polarization insensitive absorptivity exceeding 99%. Unlike traditional Metal-Dielectric-Metal configurations, we demonstrate that the narrowband perfect absorption and field enhancement are ascribed to the vertical gap plasmonic mode in the deep subwavelength scale, which has a high quality factor of 120 and mode volume of about 10−4 × (λres/n)3. Based on the coupled mode theory, we verify that the diluted field enhancement is proportional to the absorption, and thus perfect absorption is critical to maximum field enhancement. In addition, the proposed perfect absorber can be operated as a refractive index sensor with a sensitivity of 885 nm/RIU and figure of merit as high as 110. It provides a new design strategy for narrow band perfect absorption and local field enhancement, and has potential applications in biosensors, filters and nonlinear optics. PMID:27046540

  19. Artificial perfect electric conductor-perfect magnetic conductor anisotropic metasurface for generating orbital angular momentum of microwave with nearly perfect conversion efficiency

    NASA Astrophysics Data System (ADS)

    Chen, Menglin L. N.; Jiang, Li Jun; Sha, Wei E. I.

    2016-02-01

    Orbital angular momentum (OAM) is a promising degree of freedom for fundamental studies in electromagnetics and quantum mechanics. The unlimited state space of OAM shows a great potential to enhance channel capacities of classical and quantum communications. By exploring the Pancharatnam-Berry phase concept and engineering anisotropic scatterers in a metasurface with spatially varying orientations, a plane wave with zero OAM can be converted to a vortex beam carrying nonzero OAM. In this paper, we proposed two types of novel perfect electric conductor-perfect magnetic conductor anisotropic metasurfaces. One is composed of azimuthally continuous loops and the other is constructed by azimuthally discontinuous dipole scatterers. Both types of metasurfaces are mounted on a mushroom-type high impedance surface. Compared to previous metasurface designs for generating OAM, the proposed ones achieve nearly perfect conversion efficiency. In view of the eliminated vertical component of electric field, the continuous metasurface shows very smooth phase pattern at the near-field region, which cannot be achieved by convectional metasurfaces composed of discrete scatterers. On the other hand, the metasurface with discrete dipole scatterers shows a great flexibility to generate OAM with arbitrary topological charges. Our work is fundamentally and practically important to high-performance OAM generation.

  20. [Reliable microbiological diagnosis of vulvovaginal candidiasis].

    PubMed

    Baykushev, R; Ouzounova-Raykova, V; Stoykova, V; Mitov, I

    2014-01-01

    Vulvovaginal candidiasis is common infection among those affecting the vulva and vagina. Is caused by the perpesentatives from the genus Candida, in most cases C. albicans (85-90%). An increase in the percentage of the so-called non-albicans agents is seen and these pathgogens are often resistant to the most commonly used in the practice antifungals. Faulty diagnosis, incorrect use of azoles, and self-treatment lead to selection of resistant strains and recurrent infections. Identification of Candida species associated with vulvovaginal candidiasis by conventional and PCR techniques. For six months a total number of 213 vaginal secretions were tested applying Gram stain and cultivation on ChromAgar. API Candida fermentation tests and API 20CAUX assimilation tests were performed for the identification of the bacteria. Extraction of DNA of all the smears with subsequent PCR detection of different Candida species were done. 80.7% materials showed presence of blastospores and/or hyphae. Positive culture results were detected in 60 (28.2%) samples. The species specific identification revealed presence of C. albicans in 51 (85%) smears, C. glabrata--in 8 (13.3%), C. krusei--in 2 (3.3%), and S. cervisie--in 1 (2.1%). The PCR technique confirmed the results of the conventional methods. It is worth to mention that 51 of the tested smears were positive for G. vaginalis using additional PCR. The correct diagnosis of the cause of vulvovaginal candidiasis helps in the correct choice of appropriate antifungal therapy and prevents development of recurrent infections and consequences. The PCR based method is rapid, specific and sensitive. It perfectly correlates with the results from the conventional diagnostic tests so it could be selected as a method of choice for the diagnosis of vulvovaginal candidiasis.

  1. The major influence of the atmosphere on intracranial pressure: an observational study.

    PubMed

    Herbowski, Leszek

    2017-01-01

    The impact of the atmosphere on human physiology has been studied widely within the last years. In practice, intracranial pressure is a pressure difference between intracranial compartments and the surrounding atmosphere. This means that gauge intracranial pressure uses atmospheric pressure as its zero point, and therefore, this method of pressure measurement excludes the effects of barometric pressure's fluctuation. The comparison of these two physical quantities can only take place through their absolute value relationship. The aim of this study is to investigate the direct effect of barometric pressure on the absolute intracranial pressure homeostasis. A prospective observational cross-sectional open study was conducted in Szczecin, Poland. In 28 neurosurgical patients with suspected normal-pressure hydrocephalus, intracranial intraventricular pressure was monitored in a sitting position. A total of 168 intracranial pressure and atmospheric pressure measurements were performed. Absolute atmospheric pressure was recorded directly. All values of intracranial gauge pressure were converted to absolute pressure (the sum of gauge intracranial pressure and local absolute atmospheric pressure). The average absolute mean intracranial pressure in the patients is 1006.6 hPa (95 % CI 1004.5 to 1008.8 hPa, SEM 1.1), and the mean absolute atmospheric pressure is 1007.9 hPa (95 % CI 1006.3 to 1009.6 hPa, SEM 0.8). The observed association between atmospheric and intracranial pressure is strongly significant (Spearman correlation r = 0.87, p < 0.05) and all the measurements are perfectly reliable (Bland-Altman coefficient is 4.8 %). It appears from this study that changes in absolute intracranial pressure are related to seasonal variation. Absolute intracranial pressure is shown to be impacted positively by atmospheric pressure.

  2. Fixed-flexion knee radiography using a new positioning device produced highly repeatable measurements of joint space width: ELSA-Brasil Musculoskeletal Study (ELSA-Brasil MSK).

    PubMed

    Telles, Rosa Weiss; Costa-Silva, Luciana; Machado, Luciana A C; Reis, Rodrigo Citton Padilha Dos; Barreto, Sandhi Maria

    To describe the performance of a non-fluoroscopic fixed-flexion PA radiographic protocol with a new positioning device, developed for the assessment of knee osteoarthritis (OA) in Brazilian Longitudinal Study of Adult Health Musculoskeletal Study (ELSA-Brasil MSK). A test-retest design including 19 adults (38 knee images) was conducted. Feasibility of the radiographic protocol was assessed by image quality parameters and presence of radioanatomic alignment according to intermargin distance (IMD) values. Repeatability was assessed for IMD and joint space width (JSW) measured at three different locations. Approximately 90% of knee images presented excellent quality. Frequencies of nearly perfect radioanatomic alignment (IMD ≤1mm) ranged from 29% to 50%, and satisfactory alignment was found in up to 71% and 76% of the images (IMD ≤1.5mm and ≤1.7mm, respectively). Repeatability analyses yielded the following results: IMD [SD of mean difference=1.08; coefficient of variation (%CV)=54.68%; intraclass correlation coefficient (ICC) (95%CI)=0.59 (0.34-0.77)]; JSW [SD of mean difference=0.34-0.61; %CV=4.48%-9.80%; ICC (95%CI)=0.74 (0.55-0.85)-0.94 (0.87-0.97)]. Adequately reproducible measurements of IMD and JSW were found in 68% and 87% of the images, respectively. Despite the difficulty in achieving consistent radioanatomic alignment between subsequent radiographs in terms of IMD, the protocol produced highly repeatable JSW measurements when these were taken at midpoint and 10mm from the medial extremity of the medial tibial plateau. Therefore, measurements of JSW at these locations can be considered adequate for the assessment of knee OA in ELSA-Brasil MSK. Copyright © 2016. Published by Elsevier Editora Ltda.

  3. The major influence of the atmosphere on intracranial pressure: an observational study

    NASA Astrophysics Data System (ADS)

    Herbowski, Leszek

    2017-01-01

    The impact of the atmosphere on human physiology has been studied widely within the last years. In practice, intracranial pressure is a pressure difference between intracranial compartments and the surrounding atmosphere. This means that gauge intracranial pressure uses atmospheric pressure as its zero point, and therefore, this method of pressure measurement excludes the effects of barometric pressure's fluctuation. The comparison of these two physical quantities can only take place through their absolute value relationship. The aim of this study is to investigate the direct effect of barometric pressure on the absolute intracranial pressure homeostasis. A prospective observational cross-sectional open study was conducted in Szczecin, Poland. In 28 neurosurgical patients with suspected normal-pressure hydrocephalus, intracranial intraventricular pressure was monitored in a sitting position. A total of 168 intracranial pressure and atmospheric pressure measurements were performed. Absolute atmospheric pressure was recorded directly. All values of intracranial gauge pressure were converted to absolute pressure (the sum of gauge intracranial pressure and local absolute atmospheric pressure). The average absolute mean intracranial pressure in the patients is 1006.6 hPa (95 % CI 1004.5 to 1008.8 hPa, SEM 1.1), and the mean absolute atmospheric pressure is 1007.9 hPa (95 % CI 1006.3 to 1009.6 hPa, SEM 0.8). The observed association between atmospheric and intracranial pressure is strongly significant (Spearman correlation r = 0.87, p < 0.05) and all the measurements are perfectly reliable (Bland-Altman coefficient is 4.8 %). It appears from this study that changes in absolute intracranial pressure are related to seasonal variation. Absolute intracranial pressure is shown to be impacted positively by atmospheric pressure.

  4. Positioning the library at the epicenter of the networked biomedical enterprise.

    PubMed

    Stead, W W

    1998-01-01

    The changing economic environment in which our biomedical enterprises operate presents unparalleled opportunities to the profession of medical librarianship. Evidence-based medicine, patient empowerment, asynchronous learning networks, and research colaboratories each involve a new type of shared information, or access to information in new ways or by different people. These tasks are ones with which librarianship is directly involved. Librarians are therefore placed perfectly to provide new products and services. To position the library at the epicenter of the networked biomedical enterprise we must meet three challenges: We must align the library's business strategy with that of the larger enterprise. We must provide services in ways that will scale-up to enable new business strategies. We must measure the effectiveness of services in ways that document their role in supporting the enterprise.

  5. A simulator study on information requirements for precision hovering

    NASA Technical Reports Server (NTRS)

    Lemons, J. L.; Dukes, T. A.

    1975-01-01

    A fixed base simulator study of an advanced helicopter instrument display utilizing translational acceleration, velocity and position information is reported. The simulation involved piloting a heavy helicopter using the Integrated Trajectory Error Display (ITED) in a precision hover task. The test series explored two basic areas. The effect on hover accuracy of adding acceleration information was of primary concern. Also of interest was the operators' ability to use degraded information derived from less sophisticated sources. The addition of translational acceleration to a display containing velocity and position information did not appear to improve the hover performance significantly. However, displayed acceleration information seemed to increase the damping of the man machine system. Finally, the pilots could use translational information synthesized from attitude and angular acceleration as effectively as perfect acceleration.

  6. Target and orbit feedback simulations of a muSR beam line at BNL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MacKay, W.; Blaskiewicz, M.; Fischer, W.

    Well-polarized positive surface muons are a tool to measure the magnetic properties of materials since the precession rate of the spin can be determined from the observation of the positron directions when the muons decay. For a dc beam an ideal µSR flux for surface µ + should be about 40 kHz/mm 2. In this report we show how this flux could be achieved in a beam line using the AGS complex at BNL for a source of protons. We also determined that an orbit feedback system with a pair of thin silicon position monitors and kickers would miss themore » desired flux by at least an order of magnitude, even with perfect time resolution and no multiple scattering.« less

  7. Faceting, composition and crystal phase evolution in III-V antimonide nanowire heterostructures revealed by combining microscopy techniques.

    PubMed

    Xu, Tao; Dick, Kimberly A; Plissard, Sébastien; Nguyen, Thanh Hai; Makoudi, Younes; Berthe, Maxime; Nys, Jean-Philippe; Wallart, Xavier; Grandidier, Bruno; Caroff, Philippe

    2012-03-09

    III-V antimonide nanowires are among the most interesting semiconductors for transport physics, nanoelectronics and long-wavelength optoelectronic devices due to their optimal material properties. In order to investigate their complex crystal structure evolution, faceting and composition, we report a combined scanning electron microscopy (SEM), transmission electron microscopy (TEM), and scanning tunneling microscopy (STM) study of gold-nucleated ternary InAs/InAs(1-x)Sb(x) nanowire heterostructures grown by molecular beam epitaxy. SEM showed the general morphology and faceting, TEM revealed the internal crystal structure and ternary compositions, while STM was successfully applied to characterize the oxide-free nanowire sidewalls, in terms of nanofaceting morphology, atomic structure and surface composition. The complementary use of these techniques allows for correlation of the morphological and structural properties of the nanowires with the amount of Sb incorporated during growth. The addition of even a minute amount of Sb to InAs changes the crystal structure from perfect wurtzite to perfect zinc blende, via intermediate stacking fault and pseudo-periodic twinning regimes. Moreover, the addition of Sb during the axial growth of InAs/InAs(1-x)Sb(x) heterostructure nanowires causes a significant conformal lateral overgrowth on both segments, leading to the spontaneous formation of a core-shell structure, with an Sb-rich shell.

  8. Team decision problems with classical and quantum signals

    PubMed Central

    Brandenburger, Adam; La Mura, Pierfrancesco

    2016-01-01

    We study team decision problems where communication is not possible, but coordination among team members can be realized via signals in a shared environment. We consider a variety of decision problems that differ in what team members know about one another's actions and knowledge. For each type of decision problem, we investigate how different assumptions on the available signals affect team performance. Specifically, we consider the cases of perfectly correlated, i.i.d., and exchangeable classical signals, as well as the case of quantum signals. We find that, whereas in perfect-recall trees (Kuhn 1950 Proc. Natl Acad. Sci. USA 36, 570–576; Kuhn 1953 In Contributions to the theory of games, vol. II (eds H Kuhn, A Tucker), pp. 193–216) no type of signal improves performance, in imperfect-recall trees quantum signals may bring an improvement. Isbell (Isbell 1957 In Contributions to the theory of games, vol. III (eds M Drescher, A Tucker, P Wolfe), pp. 79–96) proved that, in non-Kuhn trees, classical i.i.d. signals may improve performance. We show that further improvement may be possible by use of classical exchangeable or quantum signals. We include an example of the effect of quantum signals in the context of high-frequency trading. PMID:26621985

  9. Team decision problems with classical and quantum signals.

    PubMed

    Brandenburger, Adam; La Mura, Pierfrancesco

    2016-01-13

    We study team decision problems where communication is not possible, but coordination among team members can be realized via signals in a shared environment. We consider a variety of decision problems that differ in what team members know about one another's actions and knowledge. For each type of decision problem, we investigate how different assumptions on the available signals affect team performance. Specifically, we consider the cases of perfectly correlated, i.i.d., and exchangeable classical signals, as well as the case of quantum signals. We find that, whereas in perfect-recall trees (Kuhn 1950 Proc. Natl Acad. Sci. USA 36, 570-576; Kuhn 1953 In Contributions to the theory of games, vol. II (eds H Kuhn, A Tucker), pp. 193-216) no type of signal improves performance, in imperfect-recall trees quantum signals may bring an improvement. Isbell (Isbell 1957 In Contributions to the theory of games, vol. III (eds M Drescher, A Tucker, P Wolfe), pp. 79-96) proved that, in non-Kuhn trees, classical i.i.d. signals may improve performance. We show that further improvement may be possible by use of classical exchangeable or quantum signals. We include an example of the effect of quantum signals in the context of high-frequency trading. © 2015 The Authors.

  10. Exploratory Bifactor Analysis: The Schmid-Leiman Orthogonalization and Jennrich-Bentler Analytic Rotations

    PubMed Central

    Mansolf, Maxwell; Reise, Steven P.

    2017-01-01

    Analytic bifactor rotations (Jennrich & Bentler, 2011, 2012) have been recently developed and made generally available, but are not well understood. The Jennrich-Bentler analytic bifactor rotations (bi-quartimin and bi-geomin) are an alternative to, and arguably an improvement upon, the less technically sophisticated Schmid-Leiman orthogonalization (Schmid & Leiman, 1957). We review the technical details that underlie the Schmid-Leiman and Jennrich-Bentler bifactor rotations, using simulated data structures to illustrate important features and limitations. For the Schmid-Leiman, we review the problem of inaccurate parameter estimates caused by the linear dependencies, sometimes called “proportionality constraints,” that are required to expand a p correlated factors solution into a (p+1) (bi)factor space. We also review the complexities involved when the data depart from perfect cluster structure (e.g., item cross-loading on group factors). For the Jennrich-Bentler rotations, we describe problems in parameter estimation caused by departures from perfect cluster structure. In addition, we illustrate the related problems of: (a) solutions that are not invariant under different starting values (i.e., local minima problems); and, (b) group factors collapsing onto the general factor. Recommendations are made for substantive researchers including examining all local minima and applying multiple exploratory techniques in an effort to identify an accurate model. PMID:27612521

  11. Conservative Sample Size Determination for Repeated Measures Analysis of Covariance.

    PubMed

    Morgan, Timothy M; Case, L Douglas

    2013-07-05

    In the design of a randomized clinical trial with one pre and multiple post randomized assessments of the outcome variable, one needs to account for the repeated measures in determining the appropriate sample size. Unfortunately, one seldom has a good estimate of the variance of the outcome measure, let alone the correlations among the measurements over time. We show how sample sizes can be calculated by making conservative assumptions regarding the correlations for a variety of covariance structures. The most conservative choice for the correlation depends on the covariance structure and the number of repeated measures. In the absence of good estimates of the correlations, the sample size is often based on a two-sample t-test, making the 'ultra' conservative and unrealistic assumption that there are zero correlations between the baseline and follow-up measures while at the same time assuming there are perfect correlations between the follow-up measures. Compared to the case of taking a single measurement, substantial savings in sample size can be realized by accounting for the repeated measures, even with very conservative assumptions regarding the parameters of the assumed correlation matrix. Assuming compound symmetry, the sample size from the two-sample t-test calculation can be reduced at least 44%, 56%, and 61% for repeated measures analysis of covariance by taking 2, 3, and 4 follow-up measures, respectively. The results offer a rational basis for determining a fairly conservative, yet efficient, sample size for clinical trials with repeated measures and a baseline value.

  12. [The relationship between Cognitive Emotion Regulation Questionnaire (CERQ) and depression, anxiety: Meta-analysis].

    PubMed

    Sakakibara, Ryota; Kitahara, Mizuho

    2016-06-01

    This study aimed to investigate the relations between CERQ and depression, and anxiety and also aimed to reveal the characteristics of a Japanese sample through meta-analysis. The results showed that self-blame, acceptance, rumination, catastrophizing, and blaming others had significantly positive correlations with both depression and anxiety, whereas positive refocusing, refocus on planning, positive reappraisal, and putting into perspective had significantly negative correlations with both variables. Moreover, when comparing the correlation coefficients of the Japanese samples and the combined value, correlations between depression and positive reappraisal were significantly larger than the combined value. On the other hand, regarding the correlation coefficients of depression and putting into perspective, the combined value was larger than the value of Japanese samples. In addition, compared to the combined value, the Japanese sample's positive correlation between anxiety and rumination, and negative correlation between anxiety and positive reappraisal were larger.

  13. Inhibition of coxsackievirus B3 replication by small interfering RNAs requires perfect sequence match in the central region of the viral positive strand.

    PubMed

    Yuan, Ji; Cheung, Paul K M; Zhang, Huifang M; Chau, David; Yang, Decheng

    2005-02-01

    Coxsackievirus B3 (CVB3) is the most common causal agent of viral myocarditis, but existing drug therapies are of limited value. Application of small interfering RNA (siRNA) in knockdown of gene expression is an emerging technology in antiviral gene therapy. To investigate whether RNA interference (RNAi) can protect against CVB3 infection, we evaluated the effects of RNAi on viral replication in HeLa cells and murine cardiomyocytes by using five CVB3-specific siRNAs targeting distinct regions of the viral genome. The most effective one is siRNA-4, targeting the viral protease 2A, achieving a 92% inhibition of CVB3 replication. The specific RNAi effects could last at least 48 h, and cell viability assay revealed that 90% of siRNA-4-pretreated cells were still alive and lacked detectable viral protein expression 48 h postinfection. Moreover, administration of siRNAs after viral infection could also effectively inhibit viral replication, indicating its therapeutic potential. Further evaluation by combination found that no enhanced inhibitory effects were observed when siRNA-4 was cotransfected with each of the other four candidates. In mutational analysis of the mechanisms of siRNA action, we found that siRNA functions by targeting the positive strand of virus and requires a perfect sequence match in the central region of the target, but mismatches were more tolerated near the 3' end than the 5' end of the antisense strand. These findings reveal an effective target for CVB3 silencing and provide a new possibility for antiviral intervention.

  14. Food Safety Knowledge, Attitudes and Behavior among Dairy Plant Workers in Beijing, Northern China.

    PubMed

    Chen, Yan; Ji, Hua; Chen, Li-Jun; Jiang, Rong; Wu, Yong-Ning

    2018-01-03

    The safety of milk and dairy products has always been one of the focuses of consumers, the food industry and regulatory agencies. The purpose of this study was to gain insight into the food safety knowledge, attitudes and behavior of dairy plant workers. A cross-sectional survey was performed between May and August 2015 in three dairy plants in Beijing, northern China. A total of 194 dairy plant workers were interviewed to collect information on food safety knowledge, attitudes and self-reported behavior. The 194 dairy plant workers interviewed showed a sufficient level of knowledge (mean score 34 on a scale from 0-58), perfect attitudes (mean score 17 on a scale from 0-18), and perfect behavior (mean score 38 on a scale from 8-40). Only 39% of workers correctly determined specific pathogens or diseases that could be conveyed through milk and dairy products. 24% of workers knew the correct method of washing hands. A significant positive association was observed between attitudes and knowledge ( p < 0.001) as well as behavior ( p < 0.01). Education level was positively and significantly associated with food safety knowledge, attitudes, and behavior ( p < 0.05). Workers in dairy enterprises in northern China have relatively low levels of knowledge, yet satisfactory attitudes and behavior. The knowledge of microbial food hazards and hand hygiene remains an issue that needs to be emphasized in future training programs. Education level is a determinant of attitudes and behavior with regard to the proper handling of milk and dairy products.

  15. Food Safety Knowledge, Attitudes and Behavior among Dairy Plant Workers in Beijing, Northern China

    PubMed Central

    Ji, Hua; Chen, Li-Jun; Jiang, Rong; Wu, Yong-Ning

    2018-01-01

    The safety of milk and dairy products has always been one of the focuses of consumers, the food industry and regulatory agencies. The purpose of this study was to gain insight into the food safety knowledge, attitudes and behavior of dairy plant workers. A cross-sectional survey was performed between May and August 2015 in three dairy plants in Beijing, northern China. A total of 194 dairy plant workers were interviewed to collect information on food safety knowledge, attitudes and self-reported behavior. The 194 dairy plant workers interviewed showed a sufficient level of knowledge (mean score 34 on a scale from 0–58), perfect attitudes (mean score 17 on a scale from 0–18), and perfect behavior (mean score 38 on a scale from 8–40). Only 39% of workers correctly determined specific pathogens or diseases that could be conveyed through milk and dairy products. 24% of workers knew the correct method of washing hands. A significant positive association was observed between attitudes and knowledge (p < 0.001) as well as behavior (p < 0.01). Education level was positively and significantly associated with food safety knowledge, attitudes, and behavior (p < 0.05). Workers in dairy enterprises in northern China have relatively low levels of knowledge, yet satisfactory attitudes and behavior. The knowledge of microbial food hazards and hand hygiene remains an issue that needs to be emphasized in future training programs. Education level is a determinant of attitudes and behavior with regard to the proper handling of milk and dairy products. PMID:29301381

  16. Coupled-oscillator theory of dispersion and Casimir-Polder interactions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Berman, P. R.; Ford, G. W.; Milonni, P. W.

    2014-10-28

    We address the question of the applicability of the argument theorem (of complex variable theory) to the calculation of two distinct energies: (i) the first-order dispersion interaction energy of two separated oscillators, when one of the oscillators is excited initially and (ii) the Casimir-Polder interaction of a ground-state quantum oscillator near a perfectly conducting plane. We show that the argument theorem can be used to obtain the generally accepted equation for the first-order dispersion interaction energy, which is oscillatory and varies as the inverse power of the separation r of the oscillators for separations much greater than an optical wavelength.more » However, for such separations, the interaction energy cannot be transformed into an integral over the positive imaginary axis. If the argument theorem is used incorrectly to relate the interaction energy to an integral over the positive imaginary axis, the interaction energy is non-oscillatory and varies as r{sup −4}, a result found by several authors. Rather remarkably, this incorrect expression for the dispersion energy actually corresponds to the nonperturbative Casimir-Polder energy for a ground-state quantum oscillator near a perfectly conducting wall, as we show using the so-called “remarkable formula” for the free energy of an oscillator coupled to a heat bath [G. W. Ford, J. T. Lewis, and R. F. O’Connell, Phys. Rev. Lett. 55, 2273 (1985)]. A derivation of that formula from basic results of statistical mechanics and the independent oscillator model of a heat bath is presented.« less

  17. On the relationship between positive and negative affect: Their correlation and their co-occurrence.

    PubMed

    Larsen, Jeff T; Hershfield, Hal E; Stastny, Bradley J; Hester, Neil

    2017-03-01

    Understanding the nature of emotional experience requires understanding the relationship between positive and negative affect. Two particularly important aspects of that relationship are the extent to which positive and negative affect are correlated with one another and the extent to which they co-occur. Some researchers have assumed that weak negative correlations imply greater co-occurrence (i.e., more mixed emotions) than do strong negative correlations, but others have noted that correlations may imply very little about co-occurrence. We investigated the relationship between the correlation between positive and negative affect and co-occurrence. Participants in each of 2 samples provided moment-to-moment happiness and sadness ratings as they watched an evocative film and listened to music. Results indicated (a) that 4 measures of the correlation between positive and negative affect were quite highly related to 1 another; (b) that the strength of the correlation between measures of mixed emotions varied considerably; (c) that correlational measures were generally (but not always) weakly correlated with mixed emotion measures; and (d) that bittersweet stimuli consistently led to elevations in mixed emotion measures but did not consistently weaken the correlation between positive and negative affect. Results highlight that the correlation between positive and negative affect and their co-occurrence are distinct aspects of the relationship between positive and negative affect. Such insight helps clarify the implications of existing work on age-related and cultural differences in emotional experience and sets the stage for greater understanding of the experience of mixed emotions. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  18. Immobilization of paracetamol and benzocaine pro-drug derivatives as long-range self-organized monolayers on graphite.

    PubMed

    Popoff, Alexandre; Fichou, Denis

    2008-05-01

    We show here by means of scanning tunneling microscopy (STM) at the liquid/solid interface that paracetamol and benzocaine molecules bearing a long aliphatic chain can be immobilized on highly oriented pyrolitic graphite (HOPG) as perfectly ordered two-dimensional domains extending over several hundreds of nanometers. In both cases, high-resolution STM images reveal that compounds 1 and 2 self-assemble into parallel lamellae having a head-to-head arrangement. The paracetamol heads of 1 are in a zigzag position with entangled n-dodecyloxy side chains while benzocaine heads of compound 2 are perfectly aligned as a double row and have their palmitic side chains on either sides of the head alignment. We attribute the very long-range ordering of these two pro-drug derivatives on HOPG to the combined effects of intermolecular H-bonding on one side and Van der Waals interactions between aliphatic side chains and graphite on the other side. The 2D immobilization of pro-drug derivatives via a non-destructive physisorption mechanism could prove to be useful for applications such as drug delivery if it can be realized on a biocompatible substrate.

  19. Comparison of two automated instruments for Epstein-Barr virus serology in a large adult hospital and implementation of an Epstein-Barr virus nuclear antigen-based testing algorithm.

    PubMed

    Al Sidairi, Hilal; Binkhamis, Khalifa; Jackson, Colleen; Roberts, Catherine; Heinstein, Charles; MacDonald, Jimmy; Needle, Robert; Hatchette, Todd F; LeBlanc, Jason J

    2017-11-01

    Serology remains the mainstay for diagnosis of Epstein-Barr virus (EBV) infection. This study compared two automated platforms (BioPlex 2200 and Architect i2000SR) to test three EBV serological markers: viral capsid antigen (VCA) immunoglobulins of class M (IgM), VCA immunoglobulins of class G (IgG) and EBV nuclear antigen-1 (EBNA-1) IgG. Using sera from 65 patients at various stages of EBV disease, BioPlex demonstrated near-perfect agreement for all EBV markers compared to a consensus reference. The agreement for Architect was near-perfect for VCA IgG and EBNA-1 IgG, and substantial for VCA IgM despite five equivocal results. Since the majority of testing in our hospital was from adults with EBNA-1 IgG positive results, post-implementation analysis of an EBNA-based algorithm showed advantages over parallel testing of the three serologic markers. This small verification demonstrated that both automated systems for EBV serology had good performance for all EBV markers, and an EBNA-based testing algorithm is ideal for an adult hospital.

  20. Topological framework for local structure analysis in condensed matter

    PubMed Central

    Lazar, Emanuel A.; Han, Jian; Srolovitz, David J.

    2015-01-01

    Physical systems are frequently modeled as sets of points in space, each representing the position of an atom, molecule, or mesoscale particle. As many properties of such systems depend on the underlying ordering of their constituent particles, understanding that structure is a primary objective of condensed matter research. Although perfect crystals are fully described by a set of translation and basis vectors, real-world materials are never perfect, as thermal vibrations and defects introduce significant deviation from ideal order. Meanwhile, liquids and glasses present yet more complexity. A complete understanding of structure thus remains a central, open problem. Here we propose a unified mathematical framework, based on the topology of the Voronoi cell of a particle, for classifying local structure in ordered and disordered systems that is powerful and practical. We explain the underlying reason why this topological description of local structure is better suited for structural analysis than continuous descriptions. We demonstrate the connection of this approach to the behavior of physical systems and explore how crystalline structure is compromised at elevated temperatures. We also illustrate potential applications to identifying defects in plastically deformed polycrystals at high temperatures, automating analysis of complex structures, and characterizing general disordered systems. PMID:26460045

  1. [Research in palliative care; is something better than nothing?].

    PubMed

    van Delden, J J M Hans

    2012-01-01

    How strictly should we apply the rules of good clinical research, when the research in question is performed with terminally ill patients? Recently, a retrospective study into the effectiveness of radiotherapy for sialorrhoea in patients with a degenerative disease, such as amyotrophic lateral sclerosis, was published in the Nederlands Tijdschrift voor Geneeskunde(Dutch Journal of Medicine). This commentary defends the position that in palliative care sometimes having weak scientific evidence is better than having nothing. Here, the need of the patient and the intention of the physician are 2 ethically relevant issues that need to be taken into account. If there is at least some evidence to believe an intervention is beneficial for the patient, this is a strong reason to provide it. And if such intervention can only be studied in a methodologically suboptimal way, then it is better to have that information, albeit not perfect, than none at all. This is not a justification of weak studies as such. If possible, palliative care should be as evidence-based as all other types of medical care. However, when the circumstances make methodologically perfect research impossible, it is better to act on weak evidence than on none at all.

  2. Lattice structures and electronic properties of MO/MoSe2 interface from first-principles calculations

    NASA Astrophysics Data System (ADS)

    Zhang, Yu; Tang, Fu-Ling; Xue, Hong-Tao; Lu, Wen-Jiang; Liu, Jiang-Fei; Huang, Min

    2015-02-01

    Using first-principles plane-wave calculations within density functional theory, we theoretically studied the atomic structure, bonding energy and electronic properties of the perfect Mo (110)/MoSe2 (100) interface with a lattice mismatch less than 4.2%. Compared with the perfect structure, the interface is somewhat relaxed, and its atomic positions and bond lengths change slightly. The calculated interface bonding energy is about -1.2 J/m2, indicating that this interface is very stable. The MoSe2 layer on the interface has some interface states near the Fermi level, the interface states are mainly caused by Mo 4d orbitals, while the Se atom almost have no contribution. On the interface, Mo-5s and Se-4p orbitals hybridize at about -6.5 to -5.0 eV, and Mo-4d and Se-4p orbitals hybridize at about -5.0 to -1.0 eV. These hybridizations greatly improve the bonding ability of Mo and Se atom in the interface. By Bader charge analysis, we find electron redistribution near the interface which promotes the bonding of the Mo and MoSe2 layer.

  3. Crosswell electromagnetic modeling from impulsive source: Optimization strategy for dispersion suppression in convolutional perfectly matched layer

    PubMed Central

    Fang, Sinan; Pan, Heping; Du, Ting; Konaté, Ahmed Amara; Deng, Chengxiang; Qin, Zhen; Guo, Bo; Peng, Ling; Ma, Huolin; Li, Gang; Zhou, Feng

    2016-01-01

    This study applied the finite-difference time-domain (FDTD) method to forward modeling of the low-frequency crosswell electromagnetic (EM) method. Specifically, we implemented impulse sources and convolutional perfectly matched layer (CPML). In the process to strengthen CPML, we observed that some dispersion was induced by the real stretch κ, together with an angular variation of the phase velocity of the transverse electric plane wave; the conclusion was that this dispersion was positively related to the real stretch and was little affected by grid interval. To suppress the dispersion in the CPML, we first derived the analytical solution for the radiation field of the magneto-dipole impulse source in the time domain. Then, a numerical simulation of CPML absorption with high-frequency pulses qualitatively amplified the dispersion laws through wave field snapshots. A numerical simulation using low-frequency pulses suggested an optimal parameter strategy for CPML from the established criteria. Based on its physical nature, the CPML method of simply warping space-time was predicted to be a promising approach to achieve ideal absorption, although it was still difficult to entirely remove the dispersion. PMID:27585538

  4. Some interesting examples of binormal degeneracy and analysis using a contaminated binormal ROC model

    NASA Astrophysics Data System (ADS)

    Berbaum, Kevin S.; Dorfman, Donald D.

    2001-06-01

    Receiver operating characteristic (ROC) data with false positive fractions of zero are often difficult to fit with standard ROC methodology, and are sometimes discarded. Some extreme examples of such data were analyzed. A new ROC model is proposed that assumes that for a proportion of abnormalities, no signal information is captured and that those abnormalities have the same distribution as noise along the latent decision axis. Rating reports of fracture for single view ankle radiographs were also analyzed with the binormal ROC model and two proper ROC models. The conventional models gave ROC area close to one, implying a true positive fraction close to one. The data contained no such fractions. When all false positive fractions were zero, conventional ROC areas gave little or no hint of unmistakable differences in true positive fractions. In contrast, the new model can fit ROC data in which some or all of the ROC points have false positive fractions of zero and true positive fractions less than one without concluding perfect performance. These data challenge the validity and robustness of conventional ROC models, but the contaminated binormal model accounts for these data. This research has been published for a different audience.

  5. Uganda: Perfection of Post-Conflict Stability or Ticking Time Bomb

    DTIC Science & Technology

    2016-01-01

    1 UGANDA: PERFECTION OF POST-CONFLICT STABILITY OR TICKING TIME BOMB ? By Kristin M. Pearson and Alex S. Pedersen, United States Air...Force Academy 2015 INSS RESEARCH PAPER 2016 2 UGANDA: PERFECTION OF POST-CONFLICT STABILITY OR TICKING TIME BOMB ? By Kristin M. Pearson and Alex...likely. “The area is a ticking time bomb without ongoing efforts. There’s an entire group of young men trained in military tactics that have said

  6. [INVITED] Coherent perfect absorption of electromagnetic wave in subwavelength structures

    NASA Astrophysics Data System (ADS)

    Yan, Chao; Pu, Mingbo; Luo, Jun; Huang, Yijia; Li, Xiong; Ma, Xiaoliang; Luo, Xiangang

    2018-05-01

    Electromagnetic (EM) absorption is a common process by which the EM energy is transformed into other kinds of energy in the absorber, for example heat. Perfect absorption of EM with structures at subwavelength scale is important for many practical applications, such as stealth technology, thermal control and sensing. Coherent perfect absorption arises from the interplay of interference and absorption, which can be interpreted as a time-reversed process of lasing or EM emitting. It provides a promising way for complete absorption in both nanophotonics and electromagnetics. In this review, we discuss basic principles and properties of a coherent perfect absorber (CPA). Various subwavelength structures including thin films, metamaterials and waveguide-based structures to realize CPAs are compared. We also discuss the potential applications of CPAs.

  7. Intersession and Intrasession Reliability and Validity of the My Jump App for Measuring Different Jump Actions in Trained Male and Female Athletes.

    PubMed

    Gallardo-Fuentes, Francisco; Gallardo-Fuentes, Jorge; Ramírez-Campillo, Rodrigo; Balsalobre-Fernández, Carlos; Martínez, Cristian; Caniuqueo, Alexis; Cañas, Rodrigo; Banzer, Winfried; Loturco, Irineu; Nakamura, Fabio Y; Izquierdo, Mikel

    2016-07-01

    Gallardo-Fuentes, F, Gallardo-Fuentes, J, Ramírez-Campillo, R, Balsalobre-Fernández, C, Martínez, C, Caniuqueo, A, Cañas, R, Banzer, W, Loturco, I, Nakamura, FY, and Izquierdo, M. Intersession and intrasession reliability and validity of the My Jump app for measuring different jump actions in trained male and female athletes. J Strength Cond Res 30(7): 2049-2056, 2016-The purpose of this study was to analyze the concurrent validity and reliability of the iPhone app named My Jump for measuring jump height in 40-cm drop jumps (DJs), countermovement jumps (CMJs), and squat jumps (SJs). To do this, 21 male and female athletes (age, 22.1 ± 3.6 years) completed 5 maximal DJs, CMJs, and SJs on 2 separate days, which were evaluated using a contact platform and the app My Jump, developed to calculate jump height from flight time using the high-speed video recording facility on the iPhone. A total of 630 jumps were compared using the intraclass correlation coefficient (ICC), Bland-Altman plots, Pearson's product moment correlation coefficient (r), Cronbach's alpha (α), and coefficient of variation (CV). There was almost perfect agreement between the measurement instruments for all jump height values (ICC = 0.97-0.99), with no differences between the instruments (p > 0.05; mean difference of 0.2 cm). Almost perfect correlation was observed between the measurement instruments for SJs, CMJs, and DJs (r = 0.96-0.99). My Jump showed very good within-subject reliability (α = 0.94-0.99; CV = 3.8-7.6) and interday reliability (r = 0.86-0.95) for SJs, CMJs, and DJs in all subjects. Therefore, the iPhone app named My Jump provides reliable intersession and intrasession data, as well as valid measurements for maximal jump height during fast (i.e., DJs) and slow (i.e., CMJs) stretch-shortening cycle muscle actions, and during concentric-only explosive muscle actions (i.e., SJs), in both male and female athletes in comparison with a professional contact platform.

  8. A perfect storm: examining the synergistic effects of negative and positive emotional instability on promoting weight loss activities in anorexia nervosa

    PubMed Central

    Selby, Edward A.; Cornelius, Talea; Fehling, Kara B.; Kranzler, Amy; Panza, Emily A.; Lavender, Jason M.; Wonderlich, Stephen A.; Crosby, Ross D.; Engel, Scott G.; Mitchell, James E.; Crow, Scott J.; Peterson, Carol B.; Grange, Daniel Le

    2015-01-01

    Growing evidence indicates that both positive and negative emotion potentially influence the development and maintenance of anorexia nervosa, through both positive and negative reinforcement of weight loss activities. Such reactive emotional experience may be characterized by frequent and intense fluctuations in emotion, a construct known as “emotional instability.” The purpose of this study was to investigate the association between positive emotional instability and weight loss activities in anorexia nervosa, and to investigate the synergistic effects of positive and negative emotional instability on promoting weight loss activities. Using ecological momentary assessment methods, 118 participants with anorexia nervosa reported their emotional experiences and behaviors at least six times daily over 2 weeks using a portable digital device. Using generalized linear modeling, results indicated that high levels of both positive and negative emotional instability, and the interaction between the two, were associated with more frequent weight-loss activities, beyond anorexia subtype and mean levels of emotional intensity. These findings indicate that when women with anorexia exhibit both high levels of both positive and negative emotional instability they are more prone to a variety of weight loss activities. The importance of addressing the role of both positive and negative emotion in anorexia treatment is discussed. PMID:26379588

  9. [Prediction of perceived health status on job stress and family stress with middle school teachers].

    PubMed

    Park, Hyoung Sook; Jeong, Seong Hee; Park, Kyung Yeon

    2007-06-01

    The purpose of this study was to identify the relationship among job stress, family stress and perceived health status of middle school teachers and to present basic information about promoting health and coping with stress. Participants(N=547) was recruited in B city from November 2005 to December 2005. Data were analyzed with descriptive statistics, t-test, ANOVA, Pearson's correlation and multiple regression. The degree of job stress of the middle school teachers was 54.47 out of a total score of 88; that of family stress was 46.57 out of a total score of 96; and that of perceived health status was 78.59 out of the perfect score 100. There was a significantly negative relationship between job stress and perceived health status (r=-.274, p<.001), and family stress and perceived health status(r=-.408, p<.001). However, there was a positive relationship between job stress and family stress(r=.298, p<.001). Family stress, gender, charging subject, job stress, charging grade and number of family member was 27.1% of the variance in perceived health status of middle school teachers. Family stress has the most important impact on perceived health status with middle school teachers. Based on the finding, we could conclude that both job stress and family stress management should be required to improve perceived health status.

  10. Human migration activities drive the fluctuation of ARGs: Case study of landfills in Nanjing, eastern China.

    PubMed

    Sun, Mingming; Ye, Mao; Schwab, Arthur P; Li, Xu; Wan, Jinzhong; Wei, Zhong; Wu, Jun; Friman, Ville-Petri; Liu, Kuan; Tian, Da; Liu, Manqiang; Li, Huixin; Hu, Feng; Jiang, Xin

    2016-09-05

    Landfills are perfect sites to study the effect of human migration on fluctuation of antibiotic resistance genes (ARGs) as they are the final destination of municipal waste. For example, large-scale human migration during the holidays is often accompanied by changes in waste dumping having potential effects on ARG abundance. Three landfills were selected to examine fluctuation in the abundance of fifteen ARGs and Intl1 genes for 14 months in Nanjing, eastern China. Mass human migration, the amount of dumped waste and temperature exerted the most significant effects on bimonthly fluctuations of ARG levels in landfill sites. As a middle-sized cosmopolitan city in China, millions of college students and workers migrate during holidays, contributing to the dramatic increases in waste production and fluctuation in ARG abundances. In line with this, mass migration explained most of the variation in waste dumping. The waste dumping also affected the bioaccessibility of mixed-compound pollutants that further positively impacted the level of ARGs. The influence of various bioaccessible compounds on ARG abundance followed the order: antibiotics>nutrients>metals>organic pollutants. Concentrations of bioaccessible compounds were more strongly correlated with ARG levels compared to total compound concentrations. Improved waste classification and management strategies could thus help to decrease the amount of bioaccessible pollutants leading to more effective control for urban ARG dissemination. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Visualization of postoperative anterior cruciate ligament reconstruction bone tunnels

    PubMed Central

    2011-01-01

    Background and purpose Non-anatomic bone tunnel placement is the most common cause of a failed ACL reconstruction. Accurate and reproducible methods to visualize and document bone tunnel placement are therefore important. We evaluated the reliability of standard radiographs, CT scans, and a 3-dimensional (3D) virtual reality (VR) approach in visualizing and measuring ACL reconstruction bone tunnel placement. Methods 50 consecutive patients who underwent single-bundle ACL reconstructions were evaluated postoperatively by standard radiographs, CT scans, and 3D VR images. Tibial and femoral tunnel positions were measured by 2 observers using the traditional methods of Amis, Aglietti, Hoser, Stäubli, and the method of Benereau for the VR approach. Results The tunnel was visualized in 50–82% of the standard radiographs and in 100% of the CT scans and 3D VR images. Using the intraclass correlation coefficient (ICC), the inter- and intraobserver agreement was between 0.39 and 0.83 for the standard femoral and tibial radiographs. CT scans showed an ICC range of 0.49–0.76 for the inter- and intraobserver agreement. The agreement in 3D VR was almost perfect, with an ICC of 0.83 for the femur and 0.95 for the tibia. Interpretation CT scans and 3D VR images are more reliable in assessing postoperative bone tunnel placement following ACL reconstruction than standard radiographs. PMID:21999625

  12. Estimation of positive semidefinite correlation matrices by using convex quadratic semidefinite programming.

    PubMed

    Fushiki, Tadayoshi

    2009-07-01

    The correlation matrix is a fundamental statistic that is used in many fields. For example, GroupLens, a collaborative filtering system, uses the correlation between users for predictive purposes. Since the correlation is a natural similarity measure between users, the correlation matrix may be used in the Gram matrix in kernel methods. However, the estimated correlation matrix sometimes has a serious defect: although the correlation matrix is originally positive semidefinite, the estimated one may not be positive semidefinite when not all ratings are observed. To obtain a positive semidefinite correlation matrix, the nearest correlation matrix problem has recently been studied in the fields of numerical analysis and optimization. However, statistical properties are not explicitly used in such studies. To obtain a positive semidefinite correlation matrix, we assume the approximate model. By using the model, an estimate is obtained as the optimal point of an optimization problem formulated with information on the variances of the estimated correlation coefficients. The problem is solved by a convex quadratic semidefinite program. A penalized likelihood approach is also examined. The MovieLens data set is used to test our approach.

  13. Clinical Results After Prostatic Artery Embolization Using the PErFecTED Technique: A Single-Center Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Amouyal, Gregory, E-mail: gregamouyal@hotmail.com; Thiounn, Nicolas, E-mail: nicolas.thiounn@aphp.fr; Pellerin, Olivier, E-mail: olivier.pellerin@aphp.fr

    BackgroundProstatic artery embolization (PAE) has been performed for a few years, but there is no report on PAE using the PErFecTED technique outside from the team that initiated this approach.ObjectiveThis single-center retrospective open label study reports our experience and clinical results on patients suffering from symptomatic BPH, who underwent PAE aiming at using the PErFecTED technique.Materials and MethodsWe treated 32 consecutive patients, mean age 65 (52–84 years old) between December 2013 and January 2015. Patients were referred for PAE after failure of medical treatment and refusal or contra-indication to surgery. They were treated using the PErFecTED technique, when feasible, with 300–500 µmmore » calibrated microspheres (two-night hospital stay or outpatient procedure). Follow-up was performed at 3, 6, and 12 months.ResultsWe had a 100 % immediate technical success of embolization (68 % of feasibility of the PErFecTED technique) with no immediate complications. After a mean follow-up of 7.7 months, we observed a 78 % rate of clinical success. Mean IPSS decreased from 15.3 to 4.2 (p = .03), mean QoL from 5.4 to 2 (p = .03), mean Qmax increased from 9.2 to 19.2 (p = .25), mean prostatic volume decreased from 91 to 62 (p = .009) mL. There was no retrograde ejaculation and no major complication.ConclusionPAE using the PErFecTED technique is a safe and efficient technique to treat bothersome LUTS related to BPH. It is of interest to note that the PErFecTED technique cannot be performed in some cases for anatomical reasons.« less

  14. Evaluation of the LIA-ANA-Profile-17S for the detection of autoantibodies to nuclear antigens.

    PubMed

    Yi, Ahram; Lee, Chang-Hoon; Moon, Hee-Won; Kim, Hanah; Hur, Mina; Yun, Yeo-Min

    2018-05-01

    The diagnostic tests for autoimmune disease include screening for autoantibodies for nuclear antigens (ANA) and antibodies against extractable nuclear antigens (ENA). Using the line immunoassay (LIA) method, various kinds of ENA antibodies can be detected simultaneously. We evaluated the performance of the newly launched LIA-ANA-Profile-17S (Shenzhen YHLO Biotech, Shenzhen, China) as compared to a conventional LIA kit. Residual samples were collected from 200 patients who had been tested for ANA using indirect immunofluorescence. The LIA-ANA-Profile-17S was compared to the EuroLine ANA (Euroimmun, Oberlausitz, Germany) for the analysis of 17 different autoantibodies. The concordance rate and agreement between assays were determined. Samples showing discrepancies between the LIA-ANA-Profile-17S and EuroLine tests were further examined through additional analysis. The overall agreement was moderate (kappa = 0.759, 95% CI = 0.712-0.805). Agreement between assays ranged from weak to almost perfect, except for those tests targeting nucleosomes, histones, and PM-Scl. Of the 57 disparate results between LIA-ANA-Profile-17S and EuroLine, 38 (66.7%) samples tested positive under an additional assay, showing variable patterns between types of autoantibodies. The positive rate of each autoantibody between LIA-ANA-Profile-17S and EuroLine did not differ significantly, except for anti-nucleosome and anti-histone assays in samples from patients diagnosed with systemic lupus erythematosus (P = 0.004 and 0.001, respectively). Compared to those from the conventional EuroLine assay, the LIA-ANA-Profile-17S results showed variable agreement in samples showing different prevalence of each autoantibody. The most frequently detected antibodies showed almost perfect agreement. The LIA-ANA-Profile-17S could play a role in the diagnosis of systemic autoimmune disease in ANA-positive samples. Copyright © 2018 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  15. Why can't a woman be more like a man? A renaissance perspective on the biological basis for female inferiority.

    PubMed

    Walton, M T; Fineman, R M; Walton, P J

    1996-01-01

    Western biomedical theory supported the idea of human female inferiority. The Aristotelian formulation was: Nature intends to produce the perfect male form with external genitalia; the female with internal genitalia is less than perfect and thus a defect of nature. In the Renaissance, peripubertal virilization in females was interpreted as further evidence that females were "defective" males capable of developing into the more perfect male form.

  16. Selective coherent perfect absorption in metamaterials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nie, Guangyu; Shi, Quanchao; Zhu, Zheng

    2014-11-17

    We show multi-band coherent perfect absorption (CPA) in simple bilayered asymmetrically split ring metamaterials. The selectivity of absorption can be accomplished by separately excited electric and magnetic modes in a standing wave formed by two coherent counterpropagating beams. In particular, each CPA can be completely switched on/off by the phase of a second coherent wave. We propose a practical scheme for realizing multi-band coherent perfect absorption of 100% that is allowed to work from microwave to optical frequency.

  17. Computation of Thermally Perfect Properties of Oblique Shock Waves

    NASA Technical Reports Server (NTRS)

    Tatum, Kenneth E.

    1996-01-01

    A set of compressible flow relations describing flow properties across oblique shock waves, derived for a thermally perfect, calorically imperfect gas, is applied within the existing thermally perfect gas (TPG) computer code. The relations are based upon a value of cp expressed as a polynomial function of temperature. The updated code produces tables of compressible flow properties of oblique shock waves, as well as the original properties of normal shock waves and basic isentropic flow, in a format similar to the tables for normal shock waves found in NACA Rep. 1135. The code results are validated in both the calorically perfect and the calorically imperfect, thermally perfect temperature regimes through comparisons with the theoretical methods of NACA Rep. 1135, and with a state-of-the-art computational fluid dynamics code. The advantages of the TPG code for oblique shock wave calculations, as well as for the properties of isentropic flow and normal shock waves, are its ease of use, and its applicability to any type of gas (monatomic, diatomic, triatomic, polyatomic, or any specified mixture thereof).

  18. Numerical Analysis of the Trailblazer Inlet Flowfield for Hypersonic Mach Numbers

    NASA Technical Reports Server (NTRS)

    Steffen, C. J., Jr.; DeBonis, J. R.

    1999-01-01

    A study of the Trailblazer vehicle inlet was conducted using the Global Air Sampling Program (GASP) code for flight Mach numbers ranging from 4-12. Both perfect gas and finite rate chemical analysis were performed with the intention of making detailed comparisons between the two results. Inlet performance was assessed using total pressure recovery and kinetic energy efficiency. These assessments were based upon a one-dimensional stream-thrust-average of the axisymmetric flowfield. Flow visualization utilized to examine the detailed shock structures internal to this mixed-compression inlet. Kinetic energy efficiency appeared to be the least sensitive to differences between the perfect gas and finite rate chemistry results. Total pressure recovery appeared to be the most sensitive discriminator between the perfect gas and finite rate chemistry results for flight Mach numbers above Mach 6. Adiabatic wall temperature was consistently overpredicted by the perfect gas model for flight Mach numbers above Mach 4. The predicted shock structures were noticeably different for Mach numbers from 6-12. At Mach 4, the perfect gas and finite rate chemistry models collapse to the same result.

  19. Universal scheme for finite-probability perfect transfer of arbitrary multispin states through spin chains

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Man, Zhong-Xiao, E-mail: zxman@mail.qfnu.edu.cn; An, Nguyen Ba, E-mail: nban@iop.vast.ac.vn; Xia, Yun-Jie, E-mail: yjxia@mail.qfnu.edu.cn

    In combination with the theories of open system and quantum recovering measurement, we propose a quantum state transfer scheme using spin chains by performing two sequential operations: a projective measurement on the spins of ‘environment’ followed by suitably designed quantum recovering measurements on the spins of interest. The scheme allows perfect transfer of arbitrary multispin states through multiple parallel spin chains with finite probability. Our scheme is universal in the sense that it is state-independent and applicable to any model possessing spin–spin interactions. We also present possible methods to implement the required measurements taking into account the current experimental technologies.more » As applications, we consider two typical models for which the probabilities of perfect state transfer are found to be reasonably high at optimally chosen moments during the time evolution. - Highlights: • Scheme that can achieve perfect quantum state transfer is devised. • The scheme is state-independent and applicable to any spin-interaction models. • The scheme allows perfect transfer of arbitrary multispin states. • Applications to two typical models are considered in detail.« less

  20. Translation, reliability, and clinical utility of the Melbourne Assessment 2.

    PubMed

    Gerber, Corinna N; Plebani, Anael; Labruyère, Rob

    2017-10-12

    The aims were to (i) provide a German translation of the Melbourne Assessment 2 (MA2), a quantitative test to measure unilateral upper limb function in children with neurological disabilities and (ii) to evaluate its reliability and aspects of clinical utility. After its translation into German and approval of the back translation by the original authors, the MA2 was performed and videotaped twice with 30 children with neuromotor disorders. For each participant, two raters scored the video of the first test for inter-rater reliability. To determine test-retest reliability, one rater additionally scored the video of the second test while the other rater repeated the scoring of the first video to evaluate intra-rater reliability. Time needed for rater training, test administration, and scoring was recorded. The four subscale scores showed excellent intra-, inter-rater, and test-retest reliability with intraclass correlation coefficients of 0.90-1.00 (95%-confidence intervals 0.78-1.00). Score items revealed substantial to almost perfect intra-rater reliability (weighted kappa k w  = 0.66-1.00) for the more affected side. Score item inter-rater and test-retest reliability of the same extremity were, with one exception, moderate to almost perfect (k w  = 0.42-0.97; k w  = 0.40-0.89). Furthermore, the MA2 was feasible and acceptable for patients and clinicians. The MA2 showed excellent subscale and moderate to almost perfect score item reliability. Implications for Rehabilitation There is a lack of high-quality studies about psychometric properties of upper limb measurement tools in the neuropediatric population. The Melbourne Assessment 2 is a promising tool for reliable measurement of unilateral upper limb movement quality in the neuropediatric population. The Melbourne Assessment 2 is acceptable and practicable to therapists and patients for routine use in clinical care.

  1. Validity and Interrater Reliability of the Visual Quarter-Waste Method for Assessing Food Waste in Middle School and High School Cafeteria Settings.

    PubMed

    Getts, Katherine M; Quinn, Emilee L; Johnson, Donna B; Otten, Jennifer J

    2017-11-01

    Measuring food waste (ie, plate waste) in school cafeterias is an important tool to evaluate the effectiveness of school nutrition policies and interventions aimed at increasing consumption of healthier meals. Visual assessment methods are frequently applied in plate waste studies because they are more convenient than weighing. The visual quarter-waste method has become a common tool in studies of school meal waste and consumption, but previous studies of its validity and reliability have used correlation coefficients, which measure association but not necessarily agreement. The aims of this study were to determine, using a statistic measuring interrater agreement, whether the visual quarter-waste method is valid and reliable for assessing food waste in a school cafeteria setting when compared with the gold standard of weighed plate waste. To evaluate validity, researchers used the visual quarter-waste method and weighed food waste from 748 trays at four middle schools and five high schools in one school district in Washington State during May 2014. To assess interrater reliability, researcher pairs independently assessed 59 of the same trays using the visual quarter-waste method. Both validity and reliability were assessed using a weighted κ coefficient. For validity, as compared with the measured weight, 45% of foods assessed using the visual quarter-waste method were in almost perfect agreement, 42% of foods were in substantial agreement, 10% were in moderate agreement, and 3% were in slight agreement. For interrater reliability between pairs of visual assessors, 46% of foods were in perfect agreement, 31% were in almost perfect agreement, 15% were in substantial agreement, and 8% were in moderate agreement. These results suggest that the visual quarter-waste method is a valid and reliable tool for measuring plate waste in school cafeteria settings. Copyright © 2017 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  2. Nitrotyrosine adsorption on defective graphene: A density functional theory study

    NASA Astrophysics Data System (ADS)

    Majidi, R.; Karami, A. R.

    2015-06-01

    We have applied density functional theory to study adsorption of nitrotyrosine on perfect and defective graphene sheets. The graphene sheets with Stone-Wales (SW) defect, pentagon-nonagon (5-9) single vacancy, and pentagon-octagon-pentagon (5-8-5) double vacancy were considered. The calculations of adsorption energy showed that nitrotyrosine presents a more strong interaction with defective graphene rather than with perfect graphene sheet. The order of interaction strength is: SW>5-9>5-8-5>perfect graphene. It is found that the electronic properties of perfect and defective graphene are sensitive to the presence of nitrotyrosine. Hence, graphene sheets can be considered as a good sensor for detection of nitrotyrosine molecule which is observed in connection with several human disorders, such as Parkinson's and Alzheimer's disease.

  3. Chiral tunneling in a twisted graphene bilayer.

    PubMed

    He, Wen-Yu; Chu, Zhao-Dong; He, Lin

    2013-08-09

    The perfect transmission in a graphene monolayer and the perfect reflection in a Bernal graphene bilayer for electrons incident in the normal direction of a potential barrier are viewed as two incarnations of the Klein paradox. Here we show a new and unique incarnation of the Klein paradox. Owing to the different chiralities of the quasiparticles involved, the chiral fermions in a twisted graphene bilayer show an adjustable probability of chiral tunneling for normal incidence: they can be changed from perfect tunneling to partial or perfect reflection, or vice versa, by controlling either the height of the barrier or the incident energy. As well as addressing basic physics about how the chiral fermions with different chiralities tunnel through a barrier, our results provide a facile route to tune the electronic properties of the twisted graphene bilayer.

  4. Validation of the Penn Acoustic Neuroma Quality-of-Life Scale (PANQOL) for Spanish-Speaking Patients.

    PubMed

    Medina, Maria Del Mar; Carrillo, Alvaro; Polo, Ruben; Fernandez, Borja; Alonso, Daniel; Vaca, Miguel; Cordero, Adela; Perez, Cecilia; Muriel, Alfonso; Cobeta, Ignacio

    2017-04-01

    Objective To perform translation, cross-cultural adaptation, and validation of the Penn Acoustic Neuroma Quality-of-Life Scale (PANQOL) to the Spanish language. Study Design Prospective study. Setting Tertiary neurotologic referral center. Subjects and Methods PANQOL was translated and translated back, and a pretest trial was performed. The study included 27 individuals diagnosed with vestibular schwannoma. Inclusion criteria were adults with untreated vestibular schwannoma, diagnosed in the past 12 months. Feasibility, internal consistency, test-retest reliability, construct validity, and ceiling and floor effects were assessed for the present study. Results The mean overall score of the PANQOL was 69.21 (0-100 scale, lowest to highest quality of life). Cronbach's α was 0.87. Intraclass correlation coefficient was performed for each item, with an overall score of 0.92. The κ coefficient scores were between moderate and almost perfect in more than 92% of patients. Anxiety and energy domains of the PANQOL were correlated with both physical and mental components of the SF-12. Hearing, balance, and pain domains were correlated with the SF-12 physical component. Facial and general domains were not significantly correlated with any component of the SF-12. Furthermore, the overall score of the PANQOL was correlated with the physical component of the SF-12. Conclusion Feasibility, internal consistency, reliability, and construct validity outcomes in the current study support the validity of the Spanish version of the PANQOL.

  5. Flow Function of Pharmaceutical Powders Is Predominantly Governed by Cohesion, Not by Friction Coefficients.

    PubMed

    Leung, Lap Yin; Mao, Chen; Srivastava, Ishan; Du, Ping; Yang, Chia-Yi

    2017-07-01

    The purpose of this study was to demonstrate that the flow function (FFc) of pharmaceutical powders, as measured by rotational shear cell, is predominantly governed by cohesion but not friction coefficients. Driven by an earlier report showing an inverse correlation between FFc and the cohesion divided by the corresponding pre-consolidation stress (Wang et al. 2016. Powder Tech. 294:105-112), we performed analysis on a large data set containing 1130 measurements from a ring shear tester and identified a near-perfect inverse correlation between the FFc and cohesion. Conversely, no correlation was found between FFc and friction angles. We also conducted theoretical analysis and estimated such correlations based on Mohr-Coulomb failure model. We discovered that the correlation between FFc and cohesion can sustain as long as the angle of internal friction at incipient flow is not significantly larger than the angle of internal friction at steady-state flow, a condition covering almost all pharmaceutical powders. The outcome of this study bears significance in pharmaceutical development. Because the cohesion value is strongly influenced by the interparticle cohesive forces, this study effectively shows that it is more efficient to improve the pharmaceutical powder flow by lowering the interparticle cohesive forces than by lowering the interparticle frictions. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  6. Construction of negative images of menstruation in Indian TV commercials.

    PubMed

    Yagnik, Arpan Shailesh

    2012-01-01

    Menstruation is a perfectly normal physiological process; however, it is problematized in TV commercials. In the current study, a thematic analysis of 50 Indian TV commercials was conducted to identify the latent themes. Social captivity, restrictions, professional inefficiency, and physical and mental discomfort emerged as major themes after the analysis. The knowledge that manufacturers use such themes for image building and creating a conducive buying environment may prevent the reinforcement of menstrual taboos in Indian society. It can also guide the manufacturers in ideating and creating positive and healthier ways of advertising female hygiene products.

  7. Muscle assembly: a titanic achievement?

    PubMed

    Gregorio, C C; Granzier, H; Sorimachi, H; Labeit, S

    1999-02-01

    The formation of perfectly aligned myofibrils in striated muscle represents a dramatic example of supramolecular assembly in eukaryotic cells. Recently, considerable progress has been made in deciphering the roles that titin, the third most abundant protein in muscle, has in this process. An increasing number of sarcomeric proteins (ligands) are being identified that bind to specific titin domains. Titin may serve as a molecular blueprint for sarcomere assembly and turnover by specifying the precise position of its ligands within each half-sarcomere in addition to functioning as a molecular spring that maintains the structural integrity of the contracting myofibrils.

  8. Development of 3D out-of-plane SU-8 microlenses using modified micromolding in capillaries (MIMIC) technology

    NASA Astrophysics Data System (ADS)

    Llobera, A.; Wilke, R.; Johnson, D. W.; Büttgenbach, S.

    2006-04-01

    This paper describes a modification of the standard MIMIC technology, solving its main drawbacks, to define arrays of spherical or ellipsoidal microlenses. Perfectly symmetrical meniscuses have been obtained by using a XP SU-8 NO-2 layer beneath the PDMS mold. Moreover, the photostructurable properties of this polymer allow obtaining self-alignment structures for adequate fiber optics positioning. Microchannels ended with these meniscuses have been filled with standard SU-8 to obtain 3D microlenses. Agreement between theory and experimental results allows confirming the validity of the proposed technology.

  9. Phase locked loop synchronization for direct detection optical PPM communication systems

    NASA Technical Reports Server (NTRS)

    Chen, C. C.; Gardner, C. S.

    1985-01-01

    Receiver timing synchronization of an optical pulse position modulation (PPM) communication system can be achieved using a phase locked loop (PLL) if the photodetector output is properly processed. The synchronization performance is shown to improve with increasing signal power and decreasing loop bandwidth. Bit error rate (BER) of the PLL synchronized PPM system is analyzed and compared to that for the perfectly synchronized system. It is shown that the increase in signal power needed to compensate for the imperfect synchronization is small (less than 0.1 dB) for loop bandwidths less than 0.1% of the slot frequency.

  10. Plasma equilibrium control during slow plasma current quench with avoidance of plasma-wall interaction in JT-60U

    NASA Astrophysics Data System (ADS)

    Yoshino, R.; Nakamura, Y.; Neyatani, Y.

    1997-08-01

    In JT-60U a vertical displacement event (VDE) is observed during slow plasma current quench (Ip quench) for a vertically elongated divertor plasma with a single null. The VDE is generated by an error in the feedback control of the vertical position of the plasma current centre (ZJ). It has been perfectly avoided by improving the accuracy of the ZJ measurement in real time. Furthermore, plasma-wall interaction has been avoided successfully during slow Ip quench owing to the good performance of the plasma equilibrium control system

  11. Surface Area of Patellar Facets: Inferential Statistics in the Iraqi Population

    PubMed Central

    Al-Zamili, Zaid; Omar, Rawan

    2017-01-01

    Background. The patella is the largest sesamoid bone in the body; its three-dimensional complexity necessitates biomechanical perfection. Numerous pathologies occur at the patellofemoral unit which may end in degenerative changes. This study aims to test the presence of statistical correlation between the surface areas of patellar facets and other patellar morphometric parameters. Materials and Methods. Forty dry human patellae were studied. The morphometry of each patella was measured using a digital Vernier Caliper, electronic balance, and image analyses software known as ImageJ. The patellar facetal surface area was correlated with patellar weight, height, width, and thickness. Results. Inferential statistics proved the existence of linear correlation of total facetal surface area and patellar weight, height, width, and thickness. The correlation was strongest for surface area versus patellar weight. The lateral facetal area was found persistently larger than the medial facetal area, the p value was found to be <0.001 (one-tailed t-test) for right patellae, and another significant p value of < 0.001 (one-tailed t-test) was found for left patellae. Conclusion. These data are vital for the restoration of the normal biomechanics of the patellofemoral unit; these are to be consulted during knee surgeries and implant designs and can be of an indispensable anthropometric, interethnic, and biometric value. PMID:28348891

  12. Active plasma release experiments

    NASA Technical Reports Server (NTRS)

    1986-01-01

    A pulse code modulator (PCM) encoder capable of storing data onboard into the mass memory in the encoder at up to 12 megabits per second was designed and constructed. This telemetry system was programed for two successful flights. All parts of the electronic system functioned perfectly during both previous flights and the detectors performed perfectly. However, in the first flight in Pokerflat, Alaska, an electron arm did not deploy for reasons as yet unkown. The ion arm deployed perfectly and good data was acquired.

  13. SU-E-J-46: Evaluation of the Accuracy of a Six Degree of Freedom Robotic Couch Using ConeBeam CT Images of the Isocal Phantom

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Q; Driewer, J; Wang, S

    Purpose The accuracy of Varian PerfectPitch six degree of freedom (DOF) robotic couch was examined using Varian Isocal phantom and cone-beam CT (CBCT) system. Methods CBCT images of the Isocal phantom were taken at different pitch and roll angles. The pitch and roll angles were varied from 357 to 3 degrees in one degree increments by input from service console, generating a total of 49 combinations with couch angle (yaw) zero. The center positions of the 16 tungsten carbide BBs contained in the Isocal were determined with in-house image processing software. Expected BBs positions at different rotation angles were determinedmore » mathematically by applying a combined translation/rotation operator to BB positions at zero pitch and roll values. A least square method was used to minimize the difference between the expected BB positions and their measured positions. In this way rotation angles were obtained and compared with input values from the console. Results A total of 49 CBCT images with voxel sizes 0.51 mm × 0.51 mm × 1 mm were used in analysis. Among the 49 calculations, the maximum rotation angle differences were 0.1 degree, 0.15 degree, and 0.09 degree, for pitch, roll, and couch rotation, respectively. The mean ± standard-deviation angle differences were 0.028±0.001 degree, −0.043±0.003 degree, and −0.009±0.001 degree, for pitch, roll, and couch rotation, respectively. The maximum isocenter shifts were 0.3 mm, 0.5 mm, 0.4 mm in x, y, z direction respectively following IEC6127 convention. The mean isocenter shifts were 0.07±0.02 mm, −0.05±0.06 mm, and −0.12±0.02 mm in x, y and z directions. Conclusion The accuracy of the Varian PerfectPitch six DOF couch was studied with CBCTs of the Isocal phantom. The rotational errors were less than 0.15 degree and isocenter shifts were less than 0.5 mm in any direction. This accuracy is sufficient for stereotactic radiotherapy clinical applications.« less

  14. Time-frequency wavelet analysis of the interrelationship between the global macro assets and the fear indexes

    NASA Astrophysics Data System (ADS)

    Abid, Fathi; Kaffel, Bilel

    2018-01-01

    Understanding the interrelationships of the global macro assets is crucial for global macro investing. This paper investigates the local variance and the interconnection between the stock, gold, oil, Forex and the implied volatility markets in the time/frequency domains using the wavelet methodology, including the wavelet power spectrum, the wavelet squared coherence and phase difference, the wavelet multiple correlation and cross-correlation. The univariate analysis reveals that, in some crisis periods, underlying asset markets present the same pattern in terms of the wavelet power spectrum indicating high volatility for the medium scale, and that for the other market stress periods, volatility behaves differently. Moreover, unlike the underlying asset markets, the implied volatility markets are characterized by high power regions across the entire period, even in the absence of economic events. Bivariate results show a bidirectional relationship between the underlying assets and their corresponding implied volatility indexes, and a steady co-movement between the stock index and its corresponding fear index. Multiple correlation analysis indicates a strong correlation between markets at high scales with evidence of a nearly perfect integration for a period longer than a year. In addition, the hedging strategies based on the volatility index lead to an increase in portfolio correlation. On the other hand, the results from multiple cross-correlations reveal that the lead-lag effect starts from the medium scale and that the VIX (stock market volatility index) index is the potential leader or follower of the other markets.

  15. Superconducting bearings for application in cryogenic experiments in space

    NASA Technical Reports Server (NTRS)

    Everitt, C. W. F.; Worden, P. W., Jr.

    1980-01-01

    Linear superconducting magnetic bearings suitable for use in a proposed orbital equivalence principle experiment and for general application in space were developed and tested. Current flows in opposite directions in adjacent superconducting wires arranged parallel to the axis of a cylinder. This configuration provides maximum stiffness radially while allowing the test mass to move freely along the cylinder axis. In a space application, the wires are extended to cover the entire perimeter of the cylinder: for the earth-based tests it was desirable to use only the bottom half. Control of the axial position of the test mass is by small control coils which may be positioned inside or outside the main bearing. The design is suitable for application to other geometries where maximum stiffness is desired. A working model scaled to operate in a 1-g environment was perfected approximate solutions for the bearings were developed. A superconducting transformer method of charging the magnets for the bearing, and a position detector based on a SQUID magnetometer and associated superconducting circuit were also investigated.

  16. Image-Based 3d Reconstruction and Analysis for Orthodontia

    NASA Astrophysics Data System (ADS)

    Knyaz, V. A.

    2012-08-01

    Among the main tasks of orthodontia are analysis of teeth arches and treatment planning for providing correct position for every tooth. The treatment plan is based on measurement of teeth parameters and designing perfect teeth arch curve which teeth are to create after treatment. The most common technique for teeth moving uses standard brackets which put on teeth and a wire of given shape which is clamped by these brackets for producing necessary forces to every tooth for moving it in given direction. The disadvantages of standard bracket technique are low accuracy of tooth dimensions measurements and problems with applying standard approach for wide variety of complex orthodontic cases. The image-based technique for orthodontic planning, treatment and documenting aimed at overcoming these disadvantages is proposed. The proposed approach provides performing accurate measurements of teeth parameters needed for adequate planning, designing correct teeth position and monitoring treatment process. The developed technique applies photogrammetric means for teeth arch 3D model generation, brackets position determination and teeth shifting analysis.

  17. Connecting Athletes’ Self-Perceptions and Metaperceptions of Competence: a Structural Equation Modeling Approach

    PubMed Central

    Cecchini, Jose A.; Fernández-Rio, Javier; Méndez-Giménez, Antonio

    2015-01-01

    This study explored the relationships between athletes’ competence self-perceptions and metaperceptions. Two hundred and fifty one student-athletes (14.26 ± 1.89 years), members of twenty different teams (basketball, soccer) completed a questionnaire which included the Perception of Success Questionnaire, the Competence subscale of the Intrinsic Motivation Inventory, and modified versions of both questionnaires to assess athletes’ metaperceptions. Structural equation modelling analysis revealed that athletes’ task and ego metaperceptions positively predicted task and ego self-perceptions, respectively. Competence metaperceptions were strong predictors of competence self-perceptions, confirming the atypical metaperception formation in outcome-dependent contexts such as sport. Task and ego metaperceptions positively predicted athletes’ competence metaperceptions. How coaches value their athletes’ competence is more influential on what the athletes think of themselves than their own self-perceptions. Athletes’ ego and task metaperceptions influenced their competence metaperceptions (how coaches rate their competence). Therefore, athletes build their competence metaperceptions using all information available from their coaches. Finally, only task-self perfections positively predicted athletes’ competence self-perceptions. PMID:26240662

  18. "I bet they aren't that perfect in reality:" Appearance ideals viewed from the perspective of adolescents with a positive body image.

    PubMed

    Holmqvist, Kristina; Frisén, Ann

    2012-06-01

    In this qualitative study, we examined the topic of appearance ideals from the perspective of 14-year-old adolescents (N=29) with a positive body image. A thematic analysis revealed that the adolescents with a positive body image were very critical against current ideals, describing them as unnatural and unrealistic, and criticizing media for only showing those consistent with the ideals and having underlying intentions with doing so. Instead, the adolescents defined beauty widely and flexibly, stressed the importance of looking like 'oneself', and conveyed the idea of personality as outplaying looks. The perception of beauty as subjective was also prominent. These results may be helpful when forming preventions targeting those at risk for developing negative body image, adding support for preventions based on media literacy and feminist theories. Additionally, we stress the significance of providing adolescents with alternative ways of thinking about ideals, beauty, and attractiveness. Copyright © 2012 Elsevier Ltd. All rights reserved.

  19. On the more accurate channel model and positioning based on time-of-arrival for visible light localization

    NASA Astrophysics Data System (ADS)

    Amini, Changeez; Taherpour, Abbas; Khattab, Tamer; Gazor, Saeed

    2017-01-01

    This paper presents an improved propagation channel model for the visible light in indoor environments. We employ this model to derive an enhanced positioning algorithm using on the relation between the time-of-arrivals (TOAs) and the distances for two cases either by assuming known or unknown transmitter and receiver vertical distances. We propose two estimators, namely the maximum likelihood estimator and an estimator by employing the method of moments. To have an evaluation basis for these methods, we calculate the Cramer-Rao lower bound (CRLB) for the performance of the estimations. We show that the proposed model and estimations result in a superior performance in positioning when the transmitter and receiver are perfectly synchronized in comparison to the existing state-of-the-art counterparts. Moreover, the corresponding CRLB of the proposed model represents almost about 20 dB reduction in the localization error bound in comparison with the previous model for some practical scenarios.

  20. Quantification of upper limb position sense using an exoskeleton and a virtual reality display.

    PubMed

    Deblock-Bellamy, Anne; Batcho, Charles Sebiyo; Mercier, Catherine; Blanchette, Andreanne K

    2018-03-16

    Proprioceptive sense plays a significant role in the generation and correction of skilled movements and, consequently, in most activities of daily living. We developed a new proprioception assessment protocol that enables the quantification of elbow position sense without using the opposite arm, involving active movement of the evaluated limb or relying on working memory. The aims of this descriptive study were to validate this assessment protocol by quantifying the elbow position sense of healthy adults, before using it in individuals who sustained a stroke, and to investigate its test-retest reliability. Elbow joint position sense was quantified using a robotic device and a virtual reality system. Two assessments were performed, by the same evaluator, with a one-week interval. While the participant's arms and hands were occluded from vision, the exoskeleton passively moved the dominant arm from an initial to a target position. Then, a virtual arm representation was projected on a screen placed over the participant's arm. This virtual representation and the real arm were not perfectly superimposed, however. Participants had to indicate verbally the relative position of their arm (more flexed or more extended; two-alternative forced choice paradigm) compared to the virtual representation. Each participant completed a total of 136 trials, distributed in three phases. The angular differences between the participant's arm and the virtual representation ranged from 1° to 27° and changed pseudo-randomly across trials. No feedback about results was provided to the participants during the task. A discrimination threshold was statistically extracted from a sigmoid curve fit representing the relationship between the angular difference and the percentage of successful trials. Test-retest reliability was evaluated with 3 different complementary approaches, i.e. a Bland-Altman analysis, an intraclass correlation coefficient (ICC) and a standard error of measurement (SEm). Thirty participants (24.6 years old; 17 males, 25 right-handed) completed both assessments. The mean discrimination thresholds were 7.0 ± 2.4 (mean ± standard deviation) and 5.9 ± 2.1 degrees for the first and the second assessment session, respectively. This small difference between assessments was significant (- 1.1 ± 2.2 degrees), however. The assessment protocol was characterized by a fair to good test-retest reliability (ICC = 0.47). This study demonstrated the potential of this assessment protocol to objectively quantify elbow position sense in healthy individuals. Futures studies will validate this protocol in older adults and in individuals who sustained a stroke.

  1. Drosophila mini-white model system: new insights into positive position effects and the role of transcriptional terminators and gypsy insulator in transgene shielding

    PubMed Central

    Silicheva, Margarita; Golovnin, Anton; Pomerantseva, Ekaterina; Parshikov, Aleksander; Georgiev, Pavel; Maksimenko, Oksana

    2010-01-01

    The white gene, which is responsible for eye pigmentation, is widely used to study position effects in Drosophila. As a result of insertion of P-element vectors containing mini-white without enhancers into random chromosomal sites, flies with different eye color phenotypes appear, which is usually explained by the influence of positive/negative regulatory elements located around the insertion site. We found that, in more than 70% of cases when mini-white expression was subject to positive position effects, deletion of the white promoter had no effect on eye pigmentation; in these cases, the transposon was inserted into the transcribed regions of genes. Therefore, transcription through the mini-white gene could be responsible for high levels of its expression in most of chromosomal sites. Consistently with this conclusion, transcriptional terminators proved to be efficient in protecting mini-white expression from positive position effects. On the other hand, the best characterized Drosophila gypsy insulator was poorly effective in terminating transcription and, as a consequence, only partially protected mini-white expression from these effects. Thus, to ensure maximum protection of a transgene from position effects, a perfect boundary/insulator element should combine three activities: to block enhancers, to provide a barrier between active and repressed chromatin, and to terminate transcription. PMID:19854952

  2. What grades and achievement tests measure.

    PubMed

    Borghans, Lex; Golsteyn, Bart H H; Heckman, James J; Humphries, John Eric

    2016-11-22

    Intelligence quotient (IQ), grades, and scores on achievement tests are widely used as measures of cognition, but the correlations among them are far from perfect. This paper uses a variety of datasets to show that personality and IQ predict grades and scores on achievement tests. Personality is relatively more important in predicting grades than scores on achievement tests. IQ is relatively more important in predicting scores on achievement tests. Personality is generally more predictive than IQ on a variety of important life outcomes. Both grades and achievement tests are substantially better predictors of important life outcomes than IQ. The reason is that both capture personality traits that have independent predictive power beyond that of IQ.

  3. What grades and achievement tests measure

    PubMed Central

    Borghans, Lex; Golsteyn, Bart H. H.; Heckman, James J.; Humphries, John Eric

    2016-01-01

    Intelligence quotient (IQ), grades, and scores on achievement tests are widely used as measures of cognition, but the correlations among them are far from perfect. This paper uses a variety of datasets to show that personality and IQ predict grades and scores on achievement tests. Personality is relatively more important in predicting grades than scores on achievement tests. IQ is relatively more important in predicting scores on achievement tests. Personality is generally more predictive than IQ on a variety of important life outcomes. Both grades and achievement tests are substantially better predictors of important life outcomes than IQ. The reason is that both capture personality traits that have independent predictive power beyond that of IQ. PMID:27830648

  4. Temperature dependent optical properties of single, hierarchically self-assembled GaAs/AlGaAs quantum dots

    PubMed Central

    Rastelli, A; Schmidt, OG; Ulrich, SM; Michler, P

    2006-01-01

    We report on the experimental observation of bright photoluminescence emission at room temperature from single unstrained GaAs quantum dots (QDs). The linewidth of a single-QD ground-state emission (≈ 8.5 meV) is comparable to the ensemble inhomogeneous broadening (≈ 12.4 meV). At low temperature (T ≤ 40 K) photon correlation measurements under continuous wave excitation show nearly perfect single-photon emission from a single GaAs QD and reveal the single photon nature of the emitted light up to 77 K. The QD emission energies, homogeneous linewidths and the thermally activated behavior as a function of temperature are discussed.

  5. Assessment of historical masonry pillars reinforced by CFRP strips

    NASA Astrophysics Data System (ADS)

    Fedele, Roberto; Rosati, Giampaolo; Biolzi, Luigi; Cattaneo, Sara

    2014-10-01

    In this methodological study, the ultimate response of masonry pillars strengthened by externally bonded Carbon Fiber Reinforced Polymer (CFRP) was investigated. Historical bricks were derived from a XVII century rural building, whilst a high strength mortar was utilized for the joints. The conventional experimental information, concerning the overall reaction force and relative displacements provided by "point" sensors (LVDTs and clip gauge), were herein enriched with no-contact, full-field kinematic measurements provided by 2D Digital Image Correlation (2D DIC). Experimental information were critically compared with prediction provided by an advanced three-dimensional models, based on nonlinear finite elements under the simplifying assumption of perfect adhesion between the reinforcement and the support.

  6. Double resonance calibration of g factor standards: Carbon fibers as a high precision standard

    NASA Astrophysics Data System (ADS)

    Herb, Konstantin; Tschaggelar, Rene; Denninger, Gert; Jeschke, Gunnar

    2018-04-01

    The g factor of paramagnetic defects in commercial high performance carbon fibers was determined by a double resonance experiment based on the Overhauser shift due to hyperfine coupled protons. Our carbon fibers exhibit a single, narrow and perfectly Lorentzian shaped ESR line and a g factor slightly higher than gfree with g = 2.002644 =gfree · (1 + 162ppm) with a relative uncertainty of 15ppm . This precisely known g factor and their inertness qualify them as a high precision g factor standard for general purposes. The double resonance experiment for calibration is applicable to other potential standards with a hyperfine interaction averaged by a process with very short correlation time.

  7. Modelling directional solidification

    NASA Technical Reports Server (NTRS)

    Wilcox, William R.

    1987-01-01

    An improved understanding of the phenomena of importance to directional solidification is attempted to enable explanation and prediction of differences in behavior between solidification on Earth and in space. Emphasis is now on experimentally determining the influence of convection and freezing rate fluctuations on compositional homogeneity and crystalline perfection. A correlation is sought between heater temperature profiles, buoyancy-driven convection, and doping inhomogeneities using naphthalene doped with anthracene. The influence of spin-up/spin-down is determined on compositional homogeneity and microstructure of indium gallium antimonide. The effect is determined of imposed melting - freezing cycles on indium gallium antimonide. The mechanism behind the increase of grain size caused by using spin-up/spin-down in directional solidification of mercury cadimum telluride is sought.

  8. Local complexity predicts global synchronization of hierarchically networked oscillators

    NASA Astrophysics Data System (ADS)

    Xu, Jin; Park, Dong-Ho; Jo, Junghyo

    2017-07-01

    We study the global synchronization of hierarchically-organized Stuart-Landau oscillators, where each subsystem consists of three oscillators with activity-dependent couplings. We considered all possible coupling signs between the three oscillators, and found that they can generate different numbers of phase attractors depending on the network motif. Here, the subsystems are coupled through mean activities of total oscillators. Under weak inter-subsystem couplings, we demonstrate that the synchronization between subsystems is highly correlated with the number of attractors in uncoupled subsystems. Among the network motifs, perfect anti-symmetric ones are unique to generate both single and multiple attractors depending on the activities of oscillators. The flexible local complexity can make global synchronization controllable.

  9. Quantum dynamics modeled by interacting trajectories

    NASA Astrophysics Data System (ADS)

    Cruz-Rodríguez, L.; Uranga-Piña, L.; Martínez-Mesa, A.; Meier, C.

    2018-03-01

    We present quantum dynamical simulations based on the propagation of interacting trajectories where the effect of the quantum potential is mimicked by effective pseudo-particle interactions. The method is applied to several quantum systems, both for bound and scattering problems. For the bound systems, the quantum ground state density and zero point energy are shown to be perfectly obtained by the interacting trajectories. In the case of time-dependent quantum scattering, the Eckart barrier and uphill ramp are considered, with transmission coefficients in very good agreement with standard quantum calculations. Finally, we show that via wave function synthesis along the trajectories, correlation functions and energy spectra can be obtained based on the dynamics of interacting trajectories.

  10. Measurement-based quantum teleportation on finite AKLT chains

    NASA Astrophysics Data System (ADS)

    Fujii, Akihiko; Feder, David

    In the measurement-based model of quantum computation, universal quantum operations are effected by making repeated local measurements on resource states which contain suitable entanglement. Resource states include two-dimensional cluster states and the ground state of the Affleck-Kennedy-Lieb-Tasaki (AKLT) state on the honeycomb lattice. Recent studies suggest that measurements on one-dimensional systems in the Haldane phase teleport perfect single-qubit gates in the correlation space, protected by the underlying symmetry. As laboratory realizations of symmetry-protected states will necessarily be finite, we investigate the potential for quantum gate teleportation in finite chains of a bilinear-biquadratic Hamiltonian which is a generalization of the AKLT model representing the full Haldane phase.

  11. Micromechanical modeling of damage growth in titanium based metal-matrix composites

    NASA Technical Reports Server (NTRS)

    Sherwood, James A.; Quimby, Howard M.

    1994-01-01

    The thermomechanical behavior of continuous-fiber reinforced titanium based metal-matrix composites (MMC) is studied using the finite element method. A thermoviscoplastic unified state variable constitutive theory is employed to capture inelastic and strain-rate sensitive behavior in the Timetal-21s matrix. The SCS-6 fibers are modeled as thermoplastic. The effects of residual stresses generated during the consolidation process on the tensile response of the composites are investigated. Unidirectional and cross-ply geometries are considered. Differences between the tensile responses in composites with perfectly bonded and completely debonded fiber/matrix interfaces are discussed. Model simulations for the completely debonded-interface condition are shown to correlate well with experimental results.

  12. Notes on wall crossing and instanton in compactified gauge theory with matter

    NASA Astrophysics Data System (ADS)

    Chen, Heng-Yu; Petunin, Kirill

    2010-10-01

    We study the quantum effects on the Coulomb branch of mathcal{N} = 2 SU(2) super-symmetric Yang-Mills with fundamental matters compactified on {mathbb{R}^3} × {S^1} , and extract the explicit perturbative and leading non-perturbative corrections to the moduli space metric predicted from the recent work of Gaiotto, Moore and Neitzke on wall-crossing [1]. We verify the predicted metric by computing the leading weak coupling instanton contribution to the four fermion correlation using standard field theory techniques, and demonstrate perfect agreement. We also demonstrate how previously known three dimensional quantities can be recovered in appropriate small radius limit, and provide a simple geometric picture from brane construction.

  13. Comparing diagnostic tests on benefit-risk.

    PubMed

    Pennello, Gene; Pantoja-Galicia, Norberto; Evans, Scott

    2016-01-01

    Comparing diagnostic tests on accuracy alone can be inconclusive. For example, a test may have better sensitivity than another test yet worse specificity. Comparing tests on benefit risk may be more conclusive because clinical consequences of diagnostic error are considered. For benefit-risk evaluation, we propose diagnostic yield, the expected distribution of subjects with true positive, false positive, true negative, and false negative test results in a hypothetical population. We construct a table of diagnostic yield that includes the number of false positive subjects experiencing adverse consequences from unnecessary work-up. We then develop a decision theory for evaluating tests. The theory provides additional interpretation to quantities in the diagnostic yield table. It also indicates that the expected utility of a test relative to a perfect test is a weighted accuracy measure, the average of sensitivity and specificity weighted for prevalence and relative importance of false positive and false negative testing errors, also interpretable as the cost-benefit ratio of treating non-diseased and diseased subjects. We propose plots of diagnostic yield, weighted accuracy, and relative net benefit of tests as functions of prevalence or cost-benefit ratio. Concepts are illustrated with hypothetical screening tests for colorectal cancer with test positive subjects being referred to colonoscopy.

  14. Frozen Chemistry Effects on Nozzle Performance Simulations

    NASA Technical Reports Server (NTRS)

    Yoder, Dennis A.; Georgiadis, Nicholas J.; O'Gara, Michael R.

    2009-01-01

    Simulations of exhaust nozzle flows are typically conducted assuming the gas is calorically perfect, and typically modeled as air. However the gas inside a real nozzle is generally composed of combustion products whose thermodynamic properties may differ. In this study, the effect of gas model assumption on exhaust nozzle simulations is examined. The three methods considered model the nozzle exhaust gas as calorically perfect air, a calorically perfect exhaust gas mixture, and a frozen exhaust gas mixture. In the latter case the individual non-reacting species are tracked and modeled as a gas which is only thermally perfect. Performance parameters such as mass flow rate, gross thrust, and thrust coefficient are compared as are mean flow and turbulence profiles in the jet plume region. Nozzles which operate at low temperatures or have low subsonic exit Mach numbers experience relatively minor temperature variations inside the nozzle, and may be modeled as a calorically perfect gas. In those which operate at the opposite extreme conditions, variations in the thermodynamic properties can lead to different expansion behavior within the nozzle. Modeling these cases as a perfect exhaust gas flow rather than air captures much of the flow features of the frozen chemistry simulations. Use of the exhaust gas reduces the nozzle mass flow rate, but has little effect on the gross thrust. When reporting nozzle thrust coefficient results, however, it is important to use the appropriate gas model assumptions to compute the ideal exit velocity. Otherwise the values obtained may be an overly optimistic estimate of nozzle performance.

  15. Adaptive Distributed Video Coding with Correlation Estimation using Expectation Propagation

    PubMed Central

    Cui, Lijuan; Wang, Shuang; Jiang, Xiaoqian; Cheng, Samuel

    2013-01-01

    Distributed video coding (DVC) is rapidly increasing in popularity by the way of shifting the complexity from encoder to decoder, whereas no compression performance degrades, at least in theory. In contrast with conventional video codecs, the inter-frame correlation in DVC is explored at decoder based on the received syndromes of Wyner-Ziv (WZ) frame and side information (SI) frame generated from other frames available only at decoder. However, the ultimate decoding performances of DVC are based on the assumption that the perfect knowledge of correlation statistic between WZ and SI frames should be available at decoder. Therefore, the ability of obtaining a good statistical correlation estimate is becoming increasingly important in practical DVC implementations. Generally, the existing correlation estimation methods in DVC can be classified into two main types: pre-estimation where estimation starts before decoding and on-the-fly (OTF) estimation where estimation can be refined iteratively during decoding. As potential changes between frames might be unpredictable or dynamical, OTF estimation methods usually outperforms pre-estimation techniques with the cost of increased decoding complexity (e.g., sampling methods). In this paper, we propose a low complexity adaptive DVC scheme using expectation propagation (EP), where correlation estimation is performed OTF as it is carried out jointly with decoding of the factor graph-based DVC code. Among different approximate inference methods, EP generally offers better tradeoff between accuracy and complexity. Experimental results show that our proposed scheme outperforms the benchmark state-of-the-art DISCOVER codec and other cases without correlation tracking, and achieves comparable decoding performance but with significantly low complexity comparing with sampling method. PMID:23750314

  16. Adaptive distributed video coding with correlation estimation using expectation propagation

    NASA Astrophysics Data System (ADS)

    Cui, Lijuan; Wang, Shuang; Jiang, Xiaoqian; Cheng, Samuel

    2012-10-01

    Distributed video coding (DVC) is rapidly increasing in popularity by the way of shifting the complexity from encoder to decoder, whereas no compression performance degrades, at least in theory. In contrast with conventional video codecs, the inter-frame correlation in DVC is explored at decoder based on the received syndromes of Wyner-Ziv (WZ) frame and side information (SI) frame generated from other frames available only at decoder. However, the ultimate decoding performances of DVC are based on the assumption that the perfect knowledge of correlation statistic between WZ and SI frames should be available at decoder. Therefore, the ability of obtaining a good statistical correlation estimate is becoming increasingly important in practical DVC implementations. Generally, the existing correlation estimation methods in DVC can be classified into two main types: pre-estimation where estimation starts before decoding and on-the-fly (OTF) estimation where estimation can be refined iteratively during decoding. As potential changes between frames might be unpredictable or dynamical, OTF estimation methods usually outperforms pre-estimation techniques with the cost of increased decoding complexity (e.g., sampling methods). In this paper, we propose a low complexity adaptive DVC scheme using expectation propagation (EP), where correlation estimation is performed OTF as it is carried out jointly with decoding of the factor graph-based DVC code. Among different approximate inference methods, EP generally offers better tradeoff between accuracy and complexity. Experimental results show that our proposed scheme outperforms the benchmark state-of-the-art DISCOVER codec and other cases without correlation tracking, and achieves comparable decoding performance but with significantly low complexity comparing with sampling method.

  17. Adaptive Distributed Video Coding with Correlation Estimation using Expectation Propagation.

    PubMed

    Cui, Lijuan; Wang, Shuang; Jiang, Xiaoqian; Cheng, Samuel

    2012-10-15

    Distributed video coding (DVC) is rapidly increasing in popularity by the way of shifting the complexity from encoder to decoder, whereas no compression performance degrades, at least in theory. In contrast with conventional video codecs, the inter-frame correlation in DVC is explored at decoder based on the received syndromes of Wyner-Ziv (WZ) frame and side information (SI) frame generated from other frames available only at decoder. However, the ultimate decoding performances of DVC are based on the assumption that the perfect knowledge of correlation statistic between WZ and SI frames should be available at decoder. Therefore, the ability of obtaining a good statistical correlation estimate is becoming increasingly important in practical DVC implementations. Generally, the existing correlation estimation methods in DVC can be classified into two main types: pre-estimation where estimation starts before decoding and on-the-fly (OTF) estimation where estimation can be refined iteratively during decoding. As potential changes between frames might be unpredictable or dynamical, OTF estimation methods usually outperforms pre-estimation techniques with the cost of increased decoding complexity (e.g., sampling methods). In this paper, we propose a low complexity adaptive DVC scheme using expectation propagation (EP), where correlation estimation is performed OTF as it is carried out jointly with decoding of the factor graph-based DVC code. Among different approximate inference methods, EP generally offers better tradeoff between accuracy and complexity. Experimental results show that our proposed scheme outperforms the benchmark state-of-the-art DISCOVER codec and other cases without correlation tracking, and achieves comparable decoding performance but with significantly low complexity comparing with sampling method.

  18. Validation of the Automatic Thoughts Questionnaire (ATQ) Among Mainland Chinese Students in Hong Kong.

    PubMed

    Pan, Jia-Yan; Ye, Shengquan; Ng, Petrus

    2016-01-01

    The present study validated the combined version of the 8-item Automatic Thought Questionnaire (ATQ) and 10 positive items from the ATQ-revised among Chinese university students. A total of 412 Mainland Chinese university students were recruited in Hong Kong by an online survey. A 14-item Chinese ATQ was derived via item analysis. Satisfactory internal consistency reliability and good split-half reliability were obtained. Exploratory and confirmatory factor analysis revealed a 3-correlated-factor solution for the Chinese ATQ: negative thought, positive thought (emotional), and positive thought (cognitive). The negative ATQ subscale score was positively correlated with negative affect, and negatively correlated with positive affect and life satisfaction. The two positive ATQ subscale scores were negatively correlated with negative affect, and positively correlated with positive affect and life satisfaction. The 14-item ATQ is a valid and reliable instrument for measuring automatic thoughts in the Chinese context of Hong Kong. © 2015 Wiley Periodicals, Inc.

  19. Towards ultrafast dynamics with split-pulse X-ray photon correlation spectroscopy at free electron laser sources

    DOE PAGES

    Roseker, W.; Hruszkewycz, S. O.; Lehmkuhler, F.; ...

    2018-04-27

    One of the important challenges in condensed matter science is to understand ultrafast, atomic-scale fluctuations that dictate dynamic processes in equilibrium and non-equilibrium materials. Here, we report an important step towards reaching that goal by using a state-of-the-art perfect crystal based split-and-delay system, capable of splitting individual X-ray pulses and introducing femtosecond to nanosecond time delays. We show the results of an ultrafast hard X-ray photon correlation spectroscopy experiment at LCLS where split X-ray pulses were used to measure the dynamics of gold nanoparticles suspended in hexane. We show how reliable speckle contrast values can be extracted even from verymore » low intensity free electron laser (FEL) speckle patterns by applying maximum likelihood fitting, thus demonstrating the potential of a split-and-delay approach for dynamics measurements at FEL sources. This will enable the characterization of equilibrium and, importantly also reversible non-equilibrium processes in atomically disordered materials.« less

  20. Psychological, physical, and academic correlates of cyberbullying and traditional bullying.

    PubMed

    Kowalski, Robin M; Limber, Susan P

    2013-07-01

    To examine the relationship between children's and adolescents' experiences with cyberbullying and traditional bullying and psychological health, physical health, and academic performance. Nine hundred thirty-one students in grades 6 through 12 completed an anonymous survey examining their experiences with cyberbullying and traditional bullying. Also included were measures of anxiety, depression, self-esteem, physical well-being, school attendance, and academic performance. Participants were categorized as belonging to one of four groups: cyber victims, cyberbullies, cyber bully/victims, and those not involved in cyberbullying. A similar categorization was done with traditional bullying. Those in the bully/victim groups (and particularly the cyber bully/victim group) had the most negative scores on most measures of psychological health, physical, health, and academic performance. There appears to be a substantial, although not perfect, overlap between involvement in traditional bullying and cyberbullying. Additionally, the physical, psychological, and academic correlates of the two types of bullying resembled one another. Copyright © 2013 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Top